最新美国发明专利第2021-06-01期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US11021730B2	In vitro glycosylation of proteins and enzymes The present invention is broadly concerned with new in vitro glycosylation methods that provide rational approaches for producing glycosylated proteins, and the use of glycosylated proteins. In more detail, the present invention comprises methods of glycosylating a starting protein having an amino sidechain with a nucleophilic moiety, comprising the step of reacting the protein with a carbohydrate having an oxazoline moiety on the reducing end thereof, to covalently bond the amino sidechain of the starting protein with the oxazoline moiety, wherein the glycosylated protein substantially retains the structure and function of the starting protein. Target proteins include oxidase, oxidoreductase and dehydrogenase enzymes. The glycosylated proteins advantageously have molecular weights of at least about 7500 Daltons. In a further embodiment, the present invention concerns the use of glycosylated proteins, fabricated by the methods disclosed herein, in the assembly of amperometric biosensors.
US11021729B2	Ketoreductase polypeptides and polynucleotides The present invention provides engineered ketoreductase and phosphite dehydrogenase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase and phosphite dehydrogenase enzymes, as well as polynucleotides encoding the engineered ketoreductase and phosphite dehydrogenase enzymes, host cells capable of expressing the engineered ketoreductase and phosphite dehydrogenase enzymes, and methods of using the engineered ketoreductase and phosphite dehydrogenase enzymes to synthesize a chiral catalyst used in the synthesis of antiviral compounds, such as nucleoside inhibitors. The present invention further provides methods of using the engineered enzymes to deracemize a chiral alcohol in a one-pot, multi-enzyme system.
US11021727B2	Efficient production of steviol glycosides in recombinant hosts Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes, or that overexpress one or more heterologous transporters, leading to increased excretions of steviol glucosides of interest.
US11021724B2	Materials and methods for alkene reduction of levoglucosenone by an alkene reductase The subject invention concerns materials and methods for alkene reduction of compounds, such as levoglucosenone (LGO) and (S)-γ-hydroxymethyl-α,β-butenolide (HBO), using an alkene reductase enzyme. In one embodiment, a method of the invention comprises alkene reduction of a target compound by reacting the compound with an Old Yellow Enzyme (OYE) that reduces alkene bonds. In one embodiment, the OYE is OYE 2.6 from Pichia stipites and comprises the amino acid sequence of SEQ ID NO: I. In a specific embodiment, the enzyme is an Old Yellow Enzyme (OYE) 2.6 mutant having an amino acid substitution at position 78 in the sequence, wherein the tyrosine at position 78 is substituted with a tryptophan amino acid (Y78W) and is designated as OYE 2.6 Y78W (SEQ ID NO:2).
US11021719B2	Methods and compositions for assessing CRISPER/Cas-mediated disruption or excision and CRISPR/Cas-induced recombination with an exogenous donor nucleic acid in vivo Methods and compositions are provided for assessing CRISPR/Cas-mediated non-homologous end joining (NHEJ) activity and/or CRISPR/Cas-induced recombination of a target genomic locus with an exogenous donor nucleic acid in vivo or ex vivo. The methods and compositions employ non-human animals comprising a CRISPR reporter such as a genomically integrated CRISPR reporter for detecting and measuring targeted excision of a sequence between two CRISPR/Cas nuclease cleavage sites or disruption of a sequence near a CRISPR/Cas nuclease cleavage site and/or measuring CRISPR/Cas-induced recombination of the CRISPR reporter with an exogenous donor nucleic acid to convert the coding sequence for a first reporter protein to the coding sequence for a different second reporter protein. Methods and compositions are also provided for making and using these non-human animals.
US11021716B2	Insecticidal proteins and methods for their use Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
US11021714B2	Nucleotide sequences and polypeptides encoded thereby useful for modifying plant characteristics in response to cold Methods and materials for modulating cold tolerance levels in plants are disclosed. For example, nucleic acids encoding cold tolerance-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased levels of cold tolerance and plant products produced from plants having increased cold tolerance levels.
US11021712B1	MiRNA mimics and uses thereof Among the various aspects of the present disclosure is the provision of miRNA mimics and uses thereof. An aspect of the present disclosure provides for compositions of miRNA mimic molecules and methods of treating metabolic disorders using miRNA mimic molecules.
US11021711B2	Genetic variations associated with drug resistance Methods and compositions are provided to determine if a cancer is resistant to treatment with anti-mitotic agents, including treatment with T-DM1. The methods relate to determining if the ABCC3 gene is amplified and/or overexpressed in the cancer.
US11021708B2	Methods and compositions for modulating splicing Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.
US11021707B2	Reduced size self-delivering nucleic acid compounds targeting long non-coding RNA The present disclosure relates to RNAi constructs with improved cellular uptake characteristics and methods of use of these compounds for silencing expression of long coding RNAs (IncRNAs).
US11021706B2	Antisense antibacterial compounds and methods Provided are antisense morpholino oligomers targeted against bacterial virulence factors such as genes that contribute to antibiotic resistance or biofilm formation, or genes associated with fatty acid biosynthesis, and related compositions and methods of using the oligomers and compositions, for instance, in the treatment of an infected mammalian subject.
US11021702B2	Method of producing a normalised nucleic acid library using solid state capture material The present invention provides a method of preparing a nucleic acid library, which includes providing a one or more nucleic acid samples, and a one or more of samples of solid state capture material; contacting each nucleic acid sample with a sample of capture material to provide captured nucleic acid samples; and pooling the captured nucleic acid samples to provide the nucleic acid library. The method is particularly suitable for preparing nucleic acids for sequencing, especially next generation sequencing and related methods such as genotyping-by-sequencing.
US11021700B2	Method for purifying viral vectors The invention relates to methods of purifying viral vectors from cell culture. In particular, the invention relates to a method of purifying a supernatant containing viral vectors from a cell culture by removing cells by filtering the cell culture using diatomaceous earth.
US11021698B2	Method and device for uniformly treating adherent cells Disclosed is a method for subjecting adherent cells to at least one electric field, in which the electric field is generated by applying a voltage to at least two active electrodes 63, wherein at least three electrodes 63, 64 are provided, and wherein at least two electrodes 63, 64 are active electrodes 63 when the voltage is applied in order to generate a first electric field, and in which at least one second electric field is generated, wherein at least one of the two previously active electrodes 63 is a potential-free electrode 64 when the voltage is applied. Also disclosed is a device 58 comprising at least three electrodes 63, 64, which are connected to at least one voltage source by means of at least one switching device 59, 60, 61, 62, wherein at least five electrodes 63, 64 are connected to the at least one voltage source by means of four switching devices 59, 60, 61, 62, wherein at least two electrodes 63, 64 are connected to the voltage source by means of a common switching device 59, 60, 61, 62. In conjunction with the method described above, the device according to the invention allows the efficient and uniform treatment of adherent cells using an electric field, wherein the switch between active and potential-free electrodes can be carried out quickly and safely using a lower number of switching devices.
US11021693B2	Dimeric reverse transcriptase Covalently-linked DNA polymerases are provided.
US11021690B2	Mutant-type uricase, PEG modified mutant-type uricase, and application thereof A mutant-type uricase, PEG modified mutant-type uricase, and application thereof. The mutant-type uricase has a cysteine residue introduced by recombination, the cysteine residue is located at an inactive region of the uricase, and one or more PEGs are coupled to the mutant-type uricase. The resulting PEGylated mutant-type uricase has characteristics of a half-life extension, product uniformity, and stable enzyme activity. Therefore, the present invention has a wide future application range.
US11021689B2	Recombinant adeno-associated virus particle purification comprising an affinity purification step The invention describes a method for obtaining purified recombinant Adeno-Associated Virus particles (rAAV), comprising the steps of: a) performing a depth filtration of a starting material previously obtained from cells producing rAAV particles, the said starting material being selected in a group comprising a cell lysate and a culture supernatant, whereby a rAAV-containing clarified composition is provided; b) submitting the rAAV-containing clarified composition to an affinity purification step, whereby a first rAAV enriched composition is provided; c) submitting the first rAAV enriched composition at least once to: c1) a step of anion-exchange chromatography on a chromatographic support wherein elution is performed by using a salt gradient, preferably a linear salt gradient, and wherein the rAAV-containing fraction is collected, whereby a second rAAV enriched composition is provided; or c2) a step of density gradient centrifugation, wherein the rAAV-containing fraction is collected, whereby a second rAAV enriched composition is provided; d) submitting the second rAAV enriched composition to a step of tangential flow filtration, whereby purified recombinant Adeno-Associated Virus particles (rAAV) are provided.
US11021686B2	In vitro production of cholangiocytes This invention relates to the efficient generation of cholangiocyte progenitor (CP) cells. Foregut stem cells (FSCs) are cultured in a hepatic induction medium comprising bone morphogenetic protein (BMP) and a TGFβ signalling inhibitor to produce a population of hepatoblasts. The hepatoblasts are then cultured in a biliary induction medium comprising fibroblast growth factor (FGF), retinoic acid and a TGFβ ligand to produce a population of cholangiocyte progenitors (CPs). The cholangiocyte progenitors (CPs) may be matured into cholangiocyte-like cells (CLCs) that display functional properties of Common Bile Duct (CBD) cholangiocytes. Methods, kits, cell populations and uses of these cell populations are provided.
US11021685B2	Osteoblasts and method for generating same An object of the present invention is to provide a method for generating an osteoblast that is applicable to repair of a bone defect due to various tumors, injuries, surgeries, etc. and to treatment for bone resorption typified by a periodontal disease, bone fracture, osteoporosis, etc., and that has a low risk of carcinogenesis. Provided as a means for achieving this object is a method for generating an osteoblast from a somatic cell of a mammal, the method comprising introducing Oct9 gene or an expression product thereof into the somatic cell.
US11021680B2	Detergent compositions containing a stabilized enzyme by phosphonates Detergent compositions that contain an enzyme, alkaline source, and phosphonate or amine phosphonate salt are described here. A use solution of the detergent compositions containing disclosed phosphonates can retain its enzyme activity for an extended period of time. Specifically, one specific type of phosphonates and another specific type of amine phosphonate salts were discovered to stabilize enzymes in detergent compositions. Solid detergent compositions that contain disclosed phosphonate or amine phosphonate salts are more effective to remove soils and can save production and use costs.
US11021678B2	Liquid detergent composition for hard surfaces Provided is a liquid detergent composition for hard surfaces which contains (a1) an amine oxide-type surfactant having at least one alkyl group or alkenyl group with 13 or more and 18 or less carbons [hereinafter, referred to as component (a1)]; and (b1) a sorbitan fatty acid ester in which the fatty acid residue has 10 or more and 18 or less carbons [hereinafter, referred to as component (b1)]; and water, wherein the mass ratio of the content of component (a1) to the content of component (b1), (a1)/(b1), is 0.4 or more.Also provided is a liquid detergent composition for hard surfaces which contains a surfactant in an amount of 0.1% by mass or more and 20% by mass or less; and water, wherein the liquid detergent composition contains, as the surfactant, (a2) an amine oxide-type surfactant having at least one alkyl group or alkenyl group with 7 or more and 12 or less carbons [hereinafter, referred to as component (a2)] and (b2) a glycerin fatty acid ester in which the fatty acid residue has 10 or more and 18 or less carbons [hereinafter, referred to as component (b2)], and wherein in the surfactant, the total content of the content of component (a2) and the content of component (b2) is 40% by mass or more.
US11021674B2	Rapid botanical oil distillation device utilizing microwave agent Various aspects of the disclosure relate to methods and systems for extracting plant oil from plant material. A system may comprise a microwave emitter, an extraction chamber, and a cooling chamber. Microwave radiation emitted by the microwave emitter may dielectrically heat a microwave absorbing agent, which may heat the plant oil of the plant material. Plant oil of the plant material may be volatized in the extraction chamber and may be directed into the cooling chamber to be condensed.
US11021673B2	Lubricant composition The invention provides a lubricating oil composition being a lubricating oil composition containing a base oil composition which includes a lubricant base oil belonging to Group 3 of the base oil categories specified by the American Petroleum Institute (API) and a comb-like polymethacrylate-based viscosity index improver wherein the weight-halving temperature is not less than 310° C., and the sulphur content in the aforementioned lubricating oil composition is not more than 0.3 weight % in terms of the total weight of the aforementioned lubricating oil composition, and the aforementioned lubricating oil composition has an SAE viscosity grade of 0W-20, 5W-20 or 5W-30, a viscosity index of not less than 185 and a high-temperature high-shear viscosity at 100° C. of not more than 7.5 mPa·s.
US11021672B2	Lubricant composition for speed reducer and speed reducer The invention provides a lubricant composition for an eccentrically oscillating speed reducer of planetary gear type, which is capable of extending the life of the speed reducer under high temperatures and keeping low input torque at low temperatures, and includes (a) a base oil containing a synthetic oil, (b) a hydrocarbon wax, and (c) at least one calcium salt selected from the group consisting of a calcium salt of petroleum sulfonic acid, a calcium salt of alkyl aromatic sulfonic acid, a calcium salt of oxidized wax, an overbasic calcium salt of petroleum sulfonic acid, an overbasic calcium salt of alkyl aromatic sulfonic acid, and an overbasic calcium salt of oxidized wax.
US11021671B2	Bearing flushing compositions and methods A bearing flushing composition includes a grease component and a solvent component. The grease component may include a grease thickener component, a base oil component, and, optionally, a performance additive component. The solvent component may include one or more solvent agents blended with the grease component.
US11021665B1	Two-stage recycle hydrocracking processes A two-stage recycle hydrocracking process may comprise hydrocracking at least a portion of a hydrocarbon feed to produce a first hydrocracked effluent, separating the first hydrocracked effluent into at least four separated effluents, hydrocracking at least a portion of the fourth separated effluent to produce a second hydrocracked effluent, and cooling the second hydrocracked effluent to a temperature less than or equal to 250 degrees Celsius to produce a cooled effluent. The second hydrocracking effluent may have a total concentration of aromatic compounds sufficient to maintain the solubility of heavy polynuclear aromatics in the second hydrocracked effluent and reduce precipitation of the heavy polynuclear aromatics in the second hydrocracked effluent. Processes for reducing or preventing the precipitation of heavy polynuclear aromatics during hydrocracking are also described.
US11021664B2	Hydrocracking system for producing distillate or naptha The invention relates to a catalytic hydrocracker with two different catalyst beds within the reactor where each is loaded with a catalyst that has different hydrocracking properties. A first catalyst bed preferably cracks heavy oil more aggressively than the catalyst in the second bed. The catalytic hydrocracker includes further two recycle lines such that one directs unconverted oil through both hydrocracker beds and a bypass inlet is positioned between the first and second catalyst beds to admit unconverted oil to pass only through the second less aggressive hydrocracker catalyst bed. When gasoline prices favor the production of gasoline, less unconverted oil is recycled through the bypass therefore making more gasoline, but when prices favor the production of j et and diesel, more recycle is directed through the bypass recycle thus making less gasoline and more diesel and jet fuel.
US11021663B2	Integrated enhanced solvent deasphalting and coking system to produce petroleum green coke An integrated system is provided for producing deasphalted oil, high quality petroleum green coke and liquid coker products. An enhanced solvent deasphalting system, is used to treat the feedstock to reduce the level of asphaltenes, N, S and metal contaminants and produce a deasphalted oil with reduced contaminants. A coking system is integrated to produce liquid and gas coking unit products, and petroleum green coke.
US11021661B2	Heavy fossil hydrocarbon conversion and upgrading using radio-frequency or microwave energy Conversion of heavy fossil hydrocarbons (HFH) to a variety of value-added chemicals and/or fuels can be enhanced using microwave (MW) and/or radio-frequency (RF) energy. Variations of reactants, process parameters, and reactor design can significantly influence the relative distribution of chemicals and fuels generated as the product. In one example, a system for flash microwave conversion of HFH includes a source concentrating microwave or RF energy in a reaction zone having a pressure greater than 0.9 atm, a continuous feed having HFH and a process gas passing through the reaction zone, a HFH-to-liquids catalyst contacting the HFH in at least the reaction zone, and dielectric discharges within the reaction zone. The HFH and the catalyst have a residence time in the reaction zone of less than 30 seconds. In some instances, a plasma can form in or near the reaction zone.
US11021660B2	Supercritical reactor systems and processes for petroleum upgrading Provided herein are supercritical upgrading reactors and reactor systems for upgrading a petroleum-based composition by using one or more supercritical upgrading reactors and one or more supercritical standby reactors that alternate functions such that the supercritical upgrading reactor is converted to a supercritical standby reactor and the supercritical standby reactor is converted to a supercritical upgrading reactor. The supercritical upgrading reactor upgrades a combined feed stream while a supercritical standby reactor delivers a cleaning fluid into the supercritical standby reactor. The supercritical reactors may have one or more catalyst layers and one or more purging fluid inlets, and the catalyst layers may have differing void volume ratios.
US11021659B2	Additives for supercritical water process to upgrade heavy oil A method of upgrading a petroleum feedstock, the method comprising the steps of introducing a disulfide oil, a water feed, and a petroleum feedstock to a supercritical water upgrading unit, and operating the supercritical water upgrading unit to produce a product gas stream, a product oil stream, and a used water stream.
US11021656B2	System and method to mitigate fouling during a hydrocarbon refining process Described herein are systems and methods for evaluating and mitigating the fouling potential of a given crude oil. The system and methods enable the refiner to rapidly and readily identify the particular mechanisms by which a crude oil may foul, and to select the optimal chemical treatment and/or crude blend to mitigate fouling potential.
US11021655B2	Decarbonization of coke ovens and associated systems and methods Systems and methods for removing carbonaceous clinker material from a coke oven are described. A coke oven can be provided including an oven floor, coke, and clinker material deposited on the oven floor. After a temperature of the coke oven has reached a first temperature (e.g., after heating coal in the oven to produce coke), the method includes increasing the temperature of the coke oven to a second temperature that is higher than the first temperature for a predetermined amount of time. After the predetermined amount of time, the temperature is reduced to a third temperature that is lower than the first temperature.
US11021654B2	Liquid crystal composition Disclosed is a liquid crystal composition comprising one or more compounds represented by formula I, one or more compounds represented by formula II, and one or more compounds represented by formula III: The liquid crystal composition has simultaneously a lower rotary viscosity, a better photoelectric performance, a higher clearing point, a good low temperature performance, and less display defects. Further disclosed is a liquid crystal display element or device comprising the liquid crystal composition.
US11021653B2	Lighting apparatus A LED device includes LED chips mounted on a substrate, a first fluorescent layer, a second fluorescent layer and a package housing. The LED chips emit a blue light. The first fluorescent layer has a first side facing to the LED chips for converting the blue light to a red light. The second fluorescent layer has a first side attached to a second side of the first fluorescent layer for converting the blue light to a red light emitted from a second side of the second fluorescent layer. The package housing holds the substrate and the first fluorescent layer.
US11021652B2	Phosphor particles with a protective layer, and method for producing the phosphor particles with the protective layer Phospher particles with a Protective Layer and a method for producing phosphor particles with a protective layer are disclosed. In an embodiment the method includes treating Si-containing and/or Al-containing phosphor with an acid solution, wherein a pH value of the acid solution is maintained within a range of pH 3.5 to pH 7 for a period of at least 1 h, wherein an Si-containing layer is formed on the phosphor particles, wherein the Si-containing layer has a higher content of Si on a surface than the phosphor particles, and/or wherein an Al-containing layer is formed on the phosphor particles, wherein the Al-containing layer has a modified content of aluminum on the surface than the phosphor particles and tempering the treated phosphor particles at a temperature of at least 100° C. thereby producing the protective layer.
US11021650B2	Compositions, quantum dot polymer composites prepared therefrom, and devices including the same A composition including a plurality of quantum dots; a binder polymer; a thiol compound having at least two thiol groups; a polyvalent metal compound; a polymerizable monomer having a carbon-carbon double bond; a photoinitiator; and a solvent.
US11021649B2	Flowback resistant proppants A resin coated proppant capable of self-bonding at temperatures as low as 70° F. (˜21° C.) is made from an aqueous dispersion of a self-bonding vinyl aromatic/acrylic ester addition copolymer.
US11021648B2	Energized natural gas foam delivery devices and methods Foaming formulations and methods and systems for using foaming formulations are disclosed. Concentric tubing can be positioned in a wellbore in a subterranean formation to position an exit orifice of the concentric tubing at a target zone. A foaming formulation can be injected through a first flow path of the concentric tubing and a blowing gas can be injected through a second flow path of the concentric tubing to maintain separation until the foaming formulation and the blowing gas exit the concentric tubing. Mixing of the foaming formulation and the blowing gas at the target zone can generate foam.
US11021645B2	Stabilization and reduction of TCT of divalent iodide-containing brines A composition for use in a wellbore activity, the composition comprising a stabilized divalent iodide brine, the stabilized divalent iodide brine comprises a divalent salt system, where the divalent salt system comprises a divalent iodide, an primary iodide stabilizer, the primary iodide stabilizer operable to remove free iodine, prevent the formation of free iodine, and suppress TCT, and an aqueous fluid, where the stabilized divalent iodide brine has a density greater than 11 lb/gal, where the stabilized divalent iodide brines has a TCT of less than or equal to 70 deg F.
US11021643B2	Organoclay composition and its use An organoclay composition which is a mineral clay or mineral clay mixture that has been treated with at least organic quaternary ammonium compound and a synergist comprising (i) an amine salt of a trimer acid, and (ii) an amine salt of a monocarboxylic fatty acid. The monocarboxylic fatty acid may be (a) at least one saturated carboxylic acid; and/or (b) at least one unsaturated carboxylic acid.
US11021639B2	HFO-1234yf inhibited solutions The present invention provides a composition comprising 2,3,3,3-tetrafluoropropene and γ-terpinene useful in automotive air conditioning systems and devices, commercial refrigeration systems and devices, chillers, residential refrigerator and freezers, general air conditioning systems, heat pumps, and the like.
US11021637B2	Adhesive for flexible optical film An adhesive for a flexible optical film, especially an acrylate pressure-sensitive adhesive for a flexible display device is disclosed. The shear storage modulus (G′(60° C./0.1 Hz)) at the temperature of 60° C. and the frequency of 0.1 Hz and the shear storage modulus (G′(30° C./1 Hz)) at the temperature of 30° C. and the frequency of 1 Hz of the present acrylate pressure-sensitive adhesive satisfy the relation: (G′(60° C./0.1 Hz)−G′(30° C./1 Hz))/G′(30° C./1 Hz)>−0.29, and the loss tangent (tan δ(60° C./0.1 Hz)) at the temperature of 60° C. and the frequency of 0.1 Hz and the loss tangent (tan δ(30° C./1 Hz)) at the temperature of 30° C. and the frequency of 1 Hz of the present acrylate pressure-sensitive adhesive satisfy the relation: (tan δ(60° C./0.1 Hz)−tan δ(30° C./1 Hz))/tan δ(30° C./1 Hz)<0.2.
US11021633B1	Snow equipment wax formulation A snow equipment wax composition including at least 65 wt % of candelilla wax and sunflower wax; at least 20 wt % of pillar blend soy wax; and up to 15 wt % of one or more additional materials selected from the group of additional waxes, natural plant oils, and hydrogenated plant oils.
US11021631B2	Aqueous coating composition The present invention provides the following aqueous coating composition. The aqueous coating composition comprises resin particles (A) having an average particle diameter of 300 to 1000 nm, a polyoxyalkylene group-containing polyol (B) having a number average molecular weight of 300 to 2000 and/or a diester compound (C), and a crosslinking agent (D); wherein the total solids content of the polyoxyalkylene group-containing polyol (B) and the diester compound (C) is 5 to 25 mass % based on the total solids content of the resin particles (A), the polyoxyalkylene group-containing polyol (B), the diester compound (C), and the crosslinking agent (D).
US11021623B2	Jet ink composition, method and coated article A jet ink composition, a jet ink coating method and a resulting jet ink coated article are all predicated upon the jet ink composition which includes in addition to a particulate pigment material and a solvent composition a resin composition. The resin composition includes an uncured silicone resin, an uncured epoxy resin and an uncured melamine resin. Upon thermal cure the uncured resin composition forms a cured resin composition with superior adhesion to substrates such as but not limited to glass substrates, ceramic substrates and metal oxide substrates.
US11021619B2	Ionic oligomer and polymerizable composition containing same for temporary-use water-fragmentable materials An oligomer bearing at least one crosslinkable ethylenic unsaturation and at least one ionic bond comprises in its structure at least one aminoacrylate group and at least one tertiary amine in a form salified with at least one carboxylic acid. Also described are a process for preparing a solution of the oligomer in a reactive diluent, a crosslinkable composition comprising the oligomer, the use thereof as binder in crosslinkable compositions for temporary-use water-removable materials in coatings, hydrogels and 3D object printing, and the crosslinked material which results from polymerizing the oligomer. As a temporary-use material, the cured oligomer can be easily removed after a temporary function, by simple cleaning with water and optionally at a suitable temperature greater than the glass transition temperature of the crosslinked product.
US11021618B2	Curable composition, laminate, and automobile headlamp lens Provided are: a curable composition that makes it possible to form a cured film having excellent wear resistance and weather resistance; a laminate that is provided with the cured film; and an automobile headlamp lens. The curable composition makes it possible to obtain a cured film in which the relationship between a haze value (ΔHx) that is obtained by a wear resistance test and a haze value (ΔHy) that is obtained by a weather resistance test satisfies ΔHy≤−0.3 ΔHx+5.0 when a cured film having a thickness of 10 μm is produced.
US11021617B2	Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof The disclosure relates to polymers including one or more 1,1-disubstitued alkene monomers. By employing a plurality of monomers and/or tailored chain structure, polymers having improved combinations of properties are achieved. The polymer may be a copolymer, preferably including two or more 1,1-disubstituted alkene monomers. The polymer may be a homopolymer having a tailored chain structure.
US11021616B2	Self-exposure method for surface of conductive particles anchored in polymer layer, method of fabricating anisotropic conductive film using the self-exposure method and the anisotropic conductive film Disclosed are a self-exposure method for a surface of conductive particles anchored in a polymer layer, a method of fabricating an anisotropic conductive film using the self-exposure method, and the anisotropic conductive film. A self-exposure method for a surface of conductive particles within a polymer layer may include controlling surface energy of multiple conductive particles so that a difference between surface energy of polymer to be used to fabricate the polymer layer and surface energy of the multiple conductive particles to be included in the polymer layer is a preset difference or more, forming a polymer solution by dissolving the polymer into a solvent in which the conductive particles having controlled surface energy have been mixed, and generating the polymer layer from which at least part of a surface of the multiple conductive particles has been externally exposed due to a difference in the surface energy by drying the polymer solution.
US11021614B1	Self-stratifying coatings A self-stratifying anticorrosive coating is described herein, including a zinc-rich epoxy, a curing agent chosen from the group consisting of amines, thiols, phenols, and carboxylic anhydrides, a binding agent chosen from the group consisting of aminoalkyl dialkoxysilane, dimethoxysilane, and aminoalkyl trialkoxysilane, a graphitic material, a solvent, and a water scavenge.
US11021608B2	Aqueous polyorganosiloxane hybrid resin dispersion An aqueous polyorganosiloxane hybrid resin dispersion can include at least one polyorganosiloxane hybrid resin, at least one amphiphilic emulsifier, and water.
US11021607B2	Metal-polyorganosiloxanes Metal-polyorganosiloxane materials, methods of making and using them, and manufactured articles and devices containing them are disclosed. The metal-polyorganosiloxane materials have improved thermal stability and comprises a metal-polyorganosiloxane mixture that is free of condensation-curable polyorganosiloxane and solid particles other than metal particles and ceramic particles, the metal-organosiloxane mixture otherwise comprising: (A) a polyorganosiloxane that is free of silicon-bonded organoheteryl groups; (B) a hydrocarbylene-based multipodal silane; and (C) metal particles.
US11021603B2	White polyester film with properties of lightweight and low-shrinkage A white polyester film with a specific weight of 0.6-1.2 has a three-layered structure containing two outer layers (A) having a combined thickness taking up 2% to 30% of an overall thickness of the film and a middle layer (B), and having air-bubble cells in both the outer layers (A) and the middle layer (B). The outer layers (A) are formed from a polyester resin and inorganic particles. The middle layer (B) is formed of a polyester resin, modified polypropylene resin having a heat distortion temperature above 120° C. and a melt flow index (MI) of 0.2-1 g/10 minutes (at 230° C., with a load of 2.16 kg) via crosslinking with 0.1-3 wt % of peroxide with respect to the weight of the polypropylene resin, and inorganic particles.
US11021593B2	Rubber composition for additive manufacturing There is provided a rubber composition for additive manufacturing that allows rubber shaped articles to be favorably produced using an additive manufacturing apparatus. The rubber composition for additive manufacturing of the present invention comprises a liquid rubber.
US11021592B2	Inverse-freezing compositions and use thereof A composite comprised of: (i) at least one inverse freezing material, and (ii) an additive in the form of at least one solid particle. Articles made of the composites, and uses of the composites or the articles incorporating same, particularly for reducing incoming shockwaves, are also disclosed.
US11021591B2	Barrier additives The present invention relates to processes for making compatibilized high aspect ratio barrier additives and polymer compositions that comprise compatibilized high aspect ratio barrier additives. The invention also relates to compositions produced by these processes, and articles formed from polymer compositions of this invention. The barrier additives provide passive barriers to gas molecules such as oxygen and carbon dioxide minimizing transit of such molecules through sidewalls of polymer articles containing the barrier additives.
US11021588B2	Method for producing porous cellulose medium The present invention provides a technique for preparing a porous cellulose medium, through the gelation of a solution in which cellulose acetate as a raw material is dissolved, which does not cause a reaction involving the migration of substances. Specifically, a method for producing a porous cellulose medium is provided which includes the steps of gelling a flowable homogeneous composition containing cellulose acetate, an organic solvent, and water through a decrease in temperature; and hydrolyzing the cellulose acetate contained in the resulting gel.
US11021580B2	Process for efficient cross-linking of hyaluronic acid A process for manufacturing a cross-linked hyaluronic acid (HA) gel product is comprising the steps of: (a) preparing an aqueous mixture of HA and a cross-linking agent selected from multiepoxides and diepoxides; wherein the HA is dissolved in an aqueous solution containing 1-10% (w/w) inorganic hydroxide; and wherein the dissolved HA constitutes more than 10% (w/w) of the final mixture; and (b) subjecting the aqueous mixture to cross-linking conditions to allow the dissolved HA to react with the cross-linking agent so as to obtain a cross-linked HA gel product.
US11021578B2	Gel composition and production method therefor Provided is a production method for a gel composition including steps (1) to (3) mentioned below: step (1) of mixing at room temperature a partial degradation product of the galactose moiety of galactoxyloglucan and an aqueous solvent to obtain a mixture; step (2) of cooling or freezing the mixture obtained in step (1); and step (3) of gelling the mixture cooled or frozen in step (2) by heating to obtain a gel composition that includes the galactose-partial degradation product.
US11021573B2	Polyimide-forming compositions, methods of manufacture, and articles prepared therefrom A polyimide-forming composition includes a particulate polyimide precursor composition having an average particle size of 0.1 to 100 micrometers wherein the polyimide precursor composition comprises a substituted or unsubstituted C4-40 bisanhydride, and a substituted or unsubstituted divalent C1-20 diamine; an aqueous carrier; and a surfactant. A method of manufacturing an article including a polyimide includes the steps of forming a preform comprising the polyimide-forming composition; and heating the preform at a temperature and for a period of time effective to imidize the polyimide precursor composition and form the polyimide. An article prepared by the method, and a layer or coating including a polyimide and a surfactant are also described.
US11021572B2	Photosensitive resin composition, cured product of same, interlayer insulating film, surface protective film and electronic component Provided is a photosensitive resin composition containing; (A) a polymer having an acidic functional group or a substituent derived therefrom; (B) a photoreactive compound; (C) a solvent; and (D) a nitrogen-containing aromatic compound represented by the following general formula (1).
US11021567B2	Polyols for improved viscoelastic foams with reduced temperature sensitivity This invention relates to a process for preparing viscoelastic polyurethane foam in which the isocyanate-reactive component comprises a specific polyol blend, and to viscoelastic polyurethane foam wherein the isocyanate-reactive comprises the specific polyol blend. The polyol blend may be an in situ formed polyol blend.
US11021565B2	Silane modified polymers and use of the same in adhesive compositions Disclosed is a moisture curable silane modified terpolymer comprising a polyether segment, a segment of polytetrahydrofuran or polycarbonate, a polysiloxane segment and terminal amino silane groups joined to the terpolymer via urethane linkages and wherein the polyether segment comprises at least 70% by weight based on the total weight of the silane modified terpolymer. Also disclosed is a method of forming moisture curable silane modified terpolymer.
US11021561B2	Amine composition useful for making polyurethane foam A catalyst composition for making polyurethane foam, the catalyst composition including a compound having a general formula R1R2R3N, wherein each of R1, R2 and R3 are independently selected from the group consisting of: a compound according to formula (I): wherein n=1 to 5; and R4, R5 and R6 are each independently hydrogen, methyl, ethyl and propyl groups; hydrogen, a C1-C6 alkyl group compound, a C1-C6 cycloalkyl group compound, a C1-C6 alkenyl group compound, a C1-C6 alkynyl group compound, a C1-C6 aryl group compound, and a C1-C6 aralkyl group compound, each group being substituted or unsubstituted; wherein at least one of R1, R2 and R3 is a compound according to formula (I). A polyurethane composition and method for forming a polyurethane foam are also disclosed.
US11021552B2	Toluene free silica supported single-site metallocene catalysts from in-situ supported alumoxane formation in aliphatic solvents The present disclosure provides methods for preparing a catalyst system comprising contacting in an aliphatic solvent at least one support material, at least one hydrocarbyl aluminum compound and at least one non-hydrolytic active oxygen-containing compound to form a supported alumoxane (catalyst system precursor) and contacting the supported alumoxane with at least one catalyst compound having a Group 3 through Group 12 metal atom or lanthanide metal atom. The supported alumoxane may be heated prior to contact with the catalyst compound.
US11021550B2	Method for producing multicomponent copolymer, multicomponent copolymer, rubber composition, and tire To provide a method for producing a multicomponent copolymer with which a multicomponent copolymer having excellent rupture strength can be obtained, and a multicomponent copolymer, a rubber composition and a tire having excellent rupture strength. The method is a method for producing a multicomponent copolymer having a conjugated diene unit, a non-conjugated olefin unit and an aromatic vinyl unit, comprising adding continuously or intermittently continuously a conjugated diene compound into a reactor containing a catalyst and at least one selected from the group consisting of a non-conjugated olefin compound and an aromatic vinyl compound. The multicomponent copolymer is obtained with the production method. The rubber composition comprises the multicomponent copolymer as a rubber component. The tire uses the rubber composition.
US11021547B2	Method of synthesising 6-deoxy-6-amino-β-D-glucopyranoside-containing polymers and their precursors The invention provides an improved method of synthesising derivatives of β-D-glucopyranoside-containing polymers, such as chitin, chitosan, cellulose, amylose, pullulan, curdlan, inulin, guar gum or cyclodextrin. The method includes reacting a polymer of formula (III) with a cyclic imide to form a polymer of formula (I) thereby introducing a nitrogen functionality at the 6-position and providing access to 6-deoxy-6-amino-β-D-glucopyranoside-containing polymers.
US11021546B2	NCC films and products based thereon Provided are NCC-based materials, as superb barrier materials for preventing oxygen and humidity from penetrating therethrough.
US11021544B2	Nanobody dimers linked via C-terminally engineered cysteins The present invention relates to dimers comprising a first polypeptide and a second polypeptide, wherein each of said first and second polypeptide comprises at least one immunoglobulin single variable domain (ISVD) and a C-terminal extension comprising a cysteine moiety (preferably at the C-terminus), wherein said first polypeptide and said second polypeptide are covalently linked via a disulfide bond between the cysteine moiety of said first polypeptide and the cysteine moiety of said second polypeptide, in which the dimer outperformed the benchmark constructs, e.g. cognate multivalent and multispecific constructs, in various assays. The present invention provides methods for making the dimers of the invention.
US11021540B2	Antibodies to programmed cell death protein 1 Antibodies and antigen binding fragments thereof are provided that immunospecifically bind to PD-1, preferably human or mouse PD-1, and induce or promote an immune response that activates immune cell proliferation or activity. Contrary to the existing paradigm that PD-1 exclusively promotes a suppressive immune response, the disclosed antibodies and antigen binding fragments thereof, immunospecifically bind to PD-1 and cause an activating signal to be delivered to the immune cell that activates the immune cell rather than suppressing the immune cell. In one embodiment, the disclosed antibodies and antigen binding fragments thereof specifically bind to PD-1 expressed on immune cells. The binding of the disclosed antibodies and antigen binding fragments thereof to PD-1 on immune cells causes an activating signal to be transmitted into the immune cell, for example a signal that enhances or promotes cytokine production and/or activation of immune cell proliferation. Immune cells that express PD-1, include but are not limited to B and T cells as well as myeloid-derived cells. In one embodiment, the immune cell is a T cell, preferably a CD8+ T cell.
US11021539B2	Drug delivery compositions and uses thereof Provided are drug delivery compositions and devices useful for the treatment and/or prevention of cancer and metastatic tumors. For example, a drug delivery device is provided that comprises a biodegradable scaffold carrying one or more anti-cancer therapeutic agents that activate the innate immune system (e.g., STING agonists) and/or the adaptive immune system (e.g., anti-PD-1 antibodies). The compositions and devices may include a cytokine (e.g., IL-15 superagonist). The drug delivery device can be implanted in the void volume of a resected tumor to prevent tumor regrowth and tumor metastasis. Also provided are methods of making the drug delivery compositions and devices as well as kits containing materials to provide the compositions and devices.
US11021533B2	Human Zika virus antibodies and methods of use therefor The present disclosure is directed to antibodies binding to and neutralizing Zika virus and methods for use thereof.
US11021532B1	Superhuman anti-SARS-CoV-2 antibodies and uses thereof This disclosure provides superhuman antibodies and antigen-binding fragments that can be administered to an individual that is infected or suspected of being infected with a virus. Superhuman antibodies and antigen-binding fragments provided herein can be capable of treating or curing the virus, and which may provide protection against the virus for up to at least several weeks. Superhuman antibodies and antigen-binding fragments provided herein can be used to diagnose a SARS Cov-2 infection.
US11021531B1	Anti-SARS-Cov-2 antibodies derived from 2GHW This disclosure provides antibodies and antigen-binding fragments that are derived from 2ghw and that can be administered to an individual that is infected or suspected of being infected with a virus. Antibodies and antigen-binding fragments provided herein can be capable of treating or curing the virus, and which may provide protection against the virus for up to several weeks. Antibodies and antigen-binding fragments provided herein can be used to diagnose a SARS-Cov-2 infection.
US11021527B2	Transforming growth factor beta receptor type II fusion polypeptides In certain aspects, the present disclosure relates to TβRII fusion polypeptides comprising a heterologous portion and a truncated, ligand-binding portion of the extracellular domain of TβRII polypeptide useful to selectively antagonize a TβRII ligand. The disclosure further provides compositions and methods for use in treating or preventing TGFβ associated disorders.
US11021525B2	Synthetic transcription factor and uses thereof The present invention provides for a synthetic transcription factor (TF) comprising a first peptide capable of binding a target ligand, a second peptide capable of binding a target DNA, and a peptide linker linking the first and second peptides. The present invention also provide for a system for modulating the mutagenesis frequency of a host cell. The host cell has a mutator rate (R) which is inversely proportional to a phenotypic trait (P).
US11021521B2	Pore-modified gram-negative bacteria and uses thereof Mutants of Gram-negative bacteria having outer membranes comprising modified OrbA nanopores absent an N-terminal plug domain are disclosed. The modified OrbA nanopores confer the outer membrane of the bacteria with enhanced permeability. The mutants of Gram-negative bacteria optionally comprise efflux-deficient efflux pumps. The mutants may be used, for example, in a screening method for identifying a compound having an anti-bacterial activity.
US11021518B2	Theta defensin analogs Novel peptide analogs of a θ-defensin have been developed that provide a biphasic effect in treating infection and/or sepsis. These analogs are active at concentrations below those needed to provide a bactericidal or bacteriostatic effect, and function by initially recruiting effector cells of the immune system to address the infective organism followed by regulation of the immune system to down regulate the inflammatory response characteristic of sepsis and septic shock. These novel θ-defensin analogs are protective at concentrations where naturally occurring θ-defensins have no apparent effect, and include a core set of structural and sequence features not found in native θ-defensin.
US11021514B2	Compounds The present technology relates to compounds, kits, compositions, and methods useful for the treatment of numerous pathologies including dementia, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and other neurodegenerative diseases, spinal cord injury, traumatic brain injury, diabetes and metabolic syndrome, defective wound healing, and/or sensorineural hearing and vision loss.
US11021512B2	Method of preparing peptides comprising a lipophilically modified lysine side chain The present invention relates to a method of preparing a lysine side-chain modified peptide by solid phase peptide synthesis.
US11021510B2	Prodrugs of clofarabine A compound useful for treating lymphoma, having the structure of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1 is H or —C(═O)—O—R3, and R2 is H or —C(═O)—O—R4, provided R1 and R2 are not both H; and R3 and R4 are each independently selected from the group consisting of alkyl, alkenyl, alkynyl, aryl, arylalkyl, cycloalkyl, cycloheteroalkyl, and heteroalkyl. In an exemplary compound of formula (I), R1 is —C(═O)—O—CH2—CH3, and R2 is H.
US11021508B2	Use of avermectin derivative for increasing bioavailability and efficacy of macrocyclic lactones The present invention relates to the use of avermectin derivative as a drug for the treatment of parasitic infections. The avermectin derivative is represented by the formula (I) wherein: (i) R1 is chosen from the group constituted of —CH(CH3)2, —CH(CH3)CH2CH3, or cyclohexyl, (ii) X represents —CH2—CH2—, or —CH═CH—, (iii) R2 is chosen from or an OH group, (iv) R3 is OH or NOH, (v) represents a single bond when R3 is OH, or a double bond when R3 is NOH, as an inhibitor of a membrane-bound protein which transports exogenous compounds out of target cells.
US11021505B2	Aqueous extract enriched with small RNAs and compositions comprising such extracts and to their cosmetic uses The invention relates to an aqueous extract enriched with small RNA having a maximum length of 150 nucleotides, from plant material. The invention relates to an aqueous extract of plant material, enriched with small RNAs having a maximum length of 150 nucleotides, which can be obtained by such a method, as well as to the compositions comprising such an extract and to their cosmetic uses for combating the signs of skin aging and for improving the hydration of the skin.
US11021504B2	Functionalization and purification of molecules by reversible group exchange Embodiments of the present disclosure include methods and compositions for functionalizing molecules, such as oligonucleotides, with functional groups, including polyhistidine tags useful in affinity methods. Some embodiments include methods for modifying and purifying complex mixtures of molecules by exchange of functional tags.
US11021503B2	Process for GalNAc oligonucleotide conjugates The invention comprises a process for the preparation of therapeutically valuable GalNAc cluster oligonucleotide conjugates. The process comprises the coupling of an alkali metal salt, earth alkali metal salt or a tetraalkylammonium salt of an oligonucleotide with a GalNAc cluster compound or with a salt thereof and a subsequent purification.
US11021497B2	Compositions and methods for synthesis of phosphorylated molecules The invention provides compositions and methods for synthesis of phosphorylated organic compounds, including nucleoside triphosphates.
US11021484B2	Compound including nitrogen and organic electroluminescence device including the same Provided are a compound including nitrogen, represented by Formula 1, and an organic electroluminescence device including the same. In Formula 1, A1 to A10 are each independently CR3 or N. The organic electroluminescence device may include a first electrode, a second electrode which is opposite to the first electrode, and a plurality of organic layers disposed between the first electrode and the second electrode, wherein the plurality of organic layers include an emission layer, and at least one organic layer among the organic layers includes the compound including nitrogen.
US11021483B2	Crystalline of camphorsulfonic acid salt of rucaparib and method of preparing of tricyclic compounds, rucaparib and crystalline of camphorsulfonic acid salt of rucaparib A method of preparing a tricyclic compound of formula (I), comprising the step of converting a compound of formula (II) into a compound of formula (III); and hydrogenating the compound of formula (III) in the presence of hydrogenation catalyst and hydrogen to form the tricyclic compound of formula (I); wherein R1 is H or a C1-3 alkyl group; and R2 is H, a halogen element or a C1-3 alkyl group.
US11021480B2	Inhibiting (α-V)(β-6) integrin Disclosed are small molecule inhibitors of αvβ6 integrin, and methods of using them to treat a number of diseases and conditions.
US11021479B2	Pyridoquinazoline derivatives useful as protein kinase inhibitors The present invention relates to novel 11-oxo-11H-pyrido[2,1-b]quinazoline-6-carboxamide derivatives as potent inhibitors of protein kinase, to pharmaceutical compositions containing them and to the use of said compounds for the manufacture of a drug for the treatment of diseases or pathological diseases that can be improved by inhibiting protein kinase.
US11021478B2	Indolizine derivatives and their application in medicine This invention relates to indolizine derivatives and their use in medicine. In particular, the present invention discloses novel substituted indolizine derivatives of formula I, or an isotopically labeled compound thereof, or an optical isomer thereof, a geometric isomer thereof, a tautomer thereof or a mixture of various isomers, or a pharmaceutically acceptable salt thereof, or a prodrug thereof. The invention also relates to the use of these compounds in medicine.
US11021476B2	Pyrroloquinoline quinone monosodium and method for producing the same, and composition comprising the same The present invention provides pyrroloquinoline quinone monosodium having a structure represented by the following formula (1).
US11021474B2	N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)-phenyl]-acetamide free base hemihydrate, methods of manufacture and uses thereof The present invention relates to the field of anti-viral active agents, particularly the free base hemihydrate form of N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)-phenyl]-acetamide as well as methods for the manufacture thereof. The present invention relates also to the use of the above compound in the treatment of human herpes virus infections and in the preparation of pharmaceuticals comprising said compound.
US11021473B2	Organic molecules for use in organic optoelectronic devices An organic molecule is disclosed comprising: a first chemical moiety with a structure of formula I, and two second chemical moieties, each at each occurrence independently from another, with a structure of formula II, wherein the first chemical moiety is linked to each of the two second chemical moieties via a single bond.
US11021471B2	Antibacterial compounds Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
US11021469B2	Indoline sulfonamide inhibitors of DapE and NDM-1 and use of the same Indoline sulfonamide compounds that can inhibit DapE and/or bacterial metallo-β-lactamases (MBLs), such as NDM-1, are disclosed. Also disclosed are methods of treating an individual suffering from a bacterial infection using the indoline sulfonamide compounds disclosed herein.
US11021467B2	Phosphatidylinositol 3-kinase inhibitors The present application provides the compounds of formula (J), or pharmaceutically acceptable salts, isomers, tautomer, or a mixture thereof, wherein n, W, A′, B′, R1, R2, and R3 are described herein. The compounds are inhibitors to the activities of phosphatidylinositol 3-kinase (PI3K) and are useful for treating conditions mediated by one or more PI3K isoforms. The present application further provides pharmaceutical compositions that include a compound of formula (I), or pharmaceutically acceptable salts, isomers, tautomer, or mixture thereof, and methods of using these compounds and compositions for treating conditions mediated by one or more PI3K isoforms.
US11021466B2	IRE1 small molecule inhibitors Provided herein are small molecule inhibitors for the targeting or IRE1 protein family members. Binding may be direct or indirect. Further provided herein are methods of using IRE1 small molecule inhibitors for use in treating or ameliorating cancer in a subject. Moreover, IRE1 small molecule inhibitors described herein are for the treatment of cancer, where the cancer is a solid or hematologic cancer.
US11021465B2	DNA-PK inhibitors The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
US11021455B2	Brominated furanone derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient The present invention relates to a novel brominated furanone derivative, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient, wherein the novel brominated furanone derivative or a pharmaceutically acceptable 5 salt thereof according to the present invention exhibits a quorum sensing inhibitory activity of bacteria and also can effectively inhibit the formation of biofilm of bacteria, and thus can be used as a pharmaceutical composition containing the same as an active ingredient, thereby having an effect of being useful, 10 for example, for periodontal diseases such as gingivitis and periodontitis, oral diseases, and the like.
US11021451B2	Contrast agents The present invention relates to new class of functionalized macrocycles capable of chelating paramagnetic metal ions, their chelated complexes with metal ions and the use thereof as contrast agents, particularly suitable for Magnetic Resonance Imaging (MRI) analysis.
US11021450B2	PSMA targeted fluorescent agents for image guided surgery Compositions and methods for visualizing tissue under illumination with near-infrared radiation, including compounds comprising near-infrared, closed chain, sulfo-cyanine dyes and prostate specific membrane antigen ligands are disclosed.
US11021447B2	Fluorescent halogen bonding arylethynyl scaffolds for anion recognition A compound, or a protonate or salt thereof, of formula I: wherein Y is aryl, substituted aryl, heteroaryl, or substituted heteroaryl; n is 1 or 2; each R10 is independently alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, aryl, substituted aryl, cyano, hydroxyl, carbonylamino, aminocarbonyl, acyl, sulfonyl, or substituted sulfonyl; a is 0 to 4; is an aryl or heteroaryl ring; and each R is independently halogen, carbonylamino, sulfonamide, carboxylic acid or hydrogen, provided at least one R is a halogen; and provided that if Y is are not respectively.
US11021443B2	Charged ion channel blockers and methods for use The invention provides compounds, compositions, methods, and kits for the treatment of pain, itch, and neurogenic inflammation.
US11021442B2	Process for the preparation of freeze-dried 2-[(3-aminopropyl)amino] ethanethiol formulation A process for the preparation of freeze-dried 2-[(3-aminopropyl)amino]ethanethiol including the following steps: a) the reaction of a solution of amifostine with a strong acid, to obtain a solution of 2-[(3-aminopropyl)amino]ethanethiol, and b) the freeze-drying of the solution of 2-[(3-aminopropyl)amino]ethanethiol, with or without addition of excipients.
US11021432B2	System for continuously purifying reaction product of esterification The present disclosure relates to a system and a method for continuously purifying a reaction product of esterification, where the system includes a neutralizer, a distiller, and a product purifier. Through the present system and the method, it is possible to perform a continuous purification process efficiently, and to reduce lower alcohol wastewater generated during purification.
US11021429B1	Methods for producing a methanol precursor, methanol, and a methyl ester from methane in high purities A method for producing a methanol precursor, methyl trifluoroacetate, having high-purity includes the steps of (a) preparing methyl bisulfate by mixing a catalyst with an acid solution comprising a sulfur-containing acid to provide a first mixture and supplying methane gas to the first mixture to prepare the methyl bisulfate; and (b) preparing methyl trifluoroacetate (CF3CO2CH3) by adding trifluoroacetic acid (CF3CO2H) to the first mixture including the methyl bisulfate to provide a second mixture and distilling the second mixture under heating to prepare, separate and purify the methyl trifluoroacetate (CF3CO2CH3). Methanol may be produced by adding water to the methyl trifluoroacetate (CF3CO2CH3). A methyl ester represented by Formula 2 below may be produced by adding a carboxylic acid represented by Formula 1 below to the methyl trifluoroacetate (CF3CO2CH3): R1CO2H (1), where R1 is selected from C1-C10 alkyl groups, R1CO2CH3 (2), where R1 is as defined in Formula 1.
US11021427B2	Pd(II)-catalyzed enantioselective C—H arylation of free carboxylic acids The invention includes procedures for stereoselective β-acylation of carboxylic acids having a β-carbon atom. For example, stereoselective acylation procedures include the following reactions: (I)
US11021419B2	Dehydrogenation catalysts and methods for preparing and using them This disclosure relates to catalysts comprising gallium, cerium, and a mixed oxide support useful in the dehydrogenation of hydrocarbons, to methods for making such catalysts, and to methods for dehydrogenating hydrocarbons with such catalysts. For example, in one embodiment, a catalyst composition includes gallium oxide, present in the composition in an amount within the range of about 0.1 wt. % to about 30 wt. %, cerium oxide, present in the composition in an amount within the range of about 0.1 wt. % to about 15 wt. %, a promoter, M1, selected from Pt, Ir, La, or a mixture thereof, present in the composition in an amount within the range of about 0.005 wt. % to about 4 wt. %, a promoter, M2, selected from the group 1 elements (e.g., Li, Na, K, Cs), present in the composition in an amount within the range of about 0.05 wt. % to about 3 wt. %, and a support, S1, selected from alumina, silica, zirconia, titania, or a mixture thereof, present in the composition in an amount within the range of about 60 wt. % to about 99 wt. %.
US11021417B2	Process for oligomerization with dry handling of a catalyst before charging to the reactor A process is useful for the oligomerization of short-chain olefins in the presence of a catalyst, wherein the catalyst is kept in a dry atmosphere prior to being used in the process.
US11021413B2	Benzylpropargylether as nitrification inhibitors The present invention relates to the use of compounds of formula (I) for reducing nitrification and to compositions comprising the compounds of formula (I) and to agricultural mixtures comprising at least one compound of formula (I) and at least one fertilizer. Furthermore, the present invention relates to a method for reducing nitrification comprising treating a plant growing on soil or soil substituents and/or the locus or soil or soil substituents where the plant is growing or is intended to grow with a compound of formula (I) or a composition comprising a compound of formula (I).
US11021412B2	Fertilizer comprising bioavailable Si and method for production thereof The present invention relates to a humic substance based Si-fertilizer product having storage-stable, bio-available Si, which is produced by forming a mixture of, 45-95% by weight of a humic acid-containing raw material, 5-50% by weight of amorphous silica, and 0.5-10 % by weight of an alkali, all amounts based on the total weight of the dry components, incubated in an aqueous medium, and optionally dried and granulated, wherein the bio-available silicon is in the form of water-soluble chelates of monosilicic acid-humate compounds. The invention also relates to a method of producing humic substance based Si-fertilizer, a method for increasing the uptake of silicon in plants and use of the humic substance based Si-fertilizer.
US11021410B2	Layer-wise agglomerated urea granules The present disclosure generally relates to layer-wise agglomerated controlled release granular urea composition and methods of making and using the layer-wise agglomerated controlled release granular urea composition. In a particular composition, the water-soluble plant nutrient comprises urea, the binding material for the core comprises corn starch, the hydrogel for the coating layer comprises corn starch hydrogel, the core has a thickness of 2.5-3.5 mm and a closed porosity of 0.05-3%, and the coating layer has a thickness of 1.35-1.5 mm and a closed porosity of 0.1-5%.
US11021407B2	Copper/ceramic composite The invention relates to a copper/ceramic composite comprising—a ceramic substrate which contains aluminum oxide, —a coating which lies on the ceramic substrate and which is made of copper or a copper alloy, wherein the copper or the copper alloy has a particle size number distribution with a median value d50, an arithmetic mean value darith, and a symmetry value S(Cu)=d50/darith; the aluminum oxide has a particle size number distribution with a median value d50, an arithmetic mean value darith, and a symmetry value S(Al2O3)=d50/darith; and S(Al2O3) and S(Cu) satisfy the following condition: 0.7≤S(Al2O3)/S(Cu)≤1.4.
US11021405B2	Moulded insulation bodies Moulded insulation bodies, processes for the production thereof and use thereof consisting essentially of ceramic material comprising SiO2 fibers and Al2O3 fibers which has been produced using Al2O3 sol as a binder and kilned at a temperature of above 800° C. for insulation of the ends of cracking tubes of a tubular reactor for performing a steam reforming process for generating synthesis gas which project out of the reactor heating space.
US11021403B2	Method for forming a temperature compensated dielectric material Disclosed are embodiments of tungsten bronze crystal structures that can have both a high dielectric constant and low temperature coefficient, making them advantageous for applications that experience temperature changes and gradients. In particular, tantalum can be substituted into the crystal structure to improve properties. Embodiments of the material can be useful for radiofrequency applications such as resonators and antennas.
US11021402B2	Method of preparing carbon fiber reinforced carbon-silicon carbide composite part A method of preparing a C/C-SiC composite part, including: preparing, using a solvent evaporation process, carbon fiber composite powders coated with a phenol resin; according to a three-dimensional model of a to-be-prepared part, forming a green part corresponding to the to-be-prepared part using the carbon fiber composite powders and a 3D printing technology; densifying the green part to yield a C/C porous body having a density of 0.7 to 1.1 g/cm3 and an open porosity of 30 to 50%; and siliconizing the C/C porous body under vacuum, removing excess silicon to yield a primary carbon fiber reinforced carbon-silicon carbide (C/C-SiC) body, densifying the primary C/C-SiC body, to obtain a final C/C-SiC composite part.
US11021401B2	Zirconia sintered body and method for manufacturing the same Provided are a zirconia sintered body capable of being widely used as a dental material, in particular, a zirconia sintered body capable of being applied to both a dental material for a back tooth and a dental material for a front tooth and a simple and easy method for manufacturing the zirconia sintered body.The method for manufacturing a zirconia sintered body includes a molding step of molding a powder composition that has an yttria content of more than 3% by mole and 5.2% by mole or less and that contains a first zirconia powder having an yttria content of 2% by mole or more and 4% by mole or less and a second zirconia powder having an yttria content of more than 4% by mole and 6% by mole or less to obtain a green body, and a sintering step of sintering the green body to obtain a sintered body.
US11021400B2	Ultra-high dielectric constant garnet Disclosed are embodiments of synthetic garnet materials for use in radiofrequency applications. In some embodiments, increased amounts of bismuth can be added into specific sites in the crystal structure of the synthetic garnet in order to boost certain properties, such as the dielectric constant and magnetization. Accordingly, embodiments of the disclosed materials can be used in high frequency applications, such as in base station antennas.
US11021399B2	Self-consolidating geopolymer compositions and methods for making same Self-consolidating geopolymer compositions utilizing fly ash and inorganic mineral including alkaline earth metal oxide as cementitious reactive components and include cement set retarder. The alkaline earth metal oxide is preferably calcium oxide (also known as lime or quicklime) and/or magnesium oxide. The inorganic minerals including alkaline earth metal oxide have an alkaline earth metal oxide content preferably greater than 50 wt. %, more preferably greater than 60 wt. %, even more preferably greater than 70 wt. %, and most preferably greater than 80 wt. %, for example greater than 90 wt. %. The cementitious reactive powder may optionally also include one or more aluminous cements and one or more source of calcium sulfates. The cementitious reactive powders are activated with an alkali metal chemical activator selected from alkali metal salt and/or alkali metal base. Methods for making the compositions are also disclosed.
US11021397B2	Bitumen which is solid at ambient temperature Bitumen which is solid at ambient temperature, in the form of granules including a core made of a first bituminous material and a coating layer made of a second bituminous material, in which: the first bituminous material includes at least one bitumen base and the second bituminous material includes: at least one bitumen base and at least one chemical additive chosen from: an organic compound, a viscosifying compound, a paraffin, a polyphosphoric acid and mixtures thereof; or at least one pitch having a ring-and-ball softening point (RBSP) greater than or equal to 80° C., it being understood that the RBSP is measured according to the EN 1427 standard; or a mixture of these materials.
US11021396B2	Modified nonvolatile cold asphalt binder and recycled asphalt mixture using thereof A nonvolatile cold modified asphalt binder and a nonvolatile cold recycled asphalt mixture using the same are manufactured by optimally mixing a petroleum asphalt, a native asphalt, a polymer modifier, process oil, and an adhesive strength enhancer. The nonvolatile cold modified asphalt binder includes at least one petroleum asphalt selected from a straight asphalt or a blown asphalt; at least one native asphalt selected from gilsonite, glance pitch, and grahamite; a rubber-modified-compound (RMC) polymer modifier which is a vinyl aromatic hydrocarbon-conjugated diene block copolymer including at least one of a styrene-butadiene block copolymer (SBS), a styrene-isoprene block copolymer (SIS), and a styrene-ethylene-butylene block copolymer (SEBS); at least one process oil selected from paraffin oil, naphthenic oil, aromatic oil, natural oil, and mineral oil; and at least one adhesive strength enhancer selected from rosin esters, modified acryls, modified silicones, polyvinyl esters, and silicone resins.
US11021389B2	Supporting glass substrate A supporting glass substrate has a ratio of a Young's modulus (GPa) to a density (g/cm3) that is 37.0 (GPa·cm3/g) or more and the ratio has a value larger than a ratio calculation value, the ratio calculation value being a ratio of a Young's modulus (GPa) calculated from a composition to a density (g/cm3). The ratio calculation value is represented by the following expression: α=2·Σ{(Vi·Gi)/Mi·Xi}, where, in the expression, Vi is a filling parameter of a metal oxide contained in the supporting glass substrate, Gi is a dissociation energy of a metal oxide contained in the supporting glass substrate, Mi is a molecular weight of a metal oxide contained in the supporting glass substrate, and Xi is a molar ratio of a metal oxide contained in the supporting glass substrate.
US11021380B1	Modular wastewater treatment system configured for compact shipping A module for a wastewater treatment system, for use when buried in permeable media such as sand or soil, includes a central distribution unit and a multiplicity of treatment fins in flow communication therewith. Within each fin is a lengthwise-running perforated pipe. In one kind of assembly, a treatment system module comprises a central housing has attached fins which are wrapped in spiral fashion around the central distribution unit when in a compact shipping container. In another assembly, the fins are attached to a central membrane and shipped in a container while folded, detached from the central distribution unit; and the distribution unit may be comprised of separate nested half units to be joined at the point of use. When take to a wastewater treatment site, the packed components are removed from the container and arranged for use.
US11021378B2	Sterile and/or purified fluid and/or solution delivery system A system for on-demand delivery of a sterile fluid includes a housing. At least one fluid reservoir is associated with the housing and configured to hold a fluid. A sterilization and/or purification mechanism is in fluid communication with the at least one fluid reservoir. The sterilization and/or purification mechanism is configured to sterilize the fluid. A dispensing mechanism is in fluid communication with the sterilization mechanism and configured to dispense the sterile fluid. A controller is associated with one or more of the housing, the at least one fluid reservoir, the sterilization and/or purification mechanism, and the dispensing mechanism. The controller being configured to modulate at least one operating characteristic of the system. The system is configured to deliver the sterile and/or purified fluid immediately after a request is made.
US11021377B1	Submerged reverse osmosis system and method for operating the same A system and method of operating the same includes a membrane chamber comprising a membrane, an inlet, a concentrate outlet and a permeate outlet. The membrane chamber is located in a body of water at a predetermined depth. A turbocharger is disposed at about the predetermined depth and includes a pump portion coupled to the inlet of the membrane chamber and a turbine portion coupled to the concentrate outlet. A pump communicates pressurizing feed fluid and communicates the feed fluid to the turbine portion of the turbocharger though a feed pipe. A permeate pipe extends from the permeate outlet to about the surface of at the body of water.
US11021375B2	Methods for producing and using alkaline aqueous ferric iron solutions Methods for removing reduced sulfur compounds, such as hydrogen sulfide, from fluids employing a ferric iron salt that exhibits unusually high solubility in aqueous, alkaline solutions and has strong affinity for capture and oxidation of reduced sulfur compounds. Alkaline aqueous ferric iron salt and solutions thereof useful for removing reduced sulfur compounds from fluids and various methods of production of such salts and solutions. In addition, methods of regenerating the alkaline aqueous ferric iron salt solutions after capture of hydrogen sulfide or other reduced sulfur compounds, generally by exposure to oxygen in air. The alkali metal carbonate salt preferably comprises potassium carbonate and/or potassium bicarbonate. The alkaline aqueous ferric iron salt solutions generally comprise ferric ions, potassium ions, carbonate ions, and bicarbonate ions, optionally with one or more organic additives. In addition, aqueous-soluble, ferric iron salts and ferric iron containing solids prepared by removal of aqueous medium from solutions herein.
US11021374B2	PCC with reduced portlandite content The present invention is directed to a process for producing an aqueous suspension of precipitated calcium carbonate, wherein a milk of lime is prepared by mixing water, a calcium oxide containing material, and a precipitation enhancer, and subsequently, the milk of lime is carbonated to form an aqueous suspension of precipitated calcium carbonate.
US11021368B2	Carbon nanotube sheet structure and method for its making A carbon nanotube (CNT) sheet containing CNTs having a median length of at least 0.05 mm and an aspect ratio of at least 2,500; L arranged b a randomly oriented, uniformly distributed pattern, and having a basis weight of at least 1 gsm and a relative density of less than 1.0. The CNT sheet is manufactured by applying a CNT suspension in a continuous pool over a filter material to a depth sufficient to prevent puddling of the CNT suspension upon the surface of the •filter material, and drawing the dispersing liquid through the filter material to provide a uniform CNT dispersion and form the CNT sheet. The CNT sheet is useful in making CNT composite laminates and structures having utility for electromagnetic wave absorption, lightning strike dissipation. EMI shielding, thermal interface pads, energy storage, and heat dissipation.
US11021367B2	Lithium composite phosphate-based compound and preparation method therefor Provided is a porous lithium composite phosphate-based compound containing lithium and having open pores formed in primary particles. As the open pores are formed in the primary particles themselves, a contact area between an electrolyte and the lithium composite phosphate-based compound is maximized, and low conductivity is compensated for, such that a diffusion rate of lithium ions is remarkably increased, and when the lithium composite phosphate-based compound is used as an active material of a secondary battery, the secondary battery may be charged and discharged at a high speed. Additionally, there are advantages in that an electrode density may be significantly increased in addition to the increase in the diffusion rate of the lithium ions, and charge and discharge cycle characteristics may be significantly stable.
US11021365B2	Steam reforming process Steam reforming system having a steam cracker and a steam reformer. The steam cracker includes a steam cracking unit to steam crack a feed stream to produce a stream comprising hydrogen, methane and C2+ hydrocarbons; a heat exchanger for cooling the steam cracking product stream; a separation unit for separating the cooled steam cracking product stream into a gas stream including hydrogen and methane and a liquid stream including methane and C2+ hydrocarbons, a demethanizer which is fed the liquid stream producing a third stream containing at least 95% methane and a fourth stream comprising C2+ hydrocarbons. The steam reformer includes a feed preheater which is fed the third stream and steam to provide a preheated stream and a steam reforming unit arranged for heating the preheated stream to at least 800° C. to steam reforming the heated stream and obtain a product stream containing hydrogen and CO2.
US11021362B1	Fuel nozzle retainer kit A fuel nozzle retainer kit includes a first retainer that is attachable to a fuel tank that has a skirt thereon. The first retainer extends over a fill port on the fuel tank. Additionally, the first retainer has elastomeric properties to engage and thus retain a fuel nozzle in the fuel port. A second retainer is attachable to a fuel tank that does not have a skirt thereon. The second retainer has a first portion that is mountable around a fill port of the fuel tank that does not have a skirt. The second retainer has a second portion which is pivotally coupled to the first portion. Additionally, the second portion is positionable to engage a fuel nozzle inserted into the fill port to retain the fuel nozzle in the fill port.
US11021356B2	Bottle closing device for placing press-fit closures, such as crown corks, crown caps, and similar closures, on bottles or similar containers A bottle closing device for placing press-fit closures, such as crown corks, crown caps, and similar closures, on bottles or similar containers. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. § 1.72(b). As stated in 37 C.F.R. § 1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading “Abstract of the Disclosure.” The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner.
US11021355B2	Pry bar assembly A pry bar assembly includes a plate that is elongated and has a first end, a second end, a first lateral edge, a second lateral edge, an upper surface and a lower surface. The plate includes a claw section, a chisel section and a middle section positioned therebetween. The claw section includes the first end and a rounded heel. The claw section includes a first portion and a second portion. The first portion is attached to the middle section and curves upwardly and away from the middle section in a semi-cylindrical shape to form the rounded heel. The second portion extends downwardly from the first portion. The chisel section is angled upwardly from the middle section. The upper surface has an elongated crest therein that is spaced from the first and second lateral edges and extends along a length of the middle section and into the chisel section.
US11021354B2	Industrial truck having a hydraulic fluid tank An industrial truck comprises a support having a plurality of receptacles and a hydraulic fluid tank comprising a plurality of feet engaged with a bottom surface of the hydraulic fluid tank. Each of the plurality of feet is configured to be received by one of the plurality of receptacles.
US11021351B2	Lifting device for pallet goods Lifting device for pallet goods for loading and unloading of a transport pallet such as a standard pallet, for example a euro pallet. The lifting device comprises a support frame, a tine assembly liftable mounted to the support frame of at least two, preferably four, tines having a parallel direction of extension for lifting and receiving the transport goods from the transport pallet and/or for depositing the transport goods onto the transport pallet. A tine spacing of two tines is adapted to a gap spacing of two longitudinal gaps and at least two tines are form-fitted with regard to the at least two longitudinal gaps such that they can access the longitudinal gaps in the longitudinal direction.
US11021350B2	Ramps for low-profile vehicles A ramp for assisting the loading of a vehicle onto a rollback car carrier or the like. The ramp including a front ramp assembly, a middle ramp assembly rotatably connected to the front ramp assembly, a rear ramp assembly rotatably connected to the middle ramp assembly, and a trailer abutment section positioned adjacent to the rear ramp assembly.
US11021348B2	Automated cargo transfer system An automated cargo transfer system is used, in conjunction with a crane, to load cargo onto, and unload cargo from, the deck of a watercraft. An example automated cargo transfer system comprises: a dynamic positioning system installed on the watercraft; a crane hook system installed on the crane; a crane automation system configured to automate the operation of the crane; and a load plan comprising: data that identifies all cargo being transported by the watercraft, data used by the dynamic positioning system to actively position and orient the watercraft during loading and unloading of the watercraft, and data used by the crane hook system to actively position and orient it's hook mechanism during loading and unloading of the watercraft. The automated cargo transfer system is configured to actively track the location of the watercraft, the hook mechanism of the crane hook system, and cargo. The automated cargo transfer system is also configured to actively position and orient the watercraft and the hook mechanism of the crane hook system based on the location and weight of cargo being loaded onto, and unloaded from, the watercraft.
US11021347B2	Materials management systems and methods A material management method comprises receiving, via a processor, data relating to work activities and material flows from one or more sensors; generating, via the processor, safety and productivity information based on the data relating to work activities and material flows; comparing, via the processor, the generated safety and productivity information with existing project plans and schedules of the work activities and material flows; determining, via the processor, a present state and relative progress of the project plans and schedules of work; and generating, via the processor, updated project plans and schedules of work. The material can be a load and the method can comprise controlling rotation of a suspended load by attaching two or more gyroscopic modules in communication with the processor directly or indirectly to the suspended load and independently controlling the two or more gyroscopic modules via the processor to control the rotation of the suspended load.
US11021344B2	Depth sensor and method of intent deduction for an elevator system An elevator system is provided and includes a sensor assembly and a controller. The sensor assembly is disposable in or proximate to an elevator lobby and is configured to deduce an intent of an individual in the elevator lobby to board one of one or more elevators and to issue a call signal in response to deducing the intent of the individual to board the one of the elevators. The controller is configured to receive the call signal issued by the sensor assembly and to assign one or more of the elevators to serve the call signal at the elevator lobby.
US11021343B2	Container for thread distribution and needle storage A container is described for storing various tools and items for sewing in an organized manner and facilitating the process of sewing (e.g., for sewn in hair extensions) for example, by distributing thread. In an example embodiment, the introduced container comprises a housing within which one or more spools of thread can be stored on one or more spindles. The housing can be enclosed by a container top that includes a threading hole through which thread from the one or more spools can be extracted from the interior of the housing, while in use. Further, the container top can include a pin and/or needle holder such as a pin cushion. The container may include additional features such as a bracket for holding a pair of scissors and a drawer for stowing extra thread and/or needles.
US11021340B2	Sheet stacking device including turnable anti-slip stopper and post-processing device A sheet stacking device includes a conveyance part and a stopper. The conveyance part includes a tray and a conveyance member. On the tray, sheet stacks are stacked. The conveyance member conveys the sheet stack on the tray. The stopper is located on a downstream side of the tray and prevents the sheet stack from falling from the tray. The stopper has a main plate and an anti-slip member. The main plate is inclined upward. The main plate has a contact face coming into contact with the sheet stack and a bent face bent downward from a downstream side tip end of the contact face. The anti-slip member is provided from a downstream side end portion of the contact face to the bent face. A frictional coefficient between the anti-slip member and the sheet stack is larger than a frictional coefficient between the sheet stack and the contact face.
US11021335B2	Drive module and linear transport system A drive module for a linear transport system comprises a housing and a stator, wherein a conveying device of the linear transport system with a magnet arrangement can be arranged on the housing. The stator is arranged in the housing, wherein the stator comprises at least one coil arrangement having at least one coil with at least one stator tooth. The coil arrangement is designed to switchably provide a magnetic traveling field, wherein the magnetic traveling field exits from the coil arrangement at the end faces and passes through the housing shells in order to enter into operative connection with the magnet arrangement of the conveying device of the linear transport system on the outer side of the housing for the purpose of forming a magnetic coupling.
US11021334B2	Conveying and sorting apparatus A conveying and sorting apparatus has tilting motors which switch tilting conveyor units which are supported so as to be able to swing about a support shaft that is parallel with the conveying direction, between a horizontal conveying orientation and a tilted orientation; and a conveyor driving motor which drives the conveying conveyors and that are provided to the tilting conveyor units. The support shaft has a single interlocking transmission shaft having a length which covers the entire area of the plurality of tilting conveyor units. The conveying conveyors of each tilting conveyor unit are interconnected by the interlocking transmission shaft. One conveyor driving motor is provided for the plurality of tilting conveyor units supported by the interlocking transmission shaft. This single conveyor driving motor drives the conveying conveyors via the interlocking transmission shaft.
US11021332B2	Shoe outsole dispensing apparatus A shoe outsole dispensing apparatus having a dispenser located above the conveyor carrying adhesive-coated shoe outsoles that are classified into left outsoles and right outsoles and that are dispensed such that the left outsoles to a first side of the conveyor and the right outsoles to a second side of the conveyor is provided. A controller controls the operation of the dispenser. As a result of the outsoles coated with adhesive being automatically classified as left and right outsoles by the dispenser, and the outsoles are dispensed on opposite sides of the conveyor carrying the outsoles, this has the result that productivity of assembling shoes greatly increased as a result of the ability to dispose outsoles very quickly compared to the prior art operation of manually sorting the outsoles, and also the occurrence of shoe defects due to manual errors may be prevented, thus enhancing shoe quality.
US11021331B2	Lubrication system for roller chain, and conveying assembly equipped with such lubrication system A lubrication system for a roller chain. The lubrication system provides a lubricant reservoir, at least one piston pump, and synchronization means. The synchronization means has engaging means dedicated to mechanically mesh with roller chain in motion, and actuating means fastened in motion with the synchronization means the actuating means being in constant mechanical cooperation with a piston pump.
US11021327B2	Telescopic material conveyer apparatus A telescopic material conveyer apparatus has a main boom assembly reinforced by a steel saddle frame connected to a turn table and a lift mechanism, an extension boom assembly adapted by two or more roller assemblies and connecting hardware to travel mechanically within the main boom assembly and to extend therefrom, one or more connected drive motors, a conveyer belt supported by frame architecture and a pulley and drive chain system, at least one hydraulic motor having operative connection to the turntable, lift mechanism and to a belt drive drum, at least one hydraulic valve connected inline in the hydraulic line controlling the belt drive motor, the valve electronically operable via input received from a load sensor integrated within or to the lift mechanism, a programmable load threshold determining open and close operation states of the valve and directing run and stop state operations of the conveyer belt.
US11021325B2	Rescue device A rescue device comprising a closed loop element made of a flexible material and first and second slidable elements mounted to the closed loop element so as to be slidable therealong while frictionally engaging the closed loop element. The first and second slidable elements each pinch the closed loop element against itself to define a pair of opposed end loop portions and an intermediate loop portion extending therebetween, the intermediate loop portion extending between the first and second slidable elements and each of the end loop portions extending from a respective one of the first and second slidable elements opposed to the intermediate loop portion.
US11021320B2	Foldable double-deck frame container The present invention discloses a foldable double-deck frame container, which comprises a first and second end rails parallel with each other and a first corner post, the first corner post is located at an end of the frame container, the first and second end rails are located between two of the first corner posts, and the second end rail is located above the first end rail, the frame container further comprises a second corner post rotatably connected with the top end of the first corner post so that the second corner post is movable between an vertical position and a folded position. The foldable double-deck frame container according to the present invention has a first corner post and a second corner post, and the second corner post is foldable so as to be folded during the backhaul process from being damaged. Such a frame container has a simpler configuration, lower cost of manufacture, convenience of recovery and a broad range of application.
US11021317B2	Packaging device for a windscreen wiper comprising a curved blade and an integrated flexible structure A packaging device for a windscreen wiper blade has a housing configured to receive the blade, having a first support surface configured to contact a portion of an upper part of the blade, a second support surface configured to contact a first portion of a lower part of the blade, a third support surface configured to contact a second portion of the lower part of the blade, a centering means, and a hooking means for hanging the packaging device vertically. The centering means blocks the blade at the center of the housing when the packaging device is hung. The first support surface extends opposite an area situated between the second support surface and the third support surface, and the first, second, and third support surfaces together immobilize the blade inside the housing in a position that is at least partially straightened out relative to a resting position of the blade.
US11021315B2	Spray cap system A spray cap system is described that can enable a user to more consistently and accurately dispense and work with the contents of a spray can. The system includes a spray cap, spray button, spray nozzle, implement holder, and an implement (such as a brush, a foam pad applicator, or a sponge). By using the spray cap system, a user may achieve a more optimal discharge pattern of the contents of the can with a more efficient and optimal coverage of a surface. In addition, the user may utilize the implement while it is attached to the spray cap or remove the implement to use the implement independently. The spray cap system provides versatility to a user by enabling the user to spray the contents of the spray can regardless of whether the implement is attached to the spray cap.
US11021311B2	Vacuum container for storage of air sensitive materials A storage container apparatus is provided for storing air sensitive materials under a vacuum. The apparatus includes having a cylindrical container body opened at its upper end and a cap apparatus with an integral air pump to evacuate air from the container body to create a vacuum. The cap apparatus comprises an inner cap with a one-way air valve and an outer cap. The outer cap is slidably nested over the inner cap and confines a central air chamber which fills with air from the container body through the one-way air valve when pulled upwardly in a reciprocating motion. In the down stroke the air is evacuated from the air chamber through vents. The outer cap may include locking mechanism and vacuum level indicator. The outer cap may include an activated carbon cloth insert that suppresses odors from the material stored in the container.
US11021310B2	System supporting filling and handling bulk bag apparatus containing torrefied materials A container includes a multilayered composite film combination forming a bag defining a product fill opening. The multilayered composite film combination includes first and second polymer film inner and outer layers each having vacuum holding properties, and a third polymer film disposed between the first and second polymer films. The third polymer film has oxygen barrier properties. Product is packed into the container by coupling a fill spout of the container with a fill tube of a product filling apparatus, and oxygen is drawn from an inner cavity of the container. Fluidized product entrained in nitrogen and/or carbon dioxide gas is flowed through the fill spout of the container, and nitrogen is added into the inner cavity through the fill spout of the container. The fill spout of the container is sealed while a negative pressure is drawn within the inner cavity thereby immobilizing the product within the container.
US11021309B2	Cushion member, package body A cushion member includes a tubular portion and an abutting portion. The tubular portion has, in its inside, a hollow that extends in a second direction perpendicular to a first direction that is a longitudinal direction of a storage portion. The tubular portion can be elastically deformed by an external force in the first direction. The abutting portion abuts on, in the first direction, a portion of the cover portion other than the lid. An evasive cut portion is formed at a portion of the tubular portion that faces the lid of the cover portion in the first direction, the evasive cut portion being a cut that is cut into from an end of the tubular portion in the second direction.
US11021303B2	Container closure with ribs formed in sealing compound A closure for a container. The closure comprises an end panel, a sidewall depending from the end panel and having an inwardly directed curl, and a sealing compound extending down the inner surface of the sidewall. A plurality of ribs are formed in the sealing compound, spaced apart around the circumference of the sidewall, each rib extending down the sidewall and projecting radially inwardly.
US11021300B2	Flexible packaging with internal release The invention comprises a package for reactive materials comprising a panel defining a first end, a second end opposite the first end, and at least two side edges. The panel comprises at least one film layer, an adhesive adjacent the film layer, wherein the adhesive is pattern applied such that it is disposed within an interior region of the film layer and wherein a perimeter of the film layer is adhesive-free adjacent each of the first end, second end, and side edges, and a release liner comprising a substrate layer and a cured silicone layer. The release liner is adhered to the film layer via the adhesive, the substrate layer of the release liner is disposed adjacent the film layer, and a perimeter of the release liner is smaller than the perimeter of the film structure. In an embodiment, the panel comprises a tubular body and the side edges are sealed together to form a fin seal, the first end is sealed closed to form an end seal, and the second end is sealed closed to form an end seal.
US11021296B2	Collapsible food container The present specification discloses a collapsible food container. The container includes a wall portion with an outer surface having a substantially smooth shape. The wall portion is configured to bend from raised position to a collapsed position, with the food container being used to retain food in the raised position and being collapsed for storage in the collapsed position.
US11021294B2	Dispensing containers A seal that forms part of a container for storing and dispensing consumer products is provided. The container can be used for the packaging of pills, tablets or capsules, or as a multi-cavity container for organizing and storing mixed medication for subsequent dispensation according to a predefined dosage regimen. The seal includes a cover film and a barrier film. The cover film has pre-formed lines of separation defining a removable portion per cavity. The barrier film is secured to the cover film by a layer of peelable adhesive and has pre-formed lines of separation defining the periphery of a barrier patch per removable portion. The cover film includes a tamper-indicating line of separation close to an edge of the cover film that is designed to tear if an attempt is made to peel the cover film away from the tray to expose one or more of the cavities.
US11021291B1	Refracting bottle A bottle is provided. In one aspect, the bottle includes an outer wall. An inner wall is surrounded by the outer wall and is separated from the outer wall by a first distance. A curved base extends from the inner wall. The curved base includes a concave area centrally disposed with respect to the inner wall. The concave area is configured to receive a tablet.
US11021290B2	Labeling machine A labeling machine having a device for applying labels to containers to be labeled, the application device being fed by a feeding unit supported by a base frame and including at least one device for supporting a spool of a film of labels which is arranged around a hollow tubular body. The supporting device includes at least one base body supported by the base frame and an elongated body which can be associated removably with the base body by virtue of a removable connecting component, the elongated body being insertable into the hollow tubular body of the spool when separated from the base body. Locking components are further provided which are adapted to lock the elongated body in the tubular body with the elongated body separated from the base body.
US11021286B1	Receptacle feeding system An article feeder assembly having a pocketed separator and a discharge tube configured to deliver articles to the pocketed separator. Some embodiments include an initial feeder assembly in overlying relation with a track extending from the initial feeder assembly to the discharge tube. Articles are oriented in end-to-end orientation in the initial feeder assembly and delivered to the pocketed separator in vertical end-to-end orientation. As pocketed separator rotates with respect to discharge tube, vertical retention members pass through a tunnel in the discharge tube and rotate articles out of the discharge tube. The discharged articles are secured in pockets delineated by the retention members. Some embodiments use one or more cam mechanisms to properly orient the discharged articles as the pocketed separator rotates. Properly oriented articles are then delivered to an advancing mechanism, such as a conveyor system.
US11021283B2	Method for transferring pre-incubated eggs to a poultry house and transfer machine used therewith A method is provided, wherein the eggs which are pre-incubated in setter trays are transferred to the poultry house in these setter trays. In the poultry house, a layer of insulating covering material is provided on the floor of the poultry house, in one or more strips. The covering material comprises, in particular, litter which is applied in a layer thickness of at least 2 cm. By a set of egg pickup members of a transfer machine, the pre-incubated eggs are removed in the poultry house from the setter trays, after which they are positioned on the covering material by the transfer machine. In this way, the eggs can be placed in the poultry house efficiently, with a minimal risk of damage to the eggs a high hatching rate being ensured.
US11021276B2	Method for producing a packaging material, and a method for producing a package A method for producing a packaging material comprises providing a core material layer of fibre-based material having an inner side and an outer side, embossing the core material layer for forming embossed features having an initial height, the embossed features protruding from the outer side of the core material layer to later form a tactile pattern on a side of the package to be formed by the packaging material, and laminating at least one layer to the inner side of the embossed core material layer such that the height of the embossed features is temporarily reduced to a minimum height.
US11021274B1	Cubesat system Small cubesat systems may be available for a lower cost, have a higher reliability, and be much simpler to use than conventional cubesats. A complete turnkey system solution may be provided, including the ground station and remote field units. The satellite, ground station, and field unit may be provided separately as kits that are ready to go out-of-the-box as soon as they arrive. This enables universities, researchers, and hobbyists to obtain and deploy their own functional satellites. Furthermore, theoretical designs and functionality may be rapidly prototyped and demonstrated, which allows for proof-of-concept without needing to build a larger, more expensive satellite system and hope that the new design or functionality works as intended.
US11021272B2	Control moment gyroscope A control moment gyroscope includes: an inner gimbal; a rotor that is held by the inner gimbal to be rotatable around a spin axis; a spin motor that is disposed on the inner gimbal, and that rotates the rotor around the spin axis; a stator that holds the inner gimbal to be rotatable around a gimbal axis that is perpendicular to the spin axis; gimbal bearings that are disposed between the inner gimbal and the stator to face each other from opposite sides of a plane that is perpendicular to the gimbal axis and that includes the spin axis, to be in contact with the plane in question, or to include the plane in question; and a torque module that is disposed on the stator, and that rotates the inner gimbal around the gimbal axis.
US11021270B2	Thermal management system for structures in space An antenna assembly has a solar layer having one or more solar cells generating solar power, an antenna layer connected to the solar layer and having electronic components utilizing the solar power generated by the solar layer, and a thermal dissipation device dissipating heat locally at the antenna assembly. A large number of antenna assemblies are connected to form an antenna array in which heat is generated locally at each antenna assembly and dissipated locally at each antenna assembly.
US11021262B2	Unlocking apparatus for a ram air turbine actuator An apparatus for unlocking an actuator comprises a first member mounted in a housing for longitudinal movement along an axis. A recess is formed in a surface of the first member. The apparatus further comprises a second member for operative connection to a lock release element of an actuator for movement in a direction generally transverse to the axis of movement of the first member. The second member has a follower element resiliently biased into contact with the surface of the first member. The apparatus further comprises an unlocking actuator for moving the first member along the axis between a first, locking position in which the follower element engages the surface and a second, unlocking position in which the follower element is at least partially received within the recess.
US11021261B2	Protective coatings for turbine blades and methods A protective coating composition for providing protection to a component of a ram air turbine system in need thereof. The protective coating composition comprises an aqueous-soluble or alkaline-soluble polymer matrix, one or more compressible fillers, and one or more non-compressible fillers. The disclosure also provides a method for providing a protective coating onto components of a ram air turbine system in need thereof for providing indentation and scratch resistance thereto.
US11021252B2	Compactor trolley for aeronautical applications A compactor trolley for aeronautical applications, more particularly a trolley provided with a drawer having a door with a safety closing system that incorporates a flap for direct access to the waste storage compartment, without the need to pull out the drawer and/or open the door.
US11021250B2	Airborne fire extinguishing system with infrared imaging and method An airborne fire extinguishing system includes a fluid reservoir, a flow control valve in fluid communication with the fluid reservoir, a deflector in fluid communication with the flow control valve, and an infrared camera. The fluid reservoir is configured to contain a fire extinguishing agent for suppressing a fire, particularly water. The flow control valve regulates a flow of the fire extinguishing agent between the fluid reservoir and the deflector. The deflector dispenses the fire extinguishing agent in a controlled manner such that the fire extinguishing agent is diffused in a specified concentration into the air. The infrared camera is configured to produce a thermographic image resulting from thermal radiation produced by a fire to help provide targeting means.
US11021249B2	Drone-based, attacker neutralization Methods and systems are provided for responding to an attacker including a shooter who opens fire at a site where people are gathered, including identifying, neutralizing, and restraining the attacker. A system may include a central control unit configured to receive signals indicative of gun fire, to responsively determine an origin of the gun fire, to identify features of a shooter associated with the gun fire and to release a UAV from a shielded UAV housing to engage the shooter. The UAV may be configured to fly towards the shooter, according to the origin of the gun fire and the identifying features of the shooter, and to neutralize the shooter by operating a UAV incapacitating mechanism.
US11021247B1	Source location determination by an aerial vehicle Described is system and method for determining a location of a client device. In one implementation, an unmanned aerial vehicle (UAV) receives an image of the UAV, obtained by the client device. The image is processed to determine a source area of the client device. As the UAV navigates toward the area, it scans the area for the client device and/or obtains additional information from the client device to aid in determining the location of the client device.
US11021245B2	VTOL aircraft A vertical take-off and landing aircraft is shown. The VTOL aircraft has a main wing having a left wing and a right wing configured as folding wings, and one or more of a foreplane, having a left canard and a right canard configured as folding wings, and/or a tailplane, having a left stabiliser and a right stabiliser configured as folding wings. Each one of the folding wings has a fixed inboard section and a folding outboard section. The folding outboard section is downwardly foldable to a landing condition to support the aircraft on a surface.
US11021242B2	Apparatus for providing rail-based vertical short takeoff and landing and operational control Apparatus for vertical or short takeoff and landing, and operational control during flight. In one embodiment, the apparatus includes a main body assembly, the main body assembly including: a fuselage, the fuselage includes one or more power motor assemblies and one or more actuator motor assemblies; a plurality of power mounting bodies and a plurality of power/articulation mounting bodies; a static rail that is operatively coupled with the plurality of power mounting bodies; a transient rail that is operatively coupled with the plurality of power/articulation bodies; and a plurality of airfoils, each of the plurality of airfoils being coupled to a respective power/articulation mounting body. Various sub-systems of the apparatus and methods of manufacture and use are also disclosed.
US11021240B2	Unmanned aerial vehicle An unmanned aerial vehicle (UAV) is provided. The UAV includes a first guard grill, a second guard grill configured to be removably combined with the first guard grill and form an external structure and an inner space of the UAV with the first guard grill, a housing configured to include a central portion located in the center of the inner space and embed a processor and a navigation system, one or more propelling elements configured to be located the inner space and be disposed around the central portion, and a plurality of motor assemblies configured to be located in the inner space and drive the propelling elements while being electrically connected with the processor. When viewed from the outside of the external structure, the propelling elements are partially covered by at least one of the first guard grill or the second guard grill.
US11021239B2	Shock strut shrinking system A system for shrinking landing gear includes a shock strut having a cylinder and a piston to be received by the cylinder. The system further includes an upper cam fastened to the piston and a lower cam fastened to the cylinder. The system further includes a brace configured to be coupled to the shock strut to lock the landing gear in a deployed position, and to fold towards the shock strut during retraction of the landing gear. The system further includes a collar coupled to the brace and the piston and configured to rotate relative to the cylinder in response to folding of the brace such that rotation of the collar rotates the piston and the upper cam relative to the lower cam, the rotation of the upper cam relative to the lower cam forcing the piston towards the aircraft attachment within the cylinder.
US11021237B2	Aircraft hydraulic system A sub-system 200 for an aircraft hydraulic system 20 that includes a first inlet 202 for receiving fluid from a supply 22 of hydraulic fluid, a system valve 210 for controlling fluid flow from the sub-system 200 to a hydraulically-operable system 24 of the aircraft hydraulic system 20, a check valve 220 for permitting fluid flow from the sub-system 200 and preventing or hindering fluid flow into the sub-system 200, a second inlet 240 for receiving fluid from a second supply 28 of hydraulic fluid, and a selector 230. The selector 230 configured to place the system valve 210 in fluid communication with the first inlet 202 when the selector 230 is in a first state, and to place the system valve 210 in fluid communication with the check valve 220 and the second inlet 240 when the selector 230 is in a second state different from the first state.
US11021225B2	Aircraft framework assembly, aircraft structural framework and aircraft with an aircraft structural framework A pole-shaped aircraft framework assembly including a first plug-and-turn connector forming a first end, a second plug-and-turn connector forming a second end, the second end opposite the first end, a first rod extending from the first plug-and-turn connector towards the second plug-and-turn connector, and a coupling component coupled to the second plug-and-turn connector for detachable coupling with the first rod. The first rod has a circumferential outer surface including alternately on a circumferential path in a cross-sectional plane of the first rod a ridged section and a plain section. The coupling component includes a tubular part having a circumferential inner surface including alternately on a circumferential path in a cross-sectional plane of the tubular part at least one ridged section and at least one plain section. One of the first rod and the coupling component is rotatable relative to the other one, engaging respective ridges of the first rod and the coupling component.
US11021215B1	Fully telescoping device mount A telescoping device mount is configured to hold an electronic device. The telescoping device mount is configured to fully extend or fully retract the electronic device. The telescoping device mount includes a telescoping post, a mount segment, and a base. The telescoping post includes an inner post segment and an outer post segment. The mount segment is configured to secure an electronic device thereto. The mount segment includes an outer collar slidably securable to the outer post segment of the telescoping post. The base is secured to the inner post segment such that the outer post segment telescopes relative to the inner post segment. In a fully retracted position, the electronic device is proximate to the base and/or an underlying surface.
US11021212B2	Bicycle battery unit with protector A bicycle battery unit is configured to reduce the effect of contact with an obstacle. The bicycle battery unit includes a plurality batteries, a housing accommodating the batteries and a protector. The protector is integrally provided on at least a portion of the outer surface of the housing. The protector has a lower hardness than a hardness of the housing.
US11021211B2	Electric assist bicycle Embodiments disclosed herein include an electric assist bicycle adapted for a both personal and public use, and subcomponents of the bicycle. The electric assist bicycle can include a hollow frame with one or more cables routed within the hollow frame. The hollow frame can be configured with an internal battery compartment. The electric assist bicycle can further include a modular electronic locking system.
US11021209B2	Pedal with detachable shoe platform and adjustable toe clip A pedal that includes a pedal body having a clipless structure and a member. The clipless structure includes a lip at a first portion of the pedal and a cleat at a second portion of the pedal. The pedal includes a detachable shoe platform having a cleat portion securable to the lip and a clip securable to the member. The detachable shoe platform may include an adjustable toe clip having a strap, which wraps around a shoe of a rider. The strap is adjustable by an adjustable strap fastener assembly having a lever coupled to a plate secured in a housing. The lever includes a first end biased against the strap and a second end engaged by a trigger. The trigger is operable to move the lever from a closed position to an open position against the bias force, thereby releasing the strap for adjustment.
US11021207B2	Bicycle brake A linear brake for a bicycle comprises a pair of pivot mounts, each of which is mounted on a bicycle member laterally of a wheel rim, one on either side of the wheel. A brake arm is pivotally mounted in levered relation on each pivot mount below adjacent and biased away from the wheel rim. A brake shoe is affixed to each brake arm upper end. A control cable is affixed to a control member above the wheel with the control member being connected to the center of a yoke cable. The yoke cable is affixed to the lower end of each brake arm with yoke cable passed partway around the annular component on each pivot mount.
US11021205B2	Electronic clutch assist apparatus A clutch assist apparatus that has a casing, a controller, a position sensor that communicates with the controller to identify the position of a hand lever, a motor controlled by the controller and coupled to the casing, a cable pulling lever pivotally coupled to the casing about a rotation axis and configured to be coupled to a clutch cable, the cable pulling lever being movable between a first position and a second position. Wherein, the cable pulling lever selectively transitions a clutch assembly between an engaged position when the cable pulling lever is in the first position and a disengaged position when the cable pulling lever is in the second position. Further wherein, the cable pulling lever is movable between the first position and the second position by either the motor or the hand lever.
US11021197B2	Compact magnetic crawler vehicle with anti-rocking supports A robotic vehicle for traversing surfaces is provided. The vehicle is comprised of a chassis supporting a magnetic drive wheel for driving and steering the vehicle and a stabilization mechanism. The magnetic wheel comprises two flux concentrator yokes and an axially magnetized hub extending therebetween. The hub includes a central housing configured to house a sensor probe and enhance the magnetic pull force of the wheel by providing a continuous pathway of high magnetic permeability material for magnetic flux to flow axially through the drive wheel. The stabilization mechanism comprises a front and rear facing support element moveably coupled to the chassis and configured to contact the surface and move symmetrically relative to the chassis thereby maintaining the vehicle and probe normal to the surface and providing stability to the vehicle while traversing surfaces regardless of surface curvature and vehicle orientation.
US11021195B2	Active front deflector An active front deflector assembly having a deflector panel, actuator, and linkage assemblies each with a predetermined geometry and ratio of links to each other for movement of the active front deflector assembly between at least a deployed position and a retracted position. The deflector panel is positionable at multiple heights. The assembly deploys and retracts based on vehicle requirements, and, when deployed, redirects the air flow in the front of the vehicle to improve the vehicle aerodynamics for either fuel economy or performance characteristics. Additionally, it allows for the deflector panel to retract so the vehicle meets ground clearances, etc. The deflector panel is also both rigid and semi-rigid to absorb impact energy. A drive shaft transmits the drive from one side to the other side. The deflector is both rigid and semi rigid to absorb impact energy.
US11021194B2	Air guiding arrangement for a motor vehicle An air guiding arrangement for a motor vehicle includes: a carrier arranged on a vehicle body, and on which an air guide is mounted such that the air guide is drivable from a retracted home position to an extended maximum position by a drive, a sensor arrangement that monitors the position of the air guide and is connected to a controller so as to transmit data corresponding to the position, the sensor arrangement comprising an electric field sensor arrangement to monitor the position of the air guide, at least one electromagnetic field source is provided in the air guide, and at least one electric field receiver, which is a sensor of the sensor arrangement, is provided in the carrier and/or in the vehicle body.
US11021187B2	Steering knuckle and method of making the same A steering knuckle is used in a motor vehicle and is typically positioned adjacent a front wheel thereof. The steering knuckle includes a central portion, a steering knuckle arm, an upper portion and a lower portion. The steering knuckle arm, the upper portion and the lower portion may each be contoured with full or partial roulette contoured surfaces (i.e., surfaces defined by roulette curves), and the upper portion may transition from a hollow lower portion to a solid upper portion defining an I-beam. A dual-beam horizontal support is formed in the central portion. The steering knuckle is formed from a casting process, and the roulette curvature of the steering knuckle arm, the upper portion and the lower portion provide draft to the surfaces of the steering knuckle which are perpendicular to the parting line of the casting mold, allowing the steering knuckle to be easily removed from the casting mold.
US11021171B2	Driving state within a driving environment that includes autonomous and semi-autonomous vehicles An example operation may include one or more of collecting a set of driving data, estimating, from the set of driving data, one or more states that are predictive of an elevated driving risk of an adverse event endangering at least one of a driver, a vehicle's occupants or a vehicle's cargo, determining, from the one or more estimated states, an existence of an elevated driving risk, and alerting at least one of the vehicle, driver or the vehicle's occupants to the existence of the elevated driving risk.
US11021169B1	Systems and methods for determining and using posted speed limits for vehicles Systems and methods to determine posted speed limits for vehicles and modify a centralized database of posted speed limits may manage the centralized database, receive, from a fleet of vehicles, requests to modify speed limits associated with roads, and modify the centralized database in accordance with the received requests for modification. Individual vehicles may compare a posted speed limit for a particular road as identified based on road-side image information with a previously stored speed limit from the centralized database for the same road in order to detect a discrepancy and transmit a request for a modification.
US11021163B2	Method for operating a motor vehicle system on the basis of a user-specific user setting, storage medium, assignment device, motor vehicle and sensor device for operating on the internet An approach is described for operating a motor vehicle system based on a user-specific user setting. A provided gene profile file is transferred to a deep learning engine that provides gene patterns of at least one predetermined gene range of persons and a respective preferred user setting for a large number of people. The deep learning engine processes the gene pattern of the person described by the gene profile file to thereby determine a configuration forecast of the user, the configuration forecast including a probability with which the user prefers one of the user settings. A user profile file is selected and transmitted to at least one motor vehicle system for configuring the at least one motor vehicle system based on the forecasted probability.
US11021155B2	Vehicle control apparatus and vehicle control method A vehicle control apparatus performs during-following control in which, when a direction indicator of an own vehicle is operated during traveling in which a preceding vehicle is followed, the own vehicle is accelerated in conjunction with the operation of the direction indicator. An adjacent vehicle selecting unit selects, from other vehicles present ahead of the own vehicle, an adjacent vehicle traveling in an adjacent lane adjacent to a traveling lane of the own vehicle based on a lateral position that is a relative position relative to the own vehicle in a direction orthogonal to a travelling direction of the own vehicle and a relative distance to the own vehicle in the travelling direction. An acceleration control unit performs acceleration of the own vehicle by the during-following control based on whether or not the adjacent vehicle is selected when the direction indicator is operated during following-traveling.
US11021154B2	Hybrid vehicle and method of braking hybrid vehicle In a hybrid vehicle, each of an engine and an MG1 is mechanically coupled to a drive wheel with a planetary gear being interposed. The planetary gear and an MG2 are configured such that motive power output from the planetary gear and motive power output from the MG2 are transmitted to the drive wheel as being combined. When a first condition is satisfied during traveling of the vehicle, a controller stops combustion in the engine and performs motoring by the MG1 such that the planetary gear outputs deceleration torque. When a second condition in addition to the first condition is satisfied (YES in S20) during deceleration of the hybrid vehicle with deceleration torque, the controller performs motoring with throttle opening being set to first opening or larger and WGV opening being set to second opening or smaller.
US11021153B2	Control apparatus of electric vehicle A control apparatus of an electric vehicle including a motor capable of outputting a vehicle driving force that is a driving force acting on the electric vehicle, and a brake device configured to generate a vehicle braking force that is a braking force acting on the electric vehicle in accordance with a brake operation performed by a driver, includes: a controller. The controller is configured to start a first hill-hold control for maintaining the electric vehicle in a stopped state by using the vehicle driving force generated by the motor as a stopping force for stopping the electric vehicle when the brake operation is interrupted.
US11021150B2	Controlling a motor vehicle based upon wind One or more devices, systems, and/or methods for controlling a motor vehicle based upon wind are provided. For example, a first measurement of wind detected by a first sensor coupled to the motor vehicle may be received from the first sensor. A second measurement of wind associated with a location of the motor vehicle may be received from a server. A wind effect (e.g., cost, inefficiency, danger, etc.) on the motor vehicle may be determined based upon the first measurement of wind and/or the second measurement of wind. A corrective action for the motor vehicle may be determined based upon the wind effect, and may be implemented on the motor vehicle.
US11021149B2	Driving support apparatus A driving support apparatus is provided to improve accuracy of the driving support such as a notification to the driver and the vehicle control. In the apparatus, a common parameter indicating a location of a lane boundary is calculated for the vehicle control, based on an actual boundary line where a location of the lane boundary line existing at both sides of the vehicle is actually measured. A common error is defined as an error between the location of an estimated boundary indicated by the common parameter and a location of the actual boundary line. In the case where the common error is larger than or equal to a common threshold in which an amount of the common error is set in advance, the apparatus determines that the travelling road where the vehicle travels is branched and stops the vehicle control using the common parameter.
US11021144B2	Slip detection and mitigation for an electric drive powertrain having a high ratio traction drive transmission A method of controlling a continuously variable electric drivetrain (CVED) including a high ratio traction drive transmission and at least one of a first motor-generator and a second motor-generator is disclosed. The method includes the steps of receiving a an output speed, determining a kinematic output speed, and determining a slip state of the high ratio traction drive transmission based on a comparison of the output speed to the kinematic output speed.
US11021141B2	Electric brake system An electronic brake system of the present disclosure is disclosed. The an electronic brake system may include a reservoir to store oil; a master cylinder having a master piston connected to a brake pedal and a master chamber for discharging oil by a displacement of the master piston; a hydraulic pressure supply apparatus generating hydraulic pressure by an electrical signal output corresponding to a displacement of the brake pedal to supply to wheel cylinders of the respective wheels; a hydraulic control unit transmitting the hydraulic pressure discharged from the hydraulic pressure supply apparatus to the wheel cylinders of the respective wheels; and a redundancy control apparatus generating hydraulic pressure using a motor and a pump to transmit to at least one of the wheel cylinders.
US11021140B2	Vehicle brake system having plunger power source The invention relates to an improved plunger assembly for a vehicle brake system. The plunger assembly is operable as a pressure source to control brake fluid pressure supplied to one or more wheel brakes. The plunger assembly comprises a housing defining a cylinder; a reversible motor supported by the housing and having a rotor; and a linear actuator such as a ball screw/nut mechanism driven by the motor. A plunger head is mounted in the cylinder and driven by the linear actuator in first and second opposite directions. Improvements include a linear actuator rotationally supported on the housing by a bearing to actuate the plunger head connection to a ball screw.
US11021130B2	Curtain airbag of vehicle A curtain airbag of a vehicle is provided adjacent to the roof of the vehicle in a folded state, is configured to have a shape that unfolds downward between an inner side surface of the vehicle and an occupant when the vehicle crashes, and includes an outer panel that proceeds toward the side surface of the vehicle and an inner panel that proceeds toward the occupant upon expansion. The curtain airbag further includes a head support part configured to have a shape in which an expansion thickness, which is defined by the outer panel and the inner panel in a portion that the head of the occupant contacts due to the car crash, gradually increases toward the front of the vehicle, so as to prevent the head of the occupant from rotating while moving toward the front of the vehicle. The curtain airbag may effectively stop the head of the occupant from rotating while moving toward the front of the vehicle during a vehicle crash.
US11021129B2	Occupant restraint device An occupant restraint device including: right and left airbags stored inside right and left sides of a seat back of a vehicle seat, respectively; right and left tension cloths connected to outer surfaces of the right and left airbags, respectively; and a lower tension cloth disposed inside a seat cushion of a vehicle seat, the lower tension cloth being continuously connected between lower parts of the right and left tension cloths. The lower tension cloth is movable in right and left directions with respect to an occupant sitting in the vehicle seat. When the right and left airbags are expanded and deployed, the right tension cloth, the left tension cloth, and the lower tension cloth are configured to push the expanded and deployed right and left airbags toward the occupant.
US11021128B2	Deployable roof containment system and method One general aspect includes a deployable containment system for a vehicle roof panel, the system including: a pair of guide channels proximate to an opening through the vehicle roof panel, each guide channel of the pair having a first end and a second end; a housing mounted to the first end of the pair of guide channels. The deployable containment system also includes a shield configured to deploy from the housing and travel along the pair of guide channels so as to cover at least a portion of the opening. The deployable containment system also includes an actuator disposed proximate to the pair of guide channels, the actuator configured to deploy the shield from the housing after a deployment event.
US11021127B2	Vehicle airbag that forces a head restraint to a forward position during inflation of the airbag A seating assembly for a vehicle comprises: a seatback; an airbag having a stowed position and an inflated position, the airbag being configured to inflate from the stowed position to the inflated position in response to the vehicle impacting an object; a head restraint coupled to the seatback, the head restraint including a forward position, a rearward position, and a locking mechanism preventing the head restraint from moving from the forward position to the rearward position after taking the forward position; and as the airbag inflates from the stowed position to the inflated position, the airbag forces the head restraint from the rearward position to the forward position. As the airbag inflates from the stowed position to the inflated position and forces the head restraint to the forward position, the airbag does not contact the one or more support bars and does not force the seatback to change position.
US11021125B2	Steering wheel assembly having pivotable airbag module A steering wheel assembly includes a steering wheel and an airbag module. The steering wheel includes a hub portion that has a hook member and a first bracket opposed to the hook member and having an access hole. The airbag module is pivotably attached to the hub portion of the steering wheel and includes a latch member and a second bracket opposed to the latch member and having an access hole. The latch member is pivotably attached to the hook member, and the first bracket and the second bracket overlap with each other such that the access holes form a port that receives a fastener.
US11021118B2	Wire harness manufacturing method and wire harness A method for manufacturing a wire harness includes: disposing a trunk harness, a branch harness and control boxes on a workbench and attaching the trunk harness and the branch harness to the control boxes; connecting the control boxes to an external device via the branch harness; and switching operation mode of at least one of the control boxes to an information writing mode for inputting information for operating the electric component to be connected to the branch harness into the at least one of the control boxes and then inputting the information from the external device into the at least one of the control boxes via the branch harness.
US11021114B2	Door trim assembly with bracket joining the armrest and the pull handle of that assembly A door trim assembly includes an armrest, a pull handle, including a receiver, and a bracket joining the armrest and the pull handle. The bracket includes a connection feature that engages with the receiver. The bracket is cantilevered to the pull handle and includes a second end with an abutment surface engaging the armrest.
US11021106B2	Vehicle, side mirror assembly for a vehicle, and methods thereof According to various aspects, a vehicle may include: an external structure; an assembly configured to allow a movement of at least a part of the assembly relative to the external structure at least from a first position to a second position, wherein the assembly protrudes from the external structure with a first distance in the first position and with a second distance less than the first distance in the second position; one or more sensors configured to receive obstacle information associated with one or more obstacles in a vicinity of the vehicle; one or more processors configured to determine a collision threat to the assembly based on the obstacle information, and trigger the movement of at least the part of the assembly from the first position into the second position in the case that the collision threat is determined.
US11021105B2	Bird's-eye view video generation device, bird's-eye view video generation method, and non-transitory storage medium A bird's-eye view video generation device includes a video data acquisition unit that acquires surrounding video data of a vehicle captured by imagers, a surrounding information acquisition unit that acquires surrounding information around the vehicle, a vehicle information acquisition unit that acquires vehicle information, a bird's-eye view video generation unit that generates a bird's-eye view video of the vehicle based on the acquired surrounding video data, and a display controller that causes a display to display the bird's-eye view video in at least one of a case in which a surrounding vehicle turns on a direction indicator, and a case in which an entrance/exit into/from which the vehicle can enter/exit or a starting point of a branch lane is located at the side of the vehicle based on the vehicle and/or surrounding information.
US11021103B2	Method for enriching a field of view of a driver of a transportation vehicle with additional information, device for use in an observer transportation vehicle, device for use in an object, and transportation vehicle A method for enhancing a field of view of a driver of a transportation vehicle with supplementary information, in which the supplementary information is depicted via a display unit display. Observation of the surroundings of the transportation vehicle takes place and, in response to the observation of the surroundings having detected a relevant object for which a potential significance arises, the relevant object is depicted on the display unit and the relation to the real object is emphasized in the field of view of the driver by the depicted object being visually highlighted in an environmentally synchronous state with respect to the real object. Also disclosed is an appropriately designed apparatus for use in an observer transportation vehicle, an appropriately designed apparatus for use in an object, and a transportation vehicle.
US11021101B2	Method and system for augmented alerting based on driver's state in hybrid driving The present teaching relates to method, system, and medium, for generating an augmented alert in a hybrid vehicle. First information indicating an upcoming switch in an operating mode of the vehicle is received, which specifies a set of tasks, arranged in an order, to be completed by a driver in the vehicle to achieve the upcoming switch, and a task duration for each of the set of tasks by which the task is to be completed. A current state of the driver is obtained and used to determine a set of warnings to alert the driver to perform the set of tasks. Each warning corresponds to a task in the set of tasks and is created based on the current state of the driver. A warning schedule is generated based on the set of warnings in the order of the set of tasks and transmitted so that warnings in the warning schedule are delivered to the driver.
US11021098B1	Illuminating vehicle closure member systems for providing exterior lighting effects This disclosure details illuminating vehicle closure member systems for selectively producing various exterior lighting effects. Exemplary closure member systems may include a closure member and a discrete illuminating section secured relative to the closure member and including a lighting module that is configured to produce at least one of a beltline lighting effect, a motion path lighting effect, or an operation status lighting effect at or near the closure member. A control module may control the various lighting effects emitted by the illuminating closure member system.
US11021095B2	Replacement multifunction automobile light system and method A remotely controllable headlight assembly for use on a vehicle, the assembly comprising a circuit board including a plurality of LEDs including at least a first low beam LED, a first high beam LED and at least one additional LED, optic elements supported adjacent the LEDs on the circuit board, a processor and a remote communication module coupled to the processor, the remote communication module configured to receive commands from a wireless device, wherein the commands instruct the processor to illuminate the at least one additional LED, wherein the processor controls the at least one additional LED based on the received wireless commands.
US11021094B2	Magnetic strap hook The present invention provides a magnetic strap hook belonging to the technical field of logistics appliances. The present invention solves the problem that unhooking is easy to occur during usage of the magnetic strap hook in the prior art because the magnet is fixed on the hook body. The magnetic strap hook comprises a hook body, a magnet holder fixed on the hook body, and a magnet connected on the magnet holder. The hook body comprises a connector portion, and a hook portion connected to the connector portion and located at a front side of the connector portion. The magnet on the magnet holder is capable of moving back and forth relative to the hook body and/or swinging along front and rear directions of the hook body. The magnetic strap hook has the advantage of better stability of attraction of the strap hook during the process of binding goods.
US11021092B2	Positionable platform with a releasable locking mechanism A positionable platform for an interior of a vehicle comprising: a planar top surface; a bottom housing with a channel; and a releasable locking mechanism disposed between the planar top surface and the bottom housing. The releasable locking mechanism includes: a first bracket; a second bracket layered beside the first bracket; a button accessible for manipulation connected to the first bracket; a locked state where the second bracket extends into the channel; and an unlocked state where the movement of the button in a first direction causes movement of the first bracket in the first direction, which causes movement of the second bracket in a second direction different than the first direction that withdraws the second bracket from the channel or reduces the extension of the second bracket into the channel.
US11021091B2	Side member for a vehicle seat, vehicle seat A side member (10) for a vehicle seat (1), in particular motor vehicle seat, includes a metallic frame section (12). The frame section (12) has an exposed supporting section (14) for supporting a padding of the side member (10), wherein the supporting section (14) is flexurally elastic and, in a normal position, protrudes from the frame section (12) in order to support the padding, wherein at least one electrically controllable actuator (20) is provided, which, by generating a force, transfers the supporting section (14) from the normal position into a retracted position. The invention furthermore relates to a vehicle seat (1) having at least one side member (10).
US11021082B2	Second row priority seating for vehicles Aspects of the disclosure relate to vehicles capable of autonomous driving. These vehicles may include seats for accommodating different numbers of passengers. In some cases, the seats may be reconfigurable. For instance, a vehicle may include a first row of seating having a first, passenger use configuration. The first row may allow a passenger to sit in a seat of the first row of seating and access user input controls for the vehicle. The first row of seating may also have a second, folded configuration where the first row is in a folded configuration and no longer usable for passenger seating. The vehicle may also have a second row of seating. When the first row of seating is in the second, folded configuration, the second row of seating may still be usable for seating and may include additional legroom for the passenger as compared to when the first row of seating is in the first passenger use configuration.
US11021077B2	Vehicle power supply system A vehicle power supply system includes a first drive motor, a second drive motor, a first power line to which a first inverter and a first battery are connected, a second power line to which a second inverter and a second battery are connected, a voltage converter that convert a voltage between the power lines, and a charging and discharging control device that controls charging and discharging of the batteries and by operating the inverters and and the voltage converter. A vehicle is able to travel in a drive mode of any of an all-wheel drive mode and a two-wheel drive mode. The charging and discharging control device drives the first drive motor with power that is discharged from the first battery in a case where the drive mode is the two-wheel drive mode.
US11021071B2	Electric work vehicle Disclosed is an electric work vehicle that includes a traveling vehicle body, a wheel unit having wheels on the right and left sides of the traveling vehicle body, a motor for supplying rotational drive force to the wheel unit, and a battery for supplying electric power to the motor. The battery includes a first battery disposed at a right/left center of the traveling vehicle body, and second batteries disposed in right/left symmetricity on the traveling vehicle body to act as supplementary batteries.
US11021068B2	Vehicle control device and control method A method for controlling a vehicle that includes a motor configured to provide a driving/braking force to the vehicle and a friction braking mechanism configured to provide a friction brake force to the vehicle includes a target calculation step of calculating a target torque of the motor in accordance with a displacement of an accelerator pedal, a gradient estimation step of estimating a gradient torque to cancel a disturbance due to a gradient of a road surface where the vehicle is travelling, a command calculation step of calculating a torque command value of the motor based on the gradient torque and the target torque, a control step of controlling a torque of the motor in accordance with the torque command value, and a stop control step.
US11021067B2	Electrically powered vehicle and control method for electrically powered vehicle An electrically powered vehicle includes electric power lines through which electric power supplied from external charger flows, an electric power storage device electrically connected to the electric power lines, a charging circuit electrically connected to the electric power lines, and an electronic control unit. The electric power storage device is configured to be charged with the electric power from the external charger. The charging circuit is configured to charge the electric power storage device in either a first state or a second state. The electronic control unit is configured to acquire charger information indicating information related to electric power to be suppliable from the external charger, generate the command by using the acquired charger information, and output the command to the charging circuit.
US11021064B2	Battery pack heating apparatus and method of battery pack heating control The present disclosure provides a battery pack heating apparatus. The battery pack heating apparatus is applicable portably and externally to a vehicle and includes: an electrical energy conversion component, including an energy storage device, a first set of switches and a second set of switches; a heating interface component including a plurality of heating interfaces connected to the energy storage device via the first set of switches to form a first heating loop and connected to the energy storage device via the second set of switches to form a second heating loop, each of the plurality of heating interfaces being configured to be connected to a battery pack of one vehicle; and a heating control module configured to control a direction of electrical energy transfer between the electrical energy conversion component and the battery pack.
US11021060B2	Method for the automated guiding of a motor vehicle occupied by a driver and for the information of the driver A method for guiding a motor vehicle occupied by a driver during a vehicle journey in an automated manner by a driver assistance system includes: displaying, on an optical display apparatus of the driver assistance system, to the driver information from the driver assistance system relevant to the journey; and displaying the information relevant to the journey on the optical display apparatus by a plurality of different display pages assigned to different information classes. The display pages are displayed sequentially and in a stipulated order.
US11021059B2	Vehicular display assembly having a foldable flexible display device with storage box This disclosure relates to a vehicular display assembly and a vehicle, and the vehicular display assembly includes: a storage box; and a display device arranged on an opening side of the storage box, wherein the display device includes a laid state or a folding state, wherein the display device which is laid shields the opening of the storage box, and the display device which is folded exposes at least a part of the opening of the storage box.
US11021057B2	Transfer case with range and mode actuator having cam follower mechanism to overcome blocked shift events and sensor configuration permitting detection of fork positions A transfer case with an actuator for operating a two-speed transmission (i.e., range mechanism) and a clutch (i.e., mode mechanism). The actuator employs a motor-driven cam structure that coordinates the movement of a first fork, which is associated with the range mechanism, and a second fork that is associated with the mode mechanism. A resilient coupling is employed to provide compliance between the motor and the cam structure in the event that tooth-on-tooth contact inhibits the range mechanism from changing from a high-range mode and a low range mode. Compliance is provided between the cam structure and the second fork in the event that tooth-on-tooth contact inhibits the mode mechanism from changing from a 2WD mode to a 4WD mode. A sensor system identifies the placement of the first and second forks in various positions and responsively generates associated sensor signals.
US11021056B2	Work vehicle A work vehicle including a floor, a forward pedal arm, a reverse pedal arm, a forward rotation shaft, and a reverse rotation shaft. The floor has a first insertion hole and a second insertion hole. The forward pedal arm is placed in the first insertion hole and provided with a forward pedal. The reverse pedal arm is placed in the second insertion hole and provided with a reverse pedal. The forward rotation shaft serves as a rotation shaft of the forward pedal arm, and is oriented so that an outer end thereof is directed toward the rear of a vehicle body of the work vehicle. The reverse rotation shaft serves as a rotation shaft of the reverse pedal arm, and is oriented so that an outer end thereof is directed toward the rear of the vehicle body.
US11021055B2	Motor vehicle including an electric axle A motor module for modularly making a front and/or rear electric axle, comprising an electric motor generator and a gear train enclosed in a gearbox case permanently fixed to a stator of said electric motor-generator, the module having an L-shape. Electric axle comprising a pair of L-shaped modules for making a T-shaped front electric axle and a U-shaped rear electric axle.
US11021052B2	Capless closure assembly for fuel-tank filler pipe A capless filler pipe closure is provided for a tank filler pipe. The capless closure permits a fuel pump nozzle to be inserted into the tank filler pipe without first removing a fuel cap form the outer end of the tank filler pipe.
US11021051B2	Liquid vehicle tank comprising a fastened component A liquid vehicle tank (1) having a wall made of a plastic material, the tank (1) comprising a component (3, 5) affixed to the wall, the component (3, 5) having a portion (10) embedded in the wall, the embedded portion (10) having an external surface (21) a part of which is chemically incompatible with the plastic material of the wall, wherein the tank (1) also comprises a strengthening element welded to the wall over the embedded portion (10) of the component (3, 5).
US11021048B2	Window weather strip arrangement A window weather strip arrangement for covering at least sections of a window well of a motor vehicle includes a window weather strip carrier which can be secured on a vehicle skin and has a reinforcing core and a carrier sleeve accommodating the reinforcing core. The window weather strip arrangement further includes a window weather strip secured to the window weather strip carrier. The window weather strip carrier has a vehicle skin receiving portion for receiving sections of the vehicle skin and the window weather strip is secured to the window weather strip carrier on a side of the window weather strip carrier facing away from the vehicle skin receiving portion. A lamp is arranged in a lamp-receiving opening of the window weather strip and the reinforcing core protrudes out of the carrier sleeve overlapping with at least sections of the lamp-receiving opening, such that at least sections of the reinforcing core function as a reflector for the lamp.
US11021047B2	Bed cover of pickup truck This invention is relevant to a bed cover of pickup truck. The bed cover of pickup truck includes one bed cover. The bed cover includes at least two plates. The adjacent plates are connected by rotating shaft structure. The rotating shaft structure includes a plate-like pedestal, two connectors which form a rotary connection with the pedestal. This invention provides a bed cover of pickup truck with simple structure and great leading function. The drainage channel in the invention are big and will not cause syphonage. Thus the leading function will be better, requirement of the assembly accuracy will be lower and the production will be easier.
US11021046B2	Retractable overhead shade A retractable overhead assembly for a vehicle having a retractable cover (912) under tension and an integrated stiffening rod that includes attachment features (916) to selectively connect to a windshield area. The retractable system is self contained within an extrusion keeping the overall package size small and the installation/removal simple. The retractable cover creates a sun shade over the vehicle front cockpit and/or rear passenger area when deployed, and is retractable to a stowed position. The retractable overhead assembly is installable under any hard or soft top assembly configuration, and does not impede use or operation of the hard top or soft top assembly.
US11021044B2	Vehicle air conditioner device There is disclosed a vehicle air conditioner device of a so-called heat pump system to accurately perform efficient and comfortable heating of a vehicle interior. The vehicle air conditioner device includes a heating medium circulating circuit 23 which heats air to be supplied from an air flow passage 3 to a vehicle interior. A controller calculates a required heating capability TGQhtr of the heating medium circulating circuit to complement a shortage of an actual heating capability Qhp to a required heating capability TGQ of a radiator 4. The controller calculates a decrease amount ΔQhp of the actual heating capability Qhp from a difference ΔTXO between a refrigerant evaporation temperature TXO of an outdoor heat exchanger 7 and a refrigerant evaporation temperature TXObase in non-frosting, and adds the decrease amount ΔQhp to the required heating capability TGQhtr to execute the heating by the heating medium circulating circuit.
US11021037B2	Thermal management system The present invention relates to a thermal management system including: a refrigerant circulation line including a refrigerant circulator, a first heat exchanger, a first expander and a third heat exchanger, wherein refrigerant circulates in the refrigerant circulation line; a heating line for heating the interior by circulating cooling water exchanging heat with the refrigerant through the first heat exchanger; and a cooling line for cooling heating sources by exchanging heat between the cooling water and air or exchanging heat between the cooling water and the refrigerant.
US11021036B2	Battery electric vehicle and method to cool a high voltage powertrain component of a battery electric vehicle A battery electric vehicle includes a passenger cabin, a refrigerant circuit adapted to cool the passenger cabin, a powertrain including a high voltage powertrain component, a coolant circuit adapted to cool the high voltage powertrain component and a control module. The refrigerant circuit includes a condenser and an evaporator. The coolant circuit includes a radiator downstream from the condenser. The control module is configured to recirculate cabin air to the passenger cabin in response to data indicating temperature of the high voltage powertrain component exceeds a predetermined threshold temperature in order to reduce the air outlet temperature at the condenser and the air inlet temperature at the radiator. A related method to cool a high voltage powertrain component of a battery electric vehicle is also disclosed.
US11021030B2	Air suspension arrangement An air suspension arrangement arranged to be connected between a vehicle axle and a vehicle chassis of a vehicle includes a flexible bellows having an upper portion connectable to the vehicle chassis of the vehicle, and a bumper stop, wherein the air suspension arrangement further includes a polymer member arranged between the bumper stop and the flexible bellows for connecting the bumper stop to the flexible bellows. A method for manufacturing the air suspension arrangement and a vehicle including such an air suspension arrangement are also provided.
US11021025B2	Tire assembling device A tire assembling device includes a main body, a holding portion, an abutting surface, a guiding portion, a pressing portion and a protrusion. The main body has a top surface. The holding portion is connected to one side of the main body. The abutting surface connected to another side of the main body is for abutting against a rim surface of the rim. The guiding portion located between the abutting surface and the top surface is extended inclinedly corresponding to a radial direction of the rim. The pressing portion extended from the guiding portion toward a reference direction is protruded from the abutting surface and connected to the top surface. The protrusion protruded from the pressing portion forms a hook portion with an upper edge of the pressing portion and the abutting surface. The hook portion is for hooking a first edge of the rim.
US11021020B2	Method for arranging stud pins in pneumatic tire A method for arranging stud pins in a pneumatic tire is a method for arranging stud pins in a tread portion at intervals in a tire width direction so as to form a plurality of rows. This method includes specifying an inner region, an intermediate region, and an outer region by virtually partitioning the tread portion into equal three parts from a center line extending in a tire circumferential direction to a ground contact end in the tire width direction outward. The method also includes arranging the stud pins such that among numbers of stud pins per row in the inner region, the intermediate region, and the outer region, the number in the outer region is the largest, the number in the intermediate region is the second largest, the number in intermediate region is the smallest.
US11021019B2	Pneumatic tire A pneumatic tire comprises a first main groove disposed in a tread surface on either side of a tire equatorial plane, the first main grooves extending in a tire circumferential direction; a second main groove disposed outward of each of the first main grooves in a tire width direction, the second main groove extending in the tire circumferential direction; five land portions defined by the four main grooves, the five land portions including a center land portion located between the first main grooves, two intermediate land portions located between the first main grooves and the second main grooves, and two shoulder land portions located outward of the second main grooves in the tire width direction; and sub grooves and sipes disposed in each of the land portions.
US11021013B2	Wheelchair backrest and rear wheel assembly A system of bracket assemblies for a wheelchair comprises a pair of bracket assemblies adapted to be connected to respective sides of a seat frame of the wheelchair. Each of the bracket assemblies has a base adapted to be secured to a seat frame member of the seat frame, an arm adapted to be secured to a backrest frame member of a backrest frame, and a pivot pivotally connecting the base to the arm for rotational movement of the arm relative to the base. One or more blocking mechanism blocks the rotational movement of the arm relative to the base in a use orientation of the backrest frame. A rod having opposed ends connected to the base of the pair of the bracket assemblies for spacing the bracket assemblies away from one another. A rear wheel unit is also provided.
US11021010B2	Shielding assembly for side of tire A shielding structure for a wheel having a turning axis, a rim, and a tire mounted to the rim for rolling against an underlying surface. The wheel has axially oppositely facing sides. A mounting assembly is attached to the rim to move as one piece therewith. A plurality of shielding components are attached to the mounting assembly to overlie at least a part of the tire at one of the axially oppositely facing sides of the wheel. At least one of the shielding components is made from a non-metal material and a reinforcing element.
US11021008B2	Drive mechanism for transposition and stirring by single disc single motor A drive mechanism for transposition and stirring by single disc single motor includes a rotating transposition disc, wherein the transposition disc is a single-layer transposition disc, at least one gear set in which a gear ring is engaged with a planetary gear is arranged successively from inside to outside with the rotating shaft of the single-layer transposition disc as the center, the gear ring of each gear set is fixed on a rack, and the planetary gear engaged with the gear ring is rotationally installed on the transposition disc to serve as a driving gear of a stirring shaft of a color matching paint bucket. By adoption of the above technical solution, the present invention has the following beneficial effects: the structure is reasonable, the parts and components of the color mixing machine are reduced without reducing and decreasing the functions of the color mixing machine.
US11021007B1	Laminated film for molded decoration The present invention provides a laminated film for molded decoration including a transparent polymer substrate, a hard coat layer having a thickness of 2 to 10 μm, and a protective layer having a thickness of 50 to 200 nm laminated in that order, in which the hard coat layer is a cured layer of a hard coating composition, the protective layer is a cured layer of a coating composition for forming a protective layer, the laminated film for molded decoration has an extension rate within a range of 15 to 80%, and after a scratch test involving 200 reciprocations under a load of 2 N per 4 cm2 of a surface of the laminated film for molded decoration, the laminated film for molded decoration has no scratches and no deterioration in visibility due to change in appearance.
US11021006B2	Edge profile for a sheet-like material, and sheet-like material The present invention relates to an edge profile for a sheet-like material including a layered structure with a main body made of plastic which has a first base colour tone, with a decorative base material which has a second base colour tone, and with a decorative print. A final decoration which has a third base colour tone is formed at least from decorative base material and decorative print together. The decorative base material is a layer arranged between main body and decorative print. For easier production, the invention proposes that the decorative base layer is a layer of plastic co-extruded with the main body. The invention also relates to a sheet-like material with a corresponding edge profile.
US11021002B2	Near infrared absorbing fine particle dispersion liquid and method for producing the same, anti-counterfeit ink composition using near infrared absorbing fine particle dispersion liquid, and anti-counterfeit printed matter using near infrared absorbing fine particles Provided are a near infrared absorbing fine particle dispersion liquid having an absorption ability in a near infrared region, a clear contrast, and applicable to offset printing, and a method for producing the same, an anti-counterfeit ink composition using the near infrared absorbing fine particle dispersion liquid and an anti-counterfeit printed matter using near infrared absorbing fine particles. Also provided are a near infrared absorbing fine particle dispersion liquid containing a solvent of one or more kinds selected from petroleum-based solvents; near infrared absorbing fine particles in an amount of 2 mass % or more and 25 mass % or less, selected from one or more kinds of hexaboride fine particles expressed by a general formula XBa, and a dispersant soluble in the solvent and having a fatty acid in its structure, and an anti-counterfeit ink composition containing the near infrared absorbing fine particle dispersion liquid.
US11021000B2	System and method for positioning printed products in operative connection with a delivery system A system, preferably a saddle stitcher, includes: a transport chain, which is roof-shaped in an upper region, along which one or more printed products is astride transportable, collected, and are optionally stapled in an intermediate stapling station; and a stop adjustable according to a format of a printed product of the printed products, the stop being arranged in a transport direction of the printed product, behind the stapling station, and along a further course of the transport chain. The stop is in operative connection with a delivery system and an ejector that operate interdependently with each other to perform a format-stabilized discharge of the printed product in accordance with a cycle; and that the format-stabilized printed product is fed to a cutting apparatus.
US11020996B2	Abnormality warning method and abnormality warning system A method for warning an abnormality of a target object by using a self-organizing map prescribed by a plurality of nodes indicating a normal state of the target object includes acquiring detection data indicating a state of the target object, performing learning of the self-organizing map by using the detection data indicating a distance between a feature value and a node smaller than an abnormality threshold value predefined, storing the detection data indicating the distance larger than the abnormality threshold value in a storage unit as recorded data, and performing notification of the abnormality of the target object when the number of pieces of the recorded data stored in the storage unit reaches a predetermined number.
US11020987B2	Method for ink pressure modulation in a printer for axially symmetric objects An ink pressure modulation method is presented in a direct-to-shape printing system for applying images on the exterior of an axially symmetrical media object that has a contoured, varying exterior surface, such as occurs on curved wine bottles and sports equipment like bats. The method varies ink pressures based on the movement positions of each print head as they move over the surface of the media object. A movement-based formula is presented to allow for continuous updating of pressures in ink tank manifolds to allow independent changes in pressure to each inkjet print head during printing.
US11020985B2	Image processing apparatus, image processing method and storage medium The image processing apparatus includes: an acquisition unit configured to acquire a pixel value group consisting of pixel values of a plurality of pixels included in a predetermined target area in image data; an acquisition unit configured to acquire a threshold value group consisting of a plurality of threshold values corresponding to the plurality of pixels; a calculation unit configured to calculate a target number of dots indicating a number of dots to be arranged within the target area; an acquisition unit configured to acquire a pixel position at which a dot is expected to be formed by a non-ejectable nozzle in the image data as a non-ejectable nozzle position; and determination unit configured to determine arrangement of dots in the target area based on a priority level determined based on the pixel value group and the threshold value group, the target number of dots, and the non-ejectable nozzle position.
US11020984B2	Multilayer white printing with white-balance White-balance is improved when printing on colored media, while minimizing the time and use of costly materials required by present approaches. In an embodiment, the typical solid white fill or background layer is altered by including in the white layer one or more of the other colors already available in the printer to shade this layer. Thus, a small amount of cyan, for example, helps balance a pink-ish (red) media; yellow is used for blue media; and magenta is used for green media; as well as combinations thereof. A combination of transparent process inks and opaque white helps to maintain brightness (luminosity).
US11020983B2	Liquid ejecting device and liquid ejecting method Provided is a liquid ejecting device that includes an ejecting unit configured to eject liquid and a control unit that performs control to apply the liquid to a medium. The ejecting unit is configured to eject, as the liquid, ink, that contains a color material, and inhibitor for inhibiting penetration of the color material into the medium. The control unit is configured to select a first printing mode in which applying the ink to the medium without applying the inhibitor to the medium, and a second printing mode in which applying the inhibitor to the medium and applying the ink to the medium applied with the inhibitor. The control unit causes an amount of the ink applied per unit area in the second printing mode to be smaller than an amount of the ink applied per unit area in the first printing mode.
US11020981B2	Liquid ejection device A liquid ejection device includes a liquid supply unit configured to supply liquid to a liquid ejection head, a first supply passage, a second supply passage, a return pipe and a short-circuit pipe serving as a liquid flow passage, and a pump mechanism. A controller executes an ejection control for supplying the liquid from a pressure chamber to the liquid ejection head by opening first and second valve bodies and closing third and fourth valve bodies, a first circulation control for circulating the liquid through the liquid ejection head by closing the first and fourth valve bodies, opening the second and third valve bodies and operating the pump mechanism, and a second circulation control for circulating the liquid through the short-circuit pipe by closing the second valve body while opening the first, third and fourth valve bodies and operating the pump mechanism with an air vent mechanism released.
US11020978B2	Printing-fluid cartridge including electrical interface and locking surface A printing-fluid cartridge is inserted into a printing-fluid consuming apparatus in an insertion direction crossing a gravitational direction and attached thereto in a first posture. The printing-fluid cartridge includes a front surface, a rear surface, a storage chamber, a supply portion having a supply port, an upper surface, an electrical interface disposed at the upper surface, and a locking surface. The printing-fluid cartridge inserted in the printing-fluid consuming apparatus is pivotable between the first posture and a second posture. The electrical interface is positioned closer to the supply port than the locking surface is to the supply port in the insertion direction. The electrical interface is positioned rearward relative to the pivot center in the insertion direction. The locking surface is positioned upward relative to the storage chamber and closer to a rearmost point of the printing-fluid cartridge than to the electrical interface in the insertion direction.
US11020977B2	Printer and method for controlling printer A printer includes an ink cartridge holding unit that holds a plurality of ink cartridges each including an ink pack and an IC chip that stores ink information, and an access unit that performs wireless communication with the IC chip of the ink cartridges held by the ink cartridge holding unit, and a printer controller, in which the IC chip stores a chip ID, and the printer controller acquires the chip ID from the IC chip of each of the plurality of ink cartridges, and executes, based on the chip ID that is acquired, processing related to the ink information with the IC chip of each of the plurality of ink cartridges.
US11020976B2	Supply authentication via timing challenge response In an example implementation, a print supply cartridge comprises a microcontroller to receive a timing challenge and enable authentication of the cartridge by providing a challenge response. The challenge response is provided in a challenge response time that falls within an expected time window.
US11020974B2	Connection arrangements A connection arrangement is between first and second members pivoted together between open and lockable positions. The first member has a first connector and the second member has a second connector, said connectors being adapted to connect by linear movement between them. The first member has a user-actuatable handle adapted, when the first and second members are in said lockable position: during a first movement of the handle, to engage a latch member of the first member with a catch on the second member; and, during a second movement, to move the first and second connectors with respect to one another in a first linear direction between a disengaged and an engaged position of the connectors. A block element on the first member is arranged to prevent said first and second movements of the handle when said first and second members are not in said lockable position. A block-unlock element on the second member is arranged to displace the block element to enable said first and second movements of the handle when the first and second members are moved from said open position to said lockable position.
US11020973B2	Piezoelectric device, liquid ejecting head, liquid ejecting apparatus, and manufacturing method of piezoelectric device Provided is a piezoelectric device including: a substrate (10) on which a plurality of recesses (12) are provided; a vibrating plate (50) which is provided on one surface side of the substrate; and a piezoelectric element (300) which is provided over the vibrating plate (50) and on which a first electrode (60), a piezoelectric layer (70), and a second electrode (80) are laminated from the substrate (10) side, in which the first electrode (60) is formed to have a first width which is smaller than a dimension of the recess in a parallel arrangement direction in the parallel arrangement direction of at least one recess (12), and the piezoelectric layer (70) is extended to the outer side of the first electrode (60) in the parallel arrangement direction and has a second width which is greater than the first width and smaller than a width of the recess (12) in the parallel arrangement direction, the vibrating plate (50) contains a zirconium oxide layer (52), and when an area of the zirconium oxide layer (52) corresponding to the first electrode having the first width is set as a first area (p), areas of the zirconium oxide layer (52) corresponding to areas where the piezoelectric layer (70) is provided on the outer side of the first area (p) in the parallel arrangement direction are set as second areas (q), and areas of the zirconium oxide layer (52) corresponding to the recess (12) on the outer side of the second areas (q) in the parallel arrangement direction are set as third areas (r), the zirconium oxide layer (52) contains particulate crystal in the first area (p) at least on the first electrode (60) side in the thickness direction and contains columnar crystal in the third areas (r).
US11020972B2	Liquid discharge head There is provided a liquid discharge head including: an individual channel member including individual channel rows; a first common channel member including first common channels and a first partitioning wall, and a damper joined to the first common channel member with adhesive. The damper has first portions that are elastically deformable and overlap with the first common channels and a second portion joined to the first partitioning wall and connected to the first portions. The second portion is thicker than the first portions.
US11020970B2	Liquid ejecting head, liquid ejecting apparatus, and method of manufacturing liquid ejecting head A liquid ejecting head including nozzles ejecting a liquid, a flow path member including flow paths that communicate with the nozzles, and an electric substrate stacked on the flow path member in a first direction. The flow path member includes pipes that protrude in the first direction from a surface facing the electric substrate, the flow paths respectively being formed inside the pipes. Through holes through which the pipes are inserted are provided in the electric substrate. The through holes include a first through hole and a second through hole. The pipes include a first pipe that includes a first contact surface that contacts an internal circumferential surface of the first through hole and a second pipe that includes a second contact surface that contacts an internal circumferential surface of the second through hole.
US11020969B2	Liquid ejection head A liquid ejection head includes pressure chambers arranged in a first direction, first communicating portions, a first common channel extending in the first direction, second communicating portions, a second common channel extending in the first direction, and a damper film. The second common channel includes a first portion and a second portion connecting the first portion and the second communicating portions. The second portion extends from the first portion in a second direction orthogonal to the first direction toward the pressure chambers and is located to a side of the first common channel opposite to the pressure chambers in a third direction orthogonal to the first direction and the second direction. The damper film is located to a side of the second portion opposite in the third direction to the first common channel.
US11020968B2	Head chip, liquid jet head, liquid jet recording device, and method of manufacturing head chip There are provided a head chip and a method of manufacturing the same, a liquid jet head, and a liquid jet recording device each capable of suppressing a stray capacitance to improve the image quality. The head chip according to an embodiment of the present disclosure is a head chip having an actuator plate adapted to apply pressure to liquid to jet the liquid. The actuator plate includes an obverse surface and a reverse surface, a channel extending in a predetermined direction and having a first opening provided to the obverse surface and a second opening which is provided to the reverse surface and is shorter in length in the predetermined direction than the first opening, and an electrode having an obverse surface side part disposed on a sidewall of the channel on the first opening side, and a reverse surface side part which is disposed on the sidewall closer to the second opening than the obverse surface side part and is one of equal to and larger than the obverse surface side part in size in the predetermined direction.
US11020967B2	Printhead A printhead includes a number of inkjet slivers molded into a moldable substrate. The overmolded inkjet slivers form at least one die. The printhead also includes a number of wire bonds electrically coupling the inkjet slivers to a side connector. The side connector electrically couples the inkjet slivers to a controller of a printing device.
US11020966B2	Liquid ejection head substrate, method of manufacturing liquid ejection head substrate, and liquid ejection head A liquid ejection head substrate including a base including a surface having a first and second heat generation elements, a conductive first covering portion, a conductive second covering portion, an insulating layer disposed between the first heat generation element and the first covering portion, and between the second heat generation element and the second covering portion, a fuse portion, first wiring electrically connected to the first covering portion through the fuse portion, the first wiring electrically connecting the first covering portion to the second covering portion, a terminal electrically connected to the first covering portion and the second covering portion through the first wiring, second wiring, and electric connection portions provided between the fuse portion and the terminal in a current path passing through the first wiring, the electric connection portions parallelly connecting the first and second wiring to each other.
US11020963B2	Fluid particle concentration detection A fluidic die may include at least one fluidic passageway, at least one electrode disposed within the at least one fluidic passageway, and control circuitry to activate the electrode within the fluidic die. An impedance sensed at the electrode corresponds to a particle concentration within the fluid. The control circuitry activates the electrode during a separate pulse group assigned to the activation of the electrode among at least one other pulse group assigned to an activation of at least one fluid actuator within a column group.
US11020961B2	Control method of liquid ejection apparatus A control method of a liquid ejection apparatus including a liquid ejection head, a cap configured to seal a nozzle formation surface, and an ejection failure detector which performs a detection operation of detecting ejection failure of a nozzle, the control method including starting a vibration operation of continuously vibrating the liquid in the nozzle, after a liquid ejection operation is completed, starting the detection operation before a relative moving operation of relatively moving the liquid ejection head and the cap so as to face each other is completed, and stopping the vibration operation after the detection operation.
US11020960B2	Fault tolerant printhead In one example, a fault-tolerant printhead includes an array of fluid actuators. Each fluid actuator includes a fault sensor to detect a faulted fluid actuator and a per-fluid actuator memory to store a fault sensor state of the fluid actuator. The fault-tolerant printhead also includes an interface to read a state of each per-fluid actuator memory.
US11020959B2	Printing apparatus and method of judging nozzle discharge state of printing apparatus A printing apparatus for printing using a printhead including a plurality of nozzles, each configured to discharge ink, and a plurality of sensors, corresponding to the plurality of nozzles, for detecting a discharge state of ink from the plurality of nozzles, judges a discharge state. The apparatus prints, based on print data, an image by driving the printhead under a first drive condition to discharge the ink from the printhead to a first area, discharges ink to a second area different from the first area by driving the printhead, based on inspection data, under a second drive condition different from the first drive condition, and judges a discharge state of each nozzle by monitoring an output from each sensor at a timing of driving the printhead under the second drive condition.
US11020958B2	Foil reel mounting device, supporting module, stamping machine, handling tool and method for loading and unloading a reel of stamping foil A foil reel mounting device for supporting a reel of stamping foil in a supporting module. The device includes a support having a recess to receive an axle of the reel of stamping foil. A retaining element mounted on the support and arranged to move between a closed position, in which the retaining element retains the axle of the reel in the recess, and an open position, in which the retaining element releases the axle of the reel from the recess. The retaining element is biased towards the closed position. Also, a supporting module has at least one foil reel mounting device and a stamping machine includes a supporting module or at least one foil reel mounting device. A method for loading and unloading a reel of stamping foil with such at least one foil reel mounting device is also disclosed.
US11020956B2	Fog development for digital offset printing applications Ink-based digital printing systems useful for ink printing include a photoreceptor layer configured to receive a layer of liquid immersion fluid. The liquid immersion fluid includes dampening fluid, dispersed gas particles, and charge directors that impart charge to the solid particles. The photoreceptor surface is charged to a uniform potential, and selectively discharged using an ROS according to image data to form an electrostatic latent image. The charged liquid immersion fluid adheres to portions of the photoreceptor surface according to the electrostatic latent image to form a fountain solution image. The fluid portion of the fountain solution image can be partially transferred to an imaging member and/or transfer member to form a dampening fluid image, either or both of which may be electrically biased. The dampening fluid image is inked on the transfer member, and the resulting ink image transferred to a print substrate.
US11020955B2	Control of solidification in laser powder bed fusion additive manufacturing using a diode laser fiber array A method of method of forming or repairing a superalloy article having a columnar or equiaxed or directionally solidified or amorphous or single crystal microstructure includes emitting a plurality of laser beams from selected fibers of a diode laser fiber array corresponding to a pattern of a layer of the article onto a powder bed of the superalloy to form a melt pool; and controlling a temperature gradient and a solidification velocity of the melt pool to form the columnar or single crystal microstructure.
US11020952B2	Device and method for bonding substrates A method for bonding a contact surface of a first substrate to a contact surface of a second substrate comprising of the steps of: positioning the first substrate on a first receiving surface of a first receiving apparatus and positioning the second substrate on a second receiving surface of a second receiving apparatus; establishing contact of the contact surfaces at a bond initiation site; and bonding the first substrate to the second substrate along a bonding wave which is travelling from the bond initiation site to the side edges of the substrates, wherein the first substrate and/or the second substrate is/are deformed for alignment of the contact surfaces.
US11020951B2	Device and method for bonding substrates A method for bonding a contact surface of a first substrate to a contact surface of a second substrate comprising of the steps of: positioning the first substrate on a first receiving surface of a first receiving apparatus and positioning the second substrate on a second receiving surface of a second receiving apparatus; establishing contact of the contact surfaces at a bond initiation site; and bonding the first substrate to the second substrate along a bonding wave which is travelling from the bond initiation site to the side edges of the substrates, wherein the first substrate and/or the second substrate is/are deformed for alignment of the contact surfaces.
US11020950B2	Device and method for bonding substrates A method for bonding a contact surface of a first substrate to a contact surface of a second substrate comprising of the steps of: positioning the first substrate on a first receiving surface of a first receiving apparatus and positioning the second substrate on a second receiving surface of a second receiving apparatus; establishing contact of the contact surfaces at a bond initiation site; and bonding the first substrate to the second substrate along a bonding wave which is travelling from the bond initiation site to the side edges of the substrates, wherein the first substrate and/or the second substrate is/are deformed for alignment of the contact surfaces.
US11020945B2	Multilayer structure, and packaging material formed from the multilayer structure A multilayer structure is provided, which includes a layer containing a saponified ethylene-vinyl ester copolymer, and a layer of a thermoplastic resin other than the saponified ethylene-vinyl ester copolymer provided on at least one side of the saponified ethylene-vinyl ester copolymer-containing layer with the intervention of an adhesive resin layer. An interface layer having a thickness (X) of 50 to 400 nm is present in an interface between the saponified ethylene-vinyl ester copolymer-containing layer and the adhesive resin layer. Alternatively, a viscosity increase rate in the interface between the saponified ethylene-vinyl ester copolymer-containing layer and the adhesive resin layer is 0.1% to 8%. Therefore, the multilayer structure has long-run durability, and is less liable to have poor appearance even if being produced by a multilayer coextrusion method.
US11020944B2	Delamination-resistant heat-shrinkable multilayer oxygen barrier film containing polyester A first multilayer shrink film has an outer polyester layer, an inner O2-barrier layer, and a tie layer between the polyester layer and the barrier layer. A second multilayer film an outer polyester layer, an inner polyamide layer, and a tie layer between the polyester and polyamide layers. The tie layer comprises a styrene-based polymer, and the tie layer in the second film comprises an anhydride functional styrene based copolymer. Included are a packaging article comprising the film, a packaging process utilizing the film, a process for making the film, and a packaged product comprising a packaging article made the film, with a product inside the package.
US11020942B2	Laminate, multilayered structure, and method for producing the same Provided are: a laminate having an outer surface thereof that is highly adhesive to a rubber material, and having sufficient gas barrier properties, interlayer adhesiveness and flex resistance; a multilayered structure including such a laminate; and a method for producing the same. A laminate including: a plurality of gas barrier layers (A) formed from a polymer including a gas barrier resin; and an elastomer layer (B) including at least one adhesive layer (B1), wherein a sum of number of the gas barrier layers (A) and number of the elastomer layer (B) is 5 or greater and 300 or less, the adhesive layer (B1) is laminated as at least an outermost layer, and the adhesive layer (B1) includes a styrene elastomer and is formed from a polymer having an iodine value of 200 or greater and 300 or less.
US11020939B2	Nanofiber electrodes, fabricating methods and applications of same Nanofiber electrodes for electrochemical devices and fabricating methods of the same are disclosed. In one embodiment, the method includes forming a liquid mixture containing a catalyst, a first polymer of perfluoro sulfonic acid and a second polymer of polyethylene oxide, the first polymer of perfluoro sulfonic acid being pre-treated to remove protons in the first polymer by exchange with a cation species like Na+; and electro spinning the liquid mixture to generate electro spun fibers and deposit the generated fibers on a collector substrate to form a fiber electrode mat comprising a network of fibers, where each fiber has a plurality of particles of the catalyst distributed thereon.
US11020933B2	Friction reduction for engine components The present invention relates to techniques for lowering friction between moving surfaces of, for example, an internal combustion engine. Friction reduction is achieved by adding texture modifications to surfaces that come in contact with each other. Texture modifications that reduce friction in accordance with the present invention include dimples of varying geometries and depths ion the surfaces of components. The present invention also relates to the fabrication technique for applying the texture to the surfaces. In another embodiment, the patterned soft mask is applied onto a large surface (flat or curved including cylindrical rollers surfaces) to be followed by electrochemical etching to imprint the textures onto the component And, in another embodiment, a diamond-like-carbon (DLC) film may be applied to the turbine component to also reduce friction.
US11020932B2	Tip bonded formed laminates of film Tip bonded formed laminates, and methods for making tip bonded formed laminates, are made from multiple layers of formed substrates made from films which are bonded together at the tips of their formed protrusions. Tip bonded laminates can be designed with greater resistance to bending, improved resilience to compression, and can be patterned for directionally oriented responses to tensile loads. Also, tip bonded formed laminates made from multiple layers of formed substrates can use their layered structure to provide better aesthetics as well as better physical properties such as improved puncture resistance. Tip bonded formed laminates can be configured with thicker portions and designed patterns, which are appealing to consumers. A tip bonded formed laminate can be made from two or more formed substrates and can be used instead of a single, thick, unformed, substrate, so the laminate can use about the same amount of material, while still providing surprising functional benefits. Tip bonded formed laminates can provide these benefits without relying on more expensive polymers and/or high concentrations of additives and offer significant improvements at a reasonable cost, when compared with unformed, single layer substrates.
US11020928B2	Removal apparatus and rotary press A removal apparatus for removing pellets from a die plate of a rotary press comprises a housing and a first channel positioned on the housing and configured to receive pellets removed from the die plate. A guide element is arranged on the housing and positioned over the die plate. The guide element is configured to guide pellets produced in the rotary press from the die plate into the first channel. The guide element and the first channel are moveably mounted on the housing. A plurality of mechanical positioning elements are configured to be alternatively inserted into the housing and cooperate with the guide element and the first channel to movably position the guide element and the first channel relative to the housing. Each of the mechanical positioning elements defines a different position of one of the guide element and the first channel relative to the housing.
US11020923B2	Portable electro-pneumatic aluminum beverage can crusher An apparatus for crushing aluminum beverage cans, including; a containment structure with an integral crushing chamber, a pneumatic crushing cylinder with a hub type crushing head which ensures the can remains inside the crushing chamber during the crushing event, an ejection cylinder with an ejection ram, solenoid control valves, a safety interlock switch and a 3 position control switch, an air/gas supply and distribution system and an electrical control system. Two pneumatic cylinders; which are supplied air via two 3-way solenoid control valves, are used to perform the crushing and ejection work. Simultaneous two handed switch operation is required to energize either of the 3-way solenoid control valves to route air to the pneumatic cylinders. Two handed switch operation ensures that the operator's hands are free of the crushing chamber during operation.
US11020919B2	Tire vulcanization mold, tire vulcanization device, and tire production method A tire vulcanization mold disclosed herein includes sectors 13 divided in a tire circumferential direction and molding a tread portion 1, and a pair of upper and lower side plates 11 and 12 molding a sidewall portion 2 of a tire. Mold parting lines 16a and 17a formed by the sectors and the side plates are located in the tread portion 1. A lateral groove molding rib 18 molding a lateral groove 5 in the tread portion is provided to bridge from the sectors 13 to the side plates 11 and 12 and a protrusion molding recess 18a used to mold a protrusion 5a at a groove bottom of the lateral groove 5 is provided to the lateral groove molding rib 18. Mold parting planes 16 and 17 are provided to divide the lateral groove molding rib 18 at a position where the protrusion molding recess 18a is provided.
US11020916B2	Optical fiber cable and method for manufacturing the same An optical fiber cable includes a plurality of optical fibers arranged in juxtaposition with one another, and a plurality of adhesive materials spaced-apart disposed on the optical fibers. Each of the adhesive materials binds adjacent ones of the optical fibers to one another in a number that is smaller than a total number of the optical fibers. A method for manufacturing the optical fiber cable includes arranging the optical fibers in juxtaposition with one another, and applying the adhesive materials to the optical fibers in a spaced-apart manner, such that each of the adhesive materials binds adjacent ones of the optical fibers.
US11020915B2	Extended sealing gels, process for production therof and use therof in sealing compounds for self-sealing tyres A sealing compound comprising an inventive extended sealing gel, a process for producing this sealing compound, the use of sealing gels in sealing compounds, and the use of sealing gel-containing sealing compounds in tyres
US11020914B2	Tridirectional laid scrims for reinforcement purposes A triaxial laid scrim includes a first, second and third set of continuous fibers. The fibers of each set are regularly spaced apart and are parallel to each other. The fibers of the first set are parallel to the warp direction or to the weft direction of the scrim. The fibers of the second set and the third set are oriented symmetrically to each other, respectively at an angle of 30°-80° with respect to the fibers of the first set. Distances between the fibers of the second set and the fibers of the third set are identical. The fibers of the second set cross the fibers of the third set at the intersection thereof with the fibers of the first set, thereby defining regular openings having an isosceles triangle shape. The fibers are coated and attached to each other by a coating that does not fill-up the triangle-shaped openings.
US11020911B2	System and method for assembling a pressure unit with a container A new method for fully automatically manufacturing a fluid container with a pressure unit is described, which pressure unit is mounted in a fluid container. In a station the high-pressure container of the pressure unit is mounted with the closure and the bottom part and is clamped at the upper and lower ends by clamping means and is rotated by rotating means associated with the clamping means. The rotating pressure unit is welded by first laser means and by second laser means, whereas the laser beam of the first laser means being directed to a first joint area of the bottom part of the pressure unit with the container, and the laser beam of the second laser means being directed to a second joint area of the bottom part of the pressure unit with the container, which first and second joint area are separated at a distance to each other.
US11020906B2	Three-dimensional laminating and shaping apparatus, control method of three-dimensional laminating and shaping apparatus, and control program of three-dimensional laminating and shaping apparatus A three-dimensional laminating and shaping apparatus capable of measuring the quality of a three-dimensional laminated and shaped object in real time during shaping of the three-dimensional laminated and shaped object includes a material ejector that ejects the material of the three-dimensional laminated and shaped object onto a shaping table on which the three-dimensional laminated and shaped object is shaped, a light beam irradiator that irradiates the ejected material with a light beam, a data acquirer that acquires monitoring data used to monitor a shaping state of the three-dimensional laminated and shaped object during shaping of the three-dimensional laminated and shaped object, and a shaping quality estimator that estimates shaping quality of the three-dimensional laminated and shaped object based on the monitoring data.
US11020903B2	Apparatus for additively manufacturing of three-dimensional objects An apparatus (1) for additive manufacturing of three-dimensional objects (2) by successive, selective layer-by-layer exposure and thus solidification of construction material layers of a construction material (3) that can be solidified by means of a laser beam (5) generated by a laser beam generation device (4), comprising:—a laser beam generation device (4) provided for generating a laser beam (5) with beam properties defined by at least one laser beam parameter, especially a beam profile defined by at least one laser beam parameter;—a modulation device (9) assigned to the laser beam generation device (4) provided for purposefully changing at least one laser beam parameter that influences the beam properties, especially the beam profile, of the laser beam (5) generated by the laser beam generation device (4) on the basis of a target value that is or can be specified, especially by a user.
US11020897B2	Additive manufacturing yield improvement An additive manufacturing apparatus having a container for holding a radiation-curable liquid, and a build platform having a build surface for holding a product being manufactured during a manufacturing process. The build platform is movable relative to the container in a predetermined direction. The apparatus also includes a radiation source for providing hardening radiation to selectively solidify radiation-curable liquid in the container by exposure to form the product. The container includes an interior floor having a flexible floor part maintainable in a planar configuration in which the flexible floor part is planar. A radiation-curable liquid in contact with the interior floor is confined by a container wall having a flexible wall section arranged to move intactly with the flexible floor part. The apparatus includes a deformation system configured to cause a displacement of at least a part of the flexible floor part in a direction having a component normal to and pointing away from the build surface of the build platform.
US11020895B2	Direct-writing polyimide additive manufacturing material and preparation method thereof A method for preparing a direct-writing polyimide additive manufacturing (AM) material includes (1) conducting ultraviolet curing immediately after the photosensitive polyimide ink is subjected to direct-writing extrusion, to obtain a polyimide precursor formed member; and (2) heat-treating the polyimide precursor formed member obtained in step (1) to obtain the direct-writing polyimide AM material. The direct-writing polyimide AM material obtained by using the method of the present invention has excellent comprehensive properties.
US11020886B2	Method for producing thin-walled small plastic parts and thin-walled small plastic parts A method is disclosed for producing thin-walled small plastic parts having an average wall thickness of less than about 1.5 mm, wherein the small plastic parts are produced in a plastic injection-molding method from polyethylene furanoate (PEF) having a viscosity of, for example, 0.3 dl/g to 0.7 dl/g, for example, preferably less than e.g., 0.6 dl/g, measured according to a measurement method as per ASTM D4603, which polyethylene furanoate has an exemplary water content of less than 100 ppm in the plastic injection process.
US11020884B2	Manufacturing process of a solid thermal balancing composite material A solid thermal balancing composite material with lightweight is formed by a reinforced composite material pressured by a molding machine after going through a powder filling equipment. The reinforced composite material is a mixture of inorganic filler powders and polymer adhesives after granulation. The specific gravity of the solid thermal balancing composite material is no greater than 2.0. In addition, the present invention is adjustable in different shapes for various applications of heat dissipation.
US11020881B2	System and method for pressure control of tire curing press A system for maintaining low pressure within a tire press bladder when the press is open and controlling pressure by using an orifice on the supply line side of the tire press bladder. The supply line runs from a high-pressure supply media to a tire press bladder. A three-way valve alternates in directing high pressure directly through the supply line and directing high pressure to an orifice. Simultaneously the pressure in the bladder is controlled by a regulating valve on the drain side piping. When the press is closed on a tire, the three-way valve supplies high pressure from the supply line directly to the tire press bladder.
US11020880B2	Mold and method for forming a molded part A mold includes a first mold portion, a second mold portion, and a projection. The second mold portion is secured against the first mold portion along a draw axis to form at least one mold cavity. The second mold portion includes an internal surface oriented at an oblique angle relative to the draw axis. The projection extends from the internal surface along a projection axis. The projection forms an elongated profile including a first end, a second ends, and a pair of side surfaces extending between the first end and the second end.
US11020877B2	Base for manual ceramic cutters A base for manual ceramic cutters, which is provided with a support surface for the ceramic parts to be cut, the base including a rigid profile in the central longitudinal area, which rigid profile is secured to the supports of longitudinal displacement guides for a tool-holder head; and two lateral platforms mounted on the rigid profile by longitudinal shafts, which lateral platforms can be lowered between a horizontal use position, in which they form a support surface for the ceramic parts to be cut, and an inoperative position, in which the base defines a smaller surface area.
US11020876B2	System and method for conveyor rack and elevator A system and method for manufacturing a set of cast stones includes a set of spray stations, a set of fill stations, a set of vibration tables, a drying rack, and a demolder connected to the drying rack. A controller is connected to each of the set of spray stations, the set of fill stations, the set of vibration tables, the drying rack, and the demolder, each of which has a set of sensors connected to the controller. The set of spray stations include a set of release stations and a set of color stations. A mold is sprayed with a release product, a set of colors, and then filled with a cementitious material. Once vibrated, the cementitious material is dried to form the set of cast stones, which is then automatically released from the mold utilizing the demolder.
US11020872B2	Miter saw A miter saw includes a base, a table pivotally coupled to the base about a miter axis, a saw unit coupled to the table for movement with the table about the miter axis, and a fence having a stop protruding from a rear surface thereof that is engageable by the table and/or the saw unit to limit miter angle adjustment of the saw unit.
US11020870B2	Apparatus for slabbing rolls of tissue An unlaid slabbing apparatus capable of profiling a roll of tissue material by determining the diameter, circumference, and weight of the roll. The slabbing apparatus calculates the amount of material to be removed based on operator input and predetermined parameters of weight, diameter, and density.
US11020863B1	Locking device for a folding knife A folding knife having an improved locking mechanism that keeps the knife in open extended use position until specific close actions are initiated. The improved locking mechanism provides a safety pin that is secured within the frame element so as to be positioned between the knife blade and the free end of the locking bar that is spring urged there against imparting movement force transfer locking structure thereto with wear adjustable pivot engagement points of locking mechanism under spring urged locking engagement.
US11020859B2	Integrated robotic system and method for autonomous vehicle maintenance A robotic system includes a controller configured to obtain image data from one or more optical sensors and to determine one or more of a location and/or pose of a vehicle component based on the image data. The controller also is configured to determine a model of an external environment of the robotic system based on the image data and to determine tasks to be performed by components of the robotic system to perform maintenance on the vehicle component. The controller also is configured to assign the tasks to the components of the robotic system and to communicate control signals to the components of the robotic system to autonomously control the robotic system to perform the maintenance on the vehicle component.
US11020858B2	Lifting robot systems Lifting robot systems and methods for operating the same are disclosed. A lifting robot system includes a sensor device and a robot device. The robot device includes a body, a lifting component movably coupled to the body, and a collection tray coupled to the lifting component. Upon receiving a command to lift an object, the sensor device automatically detects the object, the robot device places the object on the collection tray, and the robot device causes the lifting component to lift the collection tray from a first height to a second height.
US11020857B2	Robot distance measuring method, apparatus and robot using the same The present disclosure provides a robot distance measuring method and apparatus as well as a robot using the same. The method includes: obtaining a plurality of relative position parameters of a robot from a plurality of ranging sensors; determining an installation distance between each two of the ranging sensors based on the plurality of relative position parameters; determining a sum of the installation distance of each looping arrangement of the plurality of ranging sensors based on the installation distance between each two of the ranging sensors; and enabling the plurality of ranging sensors sequentially to perform obstacle ranging according to a preset looping rule. Since the adjacent ranging sensors are avoided to range simultaneously or sequentially, the interference of the adjacent ranging sensors can be minimized, the accuracy of measuring the distance of the surrounding obstacles can be improved, thereby improving the navigation performance of the robot.
US11020855B2	Storage device, mobile robot, storage method, and storage program Provided is a storage device including: a first storage region comprising a plurality of sensor regions for the plurality of the sensors; a second storage region into which a data set is written, the data set being generated by reading, from the respective plurality of sensor regions, sampling data of a sensor having a longest sampling period among the plurality of sensors for one period and sampling data of other sensors for a period corresponding to the period in which the sampling data of the sensor for the one period is generated and integrating the sampling data; and a control unit configured to write the sampling data of the plurality of sensors into the plurality of sensor regions, respectively, in a ring buffer format and generate the data set at a predetermined timing and write the data set into the second storage region in the ring buffer format.
US11020849B2	Handheld tool case A handheld tool case including at least one base unit, which includes at least one side wall, and at least one cover unit, which is intended to indirectly or directly delimit, with the base unit, a case interior for the storage and/or transportation of at least one transportation object. It is provided that the handheld tool case includes a positioning unit, which, in at least one operating state, during a closing movement between the base unit and the cover unit, converts a closing force into a positioning force on the at least one transportation object, which has at least one component in the direction of the side wall.
US11020848B2	Ergonomic trough-support system A trough-support system includes a trough, an arm rest and a handle. In some embodiments, the body of the arm rest is designed to curve around the arm of a user. The arm rest and handle can include one or more magnetic tool holders that can hold a tool or instrument. The handle can include a strap with a magnetic tool holder that can hold a tool or instrument. Various parts of the arm rest, handle and/or strap can be made of magnetic material to hold tools.
US11020844B2	Hand-held power tool including a mode-setting unit In a hand-held power tool including a gear for driving an output shaft, which is situated in an assigned gear housing, and including a mode-setting unit for setting the operating mode for an impact drilling mode, a drilling mode, or a screwing mode, the mode-setting unit including a rotatable actuating element and a rotatable setting element coupled to the rotatable actuating element. The setting element is coupled, at least in one operating mode, to a transmission element which is mounted on the gear housing and is axially displaceable on the gear housing in a screwing position assigned to the screwing mode and is axially fixed on the gear housing in impact drilling and drilling positions assigned to the impact drilling and drilling modes. The actuating element and the setting element are formed as one piece from plastic.
US11020843B2	Tool and tool attachment A tool for fastening an insulator to a support, the insulator including an insulator body having a front and back, a formation for supporting a barrier, and at least one mounting formation having a front and a back by which the insulator is attached to a support, the back of the mounting formation in use being proximal to the support, at least one of the at least one mounting formation including at least one passage extending transversely through the mounting formation from the front to the back of the mounting formation, and at least one alignment member, the tool including a driver blade for driving a staple, and at least one passage alignment member, in use the at least one passage alignment member aligning at least one passage of the insulator, with one leg of a staple.
US11020842B2	Jig assembly for laser welding A jig assembly for laser welding includes a jig body having a first penetration portion through which laser light for welding is capable of passing; a contact member connected to the jig body to contact a welding target, the contact member having a second penetration portion through which the laser light passing through the first penetration portion is capable of passing toward the welding target; a tilting unit having a hinge structure to connect the jig body and the contact member to each other; and an elastic member interposed between the jig body and the contact member to apply an elastic force to provide close contact between the contact member and the welding target.
US11020839B2	Apparatus of supplying slurry for planarization process and chemical-mechanical-polishing system including the same An apparatus of supplying slurry for a planarization process includes a housing having a first side and a second side and channels extending through the housing from the first side to the second side along a first direction. The channels include a first channel connecting a first inlet on the first side and a first outlet on the second side, a second channel connecting a second outlet on the first side and a second inlet on the second side, a third channel connecting a third inlet on the first side and a third outlet on the second side, and a fourth channel connecting a fourth outlet on the first side and a fourth inlet on the second side. An intermediate portion of the second channel crisscrosses an intermediate portion of the third channel along a second direction crossing the first direction.
US11020837B2	Monolithic platen In an embodiment, a chemical mechanical planarization (CMP) system includes: a monolithic platen within a platen housing, wherein the monolithic platen is formed of a single piece of material, wherein the monolithic platen includes: a first portion within a first opening, and a second portion within a second opening, wherein the first portion has a different diameter than the second portion; and a polishing fluid delivery module above the monolithic platen, wherein the polishing fluid delivery module is configured to deliver slurry to the monolithic platen during performance of CMP.
US11020836B2	Device for automatically changing grinding discs A device (1) for automatically changing sanding discs (12) includes a stacking device (10) for a plurality of grinding discs (12) and a guide element (16) for orienting the suction openings (32) in the grinding discs (12) along a common central axis (18), wherein the guide element (16) is arranged eccentrically with regard to the central axis (18). A positioning element (17) is provided for positioning a tool head of a grinding device, wherein the positioning element (17) and the guide element (16) are mounted in a floating manner. A device (1) for automatically changing grinding discs (12) includes a detachment device (50), wherein the detachment device (50) has a bearing surface (51) for a grinding-disc receptacle. The bearing surface (51) has an opening (52), the diameter of which is greater than the diameter of the grinding disc (12). A separating element (53) is arranged above the opening (52). A system includes a device (1) for automatically changing grinding discs (12) containing a stacking device (10) and a detachment device (50).
US11020827B2	Torsion bar active length control and method of manufacturing A torsion bar includes a central portion extending in an axial direction about a longitudinal axis. The torsion bar also includes a first end portion having a splined outer surface, the first end portion disposed proximate a first end of the torsion bar, the first end portion spaced from the central portion with a first annular groove extending circumferentially about the torsion bar.
US11020826B2	Repair system and method for repairing cavitation damage for a fuel pump A method for repairing damage to a fuel pump assembly of a locomotive is provided that includes identifying a void within a fluid cavity of a fuel pump assembly. After identifying the void within the fluid cavity of the fuel pump assembly, the void is cleaned with a cleaning product, and a filler material is inserted within the void. Then the filler material is laser welded to repair the void. After being laser welded, the fluid cavity of the fuel pump assembly is honed.
US11020823B2	Laser diode driving power source and laser machining device A laser diode driving power source of a laser machining device that radiates laser light emitted from an LD to a workpiece to machine the workpiece includes a power converter including a switching device, to supply a current to the LD, and a control unit to control a switching operation of the switching device. A value smaller than a value that is n times a time constant for laser machining is set as a switching period of the switching device in the control unit, the n is larger than 1, and the time constant for laser machining is a value obtained by dividing a surface roughness required for machining of the workpiece by a moving velocity of the workpiece.
US11020818B2	Connection element for an interlocking connection to at least one component A connection element for an interlocking connection to at least one component includes at least one component held between the connection element and a securing element wherein the connection element and the securing element enter into a friction welded connection, having a head with a drive and a shaft having at least two cutting structures on a front side. The at least two cutting structures have cutting edges situated in a cutting plane, wherein the cutting plane borders the shaft, and the at least two cutting structures are also spaced apart in the circumferential direction and define a cutting diameter. A cross-section of the shaft has a reduced extension between the cutting structures relative to the cutting diameter, wherein the area of the reduced extension extends in the axial direction at least with the length of the cutting diameter from the cutting structures in the direction of the head.
US11020816B1	Methods of forming a friction stir weld between a steel piece and an aluminum piece, and related assemblies Described are methods for forming a friction stir weld between a steel piece and an aluminum piece, with specific examples of the steel piece and the aluminum piece being a cover and a base of an enclosure.
US11020812B1	Welding lead connector and welding lead connector including locking mechanism A male welding lead connector apparatus including a slidable member to block the male welding lead connector from rotating relative to a female welding lead connector when the two connectors are engaged with one another. A method of locking a male welding lead connector to a female welding lead connector using a special male welding lead connector including a slidable member to block the male welding lead connector from rotating relative to a female welding lead connector when the two connectors are engaged with one another.
US11020809B2	Machining jig and processing method A machining jig holds a workpiece with respect to a tool when machining the workpiece with the tool, the workpiece including a ridge that projects from an outer periphery of a cylindrical section in a radial direction and that extends so as to intersect a peripheral direction. The machining jig includes a holding jig that includes a cylindrical body section that is disposed at an outer periphery of the workpiece and a stopping section that projects inwardly from the body section and that stops a face of a surface of the ridge on a side where the tool leaves a processing portion of the ridge; and a coaxial base that is coaxial with the holding jig and to which the holding jig is coaxially fixed.
US11020807B2	Hole drilling jig apparatus The current invention relates to jig apparatus which is provided of a form to allow accurate positioning and repositioning of the same with respect to workpiece and the use of the jig apparatus to provide a guide for the provision of a drill bit through at least one guide passages therein to form a hole in the workpiece at a required location. In one embodiment the jig apparatus is provided in a form so as to provide a plurality of passages, each of which can be used as a guide for a drill bit to thereby allow a plurality of spaced apart drill holes to be formed in the workpiece without the need to move the jig apparatus with respect to the workpiece. In one embodiment guide means are provided which are selectively positionable by the user in order to allow the position of the jig apparatus with respect to the workpiece to be accurately defined and retained by the user.
US11020804B2	Surface-coated cutting tool and method for manufacturing the same A surface-coated cutting tool includes a substrate and a coating formed on a surface of the substrate, the coating including one or two or more layers, at least one of the layers being an Al-rich layer including hard particles, the hard particle having a sodium chloride type crystal structure, and including a first unit phase in a form of a plurality of lumps and a second unit phase interposed between the lumps of the first unit phase, the first unit phase being composed of a nitride or carbonitride of AlxTi1-x, the first unit phase having an atomic ratio x of Al of 0.7 or more and 0.96 or less, the second unit phase being composed of a nitride or carbonitride of AlyTi1-y, the second unit phase having an atomic ratio y of Al exceeding 0.5 and less than 0.7.
US11020802B2	Methods of controlling nanostructure formations and shapes A method of forming monodispersed metal nanowires comprising; forming a reaction mixture including a metal salt, a capping agent and an ionic additive in a polar solvent at a first temperature; and forming metal nanowires by reducing the metal salt in the reaction mixture.
US11020800B2	Apparatus and methods for sealing powder holes in additively manufactured parts Apparatus and methods for sealing powder holes in additively manufactured parts are presented herein. Powder holes are co-printed to facilitate post processing sealing. Embodiments include co-printed caps, friction welded caps, rivets, silicone plugs, co-printed tangs, multiple micro holes, layup, and spin forming. By using one or more of the above techniques, powder holes can be sealed on additively manufactured parts.
US11020798B2	Method of transferring molten metal The invention relates to systems for transferring molten metal from one structure to another. Aspects of the invention include a transfer chamber constructed inside of or next to a vessel used to retain molten metal. The transfer chamber is in fluid communication with the vessel so molten metal from the vessel can enter the transfer chamber. A powered device, which may be inside of the transfer chamber, moves molten metal upward and out of the transfer chamber and preferably into a structure outside of the vessel, such as another vessel or a launder.
US11020795B2	Method and device for producing foundry ingots from metal The invention relates to a method for producing foundry ingots (1) from metal, in particular from steel, having a cross-sectional area of more than 0.1 m2, wherein liquid metal (2) is discharged into an ingot mold (15) open at the bottom either directly form a casting ladle (11) or via a tundish (12), and wherein, by a drawing piston (28), which is vertically movable in the direction of a longitudinal axis (5) of the foundry ingot (1) and on which the foundry ingot (1) is at least indirectly arranged, the at least partially solidified foundry ingot (1) is drawn from the ingot mold (15) in the direction of the longitudinal axis (5).
US11020791B2	Ceramic pour cup assembly and method of forming such an assembly A pour cup assembly (10) includes a pour cup (12) of frusto-conical shape and which has an inlet end (14), of relatively larger diameter, and an outlet (16), of relatively smaller diameter. The assembly (10) also includes two yokes (18, 20) each including a body section (22) with a part frusto-conical internal profile and opposing arms (24, 26) extending laterally from the body section (22) and that lie in a common plan. Each arm (24, 26) has a bore or hole (30) therein. The body portion (22) has an external profile that is also part frusto-conical in shape and has one or more circumferential grooves (32) in its outer surface. The grooves (32) extend parallel to the arms (18, 20) and transverse to the longitudinal direction of the body portion (22). The grooves (32) in use accommodate a tie element disposed around the body portion (22) and cup (14) to hold the assembly together while the assembly (10) is subsequently coated with ceramic material to form the pour cup assembly. This is typically done at the same time as creating the investment cast around the invested pattern. The arrangement provides a pour cup assembly (10) that can be packaged and transported more efficiently and that can be handled with lifting assistance. The assembly also allows for the use of different sizes of pour cups with the same yokes, making the assembly more versatile.
US11020788B2	Device for jointing a plurality of elements on a shaft A method for jointing elements, each having a cutout, on a shaft by a device for producing a control shaft, comprises disposing the elements vertically above one another, aligned, and fixed. The method also comprises pushing the shaft in vertically from above though the cutouts of the elements by a traversable guide carriage of the device and displacing by a pneumatic piston of the device the traversable guide carriage and the shaft attached thereto until a maximum first press-in force is reached. The method further comprises displacing by at least two spindles of an electric spindle drive of the device the traversable guide carriage and the shaft when the maximum first press-in force is exceeded.
US11020778B2	Photoresist removal method using residue gas analyzer A photoresist removal method is provided. The photoresist removal method includes analyzing the process status of each of a number of semiconductor substrate models undergoing a tested plasma ash process by a residue gas analyzer. The tested plasma ash processes for the semiconductor substrate models utilize a plurality of tested recipes. The photoresist removal method further includes selecting one of the tested recipes as a process recipe based on the analysis results from the residue gas analyzer and at least one expected performance criterion. In addition, the photoresist removal method includes performing a plasma ash process on a semiconductor substrate according to the process recipe to remove a photoresist layer from the semiconductor substrate.
US11020774B2	Microelectronic treatment system having treatment spray with controllable beam size This invention relates to systems and methods that produce a treatment beam with a controllable beam size. This is accomplished by providing an auxiliary chamber in open fluid communication with the main process chamber. A nozzle is mounted in a recessed manner in the auxiliary chamber. The nozzle dispenses a treatment spray into the auxiliary chamber. The auxiliary chamber shapes and dispenses the treatment material as a treatment beam into the process chamber. In illustrative embodiments, control of process chamber pressure adjusts the beam size of a treatment beam used to treat the surface of one or more microelectronic substrates.
US11020773B2	Cleaning devices A cleaning device comprises a housing. The cleaning device also comprises a drive gear that rotates about a drive-gear rotational axis. The cleaning device further comprises driven gears, driven by a drive gear and rotatable about corresponding driven-gear rotational axes inside the housing. The cleaning device further comprises brushes, located outside the housing and each rotatable together with a corresponding one of the driven gears. The cleaning device also comprises a vacuum tube, passing through the drive gear. The cleaning device additionally comprises a solvent supply, passing through the housing.
US11020772B2	System and method for cleaning wind turbine blades and solar panels Embodiments of the present invention are directed to a method for cleaning a wind turbine blade or a solar panel with a wind cinch device. The method includes applying a cleaning solution to a surface of a wind turbine blade or solar panel; affixing a wind cinch device around a high point of the wind turbine blade or solar panel; applying tension to one or more lines attached to the wind cinch device to control the pressure the wind cinch device applies to the surface of the wind turbine blade or solar panel; and applying tension to the one or more lines attached to the wind cinch device to pull the wind cinch device from the high point on the wind turbine blade or solar panel to a low point on the wind turbine blade or solar panel. Other embodiments of the present invention are directed to a Wind Cinch device. The Wind Cinch device includes a main body, the main body being an elongated member having a cleaning surface sufficient in length to form a loop around a wind turbine blade when wrapped around a wind turbine blade. The Wind Cinch device also includes a plurality of rigging points, each rigging point adapted to receive a line. Applying tension to one or more of the lines attached to the rigging points changes the circumference of the loop formed by wrapping the wind cinch device around the wind turbine blade.
US11020770B1	Container chutes for sortation systems Systems, methods, and computer-readable media are disclosed for container chutes for sortation systems. In one embodiment, an example system may include a frame and a chute assembly coupled to the frame, where the chute assembly is configured to pivot from a first position to a second position with respect to the frame. The chute assembly may include a first planar ramp, a first support on a first side of the first planar ramp, and a second support on a second side of the first planar ramp. The chute assembly may include a first pneumatic lift component coupled to the first support and to the frame, and a second pneumatic lift component coupled to the second support and to the frame. The chute assembly may be held in the second position when the first pneumatic lift component and the second pneumatic lift component are in a compressed configuration.
US11020769B2	Nut sorter A nut sorter includes a support frame with a rotatable cage connected thereto. The rotatable cage is comprised of support rings with a plurality of longitudinally extending rods connected thereto. The outer periphery of the longitudinally extending rods extends inwardly into a center space defined by the inner diameter of the support rings. The nut sorter also has a plurality of scrapers utilized to dislodge stuck debris and nuts as the cage rotates under the scrapers.
US11020762B2	Coupling for the connecting of lines, powder coating facility including the coupling, and method for cleaning of the powder coating facility A coupling is provided for the connecting of lines and includes a first coupling disc with first line connectors and a second coupling disc with second line connectors. Moreover, a first drive is provided in order to be able to move the two coupling discs axially with respect to each other. Moreover, a second drive is provided in order to be able to rotate the two coupling discs with respect to each other.
US11020761B2	Piston rod sleeve mounting for fluid sprayer pump A piston rod includes a piston end that is removably attached to the piston rod body. A sleeve extends around the piston rod body and interfaces with a seal disposed within a pump. A ring extends from the piston end defines at least a portion of a socket formed in the piston end for connecting the piston end and the piston rod body. The ring has a cylindrical ring exterior and the sleeve rests on the cylindrical ring exterior such that the shank, the ring, and the sleeve radially overlap each other.
US11020759B2	System for controlling air shaping flow in spray cap of spray tool A system, including a spray cap configured to couple to a spray tool, wherein the spray cap includes a body and an air shaping passage through the body. The air shaping passage includes a flow control passage, an expansion chamber downstream from the flow control passage, and one or more air shaping outlets downstream from the expansion chamber.
US11020755B2	Foam dispensing container A foam dispensing container (100) has a container body (40) that reserves a liquid agent (L); a head part (30) that has an outlet (20), and dispenses the liquid agent (L) delivered from the container body (40) through the outlet (20) into foam; and a pump head part (32) that allows dispensing of a predetermined amount of the foamy liquid agent (foam) through the outlet (20) each time it accepts a user's operation. The outlet (20) is formed with a contiguous geometry narrowed from an intended shape. A foam, dispensed through the outlet (20) as a result of a single or multiple operations of the pump head part (32), is built up into the intended shape in a plan view seen in the dispensing direction.
US11020753B2	Apparatus and method for monitoring and controlling a centrifugal The present invention relates to an integrated apparatus for monitoring the separation of the solid and liquid phases in a centrifugal by measuring at least one parameter of a filling material inside a centrifugal, the integrated apparatus comprising at least one light source for illuminating at least part of a surface of the filling material, and a light detector arrangement being a adapted to receive light reflected from the filling material. The present invention also relates to an associated method for monitoring and controlling separation of solid and liquid phases in a centrifugal.
US11020748B2	Method and apparatus for controlling milling roll machine A method and an apparatus for controlling a milling roll machine capable of accurately monitoring a surface temperature of a roll and preventing a high temperature abnormality occurring on a roll surface from being overlooked are provided A temperature sensor S that monitors surface temperatures of a pair of rolls 4 and 5 and a temperature of a milled product after passing through the rolls is provided in the vicinity of the pair of rolls 4 and 5, and opening/closing control of the gap between the rolls 4 and 5 or flow rate control of the raw material stock is performed according to the surface temperatures of the rolls and the temperature of the milled product after passing through the rolls detected by the temperature sensor S.
US11020741B2	Field portable, handheld, recirculating surface acoustic wave and method for operating the same A system and method for performing a portable, fast, field assay of a small sample biological analyte includes a microfluidic cartridge and a reader with which the microfluidic cartridge is selectively communicated. A closed microfluidic circuit mixes and recirculates the analyte with a buffer. A shear horizontal surface acoustic wave (SAW) detector communicates with the microfluidic circuit and has a plurality of channels including at least one functionalized sensing channel in which the mixed analyte and buffer is recirculated and sensed. Capture of the analyte is amplified by recirculation of the analyte and buffer, and detection is amplified by use of an all-purpose endospore display mass amplification.
US11020734B2	Ion exchange membrane for alkali chloride electrolysis, production method, and alkali chloride electrolysis apparatus To provide an ion exchange membrane for alkali chloride electrolysis which has high membrane strength and low membrane resistance, thereby capable of reducing the electrolysis voltage during alkali chloride electrolysis. In this ion exchange membrane (1) for alkali chloride electrolysis, a reinforcing material 20 formed by weaving reinforcing yarns 22 and sacrificial yarns 24 is disposed in a layer (S) 14, and layer (S) 14 has elution portions 28 formed by elution of at least portions of the sacrificial yarns 24. In a cross section perpendicular to reinforcing yarns of the warp, the average distance (d1) from the center of a reinforcing yarn 22 to the center of the adjacent reinforcing yarn 22, the total area (P) obtained by adding the cross-sectional area of an elution portion 28 and the cross-sectional area of a sacrificial yarn 24 remaining in the elution portion 28, the number (n) of elution portions between adjacent reinforcing yarns 22, and the ion exchange capacity of a layer (Sa) located on the most anode side in the layer (S) 14 during alkali chloride electrolysis, are controlled to be within specific ranges, respectively.
US11020733B2	Honeycomb structure A honeycomb structure includes a pillar-shaped honeycomb structure body having porous partition walls surrounding a plurality of cells which extend from a first to a second end face and which form flow channels of a fluid, and a circumferential wall enclosing the partition walls, wherein, specific cell of the cells is provided with a pair of projection which projects into the cell from the partition wall, the projection projects, in at least a pair of opposed partition walls among the partition walls constituting the cell, into the cell from a first and a second side, and which is provided continuously in a direction the cell extends, and in the case where the width of a top part of the projection is denoted by W1, and the width of a bottom part of the projection is denoted by W2, W1>W2 holds, and W2/W1 is 0.5 to 0.9.
US11020732B2	Catalyst bed and method for reducing nitrogen oxides A catalyst bed comprising a ceramic or metallic foam comprising one or more NOx reduction catalysts is described. A method for reducing the concentration of NOx in a dust containing gas stream comprising: a) passing a first gas stream containing NOx into a contacting zone; b) contacting the first gas stream with a ceramic or metallic foam catalyst bed having one or more flow paths through the catalyst bed wherein the ceramic or metallic foam comprises a NOx reduction catalyst to produce a second gas stream with a reduced NOx concentration; and c) passing the second gas stream out of the contacting zone wherein the first gas stream has a dust concentration of at least 5 mg/Nm3 and the pressure drop of the foam catalyst bed increases by 300% or less relative to the initial pressure drop of the foam catalyst bed due to dust accumulation, measured under the same conditions is also described.
US11020730B2	Halogen-containing metathesis catalysts and methods thereof The present disclosure provides compounds, compositions, and methods for preparing alkenyl halides and/or haloalkyl-substituted olefins with Z-selectivity. The methods are particularly useful for preparing alkenyl fluorides such as CF3-substituted olefins by means of cross-metathesis reactions using halogen-containing molybdenum and tungsten complexes.
US11020727B2	Fe43.4Pt52.3Cu4.3 polyhedron nanoparticle with heterogeneous phase structure, preparing method and application thereof A Fe43.4Pt52.3Cu4.3 heterogeneous phase structure polyhedron nanoparticle, a preparing method and an application as an efficient fuel cell oxygen reduction catalyst are provided. The Fe43.4Pt52.3Cu4.3 heterogeneous phase structure polyhedron nanoparticle, includes: three elements of Fe, Pt and Cu; wherein the Fe43.4Pt52.3Cu4.3 heterogeneous phase structure polyhedron nanoparticle has a heterogeneous phase structure in which face-centered cubic and face-centered tetragonal coexist; wherein the heterogeneous phase structure is a face-centered tetragonal phase shell and face-centered cubic core with a high crystal plane index; a surface of the polyhedron nanoparticle has 1 to 2 atomic layers of enriched with Pt; a diameter distribution of the nanoparticles is at a range of 4.5 to 14.5 nm, and an average size is 8.4 nm. In the invention, hexadecylamine, iron acetylacetonate, copper acetylacetonate, platinum acetylacetonate, and 1,2-hexadecanediol are uniformly mixed, and oleylamine and oleic acid are added, condensed refluxed at 320-330° C.
US11020725B2	Method of preparing superabsorbent polymer A superabsorbent polymer according to the present invention has excellent initial absorption properties, and thus it may be used in sanitary materials such as diapers, etc., thereby exhibiting excellent performances.
US11020715B2	Gas-liquid dissolving apparatus The disclosure provides a gas-liquid dissolving apparatus, comprising: a sealed tank, a gas jet tube and a plurality of membrane plates; the sealed tank being provided with a liquid supply joint at top, and a gas inlet joint and an output joint at bottom; the gas jet tube being located inside the sealed tank and connected to the gas inlet joint; the gas jet tube having a plurality of gas jet holes distributed on tube wall; the plurality of membrane plates being stacked around the periphery of the gas jet tube and fixed; each membrane plate being ring-shaped, and being structured with an inner ring wall, a mixing chamber and an outer ring wall sequentially from the center; the mixing chamber having an opening facing downward, and the inner ring wall being thicker than the outer ring wall, with a gap existing between the two adjacent stacked outer ring walls.
US11020712B2	Polyelectrolyte multilayer (PEM) membranes and their use The present invention relates to a polyelectrolyte multilayer (PEM) membrane comprised of at least one bilayer, wherein the bilayer is comprised of a layer of a polymeric polycation and a layer of a polymeric polyanion. Furthermore, present invention relates to methods for the production of these PEM membranes by layer-by-layer deposition and the use of these PEM membranes for the decontamination of liquids, preferably water.
US11020708B2	Connecting mechanism for a water purification cartridge A connecting mechanism (1) for a cartridge-type replaceable module (2) that has at least one fluid port (2a, 2b) at each of opposite sides of the module (2) in a longitudinal direction of the module (2). The connecting mechanism (1) comprises two connector elements (3) spaced apart in the longitudinal direction of the module (2) and each provided with at least one fluid connector (3b) configured to releasably inter-engage with a complementary fluid port (2a, 2b) of the module (2) at the respective side thereof, wherein at least one of the connector elements (3) is movable to perform a translational movement in the longitudinal direction of the module (2). The connecting mechanism (1) further comprises at least one driver element (4) arranged to engage with the module (2) and with the at least one movable connector element (3) such that a rotational or translational movement of the module (2) engaged with the driver element (4) causes the translational movement of the movable connector element (3) via the driver element (4) to establish/release the inter-engagement of the fluid connector(s) (3b) of that connector element (3) with the associated fluid port(s) (2a, 2b) of the module (2).
US11020707B2	Monolithic separation membrane structure, method for producing monolithic separation membrane structure, and method for dehydrating A monolithic separation membrane structure comprises a support body and a separation membrane. The support body is composed of a porous material and includes a plurality of through holes. The separation membrane is formed in a tubular shape on an inner side of the plurality of through holes, and is used in a penetrative vaporization method or a vapor infiltration method. The helium gas permeation resistance in the support body is less than 8.3×107 Pa·sec/m2.
US11020703B2	Temperature-swing adsorption process A temperature swing adsorption process for removing a target component from a gaseous mixture containing at least one side component besides the target component, said process being carried out in at least one reactor performing the following steps: an adsorption step (a), wherein an input stream of said gaseous mixture is contacted with a solid adsorbent selective for said target component, producing a first waste stream depleted of the target component; a heating step (b) for regeneration of the loaded adsorbent providing a first output stream containing the target component; a cooling step (c) of the regenerated adsorbent, said process also comprising: i) a preliminary heating step (a2) before said heating step (b), wherein a gaseous product containing said at least one side component is released from the adsorbent; ii) recycle of said gaseous product to a further adsorption step (a).
US11020701B2	Filter element having optimized flow control A filter element for an air filter has a filter bellows with a filter medium folded multiple times. A recess is disposed in the filter bellows and is designed to receive a guiding rib of the air filter. The recess is curved at least in sections thereof along a length extension of the recess. The air filter has a housing and a guiding rib, wherein the filter element is arranged at least partially in the housing and the guiding rib is immersed at least partially in the recess of the filter element. In a method for producing the filter element, the recess in the filter bellows is formed with a computer-assisted separation method that forms the recess to be curved at least in sections thereof.
US11020699B2	Air filter arrangement; assembly; and, methods Air filter cartridges are disclosed. Also described are air cleaners including the filter cartridges. Methods of assembly and use are also provided. Also, systems of use are described.
US11020694B1	Mobile oil filtration system and method of use A mobile oil filtration system includes a mobile oil reservoir having a plurality of wheels; a housing secured to the mobile oil reservoir; an input conduit secured to the housing; a pump in fluid communication with the input conduit; a spring-loaded filter downstream from and in fluid communication with the pump; a bag filter downstream from and in fluid communication with the spring-loaded filter; and an output conduit secured to the housing and in fluid communication with the bag filter.
US11020691B2	Pipe cap for drain pipe outlet An apparatus restricts access to an above-ground conduit outlet extending from an exterior wall of a building. The access restricting apparatus comprises a pipe cap defining a fluid passage open at both a proximal end and a distal end. The proximal end of the pipe cap is adapted to be connected in fluid communication with the conduit outlet. A screen is disposed across the opening at the distal end of the pipe cap for enclosing the interior fluid passage of the pipe cap within an enclosed space defined at least partially by the screen. Apertures in the screen restrict access to the conduit outlet of items larger than the apertures.
US11020688B2	Enclosed media fluid filtration device A filtration device comprising a media basket, a baseplate, and a canister. The media basket is affixed to the baseplate. The canister has a cavity therein and is detachably coupled with the baseplate to enclose the media basket. The media basket contains a porous filtration material that efficiently removes contaminants from liquid. The device is configured to establish a first siphon to convey liquid from outside the device into the canister cavity through a canister pipe when a liquid level outside the filtration device is higher than the top of the weir in the canister pipe and configured to establish a second siphon to convey liquid from canister cavity through the top of a center riser pipe and out an outlet pipe when the first siphon has been established and the liquid level outside the filtration device is higher than the top of the center riser pipe.
US11020683B2	Building block and building block kit A building block includes at least one of a plug portion and a socket portion. The plug portion has two cantilevered tongues deflectable toward each other. Each cantilevered tongue includes a first engaging portion. The socket portion defines a chamber and has two second engaging portions. The plug portion and the socket portion are configured in such a way that the plug portion of one building block is insertable into the chamber of the socket portion of another building block, and the two cantilevered tongues of the building block deflect toward each other after insertion of the plug portion of the building block into the chamber of the socket portion of the other building block, which allows the first engaging portions of the building block to be engaged with the second engaging portions of the other building block, thereby connecting the two building blocks together.
US11020682B2	System and method for connecting magnetic building tiles A base member configured for use with a windowed magnetic tile, the base member including a tile portion having three or more outer edges configured with respective protrusions for fitting engagement with respective notches on corresponding three or more inner edges of the windowed magnetic tile; a first projection extending outwardly from a first surface of the tile portion formed by the three or more outer edges; and a first opening disposed on the first projection.
US11020681B2	Super fold playhouse Embodiments relate generally to a foldable play structure comprising a plurality of panels each connected to another by at least one hinge to provide an accordion fold structure, wherein the accordion fold play structure comprises two configurations, in a first configuration, the plurality of panels are folded to be stacked in substantially parallel planes, and in a second configuration, the plurality of panels are unfolded forming a play structure. A method for assembling a foldable structure may comprise providing a playhouse with an accordion fold structure, wherein in a first configuration of the accordion fold structure, the plurality of panels are folded to be stacked in substantially parallel planes, and in a second configuration of the accordion fold structure, the plurality of panels are unfolded forming a play structure; and unfolding the playhouse from the first configuration to the second configuration.
US11020680B2	System and method for providing a toy operable for receiving and selectively vocalizing various electronic communications from authorized parties, and for providing a configurable platform independent interactive infrastructure for facilitating optimal utilization thereof The present invention is directed to a toy, and methodologies and infrastructures for provision, operation, and utilization thereof, implementable in any configuration (plush, stuffed, doll, character, vehicle, etc.) that is operable to: (a) receive an electronic message (optionally inclusive of media and/or interactive content) from an authorized party, (b) provide at least one visual (and/or audio) indicator to a recipient (e.g., a child) that a message is present (e.g., a toy element or region may light up, flash, emit an audio signal), and (c) vocalize the electronic message to the recipient in response to at least one of: (1) one or more specific actions of the recipient (e.g., moving the toy, picking it up, touching the active indicator, a verbal utterance, etc.), and/or (2) detection of proximal presence of a recipient ready for receipt thereof. The inventive toy and related data processing infrastructures may comprise many additional capabilities and functions.
US11020679B1	Rotating flipping and grasping movements in mechanical toys A mechanical toy incorporating structures that coordinate the positioning and movement of specific body parts for rotating, flipping and grasping movements with programmable systems, methods, and devices within toy structures. Extensions connected to opposite sides of a motive body or head assembly including grasping members and support structures for rotating and/or turning actions about a central body portion including grasping appendages. The toy apparatus may also interact with accessory items to enhance play value.
US11020678B2	Comfort-inducing proxy A simulated living entity (SLE) HAS a body formed of cushioned material, a contact area on an surface of the body, a heating panel under the contact area, a microphone positioned proximate one end of the exposed surface, a speaker positioned proximate the microphone, a heartbeat simulator, a breath simulator proximate the microphone and speaker, and a control system within the body comprising a microprocessor, a coupled data repository, a power supply, wireless communication circuitry, and a digital bus. The heating panel heats the contact area, the heartbeat simulator provides feeling and sound of a beating heart, the breath simulator provides air intake and exhaust, and the speaker provides sounds of a person sleeping, synchronized with the breath simulator.
US11020676B2	Backbone rail for a roller coaster and roller coaster arrangement A backbone rail for a roller coaster, comprising two rail pipes designed for vehicles to travel upon, and at least one, particularly main load-bearing backbone pipe not designed for vehicles to travel on, whose second moment of area is greater than the second moment of area of the rail pipes, wherein rail pipes and backbone pipe are connected to each other section-by-section by stiffening bulkheads, whereby at least one bulkhead has the following features: A transverse cross member, which extends in the orthogonal direction and connects the rail pipes with each other, and bulkhead plates, connecting at least one rail pipe with the backbone pipe, wherein at least one bulkhead plate is designed as a longitudinal bulkhead plate, whose main plane of extension extends perpendicular to the bulkhead plane, and which is attached to the backbone pipe in such a way that it runs tangentially into the backbone pipe. In addition, the invention relates to a roller coaster arrangement with such a backbone rail.
US11020673B2	Method for providing battle game, server device, and computer-readable recording medium User-involved battle development with strategic or tactical elements in a game is enabled. A method, implemented in a computer including a control unit, for providing a battle game in which a user repeatedly attacks and defends against an opponent using a plurality of objects placed in a plurality of areas arranged in a matrix, includes: a selection step of causing the user to select an area from the plurality of areas, and holding the area which has been already selected as a selected area; a first execution step of causing an object placed in the selected area, to execute a first action; a determination step of determining whether or not a combination of an already selected area and the currently selected area matches at least one line which is any of a row, a column, and a diagonal of the matrix; and a second execution step of causing an object to execute a second action, in the case where the determination step determines that the combination matches the at least one line.
US11020672B2	GPS tracking with map overlay A game system has one or more network-connected servers executing system software (SSW) on one or more processors from a non-transitory medium, providing virtual reality games for players logged in to the system to select and play, and a plurality of mobile digital devices in use by players logged in to the system, associated by the system with individual player identity, executing a mobile application (MA) enabled to interact with the SSW, and equipped with GPS tracking. The MA reports GPS coordinates for individual ones of the plurality of players to the SSW periodically, and the SSW identifies clusters of players based on pre-programmed geography limitations, and uses cluster data for various interactions between players and the system, and between players and other players.
US11020671B2	System and method for enhancing participation in online multiplayer sessions Session participation in online content streams or activities like multiplayer games is enhanced through management of session tracking and automated queuing of players via a central system between host/streamer client device and guest player client devices. Spectators viewing a content stream or waiting to join a multiplayer activity over a network via a game/streaming service request to be placed in a queue to participate in a session of the content stream or activity as guest players with the host/streaming user. Sessions are tracked to determine start and end events. Sets of prior guest players are removed from sessions when the sessions end, and sets of queued spectators are automatically added to the start of a new session of the content stream or activity as guest players. Queuing may be automatically prioritized for users based on user characteristics, and guest players removed at the end of sessions may be automatically re-queued.
US11020667B2	Apparatus for adapting virtual gaming with real world information A server device that incorporates teachings of the present disclosure may include, for example, a memory and a processor. The processor can identify first and second players present at first and second physical locations, to identify first and second boundary and topographical information of the first and second physical locations, to map the first and second boundary and topographical information of the first and second physical locations to a virtual gaming space, to capture first and second position and orientation information for the first and second players, to map the first and second position and orientation information to the virtual gaming space, to generate first and second virtual players corresponding to the first and second players, and to transmit to first goggles information representative of the second virtual player for display superimposed onto a transparent viewing apparatus for viewing of the virtual gaming space. Additional embodiments are disclosed.
US11020666B2	Systems and methods for prioritizing content packets based on a dynamically updated list of content filtering rules Systems and methods for prioritizing content packets based on a dynamically updated list of content filtering rules are described. A system is configured to identify an application executing on a client device to which to transmit content, the application associated with an account and determine that the application is configured with a configuration setting to apply a content filtering policy corresponding to a list of players including one or more players included in one or more lineups associated with the account. The system can receive a content item from a content source and determine one or more player tags associated with the content item. The system can determine that the content item includes a player tag corresponding to a player included in the list of players and transmit the content item to the client device for insertion in a content feed provided by the application responsive to the determination.
US11020657B1	Systems and methods for identification and automation of gaming competition reporting and integrity A system comprises a database stored on a server and a processing device of the server. The processing device is in communication with a user device accessible to a user. The processing device includes a hosting unit, a communications unit, an image processing unit, and a validation unit. The hosting unit is configured to generate and display a web-based application on a user device. The communications unit is configured to enable the user to access and interact with the web-based application on the user device and receive at least one user-submitted image and a plurality of user-submitted data from the user. The image processing unit is configured to process the at least one user-submitted image to retrieve game data. The validation unit is configured to compare the plurality of user-submitted data with the game data and validate the game data.
US11020654B2	Systems and methods for interaction with an application A system and method for interaction with a user are provided. The system may include a head-mounted display device, at least one sensor implemented on the head-mounted display device, at least one storage medium including a set of instructions, and at least one processor configured to communicate with the at least one storage medium. When executing the set of instructions, the system may be configured to: acquire, by the at least one sensor, a first facial image of a user; and determine, by the at least one processor, an expression of the user at least based on the first facial image of the user.
US11020653B2	Presenting digital content item with tiered functionality Acquiring an interactive digital content item including a plurality of content portions includes receiving a first set of the content portions that is less than an entirety of the content portions. A partial functionality version of the interactive digital content item is presented using the first set of content portions. A second set of the content portions is received while the partial functionality version of the interactive digital content item is presented. Functionality is added to the partial functionality version of the interactive digital content item using the second set of content portions without interrupting presentation of the partial functionality version of the interactive digital content item.
US11020650B2	Cross-country or ski touring binding The invention relates to a cross-country or ski touring binding for connecting a boot to a ski in an articulated manner, comprising a binding base body with a standing surface for a sole of the boot and a ski contact surface for at least indirect contact with the ski. The binding has a holding device comprising a receiving element which allows the boot to and a holding element for holding the boot on the receiving element. The holding element moves between a closed position holding the boot on the receiving element and an open position releasing the boot. The binding also has an actuating element with a rotating handle for switching the holding element from the closed to the open position, comprising a substantially disk-shaped, eccentrically mounted force-transmission element received in a recess of the holding element.
US11020649B2	Gripping glove A gripping apparatus is disclosed. A gripping glove comprises a wrist band which can be secured with hook and loop fastener patches, and a palm strip with finger loops. The palm strip may be divided into three different strips and allows a comfortable grip during sport activities.
US11020645B2	Ring-shaped punchbag with inner punchball Training equipment is described, and in particular training equipment that can be punched for exercise or for training, e.g., by boxers. The training equipment includes an outer ring-shaped punchbag and an inner punchball positioned within an inner opening of the punchbag. The punchball is connected to the punchbag by a pair of flexible elongate members that can be elasticated cords, for example.
US11020640B2	Multi-component putter An embodiment of a putter type golf club head with an upper and lower portion, made from two different materials, is enclosed herein. Other embodiments are described herein.
US11020637B2	Golf club head having an adjustable weighting system A golf club head includes a club body having a crown opposite a sole, a toe end opposite a heel end, a back end, and a hosel. The golf club head also includes an adjustable weighting system positioned on the club body, the adjustable weighting system includes a single channel and a member that is received by the single channel and fastened to the club body, where a plurality of weights are coupled to the member. The golf club head can additionally or alternatively include a face angle adjustment system positioned on the sole, the face angle adjustment system includes a member that is removably received by the single channel and fastened to the sole, the member includes a first end member and a second end member, wherein the member is configured to be repositioned within the channel to adjust a resting face angle of the golf club head.
US11020635B2	Golf club head customization A method of customizing a golf club, wherein the method includes generating operating data representative of a user operating a mechanical device. The operating data is generated by a first sensor sized and configured to be removably positioned in a mounting port formed on the mechanical device during operation of the mechanical device. The sensor is interchangeably positionable in the mounting port with at least one mass insert, the at least one mass insert being adapted to be interchangeably positioned in the mounting to provide at least two different mass configurations. The method further includes determining a recommended configuration of the at least one mass insert specific to the user based on the operating data generated by the sensor, and transmitting information representative of the recommended mass insert.
US11020631B2	Systems, devices, and methods including a spinal resistance assembly Systems, devices, and methods are described for providing, among other things, a neck and spine strengthening device. The strengthening device includes a spinal resistance assembly configured to apply a resist force or to resist rotation about at least a first axis, and a head affixing assembly configured to secure to a head of a user during use. The strengthening device is instrumented with sensors and an embedded computing system configured to securely exchange exercise performance and configuration data with local client devices, and to monitor and record exercise activity and exercise performance data.
US11020628B2	Display device and control method therefor The present invention relates to a display device including a communicator configured to communicate with an external apparatus that operates for a workout of a user; a display configured to display an image; and a controller configured to determine workout conditions of the user, and control the communicator to transmit a control signal to the external apparatus so that the display can display a corresponding image and the external apparatus can change the operation in accordance with the determined workout conditions of the user.
US11020623B2	Storage fire protection fluid distribution device and deflector A sprinkler includes a sprinkler frame and a deflector. The deflector is disposed about the sprinkler and centered along a sprinkler axis with an internal deflecting surface circumscribed about the sprinkler axis, the internal deflecting surface having a central region, a peripheral region and an arcuate annulus region between the central region and the peripheral region, the central region being a planar surface disposed perpendicular to the sprinkler axis and contiguous with the arcuate annulus to define a first diameter of the deflector, the arcuate annulus being contiguous with the peripheral region to define a second diameter of the deflector and the peripheral region including a plurality of spaced apart planar surfaces skewed outwardly with respect to the sprinkler axis to form an outermost discontinuous peripheral edge of the deflector to define a third diameter of the deflector.
US11020622B2	Fire protection sprinkler assembly A sprinkler assembly (10) having a receiving member (12), a fluid tight seal (44) and a sprinkler frame (14). The receiving member includes an inner surface (22) defining an internal passageway and a central axis (A-A) of the assembly. The frame of the sprinkler includes an internal surface (38) that defines a fluid passage. The sprinkler assembly includes cooperating positioning elements (28, 40) which engage and couple the sprinkler frame to the receiving member for at least one of an axial and rotational adjustment between the frame and receiving member. The engaged positioning elements facilitate formation or location of the fluid tight seal between the sprinkler frame and receiving member, the seal being spaced from the engaged positioning elements. In one aspect of the assembly, the sprinkler frame and receiving member are made of plastic material (e.g. CPVC).
US11020616B2	Determining a distribution of spots of varying sizes for ion beam therapy using optimization According to a first aspect, it is presented a method for determining a treatment plan comprising a distribution of spots for use with ion beam therapy for providing the spots in a target volume. The method comprises the steps of: selecting energy layers to be used in the treatment plan; determining a number of spot sizes to use; generating, for each energy layer, one copy of the energy layer for each spot size to use and populating each copy with spots of the spot size for that copy; optimizing spots of all copies of all energy layers, by repeatedly varying a weight of at least a subset of the spots and calculating an effect on a performance measurement, wherein the performance measurement is calculated by combining a plurality of evaluation criteria, comprising a first criterion related to total treatment time and a second criterion related to a desired dose distribution.
US11020613B2	Physician directed radiation treatment planning The treatment planning engine empowers radiation treatment decision makers, such as a physician, to efficiently identify effective radiation treatment outcomes for a given patient during the contouring stage. Specifically, using the treatment planning engine, the physician may iteratively and in real-time evaluate different treatment outcomes for a patient before selecting an optimal outcome that will guide the delivery of radiation treatment to the patient. By providing real-time information as to potential toxicity and treatment efficacy during the contouring stage, the physician is empowered to make informed decisions at the preliminary contouring stage.
US11020601B2	Accessory for external cardiac defibrillation, pacing and monitoring physiological signals/health data in the presence of electromagnetic interference This accessory adapts external cardiac defibrillation systems to enable safe defibrillation, pacing, and cardioversion inside the MRI bore with minimal effect on MR image quality. Commercially available external defibrillators are not designed to work in the MRI environment. An MR-compatible defibrillator is needed to safely perform cardiovascular MRI, in particular MR-guided interventional cardiovascular procedures, such as cardiac electrophysiology studies and cardiac catheterization. This accessory includes nonmagnetic defibrillator housing with MRI safety features, provides interface for MRI-compatible physiological monitoring, and optimizes defibrillator operation for the MRI environment. The accessory may include MRI-compatible modules for monitoring/recording electrocardiogram, blood pressure, pulse oximetry, and other physiological signals. It may also include a wireless transmitter and at least one module for electrical energy generation and/or stimulation.
US11020594B2	Electrochemical dephosphorylation technique for treating Alzheimer's disease and use thereof The invention relates to an electrochemical dephosphorylation technique for treating Alzheimer's disease and a use thereof. It comprises a gold electrode provided with a negative potential of −0.2 V to −0.6 V on a surface thereof.
US11020589B2	Multi-electrode epicardial pacing Systems and methods for epicardial pacing are provided. For example, this document provides epicardial pacing using a percutaneously delivered bifurcated pacing lead that has multiple electrodes that are directionally insulated to prevent extracardiac stimulation, including prevention of phrenic stimulation. In addition, the devices, systems, and methods provided can be used for ablation, defibrillation, and/or defibrillation in combination with pacing.
US11020583B2	Aortic connectors and methods of use Connectors interfacing a mechanical circulatory system with a patient's natural vasculature are provided herein. Such connectors include aortic connectors that facilitate fluid coupling of an outflow graft tube from an implanted blood pump with a patient's aorta. Aortic connectors can include a substantially planar portion configured for sealed attachment with a wall of the aorta and a tubular connector portion extending from an inlet opening to an outlet opening. The substantially planar portion can include a flexible membrane for attachment to an outer surface of the aorta and/or a flange for engagement with an inner surface of the aorta. The tubular connector can extend from the substantially planar portion at a pre-determined angle and include one or more attachment features to facilitate rapid fluidly sealed attachment to the outflow graft tube.
US11020580B2	Catheter assembly A catheter assembly including a catheter hub being connectable to a device for the infusion or withdrawal of fluids; a hollow extension tube connected at its distal end to the catheter hub, the extension tube connectable at its proximal end to a device for infusing fluid into the chamber within the catheter hub; a valve assembly disposed within the chamber of the catheter hub having a first valve member and a second valve member preventing the flow of fluid through the chamber to or from the proximal end of the catheter hub. A needle guard assembly is also provided.
US11020575B2	In vivo drug delivery devices and methods for drug delivery Drug delivery devices and methods of administering drugs to patients are provided. A device (50) includes a reservoir (60) containing a drug (58). The reservoir (60) is defined by a wall (64) having a water-permeable portion, such that the water-permeable portion permits water to enter the device (50) and contact the drug (58). A restraining plug (56) closes off an opening of the device (50) such that transient microchannels (62) form between an elastic portion (54) of the device (50) and the restraining plug (56), upon the generation of a sufficient pressure within the reservoir (60), to release the drug (58) from the device (50). Methods of treating patients for neurogenic detrusor overactivity resulting from a spinal cord injury and/or for idiopathic overactive bladder and urinary incontinence are also described.
US11020567B2	Medical article securement device comprising a viscoelastic polymer Medical article securement systems comprising a viscoelastic polymer and optionally a base layer for securing a medical article to the body of a patient, and particularly, for securing various catheter systems, tubes, or other elongated medical devices to the body of a patient and methods of making and using such.
US11020562B2	Insertion device for insertion of a medical implant An insertion device for the insertion of a medical implant into a human and/or animal body. The device has at least one outer shaft, which has a proximal end and a distal end opposite the proximal end. A receiving element is connected to the outer shaft, for the implant. The outer shaft and the receiving element are surrounded at a transition between the outer shaft and receiving element by a locally placed sleeve, which dampens mechanical tensile and/or compressive stresses.
US11020561B2	Medical device package with a twist cap A package for a medical device such as an intermittent catheter has a case and a cap connected by threads. The case includes a hollow tube which is closed at one end and open at the other. A shoulder is formed near one end of the case. Above the shoulder is a cylindrical ferrule that includes external threads. The cap has internal threads selectably engageable with the threads on the ferrule to form a liquid-tight seal between the cap and case when the cap is installed on the case.
US11020559B2	Unobtrusive nasal mask A patient interface for delivering breathable gas to a patient includes a sealing portion including a nose tip engagement portion adapted to form a seal with the patient's nose tip, an upper lip engagement portion adapted to form a seal with the patient's upper lip and/or base of the patient's nares, and nostril engagement flaps adapted to form a seal with the patient's nares. The nose tip engagement portion, the upper lip engagement portion, and the nostril engagement flaps are all structured to extend or curve outwardly from a supporting wall defining an air path.
US11020555B2	Tube introducers, assemblies and methods A tracheostomy tube introducer (1) has a patient end region (10) on which the tube (2) is mounted and that is curved in one sense. The introducer has a machine end region (11) projecting from the rear end of the tube (2) to provide a handle that curves in the opposite sense to the patient end region (10) so that the introducer has an S shape along its length. A bore (24) for a guide member extends from the patient end tip (14) of the introducer and opens in the machine end region (11) through a side opening (25). The introducer 1 is provided in a kit (200) with the tracheostomy tube (2) and a dilator (202) having the same general S shape as the introducer.
US11020550B2	Device and system There is disclosed a device for nicotine delivery, comprising: a vapour outlet conduit for coupling to, and for fluid communication with, a vapour creation system, said vapour outlet conduit defining a fluid passage therethrough for delivery of vapour from a vapour creation system to a user; wherein said vapour outlet conduit comprises a nicotine carrier unit region configured to accept a nicotine carrier unit and retain said nicotine carrier unit in said fluid passage. Also disclosed is a system for nicotine delivery and kits-of-parts for assembling the device and system.
US11020545B2	Electrosurgical gas control module A gas control module for a gas-enhanced electrosurgical system. The gas control module has an inlet port, a first solenoid valve connected to said inlet port, a first pressure sensor, a first pressure regulator, a first flow sensor, a first proportional valve, a second flow sensor, a second solenoid valve, said second solenoid valve being a 3-way valve, a vent connected to said second solenoid valve, a second pressure sensor, a third solenoid valve and an exit port.
US11020544B2	Composite heating type flue-curing device and composite heating method for cigarettes A flue-curing device comprises a case, one end of the case is provided with an opening, and a fixing barrel communicated with the opening is defined an inner portion of the case, the fixing barrel is sequentially provided with a heating chamber and an airflow heating pipe; the airflow heating pipe is sleeved by a heat generating assembly configured to heat air that is to flow to the cigarette and to transfer heat to the heating chamber to heat the cigarette; or the airflow heating pipe and the heating chamber are both sleeved by the heat generating assembly configured to simultaneously heat the heating chamber and the airflow heating pipe to achieve a composite heating of the cigarette. The present application can solve the problem that the cigarette evaporation is insufficient or the evaporation is too fast, and satisfy a habit of a user to smoke for a long time.
US11020543B1	Decubitus ulcer healing airflow device A decubitus ulcer healing airflow device includes a motorized airflow intake fan disposed within a housing body devised to be attached to a bed rail A tubular airflow outlet is attached to a rear side of the housing body. An air filter slideably engages an access slot and is disposed between a protective grill and an airflow intake fan. At least one strap has a central elastomeric central section engageable onto the bed rail and a pair of u-shaped outer ends. Each strap engages a respective one of a pair of strap support holders disposed on each or one of a top and bottom side of the housing body. A slotted compartment, within the airflow outlet, contains a fragrance or a vaporized medicine to assist in healing the ulcers.
US11020529B2	Sensor for a drug delivery device In one aspect the present disclosure relates to a sensor for measuring at least one physical or chemical parameter of a cartridge filled with a liquid substance. In a further aspect the disclosure relates to a drug delivery device equipped with such a sensor, wherein the sensor includes a planar flexible foil having a first section and having a second section separated from the first section,at least one measurement electrode located on the flexible foil, wherein the flexible foil is wrappable into a wrapped configuration in which the foil forms at least a first wrap with an inner diameter that is equal to or larger than an outer diameter of the cartridge, wherein in the wrapped configuration the first section and the second section at least partially overlap, at least one fastener located in one of the first and second section and configured to attach to the other one of the first and second sections for keeping the flexible foil in the wrapped configuration.
US11020525B2	Injector cartridge door locking mechanism An injector includes an injector housing and a cartridge door movably mounted to the injector housing between a fully closed position and an open position. A latching mechanism is movable between a latched position, locking the cartridge door to the injector housing in the fully closed position thereof, and an unlatched position, unlocking the cartridge door from the injector housing, thereby enabling movement of the cartridge door toward the open position. The latching mechanism is oriented in the unlatched position when the cartridge door is empty and the latching mechanism is configured to move to the latched position solely when a cartridge is present in the cartridge door and the cartridge door is subsequently moved to the fully closed position thereof.
US11020524B1	Peristaltic micropumps and fluid delivery devices that incorporate them In one embodiment, a peristaltic micropump comprising a substrate having a first side and a second side, a microtube that extends across the first side of the substrate, and multiple pump actuators formed on the first side of the substrate and positioned adjacent to the microtube at discrete, spaced positions along the length of the microtube, wherein the micropump is configured to sequentially actuate the pump actuators so as to create peristaltic action that drives fluid contained in the microtube along the length of the tube.
US11020517B2	Treatment solution delivery in an extracorporeal blood treatment apparatus Blood treatment apparatus and methods of using the same are described herein that include two or more intermediate containers located between a treatment solution source and a port through which the treatment solution is to be delivered with the blood treatment apparatus. The weight of the intermediate containers is measured and used to control the refilling and emptying of treatment solution in the intermediate containers.
US11020511B2	Device and production method for the same A device includes a substrate and a hydrophilic polymer layer made of a hydrophilic polymer having a hydroxyl group. The hydrophilic polymer layer having a hydroxyl group is fixed to at least a part of a surface of the substrate and the hydrophilic polymer further has an amide group. A liquid film retention time of the device is 15 seconds or more. The device has a surface of a substrate which is hydrophilized. A method for producing the device by a simple method is also disclosed.
US11020507B2	Hemorrhage management system An embodiment includes a wound dressing comprising: a shape memory polymer (SMP) foam, including open cells, having first and second states; and a hydrogel (HG) included within the cells; wherein (a) in a first position a composite, including the SMP foam and the HG, is configured to be located proximate a hemorrhagic tissue with the SMP foam in the first state; (b) in a second position the composite is configured to be expanded to the second state against the hemorrhagic tissue when the SMP foam is plasticized at 37° C. depressing a glass transition temperature (Tg) of the SMP foam to below 25° C. Other embodiments are described herein.
US11020506B2	Decontamination apparatus and method Provided is a decontamination apparatus that includes a motorized base with a transport system that is operable to autonomously move the decontamination apparatus. A plurality of UVC bulbs, each of which emits UVC light, are supported at a vertical elevation above the motorized base. A controller controls operation of the transport system to move the decontamination apparatus along a desired route while the UVC bulbs are energized during a decontamination process.
US11020505B2	Apparatus and method for detecting moisture in a vacuum chamber A method of sterilizing medical instruments using a vacuum chamber connected to reservoir by a valve in a closed state is disclosed that includes placing instruments in a non-sterile state into a sterilization pack, opening a chamber, placing the pack into the chamber, closing the chamber, withdrawing a first volume of air from the chamber, changing a volume of liquid water into vapor, opening the valve, introducing sterilant into the chamber, introducing a second volume of air into the chamber, opening the chamber, removing the pack from the chamber, and removing the instruments in a sterile-state from the pack. The process may further include the steps of repeatedly determining pressure within the chamber, calculating second-derivative values of pressure with respect to time, and determining whether any local maxima exist in a plot of second derivative values that correspond to pressures above and/or below the triple-point pressure of water.
US11020504B2	Environmental sanitizing device and method therefor Environmental sanitizing device including a frame housing a disinfectant liquid reservoir and supporting a nozzle, the nozzle associated with a generation system of an air flow within which a plurality of disinfectant liquid particles are suspended to sanitize a closed environment in which the device can be positioned; the nozzle is movable with respect to the frame, and associated with positioning system controlled by a control unit for orientation of the nozzle with respect to at least two mutually perpendicular axes, preferably around a first vertical axis and around a second horizontal axis to automatically orient the nozzle in desired direction with respect to the frame during a sanitization step, the nozzle coupled with at least one distance detector able to determine distance between the nozzle and an obstacle facing the nozzle.
US11020501B1	Handheld ultraviolet irradiation device having distance measurement system A handheld light assembly for eradicating pathogens includes a housing. A processor and a lamp are disposed inside the housing. The lamp irradiates surfaces with disinfecting ultraviolet light having a peak wavelength of 222 nm filtered to restrict illumination to between 200 nm and 230 nm within an irradiation zone. A distance measuring system includes a secondary light source generating secondary light and a photodetector for measuring distance of the secondary light to a surface being irradiated by the lamp light being reflected from the surface to the photodetector. The secondary light source is offset at an angle from the lamp thereby projecting the light beam to a central area of the irradiation zone generated by the lamp. The photodetector signals the processor to calculate a vertical distance between the lamp and the central area of the irradiation zone on the surface being irradiated from an angular projection of the secondary light.
US11020498B2	Portable and disposable far-UVC device A method of destroying pathogens disposed upon an epidermis includes providing a hand held device including a grip and a lamp, transmitting far-UVC light via the lamp, and filtering the transmitted far-UVC light to attenuate portions of transmitted UVC light that have a wavelength known to cause damage to an epidermis of a human. The epidermis is scanned by tracing the hand held device over a localized area of the epidermis thereby illuminating the localized area with the filtered far-UVC light. The filtered far-UVC light destroys pathogens disposed upon the epidermis while not causing adverse biological damage to the epidermis.
US11020497B2	Rod-shaped plant virus nanoparticles as imaging agent platforms A rod-shaped plant virus having an interior surface and an exterior surface, and at least one imaging agent that is linked to the interior and/or exterior surface is described. The rod-shaped viruses can be combined into larger spherical nanoparticles. A rod-shaped plant virus or spherical nanoparticles including an imaging agent can be used in a method of generating an image of a tissue region of a subject such as a tumor or atherosclerotic tissue by administering the virus particle to the subject and generating an image of the tissue region of the subject to which the virus particle has been distributed.
US11020496B2	Compositions for neuromodulation of mosquito feeding behavior and uses thereof The present disclosure relates to compositions and methods for enhancing mosquito feeding.
US11020487B2	Compositions for introducing nucelic acid into cells The present invention relates to polymers comprising a characteristic combination of alkylene amine moieties which are useful as vehicles for transfecting a cell with a nucleic acid. The present invention furthermore relates to a composition comprising a nucleic acid and such a polymer, and to a method of transfecting a cell using said composition. Furthermore, the present invention relates to pharmaceutical compositions and uses.
US11020486B2	Sesame oil based injection formulations Injectable formulations comprising ethanol, sesame oil, and an Immune Response Modifier compound are disclosed. Methods of making the formulations and methods of using the formulations for treatment of a disease in a subject, e.g., neoplastic disease, comprising injecting the formulations into a subject hi need of treatment, are also provided.
US11020485B2	Pharmaceutical formulation Disclosed are aqueous pharmaceutical compositions which provide sustained released delivery of corticosteroid compounds. The pharmaceutical composition comprises a soluble corticosteroid and at least one viscosity enhancing agent. Also provided are methods for using the pharmaceutical compositions in an epidural injection, intra-articular injection, or an intra-lesional injection.
US11020483B2	Pharmaceutical compositions comprising meloxicam Disclosed herein are compositions comprising an NSAID such as meloxicam and/or rizatriptan in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These compositions may be orally administered, for example, to improve the bioavailability or pharmacokinetics of the NSAID for the treatment of pain such as migraine, arthritis, and other conditions. Also disclosed herein are methods of treating pain, such as migraine, comprising administering meloxicam and rizatriptan to a human being suffering from pain, such as migraine. For migraine, these methods may be particularly useful when the meloxicam and rizatriptan are administered while the human being is suffering from an acute attack of migraine pain or migraine aura. In some embodiments, the combination of meloxicam and rizatriptan may be administered in a manner that results in a Tmax of meloxicam of 3 hours or less.
US11020482B2	Methods and compositions related to inhibition of viral entry Disclosed herein are compositions and methods for inhibiting viral entry.
US11020479B2	Method for production of solid water particles for homeopathy A method for production of solid water particles for homeopathy uses principles of quantum physics to from a concentrated solid water particle solution. A homeopathic ingredient solution is diluted in purified water in an inert gas environment. The dilution occurs as infinitesimal doses, in which the solution is repetitively diluted in water past the point where few molecules from the solution remain. An electrical field is applied to align the water molecules for formation of a large clump of solid water particles. Alternating phases of ultrasonic vibrations break down the large clump into small clusters of solid water particles. The vibration is followed by periods of rest, whereby the small clusters grow into successively larger clumps by absorbing water molecules. The vibrations and resting are repeated in cycles until a desired concentration of solid water particles form in the solid water particle solution.
US11020478B2	Methods for modulating angiogenesis of cancers refractory to anti-VEGF treatment A method for modulating angiogenesis in a cancer or tumor refractory to anti-VEGF, including identifying a cancer cell as being referactory to anti-VEGF, and then contacting the cancer cell refractory to anti-VEGF with an effective amount of an agent that modulates interaction between Gal1 or a Gal1 fragment and the natural binding partner of Gal1 or the Gal1 fragment to thereby modulate angiogenesis.
US11020476B2	Methods and compositions for inducing an immune response against Hepatitis B Virus (HBV) Provided herein are Modified Vaccinia Ankara (MVA) vectors and adenovirus vectors encoding HBV antigens. Also provided are methods of enhancing an immune response in a human subject by utilizing the MVA and adenovirus vectors encoding HBV antigens in a prime/boost regimen to the enhance the immune response in the human subject.
US11020474B1	Producing recombinant SARS-CoV-2 spike protein in a pre-fusion state Disclosed is producing recombinant SARS-CoV-2 spike protein in a pre-fusion state, using furin knock out or knockdown mammalian cells (such as HEK293, CHO or other mammalian cells). The pre-fusion state SARS-CoV-2 spike protein can be used as an antigen to generate antibodies/binding molecules for use in SARS-CoV-2 detection assays or in diagnosis of active or prior infection with SARS-CoV-2; as a therapeutic to interfere with SARS-CoV-2 cellular binding; to generate antibodies/binding molecules to SARS-CoV-2 for use in therapy; or, as a vaccine for generating immunity to SARS-CoV-2; or for prophylactic or therapeutic use against related coronaviruses.
US11020463B2	Method of determining cellular protein homeostasis The present invention provides assays and compositions to identify the risk of toxicity in a patient population with genotypic variations in specific proteins and/or protein complexes within the patient population.
US11020455B2	Colony stimulating factor for use in pancreatic or colon cancer treatment There is provided a Colony Stimulating Factor (CSF) as an active ingredient for use in the treatment of colon or pancreatic cancer through an increase in neutrophilia, wherein the Colony Stimulating Factor is selected from the group consisting of Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) and Granulocyte Colony Stimulating Factor (G-CSF). The new use for these two recombinant proteins represents a new treatment option for two of the most frequent forms of cancer.
US11020452B2	Stem cell stimulating compositions and methods of treating melasma Compositions and methods for topical treatment of the hyperpigmented lesions of melasma are presented. Such compositions include defensins in concentrations that are below those that exhibit antimicrobial activity, and can be in the form of a topically applied gel, lotion, wash, shampoo, cream, or mask. Various formulations for such compositions, which can include various pharmaceutically acceptable stabilizers, emollients, and fragrances, are provided.
US11020450B2	Medical use of CREG protein The present invention relates to a medical use of Cellular Repressor of E1A-stimulated Genes (CREG), in particular to a use of CREG protein or active fragment thereof in manufacture of a medicament for preventing and/or treating myocardial infarction, a use in manufacture of a medicament for preventing and/or treating ventricular remodeling after myocardial infarction and heart failure after myocardial infarction, a use in manufacture of a medicament for prevention and/or treatment of myocardial ischemia-reperfusion injury, a use in manufacture of a medicament for prevention and/or treatment of salt-sensitive hypertensive myocardial fibrosis.
US11020442B2	Vibrio parahaemolyticus bacteriophage Vib-PAP-2 and use thereof for inhibiting proliferation of Vibrio parahaemolyticus The present invention relates to: Podoviridae bacteriophage Vib-PAP-2 (accession number KCTC 12910BP) which has the capability to specifically destroy Vibrio parahaemolyticus, is characterized by having a genome represented by SEQ ID NO: 1, and is isolated from nature; and a method for preventing and treating Vibrio parahaemolyticus infections, using a composition containing bacteriophage Vib-PAP-2 as an active ingredient.
US11020438B2	Phospholipid compositions and their preparation The invention provides improved processes for extracting and preparing polar lipids (in particular, desirable phospholipids) from krill and other biological sources. The inventors have discovered processes through which it is possible to extract phospholipids to give high phospholipid content and a reduction of undesired components.
US11020437B2	Methods for treating nuclear factor kappa-light-chain-enhancer of activated B cell (NF-KB) dysregulation in a host in need thereof using eggshell membrane compositions The present invention relates to the use of eggshell membrane compositions to activate levels of nuclear factor kappa-light-chain-enhancer of activated B cells (“NF-κB”) in the gut of a host in need thereof and methods of treating conditions related to NF-κB dysregulation.
US11020433B2	Peptides and combination of peptides of non-canonical origin for use in immunotherapy against different types of cancers The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11020431B2	Compositions and libraries comprising recombinant T-cell receptors and methods of using recombinant T-cell receptors Provided are recombinant polynucleotides, including expression vectors encoding an alpha chain and/or a beta chain of a TCR having amino acid sequences from any of novel the AL, KQ, PP, 19305CD8, BB, KB, ST, JD, 19305DP, PB-P, PB-T, and PB 13.2 T Cell Receptors (TCRs) that are embodiments of the invention. Cells comprising the polynucleotides are provided, as are libraries of the recombinant polynucleotides and expression vectors. Methods are provided and involve administering to an individual modified human T cells that express a novel recombinant TCR. The methods are for prophylaxis and/or therapy of an individual diagnosed with, suspected of having or at risk for developing or recurrence of a cancer, wherein the cancer includes cancer cells which express NY-ESO-1 and/or its highly homologous LAGE-1 antigen.
US11020429B2	Vectors and genetically engineered immune cells expressing metabolic pathway modulators and uses in adoptive cell therapy Provided are cells, e.g., engineered immune cells, expressing recombinant or engineered molecules involved in metabolic pathways, such as those that promote or inhibit one or more metabolic steps, reactions, or pathways, for example, in T cells. Such molecules include those that induce or repress a particular functional outcome or metabolic event, for example, one that promotes differentiation or reprogramming into a particular phenotypic state, such as memory, long-lived, activated or activatable, non-exhausted, phenotype or stem-like phenotype. The cells generally further express an immune receptor, such as an antigen receptor, which may be an engineered receptor, such as a CAR or recombinant TCR, or may be a natural immune receptor. Also provided are cells, such as T cells, expressing such molecules and combinations thereof, compositions comprising such cells, nucleic acids such as vectors encoding the same, and methods of administration to subjects in adoptive cell therapy.
US11020424B2	Modified immune-modulating particles The presently claimed invention relates to methods of reducing the duration or severity of an inflammatory immune response. In embodiments, the method comprises administering poly (lactic acid) (PLA) particles, poly (glycolic acid) (PGA) particles, poly (lactic-co-glycolic acid) (PLGA) particles, or combinations thereof; wherein said particles are modified to contain one or more carboxyl groups on the particle's surface. In embodiments, the particles do not comprise therapeutically active ingredients.
US11020421B2	Superabsorbent materials and methods of production thereof The present invention relates to new methods for crosslinking a polysaccharide with a bifunctional poly(ethylene glycol). The invention further includes the polymer hydrogels which can be produced using these methods, compositions comprising the polymer hydrogels and methods of use thereof.
US11020409B2	Broad antiviral therapy with membrane modifying oxysterols This invention relates, e.g., to a method for inhibiting the growth and/or proliferation and/or infectivity of a virus in a cell, such as a mammalian cell (e.g. for inhibiting entry of the virus into the cell), comprising administering, or causing to be administered, to the cell, 25-hydroxycholesterol (25HC) in an amount sufficient to inhibit the growth and/or proliferation and/or infectivity of the vines in the cell. The method can be carried out in vivo or in vitro. Among the viruses that can be inhibited are, e.g., VSV, HSV, MHV68, HCV, HIV, EBOV, RVFV, RSSEV and Nipah virus. In one embodiment of the invention, the 25HC is administered topically, e.g. to a mucosal surface.
US11020408B2	Polymer composed of repeat units having a biologically active molecule attached thereto via a pH-sensitive bond There is provided a polymer comprising: (i) a repeat unit derived from a compound of formula (I) (Formula (I)) wherein, R1 and R2 are each independently selected from OH, OR′, SH, SR′, NH2, NHR′ and NR′2; R′ is C1-20 hydrocarbyl; each n is independently 0 or an integer between 1 and 6; each m is independently 0 or an integer between 1 and 4, and preferably at least one m is 1; and q is an integer between 1 and 8; and; (ii) a biologically active molecule, wherein said biologically active molecule is covalently bonded to said repeat unit; as well as methods for preparing such polymers, particles comprising said polymers and uses of said polymers and particles including use in the treatment of disease.
US11020406B2	Compositions comprising omega-3 fatty acids, 17-HDHA and 18-HEPE and methods of using same The present invention relates to a polyunsaturated fatty acid composition comprising Omega-3 fatty acids, 17-HDHA and 18-HEPE. The composition can furthermore comprise DPA and/or an acceptable carrier and can be present in a capsule or other suitable dosage unit. The invention also relates to the process of obtaining the composition and methods for using same.
US11020403B2	Precipitation resistant small molecule drug formulations Embodiments of the invention are directed to formulations that provide a solution to the problem of small molecule (e.g., diazepam) precipitation at the injection site when administered as a highly-concentrated formulation. In certain aspects the formulations include at least one surfactant in a non-aqueous formulation, which prevents small molecule precipitation and improves the bioavailability of the drug by enhancing absorption into the systemic circulation.
US11020391B2	CRMP2 sumoylation inhibitors and uses thereof The present invention provides compounds that can modulate the amount of Nav1.7 protein, a key protein in pain signaling, that is present in the cellular surface and methods for using such compounds. In particular, compounds of the invention modulate the amount of Nav1.7 protein on the cellular surface by modulating SUMOylation of CRMP2. Thus, compounds of the invention can be used to treat various clinical conditions associated with the presence and/or activation of Nav1.7 protein on the cellular surface and/or SUMOylation of CRMP2.
US11020385B2	Combination therapy Described herein are compounds and compositions for treating glaucoma and/or reducing intraocular pressure. Compositions may comprise an isoquinoline compound and a prostaglandin or a prostaglandin analog. Compounds described herein include those in which an isoquinoline compound is covalently linked to a prostaglandin or a prostaglandin analog, and those in which an isoquinoline compound and a prostaglandin free acid together form a salt.
US11020384B2	Antiarrhythmic formulation Pharmaceutical compositions comprising an antiarrhythmic agent for treatment of a heart condition via inhalation. Methods of treating a heart condition include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. Nebulized drug product and kits are also disclosed.
US11020383B2	Methods for the treatment of cancer metastasis Provided herein are methods of preventing or treating cancer metastasis by administering an allosteric ligand of proteasomes. Further provided are methods of monitoring the efficacy of treatment with an allosteric ligand for reducing metastatic potential of a tumor.
US11020381B2	Biaryloxy derivatives as TTX-S blockers The present invention relates to biaryloxy derivatives which have blocking activities of voltage gated sodium channels as the TTX-S channels, and which are useful in the treatment or prevention of disorders and diseases in which voltage gated sodium channel is involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which voltage gated sodium channels are involved.
US11020379B2	3-(phenyl)-N-(4-phenoxybenzyl)-1,2,4-oxadiazole-5-carboxamide compounds for the management of CFTR protein mediated diseases This disclosure relates to methods of treating or preventing cystic fibrosis transmembrane conductance regulator (CFTR) mediated diseases such as cystic fibrosis, chronic obstructive pulmonary disease, chronic pancreatitis, chronic bronchitis, asthma, mucus formation, comprising administering an effective amount of a 3-(phenyl)-N-(4-phenoxybenzyl)-1,2,4-oxadiazole-5-carboxamide compound, salt, or derivative thereof to a subject in need thereof. In certain embodiments, the 2-amino-N′-benzylidene-acetohydrazide compound is 3-(3,5-dibromo-4-hydroxyphenyl)-N-(4-phenoxybenzyl)-1,2,4-oxadiazole-5-carboxamide.
US11020378B2	Compounds, compositions and methods for treating insulin resistance The invention relates to a compound inhibiting the interaction between a Grb14 protein and an insulin receptor of Formula (I) or Formula (II), their salts, solvates, and/or diastereoisomers, for use for therapeutic purposes, in particular for the treatment of insulin resistance, and to pharmaceutical compositions containing such compounds.
US11020377B2	Secnidazole for use in the treatment of bacterial vaginosis Embodiments are directed to a secnidazole formulations and the use of a secnidazole formulation for the treatment of bacterial vaginosis (BV).
US11020376B2	Crystalline form of lorlatinib free base This invention relates to acrystalline form of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-5-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h] [2,5,11]benzoxadiazacyclo-tetradecine-3-carbonitrile (lorlatinib) free base (Form 7). This invention also relates to pharmaceutical compositions comprising Form 7, and to methods of using Form 7 and such compositions in the treatment of abnormal cell growth, such as cancer, in a mammal.
US11020375B2	Edaravone dosage form Disclosed is an Edaravone dosage form and a use thereof in preparing a drug used for treating diseases related to oxidative stress, the dosage form being selected from a lipid-based delivery system, a solid dispersion, micelles and a co-solvent based formulation.
US11020372B2	Dietary and natural product management of negative side effects of cancer treatment The invention relates to novel methods and compositions for safely reducing negative side effects of cancer treatments. These methods and compositions comprise administering to a patient a composition comprising one or more of the following: curcumin (derived from turmeric), epigallocatechin-3-gallate (EGCG, enriched in green tea), glucosinolates (enriched in cruciferous vegetables) and/or derivatives thereof, such as sulforaphane (SFN), alone or combined with a ketogenic diet or a modified ketogenic diet. Also the current invention relates to a composition comprising medium chain triglycerides (MCT), Epigallocatechin-3-gallate, curcumin, compositions comprising glucosinolates and/or derivatives thereof, such as sulforaphane (SFN). The invention provides that administering a composition comprising curcumin, EGCG, sulforaphane, alone or combined with a ketogenic diet or a modified ketogenic diet (low carbohydrate diet) alone or supplemented with MCT improves resistance of normal cells to cytotoxicity of cancer treatments, in turn, reducing their negative side effects. Increasing normal cells, tissues or organs' resistance to chemotherapeutic agents, the invention improves patients' tolerance to anti-cancer treatments' toxicity, which, in turn, contributes to enhance their efficacy, leading to increased survival of the subject treated with the current invention.
US11020369B2	Treating iron deficiency with ferric carboxymaltose The present invention relates to the field of treating iron deficiency with IV iron carbohydrate complexes such ferric carboxymaltose, monitoring or identifying subjects to determine their eligibility for being administered said IV iron carbohydrate complexes, and combining said IV iron carbohydrate complexes with additional drugs in order to mitigate or reduce side effects induced by said IV iron carbohydrate complexes.
US11020360B2	Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid The invention relates to methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid (3APS) in a subject, preferably a human subject. The invention encompasses compound that will yield or generate 3APS, either in vitro or in vivo. Preferred compounds include amino acid prodrugs of 3APS for use, including but not limited to the prevention and treatment of Alzheimer's disease.
US11020359B2	Method, compositions and device for nano-enhanced opto-chemical trans-differentiation of cells and tissues The present invention relates to novel nanomaterial-molecular compositions, methods and devices thereof for efficient and targeted trans-differentiation of cells including fibroblasts and glia into neurons, both in vitro as well as in situ and in-vivo, which is of great importance for cell replacement therapies. Specifically, the invention provides a nanomaterial-molecular composition, device and method for targeted nano-enhanced opto-chemical trans-differentiation of fibroblasts/glia to neurons in the central and peripheral nervous system for restoration of neural functions in patients by delivery of nanomaterial-molecular composition, followed by optical illumination.
US11020358B2	Method for the anti-senescence of and/or rejuvenating stem cells A method for the anti-senescence of and/or rejuvenating a stem cell is provided. The method comprising treating the stem cell with trans-cinnamaldehyde (TC). A kit is also provided. The kit comprising (1) a first part, comprising a stem cell; (2) a second part, comprising TC; and (3) a culture medium of the stem cell, placed in at least one of the first part, the second part, and a third part. In addition, a method for stem cell therapy is provided. The method comprising administering to a subject in need an effective amount of a stem cell, wherein the stem cell has been treated with TC before being administered.
US11020355B2	Method of encapsulating cannabinoids in phospholipid carriers A method of encapsulating cannabis-derived compounds in nanosized phospholipid vesicles is disclosed. A Cannabis sativa-derived formulation for transmucosal and transdermal delivery comprising Cannabis sativa-derived compounds nanoencapsulated in phospholipid-based vesicles is also disclosed. Cannabis sativa-derived extracts have enhanced bioavailability when encapsulated in nanosized phospholipid vesicles prior to administration to a subject as compared to non-encapsulated cannabinoids. Also disclosed herein are methods of transmucosal and transdermal administration of the formulation having phospholipid vesicles with nanoencapsulated Cannabis sativa-derived substances.
US11020353B2	Film coating composition, solid oral formulation, and method for producing the same Provided are a film coating composition containing a PVA having a degree of hydrolysis of 85.0 to 89.0 mol %, characterized in that even when the composition is used for coating of tablets without any additives other than PVAs, the tablets do not tend to stick to each other; a solid oral formulation using the composition; and a method for producing the same.
US11020352B2	Systems and methods for the fabrication of tablets, including pharmaceutical tablets Systems and methods for fabricating ingestible pharmaceutical tablets are provided. Certain of the systems and methods described herein are capable of manufacturing tablets of different dosages without the need to fluidically connect or disconnect unit operations when switching from a tablet having a first dosage to a tablet having a second, different dosage. Certain of the systems and methods described herein are capable of manufacturing compositionally tablets, e.g., tablets with different active pharmaceutical ingredients (APIs).
US11020350B2	Palatable oral veterinary compositions The present invention concerns palatable veterinary compositions made from one or more pharmaceutical active ingredients having a smell and/or a taste that is repulsive to animals, and a preparation method for preparing said oral veterinary compositions.
US11020349B1	Transmucosal dosage forms of remdesivir Disclosed herein are the sublingual pharmaceutical compositions comprising remdesivir or its pharmaceutically acceptable salts or solvates thereof. The present invention also relates to a process for preparing sublingual pharmaceutical compositions comprising remdesivir or its pharmaceutically acceptable salts or solvates thereof. Compositions of remdesivir prepared as per present invention are able to increase bioavailability by avoiding first-pass metabolism. The compositions of remdesivir prepared as per present invention are useful in the treatment of viral infections including coronavirus infection (COVID-19). The compositions of remdesivir prepared as per present invention exhibit desired pharmaceutical technical attributes such as pH, assay, related substance, disintegration and dissolution.
US11020347B2	No-rinse chemical foam containing trifarotene, and use thereof in the treatment of acne A self-foaming composition is described that includes trifarotene, for a no-rinse topical application and for application to the skin. The composition can include: at least one intermediate composition B including a gas-generating agent; at least one intermediate composition A including an agent for activating the gas-generating agent; and trifarotene or one of the pharmaceutically acceptable salts thereof being present in at least one of the intermediate compositions A and B. The composition is particularly intended for the treatment of acne. Also described is a kit or a single container including a plurality of compartments including such a composition.
US11020346B2	Rhinal spray nozzle used for medical syringe The present invention has a purpose to achieve desired spray characteristics when a pharmaceutical formulation is sprayed by means of a rhinal spray nozzle used for a metered-dose syringe-based squirt.The present invention relates to a rhinal spray nozzle used for a medical syringe having a tip opening in fluid communication with a syringe barrel for storing a pharmaceutical formulation. The rhinal spray nozzle comprises a hollow nozzle body having a tip portion defining a nozzle orifice thereon, a solid packing rod arranged within the nozzle body, and a nozzle chamber defined between the packing rod and the nozzle body to allow a fluid communication between the tip opening and the nozzle orifice, wherein the formulation comprises the gel material containing viscosity modification agent and carboxy vinyl polymer of which viscosity is modified by applying an exogenous shear force, and wherein the nozzle orifice has a diameter in a range between 0.25 mm and 0.30 mm.
US11020344B2	Auricular cleaning composition An auricular cleaning composition includes isopropylic alcohol and/or diethylene glycol monoethyl ether as ceruminolytic agent(s), optionally in combination with caprylocaproyl polyoxyl-8 glyceride.
US11020343B2	Intranasal pharmaceutical dosage forms comprising naloxone The present invention relates to an intranasal pharmaceutical dosage form comprising a dosing unit comprising naloxone or a pharmaceutically acceptable salt thereof in an amount of equivalent to ≥0.5 mg naloxone HC dissolved in an application fluid of a volume of ≤250 μl. Furthermore, the present invention relates to such an intranasal pharmaceutical dosage form for use in the treatment of opioid overdosing and/or at least one symptom thereof.
US11020341B2	Oral care composition comprising cuttlefish bone powder and uses thereof The present document describes an oral care composition comprising a cuttlefish bone powder, comprising particles having more than 95% (w/w) calcium carbonate content, and a particle size of from about 60 microns to about 75 microns, and a suitable carrier, and uses of said composition for oral hygiene.
US11020335B2	Cosmetic coloring material and use thereof The present invention relates to a novel coloring material including a polyamide powder and/or a polyurethane powder and a water-soluble dye. The coloring material of the present invention allows a water-soluble dye to be used in anhydrous formulations. Thereby, the range of use of dyes may be widened, reflectance may be excellent, and fluorescence properties may be obtained. Accordingly, the present invention may broaden the spectrum of cosmetic coloring materials used in limited applications in the cosmetic field.
US11020334B2	Compounds, compositions and use thereof This application relates to compounds prepared from cosmetically acceptable ingredients, methods of preparation thereof, and use thereof. Compounds are of formula (I) U—C—B, or salts thereof, wherein U, C and B are moieties of cosmetically acceptable ingredients U′, C′ and B′. In living tissues, the compounds can release at least one of U′, C′ and B′. The bond between C and U and/or between C and B is labile in living tissues. In particular, the compounds comprise moieties derived from salicylic acid, retinol and retinoic acid or nicotinic acid.
US11020333B2	Organic compounds The present invention refers to indanone derivatives of formula (I) wherein R1 is selected from hydrogen, methyl and ethyl; R2 is selected from hydrogen, methyl and ethyl, and R is selected from hydrogen and methyl; or R2 and R3 form together with the carbon atoms to which they are attached C3-C5 cycloalkyl; and R4 is selected from C2-C5 alkyl, C2-C5 alkenyl, C1-C4 alkoxy, C3-C5 cycloalkyl, and C3-C6 cycloalkenyl. The invention further refers to perfume compositions and fragrance applications comprising them.
US11020332B2	Achillea essential oil, cosmetic composition comprising it and its uses The present invention relates to an Achillea essential oil comprising at least the following compounds, each preferably present in a proportion of at least 5% by weight, with respect to the total weight of the essential oil: artemisia ketone and chrysanthenone (two combined isomers). The invention also relates to a cosmetic composition comprising the said Achillea essential oil and to its cosmetic use as antidandruff agent or as deodorant active agent.
US11020321B2	Occlusion detection for flow control apparatus A method of operating an enteral feeding pump to deliver fluid through a pump set, the method comprising determining with a controller of the enteral feeding pump if an occlusion exists in the pump set based on the controller monitoring a sensor signal from a sensor indicative of a rotational position of a rotor of the pump during operation of a motor of the pump to rotate the rotor at a reduced output less than a feeding output for rotating the rotor to produce fluid flow in the pump set during a feeding cycle, the motor operating at the reduced output for a shorter period of time than the feeding output.
US11020320B1	Pill dispenser for refrigerator appliance A pill dispenser includes a housing and a slidable drawer with a dispenser cup therein. A storage cup is fixed within the housing. The pill dispenser also includes a movable probe, a flexible tip on the probe, and a suction pump in fluid communication with the flexible tip. The pill dispenser may be configured for and/or methods of operating the pill dispenser may include rotating the probe a position above the storage cup, translating the probe downward into the storage cup, and activating the suction pump. While the suction pump is active, the probe is translated to the position above the storage cup, rotated to a position above the dispenser cup, and translated downward into the dispenser cup. The suction pump is deactivated when the flexible tip is within the dispenser cup.
US11020318B2	Push release closed system drug transfer apparatus A push release closed system drug transfer apparatus for easy and secure drug transfer includes a cylindrical housing having a cylindrical housing having a top end, an outer wall, and a bottom end forming an inner cavity. The top end has a syringe aperture to receive a syringe. A needle tube is coupled to the cylindrical housing and extends from the syringe aperture to a principal aperture to receive a needle of the syringe. An inner cylinder is configured to selectively engage connector of a vial. An ejector spring moves the inner cylinder from a compressed position to an alternate decompressed position. A lock mechanism and a release secure the inner cylinder in the compressed position and alternatively free the inner cylinder to move to the alternate decompressed position.
US11020316B2	Dispensing device, valve, containing apparatus having same, contents moving apparatus and contents apparatus The present invention relates to a dispensing device, a valve, a containing apparatus having same, a contents moving apparatus, and a contents apparatus, comprising a passing operation unit provided in the housing, for moving and guiding contents, wherein the passing operation unit comprises a contents passing means for moving the contents. Unlike conventional art, the present invention may secure a space for passing contents while preventing reception of contents, which exceeds a demand, by adjusting a passing space and a receiving space, stably induce passing of a demanded amount of contents within a predetermined range, and prevent remaining of contents more than necessary by limiting the space for receiving the contents, thereby enabling adjustment of the amount (number) of contents being received.
US11020314B2	Methods and systems to reduce brain damage A method to reduce brain injury and brain swelling includes performing active compression decompression cardiopulmonary resuscitation on an individual in a supine position. The individual's head, shoulders, and heart are elevated relative to the individual's lower body. The head is elevated to a height of between about 20 cm and 30 cm above the horizontal plane and the heart is elevated to a height of between about 3 cm and 10 cm above the horizontal plane. Chest compressions are performed on the individual and actively decompressing the individual's chest while the individual's head, shoulders, and heart are elevated. Intrathoracic pressure of the individual is regulated using an intrathoracic pressure regulation device both while the individual is in the supine position and while the individual's head, shoulders, and heart are elevated relative to the lower body, thereby reducing brain edema during CPR.
US11020311B2	Therapeutic device and method for stimulating the anatomy of the cervical spine and neck A therapeutic device for stimulating the anatomy of the cervical spine and neck is provided and includes a housing having an upper portion configured for receiving and cradling the cervical spine and the neck. The therapeutic device includes a motorized rotor assembly having a plurality of rollers. The rotor assembly rotating about a first axis and the plurality of rollers rotating independently from one another and about axes spaced from the first axis. The rotor assembly is configured to transmit percussive energy to the cervical spine and the neck.
US11020308B2	Ambulatory aid An ambulatory aid, such as a crutch, including a pair of support members connected by a load bearing handle member, and terminating at a first end with a top axilla-conforming member, and a second end with a foot piece. The crutch is used as a straight arm crutch, in which a user's weight is distributed in the hand to keep the arm straight, while preventing any load on the shoulder girdles. The crutches are configured to fit close to the body, to centralize the base of support, and keep the center of gravity lower, thereby keeping the body aligned as designed, and keeping the pectoral and pelvic girdles aligned. Proper body alignment during use results in greater stability and equilibrium of the user compared to traditional “tri-pod” creating crutches.
US11020307B2	Assist system, assist method, and storage medium An assist system includes a fist belt worn on an upper body part of a user, a second belt worn on a knee of the user, a wire, a motor coupled with a first end of the wire and disposed on the first or second belt, a drive controller that controls drive of the motor, a gyro sensor that is disposed on the second belt and that measures an angular velocity about a direction perpendicular to the direction of the wire, and a controller. When the angular velocity is greater than or equal to a first threshold with a first tension being applied to the wire using the motor, the controller outputs first information. A second end of the wire is coupled with the second belt when the motor is disposed on the first belt but coupled with the first belt when the motor is disposed on the second belt.
US11020305B2	Canting mechanism for ambulatory support apparatus and method An apparatus for placing pressure on a plurality of trigger points includes a support, a first pressure element, and a second pressure element. The first pressure element is carried by the support. The second pressure element is carried by the support. The first pressure element is moveable with respect to the support, and the second pressure element is moveable with respect to the support. The first pressure element and the second pressure element are also moveable with respect to each other. The support has a length so that the support can be attached around a lower portion of the trunk of a human body. The first pressure element and the second pressure element are shaped to apply an external force to at least two portions of the human body proximate to where a psoas muscle, an Iliacus muscle, and a rectus femorus muscle intersect.
US11020302B2	Cushioned waterless sanitary toilet A toilet assembly includes a cushion defining a cushion niche and configured to be positioned under and support a backside of an individual. The toilet assembly also includes a waste collection receptacle having a receptacle body defining a sump configured to hold human waste. The waste collection receptacle is characterized by an external contour configured to selectively fit into the cushion niche and facilitate removal of the receptacle from the cushion niche when the cushion is positioned under the backside of the individual. The toilet assembly additionally includes a receptacle lid configured to be selectively opened to expose the sump and closed to hermetically seal the sump when the receptacle is positioned inside the cushion niche. A method of managing toiletry needs of an individual using the toilet assembly is also disclosed.
US11020300B2	Toilet safety arm accessory device A toilet safety arm accessory device comprises a frame that fits around a toilet and a pair of arms coupled thereto allows a user to apply a pulling force onto the device to allow the user to seat him or herself onto a toilet and/or to rise therefrom. The device, which the user grips in lowering and raising himself on and from the toilet. The device may be installed onto a toilet without the use of any tools or hardware and thus does not result in any damage, destruction, or other modification to or of the subject toilet. The toilet safety arm accessory device may also comprise elements of the device that may be added to existing toilet safety devices to allow a user to apply a pulling force and otherwise improve leverage needed to lower him or herself from a toilet and/or raise him or herself from a toilet.
US11020297B2	Powered side rail for a patient support apparatus A patient support system comprises a patient support apparatus for patients. The patient support apparatus comprises a base and a patient support surface supported by the base. The patient support apparatus also comprises side rails that move between raised and lowered positions. One or more actuators are coupled to each of the side rails. A controller communicates with the actuators to raise and lower the side rails, either without any manual assistance from the user, or with manual assistance from the user.
US11020295B2	Patient support systems and methods for assisting caregivers with patient care A patient support system comprises a patient support apparatus for patients. The patient support apparatus also comprises an actuatable device that perform one or more predetermined functions on the patient support apparatus. A controller is provided to control the rate of operation of the actuatable devices based on a user input or a patient condition.
US11020291B2	Absorbent article An object of the invention is to improve the diffusibility of body fluid such that the body fluid can be quickly absorbed. The sanitary napkin 1 represented by FIG. 3 includes an absorbing body 4 with a highly water-absorbent polymer 12 interposed between an upper layer sheet 10 disposed on the skin side and a lower layer sheet 11 disposed on the non-skin side. The upper layer sheet 10 has a plurality of first protrusions 14 forming first space parts 13 that are to be filled with the highly water-absorbent polymer and that expand to the skin side, and a plurality of second protrusions 16 forming second space parts 15, each of which having a smaller volume than each of the first space part 13, that are to be filled with the highly water-absorbent polymer and that expand to the skin side. The weight per unit area of the highly water-absorbent polymer 12 filled into the second space parts 15 is made smaller than the weight per unit area of the highly water-absorbent polymer 12 filled into the first space parts 13.
US11020288B2	Absorbent article having a graphic An absorbent article having a body contacting surface a garment contacting surface; and an absorbent core disposed therebetween is disclosed. The body contacting surface has first and second layers, with each layer having a pair of first longitudinal side edges and second longitudinal side edges, respectively. The garment contacting surface has a garment contacting layer with a plurality of graphic elements and a pair of garment layer longitudinal side edges. The absorbent core has a pair of core longitudinal side edges. Extending laterally outwardly from the article are a pair of flaps formed from a portion of the garment contacting layer and the second layer. A portion of a circumferential edge of the article is formed by each of the pair of second longitudinal side edges and the pair of garment layer longitudinal side edges.
US11020282B2	Method of producing a chassis web with a waistband component and disposable pant article produced from the chassis web A method for producing a chassis web for a disposable pant article, the method including feeding a first continuous base web in a machine direction; attaching a continuous elastic waistband component to the first base web in an attachment area extending in the machine direction; attaching a second continuous base web to the first continuous base web and the continuous waistband component, covering at least the continuous waistband component, thereby forming a compound base web having first and second side edges, the attachment area being spaced apart from at least one of the first and second side edges of the compound base web; severing the compound base web and the attached waistband component by cutting; shifting positions of the first panel web and the second panel web in a cross machine direction; forming a coherent chassis web.
US11020281B2	Method for forming stretchable structure for absorbent article and stretchable structure for absorbent article The present invention is intended to prevent cutting of the resilient and elastic members by a welding process. The foregoing issue is solved by passing a first sheet layer, a second sheet layer, and elongated resilient and elastic members continuously disposed in an MD direction between the two sheet layers, between a first roll with joint convex parts provided at circumferential intervals on an outer peripheral surface and a second roll opposed to the first roll, and pressurizing and heating the first sheet layer and the second sheet layer to form sheet joined sections by welding the first sheet layer and the second sheet layer in such a manner as to cross the resilient and elastic members and have MD-direction intervals therebetween, wherein circumferentially continuous grooves are formed on a pressurization surface of the second roll, passage sections of the resilient and elastic members are pressurized and heated in positions including the grooves of the second roll, and non-passage sections of the resilient and elastic members are pressurized and heated in positions not including the grooves of the second roll.
US11020273B2	Automated calibration of laser system and tomography system with fluorescent imaging of scan pattern A laser system calibration method and system are provided. In some methods, a calibration plate may be used to calibrate a video camera of the laser system. The video camera pixel locations may be mapped to the physical space. A xy-scan device of the laser system may be calibrated by defining control parameters for actuating components of the xy-scan device to scan a beam to a series of locations. Optionally, the beam may be scanned to a series of locations on a fluorescent plate. The video camera may be used to capture reflected light from the fluorescent plate. The xy-scan device may then be calibrated by mapping the xy-scan device control parameters to physical locations. A desired z-depth focus may be determined by defining control parameters for focusing a beam to different depths. The video camera or a confocal detector may be used to detect the scanned depths.
US11020269B2	Systems and methods for endotracheal delivery of frozen particles A treatment system delivers a breathing gas and frozen ice or other particles (FSP) to a bronchus of a lung of a patient in order to induce hypothermia. The breathing gas and the FSP are usually delivered through separate lumens. Clogging of an FSP lumen can be inhibited by heating and/or cooling of the lumen. The temperature of exhaled gases or a body temperature may be measured, and a controller can adjust the duration or rate at which the ice particles are delivered in order to control the patient's core temperature based on the measured temperature.
US11020262B2	Posture, performance, recovery garment device system A garment device and method of manufacture that to support proprioceptive posture rebalance and correction and athletic enhancement and allows and maintains breathability, functionality, range of motion, and aesthetic appeal.
US11020256B2	Bifurcated “Y” anchor support for coronary interventions Systems and methods to provide end to end stabilization support to the operational catheter and reduce the need to stabilize or push from the lateral wall of the aorta during coronary interventions. This reduces the potential for stroke from plaque breaking off the wall of the aorta during intervention procedures. A support and stabilization wire having one end at the femoral percutaneous access and the second end at a radial percutaneous access is established for end to end stabilization. A bifurcated catheter having a wide lumen for procedural catheters and a narrow lumen for the support wire or catheter is advanced over the support wire to the aortic arch. A procedural catheter and a variety of different shaped guide wires may be deployed from the wide lumen of the bifurcated catheter into the right or left coronary artery to accommodate a range of aortic anatomical considerations during the coronary interventions.
US11020250B2	Prosthetic and orthotic devices and methods and systems for controlling the same Prosthetic and/or orthotic devices (PODS), control systems for PODS and methods for controlling PODS are provided. As part of the control system, an inference layer collects data regarding a vertical and horizontal displacement of the POD, as well as an angle of the POD with respect to gravity during a gait cycle of a user of the POD. A processor analyzes the data collected to determine a locomotion activity of the user and selects one or more control parameters based on the locomotion activity. The inference layer may be situated between a reactive layer control module and a learning layer control module of the control system architecture.
US11020244B2	Bone harvester and bone marrow removal system and method A bone harvester and bone marrow removal system. The bone harvester can include a body defining a channel extending longitudinally therethrough from a distal to a proximal portion of the body. The distal portion can include a cutting tip. Bone marrow may be drawn through the channel.
US11020241B2	Expandable lateral spine cage with reverse dovetail configuration A spinal interbody implant includes a two-component cage and expander. The two-component cage, when assembled, accepts the expander through a reverse dovetail configuration between the assembled cage and the expander. The expander has a pair of legs that move within and along lateral channels formed by and between the two cage components for increasing the height of the two cage components relative to one another. The amount of expansion of the cage is determined by the height of the pair of expander legs. The cage accepts different expanders each having pairs of legs of different heights in order to provide different amounts of cage expansion and thus the interbody implant. The front of each expander leg is arch shaped for reception in the lateral channels of the assembled cage and to progressively expand the two cage components relative to one another as the expander is received by the assembled cage.
US11020237B2	Composite vertebral spacers and instrument An intervertebral fusion cage that is adapted to contain an inserter within its inner volume during insertion of the cage.
US11020233B2	Tapered fixation device for a knee replacement A fixation device for a knee replacement. The fixation device includes a stem configured to be fixedly attached to one of a tibial component of the knee replacement and a femoral component of the knee replacement. The stem has a continuously tapered outer surface and has a distal end that is distal to said one of the tibial component and the femoral component. A tapered projection is positioned on the continuously tapered outer surface and is tapered in the same direction as the continuously tapered outer surface. The stem and the tapered projection are configured so that the continuously tapered outer surface and the tapered projection engage a patient's bone when the stem is inserted into a bone canal within the patient's bone. In addition, the continuously tapered outer surface of the stem at the distal end of the stem and the tapered projection are configured to mechanically fix the knee replacement to the patient's bone by being wedged within the bone canal.
US11020228B2	Anchor delivery system and methods for valve repair Anchor delivery systems and methods for repairing a valve inside a body, such as a heart valve, may include a delivery catheter having a distal end comprised of two or more rotatably coupled knuckles. An anchor delivery mechanism is disposed distally of the two or more knuckles, and includes a first pincer arm having a distal end and a proximal end rotatably coupled to a distal end of the anchor delivery mechanism at a first connection point, and a second pincer arm having a distal end and a proximal end rotatably coupled to the distal end of the anchor delivery mechanism at a second connection point opposite the first connection point. In a closed position, the distal ends of the first and second pincer arms are positioned together. In an open position, the distal ends of the first and second pincer arms are rotated apart from each other.
US11020226B2	Prosthetic heart valve delivery system A valve prosthesis and a system for delivering a valve prosthesis are described herein. The system can include a core member and an engagement mechanism for releasably engaging a radially expandable valve anchor of the valve prosthesis along the core member. The engagement mechanism can include a pin assembly slidably coupled to the core member and a nose cone including a lock component slidably coupled along the core member to permit the valve anchor to disengage from the pin assembly.
US11020223B2	Transcatheter delivery system and method with controlled expansion and contraction of prosthetic heart valve A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached, includes a shaft assembly including a distal end and a coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve. The system includes a sheath assembly defining a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The coupling structure is configured to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve based on longitudinal movement of the distal end of the shaft assembly.
US11020219B2	Intraocular lens and manufacturing method thereof Provided is an intraocular lens having a novel structure with high utility which is easy to adapt to patients, and can improve quality of vision (QOV). In an intraocular lens, an optical characteristic is set rotationally symmetric around an optical axis, and a spherical aberration of a size corresponding to a coma aberration remaining in a patient's eye after extraction of a human lens of the eye is set.
US11020207B2	Orthodontic appliance for expansion of dentition An orthodontic appliance is disclosed that integrates an arch expander with a first segment and a second segment. The first and second segments are disposed on opposite sides of a midline of a dentition of an orthodontic patient. Both the first segment and the second segment are disposed over multiple teeth on the respective side of the midline, with a gap existing proceeding along the dentition between anterior-most portions of the first segment and the second segment. The arch expander is integrated with the first and second segments to exert an anteriorly-disposed expansion force on the patient's dentition through the first and second segments, for instance where the posterior-most location where these expansion forces are exerted corresponds with a first bicuspid on each side of a permanent the dentition.
US11020205B2	Providing a simulated outcome of dental treatment on a patient Systems and methods of simulating dental treatments are disclosed. A method may include capturing a first 2D image of a patient's face, including the patient's teeth, building a parametric 3D model of the patient's teeth based on the 2D image, developing a simulated outcome of a dental treatment of the patient's teeth by rendering the 3D model with the patient's teeth in one or more positions and/or orientations corresponding to the treatment goals of the dental treatment plan, and rendering a second 2D image of the patient's face with teeth according to a simulated outcome of the dental treatment plan. As noted herein, the dental treatment plan may include orthodontic and/or restorative elements. The simulated outcome may correspond to estimated outcomes and/or intended outcomes of the dental treatment plan.
US11020204B2	Virtually designing a customized healing abutment A method of virtually designing a customized healing abutment and a drill guide for a patient, where the method includes: obtaining a CT scan including at least part of the patient's jaw bone; virtually placing at least one implant relative to the jaw bone of the CT scan, such that a planned implant placement is defined; virtually designing: a drill guide for guiding the surgical drilling of a bore for the implant into the patient's jaw bone at the planned implant placement; and a customized healing abutment configured for shaping the soft tissue according to a target profile when arranged in the implant; where the design of the drill guide and of the customized healing abutment is at least partly based on the CT scan and on the planned implant placement.
US11020203B2	System for puncturing the epidermis with controlled fluid delivery Embodiments of an actuating device for actuating a needle cartridge and puncturing an epidermis with controlled depth. The actuating device includes a motor housed in a motor housing, an actuating rod driven by the motor and configured to actuate in a reciprocating motion, and an adjustment mechanism. The actuating rod is housed in a rod housing, the rod housing forming a device aperture configured to receive a needle cartridge and to attach to the needle cartridge. The adjustment mechanism interfaces with the rod housing and is configured to adjust a position of the rod housing relative to the motor housing while not rotating the rod housing relative to the motor housing.
US11020200B2	Surgical instrument with dual mode end effector and compound lever with detents A surgical instrument includes a body, an ultrasonic blade, a clamp arm assembly, and a detent assembly. The clamp arm assembly includes a clamp arm pivotably coupled with the body at a pivot assembly. The clamp arm is operable to compress tissue against the ultrasonic blade. The detent assembly is configured to provide tactile resistance to pivotal movement of the clamp arm relative to the body beyond a predefined pivot angle. The detent assembly is configured to permit pivotal movement of the clamp arm relative to the body beyond a predefined pivot angle upon application of a force sufficient to overcome the tactile resistance.

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