Document Document Title
US10563284B2 Leaching copper-containing ores
A method of leaching copper-containing ores includes leaching copper-containing ores or concentrates or tailings of the ores or concentrates with a leach liquor in the presence of an additive that enhances the dissolution of copper from copper minerals in the ores and concentrates by forming a complex between (a) sulfur, that has originated from copper minerals in the ores, and (b) the additive. A method of leaching copper-containing ores includes leaching copper-containing ores or concentrates or tailings of the ores or concentrates with a leach liquor includes leaching copper-containing ores or concentrates or tailings of the ores or concentrates with a leach liquor in the presence of a nitrogen-containing organic complexing additive that forms a complex between sulfur, that has originated from copper minerals in the ores, and the additive.
US10563282B2 Induction heating device for metal strip
An induction heating device for a metal strip, including: an induction coil provided on one side or on both sides of a front face side or a reverse face side of a metal strip, and that induces an induction current in the strip when a primary current is passed through the coil, the induction current configuring a closed loop as viewed from a direction perpendicular to a metal strip face; plural magnetic cores disposed at a specific position, this being a position at a back face side of the coil and separated from the strip by a specific distance, to concentrate magnetic flux generated by the coil in the strip; and a moving mechanism coupled to the magnetic cores, and that moves the cores to increase or decrease a disposed number of the cores at the specific position disposed side-by-side along a metal strip width direction.
US10563281B2 Heat-treated steel sheet member and method for producing the same
A heat-treated steel sheet member having a composition including, by mass %: C: 0.05 to 0.50%; Si: 0.50 to 5.0%; Mn: 1.5 to 4.0%; P: 0.05% or less; S: 0.05% or less; N: 0.01% or less; Ti: 0.01 to 0.10%; B: 0.0005 to 0.010%; Cr: 0 to 1.0%; Ni: 0 to 2.0%; Cu; 0 to 1.0%; Mo: 0 to 1.0%; V: 0 to 1.0%; Ca: 0 to 0.01%; Al: 0 to 1.0%; Nb: 0 to 1.0%; REM: 0 to 0.1%; and the balance: Fe and impurities. The steel sheet member has a microstructure comprising mainly martensite and retained austenite of which a volume ratio is 0.2 to 1.0%, a number density of retained carbide in the steel sheet member having circle-equivalent diameters of 0.1 mm or larger is 4.0×103/mm2 or lower, a tensile strength is 1.4 GPa or higher, and a yield ratio is 0.65 or higher.
US10563279B2 High strength steel sheet having high Young's modulus and method for manufacturing the same
A high strength steel sheet having a high Young's modulus, the steel sheet having a chemical composition including, by mass %, C: 0.060% or more and 0.150% or less, Si: 0.50% or more and 2.20% or less, Mn: 1.00% or more and 3.00% or less, and one or both of Ti: 0.001% or more and 0.200% or less and Nb: 0.001% or more and 0.200% or less, in which the contents of C, N, S, Ti, and Nb satisfy the equation 500≤C*≤1300. The steel sheet has a microstructure including ferrite in an amount of 20% or more and martensite in an amount of 5% or more, in terms of area ratio, such that the average grain size of the ferrite is 20.0 μm or less and the inverse intensity ratio of γ-fiber for α-fiber is 1.00 or more in the ferrite and the martensite.
US10563278B2 Rail manufacturing method and manufacturing equipment
Rail-manufacturing equipment that performs forced cooling on at least a head of a hot rail hot-rolled at or heated to the austenite region temperature or higher. The rail-manufacturing equipment includes a head-cooling header configured to jet a cooling medium toward the head of the rail, a head thermometer configured to measure surface temperature of the head of the rail, and a controller configured to adjust jet of the cooling medium from the head-cooling header. The controller includes a temperature-monitoring unit configured to monitor measurement results by the head thermometer during the forced cooling, and a cooling-rate controller.
US10563274B1 Stave cooler system and method
A stave cooler system for cooling one or more cooling elements mounted in a metallurgical furnace. The system includes a stave cooler assembly having an inner end portion with an end part comprising a body and a number of fins extending from the body, each fin being formed to bend upon engagement of an outer part of each said fin respectively with an outer wall of the cooling element, to securely engage at least the outer part of each fin with an inner borehole wall partially defining the inner part when the end part is inserted into the inner part of the hole.
US10563272B2 Compositions comprising Metarhizium fungi and use thereof as a pesticide
The present disclosure relates generally to an entomopathogenic fungi, Metarhiziuim spp, and its use to control invertebrate pests of agricultural crops, in particular, invertebrate pests which affect cotton crops.
US10563269B2 Broad detection of dengue virus serotypes
Processes for detecting Dengue virus (DENV) nucleic acid in a sample are provided including producing an amplification product by amplifying DENV nucleotide sequence and detection of an amplification by hybridization of a probe or other technique. The processes use primers or probes with introduced mutations and or degenerate bases that provide excellent superiority in detection and serotyping of DENV in a sample.
US10563266B2 Neoantigen treatment prioritization using multivariate analysis based on: HLA genotype, self-similarity, similarity to known antigens, antigen expression levels and mutant allele frequency
Cancer immunology provides promising new avenues for cancer treatment but validation of potential neoantigens to target is costly and expensive. Analysis of MHC binding affinity, antigen processing, similarity to known antigens, predicted expression levels (as mRNA or proteins), self-similarity, and mutant allele frequency, provides screening method to identify and prioritize candidate neoantigens using sequencing data. Methods of the invention thereby save time and money by identifying the priority candidate neoantigens for further experimental validation.
US10563262B2 Biomarkers of traumatic brain injury
Provided is a method of diagnosing and/or monitoring mild traumatic brain injury (mTBI) or concussion in a subject. The method comprises determining a level of at least one miRNA in a saliva sample from the subject. Also provided is a sensor element, a detection system, composition and a kit for diagnosing and/or monitoring TBI, and a method of determining an appropriate treatment for a subject with suspected mTBI or concussion.
US10563260B2 Method of predicting a predisposition to QT prolongation
The present invention describes an association between genetic polymorphisms in the FAM13A1 (family with sequence similarity 13, member A1) gene and a predisposition to prolongation of the QT interval, and provides related methods for the prediction of such a predisposition, the administration of QT interval-prolonging compounds to individuals having such a predisposition, and determining whether a compound is capable of inducing QT prolongation.
US10563258B2 Method of making skin care compositions
A method for making a skin care composition by identifying connections between cosmetic agents and genes associated with one or more skin aging conditions. The method includes accessing a plurality of instances and at least one skin aging gene expression signature, comparing the at least one skin aging gene expression signature to the plurality of the instances, assigning a connectivity score to each instance based on the comparison and incorporating the cosmetic agent into a skin care composition when the connectivity score of the instance associated with the cosmetic agent has a negative correlation.
US10563253B2 Cartridge interface module
A cartridge interface module (CIM), configured to engage with a removable microfluidic cartridge in a nucleic acid analyzer system can include a fluidics component, which is configured to initiate and support a liquid extraction of nucleic acids from a biological sample contained in the removable microfluidic cartridge. The CIM also includes a polymerase chain reaction (PCR) assembly component which can be configured to initiate and support amplification of the extracted nucleic acids. The CIM may also include a high voltage electrodes component that is configured to initiate and support separation of the amplified nucleic acids into nucleic acid fragments in a separation channel of the removable microfluidic cartridge. The CIM also includes a detection optics component that can be configured to collect, detect, and direct label nucleic acid fragments. The CIM is configured to integrate with a microfluidic chip architecture of an inserted removable microfluidic cartridge.
US10563252B2 Ultrasensitive biosensors
The present invention is a biosensor apparatus that includes a substrate, a source on one side of the substrate, a drain spaced from the source, a conducting channel between the source and the drain, an insulator region, and receptors on a gate region for receiving target material. The receptors are contacted for changing current flow between the source and the drain. The source and the drain are relatively wide compared to length between the source and the drain through the conducting channel.
US10563247B2 Single-molecule mechanoanalytical DNA device for ultrasensitive sensing of analytes
A single-molecule mechanoanalytical real-time sensing device (SMART) comprising a molecular trawl and a DNA stem-loop structure that serves as a molecular dipstick, said trawl and said DNA stem-loop structure anchored by handles to two optically-trapped bead templates; said molecular trawl comprising multiple analyte recognition elements that exist in each of two separate DNA (pair) strands that act as two pincers, said pincers each having a nucleobase capable of catching an analyte in a media; said DNA stem-loop structure comprising a plurality of nucleotides in said loop and multiple base pairs in said stem; and wherein said DNA stem-loop is located generally opposite to said molecular trawl that is capable of reporting an amount of bound analyte target via mechanochemical transient events.
US10563246B2 Microfluidic device for production and collection of droplets of a fluid
A microfluidic device and method for producing and collecting single droplets of a first fluid, the device including a microfluidic platform having at least a droplet microchannel wherein is produced a flow of single droplets of the first fluid dispersed in a second fluid immiscible with the first fluid, the droplet microchannel having at least one inlet extremity and at least one outlet extremity for distributing the flow of droplets, the device further including: a collection device including a plurality of receiving areas adapted to collect at least one of the droplets, elements for changing the relative position of the collection device and the outlet of the microfluidic platform, elements for controlling the flow of droplets, and elements for synchronizing the flow of droplets at the outlet of the droplet microchannel and the relative movement of the collection device with regards to the microfluidic platform.
US10563244B2 Nanopatterned extracellular matrices enable cell-based assays with a mass spectrometric readout
The present disclosure provides methods in which adherent cells are treated with small molecules, cultured, lysed, and then analyzed by mass spectrometry to measure the activities of endogenous enzymes. The implementation of this method relies on the use of surfaces that are nanopatterned with cell adhesion ligands to mediate cell attachment and a peptide that is a substrate for the desired enzyme activity in the lysate.
US10563239B2 Process of using a plug flow hydrolysis reactor having a slurry introduction device
Provided herein is a process for hydrolyzing a cellulosic feedstock to produce sugar. The process comprises introducing a pretreated cellulosic slurry to an inlet region of a plug flow hydrolysis reactor using a slurry introduction device that reduces the axial momentum of the slurry at the surface of the reactor contents. The cellulosic feedstock slurry is hydrolyzed in the plug flow hydrolysis reactor by contacting the cellulosic feedstock with at least cellulase enzymes to produce glucose. Also provided herein is a vertically-oriented, unmixed downflow hydrolysis reactor for hydrolyzing a pretreated cellulosic feedstock slurry which comprises such a slurry introduction device disposed in a top region thereof.
US10563238B2 Method of producing a sugar liquid
A method of producing a sugar liquid includes steps (1) providing a pretreatment product of a first cellulose-containing biomass; (2) adding a second cellulose-containing biomass or a pretreatment product thereof in an amount ranging from 1 to 50% based on the solid content weight of the first cellulose-containing biomass pretreatment product of step (1), and carrying out hydrolysis by a filamentous fungus-derived cellulase; and (3) subjecting a hydrolysate of step (2) to solid-liquid separation to obtain a solution component and a hydrolysis residue, and filtering the solution component through an ultrafiltration membrane to recover the filamentous fungus-derived cellulase as a retentate and recover a sugar liquid as a permeate.
US10563236B2 Method for producing L-methionine
Provided is an enzymatic process for preparing L-methionine from diethyl disulfide.
US10563235B2 Method for producing L-methionine
Provided is a process for the preparation of L-methionine in an enzymatic reaction utilizing dimethyl disulfide (DMDS) a precursor of L-methionine, and an organic reducing compound. In the process, methyl mercaptan can be formed by the enzymatic hydrogenolysis of the DMDS.
US10563233B2 Cementation methods
The present invention provides methods for mineral precipitation and/or cementation of permeable or fractured non-porous materials using isolated urease.
US10563229B2 Methods for stabilizing production of acetyl-coenzyme a derived compounds
The present disclosure relates to the use of a switch for the production of heterologous non-catabolic compounds in microbial host cells. In one aspect, provided herein are genetically modified microorganisms that produce non-catabolic compounds more stably when serially cultured under aerobic conditions followed by microaerobic conditions, and methods of producing non-catabolic compounds by culturing the genetically modified microbes under such culture conditions. In another aspect, provided herein are genetically modified microorganisms that produce non-catabolic compounds more stably when serially cultured in the presence of maltose followed by the reduction or absence of maltose, and methods of producing non-catabolic compounds by culturing the genetically modified microbes under such culture conditions.
US10563222B2 Promoters for high level expression
The present invention provides for functional chimeric gene regulatory units capable of driving strong and sustained heterologous gene expression.
US10563220B2 Compositions and methods for efficient targeting of transgenes
The invention provides recombinant DNA molecules and constructs useful for providing efficient transgene sub-cellular localization of proteins in transgenic plants. Recombinant DNA molecules and constructs for conferring herbicide tolerance or resistance to plants are further provided, as well as plants exhibiting herbicide tolerance and methods for producing or utilizing such plants.
US10563214B2 Use of micropeptides for promoting plant growth
The present invention relates to the use of micropeptides (peptides encoded by microRNAs or “miPEPs”) for promoting plant growth.
US10563211B2 Recombinant microorganisms and methods for producing cannabinoids and cannabinoid derivatives
The present disclosure provides genetically modified host cells that produce a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative. The present disclosure provides methods of synthesizing a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative.
US10563210B2 Method for producing interleukin-2 protein using methylotrophic yeast
The present invention relates to a method for producing an interleukin-2 protein using methylotrophic yeast. The method for producing interleukin-2 according to the present invention shows high cell growth and protein synthesis rates by use of the established optimal cell line, and produces a large amount of a protein comprising interleukin-2 by use of the established optimal culture conditions utilizing methanol that is an inexpensive carbon source. In addition, the method according to the present invention isolates and purifies the protein by a simple process. Accordingly, the method according to the present invention highly pure interleukin-2, and thus has a significant effect on the mass-production of interleukin-2.
US10563204B2 Methods of treating cancer harboring hemizygous loss of TP53
Provided herein are methods of treating a patient having a cancer that exhibits (i) a hemizygous loss of the TP53 gene; (ii) a hemizygous loss of the POLR2A gene; and/or (iii) a decreased level of expression of a POLR2A gene product relative to a reference (i.e., control) expression level. The methods comprise administering a therapeutically effective amount of a POLR2A inhibitor (e.g., a nucleic acid that inhibits the expression of a POLR2A protein, an amatoxin, alpha-amanitin, or alpha-amanitin conjugated to a cell targeting moiety, such as an EpCAM antibody) to a patient having or determined to have (i) a hemizygous loss of the TP53 gene; (ii) a hemizygous loss of the POLR2A gene; and/or (iii) a decreased level of expression of a POLR2A gene product relative to a reference (i.e., control) level.
US10563195B2 Phosphate replacement mRNA cap analogs
The present disclosure relates to cap analogs, which can result in high levels of capping efficiency and transcription and improved translation efficiencies. The present disclosure also relates to methods useful for preparing cap analogs and using mRNA species containing such analogs, as well as kits containing the cap analogs.
US10563193B2 Multivalent glycopeptides that tightly bind to target proteins
The invention relates to a glycopolypeptide that includes one or more modified amino acid residues having a sidechain comprising a monosaccharide or an oligosaccharide, wherein the glycopolypeptide binds specifically to a carbohydrate-binding monoclonal antibody with an affinity of less than 100 nM. Immunogenic conjugates that include the glycopolypeptide, and pharmaceutical compositions that include the glycopolypeptide or the immunogenic conjugate are also disclosed. Various method of using the glycopolypeptides, immunogenic conjugates, and pharmaceutical compositions are disclosed, including inducing an immune response, inhibiting viral or bacterial infection, treating a cancerous condition, and detecting a neutralizing antibody.
US10563191B2 Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of tryptophanyl tRNA synthetases
Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
US10563190B2 Methods for producing abienol
The present disclosure relates to a novel method, expression vectors, and host cells for producing abienol by converting geranylgeranyl diphosphate (GGPP) to abienol in the presence of a combination of a class II diterpene synthase and a bifunctional class I/II abienol synthase.
US10563189B2 Compositions and methods comprising variant microbial proteases
The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant subtilisins suitable for laundry cleaning applications.
US10563185B1 Beta-glucosidase having improved enzymatic activity
A beta-glucosidase having improved enzymatic activity is disclosed. The amino acid sequence of the beta-glucosidase is a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of tyrosine at position 286 with phenylalanine, or a substitution of asparagine at position 639 with glutamate.
US10563184B2 Regulation of gene expression using engineered nucleases
The present disclosure is in the field of genome engineering, particularly targeted modification of the genome of a hematopoietic cell.
US10563182B2 DNA polymerases with increased 3′-mismatch discrimination
Disclosed are mutant DNA polymerases having increased 3′-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
US10563174B2 Proteins increasing pancreatic beta cell number and methods of use
Disclosed herein are bacterial proteins that increase pancreatic beta (β) cell number and/or proliferation, methods of increasing β cell number and/or proliferation using such proteins, and methods of treating or inhibiting diabetes in a subject by administering such proteins to the subject. In some embodiments, the protein has at least 80% sequence identity to the amino acid sequence set forth as any one of SEQ ID NOs: 1-7, or fragments thereof. Recombinant vectors including a nucleic acid encoding the protein (such as a nucleic acid encoding a protein with at least 80% sequence identity to any one of SEQ ID NOs: 1-7 or fragments thereof) operably linked to a heterologous promoter are also disclosed. Also disclosed are methods of identifying compounds that increase β cell number and/or proliferation by determining the effect of test compounds on β cell number or proliferation in zebrafish pancreas.
US10563171B2 Method for inducing differentiation of pluripotent stem cells into germ cells
The invention provides a method for inducing human primordial germ cell-like (PGC-like) cells from human pluripotent stem cells, with high efficiency and high reproducibility, and a cell surface marker for identifying human PGC-like cells. In particular, the invention provides a method for producing a human PGC-like cell from a human pluripotent stem cell, includes a step of producing a mesoderm-like cell by culturing a human pluripotent stem cell in a culture medium comprising activin A and a GSK3β inhibitor, and a step of culturing the mesoderm-like cell in a culture medium containing BMP. The invention also provides a method for producing an isolated human PGC-like cell, which includes the aforementioned two steps and the additional step of selecting a cell positive to at least one cell surface marker selected from the group consisting of PECAM (CD31), INTEGRINα6 (CD49f), INTEGRINβ3 (CD61), KIT (CD117), EpCAM, PODOPLANIN and TRA1-81.
US10563164B1 Plate reader
Reader and plate methods, operations, and systems for observing a biological sample are shown and described. In one embodiment, a reader device includes selecting a plate type between at least two plate type selections on a user interface. One embodiment includes aligning a peel plate within a tray holder nest to define a semi-fixed processing position. One embodiment includes transporting a peel plate from a loading position into a focal alignment with an imaging device for monitoring biological growth, when present.
US10563162B2 Microbial electro-photosynthesis
Methods and apparatus for growing photosynthetic organisms lacking Photosystem II (PSII) function using externally supplied electrons shuttled into the organism using redox mediators to improve photosynthetic output and to produce and recover chemicals of interest. By removing PSII, all PAR photons are funneled toward Photosystem I, thereby significantly increasing the theoretical photon utilization efficiency for CO2 fixation, energy storage and the capacity to synthesize valuable chemicals. Additional genetic modification can be performed to insert or enhance specific metabolic pathways to generate products of commercial interest.
US10563157B2 Method and device for controlled air injection into a vinification tank
A method and a device for air injection into a vinification tank (1) use air injection nozzles (2) installed therein. A rule is applied for automatic variation of injections with time, by a coordinated and combined action of the nozzles, so that for each of the installed nozzles the delivered air jets may be modulated in duration and frequency and combined with the jets delivered by the other nozzles according to a programmable sequence.
US10563155B2 Packaged composition
A packaged composition including a plurality of particles in a package, wherein the particles include: more than about 40% by weight of the particles of polyethylene glycol, wherein the polyethylene glycol has a weight average molecular weight from about 5000 to about 11000; and from about 0.1% to about 20% by weight of the particles of perfume; wherein substantially all of the particles in the package have a substantially flat base and a height measured orthogonal to the base and together the particles have a distribution of heights, wherein the distribution of heights has a mean height between about 1 mm and about 5 mm and a height standard deviation less than about 0.3.
US10563153B2 Rheology modified low foaming liquid antimicrobial compositions and methods of use thereof
The present disclosure relates to rheology modified, low foaming aqueous antimicrobial compositions. The compositions are phase stable under acidic conditions, and do not need to be rinsed from the surface to which they are applied. The present disclosure further relates to methods of use thereof.
US10563146B2 Preparation and use of aminoalkylphosphonic acid dilakyl ester compounds in a lubricant for antiwear, friction reduction, and/or micropitting prevention
In accordance with the disclosure, one aspect of the present application is directed to a lubricant additive composition. The lubricant additive composition includes a component or mixture of components selected from (a) an aminoalkylphosphonic acid dialkyl ester; (b) a cyclized product of an aminoalkylphosphonic acid dialkyl ester; and a mixture of (a) and (b). Preparation and use of the additive composition in a lubricant for antiwear and/or friction reduction are also disclosed.
US10563142B2 Development and implementation of analyzer based control system and algorithm
A method of correcting measurements of a chemical sensor used in an industrial facility. The method involves correcting for errors known to occur in the steady state and the dynamic state for specifically recognized situations. This method allows for correcting errors that occur due to deadtime, false zero measurements, and non-linear disturbances. The method combines automated measurement techniques and human know how to progressively learn and refine the accuracy of the corrections.
US10563137B2 Processes for removing nitriles from a feed to an oligomerization zone
Processes for regenerating adsorbent in a nitrile removal zone. The regenerant comprises a stream of hot liquid that may comprise a portion of the oligomerized effluent or a portion of a hydrotreated effluent. A spent regenerant comprising the desorbed nitriles may be processed along with the oligomerized effluent with existing separation equipment.
US10563134B2 Catalyst and its use for the selective hydrodesulfurization of an olefin containing hydrocarbon feedstock
A catalyst and its use for selectively desulfurizing sulfur compounds present in an olefin-containing hydrocarbon feedstock to very low levels with minimal hydrogenation of olefins. The catalyst comprises an inorganic oxide substrate containing a nickel compound, a molybdenum compound and optionally a phosphorus compound, that is overlaid with a molybdenum compound and a cobalt compound. The catalyst is further characterized as having a bimodal pore size distribution with a large portion of its total pore volume contained in pores having a diameter less than 250 angstroms and in pores having a diameter greater than 1000 angstroms.
US10563129B2 Use of cooling media in biomass conversion process
Biomass is converted into a bio-oil containing stream in a riser reactor containing a cooling media. The cooling media quenches the rapid heat transfer to the biomass during cracking of the biomass in the mixing zone of the riser. By lowering the temperature to which the mixing zone effluent is exposed, production of carbon monoxide and light gases is decreased during thermolysis of the biomass.
US10563126B2 Liquid crystal compound having benzothiophene, liquid crystal composition and liquid crystal display device
A liquid crystal compound is represented by formula (1): In formula (1), R1 is alkyl or the like; ring A1 and ring A2 are independently 1,4-cyclohexylene, 1,4-phenylene or the like; Z1, Z2 and Z3 are independently a single bond, —CF2O— or the like; X1 is fluorine, chlorine, —CF3 or the like; L1 and L2 are independently hydrogen, fluorine or the like; a and b are independently 0, 1, 2 or 3; and W is a group represented by formula (1a) or formula (1b); In formula (1a) and formula (1b), L3 to L8 are independently hydrogen, fluorine or the like.
US10563125B2 Stabilizer for thiol-ene compositions
The present invention relates to stabilizers for thiol-ene compositions and to radiation curable thiol-ene compositions based thereon. Such radiation curable compositions can advantageously be used in inks, overprint varnishes, coatings, adhesives, for the making of 3D objects and for the making of solder resist and gel nails. Provided in particular is an inhibitor system (I) for thiol-ene compositions based on —at least one inhibitor compound (i) having a % DPPH radical scavenging activity of at least 90%, the inhibitor compound (i) being selected from substituted benzene compounds or substituted naphthalene compounds containing at least two substituents selected from the group consisting of hydroxyl groups and C1-C3 alkoxy groups bonded directly to the benzene or the naphthalene ring, —at least one acidic compound (ii) having a pKa between 1 and 3, and —at least one compound (iii) selected from the group consisting of phosphites and phosphonites, with the proviso that if the inhibitor compound (i) is a substituted benzene that it contains at least two hydroxyl groups bonded directly to the benzene ring. Also provided is an inhibitor system (II) for thiol-ene compositions based on that is based on —at least one inhibitor compound (i) having a % DPPH radical scavenging activity of at least 90%, the inhibitor compound (i) being selected from substituted benzene compounds or substituted naphthalene compounds containing at least two substituents selected from the group consisting of hydroxyl groups and C1-C3 alkoxy groups bonded directly to the benzene or the naphthalene ring, —at least one compound (iv) selected from the group consisting of spirophosphites, and —optionally, at least one acidic compound (ii) having a pKa between 1 and 3, and with the proviso that if the inhibitor compound (i) is a substituted benzene that it contains at least two hydroxyl groups bonded directly to the benzene ring.
US10563124B2 Method of producing nitride fluorescent material
A method of producing a nitride fluorescent material having relatively high light emission intensity is provided. The method of producing a nitride fluorescent material includes preparing a calcined product having a composition containing at least one first element selected from the group consisting of Ba, Sr, Ca, and Mg, at least one second element selected from the group consisting of Eu, Ce, Tb, and Mn, and Si and N, and bringing the calcined product into contact with a fluorine-containing substance at a temperature in a range of −20° C. or higher and lower than 150° C.
US10563123B2 CuInS2/In2S3/ZnS fluorescent quantum dot with double-layer core-shell structure and preparation method thereof
The present invention provides a CuInS2/In2S3/ZnS fluorescent quantum dot with a double-layer core-shell structure, aiming to overcome the defects of the existing CuInS2 quantum dots. CuInS2 serves as a core, In2S3 serves as a first shell for cladding the core, and ZnS serves as a second shell for cladding the first shell. The present invention further provides a preparation method for the CuInS2/In2S3/ZnS fluorescent quantum dot with a double-layer core-shell structure. The CuInS2 quantum dot is synthesized using two stabilizers, and indium thiophosphate serves as a monomolecular precursor of the In2S3 shell.
US10563122B2 Semiconductor nanoparticles and method of producing semiconductor nanoparticles
A semiconductor nanoparticle includes a core and a shell covering a surface of the core. The shell has a larger bandgap energy than the core and is in heterojunction with the core. The semiconductor nanoparticle emits light when irradiated with light. The core is made of a semiconductor that contains M1, M2, and Z. M1 is at least one element selected from the group consisting of Ag, Cu, and Au. M2 is at least one element selected from the group consisting of Al, Ga, In and Tl. Z is at least one element selected from the group consisting of S, Se, and Te. The shell is made of a semiconductor that consists essentially of a Group 13 element and a Group 16 element.
US10563109B2 Additive for slurry, drilling mud, and cement slurry
Provided by the present invention is an additive for a slurry being capable of inhibiting viscosity elevation and dehydration at high temperatures at low cost, through use for a slurry for civil engineering and construction (for example, a drilling mud and a drilling cement slurry for use in well drilling. etc.), and the like. A powdery additive for a slurry, the powdery additive containing a vinyl alcohol polymer, which has: a solubility of 25% or less when immersed in hot water at 60° C. for 3 hours; a degree of saponification of at least 99.5 mol %; an average degree of polymerization of at least 1,500 and 4,500 or less; and the amount of 1,2-glycol linkage of 1.8 mol % or less, the powdery additive being capable of passing through a sieve having a nominal mesh opening size of 1.00 mm.
US10563107B2 Compositions comprising fluoroolefins and uses thereof
The present invention relates to fluoroolefin compositions. The fluoroolefin compositions of the present invention are useful as refrigerants or heat transfer fluids and in processes for producing cooling or heat. Additionally, the fluoroolefin compositions of the present invention may be used to replace currently used refrigerant or heat transfer fluid compositions that have higher global warming potential.
US10563099B2 Hot melt adhesive composition including a crystalline block composite
A hot melt adhesive composition includes (A) 20-95 wt % of a polymer component including an ethylene-based polymer and a propylene based polymer, the ethylene-based polymer being present in an amount greater than 30 wt %, based on a total weight of the polymer component, and (B) 1-60 wt % of a crystalline block composite comprising (1) a crystalline ethylene based polymer, (2) a crystalline alpha-olefin based polymer derived from at least one of a C3-10 α olefin, and (3) a block copolymer comprising 10-90 wt % of a crystalline ethylene block comprising 90 or more wt % units derived from ethylene and comprising 10-90 wt % of a crystalline alpha-olefin block comprising 90 or more wt % units derived from at least one of a C3-10 α olefin, (C) Optionally, from greater than zero to 70 wt % tackifier, and (D) Optionally, from greater than zero to 40 wt % of at least one selected from the group of a wax and an oil.
US10563098B2 Stabilization of hot melt adhesives
The present invention pertains to a stabilized hot melt adhesive containing a) one or more hot melt adhesive materials and b) a stabilizer composition. The one or more hot melt adhesive materials a) include a polyolefin, a styrene-isoprene-styrene block co-polymer, a styrene-butadiene-styrene block co-polymer, a polyacrylate, an acryl-copolymer, an ethylene vinyl acetate, a polyamide, a polyester, a polyurethane, a polyimide, a silane terminated polyolefin, a silane terminated poly-ether, and a silane terminated polyurethane. The stabilizer composition includes two or three of a component (A) which is a specific sterically hindered amine, a component (B) which is a polymeric sterically hindered amine, and a component (C) which is a specific sterically hindered phenol.
US10563095B2 Adhesive composition sheet, method of producing same, and semiconductor device
Provided is an adhesive composition sheet containing an organic compound and inorganic particles, the adhesive composition sheet including a structure obtained by stacking a layer A that contains at least an organic compound and a layer B that contains an organic compound and inorganic particles, the layer A having a content rate of the organic compound larger than the content rate of the organic compound in the layer B, and the layer A and/or the layer B containing anisotropically shaped inorganic particles. The present invention provides an adhesive composition sheet excellent in thermal conductivity and insulating properties after cured.
US10563093B2 Composition for forming dense siliceous film
[Object] To provide a polysilazane-containing composition for forming a film. In order to form a dense and processable siliceous film, the composition is intended to be employed in a two-step conversion process comprising the steps of: forming a film having a dry surface from the composition provided that the conversion in to the siliceous substance proceeds insufficiently; and then subjecting the film to secondary processing. [Means] The present invention provides a polysilazane-containing film-forming composition comprising a particular amine compound, a polysilazane compound, and a solvent; and the invention also provides a process for forming a siliceous substance. In the process, the composition is applied to coat a substrate and thereafter converted into the siliceous substance. The particular amine compound has two amine groups, and the amine groups have at least one phenyl-substituted hydrocarbon group.
US10563092B2 Composition for window film, flexible window film formed therefrom, and flexible display device comprising same
Provided are: a composition for a window film, containing a siloxane resin including chemical formula 1, a cross-linking agent, and an initiator; a flexible window film formed therefrom; and a flexible display device including the same.
US10563089B2 System for coatings for granular materials
A coating is applied in one or more layers on a granular material, such as a granular fertilizer material or the like. The coating may include a diisocyanate in either pure form or partially polymerized form, a polyol or polyol mix, and optionally a wax. The polyol or polyol mix may be, for example, a polyester polyol, a polyether polyol, or combinations thereof. In some examples, the polyol or polyol mix may be an aliphatic glycerine initiated polyether polyol, an aliphatic amine initiated trifunctional polyol, castor oil or castor oil derivative, or ethylene diamine that has been propoxylated or ethoxylated, and combinations thereof. The coating is reacted on the granular material.
US10563086B2 Solvent-based low temperature heat seal coating
A low temperature heat seal coating solution which contains an amorphous or semi-crystalline polyester or co-polyester resin, tackifier, anti-blocking agent, and solvent. The coating solution can be applied to a packaging web such as a foil or film by converters using conventional methods such as gravure, rod, slot die, or printing process. The heal seal coating can be sealed to itself or another substrate to manufacture food packaging bags or pharmaceutical blister packaging. The heat seal temperature can be as low as 70° C. under conventional equipment and conditions in the industry.
US10563078B2 Ink set and recording method using the same
An ink set includes a reaction liquid containing coagulant; a first ink containing a color material; and a second ink containing a color material. The ink set is used for recording on a non-absorptive recording medium or a low-absorptive recording medium and for imparting the reaction liquid, the first ink, and the second ink to the recording medium in a superimposed manner in this order.
US10563075B2 Actinic ray-curable-type inkjet ink composition for 3D printing, three-dimensional modeling method, and actinic ray-curable-type inkjet ink set for 3D printing
An actinic ray-curable-type inkjet ink composition for 3D printing includes an acrylate monomer A capable of forming a homopolymer having a glass transition temperature of from 25° C. to 120° C.; an acrylate monomer B capable of forming a homopolymer having a glass transition temperature of −60° or higher and lower than 25° C.; a bifunctional acrylate oligomer C having a weight-average molecular weight of from 2,000 to 20,000; and an acylphosphine oxide compound, in which the mass content of bifunctional or higher-functional acrylate compounds is 15% by mass or less.
US10563072B2 Deep base paint formulation
The present invention relates to a deep base paint composition comprising a binder (an aqueous dispersion of polymer particles), an associative thickener with a hydrophobic portion having a calculated log P in the range of from 2.7 to 4.8. The composition of the present invention provides a mechanism for decreasing the viscosity sensitivity of a base paint to colorant addition.
US10563071B2 Method for producing conductive polymer-containing dispersion
The present invention provides a method for producing a conductive polymer-containing dispersion, including: a polymerization step of polymerizing a monomer for obtaining a conjugated conductive polymer in a dispersion medium including the monomer and seed particles converted into a colloid protected by a polyanion.
US10563062B2 Polyarylene sulfide for oil and gas flowlines
Flowlines for use in oil and gas applications are described. The flowlines include a barrier layer that includes polyarylene sulfide composition that exhibits high strength and flexibility characteristics. Methods for forming the flowlines are also described. Formation methods include dynamic vulcanization of a polyarylene sulfide composition that includes an impact modifier dispersed throughout the polyarylene sulfide. A crosslinking agent is combined with the other components of the composition following dispersal of the impact modifier throughout the composition. The flowlines can include production fluid flowlines, supporting fluid flowlines, bundled flowlines, etc. and can be utilized as risers, pipelines, jumpers, and the like.
US10563061B2 Polymer blend and polymer agglomerate containing recycled multilayer film waste and fiber reinforced plastic waste and process for preparing said agglomerate
The invention relates to the recycling of polyamide and polyolefin wastes and fiber reinforced plastic wastes. Particularly, the invention relates to polymer blends and homogenous polymer agglomerates containing polyamide and polyolefin wastes or co-extruded film wastes and glass fiber reinforced plastic wastes, and to a single-stage continuous process for the preparation of said agglomerate. The invention also relates to products containing the aforementioned substances.
US10563057B2 Poly(vinyl acetal) resin compositions, layers, and interlayers having enhanced optical properties
Resin compositions, layers, and interlayers comprising two or more thermoplastic polymers and at least one RI balancing agent for adjusting the refractive index of at least one of the resins or layers is provided. Such compositions, layers, and interlayers exhibit enhanced optical properties while retaining other properties, such as impact resistance and acoustic performance.
US10563056B2 Expandable thermoplastic resin particles, thermoplastic pre-expanded particles, and thermoplastic expansion-molded article
An expandable thermoplastic resin particle including a polymer obtained by a process including polymerizing monomers including 60 to 80 parts by weight of α-methylstyrene and 40 to 20 parts by weight of acrylonitrile. A content of residual monomeric components in the expandable thermoplastic resin particle is not more than 0.5% by weight. When an expanded mold article is produced from the expandable thermoplastic resin particle at an expansion ratio of 10 times, foam cells in a cross section of the expanded mold article have an average chord length of from 20 μm to 60 μm.
US10563052B2 Bioplastic composition comprising wheat bran and bioplastic film using the same
The present invention relates to a bioplastic composition comprising wheat bran that is a food byproduct and a bioplastic pellet/film using the same. More particularly, the present invention relates to a bioplastic composition comprising wheat bran and a bioplastic film using the same in which the properties of the composition are enhanced to secure the improved properties of the bioplastic film prepared from it, thereby showing a carbon reduction effect and providing a substitute for the conventional petroleum-derived bioplastic products.
US10563050B2 Pneumatic tire
The present invention is directed to a pneumatic tire having a tread comprising a vulcanizable rubber composition comprising, based on 100 parts by weight of elastomer (phr), (A) from about 60 to about 100 phr of a solution polymerized styrene-butadiene rubber having more than 98 percent of the repeat units derived from styrene in blocks containing less than five repeat units, Tg ranging from −65° C. to −79° C.; (B) up to 40 phr of polybutadiene having a cis 1,4 content greater than 95 percent and a Tg ranging from −80 to −110° C.; (C) from 30 to 80 phr of a combination of a resin having a Tg of at least 30° C. and an oil, wherein the weight ratio of resin to oil is greater than 1.
US10563040B2 Low-temperature curable compositions
This invention pertains to a curable composition comprising a first component having beta-ketoacetate and/or malonate functionalities and a second component having two or more aldehyde functionalities. The compositions can be cured at room temperature or low temperatures to yield crosslinked networks that are capable of providing desirable properties for coating and adhesive applications. The reactive functionalities of beta-ketoacetate, malonate, and aldehyde can be either on polymers as the main binders or on small molecules as the crosslinkers. The curable compositions desirably are either solventless or organic solvent based.
US10563036B2 Method of establishing predetermined viscosities when recycling polyester waste
The aim is to refine a method of establishing a predetermined viscosity when recycling polyester wastes having inherently different viscosities in such a way that the desired final material has the appropriate viscosity after a fairly short time, and with little energy consumption, and the color of the melt is also to be influenceable. To this end, it is proposed that the polyester wastes are melted in a first zone (9) of an extruder (1) and the polyester wastes, due to the moisture introduced with them, undergo hydrolytic degradation, in a second zone (11) of the extruder (1) polycondensation takes place and hydrolytic degradation is counteracted and equalization of the viscosity differences is started, in a third zone (13) of the extruder (1) a solvent such as water or alcohol is added such that hydrolytic and/or glycolytic degradation of the melt take(s) place and result(s) in uniform viscosity of the melt, in a fourth zone (14) of the extruder (1) active mixing of the melt takes place and the melt is transferred from the extruder (1) into a polycondensation reactor (6), and the final desired viscosity of the melt is set in the polycondensation reactor (6).
US10563033B2 Foam insulation with enhanced fire and smoke performance
A polyisocyanurate foam insulation product includes polyisocyanurate foam produced from reacting an isocyanate and a polyol blend having a functionality of at least 2.2. The isocyanate and the polyol blend are reacted so that the polyisocyanurate foam has an isocyanate index equivalent with or greater than 300. The polyisocyanurate foam includes a fire retardant and includes between 0.02 and 0.45 weight percent of a zinc salt compound. The foam insulation board exhibits a flame spread of no greater than 25 and a smoke index of no greater than 50 when exposed to flame conditions in accordance with an ASTM E-84 test.
US10563029B2 Resin composition and prepreg, resin sheet, laminate, and printed circuit board
A resin composition containing a compound represented by the following general formula (a) or the following general formula (b), an alkenyl-substituted nadimide compound, and a maleimide compound: wherein Ra represents a group represented by the following general formula (c),
US10563028B2 Films and membranes of poly(aryl ketones) and methods of casting the same from solution
A method of manufacturing a film or membrane includes: (a) dissolving at least one polymer comprising a poly(aryl ketone) in at least one solvent to form a dope; (b) depositing the dope on a substrate to form a coated substrate at appropriate conditions; and (c) drying the coated substrate to form the film or membrane. The dope may also include additional polymers or fillers, such as carbon nanotubes.
US10563023B2 Carbon fiber composite, a medium incorporating the carbon fiber composite, and a related method
Carbon fiber composite additives, media incorporating the carbon fiber composites, and related methods are provided herein. In some aspects, a composition includes at least one medium; and a carbon fiber composite incorporated with the at least one medium, the carbon fiber composite including one or more carbon fibers with an epoxy resin matrix applied thereto to produce a composition having improved characteristics and filtration performance.
US10563022B2 Hydroxyl-terminated PDMS as cure control additive for the silane crosslinking of polyolefins
Scorch of a silane-functionalized polyolefin is minimized during melt mixing with a flame retardant through the use of a polydimethylsiloxane (PDMS) having a (1) number average molecular weight (Mn) greater than or equal to (≥) 4,000 grams per mole (g/mol), (2) viscosity of greater than or equal to (≥) 90 centipoise (cP), and (3) hydroxyl group content of less than or equal to (≤) 0.9 weight percent (wt %) based on the weight of the PDMS.
US10563012B2 Biodegradable side chain liquid crystal elastomers: smart responsive scaffolds (SRS) for tissue regeneration
Controlled biodegradable smart responsive scaffold (SRS) materials enhance attachment and viability of cells, i.e. actively guiding their expansion, proliferation and in some cases differentiation, while increasing their biomechanical functionality is an important key issue for tissue regeneration. Chemically build-in functionality in these biodegradable SRS materials is achieved by varying structural functionalization with biocompatible liquid crystal motifs and general polymer composition allowing for regulation and alteration of tensile strength, surface ordering, bioadhesion and biodegradability, bulk liquid crystal phase behavior, porosity, and cell response to external stimuli. Liquid crystal modification of such polymeric scaffolds is an ideal tool to induce macroscopic ordering events through external stimuli. None of these approaches have been demonstrated in prior art, and the use of biocompatible scaffolds that respond to a variety of external stimuli resulting in a macroscopic ordering event is a novel aspect of the present invention.
US10563009B2 Process to produce a polyolefin reactive telechelic pre-polymer
A process to produce a polyolefin reactive telechelic pre-polymer comprising reacting alkyl-cis-cyclooctene, and optionally cis-cyclooctene, in the presence of a multifunctional chain transfer agent possessing two or more amino groups wherein the two or more amino groups are protected by one or more protecting groups under ring opening metathesis polymerization conditions to form a dicarbamate telechelic unsaturated polyolefin pre-polymer is provided.
US10563007B2 Impregnating resin, conductor arrangement, electrical coil and electrical machine
An impregnating resin, e.g., a catalytically hardenable impregnating resin for the conductor of an electrical machine, may include at least one reactive resin mixed with at least one reactive diluent and a hardening catalyst, e.g., for cationic, anionic or coordinate polymerization of the impregnating resin. The properties of the impregnating resin or use thereof may be improved by virtue of the reactive diluent containing a heterocyclic four-membered ring. The impregnating resin may be part of a main insulation of a conductor arrangement, which may in turn be installed in an electrical coil or other electrical machine.
US10563006B2 Resin composition, and prepreg, metal-clad laminate, and printed circuit board prepared using the same
A resin composition is provided. The resin composition comprises an epoxy resin (A) and a first hardener (B) of the following formula (I): wherein Ar, R and n are as defined in the specification, and the molar ratio of the epoxy group of the epoxy resin to the active functional group of the first hardener ranges from about 1:0.4 to about 1:1.6.
US10563002B2 Methods and product for forming lines utilizing liquid acrylic copolymer solution
A liquid water-based solution for application of temporary floor markings on a polyurethane coated floor and a method of applying the same is disclosed. According to one aspect, the solution comprises 5-15% by weight of an acrylic copolymer, 1%-2% propylene glycol, 0.5%-2% dipropylene glycol mono-methyl-ether, 2-8% of titanium dioxide; and 1-5% of ethelyne glycol. The solution is dispensable through a foam applicator so that it can be used to form temporary lines for recreational and athletic activities. The solution has a drying time when applied to the polyurethane floor of under five minutes and can remains water soluble for an extended period of time so that it can be removed without damaging the underlying surface.
US10563000B2 Low-temperature radical polymerisation of alkoxyamines
The present invention relates to a process for the radical polymerization of alkoxyamines at low temperature, typically at temperatures as low as −50° C., in the presence of a nitroxide reducing agent or photoinitiator.
US10562999B2 Copolymers having phosphorus group-carrying monomeric units
A copolymer, in particular a dispersant for solid particles, in particular a dispersant for mineral binder compositions, including a polymer backbone and sidechains bound thereto. Said copolymer includes at least one phosphorus group-carrying monomeric unit M1 and at least one sidechain-carrying monomeric unit M2, the copolymer having, in a direction along the polymer backbone, a non-random distribution of the monomeric units M1 and/or of the monomeric units M2.
US10562994B2 Polyolefin for preparing fiber and fiber comprising the same
The present invention relates to polyolefin powder for preparing fiber, and fiber comprising the same. According to the present invention, provided is polyolefin, which exhibits a high molecular weight range and narrow molecular weight distribution and in which the formation of a gel deteriorating the quality of fiber is reduced. Therefore, by using the polyolefin, the present invention exhibits molecular weight, density and narrow molecular weight distribution, which are equivalent to those of conventional polyolefin, but the number of gels having a large particle diameter is remarkably reduced, and therefore, the present invention can provide fiber having excellent tenacity and tensile strength half-life.
US10562993B2 Polymer composition and optical material
Provided is a polymer composition, wherein the polymer composition has a refractive index difference (B−A) of 0.04 or greater but 0.1 or less between a minimum refractive index A of the polymer composition in a temperature range of 5 degrees C. or higher but lower than 30 degrees C. and a maximum refractive index B of the polymer composition in a temperature range of 30 degrees C. or higher but lower than 50 degrees C.
US10562990B2 Catalyst for the polymerization of olefins
A catalyst for the homopolymerization or copolymerization of CH2═CHR olefins, made from or containing the product obtained by contacting: (i) a solid catalyst component made from or containing Ti, Mg, Cl, and an internal electron donor compound, wherein the solid catalyst component contains from about 0.1 to about 50 wt % of Bi, based upon the total weight of the solid catalyst component; (ii) an alkyl aluminum compound and, (iii) an external electron donor compound having the formula: (R1)aSi(OR2)b wherein R1 and R2 are independently selected from the group consisting of alkyl radicals with 1-8 carbon atoms and a is 0 or 1 and a+b=4.
US10562987B2 Polymers produced via use of quinolinyldiamido transition metal complexes and vinyl transfer agents
Catalyst systems with single site transition metal complexes (such as quinolinyldiamide transition metal complexes), an activator, and a metal hydrocarbenyl transfer agent (preferably an aluminum vinyl-transfer agent) are disclosed for use in alkene polymerization.
US10562983B2 Method for preparing hydroxypropyl methylcellulose acetate succinate (HPMCAS) grains having controlled grain size distribution, and HPMCAS powder
Disclosed are a method for preparing hydroxypropyl methylcellulose acetate succinate (HPMCAS) grains and HPMCAS grains. The disclosed method for preparing HPMCAS grains comprises: a step of esterifying hydroxypropyl methylcellulose (HPMC), acetic anhydride, and succinic anhydride in a reaction medium in the presence of a catalyst so as to obtain a reaction solution containing HPMCAS (esterification step); and a step of continuously or intermittently putting the reaction solution into water so as to form grains (granulating step).
US10562980B2 Humanized antibodies
The present disclosure provides humanized antibodies, including antibodies comprising an ultralong CDR3 and uses thereof.
US10562979B1 Hybridoma cell line of secreting meloxicam monoclonal antibodies and application thereof
A hybridoma cell line of secreting meloxicam monoclonal antibodies with a preservation number of hybridoma cell line of CGMCC No. 14700 belongs to the field of food safety immunological detection. The. BALB/c mice are immunized through one time immunization with complete freund's adjuvant, three times of booster immunization with incomplete freund's adjuvant and one time of rush immunization with meroxicam complete antigen without adjuvant; the spleen cells from BALB/C mice immunized with high potency and low value of IC50 are fused with murine myeloma cells; and then the hybridoma cell line is obtained through indirect competitive ELISA screening and three sub-clones. The monoclonal antibody secreted by this cell line has good specificity and detection sensitivity to meloxicam (value of IC50 is 0.1 ng/ml), being suitable for detection of meroxicam in food.
US10562978B2 Methods using antibodies specific for 4,6-diamino-5-(formamido)pyrimidine
The invention includes monoclonal and polyclonal antibodies, and antigen-binding fragments thereof, having specific binding affinity for 4,6-diamino-5-(formylamino)pyrimidine (FAPY-adenine); hybridomas producing such antibodies; immunoconjugates comprising an antibody or antigen-binding fragment of the invention coupled to a moiety; and in vitro and in vivo methods for using such antibodies, antibody fragments, and conjugates based on binding to FAPY-adenine; nucleic acids encoding the heavy and/or light chains of the antibodies; vectors comprising the nucleic acid sequences encoding the heavy and/or light chains; host cells comprising and, optionally, expressing the nucleic acid sequences; and methods for the production of the aforementioned materials.
US10562972B2 Antibodies targeting B-cell maturation antigen and methods of use
The presently disclosed subject matter provides antibodies that bind to B-cell maturation antigen (BCMA) and methods of using the same.
US10562970B2 Antibodies that bind colony stimulating factor 1 receptor (CSF1R)
Antibodies that bind CSF1R are provided. Antibody heavy chains and light chains that are capable of forming antibodies that bind CSF1R are also provided. Polynucleotides encoding antibodies to CSF1R are provided. Polynucleotides encoding antibody heavy chains and lights chains are also provided. Methods of treatment using antibodies to CSF1R are provided. Such methods include, but are not limited to, methods of treating rheumatoid arthritis, bone loss, and multiple sclerosis.
US10562968B2 Anti-GPRC5D antibodies, bispecific antigen binding molecules that bind GPRC5D and CD3, and uses thereof
Provided herein are antibodies that specifically bind to GPRC5D. Also described are related polynucleotides capable of encoding the provided GPRC5D-specific antibodies or antigen-binding fragments, cells expressing the provided antibodies or antigen-binding fragments, as well as associated vectors and detectably labeled antibodies or antigen-binding fragments. In addition, methods of using the provided antibodies are described. For example, the provided antibodies may be used to diagnose, treat, or monitor GPRC5D-expressing cancer progression, regression, or stability; to determine whether or not a patient should be treated for cancer; or to determine whether or not a subject is afflicted with GPRC5D-expressing cancer and thus may be amenable to treatment with a GPRC5D-specific anti-cancer therapeutic, such as the multispecific antibodies against GPRC5D and CD3 described herein.
US10562964B2 Methods for isolating antibodies that bind sclerostin
Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
US10562962B2 Antibodies specific for hyperphosphorylated tau and methods of use thereof
The present invention relates to a novel class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396), as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and tauopathies.
US10562960B2 Neutralizing antibodies to gp120 and their use
Antibodies and antigen binding fragments that specifically bind to gp120 and neutralize HIV-1 are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed.
US10562959B2 Lactoferrin fusion protein and method for preparation thereof
The present invention aims to provide a lactoferrin fusion protein, which is configured to retain the biological activities of natural lactoferrin, to have a significantly prolonged in vivo lifetime, and to be more clinically useful than natural and gene recombinant lactoferrin, as well as a method for preparation thereof, etc. The present invention provides a fusion protein formed with a protein or peptide comprising an FcRn-binding region and lactoferrin or a biologically active fragment or peptide of lactoferrin, which is represented by: (LF-s-Y)n or(Y-s-LF)n [wherein LF represents lactoferrin or a biologically active fragment or peptide of lactoferrin, Y represents the protein or peptide comprising an FcRn-binding region, s represents any amino acid sequence of 0 to 10 residues, and n represents an integer of 1 to 10], or a variant thereof.
US10562956B2 Recombinant fibrinogen
The present invention relates to nucleotide sequences encoding a fibrinogen alpha, beta or gamma chain. The sequences are optimized for expression in a eukaryotic cell culture system. Such optimized nucleotide sequences allow for the efficient expression of recombinant fibrinogen and variants thereof in intact form in a eukaryotic cell culture system.
US10562945B2 Specific active site inhibitors of enzymes or substrate binding partners and methods of producing same
The present disclosure provides a method of producing enzyme-specific inhibitors or substrate binding partners comprising: identifying active site residues of the substrate in the enzyme substrate complex or in substrate binding partner-substrate complex; randomizing the active site residues to produce a combinatorial library of substrate variants; and selecting substrate variants that inhibit enzyme activity or bind substrate as substrate-specific binding partners. The present disclosure also provides ubiquitin enzyme specific inhibitors and ubiquitin variants that bind ubiquitin interaction motifs.
US10562942B2 Cotton variety 16R023
The invention relates to the novel cotton variety designated 16R023. Provided by the invention are the seeds, plants, plant parts and derivatives of the cotton variety 16R023. Also provided by the invention are methods of using cotton variety 16R023 and products derived therefrom. Still further provided by the invention are methods for producing cotton plants by crossing the cotton variety 16R023 with itself or another cotton variety and plants and seeds produced by such methods.
US10562940B2 Computationally optimized broadly reactive antigens for H1N1 influenza
Described herein is the generation of optimized H1N1 influenza HA polypeptides for eliciting a broadly reactive immune response to H1N1 influenza virus isolates. The optimized HA polypeptides were developed through a series of HA protein alignments, and subsequent generation of consensus sequences, based on selected H1N1 viruses isolated from 1918-2011. Provided herein are optimized H1N1 HA polypeptides, and compositions, fusion proteins and VLPs comprising the HA polypeptides. Further provided are codon-optimized nucleic acid sequences encoding the HA polypeptides. Methods of eliciting an immune response against influenza virus in a subject are also provided by the present disclosure.
US10562937B2 Electron spin labeled ice binding compounds used for carrying paramagnetic centers for dynamic nuclear polarization
Spin-labeled ice binding compounds (IBCs) including ice binding proteins (IBPs) or antifreeze proteins (AFPs) and their analogs may carry paramagnetic centers for dynamic nuclear polarization (DNP), for enhancing nuclear magnetic resonance (NMR) signal intensities. Use of spin-labeled IBCs to perform DNP exploits the IBCs' ability to homogeneously distribute the paramagnetic centers in frozen water solution at low temperature, leading to high DNP efficiency. Other advantages of using spin-labeled IBCs include cryo-protecting biological samples; cryo-preserving relative positions and orientations of the spin labeling groups; selecting positions and orientations of spin labeling groups with freedom and without technical barriers to making multiple spin labels in an IBC; and enabling use of a solvent that is primarily water for DNP at low temperatures in view of the potentially high water solubilities of spin-labeled IBCs.
US10562935B2 Stapled peptides and uses thereof
Cyclized peptides derived from the hyaluronan binding region of RHAMM are provided. Pharmaceutical compositions and methods for using the peptides and pharmaceutical compositions are also provided. The peptides and pharmaceutical compositions can be used for the treatment of cancer, inflammatory disorders, autoimmune disorders, and fibrotic disorders.
US10562931B2 Process for the preparation of (1S, 4S, 7Z, 10S, 16E, 21R)-7-ethyldene-4,21-bis(1-methyl-ethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3, 6, 9, 19, 22-pentone
The present invention is relates to an improved process for the preparation (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(1-methylethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabi-cyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone of formula I.
US10562926B2 Guanine analogs as telomerase substrates and telomere length affectors
This invention relates to compounds useful for inhibiting telomere elongation. More specifically, the invention provides nucleotide analogs that are incorporated into telomeres by telomerase thereby inhibiting elongation of telomeres. The compounds are use in treating cancer and other cell proliferative diseases.
US10562922B2 Silicon based cyclic compounds and pharmaceutical compositions for treating malaria and toxoplasmosis
The present invention discloses novel silicon incorporated cyclic compounds of formula I, Wherein Ar1 and Ar2 are individually selected from any aryl group which can be optionally substituted; X is selected from any inorganic anion such as halide, carbonate, sulfate, nitrate or any organic anion selected from acetate, tartarate, citrate, carbonate or organosulfonates such as tosylate, mesylate, triflate; R1 and R2 are individually selected from C1-C8 alkyl, cycloalkyl, aryl, heteroaryl, aralkyl, alkoxyalkyl, aminoalkyl, thioalkyl, haloalkyl or hydroxyalkyl. R1 and R2 together may form a ring which optionally may be substituted or may contain heteroatoms; a pharmaceutical composition comprising a therapeutically effective amount of compounds of general formula I, including geometrical isomers and/or salts thereof along with a drug and optionally along with a carrier or diluent or pharmaceutically acceptable excipient for treating malaria and toxoplasmosis.
US10562921B2 Oxaborole esters and uses thereof
The present invention provides oxaborole ester compounds and compositions thereof which are useful to treat diseases associated with parasites, such as Chagas Disease and African Animal Trypanosomosis.
US10562916B2 Substituted quinoxalines as PDE-10 inhibitors
Provided herein are cyclic nucleotide phosphodiesterase inhibitors, and pharmaceutical compositions thereof, useful for the treatment of, for example, central nervous system and metabolic diseases and disorder.
US10562914B2 Imidazoles as histone demethylase inhibitors
The present invention relates to imidazole derivatives of Formula (I), wherein A, R, R1, and R2 are as defined in the specification, pharmaceutical compositions containing such compounds and to their use in therapy.
US10562913B2 Indolizine-based dyes for dye-sensitized solar cell
Compounds for use as sensitizer dyes in dye-sensitized solar cells.
US10562911B2 Method for isolating flavonoids from rice plant inoculated with whitebacked planthopper
The present invention relates to a method for isolating flavonoids such as cochlioquinone or chrysoeriol from a rice plant inoculated with a whitebacked planthopper. The method of the present invention, for example, facilitates not only the fast production of flavonoids such as cochlioquinone or chrysoeriol but also the mass-production of flavonoids such as cochlioquinone or chrysoeriol with high efficiency in addition to the advantage of saving costs. Therefore the method of the present invention can be effectively used for the production of flavonoids such as cochlioquinone or chrysoeriol and also be used in various fields using the same.
US10562906B2 TYK2 inhibitors and uses thereof
The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
US10562904B2 Synthesis process of ruxolitinib
The present application falls within the field of drug synthesis, and in particular, the present application relates to a method for preparing ruxolitinib, and a method for preparing the intermediate and relevant intermediates used. The method comprises reacting a compound of formula II with a compound of formula IV or a salt thereof to obtain a compound of formula III, and then subjecting the compound of formula III to an acyl halogenation reaction, an amidation reaction, and a reaction dehydrating an amide to form a cyano group or removing the protecting group to prepare ruxolitinib. The method has the characteristics of brief steps, a high stereoselectivity, a high utilization ratio of atoms, mild reaction conditions and convenient post treatment. The method avoids using expensive asymmetric reaction catalysts, and is suitable for industrial production.
US10562901B2 Temozolomide compounds, polymers prepared therefrom, and method of treating a disease
A temozolomide compound according to formula (I) is described, wherein R1, L1, and X are defined herein. The temozolomide compound can be used to prepare polymers comprising temozolomide. Additionally, the polymers comprising temozolomide can be particularly useful in the treatment of certain diseases.
US10562893B2 Benzimidazoles derivatives as Tec kinases family inhibitors
The present invention relates to a novel family of covalent kinases inhibitors. Compounds of this class have been found to have inhibitory activity against members of the Tec kinase family, particularly ITK, BTK, BMX, Tec and/or RLK. The present invention is directed to a compound of Formula I or pharmaceutically acceptable salt, solvate, solvate of salt, stereoisomer, tautomer, isotope, prodrug, complex or biologically active metabolite thereof and its use in therapy.
US10562887B2 Triazolones and tetrazolones as inhibitors of ROCK
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
US10562886B2 Anti-cancer compounds
This invention provides, among other things, compounds useful for treating diseases such as cancer, pharmaceutical formulations containing such compounds, as well as combinations of these compounds with at least one additional therapeutic agent.
US10562885B2 Method for producing triazole compound
A compound represented by formula (5) can be produced by simultaneously and separately adding a compound represented by formula (4) and methanesulfonyl chloride to a compound represented by formula (3) and a compound represented by formula (6) having excellent control efficacies against pests can be produced by subjecting the compound represented by formula (5) to intramolecular condensation in the presence of an acid.
US10562883B2 Heterocycles capable of modulating T-cell responses, and methods of using same
The present disclosure is directed in part to heterocycles, and their use in treating medical disorders, such as immune inflammatory disorders such as Crohn's disease, ulcerative colitis, rheumatic disorders, psoriasis, and allergies. The compounds are contemplated to modulate T-Cell responses.
US10562881B2 Method for producing heterocyclic compound
The present invention provides a production method of heterocyclic compound having an excellent CH24H inhibitory action, which is suitable for industrial production.In the present invention, a 2-halogenonicotinic acid or a reactive derivative thereof or a salt thereof is reacted with 4-benzyl-4-hydroxypiperidine acid addition salt to give a (4-benzyl-4-hydroxypiperidin-1-yl) (2-halogenopyridin-3-yl)methanone or a salt thereof, and then the obtained compound is reacted with pyridine-4-boronic acid or a reactive derivative thereof or a salt thereof in the presence of a metal catalyst and a base to give (4-benzyl-4-hydroxypiperidin-1-yl) (2,4′-bipyridin-3-yl)methanone or a salt thereof.
US10562879B2 Method for preparing thienyl alanine having optical activity
This invention relates to a method of preparing optically active β-2-thienyl-alanine, and more particularly to a method of preparing optically active β-2-thienyl-L-alanine or optically active β-2-thienyl-D-alanine through an optical resolution reaction using chiral dibenzoyl tartaric acid or a derivative thereof as an optical resolving agent.
US10562878B2 Cycloalkylamines as monoamine reuptake inhibitors
The invention relates to novel cyclohexylamine derivatives and their use in the treatment and/or prevention of central nervous system (CNS) disorders, such as depression, anxiety, schizophrenia and sleep disorder as well as methods for their synthesis. The invention also relates to pharmaceutical compositions containing the compounds of the invention, as well as methods of inhibiting reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine from the synaptic cleft and methods of modulating one or more monoamine transporter.
US10562876B2 Organic compounds for organic light-emitting diode and organic light-emitting diode including the same
The present invention relates to a compound for organic light-emitting diodes that can operate organic light-emitting diodes at a low driving voltage and an organic light-emitting diode comprising the same and, more particularly, to a compound for use as a fluorescent host in organic light-emitting diodes, which can bring about excellent diode properties by operating organic light-emitting diodes at a low driving voltage, and an organic light-emitting diode comprising the same.
US10562875B2 Aromatic compounds from furanics
Described are methods for preparing phenols, benzene carboxylic acids, esters and anhydrides thereof from furanic compounds by reaction with a dienophile, wherein the furanic compounds are reacted with a hydrazine and/or oxime and then reacted with a dienophile.
US10562874B2 Process for the recovery of furfural
A process for the extraction of furfural from a composition comprising furfural, water, at least one organic acid and an oxygenate solvent with a boiling point higher than that of furfural. The process includes: (a) subjecting the composition to a first liquid-liquid separation step to provide: (i) an organic phase; (b) subjecting the organic phase of step (a) to a first distillation step to provide: (i) a first top stream; (c) subjecting the first top stream of step (b) to a second liquid-liquid separation step to provide: (i) a second top stream; and (d) subjecting the second top stream of step (c) to a second distillation step to provide: (i) a third top stream comprising a furfural-water azeotrope, and (ii) a third bottom stream comprising furfural.
US10562873B1 Methods of producing glycidyl nitrate
Methods of producing glycidyl nitrate. The method comprises reacting glycerol and nitric acid in a microfluidic reactor to form a nitrated glycerol compound. The microfluidic reactor comprises a reaction volume of the microfluidic reactor of less than about 20 ml and an inner diameter of a reaction channel of the microfluidic reactor of less than or equal to about 1000 μm. The nitrated glycerol compound is reacted with a base in the microfluidic reactor to form glycidyl nitrate. Additional methods of producing glycidyl nitrate are also disclosed.
US10562870B2 Prodrugs of riluzole and their method of use
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process.
US10562867B2 Process for the preparation of a dual-acting angiotensin receptor-neprilysin inhibitor compound
The present invention relates to a process for preparing amorphous form of Sacubitril/Valsartan sodium salt of Formula-II and pharmaceutical composition comprising thereof.
US10562866B2 Amorphous trisodium sacubitril valsartan and a process for the preparation thereof
The amorphous form of trisodium sacubitril valsartan and methods for the preparation thereof are disclosed herein.
US10562865B2 Aryl or heteroaryl triazolone derivatives or salts thereof, or pharmaceutical compositions comprising the same
The present technology provides aryl or heteroaryl triazolone derivatives or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and the use thereof. The aryl or heteroaryl triazolone derivatives or their pharmaceutically acceptable salts exhibit selective inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).
US10562864B2 Chemical modulators of immune checkpoints and therapeutic use
Compounds and pharmaceutical compositions that down-regulate immune checkpoints such as PD-1, PD-L1 and CTLA-4 are provided. Also provided are methods of treating a disease by down-regulating immune checkpoints such as PD-1, PD-L1 and CTLA-4. The methods are useful for treating cancer and viral infection in a subject.
US10562860B2 Hydantoin containing deoxyuridine triphosphatase inhibitors
Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
US10562859B2 Aryl sulfonamide compounds as carbonic anhydrase inhibitors and their therapeutic use
Disclosed herein are compounds having the following structure useful as inhibitors of carbonic anhydrase IX (CAIX) and XII, and particularly useful for reducing or eliminating metastases see Formula (I).
US10562854B2 Prolyl hydroxylase inhibitors
Disclosed herein are prolyl hydroxylase inhibitors that can stabilize hypoxia inducible factor-1 alpha (HIF-1α), as well as hypoxia inducible factor-2 (HIF-2). Also disclosed herein are pharmaceutical compositions comprising one or more of the disclosed compounds. Yet further disclosed are methods for stimulating the cellular immune response in a mammal such as increasing phagocytosis, for example, prolonging the life of phagocytes, inter alia, kerotyiocytes, neutrophils. As such the disclosed compounds provide methods for treating diseases that relate to the body's immune response.
US10562853B2 Compounds for treating disorders sensitive to serotoninergic regulation controlled by the 5-HT1A receptors
The invention concerns compounds that possess a high affinity at 5-HT1A receptors and an agonist efficacy, as measured by Emax values from a cellular activation assay, that is higher than that of the compounds described in prior art. The capacity of the compounds of the invention to activate an effector protein complex is higher than that the most efficacious agonist described in prior art. Compounds of the invention also exhibit an exceptionally high selectivity (Ki ratio greater than 1000-fold) with respect, in particular, to dopamine D2 receptors and adrenergic receptors of the alpha1 subtype. This selectivity which constitutes a great advantage since it means that the compounds will avoid inducing (central and peripheral) effects associated with activating or inhibiting such receptors.
US10562852B2 Crystalline forms of (R)-1-(1-(methylsulfonyl)propan-2-yl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile
This invention relates to crystalline forms of (R)-1-(1-(methylsulfonyl)propan-2-yl)-4-(trifluoromethyl)indoline-5-carbonitrile, a modulator of the androgen receptor, and methods for the use in treatment.
US10562848B2 Inhibitors of TNF superfamily costimulatory interactions and methods for uses of the same
Disclosed herein are inhibitors of TNF superfamily costimulatory interactions, and methods for their use in modulating TNF superfamily costimulatory interactions and treating immune system related disorders. In particular, disclosed herein are compounds of Formula (I), and pharmaceutically acceptable salts thereof: wherein the substituents are described herein.
US10562847B2 Method for preparation of isosulfan blue
Provided is a method of preparing isosulfan blue.
US10562843B2 Preparation of (R,R)-fenoterol and (R,R)- or (R,S)-fenoterol analogues and their use in treating congestive heart failure
This disclosure concerns the discovery of (R,R)- and (R,S)-fenoterol analogues which are highly effective at binding β2-adrenergic receptors. Exemplary chemical structures for these analogues are provided. Also provided are pharmaceutical compositions including the disclosed (R,R)-fenoterol and fenoterol analogues, and methods of using such compounds and compositions for the treatment of cardiac disorders such as congestive heart failure and pulmonary disorders such as asthma or chronic obstructive pulmonary disease.
US10562834B2 Process for preparing substituted crotonic acids
A process to prepare a compound of Formula (I) wherein R3, R4 and R5 are each selected independently from hydrogen, halogen, alkyl, alkenyl, alkynyl, alkoxyl, and wherein the alkyl, alkenyl, alkynyl, and alkoxyl may be optionally substituted with one or more halogen, alkyl, alkenyl, alkynyl, and alkoxyl.
US10562829B1 Highly selective olefin removal with unsulfided hydrotreating catalysts
A process is disclosed for polishing a relatively highly pure stream of aromatic material bound for use as a petrochemical feedstock wherein the stream includes olefins and especially concerning, diolefins. The process comprises hydrotreating the highly pure aromatic stream with an unsulfided cobalt molybdenum catalyst that has low saturating activity for the aromatic but is active for saturating olefins and diolefins.
US10562828B2 Stabilized DCD and/or alkyl thiophosphoric triamide solvent systems and use in agricultural applications
An inhibitor composition contains alkyl thiophosphoric triamide (or a mixture of alkyl thiophosphoric triamide and dicyandiamide),dissolved in a liquid medium including at least one organic solvent, at least one amine stabilizer and, optionally, at least one dye and/or at least one odor masking agent, is useful in making fertilizer compositions and in a method of fertilizing target plants.
US10562818B2 Insulator composition and manufacturing method using the same
An insulator composition includes Al2O3 having a particle size of 120 to 500 nm. The insulator composition has a strength of 400 to 740 MPa and a particle size of 1 μm or less.
US10562806B2 Ion exchangeable glass with high crack initiation threshold
Alkali aluminosilicate glasses that are resistant to damage due to sharp impact and capable of fast ion exchange are provided. The glasses comprise at least 4 mol % P2O5 and, when ion exchanged, have a Vickers indentation crack initiation load of at least about 7 kgf.
US10562803B2 Tool for a glass-bending process
A tool for holding at least one glass pane by means of suction in a bending process, comprising a frame-like, convex contact surface and a cover having a peripheral air guide plate that surrounds the contact surface at least in regions is described. The tool is suitable for generating a first, reduced pressure in a first pressure region between the air guide plate and the contact surface; a second pressure in a second pressure region, which is arranged in a central region inside the contact surface, wherein the second pressure is greater than the first pressure.
US10562801B2 Redox water treatment method
A redox water treatment method comprises first determining the composition of water and whether water treatment requires either oxidation or reduction, or both to optimize nitrogen removal by a bioreactor. Sulfur dioxide (SO2) is injected into the water to be treated to provide H+, SO2, SO3=, HSO3−, dithionous acid (H2S2O4), and other sulfur intermediate reduction products forming a sulfur dioxide treated water, which behaves either as a reducing agent or an oxidizing agent depending on the strength of the acid concentration, which alters sulfurous acid from a reducing agent to a more powerful oxidizing agent.
US10562800B2 Method for processing fluorine-containing aqueous solution
The present disclosure provides a method for processing a fluorine-containing aqueous solution. The method comprises a reaction step for mixing in a vertical direction the fluorine-containing aqueous solution and a disiloxane compound represented by a general formula RaRbRcSiOSiRdReRf, wherein Ra, Rb, Rc, Rd, Re and Rf are selected independently from each other from a group consisting of a phenyl group and an alkyl group comprising from 1 to 20 carbon atoms and hydrogen, to react a fluorine ion in the fluorine-containing aqueous solution with the disiloxane compound, obtaining a first reaction liquid containing a monofluorosilane compound represented by general formulas RaRbRcSiF and RdReRfSiF.
US10562797B2 Liquid treatment apparatus including flow channel, first and second electrodes, insulator surrounding lateral surface of first electrode, gas supply device, and power supply source
A liquid treatment apparatus includes a flow channel, first and second electrodes at least part of each of which is disposed within the flow channel, an insulator, a gas supply device, and a power supply source that applies a voltage between the first and second electrodes and generates plasma. The insulator has a tubular shape and an opening on an end surface of the insulator, and surrounds a lateral surface of the first electrode with a space interposed between the insulator and the first electrode. The gas supply device supplies and ejects a gas into the liquid via the opening. At least part of the flow channel extends in a first direction which is inclined with respect to a horizontal direction so that the liquid flows obliquely upward with respect to the horizontal direction. The opening is positioned within the at least part of the flow channel.
US10562794B2 Water purification system with active vibration
The water purification system for flow-coupled installation with a tap water inflow for producing a relatively purified water outflow includes a purification unit having a tap water inlet port for receiving tap water inflow and a purified water outlet port for dispensing purified water outflow from said purification unit. A particulate catalyst retained within the purification unit is in flow through relation relative to the water inflow and purified water outflow and catalyzes contaminants as the tap water inflow travels through the purification unit. An electrically induced particulate agitator associated translates vibration to the particulate catalyst for substantially preventing channeling therein during relatively slow tap water inflow through the purification unit.
US10562790B2 Wastewater evaporative separation systems
A wastewater evaporative separation system can include an evaporation panel assembly and a wastewater delivery system. The evaporative panel assembly can include at least 10 individual evaporation panels laterally joined together and fluidly coupled to a body of wastewater. The evaporation panel assembly can be configured for receiving wastewater from the body of wastewater and evaporating water therefrom as the wastewater cascades down the evaporation panel assembly and contaminants generally become more concentrated. The wastewater delivery system can be associated with the body of wastewater and can include a fluid directing assembly delivering wastewater from the body of wastewater to an upper portion of the evaporation panel assembly.
US10562783B2 Processing of alumina
Described herein are stable aqueous dispersions of alumina; methods of decreasing the viscosity of an alumina slurry; methods of decreasing the D50 of an alumina slurry; and methods of decreasing the level of hard packing in an alumina slurry, where the slurry comprises alumina feed material, water, and a dispersant agent.
US10562774B2 Method for separating carbon nanotube array from growth substrate
A method for separating a carbon nanotube array grown on a growth substrate from the growth substrate includes providing a carbon nanotube array grown on the growth substrate. The carbon nanotube array includes a plurality of carbon nanotube, each of the plurality of carbon nanotubes includes a top end and a bottom end, and the bottom end is bonded to the growth substrate. The bottom end is oxidized to form an oxidized carbon nanotube array. And then the oxidized carbon nanotube array or the growth substrate is applied to a force.
US10562766B2 Nanoscale apertures having islands of functionality
Methods, compositions and arrays for non-random loading of single analyte molecules into array structures are provided. Arrays of confined regions are produced wherein each confined region comprises a single island within the confined region. The island can be selectively functionalized with a coupling agent to couple a single molecule of interest within the confined region.
US10562763B2 Fence structure to prevent stiction in a MEMS motion sensor
The present disclosure relates to a microelectromechanical systems (MEMS) package featuring a flat plate having a raised edge around its perimeter serving as an anti-stiction device, and an associated method of formation. A CMOS IC is provided having a dielectric structure surrounding a plurality of conductive interconnect layers disposed over a CMOS substrate. A MEMS IC is bonded to the dielectric structure such that it forms a cavity with a lowered central portion the dielectric structure, and the MEMS IC includes a movable mass that is arranged within the cavity. The CMOS IC includes an anti-stiction plate disposed under the movable mass. The anti-stiction plate is made of a conductive material and has a raised edge surrounding at least a part of a perimeter of a substantially planar upper surface.
US10562760B2 Support pillar
The present invention disclosed a micro acoustic collector with a lateral cavity, comprising: a base metal layer; a movable film, an annular side wall; a lateral metal layer. The movable film faces towards the base metal layer to form a hollow space. The lateral metal layer is formed at a side of the movable film and around the movable film, fixed by the annular side wall and spaced apart from peripheral of the movable film by a distance, and the lateral metal layer faces towards the base metal layer to form a lateral cavity to assist an acoustic collection.
US10562759B2 Support pillar
The present invention disclosed a micro acoustic collector and CMOS microphone single chip. The micro acoustic collector comprising: a plurality of leaf-shaped structures annularly arranged with symmetry, each of the plurality of leaf-shaped structure having a suspended arm and a restrained arm, and the suspended arm of the plurality of leaf-shaped structures connected to a suspended fulcrum, and a plurality of through-vias formed in the suspended fulcrum and the plurality of leaf-shaped structures; a plurality of support pillars uniformly disposed under edges of the plurality of leaf-shaped structures corresponding to the restrained arms and the suspend arms; and a base metal layer formed under and insulated from the plurality of support pillars, and facing towards the inner-annular-supported acoustic collection film to form a hollow space.
US10562757B2 Product dispensing system
A system for controlling selection and distribution of a product in a product dispensing system. The system includes a user interface for prompting a selection and selecting the product, a machine control processor in communication with the user interface, a power distribution module connected to the machine control processor, and a power supply unit for supplying power to the system through the power distribution module.
US10562756B2 Vent flow guide for fill head
An exemplary system for improving gaseous venting from a fluid storage vessel includes a hollow member configured to receive a fuel nozzle, the fuel nozzle having an aspirate opening, a vent line fluidly connecting the fluid storage vessel and the hollow member, and a flow guide device fluidly connected to the hollow member and the vent line. The flow guide device includes a flow guide chamber having an inlet, a plurality of sidewalls, and an outlet, and a plurality of directional blades formed within the flow guide chamber. The plurality of directional blades direct a fluid flow through the flow guide chamber and the hollow member toward the aspirate opening of the fuel nozzle.
US10562752B2 Systems and methods for beverage preservation
A receptacle for storing, pressurizing, and dispensing packaged beverages. The receptacle includes an airtight chamber with a removable lid, wherein the joint between the lid and the chamber is also airtight. A gas valve allows for the inflow and outflow of gas, and a tap port and tap stem allow the beverage to be dispensed without breaking the seal of the chamber. A pressure relief valve allows for more rapid depressurization. The chamber can be used at high and low pressures, such as a partial vacuum, to prevent oxidation of a number of open beverages, such as beers, wines, and sodas. A pressure gauge port coupled with an optional pressure gauge allows a user to verify the appropriate pressure for the type of beverage being preserved. The gas valve may be disposed on a base of the receptacle, as may the pressure relief and/or the pressure gauge port.
US10562750B2 Beverage dispensing device for dispensing different types of beverages or beverage components
A beverage dispensing device dispenses different types of beverages or beverage components. At least one type of beverage is a malt based beverage or beverage component. The dispensing device has multiple supply lines each extending from a corresponding supply source and having a controllable supply line valve as well as a controlling device for sequentially setting the controllable supply line valves. A beverage dispensing device contains multiple beverages or beverage components to be dispensed into a receptacle after every sequence step has been executed and during a single tapping cycle.
US10562746B2 Mast support device
Embodiments herein relate to impact dampening blocks that may be located in footprints of channels of a mast. The impact dampening blocks may facilitate relief of at least some tension from a lift chain when a moveable member is lowered onto the impact dampening blocks. Other embodiments may be described and/or claimed.
US10562742B2 Self-maintaining crane system within a hostile environment
A self-maintaining crane system including a bridge, a trolley, a hoist, and sensors for use within a hostile environment, such as a wastewater treatment facility, is presented. The bridge is movable away from the bridge home position and back toward the bridge end position. The trolley is movable away from the trolley home position and back toward the trolley end position. The cable is extendable away from the hoist home position and retractable toward the hoist end position. The sensors separately determine whether the bridge, trolley, and cable engage a home position and end position. Sensors facilitate automated movement of bridge, trolley, and cable so as to minimize functional impairment of the crane system by the hostile environment.
US10562741B2 Method for modernizing an escalator or a moving walkway
The application relates to a method for modernizing an existing escalator or an existing moving walkway. The method can include removing all the electrical and mechanical parts from the existing framework of the existing escalator or of the existing moving walkway, the existing framework having two framework side parts and a base structure connecting said framework side parts, and the framework side parts being connected to each other by means of cross members disposed at a distance from the base structure; and replacing the existing cross members of the existing framework with new cross members, the two framework side parts of the existing framework being connected to each other in a mutually stabilising manner at least one point at a distance from the base structure of the framework, during replacement of the cross members.
US10562739B2 Synchronized electronic safety actuator
A selectively operable braking device for an elevator system. The braking device includes a safety brake adapted to be wedged against a guide rail when moved from a non-braking state into a braking state. Also included is an engagement mechanism moveable between an engaged position and a non-engaged position, the engagement mechanism comprising bar pinions each having teeth and connected to at least one of the other bar pinions with a meshed engagement of the teeth, the engagement mechanism configured to move the safety brake between the non-braking state and braking state when the engagement mechanism moves between the non-engaged position and the engaged position. Further included is a plurality of magnetic brake pads, each of the brake pads coupled to one of the bar pinions, wherein movement of one of the brake pads into the engaged position causes movement of the other magnetic brake pads into the engaged position.
US10562735B2 Stop ball
A stop ball for a tube for fluid or energy is provided. The stop ball comprises a singular hollow body. The hollow body comprises and is integral with a first opening for the tube and an attachment means for attaching the stop ball to the tube, the attachment means comprising a second opening for the tube. A method for attaching a stop ball according to any one of the preceding embodiments to a tube for fluid or energy is provided. The method comprising inserting the tube through all three openings; pulling the attachment means at least partly out of the hollow body; and clamping the attachment means onto the tube.
US10562733B2 Sheet processing device including a staple binding unit and a stapleless binding unit and image forming system
A sheet processing device is for binding sheets together. The sheet processing device includes binding units differing from each other in maximum sheet count, the maximum sheet count being a maximum number of sheets that can be bound at a time; a sheet tray configured to hold sheets until all to-be-bound sheets are placed therein, the number of the to-be-bound sheets being a largest one of the maximum sheet counts of the binding units or smaller; and a stacked-sheet-count limiting unit situated in a thickness direction of the sheets held in the sheet tray. The stacked-sheet-count limiting unit is configured to limit the number of sheets held in the sheet tray by varying a distance from a sheet support surface of the sheet tray on which the sheets are placed, depending on one of the binding units by which the sheets held in the sheet tray are to be bound.
US10562730B2 Image recording apparatus
An image recording apparatus includes: a recording unit configured to record an image on a sheet conveyed in a conveyance direction; conveyance rollers arranged downstream of the recording unit in the conveyance direction to be apart from each other in a width direction orthogonal to the conveyance direction; first spur rollers arranged opposingly to the conveyance rollers respectively and configured to nip the sheet between the conveyance rollers and the first spur rollers; second spur rollers arranged between the mutually adjoining first spur rollers respectively in the width direction; and a first guide member arranged upstream of the first spur rollers and the second spur rollers in the conveyance direction; and having a first guide surface configured to guide the sheet to a nip position at which the sheet is nipped by the conveyance rollers and the first spur rollers.
US10562727B2 Glass roll and method of processing glass roll
A roll-to-roll apparatus reliably reduces breakage of a glass film even in a case of sequentially performing predetermined processing on the glass film. Provided is a glass roll (1) formed by winding a glass film (2) into a roll, in which a resin film (4) is attached onto the glass film (2), and at least a part of the resin film (4) is arranged on a front side of an unwinding direction relative to a leading end portion in the unwinding direction of the glass film (2).
US10562725B2 Device for rewinding and forming a paper roll and related method
A device for rewinding and forming a paper roll in a rewinding machine comprising three rollers with parallel axes and perpendicular to the paper feeding direction, wherein two lower and upper winding rollers supported on a frame cooperate with a third swivel roller in pressure on a roll being formed, the paper being wound provided with a series of transverse piercing and weakening lines spaced apart according to regular intervals along their longitudinal development passing on the upper winding roller and finished roll exiting from an output opening defined between the lower roller and the third roller, the cores for the rolls fed one after the other by a conveyor, wherein mechanical tearing means are placed in the upper roller along its development facing towards the side of the paper facing towards the upper roller to positively act directly at a piercing line and cause the tearing of the paper.
US10562724B2 Image forming apparatus and feeding apparatus
A feeding apparatus includes a feeding member, first and second conveying members, a separation member, and drive and control units. The feeding member feeds a recording material placed on a tray. The separation member and the first conveying member form a nip portion and separates recording materials at the nip portion. The second conveying member conveys a conveyed recording material. The drive unit drives at least the feeding member. The control unit controls to feed first and second recording materials such that a second recording material front edge passes the nip portion before a first recording material rear edge passes the nip portion, and controls to stop the second recording material after the second recording material front edge has passed the nip portion such that the first recording material rear edge reaches the second conveying member before the second recording material front edge reaches the second conveying member.
US10562721B2 Feeder and backlight production apparatus
The present disclosure provides a feeder and a backlight production apparatus. The feeder includes: a storing assembly configured to store a material tray on which a plurality of elements to be fed are placed; a fetching assembly configured to obtain the material tray from the storing assembly by sucking and transport the material tray; a distributing assembly configured to obtain at least one element to be fed by sucking from the material tray transported by the fetching assembly, and distribute the at least one element to be fed; and a turn-over assembly configured to turn over the at least one element to be fed distributed by the distributing assembly, and transport the at least one element to be fed to a next process unit.
US10562718B1 Variable spacing device
A variable spacing device includes a support member, a driving member, a number of movable graspers, a limiting block, and a pushing block. The movable graspers are slidably mounted in a line on the support member. Each movable grasper grasps a workpiece. The limiting block is mounted on the support member and arranged in parallel with the pushing member. The limiting block defines first sliding grooves having a length gradually decreasing along a same direction. The pushing block defines second sliding grooves having a length gradually increasing along a same direction. Each movable grasper moves within a corresponding one of the first sliding grooves and a corresponding one of the second sliding grooves. Two sidewalls of each first sliding groove and two sidewalls of each second sliding groove resist movement of the corresponding movable grasper.
US10562715B2 Method and apparatus to diagnose a linear synchronous motor system
A method and system for detecting and reporting component failures in a linear drive system may identify failed position sensors, failed position magnets, and failed drive coils in the linear drive system. As a mover travels along a track segment in the linear drive system, signals corresponding to the position of the mover and to the current commanded in each drive coil are stored. Analysis of the stored signals identifies whether one of the position sensors along the track segment, one of the position magnets on the movers, or one of the drive coils, used to propel the movers along the track, has failed.
US10562712B2 Tray supplier and tray supply method
A tray supplier which performs supplying and collecting of trays includes a supply-side tray storage unit, a collection-side tray storage unit, a first tray placer and a second tray placer on which the trays are placed, and a first placer mover and a second placer mover which respectively move the tray placers between the supply-side tray storage unit and the collection-side tray storage unit, in which a first movement shaft of the first placer mover and a second movement shaft of the second placer mover are disposed parallel to each other, lifting and lowering units which lift or lower the first tray placer and the second tray placer are provided, and interference between the placer movers does not occur.
US10562710B2 Method for controlling variable production line using skid-type variable workbench and apparatus using the same
A method for controlling a variable production line using a skid-type variable workbench and an apparatus for the same. According to the method, a process group including multiple variable workbenches may be organized based on a design, each of the multiple variable workbenches may be mounted on an upper part of a skid board, the skid board may be loaded on a powered line that moves at a regular speed in a fixed direction, the skid board may be moved in consideration of a position of a worker responsible for each process and a work state of the process group, and movement of a target variable workbench may be stopped by removing a skid board, on which the target variable workbench corresponding to an unload instruction in the process group is mounted, from the powered line when the unload instruction is input by a worker.
US10562708B2 Roller system having spaced apart external rotor motor
A roller system has a frame, a plurality of rollers (supported by the frame) forming a roller plane, and an external rotor motor (“motor”) spaced from the roller plane. As an external rotor motor, the motor has a stator and an external rotor radially outward of the stator to substantially circumscribe the stator. To kinetically couple the motor with the rollers, the system also has a transmission coupling coupled with the external rotor and at least one of the rollers. The transmission coupling and external rotor are configured so that rotation of the external rotor causes the at least one roller to rotate in response to a torque received through the transmission coupling.
US10562705B2 Storage and retrieval system
A storage array in an automated storage and retrieval system includes storage spaces arrayed on racks along picking aisles, multiple level decks, where at least one deck communicates with each aisle, where the decks and aisles are configured to define a rolling surface for an autonomous transport vehicle at each level of the decks, racks along at least one aisle at each level are at multiple rack levels that are accessed from a respective rolling surface that is common to the multiple rack levels, and a vertical pitch between rack levels varies for a portion of a respective aisle, the vertical pitch between at least two rack levels of the portion of the respective aisle is related to another vertical pitch between at least two other rack levels of another aisle portion of the respective aisle so the vehicle effects multiple picks in ordered sequence in a common aisle pass.
US10562703B2 Refuse collection apparatus
A refuse collection apparatus is disclosed. A refuse collection apparatus according to one embodiment of the present invention a main body unit into which a refuse is inserted, a refuse compression unit installed in the main body unit and configured to compress the refuse inserted into the main body unit and a movement range detection unit located inside of the main body unit and configured to detect a movement range of the refuse compression unit.
US10562701B2 Web of cleaning products having a modified internal atmosphere and method of manufacture
A web (8) of cleaning products (10) and a method of manufacturing the same is disclosed. The web includes first (20) and second carrier (30) sheets and a plurality of pouches (50) containing a cleaning composition. Each of the pouches is disposed in a respective depression (26) formed in an upper surface (28) of the first carrier sheet. A first internal atmosphere (80) is enclosed within each of the pouches. The first carrier sheet is sealed to the second carrier sheet such that a second internal atmosphere (82) exists between the second carrier sheet and the plurality of pouches. The second internal atmosphere has a greater absolute pressure (P) than the first internal atmosphere so that the plurality of pouches and at least a portion of the cleaning composition in the plurality of pouches are compressed into the plurality of depressions in the first carrier sheet by the second internal atmosphere.
US10562698B2 Package for disposable coated acupuncture needle
A package holding acupuncture needles comprises a packaging tray having a needle supporting board with positioning groves defined thereon for securely supporting and positioning acupuncture needles therein; a moveable headrest pivotably attached to an end of the packaging tray; a plurality of acupuncture needles each including an elongate needle body securely received in the corresponding groove, and having a shank extending into the moveable headrest, each of the acupuncture needles including a collapsible film jacket enveloped on the elongate needle body; a sealing bag enveloping the packaging tray and the moveable headrest with the acupuncture needles thereon; and when the sealing bag is removed from the packaging tray, the moveable headrest can be rotated between a horizontal position and a substantial vertical position to support the packaging tray in a way that the shanks of the acupuncture are exposed for being readily retrieved from the packaging tray.
US10562697B2 Compact aerosol container
An aerosol container includes a single piece or a two-piece mounting cup that is concave and, preferably, enables stacking and is lightweight.
US10562696B2 Container for storing and individually discharging capsules
A container for storing capsules and discharging them individually, including an upwardly open capsule-holding receptacle, a cap rotatably mounted on the receptacle, an upright screw shaft with an external spiral groove fixedly mounted in the receptacle, and a hollow cylinder concentrically surrounding the screw shaft within the receptacle and coupled to the cap for rotation therewith. A thread on the inner surface of the cylinder faces and cooperates with the spiral groove to receive capsules admitted from the receptacle through an entry port in the cylinder and, as the cap is rotated, to raise the admitted capsules one by one to a central discharge port in the cap.
US10562694B2 Thermally insulated containers
A thermal conditioning wall panel (10) for use in a thermally insulating container comprises a panel body (22) having a channel (26) formed therein along one face thereof for receiving one or more thermal conditioning elements (12). At least one foot (32) is formed at the lower end of the body (22) for engagement within a socket provided on the thermally insulating container. The panel further comprises thermal conditioning element retaining elements (40) provided adjacent the longitudinal edges (29) of the channel (26), the retaining elements (40) projecting over a peripheral portion of the channel (26) for retaining the thermal conditioning elements (12) within the channel (26).
US10562693B1 Multiple condiment container assembly
A multiple condiment container assembly includes a container and dividers positioned to define chambers within the container. Each of the chambers can contain a respective condiment. A lid is removably coupled to the container and has a plurality of openings. Each opening is aligned with a respective chamber when the lid is coupled to the container. Each of a plurality of first panels is hingedly coupled to the lid and aligned with a respective one of the openings in the lid and each of the first panels has an aperture extending therethrough. The aperture in each of the first panels is in fluid communication with the respective opening in the lid to dispense the condiment contained in the chamber into which the respective opening extends. A plurality of second panels is each hingedly coupled to a respective one of the first panels closing the aperture in the respective first panel.
US10562689B2 Woven plastic bags with features that reduce leakage, breakage and infestations
A woven laminated plastic bag having features that further prevent leakage of contents out of the bag, or infestation of organisms into the contents of the bag is provided. In various aspects the bag can be fabricated from woven polypropylene and/or polyethylene layer which can be laminated with a film layer, can form a pinch bottom bag, and can have one or both sides include graphics and/or printing. The bag can also provide a top end and/or a bottom end either or both of which provide a discrete area which may contain discrete graphics and/or printing. The bag can also include a tape covered easy open feature that facilitates removal of tightly adhered sealing tape.
US10562682B2 Closure assembly for a container
The invention relates to a closure assembly (1) for a container (2) and a container thereof. The invention more particularly relates to a closure assembly which provides leak tight closure for liquid or viscous products and can be simply opened or closed by minimal effort and additionally can be inverted to stably rest on a horizontal surface to act as a tottle.
US10562681B2 Dispensing closure for a fluid container
The present invention relates to a dispensing closure comprising a base element, which can be attached to a neck of a container, a flip-top lid, being attached to said base element by a hinge and being movable between a closed and an opened position, and a tamper-evident element extending in a circumferential direction around at least part of the circumference of said dispensing closure, wherein the tamper-evident element has at least one weakening region extending at least over part of the height of the tamper-evident element and/or wherein a shoulder region of the base element, to which frangible elements of the tamper-evident element are attached, is inclined such that it declines in an outward direction of the base element.
US10562680B2 Formed thermoplastic article having a smoothly-curved distal periphery
The disclosure relates to forming shaped thermoplastic articles having smooth peripheries. Many thermoplastic articles have sharp edges formed upon molding or cutting the article from a feedstock sheet. Such sharp edges can damage thin plastic films or flesh which they contact, and smoothing the edges is desirable. Described herein are methods of forming a smooth periphery for such sharp-edged articles by rolling over the sharp edge. The smoothing operation is performed by forming a deflectable flange including a bend region separated from the potentially sharp peripheral edge by a spacer, deflecting a portion of the deflectable flange, and softening at least one bent portion of the deflectable flange to yield a smooth periphery upon cooling. A liner sheet may be attached to the feedstock sheet prior to, during, or after forming and can be peelable therefrom.
US10562679B2 Tamper-evident closing element and receiving structure
A combination of a closing element (28) and a receiving structure (24) is provided wherein the closing element (28) and receiving structure (24) are in an initially assembled orientation which prevents, but which can be subsequently operated to permit, communication through the receiving structure (24). The receiving structure (24) includes at least one laterally projecting shear member (40) and a spout (30) defining (A) an access passage (32). The closing element (28) has an aperture (78) for receiving a shear member (40) of the receiving structure (24). At least one frangible bridge (78) extends across a portion of the aperture (74) for being severed by the shear member (40) during relative rotation between the closing element (28) and the receiving structure (24).
US10562674B2 Plastic formed body for pouring out liquid
A plastic formed body having a pouring port 110 for pouring out highly wetting liquid that wets plastics to a high degree, wherein at least either a surface 110b that becomes a liquid-drip flow passage when said liquid drips at the pouring port 110 or a surface 110a that becomes a flow passage when said liquid is poured out, is coated with a fluorine-contained resin, and a surface of the fluorine-contained resin coating has an arithmetic mean roughness (Ra) in a range of 0.4 to 200 μm in the surface roughness measurement and an element mean height (Rh) in a range of 0.04 to 10 as defined by mean height (Rc)/element mean length (RSm) in the linear roughness measurement. The formed body effectively prevents said highly wetting liquid from dripping at the pouring port 110.
US10562671B2 Packing container for display panel
A packing container for accommodating a display panel is described. The packing container includes a packing main body having a receiving recess, which includes a first receiving zone and a second receiving zone, and a limiting element disposed on the second receiving zone, wherein the limiting element and the sidewall of the second receiving zone form a limiting accommodating space to constrain and accommodate a circuit board of the display panel.
US10562664B2 Resealable beverage can lid
A resealable beverage can lid has a top side having a first scored opening and a bottom side, a first rivet formed in the lid and extending outwardly from the top side of the lid, the first rivet having an indentation formed in the bottom side of the lid, the first rivet having a scored first circumference, a tab portion connected to the first rivet, a second rivet connected to the indentation of the first rivet, and a closure element connected to the second rivet.
US10562655B2 Device for altering the jet shape of pourable products
A device is illustrated and described for altering the jet shape of pourable products, in particular of foodstuffs, including an entry region for the entry of the pourable products, an exit region for the exit of the pourable products, and several ducts for conveying the pourable products, wherein each duct has at least one inlet associated with the entry region and at least one outlet associated with the exit region. The use of this device for the filling of foodstuffs and a method for the production of this device are also illustrated and described. In order to achieve that the shape and the velocity profile of the filling jet can be adjusted simply and gently, it is proposed that at least one of the ducts is curved, at least in sections.
US10562651B1 Apparatus for inserting an insert into the throat of a liquid container
An apparatus is provided for inserting container inserts into the throats of liquid containers. The apparatus includes an elongated and inclined container insert support tray having an outer end and an inner end with the insert support tray being mounted on a support frame. The insert support tray is vibrated to cause the container inserts therein to move towards the inner end thereof. An insert positioner is mounted at the inner end of the container insert tray. The apparatus also includes a vertically disposed inserter which is mounted on a sub-frame which is horizontally movably mounted on the support frame. The inserter is vertically movable to insert a container insert positioned therebelow into the throat of the container.
US10562650B2 Corrugated payload adaptor structure
A spacecraft. The spacecraft includes a rocket engine; a first stage connected to the rocket engine; and a payload stage connected to the first stage. The spacecraft also includes a payload structure inside the payload stage between a first compartment of the payload stage and a second compartment of the payload stage. The payload structure may be a single shell that has a corrugated shape such that an inside surface and an outside surface of the payload structure vary in shape to form the corrugations.
US10562646B2 Single-point release mechanism for spacecraft
A spacecraft includes a main body, a set of panels attached to a side of the main body, and a retaining the set of panels adjacent to the main body. The single-point release device includes a heater for generating heat to expand a thermally sensitive material, a membrane-based actuator for providing a linear movement based on a phase change of the thermally sensitive material contained in the membrane-based actuator, and a release fitting and a release rod for retaining and selectively releasing a pin based on the linear movement of the membrane-based actuator. The membrane-based actuator is configured to push the pin through the release fitting.
US10562643B1 Contingency landing site map generation system
A computer system determines contingency landing sites for an aircraft, piloted or autonomous. The computer system decomposes data from various types of maps into multiple separate risk maps, which can include: one for the risk to people being present on the ground at the landing site; one for the risk of damage to property on the ground at the landing site; one for the risk of damage to the aircraft; and/or one for the risk to people on-board the aircraft. From these maps, the computer system generates a contingency landing site map that the aircraft can use to determine an appropriate landing site in the case of an emergency. The computer system can also perform landing simulations to determine the various risks.
US10562638B2 Cradle for a turbopropeller engine with integrated air inlet duct
The invention relates to a cradle (10) for an aircraft turbopropeller engine (12) of a substantially axial orientation, comprising a front arch (16) and a rear arch (18) extending transversely relative to said axial direction (A), said arches (16, 18) being open at their lower ends and connected to each other by at least one axial longeron (34) extending between said arches (16, 18), characterised in that the longeron (34) is arranged in an upper portion of the cradle (10) and is formed in a single piece with the front arch (16).
US10562637B2 Translucent illuminated evacuation slide
An inflatable evacuation slide is provided. The slide may comprise a slide surface with a tubular member coupled to the slide surface. The tubular member may comprise a translucent material defining a chamber internal to the tubular member. A light source may be directed into the chamber and configured to illuminate the tubular member from within the chamber.
US10562636B2 Environmental control system pack with an air supply manifold
An air supply manifold includes an outer duct, a first inner duct, and a second inner duct. The outer duct is configured to transfer a fluid from the outer duct inlet to the outer duct outlet and includes an outer duct inlet and an outer duct outlet. The first inner duct is disposed within and passes through the outer duct and includes a first inner duct inlet and a first inner duct outlet. The first inner duct inlet and outlet are disposed outside of the outer duct. The second inner duct includes a second inner duct outlet and inlet fluidly connected to the first inner duct. The second inner duct is disposed within the outer duct and branches off from the first inner duct. The second inner duct outlet is disposed outside of the outer duct.
US10562635B2 Personal device carrier and a passenger seat
A personal device carrier for a passenger seat. The personal device carrier has a backing plate integrated into a backside of the passenger seat and a folding tray assembly with a base adjustably coupled to the backing plate for vertical movement of the folding tray assembly relative to the backing plate. The folding tray assembly includes a tray rotationally mounted to the base and movable between a generally vertical stowed position and a generally horizontal deployed position for holding a personal device.
US10562629B2 Screen support configured for attachment to a backrest of a seat
A screen support configured to attach a screen to a seat equipped with a rear enclosure and including an attachment system configured to clamp the rods of a headrest of the seat, a support system including a limb connected to the attachment system and at least one support runner connected to the limb and configured to bear against the rear enclosure, and an engagement system configured to permit the temporary attachment of a screen and connected to the third limb.
US10562628B2 Restraint assembly for cargo system
A restraint assembly includes a fitting base, a bushing, and a restraint roller disk, according to various embodiments. The fitting base includes a fitting lower surface and a fitting upper surface that is angled relative to the fitting lower surface, according to various embodiments. The fitting base may be configured to be coupled, via an anchor, to a rail upper surface of a guide rail of the cargo system. In various embodiments, the bushing is configured to be disposed about the anchor. In various embodiments, the restraint roller disk includes a roller upper surface and a roller lower surface, wherein the restraint roller disk is configured to be rotatably coupled about the bushing and the roller lower surface is configured to engage the fitting upper surface of the fitting base.
US10562627B2 Tray mounted longitudinal guide with conveyance in the lowered position and vertical restraint in the raised position
A tray mounted lateral guide for use between trays of a cargo bay having a bay floor includes a main body defining a roller slot. The tray mounted lateral guide further includes a roller configured to be at least partially positioned in the roller slot and to facilitate conveyance of a pallet through the cargo bay. The tray mounted lateral guide further includes a lifter coupled to the main body and configured to be coupled to a tray and to maintain the main body in at least one of a lowered position or a raised position, the main body being further from the bay floor when in the raised position than when in the lowered position.
US10562626B2 Tandem wing aircraft with variable lift and enhanced safety
A tandem wing aircraft having a fore wing, an aft wing, and a middle wing, attached relative to the aircraft and each other such that the middle wing provides a substantial portion of the total lift at landing speeds, and a minimal portion of the total lift at cruise speeds. At cruise speeds, induced drag is minimized, permitting higher speeds, greater fuel efficiency, and/or greater payload. Advantageously, the wing loading at cruise speeds is higher providing better passenger comfort while still providing controllability and safety at landing speeds.
US10562621B2 Paramotor fully articulated/adjustable swing arm system and hoop tensioner system
A fully articulable and adjustable swing arm assembly for a paramotor. The assembly includes a swing arm, a spherical bearing, an arm peg, and a pair of limiting disks. The arm peg extends through a central opening of the spherical bearing, and the pair of limiting disks are located proximate to the spherical bearing. The inner faces of the pair of limiting disks include a taper such that a clearance is formed between each of the opposing faces of the swing arm and a corresponding inner face of one of the limiting disks, permitting the swing arm to move in both a vertical and lateral direction. A lateral position of the swing arm assembly with respect to a frame of the paramotor is adjustable by sliding the arm peg into or out from an arm peg receiving block, which is then secured with a locking pin.
US10562617B2 Rotor hub vibration attenuator
A vibration attenuation system for attenuating vibrations in a mast of an aircraft includes a weight attached to the mast but free to orbit about the mast. The weight can be comprised of one or more weight assemblies. Embodiments can include a single weight, or plural weight assemblies wherein each weight assembly can include a mechanical interconnecting mechanism so that each weight assembly receives feedback regarding the position and movement of one or more other weight assemblies. Each weight can be associated with a spring that urges the weight towards a neutral position. Rotation of the mast can cause the weight to orbit about the mast and self-excite such that the weight acts against the urging of the spring towards an attenuating position.
US10562614B2 Aircraft landing gear, aircraft, and related methods
An aircraft landing gear structure includes a strut assembly configured to transition between a compressed configuration, an extended configuration, and a retracted configuration. The strut assembly has a compressed length, an extended length, and a retracted length, such that the compressed length and retracted length are less than the extended length. The strut assembly includes an upper tubular housing, an upper bulkhead configured to be translated between a lower position and an upper position, a lower tubular housing operatively coupled to the upper tubular housing, a lower bulkhead supported by the lower tubular housing, and a pressure chamber defined between the lower bulkhead and the upper bulkhead. A volume of strut liquid and a mass of strut gas are positioned within the pressure chamber. A method of retracting a strut assembly includes longitudinally translating an upper bulkhead within an upper tubular housing from a lower position to an upper position.
US10562613B2 Adjustable lift modification wingtip
An adjustable lift modification wingtip may be attached to a baseline wing of an aircraft. The adjustable lift modification wingtip may comprise a horizontal portion including a control surface and a vertical portion coupled to the horizontal portion. The vertical portion may move about an axis that may be substantially perpendicular to the horizontal portion. The control surface and the vertical portion may be adjusted in conjunction to increase wing efficiency at a flight condition.
US10562608B1 Variable pitch mechanisms for propeller blades using linear actuation
Various mechanisms for adjusting pitches of propeller blades are described. For example, the pitch adjustment mechanism may include a propeller hub enclosing a geared mechanism that cooperates with a compound gearbox having first and second planetary stages to adjust pitches of propeller blades. Alternatively, the pitch adjustment mechanism may include a propeller hub enclosing a pitch adjustment assembly that utilizes tension cables and torsion springs, or rack-and-pinion structures, to adjust pitches of propeller blades. Using any of the various mechanisms, the pitches of propeller blades may be rotated at least 90 degrees, and up to and exceeding 360 degrees, in order to effect thrust reversals and/or adjust thrust profiles.
US10562606B2 Wing, flap, and aircraft
The present invention is directed to reducing noise resulting from a wing tip vortex of a wing such as a flap. A flap of an aircraft includes a flap main body provided to a parent wing in a deployable manner, and a vortex generation portion including a protruding member, the protruding member being provided to protrude from an upper surface at least at an end of the flap main body on an outboard side in a span direction and forming a predetermined angle to an axial direction of the aircraft. A rear end of the protruding member is located on the side adjacent to a side-end edge at the end of the flap main body in the span direction relative to a virtual line passing through a front end of the protruding member and being parallel to the axial direction.
US10562602B1 System and method for maneuvering marine vessel with non-engine-powered propulsion device
A marine propulsion system includes an engine-powered propulsion device coupled in torque-transmitting relationship with an engine. A non-engine-powered propulsion device is coupled to a source of electric or hydraulic power. A control module is provided in signal communication with the engine-powered propulsion device and the non-engine-powered propulsion device. A user-operated input device is in signal communication with the control module. The marine propulsion system operates in a non-engine-powered propulsion mode in response to the control module determining the following: the engine was previously running; a speed of the engine is below an engine-stopped speed threshold; the marine propulsion system is on; and a request for movement of the vessel has been input via the user-operated input device. While the marine propulsion system operates in the non-engine-powered propulsion mode, the control module controls the non-engine-powered propulsion device to generate thrust to maneuver the vessel according to the request for movement.
US10562599B1 Rocket launch platform stabilization system
An offshore floating rocket launch platform (12) is disclosed. The platform (12) floats on the surface of a body of water (14). A rocket (16) and a rocket launch support tower (18) are shown on the top surface (19) of the platform (12) in preparation for launch. The platform (12) includes a statically buoyant chamber 20) and more than one variable buoyancy-generating variable buoyancy-generating chambers (22). A number of variable buoying-generating variable buoyancy-generating chambers (22) are capable of being pressurized with a fluid to provide counter-acting forces that compensate for position changes of the platform incurred by natural forces. Other embodiment of the invention may be used for floating offshore structures like buildings (26), bridges (46) and wind turbines (50).
US10562582B2 Optical sensor disposition structure for saddle riding vehicle
An optical sensor disposition structure of a saddle riding vehicle includes an optical sensor, left and right handle bar grips installed on both side portions of a handle bar pipe, and a switch case installed between the left and right handle bar grips and supported by the handle bar pipe, and the optical sensor is installed on the switch case.
US10562580B2 Shared infrared (IR) bicycle and methods
A preferred IR-bicycle comprises an infrared (IR) sensor and non-IR electronics. The IR sensor detects a person in the proximity of the IR-bicycle (i.e. a nearby person). Once the IR sensor detects a nearby person, the non-IR electronics switches from a first mode to a second mode, wherein the power consumption in the first mode is substantially lower than that in the second mode.
US10562576B2 Traction stud for endless tracks
A traction stud for endless tracks. The traction stud comprises a base and the base has a center point on a top surface and a center point on a bottom surface. There is an elongated shank rigidly surmounted on the top surface at the center point. The shank has a distal end. The distal end has at least one cutting flute located in it. The shank has a threaded surface. The base has, at the center point of the bottom, a means for torqueing the traction stud.
US10562574B2 Slider for track assembly of machine
A slider for a track assembly of a machine is provided. The slider includes an elongated base portion coupled to a frame and a sliding portion extending from the elongated base portion. The sliding portion includes an outer surface configured to slidably engage with a track link of the track assembly. The sliding portion includes a set of wear indicators defined in the outer surface. The set of wear indicators includes a first wear indicator and a second wear indicator. The first and the second wear indicators are located at a first predefined thickness and a second predefined thickness respectively, measured along a central axis of the sliding portion. Further, the first wear indicator indicates partial wear of the sliding portion and the second wear indicator indicates substantial wear of the sliding portion.
US10562571B2 Double-bend double-girder structure for scooters
The present invention discloses a double-bend double-girder structure for a scooter. A frame comprises a frame body; at a front end of the frame body, two girders arranged longitudinally in a front-rear direction, a mandrel arranged transversely in a left-right direction and fixed to the girders, and a tiller arranged vertically are provided; one shock absorber is fixed to each of left and right ends of the mandrel, and a lower end of the shock absorber is fixed to a front wheel bar, an outer end of which is fixed to a front wheel; and each of the girders consists of a front girder segment, a middle girder segment and a rear girder segment, the front girder segment being relatively located above the rear girder segment, and the middle girder segment being arranged between the front girder segment and the rear girder segment. The present invention has the advantages that the structural strength of the frame is increased, the concentration points of stress are reduced, the service life of the scooter is increased, the structure of the scooter frame is simplified, the stress distribution of the shock absorption system is optimized, and the comfort during the use of the scooter of the present invention is improved.
US10562565B2 Steering control method and system of self-driving vehicle
A steering control method and a steering control system for self-driving of a vehicle are disclosed. The method comprises obtaining information about an expected steering angle of a vehicle based on an automatic planning control operation; detecting whether an effective torque is applied to a steering wheel by a driver; and when it is detected that the driver has applied the effective torque to the steering wheel, computing a difference between a turning angle of the steering wheel controlled by the driver and the expected steering angle of a vehicle, and determining a self-driving intent prompt torque according to the difference between the two, wherein the self-driving intent prompt torque is to be applied to a steering system.
US10562562B2 Electric power steering apparatus
An electric power steering apparatus that easily obtains equivalent steering torques to vehicle information such as a steering angle without being affected by a road surface state and aging-changes of mechanism characteristics of a steering system. The apparatus includes a torsion bar provided in a column shaft of a steering wheel of a vehicle, and assist-controls a steering system by driving and controlling a motor connected to the column shaft based on a current command value. A target steering torque generating section generates a target steering torque based on vehicle driving information, a converting section converts the target steering torque into a target torsional angle, and a torsional angle control section calculates the current command value so that a torsional angle of the torsion bar follows the target torsional angle; and performs a control so that a detection torque of the torsion bar follows a value depending on driving information.
US10562559B2 Rack bar and method for manufacturing rack bar
Rack bar 10 for transmitting a steering operation to steered wheels while converting a rotational movement of a pinion shaft rotatably connected to a steering wheel into an axial movement, the rack bar being formed by conducting a die forging process on a material having an approximately circular cross section. A pair of face width-enlarged portions 15 is provided at both ends that rack teeth 14 have in face width direction. With this, it becomes possible to ensure face width dimension W of rack teeth 14 larger than outer shape S of a circular cross section of rack main body 13 (material), which results in an improvement of a contact gear ratio between the pinion teeth and the rack teeth.
US10562558B1 Foldable steering wheel system
A powered folding steering wheel system includes a rim having upper and lower rim sections that are pivotably connected to a primary structure to permit rotation of the upper and lower rim sections forwardly and rearwardly from a driving position. The system includes a powered drive assembly that is configured to rotate the upper and lower rim sections forwardly and rearwardly.
US10562557B2 Foldable golf trolley
A foldable golf trolley includes a standing tube assembly movably coupled with a front wheel assembly through a front wheel connecting rod. A bottom tube assembly is connected with the front wheel assembly and the standing tube assembly. A four-rod linkage is formed by the standing tube assembly, the front wheel connecting rod, the front wheel assembly and the bottom tube assembly. The standing tube assembly is connected with the left and right wheel assemblies through a left and right wheel connecting rod assembly respectively. The left/right wheel connecting rod assembly includes a left/right wheel driving connecting rod and a left/right wheel driven connecting rod, and a left/right wheel four-rod linkage is formed by the left/right wheel driving connecting rod, the left/right wheel assembly, the left/right wheel driven connecting rod and the bottom tube assembly. The trolley could be quickly folded into a compact structure and unfolded.
US10562556B1 Folding wagon having fold-down seats
Disclosed herein is a folding wagon that is capable of being folded between an expanded open configuration at which a variety of articles or children are carried in a basket of the wagon and a compact collapsed configuration to facilitate storage or transport when the wagon is not being used. A pair of fold-down seats which are carried inside the basket to transport small children are rotatable between a vertically upright position and a horizontally flat position. A handle is pivotally coupled to the front of the wagon and rotatable between a first position lying inside the basket and a second position extending outwardly from the front of the wagon. A handlebar is pivotally coupled to the rear of the wagon and rotatable between a first position extending horizontally outward from the rear of the wagon and a second position extending vertically downward alongside the wagon.
US10562553B2 Railyard crew member vest for use within a railyard
The present invention relates to a smart vest for use by railyard personnel at a railyard. The smart vest utilizes many safety features, such as improved visibility, a real-time camera, an environmental monitor, high-accuracy location tracking, tracking the “state” of the railyard crew member, real-time communication, and mobile power. Each of these features may be incorporated with the smart vest.
US10562552B2 System for railway monitoring
A system for monitoring a grade crossing is provided. The system may include a sensor co-located with a signage apparatus. The sensor may include a sensing area covering a portion of the grade crossing and a processor communicatively coupled to the sensor. The processor may be configured to receive data originating from the sensor and transmit said data to an analytics module communicatively coupled to the system.
US10562550B2 Slack adjuster for a brake system with increased take-up capacity
A slack adjuster for use with a railway braking system which has an increased let-out length that enables the use of brake shoes having an increased thickness. The slack adjuster includes at least one of a dual spring and canister assembly, an external yoke trigger, or a combination of both a dual spring and canister assembly and an external yoke trigger. A method of retrofitting a truck mounted brake system is provided, in which the slack adjuster is positioned within the brake system in order to increase the let-out length while maintaining a predetermined spatial envelope within the brake system. The slack adjuster has an increased let-out length enabling the use of thicker brake shoes without requiring modification of the interacting components of the truck mounted brake system since the overall size of the slack adjuster remains the same.
US10562548B2 Attachment of articulated connectors in multi-unit freight cars
Articulated connectors are attached to and extend from center sills of adjacent car units of a multi-unit railroad freight car, connecting the car units to each other and to a shared truck. The center sill of each of the car units includes a top member that is of increased thickness at the outer end of the center sill. A weld extending along a shoulder that extends around the main body of s portion of the articulated connector attaches the articulated connector portion to the outer end of the center sill with ample strength to carry draft and buff train loads as well as the weight of the car unit and its lading, without the need for weld joints inside the center sill.
US10562547B2 Railcar truck roller bearing adapter pad systems
A railcar truck and adapter pad system for placement between a roller bearing and side frame pedestal roof of a three-piece railcar truck. Many different features of the pad and/or the adapter-pad interface are configured to improve stiffness characteristics to satisfy both curving and high speed performance of the railcar truck.
US10562546B2 Mechanism for operating a railcar discharge gate assembly
A mechanism for operating a discharge gate assembly mounted on a railcar. The gate assembly includes a frame defining a discharge opening, a door slidably positioned on the frame for a generally horizontal range of movements between a closed position and an open position. An operating shaft assembly is mounted on the frame for rotation about a fixed axis and is operably coupled to the door such that the door moves in response to rotation of the operating shaft assembly. The mechanism for operating the discharge gate assembly includes a mount carried by and with the railcar and an actuator carried by the mount outside a range of travel of the slidable door. A force transfer mechanism is operated by the actuator for rotating the operating shaft assembly to slidably move the door between the closed and open positions in response to operation of the actuator.
US10562545B2 Covered hopper car with stiffened bulkheads
A covered hopper car including a plurality of hoppers adjacent one another along the length of the car, with a generally vertical stiffened bulkhead of sheet material between adjacent ones of the hoppers. The bulkhead may include a plurality of stiffeners of which each stiffener is a transversely oriented curved portion of the sheet material of the bulkhead itself, displaced from the vertical main plane of the bulkhead. A radius of curvature is great enough and all surfaces of the stiffener are steep enough that granular material will slide downward from the stiffener and all surfaces of the stiffener can easily be washed by a spray directed from a hatch opening in the roof of the covered hopper car.
US10562541B1 Contextual autonomous vehicle support through speech interaction
An autonomous vehicle including a sensor system that outputs a sensor signal indicative of a condition of the autonomous vehicle. The vehicle also includes a communication system including a speaker. Based upon a profile of the passenger, the autonomous vehicle can determine that support is to be provided audibly to the passenger when the support is provided to the passenger. Moreover, the autonomous vehicle can detect occurrence of an event that has been identified as potentially causing discomfort to the passenger based upon the sensor signal output by the sensor system. Responsive to detecting the occurrence of the event, and in accordance with the profile of the passenger, the autonomous vehicle can cause the speaker to output an audible support message. Content of the audible support message is based on the detected event, and the audible support message solicits feedback from the passenger of the autonomous vehicle.
US10562534B2 Vehicle drive assistance system and vehicle drive assistance method
A vehicle drive assistance system is provided, which includes a processor configured to execute a required driving ability estimating module to estimate a driver's required driving ability required for driving a vehicle based on a traffic environment around the vehicle and drive assistance provided to the driver by the vehicle, a current driving ability estimating module to estimate a driver's current driving ability, and a changing module to perform increase processing in which the required driving ability is increased when the current driving ability is higher than the required driving ability.
US10562533B2 Bicycle controller and bicycle control system including bicycle controller
A bicycle controller includes an electronic control unit that controls a transmission unit and a motor in accordance with a shift request that changes the transmission ratio. If the transmission ratio is changed in multiple steps in accordance with the shift request, then the electronic control unit selectively executes one of first and second shifting operations. In the first shifting operation, the output of the motor is limited and the transmission unit is operated to reach a requested transmission ratio that corresponds to the shift request. In the second shifting operation, the output of the motor is limited and the transmission unit is operated to reach an intermediate transmission ratio of the requested transmission ratio, and after the electronic control unit temporarily reduces the limitation on the output of the motor, the electronic control unit again limits the output of the motor and operates the transmission unit.
US10562529B2 Automatic transport system
The invention relates to an automatic transport system based on a network of one-way high-speed-traffic lanes (25, 26, 27, 28) without crossings or red lights, mainly on a pylon (13), dedicated to vehicles capable of operating in an automatic mode in which the driver plays no part in controlling the automotive vehicle. The transport system has stations for the travelers which are different from the entry and exit zones for the vehicles and has high-speed-traffic lanes and service lanes, so that not all of the vehicles are forced to go past the stations and the entry and exit zones.
US10562523B2 Vehicle control apparatus and vehicle control method
A vehicle control apparatus includes a thermal load priority calculator, a stability priority calculator, and a driving force distribution controller. The thermal load priority calculator is configured to calculate a thermal load priority that prioritizes a thermal load of a motor for driving a vehicle according to an operating state of the vehicle. The stability priority calculator is configured to calculate a stability priority that prioritizes a stability of the vehicle according to an operating state of the vehicle. The driving force distribution controller is configured to control a driving force distribution in a front and a rear of the vehicle, on a basis of a result of comparing the thermal load priority and the stability priority.
US10562522B2 Control apparatus for vehicular power transmitting system
A control apparatus for a power transmitting system of a vehicle includes a drive mode control portion for selectively establishing one of first and second engine-braking drive modes in which a braking torque of the engine is applied to the vehicle. The first engine-braking drive mode is established in an engaged state of the first coupling device, while the second engine-braking drive mode is established in an engaged state of the second coupling device. The drive mode control portion switches the power transmitting system between the first and second engine-braking drive modes, such that the engine speed is held constant in the process of switching between the first and second engine-braking drive modes.
US10562517B2 System and method of controlling driving of vehicle when battery charging is limited
A method of controlling driving of a vehicle when battery charging is limited is provided. The method includes calculating a target wheel torque from a speed of the vehicle, calculating a target motor torque from a differential gear device of the vehicle, and calculating a discharge power of a hybrid starter generator when the target motor torque and a motor charging limitation torque are compared with each other and the target motor torque is greater than the motor charging limitation torque. A fuel injection of the vehicle is blocked and an engine clutch is disengaged when the discharge power of the hybrid starter generator and a discharging limitation power of the hybrid starter generator are compared with each other and the discharge power of the hybrid starter generator is less than the discharging limitation power of the hybrid starter generator. Additionally, an engine reference speed of the vehicle is determined.
US10562514B2 Power transmission apparatus and vehicle, and power transmission control method
A power transmission apparatus has a power distribution mechanism which is connected to an engine and a first motor-generator an in which at least three rotation elements enable to rotate in differential motions to one another, a power combining mechanism which is connected to the power distribution mechanism, a second motor-generator and an output shaft and in which four rotation elements enable to rotate in differential motions to one another, a brake mechanism which enables to selectively fix a rotation element of the power combining mechanism and a brake mechanism which enables to selectively fix a rotation element of the power combining mechanism which is connected to the engine.
US10562512B2 Methods and systems for operating a driveline of a hybrid engine powertrain
Methods and systems are provided for adjusting clutch pressures and electric machine torques as a function of a stability metric threshold(s) in order to balance performance and charging of an onboard energy storage device. In one example, a method includes during an upshift of a transmission from a first gear to a second gear, adjusting a clutch pressure of the transmission to adjust slippage of a clutch in response to a vehicle stability control parameter exceeding a threshold. In this way, torque delivered to a transmission output shaft may be reduced, which may increase vehicle stability.
US10562510B2 Method and device for operating a brake system for a vehicle and brake system
A method for operating a vehicle brake system, including: classifying a fault signal, indicating a fault of an electronic actuating device of the brake system, the actuating device outputting a brake pressure for a brake of the vehicle in a normal operating mode and a pneumatic actuating device for outputting the brake pressure in a backup operating mode, as a fault signal of a first fault category if the fault is a fault in which a switchover from the electronic actuating device afflicted with the fault to the pneumatic actuating device leads to an improvement in the outputting of the brake pressure; and switching from the electronic actuating device to the pneumatic actuating device, to output the brake pressure using the pneumatic actuating device, if the fault signal is a fault signal of the first fault category. A related computer readable medium, apparatus and brake system are also described.
US10562508B2 Freight trailer brake clearing system
A brake clearing system useful for clearing mechanical components of one or more brake units provided on a freight trailer having an air storage reservoir. The system includes a flow controller, at least one delivery hose, and at least one discharge device. The flow controller is fluidly between the air storage reservoir and the auxiliary tank. The delivery hose is fluidly connected to an outlet of the flow controller and delivers pressurized air to the discharge device. The discharge device, in turn, is configured to direct pressurized air at components of one of the brake units. The flow controller can include an inflow control unit, an auxiliary tank, and an outflow control unit. In related embodiments, the auxiliary tank can include a heater.
US10562506B2 Brake pressure control unit
A brake pressure control unit for a motor vehicle brake system, having an electric motor, the rotational movement of which is transformed by a ball screw drive into a translational movement of a piston, in order for it to be possible to build up a defined brake pressure in a wheel brake independently of the actuation of a brake master cylinder. The electric motor is received in a first housing and the piston is received in a second housing which is arranged diametrically with respect to the first housing, and a third housing with two diametrical end surfaces is arranged between the first and the second housing, on which end surfaces the first and the second housing are fixed.
US10562503B2 Waveguide sensor with nanoporous surface layer
A waveguide sensor system is provided. The system includes a light source and a waveguide formed from a light transmitting material. Light from the light source enters the waveguide at an input area and travels within the waveguide by total internal reflection to an analyte area and light to be analyzed travels within the waveguide from the analyte area by total internal reflection to an output area. An optical sensor is coupled to the output area and is configured to interact with the light to be analyzed. The system includes a plurality of pores located along the outer surface within the analyte area and formed in the light transmitting material of the waveguide, and the pores are configured to enhance light interaction with the analyte within the analyte area.
US10562501B2 Vehicle light assembly and method of controlling same
A vehicle light assembly is provided. The vehicle lighting assembly includes a housing, a light source, a lens disposed in front of the light source, a light sensor disposed outside the lens for sensing light intensity of light output from the lens, and a controller controlling the light source to adjust intensity of the light based on the sensed light intensity. The controller may also control a lens cleaner based on the sensed light intensity.
US10562498B2 ATV windshield and wiper mounting
A windshield wiper mounting plate supports a wiper relative to a frame of an all-terrain vehicle. The windshield is hinged to the frame, and the windshield wiper mounting plate is separately hinged to the frame. The windshield can be pivoted relative to the frame, simultaneously pivoting the windshield wiper mounting plate and attached wiper. The windshield is received in a windshield mounting groove of the windshield wiper mounting plate. The windshield can be removed from the frame by sliding the windshield out of the windshield mounting groove and while leaving the windshield wiper mounting structure attached to the frame of the all-terrain vehicle.
US10562490B2 Occupant restraining device for vehicle
The occupant restraining device for a vehicle has a seatbelt, a collision predicting sensor, a braking device that enlarges a gap between a vehicle occupant and a seatback of a vehicle seat, an explosive-type pretensioner and electric motor that retract the seatbelt, and a control section that, in a case in which a front collision of the vehicle is sensed in advance by the collision predicting sensor, enlarges the gap between the vehicle occupant and the seatback by the braking device and starts retracting of the seatbelt by the explosive-type pretensioner and the electric motor, and at least until forward movement of the vehicle occupant starts after occurrence of the front collision, continues to input load to the vehicle occupant from the seatbelt and continues to move the vehicle occupant toward a vehicle rear side.
US10562488B2 Load limiting seatbelt retractor
A seatbelt retractor includes a base, a spool, a cylinder and a cylinder lock. The spool is rotatably coupled to the base and has a piston portion. The cylinder is engaged with the piston portion and therewith defines a first chamber. The piston portion is movable from a first position yielding a first chamber volume to a second position yielding a second chamber volume. The cylinder lock in a first condition rotatably fixes the cylinder to the base. Damping fluid is disposed in the chamber.
US10562480B2 Arm rest
An arm rest attachable to a seat for a vehicle occupant to sit on includes a pair of side members, a front member, and an airbag. The pair of side members are configured to be at left and right sides of the vehicle occupant when the vehicle occupant is seated. The side members extend in a front-rear direction and are coupled to the seat. The front member is configured to be in front of the vehicle occupant when the vehicle occupant is seated and is coupled to at least one of the pair of side members. The airbag is configured to deploy toward the vehicle occupant from the front member. When the vehicle occupant comes into contact with the deployed airbag, the airbag is supported by a reactive-force member from which a reactive force is obtained as a result of the airbag abutting on the reactive-force member.
US10562479B2 Operator protection apparatus with an over-center linkage
Aspects hereof relate to an operator protection apparatus having at least one over-center linkage. In some aspects, an operator protection apparatus can be raised and lowered by an operator from a seated position, for example, on a terrain working vehicle. Additionally, the at least one over-center linkage may automatically lock in the operator protection apparatus in a raised position. Accordingly, a mechanical force is then required to overcome the lock, and allow the operator protection apparatus to return to a lowered position.
US10562476B2 Guard assembly for a machine
A guard assembly for a machine is provided. The guard assembly includes a guard structure and a frame. The frame is attachable to the machine at a machine component. The guard structure is pivotably connected to the frame and movable between a first position and a second position. The frame further includes a magnet structure to releasably couple the frame to the machine component. Furthermore, the frame includes a cap being secured to the magnet structure. The cap includes a skin having at least one side extending beyond the magnet structure and contacting at least a portion of the machine component.
US10562474B2 Vehicle electrical system
The disclosure relates to a vehicle electrical system for a motor vehicle. The vehicle electrical system comprises: a low-voltage sub-system for at least one low-voltage load; a high-voltage sub-system for at least one high-voltage load; and a starter/generator; wherein the high-voltage sub-system is connected to the low-voltage sub-system by means of a coupling unit designed to draw energy from the high-voltage sub-system and to feed said energy to the low-voltage sub-system, wherein the high-voltage sub-system has a battery, which is designed to produce the high voltage and to output the high voltage to the high-voltage sub-system and which has at least two battery units having individual voltage taps, which are led to the coupling unit. The coupling unit is designed to selectively connect the battery units to the low-voltage sub-system. The disclosure further relates to a motor vehicle, comprising an internal combustion engine and such a vehicle electrical system.
US10562468B2 Wheel house with a wheel house cover
A wheel house cover (2) for a wheel house (1) of a motor vehicle (4) has a basic body (13) defining a segment of a circular ring with an outer side (14) and an inner side (15). The wheel house cover (2) is fastened to a body sheet (5) so that the outer side (14) is visible. The rear side (15) of the wheel house cover (2) has fastening crosspieces (16) each of which has a fastening opening (8, 17) and a fastening protrusion (18). The fastening opening (8, 17) receives a fastening element (10) to achieve interlocking connection of the wheel house cover (2) to the body sheet (5). The fastening protrusion (18) engages in a positioning opening (9, 19) of the body sheet (5) to position the wheel house cover (2) relative to the body sheet (5).
US10562462B1 Utility rack system
A storage system includes a utility rack having a base frame with a plurality of cross members extending across the base frame and an accessory. The accessory includes at least one attachment device for attaching to at least one of the cross members. The attachment device includes a cross member retainer configured to partially retain a cross member, a hinged brace configured to move between an open position rotated away from the cross member retainer and a closed position rotate towards the cross member retainer and configured to press against the cross member, and a latch configured to lock the hinged brace in the closed position and maintain a pressure of the hinged brace against the cross member.
US10562456B2 Front bumper slide-out step
An extendable and retractable step platform assembly is provided for a front of a vehicle to afford a user with a better view and reach for accessing an engine compartment. The step platform assembly includes a guide rail system coupled to a front frame of the vehicle. A step platform is coupled to the guide rail system. The step platform provides a substantially planar surface configured to support a load for an extended time. The step platform moves in a horizontal direction between a first position that is retracted behind a front bumper of the vehicle, and a second position that is extended beyond the front bumper of the vehicle.
US10562449B2 Accelerometer-based external sound monitoring during low speed maneuvers
Method and apparatus are disclosed for accelerometer-based external sound monitoring during low speed maneuvers. An example vehicle includes accelerometers affixed to windows of the vehicle, speakers located inside the vehicle, and an infotainment head unit. Each of the speakers is uniquely associated with one of the accelerometers. The infotainment head unit, when a speed of the vehicle satisfies a threshold, selects a zone corresponding to a direction of travel of the vehicle. Additionally, the infotainment head unit plays signals captured by the accelerometers associated with the selected zone on the corresponding speakers.
US10562445B2 Air-guiding arrangement
An air-guiding arrangement for an air vent, includes an air-guiding element and an operating element which is movable relative to the air-guiding element and has a manually actuatable operating portion arranged on a front side of the air-guiding element, a light source being arranged in the operating portion of the operating element, at least one electrical conductor being provided which is connected, on the one hand, to the light source and can be connected, on the other hand, to an electrical supply source, and, for electrical connection between the light source and the at least one electrical conductor, at least one elastic electrical connecting element being provided which, on the one hand, is held fixedly on the air-guiding element and, on the other hand, is held fixedly on the operating element, and which deforms elastically during a relative movement between the air-guiding element and operating element.
US10562444B1 License plate frame with emergency lighting
A license plate frame assembly a housing and a first plurality of lighting elements. The housing is adapted for mounting to a vehicle and has first and second generally opposed pairs of side members defining a central aperture dimensioned for a vehicle license plate to be visible therethrough. Each of the first pair of side members defines a first plurality of lighting element apertures therein. The first plurality of lighting elements is arranged in the housing under the first plurality of lighting element apertures, and mounted in the housing such that light emitted thereby from the first pair of side members is oriented along intersecting first axes at acute angles relative to a plane of the vehicle license plate.
US10562436B2 Portable dunnage bag inflator
Various embodiments of the present disclosure provide a portable dunnage bag inflator that provides a compact, pressurized source of air and that is easily mounted onto a movable cargo mover (such as a forklift truck or a pallet jack). Generally, the portable dunnage bag inflator includes an impellor-driven blower that, in operation, draws air at atmospheric pressure through an air intake grid or air inlet into the impellor and expels the air through an inflation hose. Since the portable dunnage bag inflator includes an impellor-driven blower, the pressure of the expelled air is higher than atmospheric pressure. This enables dunnage bags to be inflated to the desired specifications at point-of-use (e.g., during or after loading of cargo into a cargo container) and eliminates the need for a compressed air supply.
US10562431B2 Aftermarket stowable trailer ramp
A loading ramp assembly comprises a ramp body, a pivot bar, a first clamp and a second clamp. The ramp body includes a detent. The pivot bar includes a bore that receives the detent. The first clamp is disposed on the first side of the pivot bar and the second clamp is disposed on the second side of the pivot bar. The proximal end of the ramp body is rotatably connected to the pivot bar at a position on the pivot bar between the first clamp and the second clamp. The ramp body is rotatable on the pivot bar from a loading position to a stowed position and is also inwardly and outwardly slidable on the pivot bar. The first clamp and second clamp can assume a loosened configuration and a clamped configuration. In the loosened configuration the pivot bar is rotatably positionable such that the bore can assume a selected angular orientation. In the clamped configuration, the first clamp and second clamp apply a clamping force to the pivot bar that holds the pivot bar in a clamped position and maintains the bore in the selected angular orientation. One or more fasteners removably fasten the clamps to the floor. When the ramp body is rotated about the pivot bar and the detent is aligned with the bore, the detent engages the bore in the bore's selected angular orientation and holds the ramp body in the stowed position.
US10562430B1 Adjustable receptacle holder
An adjustable receptacle holder for securely supporting a receptacle within a vehicle comprises a telescopic base member and a cylindrical holding member. The telescopic base member is removably inserted into a cup holder of the vehicle. The telescopic base member is configured to vertically extend and retract to suitably position the cylindrical holding member. The cylindrical holding member is rotatably attached to the telescopic base member and comprises sidewalls and an opening. The opening is configured in the sidewall of the cylindrical holding member to accommodate a handle of the receptacle. The cylindrical holding member is divided into four sections, each section comprising a ribbed guide rail configured on the base of the cylindrical holding member for radial adjustments to secure receptacles of varied base dimensions. Further, release tabs are provided on an exterior surface of each of the four sections to release the secured receptacle.
US10562429B2 Beverage cooler and heater assembly
According to some embodiments, a beverage heating and cooling assembly is provided which includes a collar and beverage retainer assembly for connection to retain the assembly below a mounting substrate. The beverage retainer assembly may include a housing with an active heating or cooling system, such as a thermoelectric engine, which is positioned within or adjacent to the housing and beneath the mounting substrate or similar planar structure. The assembly allows for a clean installation of an active thermal system for beverages in order to keep the beverages cold or warm as desired.
US10562425B2 Adjustment device for a headrest of a vehicle seat
An adjusting apparatus for adjusting a vehicle seat component of a vehicle seat comprises an adjustment arrangement for adjusting the vehicle seat component and a locking device. The locking device is coupled to the adjustment arrangement to block movement of the vehicle seat component in a locking position.
US10562424B2 Armrest
An armrest has a base, a support arm pivotal on the base between a first end position and a second end position, and a latch including a first latch formation on the support arm and a second latch formation on the base for securing the support arm relative to the base in at least one of the end positions. A spring biases the support arm into the first end position and carries one of the first and second latch formations.
US10562419B2 Child's booster seat
A child's booster seat is provided and can include a booster seat base and seat back. The booster seat base can be collapsed or folded from an in-use configuration to a collapsed configuration to improve portability of the booster seat base. The booster seat base can include multiple seating surface panels that are rotatably coupled to one another to allow the booster seat base to be collapsed from an in-use width to a collapsed width that is less than the in-use width. The booster seat base can also be coupled and decoupled from the booster seat back. The booster seat base can include tab members that can be inserted into tab receiving cavities of the booster seat back. Adjustment of the booster seat base from the in-use configuration to the collapsed configuration can also facilitate removal of the tab members from the tab receiving cavities of the booster seat back.
US10562417B2 Reclining seat assembly having tension reacting member
A reclining seat assembly comprises a lower seating structure having an inboard side and an outboard side and a seatback pivotally affixed to the lower seating structure, the seatback having an inboard side and an outboard side. A gear system operatively couples one of the inboard side or the outboard side of the seatback to the corresponding inboard side or outboard side of the lower seating structure. The gear system operatively rotates the seatback relative to the lower seating structure. An actuator is coupled to the gear system to move the seatback between angular positions. A metal rod extends between the inboard side and outboard side of the seatback and has an inboard end and an outboard end. A threaded fastener assembly operably couples the inboard end and the outboard end of the metal rod to the inboard side and the outboard side of the seatback.
US10562416B2 Lifter device
A lifter device including: an input member configured to be rotated about a rotation shaft in synchronization with an operation handle and to input an operation force of the operation handle to a rotation drive mechanism and a lock mechanism; and a fixing member slidably fixing the input member to a support member rotatably supporting the rotation shaft.
US10562411B2 Sliding device
Provided is a sliding device. The sliding device includes a fixed rail, a movable rail, a rack, a pinion, a locking mechanism that restricts sliding of the movable rail, and a gear mechanism. The gear mechanism includes multiple gears and transmits a rotation generated in an electric motor to the pinion. The gear mechanism is configured such that the pinion is capable of rotating more than a specified angle of rotation when the electric motor is in a stopped state.
US10562405B2 Movable wireless charging system
A wireless charging station includes a movable charger having a primary coil and a controller having memory with a plurality of desired values for tire pressure sensor signal strength. The controller is programmed to position the primary coil relative to a secondary coil of a vehicle based on tire pressure signal strength values from the vehicle and the desired values.
US10562404B1 Integrated onboard chargers for plug-in electric vehicles
An onboard charger for both single-phase (level-1 and level-2, up to 19.2 kW) and three-phase (level-3, above 20 kW) charging of a battery in Plug-in Electric Vehicles (PEVs) is integrated with the Propulsion machine-Inverter Group residing in the PEV, and is controlled to operate in propulsion and battery charging modes. The subject integrated onboard charger provides battery charging at the rated power of the Propulsion machine, does not need motor/inverter rearrangement, does not require additional bulk add-on passive components, provides an effective input current ripple cancellation, and operates without rotation of the Propulsion machine during the steady state charging.
US10562402B2 Control system for hybrid vehicle
A control system for a hybrid vehicle that can reduce a power loss resulting from shifting an operating mode from motor mode to hybrid mode is provided. A transmission that is adapted to distribute torque applied to an input element to a reaction element and an output element, and to change a ratio between a first torque delivered to the reaction element and a second torque delivered to the output element. A controller is configured to start an engine in a high mode in which a torque ratio of the output element to the input element is small if the vehicle speed is higher than a threshold value, and to start the engine in a low mode in which the torque ratio is greater if the vehicle speed is lower than the threshold value.
US10562400B2 Steering system for in-wheel motor vehicle
The present invention provides a steering system for an in-wheel motor vehicle capable of controlling driving torques and speeds of in-wheel motors mounted in left and right wheels to be different from each other at the time of curve driving of the vehicle to generate a steering angle of the wheel for the curve driving, and performing a steering angle control of sensing the generated steering angle and fixing the steering angle to a desired steering angle.
US10562396B2 Parking assistance apparatus and system
A parking assistance system is provided which includes: a parking assistance apparatus that is installed along with a wireless power-supplying device and has a plurality of exciting coils installed around a power-supplying coil provided for the wireless power-supplying device and a plurality of resonators connected to the respective exciting coils and set to resonate due to leakage magnetic flux of the power-supplying coil; and a movable vehicle that detects magnetic flux generated by the exciting coils provided for the parking assistance apparatus, determines a position of the movable vehicle based on a result of the detection and displays the position on a display device.
US10562386B2 Motor vehicle having reduced engine movement caused by collision
A motor vehicle includes an engine assembly housed in a bay, a subframe adjacent a bottom of the bay, a bulkhead adjacent a rear of the bay, and a catch structure extending laterally across the bay above the subframe and adjacent an upper end of the bulkhead. A lower catch hook is coupled to the engine assembly and configured to engage the subframe and transfer load from the engine assembly to the subframe when the engine assembly moves toward the bulkhead during a collision. An upper catch hook is coupled to the engine assembly and configured to engage the catch structure and transfer load from the engine assembly to the catch structure when the engine assembly moves toward the bulkhead during the collision. The catch structure may be a cable connected to left and right suspension towers.
US10562385B2 Window assembly, window pane, and window sealing profile
A window assembly (170) for a window opening of a motor vehicle comprises a door frame member (22), a movable window pane (130), a window sealing profile (100), and a guiding bracket (150). The movable window pane (130) includes a guiding section (136) and a window section (131) having an outer window surface (132). The window sealing profile (100) is fastened to the door frame member (22) and includes a sealing portion (110, 111, 112, 120) for sealing the window pane (130) against moisture and/or noise. The guiding bracket (150) includes a trimming surface (155) and is configured to guide the window pane (130) along a direction of movement between an open position and a closed position, and vice versa. The guiding bracket (150) simultaneously engages the window sealing profile (100) and the window pane (130), when in the fastened state.
US10562384B2 Dual action truck bed cover
A dual action truck cover provides two modes, actions or ways to access contents in a truck bed. Side rails can be mountable to a cargo box so as to be pivotable between a raised position to provide a rear opening in an open pivot arrangement, and a lowered or closed pivot arrangement. The side rails can be spaced apart to define an inter-rail area therebetween. A door can include a plurality of elements hingedly coupled together and extending between the side rails and movable between a closed door arrangement wherein the elements cover the inter-rail area, and an open door arrangement in which the elements are positioned to permit access through the inter-rail area. The door can move between the open and closed arrangements by rolling up the hingedly coupled elements together or folding the elements together.
US10562381B2 Sliding door drive of a motor vehicle
The invention relates to a drive of a sliding door of a motor vehicle comprising an electric drive unit (2), a drive cable (10) and a guide (3) for the drive cable (10). Said drive unit (2), the drive cable (10) and the guide (3) are fixed in the vehicle body (K) and the sliding door can be moved by means of the drive cable (10) with respect to the vehicle body. At least one sub-assembly (33) of the guide (3) of the drive cable (10) is modular and the drive cable (10) can be deflected by the modular sub-assembly (33).
US10562380B2 Light weight removable body door system
A convertible vehicle door assembly includes a gate subassembly including an electrical panel, latch handle and is secured by hinges and a latch to a vehicle static structure. An outer door subassembly is removably secured to the gate subassembly by at least one quick connect mechanism. The outer door includes a window assembly operable by the electrical control panel.
US10562378B2 Shading device for vehicle
A shading device for a vehicle, comprising a dimming glass plate capable of changing a light transmittance thereof, wherein the dimming glass plate is provided at a portion of a vehicular window glass to separate an interior of vehicular compartment from outside or provided at a portion of a surface of the vehicular window glass that faces inside of the vehicular compartment; a display apparatus formed of a light transmitting material and disposed at a surface of the dimming glass plate that faces inside of the vehicular compartment; an image pickup device to capture an area outside of a vehicle to generate image pickup data, wherein the area is at an opposite surface of a surface on which the display apparatus is provided; a data processing circuit to generate display image data based on the image pickup data; and a switch to change light transmittance of the dimming glass plate.
US10562377B2 Battery life prediction and monitoring
A refrigeration system for a vehicle includes a compressor in fluid communication with a condenser and an evaporator. The compressor includes a variable speed motor and employs capacity modulation using refrigerant injection. The condenser and the evaporator include variable speed fans. The refrigeration system includes a battery to supply power to the refrigeration system. The battery is charged by one or more sources of power including the vehicle. The refrigeration system includes a control module configured to monitor one or more characteristics of the battery and to control one or more operating parameters of one or more of the compressor, the condenser, and the evaporator based on the one or more characteristics of the battery.
US10562376B2 Refrigeration cycle device
A refrigeration cycle device includes: a high-pressure side heat exchanger; a low-pressure side heat exchanger; a vehicle-mounted device that supplies heat to the heat medium; a heat-medium air heat exchanger that exchanges heat between the heat medium and air; a switching portion that switches between a state in which the heat medium circulates through the high-pressure side heat exchanger and a state in which the heat medium circulates through the low-pressure side heat exchanger with respect to each of the vehicle-mounted device and the heat-medium air heat exchanger; and a controller that drives the compressor, while controlling an operation of the switching portion to switch to a defrosting mode in which the heat medium circulates between the low-pressure side heat exchanger and the vehicle-mounted device, and the heat medium circulates between the high-pressure side heat exchanger and the heat-medium air heat exchanger, when defrosting of the heat-medium air heat exchanger is necessary.
US10562370B2 Heat pump system for vehicle
Disclosed herein is a heat pump system for a vehicle which includes an evaporator mounted on a cold air passageway inside an air-conditioning case, a condenser mounted on a warm air passageway, a first blower mounted at an inlet side of the cold air passageway of the air-conditioning case, a second blower mounted at an inlet side of the warm air passageway and an intake duct mounted between the first blower and the second blower to supply indoor air and outdoor air to the first blower and the second blower respectively, thereby maximizing space efficiency because using just one intake duct for the two blowers, and reducing the size and manufacturing costs of the heat pump system.
US10562368B2 Method and system for heating a passenger compartment of an electric vehicle, and electric vehicle implementing such a method or system
A method for heating the passenger compartment of an electric vehicle, including the following steps: pre-heating at least one part of the passenger compartment by at least one electric heater when the vehicle is connected to an external energy source, and heating the at least one part of the passenger compartment by a combustion heater when the vehicle is in use. Also provided is a system implementing such a method and an electric vehicle, in particular of the electric bus type, utilizing such a method or such a system.
US10562364B2 Vehicle wheel positioning and steering apparatus
A vehicle wheel positioning and steering apparatus particularly useful for aerial work platforms comprises a support chassis and chassis support legs pivotally connected to the chassis. Steerable wheel assemblies are operably connected at ends of the support legs and powered actuators are operably connected to the chassis and legs for pivotally moving the legs and wheel assemblies relative to the chassis between transport and working positions. Variable length linear wheel steering actuators comprise one link of four bar parallelogram steering linkages between the chassis and wheel assemblies and the support legs each comprise second bars of the four bar parallelogram steering linkages.
US10562363B2 Support unit
Support unit for use on an air spring, having a main body and a reinforcement element, wherein the main body has a first contact side for fixing to the chassis of a utility vehicle, wherein the reinforcement element is fixable to a second contact side of the main body and is designed for supporting a plunger of an air spring, wherein the reinforcement element is formed from a material of higher strength and/or hardness than the main body.
US10562362B2 Cage to cage locking mechanism
The present disclosure provides a system and method for securing the connection between drawbars of carts and hitches. The system and method involves limiting the drawbar's freedom to pivot once the drawbar is coupled to a hitch.
US10562360B2 Tread cover for a wheel
There is provided a traction cover for a wheel. The wheel has an axle, a tire, and a tire support that supports the tire, and the cover has a tread body having an inner engagement surface and an outer tread surface, the inner engagement surface being sized to engage an outer drive surface of the tire. The cover also has attachment points carried by the inner engagement surface of the tread body, an anchor secured relative to the tire support, and one or more attachment members attached between the anchor and the attachment points of the tread body.
US10562355B2 Tire bead
A tire for a motor vehicle having at least one carcass ply comprised of a crown portion and two axially opposite side portions terminating in beads for mounting the tire on a rim. A tread band and a belt structure are interposed between the carcass structure and the bead. Each bead includes on elongated cord comprised of a first yarn, such as aramid, having a melting or decomposition point T1, and a second yarn, such as nylon, having a melting point T2, wherein T1>T2, and T2 is greater than 40° C.
US10562354B2 Motorcycle tire for running on rough terrain
A motorcycle tire for running on rough terrain, the tire includes a tread portion including a central region, a pair of shoulder regions and a middle region. The tread portion is provided with at least one central block with a ground contact face whose centroid is located within the central region, at least one shoulder block with a ground contact face whose centroid is located within the shoulder region on each side of a tire equator, and at least one middle block with a ground contact face whose centroid is located within the middle region on each side of the tire equator. When the respective blocks are projected onto a tire meridian cross section along a circumferential direction of the tire, every pair of axially adjacent two blocks are arranged so as to overlap one another at least partially on the tire meridian cross section.
US10562347B2 Flexible wheel rim with floating hooks
Vehicle rim for the mounting of a tire, comprising: an axially central part (20) comprising a disc; two lateral parts (31, 32), at least one of the lateral parts being separate from the axially central part, each of the lateral parts having a rim seat receiving a bead of a tire, the axially central part and the two lateral parts being made from a rigid matrix reinforced by a plurality of reinforcement elements; an intermediate part (41, 42) linking the axially central part and each lateral part separate therefrom, this intermediate part being made of a flexible matrix reinforced by a reinforcement, wherein 1 MPa≤the Young's modulus of uniaxial extension of the flexible matrix≤100 MPa, the Young's modulus of uniaxial extension of the reinforcement elements is≥5 GPa; wherein the Young's modulus of uniaxial extension of the rigid matrix is≥5 GPa.
US10562345B2 Segmented wheel and method and system for controlling a segmented wheel
An adaptable wheel has a central hub, radial segments connected to the central hub at a proximal end and extending radially from the central hub, each radial segment having a linear actuator configured to change a length of the radial segment; a shoe connected to a distal end of the radial segment for contacting a surface being traversed by the wheel; and a locking mechanism for selectively preventing linear motion of the linear actuator. A control system for an adaptable wheel includes a distance sensor on a vehicle for determining distance to a surface in the path of the vehicle and a computer for receiving distance information from the distance sensor and, responsive to the distance information, determine a desired length of a segment of an adaptable wheel for maintaining a hub of a wheel level, and provide control signals to a linear actuator of the segment.
US10562344B1 Roller assemblies for a holonomic base
Holonomic bases, and drive shafts and roller assemblies that can be used in the holonomic bases. In some implementations, a holonomic base includes at least two pairs of roller assemblies, with each of the pairs being coupled to a corresponding drive shaft. In some of those implementations, each of the roller assemblies of each pair includes three roller segments that are each coupled to the corresponding drive shaft and that each include an exposed outward facing spherical zone that approximates a portion of the surface of a sphere. The roller segments of each roller assembly are in fixed relation to one another relative to the rotational axis of a drive shaft to which the roller assembly is coupled, but the roller segments each freely rotate about a corresponding roller segment rotational axis that extends outward from the drive shaft.
US10562339B2 Door skin, a method of etching a plate for forming a wood grain pattern in the door skin, and an etched plate formed therefrom
A door skin featuring a facing having an exterior surface and an interior surface can be provided. A wood grain pattern portion can be formed in the exterior surface of the facing. The wood grain pattern portion can feature a plurality of grooves formed in the exterior surface of the facing, the grooves are recessed from a first plane of the exterior surface, and tonal portions formed in the exterior surface of the facing. The tonal portions can include at least a first protrusion, a second protrusion, and a third protrusion. Spacing between the first protrusion and the second protrusion can be different from spacing between the second protrusion and the third protrusion.
US10562338B2 Heat pen for use with electronic cutting and/or drawing systems
A heat pen may be used with an electronic cutting and/or drawing system to enable the electronic cutting and/or drawing system to use heat to define text and/or designs on a substrate. The heat pen may be coupled with a cradle of an electronic cutting and/or drawing system directly or by assembling an adapter with the heat pen. Power may be supplied to the heat pen by electrically coupling the heat pen to an external power supply, such as a power and/or communications port of the electronic cutting and/or drawing system. Electronic heated design systems and methods for modifying substrates using heat are also disclosed.
US10562333B2 Article with curved patterns formed of aligned pigment flakes
In a printed article, pigment flakes are magnetically aligned so as to form curved patterns in a plurality of cross-sections normal a continuous imaginary line, wherein radii of the curved patterns increase along the imaginary line from the first point to the second point. When light is incident upon the aligned pigment flakes from a light source, light reflected from the aligned pattern forms a bright image which appears to gradually change its shape and move from one side of the continuous imaginary line to another side of the continuous imaginary line when the substrate is tilted with respect to the light source.
US10562332B2 Printable Medium Including Glitter
A printable glitter paper includes a first adhesive layer onto which glitter has been deposited, and a second adhesive layer covering the first adhesive layer and glitter. A coating covers the second adhesive layer. Another adhesive layer covers the back side of the printable glitter paper. The printable glitter paper provides excellent retention of the glitter, and a high level of smoothness for high quality printing.
US10562325B2 Liquid discharge apparatus
There is provided a liquid discharge apparatus including: a transporting unit that transports a medium in a transporting direction, a discharge portion that discharges a liquid to the medium positioned in a discharge range, and a supporting portion that has a first supporting surface and a second supporting surface, as a supporting surface supporting the medium to be transported by the transporting unit, in which the first supporting surface supports the medium in the discharge range and does not have unevenness in a width direction intersecting the transporting direction, the second supporting surface supports the medium on a downstream side of the discharge range in the transporting direction and includes uneven portions in which a first portion and a second portion which is further recessed than the first portion are formed alternately in the width direction.
US10562322B2 Print medium guides
An example assembly includes a first guide positioned in a pre-print zone area of an imaging device. A second guide rotatably is connected to the imaging device and spaced apart from the first guide to permit a print medium to traverse between the first guide and the second guide. A bearing mechanism connects the second guide to the imaging device in the pre-print zone area. An interface mechanism is operatively connected to the second guide. A bias element is positioned between the interface mechanism and the second guide to release energy upon exposing the interface mechanism to the pre-print zone area allowing rotation of the second guide away from the first guide.
US10562318B2 Method and system for compensating for a malfunctioning nozzle
Embodiments of the invention relate to techniques whereby sufficient compensation is provided to counteract the deleterious effects of a malfunctioning nozzle (i.e. which might create a white streak within the printed ink image) in a manner that is faithful to/harmonious with the underlying AM or FM screening. In this manner, it is possible to minimize the negative impact a failed or malfunctioning nozzle has upon the printed ink image.
US10562316B2 Printing apparatus and methods for detecting fluid levels
Printing apparatus and methods of detecting ink levels are disclosed in examples herein. An example printing cartridge includes a fluid container, a plurality of electrodes to detect fluid in the fluid container, and a shift register to capture fluid level information from the plurality of electrodes.
US10562314B2 Flow path member and liquid ejecting apparatus
A flow path member includes a filter, a first space provided with an entrance through which a ink flows in, and a second space separated from the first space by the filter and that has an exit through which the ink flows out and a bottom surface facing the filter, in which the bottom surface includes an inclined surface spaced away from the filter from an end of the filter toward a center in a case where the filter is viewed in plan view, and the exit is in a middle of the inclined surface.
US10562313B2 System for managing appropriateness of use of consumables for printing apparatus and method for managing appropriateness of use of consumables for printing apparatus
A bottle for ink supply is shipped with a two-dimensional code attached to the bottle, individual information being embedded in the two-dimensional code. A user reads the two-dimensional code with a portable information terminal and thereby transmits the individual information to a management server. If there is no fraud or problem, the management server transmits a passcode to the portable information terminal. When the bottle is placed in a bottle storing unit, the two-dimensional code is read by a two-dimensional code reader, and a passcode is created based on the individual information embedded in the two-dimensional code. Only when the passcode matches the passcode registered by the user, ink in the bottle becomes ready to use.
US10562312B2 Liquid ejecting apparatus
A liquid ejecting apparatus includes a liquid ejecting head which ejects a liquid from a nozzle onto a medium, a liquid storage member which stores the liquid to be supplied to the liquid ejecting head, and a carriage on which the liquid ejecting head and the liquid storage member are installed and which is capable of moving on a movement path. The liquid storage member includes a liquid filling port which is disposed above the liquid ejecting head and is for filling the liquid. The liquid filling port is provided at a position which does not overlap with a nozzle forming surface in which the nozzle is formed in plan view from above.
US10562310B2 Liquid container
In one example, a container includes expandable and contractible air free interior volumes joined by a passage through which liquid may pass from one volume to another volume, an inlet different from the passage through which liquid may enter into one of the volumes, and an outlet different from the passage through which liquid may leave another of the volumes.
US10562308B1 System and method for priming an ink delivery system in an inkjet printer
A jumper is configured to replace a printhead connected to an ink delivery system to enable a controller operating the ink delivery system to prime the ink supply conduit and the ink waste conduit of the ink delivery system. The jumper includes a pressure impedance element that simulates a pressure drop across the printhead when the printhead is connected to the ink delivery system. The jumper enables the ink supply conduit and the waste ink conduit to be primed with reduced risk of air being urged into the inkjets of the printhead once the printhead is reconnected to the ink delivery system.
US10562307B2 Printhead maintenance
Example methods for the maintenance of printheads are provided, the printheads comprising a reservoir containing a printing fluid with particles in suspension, and a nozzle plate. Example methods may comprise capping the nozzle plate of the printhead, and rotating the capped printhead. Example maintenance devices for printheads are also provided, comprising a support with a socket to attach a printhead to the support, a drive unit to rotate the support about a rotation axis, and a control unit connected to the drive unit to perform a predetermined rotation cycle.
US10562306B2 Method of manufacturing liquid ejection head
A liquid ejection head is manufactured by covering a mold material arranged on a patterned protecting layer on a substrate and subsequently removing the mold material to produce a flow path. A sacrificial layer employed as the mold material operates as mask for patterning the protecting layer.
US10562304B2 Noncircular inkjet nozzle
An inkjet nozzle includes an aperture with a noncircular opening substantially defined by a polynomial equation. A droplet generator is also described which includes a firing chamber fluidically coupled to a fluid reservoir a heating resistor and a nozzle. The nozzle includes an aperture forming a passage from the firing chamber to the exterior of the droplet generator through a top hat layer. The nozzle is defined by a closed polynomial and has a mathematically smooth and mathematically continuous shape around aperture's perimeter wall, with two protrusions extending into the center of the aperture.
US10562302B2 Liquid ejecting head, liquid ejecting apparatus, and piezoelectric device
A liquid ejecting head includes a flow path substrate in which a nozzle through which liquid is ejected, a pressure chamber that communicates with the nozzle and a liquid supply chamber that communicates with the pressure chamber are formed, a vibration plate that is installed on the flow path substrate and overlaps with the pressure chamber and the liquid supply chamber, and a piezoelectric element that is formed on the vibration plate on an opposite side from the pressure chamber, in which a portion of the vibration plate overlapping with the pressure chamber is thinner in a thickness than a portion of the vibration plate overlapping with the liquid supply chamber.
US10562300B2 Adaptive print head calibration process
Thermal inkjet printing wherein a printhead has ink ejection elements which are energizable by electrical pulses of a given energy with fire pulses of an amplitude (V) and a fire pulse width (fp). A printer controller sends commands to the printhead to spit ink drops, one or more temperature sensors coupled to the printhead measure a temperature of the printhead, and a calibration component coupled to the temperature sensor variably adjusts the fire pulse energy provided to the having ink ejection elements of the printhead. The calibration component initiates calibrating the printhead, spitting a number (X) of ink drops at a frequency (Y) by the electrical pulses, reading and storing printhead temperature, varying the fire pulse energy by repeating spitting ink drops and reading and storing printhead temperature, finding minimum temperature from the stored printhead temperatures, and deriving an operational fire pulse (fpop) from a fire pulse (fpon) that has produced the minimum temperature, wherein the printer controller uses the operational fire pulse (fpop) for printing.
US10562299B2 Printing apparatus
A drive signal generating unit generates a drive signal during a printing process including a first drive waveform for driving a discharger to discharge a liquid and a first micro-vibration waveform, and generates a drive signal during a discharging state determination process including a second drive waveform for driving the discharger to inspect the discharger, and a second micro-vibration waveform. The first drive waveform becomes a first potential during a first period, becomes a fourth potential during a second period, and becomes the first potential during a third period. The second drive waveform becomes a second potential during a fourth period, becomes a third potential during a fifth period, and becomes the second potential during a sixth period. The first micro-vibration waveform and the second micro-vibration waveform are different from each other.
US10562297B2 Ink-jet printer
There is provided an ink-jet printer comprising: a recording head, an electric power supply, and a controller which is configured: to determine an ink amount in which an ink is jetted by the recording head in a flushing processing; in a case that the determined ink amount is less than a first ink amount, to boost a driving voltage of the electric power supply to a target voltage value, in accordance with a predetermined first voltage boosting pattern; and in a case that the determined ink amount is not less than the first ink amount, to boost the driving voltage to the target voltage value, in accordance with a predetermined second voltage boosting pattern in which a voltage boosting time is shorter than that in the first voltage boosting pattern. Accordingly, it is possible to shorten FPOT while reducing the load on the constitutive elements of the ink-jet printer.
US10562294B2 Inkjet recording apparatus
An inkjet recording apparatus has a recording head, a thermal head, and a heat control portion. The recording head has an ink discharge surface. The thermal head is arranged opposite the ink discharge surface across a recording medium conveying passage and heats a recording medium. In the thermal head, a plurality of element arrays each formed of a plurality of heating elements arrayed in the recording medium conveying direction are provided in the width direction. The heat control portion makes at least part of the heating elements in the element arrays that correspond to the ink discharge ports that discharge ink generate heat.
US10562292B2 Method and device for applying a film
A method for applying a transfer ply of a foil to a substrate, with the steps of: a) applying a radically curable adhesive to at least one subregion of the transfer ply by means of an inkjet printhead; b) pre-curing the adhesive by UV irradiation; c) applying the at least one subregion of the transfer ply provided with adhesive to the substrate; d) fully curing the adhesive by UV irradiation; e) peeling a carrier ply of the foil from the at least one subregion of the transfer ply. An application apparatus and also printing apparatus for implementing such a method.
US10562291B2 Measured sensor distance correction
Example implementations relate to determining a correction factor that converts a measured sensor distance (228) to a calibrated sensor distance (222). The measured sensor distance may be based on an amount of substrate advancement through a web printing press (202) between detecting a mark (226-1, . . . , 226-N) on the substrate (204) at a first sensor (212) and detecting the mark at a second sensor (214). The calibrated sensor distance (222) may be the separation between the first sensor and the second sensor.
US10562286B2 Assembly and process for preparing affixing tape
This disclosure relates generally to an assembly and process for preparing affixing tape. The disclosure also relates to an affixing assembly and process using the prepared tape. The tape can be used, for example, to affix plastic items to mailing pieces. The assemblies and processes disclosed herein provide for added throughput, less down time, higher quality of parts and production control.
US10562279B2 High stable and environment-friendly two-layer parquet and production method thereof
The invention discloses a high stable and environment-friendly two-layer parquet and a production method thereof. The parquet comprises a face board and multiple solid wood boards below the face board, the solid wood boards comprise multiple solid wood strips inserted side by side; any adjacent two solid wood strips of the same solid wood board are arranged tightly and alternately, and the face board and solid wood boards are closely bonded with each other by an adhesive. The length directions of the solid wood strips of any adjacent two solid wood boards are vertical to each other; and the length direction of the solid wood strips of the solid wood boards at the two ends of the parquet is vertical to the length direction of the parquet. The invention can effectively reduce the use of high-quality solid wood, save the wood resources and has high stability and high strength.
US10562276B2 Interlayer film for laminated glass, and laminated glass
The present invention aims to provide an interlayer film for laminated glass which prevents a double image phenomenon in a specific area of laminated glass and enables display of high contrast images at a luminance within a certain range. The present invention also aims to provide a laminated glass including the interlayer film for laminated glass. The present invention relates to an interlayer film for laminated glass, having a multilayer structure including a luminescent layer and a resin layer on at least one surface of the luminescent layer. The luminescent layer contains a thermoplastic resin, a plasticizer, and a luminescent material. The resin layer contains a thermoplastic resin and a plasticizer. The interlayer film for laminated glass has a wedge-shaped cross-sectional shape. The luminescent layer has a difference between the maximum thickness and the minimum thickness of 100 μm or less.
US10562266B2 Adhesive, laminate, cell case packaging, cell, high-alkali solution packaging, alcohol-containing solution packaging, and package
An adhesive includes a modified olefin polymer (A) allowing a polymer of a C2 to C20 α-olefin having a structural unit derived from a C4 to C20 α-olefin to be modified with a monomer having a functional group capable of reacting with an isocyanate group and having a heat of fusion measured in accordance with JIS K7122 of 0 J/g or more and 50 J/g or less and a polyisocyanate (B).
US10562264B2 Waterproof moisture-permeable fabric and infection protective garment
An object of the present invention is to provide a waterproof moisture-permeable fabric suppressed in appearance abnormality and deterioration in barrier properties. A waterproof moisture-permeable fabric including a protective layer and a polyethylene microporous film that are stacked on each other with a synthetic rubber-based hot-melt adhesive, an olefinic hot-melt adhesive, or a composite hot-melt adhesive interposed therebetween, having a nonpolar oil content of 2 g/m2 or less, and a polar oil content of 0.01 g/m2 or more and 6 g/m2 or less.
US10562258B2 Polymeric rule die, and formulations therefor
Die and counter-die systems, polymeric rule dies for such systems, and polymeric formulations suitable for producing such rule dies using digital rule writing. There is provided a rule die for pressure-contacting of a cardboard workpiece surface, including: (a) a die body; and (b) at least one elongate polymeric rule, each rule having: (i) a first elongate base surface adhesively attached to a surface of the die body; and (ii) an elongate protrusion, distally protruding from the die body, the elongate protrusion having an elongate die surface, the elongate die surface including a polymeric material, the elongate die surface having a contact surface adapted to contact the workpiece surface; the contact surface having a length of at least 5 mm and a first width (W) within a range of 0.4 to 1.0 mm, the rule having a height (H) within a range of 1.0 to 4.5 mm; wherein, over a total length of the contact surface, the contact surface having at most 5 surface pocks/meter, the pocks having a diameter above 0.1 mm.
US10562257B2 Method for producing a paper roll with smooth plies and relative roll
A method for producing a paper roll by conveying a first smooth ply between an upper embossing roll with first projections defining a decorative motif, and a glue distribution or cliché roll; maintaining the cliché roll side by side to the upper embossing roll, the first ply interposed between the upper embossing roll and the cliché roll and subjected to incisions and to glue deposits at the first projections on one side of the first ply facing towards the upper embossing roll and on the opposite side of the first ply facing towards the cliché roll; conveying a second ply between the upper embossing roll and a coupling or marriage roll; maintaining the marriage roll side by side to the upper embossing roll by exerting a coupling pressure to perform the final coupling between the first ply and the second ply at the glue deposits forming a multilayer paper.
US10562254B2 Method of operating a handheld pressing unit
A method of operating a motor-actuated handheld pressing unit includes actuating a switch to initiate a pressing operation whereby one or more pressing jaws are moved from a starting position to a closed pressing position; automatically releasing the one or more pressing jaws by using a pressing piston when a prescribed pressing force has been reached, the pressing piston being actuated hydraulically by a hydraulic medium; and checking the reaching of the prescribed pressing force by using a pressure sensor to detect the pressure of the hydraulic medium. In an embodiment, the release of the pressing jaws may be interrupted. In an embodiment, a motor moves the jaws from the starting position to the closed pressing position. In an embodiment, the pressing force is continuously measured on intervals of less than one second.
US10562245B2 Method of manufacturing tank
It is possible to achieve reduction in the occurrence of tension decrease at fiber bundles in a sheet. A method of manufacturing a tank includes several steps. A feed step is carried out of feeding a sheet including aligned fiber bundles while applying tension to the sheet in the longitudinal directions of the fiber bundles. The method further includes a detection step of detecting a decreased tension part subjected to tension decrease in the sheet being fed and a tension recovery step of compensating for the tension decrease at the decreased tension part by spraying an organic solvent if the decreased tension part is detected in the detection step. The method also includes a winding step of winding the sheet having been fed on a liner.
US10562219B2 Cyclic-diene additives in polyethylene films and enhanced film orientation balance in production thereof
A method of forming a blown film comprising extruding a molten composition through a die opening to form a film; wherein the molten composition comprises at least one polyethylene and within the range from 0.10 wt % to 10 wt % of a cyclic-diene terpolymer by weight of the composition; causing the film to progress in a direction away from the die opening; cooling the film at a distance from the die opening, the distance adjusted to effect the properties of the film; and isolating a blown film therefrom.
US10562218B2 Method for setting up a molding system
The present disclosure provides a method for operating a molding system. The molding system includes a molding machine and a mold disposed on the molding machine, wherein the mold has a mold cavity for being filled with a molding material from the molding machine. The method comprises a step of obtaining a predetermined state waveform expressing a predetermined volumetric variation of the molding material. Next, the method further comprises obtaining a measured pressure and a measured temperature of the molding material in the mold cavity while performing a molding process for filling the molding material into the mold cavity. Next, the method includes obtaining a detected volumetric property of the molding material corresponding to the measured pressure and the measured temperature. Subsequently, the method comprises displaying the detected volumetric property of the molding material with the predetermined state waveform.
US10562216B2 Injection mold and device for preparation of light guide plate
An injection mold and a device for preparation of a light guide plate are provided by embodiments of the present disclosure. An injection mold, comprising a male mold and a female mold which cooperate with each other to define collectively a molding cavity adapted for molding a sheet component therein; a blowing device is provided in the male mold and configured to blow out gas with a predetermined pressure towards a bottom surface of the sheet component molded in the molding cavity to overcome at least partially a vacuum adsorption force between the bottom surface of the sheet component and an internal bottom surface of the molding cavity such that the sheet component is separated from the male mold. Therefore, the sheet component can be demoulded successfully and prevented from a relatively large warping deformation during a demoulding process such that the quality thereof can be guaranteed.
US10562215B2 Water jacket spacer production method
A resin material is injection-molded using an injection mold in which a resin flow channel is designed so that a plurality of gates are provided along a longitudinal direction at a position corresponding to an inner circumferential surface of a spacer, to obtain a molded product, the spacer having a shape that a plurality of arc-shaped circumferential surfaces are linked through a constricted part. The molded product is cooled in a state in which a runner that is connected to the gates is allowed to remain, and the runner is cut off thereafter. A water jacket spacer is produced by injection molding while achieving excellent moldability, the water jacket spacer being disposed in a water jacket, and controlling the flow of a coolant, the water jacket spacer including a plurality of segments, or having a shape that the water jacket spacer can be partially inserted into the water jacket.
US10562213B2 Device for producing injection molded body and method of producing the same
The present invention addresses the problem of manufacturing first and second members with different materials when molding injection molding body one after another using first to third molds disposed at 120 degrees from each other on a turntable that performs reciprocating motion at 120 degrees and using fourth to sixth molds provided opposite to the first to third molds, respectively. According to the solution, first to third injection devices are disposed on the sides of fourth to sixth molds, respectively, the first injection device is caused to perform primary injection to mold a first member, and the second and third injection devices are caused to perform primary injection to mold a second member and secondary injection to integrate the first and second members with each other, whereby the first and second members can be manufactured with different materials one after another.
US10562212B2 Process and apparatus to injection mold continuous lengths of hollow plastic articles
A method and apparatus for manufacturing continuous ribbed pipes of thermoplastic resin material comprises the following successive steps. A length of pipe is injection molded in a mold cavity between a collapsible male mold element and female mold elements, the latter being shaped to provide integral ribbing on the outer surface of the pipe. After sufficient setting, the female mold elements are disengaged and the male mold element is collapsed and disengaged. A plunger then pushes the pipe length axially along the male mold element. The female mold elements and the collapsed male mold element are then re-engaged such that the one end of the formed pipe forms a closure for the mold cavity at the downstream end. Further material is again injected into the cavity which fuses with the one pipe end and which forms a further pipe length. These steps are repeated until the desired length of pipe is formed.
US10562207B2 Wafer processing method
A wafer processing method includes: a holding step of holding a wafer on a chuck table through a dicing tape; and a dividing step of cutting the wafer along division lines by a cutting blade. In the dividing step, cleaning water including pure water mixed with carbon dioxide is supplied to the front surface of the wafer, and cutting water including pure water alone or pure water mixed with carbon dioxide in a concentration lower than that of the cleaning water is supplied to the cutting blade. During cutting, therefore, the cleaning water and the cutting water are always shielded by each other. Consequently, the cutting blade can be prevented from being corroded or excessively worn due to the cleaning water, and the cutting water can be prevented from contacting the front surface of the wafer to cause electrostatic discharge damage to the devices.
US10562206B2 Cementitious panels, and systems and methods for manufacturing cementitious panels
The present disclosure embraces cementitious panels, and systems and methods of manufacturing cementitious panels. An exemplary cementitious panel includes a cementitious core material, a plurality of sheets of facing material surrounding the cementitious core material, and a radiation-cured adhesive. An exemplary method of manufacturing a cementitious panel includes conveying a slurry of cementitious core material and a plurality of sheets of facing material, applying a radiation-curable adhesive to at least one of the sheets of facing material, forming a continuous length of cementitious panel material, at least partly curing the radiation-curable adhesive with one or more beams of radiation emitting from one or more radiation-emitting devices, and cutting the continuous length of cementitious panel material laterally to a desired length, providing a cementitious panel.
US10562202B2 System and method of post-cure processing of composite core
A method of cutting a wafer of composite core from a bulk composite core includes stabilizing the bulk composite core with a fixture, the bulk composite core having a plurality of tube members. The method also includes cutting through each of the tube members to create the wafer while the bulk composite core is stabilized by the fixture.
US10562200B2 Polymeric cutting edge structures and method of manufacturing polymeric cutting edge structures
A functional polymeric cutting edge structure and methods for the manufacturing of cutting edge structures comprised of polymeric materials are provided. The cutting edge structures may be produced on a substrate having a blade body or blade support type. The polymeric material is produced by curing a precursor material by electromagnetic radiation wherein a wavelength of said radiation is about double a wavelength required to cure the precursor material. A razor blade for use in a razor cartridge or a blade box may be formed using the present invention.
US10562199B2 Connecting member
A novel connecting member of razor is shown to have a plurality of chamfers on at least one finger disposed at an end of an arm. Desirably, both arms have two chamfers on each finger. Each chamfer is disposed having an angle to a top surface of the finger. Though any angles are contemplated in the present invention, the angle of the first chamfer is desirably smaller than the angle of the second chamfer. The bearing length of the finger and the first chamfer angle are together desirably balanced to provide an optimal clearance for the fingers into openings on either end of the back of the housing and improve the pivot operation and control for the user.
US10562196B2 Robot, control device, and robot system
In a robot, each of a first flexible member and a second flexible member has a portion fixed to an n-th arm, a portion that is fixed to an (n+1)-th arm, and a portion that is positioned between the n-th arm and the (n+1)-th arm and is wound around a member in a folded state. The portion of the first flexible member that is fixed to the n-th arm is positioned on the member side from the portion of the second flexible member that is fixed to the n-th arm. The portion of the second flexible member that is fixed to the (n+1)-th arm is positioned on the member side from the portion of the first flexible member that is fixed to the (n+1)-th arm.
US10562191B2 Method of controlling devices with sensation of applied force
The inventive technology eliminates the need for force sensors on a robotic manipulator while also improving feel by incorporating force sensors on the corresponding robotic input device. Position of the manipulator is used to determine positioning of the input device; therefore, rather than manipulator position lagging the input device position (as in conventional robotic systems), the opposite is true, so that input device position lags manipulator position. Through a combination of input device force control and manipulator position feedback, a sense of feel is achieved through use of an “effort sensor” mounted at a “control point” on the input device and use of a “position feedback force control” scheme.
US10562189B1 Automated package registration systems, devices, and methods
A method of operating a package handling system includes: receiving first image data representative of a first surface image of a package surface; identifying a pair of intersecting edges for the package surface based on the first image; determining a minimum viable region based on the pair of edges, the minimum viable region for gripping and lifting the package; receiving second image data representative of the package after the lift; and creating registration data based on the third image data.
US10562188B1 Automated package registration systems, devices, and methods
A method of operating a package handling system includes: receiving first image data representative of a first surface image of a package surface; identifying a pair of intersecting edges for the package surface based on the first image; determining a minimum viable region based on the pair of edges, the minimum viable region for gripping and lifting the package; receiving second image data representative of the package after the lift; and creating registration data based on the third image data.
US10562186B1 Method and control system for verifying and updating camera calibration for robot control
A robot control system and a method for camera calibration verification is presented. The robot control system is configured to perform a first camera calibration, and to control a robot arm to move a verification symbol to a reference location. The robot control system further receives, from a camera, a reference image of the verification symbol, and determines a reference image coordinate for the verification symbol. The robot control system further controls the robot arm to move the verification symbol to the reference location again during an idle period, receives an additional image of the verification symbol, and determines a verification image coordinate. The robot control system determines a deviation parameter value based the reference image coordinate and the verification image coordinate, and whether the deviation parameter value exceeds a defined threshold, and performs a second camera calibration if the threshold is exceeded.
US10562181B2 Determining and utilizing corrections to robot actions
Methods, apparatus, and computer-readable media for determining and utilizing human corrections to robot actions. In some implementations, in response to determining a human correction of a robot action, a correction instance is generated that includes sensor data, captured by one or more sensors of the robot, that is relevant to the corrected action. The correction instance can further include determined incorrect parameter(s) utilized in performing the robot action and/or correction information that is based on the human correction. The correction instance can be utilized to generate training example(s) for training one or model(s), such as neural network model(s), corresponding to those used in determining the incorrect parameter(s). In various implementations, the training is based on correction instances from multiple robots. After a revised version of a model is generated, the revised version can thereafter be utilized by one or more of the multiple robots.
US10562180B2 Fluidic robotic actuator system and method
A fluidic robotic actuator configured to assume at least a neutral position, the fluidic robotic actuator includes a first and second plate defining respective planar portions that are disposed in parallel planes in the neutral position. The fluidic robotic actuator also includes a plurality of elongated bellows extending between the first and second plates, the bellows each having a central main axis that is parallel to the central main axis of the other bellows in the neutral position, the main axis of the bellows being perpendicular to the parallel planes of the first and second plates in the neutral position, the bellows being coupled to the first and second plates at respective first and second ends of the bellows.
US10562179B2 Articulated shaft structure of robot and robot
The articulated shaft structure includes: a first joint member; a second joint member supported rotatable about a first axis; a ring-like output hypoid gear fixed to the second joint member coaxially with the first axis; a gear assembly attached to the first joint member; and a motor, wherein the gear assembly includes a housing member, an input hypoid gear, and gears, the housing member including a second joining surface fixed to a first joining surface, the input hypoid gear being supported by the housing member rotatable about a second axis, the gears decelerating rotation of the motor and transmitting the rotation to the input hypoid gear, the first joining surface is parallel to the first axis, the second joining surface is perpendicular to the second axis, and the bolt is fastened radially outside of the gears of all kinds assumed to be used, the kinds being defined by reduction ratios.
US10562178B2 Machine for beauty salon
A device for automating the process of installing eyelash extensions onto the natural eyelashes of a subject with an option of additionally painting the nails of a subject. In some embodiments, the placing of extensions is carried out by a robotic mechanism utilizing computer vision, and in some embodiments, a barrier is created between the robotic mechanism and said subject in order to protect them in the event of a malfunction.
US10562174B2 Workbench
A workbench includes a work support structure, a first leg member, a second leg member, a handle; and a rack and pinion system coupling the first leg, the second leg, and the handle. Moving the handle relative to the work support structure causes both the first leg member and the second leg member to extend from or retract into the work support structure via movement in the rack and pinion system.
US10562168B2 Handheld power tool
A handheld power tool includes at least one housing unit, at least one tool receptacle, at least one operating unit that has at least one operating element, and at least one electrical and/or electronic indication unit. The indication unit has at least one at least partially circumferentially arranged indication element that is configured to indicate at least one handheld power tool characteristic variable. The indication element in one embodiment is arranged on the housing unit in a region between the operating element the tool receptacle The indication element in another embodiment is arranged at least substantially adjacent to the operating element.
US10562158B1 Self-locking fastener system and process
A threaded fastener, inserted into a hole in materials to be joined, receives a free-running collar (nut) with out-of-round duplex barrels. Spring-loaded twin sockets cradle the barrels and a restraining polygon key extends through the sockets and into a recess in the small face on the pin tail. Installation advances in tandem sequence; tightening before swaging. A machined groove with flat bottom and side rising at about 20 degrees from axial forms a boundary and partly reshapes crests from parallel to angular. Such inclination keeps the collar connected to the cavity of the larger of twin sockets throughout tangential tightening, rise of torque, displacement of crest material, recoil of the smaller socket on the end barrel, cessation of collar rotation and plunging torque. When recoil ends, radial torque on the smaller socket crushes and locks barrel material into underlying left hand helical troughs that interrupt the last few pin threads.
US10562156B2 Ergonomic quick release mechanism for hand-held clamping toggle lock tools
Embodiments disclosed herein provide an ergonomic quick release mechanism for hand-held clamping toggle lock tools where a fixed jaw and handle have another jaw movably attached. A moving handle assembly comprises a front handle section and a rear handle section held rigid to one another by a movable release trigger mounted on one of the two sections engaging a catch on the other section. The front handle section connects to the movable jaw and a toggle link. Squeezing the moving handle causes the jaws to close and a toggle pivot to go past toggle over center, locking the jaws. To unlock them, the release trigger is disengaged and the rear handle section is then squeezed causing it to rotate and contact an element of the fixed handle assembly at a release fulcrum point, causing the front handle section to rotate outward, releasing the toggle lock.
US10562154B2 Cutting blade
Disclosed herein is a cutting blade including diamond abrasive grains and boron compound grains. The average grain size of the diamond abrasive grains falls within the range of 5 μm to 50 μm. The average grain size of the boron compound grains is greater than ⅕ and less than or equal to ½ of the average grain size of the diamond abrasive grains.
US10562152B2 Method for modifying the appearance of a surface
A process for modifying the appearance of a surface is provided. The process includes a stage of spraying particles exhibiting a maximum size of less than or equal to 500 μm. The sprayed particles exhibit a relative density of greater than 90%, more than 5% and less than 80% by volume of the sprayed particles being particles exhibiting a salient sharp edge. The salient sharp edge is referred to as “notching particles”.
US10562151B2 Slurry supply and/or chemical blend supply apparatuses, processes, methods of use and methods of manufacture
A slurry and/or chemical blend supply apparatus suitable for providing slurry and/or chemical blend to chemical mechanical planarization (CMP) tools or other tools in a semiconductor fabrication facility, related processes, methods of use and methods of manufacture. The slurry and/or chemical blend supply apparatus includes one or more of the following: feed module, blend module, analytical module and distribution module.
US10562149B2 Polyurethane CMP pads having a high modulus ratio
A chemical-mechanical polishing pad comprising a polyurethane polishing layer having a high storage modulus at low temperatures and a low storage modulus at high temperatures is disclosed. For example, the disclosed pad embodiments may be fabricated from a thermoplastic polyurethane having a ratio of storage modulus at 25 degrees C. to storage modulus at 80 degrees C. of 50 or more. The thermoplastic polyurethane polishing layer may further optionally have a Shore D hardness of 70 or more, a tensile elongation of 320 percent or less, a storage modulus at 25 degrees C. of 1200 MPa or more, and/or a storage modulus at 80 degrees C. of 15 MPa or less.
US10562146B2 Fiber based finishing tools
A finishing tool for modifying a surface of a part, including: a base, wherein the base is one or more of rotated and translated; and one or more fibers coupled to the base; wherein a base portion of each of the one or more fibers is disposed at a first angle relative to a major axis of the base, wherein the first angle is equal to or between −90 degrees and 90 degrees; and wherein, in operation, an end portion of each of the one or more fibers is disposed at a second angle relative to the major axis of the base, wherein the second angle is approximately −90 degrees or 90 degrees, substantially parallel to the surface of the part. In operation, the base portion and the end portion of each of the one or more fibers is coupled by a continuously curved intermediate portion.
US10562142B2 Pallet changing apparatus
A pallet changing apparatus which adopts a table 4 that is able to move back and forth in relation to a turning shaft 1 and has a oscillating portion 41 for placing workpieces W, W′ by way of pallets P, P′ so as to oscillate freely by a rising portion 42 at the leading end of the table, and a bridging extending portion 31 which bridges a supporting portion of pallet P or P′ in a pallet changing arm 3 with both sides of the turning shaft 1 forming a shape of covering across the upper side of the rising portion 42 at a stage of the table 4 transferring pallet P.
US10562129B2 Method for bonding steel material and device for bonding steel material
First steel material, a carbon sheet, and second steel material are put in a state of being separated from each other, and bonding parts are heated by, for example, applying current from a power supply to the carbon sheet. Alternatively, the bonding parts may be heated by an inductive heating coil. Thereafter, heating is terminated if the bonding parts reaching greater than or equal to the eutectic point and less than the liquidus line temperature is detected in the Fe—C phase diagram. Furthermore, the carbon sheet is made to be sandwiched between the first steel material and the second steel material.
US10562123B2 Welding system with arc control
A method and apparatus for controlling arc/short between a wire and a work piece is described. A current path parallel to the wire/work is provided. The voltage drop across the parallel path can be preset, to limit the wire/work voltage, or it can be controlled to a desired level. The control can be in response to feedback.
US10562119B2 Machining system and tool holding apparatus thereof
A machining system for electromachining a workpiece that in one embodiment includes a machine tool, a cutting tool for performing the eletromachining, and a tool holding apparatus for conductively holding the cutting tool and coupled to the machine tool. The tool holding apparatus includes a holding element for holding the cutting tool and at least one solution releasing element. The solution releasing element is used to receive machining solution and release the machining solution onto a predetermined area of the cutting tool through at least one group of channels. Each group of channels includes at least two channels configured to respectively release the machining solution onto at least two adjacent sections in the predetermined area of the cutting tool.
US10562118B2 Tapered pipe thread-machining spiral tap
A pipe-tapered-thread machining spiral tap includes a tapered thread portion that is circumferentially divided by flutes into a plurality of lands. Each of at least one of the lands has a cutting edge that extends along a corresponding one of the flutes. The flutes are made of a plurality of spiral flutes that are three, four or five spiral flutes each having a helix angle that is not smaller than 30° and smaller than 50°. A flute width ratio AG/(AG+AL) is 0.3-0.5, where AG represents a central angle which is subtended by each of the flutes and which is defined at a center corresponding to the rotation axis in a cross section that is perpendicular to the rotation axis, and AL represents a central angle which is subtended by each of the lands and which is defined at the center in the cross section.
US10562117B2 Cutting apparatus including a liquid spray system
A cutting apparatus and the method of operating same is provided. The apparatus includes a feed tower assembly configured to be attached to an object and a frame assembly movably attached thereto. The frame assembly has arm assemblies thereon which accept a cutting member. A liquid spray system is provided for cooling components of the cutting apparatus.
US10562115B2 Electric power tool and method for manufacturing the same
A covering member made of a resin is integrally molded with a sensor substrate of a brushless motor in a circular saw by low-temperature, low-pressure injection molding. The covering member covers rotation detecting elements, a thermistor, resistors, and connecting portions (terminals) of lead wires that serve as electrically conductive portions conducting electric currents.
US10562112B2 Method for processing sputtering target and method for manufacturing sputtering target product
Disclosed is a method for processing a sputtering target comprises: processing a sputtering target by rotating a cutting tool which has a blade portion with an arc-shaped concave curved surface on a cross section along the axis, around an axis thereof, to chamfer the target at a corner portion between a sputtering surface and a side surface in the sputtering target with an arc-shaped concave curved surface of a blade portion in such a manner that the corner portion is approximated to an arc-shaped aimed R face, wherein the sputtering target is chamfered at the corner portion in such a manner that a curvature radius Ra of the concave curved surface in the blade portion is equal to or more than a curvature radius Rb of the aimed R face on the cross section along the axis and that both ends of the concave curved surface in the blade portion are positioned away from the sputtering target.
US10562108B2 Self-centering drill bit
A cutting tool is provided that is operable to provide a circular cut or hole in a material or work piece. In various embodiments, a guide member is provided that facilitates alignment of a cutting edge of the invention with a pre-existing cut, hole or aperture. Devices and methods of the present disclosure provide for quick and easy centering of a cutting tool in order to form an enlarged hole that is concentric with a pre-existing hole.
US10562105B1 Automotive wheel CNC (computed numerical control) lathe
The present invention is a novel machine for repairing damaged wheel rims whereby the machine is a combination CNC and manual lathe configured of performing all of the required tasks for repairing damaged wheel rims in a single unit.
US10562103B2 Method of making iron nitride powder with anisotropic shape
Techniques are disclosed for milling an iron-containing raw material in the presence of a nitrogen source to generate anisotropically shaped particles that include iron nitride and have an aspect ratio of at least 1.4. Techniques for nitridizing an anisotropic particle including iron, and annealing an anisotropic particle including iron nitride to form at least one a″-Fe16N2 phase domain within the anisotropic particle including iron nitride also are disclosed. In addition, techniques for aligning and joining anisotropic particles to form a bulk material including iron nitride, such as a bulk permanent magnet including at least one a″-Fe16N2 phase domain, are described. Milling apparatuses utilizing elongated bars, an electric field, and a magnetic field also are disclosed.
US10562099B2 Gradient material control and programming of additive manufacturing processes
Aspects of the present disclosure relate to. In one example, a method of controlling an additive manufacturing machine includes: determining a material transition between a first machine control code and a second machine control code in a set of machine control codes; determining a material transition time for the determined material transition between the first machine control code and the second machine control code; determining a motion time from the first machine control code and the second machine control code; comparing the material transition time to the motion time; and manipulating the set of machine control codes based on the comparison.
US10562092B2 Tool for hot stamping and method for making the tool
A tool for hot stamping metal sheets, formed least partially of a base block and a functional layer, is proposed. The functional layer comprises cooling channels and multiple functional layers, which building upon each other create the connection to the base block. The cooling channels are designed as a cooling channel array and are produced in a laser sintering method.
US10562085B2 Equipment line for manufacturing heavy-walled steel products
An equipment line for manufacturing heavy-walled steel products having excellent low-temperature toughness, the equipment line including a heating device, a cooling device, and a hot working device in this order. The working device includes plurality of hot working devices, and the cooling device is arranged on an entrance side of at least one of the plurality of hot working devices. Furthermore, a thermostat equipment is arranged on an exit side of the hot working device. The equipment line provides a steel product with a finer microstructure with a relatively small amount of working.
US10562082B2 Method for contamination prevention in fluid storage tank requiring temperature control, and device therefor
A method is disclosed herein for detecting cracks of a fluid storage tank due to breakage of a wall of the fluid storage tank. In an example embodiment, the method includes positioning an enclosed pressure-resistant jacket around an outer wall of the fluid storage tank, controlling a temperature of the fluid in the fluid storage tank by allowing a liquid cooling or heating medium to flow in the enclosed pressure-resistant jacket at a pressure lower than a pressure x applied within the fluid storage tank, maintaining the pressure in the pressure-resistant jacket lower than the pressure x, sampling the cooling or heating medium from an air pool provided in a passage of the cooling or heating medium, and analyzing components of the cooling or heating medium, while preventing contamination of the fluid in the fluid storage tank with the liquid cooling or heating medium.
US10562079B2 Supercritical-state cleaning system and methods
Disclosed is a supercritical-state cleaning system, comprising a cleaning chamber (4), a gas booster apparatus (11), a first heating apparatus (5), and a carbon dioxide supply apparatus. The cleaning chamber (4) is separately connected to the first heating apparatus (5) and the carbon dioxide supply apparatus. A vacuum pump set (1) is connected to the cleaning chamber (4). Compared with the prior art, in the Invention, air introduced when a workpiece enters a cleaning chamber is completely removed, so as to prevent mixing of CO2 and air, thereby improving a cleaning effect.
US10562077B2 System comprising a portable switching device for use with a portable electronic device
A lens and/or a view screen of an electronic device having at least one case can be cleaned by wiping the view screen with a cleaning component wherein the cleaning component is configured to selectively couple to the at least one case or some other substrate using a magnetic attractive force. The cleaning devices may have secondary applications such as securing fly fishing lures, activating or deactivating a device having a magnetic switch, or preventing sunglasses from sinking. They may also be manufactured without a cleaning component for use with the secondary applications.
US10562073B2 Apparatus for measuring the stiffness of mailpieces
Apparatus for measuring the stiffness of mail articles on the principle of measuring deflection of a beam in bending comprises a rectilinear conveying portion for conveying the mail articles, a deflection roller disposed in a staggered offset manner between two wheels having deformable rims in such a manner as to form a substantially triangular peak on the rectilinear conveying portion, and an inlet ramp that is disposed upstream from the peak and that follows the upward slope of the peak.
US10562071B2 System for structural health monitoring and/or non-invasive tank fluid level measurement including cryogenic and zero G environments
A system includes a first transducer configured as an actuator. The first transducer is in communication with a surface of a structure. A second transducer is configured as a sensor. The second transducer is in communication with the surface. A third transducer is configured as a sensor. The third transducer is in communication with the surface and separated from the second transduce by an area. A digitizing unit receives signals from the second transducer and the third transducer. The digitizing unit communicates a plurality of frequency signals for the first transducer. A computing unit communicates the plurality of frequency signals to the digitizing unit, receives digitized signals from the digitizing unit, and calculates a Frequency Response Function from the digitized signals. Changes to the Frequency Response Function indicate a change to physical properties of the structure.
US10562060B2 Compact nebulizer for freshening the air
Nebulization systems to generate a mist of microdroplets of a liquid for the purpose of refreshing the atmosphere. Such nebulization systems are sized for mounting on a sales display for humidifying and refreshing fresh products displayed for sale.
US10562059B2 Devices and methods for the controlled formation and dispension of small drops of highly viscous and/or non-newtonian liquids
A controlled-volume spray deposition system has a fluid feed system including a pair of bi-directional, counter-rotating rollers to dispense fluid as a first surface, the rollers operable to rotate in a first direction to dispense the fluid, a second surface positioned to receive the fluid when the rollers rotate in the first direction, and the rollers operable to rotate in a second direction to retract the fluid to cause the fluid to stretch and form a filament until it breaks to form a spray. A method of generating a controlled-volume spray includes feeding fluid between two counter-rotating rollers as a first surface as they rotate in a first direction until the fluid contacts a second surface, reversing the counter-rotating rollers such that they pull the fluid to form a fluid filament, and causing the filament to break into a spray.
US10562055B2 Selective step coverage for micro-fabricated structures
A shadow mask having two or more levels of openings enables selective step coverage of micro-fabricated structures within a micro-optical bench device. The shadow mask includes a first opening within a top surface of the shadow mask and a second opening within the bottom surface of the shadow mask. The second opening is aligned with the first opening and has a second width less than a first width of the first opening. An overlap between the first opening and the second opening forms a hole within the shadow mask through which selective coating of micro-fabricated structures within the micro-optical bench device may occur.
US10562051B2 Powder hopper for difficult-to-flow powders for use in thermal spraying and method making and using the same
A hopper assembly includes a hopper configured to contain a feedstock material. A vibration imparting device is arranged inside the hopper and a vibration source coupled to the vibration imparting device. Embodiments of the instant invention are believed to provide various improvements in feeding uniformity by providing various hopper configurations that ensure a more consistently uniform filling of the metering device for a variety of difficult-to-feed materials and not-so-difficult-to-feed materials. One, more or all of these embodiments are also believed to improve accuracy and add precision to control, and, in addition, offer more simplified hopper construction—which is less costly to manufacture and maintain.
US10562049B2 Foam generating device for a high-pressure water gun
A foam generating device for a high-pressure water gun has a supporting body (14) defining part of a conduit (2), which extends along an axis (3) and has a mixing chamber (7) communicating with a lower inlet, and subject, in use, to a vacuum to aspirate a liquid from said lower inlet; the device has a first sleeve (17) which is fitted around one end of the supporting body (14), is axially fixed, is rotatable and is provided with an end portion carrying a nozzle (40); such a nozzle (40) defines the outlet (5) of the conduit and is adjustable so as to vary the outgoing flow type between a fan-like jet and a solid stream jet; the device has, in addition, a second sleeve (44) which is coupled to the first sleeve (17) in a fixed axial position and in a rotatable manner and is provided with cams (49) to adjust the nozzle (40) in response to a rotation of the second sleeve (44) with respect to the first sleeve (41).
US10562048B2 Electrohydrodynamic atomization nozzle emitting a liquid sheet
Embodiments for producing un-agglomerated, monodisperse droplets using a liquid sheet are provided. Nozzles with exit slit openings shape a spray liquid into a thin liquid sheet as the spray liquid exits from the slit opening. Stable multi-jet operation is achieved by including notches along the edge of the slit. The notches separate the liquid sheet into multiple jets to provide anchoring and stable multi jet operation. In some embodiments, the liquid sheet electrospray techniques and nozzles described herein provide high mass throughput and versatile multiplexing spray systems while reducing the engineering effort and high manufacturing cost.
US10562039B2 Automatic analysis device and separation and washing method
An automatic analysis device and method having a BF separation process, wherein the width in a container conveyance direction of a surface facing a reaction container of a magnet for preliminary magnetic collection of a first magnetic generation part (32p) is set to have a length including a region for housing a liquid sample of the reaction container conveyed to a magnetic collection position of the first magnetic generation part. An end in the container conveyance direction of a surface facing the reaction container of a magnet for regular magnetic collection of a second magnetic generation part (32m) is designed to be close to the center of the region for housing the liquid sample of the reaction container conveyed to a magnetic collection position of the second magnetic generation part.
US10562034B2 Roller mill and method for manufacturing roller mill
Provided is a roller mill that is provided with: a rotary table; a raw coal adding tube that supplies solid fuel to the rotary table; and a roller that rotates about a rotating shaft by being pressed against a grinding surface of the rotary table and grinds solid fuel along with rotation of the rotary table. In such a roller mill, a position where an outer peripheral surface of the roller and the grinding surface of the rotary table come into contact with each other and a circumferential velocity of the outer peripheral surface equals a circumferential velocity of the grinding surface is located further to an inner circumferential side of the rotary table than a position where the outer peripheral surface and the grinding surface come into contact with each other at a center position in a width direction of the roller.
US10562033B2 Smoking accessory assembly
A smoking accessory assembly facilitates storing and transporting accessories for grinding smoking matter and rolling the smoking matter for smoking. The assembly includes a housing having a plurality of compartments. A grinder has a plurality of grinder teeth and a peripheral wall enclosing the grinder teeth. A plurality of cap teeth is coupled to and extends from a top cap. The grinder is insertable into the top cap for grinding plant matter. A funnel tapers away to a tube section extending from a base of the funnel. Openings extend through the grinder for passing ground plant matter through the funnel and into the tube section. The tube section is open for passing the ground plant matter into a rolling paper wrapped around the tube section.
US10562031B2 Pipette tip trays
Provided are pipette tip trays for use in biotechnology applications. In certain embodiments, provided are pipette tip trays having one or more of the following features: (i) lacking an external hinge between the lid and the rack, and (ii) having snap plate fasteners configured to releasably secure a snap plate to a base.
US10562012B2 Process for the preparation of a catalyst and a process for producing glycols using the catalyst
A process for the preparation of a catalyst composition for catalysing hydrogenation and hydrogenolysis reactions wherein, (a) a carbon support is contacted with a catalyst precursor solution comprising at least one element from groups 7, 8, 9, 10 and 11 of 5 the periodic table to form a metal impregnated carbon; (b) the metal impregnated carbon is dried at a temperature of no greater than 400° C. and placed in a reactor vessel; (c) the reactor vessel is sealed; and (d) the metal impregnated carbon is treated in the reactor 10 vessel in an atmosphere comprising hydrogen at a temperature of from 25° C. to 350 ° C.
US10562010B2 Stratified charge combustion engine
The invention relates to an at least partly stratified (such as at least partly dual stratified) charge combustion engine, especially CAI (combustion assisted ignition), HCC, HCSI and HCCI engine, in which the combustion of a hydrocarbon containing fuel generating a flame emitting photon is operated in a chamber with a wall provided with a cerium oxide-carbon containing coating, said coating further comprising at least comprising oxides of the followings elements Pr, Nd, La and at least Y and/or Zr. The engine of the invention enables a catalytic reduction of NOx exhaust rate.
US10562007B2 Separation matrix
The present invention relates to a separation matrix, which comprises a support; extenders coupled to an outer part of said support; and ligands coupled to said extenders, wherein the part of the support to which the extenders are coupled constitutes less than 50% of the volume of the separation matrix. The invention also embraces a method of preparing such a separation matrix, as well as a process wherein the separation media is used.
US10562004B2 Method of fabricating cell arrays and uses thereof
The present disclosure provides a fabrication process that results in creating large arrays of living cells, such as stem cells, which are subsequently exposed to nanoliter quantities of compounds to test the efficacy on cellular metabolism.
US10562001B2 Adjustable lift engager
A lift engager for providing a stream of fluidized catalyst particles with an adjustable conduit and process using the lift engager. The lift engager includes a vessel with an inlet configured to receive catalyst from a reaction zone. A first conduit, within the vessel, is configured to supply lift gas into the lift engager. The first conduit includes a fixed member and a movable member secured to the fixed member and is configured to adjust a length of the first conduit within the vessel. A second conduit inside the first conduit and configured to provide fluidized catalyst to a regeneration zone.
US10561997B2 Mixing unit for mixing fluids
A mixing unit (100) for mixing of fluids is disclosed. The mixing unit (100) includes a mixing chamber (102) for holding one or more fluids and a driving assembly (104) operatively engaged to the mixing chamber (102). The driving assembly (104) is configured to oscillate the mixing chamber (102) for mixing the one or more fluids. The mixing chamber (102) of the mixing unit (100) enables better mixing of fluids in a convenient manner. Further less amount of cleaning fluids may be only required for cleaning the mixing chamber (102) after the mixing process. The mixing unit (100) can be used for mixing amino acids with different fluids however this unit can be used for mixing other fluids as well.
US10561992B2 Porous membrane and method of production thereof
The invention provides a porous membrane comprising polyvinyl chloride (PVC) and at least one inorganic filler embedded in the porous membrane wherein the inorganic filler comprises sulfuric acid precipitated silica. The invention further provides a process for the production of said porous membrane.
US10561991B2 Homogeneous anion-exchange composite membrane having excellent chemical resistance and method for producing the same
The present invention provides a anion-exchange composite membrane comprising a copolymer containing a vinylbenzyl trialkylammonium salt repeating unit, a styrene repeating unit and a divinylbenzene derived repeating unit; an olefin additive; a plasticizer; and a polyvinyl halide polymer. The anion-exchange composite membrane comprising a copolymer containing a vinylbenzyl trialkylammonium salt repeating unit, a styrene repeating unit and a divinylbenzene derived repeating unit; an olefin additive; a plasticizer; and polyvinylidene fluoride of the present invention not only displays low electrical resistance, excellent ion exchange capability, excellent ionic conductivity, excellent mechanical properties, excellent chemical properties, and processability, but also is easy to regulate its ion exchange capacity and ionic conductivity. Also, the composite membrane of the invention is easier to produce and cheaper to manufacture than the conventional anion-exchange composite membrane.
US10561982B2 Ammonia-based desulfurization process and apparatus
Apparatus and methods for desulfurization of a sulfur-oxide containing gas by treatment with ammonia containing liquids. The apparatus and methods may utilize two distinct circuits of two different ammonia containing liquids which are applied in two distinct chambers. The gas may be cooled prior to entry into the circuits. There may be fluid communication between the two circulation circuits.
US10561981B2 Wet desulfurization apparatus capable of improving desulfurization efficiency and wet desulfurization method using the same
A wet desulfurization apparatus includes a chamber enclosing a space for passing flue gas and including a first barrier partitioning the space into first and second chamber regions, a flue gas inlet to introduce raw flue gas into the first chamber region, and a flue gas outlet to discharge desulfurized flue gas from the second chamber region; a second barrier partitioning a slurry reservoir into a first reservoir part to store a first pH alkaline slurry and a second reservoir part to store a second pH alkaline slurry; a first sprayer to spray the alkaline slurry from the first reservoir part into the first chamber region to remove sulfur from the flue gas in the first chamber region; and a second sprayer to spray the alkaline slurry from the second reservoir part into the second chamber region to remove sulfur from the flue gas in the second chamber region.
US10561976B2 Carbon dioxide collecting apparatus and method using independent power generation means
A carbon dioxide capturing apparatus and process uses a self-generating power means that uses carbon dioxide in combustion exhaust gas through the convergence of a carbon dioxide absorption tower. The capturing apparatus and process also relies on ionic generator associated technology using a concentration difference between seawater and freshwater. The capturing apparatus and process result in increased production efficiency for electric energy and reduced costs for a carbon dioxide capturing process by increasing a concentration difference using an absorbent liquid for absorbing carbon dioxide and, at the same time, electricity is obtained through carbon dioxide which is a greenhouse gas.
US10561973B2 Element assembly and filter
A filter (10) has a port block (13) provided with: an inflow port (11) to which compressed air is supplied; and an outflow port (12) from which purified compressed air flows out. A filter container (14) is attached to the port block (13), and an element assembly (30) is disposed inside the filter element (31). The element assembly (30) has: a filter element (31); and an air guide member (41) provided inside the filter element (31). The compressed air filtered through the filter element (31) is guided to an inner surface of the air guide member (41) through a slit (46).
US10561971B2 Solid-liquid separator
A solid-liquid separator for separating a solid phase from a liquid phase in a solid-liquid mixture is provided. The solid-liquid separator includes a basket and filter assembly housed coaxially within a tank such that when the basket and filter assembly rotates the liquid phase moves through the filter of the basket and filter assembly into the tank and is discharged from the solid-liquid separator. The solid phase is retained on the filter of the basket and filter assembly and travels vertically up the filter of the basket and filter assembly where it is discharged from the solid-liquid separator.
US10561970B2 Filtration device
A filtration device has a primary conveyer tank which is equipped with a first conveyer, a primary drum filter which rotates inside the primary conveyer tank, a secondary conveyer tank which is equipped with a second conveyer and a secondary drum filter which rotates inside the secondary conveyer tank. Liquid in the primary conveyer tank passes through a first opening to flow into the secondary conveyer tank. Clean liquid flowing into a first clean tank is supplied to a low-pressure-side supply system by a first pump. Super-clean liquid having been filtered by the secondary drum filter passes through a second opening to flow into a second clean tank, and then is supplied to a high-pressure-side supply system by a second pump.
US10561969B2 Filter element having supporting elements, filter having a filter element, and filter housing of a filter
A filter element is provided with a filter bellows that has an inflow side and an outflow side for a fluid to be filtered, wherein the filter bellows is made of a zigzag-folded filter medium with folds with fold edges. The inflow side is defined by the fold edges of the folds of the zigzag-folded filter medium at the inflow side and the outflow side is defined by the fold edges of the folds of the zigzag-folded filter medium at the outflow side. At least one filter element holding device is provided that holds the filter element in a filter housing. The at least one filter element holding device is connected directly or indirectly with the filter bellows. At least one supporting element supports the filter element in the filter housing; the at least one supporting element is separate from the at least one filter element holding device.
US10561961B2 Fluid dispersion unit with directional component vector
A valve-tray assembly and method for lighter fluid heavier fluid contact towers. The active area of the tray is constructed with valves having multiple lighter fluid discharge areas facilitating improved mass transfer efficiency. The valves include first and second support legs oriented in line with the heavier fluid flow with both legs and the valve top constructed with apertures wherein the heavier fluid may flow into engagement with the lighter fluid passing from beneath the tray up, through and out of the valve.
US10561960B2 Method and apparatus for purifying water, potable spirits and essential oils
A distillation apparatus and method of more rapidly purifying water, potable spirits and essential oils and more specifically to a unique heat distribution device referred to herein as the flame flow that provides for the contents of the apparatus to reach evaporation temperatures more quickly and maintain temperature to provide better control and more evenly heat the contents of a distillation apparatus.
US10561959B1 Building block system
A building block system includes a block body having four side faces offset 90 degrees from an adjacent side face and having a side edge intermediate adjacent side faces. The block body includes a top face perpendicular to the side faces and a bottom face opposite and parallel to the top face that is perpendicular to the four side faces, the top and bottom faces having a plurality of upper and lower edges, respectively, intermediate the four side faces, respectively. The system includes a plurality of receiver members, a single receiver member being positioned on a respective the side edge and on a respective the upper edge and on a respective the bottom edge. The system includes a plurality of connector members positioned intermediate the plurality of receiver members, respectively. Each receiver member has a configuration operable to receive a respective connector member in a locking engagement.
US10561954B1 Methods for dynamic show-length variation
Methods for dynamic show-length variation are disclosed herein. Such methods can include: a track extending from a starting position to a termination position; a first simulation vehicle that can move along the track from the starting position to the termination position; and a content presentation feature. Such methods can further include a processor. The processor can: determine a departure of the simulation vehicle from the starting position; provide content having a beginning, an end, and a plurality of scenes to the content presentation feature while the simulation vehicle is en route between the starting position and the termination position; and customize the length of the provided content so the content reaches the end as the simulation vehicle reaches the termination position.
US10561951B2 Method and device for fantasy sport player recommendations
A method and device are for fantasy sport applications including receiving a plurality of ranking values associated with a sport player; assigning a corresponding weight value to each ranking value; determining a score value as a function of the ranking value and the corresponding weight value; determining a final ranking value as a function of the score values for the sport player; and generating a recommendation for the sport player as a function of the final ranking value.
US10561949B2 Systems and methods for ordered array processing
The present disclosure is directed to methods and systems for processing replacements to a target array according to an ordered list. A system may provide automatic and intuitive identification of selectable tokens by iteratively identifying all selectable tokens for processing or replacement in an array, and, for each selectable token, determining a unique vector or angle to the selectable token from a predetermined position. The selectable tokens may be placed in a list ordered by the vector or angle. A user interface may indicate a candidate selectable token and allow the user to either select the token for processing or replacement, or navigate through the ordered list to a different candidate selectable token. In one such implementation, the user may modify the vector or angle, and the user interface may highlight another candidate selectable token corresponding to the modified vector or angle.
US10561947B1 Online trivia game system
An online trivia game system is provided, and more particularly systems and methods of providing a trivia game system for end-users to construct trivia games using an online database of trivia questions and answers in order to host live on-site trivia games.
US10561945B2 Methods and systems for incentivizing team cooperation in multiplayer gaming environments
Computer-implemented methods and systems for simulating a multiplayer game environment to allow players of different skill levels to concurrently play the same level of a gaming session, to encourage and incentivize cooperative team behavior, to match players based on subjective variables, such as likeability and a general fun factor, and to tailor gaming content based on the social group itself.
US10561943B2 Digital imaging method and apparatus
An apparatus and method for electronically creating combined digital images of a person and incorporating them into a series of background images or film clips making it appear as if the user were actually a part of the original imaging sequence. The camera can move to take the images from different angles and in an alternative embodiment there are multiple cameras situated such that they sequentially capture and store a series of images to be incorporated into the product. An alternative housing apparatus is in a booth for automatically producing an imaging sequence of a self-portrait of the user integrated into a stored background or film clip, including a cash or credit card receiving device, a computer triggered by cash or credit received in the device, a movable digital camera or video camera to view the user, a video monitor for self-viewing, and the possibility of one located outside the booth for advertising or amusement purposes. A series of stored digital imaging movie clips for selective withdrawal by the user where the captured sequence of the user is automatically integrated into stock stored movie clips and can be either output in an e-mail message posted to a board with a link to user's choice of e-mail friends' addresses for retrieval or a direct link to friend's and family's e-mail addresses or an output device with hard copy of personalized sequence to CD ROM or Video or hard copy print of a still image.
US10561941B2 Video game processing program and video game processing system
The present invention allows a processing load for carrying out matching of a plurality of users who satisfy a predetermined condition with each other to be reduced. The user is arranged for every attribute to carry out the matching. The plurality of users thus matched is allowed to play content together. Users with different attributes may alternately stand in a line in which the users are arranged. Further, the users are arranged by inputting a play request for content. Only selection of a condition of the content may be sufficient for the play request.
US10561938B2 Server, method of controlling a server, and program
Provided are a server, a method of controlling a server, and a program that can increase the variations on methods for acquiring an item or the like and enhance interest in a game. Included are receiving, from a user, an item change request for changing first item data; displaying, to the user, a selection screen to display a plurality of options after receiving the item change request; and providing the user with second item data when a selected option on the selection screen is a correct answer.
US10561935B2 Thumbstick for user input device
A thumbstick for a user input device comprises a tiltable post operable to output a control signal based on its position, with the post comprising external threads and a post anchor feature. An adjustable tensioning mechanism is configured to modify a tilt tension of the post. A cap comprises a cylindrical stem that defines a cavity. A base is moveable with the post and comprises a first cylindrical portion extending into the cavity, and a second cylindrical portion comprising internal threads and a base anchor feature. The internal threads mate with the external threads of the post to fasten the post to the base, and the base anchor feature abuts the post anchor feature to prevent displacement of the base toward the proximal end of the post.
US10561927B2 Dual axle skateboard and truck with outboard secondary wheels and method
Improved skateboards and methods of obtaining or providing skateboards with improved trucks. Trucks have two axles or axes, two primary wheels, and two secondary wheels, and skateboards have eight wheels, four in front and four at the rear portion of the skateboard. The four primary wheels support most or all of the weight of the skateboard when the skateboard is on a flat surface, and the two secondary wheels support the weight of one portion of the skateboard (e.g., front or rear) when the primary wheels cross a crack (e.g., a sidewalk contraction joint). In various embodiments, the secondary wheels are located outboard of the primary wheels. Further, in a number of embodiments, the axis of rotation or axle of the primary wheels remains parallel to that of the secondary wheels, whether the skateboard is going straight or turning.
US10561922B2 Impact indication and data tracking devices, systems, and methods
Devices and methods are generally provided for indicating the location of a most recent strike on a face of a golf club. One exemplary embodiment of an impact indication device can include a patch that can be attached to the face of a golf club and can display the impact location of a most recent strike without displaying impact locations of previous strikes. The impact locations of previous strikes can be removed from the patch without the user having to do anything more than take another swing. In some embodiments, the device includes a yield-stress material that assist in displaying impact a most recent impact location without displaying previous impact locations. Other features that can allow patches to work in this fashion, as well as methods related to the same, are also provided. Further, disclosures pertaining to a mobile impact recorder are also provided.
US10561919B1 Mobile trainer sled with shifting section striking pad
A portable athletic trainer sled having a strike pad capable of movements in multiple planes for teaching and practicing footwork, striking points, head placement and directional maneuvering techniques for contact sports, minimizing risk of concussion. The sled is light in weight, adjustable, and easily assembled and disassembled.
US10561911B2 Golf club heads and methods to manufacture golf club heads
Examples of golf club heads and methods to manufacture golf club heads are generally described herein. In one example, a golf club head may include a body portion with a toe portion, a heel portion, a rear portion, a front portion with a strike face, a sole portion, and a top portion with a plurality of weight ports. The body portion may define a periphery of the golf club head. The golf club head may also include a plurality of weight portions with each weight portion disposed in one weight port of the plurality of weight ports. Other examples and examples may be described and claimed.
US10561908B2 Golf club head
A golf club head including a face portion having an improved restitution factor is provided. The golf club head has a hollow structure and includes a face portion, a crown portion, a sole portion, and a side portion. The crown portion includes a first region that spreads out forward of a boundary line that extends from a heel side to a toe side, and a second region that spreads out rearward of the boundary line and is thinner than the first region. The crown portion further includes a protruding portion formed at position that is in a vicinity of the boundary line, is on the second region, and is rearward of the boundary line via a gap.
US10561907B2 Racket frame
Provided is a racket frame on which design change can be easily performed by simple processing. The racket frame includes a head formed in a ring shape along a face. On the head, a gut groove in which a base portion for connecting grommets is to be inserted is formed in a radially outer region of the head so as to be recessed toward a radially inner side, and a deformation promotion groove is formed in the radially outer region of the head so as to be recessed toward the radially inner side.
US10561900B2 System and method for range of motion analysis and balance training while exercising
A system and method for range of motion analysis while exercising, including methods for constructing user movement profiles based on repeated and typical user movements during exercises as are typical for an adult of a user's age, weight, etc., and capable of warning a user of unhealthy, unsafe, or anomalous movement patterns during exercise, using a balance trainer, range of motion analyzer, and a plurality of sensors in conjunction with an exercise device, in an effort to reduce health risks to users during exercise with an enhanced or mixed reality exercise device.
US10561898B1 Gait assistive device
A system for gait training which includes a slidable assembly for attaching to the foot with or without a shoe, on the affected side of a subject. When the subject shifts his or her body weight away from the affected side, the slidable assembly is capable of forward and backward movement to follow the swinging movement of the leg. When the subject shifts their body weight to the affected side and thereby applies weight to his or her swinging leg and the slidable assembly, a passive braking system is automatically actuated arrests any further movement of the affected limb.
US10561896B2 Exercise machine with multiple platforms
An exercise machine with multiple platforms for an exerciser to perform a variety of exercises generally includes an elongated frame structure supporting stationary first and second end platforms, a longitudinal rail extending between the end platforms and having an upper surface comprising a central platform, and a slideable carriage platform that reciprocates on the rail over the central platform and between the end platforms. The platforms provide multiple support surfaces at multiple elevations on which exercisers can position parts of their bodies during exercise. The platforms may be provided with positioning indices and provide continuous support surfaces over substantially the entire length of the exercise machine. The central platform may be provided with finger grips for exercisers to grasp. One or more mounting platforms may be provided to facilitate mounting and dismounting of the exercise machine.
US10561894B2 Treadmill with removable supports
A treadmill includes a platform where the platform includes a first side panel and a second side panel spaced apart at a distance from the first side panel, and a gap defined between the first side panel and the second side panel. The treadmill also includes a running deck contained within the platform and exposed within the gap, a first pulley connected to the running deck, a second pulley connected to the running deck opposite the first pulley, a tread belt surrounding the first pulley and the second pulley, a first post removably connected to the platform, a second post removably connected to the platform, and a first rail transversely connected to the first post and the second post.
US10561888B2 Plank assist device
A plank assist device is presented comprising a base and a strap. The base has a first portion for supporting a human palm and a second portion for supporting a portion of a human thumb. The first portion comprises a first portion top surface, a first portion bottom surface, a first portion rear end and a first portion front end. The second portion comprises a second portion top surface, a second portion bottom surface, a second portion rear end and a second portion front end. The second portion is shorter in length and narrower in width than the first portion. In addition, the first portion rear end may be higher in height than the first portion front end, and the second portion rear end may be higher in height than the second portion front end.
US10561887B2 Vehicle seat assembly for physical exercise
A vehicle seat assembly includes a seat base, a seat back rotatably connected to the seat base, a seat bottom mounted on the seat base, and at least one of the following mounted to one of the seat base, seat back, and seat bottom: a resistance mechanism structured to exert a biasing force on at least one exercise arm operatively connected to the resistance mechanism; a bicycle seat receptacle structured for detachably mounting a bicycle seat to the seat base; and a docking mechanism structured for detachably mounting a pedal mechanism to the seat base.
US10561886B2 Sand training bag
Described is a sand training bag for sand training. It includes a set of bag walls which includes a training surface wall and a perimeter wall. The sand training bag is transitionable between a closed bag configuration in which the set of bag walls defines a bag chamber to an open pit configuration in which the set of bag walls forms a sand training pit with the training surface wall forming a floor of the sand training pit and the perimeter wall forming a perimeter side wall of the sand training pit, the sand training pit being provided to receive and hold a quantity of sand.
US10561885B1 Weighted exercise bag apparatus and methods of use
An exercise bag apparatus, comprising: a cover comprising a first re-sealable opening; an inner sleeve placed within the cover when the exercise bag apparatus is fully assembled, the inner sleeve comprising a second re-sealable opening and an inner cavity configured for holding a weighty substance therein; and at least one user interface disposed on the cover.
US10561874B2 Fluid control assemblies for sprinkler systems
Automatic fluid control assemblies and methods for fire protection include an arrangement of electrically operated control points, a valve body and a controller to operate the fluid control assembly. The automatic fluid control assembly has an inlet, an outlet and a valve body to control flow between the inlet and the outlet. An electric latch includes a first electrically operated control point and a second electrically operated control point in fluid communication with a control line to control the flow of fluid from the inlet to the valve body and outlet. The methods of fluid control include controlling a plurality of electrically operated control points to perform any one of: a leak test, a trip test, a flow test, a water delivery test, and a validation test of a non-trip condition and a trip condition.
US10561873B2 Angled bracket for a fire sprinkler support assembly
A fire sprinkler support assembly is provided. In some approaches, the fire sprinkler support assembly may include a bracket bar extending transverse to a beam, and a bracket assembly coupled to the bracket bar. The bracket assembly may include an upper wall and a set of plates extending from the upper wall, wherein the set of plates have a first end coupled to the bracket bar. An interior angle between the set of plates and the bracket bar is less than 90 degrees (e.g., 80-85°). The bracket assembly may further include a seating frame extending from a second end of the set of plates, the seating frame including a first member and a second member disposed on opposite sides of the beam. The fire sprinkler support assembly may further include a fastener extending through an opening of the upper wall to couple the set of plates to the bracket bar.
US10561870B2 Bracket interlock systems
A method of operating safety mechanism includes extending a safety pin to block a poppet from opening a flow path from a pressure vessel in the event of the pressure vessel being unmounted from a bracket or in the event of the bracket being unmounted from a support structure. The method includes retracting the safety pin to allow free movement of the poppet for opening the flow path only in the event of the pressure vessel being mounted to the bracket and the bracket being mounted to a support structure.
US10561864B2 Coupling device for a breathing apparatus
A coupling device for a breathing apparatus, characterized in that a connecting device is inseparably connected to the regulator hose, and can be coupled with at least two couplers, each having a flow check valve, for connection to a breathing gas source. Other aspects are described and claimed.
US10561861B2 Videographic display of real-time medical treatment
Systems and methods for creation of a videographic representation of a real-time medical treatment by a processor operating in conjunction with a treatment device and an imaging device are described. The representation may include real-time imaging data, a representation of real-time treatment data and contours of relevant anatomy among other things. Related systems and techniques are also described.
US10561858B2 Method and apparatus pertaining to radiation-treatment plan optimization
A radiation-treatment plan that comprises a plurality of dose-delivery fractions can be optimized by using fraction dose objectives and at least one other, different dose objective. This use of fraction dose objectives can comprise accumulating doses delivered in previous dose-delivery fractions. The other, different dose objective can comprise a remaining total dose objective, a predictive dose objective, or some other dose objective of choice. An existing radiation-treatment plan having a corresponding resultant quality and that is defined, at least in part, by at least one delivery parameter can be re-optimized by specifying at least one constraint as regards that delivery parameter as a function, at least in part, of that resultant quality and then applying that constraint when re-optimizing the existing radiation-treatment plan.
US10561851B2 Interconnection of conductor to feedthrough
A method of interconnecting a conductor and a hermetic feedthrough of an implantable medical device includes welding a lead to a pad on a feedthrough. The feedthrough includes a ceramic insulator and a via hermetically bonded to the insulator. The via includes platinum. The pad is bonded to the insulator and electrically connected to the via, includes platinum, and has a thickness of at least 50 μm. The lead includes at least one of niobium, platinum, titanium, tantalum, palladium, gold, nickel, tungsten, and oxides and alloys thereof.
US10561849B2 Facilitating integrity of telemetry connectivity between an implantable device and a remote device
Systems, apparatus, methods and computer-readable storage media that facilitate monitoring the integrity of telemetry connectivity between an implantable device and an external device are provided. In one embodiment, an implantable device includes a monitoring component that monitors advertisement signal information identifying an amount of advertisement signals transmitted to the external device within a defined time period, and telemetry session information identifying an amount of the telemetry sessions that are established between the external device and the implantable device within the defined time period. A connectivity assessment component of the implantable device further determines whether a telemetry connectivity problem exists between the external device and the implantable device based on a degree of miscorrelation between the advertisement signal information and the telemetry session information.
US10561846B2 Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
A method of inhibiting the release of a proinflammatory cytokine in a cell is disclosed. The method comprises treating the cell with a cholinergic agonist. The method is useful in patients at risk for, or suffering from, a condition mediated by an inflammatory cytokine cascade, for example endotoxic shock. The cholinergic agonist treatment can be effected by stimulation of an efferent vagus nerve fiber, or the entire vagus nerve.
US10561845B2 Therapy adjustment based on patient event indication
An indication that a patient event occurred may be used to evaluate the efficacy of at least one therapy program and/or adjust therapy delivery to the patient. In some examples, the patient event indication includes patient input that may be received via an event indication button of a programming device. In some examples, therapy delivery may be adjusted by adjusting at least one therapy parameter value, switching therapy programs or therapy program groups or restarting a therapy cycle of a medical device.
US10561844B2 Diaphragm pacing systems and methods of use
Diaphragm pacing systems and methods are disclosed for providing respiratory therapy to a patient. The diaphragm pacing systems can provide rapid insertion and deployment of pacing electrodes in critically ill patients who require intubation and invasive Positive Pressure Mechanical Ventilation (PPMV) in order to support the physiological requirements of the human ventilatory system. The systems and methods make best use of the contractile properties of the diaphragm muscle and prevent muscle disuse and muscle atrophy. This can be carried out by engaging the phrenic nerves using patterned functional electrical stimulation. The diaphragm pacing systems can be designed to seamlessly interface with any commercially available positive-pressure ventilatory assistance/support equipment such as is commonly in use in hospital intensive care units (ICU) for treating critically ill patients with breathing insufficiencies, pain, trauma, sepsis or neurological diseases or deficits.
US10561843B2 Transvascular nerve stimulation apparatus and methods
Electrode structures for transvascular nerve stimulation combine electrodes with an electrically-insulating backing layer. The backing layer increases the electrical impedance of electrical paths through blood in a lumen of a blood vessel and consequently increases the flow of electrical current through surrounding tissues. The electrode structures may be applied to stimulate nerves such as the phrenic, vagus, trigeminal, obturator or other nerves.
US10561842B2 Layered midfield transmitter with dielectric tuning
Systems, devices, and methods are discussed herein for wirelessly transmitting power and/or data to an implanted device, such as an implanted electrostimulator device. In an example, the subject matter includes a layered transmitter device with multiple conductive planes and excitation features. The transmitter device can be tuned to identify and apply device parameters for efficient wireless communication with a deeply implanted device. The transmitter is generally configured for midfield powering applications by providing signals that give rise to propagating signals inside of body tissue.
US10561841B2 Retina prosthesis
The invention provides a retinal prosthetic method and device that mimics the responses of the retina to a broad range of stimuli, including natural stimuli. Ganglion cell firing patterns are generated in response to a stimulus using a set of encoders, interfaces, and transducers, where each transducer targets a single cell or a small number of cells. The conversion occurs on the same time scale as that carried out by the normal retina. In addition, aspects of the invention may be used with robotic or other mechanical devices, where processing of visual information is required. The encoders may be adjusted over time with aging or the progression of a disease.
US10561840B2 Method and device for enhancing memory consolidation
The present invention relates to methods and devices to consolidate memory and/or cognitive functions by monitoring brain rhythms and delivering a stimulus at an appropriate stage of sleep cycle.
US10561839B2 Systems for peripheral nerve stimulation
A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator can have electrodes that are placed circumferentially around the patient's wrist or arm. Specific nerves in the wrist or arm can be targeted by appropriate spacing of the electrodes. Positioning the electrodes on generally opposing sides of the target nerve can result in improved stimulation of the nerve. The stimulation pattern may alternate between the nerves. Improved stimulation algorithms can incorporate tremor feedback, external data, predictive adaptation, and long-term monitoring data.
US10561835B2 Implantable medical lead with threaded fixation
The disclosure is directed to securing electrodes of a medical lead adjacent to a target tissue site. The medical lead may include one or more threaded fixation structures disposed circumferentially about the outer surface of the lead body, or elongated member, that resembles a “screw” or “auger.” During implantation, a clinician may rotate the entire lead to “screw” the lead into the tissue of the patient until electrodes of the lead reside adjacent to a target tissue. In this manner, the threaded fixation structure secures the lead within the patient to resist lead migration and improper therapy and provide a fine adjustment for depth of placement. The threaded fixation structure may be disposed on a portion of the lead proximal to or distal to the electrodes of the lead or over the portion of the lead that includes the electrodes.
US10561834B2 Apparatus for electrically mediated delivery of therapeutic agents
Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes. The apparatus will also comprise means for generating an electrical field which facilitates the intracellular delivery of a therapeutic agent, which means is operatively connected to said electrodes at least in their deployed state.
US10561831B2 Transdermal administration device packaged body
A transdermal administration device packaged body includes a transdermal administration device including an administration member housed in a container, the administration member having at least one projection protruding from a first surface of a substrate, and an outer package which houses the transdermal administration device and has a bag form including a front component and a rear component. The front component is positioned on a first surface side of the substrate, the rear component is positioned on a second surface side opposite to the first surface side of the substrate, and the front component has an opening member configured to be pulled open to open the outer package.
US10561830B2 Cell impregnated sleeve for paracrine and other factor production
Certain embodiments according to the present invention provide sleeve devices suitable for a wide range of therapeutic uses. In accordance with certain embodiments, the therapeutic sleeve device includes a nanofiber fabric assembly, which defines a plurality of pores, and at least one layer of cells embedded in the nanofiber fabric assembly.
US10561829B2 Method and articles for treating the sinus system
A method of treating a sinus cavity of a subject includes advancing a distal portion of a light source through a drainage pathway of a sinus cavity and into the sinus cavity and visually observing a transdermal light emitted from the light source. A distal portion of a substantially rigid inner guide member of a balloon dilation catheter is advanced into the drainage pathway, the balloon dilation catheter including a movable shaft including a balloon that is slidably mounted on the substantially rigid inner guide member. The movable shaft and balloon are advanced distally over the substantially rigid inner guide member to place a portion of the balloon in the drainage pathway whereby the balloon is inflated.
US10561827B2 Disrupting fibrin sheath from a host blood vessel and visualization thereof
A percutaneous transluminal angioplasty (PTA) catheter may be configured to perform vein expansion and occlusion. A infusion port (132) located proximal to the occlusion feature (162) can be used to inject contract enhancement agent as well as other substances. The catheter can be used especially advantageously in vascular regions associated with hemodialysis access.
US10561818B2 Pre-curved steerable catheter with pull-wires for dexterous deflection control
A pre-curved steerable catheter includes a catheter body (102) having a distal end portion. The distal end portion includes a permanently curved flexible end portion (110). A pull wire (108) is disposed in a pull wire lumen within the catheter body. The pull wire extends from the distal end portion to a proximal end portion of the catheter body wherein the pull wire, when tensioned, provides a change in an angle of the curved flexible end portion of the catheter body.
US10561809B2 Breath actuated dry powder inhaler
A breath actuated dry powder inhaler with a single air circulation chamber for de-agglomeration of entrained powdered medicament using the energy of the inspiratory air stream. The chamber has a substantially polygonal sidewall, a plurality of air supply channels entering the chamber substantially tangentially to its sidewall. A powder channel extends through a powder dose supply region of the inhaler tangentially into the chamber. An air outlet axially extends from a discharge and connects to a discharge channel that extends to a mouthpiece. The polygonal sidewall comprises at least six straight line segments, each straight line segments being spaced at the same first distance from an adjacent one forming the plurality of air supply channels. The air supply channels have the same width. The powder channel is defined by two straight line segments which are spaced from each other at a second distance which is larger than the first distance.
US10561808B2 Dose counter for inhaler having an anti-reverse rotation actuator
A dose counter for an inhaler includes a counter display arranged to indicate dosage information, and a drive system arranged to move the counter display incrementally in a first direction from a first station to a second station in response to actuation input. A regulator is provided which is arranged to act upon the counter display at the first station to regulate motion of the counter display at the first station to incremental movements.
US10561806B2 Mouthpiece cover for an inhaler
A mouthpiece cover for an inhaler is described. The mouthpiece cover is designed for use with a dry powder inhaler and is provided with structural features to prevent a patient from inhaling the cover.
US10561803B2 Ultrasonic atomizer and electronic cigarette
The present invention discloses an ultrasonic atomizer and electronic cigarette. The ultrasonic atomizer includes an atomization piece and a liquid guide structure, which guides liquid onto an upper surface of the atomization piece; the liquid guide structure communicates with a liquid storage cavity; the upper surface of the atomization piece communicates with an airflow passage; and the atomization piece comprises a piezoelectric ceramic layer and an electric conductor, which drives vibration of the piezoelectric ceramic layer. No micropore needs to be provided in the atomization piece of the present invention to eject the atomized gas, thereby being free of the situation that the micropore is blocked by larger atomized gas particles, resulting in that the atomized gas cannot be ejected, and meanwhile the situation of liquid leakage of the atomizer can be better prevented.
US10561795B2 Convertible plungers, film coated plungers and related syringe assemblies
A convertible plunger is provided comprising an internal portion and a generally cylindrical exterior surface. At least a portion of the exterior surface is maintained in an initial expanded state by a property of the internal portion. The expanded state is reducible to a constricted state by an operation that is applied to the internal portion of the plunger to alter the property. A film coating may also be applied to a sidewall of the sleeve to reduce a sliding friction between the sleeve and barrel. A film coating may also be applied to a nose cone of the plunger to provide a barrier between the plunger and product in the barrel.
US10561787B2 Syringe pump and related method
A syringe pump includes a lead screw, a motor, and a sliding block assembly. The lead screw has threads and the motor is coupled to the lead screw to rotate it. The half-nut housing has a half nut and a barrel cam. The half nut is disposed within the half-nut housing. The half nut has half-nut threads at an end adjacent to the lead screw void. The half nut engages or disengages with the threads of the lead screw. The half nut includes a half-nut cam-follower surface and a half nut slot. The barrel cam is disposed within the half-nut housing and engages with the half-nut cam-follower surface. The barrel cam includes a pin to fit within the half nut slot such that the barrel cam rotates between a first position and a second position to actuate the half nut between the engagement position and the disengagement position, respectively.
US10561786B2 Port-flushing control valve
A valve is disclosed that has a body with an inlet, an outlet, and a needleless access port coupled to the body. The access port has an interior space and is configured to be actuated by a needleless connector. The inlet is selectively coupled to the outlet through the interior space such that fluid entering the inlet entirely flows through the interior space to the outlet.
US10561785B2 Method and/or system for closed-loop control of glucose to a treatment range
Subject matter disclosed herein relates to monitoring and/or controlling blood glucose levels in patients. In particular, one or more substances may be delivered to a patient at a particular infusion rate while the patient's estimated glucose level is within a predetermined range. A different insulin infusion rate may then be applied if the patient's estimated blood glucose level deviates outside of the predetermined range.
US10561781B2 Blood filtering device
A blood filtering device has a filtration section with filter medium separating raw side and clean side. A first communication path connects raw side and a first variable blood reservoir volume; a second communication path connects raw side and a second variable blood reservoir volume coupled to a receptacle. When varying the first variable blood reservoir volume, blood contained therein flows through first communication path to raw side, plasma/serum passes through the filter medium from raw side to clean side, and residual blood flows from raw side through second communication path into the second variable blood reservoir volume. When varying the second variable blood reservoir volume, blood contained therein flows through second communication path to raw side, plasma/serum passes through the filter medium from raw side to clean side, and residual blood flows from raw side through first communication path into first variable blood reservoir volume.
US10561780B2 Dialysis system having inventory management including online dextrose mixing
An automated peritoneal dialysis system and machine configured to perform dextrose mixing are disclosed. An example dialysis machine includes at least one pump, a first dialysate having a first dextrose level placed in fluid communication with the at least one pump, and a second dialysate having a second dextrose level placed in fluid communication with the at least one pump. The example dialysis machine also includes first and second valves placed between the first and second dialysates and the at least one pump. The example dialysis machine further includes a logic implementer programmed to operate the at least one pump and the first and second valves to mix the first and second dialysates so as to form a third dextrose level.
US10561778B2 Split reservoir bags and method of using split reservoir bags to improve the heating and generation of dialysate
The present specification provides a reservoir bag for containing a dialysate during a dialysis treatment. The bag has four walls and a membrane extending from a first wall to a second opposing wall which divides the bag into a first and a second sub-reservoir having changeable volumes. The maximum volume of each sub-reservoir is between 80 to 100% of the entire volume of the bag. The bag further includes at least an inlet and an outlet positioned in at least one of the walls for enabling fluid entry into and exit out of the first sub-reservoir and at least an inlet and an outlet positioned in at least one of the walls for enabling fluid entry into and exit out of the second sub-reservoir.
US10561776B2 Fluid circuit for delivery of renal replacement therapies
A portable dialysis cabinet for use in dialysis. The portable dialysis cabinet can have a size and weight that facilitates easy movement of the cabinet from one location to another with relative ease. The portable dialysis cabinet can have additional features necessary to facilitate portability, such as wheels and a handle. In general, the portable dialysis cabinet can contain all the necessary components for performing a dialysis session.
US10561770B2 Breast pump assembly
Systems and methods for pumping milk from a breast, wherein the milk is expressed from the breast under suction and milk is expulsed from the pumping mechanism to a collection container under positive pressure. In one approach, the breast pump assembly includes a breast adapter and a receptacle configured to cup the breast adapter, and the breast adapter is removable from the receptacle.
US10561768B2 Reduced-pressure wound treatment systems and methods employing microstrain-inducing manifolds
Microstrain-inducing manifolds, systems, and methods are presented that involve microstrain-inducing manifolds that include a plurality of shaped projections for creating microstrain. The shaped projections may be tapered projections. A system may include a sealing member for placing over the tissue site, a microstrain-inducing manifold, and a reduced-pressure subsystem that delivers reduced pressure to the sealing member. The reduced pressure causes the shaped projections to create microstrain at the tissue site. Other methods, apparatuses, and systems are also presented.
US10561767B2 Medical suction device
Systems and methods for a cartridge which may be included in a medical suction device are disclosed herein. In one embodiment, a cartridge may comprise a porous filler material loaded with absorption granules for absorbing liquids, and a hydrophobic liquid barrier which is permeable only to one or more of air and gasses, and positioned within the cartridge so that liquids in the cartridge cannot exit the cartridge. The cartridge may further comprise perforated walls and sealed walls, arranged within the cartridge in an alternating order and orientated parallel to one another and perpendicular to a net flow direction of fluids in the cartridge, and spaced from one another such that passages are formed between the walls.
US10561760B2 Space modulation apparatus
A space modification apparatus includes a treatment tank configured to generate a gas phase around a rotating center of a rotating flow of a liquid by rotating the liquid, a first electrode of which at least a part is in the treatment tank so as to be in contact with the liquid in the treatment tank, a second electrode in contact with the liquid in the treatment tank, and a power source configured to apply a voltage between the first electrode and the second electrode to generate plasma in the gas phase to generate modification components, the modification components being dissolved and dispersed in the liquid, and a modification liquid being generated and retained in a storage tank. The modification liquid is sprayed or scattered from a nozzle into a treatment target space via a supply pump in the form of mist.
US10561755B2 Volatile composition dispenser with retractable push button
There is a volatile composition dispenser comprising: a housing comprising a rear frame having a frame opening a push button movably disposed within the frame opening; and a cartridge aligned with the push button, the cartridge comprising a container having an orifice and containing a volatile composition, a rupturable substrate sealably attached to and covering the orifice, and rupture elements adjacent the rupturable substrate; and a resilient member aligned with the push button and the rupture elements wherein upon receiving a pressure on the push button, said resilient member moves the rupture elements into a first position in which the rupture elements engage with the rupturable substrate and wherein upon removing the pressure from the push button, said resilient member exerts a force on the push button and moves the rupture elements into a second position in which the rupture elements are not engaged with the rupturable substrate.
US10561754B2 Volatile composition dispenser with lockable button
There is a volatile composition dispenser comprising a housing comprising a rear frame having a frame opening, and an inner wall. A push button is movably disposed in the frame opening and the inner wall and is configured to be movable with respect to the inner wall from a first position to a second position wherein the push button is interlocked with the inner wall in the second position.
US10561753B2 Method of sterilizing medical devices, analyzing biological indicators, and linking medical device sterilization equipment
A biological indicator analyzer includes a plurality of wells, a plurality of organism detector features, and a user input feature such as a touch screen. Each well is configured to receive a respective biological indicator. Each organism detector feature is configured to detect whether a biological indicator disposed in a corresponding well of the plurality of wells contains a living organism. The touch screen is configured to receive user input and provide information to the user indicating a status of biological indicator analysis. The biological indicator analyzer may be used to analyze a biological indicator that was positioned in a sterilization chamber of a sterilizing cabinet along with at least one medical device that is to be sterilized. The analysis may indicate whether the sterilization cycle in the sterilization chamber as successful.
US10561748B2 Anthranilic acid derivatives
The present invention is directed to a novel compound of Formula 1 wherein the radiolabeled compound of Formula 1 is capable of being used as a radiotracer in PET imaging of a targeted localized tissue and targeted radionuclide therapy of one or more conditions that may be regulated or normalized via inhibition of transporter such as Pgp, BCRP or MRP I. The novel compounds of Formula 1 can also be used as substrates for binding with one or more ABC transporters. In particular, the present invention aids in diagnosis and therapeutic treatment of MDR disorders in all forms of cancers and neurological disorders of the central nervous system. The present invention further provides methods of preparation of compounds of Formula 1 and novel intermediates used in the preparation of compounds of Formula 1.
US10561747B1 Multifunctional cancer targeting nanoparticles
Multifunctional cancer targeting nanoparticles include a magnetic central core including gold coated iron oxide, an outer layer including trimethyl chitosan microspheres and folic acid and a linker between the central core and the outer layer, the linker including cysteamine. An anti-cancer drug can be supported by the outer layer. The multifunctional cancer targeting nanoparticle can provide simultaneous cancer cell diagnosis and therapy. An amount of heat and an amount of the anti-cancer drug released by the nanoparticle can be controlled by application of a magnetic field.
US10561745B2 Stimuli-responsive magneto-plasmonic nanocarrier
Materials and methods for synthesizing magnetic core/gold shell nanoparticles and magneto-plasmonic nanostars are provided. Formulations comprising nanoparticles optionally bound to or co-loaded with a therapeutic agent encapsulated within liposomes are provided. A method for treating diseases (e.g., brain diseases) in a subject by administering to the subject a formulation comprising the nanoparticle formulation is also provided. Further, a method is provided for imaging a target site of a subject following the administering of the nanoparticle formulations.
US10561744B2 Multi-encapsulated formulations made with oxidized cellulose
A microsphere and method for forming the same are disclosed. The microsphere includes modified cellulose and at least one of a visualization agent, a magnetic material, or a radioactive material.
US10561739B2 Targeted pyrrolobenzodiazapine conjugates
Provided are Conjugate comprising PBDs conjugated to a targeting agent and methods of using such PBDs.
US10561737B2 Bispecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles
Herein is reported a bispecific antibody comprising a first binding specificity that specifically binds to a haptenylated payload and a second binding specificity that specifically binds to a blood brain barrier receptor.
US10561735B2 Solid formulations of liquid biologically active agents
The instant invention relates to a solid product comprising a liquid biologically active agent which is intimately associated to a stabilizing agent; particularly a solid product that can be reconstituted to a clear, stable, stabilized nanodispersion or loaded micelles comprising a polymer as a stabilizing agent and a liquid, preferably water immiscible, biologically active agent. The instant invention is further directed toward a process for the production of the above solid product; particularly to micelles or nanodispersions produced by hydration of a cake or powder of the solid product, produced via an effective treatment of a stabilized solution comprising for example a polymer as a stabilizing agent, such as an amphiphilic block copolymer or a small molecular weight surfactant, loaded with a liquid biologically active agent, such as propofol, an optional additive, and a suitable solvent.
US10561733B2 Process for producing nanoparticles laden with active ingredient
The present invention relates to a novel process for the production of nanoparticles laden with active compounds and to the use thereof as medicaments. The process for the production of nanoparticles comprises the steps (a) dissolution of at least one active compound and at least one polymer in an organic solvent, (b) mixing of the solution prepared in step (a) with an aqueous phase, (c) evaporation of the organic solvent, (d) purification of the nanoparticles laden with active compound obtained in step (c) by means of dialysis against aqueous dialysis solution comprising the same active compound.
US10561726B2 Methods of treating cancer using compositions of antibodies and carrier proteins with antibody pretreatment
Described herein are methods, formulations and kits for treating a patient with cancer with anti-VEGF antibodies and albumin-bound chemotherapeutic/anti-VEGF antibody nanoparticle complexes.
US10561725B2 Method of inducing the production of protective anti-HIV-1 antibodies
The present invention relates, in general, to an immunogen for HIV vaccination and, in particular, to a method of inducing the production of protective anti-HIV antibodies by targeting B cell germline and clone intermediates using a combination of HIV envelope and non-HIV immunogens. The invention also relates to compositions suitable for use in such a method.
US10561723B2 Treatment and prevention of anal conditions
The invention relates to methods, compositions, and kits for treating a condition with an immune response modifier and a human papillomavirus (HPV) vaccine. Conditions treatable with the methods, kits and compositions include but are not limited to neoplasia, anal intraepithelial neoplasia, high-grade squamous intraepithelial neoplasia, dysplasia, anal dysplasia, dysplastic lesion, high-grade dysplastic lesion, condyloma, anal cancer, anal tumor, HPV infection, and any HPV-induced condition.
US10561720B2 Pharmaceutical compositions, comprising a combination of select carriers, vitamins, tannins and flavonoids as antigen-specific immuno-modulators
The present invention provides adjuvant compositions that are capable of modulating the immune response in a subject, including enhancing or suppressing the immune response. These adjuvant compositions may also be used to enhance or suppress the immunogenicity of antigens by enhancing or suppressing antigen-presentation activity, enhancing or suppressing innate immune responses through activation or suppression of, e.g., natural killer cells, and/or direct activation of subsets of B and/or T cells. Also provided are methods of making the adjuvant compositions as well as methods of using the adjuvant compositions. In certain embodiments, the compositions comprise combinations of the following: a pharmaceutically acceptable carrier, a flavonoid, a tannin and a vitamin. The compositions may further comprise an antigen.
US10561711B2 Rapid action insulin formulations and pharmaceutical delivery systems
The present invention provides rapid-acting insulin and insulin analogue formulations. The invention further provides delivery devices, particularly infusion sets, which allow for the rapid absorption of insulin and insulin analogues, as well as other active agents. Methods of using the insulin and insulin analogue formulations as well as the insulin delivery devices for treating subjects with diabetes mellitus are also provided.
US10561710B2 Goblet cell replacement therapy
Described herein is the finding that activators of CXCR3, such as proteins that bind CXCR3 (e.g., IP-9, IP-10 and PF4), enhance the density of goblet cells in the eye. Goblet cells in the conjunctiva are the primary source of tear mucus. Accordingly, the present disclosure describes methods of treating dry eye syndrome by administering an activator of CXCR3. Also described are methods of increasing goblet cells density, such as goblet cell density in the conjunctiva.
US10561703B2 Method of modulating sex hormone levels using a sex hormone secretion modulator
Provided are a hormone secretion modulator including a peptide derived from telomerase, more particularly, a peptide including an amino acid sequence of SEQ ID NO: 1, an amino acid sequence having a sequence identity of at least 80% with SEQ ID NO: 1, or a fragment thereof, a pharmaceutical composition including the hormone secretion modulator, and a use of the pharmaceutical composition for treatment, alleviation, or prevention of diseases caused by excessive or deficient levels hormones.
US10561700B2 Use of overground part of Hedychium coronarium Koenig in reducing blood glucose; extracts and compositions of overground part of Hedychium coronarium Koenig and their uses
The present invention is related to the use of an overground part of Hedychium coronarium Koenig in lowering blood glucose, increasing insulin levels and treating and/or preventing diabetes without overly reducing blood glucose in a subject; i.e., not reducing blood glucose in a fasting subject. The present invention also relates to an extract and composition of the overground part of Hedychium coronarium Koenig and its use in lowering blood glucose, increasing insulin levels and treating and/or preventing diabetes.
US10561698B2 Hand sanitizer composition and method of manufacture
A hand sanitizing composition and a method of manufacture, wherein the composition includes a solvent from about 78% to about 96% by weight sufficient to operate as a carrier and solvent. The composition includes tetrasodium EDTA and/or Sodium Citrate from about 0.01% to about 1% by weight to operate as a buffer, stabilizer and chelating agent. The composition includes a humectant selected from the group of humectants consisting of: Cetyl Alcohol, Ceteryl Alcohol, and Steryl Alchohol from about 1.5% to about 5.5% by weight to emulsify, thicken and lubricate. The composition includes an emollient from about 0.1% to about 3.2% by weight and an antioxidant vitamin from about 0.01% to about 1% by weight. The composition includes a soothing agent in a therapeutically significant amount and a conditioner.
US10561695B2 Composition having functions of improving kidney yang, enhancing immunity and relieving fatigue, method for producing the same and use thereof
The present disclosure relates to the field of healthcare foods. Disclosed is a composition having functions of improving kidney yang, enhancing immunity and relieving fatigue, which is an aqueous extract of Astragalie radix, Rehmanniae radix, Eucommiae cortex, Morindae officinalis radix, Lycii fructus and Polygonati rhizoma. By using six traditional Chinese herb medicines, Astragalie radix, Rehmanniae radix, Eucommiae cortex, Morindae officinalis radix, Lycii fructus and Polygonati rhizoma for decoction extraction, a composition having functions of improving kidney yang, enhancing immunity and relieving fatigue is obtained. Through synergetic function of each traditional Chinese herb medicine, the composition achieves a better effect comparing with similar products. In addition, the species of traditional Chinese medicine in the composition is relatively fewer, lowering the potential safety hazard, and the method is simple and the cost is low.
US10561692B2 Allergy-inhibiting sea grape extract, its preparation method and application thereof
Present invention relates to an allergy-inhibiting sea grape extract, its preparation method and thereof. The preparation method includes following steps: the sea grape is blended in distilled water in the weight ratio of 1:1˜20, mix thoroughly, stir at 20˜100° C. for 30˜120 minutes. The fluid obtained after the first filtration is the sea grape extract. The sea grape extract can be subjected to the second filtration by using EW, PW and DK membranes and freeze-dried to give a refined sea grape extract. The invention exhibits superior allergy-inhibiting effect; moreover, the prepared extract does not cause allergy and can be used in cosmetics and food.
US10561688B2 Method for preparing of endothelial cells by transformation (transdifferentiation) of adult fibroblast, and use thereof
The present invention relates to a method of preparing vascular endothelial cells by transforming (transdifferentiating) adult fibroblasts and a composition, which includes vascular endothelial cells prepared according to the method, for preventing and treating ischemic diseases, the method including a step of transducing adult fibroblasts with a gene. In particular, the present invention confirms that five factors, Foxo1, Er71, Klf2, Tal1, and Lmo2, induce transdifferentiation of adult fibroblasts into induced vascular endothelial cells. Furthermore, the present invention confirms that three factors, Er71, Klf2, and Tal1 induce transdifferentiation of human adult fibroblasts into induced vascular endothelial cells. The resultant induced endothelial cells enable lower limb salvaging by angiogenesis in lower limb ischemic animal models, showing that the induced endothelial cells can be effectively used for prevention or treatment of ischemic diseases.
US10561684B2 Pharmaceutical composition for preventing or treating sensorineural hearing loss or tinnitus including platelet-rich plasma and method using the same
Provided are a pharmaceutical composition for preventing or treating sensorineural hearing loss or tinnitus including platelet-rich plasma, and a method of preventing or treating sensorineural hearing loss or tinnitus using the same.
US10561680B2 Topical composition for the treatment of mucosal lesions
Topical composition for the treatment of mucosal lesions It relates to a topical composition comprising specific amounts of: a) a hyaluronic acid or a pharmaceutically or veterinary acceptable salt thereof, b) one or more adhesive agents, and c) a non-absorbable antibiotic; to delivery devices comprising it; and to its uses in medicine, in particular, in the treatment and/or prevention of mucosal lesions; in the prevention of postpolypectomy syndrome; as adjuvant therapy to mechanical treatments in gastrointestinal perforations, and as sealant treatment in surgical anastomoses and leaks or fistulas in gastrointestinal tract.
US10561677B2 Anti-bacterial applications of poly-N-acetylglucosamine nanofibers
Described herein are compositions comprising shortened fibers of poly-N-acetylglucosamine and/or a derivative thereof (“sNAG nanofibers”) and anti-bacterial applications of such compositions. The sNAG nanofibers may be formulated into compositions for the prevention and/or treatment of bacterial infections and diseases associated with such infections. Regimens employing such compositions are also described.
US10561674B2 Processes for the preparation of phospholipid-enriched dairy products as neutraceuticals for the formulation of functional foods
The present invention discloses processes for the preparation of phospholipid-enriched dairy products as nutraceuticals for the formulation of functional foods, the processes include the steps of: combining a non-dairy-based PL-containing material, having phosphatidylserine (PS) and/or phosphatidic acid (PA) in the PL-containing material, wherein the PS and/or PA is derived in part from an enzymatically-processed lecithin as a PS-calcium and/or -magnesium salt and/or a PA-calcium and/or-magnesium salt via transphosphatidylation with phospholipase D in the presence of L-serine and a calcium and/or magnesium salt, with water and an oil component to form a paste; removing an excess amount of the water from the paste to form a PL-oil solution; and mixing the PL-oil solution with a dairy component, thereby obtaining a PL-enriched dairy product. Alternatively, the PL-oil solution has a weight-to-weight (w-w) concentration of at least about 0.01% of a residual amount of the water to the PL-containing material.
US10561669B2 Oral quetiapine suspension formulations with extended shelf life and enhanced bioavailability
A quetiapine fumarate composition for oral administration is provided comprising a pharmaceutically acceptable salt or solvate of quetiapine existing as a suspension in an aqueous carrier agent. The inventive liquid formulation demonstrates high bioavailability consistent with approved dosage forms, low agglomeration, reduced content of excipients commonly used in solid oral dosage forms and extended shelf life stability. Also provided is a method of manufacturing a liquid quetiapine suspension composition for oral administration and methods of administering therapeutically effective dosages of an oral liquid quetiapine suspension composition to patients in need thereof.
US10561666B2 Amido compounds as RORγt modulators and uses thereof
Amido compounds are disclosed that have a formula represented by the following: and wherein n1, n2, R1a, R1b, R2, R3, R4, R5, and R6 are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.
US10561662B2 4-oxo-3,4-dihydro-1,2,3-benzotriazine modulators of GPR139
The present invention provides a method for treating a disease, disorder or condition associated with GPR139 using compounds of formula 1: which are agonists of GPR139, certain compounds encompassed by formula 1, pharmaceutical compositions thereof, processes for making the compounds, and intermediates thereof.
US10561658B2 Thieno- and pyrrolopyrimidine analogues as anticancer agents and methods of use thereof
The present invention provides for the design and synthesis of halogenated thieno- and pyrrolopyrimidine compounds that exhibit cancer proliferation inhibitory activity and the use thereof for cancer treatment.
US10561656B2 Organic compounds
The present invention relates to PDEI inhibitory compounds of Formula I as described herein, processes for their production, their use as pharmaceuticals and pharmaceutical compositions comprising them.
US10561649B2 Pharmaceutical combination of opioid and prostaglandin compound
Provided is a method for treating a condition or disease which is one of the indications for opioid use, which comprises administering a combination of: (a) a pharmaceutically effective amount of an opioid, and (b) a pharmaceutically effective amount of a prostaglandin (PG) compound represented by the formula (I): to a patient in need thereof.