Document Document Title
US10995360B2 Use of aptamers in proteomics
The present invention is a method for measuring the amount of at least one molecule in a biological sample, the method comprising a) combining the sample, or a derivative thereof, with one or more aptamers and allowing one or more molecules in the sample to bind to the aptamer(s); b) separating bound from unbound molecules; and c) quantifying the molecule(s) bound to the or each aptamer, wherein quantification of the bound molecule(s) is carried out by sequencing at least part of the or each aptamer. Uses of and products derived from the method are also contemplated.
US10995358B2 Rapid antibiotic susceptibility test using membrane fluorescence staining and spectral intensity ratio improved by flow cytometry dead to live population ratio
Single dye fluorescent staining and the combination of differences in both intensity and spectral emission permit determination of the minimum concentration of an antibiotic needed to inactivate bacteria (Minimum Inhibitory Concentration (MIC)), thereby providing a means for rapid Antibiotic Susceptibility Testing (AST). This allows for a quick and easy means for clinicians to determine a suitable treatment regimen for patients suffering from bacterial infections and those that eventually lead to sepsis.
US10995350B2 Purine alkaloid-producing microorganisms and methods of making and using the same
Provided herein are microorganisms that include one or more heterologous nucleic acid selected from the group of a sequence encoding a 7-methylxanthosine synthase, a sequence encoding a theobromine synthase; and a sequence encoding a caffeine synthase, where the microorganism is capable of producing one or more purine alkaloid in a culture medium, when the microorganism is cultured under conditions sufficient to produce the one or more purine alkaloid. Also provided compositions and kits that include at least one of these microorganisms, and methods of producing one or more purine alkaloid that include culturing one of these microorganisms under conditions sufficient to produce the one or more purine alkaloid.
US10995345B2 Biological devices for producing oxidized zinc and applications thereof
Described herein are biological devices and methods for using the same to produce oxidized zinc. The biological devices include microbial cells transformed with a DNA construct containing genes for producing a zinc-related protein, an alkaline phosphatase, and an alcohol dehydrogenase. In some instances, the biological devices also include a gene for lipase. The oxidized zinc compositions produced herein have numerous applications.
US10995343B2 Wheat with new alleles of RHT-B1
The present invention provides a wheat plant comprising an Rht-B1 allele which encodes an Rht-B1 (DELLA) poly-peptide. Grain from a near-isogenic wheat line comprising the dwarfing Rht-B1c allele was subjected to sodium azide mutagenesis. Plants exhibiting early leaf elongation rates or mature plant height greater than the dwarf parent were selected and the Rht-B1 gene sequenced. This identified 35 mutated alleles of Rht-B1c. Similar methods were also used to identify mutant alleles of the dwarfing s1n1d allele in barley, where DELLA is encoded by the s1n1 gene.
US10995342B2 Rhg1 mediated resistance to soybean cyst nematode
Methods of increasing the resistance of plants, in particular soybeans, to nematodes, in particular soybean cyst nematodes, are provided herein. The methods include increasing the expression of Glyma18g02580, Glyma18g02590 and/or Glyma18g2610 in cells of a plant and in particular in root cells of a plant to increase the resistance of the plant and plant cells to nematodes. The methods include increasing the expression using constitutive promoters or by increasing the copy number of the polynucleotides. Constructs for expressing these polypeptides, transgenic cells, transgenic plants and methods of generating the same are also provided. Methods of screening plant cells for resistance or susceptibility to nematodes are also provided.
US10995340B2 Plant regulatory elements and uses thereof
The invention provides DNA molecules and constructs, and their nucleotide sequences, useful for modulating gene expression in plants, and for specifying intracellular or extracellular localization of a gene product of interest. Transgenic plants, plant cells, plant parts, and seeds, comprising the DNA molecules operably linked to heterologous transcribable polynucleotides are also provided.
US10995334B2 Treatment of nuclear factor (erythroid-derived 2)-like 2 (NRF2) related diseases by inhibition of natural antisense transcript to NRF2
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Nuclear factor (erythroid-derived 2)-like 2 (NRF2), in particular, by targeting natural antisense polynucleotides of Nuclear factor (erythroid-derived 2)-like 2 (NRF2). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of NRF2.
US10995330B2 Method for mobilizing immobilized cells
Method for producing mobility in immobile cells in in vivo or in vitro fertilization. The method includes producing mobility in individual immobile cells that are connected to a microstructure. The microstructure is composed at least partially of magnetic materials and a non-reciprocal movement of the microstructure with the immobile cell is executed by a time-varying, three-dimensional external magnetic field.
US10995328B2 Materials and methods for treatment of autosomal dominant cone-rod dystrophy
The present application provides materials and methods for treating a patient with autosomal dominant CORD, both ex vivo and in vivo; materials and methods for editing a GUCY2D gene in a human cell; and materials and methods for editing a R838H, R838C, or R838S mutation in a GUCY2D gene in a human cell. The present application also provides one or more gRNAs or sgRNAs for editing a GUCY2D gene; one or more gRNAs or sgRNAs for editing a R838H, R838C, or R838S mutation in a GUCY2D gene; and a therapeutic comprising at least one or more gRNAs or sgRNAs for editing a R838H, R838C, or R838S mutation in a GUCY2D gene. The present application provides a therapeutic for treating a patient with autosomal dominant CORD. The present application also provides a kit for treating a patient with autosomal dominant CORD. In addition, the present application provides a self-inactivating CRISPR-Cas system.
US10995316B2 Proline auxotrophs
The present disclosure provides compositions and methods for making and using methanotrophic proline auxotrophs.
US10995312B2 Biomanufacturing apparatus
Disclosed is biomanufacturing apparatus 1 comprising a housing 20 including top 22 and bottom 24 faces which allow stacking of plural housings, an access door 25 at a front side of the housing, a substantially enclosed bioreactor chamber 30 inside the housing accessible via the door, and a further substantially enclosed region 36 inside the housing containing electrical parts and/or electronic control components, the chamber 30 including: a tray 40 for supporting a bioreactor, a tray support 45 including a mechanism 44,47 for rocking the tray in use; at least a fluid handling portion 48,49 of at least one fluid pump device 54/58; and at least one connection 43 for connecting to a conduit and/or path for carrying fluids, gas and/or electricity.
US10995310B2 Biomanufacturing apparatus
Disclosed is biomanufacturing apparatus 1 comprising a housing 20 including top 22 and bottom 24 faces which allow stacking of plural housings, an access door 25 at a front side of the housing, a substantially enclosed bioreactor chamber 30 inside the housing accessible via the door, and a further substantially enclosed region 36 inside the housing containing electrical parts and/or electronic control components, the chamber 30 including: a tray 40 for supporting a bioreactor, a tray support 45 including a mechanism 44,47 for rocking the tray in use; the tray support further including a load cell (41) to determine changes in the mass load on the tray.
US10995309B2 Cell culture device and cell culture method
A cell culture device includes a storage tank having one or a plurality of cell culture units. The cell culture units includes a culture liquid main chamber having a circulation space through which a culture liquid of cells circulates, a permeable membrane having one surface to which the cells are able to adhere, said one face facing the circulation space, a first culture liquid storage chamber having an airtight structure in which the culture liquid is to be stored, a second culture liquid storage chamber in which the culture liquid is to be stored, a culture liquid introduction flow path that introduces the culture liquid from the first culture liquid storage chamber into the circulation space of the culture liquid main chamber, and a culture liquid lead-out flow path that introduces the culture liquid from the circulation space into the second culture liquid storage chamber.
US10995302B2 Liquid acidic hard surface cleaning compositions having improved viscosity
The need for an acidic hard surface cleaning composition which provides further improvements in the maintenance of surface shine, especially on inclined hard surfaces, while also using less thickener is met by formulating the acidic hard surface cleaning composition using a combination of a surface modification polymer and sulfonate hydrotrope.
US10995299B2 Self-lubricating polymer composition
A polymer resin composition is disclosed including a chemically attached lubricant structure to produce a self-lubricating medical device thereby eliminating the need of a secondary lubrication step currently required which is useful in medical and surgical devices.
US10995298B2 Self-lubricating polymer composition
A polymer resin composition is disclosed including a chemically attached lubricant structure to produce a self-lubricating medical device thereby eliminating the need of a secondary lubrication step currently required which is useful in medical and surgical devices.
US10995295B2 Use of lubricants on the basis of water-soluble, high viscosity polyglycols
The present invention relates to the use of lubricants on the basis of water-soluble, high-viscosity polyethylene glycols for lubricating open gearing, which is for example used in rotary kilns and mills.
US10995293B2 System and method for odorizing natural gas
The present disclosure provides a system and method for odorizing natural gas flowing through a distribution pipeline. The system includes a bypass line adjacent to a distribution pipeline, wherein bypass gas flows through the bypass line and an odorant tank connected to the bypass line, and into the distribution pipeline; a high-flow control valve and a low-flow control valve in the bypass line, wherein bypass gas flows through the odorant tank into the distribution pipeline when the high-flow control valve or the low-flow control valve is open; and a programmable logic controller connected to the high-flow and low flow control valve; wherein the programmable logic controller opens the high-flow or low-flow control valve for a predetermined dwell time proportional to an amount of bypass gas needed to odorize gas in the distribution pipeline each time that a preselected quantity of gas flows through the distribution pipeline.
US10995292B2 Nano perovskite materials as combustion improver for liquid and gaseous fuels
The present invention relates to use of Perovskite type of materials as combustion improver in gaseous and liquid fuels. Structurally, the Perovskite material consists of ABO3, AxB1-xCyO3 or AxB1-xCyO3 kind of material with stoichiometric deficiency and oxygen deficient sites. More particularly, the present invention relates to the nanosized perovskite materials stably dispersed in hydrocarbon medium and compatible to the fuel has been used to improve the combustion process and generate more heat output.
US10995291B2 Fuel compositions
Improved fuel compositions and fuel additive packages which serve to prolong stability at various ambient conditions and to increase fuel efficiency and fuel economy while also significantly reducing the level of multiple emissions constituents generated upon combustion of the fuels including CO2, NOX, SOX, Particulate Matter PM2.5, PM10 and Black Carbon. The fuels may include the hydrocarbon fuels gasolines, diesel fuels, biodiesel fuels, biomass diesel fuels, renewable fuels, synthetic fuels, algae-based fuels, kerosene fuel or heavy fuel oils, or may alternatively be hydrosols, and include an additive package having a sorbitan oleate, a polyoxyethylene alcohol, an alkylene glycol, and an amine. The fuels are mixed with an additive and are emulsified with clean, soft water having a water quality of 1 micron or less.
US10995289B2 Gasoline product containing combustion improver and manufacturing method therefor
Provided is a gasoline product containing a combustion improver, and a method for preparing the gasoline product. The combustion improver is added to gasoline to reduce an octane number and thus an ignition point of the gasoline, so that the gasoline product can be used in a compression ignition internal combustion engine. The combustion improver-containing gasoline product is a low-octane number gasoline, and is capable of being ignited through compression by an internal combustion engine having a compression ratio in the range from 12 to 22.
US10995288B2 Integrated process plant having a biomass reforming reactor using a fluidized bed
An interconnected set of two or more stages of reactors to form a bio-reforming reactor that generates syngas for a number of different liquid fuel or chemical processes is discussed. A first stage includes a circulating fluidized bed reactor that is configured to cause a chemical devolatilization of the biomass into its reaction products of constituent gases, tars, chars, and other components, which exit through a reactor output from the first stage. A second stage of the bio-reforming reactor has an input configured to receive a stream of some of the reaction products that includes the constituent gases and at least some of the tars as raw syngas, and then chemically reacts the raw syngas within a vessel of the second stage to make the raw syngas from the first stage into a chemical grade syngas by further cracking the tars, excess methane, or both.
US10995286B2 Catalytic dewaxing of hydrocarbon feedstocks
In a process for improving the cold flow properties of a hydrocarbon feedstock, the feedstock is contacted with a catalyst composition comprising an EMM-17 molecular sieve and a hydrogenation component under dewaxing conditions effective to produce a dewaxed product having a cloud point and/or pour point that is reduced relative to the cloud point and/or pour point of the feedstock by at least 5° C.
US10995284B2 Process for reducing the benzene content of gasoline
A process is described for reducing the level of benzene in a refinery gasoline feed containing benzene and at least one C5+ olefin, in which the refinery gasoline feed is contacted with a first alkylation catalyst under conditions effective to react at least part of the C5+ olefin and benzene in the refinery gasoline feed and produce a first alkylation effluent. The first alkylation effluent is separated into at least (i) a first fraction rich in benzene, (ii) a second fraction rich in C7 to C12 hydrocarbons and (iii) a third fraction rich in C13+ hydrocarbons. At least part of the first fraction is contacted with an alkylating agent comprising one or more C2 to C4 olefins in the presence of a second alkylation catalyst under conditions effective to produce a second alkylation effluent which has reduced benzene content as compared with the first fraction.
US10995279B2 Purification of oil
A method and a system for purification of contaminated oil. Said method comprises the steps of: —providing contaminated oil and a separation aid in a tank (3); —waiting for allowing a sludge phase comprising the separation aid together with impurities from the oil to settle in a bottom part (4) of the tank (3); —reusing the sludge phase for purification of new contaminated oil.
US10995278B2 Disposal of disulfide oil compounds and derivatives in delayed coking process
A heavy hydrocarbon oil is mixed with one or more disulfide oil compounds and/or one or more oxidized disulfide oil compounds and, optionally, a homogeneous catalyst includes dissolved hydrogen, and the mixture is subjected to a delayed coking process to produce a liquid coking unit product stream for recovery and further processing, with the delayed coking being completed in a reduced residence time as compared to the delayed coking of the heavy hydrocarbon oil without the DSO and/or ODSO compounds.
US10995277B2 System and method of predictive analytics for control of an overhead crude section of a hydrocarbon refining process
Described herein are systems and methods for control of an overhead crude section of a hydrocarbon refining process. In one aspect, the method comprises monitoring a plurality of operating conditions of an overhead crude section of a refinery; determining hydrogen chloride and amine conditions of the overhead crude section of the refinery at current operating conditions of the overhead crude section; determining a plurality of fields of action by simulating a variation of one or more of the plurality of conditions; determining a risk indicator of salting for each of the plurality of fields of action; and providing a recommended change in operation of the overhead crude section to one of the plurality of fields of action while adhering to one or more constraints.
US10995273B2 Polymerisable compounds and the use thereof in liquid-crystal displays
Polymerisable compounds, processes and intermediates for the preparation thereof, liquid-crystal (LC) media comprising them, and the use of the polymerisable compounds and LC media for optical, electro-optical and electronic purposes, in particular in LC displays, especially in LC displays of the polymer sustained alignment type.
US10995271B1 Bioorganic soil conditioner
The bioorganic soil conditioner includes biochar derived from plant waste and a mix of chemicals including sulfonated naphthalene formaldehyde, urea-formaldehyde and polyvinyl alcohol. The bioorganic soil conditioner is made by infusing biochar from lignin-rich plant waste with the mix of chemicals. The bioorganic soil conditioner improves soil aggregation and moisture and nutrient retention capacity. Thus, the bioorganic soil conditioner may be added to soil to improve crop production and stabilize soil, for example, in conditions of high wind or desertification.
US10995266B2 Electroluminescent material, method for manufacturing same, and light emitting device
The present application provides an electroluminescent material, a method for manufacturing the electroluminescent material, and a light emitting device, the asymmetric monocyanopyrazine of the pyrene nucleus of the electroluminescent material is used as an acceptor, and the pyrene nucleus has a large plane and rigid P-type delayed fluorescence characteristic, which can combine triplet excitons via triplet excitons-triplet excitons to enhance utilization of excitons, thereby to achieve an electroluminescent material, a method for manufacturing the electroluminescent material, and a light emitting device, to realize an electroluminescent material and a light emitting device with a high quantum efficiency.
US10995262B2 Ethoxylated amines for use in subterranean formations
Methods for treating subterranean formations are provided. In one embodiment, the methods comprise providing a treatment fluid comprising an aqueous base fluid and a surfactant comprising an ethoxylated amine or derivative thereof; introducing the treatment fluid into a wellbore penetrating at least a portion of a subterranean formation; and producing fluids from the wellbore during or subsequent to introducing the treatment fluid into the wellbore.
US10995261B2 Surfactant flowback aids for use in subterranean formation operations
The embodiments herein relate generally to subterranean formation operations and, more particularly, to surfactant flowback aids for use in subterranean formation operations. The surfactant flowback aid composition may comprise an aqueous phase comprising an aqueous base fluid, a surfactant blend, and a demulsifier. The surfactant blend may comprise a C8-C18 alcohol ethoxy-late; a fatty acid alkanolamide; and optionally, a surfactant selected from the group consisting of a non-ionic surfactant, an anionic surfactant, a cationic surfactant, an amphoteric surfactant, and any combination thereof. The demulsifier may be selected from the group consisting of a desalter agent to separate water from crude oil, a treater agent to flocculate submicron particulates from crude oil, and any combination thereof.
US10995259B2 Low density gas hydrate inhibitor
A method of inhibiting gas hydrate formation in downhole fluids, including providing a downhole fluid and mixing the downhole fluid with an aqueous gas thermodynamic hydrate inhibitor formulation to form a downhole fluid mixture. A concentration of lithium chloride in the downhole fluid mixture is at least about 1 wt % and a density of the downhole fluid mixture is in a range of about 1.08 to 1.3 gm/cm3 at a downhole temperature of about 50° F. or less and a downhole differential pressure of about 500 psi or higher. An aqueous gas thermodynamic hydrate inhibitor formulation and oil and gas well drilling system including such a formulation are also disclosed.
US10995257B2 Process to produce oil or gas from a subterranean formation using a chelating agent
A two-step process to produce oil or gas from a subterranean formation wherein in a first step the subterranean formation is treated with an aqueous composition containing a chelating agent selected from the group of glutamic acid N,N-diacetic acid or a salt thereof (GLDA), aspartic acid N,N-diacetic acid or a salt thereof (ASDA), methylglycine N,N-diacetic acid or a salt thereof (MGDA), and N-hydroxyethyl ethylenediamine N,N′,N′-triacetic acid or a salt thereof (HEDTA) and wherein, in a next step, in the outlet streams from the subterranean formation the aqueous phase is separated from the non-aqueous phase.
US10995256B2 Lost circulation material compositions and methods of isolating a lost circulation zone of a wellbore
A lost circulation material (LCM) composition for sealing a lost circulation zone in a wellbore is disclosed that includes from 50 weight percent to 97 weight percent epoxy resin and from 2 weight percent to 30 weight percent curing agent. The epoxy resin may include at least one of 2,3-epoxypropyl o-tolyl ether, alkyl glycidyl ethers having from 12 to 14 carbon atoms, bisphenol-A-epichlorohydrin epoxy resin, or a compound having formula (OC2H3)—CH2—O—R1—O—CH2—(C2H3O), where R1 is a linear or branched hydrocarbyl having from 4 to 24 carbon atoms. A method for isolating a lost circulation zone using the LCM compositions is also disclosed and includes introducing a spacer fluid to the lost circulation zone, introducing the LCM composition to the lost circulation zone, and curing the LCM composition in the lost circulation zone to isolate the lost circulation zone.
US10995255B2 Method of inhibiting water penetration into oil- and gas-producing formations
Water penetration into a siliceous subterranean hydrocarbon fluid-bearing formation is inhibited by introducing into the formation organosiloxane possessing at least one alkoxy group directly bonded to a silicon atom.
US10995253B2 Lithium-containing calcium aluminate phosphate cement admixtures
Lithium-containing cement admixtures including a calcium aluminate phosphate cement; a lithium-ion-containing compound; and an aqueous base fluid and methods of introducing the lithium-containing cement admixtures into a subterranean formation. The lithium-containing cement admixtures may further comprise an aluminosilicate or an additive including a set retarder, a set accelerator, a suspension aid, a density reducing agent, a fluid loss control agent, a defoamer, and any combination thereof.
US10995252B2 Vinyl alcohol polymer and cement slurry comprising same
Provided is a vinyl alcohol polymer having good fluid loss reducing performance. The vinyl alcohol polymer is a saponified product of a copolymer of a vinyl ester monomer and a multifunctional monomer, and has a degree of saponification of 70 to 95 mol % and a viscosity-average degree of polymerization of 1000 to 10000.
US10995251B2 Method and material for isolating a severe loss zone
A method and drilling fluid additive for reducing severe fluid losses in a well, comprising a combination of granular scrap tire particles and polymer adhesive molded into a capsule shape. Once in the severe loss zone, a plurality of LCMs wedge into the formation fractures and seal off the severe loss zone.
US10995250B2 Thermal storage system
A thermal storage composition is defined by a polymer having thermally responsive absorption or passage capabilities based on an Upper Critical Solution Temperature (UCST) or Lower Critical Solution Temperature (LCST), and a sorbent in fluidic communication with the polymer. A fluid such as water conveys thermal energy between the polymer and the sorbent based on an identified target temperature that acts as a thermostat for synergistic fluid release and transfer between the polymer and sorbent that stores and releases heat energy in a cyclic manner. The composition includes a synergistic integration of a sorbent and selectively hydrophilic polymer to alternately hydrate according to a target temperature based on the UCST of the water/sorbent combination.
US10995249B2 Tire with reduced cavity noise
Disclosed is a tire with reduced cavity noise including an adhesive agent layer applied to an inside of an inner liner and a sound absorber layer attached to the adhesive agent layer, wherein the adhesive agent layer includes polyether containing alkoxysilane at both ends thereof and a benzotriazole-based UV absorber. The tire with reduced cavity noise is stable without causing separation of a sound absorber even upon heating and deformation during driving.
US10995245B2 Epoxy resin composition and electro-conductive adhesive containing the same
An epoxy resin composition which exhibits excellent storage stability while having a low initial viscosity and favorable low temperature curability and an electro-conductive adhesive containing the same. An epoxy resin composition includes components (A) to (C): component (A): an epoxy resin (excluding the following component (B)); component (B): an epoxy resin having one epoxy group in a molecule and a surface tension of from 28.5 to 35.0 mN/m; and component (C): a latent curing agent.
US10995242B2 Coating system for coating a surface of a substrate
Coating system (1) for coating a surface (3) of a substrate (5), the coating system (1) comprising; a coating (7), and an adhesive layer (9), that is disposed between the substrate (5) and the coating (7), wherein the adhesive layer (9) comprises a first adhesive layer portion (13) adjacent the substrate (5) and a second adhesive layer portion (15) adjacent the coating (7) and a carrier (11) placed between said first and second adhesive layer portions (13, 5), wherein the first adhesive layer portion (13) is composed of a first adhesive layer material, wherein the second adhesive layer portion (15) is composed of a second adhesive layer material, wherein the first adhesive layer material and the second adhesive layer material is having an adhesive or bond strength to the surface (3) of the substrate (5) and to the coating (7) respectively that exceeds their respective cohesive or tensile strength, wherein the first and second adhesive layer materials and carrier (11) combination is configured for having an adhesive strength that is less than their respective cohesive or tensile strength, wherein the carrier (11) is configured with grab tensile properties such that the carrier (11) in combination with the second adhesive layer portion (15) and the coating (7) will separate from the first adhesive layer portion (13) under the action of a peeling force.
US10995241B2 Adhesive tape cartridge, adhesive tape roll, and method of manufacturing an adhesive tape roll
The disclosure discloses an adhesive tape cartridge including an adhesive tape roll. The adhesive roll winds an adhesive tape around a predetermined axis in a housing. The adhesive tape includes a base layer, a first particle-containing adhesive layer, and a second particle-containing adhesive layer. The first particle-containing adhesive layer is disposed on a first side of the base layer in a thickness direction and comprises an adhesive to which particles are added. The second particle-containing adhesive layer is disposed in contact with a surface on the first side of the first particle-containing adhesive layer in the thickness direction and comprises an adhesive to which particles of the same material as the particles are added.
US10995239B2 Polishing fluid for improving surfaces formed by fused deposition molding with abs and method of preparing same
Disclosed is a polishing fluid for improving surfaces formed by fused deposition molding with ABS, consisting of 30%-40% by weight of polymethyl methacrylate and 60%-70% by weight of a mixture. This application further discloses a method of preparing the polishing fluid by mixing under heating. The polishing fluid provided herein can quickly form a film on surfaces of the workpiece to be processed and fill depressions of the surfaces of the workpiece while dissolving the protrusions on the surfaces to render the surfaces smooth and even.
US10995238B2 Neutral to alkaline chemical mechanical polishing compositions and methods for tungsten
A neutral to alkaline chemical mechanical composition for polishing tungsten includes, as initial components: water; an oxidizing agent selected from an iodate compound, a periodate compound and mixtures thereof; colloidal silica abrasive particles including a nitrogen-containing compound; optionally, a pH adjusting agent; and, optionally, a biocide. The chemical mechanical polishing method includes providing a chemical mechanical polishing pad, having a polishing surface; creating dynamic contact at an interface between the polishing pad and the substrate; and dispensing the neutral to alkaline chemical mechanical polishing composition onto the polishing surface at or near the interface between the polishing pad and the substrate; wherein some of the tungsten is polished away from the substrate and, further, to at least inhibit static etch of the tungsten.
US10995236B2 Polyurethane coating composition
A coating composition, coated article and method for coating an article are provided. The composition is a coating composition that includes a polyurethane binder system further including a first resin component and a second resin component with a significant difference in hydroxyl numbers and crosslinked with an isocyanate. The composition, when applied to and cured on an article, imparts optimal antifingerprint, antireflecting, tactile, chemical agent-resistant, and self-healing effects to the coated article.
US10995235B2 Composition for forming protective film for electroconductive pattern, protective film for electroconductive pattern, method for producing protective film, and method for producing transparent electroconductive film
A composition for a protective film for electroconductive patterns, including: (A) a polyurethane containing a carboxyl group; (B) an epoxy compound; (C) a curing accelerator; and (D) a solvent, wherein the percentage of the solvent (D) contained is from 95.0% to 99.9% by mass, and the solvent (D) contains (D1) a solvent containing a hydroxyl group and having a boiling point in excess of 100° C., and (D2) a solvent having a boiling point that does not exceed 100° C., wherein the content of the solvent (D2) having a boiling point that does not exceed 100° C. is 30% to less than 70% by mass of total solvent in total. The composition can be cured by heating at a temperature not exceeding 100° C. for a heating time not exceeding 10 minutes.
US10995233B2 Water-resistant acrylic coatings
Water-resistant waterborne acrylic coating materials, systems and methods providing enhanced water resistance and durability are provided. Such coatings extend the service life of roofing systems that are exposed to ponding water and other extreme weather conditions. Coatings described herein exhibit superior water resistance attributes including one or more of water infiltration resistance, wet tensile strength and wet adhesion.
US10995232B2 Flexible conductive ink
This invention is a flexible conductive ink composition comprising (A) a resin binder, (B) silver-plated core conductive particles, and (C) conductive particles having a surface area at least 1.0 m2/g.
US10995230B2 Aqueous pigment ink for textile inkjet printing, method for producing printed textile item, and ink set
An aqueous pigment ink for textile inkjet printing is disclosed that contains a pigment, a first water-dispersible resin, a second water-dispersible resin and water, wherein the first water-dispersible resin is at least one resin selected from the group consisting of a water-dispersible urethane resin, a water-dispersible (meth)acrylic resin and a water-dispersible styrene/(meth)acrylic resin, the second water-dispersible resin is a water-dispersible polyester resin, the total amount of the first water-dispersible resin and the second water-dispersible resin is from 2 to 18% by mass relative to the total mass of the ink, and the mass ratio of the second water-dispersible resin relative to the first water-dispersible resin (second water-dispersible resin/first water-dispersible resin) is from 0.1 to 5.0. A method for producing a printed textile item and an ink set are also disclosed.
US10995228B2 Hollow structure particles, method for producing same and white ink
Hollow structure particles which contain titanium oxide and silica, in which the crystal type of the titanium oxide is rutile type; a method for producing the hollow structure particles; a white ink which contains these hollow structure particles as a coloring agent; use of the white ink in inkjet recording; and an inkjet recording method which uses the white ink.
US10995226B2 Active-energy-ray-curable composition, active-energy-ray-curable ink composition, composition stored container, two-dimensional or three-dimensional image forming apparatus, method for forming two-dimensional or three-dimensional image, cured product, and laminated cured product
An active-energy-ray-curable composition including at least one monofunctional (meth)acrylate, at least one multifunctional (meth)acrylate, and at least one chlorinated-olefin-structure-containing polymer.
US10995225B2 Macrocyclic polyphenols for universal coatings
The disclosure provides for coating compositions comprising macrocycles and salts in aqueous buffer and the use of the coating composition to prevent absorption of small molecules into polymeric surfaces.
US10995223B2 Fibrous carbon nanostructure dispersion liquid
A fibrous carbon nanostructure dispersion liquid having excellent dispersibility of fibrous carbon nanostructures is provided. A fibrous carbon nanostructure dispersion liquid comprises: fibrous carbon nanostructures with a tap density of 0.024 g/cm3 or less; and a solvent.
US10995221B2 Fire retardant-treated wood products with durable coating protection
A novel method of improving the water and leaching resistances and durability of a fire retardant-treated wood product by using a chemical fire retardant composition in which crosslinking polyvinyl acetate (XPAVc or X-PVAc) is applied as a protective coating on wood over the fire retardant layer. An additional crosslinking polyvinyl acetate coating layer or one or more layers of acrylic, alkyd, epoxy, lacquer, polyester, polyurethane, silicone coatings, vinyl ester, or the like may further cover the cured crosslinking polyvinyl acetate primer and then dried or cured.
US10995220B2 Functionalized quaternary ammonium halides and use thereof
Provision of hydroxyl group functionalized quaternary ammonium halides, photocurable or hydrolytically curable urethane based polymers thereof and their use as antifouling agents.
US10995219B2 Free radical-curable coating and sealant compositions with improved surface cure properties
Inhibition by oxygen of the peroxide-initiated cure of a composition based on (meth)acrylates or other compounds containing free radical-polymerizable functional groups is mitigated by inclusion of one or more polythiols in the composition. Such compositions may be formulated as multi-part systems, which are useful for the preparation of coatings and sealants.
US10995216B2 Silicone rubber composite and method for producing same
In the present invention, it is possible to provide a silicone rubber composite which exhibits a conductivity equal to or higher than that using a high content of carbon black, by using a low content of carbon nanotubes as a conductive filler instead of a high content of carbon black to impart conductivity to insulating silicone rubber.
US10995215B2 Fluoromonomer and fluorooligomer compounds, photopolymerizable composition, and hydrophobic film using the same
The present disclosure relates to novel fluoromonomer and fluorooligomer compounds, a photopolymerizable composition including these compounds, methods for producing these compounds, and a hydrophobic film using the photopolymerizable composition.
US10995213B2 Polycarbonate resin composition and molded polycarbonate resin
Provided is a polycarbonate resin composition capable of providing a molded body that has a high light transmittance and high light-diffusing property, can be inhibited from yellowing, and has high thin-wall flame retardancy, and a polycarbonate resin molded body obtained by molding the polycarbonate resin composition. The flame-retardant light-diffusing polycarbonate resin composition has a viscosity-average molecular weight of 17,000 or more and includes, with respect to 100 parts by mass of a polycarbonate (A) formed of 10 to 100 parts by mass of a branched polycarbonate (A-1) and 90 to 0 parts by mass of an aromatic polycarbonate (A-2), 0.1 to 5 parts by mass of a light diffuser (B), 0.01 to 1.0 part by mass of a flame retardant (C), 0 to 0.5 part by mass of a polytetrafluoroethylene (D), and 0 to 2 parts by mass of a polyorganosiloxane (E), and the polycarbonate resin molded body is obtained by molding the polycarbonate resin composition.
US10995211B2 Oxygen-absorbing resin composition containing organic oxygen absorber
An oxygen-absorbing resin composition containing an ethylene terephthalate type polyester resin and an organic oxygen absorber and, further, containing cobalt in an amount of 5 to 50 ppm and titanium in an amount of 1 to 15 ppm calculated as elements.
US10995201B2 Articles formed with biodegradable materials and strength characteristics of the same
Described herein are strength characteristics and biodegradation of articles produced using one or more petrochemical-based polymers and one or more carbohydrate-based polymers. A compatibilizer can optionally be included in the article. In some cases, the article can include a film or bag.
US10995200B2 Kaolin clay for thermoplastic resin composition and thermoplastic resin composition
Provided are a kaolin clay for a thermoplastic resin composition that can provide high impact strength and glossiness and a thermoplastic resin composition containing the same. A kaolin clay for a thermoplastic resin composition is subjected to a surface treatment with 0.2 to 10 parts by mass of at least one selected from the group consisting of methyl silicate, ethyl silicate, propyl silicate, and butyl silicate relative to 100 parts by mass of the kaolin clay.
US10995194B2 Filled elastomers with improved thermal and mechanical properties
The invention relates to elastomeric compositions containing filler particles that are predominantly two-dimensional in shape. The elastomeric compositions exhibit significantly improved thermal, chemical, and mechanical properties as compared with elastomers containing conventional fillers such as natural clay, carbon black, and carbon fiber. In addition, the elastomeric compositions of the invention exhibit improved resistance to solvent-induced swelling and to unwanted permeation of gases such as hydrogen sulfide. The invention also provides a method of forming such elastomeric compositions and methods of using such elastomeric compositions to prepare elastomeric articles with improved resistance to thermal, chemical, and mechanical stresses.
US10995193B2 Liquid modified PET polyesters for lithographic inks
The present invention is directed to a method of making liquid polyester resins, and the liquid polyester resins produced by the method. The liquid polyester resins are prepared by depolymerizing virgin, scrap, recycled or reclaimed polyethylene terephthalate (PET) via an alcoholysis reaction with one or more mono-alcohols and/or polyols; transesterifying the resulting polyol oligomer with vegetable oils or fatty acid alkyl esters; and re-polymerizing with acids or anhydrides. The present invention also provides ink and coating compositions, and overprint varnishes, comprising the liquid polyester resins of the invention.
US10995192B2 Composite material reinforced by foamed skeleton and preparation method and uses thereof
A foamed skeleton reinforced composite, comprising a foamed skeleton and a matrix material. The foamed skeleton is selected from at least one of a metal foamed skeleton, an inorganic non-metal foamed skeleton, and an organic foamed skeleton. The matrix material is selected from a metal or a polymer.
US10995191B2 High optical transparency polymer aerogels using low refractive index monomers
A polymer aerogel has polymerizable monomers and crosslinkers, wherein at least one of the monomers or at least one of the crosslinkers has a refractive index of less than 1.5, and the polymer aerogel has a visible transmittance of at least 20%/3 mm, a haze of 50%/3 mm or lower, and a porosity of at least 10%. A method of producing an aerogel includes dissolving precursors into a solvent, wherein the precursors include monomers, crosslinkers, a controlling agent and an initiator to form a precursor solution, wherein at least one of the monomers or at least one of the crosslinkers has a refractive index of 1.5 or lower, polymerizing the precursor solution to form a gel polymer, and removing the solvent from the gel polymer to produce an aerogel polymer.
US10995189B2 Resin composition and applications thereof
A resin composition contains an ethylene-vinyl alcohol copolymer (A) in which an ethylene unit content is from 10 to 60 mol %, a hindered amine-based compound (B) having a 2,2,6,6-tetraalkylpiperidine ring structure and having an alkoxy group bonded to a nitrogen atom in the structure, and a hindered phenol-based compound (C) having an ester bond or an amide bond. The resin composition contains 0.1 to 5 parts by mass of the hindered amine-based compound (B) and 0.2 to 5 parts by mass of the hindered phenol-based compound (C) with respect to 100 parts by mass of the ethylene-vinyl alcohol copolymer (A), and a mass ratio (C)/(B) is from 0.2 to 3.6.
US10995187B2 Composite structure having nanoparticles for performance enhancement
A composite structure includes a resin, a plurality of polymer nanoparticles in the resin to form a resin mixture, and a plurality of reinforcing fibers embedded within the resin mixture. At least some of the polymer nanoparticles are either fully soluble in the resin during curing or solidifying of the resin mixture to form a cured composite structure, or semi-soluble in the resin during curing or solidifying of the resin mixture to form the cured composite structure.
US10995185B2 Masterbatch compositions having titanium dioxide and propylene-ethylene copolymer
Wax-free masterbatch compositions and methods of formulation thereof for use in the production of various end-use plastic products. The wax-free masterbatch compositions may comprise at least titanium dioxide and propylene-ethylene copolymer, and optionally, a carrier resin. The propylene-ethylene copolymer may have about 6% to about 20% by weight ethylene content.
US10995184B2 Sol composition, aerogel composite, support member provided with aerogel composite, and heat insulator
The present invention relates to a sol composition for forming an aerogel composite, wherein the sol composition is a sol composition with a sufficient pot life for forming an aerogel composite superior in thermal insulation and flexibility, and comprises: at least one selected from the group consisting of a silicon compound having a hydrolyzable functional group or a condensable functional group and a hydrolysis product of the silicon compound having a hydrolyzable functional group; and a silica particle having an average primary particle diameter of 5 to 300 nm or a specific surface area of 10 to 600 m2/g.
US10995180B2 Polyetherimide compositions, methods of manufacture, and articles prepared therefrom
A polyetherimide composition includes a polyetherimide and two or more of a residual metal content, a sulfate anion, a phosphate anion, a nitrite anion, a nitrate anion, or a combination including at least one of the foregoing, a residual solvent content, a phosphorus-containing stabilizer, and alkali metal halide, alkaline earth metal halide, alkali metal carbonate, or a combination including at least one of the foregoing, wherein each of the aforementioned components, when present, is included in the composition in a particular amount. The resulting polyetherimide composition exhibits two or more useful properties. The polyetherimide composition can optionally further be combined with a polymer different from the polyetherimide to provide a thermoplastic composition. Methods of making the polyetherimide composition and articles including the polyetherimide composition are also described.
US10995179B2 Polyimide resin and metal-clad laminate comprising the same
The present disclosure provides a polyimide resin having at least two glass transition temperatures measured by dynamic mechanical analysis (DMA). Also, a metal-clad laminate including the polyimide resin.
US10995174B2 Production of polyurethane systems
The invention provides a process for production of polyurethane systems by reacting at least one polyol component with at least one isocyanate component in the presence of one or more catalysts for the isocyanate-polyol and/or isocyanate-water reactions and/or the trimerization of isocyanate, wherein said reacting is carried out in the presence of carrier material and polyamine P.
US10995170B2 Branched ethylene copolymers produced via use of vinyl transfer agents and processes for production thereof
This invention relates to the use of pyridyldiamido and/or quinolinyldiamido transition metal complexes and catalyst systems with an activator and a metal hydrocarbenyl chain transfer agent, such as an aluminum vinyl-transfer agent (AVTA), to produce branched ethylene copolymers, preferably ethylene-butene, ethylene-hexene and ethylene-octene copolymers.
US10995169B2 Polyethylene for pipes
The present invention provides a process for the preparation of a multimodal polyethylene comprising: (i) polymerising ethylene and optionally an α-olefin comonomer in a first polymerisation stage to produce a first ethylene polymer; and (ii) polymerising ethylene and optionally an α-olefin comonomer, in the presence of said first ethylene polymer, in a second polymerisation stage, wherein the first and second polymerisation stages are carried out in the presence of an unsupported metallocene catalyst and each polymerisation stage produces at least 5% wt of the multimodal polyethylene, and the multimodal polyethylene has a multimodal molecular weight distribution, a molecular weight of at least 50,000 g/mol and a bulk density of at least 250 g/dm3, and wherein a solution of the unsupported metallocene catalyst in a solvent is employed. The present invention also provides a multimodal polyethylene, a process for preparing a pipe comprising preparing a multimodal polyethylene and extruding the multimodal polyethylene to produce a pipe, and a pipe obtained by such a process.
US10995168B2 Process for the preparation of ethylene polymers using a number of reactors arranged in series
The present invention relates to a process for the preparation of ethylene polymers using a number of reactors arranged in series comprising the steps in which a) ethylene, a diluent, a catalyst, a co-catalyst and optionally comonomers and hydrogen are introduced into a first reactor, b) polymerization of ethylene and optionally comonomers is carried out in the reaction mixture of said first reactor to make ethylene polymers, c) reaction mixture is discharged from said first reactor, d) said reaction mixture and fresh ethylene and optionally comonomers and hydrogen are introduced into the consecutive reactor to make additional ethylene polymers, e) said reaction mixture is discharged from said consecutive reactor and introduced into the further consecutive reactor, if any, with fresh ethylene and optionally comonomers and hydrogen to make additional ethylene polymers, steps c) and d) are repeated until the last reactor of the series, f) reaction mixture is discharged from last reactor of the series and ethylene polymers are recovered, wherein, additional co-catalyst is injected in at least a subsequent reactor of the series. Advantage of the process of the present invention is mainly to decrease catalyst consumption for the same polyethylene production, in other words to increase the productivity. In a most preferred embodiment the process of the present invention is carried out in two loop reactors under slurry conditions.
US10995166B2 Ethylene interpolymer products and films
This disclosure relates to ethylene interpolymer compositions and films prepared therefrom. Specifically: ethylene interpolymer products having: a dimensionless Long Chain Branching Factor, LCBF, greater than or equal to 0.001; a residual catalytic metal of from ≥0.03 to ≤5 ppm of hafnium, and; a dimensionless unsaturation ratio, UR, of from ≥−0.40 to ≤0.06, wherein UR is defined by the following relationship; UR=(SCU−TU)/TU, where SCU is the amount of a side chain unsaturation per 100 carbons and TU is amount of a terminal unsaturation per 100 carbons, in said ethylene interpolymer product. The disclosed ethylene interpolymer products have a melt index from about 0.3 to about 500 dg/minute, a density from about 0.855 to about 0.975 g/cc, a polydispersity (Mw/Mn) from about 1.7 to about 25 and a Composition Distribution Breadth Index (CDBI50) from about 1% to about 98%.
US10995164B2 Method of forming thermoresponsive polymers
A method of forming a thermoresponsive polymer. The method proceeds by mixing 2-(3-(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)ureido)ethyl methacrylate and methacrylamide in the presence of a solvent form a monomer solution. An initiator is then added to the monomer solution to form a thermoresponsive polymer.
US10995158B2 Process for manufacture of low emission heterophasic polypropylene
The invention relates to a process for the preparation of a heterophasic propylene copolymer consisting of a propylene-based matrix and a dispersed ethylene-a-olefin copolymer, comprising the steps of a) preparing the propylene-based matrix from propylene and optionally a C2 or C4-C12 α-olefin by contacting at least propylene and optionally C2 or C4-C12 a-olefin with a catalyst in a first gas-phase reactor at a temperature T1 and a pressure P1, b) subsequently preparing the dispersed ethylene-α-olefin copolymer from ethylene and a C3-C12 α-olefin by contacting the ethylene and the C3-C12 α-olefin with a catalyst in a second gas-phase reactor at a temperature T2 and a pressure P2, wherein T1-T2 is in the range from 6 to 25° C., wherein T1>T2, wherein PI and P2 are in the range from 22 to 30 bar to prepare a heterophasic propylene copolymer (A′).
US10995156B2 Acid-degradable and bioerodible modified polyhydroxylated materials
Compositions and methods of making a modified polyhydroxylated polymer comprising a polyhydroxylated polymer having reversibly modified hydroxyl groups, whereby the hydroxyl groups are modified by an acid-catalyzed reaction between a polydroxylated polymer and a reagent such as acetals, aldehydes, vinyl ethers and ketones such that the modified polyhydroxylated polymers become insoluble in water but freely soluble in common organic solvents allowing for the facile preparation of acid-sensitive materials. Materials made from these polymers can be made to degrade in a pH-dependent manner. Both hydrophobic and hydrophilic cargoes were successfully loaded into particles made from the present polymers using single and double emulsion techniques, respectively. Due to its ease of preparation, processability, pH-sensitivity, and biocompatibility, of the present modified polyhydroxylated polymers should find use in numerous drug delivery applications.
US10995154B2 Environmentally friendly process for the preparation of nanocellulose and derivatives thereof
The present disclosure relates to the environmentally preparation of nanocellulose and derivatives thereof. The invention further relates to the preparation of cellulose derivatives.
US10995153B2 Polypeptide selectively binding to immunoglobulin G of mouse or rabbit and use thereof
The present invention relates to a novel polypeptide that binds selectively to mouse or rabbit immunoglobulin G. More specifically, the present invention relates to a polypeptide that binds to mouse or rabbit immunoglobulin G, a polynucleotide encoding the polypeptide, an expression vector comprising the polynucleotide, a transformant introduced with the expression vector, a method of producing the polypeptide using the transformant, and a composition for immunoassay comprising the polypeptide. The novel peptide according to the present invention binds specifically to mouse or rabbit immunoglobulin G, can replace conventional expensive secondary immunoglobulin G, and can be used in various biological immunoassays. In addition, a conjugate of the polypeptide of the present invention and immunoglobulin G is useful for fabrication of various immunosensors/immunochips and for drug screening.
US10995151B1 Methods and compositions for treating disease-related cachexia
A method of treating disease-related cachexia comprises administering to a subject a composition comprising an anti-AGE antibody. A composition for treating disease-related cachexia comprises a first anti-AGE antibody, a second anti-AGE antibody and a pharmaceutically acceptable carrier. The first anti-AGE antibody is different from the second anti-AGE antibody. A method of treating or preventing the onset of disease-related cachexia comprises immunizing a subject in need thereof against AGE-modified proteins or peptides of a cell.
US10995150B2 Methods for inhibiting atherosclerosis by administering an anti-PCSK9 antibody
The present invention provides methods and compositions for inhibiting atherosclerotic plaque formation in a subject. In certain embodiments, the methods of the present invention comprise selecting a subject who has, or is at risk of developing, atherosclerosis, and administering to the subject a pharmaceutical composition comprising a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody, or antigen binding protein.
US10995149B2 Antibodies that specifically bind PD-1 and methods of use
Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.
US10995145B2 Antibodies which bind human glucagon receptor
The present disclosure provides binding proteins, such as antibodies, that bind glucagon receptors, including a human glucagon receptor, and methods of their use.
US10995141B2 Modified anti-PD-L1 antibody and methods and uses for treating a neurodegenerative disease
The present specification discloses modified anti-PD-L1 antibodies that abolishes Fc-related effector function and enhances clearance rate while maintaining therapeutic efficacy for neurodegenerative disease modification. The present specification also discloses nucleic acid sequences and expression constructs encoding such modified anti-PD-L1 antibodies as well as methods of making such modified anti-PD-L1 antibodies. In addition, the present specification discloses methods of treatment and uses that employ an administration regime of the disclosed anti-PD-L1 antibodies that ensures the antibodies are present for only a specific period of time and then are sufficiently cleared from the body to ensure treatment efficacy is maintained.
US10995140B2 GM-CSF/CD40L vaccine and checkpoint inhibitor combination therapy
A method is disclosed for treating a cancer in a subject. The method comprises administering to the subject a composition comprising a therapeutically effective amount of a checkpoint inhibitor and a therapeutically effective amount of a tumor vaccine. In some embodiments, the tumor vaccine comprises radiated autologous tumor cells and a cell line engineered to express GM-CSF and CD40 ligand. In some embodiments, the checkpoint inhibitor comprises an anti-PD-1 antibody (e.g., BMS 936558), anti-PD-L1 antibody (e.g., cloneM1H1), anti-CTLA-4 antibody (e.g., Ipilimumab, BMS), or any combination thereof.
US10995139B2 Interleukin-10 receptor-2 peptides, antibodies, compositions, and methods of use thereof
Described herein are interleukin-10 receptor-2 peptides, antibodies that bind the peptides, compositions including the peptides and antibodies and methods of use of the peptides and antibodies. The interleukin-10 receptor-2 peptide consists of an 8-15 amino acid sequence that includes SEQ ID NO: 1 ((I/V)P(P/K/V/E)P(E/K/R/Q)N(A/V)R), SEQ ID NO: 2 ((S/L/V)PAF(A/P)(K/Q)(G/T/E)(N/T/D)), or SEQ ID NO: 3 (PP(G/T/Q/V)(V/T/A)(R/H/T/S)(GN/NHP/SAA)).
US10995135B2 Mycoplasma pneumoniae immunological detection method and kit
[Problem]An object of the present invention is to provide a detection marker that can simply and rapidly detect Mycoplasma pneumoniae, which is a pathogen of mycoplasma pneumonia, at a high sensitivity, a specific antibody against the marker, and also an immunological detection method and a kit containing the antibody.[Solution]Infection with Mycoplasma pneumoniae can be rapidly and specifically diagnosed by producing an antibody specifically reactive to P30 protein of Mycoplasma pneumoniae and performing an immunological assay using the P30 protein as a detection marker. The present invention enables easy and rapid detection of Mycoplasma pneumoniae and diagnosis of infection with the bacteria at a hospital or the like without need of specialized instruments or skilled techniques.
US10995133B2 Method for producing antibody
Disclosed is an antibody in which the 80th amino acid residue in a variable region based on the Kabat method and the 171th amino acid residue in a constant region based on the Kabat method are substituted with cysteine in an antibody in which the 80th amino acid residue in the variable region and the 171th amino acid residue in the constant region are not cysteine.
US10995131B2 Libraries of modified fibronectin type III tenth domain-containing polypeptides
The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure also provides various improvements relating to single domain binding polypeptides.
US10995130B2 Arginine-free TNFR:Fc-fusion polypeptide compositions and methods of use
Aspects of the invention are directed to arginine-free polypeptide-containing compositions and methods for treating disorders associated with inflammation or the autoimmune response. In particular, the polypeptide is etanercept.
US10995129B2 Non-standard insulin analogues
An insulin analogue comprises an insulin A-chain polypeptide and an insulin B-chain polypeptide. The A-chain polypeptide contains a Glu substitution at a position corresponding to position A8, and an Ala, Glu, Gln, His, Tyr, Phe or Trp substitution at a position A13, relative to wild type insulin. The B-chain polypeptide contains a cyclohexanylalanine substitution at position B24, relative to wild type insulin. The analogue may be an analogue of a mammalian insulin, such as human insulin. A nucleic acid encoding such an insulin analogue is also provided. A method of lowering the blood sugar of a patient comprises administering a physiologically effective amount of the insulin analogue or a physiologically acceptable salt thereof to a patient.
US10995127B2 Heterodimeric proteins and uses thereof
The present invention relates, inter alia, to compositions and methods, including heterodimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity.
US10995121B2 Human cytomegalovirus comprising exogenous antigens
Human cytomegalovirus vectors comprising heterologous antigens are disclosed. The vectors derived from the TR strain, are ganciclovir-sensitive, include active US2, US3, US6, US7 and UL131A genes, and have a deleterious or inactivating mutation in the UL82 gene preventing the expression of pp71.
US10995114B2 Scalable production of genetically engineered nanofibrous macroscopic materials via filtration
Provided herein are filtration-based purification methods for amyloid fibers, such as curli fibers, directly from microbial culture, and their fabrication into free-standing thin films. Additionally, methods for recycling amyloid fibers thing films by, for example, disassembly and re-assembly, are disclosed herein.
US10995112B2 Crystalline solvate forms of a pharmaceutical
Described herein are solid state 17α-ethynylandrost-5-ene-3β,7β,17β-triol including amorphous and crystalline forms and specific polymorphic forms thereof, and use of solid state 17α-ethynylandrost-5-ene-3β,7β,17β-triol in treating numerous diseases and disorders, including hyperglycemic conditions, such as type 2 diabetes and metabolic syndrome, autoimmune conditions, such as rheumatoid arthritis, ulcerative colitis and type 1 diabetes, among other inflammation related conditions, and neurodegenerative conditions in subjects or human patients.
US10995106B2 Composition containing organic silicon compound and paint and adhesive containing said composition
A composition according to the present invention contains 100 parts by mass of a component (A) and 1-200 parts by mass of a component (B) and is solid at 25° C., the solid form being achieved at 25° C. without spray drying, impregnation into wax, or the like, and said composition is useful as an additive for a paint composition and an adhesive composition. The component (A) is an organic silicon compound represented by general formula (1), and the component (B) is at least one of organic silicon compounds represented by general formulas (2) and (3) (R1 and R2 represent, independently of each other, an alky group having 1-10 carbon atoms or the like, R3 and R4 represent, independently of each other, a divalent hydrocarbon group having 1-20 carbon atoms, m represents an integer from 1 to 3, R5 represents an alkyl group having 1-10 carbon atoms or the like, and R6 represents a divalent hydrocarbon group having 1-20 carbon atoms; however, an oxygen atom, a sulfur atom, etc., may be interposed between the aforementioned R5 and R6 and/or between carbon-carbon bonds in R6, and a hydrogen atom in R6 may be substituted by a halogen atom or the like.)
US10995103B2 Substituted boric acid compound, pharmaceutical composition comprising same, and application thereof
A substituted boric acid compound, a pharmaceutical composition including the same, and an application thereof. The substituted boric acid compound is a compound represented by formula (I), or a crystal form, a pharmaceutically acceptable salt, a prodrug, a stereoisomer, a hydrate, or a solvent compound thereof. The boric acid compound has proteasome inhibitory activity, good pharmacodynamic/pharmacokinetic performance, good applicability, and high safety, and can be used for preparing drugs for treating diseases related to proteasomes.
US10995094B2 Temozolomide compounds, polymers prepared therefrom, and method of treating a disease
A temozolomide compound according to formula (I) is described, wherein R1, L1, and X are defined herein. The temozolomide compound can be used to prepare polymers comprising temozolomide. Additionally, the polymers comprising temozolomide can be particularly useful in the treatment of certain diseases.
US10995091B2 CXCR4 receptor antagonists
The compounds of formula (I) are antagonists of the CXCR4 receptor Wherein R1, X, Y and R2 are as defined in the claims.
US10995084B2 Pyrrolidine derivative
The present invention aims to provide a novel compound which has CGRP receptor antagonist activity and which is useful for the treatment of various diseases mediated by CGRP receptors. That is, the present invention relates to the pyrrolidine derivatives represented by the following formula (I) or a pharmaceutically acceptable salt thereof. In the formulae, W is ring, X is a carbon atom or the like, Y1 to Y4 are carbon atoms or the like, and R1 to R7 is alkyl or the like. The compounds of the present invention or a pharmaceutically acceptable salt thereof have an excellent CGRP receptor antagonist activity, and thus are useful as agents for the treatment of various diseases mediated by CGRP receptors.
US10995082B2 Cationic photoinitiator and preparation method and use thereof
This invention discloses a novel cationic photoinitiator and a preparation method and use thereof. The cationic photoinitiator has a structure as represented by general formula (I) below. It can match a longer absorption wavelength in the process of application and has an outstanding photosensitive property, and has characteristics of no proneness to migration and good yellowing resistance.
US10995081B2 Amide derivatives, process for preparation thereof and use thereof as insecticide
A compound represented by Formula (1): The compound can be used as insecticides.
US10995078B2 Compounds and compositions for inhibition of FASN
The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:
US10995077B2 Process to prepare higher ethylene amines and ethylene amine derivatives
The present invention relates to a process to prepare ethyleneamines of the formula NH2—(C2H4—NH—)pH wherein p is at least 2 wherein one or more units —NH—C2H4—NH— are present as a piperazine unit or precursors thereof wherein optionally one or more units —NH—C2H4—NH— are present as a cyclic ethylene urea unit or between two units —NH—C2H4—NH— a carbonyl moiety is present, by reacting an ethanolamine-functional compound, an amine-functional compound in the presence of a carbon oxide delivering agent, wherein at least one of the amine-functional compound or the ethanolamine-functional compound contains a piperazine unit, and the reaction is performed in a liquid that comprises water.
US10995073B2 PARG inhibitory compounds
The present invention relates to compounds of formula I that function as inhibitors of PARG (Poly ADP-ribose glycohydrolase) enzyme activity: wherein R1a, R1b, R1c, R1d, R1e, W, X1, X2, X3, X4, X5, X6, X7, c are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which PARG activity is implicated.
US10995071B2 Method for producing a polymorphic form of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide
This invention relates to a process for the preparation of Form B of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide. Also disclosed herein is Form B of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide, or pharmaceutical compositions thereof, obtainable by the process described herein.
US10995060B2 Amorphous Trisodium Sacubitril Valsartan and process for its preparation
The present invention provides for crystalline Form B1 of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenyl-methyl)-4-amino-2R-methyl butanoic acid ethyl ester sodium salt, crystalline Form B2 of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-2R-methyl butanoic acid ethyl ester sodium salt, a novel process for the preparation of crystalline Form B of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-2R-methyl butanoic acid ethyl ester sodium salt.
US10995058B2 Process for manufacturing hydroxyethyl ethylene amines
A process for preparing hydroxyethyl ethylene amines and/or ethylene urea derivatives thereof includes reacting monoethylene glycol with an amine-functional compound having at least two —NH— units, of which at least one is selected from the group of primary amine groups and cyclic secondary amine groups, in the presence of a carbon oxide-delivering agent. The amine-functional compound includes at least one —NH—CH2-CH2-NH— unit, wherein one or more —NH—CH2-CH2-NH— units in the amine-functional compound may be present in the form of piperazine moieties or ethylene urea moieties. The molar ratio of amine-functional compound to monoethylene glycol is in the range of 0.2:1 to 1.5:1 and the molar ratio of carbon oxide-delivering agent to —NH—CH2-CH2-NH— units in the amine-functional compound is at least 0.5:1. The process allows the conversion of monoethylene glycol into ethanol amines in the absence of metals-containing catalysts and without using ammonia.
US10995057B2 Method for hydrogenating nitriles in the presence of a ruthenium catalyst carried on ZrO2
The present invention relates to a process for hydrogenating nitriles with hydrogen in the presence of a ZrO2-supported ruthenium catalyst.
US10995053B1 Hydroxytyrosol ursolic acid ester with antioxidant activity and methods of preparing the same
A compound having the formula (I): is disclosed. Methods of preparing the compound of formula (I) are also disclosed. The compound of formula (I) can be prepared by reacting a compound of formula (II) with a compound of formula (III) in an organic solvent with EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide). The compound of formula (I) can also be prepared by reacting the compound of formula (II) with the compound of formula (III) in 1-ethyl-3-methylimidazolium hexafluorophosphate as a solvent with silicomolybdic acid as a catalyst.
US10995048B2 Natural 1,2-alkanediols, compositions having natural 1,2-alkanediols and processes for making the same
A process is incorporated herein for the synthesis of bio-1,2-alkanediols, comprising: providing a bio-alkene having a carbon chain of about 5 to about 20 carbon atoms and a bio-1-alkene regioselectivity of at least about 80%, at least about 92% and/or at least about 95%; and converting the bio-alkene to a bio-1,2-alkanediol having a carbon chain length of about 5 to about 20 carbon atoms. Methods for treating catalysts which may be incorporated in the process for the synthesis of bio-1,2-alkanediols are also included herein. Such bio-1,2-alkanediols are used in compositions and products alone as antimicrobial materials, or with existing bio-compounds and/or antimicrobials, preservatives, alternative preservation systems and/or hurdle technology components. The bio-1,2-alkanediols incorporate a natural and bio-based pathway for antimicrobial effects in various compositions such as cosmetic, pharmaceutical, industrial and household products.
US10995040B2 Ceramic matrix composite components having a deltoid region and methods for fabricating the same
A method for fabricating a ceramic matrix composite component having a deltoid region is provided. The method includes providing a porous ceramic preform. The porous ceramic preform includes a layer-to-layer weave of ceramic fibers that forms a modified layer-to-layer woven core and at least one 2-dimensional layer of ceramic fibers that is disposed adjacent to the modified layer-to-layer woven core. The porous ceramic preform is formed into a ceramic matrix composite body having the deltoid region such that the modified layer-to-layer woven core extends through the deltoid region.
US10995038B2 Method for manufacturing an acoustic attenuation panel made of an oxide ceramic-matrix composite material
A method for producing an acoustic attenuation panel from a composite material with a ceramic oxide matrix is provided that includes draping a plurality of plies having fibrous reinforcements including fibers of ceramic material in a mold to define a first skin, depositing blocks made of fugitive material on the first skin such that a space between two blocks is defined, and draping a second plurality of plies on a surface formed by the blocks such that a second skin is defined. Rounded corners of the blocks define radii for connecting the first and second skins with walls of a honeycomb core of the acoustic panel. The method further includes using a liquid medium to infiltrate the skins and spaces with a precursor of a ceramic phase, removing the liquid medium by evaporation or polymerization, and sintering to consolidate the ceramic oxide material and removal the fugitive material.
US10995033B2 System and method for improved portland cement basecoat plasters
Systems and methods according to present principles enhance aspects of applied plaster coats. In particular, the materials include a synthetic substitute aggregate (SSA), added to a cementitious base coat, for a plastering step prior to application of stucco or acrylic synthetic finishes or finish coats. The addition of SSA to a pre-blended cementitious base coat creates a light weight product which in some implementations is highly advantageous for the plastering industry.
US10995029B2 Method and apparatus for shaping glass sheets
The invention relates to a method for shaping a glass sheet comprising the steps (i) heating the glass sheet to a temperature suitable for shaping; (ii) depositing the glass sheet on a first bending tool for supporting the glass sheet thereon, the glass sheet being in a first position relative to the first bending tool; (iii) contacting an edge portion of the glass sheet such that the glass sheet is moved to a second position relative to the first bending tool; and (iv) shaping the glass sheet on the first bending tool. Positioning devices for moving a hot glass sheet during the method of the invention are described. A glass shaping line for carrying out the method is also described.
US10995021B2 System for oxidation of ammonia
The present disclosure relates generally to oxidation of ammonia using electrochemistry. Methods and systems may include at least one sensor to measure the concentration of ammonia in the effluent and/or the concentration of chlorine gas in the effluent. Methods and systems may also include at least one controller in communication with the sensor and/or the anode to reduce the current density of the anode generating the chlorine, and/or to change the flow rate of the ammonia containing water entering the reactor.
US10995015B2 System and method for purification of drinking water, ethanol and alcohol beverages of impurities
A system and method for the purification of beverage fluids, primarily alcohol beverages, based on the action of hydrodynamic cavitation processing of microbiological and chemical contaminants, micro particles and colloidal particles. The system is a batch system with a single vessel having an extraction tube and discharge tube extending into the same reservoir of fluid. Fluid is drawn through the extraction tube and forced through the discharge tube. The discharge tube contains cavitation elements dispersed along its length to generate hydrodynamic cavitation in the fluid as it is pumped through. The discharge fluid is mixed with the fluid already in the vessel and is re-drawn through the extraction tube in continuous batch processing.
US10995008B2 Process for the flash calcination of a zeolitic material
A process for the calcination of a zeolitic material, wherein the process contains the steps of (i) providing a zeolitic material containing YO2 and optionally further containing X2O3 in its framework structure in the form of a powder and/or of a suspension of the zeolitic material in a liquid, wherein Y stands for a tetravalent element and X stands for a trivalent element; (ii) atomization of the powder and/or of the suspension of the zeolitic material provided in (i) in a gas stream for obtaining an aerosol; and (iii) calcination of the aerosol obtained in (ii) for obtaining a calcined powder, a zeolitic material obtained by the above process, and its use as a molecular sieve, as an adsorbent, for ion-exchange, as a catalyst, and/or as a catalyst support.
US10995002B2 Large scale oxidized graphene production for industrial applications
Existing methods of producing high quality graphene/graphite oxides are generally accomplished by exfoliating graphite into flakes and oxidizing the graphite flakes with strong oxidizers under extreme conditions and require careful purification. The oxidizers are typically strong acids used in high concentrations at elevated temperatures requiring complicated purification processes to yield oxidized graphene/sheets. The existing processes can cost up to $12,000/gram. This invention uses a mild oxidant combined with mechanical processing where the sole products are oxidized graphite/graphene and water without the need for further purification.
US10995001B2 Graphene oxide percolation network
A percolation network of functionalised reduced graphene oxide flakes, the percolation network configured to allow for hopping of charge carriers between adjacent reduced graphene oxide flakes to enable a flow of charge carriers through the percolation network, and wherein the reduced graphene oxide flakes are functionalised to facilitate detectable changes in the flow of charge carriers in response to a stimulus to the percolation network.
US10994998B2 Setting of hardenable bone substitute
The invention relates to hardenable ceramic bone substitute compositions having improved setting, powders for such compositions and methods for their manufacture and use in medical treatment. More specifically the invention relates to hardenable bone substitute powder and hardenable bone substitute paste with improved setting properties, comprising calcium sulfate and heat-treated hydroxyapatite (passivated HA), which bone substitute is suitable for treatment of disorders of supportive tissue such as bone loss, bone fracture, bone trauma and osteomyelitis.
US10994995B2 Modified sulfur, method for preparing same, apparatus for preparing same, and use thereof
Disclosure relates to modified sulfur, preparation method thereof, preparation equipment thereof. The modified sulfur has spinnability or includes micro-structures such as fiber-, film- and network-like structure. The modified sulfur can be prepared by inducing polymerization with ultrasonic or ageing. The modified sulfur has various excellent features such as anticorrosiveness, waterproofing, strength, and fast drying and can control the features depending on its viscosity or polymerization degree. In addition due to the above features, the modified sulfur can be applied to anticorrosive or waterproofing material and can prepare anticorrosive or waterproofing material which has good workability, hardening, salt spray resistance, and weldability exceeding a certain level, and specially improved adhesiveness. Furthermore, when applying the modified sulfur to asphalt composition, gelation and depression are reduced, properties such as bending strength and tensile strength are improved, and it is possible to obtain asphalt composition with good working stability at RT.
US10994993B2 Method of forming enhanced super-resolution image
A method of forming an enhanced super-resolution image is provided. The method includes: preparing a substrate comprising a glass substrate, a metal layer on the glass substrate, and a biolayer on the metal layer; placing a biological specimen on the substrate, the biological specimen being in contact with the biolayer and being attached to the metal layer through the biolayer, in which the biological specimen is labeled by a plurality of spontaneous blinking elements therein; irradiating a light beam to the metal layer via the glass substrate; receiving fluorescence signals emitted from the spontaneous blinking elements within a time period; fitting a plurality of functions respectively to each of the fluorescence signals; pinpointing peak positions of the functions; and reconstructing the peak positions to derive the enhanced super-resolution image of an underlying structure of the biological specimen in proximity to the metal layer.
US10994992B2 Method and system for manipulating a cell
A method of manipulating a living cell is disclosed. The method comprises, directing a pulsed optical field to at least one conductive nanoparticle present in the vicinity of the cell, so as to generate cavitations at or near the conductive nanoparticle at sufficient amount to effect at least one cell modification selected from the group consisting of cell-damage and cell-fusion.
US10994988B2 Electronic system comprising a microelectromechanical system and a box encapsulating this microelectromechanical system
The present invention relates to an electronic system comprising an electronic system comprising an electromechanical microsystem and a hermetic box encapsulating said microsystem. The box includes a fastening plane. The electromechanical microsystem includes a sensitive part and at least two beams connecting the sensitive part to the fastening plane. The beams are thermally coupled to the sensitive part and are electrically coupled to one another. The system further includes a thermal regulator of the electromechanical microsystem including an electrical circuit including at least two ends connected to the beams, and a circuit controller able to generate an electrical current in the electrical circuit to modify the temperature of the sensitive part.
US10994987B2 Riding bracket
Horse-riding stirrup comprising a stirrup frame (2) which comprises a hooking portion (4) to a stirrup leather (100), a first side arm (6) and a support arm (8) connected to each other in an incident manner to define a frame compartment (10) engageable by a user's foot; a second side arm (12) comprising an articulation end (14) pivoted to the stirrup frame, and a free end (16) rotatable between a coupling configuration to the support arm and a release configuration therefrom in which the arm is spaced from the support arm to create a lateral disengagement opening (18) of the foot from the compartment. The second side arm comprises a flexible portion (20) which in the coupling configuration presses the free end in abutment with the support arm and which, in order to achieve the release configuration, allows the second side arm to bend in part to snap-disengage the free end from the support arm.
US10994982B1 Liquid saving device
A liquid saving device having a container, a lid for attaching to the container, the lid having a top side and a bottom side, a finger element attached to the lid, and a closure for covering the top side of the lid. The liquid saving device also having an inner cover for covering the bottom side of the lid.
US10994980B2 System for mixing and dispensing beverages
A drink vending apparatus is disclosed. A user provides user commands from a smart device to a control unit that comprises drink requests from the user. In response thereto, ingredients are dispensed from ingredient cartridges into a mixing container, and the mixed ingredients are dispensed from the mixing container into a receptacle.
US10994979B1 Portable beverage container systems and methods for adjusting the composition of a beverage
A beverage apparatus, the beverage apparatus being hand-holdable by a user of the beverage apparatus to be portable, can include a beverage chamber housing that includes a chamber for storing a consumable liquid. The beverage apparatus can include a dispensing assembly that includes a receptacle. The receptacle can retain a vessel. The vessel can include an electronic tag and can contain an additive. The dispensing assembly can be operatively controllable by a controller to output the additive from the vessel into the consumable liquid. The beverage apparatus can include one or more sensors, devices, or assemblies that can be used to detect a volume of liquid in the chamber or a liquid level in the chamber. The beverage apparatus can include an apparatus processing portion (ACP) and an apparatus database portion.
US10994976B2 Self-adjusting capping chuck for applying the closure elements on containers
A self-adjusting capping chuck includes a support having a longitudinal axis, a guide element fixed with respect to the support and having guides, jaws which engage respective guides and are movable with respect to the support between release and gripping positions, the jaws have respective gripping surfaces and first cam surfaces, and a control ring movable relative to the support along the longitudinal axis between lowered and raised positions and having second cam surfaces cooperating with first cam surfaces of the jaws, so that the movement of the control ring from the lowered to the raised position moves the jaws from the release to the gripping position. The control ring has an abutment wall arranged to abut on a head surface of a closure element so that, during movement of the chuck along the longitudinal axis, the closing element moves the control ring from the lowered to the raised position.
US10994975B2 Log lifter with improved leverage and adjustability
A lever device for lifting an object off the ground includes a lever member having a distal end that is positionable immediately adjacent a bottom end of the object. The lever device also includes a grip member that is operable with the lever member to lift the object off the ground. The grip member is adjustable relative to the lever member to accommodate a size of the object being lifted off the ground. The grip member includes a toothed or hooked end that grips an upper surface of the object to be lifted off the ground. The lever device further includes a handle that is graspable by a user to impart a lever force to the grip member and the lever member and thereby lift the object off the ground.
US10994974B2 Tower elevating assembly
A tower elevating assembly generally includes a platform assembly configured to move between a first elevation position and a second elevation position, a tower having a track assembly, wherein the track assembly includes first and second track portions, each being a single continuous structure, and a carriage assembly for providing support to the platform and moving within the track. A kit for a tower elevating assembly includes a platform assembly, a tower having a track assembly, and a carriage assembly configured for coupling with the platform assembly and the tower.
US10994969B2 Remote operated latch assembly and lifting hook with such an assembly
A lifting hook (14) provided with a remotely operated safety latch (12), wherein remote operation is used to both open and close the latch. The latch can be magnetically held (36) in the open position to connect and disconnect the load from the hook. Furthermore, an indicator (42) can be provided to indicate when the latch is latched and unlatched. The latch can be operated with lines with a first line (62) controlling one direction of movement of the latch and a second line (64) controlling a second direction of movement of the latch.
US10994963B2 Sheet post-processing device and image forming system including same
A sheet post-processing device includes: an alignment member which aligns a sheet bundle on a stacking tray; and a stapler which performs binding processing on a rear end of the sheet bundle. The stapler includes: a first stapler which moves along the rear end of a first sheet bundle and performs the binding processing on a plurality of positions at the rear end of the first sheet bundle; and a second stapler which performs, at one part of an end portion of the rear end on one side, binding processing different from the first stapler. The alignment member includes: a first alignment member and a second alignment member which align the sheet bundle in a first stacking position; and a third alignment member which is fixed to a position corresponding to the second stapler and which aligns the sheet bundle in a second stacking position with the first alignment member.
US10994960B2 Method for cyclically advancing material blanks in a packaging machine
A method for operating a packaging machine including one or more of the method steps advancing a transport chain along a chain deflection pulley, wherein chain clips are arranged on the transport chain and moved during the advancing motion of the transport chain along a run-on contour, to open at least one of the chain clips; introducing a flat material blank into the at least one open chain clip using a feed device or by entraining the flat material blank using a connection to a second material blank preceding the flat material blank, wherein the material blank enters the open chain clip during an advancing motion of the transport chain; closing the chain clip by leaving the run-on contour, to grip and secure the material blank in the chain clip; and transporting the material blank to a work station using the transport chain.
US10994955B2 Tray unit assembly
A tray unit assembly includes a housing, a separating/stacking unit, a tray unit and an elevating member. The separating/stacking unit includes a separating roller unit and a stacking roller unit provided in the housing. The tray unit is provided to be inserted into the housing and includes a first tray body fixed to the housing when the tray unit is inserted into the housing, and a second tray body connected to the first tray body to be slidable in a vertical direction and having a media stacking space formed therein. The elevating member is disposed to be movable up and down and configured to be in contact with a bottom surface of the second tray body to move the second tray body toward the stacking roller unit or the separating roller unit.
US10994954B2 Bulk material shipping container unloader
A bulk material shipping container unloader having an expandable supporter, a pallet receiver supported by the extendable supporter, a material director supported by the pallet receiver, and a bulk material container gate mover supported by the pallet receiver.
US10994953B2 Tray conveyor driven by brushless DC motor
A conveyor for conveying articles supported on independently powered and controllable trays. Each tray comprises a blade suspended from an article-supporting platform. A series of drive coils is embedded in the blade. A battery and a controller embedded in the tray drive the drive coils. The blade rides in a slot between two conveyor rails that support the tray platform. The slot is bounded by an array of permanent magnets along each rail. The drive coils produce an electromagnetic field that interacts with the permanent-magnet field in the slot to form a brushless dc motor that propels the tray along the rails.
US10994950B2 Automated guided vehicle with multistage loading structure
An automated guided vehicle with a multistage loading structure includes a vehicle body, and a loader in the vehicle body and operative to load articles in a multistage manner. The loader has a loading unit that is positioned between the articles loaded in the multistage manner and separately loads the articles. The loading unit moves up and down.
US10994946B2 Electromagnetic stopper for a cargo conveyor system
The present invention relates to an electromagnetic stopper for stopping and/or separating out cargo carriers and/or cargo conveyed on a continuously operated cargo conveyor system, comprising: a bistable solenoid having at least one coil and at least one permanent magnet; a cam, which can be retracted and extended with the aid of the solenoid, one or more electrical energy stores, in particular capacitors, a controller, which, with the aid of switches, discharges the energy store(s) via the at least one coil of the solenoid such that the cam is extended.
US10994945B2 Granular metering system
An additive feeder assembly includes a supply reservoir having an outlet and an outlet tube having a first end in fluid communication with the outlet and a second end located vertically higher than the supply reservoir. An air stream transports a first granular material discharged from the supply reservoir and into the first end of the outlet tube to the second end of the outlet tube. A granular material distributor is in fluid communication with the second end of the outlet tube. The granular material distributor has a top end configured for attachment to a feed supply for a second granular material, a central portion located vertically below the top end and configured to mix the first granular material and the second granular material, and a bottom end configured for vertically discharging the mixed first granular material and second granular material.
US10994941B1 Removable conveyor cartridge assemblies for mobile carrier units
Systems, methods, and computer-readable media are disclosed for removable conveyor cartridge assemblies for mobile carrier units. In one embodiment, an example removable assembly for a mobile carrier unit of a sortation system may include a frame, a conveyor belt disposed about the frame, a first sheet metal component coupled to a first side of the frame, the first sheet metal component including a first set of tabs extending from the first sheet metal component, and a tensioning device configured to tension the conveyor belt, the tensioning device having a first screw that engages a first tab of the first set of tabs.
US10994940B1 Apparatus for guiding containers for a conveyor
A container guide includes a guide rail and a single piece having a main body and retainers. At least one of the retainers is arranged in either a through passage or a recess in a surface-area portion of the main body. Each retainer includes a bent rail bar and a rail support. A portion of the rail support comprises a support arm that is perpendicular to a plane defined by the surface-area portion of the main body. The guide rail is arranged directly on the support arms for guiding the container.
US10994938B2 Vacuum processing device
The present invention provides a technique to enable sufficient space saving in a transit-type vacuum processing device. The vacuum processing device 1 of the present invention has: a vacuum chamber 2 where a single vacuum ambience is formed; first and second processing regions 4 and 5 that are provided in the vacuum chamber 2 and have a processing source that performs processing on a planar process surface of a substrate 10; and a conveyance drive member 33 that forms a conveyance path for conveying the substrate 10 so as to pass through the first and second processing regions 4 and 5. The conveyance path is formed as a single annular path when the conveyance path is projected onto a plane (vertical plane) containing: a normal line of an arbitrary point on a process surface of the substrate 10 conveyed through the conveyance path, and a trajectory line drawn by the arbitrary point on the process surface of the substrate 10 when the substrate 10 passes straight through the first and second processing regions 4 and 5.
US10994935B1 Large-span bulk material conveying system
Disclosed a large-span bulk material conveying system, including a folding arm conveyor and a dike-striding elevation-type feeding conveying device. The folding arm conveyor is mainly composed of an undercarriage mounted on the ground of a stockyard, a tower body mounted on the undercarriage and provided with a gyration apparatus and a hopper, a balance arm provided with a balance trolley, a conveying arm provided with a portal frame I, a portal frame II and an unloading trolley, a tower top and other main components, wherein the balance arm, the conveying arm and the tower top are mounted on the tower body. The folding arm conveyor can rotate horizontally, and the conveying arm can be folded and retracted by controlling the wire rope by the windlass, so that the folding arm conveyor can be prevented from colliding with other devices or buildings during the rotation.
US10994930B2 Replenishment and order fulfillment system
A warehousing system for storing and retrieving goods disposed in containers is provided. The system includes a multilevel storage array including an array of storage shelves for holding containers thereon, at least one substantially continuous lift for transporting containers to and from at least one level of the storage array, at least one transport vehicle located on the at least one level and configured to traverse a transport area transporting containers between the at least one continuous lift and container storage locations so that the at least one continuous lift communicates non-deterministically, via the transport vehicle, with storage locations of each of the storage shelves on the at least one level, an infeed transport system linked to the at least one continuous lift, and an order fulfillment station for generating order containers corresponding to customer orders where the order containers are entered onto the storage shelves of the storage array.
US10994929B2 Attachment system for refuse vehicle
An attachment for a vehicle includes an implement and a plate coupled to the implement. The plate has a top end, a bottom end, a right side, a left side, a first interface, and a second interface. The first interface includes (i) a first hook extending from the top end and positioned proximate the left side of the plate and (ii) a first aperture positioned proximate the bottom end and the left side of the plate. The second interface includes (i) a second hook extending from the top end and positioned proximate the right side of the plate and (ii) a second aperture positioned proximate the bottom end and the right side of the plate.
US10994925B2 Storage system for a shipping container
A shipping container storage system includes mounting posts that are mountable within the inner or outer channels along the corrugated side walls of a shipping container for supporting various load supporting accessories releasably along the mounting posts. A first mounting bracket configuration allows one or both ends of the mountings posts to be fastened to a perpendicular end surface at the top or bottom end of a channel receiving the mounting post therein. A second mounting bracket configuration includes a hook that allows the mounting posts to be suspended from a rigid anchor loop at a top end of a channel in the shipping container side wall.
US10994922B2 Metering valve mechanism of aerosol container and aerosol type product with said metering valve mechanism
An aerosol dispenser having a metering valve mechanism having a metering chamber and a propellant-accommodating space region configured to be isolated from each other by an annular piston, and a metering formation seal valve configured to isolate the metering chamber from a contents accommodation space region in a propelling mode. In a contents filling mode the seal valve is moved by the flow of the filled contents in a direction away from the stem to allow the filled contents to flow into the contents accommodation space region.
US10994918B1 Insulating device and method for forming insulating device
An insulating device can include an aperture having a waterproof closure which allows access to the chamber within the insulating device. The closure can help prevent any fluid leakage into and out of the insulating device if the insulating device is overturned or in any configuration other than upright. The closure may also prevent any fluid from permeating into the chamber if the insulating device is exposed to precipitation, other fluid, or submersed under water. This construction results in an insulating chamber that is substantially impervious to water and other liquids when the closure is sealed.
US10994906B2 Easy-to-remove cable tie
A cable tie having a locking head, a strap, and a truss projecting from the plane of the strap separated from the head by a slot. The strap may be passed over the truss, fed through the slot, and rested upon the truss to form a loop having a cavity therein. The strap may be subsequently passed around an object and fed into the head to lock the cable tie. A cutting implement may be inserted into the cavity to cut the loop and thereby release the cable tie from the object.
US10994898B2 Container assembly
A container assembly includes a first component, a second component, and a third component. Each component has an outer wall, a side wall extending upward from the outer wall, and a lip extending outward around a perimeter of the side wall. Each of the lips of the components are releasably lockable with another lip to form a modular container assembly.
US10994896B2 Slider bag with a detent
A storage bag includes a first sidewall and a second sidewall connected to the first sidewall so as to form an interior of the bag with an opening to the interior. The storage bag also includes at least one zipper profile provided adjacent to the opening to the interior of the bag. The at least one zipper profile has opposing closure elements that respectively interlock with each other. The storage bag also includes a slider with at least one opening member and at least one detent on at least one end of the bag. The at least one detent is configured to engage with the at least one opening member of the slider to provide a leak-proof end seal.
US10994894B2 Liquid storage tank protection system and method
A liquid storage tank has a breathing valve that vents the tank's headspace at a high-pressure value and admits an ambient gas at a low-pressure value. A controller generates a first control signal when the percentage of the catalyst gas is less than a catalyst threshold, a second control signal when the percentage of the catalyst gas exceeds the catalyst threshold, and a third control signal when the pressure in the headspace is equal to a low-pressure threshold between the breathing valve's low-pressure value and high-pressure value. The first valve is only opened to output inert gas at a discharge pressure greater than the breathing valve's high-pressure value in response to the second control signal. The second valve is only opened to output inert gas at a discharge pressure that is between the breathing valve's low-pressure value and high-pressure value in response to the third control signal.
US10994892B2 Food container and method of use
A versatile food container that uses a sealing layer to cover movable/reconfigurable/removable internal dividing compartments that maintains a leak-proof seal along the perimeter as well as in between the internal compartments. The container has a variety of features and accessories that can be applied, making it effective for storing, cooking and transporting food.
US10994890B2 Container system and apparatus
A container having a center portion and two side portions each situated at an angle to the center portion and extending in opposite directions such that the a left half of the container is substantially identical to a right half of the container. The container includes recesses and protrusions which enable the container to stack in two orientations generally perpendicular to each other.
US10994887B2 Rigid package for smoking articles
Package for smoking articles having: a group of smoking articles; an outer container having an open top end; a lid hinged to the outer container to close the open top end; a collar which is glued on the inside of the outer container so as to partially project outwards from the open top end and has a through pull-out opening, through which the smoking articles can be pulled out; and a sealing flap, which is glued to the collar, is arranged on the outside of the collar and on top of the collar itself, covers, at least when the lid is in the closed position, the pull-out opening, and is provided with a connecting tab which is permanently and non-removably glued to a front wall of the lid by means of a permanent glue so that the opening and closing of the lid also simultaneously opens and closes the pull-out opening.
US10994884B2 Portable film packing apparatus
A portable film packing apparatus includes a main body including a holding-and-drawing rod at the middle portion of the main body, a first combining rod is at a one end, and a second combining rod is disposed at the other end of the main body; a first roller unit having a first roller having its opposite ends respectively fixed with a pair of a first roller unit gears; and a second roller unit having second roller having its opposite ends respectively fixed with a pair of a second roller unit gears, wherein the first roller unit and the second roller unit are provided with the pair of the first roller unit gears and the pair of the second roller unit gears to mesh with each other, wherein a diameter of the first roller is smaller than a diameter of the second roller.
US10994881B2 Method for packaging a spectacle lens
Disclosed is a method for packaging an optical lens including two faces and a peripheral edge, at least one of the faces having a convexity marked by a peak point, the method including the following steps: a step of depositing a protective strip made from a rigid material at least partially along the edge, the width of the strip extending beyond the peak point of the convex face of the lens; a step of inserting the lens into an envelope delimited by a wall; a step of positioning the lens in the envelope, such that the protective strip acts as a spacer in order to maintain a distance between the wall of the envelope and the convex face of the lens and thus preventing any contact between the wall and the face.
US10994877B2 Web processing with at least one semi-rotary accumulator
Various apparatus embodiments include first, second, third and fourth shafts, and further include a first movable shaft having a first movable axis that is movable between a first axis position and a second axis position, and a second movable shaft having a second movable axis that is movable between a third axis position and fourth axis position. At least one linkage connects the first movable shaft to the second movable shaft. A motor linkage connects the at least one linkage to at least one motor for providing simultaneous movement of the first and second movable shafts.
US10994875B2 Device and method for transferring breast milk from an irregular shaped reservoir assembly for storage or feeding
A liquid milk transfer system for conveying milk from a milk reservoir device to a milk storage container. A support structure has a first opening that communicates with an interior of the milk storage container. The first opening of the support structure has an irregular circumferential shape partially the same as partial surface dimensions of the milk reservoir. The first opening receives and supports the milk storage container with a pouring spout positioned below the first opening, and the pouring spout located above the interior of the milk storage.
US10994871B2 Apparatus, system and method for fluid delivery
A filling aid device for filling a reservoir. The device includes a cover portion comprising a septum window; a slider beam comprising a septum cover; and a first filling aid tab attached to the slider beam, the first filling aid tab in slidable relation to the cover from a first position to a second position, wherein when the filling aid device is in an unlocked position, the septum cover is located below the septum window, wherein when the first filling aid tab is moved from the first position to the second position, the septum cover is moved from below the septum window, and the filling aid device is in the locked position.
US10994870B2 Device comprising a filling unit for filling containers with a product
The invention relates to a device comprising a filling unit for filling containers with a product. The invention furthermore relates to a system comprising such a device and to a harvesting machine provided with such a system. Lastly, the invention relates to a method for filling containers with a product by means of a filling unit.
US10994866B1 Flight test system for flapping-wing aerial vehicle
A flight test system for a flapping-wing aerial vehicle includes a host computer platform, a measurement mechanism, and a wind tunnel. The measurement mechanism is configured to mount a to-be-tested flapping-wing aerial vehicle prototype. The measurement mechanism includes an Euler angle controller, a flow angle controller, and a tripod. The flow angle controller is mounted on the tripod. The Euler angle controller is in transmission connection with the flow angle controller. The flapping-wing aerial vehicle prototype is detachably connected to the Euler angle controller by using a first connecting member. The host computer platform is in communication connection with the measurement mechanism and the wind tunnel, and is configured to control a wind speed of the wind tunnel and display a flight status of the flapping-wing aerial vehicle prototype in real time during test.
US10994860B2 Catalytic fuel tank inerting system
A fuel tank inerting system is disclosed. In addition to a fuel tank, the system includes a catalytic reactor with an inlet, an outlet, a reactive flow path between the inlet and the outlet, and a catalyst on the reactive flow path. The catalytic reactor is arranged to receive fuel from the fuel tank and air from an air source, and to react the fuel and air along the reactive flow path to generate an inert gas. The system also includes an inert gas flow path from the catalytic reactor to the fuel tank. The system also includes a non-uniform catalyst composition along the reactive flow path.
US10994855B2 Inductive interface for modular components
In some examples, an aircraft comprises a motorized module. The motorized module comprises a motor and a first coil. The motor is to operate equipment onboard the aircraft and generates vibrations during operation. The first coil is operable to wirelessly transmit power to a separate module onboard the aircraft based on electromagnetic induction between the first coil and a second coil in a separate module, and wirelessly transfer data with the separate module via the second coil based on the electromagnetic induction, the data being associated with the motor. A gap separates the motorized module and the separate module. The gap isolates the separate module from the vibrations.
US10994854B2 Aerodynamic aircraft wall comprising at least one vortex generator, and aircraft comprising the said aerodynamic wall
An aerodynamic aircraft wall has external and internal surfaces and is equipped with at least one vortex generator. The vortex generator has at least one active wall projecting with respect to the external surface of the aerodynamic wall. A connecting system connects the vortex generator to the aerodynamic wall. The connecting system includes at least one support having a base pressed firmly against the internal surface of the aerodynamic wall and a head which passes through the aerodynamic wall and collaborates with the active wall, at least one first fastener connecting the base of the support and the aerodynamic wall, at least one second fastener connecting the head of the support and the active wall.
US10994852B2 Door for a tiltrotor proprotor pylon
An embodiment of the present invention provides a blocking door that is pivotally disposed on a fixed nacelle of a tiltrotor aircraft for pivoting between a stowed position when a proprotor pylon is in the substantially horizontal position and a protective blocking position in front of the proprotor pylon when the proprotor pylon is positioned in the non-horizontal position. In other aspects, there is provided a blocking door and a method of reducing infrared and/or radar signatures of rotorcraft with a rotatable proprotor.
US10994850B2 Aspirators for evacuation assemblies
An aspirator includes a duct having a wall with a surface bounding a converging portion and a diverging portion of the duct. The converging portion of the duct has an inlet and the diverging portion of the duct has an outlet, the inlet being in fluid communication with the outlet through the converging portion and the diverging portion of the duct. The surface of the duct wall includes a conformal surface portion extending between the inlet of the duct and the outlet of the duct that is conformal with an aspirator seat surface portion of a support structure to conform the duct to the support structure. Evacuation assemblies are also described.
US10994848B2 Environmental control system for an aircraft
An environmental control system of an aircraft includes a compressing device having a compressor configured to receive a first flow of a medium and a turbine configured to receive the first flow of the medium and a distinct second flow of the medium. A dehumidification system is arranged in fluid communication with the turbine. A valve is configured to divert the second flow around the turbine and an inlet port is arranged in fluid communication with the compressor, the turbine, and the dehumidification system.
US10994846B2 Functional unit in a passenger cabin, including a support unit and a passenger seat system
A functional unit in a passenger cabin includes a support unit and a passenger seat system. The passenger seat system is formed in two parts and has an upper constructional unit and a lower constructional unit that are each separate components, the upper constructional unit arranged on the support unit and containing at least one backrest, and the lower constructional unit containing a seat frame, at least one seat element and restraint for the passenger on the seat. The seat frame is fastenable to seat rails on the floor of a passenger cabin. For the use position, the upper and lower constructional units are positioned such that a passenger seat is formed. In the use position, personal comfort for the individuals on the seats is not impaired as far as possible, and the division of the seat system into two parts cannot be seen by the user.
US10994845B2 Waste system pressure management system
A system for waste system pressure management is disclosed. In one or more embodiments, the system includes an electronically controlled valve and a controller communicatively coupled to the electronically controlled valve. The electronically controlled valve is coupled to a suction path of an aircraft waste system. The controller is configured to determine a pressure differential between an aircraft cabin and a vacuum source for the suction path. The controller is further configured to generate one or more signals to actuate the electronically controlled valve from a first position to a second position to regulate a pressure in the suction path when the pressure differential between the aircraft cabin and the vacuum source exceeds a threshold pressure differential. In embodiments, the electronically controlled valve is configured to allow more airflow through the electronically controlled valve in the second position than in the first position.
US10994843B2 Aircraft cargo pallet lock assemblies
Aircraft cargo lock assemblies are capable of positionally restraining movement of a cargo load pallet in both vertical and horizontal planes relative to the cargo deck of the aircraft. According to certain embodiments, the lock assemblies will include an actuator case and a restraint element which comprises at least one restraint plate and restraint detent, the restraint element being connected to the actuator case for pivotal movements between locked and released conditions relative to an edge of a cargo load pallet positioned on a cargo deck of an aircraft so as to positionally restrain the cargo load pallet against movement in both vertical and horizontal planes relative to the cargo deck. An actuator assembly is operably connected to the restraint element for moving the restraint element between the locked and released conditions thereof.
US10994839B2 System and method for rotating a rotor of a tiltrotor aircraft
A tiltrotor aircraft includes a rotor system, a pylon coupled to the rotor system, a spindle coupled to the pylon, an actuator arm coupled to the spindle, and an actuator. The actuator can cause the actuator arm to rotate, thereby causing the spindle to rotate the pylon and the rotor system. The actuator is in front of a forward spar of the wing of the tiltrotor aircraft and the actuator arm is about one-half (0.5) of an inch to about five (5) inches from the wing.
US10994835B2 Inertia weight assemblies for rotorcraft
An inertia weight assembly positionable within a receiving portion of a rotor blade for use on a rotorcraft. The inertia weight assembly includes a weighted core and a casing having a closed outboard end and forming a cavity. The weighted core is disposed in the cavity such that the casing at least partially encloses the weighted core. The weighted core is formed from a first material and the casing is formed from a second material that is dissimilar to the first material. The casing provides an interface between the weighted core and the receiving portion of the rotor blade. The second material is more bondable to the receiving portion of the rotor blade than the first material.
US10994832B2 Riblet film for reducing the air resistance of aircraft
A riblet film for reducing the air resistance of aircraft, comprising a suspension with magnetic particles enclosed therein. Depending on the pattern of a magnetic field acting on the riblet film, the magnetic field that is acting can be made visible, at least in certain regions, by changing the orientation of the magnetic particles. The riblet film allows an inspection of the aircraft structure located under the riblet film through the riblet film.
US10994829B2 Foldable rotor assembly for fixed-wing VTOL aircraft
A rotor assembly for a fixed-wing VTOL aircraft. The rotor assembly is configured to provide vertical flight for the fixed-wing VTOL aircraft. In one embodiment, the rotor assembly includes a hub assembly, a first rotor blade affixed to the hub assembly, and a second rotor blade affixed to the hub assembly. The hub assembly orients the second rotor blade in relation to the first rotor blade about an axis of rotation of the hub assembly with the first rotor blade and the second rotor blade vertically stacked when the hub assembly is stopped for wing-borne flight.
US10994828B2 Hinged rotor blade to provide passive variable pitch
A hinged propeller comprising a hub and one or more blades is disclosed. In various embodiments, a blade is connected to the hub via a hinge, wherein at least a substantial part of the blade has a longitudinal axis that is substantially parallel to a line extending radially from a center of the hub, and wherein the hinge has an axis of hinge rotation that is oriented at a non-zero acute angle to a line that is perpendicular, in a plane of rotation of the hub, to said longitudinal axis.
US10994823B2 Beaded panels and method of forming beaded panels
Beaded panels and method of forming beaded panels. A beaded panel as described herein includes a base structure comprising a sheet of material, and beads that comprise a protrusion on a first side of the base structure, and a concavity on an opposing second side of the base structure. A geometry of the beads comprises a center section having a conic shape about a longitudinal axis, flared sections symmetric about the center section along the longitudinal axis, and a transition section that curves outward from a base of the center section and the flared sections to blend with a flat surface on the first side of the base structure.
US10994815B2 Self-balancing surfboard
A board can have an upward-facing side arranged to enable a person to stand on the board while surfing. A motor can be attached to a downward-facing side of the board to propel the board. A computer system can use data from sensors and a steering system to actively respond to actions from the person riding on the board.
US10994811B1 Power pole actuator mount
A power pole actuator having a frame, the frame having at least one top plate and at least one opening. The power pole actuator further has a button coupled to the at least one opening, the button electrically coupled to a power pole controller such that when the button is depressed, a power pole moves upward or downward.
US10994810B1 Collapsible rail systems for marine vessels
A rail system for a marine vessel having an upper deck. The rail system has a set of forward rails that encloses a portion of the upper deck, where the set of forward rails includes a front rail and folding side rails. The set of forward rails is pivotable between an up position and a down position. A plurality of floor hinges pivotally couple the folding side rails to the upper deck. The set of forward rails has an up height when in the up position and a down height when in the down position that is lower than the up height.
US10994807B2 Transom mounted bracket for a fluid hinge trim tab system
A transom mounted fluid hinge bracket having one mounting plate that is connected at a lower distal end to a horizontal bracket portion which extends forward and aft of the transom of a watercraft in a bow to stern axial displacement, the horizontal bracket abutting the underside of the hull of a watercraft sitting flush with the underside of the watercraft, at least one fluid hinge receiver secured to the back side of the horizontal bracket portion on which the back of the substantially planar surface of the trim tab may rest, the at least one fluid hinge receiver containing the substantially planar surface in a position of the planar surface resting about parallel to the hull of the watercraft, and the at least one fluid hinge receiver without any load from the planar surface except at rest keeping the planar surface from descending below a horizon parallel to that of a horizon of the hull.
US10994806B2 Ultra-fast trimaran naval ship
An ultra-fast trimaran deep water and littoral naval ship suited to combat, search and rescue, and/or deployment operations has a plurality of semi-planing hulls connected to the underside of a deck in a trimaran configuration. Further, a plurality of propulsion stages including a cruise propulsion stage, a wind assisted propulsion stage, and a vectored direct thrust propulsion stage may be independently operated alone or in conjunction to propel the ship at various speeds suited to different situations.
US10994805B2 Human-powered vehicle control device
A human-powered vehicle control device includes an electronic controller that controls a motor. The motor assists in propulsion of a human-powered vehicle including a transmission configured to change, in steps, a first ratio of a rotational speed of a drive wheel to a rotational speed of a rotary body to which human drive force is input. The controller controls the motor in a first control state if the first ratio is changed by only one step during a predetermined period or a signal is received for changing the first ratio by one step during the predetermined period. The controller controls the motor in a second control state that differs from the first control state if the first ratio is changed by at least two steps during the predetermined period or a signal is received for changing the first ratio by at least two steps during the predetermined period.
US10994803B2 Bicycle sprocket
A bicycle sprocket has a rotational center axis. The bicycle sprocket comprises a sprocket body and sprocket teeth. The sprocket teeth include at least one first tooth and at least one second tooth. The at least one first has a first radial-tooth height. The at least one second tooth is adjacent to the first tooth and disposed on a downstream side in a rotational driving direction of the bicycle sprocket. The at least one second tooth has a second radial-tooth height. The first radial-tooth height is greater than the second radial-tooth height. The at least one first tooth includes a tooth tip having an axial center plane in an axial direction. The axial center plane of the tooth tip is offset from the axial center plane of the sprocket body in the axial direction.
US10994802B2 Bicycle transmission device
A bicycle transmission device basically includes an input rotational shaft, an output part, a transmission mechanism and a switching mechanism. The transmission mechanism includes a first rotating body configured to transmit rotation of the input rotational shaft and a fourth rotating body configured to transmit the rotation of the input rotational shaft. The switching mechanism is configured to selectively switch between a first state in which a ratio of a rotational speed of the output part to a rotational speed of the input rotational shaft is a first ratio and a second state in which the ratio is a second ratio that is different from the first ratio. The switching mechanism includes a one-way clutch and a switching unit.
US10994798B2 Operating device and base member
An operating device comprises a base member, an operating member, a user operating portion, and a restriction member. The base member includes a first end portion, a second end portion, and a grip portion. The first end portion is configured to be coupled to a handlebar. The second end portion is opposite to the first end portion. The grip portion is provided between the first end portion and the second end portion. The operating member is pivotally coupled to the base member about a pivot axis. The user operating portion is configured to receive a user input and provided at the second end portion of the base member. The restriction member is at least partly provided, as viewed along the pivot axis, between the user operating portion and the first end portion of the base member to restrict unintentional access to the user operating portion.
US10994794B2 Power distribution through undercarriage idler wheels
An undercarriage assembly for a tracked vehicle with a prime mover that provides a torque to the tracked vehicle, a final drive sprocket configured to provide a final drive torque on a track, a transmission mechanically coupled to the prime mover and the final drive sprocket to selectively transfer at least some of the torque generated by the prime mover to the final drive sprocket, at least one idler wheel that contacts the track, and an electric motor that provides an idler torque to the at least one idler wheel. Wherein, torque is distributed to the track through both the final drive sprocket and the idler wheel.
US10994793B2 Safety chain tie down mechanism for under bed hitch mounting system
A tie down apparatus that may be utilized for securing an item, such as a safety chain, wherein the tie down apparatus may be used with a hitch mounting system. In one embodiment, the tie down apparatus may include a receiving member, a tie down member, and a locking member. The receiving member may include an opening located there through. The tie down member may include at least one aperture, wherein the locking member may extend therethrough. The locking member may selectively engage the receiving member. The locking member may include a head that engages with a safety chain member positioned on the tie down apparatus to prevent disengagement between the locking member and the receiving member.
US10994791B2 Aerodynamic trailer system with dual stiffness skirt
An aerodynamic trailer system is provided that has a skirt support member with a trailer attachment that attaches the skirt support member to a trailer. The skirt support member has a skirt attachment that attaches the skirt support member to a skirt. The skirt has a height that extends in a vertical direction of the aerodynamic trailer system. The skirt has an upper side, a lower side, a front side, and a rear side. The skirt also has a lower section that extends in the vertical direction from the lower side to an attachment location with the skirt attachment. The skirt has an upper section that extends in the vertical direction from the attachment location to the upper side. The lower section has a higher bending stiffness than the upper section.
US10994790B2 Tubular component with an extruded profile
The disclosure relates to a tubular component for a chassis of a vehicle, wherein the tubular component may include an extruded profile made of an aluminum alloy. The extruded profile may include a rounded extruded profile base and profile walls extending from the rounded extruded profile base and facing one another, wherein the profile walls are curved towards one another to form the tubular component.
US10994789B2 Rear cross member structure for vehicle
The rear cross member structure includes a cam bolt seating unit formed in a rear cross member and having a cam bolt which fixes a lower arm and is seated in the cam bolt seating unit, a cam bolt insertion hole unit formed in the cam bolt seating unit and having the cam bolt inserted into the cam bolt insertion hole unit, and a cam bolt guide unit protruding from the cam bolt seating unit and configured to guide a rotation of the cam bolt by being brought into contact with sides of the cam bolt.
US10994788B2 Vehicle bottom structure
A vehicle bottom structure includes: side members; a plurality of cross members that extend in the width direction of the vehicle, are joined to the side members at both end parts, and support the bottom of a battery pack disposed under a floor panel between the side members, from below; and front-rear direction reinforcing members that extend in the front-rear direction of the vehicle and are joined on the cross members so as to cross the cross members.
US10994783B2 Metal part with controlled deformation orientation
A metal piece having at least two areas of lower mechanical strength than the body of the piece, said pieces being respectively arranged on one side and the other of a longitudinal central section (PM) of said piece and alternatively located in two locations separated longitudinally along the piece, the areas of lower mechanical strength than the body of the piece being formed by local control of the stamping temperature during a stamping process of the piece, notably a process comprising steps including heating the piece to a temperature range suitable for obtaining an austenitic stage, then stamping this piece in a stamping tool suitable for defining different temperatures in the different areas of the stamped piece, for example by virtue of the voids formed in the stamping tool or by local reheating of the stamping tool.
US10994779B2 Tow behind steerable caddy trailer
A steerable caddy trailer is provided that has an improved structure including a main frame assembly, spindle assemblies attached to each end of the main frame for attachment of a wheel, a pair of swinging arms forwardly extending from the main frame and pivotally attached to the main frame, and tie rods connecting the swinging arms with the spindle assembly such that pivoting of the swinging arms steers the wheel.
US10994777B2 Wheel steering apparatus to generate positive ackermann
Vehicle suspension systems are described herein. An example apparatus includes a cam pivotably coupled to a rear axle. The example apparatus also includes a first tie rod having a first end pivotably coupled to the cam and a second end pivotably coupled to a steering knuckle. The example apparatus also includes a second tie rod having a first end pivotably coupled to the cam outboard relative to the first end of the first tie rod and a second end coupled to a steering actuator.
US10994767B2 Steering column assembly
A steering column assembly having a vehicle-fixed mounting element and a sleeve element received in the mounting element, which is mounted displaceably in the axial direction in the mounting element for adjusting the steering column assembly. The steering column assembly further comprises an energy absorption device which can be firmly coupled to the mounting element and is firmly connected to the sleeve element, the energy absorption device being deformed in the event of a vehicle crash in consequence of a longitudinal displacement of the sleeve element, and at the same time absorbing part of the kinetic energy of the sleeve element during the event.
US10994766B2 Steering system
A steering system that is telescopically extendable and retractable using a motor driving force includes a motor, a telescopic steering shaft, a tube that supports the steering shaft such that the steering shaft is rotatable and that is movable with telescopic movement of the steering shaft, and a driving force transmission device that transmits a rotational driving force of the motor to the tube. The driving force transmission device includes a driving force converter that converts the rotational driving force of the motor to a linear driving force, and a coupling member that couples the driving force converter to the tube. The coupling member is breakable by an impact force applied thereto through the steering shaft and the supporting member during a secondary collision so as to decouple the driving force converter from the tube.
US10994757B2 Method and apparatus for gauge-face lubrication
A gauge-face lubrication assembly and related methods of use in which a removable and replaceable applicator member is positioned proximate a gauge-face for lubrication of a rail member. Generally, the replaceable applicator member can be molded of a resilient polymeric material having shaped-memory properties. The replaceable applicator member includes one or more molded lubricant channels for delivering lubricant supplied by a lubrication system to the gauge-face. Each molded lubricant channel can include a molded seal for sealably engaging a lubrication bracket that retains the applicator member in position against the gauge-face. The removable applicator member can further include a liner for physically engaging the gauge-face and protecting removable applicator member. The applicator member can include a coupling portion that insertably interfaces with a bracket channel defined in the lubrication bracket, whereby the applicator member can be removed and replaced in the event of damage or wear.
US10994754B2 Coupler for a railway vehicle, cores and method for production
A coupler having a support provided through the body of the coupler and a plurality of openings in the coupler which are configured as open cavities. The coupler structure includes a shank that has a vertical support as well as lateral support. The coupler may be configured with a double I-beam structure with openings into the shank. Cores that may be fixed to the mold may be used to form the coupler and produce the openings in the shank.
US10994753B2 Rail vehicle having guide device
The rail vehicle has a guide device configured to guide traveling of a bogie on a traveling track by rolling guide wheels in a state of bringing the guide wheels into contact with guide rails installed on both sides of the traveling track in a vehicle width direction perpendicular to a traveling direction, wherein: the guide device has an arm and the guide wheels, the arm having a central portion fixed to a stationary member, extending to both sides in the vehicle width direction, and having both end portions elastically deformable in a direction in which the guide rails extend, the guide wheels being mounted on the arm at the both end portions of the arm in the vehicle width direction; and a center of each of the guide wheels is displaced from a center line of the arm, the center line extending in the vehicle width direction.
US10994751B2 Railway traction vehicle with roof joint element
A railway traction vehicle, in particular a locomotive, is provided for pulling at least one coupleable railway car, which may be a two-level car, having a car body with a car roof which defines a car height. The locomotive includes a vehicle body with a vehicle roof which defines a vehicle height. If the vehicle height is lower than the car height, a roof transition element is disposed on a rear-side end region of the vehicle body. Since the cross-sectional profile of the roof transition element expands from the front edge, which follows a contour line of the vehicle roof, to the rear edge, which follows a contour line of the car roof, the flow resistance in the transition region from the locomotive to the subsequent two-level car is reduced in a simple way, so that traction energy losses and vehicle noise can be reduced.
US10994748B2 Transportation network infrastructure for autonomous vehicle decision making
According to some implementations of the present disclosure, a method for controlling an autonomous vehicle is disclosed. The method includes traversing the transportation network in accordance with a route and receiving vehicle sensor data from one or more vehicle sensors of the autonomous vehicle. The method also includes determining that the autonomous vehicle has encountered an occlusion scenario based on the vehicle sensor data. In response to determining that the autonomous vehicle has encountered the occlusion scenario, the method includes transmitting a request for infrastructure data to an external resource via a communication network, receiving infrastructure data from the external resource, determining a control action for the autonomous vehicle to perform based on the infrastructure data and the vehicle sensor data, and controlling the autonomous vehicle based on the control action.
US10994746B2 Vehicle dynamic control monitoring system
A vehicle dynamic control monitoring system includes a vehicle, a warning indicator, at least one vehicle dynamic control system (VDC), a tire pressure sensor and an electronic controller. The vehicle has a plurality of wheels rotatably mounted to the vehicle. The warning indicator is installed to the vehicle at a location visible to a vehicle operator. The at least one VDC and the tire pressure sensor are installed to the vehicle. The electronic controller is connected to the warning indicator, the at least one VDC and the tire pressure sensor. The electronic controller is configured such that in response to determining that at least one of the wheels has a tire pressure that is below a predetermined tire pressure range, the warning indicator is displayed indicating that the at least one VDC will operate with reduced effectiveness.
US10994743B2 Control method and system for vehicle
A control method for a vehicle is disclosed. The vehicle includes an in-vehicle controller, the in-vehicle controller pre-stores an instruction relationship, and the instruction relationship is used to represent an execution selection that is made by the in-vehicle controller from contrary instructions of at least two controllers. The method includes: receiving, by the in-vehicle controller, a first instruction and a second instruction (S410); and determining, by the in-vehicle controller, a vehicle control instruction according to the instruction relationship, the first instruction, and the second instruction (S420).
US10994735B2 Vehicle control device
In a case where a host vehicle that is traveling on a first lane intends to turn right or left at an intersection via a second lane whose traveling direction coincides with that of the first lane, a vehicle controller constituting a part of a vehicle control device performs a travel control or an assistance control that differs depending on whether the second lane is a priority lane where another vehicle that is different in type from the host vehicle preferentially travels.
US10994734B2 Methods and system for controlling launch of a vehicle having an automatic transmission
Systems and methods for operating a driveline of a vehicle that includes an automatic transmission and a torque converter are described. In one example, vehicle launch is controlled according to a linear quadratic regulator that provides feedback control according to torque converter slip error and vehicle speed error. The vehicle launch is also controlled according to feed forward control that is based on requested torque converter slip and requested vehicle speed.
US10994730B2 Traveling assistance method and traveling assistance device
A traveling assistance method detects another vehicle and objects around a host vehicle, sets a blind spot area from the other vehicle, specifies an object present in the blind spot area among the detected objects, and predicts an action that the other vehicle takes in accordance with the specified object.
US10994729B2 System and method for controlling lateral motion of vehicle
A control system uses a set of regions of states of lateral dynamic of the vehicle corresponding to a set of equilibrium points to control a vehicle. Each region defines a control invariant set of the states of the lateral dynamic determined such that the vehicle having a state within a region is capable to maintain its states within the region. Each region includes a corresponding equilibrium point and intersects with at least one adjacent region. The control system identifies collision-free regions at different time steps of control to produce a collision free sequence of regions forming a union of regions in space and time connecting a region including an initial displacement with a region including a target displacement. The control system produces a trajectory within the union connecting the initial displacement with the target displacement and control the vehicle according to the trajectory.
US10994726B2 Vehicle control system
An ECU (10) is configured to: detect a preceding vehicle (3) ahead of the vehicle (1), and set a speed distribution zone (40) defining a distribution of an allowable upper limit (Vlim) of a relative speed of the vehicle (1) with respect to the preceding vehicle (3) in a region around the preceding vehicle (3); and, execute traveling control of preventing the relative speed of the vehicle (1) with respect to the preceding vehicle (3) from exceeding the allowable upper limit (Vlim) in the speed distribution zone (40), wherein the speed distribution zone (40) includes: an allowable upper limit-zero zone (44) where the allowable upper limit becomes zero; and an entry prohibition zone (42) where entry of the vehicle (1) thereinto is prohibited.
US10994725B2 Four-wheel-drive vehicle
A four-wheel-drive vehicle including a powertrain operable to adjust a front- and rear-wheel driving force ratio that is a ratio between a driving force of front wheels and a driving force of rear wheels includes a control device that controls the powertrain and adjusts the front- and rear-wheel driving force ratio so as to reduce the driving force of the front wheels that are steered wheels, when it is detected that emergency avoidance to avoid collision with an avoidance target ahead in a traveling direction is necessary.
US10994723B2 Parking control device, parking control method, vehicle, and computer readable non-transitory recording medium storing a program
A parking control device includes a detection unit configured to detect at least one possible parking position in which a vehicle is capable of being parked, and a control unit configured to, after a target parking position has been selected from among the possible parking positions, initiate movement of the vehicle into the target parking position on the basis of an operation over a prolonged time period having been performed by a user, the operation over the prolonged time period being an operation in which an operation input unit is continuously maintained in a predetermined state over a threshold time period or greater, the operation input unit being used at least when switching between forward movement and rearward movement of the vehicle.
US10994722B2 Techniques for monitoring powertrain propulsive torque in battery electric and plug-in hybrid electric vehicles
Systems and methods for monitoring electrified vehicle powertrain propulsive torque and taking remedial action when needed involve continuously monitoring an error between the actual and requested propulsive torques and comparing the error to various threshold values. Error exceeding a particular threshold could be indicative of a malfunction, and the vehicle could be afforded an opportunity to regain equilibrium by temporarily decreasing torque output. When the error continues to exceed the threshold or another threshold, however, further remedial action could be required, such as shutting down the vehicle.
US10994719B2 Method and device for controlling hybrid vehicle
A method of controlling the hybrid vehicle in which electric power of the battery and electric power generated by an electric generator are supplied to a drive device, a running load of the drive motor is estimated on the basis of the driver's requirement, and a first distance to empty that allows for running in a state where the estimated running load is fulfilled is calculated on the basis of an amount of charge remaining in the battery and an amount of fuel remaining used to drive the fuel cell. Then, a required running distance is estimated on the basis of the driver's requirement, and, on the basis of the first distance to empty and the required running distance, a necessary energy replenishment operation is notified to the driver.
US10994718B2 Multi-master system, power controller and operating method of the multi-master system
A multi-master system includes a first master, a second master, and an integrated control circuit controlled by each of the first and second masters. The integrated control circuit includes a first dedicated block configured to provide a first function to the first master, a second dedicated block configured to provide a second function to the second master, and a global using block configured to provide a common function to each of the first and second masters.
US10994713B2 Brake traction control system for a vehicle, vehicle including same and method thereof
A brake traction control system for a vehicle a braking input member, a brake modulator and a controller. The braking input member can be manually actuated and controllable to manipulate the vehicle braking system by controlling the pressure. The brake modulator can be controllable to manipulate the vehicle braking system by controlling the pressure. The controller can be configured to control the brake modulator in an obstacle crawl control mode such that the controller controls the brake modulator to adjust the pressure. The controller can perform processing in the obstacle control mode including: performing a first determination to determine whether the acceleration input member is actuated to control the power source assembly to propel the vehicle; performing a second determination to determine whether a speed of the vehicle satisfies predetermined criteria; and controlling the pressure based on the first determination and the second determination.
US10994712B2 Vehicle control device and vehicle control method
An environment information acquisition unit acquires an image in which environment around a vehicle has been imaged, information indicating a contact with the vehicle or an impact on the vehicle, surround sounds, approach identification information for enabling an approach of an emergency vehicle to be identified, and the like as surrounding environment information of the vehicle. A vehicle control processing unit recognizes predetermined external stimulation information included in the surrounding environment information, for example, a specific signal or a movement with a specific pattern, a contact to a specific part, and a specific sound. The vehicle control processing unit uses the recognized predetermined external stimulation information as a vehicle brake instruction from outside and starts a vehicle braking sequence to stop the vehicle. Even if an abnormality occurs in an automatically driven vehicle and the like, vehicle brake control is easily applied to a traveling vehicle from outside.
US10994711B2 Wireless towed vehicle breakaway detection and alert
Breakaway detection and alerting is described for the breakaway of a towed vehicle. In one example, a system includes a breakaway detector attached to a towed vehicle to detect when a distance to a tow vehicle has exceeded a predetermined distance and to generate a breakaway detection signal and a wireless interface coupled to the detector to receive the breakaway detection signal and to transmit a wireless breakaway alert signal in response thereto.
US10994707B2 Position and force sensor assembly for vehicle brake pedal
A vehicle pedal sensor assembly for use in a vehicle brake pedal including a base and a pedal arm pivotally mounted to the pedal base. A sensor housing includes a non-contacting pedal position sensor and a contacting pedal force sensor. The sensor housing is mounted to the base of the vehicle brake pedal. A magnet is mounted to the pedal arm. The pedal position sensor senses a change in the magnitude and/or direction of the magnetic field generated by the magnet in response to a change in the position of the pedal arm for determining the position of the pedal arm. A pedal force application member exerts a force against the pedal force sensor in response to the change in the position of the pedal arm for determining the position of the pedal arm. The force sensor may be a piezoelectric element, a load cell, or a strain gauge.
US10994704B2 Transport vehicle spray apparatus
A transport vehicle spray apparatus. The transport vehicle spray apparatus has at least one storage tank. A pump transports material from the storage tank through at least one filter and a manifold to at least one spray bar. The spray bar incorporates spray nozzles through which the material from the storage tank is dispensed. In one embodiment, the spray bar is connected to a collapsible frame on the top and back of the transport vehicle storage space. The collapsible frame can expand and collapse by sliding along the length of the walls of the transport vehicle storage space. As the frame expands and collapses, the spray bar coats the interior surfaces of the transport vehicle storage space with the material from the storage tank. The transport vehicle spray apparatus is utilized to spray and coat the walls of a transport vehicle's storage space with a desired fluid.
US10994702B2 Adapter for a wiper blade of a motor vehicle and assembly comprising such an adapter
The invention proposes an adapter (26) which is delimited by two external lateral faces and which is shaped so as to be mounted in a cap (28) of reverse U-shaped section, comprising a pair of front locking lugs (44a, 44b) which cooperate with the associated notches (59a, 59b) of the adapter (26) in order to fix the cap (28) to the adapter (26) in a dismantlable manner, each of the lateral faces (29a, 29b) of the body (25) of the adapter (26) comprising a front locking notch (59a, 59b), each thereof being capable of receiving an associated front locking lug (44a, 44b) of the cap (28), and the body (25) of the adapter (26) comprising rear locking notches which are arranged at one end of a resilient branch (62a, 62b) of the adapter.
US10994699B2 Card key for vehicle
A vehicle card key, includes: a mainboard part on which an electronic element for wireless transmitting/receiving with a vehicle is mounted; a connector part formed on the mainboard part; a housing part which covers the mainboard part avoiding the connector part; and a switchboard part which has at least one among a switch and light-emitting diode mounted thereon, and which is layered on the mainboard part and is connected to the connector part.
US10994698B2 Remote keyless entry system
A remote keyless entry system includes an in-vehicle device including an in-vehicle device controller, an in-vehicle device transmitter that transmits an in-vehicle device signal, and an in-vehicle device receiver that receives a portable device signal, and a portable device including a portable device controller, an acceleration sensor, a portable device receiver, and a portable device transmitter, wherein the portable device controller calculates a distance from the in-vehicle device to the portable device based on the in-vehicle device signal, calculates a first travel distance based on acceleration, and causes the portable device transmitter to transmit the portable device signal including at least the distance, the in-vehicle device controller receives the portable device signal multiple times and calculates a second travel distance based on distances included in received portable device signals, and whether a relay attack is performed is determined based on the first travel distance and the second travel distance.
US10994696B2 System and method determining seatbelt webbing payout
A seatbelt retractor includes a retractor frame, a spool fixed for common rotation with a spool shaft, a seatbelt webbing wrapped around the spool, a reduction mechanism, and a sensor coupled to the reduction mechanism for sensing the movement of the spool.
US10994693B2 Airbag and airbag assembly
An airbag and an airbag assembly including a gas generator and an airbag. The airbag (10) forms a first end (11) and a second end (12), the first end (11) being a free end of the airbag, and the second end (12) being used for fixing the airbag to a mounting position. The airbag (10) forms a folding portion (13) and a rolling portion (14) in the collapsed stat. The folding portion (13) is formed by folding one part of the airbag in an “N” shape; the rolling portion (14) surrounds a periphery of the folding portion (13), so that the folding portion (13) is surrounded by an inner side of the rolling portion (14).
US10994691B2 Airbag
An airbag having an outer skin enclosing a gas space. The outer skin has a first side wall (11) and a second side wall (12). The first side wall (11) and second side wall (12) are connected to one another at a first end (71), the first side wall (11) extends from the first end (71) to a second end (72), the second side wall (12) extends from the first end (71) to a third end (73), a third side wall (23) extends from the second end (72) of the first side wall (11) to a fourth end (74), and a fourth side (24) wall extends from the fourth end (74) to the third end (73) of the second side wall (12). The third side wall (23) is separate from the first side wall (11) and extends from a fifth end (75) connected to at least a portion of the second end (72) of the first side wall (11) by a first seam (81). The fourth side wall (24) is separate from the second side wall (12) and extends from a sixth end (76) connected to at least a portion of the third end (73) of the second side wall (12) by a second seam (82).
US10994689B2 Retractable side protecting airbag for child safety seat
The present invention discloses a retractable side protecting airbag for a child safety seat which includes a side protecting base provided on an outer side surface of the seat body. Specifically, the side protecting base is provided with the retractable side protecting airbag. The retractable side protecting airbag is correspondingly provided with an air deflating hole. The side protecting airbag is internally provided with a resetting structure. An outer end of the retractable side protecting airbag is provided with a side protecting cover. The protecting cover and the side protecting base are locked to each other and work collaboratively for folding the retractable side protecting airbag. The present invention has a reasonable structure and a long distance for crumpling, and is capable of providing buffering and effective energy absorption, thereby greatly reducing the damage to children from side crashes.
US10994684B2 Airbag device for vehicle
An airbag device for a vehicle may include: a mounting housing having an airbag module mounted therein; one or more holders formed on the mounting housing; a steering wheel engaged to the holders; one or more mounting members slidably inserted into the engagement portion between the mounting housing and the steering wheel; and one or more hook members installed at positions spaced a predetermined distance apart from the center of the steering wheel, in order to fix the mounting member at a plurality of points.
US10994681B2 Bumper beam and vehicle
A bumper beam for a vehicle that is lightweight and high in strength is provided. A bumper beam for a vehicle includes a first member and a second member. The first member includes a first top panel part, two first vertical wall parts, and two first flange parts. The second member includes a second top panel part, two second vertical wall parts, and two second flange parts. The second top panel part includes a protruding part that protrudes toward a side opposite to the first top panel part. The two second vertical wall parts are disposed such that the second vertical wall parts respectively face close the first vertical wall parts inside the first member. The two second flange parts are disposed such that the second flange parts are connected to the two second vertical wall parts and joined to the first flange parts, respectively.
US10994679B2 Onboard electrical system for a motor vehicle and method for operating an onboard electrical system for a motor vehicle
An onboard electrical system for a motor vehicle is provided having a primary power supply network and a secondary power supply network electrically connected to the primary power supply network via a DC-DC converter, wherein the primary power supply network and the secondary power supply network are connected to one another via a blocking diode of the DC-DC converter and the blocking diode has a forward direction thereof oriented from the primary power supply network toward the secondary power supply network, and wherein an insulation monitoring device having a measuring resistor is associated with the secondary power supply network for determining an insulation fault. It is provided that an additional resistor is connected in parallel with the blocking diode for bridging thereof, such that an insulation fault common to the primary power supply network and the secondary power supply network can be determined by the insulation monitoring device. A related method for operating an onboard electrical system for a motor vehicle is also provided.
US10994678B2 Method and system for the automated testing of electrical cabin loads in a cabin of an aircraft
A method for the automated testing of electrical cabin loads in a cabin of an aircraft comprises activating at least one electrical cabin load in a predetermined operating mode via a test controller; recording an electric power consumption profile of the at least one electrical cabin load in the activated operating mode via a power controller of an electric power distribution system of the cabin of the aircraft, wherein the power controller regulates electric power consumption of the at least one electrical cabin load within the power distribution system; transmitting the recorded power consumption profile to the test controller; and comparing the recorded power consumption profile with a reference profile for the activated operating mode of the at least one cabin load via the test controller, in order to test the at least one electrical cabin load for operability.
US10994672B2 Tethered fastener apparatus and method
A tether fastening device for an automobile body structure includes a fastener clip, at least one tether strap, a tether clip bracket, a clip strap coupler, and a bracket strap coupler. The clip strap coupler operably couples to a slot in the automobile chassis. The tether clip bracket attaches to the fastener clip when in an attached position. The bracket strap coupler is attached to the body panel.The tether strap allows for controlled detachment between the clip strap coupler and the bracket strap coupler. The strap may include a mesh to absorb the deployment energy and decelerate the body panel in a controlled manner. In the event of an airbag activation, the tether clip bracket and the fastener clip initially accelerate and then decelerate from each other. The pair of tether straps control the deceleration and separation distance of the clip strap coupler and bracket strap coupler.
US10994671B2 Overhead console wire brackets for wire management
A vehicle includes a roof assembly including a roof panel. A headliner is located interior of the roof panel. An overhead console assembly is connected to the headliner. An overhead console wire bracket includes a longitudinal portion that extends in a vehicle longitudinal direction from the overhead console assembly toward a front edge of the headliner and a lateral portion that extends from the longitudinal portion in a vehicle lateral direction. The lateral portion engages a wire that extends over the front edge of the headliner.
US10994670B2 Console with grounded trim ring
A vehicle console includes a trim ring disposed over a periphery of a housing. The trim ring includes a polymeric material and is electrically conductive and grounded. A proximity switch assembly is retained in the housing. The proximity switch assembly includes a proximity sensor proximate a sensing pad for generating an activation field. The sensing pad is proximate the trim ring.
US10994665B2 Vehicle display system
Disclosed is a vehicle display system (1) for displaying an image of surroundings of a vehicle. The vehicle display system (1) includes: a display (18a) configured to display an image thereon; a camera (4, 6, 8, 10) mounted on the vehicle and configured to image surroundings of the vehicle; and a display control unit (20) configured to subject an image captured by the camera to mask processing, using a mask image (MR, MF) including a semi-transparent portion (M3, M4, M14, M16) corresponding to a vehicle body, and a portion (M8, M18, M19) corresponding to a window of the vehicle and having a transmittance lower than that of the portion corresponding to the vehicle body, to generate a masked image (D), and cause the masked image to be displayed on the display.
US10994663B2 Clamping jaw for a support assembly for a bicycle carrier
A jaw member for a support assembly for securing a bicycle to a load carrier for a vehicle. The jaw member includes a frame work structure formed by at least one support element and at least one rib. The frame work structure is adapted to enable the jaw member to withstand a relative high amount of tensile stress while still being relatively light weight.
US10994659B2 Rearview mirror assembly with antenna
A rearview mirror assembly includes a main housing defining an exterior surface, an interior, and an open side, the exterior surface having a recess therein. The assembly also includes a control module coupled within the interior of the housing, a mirror coupled over the open end of the housing, and a communication module. The communication module includes an antenna electrically coupled with the control module and an antenna housing at least partially enclosing the antenna and coupled within the recess of the exterior surface of the main housing.
US10994658B2 Vehicle display system
There is provided a vehicle display system to be used with a vehicle control unit which is configured to control a vehicle in an automated driving mode. The vehicle display system includes a display unit which is provided around or inside a license plate of the vehicle, and a display control unit which is configured to turn on the display unit while the vehicle control unit executes the automated driving mode.
US10994657B2 System and method for providing front-oriented visual information to vehicle driver
A camera system is installed on the front end of a vehicle, either on the left front, the right front, or both sides. The camera is linked via wired or wireless connection to an onboard computer and a navigation display that is located within the passenger compartment of the vehicle. The driver reviews a visual description on the display of any oncoming traffic in the form of motor vehicles, pedestrians, cyclists, animals and the like on the navigation display via a single screen, split screen or alternating screens. The camera system can include a speed sensor that detects when the vehicle reaches a threshold speed to activate or de-activate the camera. Alternatively, the computer can activate the system when a tum signal is activated, and de-activate the system when the tum signal is no longer activated. This camera system can be retrofitted into older vehicles.
US10994655B2 Electronic control unit and in-vehicle video system
An in-vehicle video system includes cameras that capture rear and side areas of a vehicle body, monitors that display video images captured by the cameras on screens thereof, and an ECU that shapes the video images that are displayed on the monitors. The cameras are accommodated in housings that are provided on left and right sides of a vehicle body, and side turn signal lamps are provided individually on external surfaces of the housings. The ECU controls a video image processing circuit so that the video images of the rear and side areas of the vehicle body are displayed on two portions of the screen of the monitor at different compression ratios and that the compression ratios change according to vehicle information.
US10994654B2 Rear pre-crash flashing hazard lamp system
A rear pre-crash safety system of a vehicle comprising a judgement logic adapted to issue at least one collision warning signal in response to a detected radar signal reflected by an object approaching the vehicle from behind depending on a radar cross section, RCS, of the approaching object and depending on a velocity of the approaching object relative to the respective vehicle.
US10994653B2 Vehicle proximity notification device, vehicle and vehicle proximity notification method
A vehicle proximity notification device for notifying a vehicle approach using a first speaker and a second speaker provided in the vehicle includes a sound source that outputs a signal that corresponds to a sound for notifying an approach of the vehicle and that is input to the first speaker and the second speaker; and an information processor that changes a phase of at least one signal out of a signal input to the first speaker and a signal input to the second speaker in accordance with a speed of the vehicle.
US10994651B2 Method and system for notifying an operator
A system that includes a notification light configured to be coupled with a first vehicle and to emit light to notify an approaching, second vehicle of the location of the first vehicle. A controller is provided that includes one or more processors configured to determine one or more of a direction of movement of the first vehicle, a speed of the movement of the first vehicle, or a distance between the first vehicle and the approaching, second vehicle. The controller is configured to notify the approaching, second vehicle of the one or more of the direction of the movement of the first vehicle, the speed of the movement of the first vehicle, or the distance between the first vehicle and the second vehicle by directing the notification light to change a characteristic of the light emitted by the notification light.
US10994641B2 Positioning device for vehicular seat
Disclosed is a positioning device for a vehicular seat that is configured to enable a driver or occupant to adjust a position of a headrest according to a body type or posture, so that the driver can drive a vehicle in a comfortable position, as well as minimizing an injury to cervical vertebrae in a car accident.
US10994640B2 Cover assembly for vehicle armrest
Arm support (12) for an armrest (10), comprising a frame (19) that comprises connectors for the fixed or moveable attachment to a structure, in particular to a structure of a vehicle, wherein the frame comprises longitudinal bars (23, 24) and cross bars (21, 22) that are connected to one another with connectors (25, 26, 27, 28).The particularity is that at least a first type of connector is provided that is connectable with at least one longitudinal bar (23, 24) selected from a set of longitudinal bars of different length, and/or with at least one cross bar (21, 22) selected from a set of cross bars of different length.
US10994639B2 Armrest device
Provided is an armrest device that can be positioned in an appropriate position suitable for the build of the vehicle occupant. The armrest device (10) comprises an interior member (1) provided on an inboard side of a vehicle door, and an armrest main body (9) supported by the interior member so as to be moveable between an initial position and a projecting position more inboard and forward than the initial position.
US10994637B2 Seat slider device
A seat slider device may include a lower rail attachable to a body of a vehicle; a belt arranged along a longitudinal direction of the lower rail and having both ends thereof fixed; and an upper rail attachable to a seat, slidably engaging with the lower rail, and including an actuator configured to feed the belt. The actuator may be configured to apply a drive force on a lower surface of the belt.
US10994636B2 Sliding device for a vehicle seat provided with an improved rail design
The present invention relates to a sliding device (100) for a vehicle seat, comprising a pair sliding tracks (10), each including a lower rail (20) and an upper rail (30), which allow to obtain an improved stability and to reduce the sliding efforts when the upper rails slide relative to the lower rails. Each upper rail is constrained to a respective lower rail and is free to slide relative thereto, balls (70) are arranged between said upper rail and said lower rail, and said upper and lower rails are shaped so as to define a lower and an upper ball guides (72, 74) on each side thereof. The design of said upper and lower rails at said lower and upper ball guides (72, 74) is such that efforts during relative sliding movements of the rails are reduced, while enhancing stability of the rails and preventing deformations thereof.
US10994634B2 Motor vehicle seat floor slide rail having a gap elimination structure
A motor vehicle seat floor slide rail includes a lower slide rail assembly (100), an upper slide rail assembly (200) and a gap elimination mechanism (230, 230′), with a shaft-provided gap elimination cam (231L, 231R), on an upper slide rail longitudinal end, having a rotation center (232a) axis perpendicular to an upper rail longitudinal direction. A locking window face (117L, 117R) has an aluminum slide rail (110) longitudinal gap elimination face (113L, 113R). A rail locked state has a cam face (2311L, 2311R) in contact with the gap elimination face to eliminate a Y and Z direction gap. In a rail unlocked state, a locking mechanism (240) drives the gap elimination cam, such that the cam face loses contact with the gap elimination face. The gap elimination cam moves in linkage with the locking mechanism, reducing sliding friction, and having the advantage of low sliding assistance motive power.
US10994630B2 Method and apparatus for controlling power consumption of vehicle and vehicle
The present disclosure proposes a method and apparatus for controlling power consumption of a vehicle, and a vehicle. The method comprises: determining state information of the vehicle according to driving data of the vehicle; and adjusting a power consumption mode of an energy consumption circuit in the vehicle according to the state information, wherein the energy consumption circuit consumes different amounts of energy in different power consumption modes.
US10994625B2 Energy display system, display device, and energy display method
An electric vehicle charging and discharging system according to the present invention includes: a charge and discharge unit capable of charging a battery mounted on an electric vehicle and discharging the battery; a first communication unit that acquires a vehicle identification number of the electric vehicle and a dischargeable capacity value indicating a dischargeable amount of power of the battery from the electric vehicle when the electric vehicle is connected with the charge and discharge unit; and a display unit that displays the vehicle identification number and the dischargeable capacity value acquired by the first communication unit.
US10994620B2 Electric bicycle and battery lift mechanism and battery carrying device thereof
An electric bicycle and a battery lift mechanism and a battery carrying device thereof are disclosed. The battery lift mechanism includes a bracket, a carrier for carrying a battery, an upward-force device coupling with the carrier, and a locking device selectively in an unlocked state or a locked state. The carrier is movable relative to the bracket along an up-down path; the upward-force device is capable of applying an upward force to the carrier. When the locking device is in the locked state, the locking device interferes with the battery to limit the relative movement between the battery and the bracket. When the locking device is in the unlocked state, the interference between the locking device and the battery is removed, so that the upward-force device drives the carrier carrying the battery to move upward relative to the bracket.
US10994618B2 Vehicle electrical system with inverter, energy store, electrical machine and ac transmission terminal
A vehicle electrical system is equipped with an inverter, an electrical energy store, an electrical machine and an AC transmission terminal. The inverter has a first and a second side and is configured to transmit power between these sides. The first side of the inverter is connected to the energy store via input current terminals of the inverter. The second side of the inverter is connected to the electrical machine via phase current terminals of the inverter. The inverter has at least two H-bridges. Each of the H-bridges bypasses the two sides of the inverter. The AC transmission terminal is connected to the second side of the inverter.
US10994617B2 Distributed battery thermal runaway detection
A system includes a primary monitoring system to determine a battery status of a battery pack and a secondary monitoring system configured to monitor the battery status as communicated by the primary monitoring system over a network. At least one of the primary and secondary monitoring systems generates a warning signal when the battery status comprises a thermal event that reaches a predetermined level.
US10994616B2 Movable body rescue system and movable body rescue method
Each vehicle includes a detection device configured to detect a situation outside the vehicle. When a server receives from a depleted EV a help signal requesting power supply from another vehicle to the depleted EV, the server selects, from among the other vehicles, a rescue EV to supply electric power to the depleted EV. The rescue EV moves to the depleted EV, determines a stopping position of the rescue EV from a situation around the depleted EV detected by the detection device, and performs power supply to the depleted EV at the stopping position.
US10994614B2 Pump system for vehicles
A vehicle-mounted pump system is disclosed for use with a service vehicle. A chassis can be configured to be secured to the service vehicle, and a frame can be supported by the chassis. A plurality of pumps can be supported by the frame, with each of the pumps being configured to pump liquid for dispersal external to the service vehicle. A power source can be supported by at least one of the chassis and the frame. A power transmission system can be configured to transfer power from the power source to the plurality of pumps.
US10994612B2 Agent system, agent control method, and storage medium
An agent system includes a microphone configured to collect a sound of a vehicle interior, a speaker configured to output a sound to the vehicle interior, a recognizer configured to recognize a meaning of the sound collected, an agent controller configured to generate an agent sound for speaking to an occupant of a vehicle on the basis of the meaning recognized and cause the agent sound to be output to the speaker so that a sound image of the generated agent sound is localized at a prescribed position, and a travel environment acquirer configured to acquire a travel environment of the vehicle, wherein the agent controller causes an aspect in which the sound image of the agent sound is localized to be changed when the travel environment of the vehicle acquired by the travel environment acquirer is changed or is predicted to be changed in the future.
US10994605B2 Systems and methods for reducing vehicle evaporative emissions
Methods and systems are provided for reducing an amount of fuel vapors that are routed to a fuel vapor storage canister during a refueling event, in response to an indication that a fuel dispenser that is dispensing fuel to a fuel tank is underperforming. In one example, a method comprises increasing a pressure in the fuel tank responsive to an indication that the fuel dispenser is dispensing fuel at a first rate that is at least a threshold amount below a second rate, without changing the first rate at which the fuel dispenser is dispensing the fuel. In this way, fuel vapor recirculation may be improved and an amount of fuel vapors routed to the canister reduced, which may thus reduce opportunities for release of undesired evaporative emissions to atmosphere.
US10994603B2 Tractor
A tractor including: an engine mounted on a traveling body; a post-processing device configured to purify exhaust gas of the engine; and a tail pipe long in an up-down direction and configured to emit exhaust gas having passed through the post-processing device to the outside. The post-processing device is arranged in a standing posture in front of an operation unit on the traveling body so that the exhaust gas flows from the bottom to the top. An upwardly protruding outlet pipe is provided on an upper surface side of the post-processing device. The inner diameter of an exhaust gas inlet side of the tail pipe is set larger than the outer diameter of the outlet pipe which is inserted and communicated with the exhaust gas inlet side of the tail pipe.
US10994600B2 Layout structure for front compartment of hybrid vehicle
A front compartment is provided with an engine, an air cleaner, a radiator, a reservoir tank, a motor unit, an auxiliary battery, and an EFI-ECU. The engine, the reservoir tank, the motor unit and the EFI-ECU are aligned in a vehicle's width direction. The air cleaner and the auxiliary battery are also aligned in the vehicle's width direction. The air cleaner is located in front of the motor unit. The motor unit includes a power control unit and a transaxle. The air cleaner is located in front of the power control unit. The auxiliary battery is located diagonally forward to left of the motor unit.
US10994598B2 Power transmission apparatus for electric vehicle
A power transmission apparatus for an electric vehicle having a motor as a power source may include: first and second input shafts coaxially disposed with a motor shaft of the motor and selectively connected to the motor shaft; an output shaft disposed in parallel with the first and second input shafts; and a planetary gear set disposed on the output shaft and including: a rotation element fixedly connected to the output shaft, and two rotation elements receiving torques from the first and second input shafts through respective external gear sets.
US10994595B2 Engine mount pendulum support device
The invention relates to an engine mount pendulum support device for supporting an engine relative to the body of a motor vehicle. The engine mount pendulum support device comprises a first attachment region for attaching the engine mount pendulum support device to the body, which attachment region comprises a first attachment surface for contact with the body, a second attachment region for attaching the engine mount pendulum support device to the body, which attachment region comprises a second attachment surface for contact with the body, a third attachment region for attaching the engine to the engine mount pendulum support device, wherein the first attachment region and the second attachment region are elastically connected to the third attachment region via a first elastic mount and via a second elastic mount, wherein the first attachment region and the second attachment region are firmly connected to each other by a connection member.
US10994592B2 Sunshade for a vehicle
A sunshade is configured to extend over a portion of an operator area of the vehicle and includes a frame configured to be removably coupled to mounts for side view mirrors of the vehicle and a body coupled to the frame. At least a portion of the body is configured to move between a raised position and a lowered position relative to the vehicle.
US10994589B2 Electric vehicle
An electric vehicle includes an electric motor, an electrical storage device, an air-conditioning apparatus and a controller. A coolant circuit of the air-conditioning apparatus has a compressor, an outdoor heat exchanger, an expansion valve for cooling, and an evaporator. The evaporator has a heat storage member. In a case in which regenerative braking by the electric motor is performed when the state of charge of the electrical storage device is the predetermined value or more, the controller controls the air-conditioning apparatus such that a temperature of the evaporator is decreased so as to be lower than a temperature of the evaporator when a state of charge of the electrical storage device is less than a predetermined value.
US10994586B2 Vehicle air-conditioning device
A vehicle air-conditioning device is a heat pump type vehicle air-conditioning device including an external heat exchanger that performs heat exchange between refrigerant flowing the inside thereof and outside air. With the vehicle air-conditioning device, a controller functions as a temperature-difference calculation unit that calculates the temperature difference ΔT between the refrigerant in a refrigerant flow path on the exit side of the external heat exchanger and the outside air, and in addition, the controller functions as a frost formation determination unit that determines that frost formation is caused on the external heat exchanger on the basis of the elapsed time to of a state in which the temperature difference ΔT is equal to or larger than a frost-formation temperature difference at which the frost formation may be caused on the external heat exchanger.
US10994585B2 Vehicle air-conditioning system
A vehicle air-conditioning system, including: a DC-to-AC inverter, for supplying alternating current to the alternator of the vehicle from a battery, for rotating the wheel of the alternator; mechanical connection between the alternator wheel and a wheel of the air-conditioner of the vehicle; and an operating element, for user-operating the DC-to-AC inverter and the clutch of the mechanical connection, thereby operating the air-conditioner without power of the engine wheel.
US10994584B2 Centralized energy module for vehicle
A centralized energy module for a vehicle includes a base plate, a compressor mounted on the base plate, a first condenser mounted on the base plate at a location spaced part from the compressor and configured for condensing the refrigerant through heat-exchange with a first coolant supplied from a high temperature radiator while firstly passing the refrigerant supplied from the compressor, a second condenser connected with the first condenser and configured for condensing the refrigerant through heat-exchange with a second coolant supplied from a low temperature radiator while secondly passing the refrigerant supplied from the compressor, an expansion valve connected with the second condenser, and an evaporator mounted on the base plate, evaporating the refrigerant supplied from the expansion valve through heat-exchange with a third coolant which flows into the evaporator and supplying the evaporated refrigerant to the compressor.
US10994576B2 Rotary joint and pressure regulation system for tires
A rotary joint is configured to transfer a fluid between two entities, one of which is in rotary motion with respect to the other. The rotary joint comprises a cylindrical internal element, apt to be fixed to the entity in rotary motion, and a plurality of annular external elements. The external elements comprise at least two head elements, at least two housing elements of respective gaskets, two bearing elements, and at least one fluid inlet. The fluid inlet is placed between said two bearing elements. Housing elements of respective gaskets are arranged externally to the bearing elements, and head elements are arranged externally to the housing elements. The gaskets define an annular shaped sealed area. The sealed area is accessible on one side through said fluid inlet and on the other side through at least one fluid passage channel passing through the body of said internal element.
US10994574B2 Pneumatic tire
A pneumatic tire comprises main grooves extending in the tire circumferential direction. Grooves in vehicle inner and outer side center land portions are all narrow grooves. Vehicle inner side center land portion narrow grooves open to a vehicle center main groove at a first end, open to a vehicle inner side main groove at a second end, and bend in a tire circumferential direction. The narrow grooves in the vehicle outer side center land portion comprise vehicle outer side center land portion outer narrow grooves that open to a vehicle outer side main groove at a first end and terminate within the vehicle outer side center land portion at a second end and vehicle outer side center land portion inner narrow grooves that open to the vehicle center main groove at a first end and terminate within the vehicle outer side center land portion at the second end.
US10994572B2 Bicycle wheel hub and related hub assembly
A bicycle wheel hub for mounting a brake disc in relation to a spoke-holding flange. The hub has a connection portion with a first annular sector that is axially external with respect to the spoke-holding flange and a second annular sector that is axially external with respect to the first annular sector. A circumferential groove axially arranged between the first and the second annular sectors.
US10994566B1 Paper processing device
A paper processing device includes a casing, a transfer roller assembly and a paper pressing mechanism. The casing includes a paper placement platform. The plural papers from a printing device are transferred to the paper placement platform by the transfer roller assembly. The paper pressing mechanism is located under the casing. The paper pressing mechanism includes a support frame, a pressing bar, a driving mechanism and a linking mechanism. The pressing bar includes a protrusion block. The protrusion block is penetrated through an opening of the casing. The protrusion block and the paper placement platform face each other. The linking mechanism is connected between the driving mechanism and the pressing bar. While the linking mechanism is driven by the driving mechanism, the pressing bar is moved linearly relative to the support frame, and the protrusion block is moved from an initial position to a target position.
US10994564B2 Enhanced method for product marking
A layline labeling process includes providing a layline material including a carrier film and a plurality of ink regions applied to the carrier film; applying a laser to laser-treat the ink side of the layline material to remove a first portion of ink to form a pattern of labeling; applying the laser treated layline material to a product with the ink side against the product; curing the product; and removing the carrier film after curing, wherein a second portion of ink of the ink regions of the laser treated layline material not removed by the laser treatment remains bonded to an outer layer of the product. Because of the laser treatment to form the pattern of labeling where the ink has been removed from the carrier film, the labeling is visible by the contrast of the outer layer of the product where the ink was burned away, against the remaining ink that has bonded to such outer product layer during curing.
US10994561B2 Head device, head position adjustment mechanism, and image forming apparatus
A head device includes a head and a holder. The head has a discharge port to discharge droplets to a medium. The holder is configured to hold the head and be rotatable about a first rotation shaft extending in a discharge direction of the droplets and rotatable about a second rotation shaft extending in a longitudinal direction of the head.
US10994557B2 Printing apparatus and control method
A printing apparatus includes a feeding unit, a pair of rollers, a printing unit, and a control unit. The control unit can execute skew correction. The control unit can execute control to convey a preceding printing medium and a succeeding printing medium by the pair of rollers in a state in which a trailing edge portion of the preceding printing medium and a leading edge portion of the succeeding printing medium overlap. The control unit sets an execution timing of the skew correction for the succeeding printing medium based on positions of the preceding printing medium and the succeeding printing medium if a predetermined condition is met. The predetermined condition is that the preceding printing medium reaches a position at which a remaining print range for the preceding printing medium equals a predetermined print range.
US10994551B2 Printing apparatus and a control method
An object of the present invention is to prevent a sub tank the does not need replenishment from being replenished with ink. The present invention is a printing apparatus that includes: a print head; a sub tank; a main tank; a supply valve; an atmosphere release valve; and one pump, and performs a replenishment operation to replenish the sub tank with ink from the main tank by driving the pump in a state where the atmosphere release valve is closed and the supply valve is open, wherein a second ink, and a third ink, and in a case where replenishment of a first ink and the third ink is necessary and replenishment of the second ink is not necessary, the atmosphere release valve is opened after the supply valve of the first ink is closed and before the supply valve of the second ink is opened.
US10994549B2 Consumables including locking mechanisms
In an example, an apparatus includes a container to hold a quantity of a consumable resource. A mechanical drive coupling is attached to the container. The mechanical drive coupling includes a bore and a locking mechanism integrated into the bore. The locking mechanism locks the container to a drive mechanism when the bore and the drive mechanism are rotatably engaged.
US10994543B2 Inkjet printing apparatus and control method thereof
An inkjet printing apparatus includes a discharge head including orifices that discharge ink, a channel communicating with the orifices, a heating element that generates thermal energy for discharging the ink in the channel, a protection layer having a surface exposed to the channel and covering the heating element, and an electrode having a surface exposed to the channel; a tank that stores the ink to be supplied to the discharge head; an ink circulation unit that performs a circulation operation of circulating the ink between the discharge head and the tank; and a kogation removal unit that performs a removal operation of removing kogation generated around the heating element by applying a voltage between the protection layer and the electrode. The kogation removal unit performs the removal operation after the circulation operation is stopped.
US10994542B2 Inkjet printing apparatus
An inkjet printing apparatus includes a print head, to which a protective member configured to protect an ejection opening surface is attachable, and a head holder configured to hold the print head detachably. The inkjet printing apparatus further includes a guide portion provided in the head holder and configured to guide, in a width direction, the print head with the ejection opening surface protected by the protective member. The guide portion guides the print head with the protective member attached up to a predetermined position in the width direction and guides only the print head ahead of the predetermined position to prevent the protective member from exceeding the predetermined position.
US10994539B2 Fluid flow structure forming method
A method for forming a fluid flow structure may include positioning rows of micro devices in a mold, wherein each of the micro devices comprising a chamber layer in which an ejection chamber is formed and an orifice layer over the chamber layer in which an orifice is formed. The method may further include molding an amorphous body to encapsulate the rows of the micro devices such that the amorphous body forms fluid channels such that each of the rows is fluidically coupled to a different one of the fluid channels.
US10994538B2 Liquid ejecting head and liquid ejecting apparatus
A liquid ejecting head has head units for ejecting a liquid from nozzles onto a medium that is relatively moved in a first direction are arranged in a second direction perpendicular to the first direction. The head unit includes: a nozzle row in which the nozzles are arranged in a third direction intersecting the first direction and the second direction; a pressure chamber which communicates with the nozzles; a pressure generation element which corresponds to the pressure chamber; a supply liquid chamber which communicates with the pressure chambers and into which the liquid to be supplied to each pressure chamber is introduced; an inflow port through which the liquid flows into the head unit; and an outflow port through which the liquid flows out of the head unit.
US10994537B2 Method and device for detecting the correct operation of the nozzles of a print head
A print head of an ink jet printer comprising: a cavity for the circulation of jets, delimited laterally by side walls, at least one nozzle for producing at least one ink jet in the cavity, at least one generator applying a charge to at least one ink jet, at least one electrode for sorting drops or segments of one or several of the jets intended for printing from drops or segments that are not used for printing, a slot, open onto the exterior of the cavity, a 1st gutter for recovering drops or segments not intended for printing, a 2nd gutter for recovering drops or segments that are not deflected and not intended for printing, this 2nd gutter comprising an input slot and at least one suction channel, an actuator in order to actuate the 2nd gutter, a 1st detector to detect an electrical charge of drops recovered in the 2nd gutter for recovering when the latter is in a closed position and/or a detector to detect, without contact, the passing of charged drops when the 2nd gutter is in an open position.
US10994536B2 Image recording apparatus
There is provided an image recording apparatus including: a head; a driving element; a controller configured to output, to the driving element, a driving signal having a first voltage level or a second voltage level greater than the first voltage level; and a moving mechanism causing one of the recording medium and the head to move relative to the other of the recording medium and the head. The controller sets the voltage level of the driving signal to be the first voltage level in a case that the controller causes the head to move relative to the recording medium at the first velocity; and the controller sets the voltage level of the driving signal to be the second voltage level in a case that the controller causes the head to move relative to the recording medium at the second velocity.
US10994530B1 Printing device temperature management
In some examples, printing device temperature management may include ascertaining a print speed associated with a print job, and comparing the print speed to a print speed threshold. Printing device temperature management may further include actuating a power supply associated with a print bar at a start position of physical medium to be utilized for printing for the print job, or at or beyond a specified location along a path associated with traversal of the physical medium from the start position to a print zone to reduce an operational temperature associated with the print bar.
US10994528B1 Digital printing system with flexible intermediate transfer member
Methods for printing using printing systems comprising a flexible intermediate transfer member (ITM) disposed around a plurality of guide rollers at which encoders are installed, and an image-forming station at which ink images are formed by droplet deposition by print bars onto the ITM, can include measuring a local velocity of the ITM under one of the print bars, determining a stretch factor for a portion of the ITM based on a relationship between an estimated stretched length fixed physical distance between print bars, controlling an ink deposition parameter according to the stretch factor so as to compensate for stretching of the reference portion of the ITM.
US10994527B2 Planarity alignment of stencils and workpieces
An alignment system for a workpiece printing machine comprises a stencil support and a workpiece support, and a planarity control mechanism having at least two actuators arranged to effect relative rotation of the stencil support and workpiece support about both the horizontal axes.
US10994522B2 Silicone sheet
A silicone sheet 1 of the present invention is a silicone sheet that is at least one selected from a silicone gel sheet and a silicone putty sheet. The silicone sheet has a Shore 00 hardness of 75 or less. The silicone sheet is cut in a thickness direction and cut faces 5a-5m and 6a-6f of the silicone sheet are adjacent to each other without gap. The cut faces of the silicone sheet are non-tacky, and the silicone sheet is separable at the cut faces. Preferably, the cut faces have a tackiness of 0.6 N or less based on a tackiness checker. The mounting method of the present invention is a method of mounting the above silicone sheet by pick and place mounting using an automatic mounting machine.
US10994521B2 Rubber product with wear indicating layers
A polymeric product with at least one surface subject to wear or abrasion, at least a portion of which product includes microcapsules of an indicator substance which is released to indicate a state of wear has been reached. The microencapsulated indicator substance may be a fragrance or a colorant. The indicating portion or zone may be a layer or a thin sheet of microcapsules in rubber or in the polymeric material making up the body of the product. There may be more than one indicating layer or zone in the product. The various zones may contain different fragrances or colorants, which may provide progressive indication of the state of wear.
US10994520B2 Decorated dental appliances and methods for producing same
A method includes the steps of providing a disk, wherein the disk has a first side, a second side opposite the first side, and a profile, and wherein the disk includes an FDA-compliant plastic material that is configured to be formed into a dental appliance; providing a graphic part, wherein the graphic part includes: a first carrier film, and a graphic disposed on the first carrier film, providing a heat stamping press having a lower platen and an upper platen; positioning the disk on the lower platen; positioning the graphic part on the disk such that the graphic of the graphic part contacts a portion of the first side of the disk; and heat stamping the disk and the graphic part with the heat stamping press, thereby causing the graphic to fuse with the disk to produce a decorated disk.
US10994519B2 Foamed blow molded article
The invention is directed to a blow molded article. The article comprises at least three layers wherein layer A comprises polymer, layer B comprises a foam composition comprising high density polyethylene having a quotient of melt strength and apparent viscosity>2 cN/k.Pa.s and layer C comprises polymer wherein the layer comprising the foam composition is enclosed between two layers A and C and wherein the melt strength is determined as described in ISO 16790:2005 and the apparent viscosity is determined as described in ISO 11443:2014 and wherein the foam composition is produced with a physically blowing agent.
US10994514B2 Kinetic energy absorption method
A kinetic energy absorption method includes receiving a force from kinetic energy at a composite article and distributing a load associated with the force across a designated pattern of lower strength length portions or lower modulus length portions of fibers within the composite article, where the load is distributed by: plastically deforming a ply and a matrix material; separating multiple substantially parallel fibers at the lower strength length portions or plastically stretching the multiple substantially parallel fibers at the lower modulus length portions; and creating gaps in the ply where the multiple substantially parallel fibers are separated or creating shear boundaries in the ply where the multiple substantially parallel fibers are plastically stretched.
US10994512B2 Hybrid composite tube systems and methods
A hybrid composite tube includes a metallic tube, a first silica fiber layer positioned radially of the metallic tube, a fiber reinforced polymer layer positioned radially of the first silica fiber layer, and a second silica fiber layer positioned radially of the fiber reinforced polymer layer, wherein the first silica fiber layer thermally insulates the fiber reinforced polymer layer and the second silica fiber layer thermally insulates the fiber reinforced polymer layer.
US10994502B2 Lamination system and method using a plurality of static lamination heads
A manufacturing system includes a plurality of lamination heads statically positioned in end-to-end relation to each other and defining a lamination station, and configured to dispense a layup material along a dispensing direction. The manufacturing system also includes a lamination surface movable underneath the lamination station. The lamination heads are configured to sequentially apply the layup material onto the lamination surface and onto previously applied layup material as the lamination surface passes through the lamination station to thereby form a composite laminate having a stack of composite plies arranged in a desired ply stacking sequence defined by positions of the lamination heads relative to each other within the lamination station.
US10994497B2 System and method for increasing density of structural composites
In one embodiment, a method for making a high density structural composite includes depositing a plurality of fibrous materials on or adjacent a first plate or surface. A polymer liquid is deposited onto the plurality of fibrous materials to form a composite mixture. A first cyclic pressure is applied onto the composite mixture to compress the composite mixture. In some embodiments, the cyclic pressure may then be reduced to a valley pressure to complete a pressurization cycle. In some instances, the valley pressure may be below atmospheric pressure to induce trapped air and volatile gases to escape from the composite mixture before curing. The pressurization cycle may be repeated. A second pressure, which may be a constant pressure in some embodiments, may be applied to the composite mixture using, in some embodiments, a second plate until the polymer liquid has at least partially cured or partially solidified.
US10994490B1 Calibration for additive manufacturing by compensating for geometric misalignments and distortions between components of a 3D printer
A method for additive fabrication includes determining numerical calibration transforms for calibrating an imaging sensor and a printhead assembly to a common coordinate system, where at least some of the numerical calibration transforms include nonlinear transforms.
US10994485B2 Additive manufacturing device including a movable beam generation unit or directing unit
A device for manufacturing a solid article includes a beam generation unit, a control unit, a supply unit, a container containing a raw material arranged in multiple raw material layers arranged upon each other, such that a raw material surface is exposed to a beam. The beam is emittable by the beam generation unit according to instructions of the control unit. A heating surface heats the raw material surface to form a pre-heated raw material surface. The beam generation unit is disposed with a directing unit to direct the beam onto the pre-heated raw material surface. The beam generated by the beam generation unit passes through the heating surface onto the pre-heated raw material surface. The beam generation unit and/or the directing unit is movable relative to the raw material surface, such that the angle of the beam relative to the raw material surface substantially remains constant.
US10994481B2 Additive manufacturing system having in-head fiber-teasing
A head is disclosed for an additive manufacturing system having a support. The head may include a body connectable to and moveable by the support. The body may have a discharge end configured to discharge a composite material. The head may also include a wetting location inside the body at which a continuous reinforcement is wetted with a matrix to form the composite material, and a fiber-teasing mechanism located inside the body and upstream of the discharge end and the wetting location. The body and fiber-teasing mechanism may be configured to move together during movement of the support.
US10994480B2 Three-dimensional printer systems and methods
Disclosed are embodiments of a three-dimensional (3D) printer for building 3D objects with layer based, additive manufacturing techniques. The hot end can be moved in a horizontal plane parallel a planar printing surface of the printing bed while the printing bed can be moved perpendicular to the planar printing surface to print a 3D object. The hot end can be part of an extrusion guide assembly. The 3D printer can auto-level the printing bed.
US10994477B1 Optical scanning for industrial metrology
An approach to improving optical scanning increases the strength of optical reflection from the build material during fabrication. In some examples, the approach makes use of an additive (or a combination of multiple additives) that increases the received signal strength and/or improves the received signal-to-noise ratio in optical scanning for industrial metrology. Elements not naturally present in the material are introduced in the additives in order to increase fluorescence, scattering or luminescence. Such additives may include one or more of: small molecules, polymers, peptides, proteins, metal or semiconductive nanoparticles, and silicate nanoparticles.
US10994476B2 Process for the realization of a window/door framework for walls of buildings
The process for the realization of a window/door framework (1) for walls of building comprises a molding step of a perimeter frame (2) by means of a three-dimensional molding device (5, 6, 7, 9), wherein the perimeter frame (2) comprises a plurality of perimeter sides made in a single monolithic body.
US10994473B2 Fabrication of three dimensional structures by in-flight curing of aerosols
A method for fabricating three-dimensional structures. In-flight heating or UV illumination modifies the properties of aerosol droplets as they are jetted onto a target surface. The UV light at least partially cures photopolymer droplets, or alternatively causes droplets of solvent-based nanoparticle dispersions to rapidly dry in-flight, and the resulting increased viscosity of the aerosol droplets facilitates the formation of free standing three-dimensional structures. This 3D fabrication can be performed using a wide variety of photopolymer, nanoparticle dispersion, and composite materials. The resulting 3D shapes can be free standing, fabricated without supports, and can attain arbitrary shapes by manipulating the print nozzle relative to the target substrate.
US10994471B2 Sleeve applicator system and method
The present invention is related to a sleeve applicator system for applying a heat-shrinkable sleeve to an object that moves in a first direction. The present invention further relates to a corresponding method.According to the invention, a second mandrel is mounted in a flexible manner to a first mandrel. A second drive system is used for moving the heat-shrinkable sleeve from the first mandrel over the second mandrel towards the object.The second drive system is further configured to push the second mandrel such that the second mandrel moves along with the moving object during the application of the sleeve.
US10994470B2 Structure stamp, device and method for embossing
A structure stamp has a flexible stamp which has a microstructured or nanostructured stamp surface for embossing of an embossing structure which corresponds to the stamp surface on an embossing surface, and a frame for clamping the stamp. Moreover, the invention relates to a device for embossing an embossing pattern on an embossing surface with the following features: a stamp receiver for accommodating and moving a structure stamp, an embossing material receiver for accommodating and placing an embossing material opposite the structure stamp, and an embossing element drive for moving an embossing element along the structure stamp.
US10994469B2 Dendrimer laser
A distributed feedback laser having a conjugated dendrimer as the active lasing component, and a method for patterning conjugated dendrimers.
US10994468B2 Foldable composite structures
Foldable composite structures and methods for fabricating foldable composite structures are provided. For example, a method comprises selectively applying a rigidifying substance to a sheet of composite material to define a plurality of hinges; allowing the rigidifying substance to cure; and folding the sheet of composite material along the hinges to form the composite structure. As another example, a method comprises laying out flat a sheet of composite material; masking a plurality of hinges on the sheet; applying a polymer to a sheet face; curing the polymer; removing the masking; and folding the sheet along the hinges to form the composite structure. An exemplary foldable composite structure comprises a planar sheet of composite material folded to define a plurality of surface segments and a plurality of hinges. A portion of the hinges form peaks and the remainder of the hinges form valleys. The hinges are defined between adjacent surface segments.
US10994465B2 Rigid connecting device for connecting the upper and lower surfaces inside an oil tank and production method of the oil tank
A rigid connecting device for connecting the upper and lower surfaces inside an oil tank includes a connecting rod. The upper and lower sides of the connecting rod are each provided with a connecting end surface. The connecting end surface is provided with material-passing hole. The outer surface of the rigid connecting device is covered with high-density polyethylene. The upper and lower surfaces of the oil tank are connected by a connecting rod, and such arrangement is locally applied to areas where the rigidity of the oil tank is poor, so there are more effective space. The part of the rigid connecting rod contacting with the oil fuel is made of high-density polyethylene, so the requirements of strength and anti-corrosion can be satisfied.
US10994460B2 System and method for molding amorphous polyether ether ketone
A method for molding amorphous polyether ether ketone including steps of preparing a molten mass including polyether ether ketone, cooling a mold assembly to a temperature of at most about 200° F., and injecting the molten mass into the cooled mold assembly.
US10994457B2 Method for manufacturing massage wear-resistant treadmill deck and finished product thereof
A method for manufacturing a massage wear-resistant treadmill deck and a finished product thereof are provided. The method includes step 1: providing a mold, the mold having a plurality of cavities thereon, a wear-resistant material being injected into the cavities of the mold; step 2: placing a deck in the mold so that the wear-resistant material is bonded to a surface of the deck to form a plurality of massage protrusions on the deck; and step 3: demoulding the deck from the mold, the surface of the deck being formed with the massage protrusions to form the massage wear-resistant treadmill deck. A wear-resistant layer having the massage protrusions is first formed in the mold, and then the deck is placed into the mold to bond with the wear-resistant layer to form the massage wear-resistant treadmill deck. The manufacturing cost is reduced and the manufacturing mobility is improved.
US10994453B2 Retaining device including reinforced retaining elements
A retaining device includes a base (51) extending in a longitudinal direction and presenting a top face (511) and a bottom face (512); and a plurality of retaining elements extending from the top face (511) of the base (51), each of the retaining elements being formed by a stem (52) surmounted by a head (53), the stem (52) having a bottom end (521) connected to the base (51), and a top end (522) opposite from the bottom end (521), the head (53) surmounting the top end (522) of the stem (52), and having a bottom face facing towards the base and a top face opposite from the bottom face.
US10994452B2 Powder slush molding machine and powder slush molding method
There are provided a powder slush molding machine that preheats a mold using the transfer time of the mold and may be reduced in size, and a powder slush molding method using the powder slush molding machine.There are provided a powder slush molding machine and a powder slush molding method using the powder slush molding machine. The powder slush molding machine includes: a mold heating portion that heats a mold so that the temperature of the mold is set to a value equal to or higher than a predetermined temperature; a powder slush portion that sprays a molding resin, while powdering the molding resin, to mold a sheet-like material having a predetermined thickness on the inner surface of the heated mold; a mold cooling portion that cools the mold so that the temperature of the mold is equal to or lower than a predetermined temperature; a mold working portion that separates the cooled sheet-like material from the mold; and a transport device that moves the mold between the respective portions. A preheating device for heating the mold is provided at a part of the transport device.
US10994448B2 Station and method for curing a tread strip
Station (7) and method of curing for a tread strip (2); provided are: a flat curing mold (9) which is composed of a lower shell (10) and an upper cover (11); and an extractor element (17) which is suitable for extracting the cured tread strip (2) from the lower shell (10) after the curing operation; the cured tread strip (2) has a first wall (13), which has a relief design and is in contact with the lower shell (10), and a second wall (14) which is opposite the first wall (13), and is in contact with the upper cover (11); the extractor element (17) is suitable for adhering to the second wall (14) of the tread strip (2) along the entire length of the second wall (14) itself; and the extractor element (17) is movable perpendicularly with respect to the second wall (14) of the tread strip (2) in order to simultaneously raise the whole tread strip (2) from the lower shell (10).
US10994447B2 Seal structure of mold for manufacturing composite material structure
A seal structure is used in a mold constituted by a plurality of segments to manufacture a hollow composite material structure. In the seal structure, a seal member formed in a line shape having ends is inserted in a seal groove provided on at least one of adjacent side surfaces of the segments. A lip portion is provided at a seal upper portion of the seal member such that at least a tip end of the lip portion projects to an outside of the seal groove. When the adjacent side surfaces of the segments are coupled to each other, the seal member is crushed in a cross sectional direction by the other of the adjacent side surfaces of the segments. With this, complication of the manufacture of the composite material structure can be suppressed or avoided while realizing a satisfactory sealed state between the adjacent segments.
US10994440B2 Wear resistant coatings for tool dies
A tool die for forming a green ceramic body. The tool die has a wear resistant coating that is deposited on a substrate and has an outer or free surface having a morphology that provides a mean roughness in a range from about 0.03 μm up to about 0.8 μm Rq. In one embodiment, the wear resistant coating has multiple alternating layers of fine grained and coarse grained materials. Methods of making the tool die and wear resistant coating are also provided.
US10994437B2 Hardened steel counter-die
A counter-die includes a body portion comprised of a relatively soft plate material that is substantially planar for use in a die converting process. The counter-die is comprised of a metallic material that includes a bearing surface that is work-hardened over time in a repeated die converting process to provide a work-hardened outer layer that exhibits a medium-hard to hard characteristic as compared to the body portion of the counter-die.
US10994431B2 Ambulatory cutting device
An ambulatory cutting device is provided. The ambulatory cutting device provides a blade mounted, by way of a blade holding assembly, to a wheeled frame. The wheeled frame has handles for a user to push the wheeled frame along a surface supporting a roofing membrane or other cuttable membrane, wherein the blade holding assembly maintains the mounted blade at an elevation just below the supporting surface so that the membrane is cut as a user pushes the wheeled frame.
US10994429B2 Retractable cutting tool
The present invention provides a retractable cutting tool, which includes: a cutting tool housing, the interior thereof forming a cavity; a blade exit portal, penetrating through the cutting tool housing and communicating with the cavity; a blade holder, moved or locked in the cutting tool housing; a blade, mounted to the blade holder and disposed opposite the blade exit portal; when the blade holder is moved, the front end of the blade protrudes out of the cutting tool housing or retracts into the cutting tool housing through the blade exit portal; a blade holder moving device, for moving the blade holder in the cutting tool housing; and a protrusion length control device, for controlling the protrusion length of the blade outside the cutting tool housing.
US10994427B2 Robot with safety fence and robot system
A robot with a safety fence includes: a base; a movable part having a base end supported to the base so as to be rotatable about a first axis, and a tip end performing operation on an operation target; and a safety fence rotated about the first axis together with the movable part, and disposed on a rear side opposite to a front side of the robot with a safety fence where the tip end of the movable part performs operation. The safety fence is disposed in a position radially closer to the first axis than the farthest distance the tip end of the movable part travels from the first axis on the front side, and a position radially farther away from the first axis than the farthest distance a portion of the movable part travels from the first axis during operation, on the rear side.
US10994419B2 Controlling a robot in the presence of a moving object
A method, system, and one or more computer-readable storage media for controlling a robot in the presence of a moving object are provided herein. The method includes capturing a number of frames from a three-dimensional camera system and analyzing a frame to identify a connected object. The frame is compared to a previous frame to identify a moving connected object (MCO). If an unexpected MCO is in the frame a determination is made if the unexpected MCO is in an actionable region. If so, the robot is instructed to take an action.
US10994415B2 Robot with control system for discrete manual input of positions and/or poses
The invention relates to a robot, a robot control system, and a method for controlling a robot. The robot comprises a movable, multi-membered robot structure (102) that can be driven by means of actuators (101), at least one marked structural element S being defined on the movable robot structure (102), with at least one point PS marked on the structural element S. The robot is designed such that, in an input mode, it learns positions POSPS of the point PS and/or poses of the structural element S in a work space of the robot, the user exerting an input force FEING on the movable robot structure in order to move the structural element S, which is conveyed to the point PS as FEING,PS, and/or to the structural element S as torque MEING,S. A control device (103) of the robot is designed such that, in the input mode, the actuators (101) are controlled on the basis of a pre-defined space-fixed virtual 3D grid that at least partially fills the work space, such that the structural element S is moved with a pre-defined force FGRID (POSPS), according to the current position POSPS of the point PS in the 3D grid, to the adjacent grid point of the 3D grid or in a grid point space defined around the adjacent grid point of the 3D grid, the point PS of the structural element S remaining on said adjacent grid point or in said grid point space in the event of the following holding true: |FEING,PS|<|FGRID(POSPS) and/or, in the input mode, the actuators (101) are controlled on the basis of a pre-defined virtual discrete 3D orientation space O, where the 3D orientation space O=: (αi, βj, γk) where i=1, 2, . . . , I, j=1, 2, . . . J, k=1, 2, . . . , K is defined or can be defined by a pre-defined angle αi, βj, γk, in such a way that the structural element S is moved with a pre-defined torque)(SO ROM according to the current orientation ORS of the structural element, towards the adjacent discrete orientation of the 3D orientation space O=: (αi, βj, γk), S, the structural element remaining in said adjacent discrete orientation of the 3D orientation space O in the event that the following holds true: |MEING,S|<|MO(ORS).
US10994414B2 Control device and robot system
A control device for controlling a robot including an arm driven via a reduction gear by a motor generating a drive force, the control device comprising a processor that is configured to execute computer-executable instructions so as to control a robot, wherein the processor is configured to perform speed control on the arm by using an input detection value from an input position detection sensor which detects an input side operation position of the reduction gear, and an output detection value from an output position detection sensor which detects an output side operation position of the reduction gear.
US10994408B2 Device capable of simulating limb of humanoid robot
A device capable of simulating a limb of a humanoid robot includes a vertically arranged guiding rail, a lower block fixed to the lower end of die guiding rail, an upper block slidably connected to rail, a lower linkage bar rotatably coupled to the lower block, an upper linkage bar rotatably coupled to the upper block, a joint module located between and rotatably coupled to the lower linkage bar and the upper linkage bar, a sensor configured to measure a force exerted on the joint; and a data processing module electrically connected to the sensor and configured to receive data from the sensor to determine a value of the force.
US10994407B2 Self-driving storage device
A self-driving storage device for storing and/or transporting body components of motor vehicles, base modules of motor vehicles, or motor vehicles in a final or partially assembled state, the self-driving storage device comprising a base element and a support structure which is arranged on the base element, is designed to receive the body components or the motor vehicles in a final or partially assembled state, and has a plurality of storage spaces with movable storage base elements, wherein the storage device has a movement device which is arranged on the base element and is designed such that the storage device can be moved omnidirectionally in a self-driving manner, in a floor-bound manner.
US10994406B2 System comprising an electrically operated handheld device and a transport case for the handheld device, and method for operating a handheld device
The invention relates to a system which comprises an electrically operated handheld device, which particularly takes the form of a hot-air handheld device or handheld grinding device, and a transport case for the handheld device, wherein the transport case comprises at least one first case shell. Here, the at least one first case shell comprises an outer side, the case shell comprising in its outer side a depression for partially accommodating the handheld device, and the depression extending in the direction of a stowage space of the transport case.
US10994403B2 Hand-held power tool comprising a gearshift unit
In a hand-held power tool with a drive unit comprising at least one drive motor and a transmission coupled to the drive motor for driving a working tool, wherein the transmission can be shifted between at least two different gear ratios, a communication interface is provided for communication with a guide unit operable by a user and designed to receive gearshift instructions from the guide unit for shifting the transmission between the two different gear ratios according to the specific use.
US10994395B1 Loop-type band clamp installation tool
Tool for securing a loop-type band clamp around an object. Turning a drive screw displaces an upper jaw relative to a lower jaw of the tool. An alignment component is inserted through holes in band clamp tabs and then a fastener engages a receiving end of the alignment component. An opening in the lower jaw receives the fastener and an opening in the upper jaw receives an upper segment the alignment component. The upper and lower jaws compress the tabs by operation of the drive screw, closing the loop around the object. While the tabs are compressed, the alignment component is separated from the fastener and a clamp fastener is inserted through the tab holes and mated with the fastener. The upper segment of the alignment component is removed from the upper jaw. The upper and lower jaws are removed from the band clamp by operation of the drive screw.
US10994388B2 Machine tool for multiple working of surfaces of bodies
A machine tool for multiple working for material removal from surfaces of bodies including a working station in which a plurality of rotary tools are positioned around a feed trajectory of said bodies; and guide means in which the bodies to be worked are made to translate one after another along said feed trajectory with a predetermined orientation position. At least one pair of rotary tools of said working station, intended to interact with the surfaces to be worked, inside slits in said bodies, in combination with each other and with guide means provided with partitions, help to keep said bodies in position during their related transit through said working station.
US10994382B2 Support arrangement for supporting a workpiece
A support arrangement for supporting a workpiece at a processing device during processing of the workpiece. The support arrangement comprises: a fixating means adapted to arrange an abutment surface of the support arrangement in contact with one side of the workpiece when another opposite side of the workpiece abuts one or more fences of the processing device, a locking means adapted to lock the fixating means in a contact position where abutment surface of the support arrangement abuts the one side of the workpiece when another opposite side of the workpiece abuts the one or more fences of the processing device, and a connecting means adapted to connect the support arrangement with the processing device. The support arrangement may be applied e.g. at saw devices for fixating a log to be sawn, in order to achieve a satisfactory result for a sawing process, e.g. planks with a high dimensional accuracy it is important that the workpiece is reliably fixated during the sawing process.
US10994381B2 Controller, data generation device, control method, and control program
To provide a controller, a data generation device, a control method, and a control program allowing a part of a machining program to be changed easily. A controller comprises: a storage unit that stores change designation data describing a command value in association with respective identifiers indicating at least one block among multiple blocks constituting a machining program for a machine tool; a change unit that reads the multiple blocks in the machining program sequentially, and changes the block indicated by the identifier based on the command value described in the change designation data; and an analysis unit that analyzes the block changed by the change unit, and generates execution data.
US10994378B2 Die body apparatus and methods
A die body apparatus (101) includes a first discharge member (105) configured to be bonded with respect to a base member (103) such that aligned elongated openings (209) of the base member (103) and first discharge member (105) provide a plurality of elongated feed passages placing a plurality of feed holes (106) of the base member (103) in fluid communication with a first honeycomb network of discharge slots (415) of the first discharge member (105). In further examples, methods of assembling a die body apparatus (101) includes the step of bonding a selected discharge member (105) of at least one discharge member with respect to a base member (103). In further examples methods of extruding batch material into a honeycomb body includes the steps of bonding a selected discharge member (105) with respect to a base member (103) and extruding a quantity of batch material through the die body apparatus (101) into an extruded honeycomb body with a honeycomb network of channels.
US10994377B1 Method for manufacturing a railcar body
A method for manufacturing a railcar body includes assembling an underframe assembly, side walls, a roof and end walls made from laser cut sheet and plate components where the assemblies made from sheet components are robotically laser welded by solely using melt-through welds and where the assemblies made from plate components are robotically laser welded using solely butt welds.
US10994372B2 Machine for laser working of tubes and profiled sections with a scanning system for scanning the tube or profiled section to be worked
The machine includes a working head with a focusing device arranged to focus a laser beam on the surface of a tube or profiled section to be worked, a carriage and a scanning system arranged to scan a portion of the outline of the cross-section of the tube or profiled section. The working head and laser scanning module are mounted on the carriage, and the carriage is able to translate with respect to the tube or profiled section in longitudinal and transverse directions such that the working head and laser scanning module translate with the carriage. The scanning system includes at least one laser scanning module including a laser emitter arranged to emit a light blade with which to illuminate a portion of the tube or profiled section and a camera arranged to acquire an image of the portion of tube or profiled section illuminated by the light blade.
US10994366B2 Repair method and repair material
A repair method that includes covering a damaged part of a member to be repaired with a repair material, and heating the repair material to a predetermined temperature to form an alloy layer. At least the surface of the member to be repaired is a first metal such as Cu. The repair material includes a second metal such as Sn. By the heating, the surface of the member to be repaired is integrally joined with a layer of an intermetallic compound and an alloy having a melting point higher than a melting point of either of the first metal or the second metal.
US10994364B2 Spot welded joint and spot welding method
A spot welded joint in which a high CTS is obtained even if including one or more high strength steel sheets and a method of welding of the same, that is, a spot welded joint 1 including a plurality of steel sheets, wherein one or more steel sheets is a tensile strength 750 to 2500 MPa high strength steel sheet and, at a cross-section in the sheet thickness direction of the steel sheets, when defining superposed surfaces of a high strength steel sheet S1 arranged at an outermost side and another steel sheet 1B as the “plane A” and defining a plane passing through a point of one-half of a distance between a nugget end position E of a high strength steel sheet S1 side on the line L1 in the sheet thickness direction and a crossing point O of the plane A and the line L1 and parallel to the plane A as the “plane B”, at a square area SA of sides of 30 μm centered about a crossing point X of a line L2, which is separated by 250 μm to the heat affected zone side from a tangent at any position on a nugget end line NEL sandwiched between the plane A and plane B and parallel to that tangent, and a line L3 vertical to L2 included in a heat affected zone 4 having a high strength steel sheet S1 as a base material, an average value of widths of the blocks formed from lath martensite is 0.5 to 7.0 μm.
US10994362B2 Tandem arc welding head and a welding arrangement for overlapping arcs to a cold wire electrode
An arc electric welding head comprising a first contact device housing a first duct for feeding a first electrode and providing electrical contact between a first power source and said first electrode, a second contact device housing a second duct for feeding a second electrode and providing electrical contact between a second power source and said second electrode, said first and second contact devices being electrically insulated from each other, said first and second ducts being parallel.
US10994361B2 Stepped design weld joint preparation
A weld with a stepped configuration is provided. The stepped configuration may be machined from a substrate to form a weld preparation which may accommodate a stepped weld. The weld with a stepped configuration and a controlled procedure exhibits improved service life and improved damage tolerance. A welded joint with a stepped configuration, a joined component with a stepped configuration, and method of welding a stepped configuration are also provided.
US10994360B2 Apparatus for feeding welding wire and process gas to a welding device
The invention relates to an apparatus for feeding welding wire and process gas to a welding device comprising a wire feeding nozzle (1), which has a welding wire channel (4), a nozzle block (2), which is releasably connected to the wire feeding nozzle (1), a profile (3), which is releasably or fixedly connected to the nozzle block (2), has a welding wire channel (6) and can be connected to a welding wire conveying device, wherein the process gas channel (9) of the process gas feeding device is arranged at least partially within the profile (3) and the nozzle block (2) is provided with multiple bores (7), which adjoin the process has channel (9) and are arranged parallel to or at an acute angel of ±5° to the welding wire chancel (4) of the wire feeding nozzle (1) and around the wire feeding nozzle (1). In this case, the nozzle block (2) is formed cylindrically in the direction of an end (14) having the wire feeding nozzle (1), wherein the bores (7) arranged within the nozzle block run out into depressions (15) on the surface of the nozzle block (2).
US10994355B2 Metal laminating and molding method
A metal laminating and molding method molds a 3-dimensional molded object formed by sequentially laminating a plurality of metal layers. The metal laminating and molding method is accomplished by repeatedly performing a unit process including a metal layer laminating process of laminating the metal layer constituted by welding beads formed through arc welding and a removal process of removing impurities from a surface of the metal layer laminated in the metal layer laminating process. When the unit process is repeated, the metal layer laminating process is performed again such that a new metal layer is laminated on the surface of the metal layer from which impurities have been removed in the removal process.
US10994354B2 Slitted sandwich insulated arc saw blade having a translational rail assmbly and direct coupling to a rotational pivot pin
Arc saw blades and systems and methods for segmenting components utilizing improved arc saw blades.
US10994349B2 Large diameter travelling pipe cutter
According to an aspect of the present disclosure, a low profile travelling pipe cutter is provided which is adapted to perform at least one of cutting and beveling a hollow vessel while traveling around the vessel using a cutting tool mounted thereon. The pipe cutter includes inner and outer carriages, a capstan assembly attached to the outer carriage to which a feed cable is attached, and rollers attached to the outer carriage to which a tension cable is attached. The force adjustment assembly changes the vertical position of the outer carriage relative to the inner carriage to compensate for the pipe cutter going inwardly and outwardly as it travels around a hollow vessel in order to maintain constant pressure caused by the lever tension interface. A guard assembly is provided for covering and uncovering the cutting tool during cutting.
US10994348B2 System and method for cutting to length long rolled products coming from different strands of a rolling mill
A system for cutting to length at least two strands of long rolled products (3, 5) preferably coming from a hot rolling mill. The system includes shears comprising at least two rotatable drums (4,6), each drum having a cutter (8,8′,10,10′) arranged to cut simultaneously at least two strands of long rolled products into finished segments. The system further includes at least two movable guides (12,14), each including at least two channels, each guide arranged to receive and guide at least one strand (3,5) of long product. The guides are movable between a position wherein, in operation, the strands of long product are located in positions either outside of the trajectory of the cutters in a position wherein the strands cannot be cut or wherein the strands are located on the trajectories of the cutters and can be cut by the cutters.
US10994346B2 Indexable drilling tool
An indexable drilling tool includes a cutting insert and a body. The body has a cylindrical shape. The body has a chip discharge groove and a tip seat. The chip discharge groove is in an outer circumference of the body. The tip seat is at a distal end of the body. The tip seat where the cutting insert is placeable wherein. Among wall surfaces constituting the chip discharge groove, a wall surface facing in a direction opposite to a rotating direction of the body. The wall surface has a bulging portion at a distal end thereof. The bulging portion protrudes so as to cover a part of a top surface of the cutting insert. A maximum gap between the bulging portion and the top surface of the cutting insert is smaller than a height of a wall constituting the tip seat.
US10994343B2 Changer device for clamping heads
A changer device for a clamping head having a base and pivoting elements pivotably articulated on the base and which in each case possess at least one engagement portion for impinging clamping jaws of the clamping head with a force. The changer device has a coupling transmission which per pivoting element possesses at least one coupling tab attached so as to be pivotably movable on the respective pivoting element. The changer device has a handle which for the purpose of simultaneous repositioning of the pivoting elements in relation to the base is movable in a relative manner. The handle is locationally fixed in relation to one of the coupling tabs such that a pivoting movement of the handle directly causes pivoting of the coupling tab and indirectly causes pivoting of the further coupling tab such that a pivoting movement of the pivoting elements and the engagement portions is caused.
US10994341B2 Surface-coated cutting tool and method for manufacturing same
A surface-coated cutting tool includes a base material and a coating film provided on a surface of the base material, wherein the coating film includes a first alternating layer provided on the base material and a second alternating layer provided on the first alternating layer, the first alternating layer includes A and B layers, the second alternating layer includes C and D layers, each of one or plurality of the A layers is composed of a nitride or carbonitride of AlaCrbM1(1-a-b), each of one or plurality of the B layers is composed of a nitride or carbonitride of AlcTidM2(1-c-d), each of one or plurality of the C layers is composed of a nitride or carbonitride of TieSifM3(1-e-f), and each of one or plurality of the D layers is composed of a nitride or carbonitride of TigSihM4(1-g-h).
US10994334B2 Method for preparing rice ear-shaped copper particles, rice ear-shaped copper particles prepared thereby, and conductive paste using same
The present invention relates to ear-of-rice-shaped copper particles. The technical gist thereof is a method of manufacturing ear-of-rice-shaped copper particles, ear-of-rice-shaped copper particles manufactured thereby, and a conductive paste using the same. The method includes a first step of preparing a copper precursor solution, a second step of adjusting the pH of the copper precursor solution, a third step of adding a zinc powder to the pH-adjusted copper precursor solution, a fourth step of synthesizing the ear-of-rice-shaped copper particles by stirring the copper precursor solution, to which the zinc powder is added, for a predetermined time, and a fifth step of separating, washing, and then drying the synthesized ear-of-rice-shaped copper particles.
US10994332B2 Lamination molding apparatus
A lamination molding apparatus includes an irradiator, a processing unit, and a cooling device. The irradiator irradiates a material layer with a beam to form a solidified layer. The processing unit includes a processing head having a tool that performs processing on the solidified layer, and a processing head driver moving the processing head at least in a horizontal direction. The cooling device is provided in the processing head and cools at least a part of a solidified body including an upper surface to a predetermined cooling temperature, and the solidified body is formed by laminating the solidified layer. The cooling device includes a cooling plate having a cooling surface being cooled to the cooling temperature, and the cooling surface is in close contact with the upper surface of the solidified body in a recumbent state with the cooling surface along the horizontal direction.
US10994330B2 Device, control system and filter module for producing die-cast parts, and method therefor
A device (10) for producing die-cast components with a die-casting mold (12) and a discharge device which is provided for controlled evacuation of a mold cavity and which includes at least one vacuum unit (18) and at least one suction line (20) which connects the die-casting mold. The suction line (20) terminates at a mold vacuum valve (21) in the mold cavity. The device is connected to a central control system (1). A filter module (2) is inserted in the at least one suction line (20) which contains at least one filter, a moisture sensor, and a pressure sensor.
US10994329B2 Device, control system and filter module for producing die-cast parts, and method therefor
A device (10) for producing die-cast components with a die-casting mold (12) and a discharge device which is provided for controlled evacuation of a mold cavity. The device (10) includes at least one vacuum unit (18) and at least one suction line (20) which connects the die-casting mold (12). The suction line (20) terminates at a mold vacuum valve (21) in the mold cavity. The device (10) is connected to a central control system (1). A filter module (2) is inserted in the at least one suction line (20). The filter module (2) contains at least one filter, a moisture sensor, and a pressure sensor.
US10994320B2 Method for marking workpieces and workpiece
In an embodiment, a workpiece includes a hot-formed metal body and a marking, wherein the marking comprises a phosphor and/or pigments which are at least partly arranged on the metal body and which exhibit a reflection behavior and/or a reflectance behavior and/or an albedo behavior deviating from the metal body.
US10994319B2 Bimetallic tube and method for manufacturing a bimetallic tube
The present disclosure relates to a bimetallic tube comprising a first metallic tube having an inner diameter and an outer diameter, and a second metallic tube having an inner diameter and an outer diameter, wherein the first metallic tube is arranged within and force-fitted to the second metallic tube and wherein the first metallic tube comprises a zirconium (Zr) based alloy and wherein the second metallic tube comprises an austenitic stainless steel. The present disclosure also relates to a method for manufacturing a bimetallic tube comprising the steps of providing a first metallic tube having an inner diameter and an outer diameter, providing a second metallic tube having an inner diameter and an outer diameter, wherein the outer diameter of the first metallic tube is smaller than the inner diameter of the second tube, insetting the first metallic tube into the second metallic tube, cold-drawing the first and second metallic tubes together, such that the first and second metallic tubes are force-fitted together.
US10994318B2 Sliding transport of rolled product with adaptation of friction
A pinch roll delivers a respective rolled product. A control device opens the pinch roll at a respective trigger time and at a respective transport speed of the respective rolled product. The control device determines the respective trigger time and/or the respective transport speed using a model that depends on a coefficient of friction. After opening the pinch roll, a measuring device detects iteratively a position or a derivation in time of the position of the respective rolled product. The detected positions or the detected derivations in time of the position are provided to the control device. The control device in dependency on the positions or the derivations in time of the position updates the coefficient of friction and uses the updated coefficient of friction for determining the respective trigger time and/or the respective transport speed for the next rolled product delivered by the pinch roll.
US10994313B2 Sanitary storage of thermal therapeutic wraps
A system including apparatus and methods for sanitizing or otherwise reducing biologics present on thermal therapeutic treatment wraps used for treating athletes after workouts or games, physical therapy patients after injury, and hospital patients after surgery is disclosed. The system includes a storage cabinet with an internal conveyor system that exposes each wrap to periodic sanitization or other biologic reduction means, such as ultraviolet light. This prevents growth of bacteria and mold. In some embodiments, warm air is blown into the storage cabinet to assist with drying the wraps.
US10994310B2 Liquid-dispensing, effluent shielding and microbe eliminating methods
A method of eliminating microbes in an overflow space in a sink having a sink basin may include obtaining a liquid dispensing and effluent shielding container assembly including a splash guard including a splash guard shield and an injection nozzle carried by the splash guard shield, the injection nozzle having an injection nozzle bore and at least one injection opening in the injection nozzle, the at least one injection opening, disposed in fluid communication with the injection nozzle bore; inserting the injection nozzle of the liquid dispensing and effluent shielding container assembly in the at least one overflow opening in the sink basin until the splash guard substantially covers the at least one overflow opening; and expelling the antimicrobial or cleaning agent liquid through the injection nozzle and the at least one injection opening and into the overflow space in the sink basin of the sink, respectively.
US10994309B2 System and method for identifying and transferring parcels from a first conveyor to a second conveyor
A system for identifying and transferring parcels includes a robot singulator configured to engage and transfer individual parcels in a bulk flow of multiple parcels on a first conveyor to a singulated stream of parcels on a second conveyor. The system further includes a vision and control subsystem, with a first camera for acquiring image data of the bulk flow of multiple parcels, and a computer that receives and processes the image data to identify and segment individual parcels, and then communicates instructions to the robot singulator to engage and transfer each of the individual parcels to the second conveyor. The system may further include a second camera for acquiring image data of the individual parcels to confirm placement on the second conveyor. The system may further include first and second indexing conveyors controlled by the vision and control subsystem for delivering parcels to the robot singulator.
US10994301B2 Method for constructing abradable coating, and shroud
A method for constructing an abradable coating comprises: a slurry layer formation step S2 in which a slurry layer 31 is formed on the surface of a base material 30 using a slurry containing ceramic particles and a solvent; a calcination step S3 in which the slurry layer 31 formed on the surface of the base material 30 is sintered and a sintered layer 35 to be a portion of an abradable coating layer 22 is formed; and a slurry removal step S5 in which extraneous slurry is removed after the abradable coating layer 22 has been formed on the surface of the base material 30, a plurality of the sintered layers 35 having been laminated in the abradable coating layer 22 through a plurality of repeated cycles of the slurry layer formation step S2 and the calcination step S3.
US10994298B2 Method for introducing an application medium into a weakening gap of a cover, and preferred application device
The invention relates to a method for introducing an application medium into a weakening gap (5) of a cover (4), such as a covering film or covering skin, wherein a cover (4) is provided which already has a weakening gap (5) formed completely over the length thereof on a first side (6), an application device (2) is positioned toward the first side (6), at a distance from the cover (4) and above the weakening gap (5), wherein a support is arranged in a supporting manner on a second side (7) of the cover (4), facing away from the application device (2), and an application of the application medium into the weakening gap (5) by the application device (2) is carried out. The invention further relates to an application device (1) for this method.
US10994294B2 Backpack sprayer with selectable internal pump
An internal pump backpack sprayer system includes a first tank, a second tank and a pump unit. The first tank includes a tank housing for holding a fluid. The second tank is received within the first tank and receives a pressurized fluid. The pump unit has a cylinder housing with first and second inlets and first and second outlets, a piston within a cylinder and a pressure discharge assembly. When the piston moves in an up-stroke, fluid is drawn from the first tank through the first inlet while all or some pressurized fluid is discharged through the pressure discharge assembly with a remainder being discharged to the second tank through the second outlet. When the piston moves in a down-stroke, fluid is drawn from the first tank through the second inlet while pressurized fluid is discharged to the second tank through the first outlet.
US10994293B2 Spray structure for portable atomizer
A spray structure for a portable atomizer includes: a case including an opening; a cover exposed through the opening of the case; a head portion placed in the case and coupled to the cover, the head portion including a discharge hole; and an elastic portion between the head portion and the cover, wherein the cover is configured to be rotated on a first axis by a first angle above the head portion to expose the discharge hole through the opening of the case and to be linearly moved in a second direction perpendicular to the first axis in a state in which the discharge hole is exposed.
US10994289B2 Showerhead with turbine driven shutter
The present disclosure is related to a showerhead. The showerhead includes a housing defining a fluid inlet and a chamber in fluid communication with the fluid inlet, a rotatable turbine received in the chamber and including an eccentric cam positioned on a downstream side of the turbine, and a shutter positioned on the downstream side of the turbine. The shutter includes a shutter body defining an oval-shaped aperture in which the eccentric cam is received such that the shutter oscillates along a rectilinear path as the turbine rotates.
US10994288B2 Water outlet terminal with purified water outlet
A water outlet terminal with the function of purified water outlet, includes a body and a mandrel. A raw water outlet hole and a pure water outlet hole are arranged on the end surface of the mandrel. The mandrel has a raw water inlet cavity and a purified water inlet cavity which are independent from each other. One end of the raw water inlet cavity and the purified water inlet cavity are communicated with the raw water outlet hole and the purified water outlet hole, and the other ends are the raw water inlet hole and the purified water inlet hole. The water outlet terminal has a purified water opening member with a first position and a second position corresponding to an open or closed state of purified water inlet hole, a cover assembly, with a purified water outlet passage in the geometric center of the assembly.
US10994284B2 Multi-stage fluidized-bed flotation separator
A system for concentrating particulate mixtures of hydrophobic and hydrophilic material in a fluid medium is presented. The system comprises a separation chamber comprising three or more processing compartments in series. Each processing compartment comprises a manifold for the introduction of teeter water that comprises a mixture of water and air bubbles, suspended solids that form a fluidized bed that is created by the upward movement of the teeter water through the suspended solids; and each processing compartment is independently operable. An overflow launder is located above the separation chamber and a dewatering compartment is located beneath the separation chamber.
US10994283B2 Electronic dust collecting apparatus and method of manufacturing dust collector
An electronic dust collecting apparatus is provided. The electronic dust collecting apparatus includes a charger, and a dust collector installed downstream of the charger, wherein the dust collector includes a dust collecting sheet including a plurality of first and second electrodes that are alternately arranged therein and a plurality of bent portions that are bent in a zigzag form in such a way that the plurality of first electrodes and the plurality of second electrode face each other.
US10994282B2 Electric precipitator air pollution control device
An electrostatic air precipitator for emission remediation including, a grounded frame connected to a housing having an upstream direction and a downstream direction with a first ionizing section, having at least a first set of ionizing members and a second set of ionizing members, where the ionizing members of the first set and the second set are electrically isolated from each other and electrically isolated from the grounded frame. Also, the ionizing members of the first set and the ionizing members of the second set are powered by separate power supplies and at least a first collector section is located downstream of the first ionizing section, and the first collector section has at least a first plurality of collector plates.
US10994281B2 Method for separating particles, separation apparatus, and separation system
Provided is a method for separating particles, a separation apparatus, and a separation system.
US10994275B2 Systems and methods for biological analysis
A system for processing a plurality of biological samples contains a support and a temperature controller. The suppose is configured to hold a case that includes an inner chamber and a substrate located within the inner chamber, the substrate containing a plurality of isolated reaction sites containing one or more biological samples. The temperature controller is configured to maintain or control a temperature of at least one of the support, the case, or the one or more biological samples during an assay or reaction on the one or more biological samples. The support is also configured to maintain at least one of the surfaces of substrate at a positive angle relative to a horizontal plane during the assay or reaction.
US10994273B2 Actuation of parallel microfluidic arrays
An improved actuator for use in a microfluidic particle sorting system utilizes a staggered packing scheme for a plurality of actuators used to selectively deflect a particle in an associated sorting channel from a stream of channels. An actuator block may be provided for housing a two-dimensional array of actuators, each configured to align with an actuation port in an associated sorting chip containing a plurality of sorting channels. The actuator block may include a built-in stressing means to pre-stress each actuator housed by the block. An actuator comprising a piezo-electric stack may employ contact-based electrical connection rather than soldered wires to improve packing density. The actuator may be an external actuator. That is, the external actuator is external to the substrate in which the sorting channels are formed.
US10994269B2 Method and apparatus for coating a carrier
Disclosed is a method and a corresponding apparatus for coating open-pored bodies with at least one coating suspension, the coating suspension having solids and solutes in a liquid medium in a quantity in wet state which is to correspond to at least a required target quantity, and the coating operation having a variation in the applied wet coating quantity from one body to the other. The method includes steps of: coating the body with an actual quantity of the coating suspension, which is always larger than the required target quantity taking the variation of the coating operation into account, determining the difference between the actual quantity and the required target quantity, and reducing the difference between actual quantity and target quantity by removing still wet coating suspension.
US10994266B2 Process for making modified small-crystal mordenite, transalkylation process using same, and modified small-crystal mordenite
A modified UZM-14 zeolite is described. The modified UZM-14 zeolite has a Modification Factor of 6 or more. The modified UZM-14 zeolite may have one or more of: a Si/Al2 ratio of 14 to 30; a total pore volume in a range of 0.5 to 1.0 cc/g; at least 5% of a total pore volume being mesopores having a diameter of 10 nm of less; a cumulative pore volume of micropores and mesopores having a diameter of 100 Å or less of 0.25 cc/g or more; or a Collidine IR Bronsted acid site distribution greater than or equal to an area of 3/mg for a peak in a range of 1575 to 1700 cm−1 after desorption at 150° C. Processes of making the modified UZM-14 zeolite and transalkylation processes using the modified UZM-14 zeolite are also described.
US10994263B2 Polarized fiber mats for catalyst support structures
A polymer-catalyst assembly includes polarized polymeric nanofibers retaining a plurality of catalytic metallic nanoparticles. A method of making the polarized polymer-catalyst assembly may include providing a fiber mat having polymeric nanofibers retaining a plurality of catalytic metallic nanoparticles, stretching the fiber mat in a uniaxial direction, simultaneous with the step of stretching, thermally heating the fiber mat, simultaneous with the steps of stretching and thermally heating, subjecting the fiber mat to an electric field, whereby the simultaneous steps of stretching, thermally heating, and subjecting thereby form a polarized fiber mat.
US10994262B2 Catalyst for oxidative dehydrogenation and method of preparing the same
Disclosed are a catalyst for oxidative dehydrogenation and a method of preparing the same. More particularly, a catalyst for oxidative dehydrogenation of butene having a high butene conversion rate and superior side reaction inhibition effect and thus having high reactivity and high selectivity for a product by preparing metal oxide nanoparticles and then fixing the prepared metal oxide nanoparticles to a support, and a method of preparing the same are provided.
US10994260B2 Superabsorbent polymeric structures
Provided herein is a superabsorbent polyHIPE composition-of-matter comprising a majority of ionizable pendant groups, capable of absorbing up to 300-fold by mass water while exhibiting a notable mechanical strength in both the dry and wet form, as well as various uses thereof.
US10994259B2 Metal-organic frameworks for the adsorption and catalytic transformations of carbon dioxide
Novel crystalline porous materials known as metal-organic frameworks (MOFs) and methods for their synthesis are provided herein. The MOFs include a M6(μ3-OH)8(OH)8(μ2,η2-(O2C)2cyclam)8 cluster, and a metal atom coordinated to the one or more cyclam of the cluster, wherein M is Zr or Hf, and the metal atom is any one of Cu, Ni, Cr, Ru, Co, and Gd. The MOFs can be used as an adsorbent, alone or in a medium with other components, of CO2. The MOFs can also be used as a catalyst for the transformation of CO2 and epoxides to cyclic carbonates. The MOFs can also be used in the electrochemical catalytic reduction of CO2. The MOFs can also be used for photocatalytic CO2 reduction for the production of carbon-based fossil fuels. The MOFs can also be used for light-induced nitric oxide (NO) release. The MOFs can also be used as magnetic resonance imaging (MRI) agents.
US10994257B1 Extraction of target materials using CZTS sorbent
Various embodiments disclosed relate to extraction of target materials using a CZTS sorbent. A method of extracting a target material from a medium includes contacting a copper zinc tin sulfur (CZTS) sorbent with the target material in the medium including the target material to form a used CZTS sorbent that includes the target material.
US10994256B2 High-throughput combinatorial materials experimental apparatus for in-situ synthesis and real-time characterization and related methods
A high-throughput combinatorial materials experimental apparatus for in-situ synthesis and real-time characterization includes a composition spread device to prepare continuous or discrete composition distribution as precursor of the high-throughput experimental samples library, a low temperature diffusion mixing device to thoroughly mix the composition spread in the thickness direction through diffusion at a relatively low temperature to form an amorphous precursor, and an integrated synthesis-characterization unit for heat treatment of the material library precursor in either a parallel or point-by-point scanning mode at different thermodynamic conditions for phase formation and to characterize features or properties of the materials of interest in an in-situ and real-time manner. The integrated synthesis-characterization unit includes a chamber maintained at desired vacuum and atmosphere, a micro-heating source, an excitation source, a signal collector, and a sample holder.
US10994254B2 System, device, and method for controlling mass flow of a catalytically reactive gas in a mixed gas stream
Provided herein are methods, systems, and apparatus for measuring and/or controlling mass flow/concentration of a catalytically reactive gas within a mixed gas stream by determining thermal rise due to decomposition.
US10994253B2 Device for expelling drops of a flowable product, and method for operating one such device
An apparatus for dropletizing a flowable product, having an outer tube which is arranged in a rotatable manner on a core, wherein, in the core, a feed device for the product to be dropletized and a distribution apparatus bearing against the inner circumference of the outer tube are provided. A device for cleaning an outer circumference of the outer tube is provided, wherein the device has a cleaning spatula, a guide rail for the cleaning spatula, which guide rail extends parallel to a central longitudinal axis of the outer tube, and a first drive for moving the cleaning spatula along the guide rail.
US10994244B2 Apparatus and method for waste gas scrubbing
A device for waste gas scrubbing in a urea plant may be configured such that a waste gas passes along a transportation direction in the duct. The duct may include a first region for removing urea dust particles from the waste gas and a second region for removing chemical compounds from the waste gas, which can be integrated by an acid-base reaction into an aqueous liquid phase. A cross-sectional area of the duct extending perpendicular to the transportation direction in the second region may be greater than a cross-sectional area extending perpendicular to the transportation direction in the first region. Further, the device may be configured such that the duct extends horizontally at least in sections and/or the transportation direction of the waste gas through the duct extends horizontally in an installed state.
US10994241B1 Sorbent system for removing ammonia and organic compounds from a gaseous environment
A first process and sorbent for removing ammonia from a gaseous environment, the sorbent comprised of graphene oxide having supported thereon at least one compound selected from metal salts, metal oxides and acids, each of which is capable of adsorbing ammonia. A second process and sorbent system for removing ammonia and a volatile organic compound from a gaseous environment; the sorbent system comprised of two graphene-based materials: (a) the aforementioned graphene oxide, and (b) a nitrogen and oxygen-functionalized graphene. The sorbents are regenerable under a pressure gradient with little or no application of heat. The processes are operable through multiple adsorption-desorption cycles and are applicable to purifying and revitalizing air contaminated with ammonia and organic compounds as may be found in spacesuits, aerospace cabins, underwater vehicles, and other confined-entry environments.
US10994231B2 Water filter
A filter includes a filter assembly deployed within a pressure vessel. The filter includes a series of filter configurations arranged along a central flow path connected to an outlet. Each filter configuration has filter screens overlying at least one filtrate channel which directs filtered fluid to the central flow path, A partition is deployed within the pressure vessel so as to subdivide the pressure vessel into a first filter chamber and a second filter chamber, each containing a number of the filter assemblies. A flow diverter is deployed in the central flow path for diverting a flow of filtered liquid passing along the central flow path from the first filter chamber so as to flow outwards from the central flow path to undergo a second filtering in the second filter chamber. Also disclosed is an outlet flow throttling arrangement to avoid overload of a backwash cleaning system.
US10994229B1 Water filtration system
A filter assembly includes an inlet end, a sediment filter having a sediment filter surface facing the inlet end and cylindrical filters. The sediment filter surface is orthogonal to each cylindrical filter surface. A first channel and a second channel may fluidly connect the sediment filter to the more cylindrical filters. The first channel can have a central axis that is orthogonal to a central axis to the more than one cylindrical filter. A central axis of the second channel may be in a direction along the length of the more than one cylindrical filter.
US10994226B2 Fuel deoxygenation with a spiral contactor
Provided are techniques that include operating a spiral contactor. The techniques include receiving, by a spiral contactor, a first fluid, and receiving a second fluid, wherein the first fluid is different than the second fluid. The techniques also include exchanging the first fluid and the second fluid using the spiral contactor, and outputting a deoxygenated fluid from the spiral contactor, wherein the deoxygenated fluid has a lower oxygen concentration than the first fluid.
US10994225B2 Tank for holding contents which can separate into different phases
Tank for holding contents which can separate into different phases, said tank comprising at least two outlet pipes each provided through a bottom of the tank with a first end of the outlet pipes provided outside the tank and a second end provided inside the tank, the second ends of the at least two outlet pipes being provided at different heights within the tank.
US10994224B2 Fractionator annular drain apparatus and method
A tank system may be conventional and fixed, or mobile, such as a fracking fluid or other tank trailer. A drain port thereof is fitted with an adapter connecting a snorkel system to drain liquids from near the top of the liquid level in the tank. A snorkel head at the extreme distal end of a tube near the longitudinal center of the tank is suspended by a system of buoys. A flow field controller plate resists formation of vortices near the snorkel head, so it can operate as near the surface as possible, withdrawing the highest grade oil efficiently. At its exit, the proximal end of the tube drains oil through an inner conduit of an adapter at a penetration in the wall of the tank. The adapter forms an annulus around the inner conduit draining tank bottoms directly from the tank.
US10994222B2 Pre-heater assembly with moderately thermally conductive capillary surrounding
A pre-heater assembly for pre-heating a fluid, in particular in a fluid separation apparatus, wherein the pre-heater assembly comprises a capillary having a lumen and being configured for conducting the fluid, and a thermal coupling body contacting at least part of the capillary, having a value of thermal conductivity in a range between 8 W/(m K) and 100 W/(m K) and being arrangable so that heat generated by a heat source is supplied to the capillary via at least part of the thermal coupling body.
US10994221B2 System and method for extracting hydrocarbons
A system and method for extracting hydrocarbons utilizing recirculated washing medium to enhance efficiency. Some embodiments include a helical agitation member configured to promote extended contact between material containing hydrocarbons and a washing medium.
US10994217B2 Latex balloon with metalized mirrored finishing
The present disclosure refers to a latex balloon with a particular finishing as its surface is highly reflective, and with metallized tones. The balloon of the present disclosure is manufactured in at least two layers. The instant disclosure provides a balloon with metallized mirrored finishing which may also be added with several colors. Additionally, the reflective power of the balloon surface is enhanced. In addition, methods for manufacturing the present balloon are provided.
US10994210B1 Mobile game using image extraction
The present invention is a system and method for providing an online game implemented by means of a computer system. The method includes the step of storing a plurality of images in at least one computing device. The method then includes the step of obtaining content data from the plurality of images stored in the computing device through a content extraction module. The method includes the step of facilitating the users to initiate a challenge for each other to create a game session over a game networking system through a challenge creation module. The game session includes a friend game session and a date game session. The method includes the step of initiating the game session created by the challenge creation module over the game networking system through a gaming module.
US10994208B2 Information processing system, storage medium storing information processing program, and information processing method
An example of an information processing system includes a training apparatus and an information processing apparatus. The information processing apparatus executes a game. The training apparatus includes a sensor and a processor. The sensor detects a load applied on the training apparatus. The processor transmits information relating to the load detected by the sensor as first information to the information processing apparatus while the game is executed. The processor stores information relating to the load detected by the sensor as second information in a storage device integral with or separate from the training apparatus while the game is not executed. The information processing apparatus progresses the game based on the first information received from the training apparatus, and gives a reward that has an influence on the progress of the game to a user of the game based on the second information obtained from the storage device.
US10994195B2 System and method for video game user registration based on game progress
A control method performed by a computer including a storage module and configured to control progress of a game played by a user registered in an application, includes storing, in the storage module, identification information of each of a plurality of users in association with registration information indicating whether the user is registered in the application, retrieving a game progress request including identification information of a first user from a first terminal device of the first user, determining whether or not the first user is registered in the application, transmitting display data for displaying a game screen used in the game to the first terminal device when the first user is registered in the application, and transmitting display data for displaying a registration screen for registering the first user in the application to the first terminal device, when the first user is not registered in the application.
US10994194B2 Processing apparatus and projection image generation method
A picked up image acquisition unit acquires a picked up image obtained by picking up an image of a region including a projection region projected by a projector. A recognition processing unit executes a recognition process of a card included in the picked up image. A projection image generation unit generates a projection image to be projected by the projector on the basis of the card recognized by the recognition processing unit. An instruction detection unit detects an instruction for the card. The recognition processing unit detects an object different from the card and provides detection information of the detected object to the instruction detection unit. The instruction detection unit then detects an instruction for the card from the detection information of the object provided thereto. The projection image generation unit generates a projection image on the basis of the instruction for the card.
US10994192B2 System and method for presenting a game of chance with a progressive jackpot
A gaming machine receives a first play input at a first gaming machine, determines a first quantity of play areas based on a first wager, generates at least one first play area based on the determined first quantity, and determines whether the at least one first play area satisfies a predetermined first threshold. At least a portion of the first wager associated with the first play input is allocated to a progressive jackpot. At least a first portion of the progressive jackpot is allocated to the first gaming machine when the at least one first play area satisfies the predetermined first threshold.
US10994189B2 Glove structure
The purpose of the present invention is to provide a ball glove structure that improves glove functionality for a player of baseball or softball even through provided with a box-like protective thumb-slot. The ball glove generally comprises an outer shell where the shell part Is formed by sewing together a ball catching palm surface part (1) and a backing surface part (2) provided with thumb and finger stalls or slots with a lace (3). The inventive glove structure comprises (A) a box-like thumb protective stall or slot (21) provided with a hem spread opening (21e) having an enlarged angle (α) at the bottom portion with regard to the center line of the thumb slot for easy movement of the thumb bottom at the time of opening/closing of the glove and also (B) a fixing structure comprising a pair of slits (10a, 10a) for dividing a hand opening band (5) into two parts; one is a thumb side and the other is a little finger side and a pair of straps (11a,11b) for fixing the bottom of the index finger to make a secure movement axis for opening/closing the glove as well as fastening the divided hand opening band for preventing the glove hand from slipping out from the hand opening band. Preferably, the little finger is fixed by the adjustable strap structure (23) to fix the little finger.
US10994183B1 Golf swing training device and method of use
A golf swing training device and method of use is provided. The golf swing training device has an elongated member with a first end disposed opposite a second end. The first end includes a slot which is sized to receive a shaft of a golf club. The slot is disposed at a diagonal angle relative to the elongated member such that the shaft of the golf club passes through the elongated member. A curled member is disposed at the second end which can wrap around a shoulder of a user. In use, the golf training aid provides tactile feedback to a user as they execute a golf swing and aids in training the user to keep their arms in a proper position throughout a backswing and a golf swing motion.
US10994182B1 Sports training machine
A basketball training apparatus includes a shot completion sensor, a condition sensor, and a computer. The shot completion sensor determines whether a shot goes through a basketball hoop. The condition sensor senses a physical condition of a basketball shooter. The computer is in communication with the shot completion sensor and the condition sensor, and has a processor for calculating shot completion percentage as a function of the physical condition.
US10994176B2 Grooves of golf club heads and methods to manufacture grooves of golf club heads
Embodiments of grooves of golf club heads and methods to manufacture grooves of golf club heads are generally described herein. Other embodiments may be described and claimed.
US10994174B2 Resin composition for golf balls, and golf ball
A resin composition for golf balls is made of (A) polyurethane or polyurea and (B) a styrene resin material, component (B) being included in an amount of 0.5 to 50 parts by weight per 100 parts by weight of component (A). In a golf ball having a core and a cover of one or more layer encasing the core, at least one cover layer is formed of this resin composition. The resin composition is especially useful as a golf ball cover material because the ball does not fly too far and is easier to control on approach shots, yet does not sacrifice distance on shots with a driver.
US10994173B2 Weight platform treadmill
A treadmill includes a deck, a first pulley disposed in a first portion of the deck, a second pulley disposed in a second portion of the deck, a tread belt surrounding the first pulley and the second pulley, and a platform incorporated into the deck.
US10994169B2 Method of resistance training utilizing eddy current resistance
A method of utilizing eddy currents to induce resistance that simulates and replaces physical weights in strength training exercise equipment includes a user moving at least one of a first member and a second member that supports magnets of alternating polarity, relative to each other bi-directionally. The bi-directional movement can be linear, radial, arcuate, or circular. The movement of the first member and a second member relative to each other induces in the first member eddy currents which resist the movement of the first member, the second member, or both bi-directionally.
US10994167B1 Swinging and climbing apparatus with vertically supported parallel webbing
A vertically supported swinging and climbing apparatus has two parallel sections of elongated webbing is a structure. The apparatus comprises pads secured around vertical supports. An elongated webbing wrapped around the pads on the vertical supports. The elongated webbing is configured with two parallel straight portion. Webbing couplings are attached to the straight portions of the elongated webbing to support swinging and climbing attachments.
US10994166B2 Transition trampoline bed
A transition trampoline apparatus includes a transition trampoline bed having an elongate configuration that, when mounted on support legs, provides a track for a gymnast that is sufficiently bouncy to ease wear and tear on a gymnast's knees and ankles while not affecting her footwork while running and doing gymnastic maneuvers.
US10994164B2 Fire apparatus vehicle with high-flow articulated water tower
A relatively small fire apparatus vehicle, which may have a single rear axle, is provided that includes a high-flow articulated water tower that delivers water at a rate of up to 1500 GPM (gallons per minute). The high-flow articulated water tower includes a water splitter that divides a water flow from a pump system into a pair of water flow path segments delivered through a pair of lower tower arm water pipes. The water flow path segments may be recombined in a water stem knuckle at a joint between the lower tower arm and an upper tower arm of the articulated water tower that is delivered as a combined flow through an upper tower arm water pipe and out a delivery nozzle.
US10994161B2 Release device for use with a fall protection unit having a deployable lifeline
A release device (10) is provided for use with a fall protection unit (12) having a lifeline (14) that can be deployed N in a fall direction to protect a worker (16) in a fall event, and includes a frame (22) configured to fix the release device (10) to a fall protection unit (12), a release member (24) mounted for movement from a lock position to a release position, a connection member (26) configured to connect the deployable lifeline (14) of the fall protection unit (12) to another piece of fall protection equipment connected to the worker (16), the connection member (26) having a locked condition wherein the connection member (26) is prevented from moving in a fall direction relative to the frame (22) and a released condition wherein the connection member (26) is free to move in the fall direction relative to the frame (22); the connection member (26) having a stop surface (34); and a stop link (28) mounted to the frame (22) to move from a engaged position to a disengaged position in response to the release member (24) moving from the lock position to the release position. The stop link (28) has a hold surface (38) engaged with the stop surface (34) with the stop link (28) in the engaged position and the connection member (26) in the locked condition, and at least one of the stop surface (34) and the hold surface (38) area planar surface extending at an acute angle to the fall direction with the connection member (26) in the locked condition and the stop link (28) in the engaged position.
US10994159B2 Harness for breathing apparatus
There is disclosed a harness for breathing apparatus comprising a structural support member for supporting a vessel of breathable gas, a waist belt, and a pivot joint mechanism coupling the structural support member to the waist belt. The pivot joint mechanism comprises a release part which is movable to decouple the structural support member from the waist belt.
US10994153B2 Apparatus, method, and system for selectively effecting and/or killing bacteria
Certain exemplary embodiments of the present disclosure can provide an apparatus and method for generating at least one radiation can be provided. The exemplary apparatus and/or method can selectively kill and/or affect at least one bacteria. For example, a radiation source first arrangement can be provided which is configured to generate at least one radiation having one or more wavelengths provided in a range of about 190 nanometers (nm) to about 230 nm, and at least one second arrangement can be provided which is configured to prevent the at least one radiation from having any wavelength that is outside of the range can be provided.
US10994152B2 Dermatological treatment apparatus
The present invention relates to a dermatological treatment apparatus. Such dermatological treatments include but are not limited to hair removal, treatment of acne and lesions and also skin rejuvenation. The apparatus comprises a housing; a light emitting source provided in the housing arranged to emit light energy along an energy pathway to external of the device; and a filter arrangement positioned in the energy pathway having at least a first and a second light energy filtering portion together combining to span across the energy pathway for filtering the light energy passing to external of the device.
US10994150B2 Radiation apparatus for the radiation of human skin
A radiation device is for the radiation of human skin, preferably the face of a user, in particular at least with radiation in the red light range, with a source of radiation and a filtering device for filtering the radiation emitted by the source of radiation. The filtering device is configured in such a way that the radiation device emits radiation in a wavelength range from 280 to 400 nm and beyond that radiation in a wavelength range of 600 to 700 nm, and that the radiation device emits at least zonally radiation in a wavelength range of a visible color shade of the visible light spectrum and filters further radiation of the visible light spectrum.
US10994149B2 Wireless implantable power receiver system and methods
A method and system is presented for an implantable wireless power receiver for use with a medical stimulation or monitoring device. The receiver receives transmitted energy through one or more non-inductive antenna(s), utilizes microelectronics to perform rectification of the received signal for generation of a DC power supply to power an implantable device, and may also utilize microelectronics to provide parameter settings to the device, or stimulating or other waveforms to a tissue.
US10994144B1 Systems and methods for improved spinal cord stimulation
Stimulation treatments for various medical disorders, such as neurological disorders, comprise novel systems, strategies, and methods for providing TMS, electrical, magnetic, optical and other stimulation modalities. Some stimulation methods comprise varying the stimulation parameters to improve the therapeutic efficacy of stimulation and decrease risk of habituation and side-effects such as interference with normal brain, sensory, motor, and cognitive processes. The creation, and subsequent variation, of stimulation parameters can use sensed data in order to match, adjust, or avoid matching characteristics of the stimulation therapy relative to certain endogenous brain activities. Novel methods are described for choosing, creating and subsequently stimulating with partial signals which summate to produce therapeutic vector fields having unique temporal patterns and low- or high-frequency spectral content. Improvements for the treatment of pain are disclosed.
US10994141B2 Adaptive cognitive prosthetic and applications thereof
An adaptive cognitive prosthetic that learns to replace neural function that was lost due to a brain injury or disease is described herein. In some embodiments, an adaptive cognitive prosthetic comprises a processing unit for converting input data from an input assembly into a cognitive variable and selecting a stimulation pattern for conveying the cognitive variable. The processing unit employs an adaptive algorithm to assemble the stimulation pattern by combination of subset stimulation patterns, the combination of subset stimulation patterns learned by the adaptive algorithm through error analysis.
US10994140B2 Devices, systems, and methods for stimulation therapy
Generally discussed herein are systems, devices, and methods for providing a therapy (e.g., stimulation) and/or data signal using an implantable device. Systems, devices and methods for interacting with (e.g., communicating with, receiving power from) an external device are also provided. A system can include an external power source that propagates a field within tissue and an at least partially implantable device configured to receive the propagated field from the external power source, the implantable device including circuitry, a first antenna electrically coupled to the circuitry, a second antenna electrically coupled to the first antenna, and an electrode electrically connected to the circuitry.
US10994135B2 Treatment of headaches by electrical stimulation
A system is provided that includes a patch, which includes a plurality of electrodes and is configured to be coupled to a subject; and a mobile device, including a computer processor configured to: obtain a physical location of the subject; obtain, from a remote service, a migraine-related forecast specific to the physical location of the subject; enrich the migraine-related forecast with treatment-related statistics collected from a plurality of other subjects to whom electrostimulation treatment has been applied; present the migraine-related forecast on the mobile device; receive an input from a subject; and in response to the input, while the patch is coupled to the subject, wirelessly communicate a control signal that causes the electrodes to apply stimulation to the subject. Other embodiments are also described.
US10994132B1 Wearable, unsupervised transcranial direct current stimulation (tDCS) device for movement disorder or memory therapy
The present invention relates to a system and methods for noninvasively providing therapy for movement disorder symptoms. The present invention provides such a therapy system which provides trans-cranial direct current stimulation (tDCS) in order to treat those symptoms and the disorders. The present invention further provides such tDCS therapy while the subject sleeps in order to minimize the time required and impact of the therapy on the subject's waking life. The system, methods, and devices of the present invention are intended to provide a low-dose electrical current, trans-cranially, to a specific area of the subject's brain while he or she sleeps in order to decrease the occurrence, severity, and duration of the symptoms of movement disorders. The present invention aims to reduce the amount of medication necessary, counteract the effects of medication wearing off during sleep, and to overall improve the quality of life of subjects suffering from movement disorders.
US10994130B2 Devices and methods for repairing damage to a nerve
An example device for repairing a nerve is described herein. The device can include a flexible carrier layer made of a biologic material, and a metallic support member including a plurality of micro-protrusions extending therefrom. The metallic support member can be at least partially integrated with the flexible carrier layer. Additionally, the flexible carrier layer can be configured to cover at least a portion of the nerve, and the micro-protrusions can be configured to attach to a superficial tissue of the nerve.
US10994126B2 Hearing percept parameter adjustment strategy for a hearing prosthesis
A prosthetic system, comprising a first sub-system configured to evoke a hearing percept based on a first principle of operation, and a second sub-system configured to evoke a hearing percept based on at least one of the first principle of operation or a second principle of operation different from the first principle of operation, wherein the first and second sub-systems are configured to independently process respective inputs indicative of an ambient sound to harmonize an estimated recipient perception of magnitude of a property of the respective evoked hearing percepts.
US10994122B2 Electrical stimulation device
An electrical stimulation device is provided. According to one embodiment of the present invention, the electrical stimulation device for applying an electrical stimulation to the skin of a user comprises: a patch layer, which is a single patch layer and makes contact with the skin of the user when the electrical stimulation device is worn by or attached to the user; and a plurality of patch segments formed to be spaced apart from each other on the patch layer and transmitting current to the patch layer.
US10994121B2 Carbon nanotube composite electrode using vacuum suction
A Carbon NanoTube (CNT) composite electrode includes a lower electrode having a through-hole formed therein, and configured to be attached to the skin of a subject body to detect a biosignal, an upper electrode provided on one surface of the lower electrode to form an enclosed space between the lower electrode and the upper electrode, and configured to receive the biosignal detected by the lower electrode, and an air discharge portion formed in at least one of the lower electrode and the upper electrode, and discharging air present in the enclosed space and the through-hole externally so as to be configured to allow the upper electrode and the lower electrode to be attached to the skin of the subject body via vacuum suction.
US10994117B2 Multi-cap for connecting catheter
Provided is a multi-cap for connecting a catheter and the multi-cap includes: a body having an internal hole formed in a longitudinal direction and having an end connected to a catheter; a cover portion disposed on an outer side of the body in the longitudinal direction of the body and spaced from the body such that the catheter is partially inserted between the outer side of the body and the cover portion. Further, a spout is formed at a second end of the body to transmit an injection substance from the outside to the hole and a capping part is connected to a side of the body to selectively close the inlet of the spout.
US10994114B2 Integrated sliding seal fluid pathway connection and drug containers for drug delivery pumps
A fluid pathway connection includes a piercing member, a connection hub, and a sliding pierceable seal, wherein the sliding pierceable seal is configured to move from a first position, where the piercing member is initially retained within a sterile cavity between the connection hub and the sliding pierceable seal, to a second position, where the pierceable seal has been penetrated by the piercing member. A filter may be utilized to enclose the sterile cavity from the outside environment. The fluid pathway connection may further be configured to move to a third position where one or more interconnects and/or one or more corresponding contacts are permitted to transmit a signal to the user. Such fluid pathway connections may be integrated into a drug container having a barrel and a plunger seal. A drug delivery pump includes such integrated fluid pathway connections and drug containers.
US10994112B2 Drug delivery system with electromagnetic field generator
A drug delivery device (100) includes a base (102) having a first region (104) with a drug delivery assembly (106) associated therewith. The drug delivery device also includes an antenna (112) disposed in the first region to radiate an electromagnetic field, the base defining a plane (114) and the antenna disposed in the plane of the base, and an electromagnetic field generator (116) selectively coupled to the antenna.
US10994110B2 Apparatus and methods for delivering therapeutic agents
The present embodiments provide apparatus and methods suitable for delivering a therapeutic agent to a target site. The apparatus generally comprises at least one container for holding a therapeutic agent, and a pressure source for facilitating delivery of the therapeutic agent. In one embodiment, the pressure source may be placed in selective fluid communication with a proximal region of the container and fluid from the pressure source may flow through at least a portion of the container to urge the therapeutic agent through container towards the target site. In an alternative embodiment, the container and the pressure source may be coupled to first and second inlet ports of a connecting member, respectively, such that the therapeutic agent flows through an outlet port of the connecting member and towards the target site.
US10994108B2 Programmable drainage valve with fixed reference magnet for determining direction of flow operable with analog or digital compass toolsets
A method for using an implantable programmable bodily fluid drainage valve including a fixed reference magnet and an adjustable valve unit having a pair of primary magnetic elements. In accordance with the present inventive method the implantable programmable bodily fluid drainage valve is operable using either an intended toolset including a sensor array for detecting a magnetic field or a non-intended toolset employing an analog type compass assembly instead of the sensor array, wherein a location of the fixed reference magnet in the implantable programmable bodily fluid drainage valve and size of the fixed reference magnet has substantially no negative influence on operation of the analog type compass assembly of the non-intended toolset when used to operate the implantable programmable bodily fluid drainage valve.
US10994100B2 Sheath retainer devices, systems and methods
In general, medical sheath systems that can employ retainer devices having a plurality of channels configured to retain a sheath assembly in one or more curved configurations are described. In one embodiment, a retainer device may releasably retain a curvable tube of the sheath assembly in any of multiple curved configurations that range, for example, in selectable increments between 0° to 180°.
US10994098B2 Medical device including an actuator restraining assembly
The present disclosure provides a means of holding, securing, or self-locking an actuating mechanism, such as a plunger-type or slide-type actuating mechanism, on a medical device having a deflected distal region using pinch points without the need for a secondary restraining or locking mechanism within the medical device. The present disclosure also provides a means to reduce the force experienced by a user during the deflection of a medical device such that use fatigue is lessened or eliminated. Various embodiments of the present disclosure are set forth herein.
US10994096B2 Balloon catheter with floating hub
A balloon catheter for use with a guidewire includes an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is connected to the distal end of the shaft, the balloon including a working surface. A radiopaque identifier is provided for identifying the working surface. A receiver adjacent the proximal end of the shaft is adapted for allowing the shaft to move relative to the receiver in at least the longitudinal direction.
US10994092B2 System and method for adjusting the intensity of sensory stimulation during sleep based on sleep depth
The present disclosure pertains to a system configured to adjust an intensity of sensory stimulation delivered to a subject during a sleep session based on sleep depth in the subject during the sleep session. The restorative value of sleep may be increased by enhancing sleep slow-waves using sensory stimulation. The stimulation may be applied at an appropriate timing and/or intensity to enhance sleep slow-waves to enhance slow-waves without disturbing sleep.
US10994091B2 Adsorbent cartridge with accurate visual indicator
A cartridge comprising layers of adsorbent sheet is described. The cartridge includes an indicator that characterizes the consumption state of the adsorbent within the cartridge. The indicator is applied in a way such that discrete areas of indicator are visible. These discontinuous areas of indicator may be applied to the outside surface of the cartridge. Alternatively, the discontinuous areas may be formed by cutting windows in the outermost layer of the cartridge and either coating indicator on the layer beneath the window, placing an indicator layer between the window and the layer beneath it or filling the window with an indicating plug of material so that the indicator is visible from the outside of the cartridge. The indicator layer and indicator plug embodiments allow the use of any indicator with any adsorbent.
US10994090B2 Patient interfaces
An interface for positive pressure respiratory therapy includes a mask assembly having a mask seal and a mask shell. The mask assembly is positioned lower than and exposes a bridge of the user's nose. The mask seal includes portions that contact opposing sides of the user's nose. Each portion of the mask seal includes supports that help maintain the mask seal's shape. Two covers can be supported relative to the mask assembly and adjacent a respective portion of the mask seal. The covers limit expansion of the portions of the mask seal in response to pressurized air within the mask seal. The supports can transfer load from the mask seal to the covers. An interface system can include multiple size mask seals, which can be designed with consideration of ethnic variations in nose size and/or shape.
US10994089B2 Bridle delivery system, method, and apparatus for securing nasal tubes
Systems, methods, and apparatus for securing nasal tubes are disclosed. An exemplary system includes a bridle, a magnetic portion connected to the bridle, a delivery probe, a retrieval probe, and a clamp. The delivery probe includes an elongated member having proximal and distal ends, the distal end configured to deliver the magnetic portion, and a bridle lock configured to release the bridle upon actuation of an actuator. The retrieval probe includes an elongated member having proximal and distal ends, the distal end including a magnetic portion configured to magnetically couple with the other magnetic portion, and a magnetic coupling indicator configured to provide an indication in response to a magnetic coupling. The clamp includes a channel portion with an inside diameter larger than an outside diameter of a nasal tube. The clamp is configured to secure the nasal tube following placement of the bridle by the delivery and retrieval probes.
US10994084B2 Substance inhalation system and method
A stand-alone chamber or multi-chamber inhalation system has at least two alternative vaporized test liquid supply systems for passive or self-administered delivery of vaporized test fluid and air to one or more test chambers, which can be passive or restraint chambers, based on operator selection of delivery on and off times in a passive mode or actuation of an actuator in the chamber by a test animal in a self-administered mode. In one case, a multiple inhalation chamber system has two or more separate test fluid delivery systems and provides options for selective passive uniform drug delivery to multiple chambers or selective delivery of two or more different drugs to different groups of chambers from different delivery systems so that two different drugs or different concentrations of delivered drugs can be tested simultaneously.
US10994083B1 Electronic inhaler
An electronic inhaler having an embedded system and a method for precise and repeatable delivery of multiple types of medications in different forms to the pulmonary system of a human user. The inhaler can include a housing defining an internal chamber for accommodating at least two cartridges (reservoirs) containing multiple medicines in different states, and a meter reservoir compartments that can automatically provide precise doses of medicine using vacuum pressure sensors. The sensors can be in communication with the internal embedded system/electronics (microcontroller) of the inhaler and the electronics/microcontroller can be in permanent communication with a software application running on the user's smart phone or other electronic device.
US10994080B2 Autoinjector with retracting needle
An automatic drug delivery device is described, comprising: a housing (1); a skin sensor element (15) coupled to the housing and movable relative to the housing, wherein the skin sensor element is biased into a front position relative to the housing and is movable to a rear position relative to the housing when the skin sensor element is pressed against an injection site; a needle assembly comprising a hypodermic needle (11), the hypodermic needle extending outside of the housing when the device is in a needle insertion configuration; a drug delivery mechanism comprising a stored energy source (4), within the housing; wherein the drug delivery mechanism is released when the skin sensor element is moved from the front position towards the rear position and wherein the stored energy source is arranged to expand along an axis that is offset from an axis of travel of the needle assembly in use; a needle retraction mechanism configured to withdraw the hypodermic needle into the housing when the needle retraction mechanism is released; wherein the needle retraction mechanism is coupled to the skin sensor element such that when the skin sensor element is moved from the rear position towards the front position, and the needle is in the needle insertion position, the needle retraction mechanism is released.
US10994079B2 Semiautomatic syringe with improved safety
The present invention provides a semiautomatic syringe with improved safety including: a main body; a receptacle which is installed at one side of the main body, receives therein a set amount of infusion solution, and has a set pressure; an infusion solution tube which extends by a set length while penetrating the main body, connects with the receptacle, and provides a passageway for moving the infusion solution; a protective cover which is installed at the other side of the main body, connects with the infusion solution tube, extends by a set length, and has a hollow portion; an injection needle which is provided in the protective cover and has an injection hole formed to discharge the infusion solution, which moves through the infusion solution tube, to the outside; and a flow rate adjusting member which is installed in the main body and adjusts a movement amount of the infusion solution by opening and closing the passageway of the infusion solution tube, in which the injection needle is provided in a state of being inserted into the hollow portion of the protective cover, and a part of the injection needle protrudes to the outside of the protective cover by a change in pressure in the receptacle when the passageway of the infusion solution tube is opened, thereby achieving a more convenient, economic, and safe usage.
US10994077B2 Enhanced confirmations for touchscreen infusion pump
Enhanced confirmations for programming of touchscreen infusion pumps reduce the likelihood of users confirming pump parameters that have been mistakenly programmed. Following programming of a given pump parameter, an icon or image intuitively related to the pump parameter can be displayed on the touchscreen. To confirm programming of the parameter, the user can be required to trace the icon on the touchscreen. The user will therefore necessarily associate the confirmation step with the parameter being programmed and be far more likely to realize if a mistake has been made because the user was intending to program a different parameter than with simple confirmations involving the press of a confirmation button.
US10994072B2 Infusion system configurations
Infusion system configurations and assemblies facilitate routing of infusion circuit tubing lines. Tubing lines are routed into and out from compartments of a shielding assembly for the infusion system, at locations which prevent kinking and/or crushing of the lines, and/or provide for ease in assembling the circuit. A plurality of the lines may be held together by a support frame to form a disposable infusion circuit subassembly, that can further facilitate routing of the lines.
US10994067B2 Method and apparatus for machine error detection by combining multiple sensor inputs
A system associated with a medical treatment device for detecting a condition of a patient includes an input device including at least a camera or a microphone. The system also includes a medical treatment device with a controller/classifier and at least one of flow controller, a pump, and/or an alarm output. The controller/classifier has at least a video-image processor or an audio processor configured to recognize a face and a body or to recognize changes in skin color, facial expression, or body position. The controller/classifier may also recognize speech and classify predefined normal and irregular sound patterns, and output state data corresponding thereto. The controller/classifier is connected to apply the state data to the at least one flow controller, pump, and/or alarm output.
US10994066B2 Infusion line with a facility to promote mixing of an infusion solution with a further fluid, apparatuses and method
The present disclosure relates to an addition line for adding an infusion solution to a fluid, which flows in an extracorporeal blood circuit, wherein the addition line comprises a pressure release valve or a check valve. It further relates to an extracorporeal blood circuit, a blood treatment apparatus and a method using the addition line.
US10994065B2 Apparatus for carrying out an extracorporeal blood treatment and method for adding a substitution fluid
The invention relates to an apparatus for carrying out an extracorporeal blood treatment in which a substitution fluid is administered to the patient, wherein the apparatus comprises an extracorporeal blood circuit and a substitution line opening into the extracorporeal blood circuit, wherein the substitution line has a pump for conveying substitution fluid into the extracorporeal circuit, wherein at least two, and preferably more than two, containers for the provision of a substitution fluid are connected separately and at the intake side of the pump to the substitution line, and wherein at least one pressure valve is arranged between the pump and at least one of the containers, said pressure valve allowing a flow of substitution fluid to the pump on an exceeding of an opening pressure.
US10994064B2 Peritoneal dialysate flow path sensing
The invention relates to systems and methods for sensing fluid characteristics of peritoneal dialysate infused into and removed from a patient during treatment. The systems and methods include sensors, processors, and flow paths for determining patient health based on the fluid characteristics of the peritoneal dialysate. The system can be a peritoneal dialysis cycler which can include an infusion line; an effluent line; at least one pump positioned in the infusion and/or effluent line; and at least one sensor fluidly connected to the effluent line. The sensor can be at least one of a flow sensor, an ion selective electrode, a pH sensor, a pressure sensor, a refractive index sensor, and a temperature sensor. The method can include infusing peritoneal dialysate through an infusion line; removing peritoneal dialysate through an effluent line; and determining at least one fluid characteristic of the peritoneal dialysate in the effluent line.
US10994057B2 Articles of poly(butylene succinate) and copolymers thereof
Resorbable implants, coverings and receptacles comprising poly(butylene succinate) and copolymers thereof have been developed. The implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing molding, pultrusion or other melt or solvent processing method. The implants, or the fibers preset therein, may be oriented. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators. The coverings, receptacles and implants described herein, may be made from meshes, webs, lattices, non-wovens, films, fibers, foams, molded, pultruded, machined and 3D printed forms.
US10994053B2 Coating of a vascular endoprosthesis
The invention relates to a method for coating a vascular endoprosthesis, wherein the outside of the vascular endoprosthesis is wetted at least partially with a first solution of an active substance, the vascular endoprosthesis is moved in a rotational movement about the longitudinal axis of the vascular endoprosthesis, and a radially acting mechanical force is applied to the outside of the vascular endoprosthesis. The rotational movement has the effect that the solution is carried outward by the centrifugal force, such that no active substance deposits in the interior of the vascular endoprosthesis. The application of a mechanical force to the outside of the vascular endoprosthesis then has the effect of creating crystallization nuclei, such that the active substance can crystallize out.
US10994052B2 Method for producing suspended form of ground decellularized extracellular matrix
The present invention relates to the field of pharmaceutics and medicine, in particular, to a method for producing a suspended form of ground decellularized extracellular matrix with size-controlled structural components, the suspended form not 5 requiring pre-hydration, and to a product produced by this method, for stimulation of reparative regeneration of tissues.
US10994051B2 Keratoprosthesis implanting method
A modified, novel surgical technique of Boston Keratoprosthesis (B-KPro) Type II is provided to restore the visual acuity in patients with bilateral end-stage ocular surface disorders, comprising 1) Preparing auricular cartilage; 2) Exposing corneal stroma and sclera surface and removing the corneal epithelium; 3) Assembling the keratoprosthesis device; 4) Implanting the assembled device into recipient cornea; 5) Implanting the autologous cartilage; and 6) Suturing the Tenon's capsule and conjunctiva to the ocular surface layer by layer to cover and reinforce the KPro.
US10994050B2 High yield and high precision bone graft substitute from stem cells
The invention comprises various materials and methods for the formation of bone within a patient using implanted bodies that are seeded with bone forming cells. The implants of the invention may comprise interlocking building blocks which allow for the formation of any desired structure. The geometry of the resulting bone structure can be tailored with great precision, and can be controllably integrated with native bone as desired. Advantageously, the methods result in the formation of functional, structured bone and avoid overgrowth, undergrowth, and the use of growth factors such as BMP-2.
US10994049B2 Dermal filler compositions for fine line treatment
The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions which are particularly advantageous for correction of fine lines in the face.
US10994047B2 Peptide dendrimers comprising fibrinogen-binding peptides
Peptide dendrimers and agents are described, which can be used for polymerising fibrinogen and as haemostatic agents. The peptide dendrimers comprise a branched core, and a plurality of fibrinogen-binding peptides separately covalently attached to the branched core. The branched core comprises: i) from two to ten multi-functional amino acid residues, wherein each fibrinogen-binding peptide is separately covalently attached to a multi-functional amino acid residue of the branched core; il) a plurality of multi-functional amino acid residues, wherein one or more fibrinogen-binding peptides are separately covalently attached to each of at least two adjacent multi-functional amino acid residues of the branched core; Hi) a plurality of multi-functional amino acid residues, wherein two or more fibrinogen-binding peptides are separately covalently attached to at least one of the multi-functional amino acid residues of the branched core; iv) a plurality of multi-functional amino acid residues, wherein two or more multi-functional amino acid residues are covalently linked through a side chain of an adjacent multi-functional amino acid residue; or y) a single multi-functional amino acid residue, and a fibrinogen-binding peptide is separately covalently attached to each functional group of the multi-functional amino acid residue, The. multi-functional amino acid residues comprise tri- or tetra-functional amino acid residues, or tri- and tetra-functional amino acid residues, or the single multi-functional amino acid residue is a tri- or tetra-functional amino acid residue.
US10994045B2 Process for making dry and stable hemostatic compositions
Described is a process for making a dry and stable hemostatic composition, said process comprising a) providing a first component comprising a dry preparation of a coagulation inducing agent, b) providing a second component comprising a dry preparation of a biocompatible polymer suitable for use in hemostasis, c) providing said first component and said second component in a combined form in a final container, c1) either by filling said first component and said second component into said final container so as to obtain a dry mixture in said final container, c2) or by providing said first component or said second component in said final container and adding said second component or said first component so as to obtain a combination of said first component with said second component in said final container, d) finishing the final container to a storable pharmaceutical device containing said first component and said second component in a combined form as a dry and stable hemostatic composition.
US10994044B2 Shape memory spacer fabric composite
The invention provides a shape memory spacer fabric composite, being a spacer fabric coated with a shape memory polymer layer, wherein the spacer fabric comprises a first outer layer, a second outer layer and an intermediate spacing layer connecting the first outer layer and the second outer layer; the shape memory polymer layer is made from at least one block or random copolymer selected from the group consisting of the following: polyesters, polyurethanes, polyamides, polyols; the copolymer has at least one phase transition temperature in a range of 40˜80° C.
US10994039B2 Storage apparatus and method for identifying a position of an object
An apparatus and method are disclosed for identifying the position of an object that is, or will be, used in a sterilization process. The apparatus comprises at least two containers and each container has a cavity configured to receive the object. At least one visual indicator corresponds to each container. A programmable hardware device is configured to receive an identifier. Responsive to receipt of the identifier, the programmable hardware device is configured to indicate a position of at least one of the containers that corresponds to the identifier utilizing the visual indicator.
US10994038B2 Systems, devices, and methods for generating chlorine dioxide
Methodologies, systems, and devices are disclosed for generating a chemical compound. A reaction chamber holds an amount of a precursor chemical, an activator chamber holds an amount of an activator chemical, and a quenching and neutralizer chamber holds an amount of quenching and neutralizing chemicals. A pump transfers the activator chemical from the activator chamber to the reaction chamber, where the activator chemical reacts with the precursor chemical to form the desired chemical compound. The desired chemical compound is allowed to exit the reaction chamber. Subsequently, the pump transfers the quenching and neutralizing chemicals from the quenching and neutralizer chamber to the reaction chamber, resulting in a quenched and neutralized solution.
US10994037B1 UVC sanitizing accessory
An accessory device is provided that emits ultraviolet (UV) light and that receives electrical power from an electronic device (e.g., a smart phone). The accessory device notifies a user when the amount of UV light emitted by the accessory device is sufficient to sanitize a surface when the accessory device has been held at a predetermined distance from the surface.
US10994035B2 Disinfecting system with performance monitoring
A system includes multiple devices configured to emit and detect germicidal radiation. Each of the multiple devices operates in emitting mode when connected to a drive source in a forward bias configuration and operates in detecting mode when disconnected from the drive source or when connected to the drive source in a reverse bias configuration. Cycling circuitry generates a sequence of control signals that control switching circuitry to change the connections of the devices to the drive source in a cycle in which one or more of the multiple devices are switched to detecting mode and senses radiation emitted by one or more of the multiple devices simultaneously operating in emitting mode. Each device operating in detecting mode generates a signal in response to the sensed radiation. Detection circuitry detects signals of the devices operating in detecting mode and generates a detection output in response to the detected signals.
US10994034B1 Apparatus for inactivation of airborne pathogens and pathogens on the surface of an object
An apparatus for the inactivation of airborne pathogens and pathogens on the surface of an object. The apparatus including a housing with an intake region and an exhaust region and an airflow path disposed between the intake and exhaust regions. The apparatus also includes a space within the housing for placement of the object as well as an intake fan and an oxidant generator proximate the intake fan. The apparatus includes an air filter disposed in the airflow path for removing particulates and pathogens and passes the intake air through either or both of an activated carbon filter and a catalyst to convert the oxidant into oxygen.
US10994031B2 Composites and compositions for therapeutic use and methods of making and using the same
Disclosed herein are embodiments of composites and compositions that can be used for therapeutic applications in vivo and/or in vitro. The disclosed composites can comprise cores having magnetic nanoparticles, quantum dots, or combinations thereof and zwitterionic polymeric coatings that facilitate solubility and bioconjugation. The compositions disclosed herein can comprise the composites and one or more biomolecules, drugs, or combinations thereof. Also disclosed herein are methods of making the composites, composite components, and methods of making quantum dots for use in the composites.
US10994030B2 Compositions and methods for measuring and expanding blood volume
A method for measuring, adjusting and maintaining the level of blood volume in a patient is described. A blood volume expander composition includes, in combination, a standard unmodified protein, colloid or crystalloid and a fluorescently-labeled protein, colloid or crystalloid of approximately the same molecular weight. The use of blood volume expanders to measure, adjust and maintain the level of blood volume in a patient also is described.
US10994029B2 Conformational restriction of cyanine fluorophores in far-red and near-IR range
Conformationally restricted cyanine fluorophores, as well as methods of making and using the compounds, are described. The conformationally restricted cyanine fluorophores have a chemical structure according to Formula I, or a stereoisomer or pharmaceutically acceptable salt thereof: wherein A is and wherein each “*” designates an attachment point of A.
US10994028B2 Scalable manufacturing process to produce recombinant lentiviral vectors in serum-free suspension cell culture system
Methods for preparing highly purified rLV vector formulations at the scale needed to meet anticipated demand for human gene therapy are provided.
US10994027B2 Immunostimulating vector system
Provided is a novel vector for immunostimulation and methods of using same in immunotherapy, in particular cancer immunotherapy. The novel vector comprises nucleic acid sequences encoding 4-1BB ligand (4-1BBL, CD137 ligand), single chain IL-12 (sc IL-12) and IL-2, wherein the vector provides for an increased expression of 4-1BBL as compared to the expression levels of sc IL-12 and IL-2. Specifically, the nucleic acid sequences encoding 4-1BBL, sc IL-12 and IL-2 are organized in the vector in 5′ to 3′ orientation in a sequential order 1, 2, 3, with the proviso that the gene encoding sc IL-12 is not at position 1. Embodiments of the present disclosure include virus particles comprising the novel vector as well as cancer or immune cells transduced or transfected with the novel vector.
US10994025B2 Argonaute protein-double stranded RNA complexes and uses related thereto
The invention relates to methods of improving efficacy and enhancing silencing of target genes using Ago2 protein-dsRNA complex (RNP) of the invention.
US10994023B2 Pyrrolobenzodiazepines and conjugates thereof
A compound which is either A: and salts and solvates thereof, as well as their conjugates with a cell-binding agent.
US10994021B1 Tetravalent antibody-drug conjugates and use thereof
An antibody-drug conjugate (ADC) or a pharmaceutically acceptable salt thereof, is provided. The ADC includes a tetravalent monoclonal antibody conjugated to a cytotoxic drug by a chemical linker. The monoclonal antibody includes two long chains and four short chains. Each of the long chains includes a first segment and a second segment, the first segment located proximal to the N-terminus of the long chain, and the second segment located proximal to the C-terminus of the long chain. Each of the first segment and second segment pairs with one of the short chains to form an antigen-binding fragment domain, therefore forming four antigen-binding fragment domains having specificity toward the same antigen. Pharmaceutical composition including the ADC and methods of treating diseases using the compositions are also provided.
US10994020B2 Nucleic acid-polypeptide compositions and methods of inducing exon skipping
Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
US10994016B2 Graphene oxide mediated cellular delivery of gadolinium-labeled molecules
A method of bioactive molecule delivery includes providing a first aqueous medium comprising native graphene oxide and a second aqueous medium comprising a bioactive molecular component that includes Gd(III)-labeled molecules; mixing said first and second media to form a mixture thereof; co-incubating the mixture for a first period of time for coupling said molecular component on a surface of said native graphene oxide, to provide a co-incubation product; and contacting a cellular medium with said co-incubation product for a second period of time for cellular delivery of said bioactive molecular component.
US10994011B2 Pharmaceutical composition comprising anti-human TSLP receptor antibody
Provided is a stable pharmaceutical composition comprising an anti-human TSLP receptor antibody, capable of inhibiting the generation of chemically modified substances, such as deamidated forms and oxidized forms, or degradants, or multimers. The pharmaceutical composition comprises an anti-human TSLP receptor antibody, a pharmaceutically acceptable buffer, arginine or a pharmaceutically acceptable salt thereof, and a surfactant.
US10994008B2 Modulation of tumor immunity
Methods of treating proliferative disorders are described. In particular, combination treatment with a GITR agonist and a PD-1 antagonist are provided.
US10994007B2 Immunity inducer
Disclosed is an immunity inducer. The immunity inducer comprises virus like particles; the virus like particles comprise a virus-derived outer coat protein and an antigen-bound protein comprising an exogenous antigen; the outer coat protein constitutes an outer coat of the virus like particles, and the antigen-bound protein is comprised in the outer coat; and the virus like particles induce an immune effect of a living body on the antigen.
US10994004B2 Immunogenic compositions comprising Lawsonia intracellularis
The present invention provides combination vaccines that comprise an immunological agent effective for reducing the incidence of or lessening the severity of PPE caused by L. intracellularis, and one or more immunological active components effective in treatment and/or prophylaxis of at least one further disease-causing organism for swine. Moreover, the present invention also relates to a kit that comprises an immunological agent effective for reducing the incidence of or lessening the severity of PPE caused by L. intracellularis, and one or more immunological active components effective in treatment and/or prophylaxis of at least one further disease-causing organism for swine.
US10994000B2 Rabbit coccidiosis vaccine and application thereof
The present invention discloses a rabbit coccidiosis vaccine and application thereof, the vaccine comprises 100 to 800 Eimeria media/dose, 200 to 1600 Eimeria magna/dose, and 100 to 800 Eimeria intestinalis/dose. The composition of the vaccine possesses the characteristics as scientific reasonable, low cost, no drug residue or drug resistance or environmental pollution would occur, good immunogenicity and safe to use. After oral immunization in rabbits, it may effectively resist the infections of 1×105 Eimeria media, 5×104 Eimeria magna and 3×103 Eimeria intestinalis. It also may be used to prepare a pharmaceutical preparation against rabbit coccidiosis.
US10993998B2 Determinants of cancer response to immunotherapy by PD-1 blockade
Molecular determinants of cancer response to immunotherapy are described, as are systems and tools for identifying and/or characterizing cancers likely to respond to immunotherapy.
US10993997B2 Methods for profiling the t cell repertoire
The present disclosure relates to methods for profiling subject specific and personalized T cell receptor (TCR) repertoires using a single-cell sequencing method. More particularly, disclosed are methods for determining binding of T cell receptors to subject specific neoantigens. In addition, the techniques herein may identify the antigenic targets of T cell receptors in the context of tumor neoantigens. Moreover, the present disclosure enables the discovery of T cell targets in numerous diseases, with implications for understanding the basic mechanisms of the mammalian immune response and for developing antigen-specific diagnostic markers and therapies. Finally, cloned TCRs can be used to formulate personalized immunotherapies for those inflicted with a disease, such as cancer.
US10993996B2 Digestive enzyme composition suitable for enteral administration
The present invention is directed to a digestive enzyme composition comprising an enterically coated digestive enzyme product, administrable nutritional medium, and a pharmaceutically acceptable low viscosity oily ingredient. The process for the preparation of the digestive enzyme composition comprises adding an enterically coated digestive enzyme product to a administrable nutritional medium and pharmaceutically acceptable low viscosity oily ingredient. The invention further provides a method for treating a patient suffering from exocrine pancreatic insufficiency related condition comprising administering to the patient a therapeutically effective dose of the digestive enzyme composition by means of a feeding tube.
US10993990B2 Methods and compositions for treating autoimmune and inflammatory conditions
Described herein are compositions and methods for inhibiting an inflammatory or autoimmune response and for inducing immune tolerance in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an antigen presenting cell (APC)-targeted antibody operatively linked to IL-10 or a fragment thereof. The compositions and methods described herein are useful for treating inflammatory and autoimmune disorders.
US10993986B2 Pharmaceutical constructs with enhanced binding affinity with albumin
The present disclosure provides various molecular constructs having a plurality of fatty acids and a functional element. Methods for treating various diseases using such molecular constructs are also disclosed.
US10993979B2 Botanical tinctures
Disclosed herein are botanical tinctures that can be variously formulated and packaged and used as dietary supplements and in the prevention and treatment of symptoms associated with disorders affecting digestion or the digestive tract (e.g., symptoms of functional gastrointestinal disorders, FGIDs).
US10993973B2 Pharmaceutical composition and food composition with strains of lactic acid bacteria for improving of kidney disease and inhibiting inflammation
The present invention provides a lactobacillus strain-containing pharmaceutical composition and food composition for improving of kidney disease and inhibiting inflammation, which comprises an isolated lactic acid bacteria strain. The isolated lactic acid bacteria strain is at least one selected from a group including BLI-02 strain, CGMCC No. 15212, Bifidobacterium longum subsp. infantis, TYCA06 strain, CGMCC No. 15210, Lactobacillus acidophilus, VDD088 strain, CGMCC No. 15211, Bifidobacterium bifidum, and combinations thereof.
US10993969B2 Methods and materials for treating nerve injuries and neurological disorders
This document provides methods and materials for treating nerve injuries and/or neurological disorders. For example, compositions including an amnion tissue preparation and/or a stem cell preparation as well as methods for using such compositions to treat a nerve injuries and/or neurological disorders are provided.
US10993968B2 Methods and articles of manufacture for cosmetic results
Methods are disclosed for the collection and processing of amniotic material in animals. These methods involve collection of amniotic material directly during parturition or cesariean section in animals for the processing of regenerative wound treatments and tissue repairs without culturing or utilization of any excess manipulation of tissue. These materials are used to effect a cosmetic result.
US10993966B2 Pluripotent stem cell for treatment of cerebral infarction
An object of the present invention is to provide a novel medical application to regenerative medicine that uses pluripotent stem cells (Muse cells). The present invention provides a cell preparation for treating cerebral infarction and sequelae associated therewith that contains SSEA-3-positive pluripotent stem cells isolated from mesenchymal tissue in the body or cultured mesenchymal cells. The cell preparation of the present invention is based on a brain tissue regeneration mechanism by which Muse cells differentiate into nerve cells and the like in damaged brain tissue by administering Muse cells into cerebral parenchyma.
US10993965B2 Lyophilized platelet lysates
The present disclosure is drawn to compositions and methods of making and using lyophilized platelet lysates. Specifically, a method of preparing a composition suitable for therapeutic use or as a culture medium can comprise steps of concentrating platelets from a platelet source to form a platelet rich portion of the platelet source, and lysing the platelets in the platelet rich portion to form a plurality of lysates. An additional step includes lyophilizing the lysates to form lyophilized platelet lysates in a composition with released concentrations of available growth factors, cytokines, and chemokines. In one example, at 30%, by platelet count, of platelets from a platelet source can be lysed using this process.
US10993964B2 Peptides and combination of peptides of non-canonical origin for use in immunotherapy against different types of cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10993962B2 Peptides and combination of peptides of non-canonical origin for use in immunotherapy against different types of cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10993961B2 Dialysis precursor composition
The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consist of powder components comprising sodium chloride, at least one dry acid and at least one magnesium salt, and optionally potassium salt, calcium salt, and glucose. According to the invention said at least one magnesium salt and said optional glucose, are present as anhydrous components in said dialysis acid precursor composition.
US10993960B1 Pharmaceutical composition
A pharmaceutical composition includes polymer units α and β, each having a hydrophilic polymer chain bound to a cationic polymer chain, and a drug. The polymer units α and β are radially arranged such that the cationic polymer chains are directed inward and the hydrophilic polymer chains are directed outward, thereby forming a micelle with the drug encapsulated in the micelle. The cationic polymer chain of the polymer unit α has a phenylboronic acid group in a side chain, and the cationic polymer chain of the polymer unit β has a phenylboronic acid binding site in a side chain. The phenylboronic acid group and the phenylboronic acid binding site form a cross-linked structure that can dissociate in an acidic environment and/or in the presence of a substance capable of competitive binding.
US10993959B2 Methods and compositions for increasing the suppressive function of regulatory T-cells (Tregs)
Methods and compositions for increasing the suppressive function of regulatory T-cells (Tregs) are provided.
US10993958B1 Aldehyde functional monoterpenoids for the treatment of coronavirus infection
Compositions comprising aldehyde functional monoterpenoids in combination with 3,3′,4′,7-tetrahydroxyflavone, zinc, and a 5-beta-D-Ribofuranosylpicolineamide adenine-dinucleotide molecule are provided for treating viral infections, e.g., coronavirus infections such as COVID-19.
US10993953B2 Method for treating cancer using chemokine antagonists
What is described is a method for treating cancer in a patient assaying levels of (a) CXCR1 and/or CXCR2 ligands or (b) myeloid derived suppressor cells (MDSCs) and/or neutrophils in the patient, and if the patient has increased levels of (a) or (b), then administering a therapeutically effective amount of a compound having a structure selected from the group consisting of formulas SX-517, SX-576, and SX-682
US10993951B2 Fosfomycin formulation for parenteral administration
The field of the present invention is that of fosfomycin formulations for parenteral administration, in particular for intravenous administration. Formulations of the prior art provide fosfomycin as a powder to be diluted directly prior to the administration. The aim of the invention is to provide a fosfomycin formulation for parenteral administration which is easier to produce and administer or which lowers the risk of puncture injuries for healthcare professionals and the health risks for the patients (for example due to contamination or incorrect dosages) by preventing additional processing steps. During the course of the invention, it was surprisingly shown that fosfomycin is much more stable in an aqueous solution than what is commonly assumed. The invention therefore provides a closed container which contains an aqueous solution for parenteral administration, wherein at least one pharmaceutically acceptable salt of fosfomycin, in particular fosfomycin disodium salt, and a pharmaceutically acceptable acid, in particular succinic acid, are dissolved in the solution. Preferred containers are breakable ampoules made of plastic or glass, puncturable vials, infusion bags, or syringes ready for injection.
US10993947B2 Treatment of skin lesions
The present invention is relates to a compound of formula (I), wherein X1, X2 and X3 are, independently of each other, N or CH; with the proviso that at least two of X1, X2 and X3 are N; Y is N or CH; W is H or F; with the proviso that when W is F, then X1, X2 and X3 are N; R1 and R2 are independently of each other (i) a morpholinyl of formula (II) wherein the arrow denotes the bond in formula (I); and wherein R3 and R4 are independently of each other H, C1-C3alkyl optionally substituted with one or two OH, C1-C2fluoroalkyl, C1-C2alkoxy, C1-C2alkoxyC1-C3alkyl, CN, or C(O)O—C1-C2alkyl; or R3 and R4 form together a bivalent residue —R5R6— selected from C1-C3alkylene optionally substituted with 1 to 4 F, —CH2—O—CH2—, —CH2—NH—CH2—, or any of the structures wherein the arrows denote the bonds in formula (II); or (ii) a saturated 6-membered heterocyclic ring Z selected from thiomorpholinyl and piperazinyl, optionally substituted by 1 to 3 R7; wherein R7 is independently at each occurrence C1-C3alkyl optionally substituted with one or two OH, C1-C2fluoroalkyl, C1-C2alkoxyC1-C3alkyl, C3-C6cycloalkyl; or two R7 substituents form together a bivalent residue —R8R9— selected from C1-C3alkylene optionally substituted with 1 to 4 F, —CH2—O—CH2— or —O—CH2CH2—O—; with the proviso that at least one of R1 and R2 is a morpholinyl of formula II; and prodrugs, metabolites, tautomers, solvates and pharmaceutically acceptable salts thereof, for use in the prevention or treatment of a skin lesion in a subject.
US10993946B2 Systems and methods for treating cancer
Embodiments of the invention provide a method of treating cancer, the method comprising providing a subject having cancer cells, and contacting the cancer cells with a therapeutically effective amount of a G2/M checkpoint inhibitor. Embodiments of the invention also provide a method of treating cancer in a subject, the method comprising the steps of: (a) receiving a sample of the cancer cells from the subject; (b) determining if at least a portion of the sample of the cancer cells is LKB1 deficient; and (c) contacting the cancer cells with a therapeutically effective amount of a G2/M checkpoint inhibitor. Embodiments of the invention also provide a method of treating cancer in a subject, the method comprising contacting the cancer cells with a therapeutically effective amount of a Wee1 inhibitor and a therapeutically effective amount of a second pharmaceutical composition. Embodiments of the invention also provide a method of prognosing or determining the severity of cancer in a subject comprising (a) determining the presence or absence of LKB1 in the cancer cells of the subject; and (b) prognosing the severity of cancer based on the presence of LKB1 deficiency in the cancer cells of the subject.
US10993945B2 CDK8-CDK19 selective inhibitors and their use in anti-metastatic and chemopreventative methods for cancer
The invention relates to the compounds and methods for inhibiting the Cyclin-Dependent Kinase Inhibitor (CDKI) pathway. More particularly, the invention relates to compounds and methods for inhibiting the CDKI pathway for studies of and intervention in senescence-related and other CDKI-related diseases. The invention provides new compounds having improved solubility and/or potency, and methods for their use. In various aspects, the invention relates to the treatment of cancer. The invention provides methods for chemoprevention and prevention of tumor recurrence or metastasis. The invention further provides diagnostic techniques for treatment for certain cancer types. The invention utilizes specific inhibitors of CDK8/19 and/or measurement of CDK8 levels in a patient.
US10993943B2 Crystalline forms of selinexor and process for their preparation
The present disclosure relates to solid state forms of Selinexor, processes for preparation thereof and pharmaceutical compositions thereof.
US10993941B2 Methods for the administration of certain VMAT2 inhibitors
Provided are methods of administering a vesicular monoamine transport 2 (VMAT2) inhibitor chosen from valbenazine and (+)-α-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol, or a pharmaceutically acceptable salt and/or isotopic variant thereof, to a patient in need thereof wherein the patient has mild, moderate, or severe hepatic impairment.
US10993939B2 Compositions for treating or preventing vasomotor symptoms
The present disclosure is directed to compositions and methods for treating or preventing vasomotor symptoms such as hot flashes, comprising a Transient Receptor Potential Melastatin 8 (TRPM8) antagonist and administering a TRPM8 antagonist, respectively.
US10993936B2 Method of treating one or more symptoms of pulmonary fibrosis by administering inhibitors of nicotinamide phosphoribotransferase
Inhibition of the expression and/or function of nicotinamide phosphoribosyltransferase (NAMPT) can reduce, prevent or reverse the pathophysiological vascular changes associated with the onset and progression of Pulmonary Fibrosis. Compositions and methods to inhibit the expression and function of NAMPT for treating and preventing Pulmonary Fibrosis in a subject in need are provided. The compositions and methods are useful for the modulation of pathophysiological processes that contribute to the development and progression of Pulmonary Fibrosis by reducing lung inflammation, aberrant myofibroblast accumulation and deposition of collagen in fibrotic foci.
US10993927B2 Taxane particles and their use
Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.
US10993926B2 Use of IDHP in preparation of drug or health product for prevention and treatment of coronary atherosclerosis disease
Use of isopropyl β-(3,4-dihydroxyphenyl)-α-hydroxypropionate (IDHP) in the preparation of a drug or a health product for prevention and treatment of coronary atherosclerosis diseases. The IDHP can also be used to inhibit platelet aggregation, to promote angiogenesis, and to prepare a drug and a health product for prevention and treatment of senile vascular dementia.