| Document | Document Title |
|---|---|
| US10781353B2 |
Use of a composition for stabilizing a geological formation in oil fields, gas fields, water pumping fields, mining or tunnel constructions
The present invention relates to the use of a composition for stabilizing a geological formation in oil fields, gas fields, water pumping fields, mining or tunnel constructions. The composition has a hardening temperature in the range from about 40° C. to about 120° C. and can therefore be used to stabilize a geological formation in oil fields, gas fields, water pumping fields as well as in mining or tunnel constructions. |
| US10781349B2 |
Thermal interface material including crosslinker and multiple fillers
A thermal interface material includes, in one exemplary embodiment, at least one polymer, at least one phase change material, at least one crosslinker, and at least one thermally conductive filler. The at least one thermally conductive includes a first plurality of particles having a particle diameter of about 1 micron or less. The at least one thermally conductive filler comprises at least 80 wt. % of the total weight of the thermal interface material. A formulation for forming a thermal interface material and an electronic component including a thermal interface material are also provided. |
| US10781348B2 |
Inhibited aqueous deicing composition
Disclosed is an aqueous deicing and/or anti-icing composition, and the use thereof on areas in need of deicing and/or anti-icing, exhibiting substantially improved corrosion inhibition, conductivity inhibition and/or hydrogen embrittlement inhibition. Said composition comprises 40-60% by weight of at least one alkali metal carboxylate, 0.1-0.5% by weight of benzoic acid and/or at least one alkali metal benzoate, 0.05-0.5% by weight of at least one alkali metal phosphate, 0.005-0.05% by weight of at least one alkali metal metasilicate, and 0.01-0.15% by weight of succinic acid and/or at least one alkali metal succinate. Balance to 100% by weight is water and said composition is pH adjusted to pH 9-12 by addition of at least one alkali metal hydroxide and/or carbonate. Disclosed is also a method of obtaining corrosion inhibition, conductivity inhibition and/or hydrogen embrittlement inhibition by addition of 0.01-0.15% by weight of succinic acid and/or at least one alkali metal succinate to an aqueous deicing and/or anti-icing composition. |
| US10781346B2 |
Corrosion-inhibiting, radically cureable composition
A composition for sealing joints, penetrations and other leaks in particular in the construction field, including at least one ethylenically unsaturated, radically polymerizable water-soluble compound, at least one radical initiator, water and at least one corrosion inhibitor including at least one phosphate. The corresponding composition has a corrosion-inhibiting effect with respect to metal. |
| US10781345B1 |
Method of preparing polyurethane hot melt adhesive with high temperature resistance
A method of preparing polyurethane hot melt adhesive with high temperature resistance generally includes the following steps: (1) adding isocyanate with a silane modifier in a reactor in an inert atmosphere, heating and stirring, then adding chemical dehydrant into the reactor and mixing evenly; (2) adding dehydrated diluent and tackifier resin to the reactor while maintaining the inert atmosphere and heating, adding dehydrated polyester polyol and polyether polyol, stirring, and allowing to react at constant temperature for a predetermined time period; (3) adding dehydrated polyether amine, stirring, and heating; and (4) adding a catalyst, vacuumizing, discharging materials and packaging the materials in an airtight container. The hot melt adhesive made according to the new method has a variety of improved physical and mechanical properties, including improved high temperature resistance, cold and heat shock resistance, drop resistance toughness, high adhesive strength, salt spray resistance and moisture and heat aging resistance. |
| US10781340B2 |
Silicone hydrogel lenses with water-rich surfaces
The invention is related to a hydrated silicone hydrogel contact lens having a layered structural configuration: a lower water content silicone hydrogel core (or bulk material) completely covered with a layer of a higher water content hydrogel totally or substantially free of silicone. A hydrated silicone hydrogel contact lens of the invention possesses high oxygen permeability for maintaining the corneal health and a soft, water-rich, lubricious surface for wearing comfort. |
| US10781335B2 |
Functional film
A functional film includes layer (A) containing a resin and layer (B) containing a compound containing a perfluoropolyether group. Layer (B) has a microrelief pattern structure on a surface remote from layer (A). In elemental analysis by X-ray photoelectron spectroscopy from the layer (B) side, the functional film satisfies formula (1): D1<2×X1, wherein X1 is a thickness (nm) of layer (B); and D1 is a depth (nm) at which fluorine atoms exhibit a concentration of 1 atom % or lower. In carbon 1s spectrum measurement by X-ray photoelectron spectroscopy from the layer (B) side, the functional film satisfies formula (2): D2<2×X1, wherein X1 is the thickness (nm) of layer (B); and D2 is a depth (nm) at which no peak is detected within a bond energy range of 290 to 300 eV. |
| US10781334B2 |
Compositions comprising a copolymer of a solid grade oligomer and a hydrophobic monomer and/or a gas-phase monomer and methods of making the same
The present disclosure relates to compositions comprising a copolymer derived from polymerizing a hydrophobic monomer and/or a gas-phase monomer in the presence of a solid grade oligomer. In some embodiments, the hydrophobic monomer includes styrene and butadiene. In some embodiments, the copolymer is derived from polymerizing a gas-phase monomer. The present disclosure also relates to methods of making the disclosed compositions. The compositions disclosed herein can be used in a variety of applications including, but not limited to, asphalt compositions, paints, coatings, paper binding and coating compositions, foams, or adhesives. |
| US10781332B2 |
Wear-resistant and low-friction polymer composite comprising nano-diamond powder treated with hydrogen plasma, and method for producing polymer composite
Provided are a polytetrafluoroethylene (PTFE) coating and a preparing method of the same. The PTFE coating includes: a nanodiamond powder whose surface is treated with a plasma using a hydrogen-containing reactive gas to remove amorphous carbon, the nanodiamond powder being ground in a commercially available state and having a surface to which a functional group is attached; and a PTFE solution dispersing the nanodiamond powder. |
| US10781323B2 |
3-dimensional printing
The present disclosure is drawn to coalescent inks and material sets for 3D printing. The coalescent ink can include an organic-soluble near-infrared dye having a peak absorption wavelength from 800 nm to 1400 nm. The coalescent ink can also include water and an organic co-solvent. |
| US10781321B2 |
Coating agent for oil seal
A coating agent for oil seal comprising 10 to 160 parts by weight of a filler having a particle size of 0.5 to 30 □m based on 100 parts by weight of isocyanate group-containing 1,2-polybutadiene and being prepared as an organic solvent solution, wherein a contact angle between a substrate surface coated with the coating agent and engine oil is less than 35°. The coating agent can improve wettability with oil and reduce dynamic friction coefficient in oil, while increasing the roughness of the coating surface. Thus, low torque characteristics can be achieved, while maintaining excellent seal performance inherent in oil seal. |
| US10781318B2 |
Graphene based corrosion-resistant coating
In one aspect, a coating for protecting a component exposed to a corrosive environment includes an epoxy phenolic resin and graphene nanoplatelets. In another aspect, a method of protecting a an article exposed to a corrosive environment includes applying a corrosion-resistant epoxy phenolic coating to a surface of the article exposed to a corrosive environment and curing the corrosion-resistant epoxy phenolic coating. The coating comprises 0.1 to 2.0 weight percent graphene nanoplatelets containing 5 to 15 atomic percent oxygen. |
| US10781317B2 |
Tunable materials
A corrosion resistant material is described including a substrate, a first material including less than about 90% of an amino group or epoxy group, between about 0.05% and about 50% siloxane, between about 5% and about 80% nanoparticles, microparticles, or macroparticles, and between about 0.1% and about 5% of a first functionalized graphitic material, a second material including less than about 90% of a silyl group, between about 0.05% and about 50% siloxane, between about 5% and about 80% nanoparticles, microparticles, or macroparticles, and between about 0.1% and about 5% of a second functionalized graphitic material, and a third material including less than about 90% of an amino group or epoxy group and a silyl group, between about 0.05% and about 50% siloxane, between about 5% and about 80% nanoparticles, microparticles, or macroparticles, and between about 0.1% and about 5% of a third functionalized graphitic material. |
| US10781313B2 |
Composition comprising esters of lignin and oil or fatty acids
The present invention relates to a composition comprising a carrier liquid and lignin or lignin derivatives; wherein at least one of the hydroxyl groups of the biomass have been substituted with ester groups. The composition may be used for preparing fuels or lubricants. |
| US10781311B2 |
Semi-crystalline build materials
A polymeric material includes a semi-crystalline polymer and a secondary material wherein when the secondary material is combined with the semi-crystalline polymer to form a blend having at least a 3° C. reduction in a hot crystallization temperature relative to the neat semi-crystalline polymer. |
| US10781310B2 |
Polymer polyol stabilizers
This invention relates to novel macromers comprise the reaction product of a starter compound having a functionality of 2 to 8 and a hydroxyl number of 20 to 50, with a modified isocyanate component. This invention also relates to preformed stabilizers prepared from these macromers, and to polymer polyols prepared from these novel macromers and novel preformed stabilizers. The present invention also relates to processes for preparing these compositions, to polyurethane foams comprising these polymer polyols, and to processes for preparing these polyurethane foams. |
| US10781308B2 |
Resin composition for laser welding and welded body thereof
A resin composition for laser welding contains: relative to 100 mass parts of (A) a thermoplastic polyester resin material that contains a polybutylene terephthalate homopolymer and at least one of a polybutylene terephthalate copolymer, a polyethylene terephthalate resin, and a polycarbonate resin, 0.0005 to 0.5 mass parts of (B) nigrosine; and 0.01 to 2 mass parts of (C) a colorant containing at least an anthraquinone dye C1 having a maximum absorption wavelength in a range of 590 to 635 nm, a perinone dye C2 having a maximum absorption wavelength in a range of 460 to 480 nm, and an anthraquinone dye C3 having a maximum absorption wavelength in a range of 435 to 455 nm, at C1:C2:C3=24 to 41:24 to 39:22 to 46 as the mass ratio relative to 100 mass parts for a total of C1, C2, and C3. |
| US10781307B2 |
Polyoxymethylene resin molded article, sliding member, and ramp for hard disk
A polyoxymethylene resin molded article comprising 100 parts by mass of a polyoxymethylene resin (A) and 0.1 to 5 parts by mass of a sliding agent (B), wherein four or more dispersion domains of the sliding agent (B) are present in a region of 1000 nm in depth from a surface of the molded article and 12000 nm in width, and the dispersion domain has an average minor diameter of 300 nm or less, and an average major diameter of 600 nm or more and 5000 nm or less. |
| US10781305B2 |
Resin composition and membrane structure comprising the same
Provided is an ECTFE resin composition that is superior in transparency and resistant to yellowing for an extended period of time. The ECTFE resin composition generates a smaller amount of acidic gases, for example, when it is extrusion molded at high temperature. It is an ethylene-chlorotrifluoroethylene copolymer resin composition including a bisphenol-based antioxidant. It is preferably an ethylene-chlorotrifluoroethylene copolymer resin composition additionally including a phosphorus-based antioxidant. |
| US10781302B2 |
Rubber mixtures
The invention relates to rubber mixtures, wherein these comprise at least one rubber, excluding silicone rubber, and at least one silatrane of general formula (I) G-Si(—O—CX1X2—CX1X3—)3N (I) The rubber mixture is produced by mixing at least one rubber and a silatrane of formula (I).The silatrane of formula (I) may be used as a secondary accelerator in rubber mixtures. |
| US10781298B2 |
Copolymer, rubber composition using same, and tire
The present invention relates to a copolymer including a monomer unit (a) derived from isoprene and a monomer unit (b) derived from farnesene; a process for producing the copolymer including at least the step of copolymerizing isoprene with farnesene; a rubber composition including (A) the copolymer, (B) a rubber component and (C) carbon black; a rubber composition including (A) the copolymer, (B) a rubber component and (D) silica; a rubber composition including (A) the copolymer, (B) a rubber component, (C) carbon black and (D) silica; and a tire using the rubber composition at least as a part thereof. |
| US10781292B2 |
Method of foaming a milled precursor
A method of making a foamed article comprises (a) milling a block or sheet of thermoplastic polymer to form a precursor; (b) crosslinking the thermoplastic polymer; (c) heating the precursor to a first temperature to soften the thermoplastic polymer; (d) infusing the thermoplastic polymer with at least one inert gas at a first pressure that is sufficient to cause the at least one inert gas to permeate into the softened thermoplastic polymer; and (e) while the thermoplastic polymer is softened, reducing the pressure to a second pressure below the first pressure to at least partially foam the precursor into a foamed article, wherein the foamed article is substantially the same shape as the precursor. |
| US10781288B2 |
Polyimide precursor and polyimide
A polyimide precursor including at least one repeating unit represented by the following chemical formula (1): in which A is an arylene group; and X1 and X2 are each independently hydrogen, an alkyl group having 1 to 6 carbon atoms, or an alkylsilyl group having 3 to 9 carbon atoms, and a polyimide obtained from the polyimide precursor has a coefficient of linear thermal expansion from 50° C. to 400° C. of 100 ppm/K or less. |
| US10781284B2 |
Polyurethane-polyisocyanurate compound comprising outstanding mechanical properties
Polyurethane-polyisocyanurate compounds and processes for preparing polyurethane-polyisocyanurate compounds are disclosed herein. A process includes mixing component (a) polyisocyanate with component (b) a mixture obtainable by introducing an alkali metal or alkaline earth metal salt into a compound R—NH—CO—R containing urethane groups, where R is not hydrogen and is not COR, component (c) compounds containing one or more epoxide groups, component (d) one or more compounds having at least two isocyanate-reactive groups, comprising compounds having NH2 and/or primary OH groups, and component (e) optionally fillers and other additives, to form a reaction mixture, and reacting the reaction mixture to form the polyurethane-polyisocyanurate compound, wherein the molar amount of alkali metal and/or alkaline earth metal ions in the reaction mixture per mole of urethane group in component (b) is 0.0001 to 3.5 and the isocyanate index is greater than 150. Use of polyurethane-polyisocyanate compounds for producing vehicle parts is also disclosed. |
| US10781282B2 |
Flame retardant polyol
A reaction system, such as for forming a rigid polyurethane foam, includes a flame retardant polyol that is a brominated reaction product of a cardanol component, a bromine component, and an additive component. The cardanol component includes at least 80 wt % of cardanol, based on the total weight of the cardanol component, and the bromine component including at least 80 wt % of bromine, based on the total weight of the bromine component. |
| US10781280B2 |
Method for producing thermosetting phenolic resins and phenolic resins obtainable by the method
A method for producing thermosetting phenolic resins includes the step of reacting a polycondensable phenolic compound with 5-hydroxymethylfurfural (HMF) under conditions leading to the formation of polycondensation products. The HMF includes at least one HMF oligomer, and the reaction step is carried out at pH values greater than 7 for more than 60 minutes. Further, thermosetting phenolic resins may be used for producing a wood composite material. |
| US10781277B2 |
Method of forming a composite nanoparticle for nanofibers from a poly-(acrylonitrile-co-itaconic acid) poly 3-methoxythipohene (P(AN-co-IA)-PMOT) nano composite solution
The nano-fibre derivative method includes polymerization of 3-methoxthiophene (MOT) monomer on Poly(acrylonitrile co-itaconic acid) matrix and by use of electro-spinning of the produced nano-particulate. |
| US10781275B2 |
Polymerizable monomers and method of polymerizing the same
Provided herein are photopolymerizable monomers, optionally for use as reactive diluents in a high temperature lithography-based photopolymerization process, a method of producing polymers using said photopolymerizable monomers, the polymers thus produced, and orthodontic appliances comprising the polymers. |
| US10781271B2 |
Method for producing brominated and halohydrated polymers
Conjugated diene polymers such as a styrene-butadiene copolymer are sequentially brominated by reaction with a quaternary ammonium tribromide or quaternary phosphonium tribromide and halohydrated by reaction with an N-haloimide compound. This produces a brominated and halohydrated polymer with very good thermal stability. The product is useful as a flame retardant in a variety of polymer systems. |
| US10781266B2 |
Antibodies specific to alpha-enolase and uses thereof
An antibody, or an antigen-binding fragment there, binding human ENO1 (GenBank: AAH506421.1) is provided. Methods for treating an ENO1 protein-related disease or disorder, inhibiting cancer invasion and diagnosis of cancer are also provided. |
| US10781264B2 |
PSMA and CD3 bispecific T cell engaging antibody constructs
The present invention provides bispecific antibody constructs of a specific Fc modality characterized by comprising a first domain binding to PSMA, a second domain binding to an extracellular epitope of the human and the Macaca CD3ε chain and a third domain, which is the specific Fc modality. Moreover, the invention provides a polynucleotide, encoding the antibody construct, a vector comprising this polynucleotide, host cells, expressing the construct and a pharmaceutical composition comprising the same. |
| US10781263B2 |
Anti-mesothelin immunoconjugates and uses therefor
The present invention provides immunoconjugates composed of antibodies, e.g., monoclonal antibodies, or antibody fragments that bind to mesothelin, that are conjugated to cytotoxic agents, e.g., maytansine, or derivatives thereof, and/or co-administered or formulated with one or more additional anti-cancer agents. The immunoconjugates of the invention can be used in the methods of the invention to treat and/or diagnose and/or monitor cancers, e.g. solid tumors, recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for the membrane-anchored, 40 kDa mesothelin polypeptide, which is overexpressed in several tumors, such as pancreatic and ovarian tumors, mesothelioma and lung cancer cells. |
| US10781261B2 |
Subcutaneous formulations of anti-CD38 antibodies and their uses
The present invention relates to subcutaneous formulations of anti-CD38 antibodies and their uses. |
| US10781255B2 |
Anti-CD83 antibodies and use thereof
The present disclosure relates to proteins that bind to CD83 and uses thereof, for example, in therapy, prophylaxis, diagnosis or prognosis. |
| US10781250B2 |
Refolding process for antibody's fragments
A refolding process of Ranibizumab is disclosed wherein the solubilized solution of heavy chain and/or light chain of Ranibizumab treated with refolding buffer under suitable conditions including pH, temperature and incubation period and the pH and temperature shift is performed at suitable interval to obtain high quality and quantity of refolded protein. |
| US10781249B2 |
Anti-GPC3 antibody
An object of the present invention is to provide: an anti-GPC3 antibody that recognizes an epitope different from that for existing antibodies (e.g., GC33 and GC199) and can specifically bind, even in the form of single chain antibody, to GPC3 localized on a cell membrane; CAR comprising the anti-GPC3 single chain antibody; an immunocompetent cell expressing the CAR; a gene of the anti-GPC3 antibody or a gene of the CAR; a vector comprising the anti-GPC3 antibody gene or the CAR gene; a host cell in which the vector has been introduced; a method for specifically detecting GPC3; and a kit for specifically detecting GPC3. An antibody comprising particular heavy chain CDR1 to CDR3 and particular light chain CDR1 to CDR3 defined in claim 1, and specifically binding to a human-derived GPC3 polypeptide specifically binds to GPC3 localized on a cell membrane. CAR-immunocompetent cells prepared on the basis of CAR comprising such single chain antibody are useful for cancer immunotherapy. |
| US10781248B2 |
α1-antitrypsin compositions and methods of treating autoimmune diseases
The specification provides compositions comprising chimeric proteins comprising AAT conjugated to an Fc region of an immunoglobulin. Methods for treating autoimmune disease, e.g., diabetes, e.g., Type 1 and Type 2 diabetes, are also provided. |
| US10781239B2 |
In vivo engineered cereblon protein
Disclosed herein are in vivo engineered cereblon protein and methods of making the same. The in vivo engineered cereblon protein can include a site-specific non-naturally occurring modification at cysteine 287 as set forth in SEQ ID NO:1, or cysteine 286 as set forth in SEQ ID NO:2 or 3, the modification comprising a moiety resulting from an in vivo Michael addition reaction between an exogenous Michael acceptor and the cysteine 287 as set forth in SEQ ID NO:1, or cysteine 286 as set forth in SEQ ID NO:2 or 3. |
| US10781238B2 |
Human-derived ferritin monomer fragment and fusion polypeptide using same
Disclosed are a human-derived ferritin monomer fragment and a fusion polypeptide using the same, and more particularly, to a human-derived ferritin of which a portion of a fourth loop and a fifth helix of the ferritin monomer fragment are removed, and a fusion polypeptide in which a polypeptide or a protein is fused to an N-terminus or a C-terminus of the ferritin monomer fragment. |
| US10781237B2 |
MSP nanopores and uses thereof
Provided herein are mutant single-chain Mycobacterium smegmatis porin (Msp) and uses thereof. |
| US10781226B2 |
Photoactivatable cancer prodrug
Described herein is photocaging methodology using ruthenium (II) complexes with 7-deazahypoxanthine-based anticancer agents. Specifically, 7-deazahypoxanthines are converted into photoactivatable chemotherapeutic agents for the controlled release of these toxic agents selectively into tumor tissue upon irradiation with light. |
| US10781224B2 |
Bis(oxymethyl)phosphinic acid and biogenic metal salts thereof as regulators of plant growth and development
The invention relates to agriculture, and specifically to regulators of plant growth and development that can be used for the pre-sowing treatment of cereal crop seeds and are in the form of bis(oxymethyl)phosphinic acid and biogenic metal salts thereof with the general formula (I) Men+[OP(O)(CH2OH)2]n, where n may be 1 or 2 and Me may be any of the following: H, Na, Ca, Mg, Co, Cu, Zn, Mn. The claimed compounds of formula I are effective regulators of plant growth and development when acting in concentrations of 1·10−7-1·10−12%. Pre-sowing treatment of the seeds of cereal crops, namely wheat, corn and rice, by means of the claimed compounds increases germination energy and germination capacity up to 13%, also increases plant vigor, and rootlet and shoot lengths increase up to 36%. Crop harvests increase and the quality of the resulting grain improves, which expands the range of effective, environmentally friendly plant growth and development regulators that act at the level of natural phytohormones. |
| US10781222B2 |
Surface treating agent including perfluoro(poly)ether-group-containing silane compound
A surface-treating agent including at least one perfluoro(poly)ether group containing silane compound of the formula (1): wherein each of symbols is as defined herein, wherein a number average molecular weight of the perfluoro(poly)ether group containing silane compound is 3000 or more and 6000 or less, and wherein 80 mol % or more of the perfluoro(poly)ether group containing silane compound contained in the surface-treating agent is a compound wherein g is 2 or more. |
| US10781219B2 |
Process for the preparation of (S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[F]imidazo[1,2-D][1,4]oxazepin-9-yl)amino) propanamide
Methods of making benzoxazepin oxazolidinone compounds as well as synthetic intermediates are described, including compound 18, having the structure: |
| US10781218B2 |
Substituted inhibitors of menin-MLL and methods of use
The present disclosure provides compounds of Formula (II-A), which inhibit the interaction of menin with one or more of MLL1, MLL2 and MLL-fusion oncoproteins. Also disclosed are methods for the treatment of leukemia, solid cancers, diabetes and other diseases dependent on activity of MLL1, MLL2, MLL fusion proteins, and/or menin. |
| US10781217B2 |
Imidazopyridazine compound
The present invention relates to an imidazopyridazine compound having cell growth inhibitory activity, and a pharmaceutical composition for preventing or treating cancer or a tumor including the same. The imidazopyridazine compound of Chemical Formula 1 according to the present invention has excellent cell growth inhibitory activity, and thus can be favorably used as a preventive or therapeutic agent for cancer or a tumor. |
| US10781215B2 |
Heterobicyclic compounds useful as modulators of IL-12, IL-23 and/or IFNα responses
Compounds having the following formula (I), or a stereoisomer or pharmaceutically-acceptable salt thereof, where all substituents are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition. |
| US10781211B2 |
Spirocycle compounds and methods of making and using same
Provided herein are spirocycle compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or ABHD6. Furthermore, the subject compounds and compositions are useful for the treatment of pain. |
| US10781205B2 |
Conjugates comprising RIPK2 inhibitors
The present invention relates to compounds, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, for example as inhibitors of the activity of RIP2 kinase, including degrading RIP2 kinase, the treatment of diseases and conditions mediated by the RIP2 kinase, in particular for the treatment of inflammatory diseases or conditions. |
| US10781204B2 |
TYK2 inhibitors and uses thereof
The present invention provides compounds of formula I, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders. |
| US10781203B2 |
Nontoxic compounds for the treatment and prevention of herpesvirus infections
Compositions for preventing or treating virus infections inhibit the biogenesis of cytoplasmic viral assembly compartment (cVAC). The preferred compounds are dihydroquinazolinones. |
| US10781200B2 |
Therapeutic inhibitory compounds
Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting plasma kallikrein. Furthermore, the subject compounds and compositions are useful for the treatment of diseases wherein the inhibition of plasma kallikrein inhibition has been implicated, such as angioedema and the like. |
| US10781198B2 |
Compound, resin, photoresist composition and process for producing photoresist pattern
A compound represented by the formula (I): wherein the values of R1, R2, R3, Ar and X1 in formula (I) are defined in the specification. |
| US10781197B2 |
Sulfonamide analogues of galiellalactone
Disclosed are sulfonamide analogues of galiellactone of formula (I) as STAT3-inhibitors for use in the treatment of a STAT3 signaling related disorder, e.g. solid cancers, hematological cancers, benign tumors, hyperproliferative diseases, inflammations, autoimmune diseases, graft or transplant rejections, delayed physiological function of grafts or transplants, neurodegenerative diseases and viral infections. The sulfonamide comprises a cyclic substituent. |
| US10781187B2 |
Benzotriazole derivative compound
Provided are benzotriazole derivative compounds of the general formula that are novel compounds capable of strongly absorbing light in the ultraviolet range, particularly 300-330 nm, while strongly absorbing light in the visible light short-wavelength range up to around 450 nm and being used suitably as a light absorber having high light fastness with a light-blocking function over an extended period of time. [Preferably, R1 is a hydrogen atom or alkyl group, R2 is a C1-8 alkyl group, R3 is a hydrogen atom, alkyl group, acryloyloxyalkyl group, or methacryloyloxyalkyl group]. |
| US10781181B2 |
N-((het) arylmethyl)-heteroaryl-carboxamides compounds as plasma kallikrein inhibitors
The present invention provides compounds of formula (I): (I) compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, U, D, E, W, X, Y and Z are as defined herein. |
| US10781180B2 |
3-phenyl-pyrazole derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto
The present invention relates to certain 3-phenyl-pyrazole derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the 5-HT2A serotonin receptor. Compounds and pharmaceutical compositions thereof are directed to methods useful in the treatment of platelet aggregation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, reducing the risk of blood clot formation, asthma or symptoms thereof, agitation or a symptom, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorder, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, and sleep disorders, sleep disorders, diabetic-related disorders, progressive multifocal leukoencephalopathy and the like. The present invention also relates to the methods for the treatment of 5-HT2A serotonin receptor mediated disorders in combination with other pharmaceutical agents administered separately or together. |
| US10781174B2 |
N-alkylaryl-5-oxyaryl-octahydro-cyclopenta[C]pyrrole negative allosteric modulators of NR2B
The present disclosure relates to N-alkylaryl-5-oxyaryl-octadihydrocyclopent[c]pyrrole negative allosteric modulators of NR2B receptors useful in the treatment of neurological diseases having the Formula I: where R1, R2, L1, L2, X, Y, and Y′ are described therein. |
| US10781173B2 |
Method for preparing apremilast
Provided is a method for preparing apremilast of formula I. Method one: (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine N-acetyl-L-leucine salt of formula II is reacted with 3-acetylaminophthalic anhydride of formula III in an aprotic solvent to produce the compound of formula I; method two: (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine N-acetyl-L-leucine salt of formula II is reacted with 3-acetylaminophthalic anhydride of formula III in an organic solvent in the presence of an organic alkali or an alkali metal hydride to produce the compound of formula I. The method for preparing apremilast requires inexpensive raw materials and reagents, is suitable for industrial production, and has great economic effects. |
| US10781171B2 |
Substituted pyrrolidines as G-protein coupled receptor 43 agonists
The present invention is directed to novel compounds of formula (I) and their use in treating and/or preventing metabolic diseases. |
| US10781170B1 |
Process for preparing Brivaracetam
A process for the preparation of Brivaracetam, an anti-convulsion drug, is provided comprising Hofmann rearrangement of (S)-3-(2-(chloroamino)-2-oxoethyl) hexanoic acid, followed by cyclization resulting in (R)-4-propyl-pyrrolidin-2-one which on condensation with bromo butyric acid or ester followed by reaction with ammonia results in Brivaracetam. |
| US10781166B2 |
Biocompositions for 3D printing
The present disclosure is directed to resins and to polymers, copolymers, and blends formed therefrom. |
| US10781165B2 |
pH-responsive amphoteric surfactant n-lauryl-(α-alkyl)-β-aminopropionic acid and preparation method and uses thereof
Disclosed are a pH-responsive amphoteric surfactant N-lauryl-(α-alkyl)-β-aminopropionic acid and a preparation method and uses thereof. An alkylamine and a solvent are added to a three-necked flask, stirred for complete dissolution, slowly dropwise added with methyl α-alkyl-acrylate and reacted at room temperature after the ice-water bath is removed. The reaction mixture is refluxed in water bath and evaporated under rotation to remove the solvent and the residual methyl α-alkyl-acrylate to give N-lauryl-(α-alkyl)-β-aminopropionic acid. Then N-lauryl-(α-alkyl)-β-aminopropionic acid and water are added to a three-necked flask, slowly dropwise added with a sodium hydroxide solution and reacted in water bath to give a crude product, which is filtered and dried to give a purified surfactant sodium N-lauryl-(α-alkyl)-β-aminopropionate. This surfactant is suitable for the foamed acid system and its performance can be switched by adjusting pH due to pH sensitivity. |
| US10781163B2 |
Process for preparation of O-Desmethyltramadol and salts thereof
A process of preparation of O-Desmethyl tramadol through potassium hydroxide mediated demethylation of Tramadol under phase transfer conditions. |
| US10781160B1 |
Hexadecyl Treprostinil crystals and methods for preparation thereof
There is provided stable crystalline Form I and Form II of Hexadecyl Treprostinil (C16TR) and processes for the preparation thereof. The stable crystalline Form I and Form II of Hexadecyl Treprostinil present advantages in storage, formulation, shipment and handling for commercially considerations. |
| US10781159B2 |
Hydrogenation method for increasing yield of cyclohexane-1,4-dicarboxylic acid diisooctyl ester
A hydrogenation method for increasing the yield of cyclohexane-1,4-dicarboxylic acid diisooctyl ester is provided. The hydrogenation method uses a hydrogenating reaction tank, which is equipped with a hollow-shaft gas-introducing mixer having air-extracting, air-exhausting and mixing functions, to allow hydrogen gas to be uniformly dispersed in a reaction solution. A ruthenium-on-alumina (Ru/Al2O3) hydrogenation catalyst can be used for carrying out a hydrogenation reaction under gentle conditions. Therefore, the hydrogenation catalyst can be used in a reduced amount, the risk of side reaction(s) can be reduced, and the yield of cyclohexane-1,4-dicarboxylic acid diisooctyl ester can reach at least 99% with a cis isomer proportion of at least 85.0%. The hydrogenation method shows extremely high economic benefit. |
| US10781158B2 |
Methods of protecting an organ using tetrahydrocurcumin and phosphatidylcholine
Pharmaceutical formulations of tetrahydrocurcumin and liposomes are described herein. The liposomes may comprise at least a first lipid, wherein the first lipid is a phospholipid or polyenylphosphatidylcholine are also disclosed. |
| US10781157B2 |
Process for preventing the deposition of polymers in a process for purifying (meth)acrylic acid
This invention produces technical (meth)acrylic acid without being confronted with problems of fouling of systems to purify the crude reaction mixture of (meth)acrylic acid synthesis, due to the presence of glyoxal formed during synthesis. The invention is based on the addition or generation of quinoline derivative in a glyoxal-containing (meth)acrylic acid flow in a quinoline/glyoxal derivative molar ratio ranging from 0.1 to 5, during the purification steps, said quinoline compound with one of formulas (I) or (II): wherein, groups R1, R2, R3, and R4 independently denote a hydrogen atom or a C1-C6, or R1 et R2 C-alkyl group combine and together with the atoms to which they are attached, form a saturated or unsaturated ring or heterocycle, preferably a phenyl group, and/or R3 and R4 combine and with the atoms to which they are attached, form a saturated or unsaturated ring or heterocycle, preferably a phenyl group. |
| US10781156B2 |
Compositions for improved production of acrylic acid
The present invention is directed to compositions which may undergo thermolysis to produce a higher purity acrylic acid product. In preferred embodiments of the present invention, the compositions comprise polypropiolactone and one or more active salts. The one or more active salts may catalyze thermolysis of the polypropiolactone so that the polymer depolymerizes into acrylic acid monomers. Certain concentrations of the one or more active salts result in higher purity acrylic acid products of thermolysis. In certain preferred embodiments, the one or more active salts include an acrylate group which may decompose under thermolysis to provide acrylic acid and thus decrease the concentration of undesirable contaminants in the acrylic acid product. In certain preferred embodiment, the one or more active salts comprise sodium acrylate. |
| US10781154B2 |
Processes for preparing calixarenes
This invention relates to a process for preparing a calixarene compound by reacting a phenolic compound and an aldehyde in the presence of at least one nitrogen-containing base as a catalyst to form the calixarene compound. The invention also relates to processes for high-yield, high solid-content production of a calixarene compound, with high selectivity toward a high-purity calix[8]arene compound, without carrying out a recrystallization step. |
| US10781149B2 |
Transalkylation process
Disclosed is a transalkylation process for making an aromatic material between a light aromatic material and a heavier aromatic material in the presence of hydrogen and a transalkylation catalyst comprising a hydrogenation component and a transalkylation component. The process comprises conducting the transalkylation reaction under conditions conducive to reducing the amount of cyclic compounds in the transalkylation reaction mixture in the beginning phase of the operation that is different from the conditions after the beginning phase. The invention is useful, e.g., in transalkylation between toluene and C9+ aromatic feed materials to produce xylenes and/or benzene. |
| US10781148B2 |
Method of preparing butadiene
A method of preparing butadiene and a device for preparing the same. The method includes passing reaction raw materials containing butene, oxygen, steam, and a diluent gas through an oxidative dehydrogenation reactor, and oxidative dehydrogenation is performed therein to produce a reaction product separating water from the reaction product condensing hydrocarbons to produce a crude hydrocarbon mixture; and separating butadiene from the crude hydrocarbon mixture, where a gas containing n-butane remaining after the butadiene is separated is fed into the oxidative dehydrogenation reactor, and butane is used as a diluent gas. Because butane is used as a diluent gas, a C4 mixture and gas products may be easily separated through cooling and condensation processes. Thus, the method may increase productivity while reducing energy consumption and raw material costs, thereby improving economic efficiency. |
| US10781145B2 |
Compositions for enhancing plant nutrient uptake and method of their use
Compositions and methods for enhancing nutrient uptake in plants are disclosed. The primary ingredients of the disclosed compositions are (a) poly amino acids, such as tri-polyaspartic acid (TPA), and (b) citric acid. Another component, (c) L amino acids may also be included in the composition. The composition may be used to enhance fertilizer efficiency and to promote plant growth and/or yield. |
| US10781142B2 |
Method of forming graphene/metal-oxide hybrid reinforced composites and product thereof
A graphene/metal-oxide hybrid reinforced composite and a method for a graphene/metal-oxide hybrid reinforced composite. The method includes freeze drying a slurry comprising graphene oxide and flakes to form a flake-graphene oxide foam. The graphene/metal-oxide hybrid reinforced composite comprises graphene, metal, and metal oxide nanoparticles. The metal is arranged in parallel lamellar structure to form metal layers in the composite. The metal oxide nanoparticles are present at the interfaces between the metal layers and the graphene. |
| US10781141B2 |
Composition for a novel grade for cutting tools
A hard metal composition of material comprised of, in weight percent, an alloy of from 6-15% of cobalt content; a molybdenum content of from 5-15% of the cobalt content and a chromium carbide content of from 0-15% of the cobalt content and the balance of tungsten carbide. |
| US10781138B2 |
Additive of cellulose nanofibrils or nanocrystals and a second polymer
A wellbore treatment fluid comprising: a base fluid; and an additive comprising: a first polymer bundle selected from the group consisting of cellulose nanofibrils, cellulose nanocrystals, and combinations thereof; and a second polymer, wherein the second polymer attaches to the first polymer bundle by a non-covalent mechanism. A method of treating a portion of a wellbore comprising: introducing the treatment fluid into the wellbore. |
| US10781132B2 |
Glass ceramics sintered body and coil electronic component
Provided is a glass ceramics sintered body including a glass phase and a ceramics phase dispersed in the glass phase, in which the ceramics phase includes alumina grains and zirconia grains, the glass phase includes an MO—Al2O3—SiO2—B2O3 based glass, in which “M” is an alkaline earth metal, and an area ratio of the alumina grains is 0.05 to 12% and the area ratio of the zirconia grains is 0.05 to 6% on the cross section of the sintered body. According to the invention, a glass ceramics sintered body, capable of a low temperature sintering having a low dielectric constant and a sufficient strength, and a coil electronic component using thereof can be provided. |
| US10781130B2 |
Heat treatment apparatus
A heat treatment apparatus includes: a furnace core tube made of silica glass; a heater provided adjacent to the furnace core tube, the heater heating a heating region; and a moving mechanism supporting a porous glass base material and relatively moving the porous glass base material with respect to the heater in the furnace core tube in a state where the heating region is heated by the heater to make the porous glass base material pass through the heating region. The heat treatment apparatus includes a thin-walled part provided in a region adjacent to a portion located in the heating region in the furnace core tube, the thin-walled part having a thickness of glass less than that of the portion located in the heating region. |
| US10781129B2 |
Fusing glass articles
A method of forming a glass article is provided. The method includes the steps of positioning a first interface surface of a first glass block proximate a second interface surface of a second glass block to define an interface seam, welding the first and second glass blocks together around a majority of the interface seam to define an internal cavity, coupling a vacuum fitting to at least one of the first and second glass blocks, drawing a vacuum in the cavity between the first and second glass blocks, and heating the first and second glass blocks to fuse the first and second glass blocks together. |
| US10781126B2 |
Burner for submerged combustion melter
The invention relates to a submerged combustion burner (1) and to a melter comprising submerged combustion burners (1). The burner comprises a substantially parallelepipedic body, the melt oriented face of which shows a longitudinal slot, two opposite walls of the slot comprising a series of nozzles each supplied separately with fuel and oxygen containing gas. The slot advantageously shows a narrow opening comprised between 10 and 30 mm, preferably between 15 and 25 mm, most preferably about 20 mm. The burner is advantageously made of steel plates, preferably high temperature resistant steel. The walls of the slot as well as the melt oriented face of the burner are advantageously cooled. According to the invention, the parallelepipedic burner body comprises a first external longitudinal volume showing a generally U-shaped cross-section and a second internal longitudinal volume fitted within the said first external longitudinal volume, showing also a generally U-shaped cross-section, one of the longitudinal volumes comprising a connection to a supply of oxygen and the other comprising a connection to a supply of fuel gas. The ends of the branches of the longitudinal volumes are connected to the burner nozzles. A flange is arranged around the parallelepipedic burner body at a distance from the melt oriented face of said body. |
| US10781124B2 |
Production method of self-fitting nano catalytic wastewater treatment agent
The method in the disclosure is achieved by chemically reacting diluted sulfuric acid generated when industrial sulfate titanium white powder production with a titanium raw material, and controlling an acid/titanium ratio and an iron/titanium ratio so as to produce the nano catalytic wastewater treatment agent. When being used for treatment of dyeing wastewater and other alkaline wastewater, by virtue of alkaline and dilution environment in wastewater, the nano catalytic wastewater treatment agent is subjected to self-fitting hydrolysist to produce a new ecological nano titanium dioxide ultrafine particle as a catalyst for decomposing organic matters in wastewater so as to decompose the organic matters into carbon dioxide and water; a decomposed and oxidized hydrated iron compound is used as a flocculation and adsorption nano particle, achieving the purpose of removing organic matters in wastewater. |
| US10781115B2 |
Apparatus and method for generating metal ions in a fluid stream
An apparatus for providing metal ions to a fluid waste stream includes a housing having an inlet port and an outlet port through which the fluid waste stream enters and exits the housing. Within the housing and between the inlet and outlet ports is an electrode assembly that includes first electrode ring assemblies and second electrode ring assemblies. Each first electrode ring assembly includes a first tubular section formed of electrically insulative material and has an interior through which the fluid waste stream flows. One or more first electrode plates span the interior of the first tubular section and contact the fluid waste stream. Each second electrode ring assembly includes a second tubular section formed of electrically insulative material and has an interior through which the fluid waste stream flows. One or more second electrode plates span the interior of the second tubular section and contact the fluid waste stream. The first tubular sections of the first electrode ring assemblies are in fluid communication with the second tubular sections of the second electrode ring assemblies. |
| US10781114B2 |
Electromagnetic pulsed-wave system for oil manipulation
A method is described for controlling an oil spill by seeding micron-sized magnetizable particles in the oil. Once seeded, particles can form a unique and preferential bond with the oil resulting in creation of a colloidal mixture. This bond forms as a result of a combination of forces including the intermolecular Van der Waal forces. Once this bond is formed, the oil is rendered magnetic and can be controlled and moved in response to a magnetic field. This can include removing oil from water, reducing the diffusion rate of oil on water, magnetically lifting oil from water or nonporous surfaces, as well as separating the magnetic material from the oil. |
| US10781113B2 |
System and method for purification of drinking water, ethanol and alcohol beverages of impurities
A system and method of the purification of drinking water, ethanol and alcohol beverages is based on the action of hydrodynamic cavitation processing of microbiological and chemical contaminants, micro particles and colloidal particles. The fluid flow moves at a high rate through a multi-stage cavitation device and filtration module to generate hydrodynamic cavitation features in the fluid flow. The cavitation features generate changes in the velocity, pressure, temperature, chemical composition and physical properties of the liquid. The cavitation features also prevent the deposition of contaminants upon and remove contaminants from the surface of the filter module, reduce the load on the filter elements and increase the life of the filter module. |
| US10781109B2 |
Iron oxyhydroxide nanodispersion liquid
It is an object of the present invention to provide a nanodispersion liquid of iron oxyhydroxide that is stable and does not contain components derived from auxiliary components. The nanodispersion liquid of iron oxyhydroxide according to the present invention is a nanodispersion liquid in which particles comprising iron oxyhydroxide as a main component and having an average particle diameter d50 of 0.2 μm or less and a d90 of 1 μm or less are dispersed in a solvent. The iron oxyhydroxide is preferably β-iron oxyhydroxide. The nanodispersion liquid of iron oxyhydroxide according to the present invention preferably contains no other components than a substance derived from at least either of an iron compound and a base, a pH adjusting agent, and a solvent. |
| US10781108B2 |
Sheet containing two-dimensional hydrogen boride and production method for sheet containing two-dimensional boron compound
A two-dimensional hydrogen boride-containing sheet of the present invention has a two-dimensional network that consists of (HB)n (n≥4). |
| US10781106B2 |
Method for separating detonation nanodiamonds
Disclosed is a method for separating nanodiamond clusters synthesized by a detonation method having a size of 100 nm˜1,000 nm into nanodiamonds of 100 nm or less—more specifically, into uniformly sized nanodiamonds in the range of 5 nm˜50 nm, free of metal and alkaline impurities and ready to quantitatively attach functional groups on the surface of the nanodiamonds for applications such as thin film precursor materials, drug delivery systems and cosmetics compositions. |
| US10781103B2 |
Microwave reactor system with gas-solids separation
Microwave chemical processing system having a microwave plasma reactor, and a multi-stage gas-solid separation system are disclosed. The microwave energy source has a waveguide, a reaction zone, and an inlet configured to receive the input material, and the input material is converted into separated components. The separated components include hydrogen gas and carbon particles. The multi-stage gas-solid separation system has a first cyclone separator to filter the carbon particles from the separated components, and a back-pulse filter system coupled to the output of the first cycle separator to filter the carbon particles from the output from the first cyclone separator. |
| US10781099B2 |
Metered acid acceleration of hydrogen generation using seawater as a reactant
An underwater hydrogen generator can include a watertight reaction housing enclosing a metering chamber. The metering chamber can have an upper portion that terminates at a piston opening, and a lower portion that merges into a funnel, which can further terminate at a metering opening. The metering chamber can be filled with an acid accelerator, and the watertight reaction void can be partially filled with NaBH4 in solution. The generator can further include a seawater float valve that can be in fluid communication between the external environment, the metering chamber and the void defined by the reaction housing. The float valve, metering chamber and reaction housing can cooperate to generate hydrogen when said generator is submerged, by allowing seawater to contact both the acid accelerator and the NaBH4. The size of the metering opening can determine the rate at which acid accelerator is added to the NaBH4 solution. |
| US10781094B2 |
Pressure sensor assembly mounted to a ceramic substrate
A pressure sensor assembly includes a sensor die and a ceramic substrate. The sensor die has a first side and a second side that is opposite to the first side. The sensor die includes a silicon chip that has a diaphragm configured to be exposed to a working fluid. The sensor die includes one or more electrical sensing elements mounted on the diaphragm and configured to measure a pressure of the working fluid. The sensor die is mounted to the ceramic substrate via a solder layer that engages the ceramic substrate and the second side of the sensor die. |
| US10781092B2 |
Decanter
A decanter arranged to permit storage of wine or other beverage while isolated from ambient air and employing a variable size beverage storage volume. A valve may control flow past a piston as the piston is moved relative to a container to adjust a size of the beverage storage volume. |
| US10781085B2 |
Winch including integrated contactor and motor
Methods and systems are provided for a winch including a motor and a contactor assembly positioned within a same housing. In one example, the contactor assembly is positioned at an end of an armature of the motor and may include a controller configured to control winch component operation. The contactor assembly is electrically coupled to the armature via a plurality of electrically conductive brushes. |
| US10781083B2 |
Mobile crane and method for angling a main boom extension in relation to a main boom of a mobile crane
A mobile crane comprising a main boom, which is supported on the mobile crane in such a way that the main boom can be rocked and which can be put upright by means of an elevating cylinder, and a main boom extension, which is releasably connected to a main boom head of the main boom by upper and lower pins. The main boom extension, proceeding from a home position, can be angled in relation to the main boom about a rocking axis by means of an angle drive after the upper pins have been released, which angle drive acts on a base of the main boom extension, where a drive of the mobile crane provided for a different task provides the kinetic energy for the angle drive. The angle drive is designed in such that a telescoping cylinder of the main boom provides the kinetic energy for the angle drive. |
| US10781080B2 |
Overhead travelling crane
An overhead travelling crane having a horizontally extending crane girder, which can be displaced in a railbound manner along a craneway, and having a crane trolley, which can be displaced along the crane girder and carries a lifting gear for raising and lowering a load. The lifting gear has a suspension structure formed as a cable or chain and the overhead travelling crane has electric drives for movements of the overhead travelling crane. The overhead travelling crane has an energy store connected to the drives to supply the drives with energy. |
| US10781077B2 |
Solution for displacing an elevator car
An apparatus for displacing an elevator car from its pathway includes a rotational vehicle configured to rotate around an axis of rotation and at least one guide rail section mounted with the rotational vehicle along, which at least one guide rail section the at least one elevator car is arranged to travel. The at least one guide rail section is mounted substantially parallel to the axis of rotation of the rotational vehicle. The rotational vehicle is configured to rotate 90 degrees. An elevator system is also disclosed. |
| US10781075B2 |
Emergency safety actuator for an elevator
A device for a friction force provider for an emergency safety actuator for an elevator is disclosed. The friction force provider may include a housing having a first end and an opposing second end, where the first end may define an opening. The friction force provider may further include a primary magnet positioned within the housing and configured to move between an armed position and a working position. The primary magnet may be configured to create a force on a rail of an elevator system in the working position and be held within the housing in the armed position. |
| US10781074B2 |
Elevator car movement monitoring device, assembly device and assembly method for an elevator system
A monitoring device for an elevator system is used with an assembly device for assembling a shaft retrofit and a method for monitoring an assembly platform. The monitoring device monitors movements of an elevator car and includes a sensor system for detecting a movement variable and at least one analysis device that evaluates the detected movement variable and compares it to a threshold. If the threshold is exceeded, a signal output is triggered to actuate a brake/catching device. The monitoring device selects the threshold from specified thresholds based on a state of the monitoring device. The specified thresholds include at least one normal operation threshold, and the monitoring device indicates a normal state as soon as specified connection elements are connected to it. The monitoring device further contains a checking routine for determining a state of the monitoring device, and selects the threshold from specified thresholds based on the state. |
| US10781071B2 |
Protective insert
A protective insert for protecting e.g. coils or rolls of sheet steel or aluminum is disclosed. The protective insert is open and diametrically adjustable. The ends of the protective insert may be adjustably engaged by means of engagement means. The engagement means permit diametrical adjustment and locking of the diameter of the protective insert to a suitable diameter. A method of protecting a portion of an object, in particular a roll of sheet material, having a hollow core, is also disclosed. |
| US10781069B1 |
Turntable pay-out organizer for coils and spools
A stackable apparatus for mounting and feeding coiled or spooled wire or cable includes a turntable having a plurality of posts that are length adjustable and positioned in a track, respectively, and configured to guide a coil or receive the spool. Each post includes a post slide portion correspondingly shaped to slide along the track. The apparatus includes a base having a pair of support members each having a longitudinal configuration fixedly attached to one another in a transverse arrangement so as to form conjoined members, the conjoined members defining a bore. A hub in the form of a lazy susan is received in the bore and operable to receive a post depending from the turntable for providing freewheeling rotation of the turntable. |
| US10781064B2 |
Method for applying air to sheets stacked on sheet stacking apparatus
A sheet stacking apparatus includes a stacking unit on which a sheet bundle is to be stacked, a lifting unit that can lift and lower the stacking unit, and an air blower unit that can apply air to a side face of the sheet bundle via an air blowing port. The stacking unit further includes a stacking face that comes into contact with and holds a lowermost sheet of the sheet bundle, and a support portion that supports a portion of the stacking face near an end portion thereof, and has a face that is not parallel to the stacking face. The support portion includes a ventilating portion that allows air blown out by the air blower unit from a portion of the air blowing port to pass through the ventilating portion, the portion of the air blowing port being below the stacking face. |
| US10781058B2 |
Palletiser for loading and packaging unstable containers
The innovation disclosed herein is an improved palletiser for loading and packaging unstable articles, such as plastic, glass, steel, aluminium, etc. containers onto a pallet for bulk storage and/or transport. The innovation includes a pallet station having a pallet housing that receives pallets, a layer pad store substantially aligned with the pallet housing, a container lifting sub-assembly that receives a predetermined row of containers, a pusher assembly that urges the predetermined row of containers onto a pallet, and a layer pad transfer assembly. |
| US10781056B2 |
Adaptive apparatus and system for automated handling of components
Various adaptive apparatus and systems for automated handling of components such as composite plies are provided. In one embodiment, a ply manipulation system is provided that comprises an automated machine having an arm, and a ply manipulation tool attached to the arm of the automated machine. The ply manipulation tool includes a first shuttle including a first gripper, a second shuttle including a second gripper, and an actuator. The ply manipulation system further comprises a processor that automatically controls the actuator to move the first and second shuttles linearly with respect to one another to adapt the first and second grippers to a ply shape. In another embodiment, the first and second shuttles include one or more clamping elements moveable to a position to be deployed outside a perimeter of the ply. Methods for removing a ply from a sheet of material using a ply manipulation tool also are provided. |
| US10781055B1 |
System and method for separating packages of different sizes
A system for separating packages of different sizes includes a conveyor segment and a plurality of alignment members dividing the conveyor segment into a plurality of conveyor lanes. The conveyor segment has an input end, a discharge end and transport mechanism for transporting packages from the input end to the discharge end. The transport mechanism is configured to impart a lateral shift to packages on the conveyor segment. One or more of the alignment members each forms a respective window to allow lateral shifting of packages across adjacent conveyor lanes. Each window has a uniquely defined vertical height to the limit lateral shifting of packages across adjacent conveyor lanes based on a height of each package. Each conveyor lane delivers packages of a uniquely different size group at the discharge end of the conveyor segment. The packages in a conveyor lane are aligned against a respective alignment member. |
| US10781053B1 |
Control system for automated singulation system
A control system for an automated singulation system is provided. The control system detects a presence of a first item on a first conveyor and detects a presence of a second item on a second conveyor while the first item is present on the first conveyor. The second conveyor transfers items onto the first conveyor and is at a lower height than the second conveyor. The first conveyor is oriented perpendicularly with respect to the second conveyor. In response to detecting the presence of the second item, a location of the first item along a length of the first conveyor is determined. The first conveyor and the second conveyor are controlled based at least on the location of the first item. |
| US10781050B2 |
System and method for processing of optical lenses
A system and a method for processing of optical lenses in which the processing takes place by means of different processing apparatus between which there is a respective transfer apparatus. The transfer apparatus are used both for longitudinal and also cross conveyance. Each processing apparatus has its own conveyor apparatus which is controlled by the processing apparatus itself. The transfer apparatus are controlled by a central transfer control. |
| US10781048B2 |
Method for operating a conveyor system
A method for operating a conveyor system for objects, in which a conveyor apparatus is present at an operating site and is operated with a plurality of conveyor carts each having at least one fastening device for at least one object. The number of conveyor carts available at the operating site for operating the conveyor apparatus for a process sequence defines an actual number; the number of conveyor carts needed at the operating site to operate the conveyor apparatus for the process sequence defines a target number. The difference between the actual number and the target number defines a required number if the actual number is less than the target number, or defines an excess number if the actual number is greater than the target number. A conveyor cart pool is provided and comprises a stock number of conveyor carts, at least some of which are stored at a pool site which differs from the operating site of the conveyor apparatus. A number of conveyor carts corresponding to the required number is physically transferred from the conveyor cart pool to the operating site, as a result of which the actual number is increased by the required number and the stock number is reduced by the required number, or a number of conveyor carts corresponding to the excess number is assigned to the conveyor cart pool, as a result of which the actual number is reduced by the excess number and the stock number is increased by the excess number. |
| US10781037B2 |
Roof for a modular shipping container
A roof for a modular shipping container is provided. The modular shipping container includes a first end wall, a second end wall, a first side wall, and a second side wall. The roof includes a roof sheet having a top surface and defining a first end, a second end, a first side, and a second side. The roof further includes a pair of skid plate assembles. One of the pair of skid plate assembles is arranged along the first side of the roof sheet, and the other of the pair of skid plate assemblies is arranged along the second side of the roof sheet. The pair of skid plate assemblies partially extend over the top surface of the roof sheet. The roof sheet is formed of a unitary piece of material. |
| US10781033B1 |
Reusable bottle package
A reusable bottle package includes an inner bottle, an inner base coupled to the inner bottle, an outer bottle, an outer base coupled to the outer bottle, and a push-to-release button contained by the outer base. The outer base cooperates with the inner base to form at least one snap feature. The inner bottle is secured to the outer bottle when the at least one snap feature is engaged. The at least one snap feature becomes disengaged when the push-to-release button is depressed, thereby allowing the inner bottle to be removed from the outer bottle. |
| US10781032B2 |
Tire sealant dispenser
A tire sealant dispenser matches with an air compressor and contains a body in which chemical fluid (such as tire sealant) is filled, a cap connected on an opening of the body, a drive element configured to urge a punch element to pierce a film, such that an air conduit is in communication with a sealant conduit, pressurized air flows into the body via the air conduit from the air compressor, and the chemical fluid flows out of the sealant conduit. |
| US10781027B2 |
Packaging system for oxygen-sensitive drugs
Described herein are pharmaceutical packaging systems which prevent oxidative degradation of oxygen-sensitive drugs, such systems including a primary packaging container with an oxygen permeable component, a secondary packaging with very low permeability to oxygen and an oxygen absorber. |
| US10781026B2 |
Container and package
To provide a container and a package configured to prevent a deformation of housed metal. According to one aspect of the present invention, there is provided the container. This container includes a cylindrical container body, a lid, and a flat plate-shaped inner plug. The cylindrical container body with a bottom has a sidewall and a bottom wall. The lid has a flat plate portion and a side portion. The flat plate portion covers an opening of the container body. The side portion covers at least a part of an outer peripheral surface of the container body. The flat plate-shaped inner plug is located inside the lid. The container body includes a thread ridge on the outer peripheral surface. The side portion of the lid has a screw groove with two or more threads on its inner peripheral surface. The lid is configured to be screwed with the container body by screwing the screw groove with the thread ridge. A plurality of lock portions are disposed on an outer periphery of the lid. The screw groove has the threads by a count identical to a count of the lock portions. The inner plug is held to an inside of the lid by each of the lock portions fitted into each inside of the screw grooves. |
| US10781025B2 |
Fibrous substrate containing fibers and nanofibrillar polysaccharide
A single-layer fibrous substrate comprising, by dry weight compared with the weight of the substrate: between 39.9 and 87.9% natural fibers refined to above 50° SR; between 12 and 60% nanofibrillar polysaccharide; and between 0.1 and 4% of at least one retention agent. |
| US10781024B2 |
Method for vacuum packing high-purity tin and vacuum-packed high purity tin
Provided is a high-purity tin product that does not contain undesirable carbonaceous impurities as a result of the following: a vacuum-packed high-purity metal article (vacuum-packed high-purity tin article) is obtained by vacuum packaging a high-purity metal (high-purity tin), at least a portion of a surface of a high-purity metal being covered with a fluorocarbon resin sheet; and the vacuum-packed high-purity metal article(vacuum-packed high-purity tin article) is obtained by vacuum packaging, with a vacuum packaging film, the high-purity metal in which at least a portion of a surface is covered with the fluorocarbon resin sheet. |
| US10781022B2 |
Easy opening packaging article made from heat-shrinkable film exhibiting directional tear
A heat-shrinkable packaging article has one or more tear initiators for initiating a manual tear that can be propagated to open a package and allow a product to be readily removed therefrom, without the use of a knife or scissors or any other implement. The tear initiators are present in a skirt and/or header of the article. The skirt and/or header has a first side and a second side. In one embodiment, some or all of the first side of the skirt and/or header can be heatset in order to reduce the shrink and curling of the skirt and/or header. This improves identification and utilization of the tear initiators by a consumer upon shrinking the packaging article around the product. In another embodiment, the skirt and/or header has a plurality of pairs of tear initiators to allow portions of the package to be torn off to expose a portion of the product that can then be sliced off while the remainder of the packaged product remains covered by a remainder of the film. |
| US10781021B2 |
Systems and methods for a cord holder
An apparatus for securing items includes a twist tie and a stretchable end for the twist tie, the stretchable end molded around the twist tie. The stretchable end includes an aperture, a narrow slit in the stretchable end. In one configuration, the aperture may stretch wider and longer than a starting shape. The stretchable end is made of Thermoplastic Elastomer (TPE) and has a durometer between 30 and 100 shore A. |
| US10781015B2 |
Member coupling mechanism
A member coupling mechanism capable of coupling two members using a necessary tightening force even in a limited space by a small and simple configuration. A member coupling mechanism includes a first member including a member coupling portion having an open apical surface, a second member coupled to the member coupling portion of the first member, an elastic sealing member inserted between the first member and the second member to seal an opening of the apical surface of the member coupling portion, a coupling member that couples the first member and the second member together, and an acting portion that exerts a force on the coupling member. |
| US10781014B2 |
Hinged slider for a closure assembly
A hinged slider for a closure assembly of a bag includes a top wall and a pair of legs extending from the top wall. A first leg and a second leg of the pair each includes a top end attached to the top wall and a bottom end opposing the top end. A pair of wings is hingedly attached to the pair of legs. A first wing and a second wing of the pair of wings is each hingedly attached to the bottom end of the first leg and second leg, respectively, as a hinge mechanism. The first wing and the second wing hinge downwardly in order to install the slider onto the closure assembly. |
| US10781013B2 |
Storage system having stackable and engageable vessels
A storage system includes a plurality of vessels each shaped to engage with an adjoining vessel in a top-to-bottom orientation. The volume of the vessels may vary. The lip of each vessel includes a plurality of radially positioned flanges, and the bottom of each vessel includes a plurality of radially positioned locking lugs that correspond and engage with the flanges upon rotation of one vessel relative to the other. |
| US10781009B2 |
Systems, apparatuses, and methods for marking a moving film and methods of manufacture and use of metallized marked films made therefrom
Systems for marking a moving film that include a triggering apparatus (140) that repeatedly provides a trigger signal, a controller (120) that receives the trigger signal and generates a marking signal, and a marking device (130) that receives the marking signal and marks the film are provided Also provided are methods for marking a moving film that employ the systems. Apparatuses for marking a moving film that include the triggering apparatus and the controller are also provided. Methods for making metallized marked films that include a film marked by these systems and a metallized layer, in which at least one marking is embedded within the film are also provided. Also provided are methods for making packages and packing a product in these packages, in which the packages include the metallized marked films are also provided. |
| US10781004B2 |
Bag making and packaging machine
A bag making and packaging machine includes a cutter fixed to a sealing member that cuts a laterally sealed portion of a film using pressure force with which a pair of sealing members sandwiches the film during lateral sealing. The bag making and packaging machine further includes a pair of sealing jaws, a knife, a pressurization mechanism, and a pressurization mechanism control part. The knife fixed to one sealing jaw, fusion-cuts the laterally sealed portion of the film. The pressurization mechanism exerts pressure force on one sealing jaw towards the other sealing jaw so that the pair of sealing jaws sandwiches and laterally seals the film therebetween, and the knife comes into contact with a laterally sealed portion and fusion-cuts the laterally sealed portion. The pressurization mechanism control part causes the pressurization mechanism to cease exerting pressure force based on error information pertaining to the film or the goods. |
| US10781003B2 |
Method, system, and apparatus for pharmaceutical container filing and lyophilizing
In one general aspect, a method is disclosed for processing a pharmaceutical substance in a pharmaceutical processing system that includes lyophilizing a plurality of containers provided in a nest. A first controlled environment enclosure in the pharmaceutical processing system is isolated against an external environment, and a controlled environmental condition is established in the first controlled environment enclosure. The pharmaceutical substance is deposited into at least a portion of the plurality of containers in the first container nest at a filling station within the first controlled environment enclosure. The deposited pharmaceutical substance is lyophilized in the first container nest. |
| US10780998B1 |
Spacecraft design with multiple thermal zones
A spacecraft includes a body, a plurality of separate units, and a first auxiliary radiator panel. The body includes a plurality of sidewalls, at least a first sidewall of the plurality of sidewalls including an outboard-facing radiator surface having optical solar reflectors disposed thereon. A first subset of the plurality of units is thermally coupled with the outboard-facing radiator surface of the first sidewall. A second subset of the plurality of units is thermally coupled with the first auxiliary radiator panel and is isolated from at least conductive thermal heat transfer with the outboard-facing radiator surface of the first sidewall. The first subset of units is spatially proximate to the second subset of units and is configured to operate in a first temperature range. The second subset of units is configured to operate in a second temperature range, the second temperature range being different from the first temperature range. |
| US10780997B1 |
Systems and methods for shock-resistant memory devices
A shock-resistant memory device comprises a housing and a memory module. The memory module is disposed within the housing and surrounded by potting material to protect the memory module from damage during a shock event. The housing can include a port that accommodates a data connection between the memory module and a sensor from which data is desirably received by the memory module. During a shock event the connection between the memory module and the sensor may be severed, but data stored in the memory module can be retained in the memory module which is protected by the housing. To facilitate retrieval of the memory device subsequent to a shock event, a balloon can be affixed to the housing. The balloon can be configured to inflate subsequent to the shock event so that the shock-resistant memory device does not sink in water and to make the memory device more visible for recovery. |
| US10780995B1 |
System and process for providing helicopter instruments on a tablet in digital form during external load operations
A system providing helicopter instruments on a tablet in digital form for external load operations is disclosed. The system includes a data collect system/device that retrieves data from the drive train of the helicopter and wirelessly transmits the data to a tablet computing device with a tablet app running to visually output gauges and real-time operational helicopter readings so as not to exceed operating limits when the pilot is out of a line of sight of the instrument panel in the helicopter, such as when engaged in external load operations. The system and tablet app implementation supports many different helicopter variants and the tablet is easily mounted in any helicopter or moved from one helicopter to another. |
| US10780992B1 |
Mobile emergency landing pad
An emergency landing pad is used to capture a vertical landing capable aircraft that has a hung gear. The device is trailer based with the trailer having a series of wheels. At least one capture pad sits atop the trailer so that a portion of the aircraft lands atop the capture pad which cushions the fuselage of the aircraft. The capture pad is made from a resilient material, such as high-density foam, a rubber or similar materials. A cover is placed over the capture pad and one or more straps cinches the capture pad and the cover to the trailer. The cover may have markings on an outer surface thereof, which markings may be light reflective. The trailer is towed to the landing site via an ordinary tug and several trailers can be chained together in series in case more than one trailer is needed for aircraft capture. |
| US10780991B1 |
Aircraft winglet light assembly
An aircraft winglet light assembly is disclosed. The aircraft winglet light assembly includes an exterior skin coupled to an aircraft winglet of an aircraft. At least one interior surface of the exterior skin defines a cavity within the exterior skin. The aircraft winglet light assembly further includes one or more illumination sources housed within the cavity. The aircraft winglet light assembly further includes one or more sets of holes within the exterior skin. The one or more sets of holes are configured to allow illumination generated by the one or more illumination sources to pass through the exterior skin. The aircraft winglet light assembly further includes one or more protection elements proximate to the one or more sets of holes. |
| US10780988B2 |
Propeller safety for automated aerial vehicles
An automated aerial vehicle (AAV) and system for automatically detecting a contact or an imminent contact between a propeller of the AAV and an object (e.g., human, pet, or other animal) are described. A safety profile for the AAV may be selected based on various factors including a position or configuration of the AAV. When a contact or an imminent contact is detected, the selected safety profile may be executed to reduce or avoid any potential harm to the object and/or the AAV. For example, if a contact with a propeller of the AAV by an object is detected, the rotation of the propeller may be stopped to avoid harming the object. Likewise, an object detection component may be used to detect an object that is nearing a propeller, stop the rotation of the propeller, and/or navigate the AAV away from the detected object. |
| US10780974B2 |
Passively folding propeller blades for drag reduction
A propulsion unit includes a motor rotor that spins about a central rotational axis, propeller blades each having a proximal base and a distal tip, and pivot mounts each coupling the proximal base of a corresponding one of the propeller blades to the motor rotor. The propeller blades each freely pivot at the proximal base about a corresponding offset pivoting axis that is substantially parallel to but offset from the central rotational axis of the motor rotor. |
| US10780972B2 |
Outboard durable transparent conductive coating on aircraft canopy
A coated transparency including an electrically conductive multilayer stack is disclosed. The electrically conductive multilayer stack includes a first metal oxide layer including aluminum doped zinc (AZO), a metal layer including gold, and a second metal oxide layer including AZO. The electrically conductive multilayer stack has a low sheet resistance to provide radar attenuation and anti-static or static-dissipative properties, and has greater flexibility and resistance to corrosion than conventional multilayer stacks used to coat aircraft canopies and other substrates. |
| US10780969B2 |
Propulsion system for a buoyant aerial vehicle
A buoyant aerial vehicle includes: a balloon configured to store a gas; a payload coupled to the balloon; and a propulsion unit coupled to the payload by a tether. The propulsion unit includes: a fuselage having a substantially longitudinal shape, a first end, and a second end; a primary airfoil coupled to the fuselage; a secondary airfoil coupled to the fuselage at one of the first end or the second end; and a thrust generating device disposed at one of the first end or the second end and configured to move the propulsion unit relative to the payload along a propulsion flight path. The movement of the propulsion unit imparts movement of the buoyant aerial vehicle along a vehicle flight path. |
| US10780965B2 |
Quarter-twist pedal propeller
A quarter-twist pedal propeller includes a propeller blade and a support frame. A large synchronous wheel is mounted on an upper part of the support frame through a main shaft, a pedal assembly is mounted on each end of the main shaft. A small synchronous wheel is mounted on a lower part of the support frame through a secondary shaft. A waterproof plate is mounted outside the support frame. The waterproof plate is disposed above the propeller blade. A portable cover that covers the large synchronous wheel is provided on top of the support frame. A grabbing part is provided on the portable cover. A balancing pole is transversely connected to the portable cover. The present invention is practical and cost-effective, has novel and simplified structure, and can reduce power loss due to multiple transmissions. It is convenient during pedaling. |
| US10780962B2 |
Ventilation system
System for emergency ventilation of an underwater environment (dry); the system includes a supply device to supply air; a capsule to be immersed in water to a depth of at least 60 meters; a duct to fluidically connect the power device to the capsule; a duct in order to fluidically connect the capsule to the underwater environment; a duct to fluidically connect the underwater environment to the capsule; a compressor to discharge the gas, arriving in the capsule from the underwater environment, in water at a depth of at least 60 meters. |
| US10780960B2 |
Electronic device for diving equipment
The device (50) includes at least one electronic circuit (52) and a battery (53) provided for powering the circuit, wherein the circuit and the battery are included in a block of hydrophobic material, for example a block of resin (51). The battery is, for example, an inductively charged battery and the device can include optical sockets (56a, 56b, 56c) for fiber-optic cables, so as to avoid all contact of metal parts with water. Such a device is especially suitable for a buoyancy compensator vest, for use as a “stabilizer during immersion” and as a “closed-circuit rebreather”. |
| US10780949B2 |
Power boost regulator
A power generation system is provided including a power boost regulator operative to provide load matched voltage operation of an AC power source. |
| US10780947B2 |
Automatic return structure for chain detachment of bicycle
In an automatic return structure of a bicycle, a stopper block is mainly disposed on the other end of a crank different from a pedal, and a guide block is disposed on an inner surface of a middle portion of the crank. The stopper block may be formed with a groove on the other end of the crank. The guide block has an arced guide surface. Upon chain detachment, the stopper block blocks the chain, and then the pedal being pedaled makes the guide block lift up the chain to a location above the sprocket, so that the chain slides downward to teeth of the sprocket along the arced guide surface to perform automatic upshifting. The danger of chasing caused by the sudden slowdown or stop upon chain detachment can be avoided, the rider needs not to get off to perform manual upshifting, and riding convenience can be significantly enhanced. |
| US10780941B2 |
Steering assembly for a motorcycle having a continuously variable transmission
Provided is a motorcycle including a frame, a front ground-engaging wheel, rear ground-engaging wheel and a steering assembly. The steering assembly includes handlebars, an upper steering stem, a lower steering stem and a lever assembly intermediate the upper steering stem and the lower steering stem and wherein the steering assembly is operably connected to the front ground-engaging wheel. |
| US10780940B2 |
Human-powered vehicle control device
A human-powered vehicle operating device including a base member, a first operating member, a second operating member, a first electrical switch and a second electrical switch. The first operating member includes a first operating surface and configured to pivot about a first axis with respect to the base member. The second operating member includes a second operating surface and configured to pivot about a second axis with respect to the base member. The first electrical switch is provided between the base member and the first operating member. The second electrical switch is provided between the base member and the second operating member. The first operating member and the second operating member are arranged next to each other in a first direction and configured to pivot independent from each other. |
| US10780937B2 |
Frame structure for a motorcycle
A frame structure for a motorcycle includes a main frame for supporting a front structure of the motorcycle, the main frame including a pair of main pipes extending rearward from a head pipe of the front structure; a pivot bracket including a metal plate, the pivot bracket connected to the main frame and including a rear cushion mounting portion and a swing arm mounting portion for swingably mounting a rear cushion and a swing arm. The main frame further includes: a pair of support pipes extending rearward from the head pipe for supporting the front structure; and a connecting portion jointly connected at a rear end of the pair of main pipes and the pair of support pipes for connecting to the pivot bracket. The rear cushion mounting portion is positioned forward of the connecting portion of the main frame when viewed from a side view of the motorcycle. |
| US10780934B2 |
Seat rod clamp assembly and vehicle
A seat rod clamp assembly and a vehicle is described. The seat tube clamp assembly includes an annular hoop having a notch, the annular hoop having a locking portion on each side of the notch, and the annular hoop having a post hole. The seat tube clamp assembly includes a wrench rotatably connected to the two locking portions, and at least one pair of eccentric washers, such that one of the eccentric washers is fixed to one of the locking portions, the other of the eccentric washers is correspondingly fixed to the wrench, an end surface of each of the eccentric washers has an inclined surface, and the end surfaces of the two eccentric washers are abutted against each other. |
| US10780928B2 |
Electric vehicles, electric vehicle systems and methods of control
Electric vehicles, electric vehicle systems, and methods for controlling the electric vehicles or electric vehicle systems are described. In one implementation, an electric vehicle includes a main body for carrying a user, a plurality of electric wheels mounted on the main body, and a controller mounted on the main body. The main body includes a front main body and a rear main body removably connected to the front main body. The front main body can move independently when disconnected from the rear main body. In some embodiments, at least one of the plurality of electric wheels is mounted on the front main body. The controller is configured to send drive signals to the plurality of electric wheels according to input of the user. The plurality of electric wheels are configured to rotate according to the drive signals. The electric vehicles and the electric vehicle systems described in the present disclosure have a separable main body, advantageously allowing for short or medium distance transportation at low cost, flexibility in turning, and great potential for expanding their functionality. |
| US10780927B2 |
Spoiler apparatus for use with vehicles
Spoiler apparatus for use with vehicles are disclosed. A disclosed spoiler for a vehicle includes a sensor operatively couple to the vehicle. The spoiler also includes a body supporting the sensor and including an aperture positioned thereon. The body is coupled to an exterior vehicle surface near a lamp of the vehicle, separate from the spoiler, such that the lamp is exposed via the aperture. |
| US10780921B2 |
Vehicle frame structure
A vehicle frame structure includes a pair of side rails extending along the length of a vehicle, and outriggers coupled to the side rails, respectively, to protrude further outward in the vehicle width direction with respect to the corresponding side rails. The outrigger includes a cab mounting bracket joined to the side rail. The cab mounting bracket includes a rear end side that is inclined inward in the vehicle width direction as it goes rearward. The cab mounting bracket further includes, in the middle of the rear end, a bent portion which is bent to have a convex shape toward the front of the vehicle. |
| US10780917B2 |
Steering systems, steering and speed coordination systems and associated vehicles
In a broad respect, vehicles that are capable of making a low- to zero-radius turn using the independent rotation of drive wheels and by turning the non-driving steerable structure or structures (such as wheels) with a steering input device (in some embodiments, the driving wheels also may be capable of being turned). This may be accomplished using a steering system, a speed control system and an integration device (together, a control system) that are configured to work together to provide correct steering in forward and reverse, and, in some embodiments, to reduce the speed of the outboard drive wheel of the vehicle when it enters an extreme turn under constant speed input. Different systems configured for use in such vehicles are included. |
| US10780912B2 |
Steering device
A steering device includes: a rack shaft; a rack housing housing the rack shaft; a motor unit having a motor case of which one end is coupled to the rack housing; a moving force application mechanism that moves the rack shaft by an output of the motor unit; and a support member that is fixed to the rack housing and supports the motor case. The rack housing has a fixing projection in which a bolt hole extending in a height direction is formed. The support member has an arc-shaped support part that extends along an outer circumferential surface of the motor case, and a pair of fixing pieces that protrudes from the support part toward a rack shaft housing section. Ends of the pair of fixing pieces are fastened with a bolt to the fixing projection of the rack housing. |
| US10780911B2 |
Steering column for a motor vehicle and method for producing a steering column
A steering column includes a jacket tube with a clamping section with a slot extending longitudinally. A clamping collar has transversely opposed legs are interconnected via an arcuate section between which the clamping section of the jacket tube is at least partially accommodated. An actuating unit is arranged in the jacket tube, with a steering spindle rotatably mounted therein around the longitudinal axis. A clamp fixes the actuating unit longitudinally relative to the jacket tube and in a release position unclamps the clamping collar and frees the actuating unit longitudinally and presses the legs toward each other transversely to the longitudinal axis in the fixing position. Driver elements are arranged on the jacket tube in opposite edge regions of the slot, and the legs include contact elements which in the fixing position can be pressed against the outer sides of the driver elements. |
| US10780905B2 |
Position determination method and system
A method of determining the geographical position of a rail vehicle travelling on a defined route that has a number of known stopping locations separated by known distances. The method comprises steps of: recording a linear speed signal of the vehicle; processing the linear speed signal to identify a plurality of preceding stationary periods when linear speed equals zero, including a last stationary period, and to calculate the distance traveled between the plurality of preceding stationary periods; comparing the calculated distances with the known distances between stopping locations, to match the last identified stationary period to a corresponding one of the known stopping locations and identify the direction of travel of the rail vehicle; and determining the geographical position of the rail vehicle by processing a portion of the speed signal obtained since the last identified stationary period, to calculate the distance traveled from the corresponding stopping location. |
| US10780899B1 |
Foldable aerodynamic drag reducing plate assembly for a domestic or intermodal container
The embodied invention is a foldable aerodynamic drag reducing plate assembly that is installed on shipping container front ends. The drag reducing plates incorporate hinges and attaching components specifically designed for the spacing and position of vertical rods that are part of a standard shipping container. The drag reducing plates include locking bars that provide stability against air wind when a train moves at high speeds. Also, connecting clips, stiffening channels, or hinges are used to combine the drag reducing plate elements design into a single unit. |
| US10780895B2 |
Throttle control graphical user interface for a work vehicle
A control system for a work vehicle system includes a controller that instructs a graphical user interface to present a first indication having a member extending between a first end positioned below a second end, wherein the second end is positioned above the first end, and present a second indication indicative of an engine speed range, such that the second indication includes a lower engine speed value and an upper engine speed value. In addition, the controller instructs the graphical user interface to selectively present a first symbol at the first end and a second symbol at the second end to indicate that an engine speed varies between the lower engine speed value and the upper engine speed value, and selectively present only the first symbol at the first end to indicate that the upper engine speed value corresponds to a target engine speed. |
| US10780894B2 |
Vehicle control device and vehicle control system
The purpose of the present invention is to provide a vehicle control technique that enables the safety of function substitution to be increased. This vehicle control device determines whether a substitution was successful by monitoring the operations which follow initiation of the substitution. |
| US10780891B2 |
System and method for responding to driver state
A method for controlling vehicle systems includes receiving monitoring information from one or more monitoring systems and determining a plurality of driver states based on the monitoring information from the one or more monitoring systems. The method includes determining a combined driver state based on the plurality of driver states and modifying control of one or more vehicle systems based on the combined driver state. |
| US10780890B2 |
Vehicle systems and methods for detecting and mitigating an incapacitated driver
Vehicle systems and methods for controlling a vehicle to mitigate the effects of an incapacitated driver are disclosed. In one embodiment, a vehicle includes one or more sensors, one or more processors, and one or more non-transitory memory modules communicatively coupled to the one or more processors. The memory modules store machine-readable instructions that, when executed, cause the one or more processors to receive one or more signals output by the one or more sensors and determine a driver of the vehicle is incapacitated based on the one or more signals output by the one or sensors. In response to determining the driver is incapacitated, the processors are caused to determine a specific type of incapacitation of the driver based on the one or more signals output by the one or more sensors. The processors may select an individual vehicle control profile based on the specific type of incapacitation. |
| US10780886B2 |
Hydraulic pressure control device
Provided is a hydraulic pressure control device. A hydraulic pressure control device includes a solenoid valve configured to supply hydraulic pressure to switch between an engaged state and a released state of a lock-up clutch, and a transmission control device configured to control the solenoid valve. The solenoid valve supplies hydraulic pressure to switch between a parking locked state and a parking released state of a parking lock mechanism, in addition to switching of the lock-up clutch. |
| US10780883B2 |
Precipitation detection
An amount and type of precipitation, and a speed of a vehicle is determined. A component in the vehicle is actuated based on the amount and type of precipitation, and the speed of the vehicle. |
| US10780882B2 |
Lane keeping controller
A lane keeping controller includes a first initial target steering angle calculator, a second initial target steering angle calculator, and a steering angle calculator. A first arithmetic unit of the first initial target steering angle calculator performs a first arithmetic operation to calculate a first initial target steering angle using a lane curvature so that a vehicle runs along the lane curvature. A second arithmetic unit of the second initial target steering angle calculator performs a second arithmetic operation to calculate a second initial target steering angle using a yaw angle deviation so that a yaw angle to lane agrees with a target yaw angle. During execution of override control, the lane curvature and the yaw angle deviation are not corrected and a target steering angle is made to be small in comparison with that during execution of normal lane keeping control. |
| US10780880B2 |
Multi-model switching on a collision mitigation system
Systems and methods for controlling an autonomous vehicle are provided. In one example embodiment, a computer-implemented method includes receiving data indicative of an operating mode of the vehicle, wherein the vehicle is configured to operate in a plurality of operating modes. The method includes determining one or more response characteristics of the vehicle based at least in part on the operating mode of the vehicle, each response characteristic indicating how the vehicle responds to a potential collision. The method includes controlling the vehicle based at least in part on the one or more response characteristics. |
| US10780876B2 |
Method and apparatus for storing kinetic energy within an automatic transmission accumulator
A system for a vehicle is disclosed. The system may include an accumulator, a pump, and a controller. The controller may be configured to, responsive to braking of the vehicle, close a line pressure regulator to isolate the accumulator and pump from a transmission pressure line demand, and operate the pump to charge the accumulator without satisfying any of the demand, and responsive to a tip-in event, open the line pressure regulator and operate the accumulator and pump to satisfy the demand. |
| US10780867B2 |
Automatic brake assist device for an electric two-wheeled vehicle
An automatic brake assist device for an electric two-wheeled vehicle, the electric two-wheeled vehicle includes a main control module, having: a radar sensor module, used to measure a distance from a pair of objects; a control module, connected to the radar sensor module and the main control module, when the distance is changed from greater than a first braking distance to less than the first braking distance, transmitting a first brake braking mode signal to the main control module to decelerate the electric two-wheeled vehicle; when the distance is changed from greater than a second braking distance to less than the second braking distance, transmitting a second brake braking mode signal to the main control module to decelerate the electric two-wheeled vehicle; when the distance is changed from greater than a third braking distance to less than the third braking distance, transmitting a third brake braking mode signal to the main control module to decelerate the electric two-wheeled vehicle. |
| US10780866B2 |
Vehicle brake mechanism with pedal-jam detection capability
A vehicle brake mechanism that includes a pedal, a piston attached to the pedal, a spring associated with the piston and exerting a longitudinal force on the piston in a direction opposite the braking direction in order to bring the pedal to a resting position, and an autonomous brake module. A manual braking force on the pedal causes a longitudinal movement of the piston and displaces a transmitter element integrally joined to the piston. The autonomous brake module causes a movement of an intermediate plate that displaces the transmitter element and the piston, exerting a longitudinal force on the piston in the braking direction. The brake mechanism determines the force in the direction opposite the braking direction using a sensor situated on or in the intermediate plate and/or the transmitter element. |
| US10780862B2 |
Vehicle wiper device
The versatility of a water collecting member is raised while improving the ease of assembly of the water collecting member. A water collecting member 80 is formed with plural first marks 90 serving as markers for assembly of the water collecting member 80 to a first pivot holder 20. The first pivot holder 20 is formed with a second mark 92 serving as a guide for the correct assembly orientation of the water collecting member 80 to the first pivot holder 20. The second mark 92 is formed corresponding to one out of the plural first marks 90, and is configured so as to form a pair with that first mark 90. The water collecting member 80 can be assembled in the correct position by aligning the second mark 92 and the first mark 90 that form a pair when assembling the water collecting member 80 to the first pivot holder 20. This thereby enables incorrect assembly of the water collecting member 80 to be prevented when assembling the water collecting member 80 to the first pivot holder 20 in cases in which a universal water collecting member 80 is employed in various vehicle models. |
| US10780861B2 |
Liquid droplet path prediction
A system includes a processor and a memory storing instructions executable by the processor to predict a path of a liquid droplet on a surface, and then, actuate one or more vehicle components based on the path. |
| US10780858B2 |
Airbag device
An airbag device includes an airbag, an inflator and a retainer. The retainer includes a generally tubular holding section for holding the inflator therein and mounting means which protrudes out of the holding section in a direction generally perpendicular to an axis of the inflator to be mounted on a vehicle body member in order to mount the airbag and the inflator on the vehicle body member. The holding section includes an elastically deformable support region which has been elastically deformed and brought into abutment against an outer circumference of the inflator when the inflator was inserted into the holding section, and supports the inflator in the elastically deformed state at an inner side of the holding section, and a supporting projection which has higher rigidity than the elastically deformable support region and abuts against the outer circumference of the inflator at the inner side of the holding section. |
| US10780856B2 |
Real-time vehicle environment recognition and collision identification system
Embodiments of the present invention provide a system for recognizing environment of a vehicle and identifying collisions in real-time. The system is typically configured for continuously monitoring environment of an automobile via one or more components of the automobile, identifying at least one collision associated with the automobile based on monitoring the environment of the automobile, determining one or more users associated with the at least one collision, determining one or more third parties associated with the one or more users and the at least one collision, automatically establish a communication link with the one or more third party entities, and automatically transmitting a notification associated with the at least one collision to the one or more third party entities and the one or more users in real-time. |
| US10780854B1 |
Push bumper integrated with bike rack
A combination push bumper/bike rack for use with police or other emergency vehicles for situations when a disabled vehicle may need pushing, a bike may need to be transported or both. The push bumper is attached to the original bumper of a vehicle and spaced in front of such original bumper to prevent damage to the vehicle when it pushes other vehicles. At the top portion of the push bumper are a pair of retractable arms with straps that can be deployed using a push button. When the retractable arms are not in use they remain flush with the push bumper. When the retractable arms are deployed that are positioned substantially perpendicular to the push bumper and are capable of carrying a bicycle thereon with straps to secure them thereto. |
| US10780853B2 |
External lube system for a transmission
The present disclosure is related to a transmission for a powered vehicle. The transmission includes a housing defining an interior of the transmission and a fluid supply portion disposed in the housing. The fluid supply portion is configured to supply fluid throughout the transmission. The transmission also includes a first fluid circuit disposed within the housing and defining a first fluid path in fluid communication with the fluid supply portion. A second fluid circuit fluidly defines a second fluid path in fluid communication with the fluid supply portion. The transmission further includes a coupling mechanism for fluidly coupling the first fluid circuit and second fluid circuit, wherein the second fluid circuit is disposed outside the housing of the transmission. |
| US10780850B2 |
Aircraft supplemental electrical power systems and methods
Supplemental power systems for aircraft are described. One example is a power conversion system for an electrical power system in a twin engine aircraft having a first generator and a second generator is described. The power conversion system includes a first branch, a second branch, and a selector. The first branch has a first input, a first power converter, and a first output configured for coupling to an aircraft electrical distribution system. The second branch includes a second input, a second power converter, and a second output configured for coupling to the aircraft electrical distribution system. The selector is coupled between the first branch and the second branch. The selector is configured to selectively connect the first generator to the first branch or to the first and second branches. The selector is also configured to selectively connect the second generator to the second branch or the first and second branches. |
| US10780849B1 |
Electric drive units with integrated power electronics for vehicle powertrains
Presented are electric drive unit (EDU) assemblies with integrated power electronics, methods for making/operating such EDU assemblies, and motor vehicles equipped with such EDU assemblies. An EDU assembly includes an outer housing that mounts to a vehicle body. The EDU outer housing has internal motor and transmission chambers and an external cavity. A traction motor is mounted inside the motor chamber and drives one or more vehicle wheels to thereby propel the vehicle. A gear train is mounted inside the transmission chamber and drivingly connects the traction motor to the vehicle wheels. An integrated power electronics (IPE) unit, which is operable to control the traction motor, includes an IPE outer housing with a housing chassis mounted inside the external cavity, and a main housing mounted on the housing chassis to define therebetween a power electronics (PE) chamber. Multiple integrated circuit (IC) PE modules are mounted inside the PE chamber. |
| US10780843B2 |
Methods for forming and tuning the durability of breakaway sections on a trim panel
Doors for motor vehicles include door trim panel assemblies having multiple door trim panels held together at attachment points. A door trim panel includes a weakened perimeter formed from a series of apertures in the panel, creating a predetermined breakaway point where the assembly will rupture in the event a load is applied. Methods for tuning the durability of a trim panel assembly include a repeatable cycle in which pins are selected and inserted in a mold at varying positions. During injection molding, the pins form apertures to create a predetermined breakaway point. Changing the size, shape, and location of the pins allows tuning of the durability and properties of the breakaway point. Injection molds have variable pin placement capability to facilitate the method. |
| US10780841B2 |
Demountable camera module for a vehicle
A vehicle assembly includes, among other things, a camera module that is moveable back and forth between a first and a second position. In the first position, the camera module is mounted to, and at least partially housed within, a portion of a vehicle. In the second position, the camera module is mounted to a structure other than the vehicle. A viewing method includes using a camera module to view a first area when the camera module is at least partially housed within a portion of a vehicle in a first position. The method further includes using the camera module to view a different, second area after moving the camera module to a second position where the camera module is mounted to a structure other than the vehicle. |
| US10780840B1 |
Cellphone stand drawer apparatus
A cellphone stand drawer apparatus for supporting a cellphone in a vehicle includes a housing having a housing interior. A drawer track is coupled to the housing and a pair of drawer sides is coupled to the drawer track. A drawer front and a base are coupled to the pair of drawer sides. An opener arm moves the pair of drawer sides from a closed position to an alternate open position. A touch latch is coupled to the housing and the drawer front. A cradle axle is coupled to the pair of drawer sides and a pair of cradle arms is coupled to the cradle axle. The pair of cradle arms pivots and slides on the cradle axle to secure a cellphone both within the drawer apparatus in the closed position and standing in the open position. |
| US10780835B2 |
Integral foldable hook arrangement
An integral hook arrangement for hanging accessories in a vehicle interior, has at least one hook element and an integral hook base. The integral hook base is designed as a single piece with the or each hook element and is connected pivotably via at least one live hinge such that the or each hook element can pivot from a folded-in stowed position into a folded-out operating position with an opening angle. The integral hook arrangement here has a stop element, wherein a removable abutment and/or engagement is or can be formed between the integral hook base and the or each hook element in order to limit the opening angle in the folded-out operating position. |
| US10780834B2 |
Apparatus for containing debris within vehicle interior door compartments
A removable cover for maintaining debris and other items in an inner door compartment of a vehicle. The removable cover can be removed from the door compartment and when in use prevents debris from blowing out of the door compartment. The removable cover has an opening with flexible flaps for allowing the user to place items in the door compartment during use. The removable cover can be used with a debris wall or dam that prevents debris from moving from a storage area of the door compartment to a drink holder area. |
| US10780826B2 |
Method for determining misalignment of a vehicular camera
A method for determining misalignment of a vehicular camera and calibrating the misaligned camera includes providing a plurality of cameras at a vehicle and providing a control having an electronic control unit that includes a processor for processing image data captured by the plurality of cameras. Frames of image data captured by the plurality of cameras are processed to determine objects present in the field of view of at least one of the cameras. Responsive to processing vehicle data during driving of the vehicle, a vehicle motion vector is determined. Movement of an object relative to the vehicle is determined via processing of at least two frames of captured image data during driving of the vehicle. Responsive to determination of a difference between the relative movement of the object and the vehicle motion vector, misalignment of a misaligned camera is determined, and calibration of the misaligned camera is adjusted. |
| US10780825B1 |
System and a method for alerting a driver of presence of a passenger in a vehicle
A system and a method of alerting a driver of a vehicle of the presence of a passenger in the vehicle are disclosed. The system comprises a control unit in the vehicle to detect the status of an ignition switch in the vehicle. The system further comprises a control device coupled to the control unit. The system further comprises a plurality of wearable devices, each wearable devices is worn by a passenger in the vehicle. The control unit detects turning OFF of the ignition switch and sends a signal to the control device. The control device sends a transmission signal to the wearable devices to determine the presence of any of the wearable devices. The control device generates an alert to the driver when any of the wearable devices respond to the transmission signal indicating presence of the passenger inside the vehicle when the ignition switch is turned OFF. |
| US10780823B2 |
Safety sign device with modular dual signs and related methods
A safety sign device is for a vehicle. The safety sign device includes a first sign having proximal and distal end, a first hinge being coupled to the proximal end of the first sign, the first hinge being coupled to a side of the vehicle, and a second sign being coupled to the side of the vehicle and being substantially parallel to the side of the vehicle. The first hinge is configured to extend and retract the first sign between a retracted position and an extended position. The first and second signs may be transverse to each other in the extended position, and may be flat against the side of the vehicle in the retracted position. The safety sign device includes a first flexible arm coupled to the first hinge and having an elongate housing, and visual indicators carried by the elongate housing. |
| US10780822B1 |
Vehicle exclusion zone monitoring assembly and method
A vehicle assembly includes, among other things, an emitter system of a vehicle, a sensor system of the vehicle, and at least one lighting device of the vehicle. The emitter system is configured to project a marker to provide a visual representation of an exclusion zone adjacent the vehicle. The sensor system is configured to detect a position of an individual relative to the exclusion zone. The vehicle configured to redirect light from the at least one lighting device based on the position of the individual relative to the exclusion zone. |
| US10780820B1 |
Vehicle door pillar light assembly and method of use thereof
A vehicle door pillar light assembly for illuminating a vehicle door and a method of warning drivers of vehicles, having a vehicle door frame defining an opening for entering and exiting a vehicle, a door hingedly connected to the frame and moveable between open and closed positions, and a device for detecting whether the door is open or closed. The assembly further includes a light mounted within the door frame which is electrically connected to the device for detecting whether the door is open or closed. The light is illuminated when the door is opened and unilluminated when the door is closed. When the light source is positioned on the rear of the door frame, it illuminates the vehicle door and objects disposed between the light source and the, when the door is in the open positions, in order to increase the conspicuity of the opened door. |
| US10780818B2 |
Tri-state trailer pigtail
A tri-state electronic vehicle system control circuit comprises a plurality of 3-position switches, each of which is coupled to a dedicated pin on a wiring harness for coupling multiple portions of a combination vehicle such as a tractor-trailer combination. Each switch controls a device (e.g., brake lights, turn signal, etc.) and a data link that can be selectively toggled in a manner that permits data transmission without perceptibly affecting device function. Alternatively, two devices controlled by a given switch can be enabled by a single pin on the wiring harness. The tri-state switching circuitry thus doubles the capacity of the wiring harness to which it is applied. |
| US10780817B2 |
Metal wrapped bungee assembly
A metal wrapped bungee assembly that resists abrasion and corrosion includes a bungee cord that includes an elastic member and a pair of hooks. The bungee cord is stretchable between objects for attaching the objects together. Additionally, the elastic member is comprised of a resiliently stretchable material. A sleeve is positioned around the elastic member of the bungee cord. The sleeve is comprised of a metallic material for protecting the elastic member from abrasion. Moreover, the sleeve comprises a plurality of enmeshed wires such that the sleeve is expandable and collapsible along a longitudinal axis extending through each of the hooks. The sleeve is comprised of a corrosion resistant to resist rusting in the rain. |
| US10780816B2 |
Bunk with adjustable attitude
The present invention relates to a bunk with adjustable attitude for a vehicle cab. The bunk includes a hinge, bunk frame provided with a mattress support surface, a lock insert, and a plurality indexing holes. The bunk frame is pivotably mounted to the hinge about an axis so that at least one of the pitch or roll of the mattress support surface may be selectively adjusted. The lock insert releasably engages the indexing holes to releasably hold the bunk frame at a plurality of selectable pivot angles about the axis. |
| US10780811B1 |
Absorber for cup holder
An absorbing device is configured to fit into standard vehicle cup holders. These configurations may include an absorbing body with a breakable connection disposed in the absorbing body. The breakable connection may circumscribe a removeable area of the absorbing body that is small than the absorbing body in its entirety. In one implementation, the breakable connection permits the area to remove from the absorbing body while leaving the absorbing body intact. |
| US10780807B1 |
Seat mounted adjustable lateral headrest
An adjustable headrest assembly for use with a passenger seat of an aircraft, a seat assembly that includes the headrest assembly, and related methods. The headrest assembly provides lateral support for a passenger's head, and includes a seatback mounted rail, and a headrest that slides along the rail so that the vertical position of the headrest can be adjusted. The headrest assembly also includes a locking mechanism so that the headrest can be releasably locked in a desired vertical position along the rail. |
| US10780803B2 |
Adjustable suspended seat apparatus having tuned frequency-tailored damping through a stratified seat structure
An adjustable suspended seat apparatus having a tuned frequency-tailored damping through stratified seat structure is described. The damping seat structure includes: a first material of a plurality of materials having a first characteristic to provide a first damping effect in a first layer. A second material of the plurality of materials based on a second characteristic to provide a second damping effect in a second layer, the first material or the second material having an adjustable damping characteristic. The suspended seat apparatus includes a seat base configured to have the seat coupled thereto; a suspension system coupled to the seat base, the suspension system comprising: an adjustment feature configured to adjust operation of the suspension system; and a chassis mount coupled to the suspension system, the chassis mount configured to be coupled to a vehicle. |
| US10780799B2 |
Vehicle seat and vehicle
A vehicle seat and a vehicle, with the vehicle seat are provided. The vehicle seat includes a seat cushion, a backrest, and at least one of a cavity located under the seat cushion and a cavity located under the backrest. The at least one cavity includes at least one air intake, at least one air outlet, and at least one drain port. |
| US10780798B2 |
Seat component adjustment actuator, vehicle seat, and method of adjusting a seat component
A seat component adjustment actuator (1) comprises a housing, an electric motor (5), and a gearing (10) coupled to the electric motor (5) and comprising at least three worm transmission stages (11-16). A first worm transmission stage (11, 12) comprises a first worm (11) and a first worm gear (12) engaged with the first worm (11). A third worm transmission stage (15, 16) comprises a third worm (15) and a third worm gear (16) engaged with the third worm (15). The first worm (11) is supported in the housing such that the first worm (11) is rotatable about an input rotation axis. The third worm gear (16) is supported in the housing such that the third worm gear (16) is rotatable about an output rotation axis which is transverse to the input rotation axis. |
| US10780797B2 |
Part fixture
A part fixture which is locked on a locking portion of a vehicle body and which is inserted into a mounting hole on a mount portion provided on a vehicle body to be fixed in place therein to thereby mount the vehicle part on the mount portion, includes an accommodating portion, a locking piece, a pair of flange portions, and a pair of elastic engaging pieces. The elastic engaging pieces each have an engaging claw and an operation knob. When the pair of elastic engaging pieces are deflected inwards of the accommodating portion, the pair of elastic engaging pieces are brought into abutment with the side wall portions or the locking portion of the vehicle part which is accommodated in the accommodating portion so that any further deflection thereof is restricted. |
| US10780791B2 |
Power source system for vehicle
A power source system may include a main power source, a power converter including a capacitor, a relay configured to switch between connection and disconnection between the power converter and the main power source, an auxiliary power source, a boost converter having a low voltage terminal thereof connected to the auxiliary power source, and having a high voltage terminal thereof connected to the power converter without interposing the relay, and a controller configured to pre-charge the capacitor prior to placing the relay in a connected state. During the pre-charging of the capacitor, the controller may be configured to set an output current of the boost converter to a first current value while a specific auxiliary device connected to the auxiliary power source executes a specific process, and change the output current to a second current value larger than the first current value after the execution is completed. |
| US10780790B1 |
Electrical charging system for a vehicle
The electric charging system for a vehicle is configured for use with an electric vehicle. The electric vehicle further comprises one or more electric drive motors. The electric charging system for a vehicle provides electrical energy to the one or more electric drive motors. The electric charging system for a vehicle comprises a plurality of battery banks, a regenerative circuit, and a control circuit. Each of the plurality of battery banks is a chemical device that converts chemical potential energy into electrical energy used to power the one or more electric drive motors of the electric vehicle. The regenerative circuit is a circuit that converts the motion of the electric vehicle into electricity used to recharge the plurality of battery banks. The control circuit regulates and controls the operation of the electric charging system for a vehicle. |
| US10780788B2 |
High voltage component assembly and power supply system for vehicle
The high voltage component assembly includes a first high voltage component and a second high voltage component for operating respectively upon reception of high voltage supply from a supply source, a case body for containing the first high voltage component therein, a lid to be attached to the case body to prevent access to an inside of the case body in a state of the lid being attached to the case body, a fastening member to be fastened in a fastening state to fix the lid so as not to be detached from the case body, a receptacle to which the second high voltage component is attached, the receptacle being provided at a position precluding release of the fastening member from the fastening state in a state of the receptacle receiving the second high voltage component attached, and a cutoff device for cutting off the supply of the high voltage from the supply source upon detachment of the second high voltage component from the receptacle. |
| US10780787B2 |
Fuel cell vehicle and control method thereof
A control method of a fuel cell vehicle comprises estimating a load applied to an own vehicle that is the fuel cell vehicle and that runs on an estimated route by using current traffic flow information or the like in addition to the estimated route; determining whether an overload area is present on the estimated route by using the estimated load; and when it is determined that the overload area is present on the estimated route, performing an increasing process of increasing a cooling power of a cooling system to be greater than a cooling power set in an ordinary control mode before the own vehicle reaches the overload area. |
| US10780776B2 |
Vehicle underbody
A vehicle understructure includes a hydrogen tank that is disposed along a longitudinal axis of a vehicle. At least an upper portion of the hydrogen tank is enclosed in a floor tunnel. The hydrogen tank includes dome portions that are disposed at both ends of a cylindrical center body portion of the tank, and at least one valve portion that protrudes from at least one of the dome portions. The vehicle understructure also includes a brace that extends along a transverse axis of the vehicle and is secured to transversely outer side portions of the floor tunnel. The brace is at least partially overlapped with at least one of the dome portions when viewed from the front or rear of the vehicle. |
| US10780771B2 |
Drive device for hybrid vehicle
A drive device for a hybrid vehicle includes an engine, a first motor, a power split device, a second motor, a first speed reduction unit, a second speed reduction unit, and a differential gear. The first motor generates electric power. The power split device splits drive power output from the engine to the first motor side and a drive wheel side. The second motor increases or decreases torque output from the power split device and to be transmitted to the differential gear. The second motor is coupled to a sun gear. The first speed reduction unit is coupled to the sun gear. The second speed reduction unit is provided between the first speed reduction unit and the differential gear. The differential gear transmits torque to the drive wheel. |
| US10780769B1 |
Power transmission apparatus of hybrid electric vehicle
A power transmission apparatus of a hybrid electric vehicle using an engine and first and second motor/generators as power sources, may include a first shaft, a second shaft which is selectively connectable to the first shaft and fixedly connected to the first motor/generator, a third shaft selectively connectable to the first shaft, a fourth shaft coaxially mounted with the third shaft, a fifth shaft transferring rotational power transmitted from the third and fourth shafts to a final reduction gear, a sixth shaft fixedly connected to the second motor/generator, a seventh shaft transferring rotational power transmitted from the sixth shaft to the final reduction gear and a planetary gear set including first, second, and third rotation elements wherein the first to seventh shafts are externally gear-meshed with each other by four gear sets so that rotational power is transmitted. |
| US10780761B2 |
Inside-outside air switching unit
An inside-outside air switching unit includes a switching member in an inside-outside air case and a drive unit that is configured to operate the switching member. The switching member is configured to open and close an outside-air inlet and an inside-air inlet. The switching member includes a first switching door and the second switching door. The first switching door is configured to be positioned by the drive unit to open the outside-air inlet in the inside-outside air intake mode. The second switching door is configured to be positioned by the drive unit to open the inside-air inlet in the inside-outside air intake mode. The drive unit is configured to move the first switching door to close an inside-outside communication passage, which is defined in the inside-outside case between the outside-air inlet and the inside-air inlet, in the inside-outside air intake mode. |
| US10780755B2 |
Oscillating arm of a motor-vehicle suspension
It is herein described an oscillating arm for a motor-vehicle suspension having a first rod element and a second rod element. The second rod element is a half-shell rod that provides a cavity. The oscillating arm also comprises at least one insert, made of plastic or fiber-reinforced composite material, which fills the cavity of the half-shell rod. |
| US10780754B2 |
Spring suspension
A spring suspension includes a support assembly, two shock absorbing columns, two shock absorbing springs, two suspension rocker arms, two connectors and two connecting rods. The two shock absorbing columns are arranged on the support assembly symmetrically. The two suspension rocker arms are arranged on two ends of the support assembly in an opposing manner. Each shock absorbing spring sleeves the corresponding shock absorbing column which is also movably connected to the corresponding connector. Each of the connectors and the corresponding connecting rod are coaxially arranged on a cart body, and an articulation point between the connector and the connecting rod is located between the two shock absorbing columns. Each of the connecting rods is movably connected to the corresponding suspension rocker arm. The spring suspension of the utility model has a simple structure and is capable of improving the off-road performance of a golf cart. |
| US10780753B2 |
Trailer hitch
In order for a trailer hitch, comprising a pivot bearing unit mountable on a rear end portion of a vehicle body, in fixed relation to the vehicle, and a pivot element supported on the pivot bearing unit for pivotal movement about at least one pivot axis, said pivot element having fixedly connected thereto a ball neck carrying a hitch ball, said ball neck being pivotable, by pivoting the pivot element about the at least one pivot axis relative to the pivot bearing unit, between two final positions, one of which is an operating position and another one of which is a rest position, to be improved such that the location of the pivot element can be detected as simply and unambiguously as possible, it is proposed that a sensor system be provided for detecting at least one location of the pivot element relative to the pivot bearing unit with respect to the at least one pivot axis, which sensor system detects the locations of the pivot element relative to the pivot bearing unit mounted in fixed relation to the vehicle and generates position information representative of the respective location of the pivot element. |
| US10780746B2 |
Pneumatic tire
A pneumatic tire is provided that can achieve performance that is equivalent to or higher than that of known tires while allowing weight reduction of bead cores by using, for the bead cores, a composite cord. A pneumatic tire includes annular bead cores (5) embedded in bead portions (3), and a carcass layer (4) locked on the bead cores (5). Each of the bead cores (5) includes a cable bead structure in which a composite cord (10) is spirally wound around an annular core body (20), the composite cord including a core wire (11) formed of carbon fibers and a plurality of siding wires (12) formed of glass fibers disposed around the core wire (11). |
| US10780742B2 |
Tire
In a tire, a tread rubber includes a first layer which is grounded on a road surface in an outer peripheral surface thereof, and a second layer which is joined to an inner peripheral surface of the first layer in an outer peripheral surface thereof, the first layer includes a joint portion where rubbers having different elastic modulus are joined, and the second layer is formed by a rubber having a greater elastic modulus than an elastic modulus of at least one of the rubbers constructing the first layer. |
| US10780736B2 |
Dropout assembly
A dropout assembly comprises a first dropout that includes a first through hole configured to receive an axle for a bicycle wheel. The dropout assembly also comprises a second dropout that includes a second through hole and a mounting surface. The second through hole is configured to receive the axle for the bicycle wheel. The dropout assembly also includes a rotational control mechanism that is configured to mount to the mounting surface of the second dropout. The rotational control mechanism includes a nut and a nut cover. |
| US10780735B2 |
Hub unit
A hub unit that is to be installed on a vehicle is provided with: an outer ring having, on the inner circumferential surface, a first outer raceway surface and a second outer raceway surface that is disposed to the outside of the first outer raceway surface in the vehicle width direction when the hub unit is installed on the vehicle; an inner shaft that is disposed on the inside of the outer ring concentrically with the outer ring and on which a wheel is installed on the outer end in the vehicle width direction; and an inner ring that is press-fitted to the inner shaft on the inner end in the vehicle width direction. |
| US10780734B2 |
Tire sidewall shading device and attachment system
A shading system for tires and wheels being built to a customized shape and size to cover at minimum the sidewall of a tire. The shading system may be comprised of, but is not limited to, multiple layers of shading material offering ultraviolet and heat protection for the covered area and a multipoint harness to secure the shade to the tire. |
| US10780730B2 |
Handheld implement in particular writing instrument
A handheld implement having a shaft with two shaft parts which are releasably connectable together via a plug-in coupling, with a coupling unit at each front end of the shaft parts. Each coupling unit has a slide held in a guide hole open on a face side in the associated shaft part and protrudes beyond the guide hole with a slide portion, the free end of which is formed as a latching fork that has a latching opening. The slide portion bears a latching protrusion behind the latching fork in the sliding direction. The coupling unit has a guide sleeve that encloses the slide and is guided into the guide hole counter to a restoring force, and when the front ends, having the coupling units, of the shaft parts are pressed together, the latching fork of one coupling unit is latchable on the latching protrusion of the other coupling unit. |
| US10780729B2 |
Information recording medium and individual certificate medium
An individual certificate medium includes an optical security patch in which a relief layer and a metal layer include a first area and a second area. The first area includes an altered region and a portion of the relief layer overlapping with the altered region as viewed in the thickness direction of a recording layer. The second area includes a non-altered region and another portion of the relief layer overlapping with the non-altered region as viewed in the thickness direction. As viewed in the thickness direction, the first area transmits light incident thereon, while the second area absorbs light incident thereon to hide a recording region. In a direction intersecting the thickness direction, the first and second areas cause light incident on the optical security patch to emerge as diffracted light. |
| US10780726B2 |
Micro-optic device with double sided optical effect
A micro-optic device, including: a transparent substrate; first lens elements on a first side of the substrate that reveal first image elements on a second side of the substrate; and second lens elements on the second side of the substrate that reveal second image elements on the first side of the substrate. |
| US10780718B2 |
Liquid discharge apparatus and liquid discharge method
A liquid discharge apparatus includes a liquid discharge device, circuitry, and a curing device. The liquid discharge device is configured to discharge a liquid having a curing degree variable by a stimulation amount while relatively moving to a recording medium. The circuitry is configured to acquire surface roughness information indicating glossiness of a formed object formed on the recording medium and set a stimulation amount for the liquid based on the surface roughness information. The curing device is configured to stimulate the liquid discharged by the liquid discharge device based on the stimulation amount set by the circuitry to cure the liquid. The circuitry is configured to set, based on the surface roughness information, the stimulation amount for each region stimulated by the curing device in a same plane of the formed object. |
| US10780716B1 |
System and device for attenuating curl in substrates printed by inkjet printers
An aqueous ink printer includes a moisture applicator that applies moisture to a side of a substrate that is opposite a side that bears or will bear an ink image. The moisture applicator includes a switching network that is configured to independently and selectively bias the tile segments electrically. The tile segments contiguously cover a surface of the roller. As the switching network is operated to electrically bias the tile segments using data corresponding to the ink image, they transition from being hydrophobic to hydrophilic so the electrically-biased hydrophilic tile segments attract moisture from water in a trough or from water vapor produced by an ultrasonic transducer in the trough. The moisture is carried by the electrically-biased tile segments to the substrate at areas where the amount of ink in a portion of the substrate on the other side of the substrate exceeds a predetermined ink coverage threshold. |
| US10780712B2 |
Drawing apparatus, method of drawing, and recording medium
A drawing apparatus includes a drawing head drawing a pattern on the surface of a target nail of a hand or foot; and a processor. The processor controls the drawing head to scan a plurality of times across an area on the surface of the nail and to draw the pattern on the area during each of the plurality of scanning operations of the drawing head based on a curvature of the nail. |
| US10780711B2 |
Drawing apparatus, method of drawing, and recording medium
A drawing apparatus includes a processor determining the aspect ratio of the surface area of a target nail of a finger or a toe, and entering a first fitting mode to modify the aspect ratio of at least one nail design in accordance with the surface area of the target nail and to fit the at least one nail design to the surface area of the nail. The rate of modification of the aspect ratio of the at least one nail design is within a modification threshold of the at least one nail design. |
| US10780710B2 |
Recording method and recording device
Recording method including emitting laser light from optical fiber array to record image formed of writing units with moving recording target and the optical fiber array relatively using recording device including laser light-emitting elements and emitting unit including the optical fiber array where optical fibers configured to guide laser light emitted from the laser light-emitting elements are aligned, wherein the image includes convex-concave shapes formed by aligning convex portions relative to, as standard, vertical line to the writing units where the vertical line includes the nearest contact points at endmost side of the image in sub-scanning direction where the image is formed by overlapping or adjoining at least part of the writing units in main-scanning direction and satisfies formula below: T≤0.4X where T is average height of the convex portions and X is minimum distance between centers of the adjacent writing units in the image. |
| US10780703B2 |
Channel control apparatus and inkjet recording apparatus
A channel control apparatus includes: a diaphragm portion displaceable between an opening position to open a channel and a closing position to close the channel; an abutment portion for moving in a first direction and a second direction opposite to the first direction by a driving source; and a gripping member that has an inclined surface portion for abutting against the abutment portion and grips the diaphragm portion, wherein when the abutment portion moves in the first direction, the gripping member displaces the diaphragm portion to the opening position by the abutment portion abutting against the inclined surface portion, and wherein when the abutment portion moves in the second direction, the gripping member displaces the diaphragm portion to the closing position by the abutment portion being separated from the inclined surface portion. |
| US10780701B2 |
Liquid ejecting apparatus
A printer includes a head including an ink ejecting unit for ejecting ink from a nozzle, a waste liquid flow path that is a flow path of ink sucked from the nozzle, a suction unit that performs an ink suction operation of sucking the ink from the nozzle via the waste liquid flow path, and a cleaning operation of sucking cleaning liquid from the nozzle via the waste liquid flow path, and a control unit that controls the suction unit so as to vary a suction amount of the cleaning liquid depending on an elapsed time from when the ink suction operation is performed, when the cleaning operation is performed. |
| US10780698B2 |
Inverted TIJ
A fluid ejection die includes a substrate including an array of nozzles. |
| US10780696B2 |
Printbars and methods of forming printbars
A method of forming a printbar module may include providing a printed circuit board (PCB) having a recess extending partially through the PCB and a dam surrounding the recess. An adhesive material may be applied to the recess and a printhead die sliver may be positioned in the recess. The printhead die sliver may be bonded with the PCB and the printhead die sliver and the PCB may be encapsulated with a molding compound. In response to encapsulating, a slot, extending through the PCB and the adhesive material may be formed, wherein the slot is in fluidic communication with fluid feed holes of the printhead die sliver to provide direct fluidic communication without fan-out. |
| US10780684B2 |
Bonding device
A bonding device includes a flexible platen disposed between an upper platen assembly (9) and a transmission device and within a vacuum chamber (6). The flexible platen can expand to apply a downward pressure to the upper platen assembly (9) connected thereto. Under the effect of the pressure, the upper platen assembly (9) slowly moves downward until the upper platen assembly (9) itself and a lower platen assembly (7) respectively come into tight contact with objects to be bonded. After that, the flexible platen continues exerting the downward pressure on the upper platen assembly (9). In this way, the pressure applied by the upper platen assembly (9) to the objects to be bonded is uniform. Meanwhile, because of slow expansion of the flexible platen, the uniform pressure is applied slowly by the upper platen assembly (9). |
| US10780671B2 |
Filament wound composite tools and related methods
Composite products and related methods are disclosed. In some examples, methods of filament winding composite components and products, such as a sleeve and/or a mandrel for use in down-hole applications, are disclosed. The winding of components can involve using a percentage of fiber roving strands that are blown during manufacture such that they have fiber loops that when wound as layers forms bridges across the discrete layers to enhance the inter-laminar strength of the composite product. |
| US10780670B2 |
Laminate
The present invention pertains to a carbon fiber reinforced plastic, and provides a carbon fiber reinforced plastic laminated body that is low cost and superior in moldability, mechanical characteristic balance, and impact resistance. The laminated body has three or more layers, and has the following (B) layer between two layers of a fiber reinforced resin sheet, (B) layer: A resin sheet in which the displacement, in an S-S curve waveform obtained by the following high-speed punching test, from a peak value of the test force (kN) to an 85%—attenuation value is not less than 22 mm. High-speed punching test: Impact absorption energy is calculated by using an impact testing machine in compliance with ISO6603-2 standard. A 100 mm×100 mm test piece is cut out from a sheet having a thickness of 2 mm. The diameter of a striker is 12 mm. the diameter of an opening section of a holding tool is 76 mm, and the impact speed is set to 5 m/sec. |
| US10780669B2 |
Films and bags with visually distinct regions and methods of making the same
One or more implementations of a multi-layer film include a first layer non-continuously bonded to a second pigmented layer. The multi-layer film includes an unexpected appearance differing from the appearance of the pigmented layer. In one or more embodiments, the multi-layer film includes a metallic appearance despite the pigmented layer being devoid of metallic pigment. The multi-layer film also includes areas that are visually distinct from areas of the film with the unexpected appearance. The visually-distinct areas comprise areas in which the first layer non-continuously is in intimate contact with the second pigmented layer. The visually-distinct areas have the appearance of the pigmented layer or another appearance. One or more implementations also include methods of making multi-layer films and bags with an unexpected appearance and visually-distinct areas. |
| US10780668B2 |
Surface protection film and related methods
The provided surface protection films include a plurality of layers in the following order: a first polymeric film that is exposed at a major surface of the surface protection film; a foamed adhesive; a second polymeric film; and a pressure-sensitive adhesive. The surface protective films withstand impacts and harsh outdoor conditions, and can be easily applied and removed while minimizing or eliminating the need to use personal protective equipment and volatile organic compounds. |
| US10780663B2 |
Rosin presses and related methodologies
The following pertains to a horizontally-situated high capacity rosin press capable of applying heat and pressure in a chamber to extract and collect rosin from inserted plant materials. The extracted rosin is capable of being collected via gravity-induced drainage, eliminating the need for manual separation of rosin and remaining plant materials. |
| US10780662B2 |
Automatic tire sipe machine
An automatic tire sipe forming machine for forming sipes of uniform depths and at uniform intervals across the circumferential surface of a tire. The automatic tire sipe forming machine includes means for indexing a tire a fixed rotational interval and a reciprocating mechanism for forming the sipes. The automatic tire sipe forming machine further includes means for changing the angle of the sipes and for accommodating various widths and sizes of tires. |
| US10780659B2 |
Patch pod cartridge for a tire repair tool, a tire repair tool including the cartridge and a method of use
A tire repair tool includes a body portion and a cartridge portion. The tool is used to inject an adhesive or glue and a patch into a puncture in a tire, while the tire is still engaged with the wheel, in order to permanently patch a punctured inner tube of the tire. More particularly, a push rod is used to rupture an adhesive pod, elevate an elevator assembly and eject the adhesive and patch through an outlet tube of the tool and into the existing puncture of the outer tire. A patch is affixed over a puncture in the inner tube by the adhesive to permanently patch the inner tube without having to remove the tire from the wheel or rim. |
| US10780657B2 |
Method of filling voids in a filled seal cap
Methods of using and repairing seal caps as well as constructions comprising seal caps, including in some embodiments seal caps which may be useful in sealing fasteners that protrude into fuel storage cells in aircraft. In some embodiments, methods include the use of optically translucent seal cap and application of a second quantity of sealant to fill voids observed within the interior of the seal cap after cure of a first quantity of sealant. |
| US10780654B2 |
Imprinted 3D printed structure, printing method, 3D item and lighting system therewith
The invention provides a method for 3D printing a 3D item (1), the method comprising depositing during a printing stage 3D printable material (201), to provide the 3D item (1) comprising 3D printed material (202), wherein the printing stage comprises: —3D printing a first 3D printable material (201a) to provide a first 3D printed material (202a), the first 3D printable material (201a) comprising a cross-linkable material; —creating a relief structure (610) in the first 3D printed material (202a) with a tool (630); and —3D printing a second 3D printable material (201b) to provide a second 3D printed material (202b), to provide a stack (620) of (i) 3D printed material (202) comprising the first 3D printed material comprising the relief structure (610), and (ii) the second 3D printed material (202b), wherein the method further comprises: —cross-linking at least part of the first 3D printed material (202a) comprising the relief structure (610) before depositing the second 3D printable material (202b). |
| US10780653B2 |
Slicing and printing method for colour 3D physical model with protective film
A slicing and printing method for colour 3D physical model with protective film is provided. The method executes a slicing process to colour 3D object data for generating multiple layers of object slice data and colour slice data, generate multiple layers of body slice data and multiple layers of protection slice data according to multiple layers of the object slice data, manufacture multiple layers of body slice physical models according to multiple layers of the body slice data, color each layer of the manufactured body slice physical model according to the same layer of the colour slice data, and use light-transmissive print materials to manufacture multiple layers of protection slice physical models according to multiple layers of the protection slice data. The method can effectively make the manufactured colour 3D physical model be with light-transmissive protective film, and prevent the colour 3D physical model from decolorization. |
| US10780651B2 |
Application device
An application unit (13) comprises a rotation unit (26) and a support unit (27). The rotation unit (26) comprises a nozzle unit (28), a nozzle support part (29), a body base (30), a first supply part (31), a second supply part (32), a third supply part (33), a valve (34), and a motor (35). The nozzle support part (29) rotatably supports the nozzle unit (28) such that the central axis of the nozzle unit (28) is inclined with respect to the rotation axis of the rotation unit (26). |
| US10780650B2 |
Quick-mount interchangeable sealer and punch for plastic film
A hole cutter/punch arrangement that can be changed over quickly to a different hole cutter or punch or slitter, or can instead be converted to a sealer in manufacture of items from plastic film. A reciprocating drive such as an air cylinder is coupled to a transverse mount or holder, of a T-shaped profile and the punches and sealers each have a mounting shoe with a transverse T-profile channel to slide onto the mount where a detent holds the shoe releasably in place. A triple-tree arrangement of a center drive post and left and right guide posts connects to the transverse holder. |
| US10780648B1 |
Automated balloon assembly machine
An assembly for manufacturing a balloon envelope includes a table component and a sealing component. The table component may include a first platform, a second platform, a third platform, and a lateral opening between the first and second platforms. The first and second platforms can receive a first sheet of material that forms a first gore of the balloon envelope and a second sheet of material that forms a second gore of the balloon envelope. At least a portion of the first platform may move relative to the third platform so as to allow for the tendon and the portion of the second sheet attached to the tendon to move toward the third platform. The sealing component may be configured to bond the first sheet to the second sheet in order to join the first and the second gores of the balloon envelope. |
| US10780647B2 |
Broadband microwave processing system
A microwave processing system includes: a broadband variable frequency microwave (VFM) source; a plurality of waveguide applicators, each of which includes a waveguide transition and is capable of supporting a selected subset of frequencies within the bandwidth of the broadband VFM source; a microwave switching means allowing the microwave source to be connected to any one of the waveguide transitions so that microwave power is delivered to the corresponding waveguide applicator; and wherein each of the waveguide applicators includes at least one channel through which a microwave transparent tube may be run so that process fluid flowing through the tube may be exposed to microwave power in the applicator. |
| US10780646B2 |
Friction pad for a portable electronic device
A friction pad (12) for inhibiting movement of a device (10), e.g., a portable electronic device, relative to an engagement surface (16) includes a pad body (18) having a first body surface (20) and an opposed second body surface (22). The first body surface (20) is configured to be coupled to an outer surface (14) of the portable electronic device (10), and the second body surface (22) is configured to engage the engagement surface (16). The pad body (18) is formed at least in part from a body material (18A) including high-density polyethylene. Additionally, the second body surface (22) of the pad body (18) has a static coefficient of friction of at least approximately 0.60. |
| US10780643B2 |
Stereolithography printer mapping a plurality of pixels of a cross-sectional image to corresponding mirrors of a plurality of mirrors of a digital micromirror unit
Techniques and systems for 3D printing using mirrors that are oriented at about 45 degrees from an X-axis and Y-axis are described. A technique includes receiving an object model; rotating the object model about 45 degrees around the Z-axis; generating cross-sectional images of the rotated object model; mapping pixels of the cross-sectional images to corresponding mirrors of a digital micromirror device of an additive manufacturing apparatus to form additive-manufacturing images, wherein edges of the mirrors are oriented about 45 degrees from the X-axis of the digital micromirror device and about 45 degrees from the Y-axis of the digital micromirror; and providing the additive manufacturing images to generate a build piece corresponding to the object model. Other implementations can include corresponding systems, apparatus, and computer program products. |
| US10780636B2 |
Recoating unit, recoating method, device and method for additive manufacturing of a three-dimensional object
A recoating unit (40) serves for equipping or retrofitting a device (1) for additive manufacturing of a three-dimensional object (2) by selectively solidifying a building material (15), preferably a powder, layer by layer. The device (1) comprises a recoater (16) movable across a build area (8) for applying a layer (31b, 32b) of the building material (15) within the build area (8) and a solidification device (20) for selectively solidifying the applied layer (31b, 32b) at positions corresponding to a cross-section of the object (2) to be manufactured. The device (1) is formed and/or controlled to repeat the steps of applying and selectively solidifying until the object (2) is completed. The recoating unit (40) comprises at least two recoating rollers (41, 42) spaced apart from each other in a first direction (B1) and extending into a second direction transversely, preferably perpendicularly, to the first direction, and a compacting and/or smoothing element (45) arranged between the two recoating rollers (41, 42) in the first direction (B1) and extending into the second direction. The recoating unit (40) is adapted to draw-out building material to a regular layer (31a, 32a), depending on the movement of the recoating unit into the first direction (B1) or into its reverse direction (B2), using the recoating roller (41, 42) arranged ahead in the respective moving direction (B1, B2), and to compact or smoothen the layer (31a, 32a) drawn-out by the recoating roller (41, 42) arranged ahead using the compacting and/or smoothing element (45). |
| US10780635B1 |
Apparatus and method for thermal compensation during additive manufacturing
An additive manufacturing apparatus includes an extruder and a gear pump in fluid communication with extruder. The additive manufacturing apparatus also includes a nozzle in fluid communication with the gear pump. The extruder is connected to a guide member such that at least a portion of the extruder is configured to expand and move along the guide member according to a thermal expansion of the extruder. |
| US10780634B2 |
Nozzle, processing apparatus, and additive manufacturing apparatus
A nozzle according to one embodiment includes a nozzle unit and a guide surface. A first passage, a second passage, and the guide surface are provided to the nozzle unit. The first passage has a first open end. The second passage has a second open end, and a section that is positioned upstream of the second open end and that extends in a second direction. The guide surface has an edge in a first direction. The guide surface is exposed on the outer side at the edge, is along a third direction at the edge, the third direction being a direction becoming more distanced from an axis than the second direction does, as the third direction is extended further toward the first direction. A flow of fluid ejected from the second open end follows the guide surface, and becomes separated from the nozzle unit at the edge. |
| US10780628B2 |
Apparatus and method for fabricating three-dimensional objects
An apparatus for making three-dimensional objects comprises a movable dispensing head to dispense in a fluid state a supply of flexible strand of thermoplastic resin material. Two motors are provided for moving said dispensing head relative to a base member in an x, y plane in a predetermined sequence and pattern. A heater heats flexible strand to a predetermined temperature above the solidification temperature of said material. |
| US10780626B2 |
Method for manufacturing a three-dimensional product
A method is described for manufacturing a three-dimensional product, in particular a hydraulic element, the method encompassing at least the following method steps: Providing a first section of the product to be manufactured, which includes at least one first connection point for a second section of the product to be manufactured; and producing the second section by an additive manufacture in which the at least one first connection point of the first section is used as a substrate for the additive manufacture of the second section. |
| US10780625B2 |
Inverted cylinder assembly for forming and filling a container with liquid
A liquid forming and filling system for filling a container with a liquid. The liquid forming and filling system having a motor, a gear box operably coupled to the motor configured to receive a driving output from the motor and outputting a gear box driving force, a linear screw operably coupled to the gear box configured to produce linear movement in response to rotational movement from the gear box, a forming cylinder configured to output pressurized liquid for forming and filling the container, the forming cylinder being in an inverted orientation, a top manifold plate and end cap vent valve assembly coupled to the forming cylinder for receiving the pressurize liquid, and a vent valve operably coupled to the top manifold plate and end cap vent valve assembly configured to vent air entrapped within the pressurized liquid. |
| US10780617B2 |
Adaptor plate and injection molding machine having such an adaptor plate
The present invention concerns an adaptor plate for connecting a cover plate to a plurality of piston housings of an injection molding machine, wherein the adaptor plate has a first fluid passage and a second fluid passage for feeding a first and a second control fluid into the piston housings, wherein the first fluid passage has at least one first fluid passage inlet for receiving the first control fluid and a plurality of first fluid passage outlets for discharge of the first control fluid to the piston housings and the second fluid passage has at least one second fluid passage inlet for receiving the second control fluid and a plurality of second fluid passage outlets for discharge of the second control fluid to the piston housings. |
| US10780615B2 |
Punch for compression molds
A punch for the compression molding of plastic material for forming capsules for containers closure, wherein the punch includes a stem portion made of steel and a head portion made of copper alloy screwed to the stem portion, wherein a separation interface between the stem portion and head portion includes a passage for gas that reaches a bottom surface of the punch delimitating one forming cavity where the compression molding of the plastic material occurs, and wherein one channel internal to the head portion communicates with the passage for gas to enable extraction of gas out of the forming cavity. |
| US10780611B2 |
Method for co-curing perpendicular stiffeners
A method for fabricating a composite structure is provided. A first number of layers of composite material is laid up to form a first set of stiffeners. A second number of layers of composite material is laid up to form a panel. The first set of stiffeners is associated with a first side of the panel. A pre-cured composite strip is positioned on a second side of the panel, opposite the first side. A third number of layers of composite material is laid up on the second side of the panel to form a second set of stiffeners running perpendicular to the first set of stiffeners. The pre-cured composite lies at an intersection between one of the first set of stiffeners and one of the second set of stiffeners. All the layers of composite material are co-cured to form the composite structure. |
| US10780607B2 |
Plasticizing unit supplying a prescribed amount of fiber material pieces to heating cylinder using a vacuum or blower fiber transfer device
In order to be capable of reliably supplying a prescribed amount of fiber materials into a heating cylinder for each cycle and continuously manufacturing a homogeneous composite material, a plasticizing unit is provided with a fiber supply device 3 that supplies prescribed amount of fiber materials A2 having a prescribed length into the heating cylinder 1. The fiber supply device 3 is provided with: a cutting section 12 that cuts off a long fiber material A1 pulled out from a reel 11 into a prescribed length; a pressure-feeding section 13 that presses the fiber materials A2 having the prescribed length cut off by the cutting section 12 into the heating cylinder 1; and a fiber transfer device 45 that forcibly transfers the fiber materials A2 accumulated in the cutting section 12 to the pressure-feeding section 13. The pressure-feeding section 13 is constituted by a press cylinder 41 and a press piston 42, and the fiber transfer device 45 is constituted by a vacuum device. |
| US10780606B2 |
Nanotube particle device and method for using the same
A nanotube particle device for two dimensional and three dimensional printing or additive/subtractive manufacturing. The nanotube particle device comprising a nanotube, a particle shooter, a positioning mechanism, and a detection sensor. The particle shooter shoots a particle down the nanotube towards a target, the detection sensor senses the collision of the particle with the target, and the positioning mechanism re-adjusts the positioning of the nanotube based on the results of the collision. A method for aiming the particle shooter and additive/subtractive manufacturing are also disclosed and described. |
| US10780604B1 |
Automated multi-headed saw for lumber and associated method
A system including a gantry structure; a first and a second saw head movable along at least part of the length of the gantry structure; and a first and a second lumber support also movable along corresponding lengths of the gantry structure. A controller moves the first saw head and first lumber support adjacent a first location along a board and moves the second saw head and second lumber support adjacent a second location along a board, and operates the first and second saw heads to cut first and second ends off the board. The controller then moves the saw heads and the lumber supports relative to the board to third and fourth locations and operates the first and second saw heads to cut third and fourth end pieces off. The saw heads and lumber supports optionally move together and rotate around respective vertical axes to enable angled board cuts. |
| US10780603B2 |
Interleaver system for high speed slicing machine having brake for web supply
A sheet interleaver is provided for a slicing machine that includes a slicing plane for slicing an elongated food product and a sheet of web material beneath the elongated product. The interleaver includes a supply of web material, a drawing station, and a feed station. A tensioning station is disposed between the supply of web material and the drawing station to maintain the tension of the web material at a pre-determined tension. A web accumulation station is between the drawing station and the feed station to provide a slackened length of web material within an acceptable range of slack between the drawing station and the feed station. The supply of web material is disposed on a spool which rotates about a cylindrical shaft. The cylindrical shaft has a braking mechanism which protrudes from the shaft to generate a frictional force against the spool. |
| US10780599B2 |
Polymeric cutting edge structures and method of manufacturing polymeric cutting edge structures
A functional polymeric cutting edge structure and methods for the manufacturing of cutting edge structures comprised of polymeric materials are provided. The cutting edge structures may be produced on a substrate having a blade body or blade support type. The polymeric material is produced by curing a precursor material activated by electromagnetic radiation wherein a wavelength of said radiation is about double a wavelength required to activate the precursor material. A razor blade for use in a razor cartridge or a blade box may be formed using the present invention. |
| US10780596B2 |
Spacer for razor blade for creating and maintaining a stubble shave appearance
A razor blade assembly that is capable of creating a stubble-like appearance via a manual, low-cost razor. The assembly includes a spacer that maintains a gap or clearance between a blade edge and a surface to be shaved. This gap or clearance facilitates an effect of a shadow- or stubble-like appearance upon the surface. |
| US10780594B1 |
Staggered multilayer trimming head applied in an electric haircutter
A staggered multilayer trimming head installed at a front end of an electric haircutter includes a bottom plate, a fixed blade, a moving knife module and a moving swing block. The moving knife module has a first moving knife and at least one second moving knife; an adjusting lever is coupled to the second moving knife for adjusting the position of the second moving knife with respect to the first moving knife quickly, and the moving knife module is coupled to a motor of the electric haircutter with power connection through the moving swing block. In a cutting/shearing operation, the adjustable moving blade allows the cutting and shearing to be adjusted to a single cutting and shearing track or a multiple of tracks, so as to complete various haircutting effects quickly without changing the operator's original operating habit and improve the haircutting efficiency and quality significantly. |
| US10780591B2 |
Soft robotic actuators and grippers
A method of making an actuator having a complex internal shape includes providing a core of a shape that defines an internal cavity of an actuator; molding an actuator around the core, wherein the core occupies the internal cavity of the actuator, the cavity having an opening; generating a pressure differential between an exterior surface of the actuator and the internal cavity of the actuator, wherein the external pressure is less than the internal pressure, to expand the actuator cavity; and removing the core through the opening of the expanded actuator cavity. |
| US10780590B2 |
Apparatus, system, and method for relocating data-center modules
A data-center-module relocation device may include a plurality of interchangeable end effectors, including at least one module relocation effector that is dimensioned to hold data-center modules. The device may also include a robotic arm with a distal end adapted to switch between the plurality of interchangeable end effectors and select the module relocation effector as an active end effector for the robotic arm. In addition, the device may include an actuator that moves the robotic arm to cause the robotic arm to relocate, from one location in a data center to another location in the data center, a data-center module held by the module relocation effector. Various other apparatuses, systems, and methods are also disclosed. |
| US10780585B2 |
Robot and electronic device for performing hand-eye calibration
A robot for performing hand-eye calibration is provided. The robot includes a robot arm including a plurality of joints, a plurality of arm sections, and an end effector, a communication interface, and a control circuit. The control circuit controls the robot arm to place the external object on a worktable after the external object is grasped by the end effector, acquires coordinates of a central point of the external object in a coordinate system of the camera from an image of the external object, and calculates a calibration parameter for defining a relation between a coordinate system of the end effector and the coordinate system of the camera, based on coordinates of the end effector in a base coordinate system of the robot and coordinates of the central point of the external object in the coordinate system of the camera when the external object is placed on the worktable. |
| US10780580B2 |
Teaching apparatus used for operation of industrial robot
A teaching apparatus that is connected to a control apparatus controlling a welding robot and outputs a command intended for the welding robot to the control apparatus is provided. The teaching apparatus includes a welding-parameter-manipulating portion provided on a front face and accepting an operation of changing a setting that defines a movement, of the welding robot, an enabling switch provided on a back face and accepting an operation of changing a state of electrification of the welding robot, and a robot-manipulating portion provided on the back face and accepting an operation of executing the movement of the welding robot. The welding-parameter-manipulating portion is positioned on a left side, in front view, with respect to the center, and the enabling switch and the robot-manipulating portion are positioned on a right side, in rear view, with respect to the center. |
| US10780579B2 |
Work robot system
A work robot system including a conveying apparatus that conveys an object in one direction; a robot that performs a predetermined task on a target portion of the object being conveyed by the conveying apparatus, a movement amount detector that sequentially detects the movement amount of the object moved by the conveying apparatus, and a force detector that detects a force generated by contact between a tool supported by the robot and the object. Then, when the predetermined task is performed, a controller performs force control based on a value detected by the force detector while performing control of the robot by use of information about the position of the target portion and a value detected by the movement amount detector. |
| US10780578B2 |
Reaching mobile robots
A method of operating a robot includes driving a robot to approach a reach point, extending a manipulator arm forward of the reach point, and maintaining a drive wheel and a center of mass of the robot rearward of the reach point by moving a counter-balance body relative to an inverted pendulum body while extending the manipulator arm forward of the reach point. The robot includes the inverted pendulum body, the counter-balance body deposed on the inverted pendulum body, the manipulator arm connected to the inverted pendulum body, at least one leg having a first end prismatically coupled to the inverted pendulum body, and the drive wheel rotatably coupled to a second end of the at least one leg. |
| US10780577B2 |
Machine learning device, robot system, and machine learning method for learning operations of robot and laser scanner
A machine learning device for learning operations of a robot and a laser scanner, includes a state observation unit observing a state of a tip end of the robot where the laser scanner is mounted and a state of an optical component in the laser scanner as a state data; a determination data obtaining unit receiving at least one of a machining time of the robot where the laser scanner is mounted, a drive current driving the robot, a command path of the laser scanner, a passing time in a processable area where the laser scanner performs processing, and a distance between the robot and a part where the laser scanner performs processing as a determination data; and a learning unit learning operations of the robot and the laser scanner based on an output of the state observation unit and an output of the determination data obtaining unit. |
| US10780575B2 |
Robot end effector cuff
A robotic system including a robot and an end effector cuff connected to the robot. The end effector cuff has a body and includes at least one fluid inlet, at least one fluid port fluidly connected to the at least one fluid inlet, at least one fluid valve fluidly connected to the at least one fluid port and housed within the body of the end effector cuff, and an electronic control unit operably coupled to the robot and housed within the body of the end effector cuff. The robotic system also includes an end effector connected to the end effector cuff. |
| US10780570B2 |
Surface-treatment appliance
Surface-treatment appliance having a base arrangement, which in a functional position can be displaced on a surface which is to be treated, and having a guide part articulated on the base arrangement and intended for controlling the base arrangement manually. An arcuate guide is provided on the base arrangement, on which can be displaced in a linear manner a carriage body. The carriage body is connected to the guide part and is supported on the arcuate guide, at least in the radial direction, by at least two supporting points, which are spaced apart from one another along the arcuate guide. |
| US10780569B2 |
Knife having adjustable handle
A knife handle assembly adapted for attachment to a knife blade, including an elongated handle having a cavity formed therein and a pliable section positioned adjacent the cavity; an elongated rod extending along a longitudinal axis and into the cavity; a user engageable member attached to the rod on the exterior of said handle and adapted to permit selective rotation of the rod about its longitudinal axis; and a first cam positioned within the cavity and in abutting relation to the pliable section and engaged with the rod, wherein rotation of the rod about its longitudinal axis translates to movement of the first cam into said pliable section an amount corresponding to the degree of rotation. |
| US10780567B2 |
Accessory attachment for driven fastener hand tool
An accessory attachment for a driven fastener hand tool is disclosed comprising a mounting block having an attachment channel and an indexing guide feature. A plate for covering a fastener driving channel of the fastener tool has a nose end with chamfered edges on opposing sides towards the fastener driving channel and the attachment channel has opposing lips for seating against the chamfered edges of the nose end of the plate. One or more bolts through the mounting block at a bottom of the attachment channel press the nose end of the plate causing the opposing lips of the mounting block to press against the chamfered edges thereby securing the mounting block to the nose end of the plate. Alternately or additionally, the mounting block can be used to support a range of accessories including, a non-marring pad, a light, such as an LED, a level, and/or an edge guide. |
| US10780566B2 |
Pneumatic tool
A pneumatic tool includes a main body unit, a control valve unit, a switch unit and a trigger unit. The main body unit has a flow path for guiding inflow of air. The control valve unit removably blocks the flow path. The switch unit includes a sleeve member movable between an open position where the control valve unit is driven to unblock the flow path, and a block position where the control valve unit is driven to block the flow path. The trigger unit includes a trigger member operable to move the sleeve member between the open position and the block position. |
| US10780565B2 |
Housing device for a hand-held power tool
A housing device for a hand-held power tool includes at least one receiving interface configured to receive a battery unit. The at least one receiving interface is further configured to receive a mains power connection unit as an alternative to the battery unit. |
| US10780561B2 |
Detaching tool
Embodiments of the present invention provide a detaching tool The detaching tool includes a detaching plate. A detaching part of the detaching plate is adapted to be inserted between a printed circuit board and a backlight source back plate. The detaching tool is configured to separate and detach the PCBA, adhered to the backlight source back plate, from the backlight source back plate. |
| US10780557B2 |
Slugging wrench
The present invention relates to a slugging wrench for exerting slugging force on a fastening member such as a nut during tightening or loosening thereof, the slugging wrench comprising: an arm, an impact absorbing element arranged on the arm for absorbing the slugging force, a receiving member for receiving the fastening member, wherein the receiving member is provided with an inner surface fitting in force-transmitting manner on an outer surface of the fastening member and preferably having in a view, such as in the in-feed direction, a shape such as a polygon, such as a hexagon, such as a dodecagon, wherein the inner surface is provided with two grooves suitable for receiving a clamping member for the purpose of providing a clamping action in respect of the fastening member. |
| US10780556B2 |
Anti-slip, multidirectional driver bit
A screw bit body which allows for efficient torque force application onto a socket fastener. The screw bit body includes a plurality of laterally-bracing sidewalls, a first base, and a second base. The laterally-bracing sidewalls are radially distributed about a rotation axis of the screw bit body with each further including a first lateral edge, a second lateral edge, a bracing surface, and an engagement cavity. The engagement cavity creates an additional gripping point to prevent slippage in between the screw bit body and the socket fastener. The engagement cavity traverses normal and into the bracing surface. Additionally, the engagement cavity traverses into the screw bit body from the first base to the second base. The engagement cavity is specifically positioned offset from the first lateral edge by a first distance. |
| US10780555B2 |
Combination of control cabinet keys
The invention relates to a combination (1) of control cabinet keys (2), individual keys being situated in the same plane but extending at a fixed angle (x) relative to one another and connected via a common center part (4, 5). Due to the fixed connection between the keys, during handling, a torque may be applied to a key (2) that is used. For ease of handling, a first unit (E1) and a second unit (E2) of keys extending at a fixed angle (x) relative to one another are provided, all units (E1, E2) have their own center part, and the units are detachably connected at their center parts (4, 5), and/or the keys are rotatable relative to one another, but only in a respective predefined plane. |
| US10780549B2 |
Polishing device
A polishing device configured to polish a glass substrate is disclosed, including a polishing wheel fixedly arranged, a cooling pipe, and a movable platform. The polishing wheel has an outer peripheral polishing surface, the glass substrate is placed on the platform and is driven by the platform to move so as to make the outer peripheral polishing surface polish the predetermined polishing surface of the glass substrate; the polishing wheel further has a chamber, and the cooling pipe containing a coolant is disposed in the chamber to decrease a temperature of the chamber and then to make temperatures of the outer peripheral polishing surface and the predetermined polishing surface during polishing is lower than a preset temperature. The disclosure solves the problem of high polishing temperature of the polishing wheel and the glass substrate, thereby enhancing the service life of the polishing wheel and the yield of the glass substrate. |
| US10780535B2 |
Automatic screw tightening module and robot manipulator employing same
An automatic screw tightening module includes a plate assembly, an input module, a screwdriver module, a transmission module, a movable module, an elastic element and a position sensor. The screwdriver module includes a screwdriver and a screwdriver sleeve. The transmission module is connected with an input terminal of the input module and the screwdriver sleeve for allowing the input terminal, the transmission module and the screwdriver sleeve to be rotated synchronously. The movable module is movably disposed on a base plate of the plate assembly. The movable module includes a bearing, and portion of the screwdriver sleeve is accommodated in the bearing, so that the screwdriver module and the movable module are moved relative to the base plate. The elastic element is disposed on the base plate and connected with the movable module. The position sensor is disposed on the base plate for sensing a displacement of the movable module. |
| US10780533B2 |
Component having wear-protected openings and recesses and process for the production thereof
The present invention relates to a method for producing and/or repairing wear-stressed recesses or openings on components (22) of a turbomachine, especially of elements of a flow passage boundary, and also to corresponding components, wherein the method comprises:producing an at least two-layer molded repair part (15), one layer (2) of which is formed by an Ni-solder and a further layer (3) of which is formed from a mixture of an Ni-solder (4) and hard material particles (5) of hard alloys on a base of cobalt or nickel and which at least partially has an outer shape which is complementary to the inner shape of the recess (20) or opening which is to be repaired,inserting the molded repair part (15) into the recess (20) or opening andat least partially heat-treating the component (22) for soldering the molded repair part (15) onto the component. |
| US10780524B2 |
Laser processing method and laser processing apparatus
Disclosed herein is a laser processing method including a first application step of applying a first laser beam having a pulse width shorter than time of electron excitation generated by application of a laser beam to a workpiece, and a second application step of applying a second laser beam within the electron excitation time. |
| US10780523B1 |
Eddy current monitoring in an additive manufacturing continuous welding system
An AM continuous welding system (AMCWS) is provided. The AMCWS includes a feedstock dispenser that configured to emit feedstock at a designated location, and a heat source configured to heat the feedstock. The AMCWS also includes a first eddy current sensor array that is configured to generate a first plurality of sensor signals while in current-sensing proximity of a re-solidified feedstock segment. A controller is coupled to the first eddy current sensor array and is configured to determine, based on the first plurality of sensor signals, a first characteristic of the re-solidified feedstock segment. The controller determines that the first characteristic is a first undesirable characteristic, and initiates an action based on the first undesirable characteristic. |
| US10780521B2 |
Metal composite and metal joining method
A metal composite and a metal joining method that are capable of suppressing an influence on joining strength of a friction stir welded section due to a tool hole formed when a tool is extracted, in the case in which two metals are joined through friction stir welding. In an overlapping section in an axial direction in which a first shaft and a second shaft overlap in the axial direction, an inscribed section in which the first shaft and the second shaft come in contact with each other and an non-inscribed section in which the first shaft and the second shaft do not come in contact with each other are formed. In the non-inscribed section, a plate thickness of the second shaft is decreased. Then, a starting point of a friction stir welded section is formed in the inscribed section, and an endpoint is formed in the non-inscribed section. |
| US10780519B2 |
Integrated resistance welding of functional element and auxiliary element
The invention relates to a method for joining at least one sandwich sheet to at least one functional element made of metal, wherein the at least one sandwich sheet has two metallic outer layers and a thermoplastic layer arranged between the metallic outer layers, wherein at least the region to be joined of the at least one sandwich sheet is heated in such a manner that the thermoplastic layer softens, the plastic layer is pushed out of the joining region by the outer layers being pressed together, and the outer layers of the at least one sandwich sheet are joined, in particular welded, to the functional element by an electric current flow between a first and a second electrode. |
| US10780516B2 |
Wave solder nozzle with automated adjustable sliding plate to vary solder wave width
A wave soldering machine includes a housing and a conveyor configured to deliver a printed circuit board through the housing. The wave soldering machine further includes a wave soldering station coupled to the housing. The wave soldering station includes a reservoir of solder material, and a wave solder nozzle assembly configured to create a solder wave. The wave solder nozzle assembly has a nozzle core frame, a solder distribution baffle secured to the nozzle core frame, and a sliding plate that together define a nozzle. The sliding plate is movable with respect to the nozzle core frame between a close proximate position in which the nozzle is configured to produce a reduced width solder wave through the solder distribution baffle and a spaced apart position in which the nozzle is configured to produce an extended width solder wave through the solder distribution baffle. |
| US10780515B2 |
Auto-adaptive braze dispensing systems and methods
Systems and methods for moving a substrate to a vision system using a robot; using the vision system to determine where a braze material is to be applied to the substrate; moving the substrate to a braze dispenser using the robot; applying a braze material to the substrate using the braze dispenser based on the determination from the vision system; and using the vison system to determine whether to apply additional braze to the substrate, including for the substrate of a component for gas turbine engine, such as configured for use in an aircraft. |
| US10780498B2 |
Porous tools and methods of making the same
A porous tool includes a mold body and an additively-manufactured film attached to a surface of the mold body. The film includes a porous layer and a nonporous support layer. The porous layer may include a surface having an array of surface pore openings, a network of interconnected passages in fluid communication with the surface pore openings, and one or more lateral edges that have an array of edge pore openings in fluid communication with the interconnected passages. Methods of forming a porous tool include depositing additive material on a build surface using a directed energy deposition system to form a film while simultaneously subtracting selected portions of the additive material from the film using laser ablation. Methods of forming a molded component include conforming a moldable material to a shape using a porous tool that includes a mold body and an additively-manufactured film, and evacuating outgas from the moldable material through a porous layer of the film. |
| US10780491B2 |
Aluminum casting design with alloy set cores for improved intermetallic bond strength
A method of forming an assembly is provided. The method includes forming an insert, coating the insert with a bond material and placing the insert within a casting mold or die. The casting mold or die is purged with an inert gas and the casting mold or die is filled with molten metal to encapsulate the insert. The encapsulated insert is diffusion bonded to the molten metal to form a diffusion bonded insert, which is placed within a cavity of a secondary casting mold or die. The secondary casting mold or die is filled with molten metal to form a composite casting assembly. After or during the casting, the composite casting assembly is heat treated. In another method of the present disclosure, the insert includes ferrous alloys, nickel-based alloys, super alloys, and nonferrous alloys. |
| US10780489B2 |
Tool-free opening tape feed receiver for a self-piercing rivet machine
A self-piercing rivet tape path can extend through a clamshell receiver assembly between the upper and lower receiver bodies and can open between the upper and lower bodies along a longitudinal length of the self-piercing rivet tape path that extends through the clamshell receiver assembly. The upper and lower bodies can separate at a lead rivet cavity and above a proximal end of a discharge cavity of the lower body. A tool-free interlock coupling can rigidly couple the upper and lower receiver bodies together in a closed position. This tool-free coupling can unlock the upper and lower receiver bodies so they are hingedly movable into the open position. The clamshell receiver assembly can be rigidly coupled to an end of a self-piercing rivet spindle to receive self-piercing rivets carried by the tape along the tape path and support a lead self-piercing rivet in alignment with a punch of the spindle. |
| US10780485B2 |
Die cushion device
To provide a die cushion device which is inexpensive, functional, and capable of locking completely (at or below the slide bottom dead center). The die cushion device includes a cushion pad, a hydraulic cylinder that moves the cushion pad up and down, and a hydraulic closed circuit connected to a die cushion pressure generation chamber of the hydraulic cylinder. The hydraulic closed circuit includes a cushion pad lowering pressure generation line and a second system pressure line in addition to a die cushion pressure generation line and a first system pressure line. When the cushion pad is locked at the bottom dead center, the cushion pad lowering pressure generation chamber is connected to the first system pressure line, and the die cushion pressure generation chamber is connected to the second system pressure line such that the cushion pad is held at or below the slide bottom dead center. |
| US10780484B2 |
Processing method and apparatus for metal housing
A processing method and a processing apparatus for a metal housing are provided. The method includes: sleeving a metal flat pipe having an end face provided with a curved surface portion on a lower mold; and pressing the curved surface portion by the cooperation between an upper mold and the lower mold, thereby forming a chamfered slanted surface on the curved surface portion. The processing processes and the apparatus involved are simple, the quality of the products is improved, and thus the method may be suitable for mass production. |
| US10780483B1 |
Curving tool for wall and ceiling framing members
A tool for shaping wall and ceiling framing members includes a frame and a plate that is adjustable with respect to the fame. A fulcrum is repositionable with the plate to predetermined locations that permit bending of the wall or ceiling framing member about the fulcrum. The member is shaped by placing a first portion of the member at the first end of the frame, placing a second portion of the member at the fulcrum, and bending the member about the fulcrum. To obtain an accurate shaping to the member, the member may be bent about the fulcrum until a third portion contacts a second end of the frame, wherein the fulcrum is between the first and second ends of the frame. |
| US10780475B2 |
Lubrication using spray nozzles having multiple oil inlet openings
During the rolling of a metallic flat rolling stock (1) in a roll stand (2), lubricating oil (5) is sprayed onto the rolling stock (1) and/or at least one roll (3,4) of the roll stand (2) by multiple spray nozzles (7) arranged beside one another. In each case, a mixing chamber (8) of a spray nozzle (7) is fed with a respective quantity of lubricating oil (5) via respective multiple oil inlet openings (9). The respective mixing chamber (8) is fed with compressed air (11) via respectively one air inlet opening (10). Compressed air (11) atomizes the lubricating oil (5) in the respective mixing chamber (8) to form an aerosol and, via respectively at least one nozzle outlet (12), is sprayed onto the rolling stock (1) and/or the at least one roll (3,4) of the roll stand (2). |
| US10780472B2 |
Systems, devices, controllers, and methods for use in the treatment of a pipeline
System and method for decommissioning a pipeline. The system comprises mechanical and chemical assemblies. The mechanical assembly includes a main body and a contact assembly. When the mechanical assembly is provided in the pipeline, the contact assembly is configurable to contact with the interior wall of the pipeline. The chemical assembly is arranged serially in line with the mechanical assembly. The chemical assembly includes a front section having a cross-sectional portion and a rear section having a cross-sectional portion. The front and the rear section are arranged in such a way that the cross-sectional portions of the front and the rear section cooperate with the interior wall of the pipeline to form a chamber to house a removal medium. The system and method can effectively and efficiently remove most or all of such residual mercury and/or other toxic substance from the interior wall of the pipeline before abandonment. |
| US10780470B2 |
Device and method for connecting in a switchable manner
An apparatus has a plurality of inlet ports each connectable to a material supply container and an outlet port. A disk-shaped valve body has a first side and an opposite second side with a straight throughgoing passage from the first side to the second side, the body being displaceable relative to the inlet ports to provide a switchable connection between a respective one of the plurality of inlet ports and the outlet port. The passage can be also be connected with a respective one of the various inlet ports to enable feeding of different materials successively to the outlet port. One of the inlet ports is a flushing medium inlet port of a flushing device, and the passage can connected with the flushing medium inlet port by displacement of the valve body for flushing the passage. |
| US10780469B2 |
System for laser treating a pipe surface
A laser cleaning system for laser treating a pipe surface includes a frame mountable to an outer circumference of a cylindrical pipe, a plurality of circumferential guide supports mounted to the frame and engageable with the outer circumference of the pipe, and a laser mounted to the frame to generate a laser beam directed toward an exterior surface of the pipe. The frame is movable about the outer circumference of the pipe on the plurality of circumferential guide supports to scan the laser beam circumferentially across the exterior surface. |
| US10780468B2 |
Cleaning device and cleaning method
The present disclosure discloses a cleaning device and a clean method, the cleaning device includes a sweeping module and a washing module, the sweeping module includes a brush component and a steam generating component, the steam generating component and the brush component are arranged in sequence in the cleaning direction of the cleaning device; the washing module is configured to wash the parts to be cleaned, the washing module and the sweeping module are arranged in sequence in the cleaning direction of the cleaning device. |
| US10780464B2 |
Powder suction and removal apparatus and powder suction and removal method
A suction and removal apparatus which removes highly active pharmacological substances attached to the garments that can re-scatter when changing the clothes and prevents the leakage of such powder to the external environment. The suction and removal apparatus is for sucking and removing in a closed room powder attached to the garments of a person, and includes a suction device, a suction head containing a high efficiency particulate air (HEPA) filter and having a suction port, and a flexible tube connected between the suction device and the suction head. The suction port of the suction head has a cap that closes the suction port, the connection between the suction head and the flexible tube is attachable and detachable, and the suction device is installed outside or inside the room and the suction head and part of the flexible tube are installed inside the room. |
| US10780463B1 |
Multiphase liquid cleaning system
A cleaning system and wherein one or more surface cleaning devices use high-pressure, high-temperature water from a pressure module for surface cleaning, and wherein the waste water resulting from the surface cleaning is recovered, and wherein the solid waste matter within the waste water is filtered and separated into solid waste matter and clean filtered water, wherein the filtered water is reused by the cleaning apparatus and the solid waste matter is available in a form that can be disposed of by traditional means. |
| US10780461B2 |
Methods for processing substrate in semiconductor fabrication
A method of processing a substrate in semiconductor fabrication is provided. The method includes supplying a mixture to a process module. The method further includes detecting the concentration of a substance in the mixture. The method also includes dispensing the mixture over a substrate in the process module. In addition, the method includes supplying a supply solution including the substance to the process module and dispensing the supply solution over the substrate if the concentration of the substance in the mixture is less than a desired value. |
| US10780459B2 |
System and tool for cleaning a glass surface of an accelerator column
A cleaning tool for cleaning a glass surface of an accelerator column is disclosed. The cleaning tool includes a shaft including a first end and a second end; a foam body located at the first end of the shaft; and a mounting bracket coupled to the first end of the shaft, the mounting bracket receiving the foam body. An outer circumference of the foam body includes a textured cleaning surface for contacting the glass surface of the accelerator column. |
| US10780456B2 |
Method and jig for forming pattern using magnetic ink and magnetic force
The present invention relates to a method and a jig for forming a pattern, the method and the jig being capable of realizing various and unique pattern designs due to magnetic particles included in the magnetic ink being distributed in various densities according to intensity of the magnetic force. Disclosed is a method and a jig for forming a pattern by using magnetic ink and magnetic force, the method including: preparing a jig which generating magnetic force, applying magnetic ink on a surface of a substrate to form a print layer, disposing the substrate configured with the print layer above the jig, forming a magnetic pattern on the print layer by applying magnetic force generated from the jig, and drying the print layer. |
| US10780454B2 |
Sealant applicator and methods of use
A sealant applicator nozzle, of the present technology, has a fan-shaped profile, with a broad concave arc that defines a distal end of the nozzle and provides the nozzle with a tooling edge. The concave tooling edge, along with the outlet orifice, and two surface-contact edges are positioned to equidistantly straddle a lap joint to be sealed when in operation. In methods of using the nozzle, a wide ribbon of sealant is applied in a smoothly arched geometry, forming a segment of a circle, over a lap joint so that the thickest part of the arch is centered directly on the edge of the overlapping material that forms the lap joint. |
| US10780450B2 |
Water delivery device
A water delivery device is described which includes an outlet pipe through which water is ejected to provide a water display. A disk is positioned relative to the outlet pipe. The relative positions of the disk and outlet pipe are moved so that the disk is located within the outlet pipe or above it to alter the appearance of the water leaving the outlet pipe. As the relative position of the disk and outlet pipe varies, a sequence of water expressions is provided. |
| US10780445B2 |
Separator with inner and outer drum and one or more grippers having a disk portion and a shank portion
A separator for centrifugally processing a flowable product includes a rotatable drum bounding a centrifuging chamber. The drum has a feeding and removal system having at least one feeding device and one or more removal devices composed of plastic or a plastic composite. An inner drum, composed of plastic or a plastic composite, is arranged in an outer supporting device of the drum. The feeding device and the one or more removal devices extend into the inner drum, do not rotate with the inner drum during operation, and are glued and/or welded to each other in such a way that the feeding device and the one or more removal devices are sealingly connected. The feeding and removal system has one or more grippers as the removal device, each of which one or two or more grippers has a disk segment and a shaft segment. |
| US10780440B2 |
Anti-spin apparatus and method for cone crusher head
A method and apparatus for counteracting spin of the crusher head on cone or gyratory crushers is provided. An annular rubber muscle element is secured relative to said bowl frame and positioned between the bowl frame and a surface of the head, and which can be selectively placed into contact under pressure with the surface of the head to prevent spin during start up but which is then released during normal crushing operation. |
| US10780433B2 |
Acid composition for processing fatty acids
The invention relates to a composition comprising: at least one alkane-sulphonic acid R—SO3H wherein R represents a saturated, linear or branched, hydrocarbon chain comprising from 1 to 4 carbon atoms, which can or cannot be substituted by at least one halogen atom, at least one aryl-sulphonic acid; and optionally at least one solvent, of which the proportions are as defined in the description. The invention also relates to the use of composition in a fatty acid esterification method. |
| US10780427B2 |
Selective ammoxidation catalysts
A catalytic composition useful for the conversion of an olefin selected from the group consisting of propylene, isobutylene or mixtures thereof, to acrylonitrile, methacrylonitrile, and mixtures thereof. The catalytic composition comprises a complex of metal oxides comprising bismuth, molybdenum, iron, cerium and other promoters, with a desirable composition. |
| US10780424B2 |
Crush strength and porosity of an alumina carrier for enhanced VAM catalysts
Disclosed is a supported catalyst for the preparation of vinyl acetate monomer, a process for preparing the supported catalyst in tablet or pellet form, and a catalytic process for the manufacturing vinyl acetate using the supported catalyst. Specifically, it is shown that catalyst performance shows a strong dependence on the crush strength of the tableted or pelletized alumina support used in the process to make the catalyst, and that the crush strength of the catalyst is closely related to the porosity of the support. Catalyst activity and selectivity can be enhanced by tailoring the crush strength of the support. |
| US10780421B2 |
Aerosol processing method for controlled coating of surface species to generate catalysts
A method of producing a catalyst comprises generating an aerosolized flow of catalyst support particles, heating a catalytically active compound precursor to produce a catalytically active compound precursor vapor, contacting the aerosolized flow of catalyst support particles with the catalytically active compound precursor vapor, and condensing the catalytically active compound precursor onto the catalyst support particles to produce the catalyst comprising catalytically active compound deposited on surfaces of the catalyst support particles. The method may further comprise aerosolizing a catalyst support precursor mixture, drying the aerosolized catalyst support precursor mixture in a first heating zone to form an aerosolized flow of catalyst support particles, and contacting the catalyst support particles with a catalytically active compound precursor vapor in a second heating zone to form the catalyst comprising the layer of the catalytically active compound deposited on surfaces of the catalyst of catalyst support particles. |
| US10780420B2 |
Heterogeneous catalysts
Heterogeneous catalysts with optional dopants are provided. The catalysts are useful in a variety of catalytic reactions, for example, the oxidative coupling of methane to C2+ hydrocarbons. Related methods for use and manufacture of the same are also disclosed. |
| US10780419B2 |
Non-noble element catalysts and methods for making
Disclosed are non-noble element compositions of matter, structures, and methods for producing the catalysts that can catalyze oxygen reduction reactions (ORR). The disclosed composition of matter can be comprised of graphitic carbon doped with nitrogen and associated with one or two kinds of transition metals. The disclosed structure is a three dimensional, porous structure comprised of a plurality of the disclosed compositions of matter. The disclosed structure can be fashioned into an electrode of an electrochemical cell to serve as a diffusion layer and also to catalyze an ORR. Two methods are disclosed for producing the disclosed composition of matter and structure. The first method is comprised of two steps, and the second method is comprised of a single step. |
| US10780410B2 |
Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients
Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product. |
| US10780407B2 |
Method and shaker for mixing liquids
To sum up, by using the shaker for mixing liquids (1-7) (e.g. shampoo, soap, etc) with water right before use, an optimal dose of the liquid is used and appropriate solution is used. A dissolved mixture is applied to the hair/body to most significant part immediately—the hair roots and the scalp. It works beneficial for the hair, especially the hair ends, preventing dry and split ends as the e.g. shampoo is not applied directly. The mixture is distributed more evenly throughout the hair, without adding additional water and washing out the unused shampoo. The foam evolves quicker and is greater, which makes the washing easier. The shaker enables the user to use multiple liquids at once if needed. The amount of the liquid used is decreased to an optimal dose for the user and is therefore also eco-friendly, as no excessive amount of liquid is used. The invention enables the user to close tap water/shower during use and therefore uses less water and is eco-friendly. With same advantages the shaker is used in pet care and with other liquids. |
| US10780405B2 |
Liquid dispensing and aerating system
A liquid dispensing device and system to dispense, or aerate and dispense a liquid such as wine through a spout. The dispensing device having multiple air ports and aeration chambers to form multiple aerating segments during the pour process. The dispensing device having a handle to increase grasping of a liquid container and preventing accidental separation of the device and a container. |
| US10780404B2 |
Polyaniline membranes, uses, and methods thereto
Disclosed herein are methods of increasing the hydrophilicity of a membrane. Membranes comprising polyaniline or co-polymer thereof and one or more gel inhibiting agents are treated with one or more hydrophilicity restoration agents, thereby increasing the hydrophilicity of a membrane. Also disclosed are membranes produced by the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| US10780402B2 |
Methods of membrane modification
A method of manufacturing a membrane can include forming the membrane from a dissolved polymer in the presence of a functionalizing agent; and exposing the functionalizing agent to a nanoparticle to form a modified membrane. |
| US10780400B2 |
Agent, liquid, and method for cleaning reverse osmosis membrane
Provided is an agent and a liquid for cleaning an RO membrane to remove effectively foulants that can not be sufficiently removed with conventional cleaning agents when an RO membrane particularly an aromatic polyamide RO membrane has been used for water treatment and has become fouled resulting in degradation of performance such as permeation flux, pressure difference, and salt rejection rate. The agent for cleaning an RO membrane includes an aliphatic amide and/or an aromatic amide. Also provided is a method for cleaning an RO membrane with the cleaning agent or the cleaning liquid. The aliphatic amide and/or the aromatic amide particularly an aliphatic amide and/or an aromatic amide being soluble in water and having a relatively low molecular weight remove effectively foulants adhered on an aromatic polyamide RO membrane. |
| US10780397B2 |
Base metal catalyst for treatment of ozone and volatile organic compounds present in air supply
Disclosed herein are base metal catalyst devices for removing ozone, volatile organic compounds, and other pollutants from an air flow stream. A catalyst device includes a housing, a solid substrate disposed within the housing, and a catalyst layer disposed on the substrate. The catalyst layer includes a first base metal catalyst at a first mass percent, a second base metal catalyst at a second mass percent, and a support material impregnated with at least one of the first base metal catalyst or the second base metal catalyst. |
| US10780395B2 |
Pollutant treatment process and apparatus
A process for removing hydrocarbons from a feed stream containing hydrocarbons includes introducing ozone to the feed stream to produce an ozone doped stream containing ozone and hydrocarbons, and contacting the ozone doped stream with a supported metal catalyst at a temperature of from 100° C. to 300° C. to produce a treated stream, wherein the supported metal catalyst comprises iron supported on a support selected from aluminosilicates, silica-aluminas, silicates and aluminas. A process for removing NOx from a feed stream containing NOx, and an apparatus for removing hydrocarbons and/or NOx from a feed stream containing hydrocarbons and/or NOx are also provided. |
| US10780394B2 |
Compositions and methods for removing air pollutants
Compositions for removing air pollutants from the air are provided. These compositions can be sprayed on a variety of surfaces to remove air pollutants such as volatile organic compounds (VOCs) from the environment, and are suitable for use in human dwellings. |
| US10780386B2 |
Liquid film dust arrester and flue gas desulfurization system
A liquid film dust arrester is installed to face a gas flow containing dust and flowing out from a gas discharge pipe. The arrester includes a gas flow blocking unit arranged vis-à-vis the gas flow, a liquid dispersion unit having a dispersion section arranged at a position near the center of the gas flow blocking unit and upstream relative to the gas flow blocking unit as viewed in the flowing direction of the gas flow so as to face the gas flow blocking unit, a liquid ejection unit having an ejection port disposed vis-à-vis the dispersion section and configured to eject liquid from the ejection port, and a liquid film forming unit. The dispersion section comprises a smooth surface that causes the ejected liquid to flow and disperse on the smooth surface, and the liquid film is formed to face the gas flow flowing through the flow path. |
| US10780385B2 |
System and method for condition-based monitoring of filters
In one embodiment, a system includes an intake section including a filter and one or more strain gauges. The system also includes a processor configured to receive strain information for the filter from the one or more strain gauges and determine an operating condition of the filter based at least in part on the strain information. |
| US10780384B2 |
Portable system and methodology that facilitates dust collection within a silo apparatus
Aspects for dust collection are disclosed. In one aspect, an apparatus is disclosed, which includes a lightweight portable housing such that a vacuum source, a filter component, and a dust containment component are housed within the lightweight portable housing. The apparatus further includes an input component configured as a conduit between the lightweight portable housing and a dust transition area corresponding to an area between a dust loading component and a dust receiving component. The vacuum source is configured to apply a negative pressure to the dust transition area by creating an air flow from the dust transition area to the lightweight portable housing via the input component, whereas the dust containment component is configured to collect airborne dust removed from the dust transition area and filtered by the filter component. Similar apparatuses are also disclosed to facilitate dust removal from a silo, as well as from a mixer. |
| US10780382B2 |
Filter module and device for the separation of overspray, and plant having the same
A filter module for the separation of overspray from overspray-laden cabin air of coating plants, in particular of painting plants, having a filter housing which delimits a filter chamber through which overspray-laden cabin air can be conducted in a main flow direction. A plurality of separation elements composed of a separation material which is permeable to the cabin air is arranged in the filter chamber such that a flow labyrinth is formed between the separation elements. A separation device and a plant for coating articles having such a filter module is also provided. |
| US10780381B2 |
Pattern coated filter and method
The present technology is generally related to a filter assembly. The filter assembly has a first layer has a base layer defining a first perimeter region and a region central to the first perimeter region. A first adhesive is disposed on a first surface of the first layer substantially within the central region, and first adsorbent beads are coupled to the first adhesive. A second layer has a first sheet of filter material having a second perimeter region, wherein the first perimeter region and the second perimeter region are bonded. A third layer has a second sheet of filter material having a third perimeter region, wherein the first perimeter region and the third perimeter region are bonded. The base layer, second layer, and third layer are substantially coextensive. |
| US10780377B2 |
Sanitizing filter system and method for a residential water filtering system
A sanitizing filter for sanitizing a residential water filtering system has a water filter assembly including a cartridge operable for removable attachment to the water filter assembly. When the cartridge is attached to the water filter assembly, a water flow passes into the cartridge, mixes with sanitizing media within the cartridge, and passes back into the water filter assembly. The residential water filtering system is then filled and flushed repeatedly and the mixture of water and sanitizing media sanitizes the portions of the system that are downstream from the sanitizing filter. |
| US10780373B2 |
Hollow fiber degassing module, and method of degassing liquid using said hollow fiber degassing module
A hollow fiber degassing module includes: a cylinder; a first lid having a liquid supply port; a second lid; a liquid inflow portion that includes a cylindrical main body being in communication with the liquid supply port inside the cylinder; a hollow fiber membrane bundle that is provided inside the cylinder and that includes multiple hollow fiber membranes; a liquid outlet; a first air outlet that is provided to any one of the first lid and the second lid and connected to the inside of the hollow fiber membranes; and a bubble outlet that is provided to the cylinder. |
| US10780361B2 |
Collision judgment system, method, apparatus, and device
The present disclosure provides a collision judgment method and apparatus. The method includes: determining, by a moving device, according to acceleration data collected by an acceleration sensor, that the moving device collides; sending collision information to the corresponding control device, including at least a moving device identifier and a collision time; sending, by the corresponding control device, the collision information to a collision judgment device; detecting, by the collision judgement device, whether at least two collision information sent by the at least two control devices is received within a predetermined time interval; when the at least two collision information is received within the predetermined time interval, and a difference between collision times carried in the at least two collision information is less than a preset threshold, determining that moving devices corresponding to moving device identifiers carried in the at least two collision information collided with one other. |
| US10780358B1 |
Virtual reality arena system
A virtual reality (VR) arena and related methods are disclosed. In one embodiment, the VR arena includes an enclosure and at least one support that is attached to the enclosure. The enclosure encloses a user action regions. Furthermore, the enclosure and at least one support define a wiring track around the enclosure. In this manner, a user can be maintained within the user action region while a VR system is in use by the enclosure. Additionally, the support(s) can be used to support the VR user device(s) while the wiring track can be used to maintain the wiring for the VR user device(s) out of the user action region. |
| US10780356B2 |
Music game apparatus and method, and computer-readable recording medium recording program therefor
The present invention relates to a music game apparatus and a recording medium therefor and, more specifically, provides an operation guide note consisting of a start note, a cadence note, and a path indicated line connecting the same, and determines the success of the operation of a corresponding note only by the time interval and direction of moving the operation along the path indicated line, thereby enabling the playing of a game in accordance with a tempo of a music, and improving the interest for the game. |
| US10780354B2 |
Systems and methods for playing electronic games and sharing digital media
Various systems and methods for sharing electronic media are disclosed herein. According to particular embodiments, the system enables a user to select media (e.g., an image, a video, a gif, etc.) and compose a phrase to be associated with the media. In some embodiments, the system creates a post from the media and the phrase and enables the user to transmit the post to one or more other users to play (e.g., guess the phrase). |
| US10780347B2 |
Print system, server, print method, and program
A print system, a server, a print method, and a program capable of bringing attention to a photo print of a player of an online game and acquiring a distinctive photo print suitable for communication are provided. A smartphone displays a composite image in which a captured image imaged by a camera unit and a computer graphics image showing a character and acquired from a game server during the online game are composited on a display unit, and acquires the composite image displayed on the display unit in a case where imaging instruction information is received. In a case where print instruction information is received, the smartphone generates a print image including the acquired composite image and status information related to the character of the game and acquired from the game server, and outputs the generated print image to a printer. |
| US10780346B2 |
Server apparatus, control method for server apparatus, and program
A server apparatus for providing a game using game media to a user over a network may include a storage unit, an identifier obtaining unit, and a game content output unit. The storage unit may store identifiers and game media in association with each other. The identifier obtaining unit may obtain, from a terminal apparatus, an identifier selected through a user operation. The game content output unit may obtain a game content associated with the identifier obtained by the identifier obtaining unit and may output the game content to the terminal apparatus. The game content may not be identifiable using the identifier. |
| US10780343B2 |
Game controller
The present invention is a game controller, the game controller comprises a body, at least one socket, at least one fastening receptor, at least one actuating module, at least one fixed and at least one fastening member. The socket is formed in the body. The fastening receptor is formed in the body. The actuating module is removably mounted in the socket. The fixed frame is configured to receive the actuating module. The fixed frame comprises at least one first positioning hole. The actuating module is fixed in the socket by a combination of the fixed frame and the fastening member, wherein the fastening member passes the first positioning hole and fastens in the fastening receptor. |
| US10780341B2 |
Space maze puzzle with reconfigurable paths
A space puzzle including a plurality of outer face panels, at least two of the plurality of outer face panels each defining at least one path segment. Each of the outer face panels is rotatable, and the rotation of any one of the outer face panels is independent of and not altering any path segment defined in another of the outer face panels. The path segments on the at least two of the outer face panels of the puzzle are configured such that at least one sequence of rotations of at least one of the at least two of the outer face panels exists that permits a position indicator to travel along a continuous pathway between a preset starting point and a preset finish point along the at least one path segment of the at least two of the plurality of outer face panels. |
| US10780337B2 |
In-mouth filter against insects and particulates
An in-mouth barrier against entry of insects, pollen and particulates in to the open mouth of a user, particularly in strenuous outdoor exercises, needs to be comfortable and fully effective for various extents of an agape mouth, and ideally should require no conscious effort to re-position in even long durations. A filter frame surrounding a screen is formed to the dental arch so as to envelope both rows of teeth except possibly the molars. A flange on the frame holds the frame on the mandibular teeth and prevents the frame from moving down. The end of the flange lies under the tip of the tongue and prevents the frame from moving up. The frame thus remains comfortably inside the vestibule and covers the mouth for the various extents it may be opened to. |
| US10780335B1 |
Contact location identification apparatus and method
A contact location identification apparatus and method consists of a marking device with a first side and a second side. An attachment device is connected with the first side, where the attachment device removably attaches to an object. A marking receptor surface is provided on the second side, where the marking receptor surface holds a transferable marker substance. |
| US10780334B2 |
Zippered safety layer in a trampoline
Embodiments of the invention provide a zipper attached safety layer applied between a flexible mat and an edge pad of a trampoline. The safety layer moves with the flexible mat and prevents a user from accidently inserting an appendage into the suspension system (e.g., coiled springs) of the trampoline. Embodiments of the invention further relate to a trampoline comprising such a zippered safety layer and to a method of arranging the safety layer in a trampoline. |
| US10780331B2 |
Device for board sports and associated learning method
Some embodiments are directed to an analysis device for board sports, intended to be secured to a board, such as a surfboard or ski, at the interface with the user. The device includes: a force sensor designed to capture one or more forces generated by the user on the board; a position and motion sensor designed to capture the position, speed and acceleration of the board in space; and a processing unit or processor connected to the force sensor and to the position and motion sensor and designed to synchronize and process the data from the sensors. |
| US10780325B2 |
Golf club face insert
A resilient face insert for a golf club head, preferably a putter head, is disclosed herein. In particular, the face insert comprises a plurality of hinge features spaced from a striking surface to ensure consistent ball speed across the striking surface. At least a portion of each hinge feature extends parallel to the striking surface without making contact with the striking surface. In the preferred embodiment, each hinge feature comprises a tab portion that is spaced from the striking surface by a stem portion and that extends parallel to the striking surface. The hinge features may be co-molded with a polymeric backing material having a plurality of parallel grooves in order to further improve performance of the face insert. |
| US10780323B2 |
Golf clubs and golf club heads
Golf clubs and/or golf club heads include a club head body defining an interior chamber, structure for engaging a shaft with the body, and/or a shaft engaged with the body. The club head body may have an overall length of at least 4.5 inches and an overall breadth of at least 4.2 inches. In other examples, the club head body may have an overall length of at least 4.6 inches and a ratio of the overall breadth dimension to the overall length dimension of 1 or less. If desired, the ratio of the head breadth to head length dimensions may be in a range from at least 0.94 to 1 or less. |
| US10780322B2 |
Golf balls having layers made of silicone elastomer and polyurethane blends
Multi-layered golf balls having at least one layer made from silicone (polysiloxane) elastomers; silicone (polysiloxane) elastomer/polyurethane blends; polycarbonate-polysiloxane blends and copolymers; and polycarbonate-polysiloxane/polyurethane blends are provided. For example, three-piece, four-piece, and five-piece golf balls containing different core and cover structures can be made. The polysiloxane compositions have good thermal stability and durability without sacrificing resiliency. The polysiloxane compositions also have high elongation, tensile strength, chemical/fluid-resistance, and weatherability properties. These compositions can be used to form any layer, for example, core, intermediate, or cover, in the golf ball. |
| US10780316B2 |
Lip muscle strengthening device for preventing malocclusion and improving mouth breathing
A lip muscle strengthening device includes: an upper plate inserted into a mouth of a user including a first electrode formed on a bottom surface; a lower plate inserted into the mouth of the user including a second electrode formed on a top surface; an outer support plate adhered to an outer lip of the user and supporting a front end of the upper plate and a front end of the lower plate in a connected state while separating the upper plate and the lower plate from each other; and a pressure recognition unit connected to the first electrode and the second electrode and enabling the user to recognize a closed state of the mouth when the user pushes the upper plate and the lower plate with the upper lip and the lower lip and the first electrode and the second electrode contact each other. |
| US10780314B2 |
Exercise apparatus
An exercise device having a frame, first and second foot supports suspended on the frame by first and second linkage assemblies, one or the other or both of the frame linkage assemblies being interconnected to an adjustment device that is selectively adjustable by a user to select one of a plurality of discrete segments of a master or overall path of arcuate travel and to a lateral adjustment device that enables the user to selectively adjust a path of travel of the foot supports a selected angle relative to a central axis of the exercise device. |
| US10780313B2 |
Exercise stick
An exercise stick, including a main pole, and a tensioning assembly disposed at a substantially center portion of the main pole to move up the main pole in a first direction toward a first end of the main pole, and to move down the main pole in a second direction toward a second end of the main pole, the tensioning assembly including a large gear disposed on the tensioning assembly to change a resistance between the tensioning assembly and the main pole in response to a rotation of the large gear, and a plurality of tension clamps connected to opposing sides of the large gear to expand and contract in response to the rotation of the large gear. The tensioning assembly may further include a first worm gear to contact one of the plurality of tension clamps, and a second worm gear to contact another one of the plurality of tension clamps, such that the rotation of the large gear causes the first worm gear and the second worm gear to turn to expand or contract the plurality of tension clamps. The resistance between the tensioning assembly and the main pole may increase or decrease based on a tightening of the first worm gear and the second worm gear within the tensioning assembly, to cause the tensioning assembly to move more easily along the main pole based on a loosening of the first worm gear and the second worm gear or more difficultly along the main pole based on a tightening of the first worm gear and the second worm gear. The tensioning assembly may further include a first tension clamp having a first small gear connected to a first worm gear, the first tension clamp disposed within an inner portion of the tensioning assembly to grip a portion of the main pole, such that two upper surfaces of the first tension clamp opens or closes in response to a rotation of the first small gear, and a second tension clamp having a second small gear connected to a second worm gear, the second tension clamp disposed within the inner portion of the tensioning assembly to grip a portion of the main pole, such that two upper surfaces of the second tension clamp opens or closes in response to a rotation of the second small gear, such that the large gear is rotatably connected to the first small gear and the second small gear to control the rotation of the first small gear and the second small gear. The exercise stick may further include a handle assembly attached to the tensioning assembly to allow a user to move the tensioning assembly in the first direction and the second direction. The handle assembly may include a handle foot to attach to the tensioning assembly. The tensioning assembly may further include a handle lock disposed within a central portion of a rear surface to receive the handle foot. The handle lock may include a handle lock lever disposed within a top portion of the tensioning assembly to lock or unlock the handle foot within the handle lock, and a rotatable locking member disposed within a central portion of the handle lock to rotate in response to a manipulation of the handle lock lever, such that the handle foot is removable in the unlocked position and not removable in the locked position. |
| US10780312B2 |
Bed exercise apparatus
An exercise apparatus that may be used in a bed, primarily for stretching and resistance exercises. The exercise apparatus may be configured with a lower frame and an upper frame. The lower frame is disposed between and connected to a bed frame and a headboard. The upper frame is connected to the lower frame and has exercise equipment attachment couplers. |
| US10780308B2 |
Elastic band for use in a resistance-type exerciser
An elastic band for use in a resistance-type exerciser. The elastic band includes a continuous loop of elastic material having a pair of receiving portions and a pair of spanning portions extending between the pair of receiving portions. A cross-sectional area of each receiving portion is greater than a cross-sectional area of each spanning portion. |
| US10780307B2 |
Adjustable resistance exercise machine
An adjustable resistance exercise machine for providing variable resistance forces on a pull cable extending from the machine. The adjustable resistance exercise machine generally includes a plurality of power springs that may be selectively engaged using a cam mechanism. By engaging springs with different forces, the resistance may be adjusted incrementally as preferred for performing different exercises. The adjustable resistance exercise machine may be connected to various structures, either below or above an exerciser, to allow the exerciser to choose whether to pull the pull cable up or down during exercise. |
| US10780306B2 |
Process for the destruction of matrix material by cavitation and acid-based chemical reaction
An accelerated process for the complete destruction of a matrix material, such as a matrix material including cement and/or asbestos-containing materials (ACMs), is disclosed. The process comprises forming a slurry or suspension by combining the matrix material with an acid solution (including, for instance, acid waste, which can also be neutralized by the process), causing acid-based chemical reactions in the slurry that cause the destruction of the matrix material. Simultaneously to the chemical reactions, the slurry or suspension is subjected to cavitation, which synergistically cooperates with the chemical reactions to accelerate matrix material destruction. The matrix material can be ground and polarized prior to being submerged in the acid solution to form the slurry. The slurry can be subjected to hydrothermal treatment. Inert secondary raw materials (SRMs) that are non-hazardous to the environment and human health can be obtained from the process. |
| US10780305B2 |
Organosiloxane compounds as active ingredients in fluorine free fire suppression foams
Novel organosiloxane compounds are disclosed that are useful in firefighting foams. Methods of making and using the organosiloxane compounds and foams are also described. |
| US10780302B2 |
Fire containment system and methods of use thereof
A fire containment system strung across the ground and methods of use thereof, that generally includes two or more vertical towers anchored in series in the ground, a lift system integral to each of said two or more vertical towers having a plurality of vertically slidable swivel joints capable of vertical travel there up one of the two or more vertical towers, one or more cables, each cable strung between one of the plurality of vertically slidable swivel joints on each of the two of the or more vertical towers, a fire proof curtain affixed to said one or more cables, a below ground storage to contain said fire proof curtain. |
| US10780297B2 |
Sorting the sequential arrangement of radiation treatment beams regarding well-distributed unobstructed lines of sight
Disclosed is a method for determining a positional pattern of an irradiation unit for irradiating a patient with treatment radiation. Optimal order data describing an order of the irradiation unit positions for which the statistical value is optimal is determined. The optimal order data is determined based on irradiation unit position data describing irradiation unit positions of the irradiation unit for which the imaging device has a free viewing direction onto the position of the patient, position orders data describing all possible orders of the irradiation unit positions for which the imaging device has a free viewing direction onto the position of the patient, and intersection angle data describing a statistical quantity of the intersection angles between free viewing directions of the imaging unit for irradiation unit positions which are immediately subsequent in the order described by the position orders data. |
| US10780296B2 |
Transcranial laser therapy for treatment of acute ischemic stroke
An apparatus and method of use for a comprehensive transcranial low-level light therapy for use with ischemic brain tissue using a multitude of polychromatic Light Emitting Diodes (LEDs) embedded into a flexible head covering that stretches securely around the patient's cranium to bath the entire cranium cavity in a variable frequency, variable power density light spectrum, maximizing all beneficial effects to the cellular tissues whether or not they are specifically deprived of blood from the ischemic stroke event. The bulbs covering the n-p junction of the semiconductor LEDs directly contact the patient's cranial skin to maximize the depth of penetration of the wavelengths into the brain's cortex cells. By using many individual point-source LEDs emitting all around the cranium, greater therapeutic benefit can be achieved as more of the cortex tissues are irradiated. |
| US10780294B2 |
System and method for photo-dynamic procedure
A problem of incomplete inhibition of harmful cells/bacteria and short duration of time, after the photodynamic treatment, during which such cells may re-grow, is solved by exposing the target bacteria with a multi-component photosensitizer material formed by adding a predetermined potentiating chemical to a conventional single-component photosensitizer at the target, prior to irradiating the target with light. The multi-component photosensitizer is effectuated by forming a mix of the two chemical compositions or by sequential exposure of the bacteria to a single-component photosensitizer and the potentiating chemical of choice. |
| US10780293B2 |
Wearable light emitting apparatus for eyebrow growth
A wearable light emitting apparatus for eyebrow growth is provided. The wearable light emitting apparatus for eyebrow growth comprises a main body and at least one light emitting assembly. The main body is to be wore on an user's head. The at least one light emitting assembly is located on the main body for projecting at least an eyebrow-shaped light beam to an eyebrow growing area of the head when the main body is wore on the user's head. |
| US10780287B2 |
Retrofit to protect implanted devices (e.g., pacemakers) from unauthorized manipulation
An implantable device that (a) has an analog input configured to detect analog electrical signals and (b) is configured to accept RF commands can be retrofitted to prevent unauthorized access by modifying the software of the implantable device to (1) accept control commands that arrive via the analog input and (2) ignore control commands that arrive via the RF transceiver. Ultrasound communications can then be detected and inductively coupled onto a lead that is connected to the analog input. In some embodiments, the modified implantable device can only be controlled via ultrasound signals at all times to improve security. In other embodiments, the modified implantable device can only be controlled via non-ultrasound signals (e.g., RF signals) for short periods of time after the system has been unlocked in response to receipt of a specific ultrasound signal. |
| US10780286B2 |
System and method for transcranial current loop brain stimulation
A method and device is described, which provides electrical stimulation to the brain of a person, where the device comprises an external portion and at least one implantable portion. The external portion provides the energy source for stimulation to the implantable portions. The implantable portions provide at least two conductive paths through the skull and use the skull's high impedance to generate a current loop with the focus of stimulation lying in the current path. |
| US10780277B2 |
Methods of neuromodulation using infraslow stimulation
Methods are provided to treat a neurological disorder in a patient by adjusting connectivity between network nodes in a brain of patient using electrical stimulation. Electrical stimulation including a carrier wave component is employed to adjust connectivity using infraslow frequencies of less than 1 Hz. |
| US10780275B2 |
Implantable neuro-stimulation device
An implantable electrical stimulation device includes an electrically conductive electrode structure configured for coupling with a pulse generator device and transmitting an electrical signal configured to generate a desirable electric field around a target tissue. The electrode structure includes a porous substrate constructed of a bio-compatible and bio-survivable material having a structure that mimics extracellular matrix embedding. The porous substrate supports an electrically conductive electrode element. The implantable device may further include a pulse generator also embedded, enmeshed, and supported within the porous substrate. |
| US10780274B2 |
Systems and methods for delivering spinal cord stimulation therapy
This document discusses, among other things, systems and methods to provide a paresthesia therapy to a patient using an implantable neuromodulation system, wherein providing the paresthesia therapy may include delivering to the patient an electrical waveform having a duration and a distribution of frequencies in the range of 0.001 kHz to 20 kHz, wherein the distribution of frequencies includes a first frequency group of one or more frequencies and a second frequency group of one or more frequencies, and wherein the patient continuously experiences paresthesia throughout the duration of the electrical waveform. |
| US10780270B2 |
System and method to percutaneously block painful sensations
The exemplified systems and methods facilitate a nerve conduction block at a target nerve using electrical stimulation applied from one or more electrodes located on a percutaneous lead that are placed in parallel, or substantially in parallel, and without direct contact, to a long axis of the peripheral nerve over an overlapping nerve region of greater than about 3 millimeters. The exemplified system and method can be further configured to block nerve condition without eliciting onset activity and co-excitation of non-targeted structures. The exemplified method and system can be performed using conventional percutaneous leads, though an improved percutaneous lead design is disclosed herein. In an aspect, an introducer is disclosed that facilitates accurate and consistent insertion of the percutaneous lead to the specified or intended position relative to the target nerve. In another aspect, a treatment kit comprising the various system components to treat pain is disclosed. |
| US10780260B2 |
Sterile connection luer access device
A luer access device (LAD) and a method of attaching the same are provided to create a sterile fluid-flow path. The LAD includes a female luer connector that has an internal female split septum disposed at a proximal end thereof and is coupled to an internal surface of the LAD. A male luer connector is coupled to an external surface of the female split septum. Additionally, a male split septum is disposed within a male luer tip and seals an opening of a distal end of the male luer connector. At least one aperture is disposed through a sidewall of the distal end of the male luer connector. An internal cannula is exposed out of the female luer connector to open the female split septum upon engagement with the male luer connector. |
| US10780256B2 |
System for integrating an antibacterial-element receptacle into an autoinjector cap
A system for integrating an antibacterial-element receptacle into an autoinjector cap facilitates the pre-injection treatment, the post-injection treatment, and prevents the accidental delivery of the injection. The system includes a cap assembly, an autoinjector body, and an antiseptic-soaked dressing. The cap assembly encloses the needle of the autoinjector and prevents the accidental trigger of the injection mechanism. The autoinjector body refers to the body of any conventional autoinjector. The antiseptic-soaked dressing is applied to the patient's skin prior to the delivery of the injection to disinfect and sterilize the injection area. The antiseptic-soaked dressing is housed in the cap assembly, between a receptacle and a removable cover. The removable cover is releasably mounted to the receptacle to allow access to the antiseptic-soaked dressing. |
| US10780255B2 |
Inflatable medical devices
Inflatable medical devices and methods for making and using the same are disclosed. The inflatable medical devices can be medical balloons. The balloons can be configured to have a through-lumen or no through-lumen and a wide variety of geometries. The device can have a high-strength, non-compliant, fiber-reinforced, multi-layered wall. The inflatable medical device can be used for angioplasty, kyphoplasty, percutaneous aortic valve replacement, or other procedures described herein. |
| US10780254B2 |
Non-compliant medical balloon having braided or knitted reinforcement
A non-compliant medical balloon comprises a base balloon including a pair of spaced-apart, generally conical end sections and a generally cylindrical center section connected therebetween. A braided fabric sleeve surrounds at least a portion of the base balloon, wherein the sleeve is formed of at least three substantially inelastic fibers intertwined in such a way that no two of the three fibers are twisted exclusively around one another. The sleeve is permanently affixed to the outer surface of the base balloon so as to prevent excessive expansion of the base balloon when the base balloon is internally pressurized. |
| US10780248B2 |
Radial and trans-endocardial delivery catheter
A needle-injection catheter includes a catheter body having a distal end, a proximal end, a stiff proximal portion, a flexible distal portion, and a delivery lumen extending therethrough. In a first embodiment, a straight injection needle extends coaxially from a distal tip of the flexible portion of the catheter body, and a plurality of penetration limiting elements positioned circumferentially about a base of the straight injection needle and configured to fold radially inwardly against a shaft of the needle when constrained in a tubular lumen and to extend radially outwardly when unconstrained. In a second embodiment, a helical needle extends from the distal tip of the flexible portion of the catheter body. The helical needle has at least one helical delivery lumen connected to receive an injectable substance from the delivery lumen of the catheter body. |
| US10780246B2 |
Vascular microcatheter
There is provided a microcatheter with a tapering wall thickness shaft having varying stiffness/flexibility along its length from proximal end near the medical practitioner to the distal end near the target site in the patient, such as with at least three segments. The shaft is prepared of a thermoplastic material having varying composition along its length. The distal end may be shaped according to the required use just prior to the medical procedure. The microcatheter is particularly adapted for the delivery of microspheric compositions for treatment of tumors or fibroids by embolization of peripheral blood vessels of the tumor or fibroid. |
| US10780239B2 |
Method and system for controlling patient sedation and spontaneous breathing intensity
A system for controlling patient sedation and spontaneous breathing intensity includes a ventilator system that delivers ventilation to the patient. The system further includes a spontaneous breathing control module configured to determine a first spontaneous breathing intensity at a first sedative status of the patient, and a second spontaneous breathing intensity at a second sedative status of the patient. A sedation/breathing relationship is then defined between spontaneous breathing intensity and sedative status for the patient based on the first and second sedative statuses and the first and second spontaneous breathing intensities. The spontaneous breathing control module then receives a desired spontaneous breathing intensity for the patient and determines a desired sedative status that achieves that desired spontaneous breathing intensity based on the sedation/breathing relationship. |
| US10780232B2 |
System for cap removal
The present disclosure relates to a pen injecting device for delivering a liquid medicament comprising a pen body and a needle is received in a first end of the pen body. The pen injecting device further comprises an inner needle shield, removeably located over the needle to enclose the needle, and an outer needle shield, removeably located over the inner needle shield to enclose the inner needle shield. The pen injecting device also comprises a pen cap removeably attached to the first end of the pen body so as to enclose the outer needle shield. The pen cap comprises an arm depending from an inside surface of the cap and extending away from the first end of the pen body toward the inner and outer needle shields, the arm having a sharp end so that, as the cap is removed from the body, the sharp end of the arm grips the inner or outer needle shield to retain it in the cap and expose the needle. |
| US10780227B2 |
Pre-filled syringe or autoinjector
The invention provides a syringe for dispensing a drug (1), comprising: a rigid syringe body, —a first container (2), in contact with and enclosing the drug; and a second container (3), enclosing the first container, the second container being less gas permeable than the first container, wherein the second container partially or fully forms the rigid syringe body or is held within the rigid syringe body. The invention preserves the drug but allows the drug to be easily accessed without the need for a user to remove a gas barrier structure as a separate action in addition to the other actions needed to deliver the drug. |
| US10780224B2 |
Medical device data integration apparatus and methods
Methods, systems, and apparatuses for integrating medical device data are disclosed. In an example embodiment, an integration engine receives infusion therapy progress data from an infusion pump and renal failure therapy progress data from a renal failure therapy machine. The integration engine determines a plurality of different types of infusion parameters, determines a plurality of different types of renal failure therapy parameters, and causes a combination user interface to display the plurality of infusion parameters, the plurality of renal failure therapy parameters, and mathematical operations for selection by an operator. The integration engine enables the operator to create derivative data by receiving a selection of an infusion parameter, a renal failure therapy parameter, and a mathematical operation. The integration engine then causes the combination user interface to display the derivative data in conjunction with the infusion therapy progress data and the renal failure therapy progress data. |
| US10780220B2 |
Patch-sized fluid delivery systems and methods
A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device. |
| US10780216B2 |
Implantable medical device for minimally-invasive insertion
In one aspect, containment devices are provided that include a microchip element having one or more containment reservoirs that are configured to be electrically activated to open; an electronic printed circuit board (PCB) or a silicon substrate positioned adjacent to the microchip element; one or more electronic components associated with the microchip element or the PCB/silicon substrate; and a first inductive coupling device associated with the microchip element or the PCB/silicon substrate, wherein the first inductive coupling device is in operable communication with the one or more electronic components. In another aspect, implantable drug delivery devices are provided that include a body housing at least one drug payload for actively controlled release, wherein the ratio of the volume of the at least one drug payload to the total volume of the implantable drug delivery device is from about 75 μL/cc to about 150 μL/cc. |
| US10780215B2 |
Device and method for setting therapeutic parameters for an infusion device
Embodiments are directed to infusion devices, systems, and methods to detect a capacity of a collapsible fluid reservoir of an infusion cartridge and/or a volume of a fluid disposed in the collapsible fluid reservoir or some other parameters of the infusion cartridge, and setting corresponding therapeutic parameters of an infusion device. Embodiments may include, obtaining data on the volume of fluid in the collapsible fluid reservoir, analyzing the obtained data to determine the setting of therapeutic parameters, and setting one or more therapeutic parameters of an infusion device. |
| US10780214B1 |
Implantable medical delivery device securing excess catheter tubing
A medication delivery device—preferably designed and configured to be implantable for use inside of a human body—secures excess tubing of a catheter to a pump housing. The tubing is received and retained in channels, whereby an excess extent of the catheter that is unneeded can be safely stored in an out-of-the-way position. The channels are defined in and integrally formed with the pump housing. Alternatively, the channels are defined in a catheter retention member that clips onto other otherwise attaches to the pump housing. In the alternative design, the catheter retention member may be provided separately from or provided with the pump and catheter. |
| US10780211B2 |
Apparatus for carrying out an apheresis treatment
The present invention relates to an apparatus for carrying out an apheresis treatment, wherein the apparatus has an extracorporeal circuit in which a regenerable single adsorber is located for separating substances from blood or for separating substances from plasma acquired by means of a plasma separator, wherein a line is provided for conducting the blood or the plasma which extends to the adsorber and via which blood or plasma is applied to the adsorber, wherein a reservoir is provided for receiving blood or plasma and is arranged upstream of the adsorber in the line or is in communication with the line upstream of the adsorber; and in that a controller or switching means is provided which is configured such that the reservoir is filled with blood or plasma and the application of blood or plasma to the adsorber is suppressed when the regeneration of the adsorber is carried out. |
| US10780210B2 |
Enclosure for a portable hemodialysis system
An enclosure for containing a portable hemodialysis unit includes a housing suitable to support components for performing hemodialysis including a dialyzer, one or more pumps to circulate blood through the dialyzer, a source of dialysate, and one or more pumps to circulate the dialysate through the dialyzer. The housing may have a front panel at which blood circuit connections and dialysate fluidic connections are located, e.g., blood line connections for patient blood access, connections for a reagent supply, dialyzer connections for both blood flow and dialysate, etc. The enclosure may also include a pair of vertical, side-by-side doors hingedly mounted to the housing. With the doors in the closed position, access to the patient access and dialysate fluidic connections may be blocked, and the doors may allow for the retention of heat in the housing suitable for disinfection during a disinfection cycle. |
| US10780208B2 |
Blood pump
A blood pump comprises a pump casing having a blood flow inlet and a blood flow outlet, and an impeller arranged in said pump casing and rotatably supported in the pump casing by a bearing so as to be rotatable about an axis of rotation. The impeller has blades for conveying blood from the blood flow inlet to the blood flow outlet. The bearing comprises at least one stationary bearing portion coupled to the pump casing and having a stationary bearing surface that faces radially outwards. The bearing further comprises a rotating bearing surface interacting with the stationary bearing surface to form the bearing, wherein the rotating bearing surface faces radially inwards and is formed on an exposed radially inner edge of the blades. The blades are designed to draw blood deposit on the stationary bearing surface in a radially outward direction. |
| US10780204B2 |
Biological fluid-treating filter and filter device
Provided is a biological fluid-treating filter for treating a biological fluid containing erythrocytes, which has a matrix and a polymer retained by the matrix, the polymer having a zwitterion-containing functional group and a basic nitrogen-containing functional group. By using the filter in which the polymer has the zwitterion-containing functional group and the basic nitrogen-containing functional group, it is possible to treat the biological fluid containing erythrocytes without adversely affecting the erythrocytes. |
| US10780201B2 |
Control apparatus and related methods for wound therapy delivery
In various aspects, the wound therapy apparatus disclosed herein includes a wound interface that defines an enclosed space over a wound bed that is fluid tight when secured to a skin surface around the wound bed. The wound therapy apparatus includes a control group that cooperates with the wound interface to regulate input of input fluid comprising a gas having an O2 concentration greater than atmospheric air into the enclosed space and to regulate the withdrawal of output fluid from the enclosed space in order to vary an actual pressure pa within the enclosed space generally between a minimum pressure pmin and a maximum pressure pmax, the minimum pressure pmin being less than ambient pressure pamb, in various aspects. The input of the gas having an O2 concentration greater than atmospheric air is sequential with withdrawal of the gas having an O2 concentration greater than atmospheric air, in various aspects. Related methods of use of the wound therapy apparatus are disclosed herein. This Abstract is presented to meet requirements of 37 C.F.R. § 1.72(b) only. This Abstract is not intended to identify key elements of the methods of use and related apparatus disclosed herein or to delineate the scope thereof. |
| US10780199B2 |
Methods of applying a hydrophilic coating to a substrate, and substrates having a hydrophilic coating
This invention relates to methods of applying to a substrate a hydrophilic coating that becomes lubricious when activated with water or water vapor, and to substrates having such a hydrophilic coating. |
| US10780197B1 |
Malleable, cryopreserved osteogenic compositions with viable cells
A bone graft composition comprising a viable, osteogenic cellular material combined with a viscous cryoprotectant that includes a penetrating cryoprotective agent and a non-penetrating cryoprotective agent. The viscosity of the cryoprotectant is such that the composition is malleable, cohesive and capable of being formed into desired shapes. |
| US10780195B2 |
Controllably degradable compositions and methods
Methods, compositions, kits, and drug delivery devices are provided for treating, adhering, or sealing biological tissues. The methods include combining a first solution that includes an oligomer/polymer component and a second solution that includes a dendrimer component, and at least one of the oligomer/polymer component and dendrimer component includes at least one substituent that is capable of photoreversible dimerization. The reversible dimerization of the substituent may allow for the reversible dimerization and/or polymerization of one or more components. The substituent that is capable of photoreversible dimerization may be active by the application of light, such as UV light. |
| US10780190B2 |
Method and apparatus for disinfection
A process and apparatus for disinfection of spaces using a disinfecting liquid droplet spray atomization are described, in which an electric fan 107 is used to dispense the atomization from an atomization chamber 104 via venture outlets 106 into the space to be disinfected. The operation of the electric fan 107 is modulated in a cycle having a first phase in which the fan is operated at full speed and a second phase at which the fan is operated at a randomly selected speed to vary the rate of dispensing into the space in order to improve the dispersal of the atomized droplets in the space and hence the efficacy of disinfection. |
| US10780188B2 |
Ultraviolet irradiation device
An ultraviolet irradiation device having higher processability and interfacial adhesiveness, and allowing downsizing is provided. The ultraviolet irradiation device includes an enclosure configured to include a hollow portion being formed inside and being capable of introducing an irradiation object, an outer periphery of the enclosure being covered by a covering portion, and a light source configured to be arranged in an area not covered by the covering portion of the enclosure and project light toward the hollow portion. The covering portion is formed of thermoplastic resin fiber. Processability and interfacial adhesiveness can be improved by forming the covering portion with thermoplastic resin fiber. Consequently, a structure advantageous for downsizing of the ultraviolet irradiation device is provided. |
| US10780187B2 |
Apparatus and method for sterilizing internal channel surface of endoscope
Provided are an apparatus and method for sterilizing an internal channel surface of an endoscope, and more particularly, to an apparatus and method for sterilizing an internal channel surface of an endoscope, in which ultrasonic and infrared rays are irradiated to an internal channel of the endoscope to partially or entirely sterilize and removing a biofilm generated on the internal channel surface of the endoscope during a procedure or diagnosis. |
| US10780186B2 |
System, apparatus, equipment with thermal disinfection and thermal disinfection methods
Water systems, medical equipment, and apparatus for thermal disinfection comprise a control unit which starts the disinfection of a fluid path by controlling a heating unit to heat water and controlling an actuator to enable heated water to flow into the fluid path. The control unit reads the temperature as measured by a temperature sensor during the disinfection and calculates an achieved disinfection dose. The achieved disinfection dose is compared with a set disinfection dose and the disinfection is discontinued if the achieved disinfection dose corresponds to the set disinfection dose. |
| US10780184B2 |
Fluorescent solid lipid nanoparticles composition and preparation thereof
The present invention discloses a solid lipid nanoparticle (SLN) comprising: a) a solid lipid core comprising at least a glyceride and/or at least a fatty acid; b) a mixture of amphiphilic components forming a shell around said core a); c) an alkaline-earth complex with a compound of formula I and/or II: d) at least a fluorescent dye selected from: a cyanine fluorescent dye and/or a polyetherocyclic compound selected from: coumarin, pyrano, quinoline, pyranoquinoline, indole and pyranoindole derivates in acid form or a pharmaceutically acceptable salt thereof. These nanoparticles allow a prolonged blood circulation half-life, show enhanced photostability and improved fluorescence signal. The dye is preserved from degradation and improves the fluorescent quantum yield. |
| US10780183B2 |
Messenger RNA therapy for the treatment of Friedreich's ataxia
The present invention provides methods and compositions of treating Friedreich's ataxia (FRDA) based on administering an mRNA encoding a frataxin protein. |
| US10780181B2 |
Pyrrolobenzodiazepine-antibody conjugates
Conjugates of an antibody that binds to CD19 with PBD dimers. |
| US10780178B2 |
Scaffolded HIV-1 vaccine immunogens
The present invention provides novel scaffolded HIV-1 vaccine immunogens. Some of the scaffolded immunogens contain a soluble gp140 trimer linked to the N-terminus of the nanoparticle subunit and a T-helper epitope that is fused via a short peptide spacer to the C-terminus of the nanoparticle subunit. Some other immunogens of the invention contain a soluble gp140 trimer protein that is linked to a stable nanoparticle via a short peptide spacer that is a T-helper epitope. Some of the scaffolded immunogens contain a gp140 trimer immunogen presented on a nanoparticle platform formed with I3-01 protein, E2p, or variants of protein 1VLW. Also provided in the invention are nucleic acids that encode the various vaccine immunogens described herein, and expression vectors and host cells harboring the nucleic acids. The invention further provides methods of using the scaffolded HIV-1 vaccine immunogens for preventing or treating HIV infections. |
| US10780175B2 |
Polymer systems and their applications in diagnostics and drug delivery
The present invention provides a biodegradable “precision polymer system” (poly system) and methods for preparing pharmaceutically effective “precision polymer nanosystems” (polymer nanosystem) for delivery and/or targeting of drugs or drug like compounds. |
| US10780173B2 |
Natural preservatives and antimicrobial agents, including compositions thereof
Compositions are disclosed herein that comprise a mixture of at least one Albizia extract and a Magnolia extract. In some embodiments, the composition comprises a mixture of at least one Albizia extract enriched for one or more macrocyclic alkaloids and at least one Magnolia extract enrich for one or more lignans. |
| US10780170B2 |
Stevia extract containing selected steviol glycosides as flavor, salty and sweetness profile modifier
Stevia extracts with selected major steviol glycosides (Reb A, stevioside, Reb D, Reb C) and minor steviol glycosides and glycosylated diterpene derivative plant molecules, derived from Stevia rebaudiana plant are found to improve the perception of flavor and taste perception, which includes the sweet, savory and salty perception in a wide range of food and beverage applications. |
| US10780166B2 |
Pharmaceutical compositions comprising meloxicam
Disclosed herein are compositions comprising an NSAID such as meloxicam and/or rizatriptan in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These compositions may be orally administered, for example, to improve the bioavailability or pharmacokinetics of the NSAID for the treatment of pain such as migraine, arthritis, and other conditions. Also disclosed herein are methods of treating pain, such as migraine, comprising administering meloxicam and rizatriptan to a human being suffering from pain, such as migraine. For migraine, these methods may be particularly useful when the meloxicam and rizatriptan are administered while the human being is suffering from an acute attack of migraine pain or migraine aura. In some embodiments, the combination of meloxicam and rizatriptan may be administered in a manner that results in a Tmax of meloxicam of 3 hours or less. |
| US10780165B2 |
Pharmaceutical compositions comprising meloxicam
Disclosed herein are compositions comprising an NSAID such as meloxicam and/or rizatriptan in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These compositions may be orally administered, for example, to improve the bioavailability or pharmacokinetics of the NSAID for the treatment of pain such as migraine, arthritis, and other conditions. Also disclosed herein are methods of treating pain, such as migraine, comprising administering meloxicam and rizatriptan to a human being suffering from pain, such as migraine. For migraine, these methods may be particularly useful when the meloxicam and rizatriptan are administered while the human being is suffering from an acute attack of migraine pain or migraine aura. In some embodiments, the combination of meloxicam and rizatriptan may be administered in a manner that results in a Tmax of meloxicam of 3 hours or less. |
| US10780164B2 |
Multifunctional nanoparticle compositions and uses thereof
Disclosed herein are multifunctional nanoparticle compositions. The compositions can be useful for the treatment of cancer by enhancing the anti-tumor effectiveness of radiation directed to a tissue, cell or a tumor and the methods of use thereof. The multifunctional nanoparticle composition comprises a metal oxide nanoparticle core; a functional coating on the surface of the metal oxide nanoparticle core; and a matrix carrier in which the coated nanoparticle is embedded. |
| US10780161B2 |
Vector co-expressing vaccine and costimulatory molecules
Compositions and methods for co-expressing a secretable vaccine protein (such as gp96-Ig) and T-cell co-stimulatory molecules from a single vector, among others, are provided herein. Materials and methods for using gp96-Ig vaccination and T-cell co-stimulation to treat a clinical condition (e.g., cancer) in a subject also are provided. |
| US10780160B2 |
Process for preparing pneumococcal polysaccharide-protein conjugates
An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate contains a capsular polysaccharide prepared from a different serotype of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F) conjugated to a carrier protein. The immunogenic composition, formulated as a vaccine, increases coverage against pneumococcal disease in infants and young children globally, and provides coverage for serotypes 6A and 19A that is not dependent on the limitations of serogroup cross-protection. |
| US10780159B2 |
Chimeric peptides against HTLV-1
A method of immunizing against HTLV-1 is disclosed. The method may include preparing a DNA sequence corresponding to a chimeric peptide which may have immunogenic epitopes of HTLV-1. These epitopes can include a Tax epitope, a gp21 epitope, a gp46 epitope, and/or a gag epitope. The method also includes production of the chimeric peptide using the DNA sequence and purifying the produced chimeric peptide. The purified chimeric peptide can be employed for immunization against HTLV-1. |
| US10780157B2 |
Multi-CBV vaccine for preventing or treating type I diabetes
The invention is directed to a vaccine comprising: i) coxsackie B virus CBV1 and CBV2, and ii) at least one coxsackie B virus selected from CBV3, CBV4, CBV5 and CBV6. The CBVs are present in the vaccine in inactivated form, in the form of a component of the virus or as an antibody against the virus. The vaccine is effective in preventing and treating type 1 diabetes. So is an anti-coxsackie B virus composition provided. |
| US10780156B2 |
Treatment of pigs with PCV2 antigen
The present invention relates to a method for the treatment or prophylaxis of a PCV2 infection or for reduction of clinical symptoms caused by or associated with a PCV2 infection in animals a) having anti-PCV2 antibodies and/or b) being young piglets of 1 to 22 days of age, comprising the step of administering an effective amount of a PCV2 antigen to that animal in need of such treatment. Preferably, those animals are pigs or young piglets. |
| US10780151B2 |
Composition and therapeutic anti-tumour vaccine
The invention relates to a composition which induces, in a host, a cytotoxic cell response directed against cells expressing an antigen, in particular tumour cells, and which comprises red blood cells containing said antigen. These red blood cells may be in the form of an immune complex with an immunoglobulin, in particular IgG, which recognizes an epitope at the surface of the red blood cells, and/or be heat-treated or chemically treated so as to promote phagocytosis of said red blood cells by dendritic cells. As a variant, the red blood cells may be xenogenic red blood cells. The invention also relates to a therapeutic especially anti-tumour vaccine containing such a composition. |
| US10780150B2 |
Glycosylated oligonucleotides that mimic the HIV-1 epitope of neutralizing monoclonal antibody 2G12
Disclosed are oligonucleotides that binds specifically to HIV neutralizing monoclonal antibody 2G12 with a K4 value lower than 20 nM, the oligonucleotide comprising a predicted structure, at 37° C., having exactly one stem-loop whereby the loop comprises the nucleotide sequence of AACCNACGGANAAA (SEQ ID NO: 1), where N is a modified nucleoside base, and the stem includes at least 3 nucleotide base-pairs and one of the nucleotides in the stem includes a modified nucleoside base, wherein the modified nucleoside base has the structure -B-L-A where A is a branched-chain Man9 oligosaccharide, L is a linker molecule, and B is independently a pyrimidine or pyridine base linked to the sugar-phosphate backbone of the oligonucleotide. Immunogenic conjugates that include the oligonucleotide, and pharmaceutical compositions that include the oligonucleotide or the immunogenic conjugate are also disclosed. Various method of using the oligonucleotides, immunogenic conjugates, and pharmaceutical compositions are also disclosed. |
| US10780148B2 |
Hemoglobin compositions
The invention provides compositions containing hemoglobin, particularly PEGylated hemoglobin. The PEGylated hemoglobin molecule is capable of transferring oxygen or carbon monoxide bound thereto to a tissue with which it is in proximity. Exemplary PEGylated hemoglobin formulations of the invention are virally inactivated. Various compositions of the invention include deoxygenated hemoglobin, which may be conjugated with one or more water-soluble polymer. PEGylated hemoglobin includes those species in which the iron atom of the hemoglobin molecule is not bound to oxygen or any other species, and hemoglobin molecules in which a species other than oxygen, e.g., carbon monoxide, is bound to the iron atom. The compositions of the invention are formulated as hypo-, iso- or hypertonic solutions of the PEGylated hemoglobin. The compositions are of use to treat and/or ameliorate disease, injury and insult by providing for the oxygenation of tissues and/organs. |
| US10780141B2 |
Herbal combinations for treating eczema
A shampoo, conditioner, cream, ointment or other topical treatment includes an active herbal combination of Sheng Di Huang, Da Huang and Jin Yin Hua for treating eczema, and/or another skin or scalp disorder. |
| US10780138B2 |
Extract of andrographis paniculata for cognitive enhancement
The present invention provides an aqueous extract of Andrographis paniculata leaves containing as main components andrographolide, neoandrographolide and 14-deoxy-11,12-didehydroandrographolide. The Invention also provides a method of production of said extract, comprising the steps of drying the leaves of Andrographis paniculata, and extracting them with water at a temperature of at least 50° C. The aqueous extract of Andrographis paniculata Leaves Is suitable for use as cognition enhancing agent having antineuroinflammatory and antioxidative effects. |
| US10780136B2 |
Reduction of milk glycans and their degradation products in the neonate gut
Methods of reducing milk glycans, and thus enteric pathogens that use such glycans as carbon sources, in the gut of nursing mammals. |
| US10780132B2 |
Use of adipose tissue-derived stromal stem cells in treating fistula
Provided herein are novel methods and compositions utilizing adipose tissue-derived stromal stem cells for treating fistulae. |
| US10780131B2 |
Ameliorating nervous systems disorders
The present disclosure provides methods for the treatment of a mammal having a neurological condition, disease, or injury. The methods involve increasing the number of functional GABAergic interneurons at or near the site of the neurological disease, injury, or condition. |
| US10780129B2 |
Use of mesenchymal stem cells in treating osteoarthritis
The present invention relates to a use of hypoxia-cultured mesenchymal stem cells (MSCs) for manufacture of a cell graft for treating a musculoskeletal disorder, particularly osteoarthritis. |
| US10780127B2 |
Method for producing fermented milk having high angiotensin converting enzyme inhibitory activity and method for producing physiologically active peptide
The present invention provides fermented milk having a high angiotensin converting enzyme inhibition activity, a high hypotensive activity and/or a high stroke-preventing activity. The present invention also provides a method for producing fermented milk having a high angiotensin converting enzyme inhibition activity, a high hypotensive activity and/or a high stroke-preventing activity and a method for producing Tyr-Pro, each of which is characterized by comprising fermenting milk with a mushroom. |
| US10780124B2 |
Peptides and combination of peptides of non-canonical origin for use in immunotherapy against different types of cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules. |
| US10780122B2 |
Peptides and combination of peptides of non-canonical origin for use in immunotherapy against different types of cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules. |
| US10780120B2 |
Prostate-specific membrane antigen cars and methods of use thereof
The present disclosure provides modified immune cells (e.g., modified T cells) comprising a chimeric antigen receptor (CAR) having affinity for a prostate-specific membrane antigen (PSMA) (e.g., human PSMA). The present disclosure provides modified immune cells (e.g., modified T cells) comprising a CAR having affinity for PSMA and a dominant negative receptor and/or a switch receptor. The present disclosure provides modified immune cells (e.g., modified T cells) comprising a CAR having affinity for PSMA and a dominant negative receptor and/or a switch receptor, wherein the modified cell is capable of expressing and secreting a bispecific antibody. |
| US10780118B2 |
Method and compositions for cellular immunotherapy
The present invention provides nucleic acids, vectors, host cells, methods and compositions to confer and/or augment immune responses mediated by cellular immunotherapy, such as by adoptively transferring CD8+ central memory T cells or combinations of central memory T cells with CD4+ T cells that are genetically modified to express a chimeric receptor. In embodiments the genetically modified host cell comprises a nucleic acid comprising a polynucleotide coding for a ligand binding domain, a polynucleotide comprising a customized spacer region, a polynucleotide comprising a transmembrane domain, and a polynucleotide comprising an intracellular signaling domain. It has been surprisingly found that the length of the spacer region can affects the ability of chimeric receptor modified T cells to recognize target cells in vitro and affects in vivo efficacy of the chimeric receptor modified T cells. Pharmaceutical formulations produced by the method, and methods of using the same, are also described. |
| US10780116B2 |
Use of fullerene structure in preparation of medicaments for treating Parkinson's disease
An application of a fullerene structure in the preparation of medications for treating Parkinson's disease. The fullerene structure comprises at least one of the following active ingredient groups: a fullerene, a metallofullerene, and a composition of the fullerene and the metallofullerene; an oil-soluble fullerene, an oil-soluble metallofullerene, and a composition of the oil-soluble fullerene and the oil-soluble metallofullerene; a water-soluble fullerene, a water-soluble metallofullerene, and a composition of the water-soluble fullerene and the water-soluble metallofullerene; the medicinal esters of the nine elements, or the medicinal salts of the nine elements. |
| US10780115B2 |
Preparation of antimicrobial agent based on ZnO/GQD-PEI composites
Preparation of high-performance antimicrobial agent based on ZnO/GODs-PEI composites. Nano ZnO is regarded as the effective antibacterial agents because of its distinctive photocatalytic properties. However, the fast recombination of photo-generated electrons and holes on the surface of ZnO seriously affects antibacterial activities. Therefore, numerous methods such as controlling the size and morphology of ZnO, doping metal and nonmetal ions, coupling semiconductor, constructing heterojunction and surface modification have been used to increase the activity of ZnO. The application aims to synthesize a stable low-dimensional ZnO/GQD aqueous with excellent dispersity and enhanced absorption to further improve its antibacterial activities. Hence, amphiphilic polyethylenimine-functionalized graphene quantum dots (GQD-PEI) was prepared firstly, which was then used to transfer ZnO NPs to water to obtain water-soluble ZnO/GODs-PEI composites. |
| US10780112B2 |
Colonoscopy-preparation
The invention provides a colon cleansing solution comprising: a) 300 to 2000 mmol per litre ascorbate anion provided by ascorbic acid, one or more salts of ascorbic acid, or a mixture thereof; and b) 10 to 200 g per litre polyethylene glycol. The invention also provides methods and kits associated with, or making use of the solutions. The invention also provides a method of cleansing the colon of a subject comprising: —administering to the subject an effect amount of a first cleansing solution; and then after a time interval —administering to the subject an effective amount of a second cleansing solution, wherein the two cleansing solutions are as described in the specification. |
| US10780109B1 |
Method for treating a tooth using selenite
A method of treating a tooth of a user. Initially, a tooth is cut to have an opening of at least 1 to 4 mm in the direction along an occlusal surface of the tooth, or a tooth already cut to have such an opening is located. Following ensuring that the opening is dry, powdered selenite is inserted into the opening. Subsequently, the powdered selenite is covered with a dental composite, thereby sealing the powdered selenite in the tooth. |
| US10780107B2 |
Agent for inducing cell death, agent for suppressing cell proliferation, and pharmaceutical composition used for treatment of disease resulting from abnormal cell proliferation
This invention provides an agent and a composition that induces cancer cell death and suppresses cancer cell proliferation. The agent and the composition comprises, as an active ingredient, a drug for suppressing GST-π and MRPL17 or comprises, as active ingredients, a drug for suppressing GST-π and a drug for suppressing MRPL17. |
| US10780106B2 |
Method for treating NASH accompanied by fibrosis using Cl-IB-MECA
Provided is an A3AR ligand for reducing ectopic fat accumulation, particularly in fatty liver. Further provided is the use of A3AR ligand for the preparation of a pharmaceutical composition for reducing such fat accumulation, method of treating a condition associates with fat accumulation making use of the ligand and kits including pharmaceutical compositions including the ligand, and instructions for use of same, for treating a condition associated with ectopic fat accumulation. Further provided is the use of an A3AR agonist, such as 2-Chloro-N6-(3-iodobenzyl)-adenosine-5′-N-methyluronamide (Cl-IB-MECA, CF102) for treating fatty liver, specifically, non-alcoholic fatty liver disease (NAFLD). |
| US10780104B2 |
Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof
This application relates to combination therapies including triciribine compounds and epidermal growth factor receptor inhibitor compounds, particularly erlotinib-like compounds and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation. |
| US10780103B2 |
Synthetic composition and method for modulating emotion and mood disorders
A synthetic composition for use in treating or improving one or more emotion and/or mood disorders in a patient, characterised in that the composition contains an effective amount of one or more neutral human milk oligosaccharides, is disclosed. |
| US10780096B2 |
Pyrrolobenzodiazepine-antibody conjugates
The present disclosure relates to the use of antibody-drug conjugates (ADCs) comprising pyrrolobenzodiazepine (PBD) dimers and anti-CD25 antibodies for use in treating disorders characterized by the presence of CD25+ve cells. |
| US10780093B2 |
Methods of treating brain tumors using combination therapy
Provided are methods of treating a brain tumor in a patient in need thereof comprising administering to the patient a compound described herein and radiation therapy and/or one or more additional therapeutic agents. |
| US10780092B2 |
Fused pyrazine derivatives useful as soluble guanylate cyclase stimulators
The invention provides certain fused pyrazine compounds of the Formula (I) or a pharmaceutically acceptable salts thereof, wherein X, Y, R1, R3, R4a, R5a, R5b, R6, and the subscript t are as described herein. The compounds or their pharmaceutically acceptable salts can modulate the body's production of cyclic guanosine monophosphate (“cGMP”), and are generally suitable for the therapy and prophylaxis of diseases or disorders which are associated with a disturbed cGMP balance. The invention also provides pharmaceutical compositions which comprise compounds of Formula (I) or pharmaceutically acceptable salts thereof. The invention also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of the abovementioned diseases and disorders and for preparing pharmaceuticals for this purpose. |
| US10780089B2 |
Pyrimidine derivatives for the treatment of viral infections
This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV. |
| US10780088B2 |
Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP)
A compound having the structure set forth in Formula (I) and Formula (II): wherein the substituents Y, Z, A, B, R1, R2, R3, R4 and R5 are as defined herein. Provided herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity. |
| US10780086B2 |
Method of inhibiting constitutively active phosphorylated FLT3 kinase
The present invention includes a method of inhibiting or reducing deregulated FLT3 tyrosine kinase activity or FLT3 tyrosine kinase expression in a subject with a proliferative disease by administering to the subject having or suspected to have the proliferative disease, a therapeutically or prophylactically effective amount of the compound of Formula I: or pharmaceutically acceptable salt thereof. |
| US10780084B2 |
Antibody-recruiting molecules for the treatment of cancer
The present invention relates to chimeric (including bifunctional) compounds, compositions comprising those compounds and methods of treating cancer in a patient or subject, especially including metastatic and other cancers where cancer cells exhibit overexpression (heightened expression) of cell surface urokinase-type plasminogen activator receptor (urokinase receptor) compared to normal (non-cancerous) cells. The compounds bind to the urokinase-type plasminogen activator receptor (uPAR) on the surface of a cancer cell, including a metastatic cancer cell, and consequently recruit native antibodies of the patient or subject where the antibodies can selectively degrade and/or deactivate targeted cancer cells through antibody-dependent cellular phagocytosis and antibody-dependent cellular cytotoxicity (ADCC) and/or complement dependent cytotoxicity (CDC) against a large number and variety of cancers, thus providing cancer cell death and an inhibition of growth, elaboration and/or metastasis of the cancer, including remission and cure of the patient's cancer. |
| US10780080B2 |
Benzamide and active compound compositions and methods of use
The present invention describes compositions, including pharmaceutical compositions, comprising an agent that binds members of the TNFRSF and a benzamide compound and methods for use thereof, for example in the treatment of cancer. In some implementations, the methods for use include methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer. |
| US10780071B2 |
Compositions, methods and/or devices for prevention and/or treatment of dry eye disorders
The present disclosure relates to compositions, methods and devices for treating, reducing or preventing one or more eye disorders, particularly dry eye disorders, in a subject by administering an amount of one or more fatty acids and/or fatty acid esters therapeutically effective to inhibit lipase activity while permitting bacterial growth or without substantially altering the dynamic microbial community of the eye. Typically, the fatty acids and/or fatty acid esters are C8 to C16 fatty acids and/or fatty acid esters. |
| US10780068B2 |
Methods and compositions for improving eye health
Provided herein are methods of treating glaucoma in a patient, comprising: obtaining a biological sample from the patient; testing the biological sample for presence of a mutation in Kir6.2 protein or KCNJ11 gene; and provided that the biological sample tests positive for the presence of a mutation in Kir6.2 protein or KCNJ11 gene, administering to the patient a therapeutically effective amount of a composition comprising tolbutamide or a physiologically equivalent salt or solvate thereof and a pharmaceutically acceptable carrier. Also provided herein are methods of maintaining and/or improving eye health in a subject, comprising: administering to the patient a therapeutically effective amount of a composition comprising tolbutamide or a physiologically equivalent salt or solvate thereof, and a pharmaceutically acceptable carrier. |
| US10780066B2 |
Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic effects
This disclosure relates to methods administering various compounds in conjunction with dextromethorphan to a human being. Dosage forms, drug delivery systems, and methods related to dextromethorphan or dextrorphan and bupropion, hydroxybupropion, erythrohydroxybupropion, threohydroxybupropion, or a metabolite or prodrug of any of these compounds are also disclosed. |
| US10780061B2 |
Composition comprising farnesol and use thereof
A method of increasing PGC-1α gene expression, decreasing PARIS gene expression, or promoting farnesylation of PARIS in a mammalian cell, the method comprising administering an effective amount of farnesol, a pharmaceutically acceptable salt thereof, or a solvate thereof to the cell; and related methods and compositions. |
| US10780059B2 |
Process for producing layered bodies
A layered body comprising: a core region; at least one intermediate layer disposed around the core region; and an outer layer disposed around the at least one intermediate layer, wherein at least one of the at least one intermediate layers comprises a gas, the layered body having at least one dimension, measured across the body and through the core region, of 100 μm or less. |
| US10780057B2 |
Casein-based silica dual drug-loading composite microcapsule and preparation method therefor
This invention presents a method for preparing casein-based silica dual drug-loaded composite microcapsule. Recently, casein has shown good application prospects in the field of medicine due to its good biocompatibility and unique cavity structure. However, research on preparation of casein-based dual drug-loaded microcapsules is still rarely reported. In this invention, dual drug-loaded casein microcapsules is obtained via interfacial polymerization method, where drug-loaded casein can be used as outer shell material in capsule, and silica is served as inner shell in the capsule. In the obtained microcapsule, drugs can not only be loaded in the inner cavity, but also in casein shell. Application of the dual drug-loaded microcapsules in the treatment of diseases is expected to reduce the number of dose to a certain extent and improve the therapeutic effect. |
| US10780055B2 |
Delayed release deferiprone tablets and methods of using the same
The invention is directed to pharmaceutical compositions such as tablets that exhibit delayed release properties when administered as either whole or half tablets. The invention is also directed to delayed release tablets comprising deferiprone for oral administration, for which twice daily administration is bioequivalent to the same daily dose of an immediate release tablet administered thrice daily. The invention is also directed to methods of making and using the same. |
| US10780053B2 |
Microparticles and nanoparticles having negative surface charges
This invention provides methods for producing a polymer particle which contains unusually high negative charges on the surface of the particle. Preferably, the polymer is pharmaceutically acceptable. The negative charges can be conferred by chemical groups such as carboxyl, sulfonate, nitrate, fluorate, chloride, iodide, persulfate, and many others, with carboxyl group being preferred. The invention also provides polymer particle produced by the methods of the invention. |
| US10780050B2 |
Lyophilized compositions comprosing albumin-EGFR paclitaxel nanoparticle complexes
Described herein are compositions of antibodies and carrier proteins and methods of making and using the same, in particular, as a cancer therapeutic. Also described are lyophilized compositions of antibodies and carrier proteins and methods of making and using the same, in particular, as a cancer therapeutic. |
| US10780049B2 |
Lyophilized compositions comprising albumin-rankl or albumin-GD2 paclitaxel nanoparticle complexes
Described herein are compositions of antibodies and carrier proteins and methods of making and using the same, in particular, as a cancer therapeutic. Also described are lyophilized compositions of antibodies and carrier proteins and methods of making and using the same, in particular, as a cancer therapeutic. |
| US10780046B2 |
Pharmaceutical compositions comprising silica microspheres
Topical vaginal compositions are disclosed herein which include silica microspheres and an active ingredient in the amount of 0.001 to 15.0% w/w selected from estradiol, metronidazole, clindamycin, butoconazole, and combinations thereof. The topical compositions provide sustained release of the active ingredient so as to reduce skin irritation. |
| US10780044B2 |
Natural and organic deodorant and method of making the deodorant
A method of making a natural antibacterial deodorant composition from the extract of Buchu leaf with arrowroot powder, sodium bicarbonate, witch hazel and aloe vera. The combination of these ingredients provide a natural deodorant that is safe and effective in eliminating bad odor, when the deodorant composition is applied to the body, the deodorant does not occlude the pores of the skin and permits sweating but is effective against malodors. |
| US10780042B2 |
Cosmetic compositions
Suggested is a cosmetic composition comprising an anti-pollution agent selected from the group consisting of E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one, sclareolide, purple coneflower pressed juice, ginger root CO2 extract or mixtures thereof, in a working amount sufficient for (a) reducing or preventing air pollution induced gene expression, and/or (b) reducing or preventing a gene expression induced or inducible by polycyclic aromatic hydrocarbons, and/or (c) reducing or preventing air pollution-induced or air pollution-inducible skin damage. |
| US10780040B2 |
Cosmetic compositions which are homogenous in the bulk and capable of forming a multilayer structure after application to a keratinous material
Cosmetic compositions capable of forming a multilayer structure after application to a keratinous material are provided, as well as methods of applying such compositions to keratinous material. Certain compositions comprise: Component A which comprises about 0.01% to 40% by weight with respect to the total weight of the composition of at least one silicone- and/or hydrocarbon-containing film forming agent having at least one glass transition temperature which is lower than normal human body temperature; and Component B which comprises about 0.01% to 90% by weight with respect to the total weight of the composition of one or more silicone compounds having a viscosity of greater than about 20 million cst, wherein the weight ratio of the silicone- and/or hydrocarbon-containing film forming agent(s) in Component A to silicone compound(s) in Component B of about 1:1.5 to about 1:100. |
| US10780038B2 |
Hair treatment agent containing at least one acid protein and at least one salt
A cosmetic agent for treating keratin fibers is provided herein. The cosmetic agent includes, in a cosmetically acceptable carrier, in relation to the total weight of the cosmetic agent, from about 0.001 to about 10 wt. % of at least one protein which has a content of glutamic acid and/or aspartic acid of from about 10 to about 60%, in relation to the total content of all amino acids of the protein. The cosmetic agent further includes, in a cosmetically acceptable carrier, in relation to the total weight of the cosmetic agent, from about 0.01 to about 10 wt. % of at least one salt which includes at least one divalent cation, and/or of at least one salt which includes at least one trivalent cation. |
| US10780033B2 |
Aloe derived mineral supplement
A method of maintaining or improving tissue health, maintaining or improving bone health, maintaining or improving cardiovascular health, or improving the appearance or texture of skin by administering a composition of the aloe rind minerals. The aloe rind minerals can be prepared from aloe rind by ashing or fermentation. Compositions can include aloe rind minerals and one or more additional active or inactive ingredients, and can be administered topically or orally. |
| US10780030B2 |
Carbonated cosmetic products containing polymers
Disclosed are compositions comprising at least one bicarbonate compound, at least one acid, at least one film forming polymer, and at least one cosmetically acceptable carrier, wherein the weight ratio of the at least one bicarbonate compound to the at least one acid is greater than or equal to about 1:1, and methods of altering the shape of keratin fibers comprising contacting the fibers with the compositions. |
| US10780026B2 |
Methods of forming dental composites and compositions for reduced shrinkage stress
A method of forming a dental composite includes photopolymerizing a dental composition. The dental composition includes a free-radically polymerizable (meth)acrylate resin, 75 percent by weight or greater of filler particles, and about 0.005 percent to about 5 percent by weight of at least one polymerizable stable radical. The photopolymerizing forms the dental composite such that the dental composite has a flexural modulus of about 9500 MPa or greater and the polymerizable stable radical reduces shrinkage stress of the dental composite caused by the photopolymerizing by 10% or greater. A method of forming a dental composite composition includes combining a free-radically polymerizable (meth)acrylate resin, 75 percent by weight or greater of filler particles, and about 0.005 percent to about 5 percent by weight of at least one polymerizable stable radical to form the dental composite composition. |
| US10780025B2 |
Apparatus and methods for oral administration of fluids and medical instrumentation
Methods and devices for orally administering fluids and medical instrumentation to individuals for the promotion of health are disclosed. An apparatus is described comprising a cartridge including a cartridge body defining a reservoir and a cartridge spout extending proximally from the cartridge body and terminating at an aperture. A cartridge seal is attached to a proximal tip of the cartridge spout, wherein the cartridge seal hermetically seals the liquid within the cartridge, and wherein the cartridge seal is detachable from the proximal tip of the cartridge spout and permanently coupled to the cartridge at a location distal to the cartridge spout. A proximal cartridge seal portion is positioned proximal to the location of permanent coupling and is moveable away from the cartridge aperture once the cartridge seal is detached from the proximal tip of the cartridge spout. |
| US10780023B2 |
Healthcare management services
Systems, methods, and computer-readable media for a healthcare management service are provided. |
| US10780021B2 |
Cycloolefin polymer container with a scratch resistant and anti-static coating
Cycloolefin polymer (COP) containers, including vials or syringes, having a scratch-resistant and anti-static coating on the external wall results in a reduction or prevention of static charge on the articles. The combination of an anti-scratch and anti-static coating results in the reduction of the attraction of charged particles to the container, leading to decreased particulate contamination while providing scratch resistance. |
| US10780018B2 |
Squeeze roller for MyoFascial release
A device for redirecting force to release tension in muscles and fascia in a body part. |
| US10780013B1 |
Assistive cane and reach extension combination device
An assistive cane and reach extension combination device for improved stability and reach includes a shaft. A handle that is coupled to and extends from of the shaft is configured to be grasped in a hand of a user, positioning the shaft to transfer a load from the handle to a surface upon which the user is positioned. A bar that is hingedly coupled to the shaft proximate to the handle is selectively positionable in a stowed configuration, wherein the bar is substantially parallel to the shaft, and a deployed configuration, wherein the bar is selectively positionable transversely to the shaft. In the deployed configuration the bar and the shaft are configured to insert an article. An actuator that is coupled to the shaft is operationally coupled to the bar so that the actuator is positioned to selectively motivate the bar toward the shaft to grasp the article. |
| US10780010B2 |
Reduced friction surface and method of use
A plurality of ball transfer units is used together to form a reduced friction surface. The reduced friction surface lies on a base, and is particularly useful for carrying out a physical activity on, or applying force to, a body part on the surface so as to stretch the muscles and stretch and/or decompress the spine. |
| US10780008B2 |
Oscillating hospital bed aimed at preventing decubitus ulcer
Oscillating hospital bed that smoothly changes the body support points to vary the effective area of body support on the bed with slow, constant oscillations, in the directions of the width and length of a mattress support, characterized by having sets of drive systems attached to a chassis which supports other components, such as an electric motor, a control panel, a thread vertical shaft, a rotation shaft and noise and vibration absorbing cushions. |
| US10780002B2 |
Pant-like absorbent article
A pant-type absorbent article has a longitudinal direction, a transverse direction, an inner surface facing the user during use, an outer surface facing away from the user during use. The article includes: a first body portion, a second body portion and an intermediate crotch portion provided with two leg openings. Outer longitudinal edge portions of the first body portion are adapted to be interconnected to outer longitudinal edge portions of the second body portion by first and second longitudinal refastenable side seam configurations. Each one of the refastenable side seam configurations includes a fastening component bonded to an outer longitudinal edge portion of the first body portion and a mating fastening component bonded to a corresponding outer longitudinal edge portion of the second body portion. Moreover, each one of the fastening components and the mating fastening components includes a first mechanical connector structure and a second mechanical connector structure. |
| US10779995B2 |
Process for dosing super absorbent particles
The present invention is directed to a novel process for dosing super absorbent polymer particles into a plurality of particles flows, comprising the steps of: (i) providing super absorbent polymer particles; (ii) imparting a rotation to said particles; and (iii) collecting separate flows of particles, wherein the step (ii) is performed with a rotating mobile (11) provided into a housing (12).Use for manufacturing absorbent article and article thus obtained. |
| US10779992B2 |
Hearing protection devices and attenuation button for same
A manually, selectively attenuating earplug button is disclosed, for insertion into a cavity of an earplug of a hearing protection device The earplug button comprises a nested configuration of a first housing member (including a first opening to receive sound from an ambient environment) and a second housing member, surrounding the first housing member and including a second opening to output at least a portion of the sound passing through an audio channel located between said first and second openings The first and second housing members include sidewall apertures for permitting a wearer to manually adjust the amount of sound admitted to the wear's ear from said ambient environment by rotating the first housing member (and thus its sidewall aperture) with respect to the second housing member. |
| US10779989B2 |
Device and method for a laser-assisted eye-surgery treatment system
The invention relates to an apparatus for a laser-assisted eye-surgery treatment system, comprising a first image-acquisition unit that is designed to acquire a first image (39) of an eye to be treated. The apparatus further comprises a computer arrangement which is designed to detect at least one first feature (40′) of the eye by means of image processing of the first image, and to determine a position and an orientation of the first feature in a coordinate system (S′) of the treatment system. The computer arrangement is also designed to determine a position and an orientation of an incision (66′) to be produced in the eye in the coordinate system (S′) of the treatment system as a function of the determined position and orientation of the first feature (40′) in the coordinate system and as a function of a previously determined relative position and orientation of at least one second feature (64′) of the eye with respect to the first feature (40′). |
| US10779986B2 |
Device for cleaning a stoma in a human or animal body
The invention relates to a device for cleaning a stoma in a human or animal body. The object of the invention is to provide a device as described in the introduction which completely abuts the skin's surface, irrespective of the location of the stoma on the body and irrespective of the person's or animal's build. In order to achieve that object, the device is according to the invention characterised in that the circular contact edge of the container is provided with a circular flexible collar comprising at least a first circumferential edge and a second circumferential edge, which first circumferential edge and second circumferential edge enclose an air chamber when placed on the body. |
| US10779985B2 |
Adapter insert for an ostomy guard
An adapter insert is for the purpose of reinforcing or stiffening a flexible adapter for said guard system to provide greater support and stabilization in the peristomal region in an effort to help reduce herniation, and to help aid adhesion of a faceplate when worn short term without a guard when output is expected to be minimal, for instance, between meals. The conjoined insert and adapter are positioned between a faceplate and a pouch, their inner apertures surrounding the faceplate flanges or heat weld of an ostomy appliance, and worn under form-fitted clothing negating the need for a security strap. |
| US10779980B2 |
Intragastric device for treating obesity
A intragastric device that contains a compressible free-floating structure and a sleeve attached thereto is provided. The device is considered to be anchorless as the sleeve is not physically attached to any portion of the GI tract. The device is configurable between a compressed pre-deployment configuration and an expanded post-deployment configuration. The free-floating device may be composed of a shape memory material such a nitinol. In some embodiments, the free-floating structure is space occupying and non-porous. The sleeve may be attached to the free-floating structure, such as with sutures and/or glue. In some embodiments, a stent may be inserted at the proximal end of the sleeve. A second free-floating structure may be connected to the free-floating structure such that there is an upper structure and a lower structure. In some embodiments, the gastrointestinal device is used to deliver prebiotic and/or probiotic therapy to a patient. |
| US10779977B2 |
Variable scale stent deployment device
A variable scale medical implant deployment device comprising a variable inner diameter scale sleeve insert is provided. Also described are kits containing the variable scale medical implant deployment device and methods for deploying a medical implant into a body lumen using a variable scale medical implant deployment device. |
| US10779970B2 |
Devices and methods for treating aneurysms and other vascular conditions
A fenestrated aortic cuff is configured to be delivered endovascularly to a target region, deployed, fastened, and sealed to a vessel wall, e.g., in a neck region of an aortic aneurysm. Example fenestrated cuffs provide a suitable landing zone for a commercially available endograft, which may be, in some cases, positioned below or above the renal arteries in order to complete exclusion of an abdominal aortic aneurysm (AAA) or a thoracic aortic aneurysm (TAA), respectively, from systematic circulation. In some cases, fenestrated cuff function is facilitated and improved by employing active fixation and sealing mechanisms, including, e.g., helical fasteners, which may allow deployment of the fenestrated cuff in short neck regions with limited sealing area. |
| US10779969B2 |
Endovascular implant and deployment devices
A plaque tack can be used for holding plaque against blood vessel walls such as in treating atherosclerotic occlusive disease. The plaque tack can be formed as a thin, annular band for holding loose plaque under a spring or other expansion force against a blood vessel wall. Focal elevating elements and/or other features, such as anchors, can be used to exert a holding force on a plaque position while minimizing the amount of material surface area in contact with the plaque or blood vessel wall and reducing the potential of friction with the endoluminal surface. This approach offers clinicians the ability to perform a minimally invasive post-angioplasty treatment and produce a stent-like result without using a stent. |
| US10779968B2 |
Endoluminal device and method
An endoluminal device can be configured for precise positioning during deployment within a vessel. The endoluminal device can be a tack, stent, vascular implant or other type of implant. The endoluminal device can have circumferential member with an undulating configuration having multiple inward and outward apexes and struts extending therebetween. Two of the struts can be used to establish a foot for the precise positioning of the device during deployment. A method of placing the endoluminal device can include withdrawing an outer sheath such that a portion of the endoluminal device is expanded prior to the rest of the endoluminal device. |
| US10779965B2 |
Posts with compliant junctions
Apparatus and methods are described, including a stent configured to be placed in a lumen. The stent includes a generally cylindrical stent body comprising a plurality of struts, and a plurality of antenna posts protruding longitudinally from an end of the stent body. Each of the antenna posts includes a proximal and distal portions, each of which is configured to be generally straight in the absence of any force being applied to the antenna post, and a compliant junction disposed between the proximal and distal portions, the proximal and distal portions being configured to flex with respect to one another about the compliant junction. An antenna is disposed annularly on the distal portions of the antenna posts, such that the antenna posts separate the antenna from the end of the stent body. Other applications are also described. |
| US10779960B2 |
Engineered sterile cartilage allograft implant plug with sterile, specific instrument kit(s)
An apparatus and a method are provided for performing cartilage allograft implant surgeries. The apparatus comprises an allograft plug kit comprising one or more grafts configured to treat osteochondral defects in various bone joint locations in a patient's body. Each of the grafts comprises a cartilage layer coupled with a bone portion. The cartilage layer comprises a thickness selected to closely match the thickness of existing cartilage at an implant location. The bone portion comprises surface features configured to encourage the patient's bone tissue to grow into the bone portion, thereby accelerating incorporation of the graft into the patient's bone. An instrument kit comprises a multiplicity of instruments configured for implantation of the grafts into the patient's body, including at least a graft inserter, a guidewire, a reamer, and a size gauge. |
| US10779957B2 |
Expandable fusion device and method of installation thereof
The present invention provides an expandable fusion device capable of being installed inside an intervertebral disc space to maintain normal disc spacing and restore spinal stability, thereby facilitating an intervertebral fusion. In one embodiment, the fusion device includes body, a first endplate, and a second endplate, a middle ramp piece, a stem, and two ramp pins. The middle ramped piece is operable to move to generate lordotic expansion of the first and second endplates followed by parallel expansion. The fusion device is operable to be deployed down an endoscopic tube. |
| US10779956B2 |
Systems and methods for inserting an expandable intervertebral device
An expandable interbody device for implantation within an intervertebral space is provided, together with methods and tools for use therewith. The interbody devices of the present invention include upper and lower bearing members configured to expand via an expansion mechanism configured to allow the insertion of osteoconductive materials and other structures into the interior of the interbody device before and after implantation, and before and after expansion of the interbody device. The insertion tool is configured expand the interbody device and to allow insertion of materials into the interbody device through a protected pathway. |
| US10779954B1 |
Body density scan result-matched orthopedic implants and methods of use
A method of treating a patient who requires surgical implantation of an orthopedic implant is described. The method includes the steps of: determining the DEXA scan T-score of the patient's native bone at a site of surgical implantation where the implant will be in contact with the patient's native bone; retrieve from among three or more implants of the same type an implant that has a density that is closest to the density of the patient's native bone at the site of surgical implantation based on the DEXA scan T-score of the patient's native bone; and implanting the retrieved implant in the patient to the exclusion of the other two or more implants. |
| US10779953B2 |
Vertebral implant, vertebral fastening device of the implant and implant instrumentation
This disclosure provides vertebral implants, fastening devices for vertebral implants, and implant instrumentation, and various combinations thereof. In some embodiments, the implant comprises a peripheral wall extending according to a vertical axis between upper and lower surfaces of the implant, with each such surface configured to be placed in contact with a vertebral structure, respectively, at the top and the bottom of the vertebral segment replaced by the implant. Some embodiments comprise fastening means, deployment of which anchors the implant in the lower and upper vertebral structures. Some fastening means may be deployed by sliding parallel to the vertical axis of the implant, and may comprise a plate with at least one part remaining in contact with the peripheral wall of the implant when deployed and a pointed end projecting from one of the upper and lower surfaces of the implant to enter a vertebral structures on completion of deployment. |
| US10779952B2 |
Methods and devices for less invasive glenoid replacement
The invention relates to a glenoid (shoulder socket) implant prosthesis, a humeral implant prosthesis, devices for implanting glenoid and humeral implant prostheses, and less invasive methods of their use for the treatment of an injured or damaged shoulder. |
| US10779935B2 |
Cardiac stent-valve and delivery device for such a valve
A cardiac stent-valve (1), preferably a mitral stent-valve, comprising a stent component (2) and a valve component (3), wherein the stent component (2) comprises an inflow end (4) and an outflow end (5) and a wall between the inflow (4) and the outflow end (5), and wherein the valve component (3) is made of one single leaflet (6); the periphery of said single leaflet (6) being partially attached or attachable to the stent component (2) along at least fixation lines (7′, 7″), characterized in that said two fixation lines (7′) are at least partially inclined with respect to an annular plane of said valve perpendicular to a flow direction (A) through the stent-valve (1) and wherein the third fixation line (7″) runs parallel with respect to said plane. |
| US10779932B2 |
Systems and methods for preparing reinforced graft constructs
Systems and methods for preparing a tissue repair construct for a ligament reconstruction procedure using a reinforced whip-stitching are provided. The described techniques include passing a needle having suture tails attached thereto through a first surface of a graft at an origin point so that a portion of the suture tails exits on a second, opposite surface of the graft while a terminal length of the suture tails is maintained on the first surface of the graft. Multiple suture loops are formed by repeatedly passing the needle with the suture tails around opposite sides of the graft and through the first surface of the graft at subsequent entry points spaced apart along a length of the graft. Each loop is formed so that the construct is reinforced by having a terminal length of each of the suture tails disposed between the first surface of the graft and the loop. |
| US10779921B2 |
Oral cavity washing device
An oral cavity washing device includes a body unit including a pump configured to discharge washing liquid, a tube connected to the body unit and configured to allow the discharged washing liquid to flow through the tube, a washing unit connected to the tube and configured to discharge the washing liquid, a joint portion configured to detachably attach the washing unit to the body unit, a disposing portion provided at the body unit and configured to allow the tube to be disposed at the disposing portion in a state where the washing unit is attached to the body unit, and an elastic member provided at the disposing portion. |
| US10779916B2 |
Milling block, method for producing partial or total prostheses, and complete milling block system
The invention relates to a milling block (1) for producing partial or total prostheses, comprising a prosthesis base (3) to be processed according to the shape of the jaw, on which synthetically moulded teeth (5), preferably a full set of teeth, are provided, a milling block system consisting of a first milling block for the upper set of teeth and a second milling block for the lower set of teeth, and a method for producing partial or total prostheses. |
| US10779913B2 |
Bendable impression tray and method of taking an impression therewith
A bendable impression tray includes a base portion and a handle portion. In one embodiment, the bendable impression tray includes a U-shaped portion and at least three projections extending outwardly from the U-shaped portion by at least 5 millimeters in bottom view. In one embodiment, the bendable impression tray includes a base portion that is substantially U-shaped in bottom view, and defines at least two peripheral notches, each extending inwardly from an outer periphery of the base portion by at least 5 millimeters in bottom view. |
| US10779912B2 |
Dental implant system
A dental implant and final prosthetic placement system for small-diameter implants (and method for using the system) in which a final prosthetic is digitally designed and created, and is itself used as the drill guide to place the implants. The final prosthetic is held in the predetermined proper drilling position by a stent, such as an occlusal guard. The combination of final prosthetic (with holes through which the small-diameter implants are drilled to secure it) and the stent encasing the final prosthetic, is itself the drill guide. |
| US10779911B2 |
Orthodontic system with an archwire couplable to an element
An element intended for an orthodontic system comprises: a fixing surface to be attached to the wall of a tooth; a body, having sides counterposed with respect to the fixing surface and defining a groove passing through sides, for housing an arch wire that can be removed and protrudes while being kept in the groove through at least one of sides with respect of the element; a slit passing through the sides toward the groove in order to assemble the archwire in the groove. In this way the play between the arch wire and the hole is lower than the space between the archwire and the groove, in order to keep the archwire in the body. |
| US10779910B2 |
Orthodontic bracket axis indicator
An orthodontic bracket axis indicator for use with an orthodontic bracket including a long slot intersecting with an archwire slot having a base surface and first and second opposed slot surfaces extending from the base surface includes an insert having first and second elongate cross members having first and second top surfaces, respectively, and arranged generally perpendicular to each other such that, when viewed from above, the insert has a generally cruciform shape. First and second grooves extend along the first and second top surfaces of the first and second cross members, respectively, and are each configured to receive an orthodontic tool. The first cross member is configured to be received by the archwire slot and the second cross member is configured to be received by the long slot in order to provide an interference fit between the insert and the orthodontic bracket. |
| US10779908B2 |
Systems and method for protection of optical system of laser-based apparatus
In an apparatus for directing a laser beam to a dental treatment area, where the apparatus includes a hand piece having an optical subsystem including a turning mirror for directing a laser beam to a treatment area via an orifice of the hand piece, a fluid supply subsystem creates a fluid flow within the hand piece proximate the turning mirror so as to mitigate contamination thereof. |
| US10779904B2 |
Systems and methods for lesion formation and assessment
Catheter for visualizing ablated tissue comprises a catheter body; a distal tip positioned at a distal end of the catheter body, the distal tip defining a illumination cavity, the distal tip having one or more openings for exchange of light energy between the illumination cavity and tissue; a light directing member disposed within the illumination cavity, the light directing member being configured to split light energy received from a light source into multiple beams and to such beams to the tissue through the corresponding more openings in the distal tip. |
| US10779903B2 |
Positive shaft rotation lock activated by jaw closure
A surgical instrument includes a housing, a shaft assembly, and a rotation locking mechanism. The shaft assembly extends distally from the housing and includes a shaft portion defining a longitudinal axis, and an end effector extending distally from the shaft portion, wherein the end effector and the shaft portion are axially rotatable relative to the housing about the longitudinal axis. The end effector includes a first jaw and a second jaw movable relative to the first jaw to transition the end effector between an open configuration and a closed configuration. The rotation locking mechanism is configured to prevent an axial rotation of the end effector and the shaft portion relative to the housing in the closed configuration. The rotation locking mechanism is configured to permit the axial rotation of the end effector and the shaft portion relative to the housing in the open configuration. |
| US10779902B2 |
Active and semi-active damping in a telesurgical system
A surgical system includes methods and systems for damping vibrations. The surgical system can include one or several moveable set-up linkages. A passive, active, or semi-active damper can be connected with one or several of the set-up linkages. The damper can mitigate a vibration arising in one of the set-up linkages and the damper can prevent a vibration arising in one of the linkages from affecting another of the set-up linkages. The active and semi-active dampers can be controlled with a feedback or a feed-forward model. In some embodiments, the system includes a first link supported by a base, a second link, a damper having a variable portion coupling the first link to the second link, and a processor. The processor is configured to detect a movement or a vibration of the second link and adjust the variable portion of the damper based on the detected movement or vibration. |
| US10779901B2 |
Robotic surgical system having a communication network of a ring topology and method for use therewith
A robotic surgical system is disclosed having a ring network for communicating information between a controller and nodes of one or more robotic arms. A communications protocol is described by which synchronous and asynchronous information can be communicated to and from the nodes of the robotic arms. Also disclosed are various aspects of a physical layer that can be used with the network. |
| US10779891B2 |
System and method for navigation of surgical instruments
An apparatus includes a navigational guidewire and a connector assembly. The navigational guidewire includes a sensing element, an outer member, and a conductor. The sensing element is configured to respond to positioning within an electromagnetic field. The conductor is in communication with the sensing element. The connector assembly is configured to couple the navigational guidewire with a navigation system. The connector assembly includes a body and a ferrule. The ferrule is coupled with the body. The navigational guidewire is coupled with the ferrule. The ferrule is rotatable relative to the body to thereby enable rotation of the navigational guidewire relative to the body. |
| US10779888B2 |
Smoke dissipation adapter for laser handpieces
An adapter for attachment to a medical application device includes an energy generating device and a distal tip for applying the energy generated to skin tissue. The adapter includes a substantially hollow body with a distal end portion and a proximal end portion. The proximal end portion is sized to mount on the distal tip of the energy generating device; the distal end portion is substantially open. The adapter further includes at least one through port extending from the proximal end portion to the open distal end portion of the adapter. |
| US10779886B2 |
Thermal therapy systems and methods
Devices and methods can be used to deliver thermal therapy to treat tissue. For example, this document provides devices and methods for treating varices, varicosity, other bleeding vessels, polyps, and cancer using microwave-delivered thermal therapy in a minimally invasive fashion. In some embodiment's provided herein, a multidirectional thermal therapy that does not injure surface tissues but causes endothelial injury and coagulation is described. In some implementations, varices are suctioned into a cup that is configured to deliver thermal therapy to the varices, resulting in coagulation. |
| US10779885B2 |
Apparatus and methods for the treatment of tissue using microwave energy
Systems and methods for delivering microwave energy to skin are provided, such that a focal zone of destructive heat is generated in the upper sub-dermis, mid-dermis, and/or lower dermis. This microwave therapy may be used for hair removal, treatment of acne, skin tightening, treatment of toe nail fungus, or sweat reduction. According to one embodiment, a system can include a microwave applicator having a distal treatment portion that includes at least one microwave antenna, a cooling system, and vacuum features. In some embodiments, the interaction between incident waves transmitted from the microwave applicator and reflected waves may be used to generate a standing wave with a peak energy density in selected regions of the dermis. |
| US10779884B2 |
Energy facilitated composition delivery
A device for delivering a composition to a hollow body region is disclosed. In one aspect, the device comprises a first longitudinal member and a second longitudinal member. Both of the longitudinal members may comprise conductive electrodes. The longitudinal members are further configured to be connected to an energy source such that the conductive electrodes are configured to generate an energy field. At least one of the longitudinal members further comprises a delivery element configured to deliver at least one composition to the body region, such that the composition is delivered in a direction that is influenced by the generated energy field. In one aspect, the body region is a vessel comprising an occlusion. |
| US10779883B2 |
Epicardial access system and methods
A method and apparatus are disclosed for a needle for gaining access to the pericardial cavity of a heart. The needle includes an elongate member (e.g. a main shaft) defining a lumen and a side-port in communication with the lumen; a blunt atraumatic tip for delivering energy for puncturing tissue; and a guiding surface (e.g. a ramp) for directing a device (e.g. a guidewire) through the side-port. The method includes using the needle for tenting a pericardium and delivering energy for puncturing the pericardium, and advancing a guidewire or other device through the needle and into the pericardial cavity. |
| US10779881B2 |
Surgical instruments and methods for performing tonsillectomy and adenoidectomy procedures
A method of surgery includes grasping tissue between tissue-treating plates of first and second jaw members. One or both of the jaw members includes a bifurcated body having first and second jaw components. Each jaw component includes a tissue-treating plate portion disposed thereon. The tissue-treating plate portions cooperate to define the tissue-treating plate of the jaw member. The method further includes energizing the tissue-treating plates of the first and second jaw members for conducting energy through grasped tissue to treat grasped tissue and separating grasped and treated tissue by rotating at least one of the first and second jaw components of the at least one jaw member relative to the other from an aligned orientation, wherein the tissue-treating plate portions are substantially co-planar relative to one another, to an angled orientation, wherein the tissue-treating plate portions are angled relative to one another. |
| US10779879B2 |
Detecting short circuits in electrosurgical medical devices
An electrosurgical system for providing an electrosurgical signal to a patient is disclosed. The electrosurgical system includes a control circuit, wherein the control circuit is programmed to: provide the electrosurgical signal to a first electrode and a second electrode, receive a plurality of input variables, wherein the plurality of input variables are indicative of a short being either present or absent between the first electrode and the second electrode, and apply a short detection algorithm to the plurality of input variables to indicate either a short circuit or no short circuit between the first electrode and the second electrode during the provision of the electrosurgical signal. The plurality of input variables may include at least one impedance level between the first electrode and the second electrodes during the provision of the electrosurgical signal. The short detection algorithm applied may include a fuzzy logic algorithm, a neural network algorithm, or neuro-fuzzy algorithm. |
| US10779877B2 |
Power modulated endometrial lining tissue ablation
A system is configured to delivering radiofrequency power to the endometrial lining tissue of a uterine cavity, including modulating the delivered power so that a measured impedance of the endometrial lining tissue tracks a target impedance as a function of time, wherein the target tissue impedance is derived from a function that approximates a preferred endometrial lining tissue ablation impedance curve that is determined based upon a measured impedance of the endometrial lining tissue after RF power has been delivered for a predetermined initial time period. |
| US10779876B2 |
Battery powered surgical instrument
A medical instrument is disclosed. The medical instrument includes at least one electrical contact element, a battery, a radio frequency (RF) generation circuit coupled to and operated by the battery and operable to generate an RF drive signal and to provide the RF drive signal to the at least one electrical contact, and a battery discharge circuit coupled to the battery. A processor is coupled to the battery discharge circuit and a memory is coupled to the processor. The memory stores machine executable instructions that when executed cause the processor to monitor activation of the RF generation circuit and disable the RF generation circuit when the RF drive signal is fired a predetermined number of times. The medical instrument may include an activation switch and/or a disposal switch supported by the housing. |
| US10779875B2 |
Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment
Tumors can be treated with an alternating electric field. The size of cells in the tumor is determined prior to the start of treatment by, for example, biopsy or by inverse electric impedance tomography. A treatment frequency is chosen based on the determined cell size. The cell size can be determined during the course of treatment and the treatment frequency is adjusted to reflect changes in the cell size. A suitable apparatus for this purpose includes a device for measuring the tumor impedance, an AC signal generator with a controllable output frequency, a processor for estimating the size of tumor cells and setting the frequency of the AC signal generator based thereon, and at least one pair of electrodes operatively connected to the AC signal generator such that an alternating electric field is applied to the tumor. |
| US10779874B2 |
Methods and systems for treating urinary stress incontinence
The systems and methods in accordance with the principles of the invention can treat urinary stress incontinence by treating target tissue in proximity to the urethra and/or bladder neck. A method for treating urinary stress incontinence in a subject can included non-invasively heating a subsurface region of a target tissue to induce remodeling of the subsurface region at the anterior and/or posterior regions of the vagina. The system can include: a controller and a probe having a distal end configured for non-invasive contact with a surface of a target tissue to transfer energy to the target tissue based on treatment parameters. The probe distal end can have two treatment surfaces spaced apart a distance equal to at least a width of a urethra. |
| US10779872B2 |
Bone anchor insertion instruments and methods
Surgical instruments and methods for implanted bone anchor assemblies into bone are disclosed herein. In one exemplary embodiment, an instrument is provided having an anchor drive assembly and a stylet assembly. The anchor drive assembly can have a first handle and an elongate shaft having a distal tip configured to couple to a bone anchor assembly. The stylet assembly can have a second handle and a stylet extending through the elongate shaft. The instrument can have a disengaged position and an engaged position such that rotation of the first handle is effective to drive the bone anchor assembly into bone only when the instrument is in the engaged position, and rotation of the second handle is effective to cause axial translation of the stylet relative to the elongate shaft. |
| US10779869B2 |
Implant device
An implant device is used for maintaining a distraction or compression element and includes a rod linked to implants by support devices having a threaded stud and a head for interaction with a support piece. The support piece has a device for attaching and blocking a distraction or compression element. The threaded piece includes two zones, namely a distal end zone having a conical profile and a screw thread with wide turns, configured for cancellous bone, and a proximal zone having a conical profile with a conicity angle smaller than the conicity angle of the distal portion, with a narrow screw thread, configured for bone cortex, namely including sharp, thin, deep screw threads, whereas the web is flat. |
| US10779865B2 |
Spinal cross connector
A spinal cross-connector comprises an elongated member, a first connector and a second connector. The first connector and the second connector are configured to receive spinal rods and adaptable to directly attach with pedicle screws. The first connector includes a first collet head, a first clamp and a first locking means. The second connector includes a second collet head, a second clamp and a second locking mans. The first locking means is configured to tighten over a first collet head and engage with the first connector. Similarly, the second locking means is configured to tighten over a second collet head and engage with the second connector. The engagement of the first locking means with the first connector and the second locking means with the second connector locks the spinal cross-connector. |
| US10779862B2 |
Coupling assembly for coupling a rod to a bone anchoring element, and polyaxial bone anchoring device
A coupling assembly for coupling a rod to a bone anchoring element, including a receiving part having first and second ends, a recess at the first end for the rod, and an accommodation space for a head of the bone anchoring element, the accommodation space having an opening at the second end to permit insertion of the head into the receiving part, a retainer element configured to be arranged at least partially in the accommodation space and to hold at least part of the head, and a spring element configured to be arranged at least partially in the accommodation space and to be compressed in an axial direction. The retainer element and the spring element are separate parts. When the retainer element and the spring element are in the accommodation space of the receiving part in a first position, the spring element extends into the recess of the receiving part. |
| US10779850B2 |
Rotational tissue cutting control device
Disclosed embodiments include apparatuses and systems for controlling an apparatus for cutting an opening in a tissue wall. In an illustrative embodiment, an apparatus for controlling a counter-rotatable cutting apparatus includes a first radial actuator configured to engage a first drive shaft. A second radial actuator is configured to engage a second drive shaft, the second drive shaft being coaxially disposed with the first drive shaft. A housing supports the first radial actuator and the second radial actuator and permits the first drive shaft and the second drive shaft to extend therethrough, the first drive shaft and the second drive shaft being relatively counter-rotatable responsive to rotation of at least one of the first radial actuator and the second radial actuator. |
| US10779846B2 |
Surgical clamping device with parallel closure
A surgical clamping device includes a handgrip, an actuation assembly, an elongated body portion, an upper jaw assembly, and a lower jaw assembly. Each of the upper and lower jaw assemblies includes and an elongated jaw body and a distal clamping portion that is supported on a distal end of a respective elongated jaw body. Each of the elongated jaw bodies includes a proximal end that is pivotally connected to the actuation assembly by a pivot member located within the handgrip. The pivot member is spaced from the distal clamping portions of the upper and lower jaw assemblies such that the distal clamping portions of the upper and lower jaw assemblies remain substantially parallel as the upper and lower jaw assemblies are pivoted between open and clamped positions. |
| US10779836B2 |
Replaceable left atrial appendage occluder and an implanting method thereof
A replaceable left atrial appendage occluder includes a stepped balloon and an occlusion disc. The left atrial appendage orifice occlusion portion of the stepped balloon is configured to completely occlude the left atrial appendage orifice. The left atrial anchor portion of the stepped balloon is configured to be clamped on the left atrial wall to prevent the left atrial appendage occluder from shifting. The occlusion disc is released in the pericardial cavity, and is connected to the stepped balloon by the connecting column of the occlusion disc, so that the left atrial appendage is pressed and occluded between the stepped balloon and the occlusion disc. The stepped balloon occludes the left atrial appendage orifice. The surface of the stepped balloon is smooth and coated with an anticoagulant coating. |
| US10779833B2 |
Anvil assembly delivery system
An anvil assembly suitable for trans-oral delivery is provided. The anvil assembly includes a housing configured to receive a guide suture that is severed during a stapling procedure. An anvil delivery assembly including the anvil assembly and a suture guide assembly secured to the anvil assembly is also provided. |
| US10779822B2 |
System including a surgical cutting and fastening instrument
A surgical cutting and fastening instrument comprises an end effector that has a shaft coupled thereto that is coupled to a robotic system. A tool mounting portion includes an electric, DC motor connected to a drive train in the shaft for powering the drive train. A power pack that comprises at least one charge-accumulating device connected to the DC motor for powering the DC motor is provided. |
| US10779821B2 |
Surgical stapler anvils with tissue stop features configured to avoid tissue pinch
Anvils for surgical devices designed to cut and staple tissue. The anvils include tissue stop arrangements for positioning the tissue to be cut and stapled in the device so that the tissue is stapled prior to being cut. The anvils are moved between open and closed positions by a corresponding closure member. The tissue stops and/or closure members are configured to avoid adjacent tissue from being pinched between the closure member and tissue stops when the anvil is in a closed position. |
| US10779819B2 |
Surgical device with tandem fasteners
A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains at least one anvil movable within the staple housing, the anvil has a proximal position and a distal position. When in the distal position a distal end of the anvil extends distal to the distal end of the staple housing. The housing contains a plurality of surgical fasteners each of which in the shape of a loop. At least one of the fasteners is placed around a portion of the anvil when in the distal position. The applier has a first mechanism for moving the anvil distally after a fastener has been deployed, and a second mechanism for moving the anvil distally after a fastener has been deployed. The second means is independent of the first means. |
| US10779818B2 |
Powered surgical stapling device
An end effector includes first and second jaw members moveable relative to one another. Each of the first and second jaw members including a tissue contacting surface opposing the tissue contacting surface of the other jaw member. The end effector includes a detection assembly that is disposed within the first or second jaw member that is configured to detect an attribute of tissue between the first and second jaw members. The detection assembly may include a light source configured to emit light towards tissue between the first and second jaw members or may include an ultrasound transducer configured to emit ultrasound energy towards tissue between the first and second jaw members. |
| US10779817B2 |
Three dimensional adjuncts
Stapling assemblies for use with a surgical stapler and methods for manufacturing the same are provided. Three dimensional adjuncts for use with a surgical stapling assembly and methods for manufacturing the same are also provided. |