Document Document Title
US10544683B2 Air-film cooled component for a gas turbine engine
A component for a gas turbine engine that separates a cooling air plenum from a heated gas environment. The component defines a hot section surface adjacent to the heated gas environment having a plurality of cooling apertures fluidically connecting the cooling air plenum to the heated gas environment to allow a cooling air to flow from the cooling air plenum to the heated gas environment through the plurality of cooling apertures. The plurality of cooling apertures each have an aperture diameter of less than about 3 millimeters (mm) and an average surface roughness of less than about 1 micrometer (1 μm).
US10544680B2 Last turbine rotor disk for a gas turbine, rotor for a gas turbine comprising such last turbine rotor disk and gas turbine comprising such rotor
A gas turbine having a compressor section provided with a plurality of compressor blades and vanes for compressing air; a combustion section; a turbine section a rotor having an axis and extending from a compressor section to the turbine section for supporting the compressor and turbine blades, the rotor having a last rotor disk having a downstream portion for supporting a bearing cover and an upstream portion for supporting a last turbine blade; and a cooling duct system configured for supplying cooling air from a downstream end of the turbine section to the last turbine blade passing inside the last rotor disk, and having an axial bore in the downstream portion of the last rotor disk along the rotor axis; and a first plurality of inclined radial bores in the upstream portion of the last rotor disk off the axis.
US10544676B2 Situ gas turbine prevention of crack growth progression
A method for remotely stopping a crack in a component of a gas turbine engine is provided. The method can include inserting an integrated repair interface attached to a cable delivery system within a gas turbine engine; positioning the tip adjacent to a defect defined on a surface on the component; and locally heating the base of the defect. A method is also provided for clamping a crack defined between a first surface and a second surface of a component of a gas turbine engine. The method can include attaching a strap over the crack such that a first end of the strap is attached to the first surface of the component and the second end of the strap is attached to the second surface of the component.
US10544674B2 Multiphase flow meter with tuning fork
A flow meter includes a cylindrical tubing configured to be positioned in a wellbore, the cylindrical tubing including a flow mixer configured to produce a turbulent fluid flow of a multiphase fluid in the wellbore. The flow meter includes a tuning fork disposed in the cylindrical tubing separate from the flow mixer, the tuning fork configured to contact the turbulent fluid flow of the multiphase fluid and vibrate at a vibration frequency in response to contact with the turbulent fluid flow, and a controller to determine a fluid density measurement of the multiphase fluid based at least in part on the vibration frequency of the tuning fork.
US10544672B2 High-efficiency downhole wireless communication
A communication system for use with a well tool can include an of outer toroid antenna. The outer toroid antenna can be positionable around an outer housing of the well tool. The communication system can also include an inner toroid antenna positionable within the outer housing of the well tool. The communication system can further include a switch coupled to the outer toroid antenna and the inner toroid antenna. The switch can be operable to enable or disable a wireless communication via the outer toroid antenna or the inner toroid antenna.
US10544671B2 Automated inversion workflow for defect detection tools
A methods for the detection of pipe characteristics. The method may comprise disposing a defect detection tool in a wellbore, processing measurements from the defect detection tool in the wellbore to obtain a well log, storing the well log in a database, importing the well log from the database into inversion software, loading a well plan into the inversion software, determining collar locations on at least one concentric pipe in the wellbore utilizing a collar locator algorithm in the inversion software using the well log and well plan, calibrating a forward model in the inversion algorithm utilizing a calibration algorithm in the inversion software, generating an output log utilizing the inversion algorithm in the inversion software on the inversion zone, and determining false metal loss in the output log using the output log.
US10544670B2 Reluctance sensor for measuring a magnetizable structure in a subterranean environment
A drilling apparatus, sensor, system and method. The drilling apparatus includes a drill bit and a steering controller that steers the drill bit. The drilling apparatus includes a reluctance sensor system that measures changes in magnetic flux. The reluctance sensor includes two or more magnets creating a bucking effect. The drilling apparatus includes a processor in communication with the reluctance sensor that receives the measurements made by the reluctance sensor to determine a distance or direction to a target object. The distance is utilized by the steering controller to steer the drill bit.
US10544666B1 Formation dip geo-steering method
A method of drilling a well within a target stratum. The method can include drilling based upon a target window created from previously collected and/or extrapolated data. Data is collected while drilling and the target window can be adjusted “on the fly” as well as updating and correcting previously collected data. The method can be repeated to ensure optimal drilling efficiency and minimal down time while drilling.
US10544665B2 Method for calculating optimum gel concentration and dilution ratio for fracturing applications
A method of preparing a fracturing slurry comprising a concentrated gel and water, the method comprising preparing a concentrated gel from a polymer and water, diluting the concentrated gel with additional water to form a fracturing carrier fluid at a predefined downhole concentration, preparing a fracturing slurry comprising the fracturing carrier fluid, and pumping the fracturing slurry downhole at or below a predefined maximum slurry rate. The fracturing carrier fluid is formed upon allowing the concentrated gel sufficient residence time to at least partially hydrate.
US10544660B2 Recycle loop for a gas lift plunger
A system and method for operating a gas lift plunger in a well. The method includes determining that the plunger is at a predetermined position in the well, well. The method also includes introducing gas from a compressor into a sales line in response to determining that the plunger is at the predetermined position in the well. The method also includes and introducing the gas from the compressor into the well at a predetermined amount of time after the plunger is determined to be at the predetermined position in the well.
US10544656B2 Active fluid containment for mud tanks
Apparatus, method, and a containment system for a mud tank The system includes a pan extending from a base of the mud tank and configured to receive fluids leaked therefrom, a fluid sensor coupled with the pan, and a pump in fluid communication with the pan, wherein the pump is configured to remove fluid from the pan when the fluid sensor reads a predetermined threshold fluid level in the pan.
US10544650B2 Rotating disk valve for rotary steerable tool
A rotary steerable tool used for directional drilling include a housing, at least one external director, and at least one valve. The external director is hydraulically movable to an extended condition relative to the housing, and the valve selectively directs pressurized fluid from a first side of the valve to the external director on the valve's second side. A first seal of the valve is selectively orientable about an axis and has an inlet, which communicates with the pressurized fluid from the first side. A second seal of the valve disposed adjacent the first seal has an outlet, which communicates the pressurized fluid to the second side at least when aligned with the inlet. A bearing assembly of the valve is disposed at the axis between the seals and has male and female bearing surfaces, which are angled off the axis and are mated with one another.
US10544645B2 Dissolvable composite slips and methods of manufacturing same
A dissolvable composite slip can include at least in part a dissolvable material. A dissolvable composite slip can include at least in part a non-dissolvable metallic material. The dissolvable material should be strong enough to support the non-dissolvable metallic material which serves as teeth to set into the casing during the function of the downhole tool. The dissolvable material can include but is not limited to a polymeric material or a metallic material. At least a part of the slip is able to be set as well as be dissolved.
US10544644B2 Apparatus with crossover assembly to control flow within a well
An apparatus for controlling fluid flow in a well includes an inner tubular member with a flow path formed therethrough and an outer tubular member configured to be positionable about the inner tubular member to define an annulus between the outer tubular member and the inner tubular member. The apparatus further includes a crossover assembly coupled to the inner tubular member and the outer tubular member and configured to enable fluid flow between the flow path of the inner tubular member and an exterior of the outer tubular member, and a flow control device coupled to the crossover assembly and configured to control fluid flow through the crossover assembly.
US10544643B2 Hydraulic fracturing systems and methods
A well stimulation system includes an inlet fluid conduit connected to a manifold, and a first wellhead assembly connected to the manifold, wherein the wellhead assembly includes a frac tree, a wellhead coupled to the frac tree, wherein the wellhead is in fluid communication with a first well, wherein the frac tree of the first wellhead assembly is configured to inlet a stimulation fluid from the manifold to the first well along a first fluid flowpath extending through the frac tree, wherein the frac tree of the first wellhead assembly is configured to outlet well fluid from the first well to the manifold along the first fluid flowpath.
US10544640B2 Multi-cycle pipe cutter and related methods
A downhole cutting tool includes a tool body and a plurality of cutter knife sets, each of the plurality of cutter knife sets configured to extend outwardly to separately perform a pipe cutting operation. A first cutter knife set has a diameter in an extended position larger than a diameter in an extended position of a second cutter knife set. A method includes running the downhole cutting tool into a wellbore, deploying the first set of expandable cutting arms to an extended position and engaging the extended expandable cutting arms with a first work piece, rotating the downhole cutting tool and cutting the first work piece, deploying the second set of expandable cutting arms during a single trip into the wellbore to an extended position and engaging the extended expandable cutting arms with a second work piece, and rotating the downhole cutting tool and cutting the second work piece.
US10544634B2 Pipe handling device
The present invention relates to a tubular handling system for maneuvering tubulars onto or off of a rig and including a tubular grip adapted to engage a variety of tubular sizes.
US10544630B1 Systems and methods for slug mitigation
A system for mitigating slugging in the conveyance of a subterranean resource can include at least one first pipe disposed proximate to a subterranean formation, where the at least one first pipe has a first cavity through which the subterranean resource traverses from the subterranean formation. The system can also include at least one second pipe disposed proximate to field equipment at an operating platform, where the at least one second pipe has a second cavity through which the subterranean resource traverses, where the field equipment is used to extract the subterranean resource. The system can also include a first slug mitigation assembly disposed between the at least one first pipe and the at least one second pipe, where the first slug mitigation assembly includes a first plurality of non-linear segments for reducing accumulation of gas or liquid pockets in the subterranean resource as the subterranean resource flows therethrough.
US10544629B2 Debris management assembly
A debris management assembly including a housing, a mandrel disposed within the housing, a debris sump defined between the mandrel and the housing, and a debris diverter operably connected to the mandrel and positioned to direct debris that encounters the debris diverter into the debris sump.
US10544628B2 Drill bit with self-directing nozzle and method of using same
A self-directing nozzle of a drill bit of a downhole tool and method are disclosed. The drill bit with the nozzle may be used to form a wellbore in a subterranean formation. The drill bit has a passage for fluid to pass through. The nozzle includes a case positionable in the passage of the drill bit and a movable body movably positionable in the case. The movable body has a channel for passage of the fluid therethrough. The channel has a non-linear shape with a channel axis extending therethrough. The channel axis is curved to define a spiral flow path therethrough whereby the fluid passing through the channel facilitates rotation of the movable body within the passage of the drill bit.
US10544626B2 Cutting rate control for an ice drill
A cutting head includes a main body that is attachable to an ice drill shaft at a top side. The main body includes a bottom side that has a bottom peripheral surface. The cutting head includes at least one cutting edge that is disposed on the main body. The cutting edge is configured to perform a cutting operation at the bottom side of the main body. The cutting head includes a cutting rate control pad that is disposed on the bottom side of the main body. The cutting rate control pad extends away from the bottom peripheral surface.
US10544625B2 Multi fluid drilling system
A multi-fluid drilling system 10 drilling is disclosed for drilling a hole or well 11. The system 10 is coupled to a dual wall drill string 12. The drill string 12 is configured to enable separate flow of a first fluid 14 and a second fluid 16. The system 10 has a hammer 22 and a downhole motor 24. Both the hammer 22 and the motor 24 are supported by and are coupled to the drill string 12. The motor 24 is uphole of the hammer 22. The hammer 22 is arranged so that when supported by the drill string 12 the first fluid 14 when flowing through the drill string 12 is able to flow to and power the hammer 22. As the motor 24 is disposed between the hammer 22 and the drill string 12 the first fluid 14 is also able to flow through the motor 24. To this end the motor 24 has a channel 25 to enable the first fluid to flow from the drill sting 12 to the hammer 22. The channel 25 acts as a part of a flow path or conduit for the first fluid 14.
US10544621B2 Roller shade system
A roller shade system comprising a covering material windingly coupled to a roller tube such that rotation of the roller tube causes the covering material to be raised or lowered. A mechanism is coupled to the roller tube to rotate the roller tube and a level adjuster is attached to each end of the roller tube. The level adjuster includes a baseplate with a leveling bar pivotally coupled to the baseplate. A valance assembly to enclose the roller tube, mechanism, and level adjuster, while permitting the fabric through an opening is also provided.
US10544614B2 Grain gate swing arm
A mechanism for precisely controlling a slide gate to provide certain and secure location of a sliding gate in a path of flowable dry bulk material, the mechanism including a rack and pinon gear with a shaft with a diameter hole therethrough for receiving a pin therethrough when the sliding gate is in a desired position. The swing arm is configured to inhibit removal of the pin and thereby prevent unwanted movement of the gate from the desired position. The swing arm is configured for selectively prohibiting accidental and/or intentional but unauthorized removal of the pin depending upon types of objects being placed through the open hole in the swing arm and the first fixed arm open hole.
US10544611B2 Removable hinge assemblies
Hinge assemblies having a tub knuckle, a lid leaf and a hinge pin assembly are provided. The tub knuckle has a base, a first pin holder extending from the base and a second pin holder extending from the base and spaced from the first pin holder. The lid leaf has a mounting plate and a pin holder. The hinge pin assembly is movable between a closed position and an open position, and includes a hinge pin and a retainer assembly that can be used to lock the hinge pin assembly in the closed and open positions.
US10544609B2 Cam-operated latch assembly
A latch assembly is disclosed that has a latch, a locking lever having locked and unlocked positions, and a detent lever having engaged and disengaged positions. The locking lever is configured to secure the latch in the closed position when the locking lever is in the locked position and the detent lever is configured to provide a detent function when the detent lever is in the engaged position. In certain aspects, the latch assembly includes a single motor and cam assembly having three configurations, wherein the locking lever and detent lever are respectively in the unlocked and disengaged positions while in the first configuration, in the unlocked and engaged positions while in the second configuration, and in the locked and engaged positions while in the third configuration.
US10544600B1 Ballasted attachment for temporary truss structures
Ballasted Attachment for Temporary Truss Structures or BATTS are used to support Temporary structures typically built in the live event, trade show, and special event marketplace. BATTS provide a quickly deployed, leveled and stable base for which one can mount aluminum box truss too. This allows tower construction equal to the capacity of the truss itself and a flexible outrigger attachment in which many engineering requirements can be achieved. BATTS provide a ballast point to resist the overturn moment and uplift moment of concert roofs and other system that are exposed to environmental conditions. BATTS are constructed from steel and aluminum and possess substantial self-weight.
US10544599B2 Integrated, multi-level airport terminal system
The invention is directed to an integrated, multi-level airport terminal system with a plurality of cells disposed in an adjoining relation to one another. Each of the plurality of cells have a plurality of levels. At least one ramp member is disposed through each of the plurality of cells. The ramp member is disposed through an internal environment of each of the plurality of cells for transiting at least one aircraft through at least one cell of the plurality of cells in a sequential arrangement. Each of the plurality of cells are disposed in the adjoining relation to one another to define at least one row. At least one row is further disposed in a corresponding relation to at least another row. The invention is also related to a method of transiting at least one aircraft arriving in and departing out of the integrated, multi-level airport terminal system.
US10544596B2 Anti-slip, liquid management flooring surface cover article and method of manufacture
An anti-slip, liquid management cover article for a flooring surface. The article includes a film defining a working face. A microstructured surface is formed at the working face, and includes a plurality of primary ridges and capillary microchannels each having a bottom surface. Each primary ridge is an elongated body having a length. A shape of a portion of at least one of the primary ridges is non-uniform in a direction of the length. The capillary microchannels facilitate spontaneous wicking of liquid. With this construction, the non-uniform shape establishes an elevated coefficient of friction at the working face as measured in multiple directions. The cover article minimizes the risk of pedestrian slippage, even in the presence of water or other liquids.
US10544588B2 Masonry reinforcement structure comprising parallel assemblies of grouped metal filaments and a polymer coating
The invention relates to a masonry reinforcement structure (100) comprising at least two assemblies (102) of grouped metal filaments, at least one positioning element (104) for positioning the assemblies (102) of grouped metal filaments in a predetermined position and a polymer coating (110) for securing the assemblies (102) of grouped metal filaments in this predetermined position. The invention also relates to a method of manufacturing such masonry reinforcement structure (100) and to a roll comprising such a masonry reinforcement structure (100). The invention further relates to masonry reinforced with such masonry reinforcement structure (100) and to a method to apply such masonry reinforcement structure (100).
US10544587B2 Composite wall panel
A composite wall panel comprising a panel frame and an insulating layer disposed therein, and a wall assembly comprising a plurality of the composite wall panels that are vertically jointed to one another. Various embodiments and combinations of embodiments are provided.
US10544580B2 System, method and apparatus for corner siding
A corner siding product may include a plurality of panels. Each panel may include a front face with a simulated pattern and an inner wall formed along a perimeter of the panel. The corner siding product may further include a clip that is configured engage each panel to hold the panels together and form a corner.
US10544577B2 Member-to-member laminar fuse connection
A member-to-member planar connection bracket that includes multiple repeated fuse element configurations that each provide a pre-determined inelastic load-carrying capacity and a reliable inelastic deformation capacity upon development of one or more inelastic hinge locations within the fuse elements. The fuse configurations are interconnected in series such that the total deformation accommodated between first end of the bracket and second end of the bracket is the sum of deformations accommodated by the individual fuse configurations. Multiple brackets are configured in laminar configurations and interconnected to create a connection assembly that provides increased strength or increased deformation capacity as compared to an individual bracket. The connection assembly is used to connect a first structural member and second structural member. The pre-determined maximum inelastic load-carrying capacity of the assembly is less than the elastic load-carrying capacity of the first structural member and the second structural member.
US10544574B2 Clean toilet and accessories
A toilet that includes a bowl; a tank having a sidewall and a bottom defining a reservoir; a container located inside the reservoir and configured to contain a chemical compound that mixes with water to form a cleaning compound; a connector for coupling the container to the sidewall; and a flush valve. The connector has a bracket coupled to the container, a threaded protrusion that extends from the bracket into a hole in the sidewall of the tank, and a threaded fastener having a threaded body and a head, which is larger radially than the threaded body such that the head contacts an outside of the sidewall in a secured position in which the threaded body threads to the threaded protrusion. The flush valve is fluidly connected to the container to introduce the cleaning compound into the bowl through an outlet in the bottom during a cleaning cycle.
US10544572B2 Overflow cap and assembly
An overflow assembly including an overflow cap and a locking ring is described that allows liquid (e.g., water) being received or collected in a plumbing fixture (e.g., a bathtub) to flow into an overflow pipe in an effective, aesthetically pleasing manner using components that are easier to install than some conventional solutions. The locking ring has a threaded inner surface that is designed to be threaded onto an externally threaded end of the overflow pipe that is extended through a wall of the plumbing fixture to secure the overflow pipe with respect to the wall. The overflow cap may then be pressed onto the externally threaded end of the overflow pipe, such that it engages the externally threaded end via engagement tabs. The overflow cap can be removed from the end of the overflow pipe by rotating the cap to unthread it from the threaded end of the overflow pipe.
US10544569B2 Externally adjustable flow management valve assembly and system
A system and valve assembly that is adapted to increase the efficiency of an upstream water meter. By way of the valve assembly entrained water bubbles can be removed from a water supply. This, in turn, increases the density of the water running through the water meter. This ensures that the water meter is not inaccurately including entrained air as metered water. The result is more accurate water readings and reduced utility bills. The assembly can be externally adjusted using an adjustment tool so as to increase or decrease the tension on an interior spring which, in turn, increases or decreases the rate at which the interior block oscillates.
US10544562B2 Dragline bucket
A dragline bucket comprises a base member, a first side member extending from the base member and including a first top edge, a second side member extending from the base member, and a rear member extending from the base member and including a second top edge, a mouth for receiving material into the bucket, and a first beveled wall extending from the first side member forming a first compound angle with the base member and a second beveled wall extending from the rear member proximate the first beveled wall forming a second compound angle with the base member.
US10544559B2 Pier and mat foundation fortification and monitoring system
A method of retrofitting a pier/mat foundation and assemblies for same. Retrofitting includes attaching fortification brackets around an outside of a pier of a pier/mat foundation of a wind turbine structure. Fortification rod bottom ends are secured to the mat outside of the pier and near a location under an outer portion of each installed fortification bracket. Fortification rod top ends are attached to openings in outer portions of the fortification brackets. A retrofitting foundation fortification assembly includes a top bracket with at least one hole to receive a foundation anchor holding a wind turbine tower to a pier/mat foundation; a vertical portion dependent from the top bracket near a vertical face of the pier when the at least one hole receives foundation anchors; and a fortification rod hole located outside of the pier when the at least one hole receives the foundation anchors.
US10544557B1 Waste scooper
A biodegradable and disposable waste scooper includes a waste scoop, a waste bag, and a securing mechanism. The waste scoop is fully engulfed by the waste bag to keep animal wastes from directly contacting with user's hands or cloth during the cleaning process. The waste bag includes a securing mechanism to seal the waste bag's opening. After the user scoop up animal wastes, the user may tilt the waste scoop and move animal wastes into the waste bag for storage and seal the waste bag's opening with the securing mechanism. The user may reopen the waste bag to dump animal wastes from the waste bag for disposal or may dispose the entire invention without burdening the environment.
US10544555B1 Roadway barrier apparatus
Roadway barrier apparatus including roadway barrier modules disposed end to end and pivotally connected together by a pivot pin positioned in aligned apertures of connector brackets at the ends of the modules, the pivot pin having a groove and a spring biased hinge pusher member positionable in the groove to limit upward movement of the pivot pin.
US10544550B2 Device and method for monitoring process data in road finishing
A wearable computer is used for monitoring process data in road finishing. The wearable computer receives process data of the road finishing process. In the event of process data lying outside a predetermined range, the wearable computer effects alerting of the wearer of the wearable computer.
US10544548B2 Expansion joint seal system with spring centering and ribs with protuberances
A system which creates a durable seal between adjacent horizontal panels, including those that may be curved or subject to temperature expansion and contraction or mechanical shear. The durable seal system incorporates a plurality of ribs, a flexible member between the cover plate and the ribs and may incorporate a load transfer plate to provide support to the rib from below, and/or cores of differing compressibilities.
US10544542B2 Control method for laundry treating apparatus
Disclosed is a control method for laundry treating apparatus configured to perform a dry cycle for clothes by operating a heat pump comprising: a measuring step for measuring a temperature of a refrigerant and a temperature of air which pass through an evaporator to exchange heat; a comparing step for comparing a difference between the measured temperatures of the refrigerant and air with a preset reference temperature; and an adjusting step for adjusting an opening degree of the expansion valve according to the result of the comparing step.
US10544541B2 Clothes dryer
Disclosed is a clothes dryer. The clothes dryer includes a drum; an air supply/exhaust unit for supplying/exhausting drying air to/from the drum; a burner for heating the drying air; a temperature sensor for detecting an exhaust temperature; and a heating control unit for performing a temperature adjustment process of stopping the burner when the exhaust temperature reaches an upper limit temperature and restarting the burner after a time point when the exhaust temperature decreases to a re-ignition temperature. The heating control unit has a delay time inserting portion, which inserts a delay time between the time when the exhaust temperature decreases to a lower limit temperature and the time when the burner is restarted. The delay time is increased every time the temperature adjustment process is repeated intermittently.
US10544540B2 Drying machine
A drying machine is provided that may include a drum configured to receive items to be dried, an air circulating device that circulates air through the drum, a motor that drives a drying fan for air circulation, a condenser that condenses moisture in circulating air introduced from the drum, a heater that heats the circulating air introduced from the condenser, and a base, which is provided under the drum to support the drum and which may form a lower portion of the drying machine. The air circulating device may include a condensation duct, which may change in structure in order to accommodate different types of condensers based on how the respective condensers perform heat exchange. The base may include a condensation duct mount having a consistent shape and size to accommodate the condensation duct regardless of a shape of the condensation duct.
US10544536B2 Laundry washing machine and method for controlling a laundry washing machine
Laundry washing machine (1) has an outer casing (2), a washing tub (3), arranged inside the casing (2), and a rotatable drum (4), arranged in axially rotating manner inside the washing tub (3) and designed to receive laundry to be washed The machine also has a detergent dispensing assembly (12), designed for supplying detergent/water into the washing tub (3), a water softening system (14), designed to receive fresh water from a water mains (13) and configured to reduce the hardness degree of the fresh water in order to supply softened water to the detergent dispensing assembly (12) and/or to the washing tub (3) during one or more softened water laundry wash phases. The machine also has a heating device (11) to heat the water loaded in the washing tub (3) so as to regulate the temperature of the loaded water, a control panel (28) configured to allow the operator to input information indicative of a washing course to be performed, wherein the washing course has one or more softened water laundry wash phases, and a controller (15) configured to control the heating device (11) to regulate the temperature of the water loaded in the washing tub (3) based on the softened water laundry wash phase/s of the laundry washing course.
US10544532B2 Laundry treatment apparatus and method of controlling the same
A method of controlling a laundry treatment apparatus, the method including: determining whether bubbles have been generated in a tub of the laundry treatment apparatus in a state in which a second washing apparatus of the laundry treatment apparatus is operated based on a sequence of operations; and based on a determination that bubbles have been generated, reducing bubbles by (i) adding at least one first operation to the sequence of operations or (ii) replacing at least one second operation of the sequence of operations, is disclosed.
US10544527B2 Fabric and clothing having flame retardancy and high visibility
A fabric includes an A side mainly configured by yarns made of fibers capable of being dyed within color coordinates and in a luminance factor defined in ISO 20471; and a B side mainly configured by blended spinning yarns made of flame-retardant fibers having a self-extinguishing property and non-melting fibers.
US10544522B2 Thread draw-off nozzle for an open-end spinning device
A thread draw-off nozzle for an open-end spinning device includes a nozzle insert configured to deflect a yarn produced by the open-end spinning device. A nozzle frame fixes the thread draw-off nozzle in the open-end spinning device. The nozzle frame includes a cylindrical shank, which has a centering diameter and a length that is shorter than half the centering diameter.
US10544519B2 Method and apparatus for surface preparation prior to epitaxial deposition
During a pre-treat process, hydrogen plasma is used to remove contaminants (e.g., oxygen, carbon) from a surface of a wafer. The hydrogen plasma may be injected into the plasma chamber via an elongated injector nozzle. Using such elongated injector nozzle, a flow of hydrogen plasma with a significant radial velocity flows over the wafer surface, and transports volatile compounds and other contaminant away from the wafer surface to an exhaust manifold. A protective liner made from crystalline silicon or polysilicon may be disposed on an inner surface of the plasma chamber to prevent contaminants from being released from the surface of the plasma chamber. To further decrease the sources of contaminants, an exhaust restrictor made from silicon may be employed to prevent hydrogen plasma from flowing into the exhaust manifold and prevent volatile compounds and other contaminants from flowing from the exhaust manifold back into the plasma chamber.
US10544514B2 Gas diffusion device and electrochemical hydrogen pump
A gas diffusion device includes a first gas diffusion layer that diffuses gas and is formed of metal and at least one first metal plate that is provided on at least one main surface of the first gas diffusion layer and includes a manifold hole through which gas flows and a gas flow path which communicates with the manifold hole, and the gas flow path passes through the first metal plate.
US10544511B2 Device for generating oxygen
A device for generating oxygen comprising at least one reaction chamber for housing a composition for generating oxygen, the composition comprising a combination of constituents consisting of at least one oxygen source, at least one ionic liquid, and at least one metal oxide compound, means for maintaining at least one of the oxygen source, the ionic liquid and the metal oxide compound physically separated from the remaining constituents, means for establishing physical contact of the oxygen source, the ionic liquid and the metal oxide compound, and means for allowing oxygen to exit the reaction chamber, wherein the metal oxide compound is an oxide of a single metal or of two or more different metals, said metal(s) being selected from the metals of groups 2 to 14 of the periodic table of the elements, and wherein the oxygen source comprises a peroxide compound.
US10544510B2 Electrodeposited, nanolaminate coatings and claddings for corrosion protection
Described herein are electrodeposited corrosion-resistant multilayer coating and claddings that comprises multiple nanoscale layers that periodically vary in electrodeposited species or electrodeposited microstructures. The coatings may comprise electrodeposited metals, ceramics, polymers or combinations thereof. Also described herein are methods for preparation of the coatings and claddings.
US10544509B2 Film forming device
In a film forming device, a mist spray head includes: an inert gas spray part between a raw material solution spray nozzle and a reaction material spray nozzle; and an inert gas spray part between the raw material solution spray nozzle and a reaction material spray nozzle. Accordingly, an inert gas ejection port is provided between a raw material solution ejection port and a reaction material ejection port, and an inert gas ejection port is provided between the raw material solution ejection port and a reaction material ejection port.
US10544493B2 Aluminum alloys with high strength and cosmetic appeal
The disclosure provides aluminum alloys having varying ranges of alloying elements and properties. The aluminum alloys have a wt % ratio of Zn to Mg from 2.5 to 3.5.
US10544491B2 Method for minimizing the global production cost of long metal products and production plant operating according to such method
A method for producing long metal products includes the steps of receiving long intermediate products traveling on respective continuous casting lines, to an exit area, and subsequently introducing products from the exit area into a production plant having known layout parameters; the production plant has a rolling mill for rolling the products; interconnected production lines between the exit area of the casting machine and the rolling mill, the production lines define production paths or routes; and a first and a second heating devices. The method associates a mathematical model to the production plant for dynamically calculating a reference value, or Global Heating Cost Index, correlated to heating devices; automatically determining for the intermediate products the production path or route that minimizes the reference value, or Global Heating Cost Index; and eventually automatically routing each of the products along the determined production path which minimizes the reference value, or Global Heating Cost Index.
US10544489B2 Highly formable high-strength steel sheet, warm working method, and warm-worked automobile part
A high-strength steel sheet has a chemical composition including 0.05% to 0.3% of C, 1% to 3% of Si, 0.5% to 3% of Mn, 0% to 0.1% of P, 0.001% to 0.1% of Al, and 0.002% to 0.03% of N, in mass percent; further includes iron and impurities; and has a structure including 50% to 90% of bainitic ferrite, 5% to 20% of retained austenite (γR), a total of 10% to 50% of martensite and the retained austenite, and 0% to 40% of polygonal ferrite, in area percent based on the entire structure. The retained austenite has a carbon content (CγR) of 0.5% to 1.2% by mass, an average equivalent circle diameter of 0.2 to 2 μm, and an average aspect ratio (maximum diameter/minimum diameter) of less than 3.0. The high-strength steel sheet excels both in elongation and deep drawability while having a strength of 980 MPa or more.
US10544471B2 Methods for sequence-directed molecular breeding
The present invention provides breeding methods and compositions to enhance the germplasm of a plant by the use of direct nucleic acid sequence information. The methods describe the identification and accumulation of preferred nucleic acid sequences in the germplasm of a breeding population of plants.
US10544456B2 Systems and methods for nucleic acid sequencing
Provided herein are systems and methods for processing and analyzing nucleic acids and other biomolecules. Methods may include processing nucleic acid molecules in an emulsion of droplets. Methods of analyzing nucleic acid molecules may include coupling nucleic acids to a bead or other support. Methods may include analysis of nucleic acid molecules using a redox mediator. In some cases, analysis of the nucleic acid molecule includes determining a nucleotide sequence of the nucleic acid molecule.
US10544452B2 Method and use of nucleic acid isothermal amplification via a polymerase spiral reaction
A nucleic acid isothermal amplification method is based on a polymerase spiral reaction using only one pair of primers. The method employs a self-spiraling amplification method, and has a high amplification efficiency.
US10544451B2 Vesicular linker and uses thereof in nucleic acid library construction and sequencing
Provided are a vesicular linker and a single-chain cyclic library constructed by using the linker. The library can be used for RNA sequencing and other sequencing platforms dependent on a single-stranded cyclic library, and has the advantages of high throughput sequencing, high accuracy and simple operations.
US10544449B2 Bis-biotinylation tags
Multi-biotinylated reactants are provided which can be used in divalent complexes for various applications such as colocalization, labeling, immobilization, and purification. Methods for constructing, purifying, and using the bis-biotinylated reactants are also provided. In certain embodiments, two bis-biotinylated reactants are bound to a single streptavidin tetramer to provide a complex having a 1:1 stoichiometry with respect to the bis-biotinylated reactants.
US10544448B2 Methods for sequence-directed molecular breeding
The present invention provides breeding methods and compositions to enhance the germplasm of a plant by the use of direct nucleic acid sequence information. The methods describe the identification and accumulation of preferred nucleic acid sequences in the germplasm of a breeding population of plants.
US10544447B2 DNA quality assessments using repetitive sequences
The present disclosure provides methods, arrays and kits for assessing the quality of genomic DNA samples, especially those obtained from formalin-fixed paraffin-embedded (FFPE) samples. The methods, arrays and kits provided herein use primer pairs specific to regions in the genomes of the organisms from which genomic DNA samples are obtained that have identical or nearly identical copies distributed across multiple chromosomes.
US10544446B1 Method of preparing clinical samples for nucleic acid amplification
The present disclosure is a method of preparing a clinical sample comprising host cells, microbes, proteins and a polyanionic polymer nucleic acid amplification inhibitor.
US10544433B2 Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing
Many studies have shown that CRISPR-Cas nucleases can tolerate up to five mismatches and still cleave; it is hard to predict the effects of any given single or combination of mismatches on activity. Taken together, these nucleases can show significant off-target effects but it can be challenging to predict these sites. Described herein are methods for increasing the specificity of genome editing using the CRISPR/Cas system, e.g., using RNA-guided Foki Nucleases (RFNs), e.g., Fokl-Cas9 or Foki-dCas9-based fusion proteins.
US10544432B2 Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
Adeno-associated virus rh.20 sequences, vectors containing same, and methods of use are provided.
US10544430B2 Vesicular stomatitis virus and virus rescue system
The present relation relates to recombinant vesicular stomatitis virus for use as prophylactic and therapeutic vaccines as well as the preparation and purification of immunogenic compositions which are formulated into the vaccines of the present invention.
US10544427B2 Transgenic mouse model for dementia
Disclosed is a vector pair for screening tau oligomer formation, a mouse embryo introduced with the vector pair, a transgenic model mouse of neurological disease, obtained from the mouse embryo, and a method of screening a tau oligomer formation inhibitor candidate using the transgenic model mouse. More specifically, the present invention provides vector pair for screening tau oligomer formation, comprising: a first vector comprising a first tau gene, a first fluorescence protein gene and a first neuron-specific promoter; and a second vector comprising a second tau gene, a second fluorescence protein gene and a second neuron-specific promoter, wherein a protein expressed from the first fluorescence protein gene and a protein expressed from the second fluorescence protein gene bind to each other to display fluorescence, by association between a protein expressed from the first tau gene and a protein expressed from the second tau gene.
US10544426B2 Methods of using ALS inhibitor herbicides for control of unwanted vegetation in ALS inhibitor herbicide tolerant beta vulgaris plants
Present invention relates to the use of the ALS inhibitor herbicides for controlling unwanted vegetation in ALS inhibitor herbicide tolerant Beta vulgaris plants, more especially, present invention relates to the use of ALS inhibitor herbicides for control of unwanted vegetation in Beta vulgaris, preferably in sugar beet growing areas in which the Beta vulgaris, preferably sugar beet comprise a mutation in codon 1705-1707 of an endogenous ALS gene encoding an ALS protein containing an amino acid that is different from tryptophan at position 569, preferably the tryptophan is substituted by leucine.
US10544425B2 Plant having increased resistance or susceptibility to 4-HPPD inhibitor
By a QTL analysis and so forth using 4-HPPD inhibitor-susceptible rice and 4-HPPD inhibitor-resistant rice, a hypothetical gene (HIS1 gene) of an iron/ascorbate-dependent oxidoreductase gene located on a short arm of chromosome 2 of rice has been identified as a 4-HPPD inhibitor-resistance gene. Further, it has also been revealed that a homologous gene (HSL1 gene) of the HIS1 gene is located on chromosome 6 of rice. Furthermore, it has been found out that utilizations of these genes make it possible to efficiently produce a plant having increased resistance or susceptibility to a 4-HPPD inhibitor and to efficiently determine whether a plant has resistance or susceptibility to a 4-HPPD inhibitor.
US10544421B1 System and method for creating crystals of human acetylcholinesterase with open active sites
A system and method for creating crystals from human acetylcholinesterase. The crystals can then be analyzed using X-ray crystallography. A segment of DNA for human acetylcholinesterase is isolated that includes the codon sequence GAGGGC. A polyhistidine tag is inserted between codon GAG and codon GGC to produce a recombinant acetylcholinesterase construct. The recombinant acetylcholinesterase construct is used to transfect cells on a prepared growth medium. The growing cells secrete a portion of the recombinant acetylcholinesterase construct. The secreted portion is concentrated and the tag cleaved. The concentrate is then buffered and used to form crystals.
US10544419B2 PDGF and VEGF aptamers having improved stability and their use in treating PDGF and VEGF mediated diseases and disorders
Aptamers having improved stability against nucleases that bind PDGF and aptamers that bind VEGF are provided. In addition, aptamer constructs comprising a PDGF aptamer and a VEGF aptamer are provided. Pharmaceutical compositions comprising the aptamers and aptamer constructs are provided, as well as methods of treating conditions using the aptamers and aptamer constructs.
US10544414B2 Two-cassette reporter system for assessing target gene translation and target gene product inclusion body formation
The present invention relates to a dual cassette reporter system capable of assessing target gene translation and target gene product folding. The present invention further relates to vectors and host cells comprising the dual cassette reporter system. In addition the invention relates to the use of the dual cassette reporter system for assessing target gene translation and target gene product folding.
US10544409B2 Hexuronate C4-epimerase mutant with improved conversion activity, and method for producing D-tagatose by using same
A hexuronate C4-epimerase with improved conversion activity and a method for producing D-tagatose using the hexuronate C4-epimerase. The hexuronate C4-epimerase includes an amino acid sequence set forth in SEQ ID NO: 1, in which serine (S) at position 125, serine (S) at position 185, valine (V) at position 267, serine (S) at position 268, threonine (T) at position 272, tryptophan (W) at position 306, arginine (R) at position 386 and tyrosine (Y) at position 403 from an N-terminal of hexunorate C4-epimerase are mutated.
US10544408B2 Purification process for isolation and commercial production of recombinant TNK-tPA tenecteplase
The present invention relates to a novel process of isolating and purifying tissue plasminogen activator and its variants more specifically TNK-tPA from CHO cells and describes an industrially applicable, simple, cost effective, robust and highly efficient process of TNK-tPA purification.
US10544402B2 Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs
The present disclosure provides engineered transaminase polypeptides for the production of amines, polynucleotides encoding the engineered transaminases, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases to prepare compounds useful in the production of active pharmaceutical agents.
US10544399B2 Highly efficient influenza matrix (M1) proteins
This invention discloses a method of increasing production of virus-like particles comprising expressing an avian influenza matrix protein. The invention also comprises methods of making and using said VLPs.
US10544392B2 Methods of isolating T cells and T cell receptors having antigenic specificity for a cancer-specific mutation from peripheral blood
Disclosed are methods of isolating T cells and TCRs having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation. Also disclosed are related methods of preparing a population of cells, populations of cells, TCRs, pharmaceutical compositions, and methods of treating or preventing cancer.
US10544383B2 Dishwashing detergent composition comprising a branched anionic/amine oxide surfactant mixture
Dishwashing detergent composition comprising an anionic surfactant system comprising an average percentage of branching of greater than or equal to 5% to less than 24%; and at least one branched anionic surfactant derived from a 100% branched alcohol.
US10544381B2 Methods and apparatus for producing alkyl esters from a reaction mixture containing acidified soap stock, alcohol feedstock, and acid
Embodiments herein relate to the production of alkyl esters from acidified soap stock. In an embodiment, a process for producing alkyl esters is provided. The process can include mixing acidified soap stock with an alcohol, water, carbon dioxide, and/or carbon monoxide, to form a reaction mixture, and contacting the reaction mixture with a catalyst under supercritical conditions for the alcohol, the catalyst including a metal oxide. Other embodiments are also included herein.
US10544371B2 Channel reactors
Described is an industrial scale chemical reactor or reactor containing a shell having an inner wall, and at least one channel inside the shell. The shell has a circular, square, or rectangular cross-sectional area. All of the internal dimensions of the channel are greater than 10 mm, and optionally less than 50 mm. The channel has a rectangular cross-sectional area, and contains a catalyst bed containing catalyst particles and/or pieces containing catalyst particles packed inside the channel. The reactor has improved shell volume utilization, catalyst loading capacities, heat exchange efficiency, process intensification, or combinations thereof, compared to currently existing reactors. Exothermic reactions, such as the Fischer-Tropsch synthesis can be performed inside the channels of the reactor. Also described are methods of making the reactor.
US10544368B2 Rapid thermal conversion of biomass
The present invent provides improved rapid thermal conversion processes for efficiently converting wood, other biomass materials, and other carbonaceous feedstock (including hydrocarbons) into high yields of valuable liquid product, e.g., bio-oil, on a large scale production. In an embodiment, biomass material, e.g., wood, is feed to a conversion system where the biomass material is mixed with an upward stream of hot heat carriers, e.g., sand, that thermally convert the biomass into a hot vapor stream. The hot vapor stream is rapidly quenched with quench media in one or more condensing chambers located downstream of the conversion system. The rapid quenching condenses the vapor stream into liquid product, which is collected from the condensing chambers as a valuable liquid product. In one embodiment, the liquid product itself is used as the quench media.
US10544366B2 Liquid crystal composition and liquid crystal display device
Provided are a liquid crystal composition satisfying at least one of characteristics including a high maximum temperature, a low minimum temperature, small viscosity, suitable optical anisotropy and large negative dielectric anisotropy, or the liquid crystal composition having a suitable balance regarding at least two of the above characteristics; and an AM device including the composition. The liquid crystal composition contains a specific compound having large negative dielectric anisotropy as a first component, and a specific compound having small viscosity as a second component, and may contain a specific component having high maximum temperature or small viscosity as a third component, a specific component having negative dielectric anisotropy as a fourth component, or a specific compound having a polymerizable group as an additive.
US10544364B2 Soil stabilizer carrier
A method for applying a water soluble soil stabilizer to soil wherein the soil stabilizer is added to a solid carrier.
US10544361B2 Pyridines and derivatives thereof as components for use in optoelectronic components
The invention relates to an organic molecule comprising a structure of formula 1 and to the use thereof in optoelectronic components. wherein: X is SO2, CO or a C—C single bond; m is 0 or 1; n is 1, 2 or 3; r is 0 or 1; s is 0 or 1; LG is a divalent linker group, selected from: or LG is an element-element single bond.
US10544358B2 Coated and cured proppants
Solid proppants are coated with a coating that exhibits the handling characteristics of a pre-cured coating while also exhibiting the ability to form particle-to-particle bonds at the elevated temperatures and pressures within a wellbore. The coating includes a substantially homogeneous mixture of (i) at least one isocyanate component having at least 2 isocyanate groups, and (ii) a curing agent comprising a monofunctional alcohol, amine or amide. The coating process can be performed with short cycle times, e.g., less than about 4 minutes, and still produce a dry, free-flowing, coated proppant that exhibits low dust characteristics during pneumatic handling but also proppant consolidation downhole for reduced washout and good conductivity. Such proppants also form good unconfined compressive strength without use of an bond activator, are substantially unaffected in bond formation characteristics under downhole conditions despite prior heat exposure, and are resistant to leaching with hot water.
US10544347B2 Fracturing fluids comprising alkanolamine borates as crosslinkers for polysaccharides
A method for formulating a hydraulic fracturing fluid composition with increased viscosity and resistance to degradation at increased temperature and pressure. The method includes preparing an alkanolamine borate formulation compatible for mixing with a hydraulic fracturing fluid comprising polysaccharides; preparing the hydraulic fracturing fluid comprising polysaccharides; and mixing the alkanolamine borate formulation with the hydraulic fracturing fluid, such that the alkanolamine borate formulation causes crosslinking of the hydraulic fracturing fluid.
US10544342B2 Thermally conductive resin composition
Provided is a thermally conductive resin composition having a specific gravity of 1.4-2.0 and an In-Plane thermal conductivity of 1 W/(m·K) or higher, and containing at least (A) 30-90% by mass of a thermoplastic resin, (B) 9-69% by mass of an inorganic filler having a thermal conductivity of 1 W/(m·K) or higher, and (C) 0.05-10% by mass of a crystallization accelerator.
US10544337B2 Autobody repair formulation with improved control of work time and cure time at extreme ambient air temperatures
An Additive Package is provided to adjust the cure properties of a two-part bonding filler across a temperature range of from 4 and 44 degrees Celsius. A low temperature additive speeds a cure rate between 4 and 15 degrees Celsius and a high temperature additive slows down a cure rate between 25 and 44 degrees Celsius. The amount of Additive Package is varied to account for the desired cure properties. The Additive Package includes a first unsaturated polyester resins with an average degree of unsaturation of 70-100 percent based on total acid and anhydride monomer content. A process for repairing a vehicle body is provided using the Additive Package. A kit for accomplishing repairs in an after-market repair setting is also provided.
US10544335B2 Tackifier and a continuous process for producing the tackifier
A rosin dispersion is a reaction product of, by dry weight based on total dry weight of the rosin dispersion, from 80% to 98% a rosin resin, and from 2% to 20% a dispersant. The rosin resin is processed by at least one method of a) modification, b) hydrogenation or disproportionation, and c) polymerization or esterification from raw material rosins. The dispersant is selected from C18-C32 aliphatic carboxylic acids, olefin (meth) acrylic acid copolymers, and other acid/anhydride modified polymers. A continuous process for preparing the rosin dispersion and an adhesive formulation comprising the rosin dispersion are also included.
US10544332B2 Slurry composition and method of use
A slurry composition for use in chemical-mechanical polishing sapphire substrates and includes an alkaline pH adjuster and an accelerant.
US10544329B2 Polysiloxane formulations and coatings for optoelectronic applications
A crosslinkable composition includes a first silicon-containing resin comprising alkyl groups and alkyl groups and a second silicon-containing resin comprising alkyl groups. The first silicon-containing resin has a weight average molecular weight from 1000 AMU to 10,000 AMU. The second silicon-containing resin has a weight average molecular weight from 900 AMU to 5000 AMU. The composition further includes at least one solvent and at least one heat-activated catalyst.
US10544326B2 Low temperature curing coating composition containing sag control agent and use thereof
The present disclosure is directed to a coating composition for producing coatings sag-free at high coating thicknesses, being quick dry and having good appearance. This disclosure is further directed to a coating composition comprising a crosslinking activator comprising: a) one or more alkylated melamines that are essentially unreactive to a polyisocyanate, and b) a polyurea sag control agent formed by reacting an amine and an isocyanate in the presence of the alkylated melamines. The coating composition can be used to form coating layers having a sag-free wet coating thickness in a range of from 10 to 36 mil (about 0.25 to 0.91 mm). The coating composition can be particularly suitable for vehicle coatings.
US10544325B2 Reduced salt precipitation in carbohydrate containing binder compositions
Aqueous binder compositions with reduced rates of salt precipitation are described. The compositions may include a carbohydrate and a sequestrant for sequestering one or more multivalent ions (e.g., Ca2+, Mg2+, Ba2+, Al3+, Fe2+, Fe3+, etc.). The sequestrant reduces a precipitation rate for the multivalent ions from the aqueous binder composition. Methods of reducing salt precipitation from a binder composition are also described. The methods may include the steps of providing an aqueous binder solution having one or more carbohydrates. They may also include adding a sequestrant for one or more multivalent ions to the aqueous binder solution. The sequestrant reduces a precipitation rate for the multivalent ions from the binder composition.
US10544324B2 Noncovalent bond-modified carbon structure, and carbon structure/polymer composite comprising same
According to the present invention, a noncovalent bond-modified carbon structure has advantages of: enabling the control of properties by controlling intervals between carbon structures according to the size and structure of a compound represented by Chemical Formula 1, which is inserted and adsorbed between the carbon structures; and enabling uniform dispersion in a polymer matrix without a change in intrinsic properties. In addition, a carbon structure/polymer composite comprising the modified carbon structure and a polymer matrix is simply manufactured and readily layered due to excellent orientation when forming a cured coating film, and thus can be useful for manufacturing a steel sheet having remarkable heat radiation, surface polarity, electrical properties and the like.
US10544317B2 Thermoformable conductive inks and coatings and a process for fabrication of a thermoformed device
Thermoformable inks and coatings, such as conductive inks and coatings, are provided. These inks and coatings can be used in printed electronic thermoformed devices. These conductive inks and coatings are suitable to be used as one or more printed layers of a printed electronic device printed with multiple layers of inks and/or coatings (printed stacked array). Methods of fabricating printed electronic devices using the thermoformable inks and coatings are also provided.
US10544316B2 Multifunctional coated powders and high solids dispersions
A coated powder comprises (a) nanoparticles, and (b) a coating, on the surface of the nanoparticles. The coating comprises (1) silica moieties, (2) organo oxysilane moieties selected from the group consisting of mono-organo oxysilane moieties, bi-organo oxysilane moieties and tri-organo oxysilane moieties, and (3) poly(dialkyl)siloxane moieties.
US10544313B2 Method and apparatus of applying light and heat to quantum dots to increase quantum yield
A method of increasing photo-luminescent quantum yield (PLQY) of QDs to be used as down-converters placed directly on an LED chip includes synthesizing a plurality of quantum dots, applying energy to the plurality of quantum dots to increase PLQY of the plurality of quantum dots, dispensing the plurality of quantum dots onto the LED chip, and curing the LED chip.
US10544312B2 Marine coatings
Marine coatings including cationic polymers hydrolyzable to nonfouling zwitterionic polymers, coated marine surfaces, and methods for making and using the marine coatings.
US10544310B2 Hydraulic transfer film and method for manufacturing decorated molded article using same
Provided are a hydraulic transfer film capable of manufacturing a decorated molded product that expresses a design with a concavo-convex feeling by a hydraulic transfer method and having excellent transfer processability and a method for manufacturing a decorated molded product using the same. The hydraulic transfer film includes a water-soluble film having thereon a design layer, wherein the design layer has a low-gloss portion and a high-gloss portion; the low-gloss portion and the high-gloss portion are present at least within a plane on the water-soluble film side of the design layer; the low-gloss portion contains a binder resin and a deglossing agent; and the high-gloss portion is composed of a resin composition containing an acrylic polymer polyol and/or a cured product thereof.
US10544309B2 Photoluminescent pigment; cosmetic, paint composition, and resin composition containing same; and bright pigment production method
A bright pigment of the present invention is a bright pigment including flaky particles and a metal oxide layer covering each surface of the flaky particles. The metal oxide layer has a thickness variation coefficient (standard deviation of thickness of the metal oxide layer/average thickness of the metal oxide layer) of 20% or less. The bright pigment preferably contains a sodium component, and the sodium component is Na2O. The content of Na2O in the flaky particles is 3% by mass or more and less than 9.5% by mass. The bright pigment preferably has a specific surface area of 5.0 m2/g or less.
US10544307B2 Chlorinated copper phthalocyanine pigments
It is an object of the present technology to overcome the disadvantages of conventional chlorination of a copper phthalocyanine which produces copper phthalocyanine, wherein the number of chlorines is less than or equal to 4. The pigments described herein contain less chlorine than standard commercial grades of tetrachlorinated (or greater) copper phthalocyanine pigments while achieving similar color space, chromaticity, fastness properties, and color travel in automotive waterborne and solvent borne systems. The inventive pigments are more advantageous from a toxicity and environmental perspective, and allow the manufacturer to produce pigments in a safe and economical manner.
US10544305B2 Thermosetting resin composition, resin film for interlayer insulation, composite film, printed wiring board, and method for producing same
Provided is a thermosetting resin composition containing a polyimide compound (A) having a structural unit derived from a maleimide compound (a1) having at least two N-substituted maleimide groups and a structural unit derived from a diamine compound (a2); a modified polybutadiene (B); and an inorganic filler (C).
US10544300B2 Aqueous binder comprising reaction products of itaconic acid
An aqueous binder composition is provided for use in the formation of fiber insulation and non-woven mats that comprises a reaction product of one or more Liquid Polyol Monomers; itaconic acid, its salts or anhydride; and a C4 to C6 polyol selected from the group consisting of pentaerythritol, trimethylol propane, neopentyl glycol, and mixtures thereof. The molar ratio of the combined alcohols (Liquid Polyol Monomers and C4 to C6 polyols) to itaconic acid is at least 2:1, wherein the molar ratio of Liquid Polyol Monomers to C4 to C6 polyols is from about 1:1 to about 30:1.
US10544299B2 Vinyl-containing compounds with high heat distortion
A process for forming a thermosetting resin in a nitrogen atmosphere is provided. The process includes the steps of a) reacting a polycarboxylic acid and/or anhydride and a polyhydric alcohol to provide a hydroxyl-containing intermediate; b) reacting the hydroxyl-containing intermediate with a vinyl-containing organic acid or vinyl containing alkyl ester in the presence of an esterification catalyst, a polymerization inhibitor and an azeotropic agent; and c) reacting any residual vinyl-containing organic acid and residual esterification catalyst with an epoxide.
US10544294B2 Binder for injection moulding compositions
A binder for an injection moulding composition includes: from 35 to 54% by volume of a polymeric base, from 40 to 55% by volume of a mixture of waxes, and approximately 10% by volume of a surfactant, wherein the polymeric base contains copolymers of ethylene and methacrylic or acrylic acid, or copolymers of ethylene and vinyl acetate, or copolymers of ethylene including maleic anhydride or a mixture of these copolymers, as well as polyethylene, polypropylene and acrylic resin.
US10544293B2 Flame retardant resin composition and cable using the same
In a flame retardant resin composition containing a polyolefin resin, a silicone-based compound blended at a ratio of 1.5 parts by mass or more and 20 parts by mass or less relative to 100 parts by mass of the polyolefin resin, a fatty acid containing compound blended at a ratio of 5 parts by mass or more and 20 parts by mass or less relative to 100 parts by mass of the polyolefin resin, and an inorganic flame retardant blended at a ratio of 5 parts by mass or more and 40 parts by mass or less relative to 100 parts by mass of the polyolefin resin, the decomposition onset temperature of the inorganic flame retardant is lower than the decomposition onset temperature of the silicone-based compound.
US10544292B2 High-rigidity rubber composition
A rubber composition comprises at least one phenol/aldehyde resin based on at least one aromatic polyphenol comprising at least one aromatic ring bearing at least two hydroxyl functions in the meta position relative to one another, the two positions ortho to at least one of the hydroxyl functions being unsubstituted, and at least one aromatic polyaldehyde selected from 1,3-benzenedicarboxaldehyde, 1,4-benzenedicarboxaldehyde and mixtures of these compounds.
US10544290B2 Tire member manufacturing method and tire manufacturing method
A first tire member manufacturing method includes an operation in which master batch is made, and an operation in which the master batch and high-cis polybutadiene rubber are mixed. The operation in which the master batch is made includes an operation in which carbon-black-containing pre-coagulation rubber latex is coagulated to obtain a coagulum, an operation in which a compound according to Formula (I) is added to the water-containing coagulum, and an operation in which the compound according to Formula (I) is dispersed within the coagulum. In Formula (I), R1 and R2 each indicates a hydrogen atom, an alkyl group having 1 to 20 carbons, an alkenyl group having 1 to 20 carbons, or an alkynyl group having 1 to 20 carbons. R1 and R2 may be the same or different, M+ indicates sodium ion, potassium ion, or lithium ion.
US10544286B2 Polyamide moulding composition and moulded article made from this moulding composition
The present invention refers to a polyamide moulding composition consisting of the following components: a) 45 to 75% by weight of at least one partially crystalline polyamide consisting of at least one diamine and at least one aromatic dicarboxylic acid, whereupon the at least one diamine has 4 to 18 carbon atoms and is selected from a group of diamines consisting of linear aliphatic diamines, branched aliphatic diamines and cycloaliphatic diamines, b) 5 to 20% by weight of at least one fibrous reinforcing agent, c) 10 to 40% by weight of at least one non-sized filler which is different from the fibrous reinforcing agent in b), d) 0 to 10% by weight of a at least one additive, with the proviso that the component b) and c) add up to 25 to 45% by weight and the entirety of components a) to d) add up to 100% by weight. Moreover, the present invention refers to a moulded article producible from this moulding composition.
US10544285B2 Impact resistant cyclic phosphazenes
An impact-modified composition and a method of making an impact-modified composition are provided. In an embodiment, the method includes reacting a phosphazene material with an acrylamide material to form a functionalized phosphazene material; initiating a polymerization reaction on a reaction mixture comprising the functionalized phosphazene material and one or more monomers to form an impact-modified phosphazene material; and adding the an impact-modified phosphazene material to a polymeric material.
US10544284B2 Use of phosphorous-containing organic oxyimides as flame retardants and/or as stabilizers for plastics, flame-retardant and/or stabilized plastic compositions, method for the production thereof, moulded part, paint and coatings
The present invention relates to the use of phosphorous-containing organic oxyimides according to the general formula (I) as flame retardant for plastic materials, as radical generators in plastic materials and/or stabilisers for plastics. In addition, the present invention relates to a flame-retardant plastic material moulding compound in which the previously described phosphorous-containing organic oxyimides are integrated, and also to a method for the production of the previously mentioned plastic material composition. Furthermore, the present invention relates to a moulded article, a paint or a coating from the previously mentioned flame-retardant plastic material composition.
US10544277B2 Process for making gray expanded polystyrene
Gray expanded polystyrene achieving target molecular weight, bead size, bead distribution, and cell structure may be reproducibly prepared by suspension polymerization by introducing to the suspension polymerization an additive that is carbon black and/or graphite only after approximately 20 to 60 wt % of the styrene monomer has been converted to polystyrene. Introducing the additive at this point slows the polymerization rate, such as for an optimized period of time to allow for the droplet size to equilibrate to the desired target range. In one nonlimiting embodiment, the styrene polymerization rate has about 35 wt % to about 60 wt % styrene monomer remaining after about 3 hours from the beginning of polymerizing.
US10544275B2 Sizing agent coated carbon fiber bundle, method for manufacturing same, prepreg, and carbon fiber reinforced composite material
Provided are a sizing agent coated carbon fiber bundle that has excellent mechanical characteristics when used as a carbon fiber reinforced composite material, as well as excellent ease of handling; a method for manufacturing the same; and a prepreg and carbon fiber reinforced composite material of excellent mechanical characteristics, employing the fiber bundle. The carbon fiber bundle is coated with a sizing agent that includes a polyether aliphatic epoxy compound having two or more epoxy groups per molecule and/or a polyol aliphatic epoxy compound or a non-water-soluble compound having a glass transition temperature of −100-50° C., wherein the sizing agent coated carbon fiber bundle is characterized in that the flatness ratio (width/thickness) of the carbon fiber bundle cross section is 10-150, and a two edge part/center part sizing agent deposition ratio, obtained by dividing the carbon fiber bundle in the width direction along the fiber direction into three equal parts by mass, and computing the ratio from the ratio of the mass of the sizing agent to the mass of the carbon fiber bundle in the center part and in both end parts, is 1.05-1.5.
US10544274B2 Prepreg and fiber-reinforced composite material
A prepreg includes conductive fibers impregnated with a matrix resin, the prepreg having a conductive region where a conductive material is dispersed in the resin. In the present invention, a resin layer composed of at least the matrix resin preferably is present on one or both surfaces of a conductive fiber layer composed of at least the conductive fibers, and the conductive region is present at least in the resin layer. In addition, the above-described conductive region preferably is present continuously in the thickness direction. The conductive region preferably is a conductive region where the conductive material is dispersed in the matrix resin, and the resin in the conductive region preferably forms a continuous phase with the matrix resin in other regions. A volume resistivity of the conductive region preferably is 1/1,000 or less of that of other regions of the matrix resin.
US10544269B2 Thermoplastic nanocomposite particles, processes for their production, and their use in the fabrication of articles
A thermoplastic polymeric nanocomposite particle made by a method comprising: forming a polymer by polymerizing a reactive mixture comprising at least one of a monomer, an oligomer, or combinations thereof; said monomer and oligomer having two reactive functionalities, said polymerizing occurring in a medium also containing dispersed nanofiller particles possessing a length that is less than 0.5 microns in at least one principal axis direction, wherein said nanofiller particles comprise at least one of dispersed fine particulate material, fibrous material, discoidal material, or combinations of such materials, whereby said nanofiller particles become incorporated into the polymer.
US10544266B2 Composition for the production of polyimide film for flexible board of photoelectronic device
Disclosed is a polyimide precursor composition for the production of a flexible board of a photoelectronic device. The polyimide precursor composition includes a polyimide precursor derived from a diamine or acid dianhydride including a structure of Formula 1: wherein R1 to R8, m1, m2, and m3 are as defined in the specification. Also disclosed is a polyimide film produced from the polyimide precursor composition. The polyimide film is obtained by applying the precursor composition to a substrate and curing the composition. The polyimide film has high transparency and good heat resistance. In addition, the polyimide film exhibits good dimensional stability because the substrate does not undergo an increase in stress even during high-temperature heat treatment.
US10544265B2 Thermoset polymers having a triazine network obtained by reaction of cyanate esters with dicyanamide room temperature ionic liquids
The invention relates to the use of dicyanamide-containing ionic liquids which decrease the cure temperature of cyanate esters to form unique thermoset polymers having a triazine network. These thermoset polymers having the triazine network have an ionic character allowing for use in varied applications. The thermoset polymers described herein are useful in high temperature performance composites, and their high Tg makes them useful as a substitute for epoxies in the microelectronics industry. The thermoset polymers have good fracture toughness, excellent substrate adhesion, low shrinkage, and low moisture uptake.
US10544255B2 Epoxy resin composition, prepreg and laminate prepared therefrom
The present invention relates to an epoxy resin composition, comprising the following components: (A) an epoxy resin containing oxazolidinone structure having the structure of the formula (1), (B) an active ester curing agent, and (C) a curing accelerator. The epoxy composition, prepreg, laminate and printed circuit board prepared from such epoxy composition have the following features of low coefficient of thermal expansion, low dielectric loss factor Df less than or equal to 0.0084, low water absorption and excellent moisture and heat resistance.
US10544251B2 Tube using hydrogenated block copolymer
A tube including a hydrogenated block copolymer (a), wherein the hydrogenated block copolymer (a) includes, in a molecule, a polymer block mainly including a conjugated diene compound (C), a polymer block mainly including a conjugated diene compound (B), and a polymer block mainly including a vinyl aromatic compound (S).
US10544249B2 Method for preparing an aqueous polymer dispersion
Aqueous polymer dispersions and their use for producing shaped articles having improved heat resistance are described.
US10544244B2 Bridged biphenyl phenol transition metal complexes, production and use thereof
The present disclosure provides catalysts having a homoallylic bridge (and/or naphthyl moieties) located at a certain position on the catalysts which provides catalyst productivity values of 10,000 gPgcat−1hr−1 or greater and polyolefins, such as polyethylene, having an Mn of 100,000 g/mol or greater, Mw of 500,000 g/mol or greater, and an Mw/Mn value of about 1.5 to about 5. Catalyst systems including the catalysts, polymerization processes using the catalysts, and polymers made using the catalysts are also described.
US10544239B2 Organosilica materials and uses thereof
Organosilica materials, which are a polymer of at least one independent monomer of Formula [Z1OZ2OSiCH2]3 (I), wherein each Z1 and Z2 independently represent a hydrogen atom, a C1-C4 alkyl group or a bond to a silicon atom of another monomer and at least one other trivalent metal oxide monomer are provided herein. Methods of preparing and processes of using the organosilica materials, e.g., for catalysis etc., are also provided herein.
US10544237B2 Method of regulating hydrogen to a polymerization reactor
Disclosed is a method of reducing and/or regulating the level of hydrogen in a polymerization reactor comprising contacting a first feed comprising a first amount of hydrogen with a hydrogenation catalyst prior to entering a polymerization reactor to form a second feed; then contacting the second feed having a second amount of hydrogen with monomers and a polymerization catalyst in a polymerization reactor to form a polymer. The first and second feeds may reside in a feed line from one reactor to another, a monomer feed line to the reactor, or in a recycle line to and from the same reactor.
US10544229B2 Agonistic antibodies specifically binding CD40 and methods of use
The present invention relates to agonistic antibodies specifically binding human CD40, polynucleotides encoding the antibodies or antigen-binding fragments, and methods of making and using the foregoing.
US10544228B2 Nucleic acids encoding antibody polypeptides that antagonize CD40
Antibody polypeptides that specifically bind a novel epitope of human CD40 are provided. The antibody polypeptides do not exhibit CD40 agonist activity. The antibody polypeptides are useful in the treatment of diseases involving CD40 activation, such as autoimmune diseases. The antibody polypeptides may be domain antibodies (dAbs) comprising a single VL or VH domain. The half-life of the antibody polypeptides may be increased by modifying the antibody polypeptides to be dual specific reagents that can also bind human serum albumin (HSA).
US10544226B2 Antibody binding to FcRn for treating autoimmune diseases
The present disclosure relates to an isolated anti-FcRn antibody, which is an antibody binding to FcRn (stands for neonatal Fc receptor, also called FcRP, FcRB or Brambell receptor) that is a receptor with a high affinity for IgG or a fragment thereof, a method of preparing thereof, a composition for treating autoimmune disease, which comprises the antibody, and a method of treating and diagnosing autoimmune diseases using the antibody. The FcRn-specific antibody according to the present disclosure binds to FcRn non-competitively with IgG to reduce serum pathogenic auto-antibody levels, and thus can be used for the treatment of autoimmune diseases.
US10544223B2 Combination therapy with an anti-axl antibody-drug conjugate
The present disclosure relates to combination therapies for the treatment of pathological conditions, such as cancer. In particular, the present disclosure relates to combination therapies comprising treatment with an Antibody Drug Conjugate (ADC) and a secondary agent.
US10544216B2 P2X7 receptor antagonists and agonists
The present invention relates to biological materials against P2X7 and more in particular to polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the biological materials of the present invention inhibit the biological activity of the P2X7 receptor, such as activation by ATP.
US10544215B2 1-(Chloromethyl)-2,3-dihydro-1H-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment
The invention provides antibody-drug conjugates comprising an antibody conjugated to a 1-(chloromethyl)-2,3-dihydro-1H-benzo[e]indole (CBI) dimer drug moiety via a linker, and methods of using the antibody-drug conjugates.
US10544213B2 Compounds capable of antagonizing islet amyloid polypeptide (IAPP) induced beta-cell damage and impaired glucose tolerance
Described are molecules specifically binding to human islet amyloid polypeptide (hIAPP) also known as amylin, particularly human-derived antibodies as well as fragments, derivatives and variants thereof for antagonizing islet amyloid polypeptide (IAPP) induced β-cell damage and impaired glucose tolerance which are symptoms typically associated with diabetes mellitus type 2 (T2D).
US10544211B2 TNF binders
The present invention relates to amino acid sequences, compounds and polypeptides binding to tumor necrosis factor alpha (“TNF” or “TNF-alpha”). In particular, the present invention relates to improved heavy-chain immunoglobulin single variable domains (also referred to herein as “ISV's” or “ISVDs”) binding to tumor necrosis factor alpha, as well as to proteins, polypeptides and other constructs, compounds, molecules or chemical entities that comprise such ISVDs, collectively TNF binders. Other aspects, embodiments, features, uses and advantages of the invention will be clear to the skilled person based on the disclosure herein.
US10544209B2 Methods of replicating a large scale eculizumab production cell culture
Provided herein are methods of replicating a large scale eculizumab production cell culture in a small scale culture.
US10544208B2 Expression of a single chain antibody against Salmonella in Lactobacillus
The present disclosure relates to camel id antibodies that inhibit growth, and colonization of Salmonella serovars. The present disclosure also relates to a modified Lactobacillus as a delivery vehicle for controlling Salmonella in a host organism.
US10544206B2 Antibody capable of binding to norovirus, composite, detection device and method using the same
The present invention provides a novel antibody capable of binding to a norovirus. The present invention is an antibody that consists of an amino acid sequence, wherein said amino acid sequence consists of, in an N- to C-direction, the following structural domains: N-FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4-C wherein FR denotes a framework region amino acid sequence and CDR denotes a complementary determining region amino acid sequence; the CDR1 consists of any one of an amino acid sequences represented by SEQ ID NO: 1-SEQ ID NO: 6; the CDR2 consists of any one of an amino acid sequences represented by SEQ ID NO: 7-SEQ ID NO: 12; the CDR3 consists of any one of an amino acid sequences represented by SEQ ID NO: 13-SEQ ID NO: 17; and the antibody is capable of binding to a norovirus.
US10544205B2 Anti-Pre-S1 HBV antibodies
Provided are human antibodies that specifically bind to HBV Pre-S1 domain ligand and inhibit HBV or HDV infection, antibodies binding to a set of amino acid residues that are critical for viral receptor engagement, and uses of these antibodies to prevent, or treat or diagnose HBV or HDV infection.
US10544200B2 Glycoprotein hormone long-acting superagonists
This invention provides long-acting, superactive analogs of glycoprotein hormones demonstrating enhanced bioactivity both in vitro and in vivo as compared to wild type counterparts. The analogs are particularly useful for treating subjects showing low receptor expression or poor receptor responsiveness, and for the treatment of any condition associated with glycoprotein hormone activity.
US10544198B2 Methods of accelerating or improving wound healing using IL-22 FC fusion proteins
The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
US10544197B2 FGF-23 epitope peptide for improving resistance to breakage and eggshell strength
Described herein are FGF-23 epitope peptides, methods of producing antibodies in laying hens by injecting the peptides, and methods of improving resistance to eggshell breakage and/or increasing eggshell strength by administering an FGF-23 epitope peptide to a laying hen.
US10544191B2 Methods and compositions for ribosomal synthesis of macrocyclic peptides
Methods and compositions are provided for generating macrocyclic peptides from genetically encoded, ribosomally produced polypeptide precursors. Also provided are nucleic acid molecules, polypeptides, and methods for generating combinatorial libraries of macrocyclic peptides. These methods can be used to produce vast libraries of conformationally constrained peptide ligands as well as facilitate the functional screening of these libraries to identify compound(s) with desired activity properties.
US10544189B2 Process for the preparation of (2S)-N-((S)-1-((S)-4-methyl-1-((R)-2-methyl oxiran-2-yl)-1-oxopentan-2-ylcarbamoyl)-2-phenylethyl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)-4-methylpentanamide
The present invention relates to process for the preparation of (2S)-N-((S)-1-((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-ylcarbamoyl)-2-phenyethyl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)-4- methylpentanamide represented by the following structural formula-1.
US10544186B2 Process for the synthesis of amide bonds with the aid of novel catalysts
The invention relates to a process for the production of amide bonds, in particular peptide bonds, with the aid of novel amide linking reagents containing an anion of the formula (I), to the novel reagents, and to the preparation thereof.
US10544185B2 Deuterated chenodeoxycholic acid derivative and pharmaceutical composition comprising compound thereof
Disclosed are deuterated chenodeoxycholic acid derivatives and pharmaceutical compositions containing the deuterated chenodeoxycholic acid derivatives. In particular, disclosed is a deuterated chenodeoxycholic acid derivative of formula (I), or a crystal form, pharmaceutically acceptable salt, hydrate or solvate thereof, and a pharmaceutical composition containing the same. The deuterated chenodeoxycholic acid derivatives of formula (I) can be used to treat and/or prevent diseases related to the farnesoid X receptor (FXR) and/or G-protein coupled bile acid receptor, such as nonalcoholic steatohepatitis, nonalcoholic fatty liver diseases, gallstones, primary biliary cirrhosis, and cirrhosis.
US10544183B2 Uridine nucleoside derivatives, compositions and methods of use
This disclosure relates to uridine nucleoside derivatives, compositions comprising therapeutically effective amounts of those nucleoside derivatives and methods of using those nucleoside derivatives or compositions in treating disorders that are responsive to ligands, such as agonists, of P2Y6 receptor, e.g., neuronal disorders, including neurodegenerative disorders (e.g., Alzheimer's disease, Parkinson's disease) and traumatic CNS injury, pain, Down Syndrome (DS), glaucoma and inflammatory conditions.
US10544182B2 Synthesis of desosamines
The present invention provides desosamine and mycaminose analogs and nitro sugars and methods for their preparation. The invention also provides methods of cyclizing a compound of Formula (A′) with glyoxal to give a nitro sugar of Formula (B). Methods for the preparation of compound of Formula (D′) are provided comprising cyclization of a nitro alcohol to give a nitro sugar and reduction and alkylation of the nitro sugar to give a desosamine, mycaminose, or an analog thereof.
US10544177B2 Chiral dihydrobenzooxaphosphole ligands and synthesis thereof
This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.
US10544176B2 Prodrugs of prostate specific membrane antigen (PSMA) inhibitor
Methods and compounds are disclosed for treating a disease or condition by inhibiting PSMA (Prostate Specific Membrane Antigen) using prodrugs of 2-PMPA.
US10544172B2 Phosphate composition
A process for the preparation of a composition comprising amine-containing phosphate glycerides including: phosphorylating a solution which comprises mixed glycerides that contain fatty acid portions and an amine under conditions which are substantially water-free and under which said phosphorous pentoxide reacts with reactive constituents in said solution to form said amine-containing phosphate glycerides and a lubricating composition comprising a lubricant, the aforesaid composition in an amount which improves the properties of the lubricating composition, and optionally one or more other constituents which improve the properties of the lubricating composition.
US10544169B2 Process for organochlorosilane production in the fluidized bed process
A process for producing organochlorosilanes in a fluidized bed reaction comprises reacting haloorganic reaction gas with a catalytic composition comprising silicon, copper catalysts and promoters, in a fluidized bed reactor, wherein the hydraulic diameter of the fluidized bed reactor dhyd, the superficial gas velocity in the fluidized bed reactor uL and the particle Sauter diameter of the catalytic composition d32 are selected such that, in a Cartesian coordination system in which Ar is plotted against Re, points on the surface are formed wherein the surface is limited by equations 1 and 2 Ar=2·10−5·Re2+0.08*Re−120  Equation 1: Ar=2·10−5·Re2−1.07*Re+14100  Equation 2: wherein the lower limit Ar=0.5 and the upper limit Ar=3000. The invention also relates to a method for selecting reaction parameters for producing organochlorosilanes.
US10544166B2 Compound and color conversion film comprising same
The present specification relates to a novel compound, and a color conversion film, a backlight unit and a display apparatus including the same.
US10544160B2 Production method of thienopyrimidine derivative
The present invention provides a production method of a thienopyrimidine derivative or a salt thereof which has a gonadotropin releasing hormone (GnRH) antagonistic action with high quality in high yield. The present invention provides a method of producing a thienopyrimidine derivative, which comprises reacting 6-(4-aminophenyl)-1-(2,6-difluorobenzyl)-5-dimethylaminomethyl-3-(6-methoxypyridazin-3-yl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione or salt thereof, 1,1′-carbonyldiimidazole or a salt thereof and methoxyamine or a salt thereof, and the like.
US10544159B2 Artemisinin derivatives, methods for their preparation and their use as antimalarial agents
Derivatives of the antimalarial agent artemisinin, compositions comprising the derivatives, methods for preparing the derivatives, and their uses in pharmaceutical compositions intended for the treatment of parasitic infections are provided. Methods are provided for the production of artemisinin derivatives via functionalization of positions C7 and C6a, and optionally, in conjunction with modifications at positions C10 and C9, via chemoenzymatic methods. Recombinant cytochrome P450 polypeptides are also provided for use in the methods. The artemisinin derivatives can be used for the treatment of malaria and other parasitic infections, alone or in combination with other antiparasitic drugs.
US10544158B1 Process for producing polycyclic polyether polyols
Processes are described for producing a polycyclic polyether polyol having a hydroxyl functionality of 1.5 to 6 and a number average molecular weight of 200 to 12,000 Da. The processes comprise alkoxylating a polyol starter comprising predominantly a polycyclic polyol with an alkylene oxide in the presence of a DMC catalyst.
US10544157B2 Process for preparation of Darunavir
The present invention provides a process for the preparation of darunavir or solvates or a pharmaceutically acceptable salt thereof substantially free of bisfuranyl impurities, particularly darunavir propionate solvate. The present invention also provides a process for preparation amorphous darunavir using the darunavir propionate solvate.
US10544153B2 Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxycodone, prodrugs, methods of making and use thereof
The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxycodone (4,5-α-epoxy-14-hydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxycodone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxycodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.
US10544151B2 Compounds and uses thereof
The present invention provides novel compounds of any one of Formulae (I)-(IV), and pharmaceutical compositions thereof. Also provided are particles (e.g., nanoparticles) comprising compounds of any one of Formulae (I)-(IV) and pharmaceutical compositions thereof that are mucus penetrating. The invention also provides methods and kits for using the inventive compounds, and pharmaceutical compositions thereof, for treating and/or preventing diseases associated with abnormal or pathological angiogenesis and/or aberrant signaling of a growth factor signaling pathway (e.g., vascular endothelial growth factor (VEGF), such as proliferative diseases (e.g., cancers, benign neoplasms, inflammatory diseases, autoimmune diseases) and ocular diseases (e.g., macular degeneration, glaucoma, diabetic retinopathy, retinoblastoma, edema, uveitis, dry eye, blepharitis, and post-surgical inflammation) in a subject in need thereof.
US10544144B2 Fused pyrimidine piperidine cyclic derivative, preparation process and use thereof
The present invention relates to the fused pyrimidine piperidine cyclic derivative represented by the following formula (I) and a pharmaceutically acceptable salt thereof and a process for preparing the same, wherein R1, R2, R3, R4, R5, X, Y and Z are defined as in the description. The present invention further provides use of said fused pyrimidine piperidine cyclic derivative in manufacture of a medicament for preventing or treating FGFR kinase mediated disease such as cancer.
US10544143B2 4-azaindole compounds
Disclosed are compounds of Formula (I) N-oxides, or salts thereof, wherein G, A, R1, R5, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.
US10544140B2 Pharmaceutical composition containing, as active ingredient, 7-azaindolin-2-one derivative or pharmaceutically acceptable salt thereof
7-azaindolin-2-one derivatives of Formula 1 or pharmaceutically acceptable salts thereof, a pharmaceutical composition comprising them for preventing or treating a cancer, and a method for preparing them.
US10544139B2 Treatment of osteoarthritis
Provided are compositions and methods for treating osteoarthritis including intra-articular administration of a compound of Formula (I) including amorphous and polymorph forms thereof.
US10544138B2 Tricyclic kinase inhibitors of MELK and methods of use
Provided herein are tricyclic small molecule inhibitors of maternal embryonic leucine zipper kinase (MELK). The compounds are useful for treating cancer and other conditions or diseases associated with aberrant MELK expression. Also provided herein are pharmaceutical compositions comprising a tricyclic compound of the invention and a pharmaceutically acceptable carrier. The invention also provides methods of treating cancers associated with over-expression of MELK.
US10544137B2 PI3K inhibitor, and pharmaceutically acceptable salt, polycrystalline form, and application thereof
The present invention relates to a PI3K inhibitor, and a pharmaceutically acceptable salt, polycrystalline form, and application thereof. The invention specifically provides a polycrystalline form of 4-chloro-5-(6-(1-(methylsulfonyl)cyclopropyl)-2-morpholinopyrimidin-4-yl)pyridin-2-amine, a pharmaceutically acceptable salt thereof, or a polycrystalline form of the salt. The invention further discloses a pharmaceutical composition comprising the inhibitor and an application of the pharmaceutical composition.
US10544136B2 Modulators of sphingosine phosphate receptors
Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided.
US10544129B2 Crystalline forms of AP26113, and preparation method thereof
The present disclosure relates to two novel crystalline forms of AP26113 and processes for preparation thereof. The crystalline form CS1 and crystalline form CS2 of the present disclosure have advantages in solubility and stability, are suitable for development, and provide a better choice for preparation of pharmaceutical compositions containing AP26113, which is of great significance for drug development.
US10544124B2 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides
The present invention relates to compounds of the general formula (I) in which Q, V, T, W, X, Y and A have the meanings given in the description—and to their use for controlling animal pests.
US10544121B2 Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling
Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.
US10544120B2 Biaryl kinase inhibitors
The present disclosure is directed to biaryl compounds of formula (I) which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds and their use for treating e.g. pain, Alzheimer's disease, Parkinson's disease and schizophrenia.
US10544113B2 Thiazolidinone compounds and use thereof
A pharmaceutical composition containing a compound of Formula (I) for treating an opioid receptor-associated condition. Also disclosed is a method for treating an opioid receptor-associated condition using such a compound. Further disclosed are two sets of thiazolidinone compounds of formula (I): (i) compounds each having an enantiomeric excess greater than 90% and (ii) compounds each being substituted with deuterium.
US10544111B2 Heterocyclic compound
Provided is a heterocyclic compound having a superior RBP4-lowering action and useful as a medicament for the prophylaxis or treatment of a disease or symptom mediated by an increase in RBP4 or retinol supplied by RBP4.A compound represented by the formula (I): wherein each symbol is as defined in the Description, or a salt thereof has a superior RBP4-lowering action, and is useful as a medicament for the prophylaxis or treatment of a disease or symptom mediated by an increase in RBP4 or retinol supplied by RBP4.
US10544108B2 Hydrazide containing nuclear transport modulators and uses thereof
The invention generally relates to nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by structural formula I: or a pharmaceutically acceptable salt thereof, wherein the values and alternative values for the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity.
US10544106B2 Certain chemical entities, compositions, and methods
Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.
US10544105B2 Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage
Provided herein are dUTPase inhibitors of Formula (I), compositions comprising such compounds and methods of using such compounds and compositions
US10544101B2 Process for the preparation of butorphanol tartrate
The present invention relates to an improved process for the preparation of Butorphanol tartrate of formula (I),
US10544094B2 Beta-mercaptoethanol synthesis
A process includes reacting, in a reactor having a fixed bed containing a solid catalyst which contains a heterogeneous ion exchange resin, hydrogen sulfide and ethylene oxide in the presence of the solid catalyst to yield a reaction product which contains beta-mercaptoethanol. A reactor system includes the reactor, an ethylene oxide stream, a hydrogen sulfide stream, a fixed bed containing the solid catalyst placed in the reactor, and an effluent stream containing the reaction product. During steady state operation of the reactor in the process and the reactor system, the hydrogen sulfide and the ethylene oxide are present in a mole ratio in a range of about 9:1 to about 20:1.
US10544092B2 Malononitrile oxime ether compound and use thereof
Disclosed is a malononitrile oxime ether compound having a novel structure as shown in the general formula I. Respective substituents in the general formula I as defined in the specification. The compound of the general formula I exhibits an excellent microbicidal activity, and can effectively prevent and treat plant diseases caused by bacteria and fungi. Also provided is a use of the compound of the general formula I as a microbicide in the agricultural and other fields.
US10544089B2 Innovative preparation and crystallization of iosimenol
The present invention generally relates to a process of preparing iosimenol and a process of preparing a crystal of iosimenol, as well as a crystal of iosimenol prepared by these processes.
US10544088B2 Pharmaceutically acceptable salts of fatty acids
The present disclosure provides pharmaceutically acceptable stable salt forms of 15-lipoxygenase products, such as 15-HETrE lysine salt, compositions comprising same and methods of making and using same.
US10544082B2 Method to produce acrylic acid with acetaldehyde as the main by-product
Described herein are solid acid catalysts and the methods for catalytically preparing α,β-unsaturated carboxylic acids and/or esters thereof. In one aspect, a zeolite catalyst may be used. The catalyst may, in certain embodiments, be modified to improve the selectivity and/or conversion of a reaction. For instance, a catalyst may be modified by ion exchange to achieve a desirable acidity profile in order to achieve high level of conversion of reactants and selectivity for desirable products of the catalytic reaction. In another aspect, a variety of feed stocks (e.g., starting compositions) may be used including an α-hydroxycarboxylic acid, an α-hydroxycarboxylic acid ester, a β-hydroxycarboxylic acid, a β-hydroxycarboxylic acid ester, cyclic esters thereof (e.g., lactide), and combinations thereof.
US10544081B2 Process for preparing mandelic aromatic compounds and aromatic aldehyde compounds
A process for preparing an aromatic compound or compounds where at least one mandelic group —CHOH—COOH is described, comprising a reaction for condensation of at least one aromatic compound with glyoxylic acid or derivatives thereof, wherein said condensation reaction is carried out substantially in the absence of any acid or any base added to the reaction medium. The condensation reaction is followed by an oxidation reaction in order to obtain aromatic aldehyde.
US10544079B2 Process for the direct conversion of diisobutene to a carboxylic acid
Process for the direct conversion of diisobutene to a carboxylic acid.
US10544078B2 Polyethylene terephthalate depolymerization
The present invention relates to the depolymerization of polymers and the recovery of the starting materials used for the production of the polymer. The present invention also relates to the depolymerization of polyethylene terephthalate (PET) and the recovery of terephthalic acid and ethylene glycol.
US10544075B2 Derivatives of sobetirome
Disclosed are halo substituted derivative compounds of sobetirome with improved pharmacological characteristics relative to sobetirome, pharmaceutical compositions that include those compounds and methods of treating diseases such as neurodegenerative disorders using those pharmaceutical compositions.
US10544074B2 Low-viscosity solutions of alkaline-earth metal alkoxides in aprotic solvents, method for the production of same and use for the production of Ziegler-Natta catalysts
One or more concentrated low-viscosity solutions of alkaline earth alkoxide compounds M(OCH2R6)2-a-b(OR7)a[O(CHR8)nOR9]b in mixture with a metal alkyl compound M(R10R11) in an aprotic solvent and related methods are disclosed herein.
US10544070B2 Ethylene oligomerization process
Disclosed herein is a process for forming an oligomer product comprising (a) introducing into a reaction zone (i) ethylene; (ii) a heteroatomic ligand metal salt complex comprising a heteroatomic ligand complexed to a first metal salt; (iii) a second metal salt wherein an equivalent molar ratio of the second metal salt to the heteroatomic ligand of the heteroatomic ligand metal salt complex is at least 0.5:1 and where the second metal salt is an iron salt, a cobalt salt, or any combination thereof; (iv) an organoaluminum compound; and (b) forming an oligomer product. Also disclosed herein is a process comprising (a) introducing into a reaction zone (i) ethylene; (ii) a heteroatomic ligand; (iii) a metal salt where an equivalent molar ratio of the metal salt to the heteroatomic ligand is at least 1.5:1; (iv) an organoaluminum compound; and (b) forming an oligomer product.
US10544066B2 Microencapsulated nitrification inhibitor compositions
The present disclosure relates to an improved nitrification inhibitor composition and its use in agricultural applications.
US10544065B2 Organic-inorganic polymeric water-retaining fertilizer and preparation method of the same
Provided is an organic-inorganic polymeric water-retaining fertilizer, which is a co-polymer made by fusion and co-polymerization of an organic water-retaining monomer and an inorganic nutrient under action of a catalyst, a biological enzyme and a modifying agent. The co-polymer is of a three-dimensional mesh-like hydrophilic group structure. In a method for preparing the organic-inorganic polymeric water-retaining fertilizer, after obtaining a neutralized pre-polymer from the organic monomer with the catalyst, an initiator and a cross-linking agent are added; the inorganic nutrient and a metasilicate are added simultaneously, a solution is formed by stirring sufficiently; the biological enzyme is added for catalysis; a co-polymer is obtained after fusion and co-polymerization; and granulation and drying are carried out. Preferably, the catalyst is an inorganic alkaline solution. Preferably, the catalyst is selected from the group consisting of a sodium hydroxide solution, a potassium hydroxide solution, an ammonia water and a calcium hydroxide solution.
US10544060B2 Composition for metakaolin construction material, related method for manufacturing said composition, and use for producing construction elements
Disclosed is a construction material composition including a matrix predominantly containing an aluminum silicate compound, such as a metakaolin, and an alkaline activation solution. The composition is contains less than 10 wt. % cement or clinker and in that the metakaolin is a metakaolin obtained via flash calcination. The reaction between the components is carried out at a temperature less than 30° C. The method for manufacturing the construction material includes mixing the composition with various elements such as granulates, plant fibers, unfired clay, and expanding agents. It is particularly of use in producing floor, wall, or roof coating elements, prefabricated construction elements, or insulation, adhesive, or inorganic sealant modules.
US10544058B1 High thermal expansion glass composites and uses thereof
The present invention relates to glass composites, including filled glass composites and uses thereof. In particular examples, the composites provide improved thermal expansion characteristics. Also described are methods of forming such composites, such as by adding a particle filler to a glass mixture.
US10544053B2 Systems for petroleum wastewater treatment including removable coalescer components and related methods
Apparatus for removing suspended impurities from a liquid (e.g., wastewater), methods of use, and systems including such apparatus. In an embodiment, an apparatus may include a vessel defining a chamber for receiving gas induced liquid influent through an inlet, the influent including suspended impurities. A riser tube may be provided within the vessel, in fluid communication with the inlet so that liquid influent introduced into the vessel through the inlet is introduced into the riser tube. One or more coalescing members may be disposed within the riser tube. The coalescing members may be sufficiently small to be easily removable by hand, without requiring a crane. The coalescing members may be freely disposed within the riser tube, rotatable within the flow of the liquid influent, aiding the coalescing members in exhibiting some degree of “self-cleaning”, so as to be less prone to fouling and clogging.
US10544050B2 Positive electrode active material for sodium-ion batteries
A positive electrode active material for a sodium-ion secondary battery contains a compound of formula NaxMn1-y-zMyM′zO2 or its hydrate. A cathode can contain the active material and rechargeable sodium-ion battery can contain such a cathode.
US10544049B2 Process for preparing a porous inorganic powder
The present invention is directed to a process for preparing an inorganic aerogel, the process comprising the steps of providing a composition (I) suitable to form an inorganic gel with a gelation time tG, spraying the composition (I) into supercritical carbon dioxide at a spraying time tS to obtain gel particles, and drying the gel particles obtained in step (ii) by supercritical liquid extraction, wherein the ratio tS:tG is in the range of from 0.2 to 0.99. The present invention further is directed to the inorganic aerogel as such as well as the use of the inorganic aerogel according to the invention in particular for medical and pharmaceutical applications or for thermal insulation.
US10544045B2 Ozone generation system and method for operating same
In an ozone generating system in which an intermittent operation is performed, in which an ozone generating operation period in which ozone is generated by discharging gas which contains oxygen in a discharge space of an ozone generating apparatus and an ozone generating operation standby period in which gas is sealed in an ozone generating apparatus and discharge is stopped so as not to generate ozone are performed repeatedly, an absorbent which absorbs at least one of nitric acid and nitrogen oxide is provided in an ozone generating apparatus other than the discharge space.
US10544043B2 Multi-chamber hypochlorous acid dispenser
The invention provides a skin disinfectant for treating skin with eczema, preventing bacterial proliferation, and removing biofilm. Compositions of the invention include hypochlorous acid, acetic acid, water, and one or more additives or excipients. The formulation process removes metal ions, reduces ionic strength, controls pH, and reduces exposure to air, thus improving stability and lengthening shelf-life.
US10544037B2 Integrated semiconductor device and manufacturing method
The present disclosure relates to an integrated semiconductor device, comprising a semiconductor substrate; a cavity formed into the semiconductor substrate; a sensor portion of the semiconductor substrate deflectably suspended in the cavity at one side of the cavity via a suspension portion of the semiconductor substrate interconnecting the semiconductor substrate and the sensor portion thereof, wherein an extension of the suspension portion along the side of the cavity is smaller than an extension of said side of the cavity.
US10544036B2 Microfluidic devices and methods for the extrusion of tubular structures
Methods and devices are disclosed for the controlled formation of structures, including tubular structures, using microfluidic devices. In one embodiment, a microfluidic device includes three or more microfluidic arrays that are provided in a stacking configuration, with an inner streaming layer and an outer streaming layer for flowing a streaming fluid, and at least one intermediate matrix layer for flowing a matrix fluid. Fluid flow in each layer is directed from a peripheral region towards, and distributed around, a common central outlet. Guided by the streaming fluid, a sheath of matrix solution is formed, which may be solidified to form a tubular material. Some embodiments allow for the controlled and continuous extrusion of tubular structures with tailored heterogeneities and/or predictable mechanical and chemical properties. Devices and methods are also provided for the on- and off-chip fixation and optional perfusion of tubular structures.
US10544034B1 Nickel lanthanide alloys for mems packaging applications
A semiconductor package including a semiconductor die and at least one bondline positioned on the semiconductor die, the at least one bondline comprising a nickel lanthanide alloy diffusion barrier layer abutting a gold layer.
US10544030B2 Multi-compartment pitcher with selectable dispensing port
The disclosed device is a multi-compartment container. Each compartment is capable of holding a different liquid. The user actuates a valve to dispense the liquid of his or her choice.The multi-compartment pitcher with selectable dispensing port eliminates spillage from the top, and eliminates fumbling over multiple and various drinks or liquids. The device compartmentalizes multiple drinks or liquids within a single container, while easily dispersing the drink or liquid from the designated bottom port.
US10544028B2 Beverage dispensing container, apparatus, system and method
The present invention is directed to a beverage dispensing system including at least one beverage dispensing container, a computing device and a base unit upon or within which, in use, the at least one container is positioned. The at least one container includes a reservoir of beverage, a communication element for storing data indicative of contents of the beverage dispensing container, a manually actuatable dispensing valve selectively controlling flow of beverage from the reservoir to a container outlet, and pressurizing means for pressurizing beverage against the dispensing valve such that when the dispensing valve is opened beverage flows from the reservoir and out the container outlet. The base unit includes at least one base-container transceiver for wirelessly reading data from and writing data to the communication element, at least one base-device transceiver for wirelessly communicating with the computing device, and a control unit controlling communication of data from the computing device to the communication element and vice-versa.
US10544027B2 Beverage dispensing system with recirculation loop heat exchange assembly
The present application thus provides a beverage dispensing system for combining a macro-ingredient flow and a carbonated water flow. The beverage dispensing system may include a nozzle, a carbonated water source in communication with the nozzle via a carbonated water conduit and a carbonated water recirculation conduit, a macro-ingredient source in communication with the nozzle via a macro-ingredient conduit, and a macro-ingredient pump and an air chamber in communication with the macro-ingredient conduit. The carbonated water recirculation conduit is in communication with the air chamber for heat exchange therewith.
US10544025B1 Appliance for opening screw and twist type containers
An appliance for opening screw and twist type containers for prescription medicine bottles, water bottles, sports drinks, and jars of nearly all sizes. The appliance has a thermoplastic body with an integrally molded low profile unidirectional gripping blade being positioned on the center line of the appliance. The appliance has an optimized offset from center line loading ramp and reaction plane resulting in a highly efficient opener with an asymmetrical split V type geometry. The appliance provides the optimal leverage, retention, and gripping force required to greatly ease in the removal of screw or twist type container lids ranging in size from ½″ to 4½″ in diameter. This under cabinet mounted appliance provides unprecedented ease in opening even the most difficult twist type container or jar, which is very beneficial for the aging, as well as the young, and those with arthritic conditions or other hand related problems.
US10544023B2 Guide-roll arrangement for guiding relative movement of members of a lift-truck and a lift-truck comprising a guide-roll arrangement
A guide-roll arrangement for guiding movement of a first member relative a second member of a lift-truck, comprising a roll pin having opposing first and second ends, wherein the first end comprises a recess; and a roll supported on the roll pin; and a sliding element arranged in the recess, said sliding element comprising opposing contact and sliding surfaces, wherein a support piece is arranged in the recess and comprising a contact surface for supporting the sliding element, wherein the contact surface of the sliding element is supported on the contact surface of the support piece and wherein one of the contact surfaces of the support piece and the sliding element is concave and the other is convex.
US10544022B2 Handle position sensing systems and methods for a material handling vehicle
Provided are systems and methods for monitoring the position of a handle of a material handling vehicle comprising a handle, a first sensor positioned along the material handling vehicle, a second sensor positioned along the handle, and a controller configured to retrieve first positional information from the first sensor, retrieve second positional information from the second sensor, and compare the first positional information with the second positional information. The controller can adjust the operation of at least one of a lift motor and a drive motor of the material handling vehicle based on the comparison of the first positional information with the second positional information.
US10544017B2 Winch with one-way reverse tensioner
A winch is described that includes a drum, a motor and transmission, and a tensioner. The motor and transmission apply torque to the drum, thereby enabling the drum to draw in and let out a line. The tensioner is positioned adjacent to the drum, such that when the line passes between the tensioner and drum, the line is in frictional contact with the tensioner and drum. The tensioner rotates with a linear speed exceeding a linear speed of the drum as the line is let out from the drum, and rotates freely as the line is drawn onto the drum. Methods for making and using the winch are also described.
US10544015B1 Device and method for lifting an object from a deck of a vessel subject to movements
Described is a device for lifting an elongated object from a deck of a vessel subject to movements in a heave direction. The device comprises rigid supports provided on the deck of the vessel for supporting the object at a first height relative to the deck, and retractable supports provided on the deck of the vessel for supporting the object at a second height relative to the deck, which second height is larger than the first height. A lifting crane is configured to take up the object from the retractable supports at the second height. An actuator system is configured to lower the retractable supports in the heave direction to a third height relative to the deck at the instant in time the object is lifted from the retractable supports, the third height being smaller than the second height. A method using the device is also described.
US10544014B2 Method for hoisting and transporting assemblies in underground nuclear power plant
A method for hoisting and transporting assemblies in an underground nuclear power plant, the method including: 1) pouring concrete onto a reactor cavern to form a rock anchor beam; hoisting a circular bridge crane to the reactor cavern through a hoist shaft on a top of the reactor cavern; mounting the circular bridge crane on the rock anchor beam by using a truck crane; 2) installing a containment cylinder and a track beam of a polar crane in the reactor cavern using the circular bridge crane; hoisting a gantry crane on one end of a polar crane girder and sending the polar crane girder to the reactor cavern; hoisting the other end of the polar crane girder using the circular bridge crane; allowing the polar crane girder to be horizontal; and mounting the polar crane girder on the track beam.
US10544011B2 Hoisting frame for overweight lifting
Provided are weight distribution hoisting brackets and methods of using such brackets that offset a lifting position to an upper lifting mechanism off a center line of a heavy load to be lifted enabling sharing of the weight of a load to be lifted between at least two lifting mechanisms such as cranes such that lifting mechanisms may be employed that have a lower lifting weight capacity than the weight of the load.
US10544003B2 Brake assembly for a tape dispenser
A tape dispenser housing wound adhesive tape includes a brake spoke tapering (i.e., narrowing) from a distal radial end to a proximal radial end relative to a tape rotational axis, wherein the brake spoke effectuates the braking of wound adhesive tape on a hub by contacting the wound adhesive tape, the hub, or both simultaneously.
US10544002B2 Brake assembly for a tape dispenser
A tape dispenser housing wound adhesive tape includes a brake spoke tapering (i.e., narrowing) from a distal radial end to a proximal radial end relative to a tape rotational axis, wherein the brake spoke effectuates the braking of wound adhesive tape on a hub by contacting the wound adhesive tape, the hub, or both simultaneously.
US10543997B2 Sheet feeding apparatus and image forming apparatus
A sheet feeding apparatus includes an abutment part having an abutment area against which a leading edge of a sheet abuts and a moving part to move the abutment part between first and second positions. The moving part includes a link member having an engage portion to engage with a positioning portion, the link member being joined with the abutment part, and an urging member to urge the link member such that the abutment part moves toward the second position. The abutment part is retained at the first position against an urging force of the urging member in a case where the positioning portion is engaged with the engage portion of the link member.
US10543990B2 Automatic front and rear lift self-propelled agricultural conveyor
An agricultural conveyor is provided. The agricultural conveyor includes a self-propelled chassis. A conveyor is carried by the self-propelled chassis. The front end of the conveyor is configured to be raised and lowered automatically.
US10543987B2 Conveyor belt and module with skewed air-flow passages
A conveyor belt and a belt module having airflow passages that direct air exiting the module in different directions to agitate conveyed products. The airflow passages of injection-molded belt modules are formed with no undercut regions to accommodate the clean parting of the mold halves.
US10543980B1 Roll-off tub style container
A roll-off tub style container which is leak-proof to prevent liquids in the container from draining onto the ground or roadways. In one embodiment of the invention, the floor of the container has an upwardly and rearwardly extending inclined portion at the rearward end thereof to prevent liquid in the container from coming into contact with the tail gate of the container. In another embodiment of the invention, the rearward end of the container is elevated during transport to prevent liquid in the container from coming into contact with the tail gate. In yet another embodiment of the container, the floor of the container is inclined upwardly and rearwardly from the forward end thereof to the rearward end thereof. A liquid collection tank may be positioned beneath the floor of the container which has an inlet in fluid communication with the interior of the container and a discharge outlet provided thereon to permit liquid in the tank to be selectively drained therefrom.
US10543979B2 Capsules, apparatus and methods for preparing a beverage
A beverage preparation capsule containing a beverage preparation ingredient, having a body with side walls formed from one or more substantially air- and liquid-impermeable sheet materials defining a chamber containing a beverage preparation ingredient and further defining an outlet channel having an upstream end in fluid communication with the chamber for escape of beverage from the chamber. At least a region of the outlet channel is filled by a filtration material for filtering the beverage escaping from the chamber. Also provided is a clamp assembly for preparing a beverage from such a capsule, the clamp assembly comprising two or more clamp members, wherein an inner wall of at least one of the clamp members comprises a concave base surface for receiving the capsule and one or more pressure pads projecting from the concave base surface for selectively constricting a region of the capsule. Also provided are a beverage preparation apparatus and system comprising the clamp assembly, and a method of preparing a beverage from the apparatus.
US10543978B1 Rapidly cooling food and drinks
Systems and methods have demonstrated the capability of rapidly cooling the contents of pods containing the ingredients for food and drinks.
US10543976B2 Packaging for light bulbs
A protective sleeve, adapted to receive at least a first light bulb, includes parallel first and second panels, wherein at least the second panel includes a plurality of apertures. The package also includes a pair of sidewalls generally perpendicular to and connecting the panels, wherein the first panel, second panel and sidewalls together define an interior space. A second sleeve is adapted to receive at least a second light bulb. When the sleeve and the second sleeve are received together into the outer shell in an inverted orientation relative to each other sleeve, the respective second panels of the sleeve are adjacent each other, and the bulb portion of each of first and second light bulbs positioned with the sleeve intrudes into an interior space of the adjacent sleeve through at least one of the plurality of apertures of each of the sleeves.
US10543974B2 Pressure control system
A pressure control system provided for maintaining a constant predetermined excess pressure in a fluid dispensing container comprises a high-pressure plastic vessel having an inner chamber, and a pressure control device having a valve and mounted on the open end of the high-pressure vessel, whereas a passageway is provided from the inner chamber to the outside, which is controlled by the valve. A piston with a protruding stem is provided in a guide member, whereas between the guide member and the piston a chamber with a gas with a reference pressure smaller than the high pressure is enclosed, and the high pressure vessel is closed by a closure with a central bore of smaller diameter than the diameter of the stem, and the piston end remote from the protruding stem is pressurized by the fluid in the fluid dispensing container.
US10543970B2 Flexible packaging structure with a built-in opening and reclose feature
A flexible packaging laminate is formed to have a built-in opening and reclose feature by forming the laminate as a two-part structure having an outer structure joined in face-to-face relation with an inner structure. Score lines are formed in both structures to enable an opening to be formed through the laminate by lifting an opening portion (e.g., a flap or the like) of the two structures out of the plane of the laminate. The score line through the outer structure defines a larger opening than the score line through the inner structure, such that a marginal region of the outer structure extends beyond the edge of the opening portion of the inner structure. A pressure-sensitive adhesive is used to re-adhere the marginal region to an underlying surface of the inner structure adjacent the opening through the laminate.
US10543969B2 Carrier for containers
A carrier for holding at least one container includes a plurality of panels extending at least partially around an interior space of the carrier and including a front panel, a back panel, at least one side panel, a first bottom panel, a second bottom panel, and at least one central panel. At least one divider flap extends from the at least one central panel to at least one of the front panel and the back panel. The first bottom panel includes at least one male locking feature and the second bottom panel includes at least one female locking feature for receiving the at least one male locking feature. The at least one male locking feature engages the at least one divider flap to lock the at least one divider flap in a generally perpendicular position relative to the central panel.
US10543968B2 Low profile, wrappable elongate members spacer and method of maintaining elongate members in fixed, spaced relative relation
A low profile, wrappable spacer and method for maintaining a pair of elongate members in fixed, spaced relation to one another is provided. The wrappable spacer includes a flexible elongate body having oppositely facing inner and outer faces extending along laterally spaced, lengthwise extending edges between opposite ends. The inner face has an adhesive surface. At least one member extends between the edges transversely to the lengthwise extending edges. The member extends outwardly from the adhesive surface, wherein the adhesive surface is configured for adhesion to at least one of the member, the elongate members or the outer face.
US10543965B2 Child-resistant smoking article package
A child-resistant smoking article package 100 is provided which comprises a case 103 with an opening 104 that is adapted to receive a smoking article 102 and a cap 107 movable between a closed state wherein the cap 107 closes the case 103 and an open state wherein the opening 104 of the case 103 is accessible. The child-resistant smoking article package 100 further comprises a first releaseably engageable fixation member 108-1 and a second and third releaseably engageable fixation member 108-2, 108-3, wherein the second and third releaseably engageable fixation members 108-2, 108-3 are arranged on opposing sides of the child-resistant smoking article package 100. The first, second and third releaseably engageable fixation members 108-1, 108-2, 108-3 are adapted to immovably fix the cap 107 to the case 103 in the closed state and to release the cap 107 when they are simultaneously actuated.
US10543962B2 Container and cap assembly
A cap assembly for a container has an inner sleeve that is secured to the neck of the container and an outer cap that is adjustably secured to the inner sleeve. The outer cap can be adjusted downwardly relative to the inner sleeve so that a gap between the bottom of the outer cap and a top of the container can be minimized or eliminated.
US10543961B2 Container cap and production method for container cap
A container cap is a container cap including a molded article formed of a resin composition containing 70 to 94% by mass of a polyolefin (A), 3 to 15% by mass of an acid-modified polyolefin (B) and 3 to 15% by mass of a m-xylylene group-containing polyamide (C), in which a ratio (X/Y) of a percentage (X) of polyamide-derived nitrogen in a cap top surface portion to a percentage (Y) of polyamide-derived nitrogen in a cap side surface portion, is 1.2 to 3.0, as measured by a total nitrogen analysis.
US10543960B2 Lid for a beverage container
A lid with a stopper for use with a beverage container is described. The lid includes a lid body to fit into an opening of the beverage container. The lid includes a stopper to threadably engage with the lid body. A drink opening is formed between the lid body and the stopper. The stopper rotates between open and closed positions to open and close the drink opening. The stopper includes hook members. The hook members are movable relative to the stopper. The hook members releasably hold the stopper to the lid.
US10543959B2 Multiple zipper slider bag
A storage bag comprising first and second zipper profiles provided adjacent to an opening to the interior of the bag. The first and second zipper profiles are provided with opposing closure elements that respectively interlock with each other. The storage bag further includes first and second isolation sections between the first and second zipper profiles and a slider to occlude and to de-occlude the closure elements of the first and second zipper profiles. The slider includes a first zipper profile opening member and a support member with a second zipper profile opening member that is (i) disposed between the first and second isolation sections, and (ii) separate and distinct from the first zipper profile opening member.
US10543953B2 Storage case
To improve operability when an object to be stored is taken-out and stored and portability. A main case includes a first bottom-plate, a first side-wall, and a first space. The first side-wall includes four sides including a first side. The first side-wall includes a first side-plate opposite to the first side and is connected with three sides different from the first side. The first space is partitioned by the first bottom-plate and the first side-wall. The cap includes a second bottom-plate, a second side-wall, and a second space. The second side-wall has four sides including a second side. The second side-wall includes a second side-plate opposite to the second side and is connected with three sides different from the second side. The second space is partitioned by the second bottom-plate and the second side-wall and has a volume larger than a volume of the first space. The connection plate is connected with each of the first side and the second side and is foldable to the first bottom-plate and the second bottom-plate. The grip member is attached to the first side-plate and is capable of penetrating into the second side-plate in a closed state in which the first side-wall is housed in the second space.
US10543951B2 One-piece, foldable cooler
A cooler includes panels defining a storage area; corner panels; top panels forming a lid; a first handle panel connected to a first top panel and having a slot formed therein; a second handle panel connected to a second top panel and having a slot formed therein; and a first tab panel connected to a corner panel and having a tab defining a recess, the tab being configured to extend through the slot of the first handle panel and through the slot of the second handle panel for locking the handle panels and top panels in a fully closed, carry configuration of the cooler. Portions of the first and second handle panels are received within the recess defined by the tab. The second handle panel can be unlocked and the storage area accessed while holding the cooler with the first handle panel.
US10543950B2 Packaging with outer sleeve and slider
A package includes an outer sleeve and a slider for holding a blister pack slidably mounted within the outer sleeve. The outer sleeve includes a wall having an outer panel and an inner panel. The inner panel has a locking edge formed at a terminal end thereof spaced from and facing a closed end of the sleeve. A locking flap is formed at a terminal end of the slider extending in a direction away from a closed end of the outer sleeve for engagement with the said wall of the outer sleeve. The flap has a free edge for engagement with the locking edge of the inner panel to prevent the slider from being removed from the outer sleeve when the slider is fully received within the outer sleeve. The outer panel of the outer sleeve includes a release button at least partially overlapping the flap of the slider when the slider is fully inserted in the outer sleeve, and being pressable so as to disengage the free edge of the slider flap from the locking edge of the outer sleeve wall to permit the slider to be withdrawn from the outer sleeve.
US10543947B1 High-speed print-and-apply label applicator
A high-speed print-and-apply label applicator includes a conveyor system, a control and monitoring system, a label web feeding assembly, a label printer and encoder system, a tamp pad assembly driven by a linear motor having a shaft that is formed at least partially by a composite material.
US10543944B2 Methods for aseptic packaging of low-acid foods
The present disclosure relates to methods of maintaining sterility of an aseptic work zone of a blow-fill seal operation so that low acid foods may be aseptically processed and packaged. The methods of the present disclosure further provide for maintain the sterility of the aseptic work zone such that the aseptic work zone does not have to be enclosed in a separate sterile environment during the blow fill seal process. The methods of the present disclosure further provide a sterilization procedure that is compliant with FDA regulations related to the aseptic packaging of low acid food products. Further disclosed, are methods for producing a hermetically sealed container containing a low acid food product.
US10543943B2 Ultrasonic sealing apparatus for use in bag filling and packaging machine
A horn and an anvil are moved toward and away from each other by axially reciprocating a driving rod and thereby reciprocatingly rotating a forked lever in a predetermined angle range. The horn and the anvil are moved toward and pressed against each other with a predetermined force with a bag mouth b held therebetween. A sensor detects the position of a second mounting block secured to the rear end of a sliding shaft of the anvil, thereby detecting the distance between respective pressing surfaces of the horn and the anvil, i.e. the thickness m of a portion of the bag mouth held between the pressing surfaces. When the thickness m is not less than a predetermined threshold value M, a vibrator is activated to perform sealing. When the thickness m is less than the threshold value M, no sealing is performed.
US10543942B2 Product handling and packaging system
Embodiments of product handling systems facilitate transfer of individual product items from incoming bulk form into dedicated trays for inspection, sorting, selection, and packaging. Inspection may comprise interrogation of product items within a tray by electromagnetic (e.g., optical, hyperspectral) or other (e.g., physical, acoustic, gas sensing, etc.) techniques. Prior to packaging, product items disposed within the tray may be stored in a moveable carousel responsible for controlling environmental factors such as temperature, humidity, illumination, ambient gases, product-to-product interactions, and/or others. Movement of product items from a carousel's transfer station to an outside staging position may be accomplished using robots and/or conveyor belts. Embodiments may allow rapid, low-cost consumer selection of specific individual product items based upon their accompanying metadata (e.g., source, identifier), in combination with the results of inspection (e.g., visual appearance). Embodiments may receive product items pre-packaged in tray format to expedite inspection, sorting, selection, and packaging.
US10543937B2 Stationkeeping techniques for spacecraft in inclined geosynchronous orbit
A constellation of Earth-orbiting spacecraft, the constellation having an orbital maneuver lifetime life (OML), includes a first spacecraft disposed in a first orbit and a second spacecraft disposed in a second orbit, each of orbit being substantially circular with a radius of approximately 42,164 km and having a respective inclination with respect to the equator specified within a range of 10° to 20°. The first orbit has, at beginning of life (BOL), a first right ascension of ascending node (BOL-RAAN1) and the second orbit has, at BOL, a second RAAN (BOL-RAAN2) the BOL-RAAN1 and the BOL-RAAN2 being separated by a first angular separation Δ-RAAN1. A first stationkeeping delta-V (ΔV1) applied over the OML to the first spacecraft, in combination with a second delta-V (ΔV2) applied over the OML to the second spacecraft, maintains the Δ-RAAN1 approximately constant and an actual inclination within specification, and ΔV1 approximately equals ΔV2.
US10543935B2 Foreign object debris barrier for runways
A collapsible runway side barrier for preventing foreign object debris (FOD) from entering a runway and taxiway. The barrier may have an aerodynamic profile, one side of the barrier profile may be convex and the other side of the barrier profile may be concave. The side barrier may further have ground attachment elements and may be constructed to collapse if the landing wheels of an aircraft impact the barrier.
US10543932B2 System and method for modulating premature descent protection envelope
A system and method are provided for modifying the position or shape of a premature descent protection envelope with regard to a runway when an aircraft making an approach to the runway is below the nominal approach path and has a flight path angle greater than the nominal approach path angle.
US10543931B2 Method and system for contextually concatenating display, aural, and voice alerts
A method and system of monitoring aural and message alerts received during flight in an internet of things (IOT) cockpit of an aircraft generated by systems within the cockpit, the method includes: receiving a plurality of alerts which include at least one of an aural alert or message alert; applying a first natural language processing (NLP) process to the aural alert to convert the aural alert to a text alert consistent in structure with the message alert for aggregating together with the message alert to form a concatenated message alert; and identifying the context of the concatenated message alert by applying a second NLP process to the concatenated message alert in its entirety and subsequent tagging the concatenated message alert to associate a tagged message with a display element wherein the tagged message is a concatenated message.
US10543930B2 Systems and methods for providing augmented information for vehicle multi-function display electronics
Systems and methods for providing augmented information for vehicle multi-function display electronics are provided. In one a method for providing augmented information for vehicle multi-function display (MFD) electronics comprises: receiving via a downlink communication, a vehicle profile comprising an MFD Profile descriptive of how a pilot is currently utilizing a cockpit MFD; determining whether an MFD map application is displaying information on the cockpit MFD based on the MFD Profile; when the MFD map application is determined to be displaying information on the cockpit MFD: defining a set of potential information enhancements based on the vehicle profile; collecting information corresponding to the set of potential information enhancements from one of more data sources; transmitting an uplink communication comprising an Augmented Map Profile, wherein the Augmented Map Profile comprises the information corresponding to the set of potential information enhancements.
US10543929B2 Systems and method for air vehicles
A refueling device for use in in-flight refueling operation between a tanker aircraft and a receiver aircraft includes a selectively steerable body and a controller. The selectively steerable body configured for being towed by a tanker aircraft via a fuel hose at least during in-flight refueling, and includes a boom member having a boom axis and configured to enable fuel to be transferred from the fuel hose to a receiver aircraft along the boom axis during the in-flight refueling operation. The controller is configured for selectively steering the body to an engagement enabling position spaced with respect to the receiver aircraft and for aligning the boom axis in an engagement enabling orientation at the spaced position, and for subsequently moving the boom member along the boom axis towards the receiver aircraft for enabling fuel communication therebetween.
US10543925B2 Aircraft air conditioning system with a cabin exhaust air turbine
An aircraft air conditioning system comprising an ambient air line, for ambient air to flow through, connected to supply ambient air to a mixer of the aircraft air conditioning system. An ambient air compressor is arranged in the ambient air line for compressing the ambient air flowing there through. A refrigerating apparatus comprises a refrigerant circuit for a refrigerant to flow through, including a refrigerant compressor arranged in the refrigerant circuit. The refrigerant circuit is coupled thermally to the ambient air line to transfer heat from the ambient air to the refrigerant before the ambient air is supplied to the mixer. A cabin exhaust air turbine is connected to a cabin exhaust air line, is coupled to the ambient air compressor arranged in the ambient air line, and is configured to expand the cabin exhaust air flowing through the cabin exhaust air line and to drive the ambient air compressor.
US10543923B2 Seat backrest
A seat is disclosed. The seat includes a frame, a seat pan connected to the frame and a backrest. The backrest includes a main panel, an upper panel hingedly connected to the main panel and a lower panel hingedly connected to the main panel. The upper panel is connected to the frame and the lower panel is connected to the seat pan.
US10543920B2 Deployable foot rest assembly
A foot rest installation comprising a base structure that includes a footwell and may be provided under a seat, in a bulkhead or in a console, and a foot rest assembly. The foot rest assembly has a deployable foot rest support structure and a first foot rest component comprising a flexible structure, for example a net, having a first end fixed with respect to the base structure at a first location, and a second end coupled to the foot rest support structure at a second location that is spaced apart from the pivot axis along a front-to-rear axis. When deployed, the foot rest support structure extends downward and rearward from the pivot axis to deploy the net in the footwell. When stowed, the foot rest support structure extends upward and rearward from the pivot axis.
US10543919B2 Aircraft cabin and partition assembly therefor
A partition assembly (16) for an aircraft cabin, including a bulkhead (18) with first (28) and second (30) internal compartments having respective first (32) and second (34) open ends defined in a same side of the bulkhead (18), one of the compartments being located aft of the other, a sliding door (36) slidingly supported within the first compartment (28) and slidable out of the first compartment (28) through the first open end (32), and a curtain (42) slidingly engaged to a curtain rail (40), the curtain receivable in the second compartment (30) and slidable along the curtain rail (40) out of the second compartment (30) through the second open end (34). An aircraft curtain rail is also described where the curtain rail and curtain track each have a non-rectilinear profile when viewed in a first plane and when viewed in a second plane perpendicular to the first plane. A method of manufacturing a curtain rail is also discussed.
US10543915B2 Self-folding propeller
A propeller assembly includes propeller blades that self-fold when not in use, which reduces the overall footprint of the propeller assembly and enables efficient storage. During flying conditions, the propeller blades unfold and extend to a flight configuration that enables the generation of lift on the propeller blades and consequently to an attached aerial vehicle. In various embodiments, the transitioning of the propeller blades between a flight and folded configuration may be enabled by torsion springs coupled to each propeller blade. For example, the torsion springs cause each propeller blade to rotate and self-fold when no external forces are applied. Alternatively, during flying conditions, centrifugal forces that arise as the propeller assembly rotates counteract the torsion springs, enabling each propeller blade to achieve an extended flight configuration. Therefore, the propeller blades of the propeller assembly are optimally oriented without the need for human intervention.
US10543914B2 Non-loaded manual blade fold assembly
A rotor blade configured to fold about a blade fold axis includes a first section and a second section. The first section is configured to mount to a rotor hub and includes a first connector having at least one first opening. The second section includes a second connector having at least one second opening. The second section is rotatably coupled to the first section and is configured to rotate about the blade fold axis between an aligned position and a rotated position. A linkage is operably coupled to the first section and the second section. The linkage includes a plurality of links loosely connected such that the linkage is configured to support the second section of the rotor blade only when the second section is in the rotated position.
US10543913B2 Tri-hybrid yoke
A tri-hybrid yoke including a center ring connected to a CF fitting connected to flexure arms. An inboard centrifugal force bearing assembly connects to the CF fitting and a grip. An outboard shear bearing assembly connects to the flexure arm and the grip. In use, the center ring and the CF fittings carry the centrifugal force at a position inboard of the flexure arm.
US10543909B2 System and method for aircraft electric taxi brake optimization
Systems and methods for aircraft electric taxi brake optimization are provided. The system may comprise an aircraft having a landing gear comprising a wheel, a friction brake having a brake material coupled to the wheel, a regenerative brake comprising a reversible taxi motor coupled to the wheel, a sensor configured to measure a wheel parameter of the wheel and a temperature of the friction brake, a tangible, non-transitory memory configured to communicate with a controller, the tangible, non-transitory memory having instructions stored thereon that, in response to execution by the controller, cause the controller to perform operations comprising: receiving, by the controller, a command signal and the friction brake temperature and calculating, by the controller, a brake material temperature based on the wheel parameter, the friction brake temperature, and the command signal.
US10543908B2 Vortex generator arrangement for an aircraft
A vortex generator arrangement for an aircraft, a flow control system and an aircraft comprising such vortex generator arrangement. The arrangement includes a surface portion facing a first region of space to constitute a flow surface, a vortex generating element, an element support structure connected to the element, a mounting structure. The element support structure and the element together are rotatable between first and second positions and a biasing device, retainer and release are provided. The rotational axis extends transversely with respect to the surface portion. The projection of the element onto a projection plane is smaller in the first rotational position than in the second rotational position, the projection plane extending perpendicularly to a tangent plane of the surface portion at a reference point of the surface portion and to a predetermined direction parallel to the extension of the tangent plane.
US10543905B1 Battery shifting for center of gravity control
In an embodiment, a system for battery shifting for center of gravity (CG) control includes a battery holder and a controller. The battery holder is adapted to change between a first battery position and a second battery position in a vehicle. The battery holder being in the first position causes the vehicle to have a first CG and the battery holder being in the second position causes the vehicle to have a second CG. The controller is configured to move the battery holder into the first position at least some of the time when the vehicle is flying at a first angle such that the vehicle has a CG in a first vehicle location, and move the battery holder into the second position at least some of the time when the vehicle is flying at a second angle such that the vehicle has a CG in a second vehicle location.
US10543896B2 Decompression device
A decompression device has at least one decompression member which is arranged on a supporting structure and which, in the event of differential pressure of a predetermined level, opens an opening in the supporting structure that acts as a connection between two volumes, wherein the decompression member can move between a retention position, in which the decompression member closes the opening, and a released position, in which the decompression member opens the opening, and has a locking arrangement which, when in use, fixes the decompression member in the retention position. The locking arrangement is provided with at least one locking element, which is arranged on the supporting structure, and the decompression member is kept in the retention position indirectly by the locking element interacting with an air conduction part.
US10543894B2 Self-powered standup personal watercraft
A watercraft includes left and right hull members that are held in spaced apart, parallel relation by a supporting frame structure. A pendulum propulsion assembly mounts to the frame structure, between the hull members, and includes left and right pendulum assemblies that are each movable in a forward and rear direction by the operator's arms and legs. Each pendulum assembly includes at least a forward pendulum member extending through an upper pivotal connection to a lower pivot element coupled to a horizontal pendulum plane. A paddle holder mounted below the pendulum plane supports an arrangement of spaced paddles. Operation of the left and right pendulum assemblies in the forward and reverse alternating action through a normal stride causes the paddles to propel the watercraft in a forward direction. Forward flexing of the paddles in the power stroke is limited by tethers connecting between the paddles and the paddle support.
US10543893B2 Undersea vehicle and method for operating a reactor
The present invention includes an underwater vehicle power unit and method of operating the same comprising: a fuel and waste stack comprising one or more reactant or fuel storage bladders and one or more waste storage bladders; a heater; a reactor that generates hydrogen and waste; a hydrogen and waste separator; a back-pressure regulator; a hydrogen and liquid separator; a fuel cell; and a controller that controls the temperature of the heater, the flow of fuel into the reactor, the flow of hydrogen into the fuel cell, the flow of water that dilutes the fuel, the flow of waste from the reactor and/or the fuel cell into the one or more waste storage bladders.
US10543889B2 Fender for boats consisting of two components made of PVC coupled by a lock joint
A fender for boats consisting of a base made of plastic material able to be fixed to a hull of a boat, and an insert made of plastic material able to be coupled by a lock joint to the base. The insert comprises two wings, two connection protrusions, a central body and two outer grooves between each wing and the respective connection protrusion.
US10543888B2 Buoy assembly
A buoy assembly for use in water activities includes a shell that defines an interior space. The interior space is substantially empty so that the shell is buoyant. A net is positioned around and coupled to the shell. Each of opposing ends of a line is coupled to the net. A fastener, which is slidably coupled to the line, defines a wrist loop that is positioned distal from the shell. The fastener is selectively fixedly couplable to the line so that the fastener is positioned to be selectively slid on the line toward a wrist of user that is positioned in the wrist loop. The fastener is positioned to fixedly couple to the line to couple the shell to the user.
US10543879B2 Small-vehicle direction indicator device
A small-vehicle direction indicator device includes a directional signal light for small vehicles, such as saddle riding type vehicles, the directional signal light including a lighting unit and a plurality of light sources that are arrayed in the lighting unit in a vehicle width direction. The small-vehicle direction indicator device performs a dynamic direction indication by chain-reactive switch-ons or switch-offs of the plurality of light sources when the directional signal light is activated. In the directional signal light, between the plurality of light sources, a light-blocking wall made of an opaque member is arranged, and wherein a plurality of the light-blocking walls are arrayed in the vehicle width direction.
US10543878B2 Seat for a vehicle
The present invention regards a seat for a vehicle, a bicycle, a stationary bicycle or a motorcycle including a base group, a top group and removable engagement means between base group and top group.
US10543875B2 Extendable trailer for freight containers
A trailer for transporting a container has a frame mountable to a vehicle. The frame has a rear frame section mountable above a rear wheel assembly of the trailer, and a front frame section connected to and disposed forward of the rear frame section in a forward direction of travel of the vehicle. The front frame section has a king pin mountable to a hitch of the vehicle and a forward-most end. The forward-most end is moveable relative to the kingpin in a direction parallel to the forward direction of travel to extend and shorten a length of the front frame section between a fully-lengthened configuration and a fully-shortened configuration.
US10543863B2 Mobile cart for an organ container
Disclosed is a mobile cart for an organ container. The mobile cart includes a top assembly configured to be releasably secured to the organ container, which is at least one of an organ transporter and an organ perfusion apparatus configured to perfuse an organ. It also includes a support structure attached to the top assembly so as to support the top assembly, the support structure being moveable from an extended position to a collapsed position. The top assembly in turn includes distinct primary and secondary locking mechanisms, each of which is configured to secure the support structure in the extended position. And when the support structure is secured in the extended position, both the primary and secondary locking mechanisms must be actuated for the support structure to be moveable to the collapsed position.
US10543862B1 Load-bearing assembly
The present invention is generally a load-bearing assembly that may be expanded so as to increase a surface area on which to support different sized loads. The load-bearing assembly may be constructed with multiple T-shaped frames or housings that register with each other forming a unique H-shaped frame design. The two T-shaped housings register with each other in a manner that facilitates the adjustment of the width of the load-bearing assembly. Extensions enclosed within each housing and extendable at terminal ends of each T-shaped housing extend outwardly from their respective terminal ends to adjust a length of the load-bearing assembly. The load-bearing assembly may be constructed of a light, sturdy metal alloy that is lightweight. Applications include moving inventory inside warehouses or moving furniture or appliances from one location to another.
US10543861B1 Vertical rail measurement device
The invention relates to a portable device for measuring vertical rail measurements under service to record and report excessive vertical rail movement to prevent a train from derailing. The device may be pivoting with a tilt sensor and light-weight. The device may include a microprocessor, sensors, and a display. The device may be installed on the rail. The device may sense an approaching train, automatically turn on the device, and measure the real-time vertical displacement and the maximum/minimum vertical movement of the rail while the train is operating over the rail at all speeds.
US10543860B2 Vehicle communication system
A communication system includes a first communication device disposed onboard a displaced vehicle. The first communication device communicates with a second communication device onboard a lead vehicle of a vehicle system for the lead vehicle to remotely control operation of the vehicle system. The first communication device receives a reconfiguration signal from the second communication device. A remote control (RC) communication device is disposed onboard the first displaced vehicle. The RC communication device wirelessly receives a control signal from an operator control unit (OCU) for the OCU to remotely control the first displaced vehicle. A communication controller reconfigures the RC communication device to repeat the control signal from the OCU responsive to the first communication device of the first displaced vehicle receiving the reconfiguration signal from the second communication device of the lead vehicle or another reconfiguration signal from an off-board or on-board location.
US10543859B2 Railway wheels monitoring system and method
It is described a system and method to monitor railway wheels, which includes obtaining images of the railway wheel by means of stereo cameras and performing a three-dimensional and two-dimensional model of the railway wheel by means of these images. This two-dimensional model is subjected to analysis of the profile of the railway wheel, comparing it with a two-dimensional model of an ideal wheel and thus measuring the effective wear of its profile. The three-dimensional model is subjected to analysis of the surface of the railway wheel, also comparing it with a three-dimensional model of an ideal wheel and thus measuring the effective wear of its surface.
US10543855B2 Rail vehicle
A rail vehicle includes an electric drive including a housing and power semiconductors arranged in the housing, and a braking system configured for operation with compressed air. The housing and the braking system are interconnected such as to enable supply of compressed air from the braking system to an interior of the housing. A depressurization device is arranged between the housing and the braking system such as to enable compressed air which is supplied to the housing to be depressurized prior to being supplied to the interior of the housing.
US10543854B2 Gaze-guided communication for assistance in mobility
The invention assists a person in acting in a dynamic environment. A method and a system for assisting a person operating an ego-vehicle a person supporting the operation of the ego-vehicle in a dynamic environment such as a traffic environment is proposed. The method encompasses determining a gaze direction of the person and identifying a target object based thereon, generating prediction information predicting a future behavior of the target object and the ego-vehicle, estimating a time-to-event or a distance or a distance variation for the ego-vehicle and the target object and generating a signal for driving an actuator and indicative of the estimated time-to-event, distance or distance variation. The actuator causes a stimulation being perceivable by the person by its perceptual capabilities based on the generated signal. The method determines whether assistance for assessing the dynamic situation is requested, for example by monitoring a gaze behavior of the person.
US10543849B2 Vehicle operational diagnostics and condition response system
A vehicle operational diagnostics and condition response system includes at least an axle supporting a vehicle frame, a suspension disposed between and secured to each the vehicle frame and the axle, a load detection device interacting with the suspension and communicating with a system controller, wherein the system controller is supported by the vehicle frame, and a vehicle operational lighting system supported by the frame and communicating with the system controller. The vehicle operational lighting system is activated by the system controller in response to load detection data received by the system controller from the load detection device.
US10543844B2 Controlling driving modes of self-driving vehicles
A method controls an operational mode of a self-driving vehicle (SDV). One or more physical detectors detect an erratically driven vehicle (EDV) that is being operated in an unsafe manner within a predetermined distance of an SDV that is initially being operated in an evasive autonomous mode. One or more processors retrieve traffic pattern data for other SDVs, and examine the traffic pattern data to 1) determine a first traffic flow of the other SDVs while operating in the evasive autonomous mode, and 2) determine a second traffic flow of the other SDVs while operating in a manual mode. In response to determining that the first traffic flow has a higher accident rate than the second traffic flow, an operational mode device changes the operational mode of the SDV from the evasive autonomous mode to the manual mode.
US10543836B2 Torque converter control for a variable displacement engine
Systems and methods for operating an engine and a torque converter are presented. In one example, slip of a torque converter is adjusted via at least partially closing or opening a torque converter clutch in response to vehicle vibration. The vehicle vibration may be based on road surface conditions and an actual total number of operating cylinders of the engine.
US10543835B2 Hybrid vehicle
A hybrid vehicle is provided. In the hybrid vehicle an oil pump can be driven while stopping an engine without a device for interrupting torque transmission between a power split device and the engine. A differential mechanism includes a first rotary element to which torque is delivered from the engine, a second rotary element connected to drive wheels, and a third rotary element to which torque is delivered from the first motor. Torque transmission between the first motor and the third rotary element is interrupted by a clutch. A mechanical oil pump is driven by any one of the first input shaft and the second input shaft that is rotated higher than the other one.
US10543831B2 Vehicle control apparatus
A control apparatus for a vehicle provided with a motor/generator functioning as a drive power source, and a mechanically operated transmission mechanism which constitutes a part of a power transmitting path between the motor/generator and drive wheels, the control apparatus including a motor/generator control portion configured to implement a regenerative torque control of the motor/generator so as to generate a regenerative torque according to a braking operation by an operator of the vehicle in a decelerating run of the vehicle, and a transmission shifting control portion configured to initiate a shift-down action of the mechanically operated transmission mechanism after a rate of change of the regenerative torque has been held within a predetermined range for at least a predetermined length of time, where a determination to implement the shift-down action is made in the process of the regenerative torque control of the motor/generator according to the braking operation.
US10543829B2 Hybrid vehicle including electronic control unit configured to correct base driving force using correction driving force
A hybrid vehicle includes an engine, a first motor, a planetary gear mechanism, a second motor, a battery, and an electronic control unit. The electronic control unit is configured to: set a shift stage based on a depression amount of an accelerator and a vehicle speed or a driver's operation; set a base driving force based on the degree of the depression amount of the accelerator, the vehicle speed, and a target rotation speed; set a correction driving force such that the correction driving force increases with an increase in elapsed time after upshifting or an increase in the vehicle speed after upshifting when the shift stage upshifts; and control the engine, the first motor, and the second motor such that a driving force obtained by correcting the base driving force using the correction driving force is output to the drive shaft.
US10543827B2 System for accessing integral pressures of brake control valve
A distributor valve for a brake control system of a railway vehicle is provided with an access interface that includes a plurality of access ports for measuring the operational pressures of the distributor valve. The distributor valve includes a pipe bracket and a main line and main portions mounted on the pipe bracket. The pipe bracket includes a plurality of passages for communicating the main portion and the main line portion with each other and with a brake pipe, brake cylinder, and reservoir of the brake control system. The plurality of access ports of the access interface includes ports in communication with the working chamber passage, valve chamber passage, brake pipe passage, reservoir passage, and the brake cylinder passage of the pipe bracket.
US10543823B2 Pneumatic brake booster having a recessed bearing surface
In order to minimize spreading, without additional parts, of connecting bolts of a pneumatic brake booster in a manner which is brought about by the deformation of a bearing surface on a booster housing before and during its assembly on a provided vehicle body part, it is proposed that the bearing surface is assigned a planar surface section in an immediately adjacent manner which is configured so as to be plane-parallel with respect to the bearing surface and so as to be axially inwardly recessed on the booster housing with a circumferential step.
US10543821B2 Liquid reservoir for vehicle and motor vehicle system comprising such a reservoir
The present invention relates to a liquid reservoir for a vehicle that is subjected in service to inclinations in at least two different directions, the reservoir comprising a float well which delimits a bowl containing a float that is able to move depending on the level of liquid in the reservoir. The reservoir is characterized in that the float well comprises at least two retention means positioned successively along a flow path of the liquid as far as the bowl, from the outside toward the inside of the float well, each retention means keeping liquid in the float well if the reservoir is inclined in a set of directions specific to this retention means. The invention also relates to a motor vehicle system comprising such a liquid reservoir and means for binary detection of the level of liquid in the reservoir.
US10543819B2 Hydraulic braking system
A power-assisted hydraulic braking system includes a main brake line into which a setpoint brake pressure can be introduced via a brake valve actuated by a brake pedal, and from which a plurality of wheel brake lines branch off, each leading to an actuating unit of a wheel brake, and a valve arrangement of an ABS controller, comprising an inlet valve disposed between the main brake line and one of the wheel brake lines and an outlet valve disposed between the relevant wheel brake line and a pressureless return line. The inlet valve and the outlet valve are embodied as pressure-controlled 2/2-way switching valves with suitably sized switching cross-sections. At least one pilot control valve is associated with each of the inlet valve and the outlet valve, via which a control connection can be alternately subjected to a low or high control pressure to change over.
US10543818B2 Stability control system and method for four-wheel drive electric vehicle, and electric vehicle
The embodiments of the present application disclose a stability control system and a stability control method for a four-wheel drive electric vehicle and the four-wheel drive electric vehicle. In the stability control system, when the lateral acceleration is equal to or greater than an acceleration threshold, at least one of a first braking force signal, a second braking force signal, a first logic signal and a second logic signal is obtained. When the first logic signal is obtained, the body of the electric vehicle is controlled to keep stable. When the first braking force signal and the second logic signal are obtained, a motor is controlled to apply braking force to an outside front wheel. When the second braking force signal and the second logic signal are obtained, motors are controlled to apply braking force to the outside front wheel and an inside rear wheel.
US10543817B2 Powered rear outrigger systems
An outrigger system includes an outrigger frame, a pair of hydraulic cylinders coupled to the outrigger frame, a pair of rear outriggers coupled to the outrigger frame and coupled to respective hydraulic cylinders, and a pair of multi-arm assemblies coupled to respective rear outriggers and respective hydraulic cylinders and arranged to permit the pair of rear outriggers to rotate, with respect to the outrigger frame, among a first stowed position, a first fully deployed position, and a first site transportation position via extension and retraction of the pair of hydraulic cylinders.
US10543816B2 Systems for stabilizing a vehicle and method for stabilizing a vehicle
The invention relates to methods and systems for stabilisation of a vehicle with a chassis including a rear wheel bogie, a pendulum shaft rotatable through rotary bearings around an axis parallel to the longitudinal direction of the vehicle, a tipping arrangement on which a crane is arranged, and a stabilisation arrangement having first and second hydraulic stabilisation actuators in the rear wheel bogie. The tipping arrangement includes a rotating disk and rotary bearings, such that the rotating disk and crane are rotatable around a vertical axis, and first and second hydraulic tipping actuators in connection with the rotating disk, that can be rotated around a horizontal axis. The first stabilisation actuator and first tipping actuator are in fluid-mediated connection, and the second stabilisation actuator and second tipping actuator are in fluid-mediated connection. The stabilisation actuators are controlled based on the pressure at the tipping actuators.
US10543815B2 Adapter for connecting the free end of a wiper arm, and assembly comprising an adapter and a wiper arm
An adapter for connecting a wiper blade to a U-shaped front end hook of a wiper arm includes a front body with convex external profile, configured to be received in a concave front closed-end of the end hook, at least one branch which extends longitudinally towards the rear from the front body and which carries a single projecting locking stud intended to be received in a locking slot of the end hook, of the wiper arm, and at least two transverse notches for the longitudinal positioning of the adapter. The at least two notches are longitudinally offset relative to one another. One or another of the at least two notches collaborates with a transverse edge of the end hook according to a dimension of the end hook. The locking stud is configured to push against the end hook in a first longitudinal direction.
US10543811B2 Wiper system and wiper system control method
A wiper system performs operation control on wiper driving electric motors and based on position information about wiper blades and attached to pivot shafts, wherein a learning mode in which a position of the wiper blades is learned to correct blade position information is executed after the wiper blades are attached to the pivot shafts, respectively. In the learning mode, the wiper blades are moved to a prescribed position such as a lower retracted position, and that the wiper blades are located in the prescribed position is detected by such means as a sensor, a video image, and contact with a jig. If the wiper blades are detected to be in the prescribed position, the blade position information is corrected to a value corresponding to the position.
US10543809B1 Systems and methods for identifying unauthorized vehicle use
Various arrangements for monitoring the unauthorized use of a vehicle are presented. An in-space parking sensor may be used to detect whether a vehicle is present. An indication of a time period during which the vehicle is expected to be within the parking space may be received. Using the sensor data obtained from the parking sensor, a vehicle departure from the parking space may be detected. A determination may be made that the vehicle departure is unauthorized due to the vehicle departure occurring during the time period. An alarm indication may be output based on determining that the vehicle departure is unauthorized.
US10543802B1 Center console restraint system
A restraint system includes a center console and an airbag inflatable upwardly from the center console. The airbag includes an internal panel defining two chambers. The internal panel includes a plurality of tubes, and each tube includes an opening at which that tube terminates. The openings are proximate a top of the airbag and open to the chambers.
US10543800B2 Side airbag device for a vehicle
A side airbag device for a vehicle includes a lower chamber and an upper chamber to protect a passenger from a side impact in the event of a vehicle collision. The upper chamber is bent towards the passenger by a connecting tether to support a passenger's neck region and prevent the neck from being twisted. The restraint belt forms an inserting space in front of a passenger when the upper chamber is bent so that a passenger's shoulder region is inserted into the inserting space when the passenger is moved forwards by collision inertia. The passenger's shoulder region is surrounded and supported by the restraint belt so that the passenger's body is restrained by a seat. A passenger is protected from impact and simultaneously the passenger is restrained by the seat to minimize an injury.
US10543797B2 Bumper used in a motorized vehicle
A retrofitting bumper that is intended to be used in motorsports and in the vehicular industry consists of a main structural bar, a first pair of support bars, and a second pair of support bars. Preferably, the main structural bar is manufactured from ultra-high-molecular-weight polyethylene (UHMWPE) so that the memory shape behavior allows the main structural bar to retain the original shape even after impact. The first pair of support bars and the second pair of support bars are terminally and angularly mounted along a structural body of the main structural bar. A fastening mechanism, a first pair of attachment brackets, and a second pair of attachment brackets are used to mount the main structural bar, the first pair of support bars, and the second pair of support bars onto the frame of the ATV.
US10543793B2 Decorative part and method for producing a decorative part
A decorative part for an interior trim of a motor vehicle includes a carrier layer and a covering layer. The covering layer is arranged on the carrier layer. The covering layer has a higher fraction of natural fibers than the carrier layer and is mechanically connected to the carrier layer by needle punching.
US10543789B1 Combination cargo stop and step
A tailgate includes an opening through a rear end of the tailgate when in a tailgate open position. The tailgate also includes a tailgate extender having support tubes extending through the opening and telescopically slidable outward from the tailgate, a laterally extending support beam supported by the support tubes, and a cargo-assist step pivotally mounted to the support beam, the cargo-assist step configured to pivot downwardly when the support tubes are pivoted downwardly to define a step and to pivot upwardly into a vertical position when the support tubes extend horizontally to define a cargo stop.
US10543781B2 Light-emitting device
A light-emitting device includes a board, a light-emitting element mounted on a surface of the board, a support member on which the board is placed, and a cover having a plate shaped main cover body covering the light-emitting element and a tubular portion which receives a light guide body that guides light emitted from the light-emitting element. The main cover body includes a base, a protrusion protruding from the base toward the board, and a ridge disposed on a protruded end of the protrusion. A step is formed by the protrusion and the ridge, and the protrusion and the ridge extend in a same direction along the base.
US10543780B2 Illumination apparatus
Non-emergency illumination apparatus (10) arranged in use to mark a location of an article, fixture or fitting in an aircraft cabin, the apparatus including: an emitting layer (2) including a photoluminescent material, the photoluminescent material emitting visible light in a first region of the electromagnetic spectrum in response to excitation by light from a second region of the electromagnetic spectrum, different to the first region; and a protective layer (6) overlying the emitting layer, the protective layer transmitting light from the first and second regions of the electromagnetic spectrum, wherein the non-emergency illumination apparatus is constructed and arranged to be placed in proximity to an article, fixture or fitting, such that the apparatus marks the location of the article, fixture or fitting when excited by light from the second region of the electromagnetic spectrum. The illumination apparatus can comprise a carrier matrix. The illumination apparatus aids location of items such as headphone sockets and power sockets in low lighting conditions so calming passengers.
US10543775B2 Lighting control method, lighting control device and vehicle
A lighting control method for use in a first vehicle is provided. The method includes receiving an optical signal from a lamp of a second vehicle; identifying a pulse signal included in the optical signal; determining a position of the second vehicle relative to the first vehicle; and controlling a lamp of the first vehicle in accordance with the position of the second vehicle and the pulse signal.
US10543771B2 Vehicle rooftop rack assembly
An assembly for mounting a platform to a vehicle rooftop is disclosed. The assembly includes a rail mounted on a bottom side of the platform, having a linear track. A clamp assembly is slidably mounted in the linear track, and is configured to grip a crossbar. The clamp assembly includes a fixation device configured to stop movement of the clamp assembly in a selected position along the track.
US10543768B2 Adjustable armrest systems and methods for a material handling vehicle
Provided are systems and methods for adjusting an armrest assembly, the assembly comprising an armrest that includes an armrest pad, a rising platform having a nut aperture, a nut positioned within the nut aperture. The assembly further includes a rod assembly coupled with the armrest, an adjustment mechanism for raising or lowering the armrest, and may include one or more rotation stops coupled with a stationary plate.
US10543767B2 Cushion pan and vehicle seat
A cushion pan for a seat cushion is formed from a metal sheet and the cushion pan includes: an outer frame section that is formed in a frame shape in a seat plan view, a pair of mutually opposing sides of the outer frame section each including a horizontal portion with a respective thickness direction along a seat up-down direction; a pair of side plate portions that extend toward one side in the seat up-down direction from facing end portions of the pair of horizontal portions; and a plate spring portion having a flat plate shape bridging between ends of the pair of side plate portions on an opposite side of the side plate portions from the pair of horizontal portions.
US10543764B2 Vehicle seat and stiffness setting method for vehicle seat
A vehicle seat (1) includes a seat cushion (2) and a seat back (3), in which the seat cushion (2) is given a stiffness distribution in a front-rear direction in such a way that a front part of the seat cushion is provided with a low stiffness region (PSc) which is more flexible than a rear part of the seat cushion being a high stiffness region (PHc).
US10543763B2 Clip
A clip for attaching a seat cover to a seat cushion includes a locking part configured to be secured to the seat cover and a hook connected to the locking part and configured to be secured to a wire of the seat cushion. The hook defines a wire holding cavity.
US10543756B2 Detecting an arrangement based on predefined signatures in an inductive power transfer system
A secondary unit arrangement of an inductive power transfer system includes a secondary unit having a secondary winding structure for receiving a magnetic or electromagnetic field generated by a primary unit, a detector device including plurality of detection elements for detecting an arrangement comprising the primary unit, a determination unit for determining at least one electrical property of the detector device with respect to different regions of an arrangement, thereby generating determination results consisting of a determination result for different regions of the arrangement, a comparison unit for comparing the determination results with existing information about the arrangement to be detected, wherein the existing information includes information about expected values for the different regions of the arrangement, thereby generating a comparison result, and a decision unit for deciding from the comparison result whether the determination results indicates that the detector device has detected the arrangement as expected.
US10543755B2 Apparatus and method for rapid charging using shared power electronics
An apparatus comprises a power electronic energy conversion system comprising a first energy storage device configured to store DC energy and a first voltage converter configured to convert a second voltage from a remote power supply into a first charging voltage configured to charge the first energy storage device. The apparatus also includes a first controller configured to control the first voltage converter to convert the second voltage into the first charging voltage and to provide the first charging voltage to the first energy storage device during a charging mode of operation and communicate with a second controller located remotely from the power electronic energy conversion system to cause a second charging voltage to be provided to the first energy storage device during the charging mode of operation to rapidly charge the first energy storage device.
US10543752B2 Light electric vehicle ride share system and method
Methods and systems are described for operating an interconnected network of autonomous battery powered electric vehicle (BEV) charging stations that maintain fully charged BEVs, for real-time self-guided exchange or rental with little down-time to a user. By locking or otherwise disabling low charge or uncharged vehicles until the vehicle charging is complete, users are assured they are getting a vehicle that has enough charge to get them to their destination. The user can view all available vehicles and their locations using a wireless mobile device on the system network and, with appropriate permissions, reserve and unlock any available vehicle via wireless networking. The locations in a ride share system of docking hubs with electrical power for re-charging BEVs is determined by the commute needs (particularly last mile commute needs) of users of the ride share system as they subscribe to the ride share program which utilizes the system.
US10543750B2 Vehicle
A vehicle includes: a solar panel; a power storage device configured to store electric power generated by the solar panel; and a control device configured to control charging and discharging of thee power storage device such that a state of charge of the power storage device is in a range between an upper limit value and a lower limit value. The control device is configured to set the upper limit value to be larger when an external power supply mode in which the electric power generated by the solar panel is supplied to the outside of the vehicle via the power storage device is selected than when the external power supply mode is not selected.
US10543743B1 Drive and cooling system for utility vehicle
A utility vehicle having a combined generator and coolant circulating pump assembly and at least one combined hydraulic pump and circulating pump is disclosed herein. An auxiliary pump may be disposed on a second hydraulic pump on the vehicle. A plurality of coolant reservoirs may be provided on the vehicle. The vehicle may also include a receiver for receiving signals from a remote operator transmitter, permitting remote operation of the vehicle, and an operator platform for permitting direct user control.
US10543740B2 Lockup clutch for powersplit hybrid transmission
A powertrain includes an engine and an electric machine. The powertrain further includes a planetary gearset including a a first rotatable element fixedly coupled to an engine crankshaft, a second rotatable element fixedly coupled to the electric machine, and a third rotatable element driveably connected to an intermediate shaft. The powertrain further includes a lockup clutch configured to selectively couple two of the first rotatable element, the second rotatable element, and the third rotatable element.
US10543739B1 Mode transition control techniques for an electrically all-wheel drive hybrid vehicle
Control techniques for an electrically all-wheel drive (eAWD) hybrid vehicle involve determining whether to transition from an electric-only mode to a parallel mode based on a driver torque request or a state of charge (SOC) of a battery system. During the electric-only mode, the electric motor is operated such that a torque reserve is maintained. When the driver torque request exceeds a maximum drive torque that the electric motor is capable of generating, the electric-only to parallel mode transition is performed. This involves the electric motor depleting the torque reserve to provide an expected acceleration feel for the driver while engine and transmission speeds are synchronized. When the SOC of the battery system falls below an SOC threshold, the drive torque of the electric motor is decreased to zero upon engine/transmission speed synchronization such that the battery system can be recharged.
US10543738B2 Hybrid powertrain, method for controlling such a hybrid powertrain, vehicle comprising such a hybrid powertrain, computer program for controlling such a hybrid powertrain, and a computer program product comprising program code
The present invention relates to a hybrid powertrain and method of controlling same, the hybrid powertrain comprising an internal combustion engine; a gearbox with an input and an output shaft; a range gearbox connected to the output shaft; a first planetary gear connected to the input shaft; a second planetary gear connected to the first planetary gear; a first electrical machine connected to the first planetary gear; a second electrical machine connected to the second planetary gear; one gear pair connected with the first planetary gear and the output shaft; and one gear pair connected with the second planetary gear and the output shaft, wherein the internal combustion engine is connected with the first planetary gear via the input shaft. The range gearbox comprises a third planetary gear with a third sun wheel and a third planetary wheel carrier and a fourth clutch device arranged to connect and disconnect the third sun wheel with/from the third planetary wheel carrier.
US10543735B2 Hybrid commercial vehicle thermal management using dynamic heat generator
A system and method are provided for hybrid electric internal combustion engine applications in which a motor-generator, a narrow switchable coupling and a torque transfer unit therebetween are arranged and positioned in the constrained environment at the front of an engine in applications such as commercial vehicles, off-road vehicles and stationary engine installations. The motor-generator is preferably positioned laterally offset from the switchable coupling, which is co-axially-arranged with the front end of the engine crankshaft. The switchable coupling is an integrated unit in which a crankshaft vibration damper, an engine accessory drive pulley and a disengageable clutch overlap such that the axial depth of the clutch-pulley-damper unit is nearly the same as a conventional belt drive pulley and engine damper. The front end motor-generator system includes an electrical energy store that receives electrical energy generated by the motor-generator when the coupling is engaged. When the coupling is disengaged, the motor-generator may drive the pulley portion of the clutch-pulley-damper to drive the engine accessories using energy returned from the energy store, independent of the engine crankshaft.
US10543733B2 Heating, ventilation, and air conditioning system of a work vehicle
A heating, ventilation, and air condition (HVAC) system of a work vehicle includes a housing configured to mount to a structure of a cab of the work vehicle. The housing includes at least one mounting assembly configured to support at least one heat exchanger within the housing, and the at least one mounting assembly is configured to position the at least one heat exchanger such that the at least one heat exchanger extends through the structure from an interior of the cab to an exterior of the cab while the at least one heat exchanger is coupled to the at least one mounting assembly.
US10543732B2 Vehicle air-conditioning unit
A vehicle air-conditioning unit has an air conditioning case and a case interior member. The air conditioning case defines a case passage in which air flows toward a vehicle compartment. The air conditioning case has a recess defining portion that is located in the case passage and defines a recessed portion. The case interior member has a guide portion and a cover. The guide portion guides the air flowing in the case passage. The cover is located in the recessed portion. The cover prevents the air, flowing in the case passage, from flowing into the recessed portion.
US10543729B2 End mount assemblies as well as gas spring and damper assemblies including same
End mount assemblies include a mounting bracket dimensioned for securement to an end member of a gas spring and damper assembly. The end mount assembly can include an inner mounting element dimensioned for securement to an elongated damping rod of the gas spring and damper assembly. A first plurality of bushing elements can be operatively disposed between the inner mounting element and the mounting bracket. A second plurality of bushing elements can be operatively disposed between the inner mounting element and the end member. Gas spring and a damper assemblies including such an end mount assembly as well as suspension systems and methods of assembly are also included.
US10543728B2 End plate of suspension member
There is provided an end plate that includes a through hole that causes an outer wall portion and an inner wall portion to communicate with each other, into which an intruding portion provided in a wheel-side member can intrude, a first press-formed portion formed by depressing in a peripheral edge of the through hole in the inner wall portion. The end plate includes a second press-formed portion arranged in a part of a peripheral edge on the side of a peripheral end of the inner wall portion, which is a remnant of a portion where the first press-formed portion is arranged in the inner wall portion, and formed therein with a protruding portion by protruding a part of the peripheral edge, and a screw hole formed by penetrating through the protruding portion in the second press-formed portion between the outer wall portion and the inner wall portion.
US10543724B2 Wheel rim accessory and method for assembling thereof
A wheel rim accessory assemblable to a wheel of a vehicle, including: (a) a casing having an outlet adapted to be in fluid communication with the internal volume of the wheel, the casing being assemblable to the wheel rim of the wheel; (b) a filler substance disposed within the casing; and (c) a valve mechanism operationally coupled with the outlet, the valve mechanism controlling a flow of the filler substance from the casing to the internal volume of the wheel such that when a pressure level in the internal volume of the wheel is below a first predefined level, the valve mechanism allows the filler substance to flow into the internal volume until the pressure level reaches a second predefined level, wherein the second predefined level is equal to, or greater than, the first predefined level.
US10543718B2 Tire comprising a layer of circumferential reinforcing elements
Tire comprising a crown reinforcement formed of at least two working crown layers each formed of reinforcing elements inserted between two skim layers of rubber compound. First layer S of polymer compound is in contact with a working crown layer and the carcass reinforcement. The crown reinforcement comprises a layer of circumferential reinforcing elements. The elastic modulus under tension at 10% elongation of a skim layer of a working crown layer is less than 8.5 MPa, the maximum value of tan(δ) of the skim layer of a working crown layer is <0.100. First layer S comprises a filled elastomer blend having a macro dispersion coefficient Z≥65 and a maximum tan(δ) value <0.100 and its complex dynamic shear modulus G*, measured at 10% and 60° C. on the return cycle is >1.35 MPa.
US10543716B1 Wheel with interchangeable caps
Systems, apparatus, devices, brackets, assemblies, and methods for a wheel hub with interchangeable caps for changing the appearance of wheels having exposed lug nuts about a center hole. A bracket invention having both a small cap and a large cap can be used on an existing wheel which exposes a center hole and the lug nuts. A smaller cap can be used to cover only the center hole of the wheel. A larger cap can be used to cover both the center hole and the exposed lug nuts on the wheel. An adapter ring can be used for OEM (original equipment manufacturer) wheels to allow for using the base that allows for either a small cap or large cap to be interchangeably used to change the exterior appearance of the wheel. The bracket can be integrated with the wheel, or be attachable onto the wheel. The caps can be mounted and dismounted by pressing and rotating spring biased emblems with either ball bearings or studs from the bases.
US10543715B2 Wheel centering sleeve
A corrosion-resistant wheel centering sleeve is provided to aid in centering a wheel about a wheel hub. The wheel centering sleeves have an adjustable thickness in order to coordinate with various-sized gap spaces in the wheel hole between the wheel and the stud.
US10543714B2 Microclimate controlled pad for effective paint stripping
An assembly for removing a desired portion of one or more layers of paint or another coating from a designated area is provided including a pad soaked with a chemical paint remover and an adhesive layer arranged about the pad configured to couple the assembly to the designated area. A removable first protective layer is positioned upwardly adjacent and is coupled to the adhesive layer. A flexible support layer is positioned adjacent the adhesive layer and the pad, opposite the removable first protective layer. A heat pad is arranged downwardly adjacent the flexible support layer. The heat pad is configured to control a microclimate adjacent the assembly when activated. A removable second protective layer is coupled to a surface of the heat pad. Removal of the second protective layer activates the heat pad.
US10543713B2 “Wideback” pamphlet for easy identification on a shelf
A pamphlet with a plurality of pages with a placard attached to the fold line of the pamphlet at a plurality of connection points by, staples. The placard attached to the fold line can be pivoted about the fold line to a position perpendicular or parallel to the pamphlet.
US10543708B2 Printing plate forming method and cylindrical forming apparatus for printing plate
A cylindrical printing plate formed with high precision and used for printing on a metal can body, particularly an aluminum or aluminum alloy can body. The forming method of a printing plate forms the printing plate to be mounted on an outer periphery of a cylindrical plate cylinder, and includes a notch forming step of forming a positioning notch in a rectangular elastic material sheet in which a resin layer to be served as a plate section is formed on one surface. A cylindrical material forming step rolls the elastic material sheet in which the positioning notch is formed and overlaps both end portions of the elastic material sheet and joining them in a cylindrical shape. A plate section engraving step engraves a printing pattern on the plate section of the elastic material sheet formed into a cylinder shape.
US10543701B2 Thermal transfer printing apparatus and thermal transfer printing method
A thermal transfer printing apparatus including a feed roll feeding an ink ribbon during forward rotation, a thermal head performing a printing process that involves thermally transferring a color material onto first printing paper using the ink ribbon fed by the feed roll, and a recovery roll winding up the used ink ribbon during forward rotation, the used ink ribbon being the ink ribbon that has been subjected to the thermal transfer. After the feed roll and the recovery roll are rotated backward to rewind the used ink ribbon onto the feed roll, the used ink ribbon is fed from the feed roll and a color material is thermally transferred by the thermal head onto second printing paper based on a disturbance pattern. Because the disturbance pattern is superimposed on a residual image remaining on the ink ribbon, it is possible to prevent leakage of the residual image.
US10543691B2 Inkjet recording apparatus
An inkjet recording apparatus includes a recording head configured to eject ink to record an image, an ink tank including an filling port for injection of the ink and configured to contain the ink to be supplied to the recording head, a cap configured to close the filling port, and a connection portion configured to connect the cap to the ink tank or a main body of the apparatus. The inkjet recording apparatus includes a rib provided adjacently to the filling port, the connection portion biases the cap in a direction separating from the filling port, and the cap removed from the filling port releases the filling port while being in contact with the rib by biasing of the connection portion.
US10543690B2 Liquid ejection apparatus
A liquid ejection apparatus includes a head that defines an individual channel including a nozzle, a feed channel communicating a reservoir and an inlet port of the individual channel, and a feedback channel communicating the reservoir and an outlet port of the individual channel. A pump assembly has at least one pump. A controller is configured to drive the pump assembly to draw air into the individual channel through the nozzle, and to drive the pump assembly to apply a pressure in the individual channel from the feed channel toward the feedback channel.
US10543689B2 Liquid discharge apparatus
A roll unit includes a feeding roller to which a belt-shaped member is wound, and a winding roller to which the belt-shaped member fed from the feeding roll is wound. One of the feeding roller and the winding roller is relatively movable to the other of the feeding roller and the winding roller.
US10543687B2 Ultrasonic maintenance cap
A maintenance cap is provided for in-situ attachment to a printhead of printing apparatus. The maintenance cap comprises a housing defining at least one chamber for receiving a liquid. An opening in the housing provides a path for the liquid to pass from the chamber into a portion of the printhead when the maintenance cap is engaged with the printhead. The maintenance cap also includes a seal disposed around the opening for engagement with the printhead. A transducer coupled to the housing is used to generate ultrasound acoustic waves in the liquid contained in the chamber and printhead so as to clean the printhead.
US10543685B2 Semiconductor device, method of manufacturing same, liquid discharge head, and liquid discharge apparatus
A semiconductor device used for a liquid discharge head is provided. The device includes a wiring layer, an insulating member formed above the wiring layer, a heat generation element arranged above and in contact with the insulating member, and electrically connected to the wiring layer, a metal member arranged above and in contact with the insulating member, and electrically connected to the wiring layer, and an electrically conductive member covering an upper surface of the metal member and electrically connected to the wiring layer through the metal member. A resistivity of the electrically conductive member is less than a resistivity of the metal member and a resistivity of the heat generation element. The heat generation element and the metal member are separated from each other.
US10543684B2 Ink jet recording device
The present invention relates to an ink-jet printing apparatus that is capable of obtaining printed materials that are free of occurrence of color migration and have good appearance even when printed on a resin printing medium using a water-based ink, and an ink-jet printing method. The present invention provides an ink-jet printing apparatus including an ink-jet printing head that ejects a water-based ink onto a resin printing medium that is transported in a feeding direction thereof, and an under heater that heats the printing medium from a rear side surface of the printing medium opposed to a front side surface thereof which faces to the ink-jet printing head, in which the under heater is disposed at a position spaced at a distance of from 0.05 to 3.0 mm apart from the rear side surface of the printing medium upon printing, and an ink-jet printing method using the ink-jet printing apparatus.
US10543683B2 Ink jet recording method and control method of ink jet recording apparatus
An ink jet recording method according to the present embodiment includes ejecting a water-based ink composition where a content of an organic solvent having a standard boiling point of 280° C. or more is 0.5% by mass or less from a head nozzle and attaching the water-based ink composition to a recording medium, in which a contact angle between at least a part of the surface of the member in contact with the water-based ink composition in the members in the head and the water-based ink composition is 30° or less, and the surface of the member in contact with the water-based ink composition is formed of a material having an SP value of 9 or less.
US10543682B2 Head unit control circuit
A head unit control circuit controls a head unit. The head unit includes an ejector, a determination circuit, and an ejection limit circuit. The ejector includes a displaceable piezoelectric element for controlling the liquid ejection. The piezoelectric element is displaced by changing a drive signal potential. The determination circuit determines whether the piezoelectric element has a predetermined electrical storage capability. The ejection limit circuit stops the drive signal to limit the ejection of the liquid based on the determination. The head unit control circuit includes: a first terminal that outputs an instruction signal instructing the head unit to execute the determination; a second terminal that outputs the drive signal; and a third terminal that is between the first terminal and the second terminal. The third terminal has a smaller potential change width than the second terminal when the ejecting section ejects the liquid.
US10543680B2 Inkjet printing apparatus and ejecting method
There is provided an inkjet printing apparatus including: a print head having an ejection opening surface on which a first ejection opening array capable of ejecting a first ink and a second ejection opening array capable of ejecting a second ink are arranged; a cap member; and a print controller configured to cause the first and the second ejection opening arrays to perform preliminary ejection to an inside of the cap member, and to cause the first ejection opening array to perform preliminary ejection in a first relative position and cause the second ejection opening array to perform preliminary ejection in a second relative position, wherein, on the cap member, a position in which the second ink lands by the preliminary ejection overlaps with an area where the first ink lands by the preliminary ejection.
US10543676B2 Image recording method, and transfer assisting liquid and liquid set used therefor
An image recording method includes a first intermediate image forming step of applying an ink onto an intermediate transfer member to form a first intermediate image, a second intermediate image forming step of applying a transfer assisting liquid containing thermoplastic resin particles and rosin-based resin particles to the first intermediate image formed on the intermediate transfer member to form a second intermediate image, and a transfer step of bringing the second intermediate image formed on the intermediate transfer member into contact with a recording medium, peeling off the second intermediate image from the intermediate transfer member while the contact state with the recording medium is maintained, and transferring the second intermediate image to the recording medium. In the transfer step, the second intermediate image brought into contact with the recording medium has a temperature not less than the glass transition temperature of the thermoplastic resin particles.
US10543675B2 Wiper blade for printer roller
A blade assembly of a waste catchment system for a roller comprises a support plate for attachment to a tray of the waste catchment system and a blade holder. The blade holder is configured to receive a blade having a free edge adapted to engage with the roller to be cleaned. The blade holder includes a channel for receiving and retaining the blade, the blade being insertable into and removable from the blade holder by sliding with respect thereto. The blade holder and the blade comprise respective co-operating elements configured to permit sliding of the blade relative to the blade holder in the longitudinal direction of the blade and to constrain the blade against movement relative to the blade in a direction perpendicular to the said longitudinal axis.
US10543674B2 Device for treating substrates
The present invention relates to a device for treating substrates which device is modular and versatile in use. The device for treating substrates comprises a feeder and one or more first sub-structure modules which each comprise a pressure cylinder with devices for fixing a lift and a sheet-conveying device and one or more second sub-structure modules which respectively have a transport cylinder with openings formed on the cover surface thereof, and having devices for fixing a lift and a sheet conveying device. All of the first or second sub-structure modules have the same intersection point for connecting the sub-structure modules on one of the inlet and the exit side and they all can be equipped with an attachment module.
US10543672B2 Additive manufacturing for an overhang
In one example, a non-transitory processor readable medium with instructions thereon that when executed cause an additive manufacturing machine to inhibit build material from coalescing in an area of a first layer of build material where a second slice of an object will overhang a first slice of the object formed in the first layer of build material.
US10543669B2 Accessory units for consumer electronic devices and related assemblies
An accessory unit includes a front flap and a rear cover. The rear cover includes a recessed portion that defines a chamber and a frame that extends about an opening of the chamber. The chamber is configured to receive a consumer electronic device, and the frame is configured to hold the consumer electronic device therein. For example, the frame may define a multi-sided cross-section with an inner edge thereof configured to engage a chamfered edge of the consumer electronic device. The front flap may include segments formed from panels with folding regions therebetween, which allow the front flap to fold. Further, an end region of the front flap hingedly couples the front flap to the rear cover, such that the front flap may be moved between open and closed configurations.
US10543666B2 Composite sandwich panel and associated methods of manufacture
Disclosed herein is a composite sandwich panel that includes a first face portion with fully consolidated comingled first fibers and a first thermoplastic matrix. The composite sandwich panel also includes a second face portion with fully consolidated comingled second fibers and a second thermoplastic matrix. Additionally, the composite sandwich panel includes at least one core portion with partially consolidated comingled third fibers and a third thermoplastic matrix. The at least one core portion is interposed between the first and second face portions. The first thermoplastic matrix is melded with the third thermoplastic matrix and the second thermoplastic matrix is melded with the third thermoplastic. A density of the fibers across a thickness of the composite panel is non-uniform.
US10543661B2 Metal foil with resin, and metal-clad laminate and circuit board using same
A metal foil with resin is a metal foil with resin including a metal foil and a resin layer disposed on the metal foil, resin layer being obtained by half-curing a resin composition. The resin composition contains a first component that is a polymer, a second component that is a polyarylene ether copolymer, and a third component that is an epoxy resin. The first component has structures represented by formulae (1) and (2) below, with no unsaturated bond between carbon atoms. The third component has two or more epoxy groups per molecule. The second component is compatible with the first component, and the third component is incompatible with the first component.In the formulae (1) and (2), a ratio between x and y is x:y=0:1 to 0.35:0.65, R1 represents hydrogen atom or methyl group, and R2 represents hydrogen atom or an alkyl group.
US10543660B2 Heat-insulation sheet, electronic device using same, and method for producing heat-insulation sheet
A heat-insulation sheet includes a first silica xerogel layer, a second silica xerogel layer, and a composite layer. The first silica xerogel layer includes a first silica xerogel, and the second silica xerogel layer includes a second silica xerogel. The composite layer is located between the first silica xerogel layer and the second silica xerogel layer, and includes at least one type of unwoven fabric fibers, and a third silica xerogel. The third silica xerogel is located in a spatial volume of the unwoven fabric fibers.
US10543659B2 Thermally expandable sheet and thermally expandable sheet production method
A thermally expandable sheet includes: a first thermally expansive layer that is formed on one side of a base and contains a first thermally expandable material and a first binder, the first thermally expansive layer having a first ratio of the first thermally expandable material with respect to the first binder; and a second thermally expansive layer that is formed on the first thermally expansive layer and contains a second thermally expandable material and a second binder, the second thermally expansive layer having a second ratio of the second thermally expandable material with respect to the second binder, wherein the second ratio is lower than the first ratio.
US10543657B2 Multilayer structures for electronic device housings
In one example, a housing for an electronic device may be disclosed which may include a first multi-layer structure. The first multi-layer structure may include a first layer and a second layer formed on the first layer. Each of the first layer and the second layer may include a plurality of protruding features and a plurality of recessing features on an edge of the first layer and the second layer. At least one of the plurality of recessing features of one layer may intersect at least one of the plurality of protruding features of other layer.
US10543656B2 Tough shrinkable films
The present disclosure relates to a shrink film comprising a polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % of terephthalic acid residues; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; and (b) a diol component comprising: (i) about 0.01 to about 30 mole % neopentyl glycol residues; (ii) about 0.01 to about less than 15 mole % 1,4-cyclohexanedimethanol residues; (iii) about 50 to 90 mole % ethylene glycol residues; and (iv) about 2 to 15 mole % total diethylene glycol residues in the final polyester composition; wherein the total mole % of the dicarboxylic acid component is 100 mole %, and wherein the total mole % of the diol component is 100 mole %.
US10543654B2 Method for producing corrugated board
An apparatus is provided for producing longitudinally corrugated product. The apparatus includes a guide roll for guiding a web of medium material, wherein at least a portion of the guide roll is adapted to be arranged at an angle relative to another portion of the guide roll. The apparatus further includes a plurality of flute forming bars oriented generally along a longitudinal axis of the web to define a first corrugating labyrinth effective to longitudinally corrugate the web to an intermediate geometry. The apparatus further includes a pair of corrugating rollers that cooperate to define, at a nip therebetween, a second corrugating labyrinth effective to longitudinally corrugate the web to a substantially final geometry. The apparatus further includes a web travel pathway for the web that follows a path around a portion of the guide roll, through the first corrugating labyrinth, and through the second corrugating labyrinth.
US10543653B2 Construction and composition of preformed containers used in a high-pressure press
A container assembly for use in a high-pressure press having a central pressure cell and a method of sealing a central pressure cell. The container assembly includes a container that receives a sample to be pressed, and a gasket distinct from the container, the gasket meeting the container at an interface. The container and the gasket are dimensioned to locate the interface within the central pressure cell.
US10543650B2 Exercise weight structure
A method of producing an exercise weight structure comprises mixing a particulate material with a binder material and molding the resulting mixture to an appropriate shape. An outer skin for the exercise weight structure is firstly formed of a resilient material, and forms a mold into which an inner weight section or body is molded or cast. The inner weight section and the outer skin are both formed of recycled material and include a common binder material.
US10543647B2 Apparatus for curing a composite part layup
A composite part layup is cured using a set of tools adapted to hold the layup and which include at least one tool face contacting the layup. Means are provided for heating the tool face to cure the part layup, and for selectively cooling sections of the tool face.
US10543643B2 Automated de-powdering via liquid immersion
According to some aspects, a de-powdering subsystem for an additive fabrication system is described. The de-powdering subsystem may comprise a bath subsystem. The bath subsystem may comprise a reservoir configured to contain a liquid and to accept objects to be de-powdered into the liquid, and an agitation facility configured to cause currents within the liquid. The agitator facility may be at least one of (i) a pump configured to circulate the liquid within the reservoir, (ii) a heating element configured to generate convection currents in the liquid, and (iii) a stirrer driven through a linkage to a motor. The bath subsystem may comprise at least one ultrasonic transducer configured to apply ultrasonic vibrations to the liquid within the reservoir.
US10543642B2 3D printer having dual stage structure
A 3D printer has a dual stage structure and includes: a frame; an extrusion unit having a nozzle configured to extrude a raw material; a stacking base unit positioned under the extrusion unit and configured to receive the raw material on a surface thereof so that an object is formed in a layer-by-layer manner on the surface; and a cutting unit positioned between the stacking base unit and the extrusion unit and configured to grind or cut the object formed on the surface of the stacking base unit, wherein the frame is configured to be connected to outer sides of the stacking base unit, the extrusion unit, and the cutting unit, the stacking base unit and the cutting unit are configured to be vertically movable along the frame, and the nozzle is configured to be movable on a plane.
US10543640B2 Additive manufacturing system having in-head fiber teasing
A head is disclosed for an additive manufacturing system. The head may include a body, and a nozzle connected to a discharge end of the body. The nozzle may be configured to discharge a composite material including a matrix and a continuous reinforcement that is at least partially coated in the matrix. The head may also include a fiber-teasing mechanism located inside the body and upstream of the nozzle.
US10543639B2 Method for manufacturing a three-dimensional object
A method for manufacturing a three dimensional object includes steps of: providing a digital description of the object as a set of voxels; sequentially creating an actual set of voxels corresponding to the digital set of voxels. At least one voxel comprises a polymer derived from: polyol and an ionic monomer. The calculated charge density of the resulting polymer is 0.01 to 0.7 mEq/g.
US10543635B2 Apparatus for molding handle-equipped container, and mold and mold unit for use in same
An apparatus for molding a handle-equipped container is provided. The apparatus has a gripping mechanism section 160a which comprises a first gripping member 161 having a pair of first chuck members 163 for grasping a preform 200, and a second gripping member 162 having a pair of second chuck members 167 for grasping a container handle 20 in association with the action of the first gripping member 161. The apparatus can simultaneously grasp a plurality of the preforms 200 and a plurality of the container handles 20 and reliably transport them to a blow molding section.
US10543634B2 Method for automatic adjustment of the travel of a stretching rod of a device for forming hollow bodies
Disclosed is a method for adjusting the travel of a stretching sliding rod that belongs to a device for forming hollow bodies made of thermoplastic material by stretch blow molding, with the stretching rod being controlled cyclically in terms of sliding from a rest position to an adjustable stretching end position by stretching the malleable wall of a hollow body, before returning to its rest position to begin a subsequent stretching cycle of another hollow body, with the method including a control step that consists in detecting whether an axial force that opposes the sliding of the stretching rod at the end of travel is above a determined upper boundary. The stretching end position is adjusted automatically by being subjected to the axial force that is detected during the control step.
US10543629B2 Method and apparatus for injection molding of plastic materials
A method for injection molding of plastic materials into a cavity of a mold by means of a molding apparatus including at least one injector having a pin valve displaceable between a fully closed position and a maximum opening position, and vice versa, in a controlled fashion in respect of its position and speed. In the opening displacement from the fully closed position to the maximum opening position, the pin valve is initially moved at a first speed and subsequently at a second speed, where the first speed is the highest opening displacement speed of the pin valve.
US10543628B2 Mold for forming a foam pad with intersecting ridges
A molded foam is provided in which even when a force in a sliding direction is applied to another member in contact with its surface, the occurrence of a shift in position relative to the other member can effectively be prevented and the occurrence of unusual noise due to rubbing between its surface and the other member can effectively be prevented. The molded foam is formed by heating expandable resin particles filled into a foaming mold. The molded foam has a plurality of first ridges arranged in one direction and a plurality of second ridges arranged in another direction and disposed so as to intersect the first ridges, the first and second ridges being provided on the surface of the molded foam.
US10543625B2 Method and device for casting a ring-shaped plastic frame in a recess of a rotor disk of a double-sided machining machine
The invention relates to a device for casting a ring-shaped plastic frame. The device includes a first mold part and a second mold part, a rotor having at least one recess, and a mold core. The mold core includes at least one casting channel configured to connect to a supply one end. The mold parts may also include at least one mold insert. The mold volume is at least partially defined by the at least one mold insert, the at least one recess of the rotor, and the mold core. The mold volume is fluidly connected to the other end of the at least one casting channel.
US10543624B2 Process for treating a reinforcing element having a flattened cross-section
A reinforcing element, having a cross section with a flattened overall shape and extending in a main direction and comprising at least one lateral edge made of a polymeric composition comprising a thermoplastic polymer, the lateral edge extending in a general direction substantially parallel to the main direction is treated by heating at least a part of the lateral edge, during which at least a part of the lateral edge is subjected to a plasma flow so as to raise the temperature of the part of the lateral edge above the melting point of the thermoplastic polymer.
US10543621B2 Active and passive self-evacuation of a self-priming water pump
A water supply apparatus for the supply of water to a machine tool, including a water pump, a water accumulator device, a suction line, a supply line and a valve device reversibly adjustable into a first and a second position. The water pump is positioned downstream of the valve device. A first connecting line, a second connecting line and a return line are provided. Here, in the first position, the first connecting line, the second connecting line and the return line are connected to one another such that water can be conveyed from the water pump, from the first connecting line, from the second connecting line, from at least a part of the suction line and from at least a part of the supply line into the return line, and, in the second position, the first connecting line, the second connecting line and the return line are not connected to one another.
US10543616B2 Wood chipper with optimized production control
A drum-type wood chipper for processing wood includes a chipper drum that is adapted to rotate about a generally horizontal drum axis, a plurality of cutting blades that are disposed around the periphery of the chipper drum, and an engine that is adapted to rotate the chipper drum about the drum axis. The wood chipper also includes a feed system that is adapted to advance wood to be processed towards the chipper drum, and a controller that is operatively connected to the engine and adapted to determine an instantaneous engine operating rate during rotation of the chipper drum. The controller is also operatively connected to the feed system and adapted to control the rate of advance of wood towards the chipper drum. The controller is also adapted to modify the rate of advance of wood towards the chipper drum as the instantaneous engine operating rate changes while the chipper drum is being rotated.
US10543615B2 Methods for making and using crown molding jig device
A method is for making a crown molding jig device. The method includes forming first and second V-shaped frames. Each of the first and second V-shaped frames has a vertex portion, and first and second legs extending from the vertex portion. The vertex portions of the first and second V-shaped frames are in a nested arrangement, and the second legs of the first and second V-shaped frames are parallel. The first legs of the first and second V-shaped frames are in a stacked arrangement, and the second legs of the first and second V-shaped frames define a recess. The first leg of the second V-shaped frame defines first and second slots. The method includes coupling first and second adjustable studs to be carried by the first leg of the first V-shaped frame, slidably receiving the coupled first and second adjustable studs into the first and second slots, respectively, so that the recess is adjustable in size, and fastening first and second fastening nuts respectively on the first and second adjustable studs.
US10543610B2 Shaving blade cartridge, a shaver comprising such shaving blade cartridge and a method of manufacturing such a shaving blade cartridge
A shaving blade cartridge includes a housing extending along a longitudinal axis having a top side, a bottom side opposite to the top side, and first and second longitudinal sides each extending longitudinally along the longitudinal axis between the top and bottom sides. A primary cutting blade is mounted on the housing between the first and second longitudinal sides, and has a cutting edge. A primary cap is located rearward of the cutting edge. A primary guard is located forward of the cutting edge. A trimming element, mounted on the housing, has a trimming edge. The trimming edge and the cutting edge are opposite one another. The primary cap is provided on a rear element, and the rear element is fitted on the housing. The trimming element is sandwiched between the housing and the primary cap.
US10543609B2 Elevated shaver
A safety razor shaves back hair of a user. An elongated back shaver handle has a grip and a blade end. A blade group has a sharp blade and a guard parallel thereto. A substrate structure is coupled to the blade end. The substrate structure is adapted to hold both the blade group and a support on a front surface with the blade group and the support spaced a distance. The blade group and the support each extend from the front surface of the substrate structure at a height sufficient to avoid loose skin of the user touching the front surface of the substrate structure. The support can be either a blunt protrusion or another blade group.
US10543608B2 Electric shaver and outer blade used in the electric shaver
An outer blade of an electric shaver has slits. Each of the slits includes: a first slit portion; a second slit portion positioned in a displaced manner from the first slit portion in a length direction of the outer blade; and a connecting slit portion connecting the first slit portion to the second slit portion. A displacement width in the length direction of the outer blade between the first slit portion and the second slit portion is set equal to or larger than at least one of widths of connecting portions of the first slit portion and the second slit portion connected to the connecting slit portion.
US10543605B2 Camera on movable arm
An electronic movement-controlled apparatus that includes a camera and a movable arm is disclosed. The movable arm has both a stationary end and a movable end with the camera being attached to the movable end so as to be movable therewith. The stationary end is configured to be coupled to a rigid support structure. The movable arm includes a plurality of arm segments connected in series to form the movable arm. The arm segments are configured to have cooperating segment regions in terms of each of the arm segments being compressible and expandable in unison to move the movable end and effect a pan and tilt movement of the camera.
US10543604B2 Failure diagnostic device and failure diagnostic method
A failure diagnostic device for performing a failure diagnosis on a multi-axis robot includes a position detector that detects a movement position of each of joint shafts included in the multi-axis robot, a torque detector that detects a disturbance torque applied to the joint shaft, a routine-operation determination circuit that determines whether or not the multi-axis robot is executing a predefined routine operation, from the movement position detected by the position detector, a reference-value calculation circuit that calculates a disturbance-torque reference value from the disturbance torque detected during execution of the routine operation, a torque correction circuit that corrects the disturbance torque detected while the multi-axis robot executes an operation different from the routine operation by using the disturbance-torque reference value, calculated by the reference-value calculation circuit, to thereby acquire a corrected disturbance torque, and a failure diagnostic circuit that performs a failure diagnosis.
US10543601B2 Workpiece conveying device
A workpiece conveying device includes a traveling platform which moves on traveling rails, a workpiece sucker arranged below the traveling platform, a vertical drive guide which is provided on the traveling platform and vertically drives the workpiece sucker, and a fork which is placed on the workpiece sucker so as to sandwich the workpiece sucker. With this structure, effects are obtained such that the workpiece conveying device is capable of achieving space saving in a factory and is capable of improving moving accuracy and increasing a moving speed while making it difficult to damage a product.
US10543598B2 Machining system with optimal paths
A method for implementing machining operations for a workpiece. Pre-existing hole locations for temporary fasteners in the workpiece requiring a clamp-up force for performing the machining operations to form holes in the workpiece is identified. A set of the pre-existing hole locations is determined from the pre-existing hole locations that results in an optimal path for performing the machining operations on the workpiece taking into account clamp-up force specifications for the workpiece. The optimal path has a near-minimum distance. An ordered sequence for performing the machining operations to form the holes at hole locations is determined that has the optimal path. Robotic control files that causes robotic devices to perform the machining operations using the optimal path is created. The robotic devices are operated using the robotic control files to form the holes in the ordered sequence using the optimal path that takes into account the clamp-up force specifications.
US10543597B1 Task assignment method for wheeled robot network
A dynamic multi-objective task allocation system within robotic networks that assigns tasks in real-time as they are detected, the system including a sensing device that detects a trigger event, the trigger event being associated with a task to be performed, and transmits a broadcast signal to a designated robotic network, the robotic network including one or more robots, the broadcast signal including information associated with the task to be performed, the trigger event, the task to be performed, and a location where the task is to be performed; and a distribution robot that receives broadcast signal from the sensing device, assigns itself a self-score associated with performing the task, transmits, to one or more receiving robots within the robotic network, a request for submission of an assessment score of each one of the one or more robots, and determines which robot is assigned to perform the task.
US10543596B2 Robot having two robot arms sharing a common upper arm
An apparatus including a robot drive, a first arm having a first upper arm, a first forearm and a first end effector, where the first end effector comprises a first and second substrate support sections and a leg located between the first and second support sections which connects the substrate support sections to a wrist joint with the first forearm, and where a connection of the leg to the wrist joint is offset unequal distances relative to respective centerlines of the first and second substrate support sections, and a second arm having a second upper arm connected to the robot drive, where the first and second upper arms are connected to a first shaft of the robot drive to be rotated in unison, and where the wrist joint does not intersect the drive axis while the first arm is being extended and retracted.
US10543593B2 Blind slide-mount fastener alignment apparatus, kit and method
A marking apparatus and its method of use facilitate blind slide-mounting of an object to a mounting surface in a desired alignment using the object as an alignment template. The apparatus includes a post element, a retention element, a tightening element and a cover. The retention element is movable against resilient bias to allow the apparatus to capture a mounting slot in the object. The resilient bias moves the retention element to a gripping position, and the cover can be rotated so as to cause the tightening element to secure the grip of the apparatus to the object. When the object is aligned with and pushed toward the mounting surface, the cover moves against an elastic bias to allow a marking end of the apparatus to contact the mounting surface so as mark the appropriate location for installation of a fastener to supportingly engage the slide-mount slot of the object.
US10543592B2 Tool stand
A tool stand provides a tool tray supported on a frame and the tool tray can be lowered on the frame for compact storage and transportation of the tool stand and tools carried by the tray. The tool stand can provide two legs or columns that support the tray and also can be folded at the top to form a bar handle. The tray can be selectable positioned in elevation on the columns. The tool stand can provide magnetic accessories such as a media viewer mount that can be advantageously positioned on the tool tray to assist the user.
US10543590B2 Reversion trigger for combustion-powered fastener-driving tool
A fastener-driving tool has a housing including a combustion chamber, where the combustion chamber generates combustion for driving a fastener, and a processor associated with the housing and in communication with the combustion chamber. The processor is configured to cause an initial combustion in the combustion chamber and cause a fastener to be driven when a first actuation event and a second actuation event occur, and is configured to cause at least one subsequent combustion in the combustion chamber and cause at least one additional fastener to be driven when only the first actuation event occurs.
US10543589B2 Method for installing a gasket into a joint between two pipes
A hammer for installing a gasket into a joint between two pipes, the hammer comprising two opposed substantially rectangular, non-square strike surfaces which are rotationally offset from one another by 90 degrees such that an appropriate substantially rectangular, non-square strike surface may be selected by the user and applied to a gasket by simply rotating the hammer in the user's hands without requiring the user to relocate around the gasket.
US10543588B2 Lighted power tool
A power tool includes a tool body including a motor having an output member that drives an accessory. A chuck is coupled for rotation with the output member relative to the tool body and configured to retain the accessory. The chuck has a chuck body that defines at least one light pipe formed therethrough. A light source disposed on a light ring coupled to the tool body and includes at least one light. Each at least one light source aligns with each of the at least one light pipe intermittently during rotation of the chuck.
US10543585B2 Wrench in the form of an open-end wrench for ratcheting increments of 30°
An open-end wrench for ratcheting increments of 30° has a short clamping jaw supported on a wrench handle so as to be pivotable about a first pivot point. A long clamping jaw is supported on the wrench handle so as to be pivotable about a second pivot point. The short clamping jaw and the long clamping jaw are each pressed into a clamping position by a spring load and can be pivoted into a receiving position against the spring load. In the clamping position, the short clamping jaw and the long clamping jaw reach around a hexagonal object. To pivot into the receiving position, the short clamping jaw is pressed against a sliding surface of the long clamping jaw by the spring load. In the clamping position, an opening width the clamping jaws is more than 55% of the distance between two opposite lateral edges of the hexagonal object.
US10543583B2 Grinding tool and manufacturing method therefor
The object of the present invention is to provide a grinding tool capable of continuing machining in a dry state and of being manufactured in a short time and at low cost, and a manufacturing method therefor. For said purpose, a grinding tool (10-1) for grinding a workpiece includes a threaded helical groove (12) formed on an outer circumferential surface of a cylindrical metal head portion (10b), ridgetop surfaces that result from the formation of the helical groove (12) and are formed so as to protrude with a trapezoidal cross-sectional shape, and abrasive grain surfaces (18) formed by winding an insulating resin rope in the helical groove (12) to mask the inside of the helical groove (12) and fixing abrasive grains on the ridgetop surfaces. A helix angle of the helical groove (12) with respect to an axial direction of the grinding tool (10-1) is set to be at least 80° and less than 90°.
US10543579B2 Polishing apparatuses and polishing methods
Some embodiments include an apparatus having a polishing mechanism configured to polish a surface of a wafer. The polishing mechanism converts fresh slurry to used slurry during a polishing process. At least one emitter is configured to direct electromagnetic radiation onto or through the used slurry. At least one detector is configured to detect transmittance of the electromagnetic radiation through the used slurry or reflection of the electromagnetic radiation from the used slurry. An identification system is coupled with the at least one detector and is configured to identify a property of the used slurry indicating that an endpoint of the polishing process has been reached. Control circuitry is coupled with the identification system and is configured to stop the polishing process based on receiving a trigger from the identification system. Some embodiments include polishing methods.
US10543577B2 Systems, methods, and apparatus for forming optical articles, and optical articles formed by the same
Optical articles and methods of manufacturing the same are disclosed herein. In one aspect, the methods and optical articles formed include light-blocking compositions applied to optical substrates in accordance with the optical properties of the optical substrate. In another aspect, a method is disclosed in which the light-absorbing compositions are printed onto the optical substrate in the shape and size of the final lens that is to be formed from the optical substrate. In another aspect, the methods and optical articles utilize at least two different light-blocking compositions to achieve desired functionality of the optical article.
US10543576B2 Glass substrate support apparatuses and methods of providing flexible glass substrate support
A glass substrate support system includes a first and second vacuum members extending lengthwise in a glass substrate feed direction along opposing edges of a flexible glass substrate. Each vacuum member has a vacuum body including a pressure chamber located therein and a support surface having a vacuum opening extending therethrough and in communication with the pressure chamber. A support rod assembly is provided that includes a plurality of support rods located between the first second vacuum members in the glass substrate feed direction. The support rod assembly has an out-of-plane configuration that supports the flexible glass substrate in a downward arc orientation.
US10543568B2 Laser processing head including circulation path for circulating coolant
A laser processing head able to prevent leakage of a coolant out of a flow path or a coolant supply pipe. The laser processing head includes a closed-circulation path that circulates the coolant for removing the heat generated in the laser processing head due to a laser beam propagating in the laser processing head, and a coolant circulation device that allows the coolant to flow in the circulation path and circulates the coolant in the circulation path.
US10543557B2 Welding torch and device using said torch
A welding torch includes a main body and an end portion suited to be fed through the main body with a welding wire and a shielding gas. The end portion includes a welding unit electrically powered and provided with an internal channel for the passage of the welding wire. A conveyor element is provided with an outlet mouth to allow the welding wire to move out of the welding unit and to allow the shielding gas to be conveyed outside of the welding unit. Electrical insulation means are interposed between the welding unit and the conveyor element with an insulation portion made of an electrically non-conductive material. The welding torch includes the conveyor channel suited to convey the shielding gas from the main body to the outlet mouth of the conveyor element. The conveyor channel is delimited at least partially by the insulation portion.
US10543550B2 Pressure welding device and pressure welding method
A pressure welding method and a pressure welding device (1) are provided. The pressure welding device (1) includes a plastification device (7), an upsetting device (8) and component mountings (34,35,36,37) for the components (2,3,3′,4) to be welded together and a machine frame (12). The pressure welding device (1) further includes a plurality of machine heads (13,14), each having a component mount (34,35), which machine heads are movably arranged on the machine frame and are connected to respective upsetting drives (22). The machine heads (13,14) and respective upsetting drives (22) can be independently driven. An upsetting head or support head (27), which is preferably secured on the frame, is arranged between the machine heads (13,14).
US10543549B2 Additive manufacturing system for joining and surface overlay
An additive manufacturing system includes an additive manufacturing tool configured to receive a plurality of metallic anchoring materials and to supply a plurality of droplets to a part, and a controller configured to independently control the composition, formation, and application of each droplet to the plurality of droplets to the part. The plurality of droplets is configured to build up the part. Each droplet of the plurality of droplets includes at least one metallic anchoring material of the plurality of metallic anchoring materials.
US10543548B2 Apparatuses and methods for induction heating
A heating apparatus for induction heating is disclosed. The heating apparatus may comprise a bearing ring, at least one bearing element disposed in the bearing ring, and a braze material adjacent to the at least one bearing element and the bearing ring. The heating apparatus may additionally comprise an inductor positioned radially adjacent to at least a portion of the bearing ring. A current source may be electrically coupled to the inductor. A bearing orienting member may also abut a surface of the at least one bearing element. The bearing orienting member may orient a surface of the at least one bearing element. A heating method is also disclosed.
US10543547B2 Low-profile mechanical retention
An assembly of mechanical components includes a solder joint between two metal components. A mounted component is retained on one side of a support structure by a solder joint on the other side of the support structure between a retainer and a connector that is fast with the mounted component and extends through the support structure. The retainer is of sheet metal construction, so that a height of the solder joint is no more than the thickness of the retainer, thus providing a low-profile joint. The assembly may be in the form of a movable push button for control of an electronic device.
US10543545B2 Method of initializing multiferroic element
A method of initializing a multiferroic element for obtaining a stable element operation includes applying at least one selected from a group consisting of an electric field and a magnetic field to the multiferroic element under a temperature condition equal to or higher than a phase transition temperature. The multiferroic element has a laminated structural body including a first alloy layer and a second alloy layer. The first alloy layer is formed by using any of antimony-tellurium, bismuth-tellurium and bismuth-selenium as a principal component. The second alloy layer is laminated on the first alloy layer, and formed by using a compound represented by the following general formula (1) as a principal component. The second alloy layer is configured to undergo phase transition between a reset phase and a set phase. Electric polarization is not caused in the reset phase, but caused in the set phase. The second alloy layer undergoes the phase transition from the reset phase to the set phase at the phase transition temperature.[Chemical Formula 1] M1-xTex   (1) Here, in the above-mentioned general formula (1), M represents an atom of any of germanium, aluminum and silicon, and x represents a numerical value of 0.5 or more and lower than 1.
US10543540B2 Power tool
A spindle of a drilling tool includes a socket portion having a first axial length (a1) of a first diameter (d1) for receiving and attaching a drill bit to the spindle. The spindle includes a fluid conduit having a second diameter (d2) narrower than (d1) for conveying a fluid to the socket portion. An interface space with diameter (d1) is formed between the fluid conduit and the drill bit when the drill bit is installed in the socket portion. A fluid conveyor, having a third diameter (d3) narrower than (d1), connects the fluid conduit to the drill bit to avoid fluid gathering in a periphery of the interface space. The fluid conveyor includes a first O-ring abutting a mouth of the fluid conduit, a second O-ring abutting a mouth of a fluid channel of the drill bit, and a spring between the first and second O-rings.
US10543538B2 Expansion sleeves and associated chucks
In one aspect, expansion sleeves for pressure-activated tool holder apparatus are described herein. An expansion sleeve, for example, comprises a first end, a second end and a longitudinal axis extending between the first end and the second end. A first set of fluid chambers are proximate the first end of the sleeve and a second set of fluid chambers are proximate the second end, wherein fluid channels extend along the longitudinal axis to connect radially offset fluid chambers of the first and second sets.
US10543536B2 Method for fabricating metal nanoparticles
The present specification relates to a method for fabricating metal nanoparticles.
US10543535B2 Method for producing powder metal compositions for wear and temperature resistance applications
A powder metal composition for high wear and temperature applications is made by atomizing a melted iron based alloy including 3.0 to 7.0 wt. % carbon; 10.0 to 25.0 wt. % chromium; 1.0 to 5.0 wt. % tungsten; 3.5 to 7.0 wt. % vanadium; 1.0 to 5.0 wt. % molybdenum; not greater than 0.5 wt. % oxygen; and at least 40.0 wt. % iron. The high carbon content reduces the solubility of oxygen in the melt and thus lowers the oxygen content to a level below which would cause the carbide-forming elements to oxidize during atomization. The powder metal composition includes metal carbides in an amount of at least 15 vol. %. The microhardness of the powder metal composition increases with increasing amounts of carbon and is typically about 800 to 1,500 Hv50.
US10543533B2 Hybrid shape memory effect elements for facile integration to structures
There is disclosed a method for chemically bonding TiNi materials to Nitinol constructs, comprising placing a Nitinol construct within a mold and packing a powder combination comprising Ti powder and Ni powder, and powder comprised of zero or more of the elements Cu, Hf, Zr, Pt, Pd, Au, Cd, Ag, Nb, Ta, O, N, B, and H, into the mold. The method further includes initiating a process of self-propagating high temperature synthesis of the powder combination within the mold to create a chemical bond between the Nitinol construct and a resulting TiNi foam to thereby create a Nitinol and TiNi assembly.
US10543531B2 Porous aluminum sintered material and method of producing porous aluminum sintered material
A porous aluminum sintered material is provided. The porous aluminum sintered material includes aluminum substrates sintered each other, wherein pillar-shaped protrusions projecting toward an outside are formed on outer surfaces of the aluminum substrates, the porous aluminum sintered material has junctions in which the aluminum substrates are bonded each other through the pillar-shaped protrusions, the junctions include a Ti—Al compound, and a eutectic alloy phase including Al and Si is provided on surface layers of the junctions.
US10543527B2 Continuous steel casting method
Conditions for soft reduction are determined in a method of continuous casting in accordance with a method utilizing the thickness of a slab strand to prevent center segregation from occurring in the strand due to an insufficient pressing rate or internal cracks from occurring in the strand due to an excessively high pressing rate.
US10543525B2 Method of verifying that self-piercing rivet gun is normal to workpieces
A method of verifying that a robot carried self-piercing rivet gun system is set-up so that workpieces that are to be riveted will be normal to a self-piercing rivet gun of the robot carried self-piercing rivet gun system during riveting includes utilizing a perpendicularity sensor to verify that the workpieces will be normal to the self-piercing gun during riveting.
US10543524B2 Thread rolling tool
A thread rolling tool for rolling or repairing a thread has a tool body, a profiled roller, and at least one counter roller. The profiled roller and the at least one counter roller are mounted on the tool body. Preferably, at least one of the profiled roller and the at least one counter roller is mounted so that it is axially displaceable. The profiled roller has a profiled roller profile that has a pitch.
US10543521B2 Press forming method and vehicle component
Disclosed is a press forming method press forming a workpiece between a die and a punch, while pushing the punch into the die by means of a relative motion of the die and the punch, the method includes: producing an intermediate molding (100B) having ridges (100d) formed in predetermined parts of the workpiece, and then press forming the intermediate molding (100B) into a final shape, to thereby substantially thicken and work-harden the predetermined parts of the workpiece.
US10543517B2 Particle for treatment and repairing of soil contamination and repairing method
A particle for treatment and repair of soil contamination is mainly composed of potassium ferrate and an inorganic cementitious material. The inorganic cementitious material is a powdery air-hardening or hydraulicity inorganic cementitious material. The potassium ferrate and the inorganic cementitious material are mixed according to the mass fraction of 1:5-50. After mixing is carried out, the particle with the particle diameter ranging from 2 mm to 5 mm is formed by means of vibration of a vibration screen, the particle is wrapped by a water-soluble film, and the water-soluble film is heated to be shrunk and then is closely attached to the outer surface of the particle. Also disclosed is a method for repairing soil by using the particle. When the particle is mixed with an ozone water solution is adopted.
US10543513B1 Commingling optimization of mail
A processing system and method for nationwide commingling of mail items to increase efficiency and lower mailing costs includes a pre-sort facility which creates a first set of diverted mail items and a first set of associated data while a print and mail manufacture facility generates a second set of manufactured mail items and a second set of associated data and then receives the first set of diverted mail items and first set of associated data from the pre-sort facility and then commingles the first and second sets of mail items according to a predetermined set of commingling rules applied to the first and second sets of associated data to produce commingled mail items which reduces postal costs in mailing the commingled mail item.
US10543509B2 Nanotube material having conductive deposits to increase conductivity
An apparatus having a conductive body defined by a plurality of nanotubes forming a planar structure. The apparatus further includes a plurality of junctions, formed by adjacent nanotubes, and a plurality of conductive deposits positioned at the junctions to electrically join the adjacent nanotubes at the junctions and reduce electrical resistance between the nanotubes, thereby increasing overall conductivity of the body.
US10543504B2 Microfluidic system with single drive signal for multiple nozzles
A microfluidic die is disclosed that includes a plurality of heaters above a substrate, a plurality of chambers and nozzles above the heaters, a plurality of first contacts coupled to the heaters, and a plurality of second contacts coupled to the heaters. The plurality of second contacts are coupled to each other and coupled to ground. The die includes a plurality of contact pads, a first signal line coupled to the plurality of second contacts and to a first one of the plurality of contact pads, and a plurality of second signal lines, each second signal line being coupled to one of the plurality of first contacts, groups of the second signal lines being coupled together to drive a group of the plurality of heaters with a single signal, each group of the second signal lines being coupled to a remaining one of the plurality of contact pads.
US10543499B1 Disposable powder-dispensing bulb
The disposable powder-dispensing bulb is configured for use with talcum powder. The disposable powder-dispensing bulb stores the talcum powder. The disposable powder-dispensing bulb dispenses the talcum powder. The disposable powder-dispensing bulb is disposable. The disposable powder-dispensing bulb is degradable after disposal. The disposable powder-dispensing bulb comprises a degradable bulb, a degradable cap, and talcum powder. The degradable bulb is a hollow containment structure. The talcum powder is stored in the degradable bulb. The degradable cap attaches to the degradable bulb. The degradable cap opens and closes to provide access to the talcum powder stored within the degradable bulb.
US10543495B2 Modular spray dryer system
A spray drying system for drying liquid into powder including a plurality of processing towers each including an elongated drying chamber, a spray nozzle assembly at an upper end of the drying chamber and a powder collection chamber at a lower end of the drying chamber. The powder collection chamber of each processing tower being configured to discharge power to a common conveyor system.
US10543489B2 Delumper and method of delumping edible material
A delumper includes a housing defining a chamber in which edible material is received. The housing includes a screen having a plurality of holes and a plurality of inwardly extending fingers. The holes are sized such that edible material of a first diameter is capable of passing through the holes and edible material of a second, larger diameter is incapable of passing through the holes. The fingers are arranged in at least a first row, and the first row is located at or between a 5:00 position and a 7:30 position. The delumper further includes a rotatable shaft including a plurality of paddles spaced along a length of the shaft. When the shaft rotates, each of the paddles passes between adjacent fingers of the first row such that edible material located within the chamber is forced into contact with the fingers and cleaved by the paddles.
US10543487B2 Jaw crusher, crushing plant and crushing method
A jaw crusher including a fixed jaw and a movable jaw for forming a crushing chamber therebetween which is open at the top, the fixed jaw including a first wear part mounted thereto and the movable jaw including a pitman and a second wear part mounted thereto. The crushing chamber includes an upper section, a middle section, and a lower section having equal heights (h). The pitman is bearing-mounted to an eccentric shaft and to at least one slide member. The at least one slide member is configured to slide in a direction substantially perpendicular to the vertical diagonal of the crushing chamber. A method for crushing mineral material in a jaw crusher or a crushing plant is also disclosed.
US10543485B2 Slip chip device and methods
A device is described having a first surface having a plurality of first areas and a second surface having a plurality of second areas. The first surface and the second surface are opposed to one another and can move relative to each other from at least a first position where none of the plurality of first areas, having a first substance, are exposed to plurality of second areas, having a second substance, to a second position. When in the second position, the plurality of first and second areas, and therefore the first and second substances, are exposed to one another. The device may further include a series of ducts in communication with a plurality of first second areas to allow for a substance to be disposed in, or upon, the plurality of second areas when in the first position.
US10543480B2 Methods of preparing a catalyst utilizing hydrated reagents
A pre-catalyst composition comprising a) a silica support comprising silica wherein an amount of silica ranges from about 70 wt. % to about 95 wt. % based upon a total weight of the silica support, b) a chromium-containing compound wherein an amount of chromium ranges from about 0.1 wt. % to about 5 wt. % based upon the amount of silica, c) a titanium-containing compound wherein an amount of titanium ranges from about 0.1 wt. % to about 20 wt. % based upon the amount of silica, d) a carboxylic acid wherein an equivalent molar ratio of titanium-containing compound to carboxylic acid ranges from about 1:1 to about 1:10, and e) a nitrogen-containing compound with a molecular formula containing at least one nitrogen atom wherein an equivalent molar ratio of titanium-containing compound to nitrogen-containing compound ranges from about 1:0.5 to about 1:10.
US10543478B2 Catalyst for oxidative dehydrogenation and method of preparing the same
The present invention relates to a method of preparing a catalyst for oxidative dehydrogenation. More particularly, the method of preparing a catalyst for oxidative dehydrogenation includes a first step of preparing an aqueous iron-metal precursor solution by dissolving a trivalent cation iron (Fe) precursor and a divalent cation metal (A) precursor in distilled water; a second step of obtaining a slurry of an iron-metal oxide by reacting the aqueous iron-metal precursor solution with ammonia water in a coprecipitation bath to form an iron-metal oxide (step b) and then filtering the iron-metal oxide; and a third step of heating the iron-metal oxide slurry.In accordance with the present invention, a metal oxide catalyst, as a catalyst for oxidative dehydrogenation, having a high spinel phase structure proportion may be economically prepared by a simple process.
US10543473B2 Controlling local fluid age in a stirred reactor
In a stirred tank chemical reactor the mean age of the reactor contents affects a number of properties of the product, including for example the homogeneity of the product. The mean average age of the reactor contents can be determined by constructing a transparent model of the reactor and filling it with a fluid containing a fluorescent dye and having flow properties comparable to those of the reactor in use. A light is shone on the fluid as it is stirred under reaction conditions and a clear fluid flow into the model. Pictures are taken of the reactor contents and the mean fluid age of the contents of the model are determined relative to the exit age of the contents. This approach can be applied to determine for example which reactor ports to use, what agitator to use, what flow rates to use to improve reactor function.
US10543472B2 Method of encapsulating particulate material
A method of encapsulating particulate materials that enables the particulate materials to be used in end use applications where they currently are not useful. The method uses specific sol gel technology to encapsulate solid particles. In addition, the method can be used to multiple coat a coated particle.
US10543470B2 Reactors and methods for processes involving partial oxidation reactions
Described herein are improved chemical reactors for carrying out partial oxidation reactions. The chemical reactor permits the use of levels of oxygen above the lower explosion limit (LEL) typically used in partial oxidation reactions, which increases both volumetric reactivity and conversion per pass, resulting in reduced separation and reactant recycle costs. Also described are methods of using the reactors.
US10543463B2 Homogeneous cation-exchange composite membrane having excellent chemical resistance and method for producing the same
The present invention provides a cation-exchange composite membrane comprising a copolymer containing a styrene repeating unit introduced with a sulfonation group, a tert-butylstyrene repeating unit and a crosslink repeating unit, an olefin additive, a plasticizer and a polyvinyl halide polymer. The cation-exchange composite membrane comprising a copolymer containing a styrene repeating unit introduced with a sulfonation group, a tert-butylstyrene repeating unit and a crosslink repeating unit, an olefin additive, a plasticizer and a polyvinyl halide polymer of the present invention not only displays low electrical resistance, excellent ion exchange capability, excellent ionic conductivity, excellent mechanical properties, excellent chemical properties, and processability, but also is easy to regulate its ion exchange ability and ionic conductivity. Also, the composite membrane of the invention is easier to produce and cheaper to manufacture than the conventional cation-exchange composite membrane.
US10543462B2 Hollow fiber carbon molecular sieve membranes and method of manufacturing using radial-flow pyrolysis
One or more polymeric hollow fiber membranes are pyrolyzed to form one or more hollow fiber CMS membranes by directing a flow of pyrolysis gas through a bundle of polymeric membranes (including a plurality of green, polymeric hollow fiber membranes oriented so that their ends are disposed with ends of the bundle) in a direction perpendicular to a length direction of the bundle in order to sweep away off-gases that are formed during pyrolysis.
US10543457B2 Isolated plasma array treatment systems
Systems, methods, and apparatus are contemplated in which a tube cell that produces a dielectric barrier discharge (DBD) is individually configured to minimize the mixing of unwanted byproducts of the generated plasma with an exhaust air stream. The tube cell generates a DBD within a tube cell, such that oxidants or radicals are generated in an environment substantially separated from the exhaust stream. The generated oxidants are directed to intersect with the exhaust stream to minimize the generation of unwanted byproducts. The tube cells are further shaped and arranged in tube cell arrays to alter the flow dynamics of the exhaust stream and the oxidant or radical streams, including mixing of the streams.
US10543456B2 Method for separating components using solids producing multi-stage direct and indirect-contact exchange
A process for forming a solid product or products is disclosed. The process is provided with n desublimating exchangers. An exchanger E1 being associated with a first exchanger and an exchanger En being associated with an nth exchanger, n representing the number of exchangers. The n exchangers comprise at least one direct-contact exchanger comprising a contact fluid. A process fluid is passed through the n exchangers in order from E1 through En. The process fluid comprises a product component or components. The solid product or products form from the product component or components in the plurality of exchangers by desublimation. The solid product or products are separated from the process fluid. In this manner, a solid product or products is formed.
US10543454B2 Carbon dioxide absorbent
The present invention provides a carbon dioxide absorbent comprising a primary amine and a dialkylene glycol dialkyl ether or trialkylene glycol dialkyl ether. The carbon dioxide absorbent according to the present invention has an excellent carbon dioxide absorptivity, absorption rate and regeneration property.
US10543453B2 Removal of sulfate from solvent solutions using an anion exchange resin
Generally, the present invention relates to the selective removal of divalent sulfur oxyanions (e.g., sulfate) from an aqueous solvent using an anion exchange resin. More particularly, this invention relates to regenerative processes for the selective removal and recovery of sulfur dioxide from a source gas using an aqueous absorption medium in which an anion exchange resin is used to selectively remove divalent sulfur oxyanion impurities accumulating in the recirculating aqueous absorption medium.
US10543451B2 Ammonia-adding system for ammonia-based desulfurization device
Ammonia-adding apparatus and methods for ammonia-based desulfurization use multi-stage control, calculate a theoretical amount of ammonia based on gas amounts provided by an inlet continuous emission monitoring system (CEMS) and an outlet CEMS of the ammonia-based desulfurization device or associated gas amounts, a SO2 concentration provided by the inlet CEMS, and a predetermined SO2 concentration of the outlet CEMS. The apparatus and methods calculate a corrected theoretical amount of ammonia using half of the ratio of the actual amount of added ammonia to the actual amount of removed sulfur dioxide as a correction coefficient for the theoretical amount of ammonia; add an ammonia absorbent equivalent to the corrected theoretical amount of ammonia to the ammonia-based desulfurization device through an ammonia metering means and an ammonia control valve, and automatically control the actual ammonia flow rate based on the actual SO2 concentration and a change trend provided by the outlet CEMS.
US10543449B2 Silencer, exhaust valve, valve device, air dryer, compressed air supply device for vehicle, and compressed air supply system
An air dryer includes a supporting base, a drying agent container, and an outer cover. The supporting base includes an inlet for receiving compressed air to be subject to a drying process and an outlet for delivering the processed compressed air that has undergone the drying process. The drying agent container is a container supported on the supporting base, contains a drying agent in the interior, and enables the drying process to be performed by passing the compressed air from the inlet through the drying agent. The outer cover surrounds the outer side of the drying agent container on the supporting base and defines a chamber for storing the compressed air between itself and the drying agent container. The supporting base includes first and second mounting surfaces, which are oriented in different directions, and a plurality of inlets, which are oriented in different directions and receive the compressed air.
US10543448B2 Agglomeration-resistant desulfurizing product
Disclosed herein is an agglomeration-resistant desulfurizing product for removing contaminants from a fluid stream. The agglomeration-resistant desulfurizing product comprising a metal oxide composition for reacting with contaminants and a polymeric crystallization inhibitor for reducing the agglomeration of the desulfurizing product resulting from using the desulfurizing product. A method to produce the agglomeration-resistant desulfurizing product and a method to treat a fluid stream is also disclosed.
US10543446B2 Honeycomb structure
A honeycomb structure including prismatic columnar honeycomb segments and a bonding layer, wherein the bonding layer has rows in each of which bonding layer portions each disposed between two honeycomb segments arranged to face each other are arranged to extend from one point of a peripheral edge of a bonded body of the honeycomb segments to the other point thereof, in a cross section, the bonding layer of each of the-rows is disposed so that among the bonding layer portions arranged in one direction, an outermost circumference bonding layer portion and at least one of the other bonding layer portions are not superimposed on each other on an extension line of the one direction, and a ratio of shift of side surfaces of adjacent honeycomb segments to a length of one side of a side surface of honeycomb segments having the same cross-sectional shape is 10% or less.
US10543443B2 Air intake system for engines
A method for operating an air intake system for an engine is disclosed. The air intake system includes an air filter configured to provide filtered air to the engine for combustion. The method includes activating a blower, by a controller, to generate suction and draw purged contaminants from the air filter for facilitating a purging of the air filter. The method further includes deactivating the blower, by the controller, upon a determination of a completion of the purging of the air filter.
US10543442B2 Multiple stage rotating coalescer devices
Disclosed are multiple stage rotating coalescer devices comprising a first stage and a second stage. The first stage may include a rotating coalescing element comprising coalescing media. The second stage is positioned either upstream or downstream or the first stage. The second stage may include one of: (i) a rotating cone stack separator, or (ii) a separate rotating coalescing element comprising coalescing media.
US10543438B1 Skimming apparatus
A skimming apparatus with a pivot arm and a drive follower on the pivot arm that guides a belting to facilitate precise placement of the belting for efficient skimming.
US10543436B2 Filter assembly including an attachment member for a removable filter cartridge
A filter assembly includes a canister housing closable by a lid and containing a removable and replaceable filter element cartridge. The lid is part of the filter element cartridge and a single unitary component therewith, such that removal of the filter element cartridge also removes the lid, and replacement of the filter element cartridge also replaces the lid.
US10543435B2 Low-energy dynamic filter
A means to exploit the Dean Vortices for dynamic filtering on a macro scale intended for application in utility and industrial processes is disclosed. This method relies on an apparatus of computed construction to optimize the centripetal force and minimize the effect of gravity on the separation and effectiveness of the Dean Vortices. The method is also supported by an apparatus of construction which results in an optimized elliptical flow channel that enhances the formation and persistence of the Dean Vortices.
US10543431B2 Spinning top toy
A spinning top toy includes a braking member, a shaft part which is configured to be rotated, and a body which is detachably attached to the shaft part. The body is configured to be detached from the shaft part by being rotated with respect to the shaft part. When an impact is applied to the body, the braking member is configured on one of the shaft part and the body and is movable by a centrifugal force. When urged by the centrifugal force, the braking member is configured to become in contact with the other of the shaft part and the body.
US10543428B2 Video game processing apparatus and video game processing program product
A video game processing apparatus is provided for controlling progress of a video game while displaying a player character on a display screen of a display device provided with a touch panel. The video game processing apparatus is provided with a virtual controller information memory for storing virtual controller information on a virtual controller. The display device is caused to display the virtual controller on the display screen on the basis of the virtual controller information. In a case where an operational input to the virtual controller displayed on the display screen is received, the video game processing apparatus updates a shape of the virtual controller on the basis of the virtual controller information, and controls an action of the player character on the basis of the received operational input. The operational input may include a slide operation and a tap operation, for example.
US10543425B2 Systems and methods for detecting and displaying a boundary associated with player movement
Systems and methods for indicating that a boundary is crossed during execution of a video game are described. One of the methods includes generating, by a camera, a field-of-view, the field-of-view encompassing a plurality of boundaries that define a volume. The method further includes capturing, by the camera, one or more images of a head-mounted display (HMD) within the field-of-view. The method includes identifying, by a processor, a position of the HMD in a real-world environment from the one or more images. The method includes determining, by the processor, whether the HMD at the position has crossed one of the boundaries. The method includes generating one or more video frames including a guard rail upon determining that the HMD has crossed the one of the boundaries and sending the one or more video frames to the HMD for display.
US10543421B1 Game using a dodecahedron
The philosophy of games is to provide a mental challenge to the person who is playing the game. With this game a person can build the game according to that person's wants and desires and in this case a dodecahedron is used; the dodecahedron is color coded and an interior sphere is placed with the dodecahedron. Clues that have been placed in pockets of the outside surface of the dodecahedron will consist of locations where coins are hidden. These coins will be gathered and the dodecahedron is manipulated. The interior sphere contains the solution to the game or a prize and is initially locked prior to the start of the game. As the contestants play the game and “solve” the puzzle, the interior sphere is unlocked and the solution or prize is revealed. The game can be structured to the desires of the individual builder as often as possible.
US10543418B1 Climbing skin attachment apparatus, methods, and systems
One aspect of this disclosure is a climbing skin attachment apparatus. The apparatus may comprise a climbing skin attachment portion and a snow device connection portion, a channel extending at least partially through the climbing skin attachment portion along a channel axis to receive an anchor portion of a climbing skin, and a passage extending through the climbing skin attachment portion and into the channel along the channel axis to receive a lead portion of the climbing skin. Related apparatus, methods, and systems also are described.
US10543412B2 Apparatus and method of play for a golf chipping game
Disclosed is a golf chipping game and methods of play for a golf chipping game. The golf chipping game includes an inclined playing surface having a plurality of holes defined therein; an impact absorbent material comprising or affixed to the playing surface; and a chipping mat disposable a distance from the playing surface.
US10543403B2 Golf balls having foam center and thermoset outer core layer with hardness gradients
Multi-layered golf balls containing a dual-core structure are provided. The core structure includes an inner core (center) comprising a foam composition, preferably foamed polyurethane. The outer core layer is preferably formed from a non-foamed thermoset composition such as polybutadiene rubber. The core layers have different hardness and specific gravity levels. The specific gravity (density) of the foam inner core is preferably less than the density of the outer core layer. The core assembly preferably has a positive hardness gradient extending across the entire assembly. The core structure and resulting ball have relatively good resiliency.
US10543395B2 Offsetting treadmill deck weight during operation
A treadmill includes a deck, an incline mechanism attached to the deck, and a lift assist mechanism that offloads a portion of the lifting force from the incline mechanism when the incline mechanism changes an elevation of a portion of the deck.
US10543393B2 Suspension trainer
A suspension trainer including a handle system comprised of a ring element and a removable strap element.
US10543390B2 Method to assist with using a seating device, and electronic object carrying out said associated method and system
The invention relates to a method to assist with using a pendula seating device, said device comprising a spherical foot, a seating portion, a body being secured at a first end to said foot and at a second end to the seating portion and a position-measurement sensor being secured to said device. The invention also relates to a remote electronic object carrying out said method by the processing unit thereof, the remote electronic object also comprising output means and means ensuring communication with said seating device. Said electrical object also comprises a memory of programs comprising instructions of a computer program product the execution or interpretation of which by the processing unit causes the implementation of the assistance method.
US10543388B2 Exercise systems including weight clusters composed of weight pods, and components of such systems
Exercise systems that include self-coupling weight pods that couple with one another to form weight clusters that a user can use in performing various body movements, such as exercise and conditioning movements. Each weight pod typically has a calibrated weight so that the user may know the amount of weight they are using. Each weight pod includes one or more coupling features that allow that weight pod to couple to one or more other weight pods and/or to an accessory, such as a strap. In some embodiments, each weight pod is soft so as to inhibit injury to a user of another close by the user. The weight pods can be used with one or more accessories, such as a strap, a bell bag that emulates a kettle bell, and a rucksack that can be configured to be a multifunctional component of an overall exercise system, among others.
US10543384B2 Hair styling compositions having shear thickening properties
The present disclosure relates to a hair styling compositions that exhibit non-Newtonian shear thickening behavior. The hair styling composition include: (a) about 0.1 to about 7 wt. % of AMP-acrylates/allyl methacrylate copolymer, based on the total weight of the hair styling composition; (b) one or more nonionic film-forming polymers; (c) one or more polysaccharides; (d) one or more nonionic surfactants; and (e) water. Additional components such as, for example, water-soluble solvents, fatty compounds, amphoteric film-forming polymers, volatile or non-volatile silicones, thickeners (ionic or non-ionic), etc., may also optionally be included. The hair styling compositions are particularly useful for styling or shaping hair and for providing hold, discipline, and texture to hair.
US10543374B2 Connector assemblies with bending limiters for electrical stimulation systems and methods of making and using same
A connector assembly includes an elongated connector housing defining a port at the second end of the connector housing for receiving a proximal end of a lead or lead extension; a lumen that extends from the port along at least a portion of the length of the connector housing; connector contacts axially spaced-apart and disposed along the lumen; and non-conductive spacers disposed between adjacent connector contacts, at least one of the non-conductive spacers includes a first region. One or more additional features are included to resist bending of the connector assembly. One such feature is a non-conductive first insert disposed between adjacent connector contacts to maintains a minimum distance between the adjacent connector contacts. Another feature is a stiffening element disposed within apertures in the spacers and connecting two or more of the spacers. Yet another feature is a stiffening sleeve disposed within the housing.
US10543368B2 Seizure onset classification and stimulation parameter selection
A neurostimulation system senses electrographic signals from the brain of a patient, extracts features from the electrographic signals, and when the extracted features satisfy certain criteria, detects a neurological event type. A mapping function relates the detected neurological event type to a stimulation parameter subspace and a default stimulation parameter set where the values of the stimulation parameters define an instance of stimulation therapy for the patient. The decision whether to implement a stimulation parameter subspace or a default stimulation parameter set may be informed by integrating other information about a state of the patient. A stimulation parameter subspace or stimulation parameter set may optimized by testing it against various thresholds until certain effectiveness criteria is satisfied. The neurological event type may be one of several electrographic seizure onset types.
US10543360B2 Lead fixation accessory, lead stabilization tool, and related procedures
A lead fixation accessory configured to be positioned over a skull hole and to transition between an opened state and a closed state during a lead implant procedure protects against lead migration by providing a mechanism for securing the lead in place at the skull hole while a stylet is removed from the lead. The lead fixation accessory remains in place after the implant procedure to provide chronic lead stability. A lead stabilization tool configured to access and grip a lead through a slotted cannula during the lead implant procedure also protects against lead migration by providing a mechanism for securing the lead in place at a point where the lead exits the skull hole while the slotted cannula is removed from the skull hole and peeled away from the lead.
US10543356B2 Pain sensory nerve stimulation apparatus
A pain sensory nerve stimulation apparatus includes: an electrode portion including: a first electrode, a tip end of which is adapted to be inserted into a skin; and at lease one second electrode which is disposed in a circumference of the first electrode without being electrically conductive with the first electrode, and which is adapted to be in contact with a skin; and a stimulation signal supplying unit, supplying a bipolar stimulation signal between the first electrode and the second electrode, the bipolar stimulation signal including a first waveform signal and a second waveform, the first waveform which is convex in a negative direction in the first electrode, the second waveform signal which is convex in a positive direction in the first electrode.
US10543355B2 Medical push connectors
Medical push connectors and systems are provided. A medical push connector can include an engagement member operatively coupled to a release member. The engagement member may releasably couple a medical device to the medical push connector. Medical push connector systems may include one or more medical devices and a medical push connector coupled to, or coupleable to, the one or more medical devices.
US10543350B2 Port septum with integral valve
A septum for a port is provided, the septum having a top wall and a side wall. The side wall can include a pressure-activated valve element for regulating the flow of fluid across the valve. The curvature of the side wall and the geometry of the sidewall and the housing can be tailored to bias the valve element to open at different pressures during infusion and aspiration. The side wall can also include an extended portion that can function as a suture wing for securing the port within a port pocket.
US10543348B2 Method of enhancing absorption of ingested medicaments for treatment of an an ailment of the GI tract
A method of using a vibrating gastrointestinal capsule in coordination with an ingestible medicament for treatment of an ailment of the GI tract. The vibrating gastrointestinal capsule, is provided to the subject, and includes: a housing; a vibrating agitation mechanism causing the housing to exert vibrations on an environment thereof; a power supply for powering said vibrating agitation mechanism; and a control mechanism for activating said vibrating agitation mechanism to operate in said vibration mode of operation. The subject ingests the ingestible medicament and the vibrating gastrointestinal capsule. At least one of a time of ingesting of the vibrating gastrointestinal capsule and a timing or activation delay of the vibration mode of operation is controlled, such that the vibration mode of operation at least partially transpires or completely transpires within an actual or estimated absorption time period of the ingestible medicament within the gastrointestinal tract of the subject.
US10543346B2 Drug delivery systems and methods for treatment of bladder cancer
Methods, devices, and medicaments that include oxaliplatin are provided for use in the treatment of bladder cancer by locally administering oxaliplatin into the bladder of a patient to achieve a sustained concentration of oxaliplatin in urine in the bladder sufficient to produce a therapeutic concentration of oxaliplatin in bladder tissue. The oxaliplatin may be delivered into the bladder from an intravesical drug delivery device inserted into the bladder, wherein the device continuously releases the oxaliplatin into the urine in the bladder over an extended period of hours or days.
US10543345B2 Fluid delivery device with positionable tube
A fluid delivery device includes a tube coupled to an axial manipulator. The axial manipulator includes an elongate member arranged to move axially in a housing. The tube is in fluid communication with a fluid diverter which is arranged to move axially in the housing upon axial movement of the elongate member. Seals are provided to prevent fluid from leaking out of the housing. A fluid port is in fluid communication with the tube via the fluid diverter, such that fluid can flow in and out of the tube via the fluid port and the fluid diverter.
US10543344B2 Double-ended wire guide and method of use thereof
The present invention generally relates to double-ended wire guides for use in a percutaneous procedure within a body cavity and to methods of using such devices. In certain embodiments, the wire guide includes a break-away discontinuity near at least one end of the wire guide.
US10543341B2 Safety catheter with passive release
A safety intravenous catheter that includes a passive release feature. The catheter assembly includes ready, safe, and released positions. In the release position, a retainer being in a proximal retainer position relative to a collar enables release of the catheter hub from the catheter insertion device. The sharp tip of the insertion needle remains inaccessible in the release position in order to prevent unwanted needle sticks.
US10543336B2 Nitric oxide reactor and distributor apparatus and method
A reaction and distribution system may include a distributor securable near or in a path correspond to a breathing passage such as the nostrils or the mouth of a user for delivering nitric oxide therapy thereto. The distributor may contain an internal reactor for creating the nitric oxide from reactants. Alternative embodiments may include an inhaler for delivering nitric oxide into the mouth of a user. The inhaler may contain a reaction chamber monolithic or contiguous with the inhaler for creating the nitric oxide from reactants.
US10543334B2 Apparatus and method for detecting liquid level in a clear or partially clear container
A trap bowl is provided to accumulate liquid droplets from a filter, as a liquid content. The trap bowl includes a transparent vertical prism. The transparent vertical prism includes a face that forms a vertical transparent surface facing against a content of the section. The face can provide a first angle of total reflection when content of the section is a type of gas, and a second angle of total reflection when the content of the section is the liquid content. A light source may emit a light beam incident on the face at an angle of incidence. The angle of incidence results in reflection of the light beam, striking the light receiver, when the face has the first angle of total reflection, and results in refraction of the light beam, missing the light receiver, when the face has the second angle of total reflection.
US10543328B1 Integrated diagnostic and therapeutic PAP system
The present invention relates to an integrated sleep diagnosis and treatment device, and more particularly to an integrated apnea diagnosis and treatment device. The present invention additionally relates to methods of sleep diagnosis and treatment. The sleep disorder treatment system of the present invention can use a diagnosis device to perform various forms of analysis to determine or diagnose a subject's sleeping disorder or symptoms of a subject's sleep disorder, and using this analysis or diagnosis can with or in some embodiments without human intervention treat the subject either physically or chemically to improve the sleeping disorder or the symptoms of the sleeping disorder. The diagnostic part of the system can use many different types of sensors and methods for diagnosing the severity of the symptoms of or the sleep disorder itself. The treatment part of the system can use a device to physically or chemically treat the subject's symptoms or sleep disorder itself.
US10543327B2 Methods and systems for adaptive base flow
This disclosure describes systems and methods for providing novel adaptive base flow scheduling during ventilation of a patient to optimize the accuracy of estimated exhaled tidal volume. Further, this disclosure describes systems and methods for providing novel adaptive inspiratory trigger threshold scheduling during the novel adaptive base flow scheduling.
US10543321B2 Pen cap
The present invention refers to a pen cap, being capable of covering a distal end of a drug delivery device comprising at least one protruding element located inside the pen cap which prevents that the rim of an outer needle cap, while being a protective casing for the needle at the distal end of the drug delivery device, can get stuck within a part of the pen cap if the user puts the pen cap on the drug delivery device. The inner diameter of the pen cap is reduced by means of the at least one protruding element, such that the inner diameter of the pen cap is smaller than the largest outer diameter of the outer needle cap. Furthermore, the invention relates to a drug delivery device comprising a pen cap with the described protruding elements.
US10543320B2 Drive assembly for a drug delivery and drug delivery device
A drive assembly for a drug delivery device is provided, including a piston rod which is moveable in a distal direction in order to deliver a dose of medication, and including a drive element which is configured to cause a movement of the piston rod. The drive assembly further includes a decelerating mechanism which is configured to decelerate the movement of the drive element such that the movement of the piston rod is decelerated during the dispense of a dose. The decelerating mechanism includes a decelerating element which is fixed with respect to a housing of the drug delivery device at least during the dispense of a dose and the drive element, wherein the drive element is configured to rotate with respect to the housing during the dispense of a dose, and wherein the decelerating element and the drive element rub against each other during the dispense of a dose.
US10543316B2 Injector with adjustable dosing
An injector for injecting a medicament in a patient. The injector includes a container comprising a fluid chamber containing a first volume of a medicament, and an injection conduit associated with the fluid chamber for defining a fluid pathway therefrom to inject the medicament from the fluid chamber through the injection conduit to an injection location. The injector also includes a firing mechanism associated with the fluid chamber for expelling the medicament from the fluid chamber through the injection conduit, and a volume-control mechanism operable to control a fraction of the first volume of medicament that is injected when the firing mechanism is actuated to inject the medicament.
US10543314B2 Personalized parameter modeling with signal calibration based on historical data
Medical devices and related patient management systems and parameter modeling methods are provided. An exemplary method involves obtaining, by a computing device, historical measurements of a condition in a body of the patient previously provided by a sensing device, obtaining, by the computing device, historical operational context information associated with preceding operation of one or more of an infusion device and the sensing device, obtaining, by the computing device, historical values for a parameter from one or more of the infusion device and the sensing device, determining, by the computing device a patient-specific model of the parameter based on relationships between the historical measurements, the historical operational context information and the historical values, and providing, by the computing device via a network, the patient-specific model to one of the infusion device, the sensing device or a client device.
US10543313B2 Glucose level control system with offline control based on preceding periods of online control
Apparatus and methods calculate and deliver doses of insulin and optionally glucagon into a subject. Online operation controls delivery of correction doses of insulin automatically in response to regular glucose measurements from a sensor, and offline operation calculates and delivers correction doses based on isolated glucose measurements and information gathered autonomously during preceding online operation. In another aspect, offline operation includes automatically calculating and administering meal doses based on information gathered autonomously during preceding periods of online operation. Both methods include generating relevant control parameters tailored to the individual and continually converged upon and potentially modulated during online operation. The control parameters are employed in real time during periods of offline operation to regulate glucose level without the need for user-provided control parameters such as correction factors and insulin-to-carbohydrate ratios.
US10543312B2 Fluid delivery system and method of fluid delivery to a patient
A fluid delivery system includes a pressurizing mechanism. The pressurizing mechanism includes: a substantially cylindrical body having a movable member positioned therein that divides the body into a first chamber and a second chamber; a plunger rod connected to a first side of the movable member and extending through a substantially closed first end of the body; and an elongated member connected to a second side of the movable member and extending through a substantially closed second end of the body. The plunger rod configured to operatively engage a fluid container. Fluid is dispensed from the fluid container by forming a vacuum within at least the first chamber by moving the movable member toward the second end of the body, allowing atmospheric pressure to enter the second chamber, and actuating the pressurizing mechanism to cause the moving member to move towards the first end of the body.
US10543306B2 Apparatus for making extracorporeal blood circulation available
An apparatus for providing an extracorporeal blood circuit control includes a base module having a control device and a patient module releasably connected to the base module and having blood-conducting components of the extracorporeal blood circuit. A pivot system is also provided at the base module and at the patient module to pivot the patient module relative to the base module about a horizontal axis.
US10543304B2 Blood treatment apparatus with multiple axis monitor mount
Extracorporeal blood treatment apparatus (10) having a monitor (20) mounted on a multiple axis monitor mount (30) are described herein along with methods of rotating the monitor about multiple axes (31, 33). In one or more embodiments, the monitor mount is water resistant to facilitate cleaning of the blood treatment apparatus.
US10543303B2 Batteries for use in implantable medical devices
Multi-cell battery packs can be made safer with certain features that mitigate the consequences of cell failure. Parameters of a cell are monitored to determine when the cell should be disconnected from the pack in case of a fault. The battery is reconfigured to continue operating in a safer mode. An over-charging prevention system reduces the maximum voltage that remaining battery pack can be charged to, so that the cells do not overcharge. Additional circuitry allows the disconnected cell to be periodically reconnected to the battery pack to determine if its conditions have sufficiently improved. The cells also include components for self-powering these cell functions while it is disconnected from the rest of the circuit.
US10543299B2 Surface coatings
Described herein are substrate coatings.
US10543298B2 Salts of tetracyclines
A tetracycline salt comprising a tetracycline and an organic acid wherein the organic acid is oxalic acid or maleic acid is provided. The tetracycline is preferably doxycycline, minocycline, sancycline, lymecycline, tetracycline or demeclocycline, and preferred salts include oxycycline maleate, minocycline oxalate, tetracycline oxalate, demeclocycline maleate, demeclocycline oxalate, sancycline maleate, lymecycline maleate, or lymecycline oxalate. A pharmaceutical formulation comprising a tetracycline salt according to the invention is also provided, as is a medical device having coated thereon a salt or pharmaceutical formulation according to the invention. A salt of the invention, or a formulation of the invention are also provided for use as medicaments, particularly for use in the treatment or prevention of an inflammation and/or an infection. There is also provided a method of preparing a tetracycline salt, which method comprises reacting a tetracycline base with an excess of an organic acid in a solvent.
US10543297B2 Diffusion-hardened medical implant
A composition and medical implant made therefrom, the composition including a thick diffusion hardened zone, and preferably further including a ceramic layer. Also provided are orthopedic implants made from the composition, methods of making the composition, and methods of making orthopedic implants from the composition.
US10543294B2 Compositions and methods for treating bone defects
A bone graft composition includes a biologically-resorbable cement and a plurality of processed bone particles, where each of the bone particles have a shape configured to interconnect with adjacent bone particles. A method for treating a bone defect using the bone graft compositions includes providing the bone graft composition and administering an effective amount of the bone graft composition to a site of a bone defect in a subject. Kits including a biologically-resorbable cement powder and a plurality of processed bone particles are also provided.
US10543288B2 Modified-dextrans for use in optical glucose assays
The invention is directed to a competitive glucose binding affinity assay comprising a glucose receptor (typically mannan binding lectin) labeled with an assay fluorophore and a modified glucose analog (typically dextran) labeled with a reference fluorophore. In certain embodiments, the glucose analog is dextran and is coupled to both a reference fluorophore and a quencher dye (e.g. hexamethoxy crystalviolet-1). Optionally the reference fluorophore is blue shifted relative to the assay fluorophore.
US10543287B2 Immune-compromised zebrafish
Genetically-modified zebrafish lacking one or more immune-related genes, and the use thereof, e.g., in cell or tissue transplantation methods or in stem cell biology. In a first aspect, the invention provides a genetically-modified fish whose genome is homozygous for engineered or induced genetic alteration, e.g., an alteration that changes the sequence of the genomic ONA resulting in insertion and deletion of nucleotides that disrupt protein function or shift the frame of translation leading to premature protein termination, in one or more immune-related genes selected from the group consisting of: foxn1, rag2, jak3, prkdc, and interleukin 2-receptor gamma a and (IL2RGa and IL2RGb), wherein the genetic alteration results in an inactivation (i.e., loss of expression or function) of both alleles of the immune-related gene.
US10543285B2 Compositions and methods for targeted delivery of therapeutic and/or diagnostic agents
In one aspect, methods of targeted nanoparticle and cell delivery are described herein. In some embodiments, methods described herein comprise coupling nanoparticles and cells to a carrier cell to form a nanoparticle-cell conjugate or cell-cell conjugate, disposing the nanoparticle-cell or cell-cell conjugate in a biological environment, and delivering the nanoparticles and cells to target cells or tissues located within the biological environment. The nanoparticles comprise a biodegradable photoluminescent polymer, and the nanoparticle-cell conjugate is formed using one or more click chemistry reaction products.
US10543283B2 Intranasal administration of guanidinylated aminoglycosides
This disclosure relates to intranasal administration of conjugates comprising guanidinylated aminoglycosides (“guanidinoglycosides”) and a polypeptide (e.g., an enzyme, antibody, or polypeptide growth factor). For example, such administration methods are useful for delivering a polypeptide to the brain and/or cerebrospinal fluid. Such methods are useful for treating a lysosomal storage disease through intranasal administration of a conjugate comprising one or more guanidinoglycosides and an enzyme useful for treating a lysosomal storage disease.
US10543282B2 Targeted peptide conjugates
The present invention relates to the preparation and use of therapeutic compounds for the treatment of diseases at specific subcellular target areas such as specific cellular organelles. In particular, the therapeutic compounds of the invention are specific for modifying enzyme activity within targeted organelles or structures of cells and tissues. Subcellular organelles and structures that may be specifically targeted by compounds of the present invention include lysosomes, autophagasomes, the endoplasmic reticulum, the Golgi complex, peroxisomes, the nucleus, membranes and the mitochondria.
US10543281B2 Pharmaceutical composition containing camptothecin polymer derivative
Provided is a pharmaceutical preparation including a polymerized camptothecin derivative that is obtained by bonding a camptothecin derivative having nanoparticle-forming properties by associating in an aqueous solution, to a polymer carrier, the pharmaceutical preparation composition having enhanced preparation stability. Particularly, a pharmaceutical preparation maintaining nanoparticle-forming properties and camptothecin derivative bonding stability, which are important factors, and having excellent storage stability is provided. Disclosed is a pharmaceutical preparation including a block copolymer in which a polyethylene glycol segment is linked to a polyglutamic acid segment including a glutamic acid unit having a camptothecin derivative bonded thereto; and a saccharide. The pharmaceutical preparation forms associates in an aqueous solution, and the ratio of change in the scattered light intensity of the associates of the pharmaceutical preparation obtained after the pharmaceutical preparation is stored for 4 weeks at 40° C. under light-shielded conditions, is 20% or less.
US10543273B2 Anti-fibroblastic fluorochemical emulsion therapies
The present invention is directed to compositions and methods targeting tissue resident cells, such as fibroblasts, in a subject harboring conditions or at risk for conditions that would benefit from anti-fibroblastic therapy. The present invention relates to the use of fluorochemical compositions and methods of delivery that result in retention of the fluorochemical composition and any bioactive agent delivered in combination with the fluorochemical composition.
US10543270B2 Methods of treating wounds in a diabetic subject
The present disclosure provides a method of treating wound healing in a subject, the method comprising administering to the subject a compound that inhibits VEGF-B signalling.
US10543266B2 Polysaccharide vaccine formulations and processes for industrial production of bacterial polysaccharides
The present invention relates to the field of combined vaccine compositions which are effective against all forms of meningococcal diseases as well as typhoid fever. The vaccine formulations comprising antigens from capsular polysaccharides of Neisseria meningitidis A, Neisseria meningitidis C, Neisseria meningitidis Y, Neisseria meningitidis W135, Neisseria meningitidis X, Salmonella typhi Vi capsular polysaccharide (ViPs) or capsular ViPs conjugated to a carrier protein tetanus toxoid (ViPs-TT). This invention is also related to improved methods, especially the use of an improved feed media and an improved method of downstream processing and industrial purification of capsular polysaccharides. The vaccine is free of any animal component or alcohol and is in absolute compliance with respect to the religious sentiments of various ethnic groups. The composition is highly effective and stable, yet cost-effective and affordable, especially for lower-middle income and low-income countries.
US10543263B2 Compositions and methods for treating cancer with anti-CD22 immunotherapy
Chimeric antigen receptors (CARs) containing CD22 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the CARs are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making CAR T cells are also disclosed.
US10543259B2 Methods and compositions for the identification and treatment of individuals having or likely to develop short stature
The instant disclosure relates to methods useful for the treatment or prevention of progressive growth failure in a subject in need thereof. The method may include the step of administering a PAPPA2 gene product to the subject. Also disclosed is the identification of a novel gene mutation that may be used as a marker to identify subjects particularly suited for such treatment. Compositions containing a therapeutically effective amount of PAPPA2 protein and a pharmaceutically acceptable carrier are also disclosed.
US10543251B2 Flagellin related polypeptides and uses thereof
The use of flagellin and flagellin related polypeptide for the protection of mammals from the effects of apoptosis is described.
US10543249B2 Pharmaceutical composition for a sustained release of lanreotide
A pharmaceutical composition for a sustained release of peptide therapeutics, in particular for a sustained release compatible with therapeutic treatments of at least two months. In an embodiment, the composition comprises lanreotide as an active agent, a hydrosoluble co-solvent, and water with the pH of the composition being from 4.0 to 7.5.
US10543247B2 Aloe preparation for skin enhancement
Methods for providing skin enhancement and pain relief to an individual in need of treatment by administering to such an individual an effective amount of an immunostimulatory Aloe vera derived composition. Oral and topical methods and compositions are provided. Aloe vera derived immunostimulatory compositions and methods of producing such compositions are provided.
US10543246B2 Composition for preventing or treating hyperlipidemia
A method for preventing or treating hyperlipidemia includes administrating a composition consisting of a Salvia miltiorrhiza extract, a Crataegus pinnatifida extract, a Polygonum multiflorum extract, and a Ligusticum chuanxiong extract to a subject in need thereof. The composition may reduce an amounts of serum cholesterol and LDL-cholesterol and increase an amount of HDL-cholesterol, significantly reduce an amount of serum triglyceride compared with existing statin-based drugs, thereby exhibiting prophylactic and therapeutic effects of hyperlipidemia with various symptoms even without the co-administration of other drugs; and reduce an amounts of hepatic to cholesterol and triglyceride, thereby exhibiting an effect of inhibiting fatty liver.
US10543242B2 Composition for the treatment of joint conditions
The present invention relates to a composition for improving the health status of various joints in the human body. The composition includes at least one plant extract as fatty base with active role, at least one extract from plants with anti-microbial properties, at least one extract from plants with analgesic and/or anti-inflammatory properties, and at least one extract from plants with anti-rheumatic and regenerative properties, to which dimethylsulfoxide, allantoin and/or potassium alum may be added. The composition may be used to treat osteoarthritis, rheumatic joint disease, joint swelling, pain, hallux valgus, traumatic conditions of the joints including sprains, strains, post-surgical recovery, bone edema, and speed up the recovery of athletes post-injury.
US10543241B2 Methods and materials for reducing multiple risk factors associated with the metabolic syndrome
Provided are processes of reducing and/or eliminating risk factors associated with metabolic syndrome in a subject through the administration of a nelumbo extract. The nelumbo extract supplement is administered orally, intravenously, or subcutaneously. In one aspect, a daily dose of 10-1,000 mg of the extract supplement is administered to the subject for a period of 6 weeks to 6 months.
US10543238B2 Compositions comprising bacterial strains
Provided are compositions comprising a bacterial strain of the genus Blautia, for use in a method of increasing the microbiota diversity and/or inducing stability of the microbiota of a subject.
US10543237B2 Bioeffective krill oil compositions
This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical CO2 or CO2 plus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical CO2 in combination with approximately 20% ethanol. The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.
US10543235B2 Pericytes are intermediate progenitors for epicardial derived coronary artery smooth muscle
Methods and compositions are provided for regenerating smooth muscle tissue by the provision of a purified population of epicardial-derived pericytes, where the smooth muscle tissue may comprise, without limitation, coronary artery tissue; kidney tissue, etc. Compositions and kits for practicing the methods and/or for use with the systems of the disclosure are also provided.
US10543233B2 Drug resistant immunotherapy for treatment of a cancer
The present disclosure is generally related to methods for combining chemotherapy and immunotherapy for the treatment of a cancer. The methods also relate to generating a drug-resistant cytotoxic immune cell line and uses thereof in conjunction with cytotoxic drugs.
US10543226B2 Methods and compositions for treating cancers and enhancing therapeutic immunity by selectively reducing immunomodulatory M2 monocytes
The present disclosure provides pharmaceutical compositions comprising nucleic acids capable of targeting IGF-1R expression in M2 cells. The present disclosure also provides methods for the selective reduction of M2 cells by targeting expression of IGF-1R in these cells. The present disclosure further provides methods for treating cancer and enhancing therapeutic by targeting expression of IGF-1R in M2 cells in patients. The pharmaceutical composition of the present invention is effective when administered systemically to subjects in need thereof. The ease of administration of the pharmaceutical composition facilitates treatment and enhances patient compliance.
US10543222B2 Therapy for inhibition of single-stranded RNA virus replication
Pharmaceutical compositions showing the ability to inhibit or suppress replication of a filovirus in an individual are disclosed. The disclosed compositions are useful for treating, reventing, or reducing the spread of infections by filovirus. A method includes administering at least one agent of the present disclosure to an individual infected with or exposed to a filovirus, wherein the step of administering is carried out for a suitable time period so that the individual is treated; and determining whether the individual has been treated, wherein the step of determining includes one of measuring an inhibition in viral replication, measuring a decrease in viral load, or reducing at least one symptom associated with the filovirus.
US10543217B2 Method of treating frailty
Disclosed is a method of treatment or prevention of frailty in an elderly patient, particularly having an age of 60 or older. The method provides the concomitant parenteral administration of a combination of an anabolic steroid and a vitamin D compound. A preferred combination comprises nandrolone decanoate and cholecalciferol (vitamin D3). The invention, in a further preference, provides a booster therapy to support frail elderly that have undergone hospitalization or surgery to retain independence and regain their regular physical and mental activities.
US10543214B2 Compositions and methods of use of cis-4-[2-{[(3S,4R)-3-fluorooxan-4-yl]amino}-8-(2,4,6-trichloroanilino)-9H-purin-9-yl]-1-methylcyclohexane-1-carboxamide
Provided are formulations and dosage forms of cis-4-[2-{[(3S,4R)-3-fluorooxan-4-yl]amino}-8-(2,4,6-trichloroanilino)-9H-purin-9-yl]-1-methylcyclohexane-1-carboxamide, alternatively named (1s,4s)-4-(2-(((3S,4R)-3-fluorotetrahydro-2H-pyran-4-yl)amino)-8-((2,4,6-trichlorophenyl)amino)-9H-purin-9-yl)-1-methylcyclohexane-1-carboxamide, or a pharmaceutically acceptable salt, tautomer, solvate, hydrate, co-crystal, clathrate, or polymorph thereof.
US10543213B2 Treatment of relapsed and/or refractory solid tumors and non-hodgkin's lymphomas
Methods are provided for the treatment of relapsed and/or refractory solid tumors (including neuroendocrine carcinomas (NEC)) and non-Hodgkin's lymphomas (NHLs) and the like, using substituted heterocyclic derivative compounds and pharmaceutical compositions comprising compounds useful for the inhibition of lysine specific demethylase-1 (LSD-1).
US10543205B2 Oral delivery vehicle containing nicotine
The invention relates an oral delivery vehicle tablet containing nicotine, the delivery vehicle tablet being formed by compression of a plurality of particles, the oral delivery vehicle tablet comprising nicotine, the oral delivery vehicle tablet comprising sugar alcohol(s) in an amount of 40 to 100% by weight of the delivery vehicle tablet, wherein at least 10% by weight of the delivery vehicle tablet comprises a plurality of particles consisting of erythritol and wherein the delivery vehicle tablet comprises a plurality of further sugar alcohol particles in an amount of at least 10% by weight of the delivery vehicle tablet, wherein said further sugar alcohol particles comprise at least one sugar alcohol and wherein said further sugar alcohols particles have a composition which is different from said particles consisting of erythritol.
US10543202B2 Topical nifedipine formulations and uses thereof
The present application relates to topical formulations in the form of an oil-in-water emulsion comprising nifedipine and a photostabilizing effective amount of quercetin or a photostabilizing effective amount of a combination of quercetin and butyl methoxydibenzoylmethane (BMDBM). Such topical formulations may, for example, be used for the treatment of diseases, disorders or conditions that benefit from topical administration of nifedipine such as but not limited to Raynaud phenomenon, chilblains or wound healing.
US10543200B2 Compositions and methods for drug sensitization of parasites
Compositions and methods for inhibiting and/or sensitizing or re-sensitizing a parasite to an antiparasitic drug are provided. The compositions can comprise a an arylphenoxypropionate derivative, an aryloxyphenoxyacetate derivative, an aryloxyphenylacetate derivative, one or more substituted quinols, or a pharmaceutically acceptable salt, hydrate, or prodrug thereof, or a combination thereof in an amount and formulation sufficient to sensitize the parasite to the drug, treating infection of a patient by a parasite with a drug, or to prevent symptomatic infection of a patient by a parasite with a drug.
US10543199B2 Macrocycle and composition comprising thereof
A macrocycle represented by formula (I) and a pharmaceutical composition comprising the macrocycle, or a crystalline form, pharmaceutically acceptable salt, hydrate or solvent compound, stereoisomer, prodrug, or isotopic variant of the macrocycle. The macrocycle and the composition thereof inhibit a protein kinase.
US10543194B2 Organic compounds
The present invention relates to certain PDE2 inhibitory compounds, in free or salt form, pharmaceutical compositions containing such compounds and methods for the treatment of PDE2 mediated disorders.
US10543188B2 Tiglien-3-one derivatives
The present invention relates to tiglien-3-one compounds and their use in methods of treating or preventing protozoal infections, bacterial infections, parasitic infections and cell proliferative disorders. The tiglien-3-one compounds are also used in methods of controlling pests in humans, animals, plants and the environment.
US10543185B2 Method for treating idiopathic pulmonary fibrosis
Aspects of the disclosure relate to a method for treating idiopathic pulmonary fibrosis (IPF) in a patient with N-acetylcysteine (NAC) comprising administering NAC to a patient after a sample from the patient has been genotyped and determined to be any one of: a) homozygous or heterozygous for a thymine at the single nucleotide polymorphism rs3750920; b) homozygous or heterozygous for guanine at the single nucleotide polymorphism rs5743894; or c) homozygous or heterozygous for thymine at the single nucleotide polymorphism rs35705950.
US10543184B2 Method to treat functional somatic syndromes with combination of aciclovir and celecoxib
The present invention relates to pharmaceutical compositions comprising a combination of a therapeutically-effective amount of the antiviral compound aciclovir and a therapeutically-effective amount of the COX-2 inhibitor celecoxib. The invention is further related to methods of treating functional somatic syndromes by administering a therapeutically-effective combination of aciclovir and celecoxib.
US10543178B2 Dosage forms and related therapies
This invention is directed in part to novel doses, dosage formulations, and routes of administration of such doses and dose formulations, said dose and dose formulations containing one or more copper chelators, for example, one or more trientine active agents, including trientine analogues, trientine salts, trientine prodrugs, and trientine derivatives, useful in the treatment of diseases, disorders and conditions, including in indications where copper may play a role.
US10543176B2 Topical formulation for binding to dermatological cannabinoid receptors
A topical cream or ointment is provided that provides for the binding to CB1 and/or CB2 receptors for the soothing of dermatological itching. The cream or ointment composition provides the effect of cannabinoids without the actual use of cannabinoids. Several essential oils, including Black Pepper, Ylang Ylang, and Melissa essential oils in combination, contain caryophyllene, a sesquiterpene, in effective amounts to bind to the CB2 receptor and help reduce an urge to itch the skin.
US10543174B2 Modified release tablet composition comprising mirabegron
The present invention relates to a pharmaceutical composition, particularly a modified release tablet composition comprising mirabegron or a pharmaceutically acceptable salt thereof and to a process for preparing such a composition.
US10543171B2 Dermal drug delivery using amphiphilic dendron-coil micelles
The invention generally relates to the field of drug delivery. In particular, the invention relates to amphiphilic dendron-coils, micelles thereof and their use for the transdermal delivery of drugs.
US10543166B2 Implantable drug delivery devices and methods of making the same
A drug delivery device is provided that includes a device body, a number of solid, compressed drug tablets, and a retention frame. The device body includes a drug reservoir lumen and a retention frame lumen. The number of solid, compressed drug tablets are positioned in the drug reservoir lumen, and the retention frame is positioned in the retention frame lumen. The drug tablets may be mini-tablets aligned in the drug reservoir lumen, with an interstice formed between any two adjacent drug tablets facilitating deformation of the device body. Systems and method are also provided for loading a drug delivery device. In one embodiment, the method includes positioning one or more solid drug units upstream of the drug delivery device; and driving the drug units into the drug delivery device with a flow of pressurized gas.
US10543162B2 Kojic acid polymers
A controlled release system for kojic acid having improved stability has been identified. To minimize degradation, kojic acid was incorporated into a hydrolytically degradable polymer (e.g., a polycarbonate-ester)). By synthesizing polymer precursors containing kojic acid-linker-kojic acid chemical structures, versatile monomers were developed that can be used to modulate polymer properties. Additionally the synthetic method lends itself to the development of other polymer systems. Polymers having one or more groups that will yield kojic acid upon degradation of the polymer backbone, as well as methods of use thereof are described.
US10543161B1 Methods for protecting and improving the appearance of skin
The present disclosure relates to methods for protecting skin from UV radiation while simultaneously improving the appearance of skin. The methods include layered application of a skin perfecting composition and a sunscreen composition. The skin perfecting composition comprises: (i) about 1 to about 40 wt. % of at least one primary film forming polymer having a Young's modulus of 0.1 to 50 MPa, and elongation at break >50% and a glass transition temperature of <0° C.; (ii) about 1 to about 35 wt. % of at least one pressure sensitive adhesive polymer; (iii) about 1 to about 35 wt. % of soft focus powder; and (iv) water. The sunscreen composition comprises: (i) at least one organic UV filter; and (ii) a cosmetically acceptable carrier.
US10543160B2 Cosmetic composition including water soluble scrub particles containing polypeptide and/or cell culture
The present invention relates to a non-aqueous cosmetic composition comprising water-soluble scrub particles containing a polypeptide or a cell culture component. More specifically, the present invention relates to a non-aqueous cosmetic composition comprising 0.01 wt % to 15 wt % of hard and angulated water-soluble scrub particles containing cell culture components or various polypeptides including a peptide and an oligopeptide. Further, the cosmetic composition of the present invention provides a non-aqueous cosmetic composition which does not comprise active ingredients, but comprises water-soluble excipient scrub particles for maintaining or improving a scrubbing effect and adjusting viscosity or volume.
US10543155B2 Compositions containing zinc salts and isothiocyanates for reduction of oral volatile sulfur compounds (VSCs)
Combinations of a zinc salt and an isothiocyanate are provided, and more particularly to a consumer acceptable oral composition containing such combination which is effective in the reduction of volatile sulfur compounds (VSCs).
US10543153B2 Cosmetics made in one or more colours by applying a magnetic field, and method for their preparation
The present invention relates to a cosmetic product having a visible pattern consisting of one or more colours, comprising a cosmetic composition including one or more dyes and/or pigments which contain magnetic or magnetisable particles, characterised in that said cosmetic composition is housed in a container enclosing a magnet capable of generating a magnetic field, whereby said dyes and/or pigments are positioned and/or oriented in the container by said magnetic field, thereby creating the visible pattern.
US10543152B1 Method and apparatus for providing prescription verification
A system, apparatus, and method for providing an auditing feature capable of verifying a prescription has been correctly dispensed by a pharmacy are disclosed. More particularly, embodiments of the present invention relate to a system, apparatus, and/or method for automatically checking a customer's prescription information against known information related to the customer and/or the prescription contents in order to verify that the dispensed prescription is correct. It follows that an attentive and accurate dispensing process may be made available for a pharmacy to dispense prescriptions.