最新美国发明专利第2019-03-26期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US10240206B2	Biomarkers and methods for predicting benefit of adjuvant chemotherapy Biomarkers, methods, assays, and kits are provided for predicting the efficacy of adjuvant chemotherapy (ACT) in a subject with early-stage non-small cell lung cancer (NSCLC).
US10240205B2	Methods for assessing risk of developing a viral disease using a genetic test This document provides methods and materials related to treating a disease. For example, this document provides methods for treating a subject's disease based on identifying the risk of progressive multifocal leukoencephalopathy PML using a genetic test.
US10240204B2	Methods for profiling and quantitating cell-free RNA The invention generally relates to methods for assessing the health of a tissue by characterizing circulating nucleic acids in a biological sample. According to certain embodiments, methods for assessing the health of a tissue include the steps of detecting a sample level of RNA in a biological sample, comparing the sample level of RNA to a reference level of RNA specific to the tissue, determining whether a difference exists between the sample level and the reference level, and characterizing the tissue as abnormal if a difference is detected.
US10240203B2	miRNA 320a as biomarker for inflammatory bowel disease The present invention relates to an in vitro method for diagnosing an acute or relapsing phase of inflammatory bowel disease as well as a method for treating the acute or relapsing phase of inflammatory bowel disease. In addition, the present invention relates to a medicament for use in the treatment of inflammatory bowel disease. Further comprised by the present invention is the use of a nucleic acid molecule of SEQ ID NO: 1 or 2 for monitoring the progression of said disease and in vitro diagnosis of an acute or relapsing phase of said disease. Also a device for the diagnosis of said disease and kits for performing the method of the present invention are envisaged by the present invention.
US10240200B2	Methods for profiling and quantitating cell-free RNA The invention generally relates to methods for assessing the health of a tissue by characterizing circulating nucleic acids in a biological sample. According to certain embodiments, methods for assessing the health of a tissue include the steps of detecting a sample level of RNA in a biological sample, comparing the sample level of RNA to a reference level of RNA specific to the tissue, determining whether a difference exists between the sample level and the reference level, and characterizing the tissue as abnormal if a difference is detected.
US10240198B2	Nucleic acid probe and method of detecting genomic fragments Provided herein, among other things, is a method of processing a nucleic acid sample. In some embodiments, the method comprises a) hybridizing a sample comprising a target fragment to a nucleic acid probe comprising: i. a head sequence and a tail sequence, wherein the head and tail sequences are at the ends of a first oligonucleotide molecule; and ii. a splint sequence comprising, in order: an upstream flanking sequence that is complementary to the head sequence; a target complementary sequence that is complementary to the target fragment; and a downstream flanking sequence that is complementary to the tail sequence; thereby producing a hybridization product in which the ends of the target fragment are ligatably adjacent to the ends of the head and tail sequences in the first oligonucleotide molecule; and b) ligating the ends of the target fragment to the ends of the head and tail sequences of the first oligonucleotide molecule, thereby producing a cyclic product that comprises the target fragment and the head and tail sequences. Probes and kits for performing the method are also provided.
US10240197B1	Methods for analyzing nucleic acids from single cells Aspects of the present invention include analyzing nucleic acids from single cells using methods that include using tagged polynucleotides containing multiplex identifier sequences.
US10240194B2	Methods for nucleotide sequencing and high fidelity polynucleotide synthesis Methods of obtaining sequence information about target polynucleotide having a predefined sequence are disclosed. The methods include sequencing by ligation and sequencing by polymerase.
US10240193B2	Sequencing device A method of preparing reagents includes inserting a cartridge into an instrument. The cartridge includes a plurality of reagent enclosures disposed in a cavity of the cartridge and exposing a port to an exterior of the cartridge. Each reagent enclosure includes a reagent container including a reagent and an internal cavity defining a compressible volume, an opening defined through the reagent container to the internal cavity. The method further includes connecting a plurality of fluid ports to the openings of the plurality of reagent enclosures; applying a solution through the fluid ports to at least partially fill the plurality of reagent enclosures; and cycling a pressure of the cavity, whereby for each of the reagent enclosures, during increasing pressure, the solution enters the internal cavity of the reagent container, combines with the reagent, and compresses the compressible volume, and during decreasing pressure, the compressible volume decreases and the reagent is ejected through the opening.
US10240192B2	Bead emulsion nucleic acid amplification Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
US10240190B2	Nano-constructs for polynucleotide delivery The present invention provides novel nano-constructs useful for delivering polynucleotides into cells, methods of using the nano-constructs, and methods of making the nano-constructs.
US10240186B2	Devices, systems, and methods for magnetic separation Methods, microfluidic devices, and instruments for magnetic separation of particles from a fluid are described. Examples include microfluidic devices having a removable portion. Examples include microfluidic devices having one or more regions of reduced fluid velocity. Examples further including instruments having pneumatic interfaces. Examples further includes instruments having controllable magnets, imaging components, or combinations thereof.
US10240184B2	Covalent tethering of functional groups to proteins A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein.
US10240180B2	Multiplexed screening of enzyme activities using nanostructure-initiator mass spectrometry Disclosed herein are methods, compositions and systems for analyzing and detecting enzyme activity. For examples, methods, compositions and systems for parallel detection and analysis of enzymatic activities of enzymes in complex biological mixtures are provided.
US10240179B2	Method for the production of protein complexes and vaccine compositions comprising the same The present invention relates to methods for the production of heat shock protein complexes for use in vaccine compositions. In particular, there is provided a method for increasing the level and immunogenicity of heat shock protein complexes produced in cells by subjecting the cells to specific stress inducing stimuli. The invention further extends to the use of heat shock protein complexes produced according to the methods of the invention in the preparation of vaccine compositions for the prevention and treatment of infectious diseases and cancerous conditions.
US10240178B2	Mispriming prevention reagents Provided herein are mispriming prevention reagents, compositions and kits comprising such reagents and methods of use thereof.
US10240177B2	Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of at least partially degrading, cleaving, or removing polysaccharides, lignocellulose, cellulose, hemicellulose, lignin, starch, chitin, polyhydroxybutyrate, heteroxylans, glycosides, xylan-, glucan-, galactan-, or mannan-decorating groups using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius.
US10240176B2	Compositions and methods for producing benzylisoquinoline alkaloids The present invention relates to host cells that produce compounds that are characterized as benzylisoquinolines, as well as select precursors and intermediates thereof. The host cells comprise one, two or more heterologous coding sequences wherein each of the heterologous coding sequences encodes an enzyme involved in the metabolic pathway of a benzylisoquinoline, or its precursors or intermediates from a starting compound. The invention also relates to methods of producing the benzylisoquinoline, as well as select precursors and intermediates thereof by culturing the host cells under culture conditions that promote expression of the enzymes that produce the benzylisoquinoline or precursors or intermediates thereof.
US10240171B2	Preparation of lactic acid and/or a lactate salt from lignocellulosic material by separate saccharification and fermentation steps A process for preparing lactic acid and/or a lactate salt via the fermentation of carbohydrates obtained from lignocellulosic material. In particular the process includes: a) treating a lignocellulosic material with an alkaline agent including a caustic magnesium salt in the presence of water to provide a treated aqueous lignocellulosic material; b) saccharifying the treated aqueous lignocellulosic material in the presence of a hydrolytic enzyme to provide a saccharified aqueous lignocellulosic material including fermentable carbohydrates and a solid lignocellulosic fraction; c) fermenting the fermentable carbohydrates in the saccharified aqueous lignocellulosic material by way of lactic acid producing microorganism in the presence of an alkaline agent including a caustic magnesium salt to provide an aqueous fermentation broth including a magnesium lactate; and d) isolating lactic acid and/or lactate salt from the fermentation broth; wherein the saccharification step b) and the fermentation step c) are performed as two separate steps.
US10240170B2	CO hydratase and method for producing formate using the same Provided are CO hydratase and a method for producing formate using the same, and more specifically, to CO hydratase which is a novel enzyme which is produced by linking CO dehydrogenase (CODH) and CO2 reductase and can directly convert CO into formate, and use thereof.
US10240169B2	Recombinant microorganism for the production of useful metabolites Described are recombinant microorganisms characterized by having phosphoketolase activity, having a diminished or inactivated Embden-Meyerhof-Parnas pathway (EMPP) by inactivation of the gene(s) encoding phosphofructokinase or by reducing phosphofructokinase activity as compared to a non-modified microorganism and having a diminished or inactivated oxidative branch of the pentose phosphate pathway (PPP) by inactivation of the gene(s) encoding glucose-6-phosphate dehydrogenase or by reducing glucose-6-phosphate dehydrogenase activity as compared to a non-modified microorganism. These microorganisms can be used for the production of useful metabolites such as acetone, isobutene or propene.
US10240168B2	Altered host cell pathway for improved ethanol production A recombinant yeast cell, fermentation compositions, and methods of use thereof are provided. The recombinant yeast cell includes at least one heterologous nucleic acid encoding one or more polypeptide having phosphoketolase activity; phosphotransacetylase activity; and/or acetylating acetaldehyde dehydrogenase activity, wherein the cell does not include a heterologous modified xylose reductase gene, and wherein the cell is capable of increased biochemical end product production in a fermentation process when compared to a parent yeast cell.
US10240161B2	Compositions and methods for silencing gene expression A method of introducing naked dsRNA into a seed is provided. The method comprising contacting the seed with the naked dsRNA under conditions which allow penetration of the dsRNA into the seed, thereby introducing the dsRNA into the seed.
US10240160B2	Yeast cells expressing amyloid beta and uses therefor Disclosed are yeast cells expressing a polypeptide comprising a signal sequence and a human amyloid beta protein. Also disclosed are methods of screening yeast cells to identify compounds that prevent or suppress amyloid beta-induced toxicity and genetic suppressors or enhancers of amyloid beta-induced toxicity. Compounds identified by such screens can be used to treat or prevent neurodegenerative disorders such as Alzheimer's disease.
US10240152B2	Compositions and methods for inhibiting expression of transthyretin The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a transthyretin (TTR) gene, and methods of using the dsRNA to inhibit expression of TTR.
US10240149B2	Reduced size self-delivering RNAi compounds The present invention relates to methods for in vivo administration of sd-rxRNA molecules.
US10240147B2	Production of encoded chemical libraries This invention relates to the synthesis of nucleic acid-encoded chemical libraries using common adaptor sequences. Nucleic acid strands coupled to chemical moieties may be contacted with identifier oligonucleotides comprising coding sequences encoding the chemical moieties and an adaptor oligonucleotides, such that the adaptor oligonucleotide hybridizes to both the nucleic acid strands and the identifier oligonucleotides to allow ligation of the identifier oligonucleotides to the nucleic acid strands. The adaptor oligonucleotide is then removed. Nucleic acid-encoded chemical libraries, and methods of producing or screening such libraries are provided.
US10240146B2	Probe library construction The present invention generally relates to systems and methods for producing nucleic acids. In some aspects, relatively large quantities of oligonucleotides can be produced, and in some cases, the oligonucleotides may have a variety of different sequences and/or lengths. For instance, a relatively small quantity of oligonucleotides may be amplified to produce a large amount of nucleotides. In one set of embodiments, oligonucleotides may be amplified using PCR, then transcribed to produce RNA. The RNA may then be reverse transcribed to produce DNA, and optionally, the RNA may be selectively degraded or removed, relative to the DNA. In one set of embodiments, the oligonucleotides may be chemically modified. These modifications may include, but are not limited, to the adding of fluorescent dyes or other signaling entities.
US10240144B2	Sequential delivery device and method A reagent delivery method includes placing a reagent delivery column including a plurality of reagent storage elements therein in a centrifugal device, coupling a breaching element to the housing, and rotating the centrifugal device to force the reagent storage elements toward the breaching element, breaching of the reagent storage elements releasing reagent therein and communicating the same to an external environment. A reagent delivery system includes a column having a housing, a plurality of reagent storage element sheets positioned in the housing or forming a stack, a plurality of breaching elements, and a microplate having a plurality of wells, the microplate coupled to the housing where each well corresponds or aligns with a breaching element and a reagent storage element. The system can be rotated in a centrifugal device to force the reagent storage element stacks toward the breaching elements.
US10240142B2	Method of producing nanobiocatalysts A method of producing nanobiocatalysts includes: suspending a support material in a liquid medium; functionalizing a surface of the support material by mixing the suspended support material with a functionalizer for a first predefined time at a first predefined temperature, wherein a first broth results; applying a protein directly in the first broth after the first predefined time; mixing the protein with the first broth and incubating the protein for a second predefined time at a second predefined temperature, wherein a second broth results; immobilizing the incubated protein onto the functionalized surface of the support material, wherein a third broth results; filtering the third broth; and gathering a retentate of the filtering. By directly processing the first and second broths allows for providing a continuous process and production of the nanobiocatalysts, which can be optimized regarding time, water, chemical and energy consumption. Also, problems related to thixotrophy can be minimized.
US10240136B2	β-fructofuranosidase To provide an improved β-fructofuranosidase which is capable of efficiently producing kestose while inhibiting the production of nystose. This improved β-fructofuranosidase comprises either: an amino acid sequence (a) obtained by introducing, into the amino acid sequence represented by SEQ ID NO: 2, an amino acid mutation i) in which the 85th glycine (G) from the N-terminal is substituted for a protein-constituting amino acid other than glycine (G), and/or an amino acid mutation ii) in which the 310th histidine (H) from the N-terminal is substituted for lysine (K), arginine (R), or tyrosine (Y); or an amino acid sequence (b) which exhibits β-fructofuranosidase activity, and which comprises an amino acid sequence obtained by deleting, substituting, inserting, or adding one or more amino acids in (a) other than the amino acid into which the amino acid mutation has been introduced.
US10240131B2	Type II pseudorabies virus attenuated strain, its preparation method and application The present invention discloses a type II Pseudorabies virus attenuated strain and its preparation method and application. The attenuated strain of pseudorabies virus is gE/TK-double-deficient strain, which is named as PRV-HD/c strain of PRV dual-deletion strain, and the accession number is CGMCC No. 14325. The attenuated strain of the pseudorabies virus of the present invention is obtained from the newly isolated strain of pseudorabies virus type II after deletion of the gE and TK double genes and has reduced pathogenicity and strong immunogenicity and is inactivated by the attenuated strain of pseudorabies virus vaccines or live attenuated vaccines, which can provide effective immunity to PRV susceptible animals such as pigs and mice.
US10240129B2	Bacteriophage and composition comprising same The present invention relates to a novel bacteriophage ΦCJ25 (KCCM11463P) and a composition comprising the same as an active ingredient. In addition, the present invention relates to a method for preventing and/or treating infectious diseases caused by avian pathogenic Escherichia coli (APEC) of birds by using the bacteriophage ΦCJ25 (KCCM11463P) or the composition.
US10240127B2	Exosomes from clonal progenitor cells The invention provides methods, compositions, uses and kits relating to exosomes isolated from progenitor cells.
US10240123B2	Method for preparing induced paraxial mesoderm progenitor (IPAM) cells and their use The present invention relates to an ex vivo method for preparing induced paraxial mesoderm progenitor (iPAM) cells, said method comprising the step of culturing pluripotent cells in an appropriate culture medium comprising an effective amount of an activator of the Wnt signaling pathway and an effective amount of an inhibitor of the Bone Morphogenetic Protein (BMP) signaling pathway.
US10240122B2	Active-ester-group-containing composition for producing fibers, and cell culture scaffold material using fibers produced from active-ester-group-containing composition A composition for producing a fiber, containing (A) a polymer compound containing a unit structure represented by the formula (1) and a unit structure represented by the formula (2), (B) a crosslinking agent, (C) an acid compound, and (D) a solvent wherein each symbol in the formulas (1) and (2) is as described in the DESCRIPTION.
US10240120B2	Balanced mixotrophy method Methods of culturing mixotrophic microorganisms in a state of balanced gas composition are disclosed. Parameters of a culture of mixotrophic microorganisms may be controlled to reduce the requirements of externally supplied gases and optimize the production and consumption of gases within the culture by the phototrophic and heterotrophic metabolisms of the mixotrophic microorganisms.
US10240118B2	System for monitoring growth media A system for monitoring growth media within a controlled environment is provided and includes a well plate having a plate top and a plate side and defines at least one well cavity. The plate top includes a top opening and the plate side includes a side opening and the side opening is communicated with one of the at least one well cavity. The system includes a sensor assembly unit that includes a unit structure defining a reference material chamber containing a reference material, a sensor chamber having a chamber opening, and a base chamber. Additionally, the system includes a reference electrode communicated with the reference material and the base chamber. A media sensor is provided and is communicated with the chamber opening and a media sensor electrode communicated with the media sensor. The reference electrode and media sensor electrode are communicated with a processing device.
US10240112B2	Microemulsions and their use in metal working fluids, wood stains, or wood sealers The present disclosure is directed to compositions including a microemulsion comprising a blend of lecithin, a co-surfactant, and a salt of an acidifier, an ester of an acidifier, or combinations thereof. Uses of the compositions are also disclosed.
US10240111B2	Laundry additive A laundry additive composition comprising a) at least one oxylated material chosen from polyoxyalkylene, a polyoxyalkylene fatty acid ester, and a polyoxyalkylene fatty alcohol ether; b) a polyol; c) a coloring agent; and d) at least one additive chosen from fragrance and a fabric treatment material. The composition can deliver the additive to clothing during washing or rinsing of the clothes, such as to impart a fragrance to clothing.
US10240102B2	Lubricant compositions containing hexene-based oligomers Disclosed herein are oligomerization processes using feedstocks containing 1-hexene to produce an oligomer product, and methods for recovering a heavy 1-hexene oligomer from the oligomer product and hydrogenating the heavy 1-hexene oligomer. The resultant hydrogenated heavy 1-hexene oligomer can be blended with other PAO's to form 100 cSt and 40 cSt lubricant compositions, which have viscosity index and pour point properties that are equivalent to or better than respective 100 cSt and 40 cSt 1-decene PAO's.
US10240099B2	Processes for producing a fuel from a renewable feedstock Processes for the production of transportation fuel from a renewable feedstock. A catalyst is used which is more selective to hydrodeoxygenate the fatty acid side chains compared to decarboxylation and decarbonylation reactions. A gaseous mixture of carbon monoxide and hydrogen can be supplied to the conversion zone. Water may also be introduced into the conversion zone to increase the amount of hydrogen.
US10240098B2	Modular processes for the production of tight gas and tight oil and for tight oil refining Modular, portable processes and apparatus for the production of tight gas (including shale gas) and tight oil (including shale oil) and for the conversion of tight oil into a plurality of marketable fuels are described which enable easy deployment and start-up and are specifically useful in remote areas. Furthermore, these modular processes and apparatus are configured to use co-produced tight gas as a source of processing energy. Another feature of the modular processes is to substantially reduce the use of fracking water and process water. In some embodiments modular processes include (A) Purified Salt Production; (B) Modular Hydrochloric Acid (HCl) Production; (C) Hydrogen Production by Autothermal Reformer; (D) Optimized Hydraulic Fracturing; (E) Desalting with Bi-Electric Configuration with an Interchanger; (F) Desalter Water Recovery and Recyclling; (G) Precut Column with a Gas-Fired Heater; (H) Crude Distillation with a Gas-Fired Heater; (I) Hydrodesulfurization using Reactive Distillation; and (J) Vacuum Distillation.
US10240094B2	Conversion of oxygenates to hydrocarbons with variable catalyst composition Systems and methods are provided for modifying the composition of the conversion catalyst in a reactor for oxygenate conversion during conversion of an oxygenate feed to allow for adjustment of the slate of conversion products. The modification of the conversion catalyst can be performed by introducing a substantial portion (relative to the amount of catalyst inventory in the reaction system) of make-up catalyst having a distinct composition relative to the conversion catalyst in the reaction system. Introducing the distinct composition of make-up catalyst can modify the composition of the conversion catalyst in the reactor to allow for changes in the resulting product slate. By introducing the distinct catalyst composition, the conversion catalyst in the reactor can correspond to a different composition of catalyst than the overall average catalyst composition within the catalyst inventory in the reaction system.
US10240093B2	Method and equipment for producing hydrocarbons by catalytic decomposition of plastic waste products in a single step A method having the following steps: subjecting plastic waste material to a thermal pre-treatment in order to produce a liquid plastic mass, wherein the thermal pre-treatment of the plastic material is carried out in an inert gas atmosphere at a temperature that varies between 110° C. and 310° C.; simultaneously feeding the liquid plastic mass to a reaction apparatus; bringing the plastic mass into contact with a bed of particles of inorganic porous material contained inside the reaction apparatus at a temperature of between 300° and 600° C.; inducing thermocatalytic decomposition reactions at a temperature of between 300 and 600° C. in order to generate a mixture of hydrocarbons in a vapor phase; and separating the hydrocarbons from the vapor phase current generated inside the reaction means in order to produce a liquid mixture of hydrocarbons.
US10240091B2	Process for devolatizing a feedstock Provided herein is a method for devolatizing a solid feedstock. The solid feedstock is treated to a produce a particle size laying between 1 cm3 and 100 cm3. The solid feedstock is passed into a device connected to an outlet of a compaction screw auger comprising an assembly including a solid feedstock injector, a retort, a side arm for injecting a heated gas comprising hydrogen, and a process auger. The solid feedstock is contacted with the heated gas at a temperature of 500° C. to 1000° C. for a time of 60 seconds to 120 seconds, whereby the solid feedstock is converted into a gas stream and a solid stream.
US10240089B2	Gypsum composites used in fire resistant building components A composite product includes gypsum in an amount of 60 to 90% by weight, fibers in an amount of 1.5 to 26% by weight substantially homogeneously distributed through the composite, and a rheology-modifying agent in an amount of 0.5 to 6% by weight. The composite is caused or allowed to cure to form a cured composite. The cured composite is a fire resistant component used in a fire-rated door core, a fire-rated door or a fire-rated building panel. The fire resistant component may include a building panel, a door panel, a door core, a door rail, a door stile, a door lock block, a door border, or a door insert.
US10240087B2	Enhanced color-preference LED light sources using lag, nitride, and PFS phosphors According to some embodiments, a composite light source includes at least one blue light source having a peak wavelength in the range of about 400 nanometer (nm) to about 460 nm; at least one LAG phosphor; at least one narrow red down-converter; and wherein the composite light source has a Lighting Preference Index (LPI) of at least 120. Numerous other aspects are provided.
US10240084B2	Non-crystallizable pi-conjugated molecular glass mixtures, charge transporting molecular glass mixtures, luminescent molecular glass mixtures, or combinations thereof for organic light emitting diodes and other organic electronics and photonics applications The present invention provides charge transporting molecular glass mixtures, luminescent molecular glass mixtures, or combinations thereof comprising at least two nonpolymeric compounds each independently corresponding to the structure (R1Y1)p[(Z1Y2)mR2Y3]nZ2Y4R3 wherein m is zero or one; n is zero up to an integer at which said compound starts to become a polymer; p is an integer of from one to eight; each R1 and R3 is independently a monovalent aliphatic or cycloaliphatic hydrocarbon group having 1 to 20 carbon atoms, an aromatic group or a multicyclic aromatic nucleus; R2, Z1, and Z2 each independently represent multivalent aliphatic or cycloaliphatic hydrocarbon groups having 1 to 20 carbon atoms or an aromatic group; and Y1, Y2, Y3 and Y4 each independently represent a triple bond, a double bond, or a single bond link.
US10240082B2	Method for design of production wells and injection wells The disclosure claimed herein relates to well systems for various fluids production, in particular, for production of fluids from hydrocarbon-containing formations using hydraulic fracturing process. According to the proposed method, injecting into well of fracturing fluid not containing proppant is performed to form a fracture in the formation, after which fracturing fluid is injected into the wellbore in pulse mode; the pulse mode provides at least one pulse of injecting fracturing fluid containing proppant, and at least one pulse of proppant-free fluid. Also, methods for fluid production and injection are proposed. Methods for fluids production, injection and recovery using hydraulic fracturing method are proposed. The proposed method increase the well lifetime due to reduced fluid flow impact on fracture walls and proppant clusters.
US10240078B2	Volatile surfactant treatment for use in subterranean formation operations Methods including providing a treatment fluid comprising: a gas; and a volatile surfactant dispersed in the gas, wherein the volatile surfactant has a normal boiling point of less than 260° C. without substantial thermal decomposition and a dynamic surface tension of less than about 40 dynes/cm for a 0.1% solution; and intermittently introducing the treatment fluid and an aqueous fluid into a treatment zone in a subterranean formation.
US10240077B2	Low density oil external emulsion with gelled internal phase as a gravel packing carrier fluid A subterranean treatment fluid may include an invert emulsion including a clarified diutan-based gelled aqueous internal phase and a mineral oil-based external phase, and an acid composition. The acid composition may include at least one acid selected: formic acid, acetic acid, propionic acid, lactic acid, glycolic acid, and combinations thereof, at least one acid-generating compound selected from: an ester; an aliphatic polyester; an ortho ester; a poly(ortho ester); an ortho ether; a poly(ortho ether); a lactide; a poly(lactide); a glycolide; a poly(glycolide); an ε-caprolactone; a poly(ε-caprolactone); a hydroxybutyrate; a poly(hydroxybutyrate); an anhydride; a poly(anhydride); an aliphatic carbonate; an aliphatic polycarbonate; an amino acid; a poly(amino acid), and combinations thereof, or a combination of the at least one acid and the at least one acid-generating compound. The subterranean treatment fluid may have a density less than water.
US10240076B2	Self-adhesive bituminous sheath for building and bitumen modifier for self-adhesive bituminous sheath An adhesive bituminous sheath for building includes bitumen and an adhesivizing additive mixed with the bitumen, wherein the adhesivizing additive is an aliphatic and cycloaliphatic resin.
US10240075B2	Bonding dissimilar materials with adhesive paste A rivetable adhesive for use in a joint between dissimilar materials, comprising a liquid epoxy resin, an expoxidized polysulfide, a flexibilizer, a solid epoxy CTBN adduct based upon bisphenol A, a phenoxy resin, an impact modifier including methacrylate-butadiene-styrene, a curing agent; and a blowing agent. The adhesive finds particular suitability for use in riveting aluminum panels to steel structures, such as for forming automotive vehicle roof structures.
US10240072B2	Compositions with a grafted polyolefin copolymer having constituents of an unsaturated monomer, an olefin elastomer, and a long-chain branched polyolefin The present disclosure provides a polyolefin-based composition, suitable for use as a tie-layer adhesive composition, and a process for making the polyolefin-based composition. The polyolefin-based composition is made from and/or contains a grafted polyolefin copolymer composition, a base resin composition, and optionally, an additives composition. The grafted polyolefin copolymer composition is made from and/or contains a grafted polyolefin composition, an olefin elastomer composition, and a long-chain branched polyolefin composition. The grafted polyolefin is coupled to the olefin elastomer and the long-chain branched polyolefin.
US10240071B2	Aqueous adhesive dispersion containing polyurethanes and ethoxylated fatty alcohols Described are aqueous adhesive dispersions comprising dispersed polyurethanes and also ethoxylated fatty alcohols as emulsifiers. The polyurethanes are constructed from certain organic diisocyanates, dihydroxy compounds selected from certain polyester diols and polyether diols, and compounds having groups reactive toward isocyanate groups and having at least one ionic group. The adhesive dispersions can be used as laminating adhesives, for example for composite film lamination or for the lamination of rigid moldings with flexible decorative foils.
US10240070B1	Electronically reversible adhesive systems An adhesive system for attachment to a contact surface of an object comprises a backing, carbon nanotubes, charged nanoparticles, and an electrical source. The carbon nanotubes each have a first end region and a second end region, opposite the first end region. Each of the charged nanoparticles is coupled to the second end region of at least one of the carbon nanotubes. The electrical source is configured to selectively electrically charge the backing to cause an electrical repulsion force between the backing and the charged nanoparticles. The first end region of each of the carbon nanotubes is coupled to the backing. The second end region of each of a number of the carbon nanotubes is coupled to none of the charged nanoparticles.
US10240066B2	Methods of producing polyurea three-dimensional objects from materials having multiple mechanisms of hardening A method of forming a three-dimensional object of polyurethane, polyurea, or copolymer thereof is carried out by: (a) providing a carrier and an optically transparent member having a build surface, the carrier and the build surface defining a build region therebetween; (b) filling the build region with a polymerizable liquid, the polymerizable liquid including at least one of: (i) a blocked or reactive blocked prepolymer, (ii) a blocked or reactive blocked diisocyante, or (iii) a blocked or reactive blocked diisocyanate chain extender; (c) irradiating the build region with light through the optically transparent member to form a solid blocked polymer scaffold and advancing the carrier away from the build surface to form a three-dimensional intermediate having the same shape as, or a shape to be imparted to, the three-dimensional object, with the intermediate containing the chain extender; and then (d) heating or microwave irradiating the three-dimensional intermediate sufficiently to form from the three-dimensional intermediate the three-dimensional object of polyurethane, polyurea, or copolymer thereof.
US10240065B2	Reversible, chemically or environmentally responsive polymers, and coatings containing such polymers We have demonstrated reversibly reducing metal-ion crosslinkages in polymer systems, by harnessing light, creating a dynamic and reversible bond. The reduction induces chemical and physical changes in the polymer materials. Some variations provide a polymer composition comprising: a polymer matrix containing one or more ionic species; one or more photosensitizers; and one or more metal ions capable of reversibly changing from a first oxidation state to a second oxidation state when in the presence of the photosensitizers and light. Some embodiments employ urethane-based ionomers capable of changing their crosslinked state under the influence of a change in counterion valance, using light or chemical reducing agents. This invention provides films, coatings, or objects that are reversible, re-mendable, self-healing, mechanically adjustable, and/or thermoplastic/thermoset-switchable.
US10240059B2	Cationic latex fixative for ink applications A cationic latex fixative for ink applications is provided. The cationic latex fixative derived from a combination of a cationic monomer, a nonionic monomer that provides softness to the latex, and a nonionic monomer that provide stiffness to the latex. A method of manufacturing the fixative and a method of printing the fixative are also provided.
US10240056B2	Aqueous resin based inkjet inks An inkjet ink includes a) an aqueous medium; and b) capsules composed of a polymeric shell surrounding a core; wherein the capsules are dispersed in the aqueous medium using a dispersing group covalently bonded to the polymeric shell; wherein the core contains a photoinitiator and one or more chemical reactants capable of forming a reaction product upon application of UV light; wherein the capsules have an average particle size of no more than 4 μm as determined by dynamic laser diffraction; and wherein the photoinitiator is a diffusion hindered photoinitiator selected from the group consisting of multifunctional photoinitiators, oligomeric photoinitiators, polymeric photoinitiators and polymerizable photoinitiators.
US10240055B2	Ink jet ink composition and production method thereof An ink jet ink composition includes a disperse dye, and a sodium naphthalene sulfonate formalin condensate, in which a ratio of a concentration of sodium ions with respect to a content of the sodium naphthalene sulfonate formalin condensate (Na(ppm)/NSF (% by mass)) is 75 to 550.
US10240054B2	Method for manufacturing aqueous pigment dispersion and aqueous ink for inkjet recording Provided is a method for producing an aqueous pigment dispersion including a step of dispersing a mixture containing a pigment, an anionic group-containing organic polymer compound, a basic compound, and from 1% to 500% by mass of alkylene oxide adduct having a polyamine structure with respect to the pigment into water. The step of dispersing includes Step 1 of kneading a mixture which contains a pigment, an anionic group-containing organic polymer compound, a basic compound, and from 1% to 500% by mass of alkylene oxide adduct having a polyamine structure with respect to the pigment, and which contains no water or water equal to or less than 30% by mass with respect to a solid content thereof, and Step 2 of dispersing a kneaded material obtained in Step 1 into water.
US10240053B2	Aqueous ink, ink cartridge, and ink jet recording method An aqueous ink for ink jet having a high color developing property, capable of recording an image having an excellent hue, and having excellent storage stability, containing a coloring material and a water-soluble organic solvent is provided. The coloring material is a compound represented by the following General Formula (1). The water-soluble organic solvent contains a first water-soluble organic solvent having two or more hydroxy groups and having a Log P value of −1.88 or more to −1.09 or less. The content (mass %) of the first water-soluble organic solvent is 5.0 times or more to 30.0 times or less by a mass ratio with respect the content (mass %) of the coloring material.
US10240049B2	Superhydrophobic and oleophobic coatings with low VOC binder systems Coating compositions for the preparation of superhydrophobic (SH) and/or oleophobic (OP) surfaces that employ low amounts of volatile organic compounds are described. Also described are the resulting coatings/coated surfaces and methods of their preparation. Such coatings/surfaces have a variety of uses, including their ability to prevent or resist water, dirt and/or ice from attaching to a surface.
US10240046B2	Method for fabrication of a hybrid dual phase filler for elastomers The method for fabricating a hybrid dual phase filler for elastomers includes: impregnation of carbon black with ethanol suspension of magnetite in a ball mill; drying of the dual phase mixture till constant weight; grinding of the dried product in a ball mill; thermal activation under vacuum in a specifically designed reactor followed by a grinding of the final product in a ball mill. The hybrid dual phase filler includes carbon black impregnated with ethanol suspension of magnetite, contains 5 to 50 mass % of magnetite and 95 to 50 mass % of carbon black. Magnetite is a powder and includes up to 5% of SiO2, particle size up to 50μ and density of 4.8-5.2 g/cm3 with a specific surface area (BET/) 400-900 m2/g; iodine number—370-750 mg/g; oil number 200-450 ml/100 g; total volume pore 0.5-1.5 cm3(STP)/g; micropore surface area 50-90 m2/g; external specific surface area 400-900 m2/g.
US10240041B2	Fire suppression fluid dispensing device Disclosed is an assembly for discharging hydrated super absorbent polymer into a confined space for protection of a lineman or firefighter from a flash fire and fire suppression. A pressurized tank is filled with hydrated super absorbent polymer and connected to a conduit that is constructed and arranged to interchange various nozzles for personnel protection and fire suppression. The hydrated super absorbent polymer is discharged through a solenoid valve which can be operated by the individual operating within the space with a switch, an individual operating the control panel mounted in a utility truck or activated by a heat sensor in the confined space.
US10240033B2	Optical film and method for manufacturing same, polarization plate, and liquid crystal display apparatus The optical film of the present invention is an optical film including a thermoplastic resin, in which the optical film has a moisture permeability of 70 g/m2/day or less (in terms of a film thickness of 40 μm), and contains a moisture permeability-reducing compound having a molecular weight of 200 or more and satisfying Formula (1) described below. Formula (1) A/B≤0.9 (A represents a moisture permeability of an optical film in a case in which 10 mass % of the moisture permeability-reducing compound is added to the mass of the thermoplastic resin, and B represents a moisture permeability of an optical film in a case in which the thermoplastic resin is included and the moisture permeability-reducing compound is not added.)
US10240032B2	Binder for powder metallurgy, mixed powder for powder metallurgy, and sintered body The present invention provides a binder which has excellent effect on suppression of segregation or dust emission, while exhibiting excellent fluidity both at ordinary temperatures and at high temperatures. The present invention is a binder which is blended for use in a mixed powder for powder metallurgy, said mixed powder containing an iron-based powder and an auxiliary starting material powder. This binder is characterized by being composed of one or more polymers that are selected from among butene polymers having a melting point of from 50° C. to 85° C. (inclusive) and a heated melt fluidity at 190° C. of from 2.0 g/10 minutes to 3.6 g/10 minutes (inclusive) and methacrylic acid polymers having a weight average molecular weight of 1,000,000 or less.
US10240030B2	Article comprising a high flow polyetherimide composition Molded articles having a maximum thickness of 3 centimeters and including a polyetherimide composition are described. The polyetherimide compositions include 60 to 99.9 weight percent of a polyetherimide having a weight average molecular weight of 5,000 to 80,000 Daltons, and 0.1 to 40 weight percent of an aryl phosphate having a molecular weight from 500 to 1,200 Daltons, wherein weight percent is based on the total weight of the composition. The compositions have a melt flow at least 10% greater than the melt flow of the same polyetherimide composition without the aryl phosphate, measured according to ASTM D1238 at 337° C. under a 6.7 kilogram load.
US10240029B2	Plastic modifiers Hydrocarbyl terminated polyester compounds comprising sulfur-containing repeat units that are useful as plastic modifiers, polymer blend compositions comprising the hydrocarbyl terminated polyester compounds, methods for modifying the performance properties of polymers, and methods for preparing the hydrocarbyl terminated polyester compounds.
US10240027B2	Indoline-nitroxide radical as stabilizer and inhibitor for reactive resins, reactive resins containing same and use of same Use of a stable indole-nitroxide radical as a stabilizer and/or inhibitor for resin mixtures and reactive resin mortars is described on the basis of radically curable compounds. Resin mixtures and reactive resin mortars may be made stable in storage very effectively using the indole nitroxide radical and the pot life of mortar compositions can be adjusted in a targeted manner.
US10240025B2	Compositions comprising estolide compounds and methods of making and using the same Provided herein are compositions comprising at least one estolide compound of formula: in which n is an integer equal to or greater than 0; m is an integer equal to or greater than 1; R1, independently for each occurrence, is selected from optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched; R2 is selected from hydrogen and optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched; and R3 and R4, independently for each occurrence, are selected from optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched. Also provided are uses of the compositions described herein.
US10240024B2	Nucleating composition and thermoplastic polymer composition comprising such nucleating composition The invention relates to a nucleating composition comprising: (a) a first nucleating agent, which comprises a cyclic dicarboxylate salt compound; and (b) a second nucleating agent, which comprises talc, wherein the cyclic dicarboxylate salt compound has the formula (I):
US10240023B2	Polymer-ceramic composites Polymer-ceramic composites, in particular for the field of electronics, include grains of titanium suboxides of general formulation TiOx in which x is between 1.00 and 1.99, limits included, and/or of barium and/or strontium titanate suboxides of general formulation Ba(1-m)SrmTiOy in which y is between 1.50 and 2.99, limits included, and m is between 0 and 1, limits included.
US10240019B2	Injection-foamable styrenic monomer-diolefin copolymer, a method for the preparation thereof and use thereof A styrenic monomer-diolefin copolymer comprises polystyrenic monomer micro-blocks and polydiolefin micro-blocks, in which the content of styrenic monomer units is 10-80 wt %, the ratio of diolefin units of 1,2-structure is less than 30% in the total diolefin units, and the number-average molecular weight (Mn) of the copolymer is 25,000-500,000. The preparation methods and uses in foam products thereof are also disclosed.
US10240014B2	High clarity and strength polyethylene films A film having an A/B/A structure comprising an layer A and a layer B. The layer A is present in an amount ranging from 25 to 65 wt. %, based upon the total weight of the A/B/A structure, and the layer A comprises a first A layer and a second A layer each independently comprise linear low density polyethylene. The layer B is present in an amount ranging from 35 to 75 wt. %, based upon the total weight of the A/B/A structure, and the layer B, which comprises high density polyethylene, is positioned between the first A layer and the second A layer.
US10240013B2	Microporous material from ethylene-chlorotrifluoroethylene copolymer and method for making same Microporous material having a spherulitic matrix made from ethylene chlorotrifluoroethylene copolymer has a plurality of pores having an average pore size greater than about 0.01 micrometer. The material is made by thermally induced phase separation (TIPS) process that includes melt mixing ethylene chlorotrifluoroethylene copolymer, diluent and nucleating agent to provide a melt mixed composition; shaping the melt mixed composition; cooling the shaped melt mixed composition to induce phase separation of the ethylene chlorotrifluoroethylene copolymer to provide a phase separated material; and stretching the phase separated material to provide the microporous material. The microporous material may be incorporated into articles and the articles may include one, two or more layers of microporous material.
US10240011B2	Multifunctional curing agents and their use in improving strength of composites containing carbon fibers embedded in polymeric matrix A functionalized carbon fiber having covalently bound on its surface a sizing agent containing epoxy groups, at least some of which are engaged in covalent bonds with crosslinking molecules, wherein each of said crosslinking molecules possesses at least two epoxy-reactive groups and at least one free functional group reactive with functional groups of a polymer matrix in which the carbon fiber is to be incorporated, wherein at least a portion of said cros slinking molecules are engaged, via at least two of their epoxy-reactive groups, in crosslinking bonds between at least two epoxy groups of the sizing agent. Composites comprised of these functionalized carbon fibers embedded in a polymeric matrix are also described. Methods for producing the functionalized carbon fibers and composites thereof are also described.
US10240006B2	Upgrading lignin from lignin-containing residues through reactive extraction Disclosed are methods of functionalizing lignin using reactive extraction. The invention also generally relates to functionalized lignin. An exemplary method for producing functionalized lignin is disclosed, which comprises: providing a residue comprising lignin and cellulose; subjecting the residue to a liquid comprising an organic compound, thereby forming a first mixture; wherein the subjecting is performed at a first temperature of about 100° C. or less; and wherein the first mixture comprises: a first liquid fraction comprising solubilized functionalized lignin, wherein the solubilized functionalized lignin is functionalized with the organic compound; and a first solid fraction comprising cellulose.
US10240004B2	Polymeric BODIPY dyes and methods for using the same Polymeric BODIPY dyes including light harvesting BODIPY unit-comprising multichromophores are provided. In some embodiments, the dyes are polymeric tandem dyes that include a light harvesting BODIPY unit-comprising multichromophore and an acceptor chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. The polymeric tandem dyes may be covalently linked to a specific binding member. Also provided are methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule using compositions including the polymeric tandem dyes. Kits and systems for practicing the subject methods are also provided.
US10240000B2	Aromatic polyimides suitable for 3D printing processes Novel aromatic polyimides are disclosed with sufficient physical properties to be useful in 3D printing.
US10239999B2	Curable resin, spacer composition, filter, methods of preparing the same, and display device Disclosed are a curable resin, a spacer composition, a filter, methods of preparing the same, a filter and a method of preparing the same, and a display device. The curable resin includes 1 part by weight of dianhydride, 0.6 to 2 parts by weight of diamine, and 0.8 to 3 parts by weight of vinyl monomer.
US10239997B2	Surface treatment agent for substrate, comprising perfluoropolyether group-containing phosphate compound To provide a surface treatment agent capable of imparting excellent water/oil repellency, fingerprint stain removability, abrasion resistance and lubricity to the surface of a substrate.A surface treatment agent for a substrate, comprising a perfluoropolyether group-containing phosphate compound, a coating agent comprising the surface treatment agent and a liquid medium, and a substrate having a surface layer formed from the surface treatment agent or the coating agent.
US10239996B2	Process for preparing polymers A process for preparing non-naturally-occurring defined monomer sequence polymers is provided, and in which a high degree of synthetic control is obtained by the use of solvent resistant diafiltration membranes. Also provided is a process for separating non-naturally-occurring defined monomer sequence polymers from synthetic by-products or excess reagents using solvent resistant diafiltration membranes, and a use of a solvent resistant diafiltration membrane in processes for preparing and separating non-naturally-occurring defined monomer sequence polymers.
US10239994B2	Composition comprising titanium or zirconium alkoxide or aryloxide and use thereof The invention relates to a composition comprising a titanium or zirconium alkoxide or aryloxide, wherein the alkoxy group in the titanium or zirconium alkoxide is a group of formula R—O− wherein R is an alkyl group having 1 to 4 carbon atoms and the aryloxy group in the titanium or zirconium aryloxide is a group of formula Ar—O− wherein Ar is an aryl group having 6 to 12 carbon atoms, and wherein the composition additionally comprises 0.1 to 50 wt. % of an organic carbonate, based on the total weight of the composition.
US10239992B2	Carbon black modified polyesters Embodiments of the disclosure generally provide compositions and methods involving the production of polyester composite materials that contain covalently bonded carbon black particles. The carbon black particles have surface functional groups that enable the grafting of a polyester, and/or initiate the ring opening of a monomer to create a polyester grown from the surface of the particle.
US10239987B2	Aqueous polyurethane—vinyl polymer hybrid dispersions The invention relates to aqueous polyurethane-vinyl polymer hybrid dispersions comprising, as building blocks, hydrophobically modified hydroxy-functional polyesters A, acids B that have further groups which react with isocyanates under formation of urethanes, ureas, or thiourethanes, compounds G having only one hydroxyl group, and one or more tertiary amino groups, olefinically unsaturated monomers H2 having a polymerisable ethylenic unsaturation and a further functional group which reacts with an isocyanate group under bond formation, olefinically unsaturated monomers H1 having at least one polymerisable ethylenic unsaturation and no further functional group which reacts with an isocyanate group, and multifunctional isocyanates I having at least two isocyanate groups per molecule, to a process of their preparation, and to a method of use thereof.
US10239985B2	Polymer polyols comprising a natural oil base polyol, polyurethane foams comprising these polymer polyols and processes for their preparation This invention relates to polymer polyols comprising the free-radical polymerization product of a base polyol, at least one ethylenically unsaturated monomer, and, optionally, a preformed stabilizer, in the presence of at least one free-radical polymerization initiator and at least one chain transfer agent, in which the base polyol is a natural oil. A process for preparing these polymer polyols is also described. The present invention also relates to a polyurethane foam prepared from these polymer polyols and to a process for the preparation of these polyurethane foams.
US10239984B2	Process for the production of di- and polyamines of the diphenylmethane series The invention relates to a production process for polyamines through condensation of aromatic amines with formaldehyde employing at least one solid zeolite catalyst partially or fully ion-exchanged to the protonic form which has been A) alkaline-treated, wherein the alkaline treatment is in case of BEA zeolites carried out in the presence of a pore-directing agent and in case of zeolites other than BEA zeolites in the presence or absence of a pore-directing agent, or B) acid-treated without any alkaline treatment preceding or following said acid treatment, wherein the acid treatment is effected with an organic acid with chelating function.
US10239980B2	Block copolymer The present application provides the block copolymers and their application. The block copolymer has an excellent self assembling property and phase separation and various required functions can be freely applied thereto as necessary.
US10239979B2	Highly saturated nitrile rubber composition and cross-linked rubber A highly saturated nitrile rubber composition obtained by mixing 7 to 40 wt % of a carboxyl group-containing highly saturated nitrile rubber (A1) containing 15 to 60 wt % of α,β-ethylenically unsaturated nitrile monomer units and 1 to 60 wt % of α,β-ethylenically unsaturated dicarboxylic acid monoester monomer units and having an iodine value of 120 or less, 10 to 78 wt % of a highly saturated nitrile rubber (A2) containing α,β-ethylenically unsaturated nitrile monomer units in 15 to 60 wt %, having a content of α,β-ethylenically unsaturated dicarboxylic acid monoester monomer units of 0.9 wt % or less, and having an iodine value of 120 or less, and 15 to 50 wt % of a polyester resin (B) at a temperature of a melting point of the polyester resin (B) or more is provided.
US10239977B2	Producing polyolefin products Catalyst systems and methods for making and using the same are described. A method includes selecting a catalyst blend using a blend polydispersity index (bPDI) map. The polydispersity map is generated by generating a number of polymers for at least two catalysts. Each polymer is generated at a different hydrogen to ethylene ratio. At least one catalyst generates a higher molecular weight polymer and another catalyst generates a lower molecular weight polymer. A molecular weight for each polymer is measured. The relationship between the molecular weight of the polymers generated by each of the catalysts and the ratio of hydrogen to ethylene is determined. A family of bPDI curves for polymers that would be made using a number of ratios of a blend of the at least two catalysts for each of a number of ratios of hydrogen to ethylene. A ratio for the catalyst blend of the catalysts that generates a polymer having a bPDI that matches a polymer fabrication process is selected, and the product specific polyolefin is made using the catalyst blend.
US10239972B2	Active-energy-ray-curable composition, cured material, composition stored container, two-dimensional or three-dimensional image forming apparatus, and two-dimensional or three-dimensional image forming method An active-energy-ray-curable composition including: polymerizable monomer (A1) containing one (meth)acryloyl group; acylphosphine oxide-based polymerization initiator (B1); and acridone-based polymerization initiator (B2), an amount of the polymerizable monomer (A1) containing one (meth)acryloyl group being from 50.0% by mass through 99.8% by mass.
US10239971B2	Heavy goods vehicle tire comprising a tread based on a modified polyisoprene, process for preparing same A heavy-duty vehicle tire comprising a tread consisting of a crosslinked rubber composition comprising a reinforcing filler of siliceous type and a synthetic polyisoprene modified by grafting with a compound comprising at least one group Q, and at least one group A, which are joined to one another by at least one and preferably one “spacer” group Sp, in which: Q comprises a dipole containing at least one and preferably one nitrogen atom, A comprises an associative group comprising at least one nitrogen atom, Sp is an atom or group of atoms forming a bond between Q and A. The heavy-duty vehicle tire according to the invention has a satisfactorily improved rolling resistance/wear resistance compromise.
US10239969B2	Spherical magnesium halide adduct, a catalyst component and a catalyst for olefin polymerization prepared therefrom A magnesium halide adduct represented by the formula (I): MgX2.mROH.nE.pH2O, in which X is chlorine, bromine, a C1-C12 alkoxy, a C3-C10 cycloalkoxy or a C6-C10 aryloxy, with the proviso that at least one X is chlorine or bromine; R is a C1-C12 alkyl, a C3-C10 cycloalkyl or a C6-C10 aryl; E is an o-alkoxybenzoate compound represented by the formula (II): in which R1 and R2 groups are independently a C1-C12 linear or branched alkyl, a C3-C10 cycloalkyl, a C6-C10 aryl, a C7-C10 alkaryl or an C7-C10 aralkyl, the R1 and R2 groups are identical to or different from the R group; m is in a range of from 1.0 to 5.0; n is in a range of from 0.001 to 0.5; and p is in a range of from 0 to 0.8, is disclosed. A catalyst component useful in olefin polymerization, which comprises a reaction product of (1) the magnesium halide adduct, (2) a titanium compound, and optionally (3) an electron donor compound, is also disclosed.
US10239967B2	Olefin polymerization catalyst system comprising mesoporous organosilica support A catalyst system comprising a combination of: 1) one or more catalyst compounds comprising at least one nitrogen linkage; 2) a support comprising an organosilica material, which is a mesoporous organosilica material; and 3) an optional activator. Useful catalysts include pyridyldiamido transition metal complexes, HN5 compounds, and bis(imino)pyridyl complexes. The organosilica material is a polymer of at least one monomer of Formula [Z1OZ2SiCH2]3(1), where Z1 represents a hydrogen atom, a C1-C4alkyl group, or a bond to a silicon atom of another monomer and Z2 represents a hydroxyl group, a C1-C4alkoxy group, a C1-C6 alkyl group, or an oxygen atom bonded to a silicon atom of another monomer. This invention further relates to processes to polymerize olefins comprising contacting one or more olefins with the above catalyst system.
US10239964B2	Method for manufacturing conjugated diene polymer, conjugated diene polymer, rubber composition, and tire A method for manufacturing a conjugated diene polymer that can increase the robustness of a polymerization reaction system is provided. Also, a conjugated diene polymer, with a high cis-1,4-bond content, that is manufactured by this method for manufacturing is provided. A method for manufacturing a conjugated diene polymer includes polymerizing a conjugated diene monomer using a polymerization catalyst composition including a rare earth element compound and a compound having a cyclopentadiene skeleton, and a conjugated diene polymer manufactured with this method for manufacturing has a cis-1,4-bond content of 95% or greater.
US10239961B2	Cyclodextrin The invention provides a method for preparing sulphoalkyl ether-β-cyclodextrin. The method comprises first contacting cyclodextrin with a base to form activated cyclodextrin. The method then comprises separately contacting the activated cyclodextrin with an alkyl sultone to form sulphoalkyl ether-β-cyclodextrin. The activation reaction is carried in batch and the sulphoalkylation reaction is carried out under continuous flow conditions.
US10239952B2	Anti-WT1/HLA bi-specific antibody Disclosed herein is a bi-specific form of a T cell receptor mimic (TCRm) mAb with reactivity to human immune effector cell antigen and a WT1 peptide/HLA-A epitope. This antibody selectively bound to leukemias and solid tumor cells expressing WT1 and HLA-A as well as activated resting human T cells to release interferon-(IFN-γ) and to kill the target cancer cells in vitro. Importantly, the antibody mediated autologous T cell proliferation and directed potent cytotoxicity against fresh ovarian cancer cells. Therapeutic activity in vivo of the antibody was demonstrated in NOD SCID SCID Yc*(NSG) mice with three different human cancers expressing WT1/HLA-A2 including disseminated Ph+ acute lymphocytic leukemia (ALL), disseminated acute myeloid leukemia, and peritoneal mesothelioma. In both of the leukemia xenograft models, mice that received the antibody and T cells also showed longer survival and delayed limb paralysis. Also provided are methods for stimulating a primary T cell response comprising stimulating cytotoxic T cells against a first tumor antigen and a secondary T cell response comprising stimulating effector T cells and/or memory T cells against a first tumor antigen and/or against a second tumor antigen using the bi-specific antibodies described herein.
US10239951B2	Bispecific HER2 and HER3 antigen binding constructs Described herein are isolated bi-specific antigen binding constructs, e.g., antibodies. The bi-specific antigen binding constructs include two antigen binding polypeptide constructs, e.g., a Fab and an scFv. The first antigen-binding polypeptide construct monovalently and specifically binds to extracellular domain 4 (ECD4) of HER2 (human epidermal growth factor receptor 2); the second antigen-binding polypeptide construct monovalently and specifically binds to an extracellular domain (ECD) of HER3 (human epidermal growth factor receptor 3). One antigen binding polypeptide construct is a Fab format and the other antigen binding polypeptide construct is an scFv format. The bi-specific antigen binding constructs includes an Fc having two Fc polypeptides each having a CH3 domain for dimerization. Each Fc polypeptide is linked to the C-terminus of one of the antigen binding polypeptide constructs with or without a linker.
US10239950B2	Anti-MUC1 antibody or antigen-binding fragment thereof and uses thereof The present invention provides: an antibody exhibiting specificity for MUC1, the antibody having a glycan structure expressed at high levels in cancer cells; a method for manufacturing this antibody; and a novel means and method for the diagnosis and prevention and/or treatment of cancer using this antibody. The present invention is a monoclonal antibody to human MUC1, wherein the antibody specifically recognizes a glycopeptide having a human MUC1 tandem unit and furthermore having an O-linked glycan core (0(Tn)) in any one of the threonine and serine in the amino acid sequence of this human MUC1 tandem unit. A method for detecting MUC1 in a human body-fluid sample. A kit including this monoclonal antibody. A pharmacological composition for the prevention and/or treatment of a malignant tumor, the pharmacological composition containing this monoclonal antibody as an active ingredient.
US10239949B2	Oncofetal antigen binding proteins and related compositions and methods The present disclosure relates to protein molecules that specifically bind to 5T4 and/or 4-1BB. The molecules may have at least one humanized 5T4-binding or 4-1BB-binding domain. Such molecules are useful for the treatment of cancer. The protein molecule binding to 5T4 or 4-1BB may have a second binding domain that binds to another target. The molecules may bind both 5T4-expressing cells and a cell-surface molecule expressed by an effector cell to enhance effector cell activation, proliferation, survival and/or effector-cell mediated cytotoxicity. The disclosure also provides pharmaceutical compositions comprising the 5T4-binding or 4-1BB-binding polypeptide or protein molecules, nucleic acid molecules encoding these polypeptides and methods of making and using these molecules.
US10239948B2	Method of engineering multi-input signal sensitive T cell for immunotherapy The present invention relates to a method to engineer immune cell for immunotherapy. In particular said immune cells are engineered with chimeric antigen receptors, which be activated by the combination of hypoxia and ligand extracellular binding as input signals. The invention also relates to new designed chimeric antigen receptors which are able to redirect immune cell specificity and reactivity toward a selected target exploiting the ligand-binding domain properties and the hypoxia condition. The present invention also relates to cells obtained by the present method, in particular T-cells, comprising said chimeric antigen receptors for use in cancer treatments.
US10239946B2	Cell line overexpressing human CD303 antigen The invention relates to a cell line expressing the gamma chain of the FcεRI receptor and human CD303 antigen, characterized in that said cell line is transfected in a stable manner by an expression vector comprising a nucleic acid molecule coding for human CD303 antigen and having strong expression of human CD303 on the surface thereof, e.g. at least 10000 molecules of human CD303 per cell, as well as a vector or vector kit that can be used to co-express the gamma chain of the FcεRI receptor and human CD303 antigen, and different uses of the cell line of the invention.
US10239944B2	Compositions and methods related to engineered Fc constructs The present invention relates to compositions and methods of engineered IgG Fc constructs, wherein said Fc constructs include one or more Fc domains.
US10239942B2	Anti-PD-1 antibodies Antibodies that bind to programmed cell death protein 1 (PD-1), compositions comprising such antibodies, and methods of making and using such antibodies are disclosed.
US10239938B2	T-cell redirecting bispecific antibodies for treatment of disease The present invention concerns compositions and methods of use of T-cell redirecting complexes, with at least one binding site for a T-cell antigen and at least one binding site for an antigen on a diseased cell or pathogen. Preferably, the complex is a DNL™ complex. More preferably, the complex comprises a bispecific antibody (bsAb). Most preferably, the bsAb is an anti-CD3×anti-CD19 bispecific antibody, although antibodies against other T-cell antigens and/or disease-associated antigens may be used. The complex is capable of targeting effector T cells to induce T-cell-mediated cytotoxicity of cells associated with a disease, such as cancer, autoimmune disease or infectious disease. The cytotoxic immune response is enhanced by co-administration of interferon-based agents that comprise interferon-α, interferon-β, interferon-λ1, interferon-λ2 or interferon-λ3.
US10239937B2	Treatment of paroxysmal nocturnal hemoglobinuria, hemolytic anemias and disease states involving intravascular and extravascular hemolysis Methods for treating subjects having complement-mediated hemolytic disorders, such as paroxysmal nocturnal hemoglobinuria (PNH) and other hemolytic anemias, the method comprising administering an effective amount of a composition that inhibits the activity of the complement alternative pathway.
US10239936B2	Methods and compositions related to soluble monoclonal variable lymphocyte receptors of defined antigen specificity Disclosed are compositions and methods related to variable lymphocyte receptors (VLRs). More particularly, disclosed are a variety of antigen specific polypeptides, including soluble, monoclonal, and multivalent forms, as well as methods of using the polypeptides, antibodies that bind the antigen specific polypeptides, and nucleic acids, vectors and expression systems that encode the polypeptides. Antigen specific polypeptides that selectively bind pathogens, like anthrax, and carbohydrates, like blood group determinants, are specifically disclosed.
US10239933B2	Compositions and methods for modulating thrombin generation Factor V peptides and methods of use thereof are disclosed.
US10239927B2	Peptides and compositions for treatment of joint damage The present invention provides new protease resistant polypeptides, as well as compositions and methods for treating, ameliorating or preventing conditions related to joint damage, including acute joint injury and arthritis.
US10239926B2	Compositions and methods for vascular protection against reperfusion injury after myocardial ischemia As described herein, the present invention features compositions comprising an HGF/IgG complex and methods of using such compositions to reduce ischemic reperfusion injury.
US10239921B2	Insecticidal proteins Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
US10239920B2	Cupredoxin derived transport agents and methods of use thereof The present invention discloses methods and materials for delivering a cargo compound into a cancer cell. Delivery of the cargo compound is accomplished by the use of protein transduction domains derived from cupredoxins. The invention further discloses methods for treating cancer and diagnosing cancer.
US10239919B2	Selective delivery molecules and methods of use Disclosed herein is a selective delivery molecule comprising: (a) an acidic sequence (portion A) which is effective to inhibit or prevent the uptake into cells or tissue retention, (b) a molecular transport or retention sequence (portion B), and (c) a linker between portion A and portion B, and (d) at least one cargo moiety.
US10239917B2	Method for identifying novel minor histocompatibility antigens A novel method for human minor histocompatibility antigen (MiHA) discovery, novel MiHAs identified using this method, as well as uses of the novel MiHAs, are described. One of the features of the novel method is the inclusion of personalized translated transcriptome and/or exome in the database used for peptide identification by mass spectroscopy (MS). Candidate MiHAs are identified by comparing the personalized transcriptome and/or exome to a reference genome and/or to the transcriptome and/or exome of an HLA-matched subject.
US10239916B2	Controlled modulation of amino acid side chain length of peptide antigens The invention provides a method for the creation of peptide antigens comprising epitopes with at least a first modification comprising a shortened or lengthened amino acid side chain. By extension or shortening of the side chain with CH3/CH2 groups, for example, made by computer assisted modeling of the tumor antigen (peptide) bound in the MHC-I-groove, immunogenicity can be improved with minimal modification of adjacent tertiary structure, thereby avoiding cross-reactivity. Provided by the invention are methods of creating such antigens, as well as methods for therapeutic or prophylactic treatment of various conditions comprising administration of the antigens.
US10239915B2	Method for continuous production of degradation product of water-insoluble polymeric compound This invention is intended to produce a novel functional material through solubilization and molecular weight reduction of a water-insoluble polymeric compound, such as a water-insoluble protein or water-insoluble polysaccharide, in a simple and efficient manner. This invention provides a method for producing a degradation product of a water-insoluble polymeric compound comprising the steps of: bringing a water-insoluble polymeric compound into contact with a solid acid catalyst, heating the resulting mixture, and recovering a supernatant; adding an aqueous medium to the solid acid catalyst after the supernatant is recovered, agitating and heating the resulting mixture, and recovering a supernatant; washing the solid acid catalyst with an aqueous medium and recovering a wash solution; mixing the recovered supernatant with the wash solution, so as to obtain a fraction that has not adsorbed to the solid acid catalyst; and eluting an adsorbed fraction from the solid acid catalyst and recovering an eluate, so as to obtain a fraction that has adsorbed to the solid acid catalyst.
US10239913B2	Compounds and methods involving sterols Compounds and methods of synthesizing oxysterols are provided. The compounds and methods provided allow the oxysterol to be safely produced at a high yield. The compounds and methods provided can produce the oxysterol in a stereoselective manner. The method comprises reacting a diol with borane and hydrogen peroxide to form the oxysterol or a pharmaceutically acceptable salt, hydrate or solvate thereof.
US10239911B2	Beta-D-2′-deoxy-2′-alpha-fluoro-2′-beta-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment A compound of the structure: or a pharmaceutically acceptable salt or composition thereof for the treatment of a host infected with or exposed to an HCV virus or other disorders more fully described herein.
US10239909B2	Polymethine compounds with long stokes shifts and their use as fluorescent labels The present disclosure relates to new compounds and their use as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications. The labels are advantageous due to their long Stokes shifts.
US10239908B2	Cytidine-5-carboxamide modified nucleotide compositions and methods related thereto Described herein are 5-position modified cytosine nucleotides and nucleosides as well as phosphoramidites and triphosphates derivatives thereof. Further provided are methods of making and using the same, and compositions and uses of the modified nucleosides as part of a nucleic acid molecule (e.g., aptamer).
US10239905B2	Low temperature and efficient fractionation of lignocellulosic biomass using recyclable organic solid acids Methods of fractionating lignocellulosic biomass using hydrotropic sulfonic acids are provided. Also provided are methods of forming lignin particles, furans, sugars, and/or lignocellulosic micro- and nanofibrils from the liquid and solid fractions produced by fractionation process. The fractionation can be carried out at low temperatures with short reaction times.
US10239903B2	Pt (IV) derivatives and nanocarriers comprising them Provided are Pt (IV) lipophilic derivatives for improved drug performance in cancer therapy, as well as nanocarriers including the same.
US10239893B2	Controlling the isomerization rate of Azo-BF2 switches using aggregation Provided herein are photochromic organic compounds of Formula I or Formula II, which are useful as molecular switches capable of being triggered via a cis/trans isomerization process. Methods of using the molecular switch compounds to form photopharmaceutical compounds that may be used to provide selective spatiotemporal activation of pharmaceutical agents are also disclosed.
US10239890B2	Broad spectrum beta-lactamase inhibitors Broad spectrum beta-lactamase inhibitors. Certain inhibitors also exhibit potent antibiotic activity in addition to beta-lactamase inhibition. Compounds of the invention are designed such that on cleavage of the beta-lactam ring reactive moieties are generated which can inactivate beta-lactamase. Also provided are methods of making beta-lactamase inhibitors and beta-lactam antibiotics exhibiting such inhibition. Additionally provided are pharmaceutical compositions for treatment or prevention of bacterial infections and methods of treatment of such infections.
US10239885B1	Compound 1-[2-[4-(2-ethyl-6,8-dimethylimidazo[1,2-α]pyrazin-3-yl)phenyl]ethyl]-3-(p-tolylsulfonyl)urea as a prostaglandin EP4 receptor antagonist The present invention describes novel compounds, or veterinary or pharmaceutically acceptable salts thereof, veterinary or pharmaceutical compositions thereof, and medical uses thereof. The compounds of the invention have activity as prostaglandin EP4 receptor antagonists and are useful in the treatment or alleviation of pain, inflammation and inflammation-associated disorders. Also described herein are methods for treating pain by administering the compounds of the invention. For example, the invention describes 1-[2-[4-(2-ethyl-6,8-dimethylimidazo[1,2-a]pyrazin-3-yl)phenyl]ethyl]-3-(p-tolylsulfonyflurea of the formula: veterinary or pharmaceutical compositions thereof, and methods of treatment using the subject compound and compositions thereof.
US10239884B2	Coelenterazine compounds and uses thereof There is provided a series of coelenterazine (CTZ) derivatives as a substrate with high luminescence intensity, which is optimal for maximum luminescence wavelengths at both 400 nm (blue-shifted RLuc luminescence system) and 500 nm (ALuc luminescence system) for bioassays which is more sensitive than known techniques. The novel CTZ derivatives are compounds in which a specific position(s) of the CTZ is/are substituted with a specific substituent(s) as shown, for example, by the Formula [I], and has a higher luminescence intensity than known CTZ derivatives in blue-shifted RLuc luminescence system or ALuc luminescence system.
US10239883B2	4-imidazopyridazin-1-yl-benzamides as BTK inhibitors The present invention relates to 6-5 membered fused pyridine ring compounds according to Formula (I) or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6-5 membered fused pyridine ring compounds according to Formula (I) in the treatment of Bruton's Tyrosine Kinase (Btk) mediated disorders.
US10239880B2	Cyclopenta[d]pyrimidines and substituted cyclopenta[d]pyrimidines as antitubulin and microtubule targeting agents, monocyclic pyrimidines as tubulin inhibitors, and pyrrolopyrimidines as targeted antifolates and tubulin and multiple receptor tyrosine kinase inhibition and antitumor agents The present invention provides a compound of Formula I, and salts thereof, and a pharmaceutical composition comprising a compound of Formula I: wherein R1 is selected from the group consisting of and R2 is an alkyl group having from one to ten carbon atoms, or wherein R2 is selected from the group consisting of R1 is an alkyl group having from one to ten carbon atoms; and R is H, or an alkyl group having from one to ten carbon atoms, and R3 is H, an alkyl group having from one to ten carbon atoms, or a halogen. Preferably the compound of Formula V includes wherein R3 is a halogen, and most preferably wherein the halogen is chlorine. Methods of treating a patient with cancer with these compounds are also provided.
US10239879B2	Process for producing purinone derivative According to the present invention, differently from well-known production methods, with the use of a different starting material, Ullmann condensation which may decrease the yield with an increase of a production scale can be avoided and thus 6-amino-9-[(3R)-1-(2-butynoyl)-3-pyrrolidinyl]-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one can be provided safely and stably with high reaction yield.
US10239877B2	Pharmacophore for trail induction There are disclosed imidazolinopyrimidinone compounds that have activity to induce TRAIL gene expression in macrophages. There is further disclosed a method for treating various cancers comprising administering effective amounts of an imidazolinopyrimidinone having the structure of Formula I herein. The invention is directed, in various embodiments, to a compound and pharmaceutical composition comprising an effective amount of a compound capable of inducing expression of TRAIL gene in cells capable of expressing the TRAIL gene to produce the cytokine TRAIL.
US10239867B2	Modulators of ATP-binding cassette transporters Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
US10239866B2	Selective methods for the separation of ondansetron and related impurities The present disclosure generally relates to methods for separating ondansetron and related impurities using CO2-based chromatography.
US10239865B2	Bisphenols containing pendant clickable maleimide group and polymers therefrom The patent discloses bisphenol monomers of formula I with pendant maleimide group connected via alkylene spacer and preparation thereof. Also, it discloses polymers based on bisphenol monomers containing pendant clickable maleimide group. Further, it provides a process for the preparation of polymers possessing pendant clickable maleimide groups based on bisphenols containing pendant maleimide group. Formula (I) wherein, x is an integer selected from 0 to 10.
US10239861B2	Therapeutic compounds and uses thereof The invention relates to compounds of formula (I) and salts thereof: wherein R1-R3 have any of the values defined in the specification. The compounds and salts are useful for treating PCAF mediated disorders and/or GCN5 mediated disorders. The invention also provides pharmaceutical compositions comprising a compound of formula (I), or a pharmaceutically acceptable salt thereof, as well as and methods of using said compounds, salts, or compositions in the treatment of various disorders.
US10239856B2	Synthesis of resorcylic acid lactones useful as therapeutic agents Disclosed are macrocyclic compounds of formulae I, I′, II, II′, III, III′, IV, and V, which are analogs of the pochonin resorcylic acid lactones, pharmaceutical compositions comprising the compounds, and methods and uses comprising the compounds for the treatment of diseases mediated by kinases and Heat Shock Protein 90 HSP90.
US10239854B2	Compounds, compositions and methods for treating or preventing a symptom associated with gout or hyperuricemia The inventive subject matter provides compounds, compositions and methods for lowering serum acid (sUA) for the treatment of gout, and having reduced liver toxicity, associated with CYP2C9 metabolic pathway.
US10239852B2	Process for the production of 5-hydroxymethylfurfural in the presence of organic catalysts from the thiourea family A process for the transformation of a feed of at least one sugar into 5-hydroxymethylfurfural, contacting the feed with one or more organic catalysts in the presence of at least one solvent, said solvent being water or an organic solvent, alone or as a mixture, at a temperature in the range 30° C. to 200° C., and at a pressure in the range 0.1 MPa to 10 MPa, in which said organic catalysts are selected from compounds from the thiourea family with general formula R1NH—C(═S)—NHR2, in which the groups R1 and R2 are aromatic groups optionally having a heteroatom, linear or branched alkyl groups, which may or may not be cyclic, and alkyl groups with at least one heteroatom, which may be linear or branched, which may or may not be cyclic, said groups R1 and R2 possibly being substituted or unsubstituted and which may be identical or different.
US10239851B2	Carboxylic acid derivatives and use thereof in the preparation of prodrugs The present invention discloses a class of carboxylic acid derivatives and use thereof in preparation of prodrugs. The carboxylic acid derivatives have the general formula (I), wherein R1 is H or alkyl; X is H or F; Y is F or fluoroalkyl; n is 0, 1, 2, 3, 4, 5, or 6; W is W1 or W2; W1 is NR2R3, NR2R3.A, R2 and R3 are each independently H, alkyl, cycloalkyl, or a protecting group for amino; m is 0, 1, 2, or 3; A is an acid; W2 is COOR4, OPO(OR4)2, or PO(OR)2; R4 is H, or a protecting group for carboxyl or hydroxyl in phosphoric acid.
US10239846B2	Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.
US10239842B2	Hydrosoluble compounds derived from benzimidazole used in treating fasciolosis The present invention relates to hydrosoluble compounds derived from benzimidazole represented by general formula I: wherein: Y1 e Y2 are independently O or S, and at least one of Y1 and Y2 is O; R1 and R2 are independently hydrogen or a cation, both are hydrogen or both are cations; R3 is a C1-4 alkyl; R4 and R5 are independently halogen or a —OR6 alkoxide; R6 is C6-C10 aryl linked in 5- or 6-position of benzimidazole nucleus.
US10239839B2	Compounds and formulations suitable for radical scavenging The present invention relates to compositions and methods of using free radical scavengers with reduced 1O2 generation. In certain embodiments, these compositions and methods of use relate to fullerene-derived ketolactams and fullerene-derived ketolactam derivatives, fullerene derivatives, and/or fullerenes. In yet other embodiments, the invention relates to cosmetic or dermatological compositions comprising said free radical scavengers with reduced 1O2 generation.
US10239831B2	Method for producing bis(3-aminophenyl)disulfides and 3-aminothiols The present invention relates to a novel method for preparing bis(3-aminophenyl) disulphides of the general formula (I) and 3-aminothiols of the general formula (II), where X,Y have the meanings stated in the description, which serve as intermediates for the preparation of phenyl sulphoxides having insecticidal, acaricidal and nematicidal activity.
US10239829B2	Antagonists of the glucagon receptor The present invention provides for novel compounds of Formula (I) and pharmaceutically acceptable salts and co-crystals thereof which have glucagon receptor antagonist or inverse agonist activity. The present invention further provides for pharmaceutical compositions comprising the same as well as methods of treating, preventing, delaying the time to onset or reducing the risk for the development or progression of a disease or condition for which one or more glucagon receptor antagonist is indicated, including Type I and II diabetes, insulin resistance and hyperglycemia. The present invention also provides for processes of making the compounds of Formula I, including salts and co-crystals thereof, and pharmaceutical compositions comprising the same.
US10239825B2	Ketamine derivatives The present invention relates to ketamine derivatives of the formula (I), pharmaceutical compositions comprising them, and methods for treating pain comprising administering them, and their use in the manufacture of medicaments for treating pain. The present invention also relates to methods for anaesthetizing and methods for sedating a subject comprising administering ketamine derivatives of the formula (II).
US10239824B2	Automated synthesis of small molecules using chiral, non-racemic boronates Provided are methods for making and using chiral, non-racemic protected organoboronic acids, including pinene-derived iminodiacetic acid (PIDA) boronates, to direct and enable stereoselective synthesis of organic molecules. Also provided are methods for purifying PIDA boronates from solution. Also provided are methods for deprotection of boronic acids from their PIDA ligands. The purification and deprotection methods may be used in conjunction with methods for coupling or otherwise reacting boronic acids. Iterative cycles of deprotection, coupling, and purification can be performed to synthesize chiral, non-racemic compounds. The methods are suitable for use in an automated chemical synthesis process. Also provided is an automated small molecule synthesizer apparatus for performing automated stereoselective synthesis of chiral, non-racemic small molecules using iterative cycles of deprotection, coupling, and purification.
US10239822B2	Process for the separation of long chain amino acids and dibasic acids There is disclosed a process for the separation of long chain dibasic acid and fatty acid, comprising: (1) reacting a mixture of long chain dibasic acid and fatty acid with ammonium hydroxide to form an insoluble ammonium salt of fatty acid and a soluble ammonium salt of long chain dibasic acid; (2) recovering the insoluble ammonium salt of fatty acid; and (3) adding an acid to the mother liquor of step (2) to obtain the long chain dibasic acid.
US10239820B2	Etheramine compounds Embodiments described herein provide a compound that may be used in a variety of applications such as corrosion inhibition, additives for metalworking, mining reagents, epoxy curatives, emulsifiers, fuel or lubricant additives, surfactant manufacture, acid scavengers and asphalt additives. The compound has the following structure: where R1 is a methoxy group, R2, R3, R4 and R5 are independently a hydrogen atom or an alkyl group, and R6 is an aminomethyl group.
US10239818B2	Method for producing diesters of terephthalic acid with circulation of the reaction mixture The present invention relates to a process for preparing a terephthalic diester by reacting terephthalic acid with at least one alcohol, wherein terephthalic acid is suspended in the alcohol in a dispersing tank, the preliminary suspension is passed from the dispersing tank into a reactor and converted in the presence of an esterification catalyst, a reaction suspension is drawn off from a region between the upper region and the lower region of the reactor, a first stream of the reaction suspension is recycled into the upper region of the reactor and a second stream of the reaction suspension is introduced into the lower region of the reactor, and the reaction suspension is thus mixed, wherein the stream drawn off and/or the first stream is passed through a heat exchanger outside the reactor and heated; and water of reaction is distilled off together with the vapor as alcohol-water azeotrope, the vapor is at least partly condensed, the condensate is separated into an aqueous phase and an organic phase and the organic phase is at least partly recycled into the reaction system.
US10239817B2	Process for the preparation of (1R,3R)- and (1S,3S)-2,2-dihalo-3-(substituted phenyl)cyclopropanecarboxylic acids The (1R,3R)- or (1S,3S)-enantiomer of 2,2-dichloro-3-(substituted phenyl)cyclopropane-carboxylic acid is prepared in a process involving chemical resolution of a racemic mixture of a trans-2,2-dichloro-3-(substituted phenyl)cyclopropanecarboxylic acid with an enantiomeric amine, isolation of a diastereomeric amine salt and finally treatment of the salt with an acid.
US10239815B2	Method for producing acrylic acid The objective of the present invention is to provide a method for efficiently producing acrylic acid while troubles not only in a waste oil handling after distillation of acrylic acid but also in a purification system of acrylic acid during distillation are reduced. The method for producing acrylic acid according to the present invention is characterized in comprising the step of supplying at least crude acrylic acid and an alcohol solvent to an acrylic acid distillation apparatus to distill acrylic acid, wherein a boiling point of the alcohol solvent is higher than a boiling point of acrylic acid by not lower than 50° C.
US10239809B2	Methods for preparing bridged bi-aromatic ligands New methods of preparing bridged bi-aromatic ligands are disclosed. The methods employ direct di-ortho-lithiation of aromatic rings of bridged protected bi-aromatic diphenols. The ligands may be used to prepare transition metal compounds useful as catalysts in olefin polymerization.
US10239806B2	Continuous solid-state separation device and process for producing fuel ethanol The present invention belongs to the technology field of microbial fermentation of the sugar-containing raw materials for producing fuel ethanol. It specifically relates to a continuous separation device and process for producing fuel ethanol. The device is continuous distillation device, and is improvement of the distillation device in the prior art. The present invention utilizes a continuous ethanol separation process, which can make full use of fermentable sugar of the sweet sorghum straw (or sugar cane, sugar beet), increase ethanol yield, change the traditional mode of production, truly realize continuous ethanol separation process; and the waste materials produced in the procedure of distillation can be used either as fuel, or as animal feed, and this not only saves the cost, but also is greatly significant in environmental protection.
US10239805B2	Stable compositions of trifluoroethylene The present invention relates to a composition comprising trifluoroethylene and 1,2,3,3,3-pentafluoropropene characterized that the weight ratio trifluoroethylene/1,2,3,3,3-pentafluoropropene is from 5/95 to 95/5.
US10239801B2	Hydrogen rejection in methanol to hydrocarbon process with bifunctional catalyst The present application relates to a process for production of hydrocarbons comprising the steps of: converting a feed stream comprising alcohols, ethers or mixtures hereof over a Zn-containing zeolite based catalyst wherein Zn is at least partly present as ZnAl2O4, active in dehydrogenation of hydrocarbons, in a conversion step thereby obtaining a conversion effluent, separating said effluent to obtain an aqueous process condensate stream, a liquid hydrocarbon stream and a gaseous stream, removing part of the hydrogen formed in the conversion step, and recycling at least part of the gaseous and/or liquid hydrocarbon stream to the conversion step.
US10239793B2	Melted product with a high zirconium content A fused-cast refractory product including, as mass percentages on the basis of the oxides and for a total of 100% of the oxides: ZrO2+HfO2: remainder to 100%, with HfO2≤5%; SiO2: 1.5% to 7.5%; Al2O3: 1.0% to 3.0%; CaO+SrO: 1.2% to 3.0%; Y2O3: 1.5% to 3.0%; Na2O+K2O: <0.15%; B2O3: <1.0%; P2O5: <0.15%; Fe2O3+TiO2: <0.55%; oxide species other than ZrO2, HfO2, SiO2, Al2O3, Na2O, K2O, B2O3, CaO, SrO, Y2O3, P2O5, Fe2O3 and TiO2: <1.5%.
US10239792B2	Method of preparing ceramic powders A method of forming composition-modified barium titanate ceramic particulate includes mixing a plurality of precursor materials and a precipitant solution to form an aqueous suspension. The plurality of precursors include barium nitrate, titanium chelate, and a metal or oxometal chelate. The precipitant solution includes tetraalkylammonium hydroxide and tetraalkylammonium oxalate. The method further includes treating the aqueous suspension at a temperature of at least 150° C. and a pressure of at least 200 psi, and separating particulate from the aqueous suspension after treating.
US10239788B2	Self-healing composite of thermoset polymer and programmed super contraction fibers A composition comprising thermoset polymer, shape memory polymer to facilitate macro scale damage closure, and means for molecular scale healing has the ability to repair structural defects by a bio-mimetic, close-then-heal process. The shape memory polymer serves to bring surfaces of a structural defect into proximity, after which the healing means moves into the defect and provides molecular scale healing. The means for molecular scale healing can be a thermoplastic, such as fibers, particles or spheres, which are heated to or above the thermoplastic's melting point, and then the composition is cooled below that melting temperature. The compositions can not only close macroscopic defects, but they can also do so repeatedly even if damage recurs in a previously healed/repaired area.
US10239785B2	Activated pulverised glass as an additive for mortars and cement, and related cementitious products The present invention relates to a cementitious composition adapted to form mortars or cements comprising glass as an additive having reduced tendency to reaction with alkali, characterized in that said glass is obtained by grinding and subsequent washing with water.
US10239784B2	Deep non-frangible stress profiles and methods of making A non-frangible glass article strengthened by a dual or two-step ion exchange (IOX) process, where the first IOX step leads to a depth of compressive layer FSM_DOL>0.1·t or, in some embodiments, FSM_DOL>0.15·t, where t is the thickness of the glass, is provided. The glass article has a compressive stress CS1 after the first IOX step at the surface of from 100 MPa to 400 MPa or, in some embodiments, from 150 MPa to 300 MPa. The first IOX step is followed by a second IOX step, leading to a “spike” compressive stress CS2 after the second IOX step at the surface of greater than 500 MPa or, in some embodiments, 700 MPa. The width of the spike generated by the second IOX is between 1 μm and 30 μm, or between 8 μm and 15 μm, using the criteria where the magnitude (absolute value) of the slope of the spike is higher than 20 MPa/μm.
US10239781B2	High modulus glass fibre composition, and glass fibre and composite material thereof The present invention provides a high-modulus glass fiber composition, a glass fiber and a composite material therefrom. The glass fiber composition comprises the following components expressed as percentage by weight: 55-64% SiO2, 13-24% Al2O3, 0.1-6% Y2O3, 3.4-10.9% CaO, 8-14% MgO, lower than 22% CaO+MgO+SrO, lower than 2% Li2O+Na2O+K2O, lower than 2% TiO2, lower than 1.5% Fe2O3, 0-1.2% La2O3, wherein the range of the weight percentage ratio C1=(Li2O+Na2O+K2O)/(Y2O3+La2O3) is greater than 0.26. Said composition can significantly increase the glass elastic modulus, effectively inhibit the crystallization tendency of glass, decrease the liquidus temperature, secure a desirable temperature range (ΔT) for fiber formation and enhance the fining of molten glass, thus making it particularly suitable for production of high-modulus glass fiber with refractory-lined furnaces.
US10239780B2	High strength glass-ceramics having petalite and lithium silicate structures Glass and glass ceramic compositions having a combination of lithium silicate and petalite crystalline phases along with methods of making the glass and glass ceramic compositions are described. The compositions are compatible with conventional rolling and float processes, are transparent or translucent, and have high mechanical strength and fracture resistance. Further, the compositions are able to be chemically tempered to even higher strength glass ceramics that are useful as large substrates in multiple applications.
US10239773B2	Systems for microorganism sustenance in an activated sludge unit The present disclosure relates generally to processes and systems for maintaining a live culture of microorganisms in the activated sludge unit of a refinery during an extended refinery shut-down.
US10239770B2	Multi-stage submerged membrane distillation water treatment apparatus A multi-stage submerged membrane distillation water treatment apparatus including: a plurality of raw water tanks arranged in multiple stages ranging from a first stage to an n-th stage and storing raw water, the raw water flowing sequentially from the first stage to the n-th stage; membrane distillation (MD) modules submerged in the respective raw water tanks and discharging a portion of the raw water as vapor; heat exchangers submerged in the respective raw water tanks and maintaining the raw water at a predetermined temperature by performing heat exchange between the raw water and vapor supplied from the respective previous-stage MD modules; a vapor generator generating and supplying high-temperature vapor to the first-stage heat exchanger; a condenser condensing vapor supplied by the n-th-stage MD module; and a raw water feeder feeding low-temperature raw water to the first-stage raw water tank via the condenser.
US10239769B2	System and method for treating contaminated wastewater A process for treating contaminated wastewater that includes flowing the contaminated wastewater into at least one pre-pond solids filter tank comprising sand; flowing the contaminated wastewater from at least one pre-pond solids filter tank into at least one sedimentation pond; flowing the contaminated wastewater from the at least one sedimentation pond into at least one filter tank including sand and a mixture of sand and zero-valent iron; and discharging treated wastewater from the at least one filter tank.
US10239768B2	Method and system for de-oiling a feed of oil and water A method and system for de-oiling a feed comprising oil and water. The feed has an input temperature above the boiling point of water and an input pressure sufficient to maintain the water in a liquid state. In at least one embodiment, the method comprises pumping the feed with a motive pump through a phase separator having a restriction to effect a phase separation of oil and water in the feed and produce an agitated mixture, supplying the agitated mixture from the phase separator into a pressure vessel operating at a pressure sufficient to maintain in a liquid state water that is at a temperature above the boiling point of water, removing an oil phase from the pressure vessel, and removing a water phase from the pressure vessel.
US10239762B2	Power plant for producing energy and ammonia The present disclosure relates to power plants. The teachings thereof may be embodied in processes for producing ammonia and energy, e.g., a method for producing ammonia and energy comprising: spraying or atomizing an electropositive metal; burning the metal with a reaction gas; mixing the reacted mixture with water; separating the mixture into (a) solid and liquid constituents and (b) gaseous constituents; at least partially converting energy of the solid and liquid constituents and of the gaseous constituents; and separating ammonia from the gaseous constituents. Mixing the reacted mixture may include spraying or atomizing the water or the aqueous solution or the suspension of the hydroxide of the electropositive metal into the reacted mixture.
US10239760B2	Method for producing zeolite There is provided a method for producing a zeolite more excellent in moisture absorption characteristics. The method includes physically pulverizing a zeolite that has a gradient of a Na/Si value from a surface of the zeolite in a depth direction, that has a proportion of the Na/Si value at a depth of 10 nm from the surface to the Na/Si value at the surface of 90% or more, and that has a proportion of the Na/Si value at a depth of 30 nm from the surface to the Na/Si value at the surface of 70% or more, the Na/Si value representing a composition ratio between Na and Si, and crystallizing the physically pulverized zeolite.
US10239757B2	Nanostructured silicon nitride synthesis from agriculture waste A method of making Si3N4 nanotubes and nanorods comprising adding agricultural husk material powder to a container, wherein the container is a covered boron nitride crucible, creating an inert atmosphere of nitrogen inside the container, applying heat, heating the agricultural husk material, and reacting the agricultural husk material and forming silicon nitride, wherein the silicon nitride is nanotubes and nanorods.
US10239756B1	Process for sulfur recovery from acid gas stream without catalytic Claus reactors A method to recover sulfur from hydrogen sulfide in an acid gas stream comprising the steps of reacting the hydrogen sulfide and oxygen in the combustion furnace, transferring heat from the furnace effluent to produce a boiler effluent, reducing the temperature of the boiler effluent in the sulfur condenser, separating the water vapor from the non-condensed gases stream, reacting the sulfur dioxide and the hydrogen gas to produce hydrogen sulfide in the first hydrogenation reactor, reacting the hydrogen sulfide and oxygen in the reactor furnace to produce a reactor effluent, transferring heat from the reactor effluent to produce a cooled effluent, reducing the temperature of the cooled effluent in the sulfur cooler to produce a gases stream, separating the water vapor from the gases stream, reacting the sulfur dioxide and the hydrogen gas to produce hydrogen sulfide in the second hydrogenation reactor to produce a treated tail gas stream.
US10239749B2	Systems and methods for MEMS-based cross-point electrical switching An electrical cross-point switch N inputs, each at least 10 Gbps, connected to input transmission lines; M outputs, each at least 10 Gbps, connected to output transmission lines; at least two Radio Frequency (RF) Microelectromechanical systems (MEMS) switches selectively interconnecting each input transmission line and each output transmission line; and control and addressing circuitry configured to selectively control interconnection of each input transmission line and each output transmission line via the at least two RF MEMS switches. The at least two RF MEMS switches can be embedded in each input transmission line and each output transmission line. The input transmission lines and the output transmission lines can each be partially shielded microwave transmission lines.
US10239747B2	Semiconductor pressure sensor A semiconductor pressure sensor includes a fixed electrode placed at a principal surface of a semiconductor substrate, and a diaphragm movable through an air gap in a thickness direction of the semiconductor substrate at least in an area where the diaphragm is opposed to the fixed electrode. The diaphragm includes: a movable electrode; a first insulation film placed closer to the air gap with respect to the movable electrode; a second insulation film placed opposite to the air gap with respect to the movable electrode, the second insulation film being of a same film type as the first insulation film; and a shield film that sandwiches the second insulation film with the movable electrode.
US10239745B2	Fueling station sump dehumidifying system Systems and methods for preventing biocorrosion of fuel handling components located in a sump in a fuel dispensing environment. One method includes exposing a hygroscopic material to moisture-laden air in the sump such that the hygroscopic material deliquesces into a liquid solution and exposing a buffer material to ethanol-blended fuel vapors in the sump. The method also includes collecting the liquid solution in a reservoir and monitoring the level of the liquid solution in the reservoir using a liquid level sensor. Further, the method includes notifying service personnel of the level of the liquid solution in the reservoir.
US10239742B2	Semi-automated beverage dispensing machines and methods Food product dispensing machines and methods for dispensing food product into a cup. The food product dispensing machine includes a cup holder having a target element, a sensor that senses the target element, and a controller. The cup holder is configured to hold a cup such that the cup prevents the sensor from sensing at least a portion of the target element. The controller determines whether a cup is present in the cup holder and/or a size of the cup based on a remaining portion of the target element that is sensed by the sensor when the cup is held by the cup holder. Drive mechanisms are configured to move the first and second cup holders along first and second radial paths, respectively, with respect to the common dispensing position. An indicator is configured to indicate a remaining number of cup dispenses to the user.
US10239741B2	Suspension-type stacker crane A suspension stacker crane includes an upper truck frame, a pair of mast units, a transferring device, and an upper base. The upper truck frame includes driving trucks arranged side by side in a travelling direction, and a bogie structure that couples the driving trucks. Each of the pair of mast units is suspended from the bogie structure, and includes a lifting drive motor and a lifting drive transmission. The pair of mast units is arranged side by side in the travelling direction. The transferring device is driven to be lifted or lowered by the lifting drive motor and the lifting drive transmission. The upper base links the pair of mast units.
US10239733B2	Flange lifting tool The invention relates to a lifting tool for lifting or upending a flanged object, the lifting tool extending along a central longitudinal tool axis and comprising; a hoisting member for coupling the lifting tool to a hoisting line and applying a hoisting force to the lifting tool, a main frame for guiding a moveable flange engagement member, said flange engagement member moveably coupled with the main frame for supporting the flanged object, and moveably with respect to the main frame, a driving device coupled with the flange engagement member and the main frame for driving the flange engagement member radially with respect to the central longitudinal tool axis between a flange releasing position for introducing the lifting tool at least partly in said flanged object and past the flange thereof and a flange supporting position wherein the flange engagement member supports the object, wherein the driving device comprises a linkage system coupled with the hoisting member and the flange engagement member such that the flange engagement member is forced towards its flange supporting position upon application of the hoisting force to the lifting tool.
US10239728B2	Intelligent building system for providing elevator occupancy information with anonymity A system and/or method for detecting an occupancy of an elevator cab of an elevator to generate occupancy information is provided. The system and/or method further generates anonymized occupancy information based on the occupancy information and provides the anonymized occupancy information to enable the occupancy of the elevator cab to be presented with anonymity for occupants.
US10239727B2	Method and arrangement for control and evaluation of the operation of a lift An automated method to control and evaluation of the operation of a lift installation, where at least one load of unknown weight is weighed by means of a weighing machine; the sum of the weights detected on site in the lift installation where the maintenance work is being performed is transmitted to a portable control console, which transmits the sum of the weights detected associated with the loads introduced to the lift cabin to a load weighing device; to receive command signals associated with the control and maintenance tasks transmitted from the portable control console, in response to operating parameters of the lift cabin loaded with the sum of the weights detected.
US10239712B2	Terminal for transfer of dry, flowable, granular materials A transfer terminal is shown for off-loading dry, flowable, granular material from large transportation vehicles such as trucks or barges to smaller transport trucks. A pouch within a tank is provided for receiving the material, which material is distributed to storage silos. A single elevator is used to load the pouch and all storage silos. By aeration of the materials, a very low angle of repose is created for the material, which allows the material to flow at a very low angle, both to and from the various silos. Material being loaded into a transport truck flows through the pouch.
US10239710B2	Method and device for loading a pallet A method for loading a pallet with different individual packs of a picked order includes a first method step in which the individual packs to be palletized are delivered in a conveyor cart, a second method step in which the individual packs are separated, positioned and prepared for palletizing in such a way that a palletizing station has access to all of the individual packs and a third method step in which the individual packs are picked in a sequence predetermined by the palletizing station and stacked on the pallet. A device for performing the method includes one or more palletizing stations with a storage device for the individual packs and with a continuous conveying loop acting as a conveying path for the conveyor cart.
US10239708B2	Laboratory sample distribution system and laboratory automation system A laboratory sample distribution system in which a sample container carrier can be centered at a specific position is presented. A laboratory automation system with such a laboratory sample distribution system is also presented.
US10239703B2	Board turner A board turner assembly may include an endless chain, first and second groups of turning arms pivotably coupled with the endless chain and disposed along opposite sides thereof, an upper guide with an inclined surface, an actuator selectively operable to move the upper guide between a resting position and an extended position, and one or more endless belts. The turning arms may be spaced apart at regular intervals that are offset on one side of the chain relative to the other. The groups of turning arms may be operated in an alternating fashion to turn selected boards to a desired orientation (e.g., wane side up). Corresponding methods and systems are also described.
US10239701B2	Conveyor screening during robotic article unloading A robotic material handling system has a controller that positions a nose conveyor surface proximate to an article pile, uses a robotic manipulator to robotically move one or more articles per operation onto the nose conveyor from the article pile, and receives a scan of the nose conveyor surface to detect respective locations of any articles received on the nose conveyor surface. The controller determines whether the respective locations of any scanned articles prevent immediate rearward conveyance by the two or more parallel conveyors at a first speed. If so detected, the controller causes at least one of the two or more parallel conveyors to operate at the first speed and at least another one of two or more parallel conveyors to operate at a second speed that is not equal to the first speed so that cartons do not jam or overwhelm a narrower rearward conveyor.
US10239695B2	Conveyor belt A conveyor belt includes an upper cover rubber and a lower cover rubber disposed above and below a core layer; and a protective fiber layer made from high strength fiber disposed at least in a central portion of the upper cover rubber in a belt width direction and extending continuously in a belt longitudinal direction; an elastic modulus E of the protective fiber layer in the belt longitudinal direction being a low elastic modulus E1 equal to or less than a predetermined value when a tension in the belt longitudinal direction acting on the conveyor belt is equal to or less than a setting tension Ts, and being a high elastic modulus E2 higher than the low elastic modulus E1 when a predetermined high tension higher than the setting tension Ts is acting on the conveyor belt.
US10239692B2	Article transport facility A transport vehicle controller causes a travel speed of the corresponding one of the plurality of article transport vehicles to which the transport vehicle controller is provided to be reduced based on position information of corresponding one of the plurality of article transport vehicles to which the transport vehicle controller is provided and the position information on another of the plurality of article transport vehicles if a separation distance between the corresponding one of the plurality of article transport vehicles to which the transport vehicle controller is provided and the another of the plurality of article transport vehicles is less than, or equal to, a set separation distance.
US10239685B2	Spray delivery device A spray delivery system including a sprayable active agent composition housed within a container is provided that can be used in the treatment of various skin conditions. The composition includes a hydrofluoro-based propellant, a carrier fluid, and active agent particles, and has a viscosity ranging from about 500 centipoise to about 10,000 centipoise. The container includes a dip tube; a valve assembly that includes a valve body, a stem comprising a stem orifice, and a vapor tap; and an actuator. The dip tube is coupled to the actuator by the valve assembly, and the actuator is depressed to dispense the emulsion. By selectively controlling the components and viscosity of the composition and the dimensions of the container components, the active agent particles resist settling so a substantially homogeneous distribution of the particles is maintained. Thus, the composition can be evenly dispensed from the container as a fine mist without clogging.
US10239675B2	Integrated product scoop or dispenser holder or clip, methods of production and uses thereof An integrated product scoop or dispenser holder arrangement is disclosed and described in detail that includes: a) a container for retaining product, wherein the container comprises a body component having an interior surface, an exterior surface, a top, a bottom, an opening in or near the top of the container and a lid, b) a product retained in the container, c) an integrated product scoop or dispenser holder that is physically integrated into the material used to form the container, is located as a part of the interior surface of the container, and is designed to hold or retain a scoop or dispenser, and d) a scoop or dispenser that releasably mates with the integrated product scoop or dispenser holder in order to form the integrated product scoop or dispenser holder arrangement.
US10239669B2	Cup lid A reusable lid includes a main body, a spout portion, and a sealing member. The main body has a first surface. The spout portion extends outwardly from the first surface of the main body and has a second surface that is substantially parallel to the first surface and has an opening formed therein. The sealing member has a base portion, a cap portion with a third surface, and an intermediate portion disposed between the base portion and the cap portion. The sealing member is movable relative to the main body and the spout portion between a first orientation and a second orientation. In the first orientation, the cap portion engages the second surface to seal the opening and the third surface is substantially parallel to the first and second surfaces, and in the second orientation, the opening is unobstructed by the cap portion and the third surface is non-parallel to the first and second surfaces.
US10239665B2	Sanitizing pouch for electronics The present invention is an elastic (mechanically stretchable), sanitizing pouch configured to receive and hold an Electronic Device of a predetermined configuration. The elasticity of the fabric used maximizes surface contact with the Electronic Device and the closeness of the fabric of the invention with the outside surfaces of the Electronic Device. A liftable and removable cover flap on the front of the invention is used to hold and access the inside of the invention. The back of the invention includes at least one pocket. The invention further includes a pull tab to help lift an Electronic Device out of the invention. While inside the invention, the silver ions are released in the fabric and inhibit the colonization of bacteria, viruses and fungus on the Electronic Device.
US10239664B2	Bottom-gusseted package and method A bottom-gusseted package comprises a package body, and a bottom gusset positioned transversely of a longitudinal axis of the package body. Formation of the bottom-gusseted package is effected by positioning individual sleeves transversely of the longitudinal axis of a flexible web which forms the package body. During package formation, the flexible web is cut to form individual packages, with each individual sleeve positioned to form a bottom gusset in a respective package. Optionally, the individual sleeve portions can be configured such that when the flexible web is cut to form individual packages, and each individual sleeve is be cut to form a bottom gusset in one package, and a top sleeve portion in an adjacent package.
US10239662B2	Height-adjustable container A height-adjustable container is configured such that an upper body and a lower body thereof are rotated from side to side in a zigzag form while coming into close contact with each other, so that the height of the container can be easily adjusted. The present invention enables the height of a container to be adjusted, whereby it is possible to make better use of a space of a refrigerator, a cabinet, or the like, in which the container is stored.
US10239656B2	Bulk bin side wall retention A bulk bin container having a retention clip for blocking both a first and second pin of a hinge axis element is provided. The container includes a generally rectangular base having one or more upward wall extensions along the edges of the base where each extension includes a plurality of hinge pockets for receiving a hinge axis element from the side walls. The retention clips connect to the base for blocking both the first hinge pin and the second hinge pin of the hinge axis element.
US10239650B2	Packaging boxes with centring tab, cutouts and set of cutouts, method and device for producing such boxes A packaging box, cutouts, method and device for producing corrugated cardboard boxes comprising walls, a base (6) and a cover (7), the inner face of the base being provided with at least two recesses (33) and the cover comprising at least two tabs (38) adhered to the upper face thereof, directly above the recesses of complementary shape. The recesses and/or the tabs are situated fully inside the corresponding face or faces (31, 32).
US10239648B2	Apparatus and method for forming a cup with a reformed bottom An apparatus and method of forming a metallic cup that is subsequently reformed into a container body. More specifically, an apparatus and methods used to form a metallic cup with a reformed bottom having an inwardly oriented projection are disclosed. The inwardly oriented projection reduces a height of the metallic cup but utilizes the same amount of metallic stock material as a taller cup with substantially the same diameter that does not have an inward projection. The inwardly oriented projection thus allows the use of a conventional bodymaker and other can manufacturing tools to convert the cup into a container body of a preferred size and shape.
US10239646B2	Glove picking, organizing, and stacking apparatus Provided is a glove picking, organizing, and stacking apparatus, belonging to the field of equipment for producing PVC, nitrile, and latex gloves, and comprising a glove-picking apparatus (2), a correcting conveying apparatus, a conveying and placing apparatus, and a front/back stacking, conveying, and taking apparatus; the glove-picking apparatus (2) is connected to the front/back stacking, conveying, and taking apparatus by means of the correcting conveying apparatus or the conveying and placing apparatus; a system control apparatus is connected to the described apparatuses and controls their switching and operation, thereby automatically carrying out the entire process of picking, transporting, stacking, and counting the gloves, and the quality of and efficiency in the completion of the tasks is very high.
US10239639B2	Launch tube restraint system for unmanned aerial vehicle (UAV) An unmanned aerial launch vehicle (UAV) launch apparatus is disclosed that includes a UAV having an exterior surface, an aerial vehicle (AV) tab extending from the exterior surface, a tube containing the UAV, the tube including a tab stop configured to controllably hinder travel of the AV tab past the tab stop, and a pair of opposing tab guides configured to position the AV tab for travel over the tab stop.
US10239637B2	System and method for arresting and neutralizing unmanned vehicles The use of shielded material in a deployable vehicle arresting and containment device that, when used for the interception of an unmanned vehicle, effectively achieves RF isolation of that vehicle, breaking all external communications with that vehicle. This apparatus, which may have internal and external antennas, could enable a variety of advanced effects such as localized GPS and command and control link spoofing and jamming as well as providing a vehicle for signal intercept and intelligence solutions. Additionally, due to the shielding properties of the arresting and containment device, semi-destructive means such as localized EMPs could be used to damage the encapsulated unmanned vehicle electronics.
US10239636B2	Method for manufacturing a panel made of composite material incorporating a lightning protection means, and panel made of composite material manufactured by way of said method A method for manufacturing a panel made of composite material incorporating a lightning protection arrangement which comprises strips with a conductive layer. The method comprises a step of laying the strips in an automated manner, the strips having a width of less than 20 mm and being distributed in a first set of mutually parallel strips that are laid in a first laying direction and a second set of mutually parallel strips that are laid in a second laying direction that intersects the first laying direction. A panel made of composite material manufactured by way of this method is also disclosed.
US10239635B2	Methods for balancing aircraft engines based on flight data A method for balancing an aircraft turbofan engine using a respective artificial neural network for each flight of multiple reference aircraft to predict the engine vibrations that would be produced in response to input of flight parameter and balance weight data acquired from a flight of a test aircraft of the same type. The resulting sets of predicted vibrations are then processed to identify and collect those engine vibration predictions which match or nearly match the engine vibration measurements acquired from the test aircraft during its flight test. For each matching modeled flight of the reference aircraft, the magnitude and phase angle of the mass vector for any commonly used balance weight configurations are determined and included in a list of recommended balance weight configurations. A technician can then reconfigure the balance weights attached to the engine on the test aircraft in accordance with a selected recommendation.
US10239632B2	System and method for controlling an auxiliary power unit inlet door A system and method for controlling an inlet door of an auxiliary power unit (APU) are provided. It is determined whether a condition to inhibit a start of the APU is present. If no condition to inhibit the start of the APU is present, a door-opening signal comprising instructions to cause the inlet door to be commanded to an open position in advance of a prospective command to start the APU is output. If the condition to inhibit the start of the APU is present, a door-closing signal comprising instructions to cause the inlet door to be commanded to a closed position is output.
US10239631B2	Aircraft receptacle A system and method for an aircraft receptacle. The aircraft receptacle comprises an actuator connected to a number of latches and a tension spring connected to the number of latches. The actuator is part of an actuation system. The elastic member holds the number of latches in a disengaged position after failure of the actuation system.
US10239628B2	Set of latches with identical components for nacelle doors A nacelle for an aircraft propulsion system includes a first nacelle door, a second nacelle door and a plurality of latch assemblies. Each of the nacelle doors extends along and partially about a centerline. The latch assemblies are arranged along the centerline in an array, and configured to secure the nacelle doors together. A first of the latch assemblies includes a first latch mechanism and a first pin that pivotally mounts the first latch mechanism. A second of the latch assemblies includes a second latch mechanism and a second pin that pivotally mounts the second latch mechanism. An axis of the second pin is non-parallel with an axis of the first pin. The latch assemblies may be substantially identical to one another given the arrangement of the latch assemblies with the nacelle doors.
US10239627B2	Aircraft engine unit comprising an improved front engine attachment An aircraft engine unit comprising an engine, a mast and an engine connection connecting the engine and the mast. The aircraft engine unit includes a front engine attachment of the engine connection which comprises at least one front rod connecting the primary structure of the mast and the core of the engine and which assures the take-up of vertical forces, and at least one connection connecting the primary structure of the mast and the fan casing of the engine and which assures the take-up of forces that are horizontal and perpendicular to the axis of rotation of the engine and/or a torque about the axis of rotation of the engine.
US10239624B2	Reverse air cycle machine (RACM) thermal management systems and methods An aircraft includes a thermal management system that is configured to cool portions of the aircraft. The thermal management system includes at least one reverse air cycle machine (RACM) mounted on an engine of the aircraft, and a vapor cycle system (VCS) that is configured to cool the portions of the aircraft. The VCS circulates a refrigerant therethrough. A condenser couples the RACM(s) to the VCS. The RACM(s) coupled to the condenser provides a heat sink for the VCS.
US10239620B2	Aircraft seat device having an air bag element An airplane seat device includes at least one airplane seat, and at least one console arranged, viewed in a flight direction, in front of the airplane seat, and at least one airbag element which is configured to protect in a crash event a passenger sitting in the airplane seat from crashing onto the console. At least one airbag element features, in a fully deployed state, at least in a head-impact zone, a thickness which is smaller than a thickness in at least one shoulder-impact zone.
US10239616B2	Apparatus and method for providing package release to unmanned aerial system Systems, apparatuses, and methods are provided herein for providing package release for an unmanned aerial system. An apparatus for releasing packages for retrieval by an unmanned aerial system comprises a plurality of arms configured to surround a plurality of packages stacked vertically in an extended position, a plurality of powered hinges at a base of each of the plurality of arms, and a control circuit coupled to the plurality of powered hinges. The control circuit being configured to: determine a height for a first lowered position for the plurality of arms at which the plurality of arms do not obstruct an unmanned aerial vehicle from coupling with a coupling structure on a first package of the plurality of packages positioned at a top of the plurality of packages, and cause the plurality of powered hinges to pivot the plurality of arms from the extended position to the first lowered position.
US10239615B2	Personal flight vehicle A personal flight vehicle including a platform base assembly that provides a surface upon which the feet of an otherwise free-standing person are positionable, and including a plurality of axial flow propulsion systems positioned about a periphery of the platform base assembly. The propulsion systems generate a thrust flow in a direction substantially perpendicular to the surface of the platform base assembly, where the thrust flow is unobstructed by the platform base assembly. The thrust flow has a sufficient intensity to provide vertical takeoff and landing, flight, hovering and locomotion maneuvers. The vehicle allows the pilot to control the spatial orientation of the platform base assembly by the movement, preferably direct, of at least part of his or her body, and the spatial movement of the vehicle is thus controlled.
US10239612B1	Automated commissioning and floorplan configuration An automated commissioning and floorplan configuration (CAFC) device can include a CAFC system having a transceiver and a CAFC engine, where the transceiver communicates with at least one device disposed in a volume of space, where the CAFC engine, based on communication between the transceiver and the at least one device, commissions the at least one device.
US10239609B2	Pitch link with track adjustment indicators A system and method for measuring, or otherwise determining pitch length adjustments to a pitch link coupled to a rotor blade in a rotorcraft includes vertical track adjustment indicators machined onto an exterior of the tube of the pitch link and a vertical reference indicator machined onto an exterior of the upper or the lower rod of the pitch link. A metric of a pitch length adjustment can be determined by tracking or counting how many track adjustment indicators pass the reference indicator while the tube of the pitch link is being turned in either direction for increasing or decreasing the pitch length. The track adjustment indicators can be relied upon to track one or a series of adjustments for tracking a rotor blade installed in a rotor assembly.
US10239607B2	Retractable landing gear A method for actuating a landing gear arrangement may include supplying a first pressure to an actuator, applying, by the actuator, a moment on a latch to rotate the latch in a first rotational direction, disengaging a first roller pin, engaging a stopper on a link, rotating the link in the first rotational direction about a pivot, the link coupled between a trailing arm and a shock strut, rotating the shock strut about a second end of the shock strut, rotating the trailing arm about a first end, and engaging a second roller pin.
US10239603B2	Upper attachment for trimmable horizontal stabiliser actuator An upper attachment system for a trimmable horizontal stabilizer actuator (THSA) comprises: a housing, holding a yoke and a ballscrew; a nut coupled to the housing and cooperating with the ballscrew such that rotation of the ballscrew relative to the nut results in linear motion of the ballscrew; a recess formed between the yoke and the ballscrew and arranged to receive, in use, an upper part of a tie bar of the secondary load path of the actuator; and a biasing mechanism arranged such that, in use, when no axial load is applied to the tie bar, the yoke and the ballscrew are held by balanced forces from the biasing mechanism in a position within the recess.
US10239602B2	Multi-spar torsion box structure Disclosed is a multi-spar torsion box structure comprising a plurality of spars of composite material arranged to form a multi-cell structure with two or more cells extending longitudinally along the torsion box, and upper and lower skin covers formed of composite material and joined to upper and lower surfaces of the multi-cell structure, respectively. The structure further comprises at least one belt-like reinforcing element extending around the outer perimeter of the torsion box, and fixed to the upper and lower surfaces of the multi-cell structure, and transversely arranged with respect to the longitudinal direction of the torsion box. The belt-like reinforcing element is made of a metallic or a composite material. The disclosed torsion box can advantageously be used in the manufacture of aircraft lifting surfaces, such as horizontal tailplanes (HTP) or wings.
US10239601B2	Method and device for fireproofing a part in composite material A device for fireproofing a section of a structural part made of composite material. The device includes a skin having an outer surface configured to face the flame and an inner surface. The skin is made of composite material that includes fibrous reinforcement in a polymer matrix. The skin includes a fastener to fasten the part to the structure. The device includes a layer of needled mineral felt placed between the inner surface of the skin and a surface of the structural part.
US10239599B1	Stern drive arrangements having idle relief exhaust gas bypass A stern drive arrangement is for propelling a marine vessel in water. A diverter valve is movable into and between an open position in which the exhaust gas is allowed to flow through the above-water outlet via the secondary exhaust conduit and a closed position in which the exhaust gas is at least partially prevented from flowing through an above-water outlet via a secondary exhaust conduit. Via a bypass conduit, the exhaust gas in the secondary exhaust conduit can bypass the diverter valve and discharge to atmosphere when the diverter valve is in the closed position.
US10239594B2	Nesting Fenders An arrangement of fenders nested together for compact storage, the fenders including two or more cylindrical bodies having a cavity accessed through the fender top, the fenders being similar shape but graduated in size such that the cavity of a larger fender tensionally receives the next smaller sized fender, the outer diameter of the smaller fender equal to the inner diameter of the larger fender cavity. A fender has a rigid inner core surrounded by a compressible shell made of foam or similar material. The inner core has attachment points for a rope or line. The smallest nesting fender in the set has a cavity diameter sized to fit a commercially-available, off-the-shelf fender. The fenders may be separated and deployed at individual locations on a vessel, or kept together and deployed as a single fender capable of absorbing a greater impact than any of the fenders individually would absorb.
US10239585B2	Rope tender for watercraft A rope tender for a recreational watercraft is removably attached to the top of an outboard motor or a transom of the watercraft. The rope tender has a partial labyrinth slot which captively receive one or more anchor or mooring ropes to prevent entanglement of the ropes with the motor or propellers associated therewith. The rope tender may be conveniently removed and stowed when the watercraft is configured in an operational condition.
US10239580B2	Bicycle frame with front derailleur mounting structure A bicycle frame includes a first frame member and a second frame member configured to be pivotally connected to the first frame member about a pivot axis. The first frame member includes a threaded hole, through which a fixing bolt for fixing a mounting member of a bicycle front derailleur to the first frame member passes, and an abutting portion configured to restrict rotation of a mounting member of a bicycle front derailleur around the fixing bolt by abutting the mounting member. The threaded hole is located on a front side of the pivot axis.
US10239578B2	Electric propulsion system for a vehicle, particularly a battery-powered e-bike, S-Pedelac, e-bike with control in different modes The invention relates to a drive system for a vehicle, having a drive or electromotor, a crankshaft and a transmission, in particular a hub transmission. It is provided according to the invention that the transmission (10) is arranged in the central region of the vehicle, in particular the region of the crankshaft (1) and in particular is integrated and the crankshaft rotational speed is transmitted.
US10239577B2	Transmission for a human powered vehicle (HPV) and such vehicle The transmission is for transmitting a reciprocating pedal movement into a rotational movement and comprises a pair of pedals suspended for reciprocating movement, two rotating cam members (29) rotating around respective cam axes (33), each rotating cam member (29) having a peripheral cam surface (31), the rotating cam members (29) being coupled to a rotating member (35) through a respective one-way clutch. Flexible tension members (63) are connecting either pedal to a respective one of the rotating cam members (29), which are eccentric to provide for a gearing ratio between angular movement of the rotating cam member (29) and translational movement of the respective pedal to vary, such that the gearing ratio has a minimum value when the pedal is in an intermediate position between its extended position and its retracted position, and major values when the pedal is in its retracted or extended position.
US10239575B2	Inverted two-wheeled vehicle An inverted two-wheeled vehicle includes: an inverted two-wheeled vehicle body; a pair of step plates, a rider putting both feet on the pair of step plates; a parallel link mechanism that links the pair of step plates so that the pair of step plates are inclined to the right or the left in unison; a handle that is supported by the inverted two-wheeled vehicle body; and a controller that controls a turning movement of the inverted two-wheeled vehicle according to an inclination of the pair of step plates in the horizontal direction. The handle is supported by the inverted two-wheeled vehicle body so that the handle does not work with the pair of step plates when the step plates are inclined to the right or the left.
US10239571B2	Off-highway recreational vehicle A vehicle configuration wherein the center of mass of the vehicle is approximately superimposed upon the passenger and driver centers of mass when seated within the vehicle. An occupant's center of mass can be approximated using a standard center of mass position approximation, or a combination of any number of standard center of mass position approximations. The vehicle's center of mass can be approximately superimposed upon the occupant's center of mass in at least the longitudinal and vertical directions.
US10239569B2	Track assembly for farm implement A mobile farm implement includes a track assembly with a plurality of arms that are pivotally coupled to support idler wheels and bogie wheels such that the track assembly is able to better conform to the terrain when the implement is towed behind a tractor or otherwise moved.
US10239568B2	Fuel efficiency of road vehicles An aerodynamic unit is configured for attachment onto a roof of a road vehicle, so that air passes over the unit during forward movement of the road vehicle. The unit has a first end for positioning distal to a rear end of a vehicle roof, and a second end for positioning proximal a rear end of a vehicle roof. The unit includes an inclined guide portion which decreases in height in a direction towards the trailing end of the unit. The unit also includes a flow director at or near the leading end of the aerodynamic unit, for directing air flow to the guide portion. The flow director is configured to have a height increasing in a direction from the leading end towards the trailing end. The unit may include vortex generators protruding from the guide portion. A fin may extend along each side of the unit in a direction between the trailing end and the leading end.
US10239567B1	Extendable truck bed The extendable truck bed comprises and extension bed floor and extensible side panels that allow the cargo bed of a pickup truck to be expanded so as to provide an increased cargo capacity. The extendable truck bed moves from a ‘nominal bed length’ position to an ‘extended bed length’ position under control of one or more operator controls that may be located in the cab of the truck. In the ‘nominal bed length’ position the extension bed floor is located beneath the truck bed floor and the extensible panels are located in a left side panel pocket and a right side panel pocket in the side walls of the truck bed. A left side motor and right side motor drive a left side flexible linkage and a right side flexible linkage to move the extension bed floor and extensible side panels to the ‘extended bed length’ position.
US10239566B2	Composite floor for a dry truck body A vehicle is disclosed having a composite cargo body. A floor of the cargo body is constructed of a first composite material. A roof, a right sidewall, a left sidewall, and a nose of the cargo body are constructed of a second composite material different from the first composite material. Various components of the composite cargo body are bonded together with an adhesive. Mechanical fasteners also may be used to join other components of composite cargo body.
US10239561B2	Side collision load transmission structure A side collision load transmission structure including a floor tunnel, a vehicle compartment side wall, a vehicle seat, side frames, a first transmission member that couples together lower end portions of the pair of side frames along the vehicle width direction, a load receiving member, and a second transmission member that couples together a portion further to a seatback up-down direction upper side than a join portion with the first transmission member on the side frame, out of the pair of side frames, on the vehicle compartment side wall side and a portion of the first transmission member that is further to a vehicle width direction outside than the length direction center of the first transmission member so as to be coupled at an incline as viewed from the front of the vehicle.
US10239558B2	Vehicle lower section structure A vehicle lower section structure including: a left and right pair of vehicle body frame members; a lower extension section joined to each of the left and right pair of vehicle body frame members, the lower extension section including: a front lower extension section extending toward a vehicle lower side, and a rear lower extension section disposed at a vehicle rear side of the front lower extension section and extending toward the vehicle lower side; and a front-rear direction extension section that bridges the vehicle front-rear direction between the front lower extension section and the rear lower extension section, the front-rear direction extension section provided with a lower arm support section that a lower arm is attached to pivotably substantially a vehicle vertical direction, and the front-rear direction extension section being joined to the rear lower extension section at the vehicle rear side of the lower arm support section.
US10239554B2	Electric power steering apparatus An electric power steering apparatus includes a steering angle control section that calculates a steering angle control current command value for the steering angle control, calculates the current command value using at least the steering angle control current command value; the steering angle control section includes a position control section that calculates a basic steering angular velocity command value, a steering intervention compensating section that obtains a compensatory steering angular velocity command value, and a steering angular velocity control section that calculates the steering angle control current command value by the basic steering angular velocity command value, the compensatory steering angular velocity command value and an actual steering angular velocity; the steering intervention compensating section includes a compensation gain section that multiplies the steering torque by a steering intervention compensation gain, and obtains the compensatory steering angular velocity command value by the steering torque through the compensation gain section.
US10239553B2	Power converter A power converter for a three-phase electric rotary machine including first and second winding sets includes: first and second inverters corresponding to the first and second winding sets, respectively; and a control unit including a command calculation unit that calculates first and second voltage command values related to voltages to be applied to the first and second winding sets, and an excess correction unit that corrects first and second voltage command corresponding values corresponding to the first and second voltage command values. When one of the first and second voltage command corresponding values exceeds a limitation value which is set in accordance with a voltage capable of being outputted, the excess correction unit performs an excess correction process for correcting the other of the first and second voltage command corresponding values in accordance with an excess amount over the limitation value.
US10239551B2	Steering wheel device A steering wheel device that can absorb an applied impact load. A steering wheel device includes a lower cover that covers a steering column side of the steering wheel. The lower cover includes: a bottom member facing the steering column; an open portion which at a center of the bottom member and through which a steering shaft passes; slit portions formed on both sides, the slit portions being bent and curved in predetermined shapes; buffer portions formed in the bottom member and outlined by the slit portions, the buffer portions having a free end formed on a vehicle front side and a stationary end formed on a vehicle rear side; and bridge members that can be broken and bridge each of slit portions on the free end side of each of the buffer portions.
US10239549B1	Tool holding device for a wheelbarrow A tool holding device for a wheelbarrow comprises an oblong handle channel with a longitudinal trough in which a substantial length of the tool handle is seated within multiple locking collars. Each of the locking collars comprise a u-shaped collar trough subtended by a deformable collar strip. When the tool handle is inserted into the channel trough, the collar strips wrap around the handle and cradle it tightly within the trough. The handle channel is connected through a channel flange to one of the sides or the back of the wheelbarrow tub either integrally or by attachment means in the channel flange.
US10239548B2	Multiple bag hanging cart A multiple bag hanging cart is described. Embodiments of the multiple bag hanging cart can include a longitudinal divider having a plurality of dual prong hooks and a plurality of single prong hooks spaced along right and left sides of the cart. The dual prong hooks of the longitudinal divider can be configured to be aligned with respective single prong hooks located on either side of the cart. In use, one or more bags can be hung within a basket of the cart via the dual prong hooks and the single prong hooks to allow for easy insertion of items into the bags.
US10239547B1	Pick cart A pick cart includes a first end, an opposing second end, a first side and an opposing second side, a plurality of shelves each defined by the first side, the second side, the first side and the second side and a plurality of wheels attached to a bottom of a lowermost shelf of the plurality of shelves. The wheels are configured to make the pick cart mobile. A first extrusion has a length and is mounted to the first side or the second side of each of the plurality of shelves. The first extrusion includes a channel that runs along an entirety of the length of the first extrusion. At least one movable divider is configured to divide each of the plurality of shelves into compartments. Each movable divider comprises at least one slider that is configured to mate with the channel in the first extrusion.
US10239546B1	Folding utility cart A folding utility cart incorporates a plurality of wheels attached to a lower frame, a handle frame, a pail frame, and a plurality of hinges positioned to permit the cart to fold into a space-saving configuration. The cart has a plurality of storage compartments, trays, and clips, each capable of retaining commonly associated cleaning supplies therein.
US10239545B2	Transporting apparatus A transporting apparatus including a top portion pivotally coupled to a middle portion via a latching assembly, the latching assembly including a biasing element and a latching element, the biasing element biasing latching element in a closed position which releasably secures the top portion to the middle portion in an extended position.
US10239544B1	Guided delivery vehicle A guided delivery vehicle having one or more item support regions atop a carrier body; one or more drive wheels attached or coupled to one or more powered servo motors; a receiver for receiving one or more transmitted signals; at least one junction detection sensor, wherein the at least one junction detection sensor is capable of detecting a junction identifier associated with a determined position along a guide track; and a controller that receives and processes input from at least the receiver and the at least one junction detection sensor, and, in response to a received and processed input, executes an initial command step and sequentially executes subsequent command steps upon detection of a subsequent junction identifier.
US10239542B2	Railroad car and door mechanism therefor A hopper car discharge outflow is controlled by closure members, at least one of which is movable. The doors are hingeless, being mounted on four bar linkages, such that the distal edge of the doors sweeps predominantly horizontally while the proximal edge of the door moves predominantly upwardly. The doors move through noncircular arcs, such that the size of the vertically projected door opening is abnormally large compared to the clearance heights of the door. The doors are driven by a longitudinal shaft that is mounted within the center sill. It drives a set of single input, double output bell cranks that drive adjacent pairs of doors, and that employs an over-center toggle to hold the doors in the closed position when the car is laded. The actuators may be mounted in shelters midway along the car, and may be offset from the centersill. The actuators may be mounted predominantly vertically such that gravity may obviate the need for a secondary lock. The doors of a transverse car need not all be of the same size. The over center may include a manual release having a fulcrum with a progressive decrease in mechanical advantage.
US10239535B2	Engine control device for hybrid construction machinery The present disclosure relates to an engine control device for hybrid construction machinery, and more particularly, and an object of the present disclosure is to, in a hybrid excavator, in which a swing apparatus is electrically driven by being separated from a hydraulic power train system in the related art, satisfy a minimum rotational speed of an engine auxiliary motor which is necessary to satisfy a target charging amount required for an energy storage device, and improve fuel efficiency by removing unnecessary energy loss at low loads by controlling a rotational speed of an engine to be lower than a rotational speed of an engine determined based on a dial input and a mode input in the related art, in a case where a target power generation amount of the engine auxiliary motor is small in a low-load work situation.
US10239527B2	Driving ratings for leading or following vehicle selection Driving rating information for other vehicles in an external environment of a vehicle can be provided. The external environment of the vehicle can be sensed to detect the other vehicles. Driving rating information for the other vehicles can be received, such as directly from the other vehicles or from a remote driving ratings source. The driving rating information for the other vehicles can be presented within the vehicle. Based on such driving rating information, a vehicle occupant can decide whether or not to lead or follow a particular vehicle in the external environment. If a selection of one of the identified one or more vehicles is received from a vehicle occupant, the vehicle can be caused to implement one or more driving maneuvers relative to the selected vehicle.
US10239526B2	Adaptive cruise control system Systems and processes are provided for adaptive cruise control. The process includes receiving information about a distance between vehicle and a traffic signal, receiving information about a state of the traffic signal, and determining whether to adjust the speed of the vehicle based upon the distance between the vehicle and the traffic signal and the state of the traffic signal.
US10239525B2	Driving support information generation device, driving support information generation method, driving support device, and driving support method It is an object of the present invention to provide a driving support information generation device, a driving support information generation method, a driving support device, and a driving support method which make it possible to present effective caution information to drivers. The driving support information generation device of the present invention includes a processor to execute a program; and a memory to store the program which, when executed by the processor, performs processes of collecting vehicle information including traveling locus information indicating a traveling locus of at least one vehicle which travels a predetermined road section and generating cautionary information which is information to require a driver of the at least one vehicle to exercise caution when the at least one vehicle travels the section, on the basis of the collected vehicle information. The cautionary information is generated on the basis of variation in traveling of the vehicle.
US10239521B1	Multi-network-based path generation for vehicle parking Systems and methods of deep neural network based parking assistance is provided. A system can receive data sensed by one or more sensors mounted on a vehicle located at a parking zone. The system generates, from a first neural network, a digital map based on the data sensed by the one or more sensors. The system generates, from a second neural network, a first path based on the three-dimensional dynamic map. The system receives vehicle dynamics information from a second one or more sensors located on the vehicle. The system generates, with a third neural network, a second path to park the vehicle based on the first path, vehicle dynamics information and at least one historical path stored in vehicle memory. The system provides commands to control the vehicle to follow the second path to park the vehicle in the parking zone.
US10239519B2	Vehicle state estimation device Provided is a vehicle state estimation device (10) having a calculation unit (28) that calculates state quantities of at least a sprung of a vehicle based on wheel speeds of front left and right wheels and rear left and right wheels detected by detection devices. The calculation unit (28) calculates in-phase and reverse phase components of wheel speeds of left and right wheels for the front and rear wheels and calculates a pitch angular speed and a yaw angular speed of the sprung based on the in-phase and reverse phase components of the wheel speeds, respectively. The calculation unit (28) calculates in-phase and reverse phase components of vertical strokes of left and right suspensions for the front and rear wheels and calculates a vertical speed and a roll angular speed of the sprung based on the in-phase and reverse phase components of vertical strokes of the suspensions, respectively.
US10239516B2	Front end motor-generator system and hybrid electric vehicle operating method A system and method are provided for hybrid electric internal combustion engine applications in which a motor-generator, a narrow switchable coupling and a torque transfer unit therebetween are arranged and positioned in the constrained environment at the front of an engine in applications such as commercial vehicles, off-road vehicles and stationary engine installations. The motor-generator is preferably positioned laterally offset from the switchable coupling, which is co-axially-arranged with the front end of the engine crankshaft. The switchable coupling is an integrated unit in which a crankshaft vibration damper, an engine accessory drive pulley and a disengageable clutch overlap such that the axial depth of the clutch-pulley-damper unit is nearly the same as a conventional belt drive pulley and engine damper. The front end motor-generator system includes an electrical energy store that receives electrical energy generated by the motor-generator when the coupling is engaged. When the coupling is disengaged, the motor-generator may drive the pulley portion of the clutch-pulley-damper to drive the engine accessories using energy returned from the energy store, independent of the engine crankshaft.
US10239512B2	Engagement structure of push-rod guide and push-rod guide cover of brake chamber for vehicle The present disclosure relates to an engagement structure of a push rod guide and a push rod guide cover of a brake chamber for a vehicle, in which a pair of semi-circular, hingedly connected, half members in a shape of a plate are assembled at a side surface of an axial direction of the push rod into a shape of a disk, a push rod opening is formed at the center of the disk to guide a movement of the push rod, a protrusion projecting upwards is provided at a central part of the push rod guide, forming a step in a radial direction of the push rod guide, and a receiving groove corresponding to the step is formed on an inner circumferential surface of the push rod guide cover and is connected to the step.
US10239504B2	System and method pertaining to braking of a vehicle combination which comprises a tractor vehicle with a towed vehicle A method pertaining to braking of a vehicle combination (100) which combination comprises a tractor vehicle (110) with a towed vehicle (112), where both are configured to be braked. The tractor vehicle (110) is provided with a first control unit (200) having a function for regulation of coupling force between the tractor vehicle (110) and the towed vehicle (112). Regulation of coupling force includes adaptation data and the towed vehicle bears an ID specification. The method includes the steps of: transferring the ID specification from the towed vehicle (112) to the tractor vehicle (110); during a braking process, registering adaptation data associated with the braking process together with the ID specification. Also a computer program product includes program code (P) for a computer (200; 205) for implementing the method. Also a system pertaining to braking of a vehicle combination (100) and to a vehicle combination (100) is equipped with the system.
US10239501B2	Underside washing device for an automobile A device to wash an underside of an automobile comprises a handle comprising a first end and a second end, wherein a fluid flow through the first end of the handle is regulated via a valve member, wherein the handle comprises a canister to store and dispense one or more detergents during the wash. A pipe section fixedly attached to and extending obliquely from the second end of the handle to couple with a horizontal member via an elbow section and the horizontal member comprising a spraying head positioned at a distal end of the horizontal member, wherein the spraying head comprises a plurality of nozzles to spray the fluid in the underside of the automobile during the wash. A method of washing an underside of an automobile using the device is also disclosed.
US10239498B2	Connector between a wiper blade and a wiper arm driving a wiping system A connector for a wiper blade, the connector is configured to cooperate pivotably, by a transverse hinge pin, with an adapter designed to allow an articulation link between the blade and a driving arm, the connector includes a body provided with two opposite side flanges, defining a housing designed to receive the adapter, and a pin between the flanges for the articulation link of the blade to the arm, the flanges include, at each of the ends of the hinge pin, a shoulder configured to allow axial guiding of the articulation link between the blade and the arm, the side flanges is configured to allow lateral flexion of the adapter bearing against the shoulder.
US10239490B2	System and method for communicating with a vehicle A communication system includes a control module, a primary wireless communication node, and a plurality of secondary wireless communication nodes. The primary wireless communication node is in communication with the control module. The primary wireless communication node is in communication with each of the plurality of secondary wireless communication nodes through a common communication line.
US10239485B2	Belt buckle device for a seat belt A belt buckle device (1) for a seat belt including a belt buckle, a drive device (2) coupled or coupleable to the belt buckle, threaded sleeve (5) coupled or coupleable to the belt buckle, a guide part (12) attachable fixed with respect to the vehicle for guiding the threaded sleeve (5) and for supporting the threaded spindle (10), wherein a support plate (9) is provided on the threaded spindle (10) in the axial direction of the threaded spindle (10), which support plate (9) is not displaceable by a tensile force exerted by the belt buckle, via which support plate (9) the threaded spindle (10) is supported in the axial direction on a first thrust support (6) of the guide part (12) to take up tensile forces exerted by the belt buckle.
US10239484B2	Active hood apparatus for vehicle An active hood apparatus for a vehicle includes a hood configured to cover an engine compartment of vehicle, and at least one hinge device configured to rotatably connect a rear end portion of the hood to a vehicle body. The hinge device includes a fixing bracket fixed to the vehicle body. A rotation bracket is provided such that a rear end thereof is rotatably connected to a rear end portion of the fixing bracket. A hood bracket is fixed to an inner surface of the hood and fixed to the rotation bracket by a first breaking pin. A connecting link provided such that opposite ends thereof are rotatably connected to a rear end portion of the hood bracket and a middle portion of the rotation bracket respectively. An actuator is configured to push up the connecting link in the event that a collision occurs.
US10239479B2	Vehicle safety system for controlling a safety feature A safety system for a vehicle includes an imaging sensor configured to be disposed at a vehicle so as to have an exterior field of view external of the equipped vehicle. An image processor is operable to process image data captured by the imaging sensor to detect a vehicle exterior the equipped vehicle and to determine if a collision between the detected vehicle and the equipped vehicle is pending. Responsive to such determination of the pending collision, a safety feature of the vehicle is triggered before impact occurs. Responsive at least in part to processing by the image processor of captured image data to determine if a collision between the detected vehicle and the equipped vehicle is pending, the safety system takes into account if a determined impact speed of the detected vehicle relative to the equipped vehicle is above a threshold level.
US10239477B1	Battery charge management for geosynchronous spacecraft A spacecraft, configured to be operated in a geosynchronous orbit includes a power subsystem, including a battery, and a battery charge controller. The spacecraft is configured to have a power demand, during an eclipse season of the geosynchronous orbit, of ‘P’ kilowatts and the battery is sized to have a nominal capacity, measured in kilowatt-hours, smaller than 1.2*P/0.85. In some implementations, the battery has a rated charge voltage corresponding to the nominal capacity and the battery charge controller is configured to execute a battery charge management strategy that charges the battery to an above-rated charge voltage during selected portions of the eclipse season.
US10239475B2	Wind noise throb reduction system and method A wind noise throb reduction system includes a controller configured to reduce wind noise throb, an active noise cancellation subsystem responsive to the controller and a dynamic airflow control subsystem responsive to the controller. A related method of reducing wind noise throb in a passenger compartment of a motor vehicle is also provided.
US10239474B1	Corrugated tube and wire harness A corrugated tube of the present invention has a rigid portion, a bellows portion, and a gradually varying portion. The rigid portion is formed in an end portion of the tube, and has a first half-circumference portion having a recess/projection-repetitive structure in which grooves and projection strips are arranged alternately in the tube longitudinal direction and a second half-circumference portion having a straight structure with no grooves or projection strips. The bellows portion is formed in a center portion of the tube and has the first and the second half-circumference portions both of which have a recess/projection-repetitive structure. The gradually varying portion is formed between the rigid portion and the bellows portion, and has the first half-circumference portion having the recess/projection-repetitive structure and the second half-circumference portion having the gradually varying structure in which the height of the projection strip decreases gradually from the bellows portion to the rigid portion.
US10239473B2	Wiring guide of vehicle door A wiring guide of a vehicle door includes: an outside guide slidably disposed on one of a vehicle body and a door of a vehicle, and having an inner portion which has a hollow and circular arc shape; and an inside guide slidably disposed on the other side of the vehicle body and the vehicle door, having an inner portion which has a hollow and circular arc shape, slidably disposed in the inner portion of the outside guide, and having a wiring penetrating therein. The outside guide and the inside guide expand and shrink in a circular arc shape upon opening and closing of the door.
US10239471B2	Iridescent vehicular trim assemblies and multi-shot injection molding methods for making the same A method of making an iridescent, vehicular trim assembly is provided that includes: molding a polymeric base comprising an exterior surface; and over-molding an element over at least a portion of the exterior surface. The element comprises a polymeric, translucent material and an exterior surface with an integral diffraction grating having a thickness from 250 to 1000 nm and a period from 50 nanometers to 5 microns. Further, the molding can be conducted such that the polymeric base is molded with a tint. The method can also include forming a plated region over the exterior surface of the base. In addition, the method can also include cleaning the plated region with a plasma-etching process before the over-molding.
US10239470B2	Vehicle with an integrated sawhorse An apparatus for a vehicle including a vehicle bed having a wall with a recess formed therein. The apparatus comprises a sawhorse adapted for positioning in the recess of the vehicle bed in a stowed position and removed for use apart from the vehicle. A vehicle with an integrated sawhorse may thus be provided. Related methods are also provided.
US10239467B2	Holder for mobile communications device A method is provided for mounting a mobile communications device (404) on a substrate. In accordance with the method, a holder (401) is provided which includes (a) a back wall (407) having attaching means thereon for releasably attaching the holder to a substrate, and (b) a front wall (405) opposing said back wall. The holder is releasably mounted on an interior surface of a vehicle. The front wall has a sloped profile which extends a distance d1 from said bottom wall along said first edge as measured along a first axis perpendicular to said bottom wall and parallel to said front wall, and which extends a distance d2 from said bottom wall along said second edge as measured along a second axis perpendicular to said bottom wall and parallel to said front wall, and wherein d1
US10239466B2	Avionics display fastener assembly A fastener assembly for aircraft cockpit electronics can include a spring locking quarter turn fastener, where a head of the fastener can be positioned on a non-display side of the assembly, and a thread of the fastener can extend to a display side of the assembly. The fastener assembly can additionally include a spring assembly and mounting hardware.
US10239463B2	Lift storage device for a vehicle including lift assist A storage device for a vehicle is disclosed. In one embodiment, the storage device has an exterior housing, an interior container, and a scissor lift mechanism. The scissor lift mechanism is located within the exterior housing and is operatively connected to the interior container. The scissor lift mechanism has a raised position and a lowered position. The interior container is within the exterior housing when the scissor lift mechanism is in the lowered position. The interior container is at least partially located outside the exterior housing when the scissor lift mechanism is in the raised position. The scissor lift mechanism includes crossed bars that pivot about a bolt or pin in scissor-like fashion to raise or lower the interior container. An actuator pivots the cross bars to the raised position and is oriented and connected to the crossed bars to have an upward vertical force component throughout the raising operation.
US10239462B2	Cargo carrier and quick hitch mount A cargo carrier has a frame, a wheel assembly coupled to the frame, and a quick release assembly. The quick release assembly allows the user to quickly raise and lower the wheel assembly with respect to the frame, or to turn an adjusting screw to more finely raise and lower the wheel assembly. In addition, a vehicle hitch mount has an outer tube and an inner tube slidably received in the outer tube. The inner tube has a retracted position in which the inner tube is retracted with respect to the outer tube, and an extended position in which the inner tube is extended with respect to the outer tube. A locking pin can be operated by the user at one side of the cargo carrier to removably lock the hitch mount to the vehicle hitch located at an opposite side of the cargo carrier.
US10239457B2	Vehicular vision system A vision system for a vehicle includes a forward-viewing camera located behind and viewing through a vehicle windshield, a rear camera located at a rear of the vehicle, and a common image processor operable for processing captured image data. A video display screen is located within the interior cabin of the vehicle viewable by a driver of the vehicle. The common image processor utilizes object detection software at least during processing of first image data captured by the forward-viewing camera to detect at least one vehicle present exterior the equipped vehicle. Responsive to the vehicle being shifted into a reverse gear and while the driver is executing a reversing maneuver, video images derived from image data captured by at least the rear camera are displayed on the video display screen.
US10239448B1	Unattended occupant alert system An unattended occupant alert system includes a car seat that may be positioned in a vehicle. A child is selectively seated in the car seat and the car seat has a pair of shoulder straps. An electronic device is included and the electronic device is carried by a caregiver. An alarm unit is coupled between the shoulder straps to selectively and removably attach the shoulder straps together. In this way the alarm unit retains the child in the car seat and the alarm unit is turned on when the shoulder straps are attached together. The alarm unit is in thermal communication with an interior of the vehicle to detect a temperature in the vehicle. Additionally, the alarm unit is in electrical communication with the electronic device. The electronic device emits an alert when the alarm unit is turned on and the alarm unit detects a temperature that exceeds a trigger temperature. In this way the alarm unit alerts the caregiver to a potential environmental danger for the child.
US10239446B2	Vehicle sensing system using daisy chain of sensors A sensing system for a vehicle includes a plurality of sensors disposed at the vehicle. The plurality of sensors includes individual sensors connected to a vehicle network using a daisy chain topology. A control determines an address of the sensors and calibrates the sensors. The control, responsive to determination that an individual sensor is not the last sensor of a daisy chain of sensors, adjusts the internal electrical configuration to provide an open connection for another sensor. The control, responsive to determination that an individual sensor is the last sensor of the daisy chain of sensors, adjusts the internal electrical configuration to provide a termination configuration. The control, responsive to the outputs of the sensors, determines the presence of one or more objects exterior the vehicle and within the field of sensing of at least one of the sensors.
US10239440B2	Illumination apparatus for vehicle An illumination apparatus for a vehicle includes a projector configured to project an image of visible light; an obstacle detection apparatus configured to detect an obstacle; and a processing apparatus configured to predict a travel area of the vehicle after a predetermined time or a predetermined distance of travel, project a first image with the projector in the predicted travel area upon no obstacle in the predicted travel area being detected by the obstacle detection apparatus, and project a second image, which is different from the first image, with the projector in the predicted travel area upon the obstacle in the predicted travel area being detected by the obstacle detection apparatus.
US10239439B2	Tension monitoring and signaling system An automatic tension sensing and control system for cargo restraints comprises a load binder, a tension sensor, an actuator coupled to the load binder, and a control module. The control module receives signals from the sensor and can command the actuator to tighten or slacken the load binder. The system can also include an annunciator and an information storage and retrieval system.
US10239438B2	Device for lashing of containers The present invention relates to a device for the lashing of containers, which is to be attached between two fastening points, which are secured to one another, with a first clamping device, which can be connected to one of the fastening points and contains a spindle, which extends in the longitudinal direction of the first clamping device and has a spindle/threaded section, a second clamping device, which can be connected to the other of the fastening points, a spindle nut, which has a spindle nut/threaded section, which engages with the spindle/threaded section of the first clamping device, a locking means allocated to the spindle nut. The locking means enables reciprocal rotation of the two clamping devices in at least one direction of rotation corresponding to the tightening of the device, and that it counters the rotation in the opposite direction, and the locking means has at least one pre-tensioning element.
US10239437B2	Load binder systems A binder includes a right angle drive including a driving gear interfacing with a driven gear. A receptacle arranged substantially at a center of a diameter of the driving gear can receive a bit of a power driver. The bit of the power driver removeably received by the receptacle arranged at the center of the driving gear can rotate a threaded gear tube relative to the first and second threaded rods to linearly displace the first and second threaded rods of the binder to tension a tensionable load bearing member and lock the binder.
US10239432B2	Acoustic output through headrest wings The technology described in this document can be embodied in a headrest of a seat, the headrest including an enclosure for housing one or more acoustic transducers, and an adjustable headrest wing disposed in front of the enclosure. The headrest wing is coupled to the enclosure by a pivot, and configured to be adjusted to one of multiple positions within an angle range around the pivot. The headrest wing is also configured to support the head of a seat-occupant. The headrest further includes a connector disposed between the enclosure and a rear portion of the headrest wing. The connector is configured to provide an acoustic channel between the enclosure and the headrest wing such that audio signals from the one or more acoustic transducers are radiated outward through the headrest wing.
US10239429B2	Vehicle seat A seating posture is stabilized for the shoulders of a passenger seated on a vehicle seat. A vehicle seat is provided with a seat back configured to support the seated person from the rear. A shoulder support portion of the seat back configured to support a corresponding one of the shoulders of the seated passenger includes an air cell configured to expand when air is supplied. When the air cell expands, one end portion of the shoulder support portion on the outside in the width direction of the vehicle seat moves more forward than the other end portion of the shoulder support portion on the inside in the width direction.
US10239424B2	Vehicle seat A vehicle seat includes a seat pad configured to support an occupant and having a through-hole extending through the seat pad in a direction from an occupant sitting side toward a side opposite to the occupant sitting side; and a frame member attached to an opening end of the through-hole on the occupant sitting side, the frame member having an opening configured such that a fixation connecting portion of a child safety seat is inserted into the opening. The frame member is provided with an attaching portion attached to the seat pad. The seat pad includes an attachment pad portion provided integrally with an attachment member including an attachment portion to which the attaching portion of the frame member is attached, the attachment pad portion constituting a part of an inner wall surface of the through-hole. The attaching portion is fixed to the attachment portion with a fixing member.
US10239423B2	Tip and slide system for a vehicle seat A vehicle seat includes a seatback pivot rotationally operable relative to a slidable base, a first cam in communication with the seatback pivot to activate a track-overslide actuator of the base when the seatback pivot is in a rear-entry position and a second cam in communication with the seatback pivot. When the track-overslide actuator is activated, forward operation of the base locks the seatback pivot in the rear-entry position.
US10239422B2	Connecting element A connecting element (3) for adjusting the height of a vehicle seat (1) includes an angular element (3.1) with a first leg (3.1.1) having a seat part side receiving opening (3.1.5) and an opposite rail side end receiving opening (3.1.4), and a second leg (3.1.2) angled relative to the first leg (3.1.1) and a tooth element (3.2). The seat part receiving opening (3.1.5) is situated in a connection area of the first leg (3.1.1) and of the second leg (3.1.2). The tooth element (3.2) has a first section (3.2.1) configured as a circular arc with toothing (V2) that is connected at an end side to the second leg (3.1.2) and a second section (3.2.2) that is angled from the first section (3.2.1) in the direction of the receiving opening (3.1.5) on the side of the seat part and is connected to the first leg (3.1.1) at the end side.
US10239420B2	System and method for positioning a vehicle seat A system and method for positioning a seat arrangement in a vehicle includes moving the seat arrangement forward by a first amount when a certain criteria are met. The criteria may include at least one criterion related to occupancy of a seat directly behind the seat arrangement and at least one criterion related to a likelihood of an impact into the vehicle from behind the seat arrangement. The method may also include not moving the seat arrangement forward by the first amount when at least one of the criteria is not met.
US10239419B2	Anthropomorphic pivotable upper seatback support A vehicle seating assembly includes a lower seat and a seatback structure extending upwardly relative the lower seat, the lower seat and the seatback structure defining a seat H-point, and the seatback structure having an upper seatback support, a lower seatback support, and a split between the upper seatback support and the lower seatback support. The split is disposed between 270 and 300 mm, preferably about 285 mm, above the H-point along a line extending substantially parallel to the seatback structure. The upper seatback support pivots about a pivot between a rearward position and a forward position relative the lower seatback support. A motorized actuation assembly is disposed within the seatback structure and operably coupled to the upper seatback support, wherein the motorized actuation assembly pivots the upper seatback support about the pivot between the rearward position and the forward position.
US10239418B2	Multi-trajectory track and mover system A linear drive transport system may include a track that includes first, second, third, and fourth track surfaces that define perimeter boundaries of the track and a magnetic drive system. The first, second, third, and fourth track surfaces include first, second, third, and fourth trajectories about the track, respectively, which are each different from one another. A mover may move along the track and include first and second leading bearings that interact with the first and second track surfaces, respectively, and first and second lagging bearings that interact with the third and fourth track surfaces, respectively, and a reaction element that interacts with the magnetic drive system to generate a propulsive force. The first and second leading bearings may be coupled to the mover at a first fixed distance from one another, and the first and second lagging bearings may be coupled to the mover at a similar distance.
US10239415B2	Base side vehicle identification using vehicle controller switching frequency Techniques for wirelessly transferring energy to a vehicle are disclosed. An example method for wirelessly transferring energy to a vehicle according to the disclosure includes detecting a ripple frequency on a transmitter coil circuit, such that the ripple frequency is associated with a vehicle switch mode controller frequency of a switch mode controller in the vehicle, and providing an electrical current to a coil in the transmitter coil circuit based at least in part on the ripple frequency.
US10239413B2	Method for the contactless charging or discharging of a battery-operated object The invention relates to a method for the contactless charging or discharging of a battery-operated object (4) via a magnetically coupled coil pair, comprising a primary coil (6) of a charging/discharging station (2) and a secondary coil (8) of the object (4), wherein: in a first step, the object (4) is transferred into a reference position in relation to the charging/discharging station (2); in a second step, a reference parameter is determined in the reference position; in a third step, a lateral desired offset of the object (4) to the charging/discharging station (2) is determined, based on the reference parameter; and in a fourth step, based on the lateral desired offset, the object (4) is transferred into a charging/discharging position in relation to the charging/discharging station (2) in which position the contactless charging or discharging is carried out. The invention also relates to a computer program, a system (100), a charging/discharging station (2) and an object (4), which are designed to carry out the method.
US10239411B2	Excess-length-absorbing apparatus and coil unit Provided is an excessive length absorbing apparatus which absorbs the excess length of a primary resonant coil that is one of a pair of resonant coils which performs non-contact power supply via magnetic field resonance. A secondary hook in the excessive length absorbing apparatus hooks an excessive length portion of the primary resonant coil so as to hold the excess length portion of the primary resonant coil in a U-shape, and a holding member holds the secondary hook in a slidable manner.
US10239404B2	Method of controlling a vehicle A method of controlling a vehicle presenting a plurality of wheels, an engine and a clutch for selectively connecting the engine to a number of the wheels includesreceiving a torque control signal indicative of a demanded output torque of the engine, and observing a value of a first vehicle operation parameter being the vehicle speed or a parameter which is indicative of the vehicle speed,controlling the clutch so as to be engaged if the received torque control signal indicates that the demanded engine torque is minimal or below a first threshold value and the observed first vehicle operation parameter value is above a second threshold value, subsequently to the step of controlling the clutch so as to be engaged, performing a test disengagement of the clutch, including at least partly disengaging the clutch, observing a behavior, in response to the test disengagement, of a second vehicle operation parameter, and based at least partly on the observation of the behavior of the second vehicle operation parameter, determining whether to control the clutch so as to be re-engaged or disengaged.
US10239402B2	Hybrid vehicle with rankine cycle system, in-wheel motor and power module integrated with power train components A hybrid vehicle including one or more in-wheel motors, a power electronics supplying power to the one or more in-wheel motors, and a Rankine cycle system is described. The Rankine cycle system includes a pump driving a working fluid, a first three-way valve having an input, a first output, and a second output. The Rankine cycle system also includes, a second three-way valve having a first input, a second input, and an output, an evaporator receiving the working fluid from the output of the second three-way valve and heating the working fluid utilizing heat from an exhaust gas from an engine, an expander receiving the working fluid from the evaporator, and a radiator cooling the working fluid received from the expander.
US10239399B2	Seal structure for motor vehicle door A beltline sealing member includes a block portion that comes into contact with a glass run to assemble the beltline sealing member in a normal position in the longitudinal direction of the beltline sealing member.
US10239395B2	Waterproof top door for trailer A trailer has a container with top doors having a frame and weatherproof thermoplastic inserts. Sealing flaps are provided at edges of the top doors to make sealing contact with sidewall top rails or top edges of end walls and tailgate. The top doors have angled extensions with grooves for ball gaskets to overlap in hand-in-hand fashion to form a reliable seal where the top doors come together. The system provides a weatherproof means to enclose the container to prevent or deter entry of water.
US10239394B2	Tonneau cover access panel A tonneau cover access panel assembly connectable to a vehicle that eliminates the need for side rails to both locate and tension a tonneau cover. The assembly also reduces weight and complexity. The assembly incorporates a readily accessible rear latching system that reduces or eliminates interference with the tonneau cover during operation. The assembly also incorporates a tonneau cover tensioning system. The tension seals out environmental elements and holds the tonneau cover and locating bows in place. The assembly holds the tonneau in the closed tension state keeping the tonneau cover secured and tight until the cover is opened by an operator. The assembly is movable between a closed position and a fully open/stowable position and any intermediate positions. The assembly is also movable between at least a first open position and the deployed position for more limiting access to the cargo bed of the vehicle when desired.
US10239391B1	Sliding apparatus for sunroof of an automobile A sliding apparatus for a sunroof of an automobile including a shoe having a first channel and a second channel slidably connected to a rail, a guide block including a front channel connecting a lower channel to form a first path, and a rear channel connecting to an upper channel to form a second path, and a lever with a first pin projecting from a first side and a second side, a second pin projecting from the first side and a third pin projecting from the second side. The first pin is connected to the front channel and the second pin is connected to the rear channel on the first side, and the first pin is connected to the first channel and the third pin is connected to the second channel on a second side.
US10239389B2	Cargo transportation housing comprising a flexible fast door The present invention concerns a housing (1) for the transportation of a cargo, such as truck trailers, housings mounted on the chassis of a truck, or shipping containers. The housing of the present invention comprises: (a) walls (1R) defining a closed inner space (1i), (b) an opening (2) provided in one of the walls, and further comprises a rigid door comprising one or more rigid panels (3) which are movable to seal or unseal said opening (2); (c) a flexible fast door comprising a motorized driving mechanism (10) suitable for moving a leading edge (4L) of a flexible shutter (4), wherein the flexible shutter (4) comprises two lateral edges engaged in parallel guiding rails (7) fixed to two parallel and opposite edges of the opening (2), wherein the rigid panel (3) and/or the parallel edge of the opening (2) is provided with a groove to accommodate the guiding rails (7).
US10239388B2	Impact beam and method for producing an impact beam An impact beam and a method of producing the impact beam for a motor vehicle is disclosed. A light metal profile with an extrusion width is produced by flattening the light metal profile to a working width and cutting to length to form semi-finished products. The semi-finished products are subjected to further treatment by press-forming techniques to form the impact beam. The impact beam has a longitudinal length which extends transversely to the direction of extrusion of the light metal profile.
US10239387B2	Sun visor retention system A sun visor retention system includes a vehicle that has at least one sun visor. The at least one sun visor has a support bar and a panel that is rotatably coupled to the support bar. A retainer is removably coupled to the at least one sun visor. The retainer selectively frictionally engages the support bar. The retainer engages the panel such that the retainer retains the panel at a selected angle of rotation about the support bar.
US10239382B2	Vehicle air conditioner There is disclosed a vehicle air conditioner of a heat pump system in which there is prevented or inhibited frosting to an outdoor heat exchanger when heating in a vehicle interior is beforehand performed during plug-in, thereby realizing comfortable heating in the vehicle interior during running and also extending a running distance. The vehicle air conditioner includes a heating medium circulating circuit 23 to heat air to be supplied from an air flow passage 3 to a vehicle interior, a controller has frosting estimation means for estimating frosting to an outdoor heat exchanger 7, and when a heating mode is executed in a state where a power is supplied from an external power source to a compressor 2 or a battery which supplies the power to drive the compressor 2, the controller executes the heating by a heating medium circulating circuit 23, in a case where the frosting to the outdoor heat exchanger 7 is predicted on the basis of the estimation of the frosting estimation means.
US10239374B2	Axle unit An axle unit comprising a first suspension arm element and a second suspension arm element, wherein the first suspension arm element and the second suspension arm element can be mounted on a vehicle frame so as to be pivotable about a common pivot axis, wherein the first suspension arm element has a first joining region configured as a recess, and the second suspension arm element has a second joining region configured as a recess, wherein the first joining region and the second joining region are arranged on two opposing sides of an axle tube extending substantially along a tube axis, and wherein the axle tube can be secured by substance bonding in the first and second joining regions to the first and second suspension arm elements.
US10239373B2	Vehicle components and sacrificial ribs A structural component 1 is provided for a vehicle designed for driving off-road on rough terrain. The component 1, such as the lower control arm of a suspension system, is formed from aluminum, aluminum-alloy or other light-weight material and provided on its underside with a parallel arrangement of chamfered ribs 5 which extend in the direction of travel of the vehicle. The spacing between adjacent ribs 5 is less than or equal to 10 mm so as to prevent underlying rocks and stones 7 from impacting, and thereby abrading the inner surface 3 of the component 1. The ribs 5 are provided as sacrificial elements and will become eroded in use until they no longer provide the desired protection of the inner surface 3. The extent of abrasion of the ribs 5 can be ascertained by a visual inspection of the underlying surface of the vehicle, and, if necessary, the component 1 can be replaced.
US10239371B2	Lightweight pusher/tag axle A non-driven axle for a vehicle or a trailer is provided. The non-driven axle includes a first arm portion, a second arm portion, and a central portion. The first arm portion is for rotatably mounting a first wheel hub. The second arm portion is for rotatably mounting a second wheel hub. The second arm portion is on an axial end of the central portion opposite the first arm portion. The central portion is between the first arm portion and the second arm portion and may be substantially arch-shaped or substantially ring-shaped. The substantially arch-shaped central portion includes a main portion and a radially inner portion. The substantially ring-shaped central portion includes a main portion and an inner portion. The non-driven axle reduces a weight of a vehicle or trailer while capable of being lifted without interfering with an operation of a drive axle.
US10239368B2	Air maintenance tire and valve assembly A self-inflating tire assembly includes an air tube mounted within a tire sidewall groove. The air tube is in contacting engagement with opposite angled groove surfaces surrounding the air tube. A segment of the air tube is flattened from an expanded diameter to a flat diameter by bending and compression of the groove in a rolling tire footprint to force air evacuated from the flattened segment along a tube air passageway. A tube is positioned within the groove, wherein the tube has a circular cross-sectional shape and an outside diameter D, and the groove does not have a circular cross-sectional shape, wherein said groove has a width W and a length L, wherein D is greater than W.
US10239367B2	Method, apparatus and system for automatic detection of rim diameter A wheel parameter resolving system, apparatus and method are disclosed and described. The wheel parameter resolving system comprises a wheel unit configured to sense radial acceleration in a wheel, the wheel comprising a rim and a tire, the rim having a diameter, and a transmitter configured to transmit a transmit signal indicative of sensed radial acceleration, a controller configured to resolve a rotation parameter indicative of the rim diameter in response to the sensed radial acceleration, and a receiver configured to receive a receive signal based on a transmit signal indicative of sensed radial acceleration, the receiver communicatively coupled to the controller. Resolving the rotation parameter comprises calculating the rotation parameter based on the sensed radial acceleration and a predetermined roll parameter.
US10239365B2	Integrated wireless data system for a vehicle wheel hub assembly The present disclosure generally relates to an integrated wireless data system and method for mounting the system on one or more components within a vehicle wheel hub assembly for measuring operational data relating to the condition or status of a brake rotor or other components within a wheel hub assembly, where the integrated wireless data system rotates with the vehicle wheel.
US10239363B2	Tire with chafer and toeguard The present invention relates to a pneumatic tire having a pair of spaced apart bead components, a connecting carcass between the bead components, a pair of sidewalls overlying the carcass, and a rubber chafer portion adjacent to each of the sidewalls and positioned around at least a portion of each of the bead components and intended for contacting a rigid rim of a wheel, the rubber chafer portion comprising a radially innermost toe guard and a chafer adjacent to a radially outer end of the toe guard; wherein the ratio of a modulus of the toe guard to a modulus of the chafer is in the range of 3 to 10.
US10239361B2	Motorcycle tire for traveling on rough terrain and tire vulcanization mold To provide a motorized two-wheeled vehicle tire for traveling on uneven terrain, the block durability performance of which has been improved; and a tire vulcanization mold capable of molding said tire. A motorized two-wheeled vehicle tire for traveling on uneven terrain wherein multiple blocks are provided on the tread at intervals in the tire circumference direction. Recesses are provided on the bottom surfaces of the grooves. Multiple recesses are provided at intervals in the axial direction of the tire. Spew, which was drawn up into the vent holes of the mold during vulcanization molding, or removal marks thereof are provided between each recess and the block that is adjacent in the tire circumference direction.
US10239358B2	Pneumatic tire A pneumatic tire includes a tread portion provided with a first shoulder main groove, a second shoulder main groove and at least one main groove to separate a first crown portion and a second crown portion. The first crown portion is provided with first crown sipes with a width less than 2 mm, but is not provided with any grooves with a width equal to or more than 2 mm. The second crown portion is provided with second crown sipes having a width less than 2 mm, but is not provided with any grooves with a width equal to or more than 2 mm. Each first crown sipe extends from the crown main groove to the first shoulder main groove with a first inclination direction. Each second crown sipe extends from the crown main groove to the second shoulder main groove with the first inclination direction.
US10239354B2	Pneumatic tire The pneumatic tire (1) comprises at least three circumferential grooves (22) extending in a tire circumferential direction in a tread portion (2), and at least four ribs (23) defined by the circumferential grooves (22), the at least four ribs (23) extending in the tire circumferential direction. At least two of the ribs (23) protrude outward in a tire radial direction beyond the profile line (L) of the tread surface when viewed in the meridian cross section. The protruding amount (G) of the at least two ribs (23) decreases in order from a first side in a tire width direction to a second side.
US10239353B2	Pneumatic tire The pneumatic tire includes at least three circumferential main grooves extending in the tire circumferential direction and a plurality of land portions partitioned and formed by the circumferential main grooves. Also, the belt layer is formed by laminating a pair of cross belts having a belt angle, as an absolute value, of not less than 10° and not more than 45° and of mutually opposite signs, and a circumferential reinforcing layer having a belt angle within a range of ±5° with respect to the tire circumferential direction. Also, when viewed as a cross-section from the tire meridian direction, the distance Dcc on the tire equatorial plane from the circumferential reinforcing layer to the wear end surface and the distance De from the end portion of the circumferential reinforcing layer to the wear end surface have a relationship such that 1.06≤De/Dcc.
US10239348B2	Variable width wheel assembly Provided is a tire including rims, beads each mounted so as to surround each of the rims, a side wall that is connected to the beads, a sub-tread that is formed on top of the side wall and is formed of a material having elasticity so as to have a changing curvature, and plural tread blocks that are arranged on the sub-tread such that the distances between the tread blocks change in accordance with the change in the curvature of the sub-tread.
US10239346B2	Method of manufacturing a floor board A method of manufacturing a floor board comprises the steps of supplying a panel, printing a curable substance or surface removing substance onto the panel in a predefined pattern for creating an elevation on the panel at the pattern or removing a portion of the surface of the panel at the pattern, respectively, and curing the curable substance or removing any re-action products of the surface removing substance and the panel.
US10239343B2	Feeding pencil A feeding pencil includes a pipe member, a leading tube, a tubular main body, a movable body, and a holding member. The pipe member is disposed inside the leading tube and loads a drawing material. The movable body extends in an axial direction includes a male screw formed across an entire outer periphery thereof in the axial direction. The holding member holds the movable body. The pipe member includes a female screw on an inner surface thereof. The female screw screws with the male screw. A relative rotation between the leading tube and the main body relatively rotates the pipe member and the holding member and acts a screwing action between the male screw and the female screw. The screwing action moves the movable body forward to extrude the drawing material from the pipe member.
US10239340B2	Manual support for a multi-page document A hand held device for manually holding a multi-page document with a U-shaped element having a ring-shaped extension at one end of an elongated leg and a shorter leg parallelly spaced therefrom by a right angle extension at the opposite end of the elongated leg whereby the shorter leg is inserted between the pages along the inner side of the multi-page document's binding and the longer leg is positioned along the outer side of the multi-page document's binding such that a person can support the multi-page document with one hand by inserting, in part, a preselected finger of one hand through the ring-shaped extension.
US10239332B2	Printer, and printer control method A printing device interrupts printing a label and cutting the label of which printing was interrupted when the image printed on the label may be corrupted. The printer controller drives a printhead and conveyance unit to print labels. When the trailing end of the label paper is detected, whether or not a target label in the group of labels being printed can be conveyed so that the trailing end of said target label goes downstream from the printing position before the conveyance amount of the conveyance unit reaches a specific amount. If said conveyance is not possible, printing the target label by the printhead is interrupted, the conveyance unit is controlled to set the target label being printed to the cutting position, and the cutter mechanism is then controlled to cut the target label.
US10239330B2	Ink jet recording apparatus and ink jet recording method An ink jet recording apparatus includes an image forming unit configured to form an image containing a liquid and a coloring material on an ink receiving medium; a liquid absorbing member including a porous body that comes into contact with the image, the porous body being configured to absorb at least a part of the liquid from the image; and a plurality of pressure applying units configured to press the image on the ink receiving medium by the porous body. The plurality of pressure applying units include a first pressure applying unit configured to press the image at a first pressure and a second pressure applying unit configured to press the image having been pressed by the first pressure applying unit at a second pressure higher than the first pressure.
US10239326B2	Pre-treatment fixing fluid for an offset coated medium An example of a pre-treatment fixing fluid for an offset coated medium includes calcium propionate, calcium pantothenate, tetraethylene glycol, a surfactant having an HLB less than 10, an acid, and a balance of water. The calcium propionate is present in an amount ranging from greater than 4.5 wt % to 8.0 wt %, the calcium pantothenate is present in an amount ranging from about 2.0 wt % to equal to or less than 15 wt %, and the surfactant is present in an amount ranging from about 0.01 wt % to about 1.0 wt %, each based on the total wt % of the pre-treatment fixing fluid. The acid is present in an amount sufficient to render the pH from about 4.0 to about 7.0.
US10239319B2	Ink-jet recording apparatus An ink-jet recording apparatus of the present disclosure includes a recording portion, a cap unit, a wipe unit, and a lid member. The recording portion has a recording head. The cap unit is capable of reciprocating between a first position directly below the recording portion and a second position that is retracted in a horizontal direction from the first position, and has a cap portion that caps the recording head when at the first position. The wipe unit performs a recovery process with respect to the recording head. At the second position, the lid member is disposed above the cap unit and comes into tight contact with the cap portion.
US10239315B2	Liquid ejecting apparatus A liquid ejecting apparatus includes a liquid ejecting head that ejects a liquid supplied from a liquid supplier which has an engaging portion, a container that has an engaging-portion-receiving portion with which the engaging portion engages, and an attaching portion to which the container is detachably attached. The liquid supplier is detachably attached to the attaching portion with movement of the container in a state where the engaging portion has engaged with the engaging-portion-receiving portion. The engaging portion engages with the engaging-portion-receiving portion to be relatively movable in a direction which crosses a movement path of the container when the container is attached to the attaching portion.
US10239312B2	Liquid discharge head, liquid discharge device, and liquid discharge apparatus A liquid discharge head includes a plurality of nozzles from which a liquid is discharged, a plurality of pressure chambers communicating with the plurality of nozzles, respectively, a substrate in which the plurality of pressure chamber is arranged in a predetermined direction, a diaphragm provided on a first side of the substrate opposite a second side of the substrate facing the plurality of nozzles, the diaphragm forming walls of the plurality of pressure chambers, and a plurality of electromechanical transducer elements provided on the diaphragm corresponding to the plurality of pressure chambers, respectively. A groove is formed in the substrate on an end side of the plurality of pressure chambers in the predetermined direction, and the groove includes an opening that opens toward a direction opposite to the diaphragm.
US10239309B2	Image processing method, automatic image printing method, and automatic printing apparatus nozzle An image processing method includes a first step of matching the image to the target surface, a second step of dividing the target surface into a plurality of preliminary divided regions, a third step of acquiring a first preliminary divided region among the plurality of preliminary divided regions, a fourth step of dividing the target surface into a plurality of final divided regions, on the basis of a preliminary divided image included in the first preliminary divided region of the image matched to the target surface, and a fifth step of setting a print starting position for respective final divided images included in the plurality of final divided regions by using a boundary line that defines the plurality of final divided regions.
US10239308B2	Liquid discharge control apparatus, liquid discharge control method, and liquid discharge control program In order to reduce a density difference that appears when printing whose execution number of scan operations is changed is performed, a CPU acquires a plurality of color conversion LUTs; the CPU performs printing of each of normal portions of color patches using a reference LUT and performs printing of each of hitch portions of the color patches using a corresponding one of mutually different color conversion LUTs; the CPU allows a color patch having a small density difference to be input as a selection result; the CPU identifies a color conversion LUT corresponding to the selection result; and the CPU designates the color conversion LUT corresponding to the selection result as a color conversion LUT for the hitch portion.
US10239305B2	Three-dimensional laminating and shaping apparatus, control method of three-dimensional laminating and shaping apparatus, and control program of three-dimensional laminating and shaping apparatus A dissimilar material joined three-dimensional laminated and shaped object is shaped using a three-dimensional laminating and shaping apparatus. The three-dimensional laminating and shaping apparatus includes a material supplier that supplies materials of a three-dimensional laminated and shaped object to a shaping surface, an irradiator that irradiates the materials with a light beam, and a controller that controls the material supplier. The three-dimensional laminated and shaped object is a joined member obtained by joining dissimilar materials. The controller controls the material supplier to form a graded composition of the materials in a boundary region between the dissimilar materials of the three-dimensional laminated and shaped object.
US10239302B2	Layer-by-layer assembly of graphene oxide membranes via electrostatic interaction and eludication of water and solute transport mechanisms A method for synthesizing a water purification membrane is presented. The method includes stacking a plurality of graphene oxide (GO) nanosheets to create the water purification membrane, the stacking involving layer-by-layer assembly of the plurality of GO nanosheets and forming a plurality of nanochannels between the plurality of GO nanosheets for allowing the flow of a fluid and for rejecting the flow of contaminants. The method further includes cross-linking the plurality of GO nanosheets by 1,3,5-benzenetricarbonyl trichloride on a polydopamine coated polysulfone support.
US10239295B2	Elastomeric films having increased tear resistance Split-layer thermoplastic films having the structure A-(B-C)n-B-A, wherein A and C are inelastic layers each having a thickness and each comprising individually at least one of polymeric compositions A and C; B is an elastic layer comprising polymeric composition B, n≥1, and wherein the layers comprising (B-C)n-B have a combined thickness x, polymeric compositions A and C comprise an inelastic polymer; polymeric composition B comprises an elastomeric polymer; and the thickness of C comprises 5% or less of the total thickness of the film; and further wherein the film has a notched Elmendorf tear strength of at least twice the notched Elmendorf tear strength of a comparative thermoplastic film having the structure A-B-A, wherein A and B comprise substantially the same polymeric compositions A and B as the thermoplastic film, and wherein the B-layer of the comparative thermoplastic film has a thickness y which is substantially equal to x.
US10239293B2	Composite part The invention relates to a composite part, hereinafter also referred to as composite, which is produced by means of 2-component processing methods, preferably 2-component injection molding (2K injection molding), from at least one part composed of at least one polyamide molding composition additized with polybutadiene copolymer which is livid at room temperature and at least one part composed of at least one elastomer obtainable from rubber that is to be vulcanized or crosslinked with elemental sulphur, or is composed of these components after processing thereof.
US10239291B2	Multi-layered polymer film The present invention relates to a multi-layered polymer film, comprising a sealing layer and a base layer, wherein the sealing layer comprises a polypropylene (SL-PP), and wherein the sealing layer polypropylene SL-PP comprises comonomer units derived from ethylene in an amount of from 0.5 wt % to 25 wt % and from at least one C5-12 alpha-olefin in an amount of from 0.5 mol % to 4.0 mol %, and has an amount of xylene solubles XS of at least 20 wt %, and the xylene solubles have an amount of ethylene-derived comonomer units of from 4 wt % to 50 wt %.
US10239289B2	Multi-component composite structures A composite assembly that can be cured to form a multi-component composite structure which does not have micro cracks along the boundaries between the various components. The composite assembly includes a structural component and a moldable component wherein the coefficients of thermal expansion of the structural component and the moldable component at the interface or boundary between the two components are such that micro cracks do not form along the interface when the composite assembly is cured to form the multi-component composite structure.
US10239285B2	Spinning joining of similar and dissimilar materials A spin fastening system includes a first member and an adhesive layer applied to the first member. A second member is positioned in contact with the adhesive layer. At least a portion of the adhesive layer is cured after the second member is positioned in contact with the adhesive layer to render at least the portion of the adhesive layer substantially rigid. At least one spin fastener is inserted successively through each of the second member, the cured portion of the adhesive layer, and the first member.
US10239284B2	Meltfusion bonded absorbant structure comprising fibres and superabsorbant particles method for manufacturing such structure The present invention is an absorbent structure comprising a fibrous matrix (110), meltfusionable material and superabsorbent polymer particles (140). The absorbent structure is bonded by a meltfusion bond point (200) pattern, which is preferably created by ultrasonic welding.
US10239283B2	Fabric reinforced traction mat A traction mat wherein the foam is reinforced with a layer of fabric or fiber between the CLCC foam layer and the substrate or underlying surface. The layering is preferably a first foam layer, a first adhesive layer, a fabric and/or fiber layer, followed by a second adhesive layer. This prevents the CLCC foam from being bonded directly to the substrate which allows the fabric/fiber to support the CLCC foam such that the entire assembly can be removed in one piece without the CLCC foam disintegrating. The introduction of the reinforcing fabric and/or fiber layer eliminates any residual CLCC foam from being bonded to the substrate. Consequently, the traction mat can be easily lifted away and removed.
US10239281B2	System and method for pinning fiber material A process to create composite preforms and parts by stacking layers of two-dimensional fiber material (e.g., fiber cloth, fiber reinforced fabric, etc.) having pin-receiving holes and/or gaps disposed between the fibers of the fiber material is described. The stack is pinned together using a subset of pins, such as fiber reinforcing pins, inserted into a subset of the pin receiving holes and/or gaps, leaving at least some of the pin receiving holes and/or gaps available for pinning other layers, as layers of fiber material are added to the stack. As additional layers are added to the stack, different subsets of pins connect the additional layers to the stack, thereby building up the stack. Each layer of fiber material may have a different shape than the other layers and any arbitrary topology, potentially including non-convex and/or disjoint shapes. Furthermore, implementations may produce composite preforms having an arbitrary number of interconnected layers.
US10239280B2	Set of plates or parts obtained by cutting a block of metal or composite material The present invention relates to a set (1) of plates (2, 3; 12, 13; 21, 22; 41) or parts obtained by cutting a block (4, 4″, 4′″, 35) of metal or composite material extending around a plane (5) comprising a first plate (2, 12, 21, 41) or part having an upper face (7, 33) and is second plate (3, 13, 22) or part having a lower face (8). The upper face (7, 33) of the first plate (2, 12, 21, 41) or part has a surface (7, 330) having at least two lines of inflection or changing slope with respect to said plane (5), and the lower face (8) of the second plate (3, 13, 22) or part has a surface (8) with a shape complementary to the upper face (7, 33) of the opposite first plate (2, 12, 21, 41) at a more or less constant height, corresponding to the height of the cutting line (34) in the block (4,35).
US10239277B2	Flexible microsphere articles having high temperature stability There is provided an article a binder resin layer comprising an aliphatic polyurethane polymer comprising a plurality of soft segments, and a plurality of hard segments, where the soft segments comprise poly(alkoxy) polyol, and where the poly(alkoxy) polyol is essentially free of crosslinker; and a plurality of microspheres partially embedded and adhered to a first major surface of the binder resin layer, wherein the specific chemical identities and relative amounts of the segments and moieties of the aliphatic polyurethane polymer are sufficient to impart a glass transition temperature of 10° C. or less in the article and a storage modulus in the article that changes less than 15 MPa from 25° C. to 175° C.
US10239268B2	Tire mold and pneumatic tire Provided are: a tire mold including a bead portion molding surface for molding the bead portion of the tire, the bead portion molding surface having a ridge molding part including a recessed groove extending in the mold radial direction, the ridge molding part being formed in a flange contact portion molding region for molding a rim-flange contact portion of the tire; and a pneumatic tire, in which a bead filler has the tire radial direction outer end positioned more inward in the tire radial direction relative to the rim line position, and a ridge forming portion including a ridge extending in the tire radial direction is formed on the outer surface of the bead portion, the ridge forming portion being positioned in the rim flange contact portion.
US10239266B2	Method and apparatus for manufacturing contact lenses Apparatus and methods are described for manufacturing contact lenses employing dissolvable mold structure. The apparatus and methods involve approaches to dissolve at least portions of a mold and to separate a lens from the mold to present the lens for collection.
US10239264B2	Anti-counterfeiting measures for three dimensional objects A method and system of producing a three-dimensional object with an anti-counterfeiting measure uses a processor to access a data file including a plurality of parameters for producing a three-dimensional object, wherein the parameters comprise a plurality of structural parameters. The processor may also cause a three dimensional printing device to form the three dimensional object that exhibits the structural parameters by identifying a build material, identifying a concealment material, causing the three dimensional printing device to deposit a mixture of the build material and the concealment material in a plurality of layers, and causing the three dimensional printing device to cure the build material and concealment material to form the three-dimensional object with the anti-counterfeiting measure.
US10239263B2	Three dimensional printer A powder sintering lamination molding method which can improve the quality of the molded product without extending the time required for the lamination molding. A powder sintering lamination molding method, including the steps of, irradiating an irradiation region of the sliced layer of a molded product surrounded by an outline profile with a laser to selectively sinter the material powder of the material powder layer within the irradiation region; wherein a cooling period is provided after the laser is irradiated along the first line and before the laser is irradiated along the second line.
US10239260B2	Microwave bonding of EVA and rubber items Aspects of the present invention relate to systems and methods for customizing microwave energy distribution within a chamber to accommodate various load characteristics. Aspects of the present invention customized configurations of ports, deflectors, waveguides, conducting rods, and slots to shape and distribute energy.
US10239259B2	Custom insole A custom insole and process for fabrication comprised of scanning to map a foot, sending the scan to a remote processing computer and returning a 3D compatible printable file that can render the custom insole in a short time. The foot is preferably not deformed by standing pressure during the scan. The podiatrist taking the scan can amend the electronic file to add or remove material from the yet-to-be-made custom insole to tailor the fit to the specific patient.
US10239258B2	Techniques for optimizing orientation of models for three-dimensional printing In one embodiment of the present invention, a print orientation tool efficiently determines an orientation of a three-dimensional (3D) model such that, when 3D printed, the structural integrity of the resulting 3D object is optimized. In operation, the print orientation tool configures a stress analysis engine to slice the 3D model into two-dimensional (2D) cross-sections. The stress analysis engine then compute structural stresses associated with the 2D cross-sections. The print orientation tool translates the structural stresses to weakness metrics. Subsequently, the print orientation tool evaluates the orientations of the cross-sections in conjunction with the corresponding weakness metrics to select a printing orientation that minimizes weaknesses in the 3D model. Advantageously, by aligning the 3D model to the print bed based on the optimized printing orientation, the user mitigates weaknesses in the corresponding 3D object attributable to the 3D printing manufacturing process.
US10239257B1	Depositing portions of fiber-reinforced thermoplastic filament while alleviating torsional forces An apparatus and method for managing bending and other applied forces that are exerted on a filament of thermoplastic with reinforcing fibers in a 3D printing system during the deposition process that is associated with the manufacturing of an object. The quality of the manufactured object is enhanced through a process that comprises i) applying torque to certain portions of the solid filament in a manner that is commensurate with the expected motions of the deposition head while depositing those portions, but only after ii) heating each portion to a sufficient temperature. A heating device and a twisting device act on the filament while it is moving toward the deposition point and while under the control of a controller that is operating according to a computer model of the object being manufactured.
US10239254B1	Method of fabricating shape memory films A method for fabricating a shape memory polymer into a three-dimensional object is provided. The method includes forming a film of crosslinked poly(amic acid) on a substrate to provide a laminated substrate; forming the laminated substrate into a first configuration that is in a three-dimensional form; curing the cross-linked poly(amic acid) to provide the shape memory polymer having a permanent shape corresponding to the first configuration; and removing the substrate from the laminated substrate to provide the three-dimensional object comprising the shape memory polymer. The formation of the laminated substrate into the three-dimensional object may be based on origami techniques.
US10239251B2	Apparatus and method of forming a composite structure A drape forming apparatus for that includes a forming tool including an upper forming surface and a side forming surface extending from the upper forming surface. The forming tool receives a layer of composite material over the upper forming surface. The apparatus includes a flange forming device including an upper plate, a lower plate, and a receiving slot defined therebetween. The receiving slot receives a flange portion of the layer of composite material, and the flange forming device is translatable relative to the forming tool such that the flange portion of the layer of composite material is withdrawn from the receiving slot and draped over the side forming surface. The apparatus includes a pressurized bladder that extends over the forming tool and the upper plate. The pressurized bladder forces the flange portion against the side forming surface as the flange forming device translates relative to the forming tool.
US10239247B2	Methods for manufacturing bulked continuous filament A method of manufacturing bulked continuous carpet filament which, in various embodiments, comprises: (A) grinding recycled PET bottles into a group of flakes; (B) washing the flakes; (C) identifying and removing impurities, including impure flakes, from the group of flakes; (D) passing the flakes through a PET crystallizer; (E) passing the group of flakes through an MRS extruder while maintaining the pressure within the MRS portion of the MRS extruder below about 18 millibars; (F) passing the resulting polymer melt through at least one filter having a micron rating of less than about 50 microns; and (G) forming the recycled polymer into bulked continuous carpet filament that consists essentially of recycled PET.
US10239246B2	Injection molding machine An injection molding machine with an injection system and a clamping system. The injection system may include a removable injection module defining a portion of the material flow path. The injection module may include all of parts that come in contact with the material between the material source and the mold. The injection module may include a valve arrangement movable between a fill position to load the injection module with material and an inject position to eject material from the injection module into the mold. The actuators for the injection module may be supported on the machine rather than the injection module. The clamping system may include a platen linear actuator to open and close the mold, and a hydraulic clamping system to apply clamping force to the closed mold. The hydraulic clamping system may include a free-float valve manifold assembly that selectively places the hydraulic cylinders in free-float mode.
US10239245B2	Economical plastic tooling cores for mold and die sets A blemish free surface is formed on the cavity side of a set of mold or die blocks, said set consisting of a core side and a cavity side, by use of a softer alloy on the core side as contrasted to the cavity side so that, during plastic injection molding, the core side will wear at the parting line in preference to the cavity side whereby erosion of the set occurs on the core side in preference to the cavity side leaving the cavity side erosion free.
US10239244B2	Microbubble creating method using a forming machine A microbubble creating method using a forming machine for creating microbubbles by: installed a microbubble generating member in a mold, feed screw or barrel for enabling a perforated tip of the microbubble generating member to be surrounded by the applied fluid polymer so that when a high pressure high temperature gas is delivered through the perforated tip of the microbubble generating member, microbubbles are created with well mixed with the fluid polymer, and the expected foamed polymer product is thus obtained after cooling.
US10239241B2	Compacting and injection mold for a fiber preform for fabricating a turbine engine guide vane made of composite material A compacting and injection mold for a fiber preform is for use in fabricating a turbine engine guide vane out of composite material. The mold includes a shell forming a trough that is to receive the fiber preform and that is closed in leaktight manner by bottom and top covers, compacting blocks arranged inside the trough each having a surface pressing normally against a surface of the fiber preform that is to be compacted, and closure blocks arranged inside the trough. Each closure block has a surface pressing normally against a surface of a compacting block and does not have a surface in contact with the fiber preform.
US10239217B2	Magnet gripper systems Some embodiments provide a magnet gripper system, comprising: a gripper base comprising a magnetically attractive face; at least two slide plate retaining systems; and two or more slide plates wherein at least one of the slide plates is movably cooperated with each of the at least two slide plate retaining systems such that the slide plates are configured to move between a retracted position with the slide plates retracted relative to the face of the gripper base and an extended position with the slide plates extended relative to the face of the gripper base with an end of each of the slide plates being positioned further from the face of the gripper base when in the extended position than when the slide plates are in the retracted position.
US10239216B2	System for handling workpieces in a press line The system includes at least two industrial robots, each with a wrist and an auxiliary arm connected to the wrist by a respective first swivel joint, and a control unit for joint control of said robots; it further includes a crossbar connected at one end thereof to the auxiliary arm of one robot, and at another end thereof to the auxiliary arm of another robot, by a respective second swivel joint, the crossbar having at least two crossbar portions, each attached to the auxiliary arm of one robot and each arranged to carry a tool for picking workpieces, and the crossbar portions being linked to each other through a shifting arrangement such as to be displaceable one with respect to the other in their longitudinal direction.
US10239214B2	Device and method for releasing an operation of a machine A safety control device for releasing an operation of a machine, in particular a robot, includes an input device for detecting a manual contact, in particular a finger contact. The safety control device has a retaining device for securing the input device to a finger, in particular a fingertip, of an operator, in particular in a frictional manner, and/or a signaling means for outputting a signal, in particular an optical, acoustic, tactile, thermal, and/or electric signal, if a contact force detected by the input device is smaller than a specified upper minimum value and/or for outputting a signal, in particular the same signal or a different signal, in particular an optical, acoustic, tactile, thermal, and/or electric signal, if a contact force detected by the input device is greater than a specified lower maximum value.
US10239212B2	Ultrasonic tactile sensor for detecting clamping force An ultrasonic tactile sensor for detecting a clamping force includes an ultrasonic detector and a sensing layer, and the sensing layer includes a first soft layer and a second soft layer, and the first soft layer has plural spherical microstructures arranged in contact with the ultrasonic detector, so that after a pressure is applied to the sensing layer, the ultrasonic detector generates an ultrasonic wave and receives a reflected wave signal, and the signal is provided for identifying the contact area of the spherical microstructures and deriving the force exerted on the tactile sensor.
US10239211B2	Carrying method and bonding apparatus A laminate is directly transferred from a first robot arm that carries the laminate from a bonding chamber to an overlapping chamber, to a second robot arm that carries out the laminate from the overlapping chamber to the outside.
US10239209B2	Robot simulation device for human intervention-type robot system A robot simulation device, by which a calculation of a cycle time and a simulation of a human intervention-type robot system can be easily carried out with less effort by an operator. The simulation device has: an operation distributing part which distributes a plurality of operations to the robot and the human, based on a weight of an article to be worked in each operation, a conveying distance of the article, and a required time in each operation; a program generating part which generates a motion program for the robot and the human based on a result of distribution of operations obtained by the operation distributing part; and a cycle time calculating part which executes a simulation of the motion program and calculates a cycle time of the motion program.
US10239208B1	Determination of robotic step path A method for determining a step path involves obtaining a reference step path for a robot with at least three feet. The reference step path includes a set of spatial points on a surface that define respective target touchdown locations for the at least three feet. The method also involves receiving a state of the robot. The method further involves generating a reference capture point trajectory based on the reference step path. Additionally, the method involves obtaining at least two potential step paths and a corresponding capture point trajectory. Further, the method involves selecting a particular step path of the at least two potential step paths based on a relationship between the at least two potential step paths, the potential capture point trajectory, the reference step path, and the reference capture point trajectory. The method additionally involves instructing the robot to begin stepping in accordance with the particular step path.
US10239203B2	Movable closed-chain linkage for robot arm of media element storage library Utilities (e.g., systems, apparatuses, methods) that reduce robotic assembly contention in media element storage libraries by rotating (e.g., flipping, swinging, etc.) a robot arm of a first robotic assembly mounted over a first of first and second spaced storage arrays in a storage library into a first position between the first storage array and a central reference plane disposed between and parallel to the first and second storage arrays to allow a robot arm of a second robotic assembly to slide or otherwise move past the robot arm of the first robotic assembly (e.g., in a direction along or parallel to an x-axis parallel to the first and second storage arrays), even when the robot arms of the first and second robotic assemblies are disposed at the same height (e.g., along a z-axis that is perpendicular to the x-axis) within the storage library.
US10239201B2	Master-slave system A master-slave system (1) according to the present invention includes a slave actuator (As1 to As3) for generating a slave driving force (τs) to control a slave robot in terms of driving force, an effective driving force sensor (Fs1 to Fs3) for measuring a slave effective driving force (τsa) actually acting on a terminal output axis of the slave actuator (As1 to As3), and a slave target effective driving force calculating device (3) for calculating a slave target effective driving force (τsad) which is a target value for the slave effective driving force (τsa), on the basis of a master operating force (fm) applied to the master robot by an operator (U). The slave actuator (As1 to As3) generates the slave driving force (τs) on the basis of the slave target effective driving force (τsad) and the slave effective driving force (τsa).
US10239197B2	Post lock tool holder for L-shaped wrenches A tool holder holds one or more tools when not being used. The tool holder comprises a body with a plurality of tool retainers for removably receiving a tool and a plurality of posts for securing the tool within the tool holder body when the tool holder is in a closed configuration. In some embodiments, the tool retainers are holding tubes, pockets or slots. In order to couple a tool with the tool holder, a lock door is moved to an open position and the tool is inserted into a tool retainer of the tool holder. Then the locked door is moved to a closed position where it is positioned over the tool and the tool is secured within the tool holder. The tool is securely held within the tool holder body and is not removable when the tool holder is in the closed position. In some embodiments, the tool holder is configured to hold a L-shaped hexagonal or round tool. In some embodiments, the tool holder is able to hold a plurality of tools of different sizes.
US10239190B2	Release mechanism for clamping tools The present invention provides an improved release mechanism for clamping tools where problems of thread slipping due to worn out thread can be reduced by the structure of a plunger with a small diameter section and the engagement of the thread shaft is made more secure by the cam action on account of the shape of the plunger. A protrusion extends from a push button on a top portion of the half-threaded nut. Threads are formed on an upper portion of the hole for engaging the threaded shaft. The middle portion of the plunger is made to have a section of small diameter allowing the protrusion to be pushed downward in a normal position and allowing the protrusion to rely on the resilient power of the helical spring to push it upward into the small diameter section.
US10239186B2	System for internal air blasting of an enclosed space with an automated apparatus A system for internal air blasting of an enclosed space includes a ground vehicle, an arm supported by the ground vehicle, and a blasting nozzle provided at the end of the arm. The blasting nozzle being configured to direct blast media to a desired surface of the enclosed space to be treated by the arm. A method of internal air blasting an enclosed space is further disclosed.
US10239184B2	Abrading tool for a rotary dresser A roller assembly for a rotary dresser comprise a plurality of axial segments which may be in the form of discs, each disc provided with an abrasive, radially outer surface. The discs are secured in axial alignment, each in a preconfigured rotational orientation. The disc assembly has a centrally arranged aperture for receiving a rotor shaft. The abrasive surface of the assembly can be accurately presented as an array of uniformly shaped abrasive units in a predefined pattern.
US10239181B2	Double-station wheel burr removing device A double-station wheel burr removing device includes clamping drive systems, lifting drive systems, an upper rim burr removing system, a valve hole burr removing system, a rotary switching system and the like, which in use can simultaneously remove burrs on two wheels having different heights and different diameters at the end face of the upper rim, the valve hole, the lateral cutting position of the upper rim and the riser.
US10239179B2	Method for smoothing and/or polishing slabs of stone or stone-like material A method for smoothing and/or polishing slabs of stone or stone-like material suitable for being implemented with a machine comprising: a support bench (16) for a slab to be machined; and at least one machining station (14). The machining station comprises two bridge support structures (20, 22) arranged transversely astride the support bench (16). A spindle-carrying beam (24), in suitable for being moved above the bridge structures in a transverse direction, is provided on the bridge support structures (20, 22). At least one spindle-carrying structure (34), suitable for being rotated about its own vertical axis (32), is provided on the spindle-carrying beam (24). Each spindle-carrying structure (34) is provided with two motorized spindles (38A, 38B), the ends of which are provided with machining heads (42A, 42B) arranged spaced apart and opposite each other with respect to the vertical axis (32) of the spindle-carrying structure (34) and comprising machining tools (44A, 44B). The machine comprises a programmable computerized unit for controlling the position, movement and speed of the moving members. The method is characterized in that: —the beam and the spindle-carrying structures move coordinated and synchronized with each other; —for each stroke of the beam (24) in the transverse direction, each spindle-carrying structure performs a rotation of 180° about its axis of rotation (32); —when the beam (24) is located at the center line of the bench (16), the axis (60) connecting the rotation axes of the spindles (38A, 38B) is perpendicular to the longitudinal direction of the machine; and —when the beam (24) is located at the maximum distance from the center line of the bench (16), the axis (60) is parallel to the longitudinal axis of the machine.
US10239176B2	Method for evaluating tool installation, and machine tool Provided is a method for evaluating tool installation when fastening a tool to a main shaft of a machine tool, wherein the method includes a storage step for storing a reference location of a draw bar at the time when the tool is contacting a mounting seat of the main shaft, in a state in which foreign matter has been removed from the surface of the mounting seat and from the contacting surface of the tool. The method for evaluating tool installation includes a measuring step for measuring a measurement location of the draw bar when the tool is installed on the main shaft, and a determination step for determining the installation state of the tool to be abnormal if a measurement-location error with respect to the reference location exceeds a predetermined determination range.
US10239174B2	Machine tool The present invention provides a machine tool provided with a cover body having a simple structure, excellent operability, and low manufacturing cost. A tool post movement region one-side-closing cover part (9) for closing a tool post movement region open part (8) is configured so as to be: capable of expanding and contracting in a horizontal movement direction of a tool post (3); arranged facing the tool post (3); elongated by urging means (10) to press against the tool post (3) in a relatively slidable manner and close the tool post movement region open part (8); expanded and contracted by movement of the tool post (3) to hold the tool post movement region open part (8) in a closed state; and provided unconnected to the tool post (3) so that the tool post (3) is relatively slidable with respect to the tool post movement region open part (8) is held in a closed state.
US10239169B2	Steady rest A steady rest (1) for centering a rotationally symmetrical workpiece (2) in relation to a longitudinal axis of a processing machine, having, two housing shells (4, 5) separated by a distance from one another and connected together, an actuating piston (7) mounted in an axially moving arrangement in the housing shells (4, 5) which acts on the workpiece (2), three steady rest arms (8, 9, 10) mounted to the two housing shells (4, 5) in a swiveling arrangement by a bearing pin, and configured to move in concert so as to clamp the workpiece, wherein the clamping forces actually occurring on the steady rest arms (8, 9, 10) can be registered reliably using a force measuring device (21) provided on at least one of the two steady rest arms (8, 9), and passed onto an evaluation device (22).
US10239165B2	Eyebrow coil jacket, a heat control apparatus of a reactor using the eyebrow coil jacket, and a method for manufacturing the heat control apparatus Disclosed herein is an eyebrow coil jacket, a heat control apparatus of a reactor using the eyebrow coil jacket, and a method for manufacturing the heat control apparatus of the reactor. According to the present invention, it is possible to provide an eyebrow coil jacket that is capable of increasing the heat control area of the reactor even when applied to a large-sized reactor so that a heat control amount of the heat control apparatus is improved 20% more than when a half pipe coil is used, a heat control apparatus of a reactor using the eyebrow coil jacket, and a method for manufacturing the heat control apparatus of the reactor.
US10239162B2	Exothermic reaction welding molds, weld-metal containing cartridges for such molds, and methods of use Exothermic welding molds, weld-metal containing cartridges for such molds, and methods of use are provided. The mold, cartridges, and methods can provide interaction between the cartridge's disk member with the mold, which allows the housing member to be withdrawn from the mold while leaving the disk member and weld-metal in place. The interaction can be a rotational restraint alone, a vertical restraint alone, or combinations thereof. Alternately, the interaction can be an outward pressure on the housing member and/or disk member, a shear force on the housing member and/or disk member, or combinations thereof. The outward pressure on the housing member and/or disk member can alternately be provided without interaction between the disk member and the mold, but rather by the simple application of an internal pressure to the cartridge. The internal pressure can be applied by squeezing the walls of the cartridge and/or by depressing a pusher member.
US10239161B2	Stage for cutting substrate and substrate-cutting apparatus Provided are a stage for cutting a substrate and a substrate-cutting apparatus. The stage for cutting a substrate includes: a plurality of cell areas, each of the cell areas including a first opening; an edge area at an outer side of the cell areas, the edge area including a second opening having a diameter that is larger than a diameter of the first opening; a dummy area between adjacent ones of the cell areas; and a cutting groove between one of the adjacent ones of the cell areas and the dummy area or between one of the cell areas and the edge area.
US10239157B2	Additive machine utilizing rotational build surface An apparatus for manufacturing an axi-symmetric part. The apparatus includes a vessel configured to contain the powder. The vessel is also configured to receive a part such that at least a portion of the part contacts the powder contained within the vessel. A first energy source is configured to generate a first beam of energy. The first beam of energy is configured to melt the powder at a first predetermined location such that the melted powder fuses to the part.
US10239154B2	Laser welding method to weld two adjacent metal elements of a stator winding with rigid bars for an electric machine A laser welding method to weld two adjacent metal elements of a stator winding with rigid bars for an electric machine; the two metal elements are arranged one beside the other and have respective upper surfaces, which are arranged coplanar to one another and have at least one common edge; in succession, in the direction of the upper surfaces of the two metal elements, a first laser beam is aimed, which is fed along a first welding line, which is perpendicular to the common edge and extends through the common edge itself, and then a second laser beam is aimed, which is fed along a second welding line, which is perpendicular to the common edge and extends through the common edge itself, is parallel to and spaced apart from the first line and has a length that is smaller than the one of the first line.
US10239149B2	Device of electric sliding contact, welding head for roller welding machines and related roller welding machine A sliding electric contact device for welding head for roller welding machines, having a bimetallic plate adapted to be fixed to a shaft of a welding head, having a protection base composed of a first metal, defining a first face destined to abut against an end surface of the shaft, and a sliding disk composed of a second metal softer than the first metal, defining a second sliding electric contact face; a composite current-carrying block, having a plait of electrical wires, an internal support made of metal, pushed against the sliding disk for realizing with the sliding disk a sliding electric contact, first means adapted to fix firmly a central portion of the plait to the inner support, second current-carrying means adapted to fix firmly a peripheral portion of the plait to current terminals of a stator of the welding head. A welding head having the sliding electric contact device and a related roller welding machine are also disclosed.
US10239147B2	Sensor-based power controls for a welding system A welding system includes a torch motion sensing system associated with a welding torch and is configured to sense welding torch orientations or movements. The welding system also includes a processing system that is configured to vary operation of a power source based on the sensed orientations or movements.
US10239140B2	Systems and devices for performing powered threading operations A device and associated system for threading, cutting, and reaming pipe ends are described. The device and system utilizes a brushless DC electric motor. The devices also include on-board electronics and operator interface(s) to provide sophisticated control and information as to the various operations. Also described are methods of operating the devices and several different modes for performing various operations.
US10239138B1	Reciprocating saw blade for preparing fish This disclosure relates to a reciprocating saw blade for filleting and preparing fish. The reciprocating saw blade can comprise a blade and a wing. The blade can be attachable to a reciprocating blade. The blade can comprise a tip, a spine, a cutting edge and a heel. The spine can be at one side of the blade. The spine can have a concave form from the tip up to the middle side edge section of the blade and can form a straight edge from the middle section up to the rear side edge section of the blade. The cutting edge can have a continuous set of serrations formed through a tooth from a plurality of teeth. The cutting edge can comprise a grind that divides the spine and the cutting edge. The grind can taper from the middle section of the blade to the cutting edge.
US10239136B2	Circular saw apparatus with integrated multistage filtration system Various dust collection apparatuses are disclosed, which include a vacuum source, a circular saw blade, and a worktable comprising a center slot axially aligned to the circular saw blade. In a first aspect, the center slot includes an air flow channel proximate to an anticipated point of contact between the circular saw blade and a workpiece, and the vacuum source is configured to provide a focused negative pressure beneath the worktable via the air flow channel. In another aspect, the vacuum source provides a negative pressure beneath the worktable at the center slot, and a multistage filter is included to collect airborne dust drawn by the negative pressure from an area proximate to the center slot. In yet another aspect, the vacuum source is configured to provide a first negative pressure beneath the worktable at the center slot, and a second negative pressure via an auxiliary port.
US10239134B2	Tool body and cutting tool The present invention relates to a tool body provided with at least one insert seat. The insert seat includes a bottom wall surface and a side wall surface. The side wall surface includes a first side wall surface and a second side wall surface. The first side wall surface includes at least two surface portions. The first surface portion is a curved surface having a recessed shape recessed toward a base end of the tool body, and the second surface portion is a curved surface having a recessed shape recessed toward the base end of the tool body, with a greater curvature radius than that of the first surface portion, or a flat surface. The two surface portions both come into contact with a cutting insert.
US10239131B2	Machine tool, in particular multi-spindle milling machine The present invention relates to embodiments of a machine tool, in particular a multi-spindle milling machine, comprise a machine frame, a workpiece clamping device for clamping a workpiece, an axis slide assembly arranged on the machine frame, and a spindle carrier assembly which is arranged on the machine frame and has at least two tool-carrying work spindles. The axis slide assembly is configured to linearly move the workpiece clamped at the workpiece clamping device by way of three controllable linear axes X, Y and Z. The work spindles are arranged at a turret which can be rotated or swiveled about a turret axis at respectively equal distance from the turret axis, and the spindle axes of the work spindles are aligned or can be aligned in parallel to one another and in parallel to the turret axis.
US10239130B1	Guide device for a cutting tool A guide device comprising a hollow body configured to receive a drill bit, the hollow body having a first end; a second end; and a continuous section intermediate the first end and the second end; an opening extending from the first end through the continuous section to the second end; and at least one aperture located on the hollow body intermediate the first and second end of the hollow body.
US10239127B2	Locking chuck A chuck has a body (14). A plurality of first teeth (96) are rotationally fixed to the body. At least one second tooth (100) opposes the first teeth. The first teeth and the at least one second tooth are configured so that engagement of the first teeth and the at least one second tooth prevents relative rotation between a nut (16) and the body in an opening direction. A sleeve (18) defines a notch (90b) that engages a spring (29) so that in a relative rotational position between the sleeve and the nut, the notch receives the spring so that the notch resists relative rotational movement between the sleeve and the spring in the opening direction of the chuck.
US10239123B2	Cutting insert having two peripheral abutment ridges and cutting tool A cutting insert includes an insert longitudinal axis defining a forward to rear direction, opposing insert inner and outer side surfaces and an insert peripheral surface extending therebetween. The insert peripheral surface includes an insert rear end surface and an adjacent insert lower surface. The cutting insert includes two spaced apart peripheral abutment ridges that are distal the insert outer side surface and extend along the insert rear end surface and the insert lower surface, respectively. The two peripheral abutment ridges converge towards each other at an acute insert wedge angle in a rearward direction of the cutting insert, away from a cutting edge.
US10239121B2	Clay-like composition for sintered precious metal body A clay-like composition for forming a sintered precious metal body, the clay-like composition containing at least one powder selected from the group consisting of precious metal powders and precious metal alloy powders, an organic binder, an organic additive and water, wherein the clay-like composition has an initial hardness measured using a type E durometer of E8 to E20, and has a hardness after standing for one hour at room temperature of E40 or less.
US10239120B2	Casting methods and molded articles produced therefrom Molded articles and methods for forming molded articles are provided. For example, a molded article comprises a first region formed by a first casting material and a second region formed by mixing a molten or liquid portion of the first casting material and a second casting material. The first casting material is a molten, liquid, or fluid metal alloy, and the second casting material is a molten or fluid metal alloy. The first casting material has a different chemical composition than the second casting material. The first region and the second region are cast as one integral casting using directional solidification, and the first region and the second region have different microstructure patterns. The molded article has a lower concentration of impurities than were present in the first and second casting materials, and an interface between the first region and the second region is devoid of an oxidation layer.
US10239113B2	Net shaped forging for fluid ends and other work pieces An embodiment includes a method for net shape forging of a manifold block, comprising: starting with a single bar having a first cross-sectional area, placing a work piece area of the single bar in a die; and upsetting, via longitudinal movement of the single bar, the work piece area of the single bar in the die, wherein the single bar is pressed into the die to reduce its length; whereby the work piece area of the single bar is displaced to an increased cross-sectional area as compared to the first cross-sectional area. Other aspects are described and claimed.
US10239112B2	Method of reducing cycle time for flow drill screw operations A method of reducing the cycle time required for flow-drill screw operations by providing a dimple on a part that is engaged by a flow-drill screw. A tip of the flow-drill screw engages a contact band at a location spaced from the tip of the distal end of the flow-drill screw and base portion of the dimple. Friction between the flow-drill screw tip and dimple creates a heat concentration area and results in displaced material forming a threaded sleeve. The flow-drill screw is secured by the threads of the threaded sleeve to secure the top part to the bottom part.
US10239106B2	Spinning method and spinning apparatus A spinning method includes supporting a supported portion of a cylindrical work by a work supporting portion; pressing a first roller of a spinning head against a processed portion of the work while revolving the first roller; and performing a forming process that points a tube axis of the processed portion of the work in a given direction by pressing the first roller and a second roller in which a plane of revolution thereof is provided in a different position, in a rotational axis direction of a spindle of the spinning head, than a plane of revolution of the first roller, while revolving the first roller and the second roller, and moving the work supporting portion relative to the spinning head or moving the spinning head relative to the work supporting portion, while the first roller and the second roller work in cooperation with each other to retain the work.
US10239103B2	Material testing method, use of a drawing die arrangement, and drawing die arrangement A method for material testing of an elongated work piece drawn through a drawing die arrangement, wherein the drawing die arrangement includes a drawing tool that acts on the elongated work piece, forming it in a forming region, carries out the material testing in the forming region.
US10239102B2	Rolling rod as an inner tool in the production of seamless metal hollow bodies and method for producing a metal hollow body A rolling rod configured as an inner tool in the production of seamless hollow bodies, such as seamless pipes. The rolling rod has a nitrided surface layer and may consist of a heat-resistant steel material having a chromium equivalent calculated by a formula, as well as has a minimum hardness, yield point and tensile strength. A seamlessly hot-rolled, metallic hollow body is produced by a stretch-forming procedure in a multiple-stand rolling mill via the rolling rod which is threaded into the hollow block. Prior to threading the rolling rod into the hollow block, the rolling rod is provided with a liquid lubricant and is subsequently dried. The rolling rod is threaded in with a clearance with respect to the inner diameter of the hollow block. Prior to threading-in the rod, the hollow block may have an average temperature of at least 1000° C., with the rod having a determined speed.
US10239099B2	Working surface cleaning system and method A cleaning film designed to remove foreign matter and particulates from working surfaces of cleaning wafers used in semiconductor processes. These processes include wafer sort test for cleaning of probe card pins and FEOL tooling for cleaning during wafer handling equipment and wafer chucks. The debris collected on the cleaning wafer working surfaces is removed by the particle removal film allowing the debris and foreign matter to be discarded. The use of the cleaning film allows the operator to refresh the cleaning wafer without use of an outside vendor and eliminates wet washing and the use of solvents in the cleaning process.
US10239098B2	Air shower room and dust-free workshop Disclosed is an air shower room. The shower room comprises a chamber, an air supply apparatus, an air exhaust apparatus, a sensing mechanism and a controller. The sensing mechanism is disposed at a height inside the chamber and operable to detect presence of the user's arm at the height. The height is chosen such that the user has to raise his arm such that the presence of the arm at the height can be detected by the sensing mechanism. The controller is configured to control operations of the air supply apparatus and the air exhaust apparatus based on the detection by the sensing mechanism. Also disclosed is a dust-free workshop.
US10239095B2	Grill brush assembly with removable brush Embodiments set forth a cleaning brush handle that includes a head region that includes one or more brush apertures, where each brush aperture is configured to receive one replaceable brush. The brush apertures may be orthogonal to the brush handle, or, in the alternative, may be at an angle in the longitudinal direction, the transversal direction, or both. The brush includes a nominally ¼″ round or hex-shaped shank that is inserted into the brush aperture. The brushes are held in place via a suitable mounting mechanism, such as a threaded insert that receives a thumbscrew or a bushing with a threaded hole that receives a thumbscrew. The mounting mechanism provides for easy insertion, rotation, removal, and replacement of the brushes. The mounting mechanism provides for rotating the brushes, in small increments, through a 360° range, for more even brush wear and longer brush life, relative to conventional cleaning brushes.
US10239094B2	Systems and methods for scanning information from storage area contents The present invention is related to methods and systems for collected item information for stored items. In one embodiment, a networked food storage system comprises a first sensor configured to read information from item tags coupled to items, wherein the items are stored or intended to be stored in a storage unit. A data store is configured to store food preferences for at least a first user. Instructions, stored in computer readable memory, are configured to: cause a first user interface to be displayed to the first user via which the first user can request a meal suggestion; retrieve preference information for the first user from computer readable memory; retrieve information read from at least a first item tag; and provide a meal suggestion based at least in part on preference information for the first user and item tag information.
US10239093B2	Ultrasound transducer assembly and method for manufacturing an ultrasound transducer assembly The present invention relates to an ultrasound transducer assembly (10), in particular for intravascular ultrasound systems. The ultrasound transducer assembly comprises at least one silicon substrate element (30) including an ultrasound transducer element (14) for emitting and receiving ultrasound waves and including electrical connectors for electrically connecting the transducer element. The substrate element has a top surface (44), a bottom surface (46) and a side surface connecting the top surface and the bottom surface. An isolation layer (32, 50) forms the side surface for electrically isolating the substrate element.
US10239090B2	Method and apparatus for coating a substrate utilizing multiple lasers while increasing quantum yield A method and an apparatus are disclosed for coating a substrate with a coating, or a coating powder. The substrate is divided into a number of target fields which are scanned by a plurality of lasers after the target fields have been pre-heated by a separate laser. A closed loop, real time servo system is employed for monitoring the coating process. Based upon monitoring of the target field, as the coating, or coating powder, is applied, real time changes to the parameters of the lasers provide for a uniform coating of the substrate.
US10239088B2	Fluid application system adapted to collect and reuse reclaimed fluid A fluid application system includes a source of a fluid and a first pump for supplying the fluid under pressure to an applicator having a nozzle for dispensing the fluid. A fluid collection system collects reclaimed fluid dispensed from the applicator and a second pump provides the reclaimed fluid under pressure to a return fluid pipe. The return fluid pipe has a valve system that selectively directs the reclaimed fluid to either a reusable fluid container or the applicator. The valve system may selectively direct the reclaimed fluid from the return fluid pipe to an in-line reservoir and a third pump may be used to provide the reclaimed fluid under pressure from the in-line reservoir to the applicator.
US10239078B2	Powdered scent compound A powdered scent compound and related methods of application for adhering the powdered scent compound to a desired application area. The powdered scent compound can comprise a porous carrier powder, an adhesive compound and a synthetic scent compound. The powdered scent compound is shelf-stable and convenient to apply, carry and store. Furthermore, the powdered scent compound can adhere to applied surfaces, thereby ensuring that powdered scent compound remains where it is applied, even in locations where the potential exists for the compound to drip or be blown from.
US10239074B2	Hose guns A hose gun has a gun body and a water outlet head for outputting water from the gun. The gun body has a user grip body portion and a second body portion which is at an angle to the user grip portion. Joint means are provided between the water outlet head and the gun body allowing the water outlet head to be moved relative to the gun body between a forward watering position and a sprinkler position in which the hose gun is positionable on a surface with the user grip body portion and second body portion acting as a base and the water outlet head directed upwardly.
US10239072B2	Energy dissipation unit for high voltage charged paint system A grounding dissipation unit for a paint delivery apparatus for delivering paint is disclosed. The paint delivery apparatus includes a first paint line for carrying paint from a canister, a second paint line for carrying paint to an ionizing applicator for electrically charging paint, a first water line for carrying water to a grounding source, a second water line carrying water to the grounding dissipation unit, and a third water line for carrying water to a dump. The grounding dissipation unit includes a core made of an electrically conductive material. A paint bore in the core connects the paint lines, and a water bore in the core connects to the water lines to ground the system. The paint bore and water bore do no intersect within the core.
US10239069B2	Agricultural skin grafting A method of forming a material structure from structural units contained within a liquid solution in a spray head is described. The liquid solution includes a solvent and a solute, the solute comprising a plurality of the structural units, the structural units including monomer units, oligomer units, or combinations thereof. The method comprises forming droplets of the liquid solution including the structural units, and spraying the droplets on a substrate, thereby substantially increasing the reactivity of the structural units within the droplets relative to the structural units within the liquid solution in the spray head. The increase in reactivity can result from the droplets containing an excess of a particular ion, the ion excess resulting from a voltage applied to conductive walls of the device which dispenses the droplets. The material structure is then formed on the substrate from the more highly reactive structural units within the droplets.
US10239065B2	Flow control component and shower A flow control component comprises a water inlet pipe, and a shower equipped with the flow control component. A partition formed with water holes which are different in aperture is disposed in the middle of the water inlet pipe; a first rotating block with a water diversion opening and a main water opening respectively formed at two ends is installed in an inner hole of the water inlet pipe; a first water passage which communicates with the water diversion opening and the main water opening is disposed in the middle of the first rotating block. The water inlet pipe is externally sleeved with an adjusting sleeve; a toggle pin passes through a radial arc-shaped hole on an outside face of the water inlet pipe; the adjusting sleeves drives the first rotating block to rotate through the toggle pin such that the water diversion opening selectively communicates with the water holes.
US10239054B2	FCC counter-current regenerator with a regenerator riser A counter-current catalyst regenerator with at least two stages of counter-current contact along with a regenerator riser is proposed. Each stage may comprise a permeable barrier that allows upward passage of oxygen-containing gas and downward passage of coked catalyst into each stage, but inhibits upward movement of catalyst to mitigate back mixing and approximate true counter-current contact and efficient combustion of coke from catalyst. The regenerator riser may provide a passage to transport the catalyst and may serve as a secondary stage for coke combustion to provide the regenerated catalyst.
US10239049B2	Alloyed zeolite catalyst component, method for making and catalytic application thereof The presently disclosed and claimed inventive concept(s) generally relates to a solid catalyst component comprising a zeolite with a modifier and at least one Group VIII meal alloyed with at least one transition metal. The presently disclosed and claimed inventive concept(s) further relates to a method of making the solid catalyst component and a process of converting mixed waste plastics into low molecular weight organic compounds using the solid catalyst component.
US10239045B2	Inorganic composite oxides and methods of making the same Described herein are methods for forming inorganic composite oxides. Such methods include combining, at a substantially constant pH of between about 5 and about 6.75 over a period of at least about 5 minutes, an acidic precursor composition and a basic composition to form a precipitate composition, wherein the acidic precursor composition comprises an alumina precursor, a ceria precursor, a zirconia precursor and optionally one or more dopant precursors; stabilizing the precipitate by increasing the pH of the precipitate composition to between about 8 and about 10; and calcining the stabilized precipitate to form an inorganic composite oxide. Also described are inorganic composite oxides formed using such methods.
US10239038B2	Systems and methods for a cooled nitric oxide generator Systems and methods for a nitric oxide (NO) generation system are provided. In particular, the present disclosure provide an NO generation system that is configured to be cooled to maintain an NO generator of the system at or below temperatures safe for patient use and contact. In some non-limiting examples, the NO generation system may include a pump configured to furnish a fluid (e.g., a gas) toward and/or through the NO generator to provide cooling thereto.
US10239033B2	Reactor system and use thereof A reactor system (1) having a reactor 3, at least one cooler (5) connected to the reactor (3), at least one pump (7) for circulating at least some of a liquid heat-transfer medium (9), wherein the pump (7) is connected to the reactor (3) and/or the at least one cooler (5), and a container (11) for collecting the liquid heat-transfer medium (9) is provided. The container (11) is connected to the reactor (3) and/or the at least one cooler (5) and is disposed substantially below the reactor (3) and/or the at least one cooler (5). Also provided are exothermic reactions which are conducted in the reactor system.
US10239032B2	Unit for chlorine dioxide generation and chlorine dioxide generation device The present invention provides a chlorine dioxide generation unit that can release practically sufficient amount of chlorine dioxide for an extended period of time while being compact. The present invention provides a chlorine dioxide generation unit, characterized in that said unit comprises an agent storage space portion and at least two light source portions, said light source portion is for generating light consisting of wavelengths substantially in the visible region, said agent storage space portion stores an agent comprising solid chlorite, and said agent storage space portion comprises one or more openings so that air could move in and out of said agent storage space portion, wherein chlorine dioxide gas is generated by irradiating said light generated from said light source portion onto said agent present inside said agent storage space portion.
US10239029B2	Aeration device An aeration device includes a housing; a pump module mounted inside the housing and configured to provide a fluid flow; a tube connector mounted inside the housing and fluidly connected to the pump module; an aerator tube configured to be attachable to the tube connector; and a gripping recess mounted inside the housing such that the aerator tube is receivable within the gripping recess. The aerator tube is configured to receive the fluid flow from the pump module and deliver the fluid flow to a liquid in a vessel. The aerator device is configured to rest on a top rim of a vessel during operation of the pump module.
US10239027B2	Device for producing lithium sulfide, and method for producing lithium sulfide An apparatus for producing lithium sulfide, including: a reaction container for allowing lithium hydroxide powder to be in contact with a hydrogen sulfide gas; a stirring blade inside the reaction container; a first heating apparatus that keeps the temperature of an inner wall of the reaction container that is in contact with the powder; and a second heating apparatus that keeps the temperature of an inner wall that is not in contact with the powder.
US10239020B2	Water treatment system and water treatment method A water treatment system according to an embodiment of the present invention includes a tank that stores water to be treated, a crossflow filtration membrane module that filters the water to be treated, a supply passage through which the water to be treated is supplied from the tank to the filtration membrane module by using a supply pump, and a recirculation passage through which the water to be treated, the water having passed through a membrane upstream side of the filtration membrane module, is recirculated to the tank. The tank has an upper space above a liquid surface of the stored water to be treated, the upper space being hermetically filled with an inert gas. The water treatment system further includes a gas transport passage through which the inert gas is introduced from the upper space into the supply passage or the filtration membrane module, and a compressor that is disposed in the gas transport passage and that pressurizes the inert gas. The compressor is preferably a water-sealed compressor.
US10239016B2	Systems and methods for nitrogen recovery from a gas stream Methods of producing a treated gas by removing nitrogenous compounds are disclosed. Methods of recovering ammonia from a gas stream having nitrogenous compounds are disclosed. Methods of producing a fertilizer product from organic waste are disclosed. The methods may include introducing aqueous sulfurous acid into a gas stream having nitrogenous compounds to absorb the nitrogenous compounds in a liquid and produce a treated gas. The methods may also include maintaining the pH of certain solutions above 5 or introducing an oxidant into certain solutions to produce sulfate ions. Systems for removing nitrogenous compounds including a reaction subsystem, a solids-liquid separator, a temperature control subsystem, an oxidation control subsystem, and a recirculation line are also disclosed. The systems may be employed to remove nitrogenous compounds from a gas stream, recover the ammonia from the gas stream, or produce a fertilizer product from the recovered ammonia.
US10239015B2	Apparatus and method for separating carbon dioxide with self recycle loop This invention relates to a device for separating carbon dioxide that includes a self-recycling loop, and to a method of separating carbon dioxide, which serve to effectively separate carbon dioxide from a combustion gas using a separation membrane provided with the self-recycling loop. This invention adopts a self-recycling loop in which the residue gas passing through a specific separation membrane is introduced into another separation membrane and in which a permeate gas passing through the specific separation membrane is introduced back into the specific separation membrane. Accordingly, the concentration of carbon dioxide in the feed gas of the specific separation membrane is increased, which increases the concentration of the permeate gas to thus improve the separation performance of the separation membrane, thereby separating high-purity carbon dioxide.
US10239014B2	Carbon capture solvents and methods for using such solvents A solvent for recovery of carbon dioxide from gaseous mixture, having alkanolamine, reactive amines acting as promoter or activators, glycol, and a carbonate buffer. A solvent for recovery of carbon dioxide from gaseous mixture, having alkanolamine, reactive amines acting as promoter or activators, sulfolane, and a carbonate buffer. One specific solvent contains less than about 75% by weight of water and has a single liquid phase.
US10239013B2	Process for recovering methane from a gas stream comprising methane and ethylene The invention relates to a process for recovering methane from a gas stream comprising methane and ethylene, comprising a sorption step which comprises contacting the gas stream comprising methane and ethylene with a sorption agent which has a lower affinity for methane than for ethylene, resulting in sorption of ethylene and 0 to 90% of the methane by the sorption agent and in a gas stream comprising methane in an amount of 10 to 100% based on the amount of methane in the gas stream that is subjected to the sorption step; and a desorption step which comprises desorbing sorbed ethylene and optionally sorbed methane resulting in a gas stream comprising ethylene and optionally methane.
US10239012B2	Methods of separating molecules Disclosed herein are new methods, machines, processes, and systems for separating molecules by determining better materials and process optimization conditions. As a result of these advances, this disclosure provides improved carbon dioxide capture, better flue gas treatments, and more efficient methods of purifying gases have been developed. Optimal sorbents can be obtained by using a computational screening method that selects microporous structures (e.g. zeolites and metal-organic frameworks) from a database of materials with the greatest potential for cost-effective separations. The disclosed methods are the first to consider both the size and shape of the adsorbent material. This is also the first disclosure to consider the process application and cost when selecting which material to use.
US10239009B2	Continuously-operable flow stream processing system and method A continuously-operable flow stream processing system and method has two or more fluid processing media arranged in a fluid conduit network to provide alternate flow paths for a flow stream to be processed (e.g. filtered). Valves and other flow control devices, e.g. controller module and sensors, are used to redirect the flow stream from one or more service-needed fluid processing media to service-ready fluid processing media without taking the system offline to remove, repair, replace, clean in situ, or otherwise service the service-needed fluid processing media, so that the system may operate continuously to process the flow stream without stoppage. Redirection into alternative flow paths and media may be automatically implemented based on a predetermined threshold or trigger condition, such as may be detected by sensors directly or indirectly monitoring media condition.
US10239006B2	Polymer nanofiber structural body and method of producing the same A polymer nanofiber structural body of the present invention is a polymer nanofiber structural body in which polymer nanofibers are integrated, including a first layer and a second layer different from each other in polymer nanofiber existence ratio, in which: both the first layer and the second layer are laminated through a buffer region; the buffer region includes a region in direct contact with both the first layer and the second layer; and a polymer nanofiber existence ratio of the region continuously changes from a polymer nanofiber existence ratio of the first layer to a polymer nanofiber existence ratio of the second layer in a direction from the first layer to the second layer.
US10238999B2	Filtering assembly comprising a filter cartridge The present invention relates to a filtering assembly (1) for filtering at least one fluid circulating in particular in an engine or a hydraulic device, comprising: a filter body (2), which comprises a vessel (3) and a head (4), the vessel (3) and the head (4) being provided to engage with one another in order to close the filter body (2), in particular by screwing; a tube (15), in particular a central tube, which is inside the filter body (2) and extends along a longitudinal axis (X); a removable filtration cartridge (16,) which is accommodated in the filter body (2) and includes an upper end plate (20), a lower end plate (21) and a filtration medium (22) which extends between the upper (20) and lower (21) end plates, the filtering medium (22) having a tubular opening (17) for surrounding the tube (15), characterized in that the upper end plate (20) comprises first reversible rigid-connection means (25) and in that the vessel (3) comprises second reversible rigid-connection means (26) which are complementary to the first reversible rigid-connection means (25), such as to enable the filtration cartridge (16) to stay in position in the vessel on the one hand, and in the filtering assembly (1) on the other hand, only by rigidly connecting the first and second reversible rigid-connection means (25, 26).
US10238997B2	Embedded influent diffuser for floating media filter A floating media filter including a filter housing with an influent conduit extending into the filter housing, the influent conduit having at least one outflow aperture positioned below an effluent outlet of the filter housing. A floating media is positioned in the filter housing and forms a media bed when the filter is in a filtration stage, the media bed having a lower surface and an upper surface defining a filtration zone between the lower and upper media bed surfaces during the filtration stage. A diffuser trough is positioned in the filter housing such that (i) the lower surface of the media bed, when the filter is in the filtration stage, is below an upper edge of the diffuser trough, and (ii) the outflow aperture of the influent conduit is positioned sufficiently close to a surface of the diffuser trough such that influent flow, during the filtration stage, is initially directed against and/or along the surface of the diffuser trough, and then redirected in a path into the media bed. Finally, the media filter includes a backwashing mechanism causing (i) lowering of the upper surface of the media bed to a point below the upper edge of the diffuser trough, and (ii) creation of an air space in a substantial portion of the filtration zone.
US10238992B2	Processes for analysis and optimization of multiphase separators, particularly in regard to simulated gravity separation of immiscible liquid dispersions The present invention is directed to systems and methods for evaluating performance, performing process control, optimization and design of gravity separation process systems that are used to separate immiscible liquid dispersions (e.g., water-in-oil, oil-in-water mixtures) and emulsions for two-phase (liquid-liquid) or three-phase (gas-liquid-liquid) systems. According to one aspect, the design, simulation and control of such systems is performed using computational fluid dynamics (CFD) software that is configured for determining the separation efficiency of separators on the basis of the true geometry and multidimensional flow field and for a distribution of droplet sizes with the influence of the emulsion concentration on the rheology of the oil-in-water or water-in-oil dispersion. The results of the CFD simulations can be used to adjust input parameters of the separator to maximize the separation efficiency of the separator such that it outputs liquid streams containing minimal amounts of immiscible liquid dispersions.
US10238987B2	Alkylation system and a process for cooling a vent stream One exemplary embodiment can be a process for cooling a vent stream from a receiver. Generally, the process may include providing a refrigerant including at least one compound contained in the receiver so the refrigerant leaking into the receiver can be compatible with the process.
US10238982B2	Throw-and-catch based toy with free fall sensing, impact sensing, and speaker output A throw-and-catch based toy with free fall sensing, impact sensing, and speaker output which includes a system, method and device for detecting a pre-determined motion from an accelerometer, comparing a sensed accelerometer information to a pre-determined accelerometer signature information, producing a sound based on the comparison of sensed accelerometer information to a pre-determined accelerometer signature information.
US10238981B2	Assembly with object in housing and mechanism to open housing In an aspect, a toy assembly is provided, and includes a housing, an inner object, at least one sensor and a controller. The inner object is positioned inside the housing and includes a breakout mechanism that is operable to break the housing to expose the inner object. The at least one sensor detects interaction with a user. The controller is configured to determine whether a selected condition has been met based on at least one interaction with the user, and to operate the breakout mechanism to break the housing to expose the inner object if the condition is met. Optionally, the condition is met based upon having a selected number of interactions with the user.
US10238977B2	Collection of marketing information developed during video game play A system and method for collecting information related to a video game including a physical object such as a toy. The system includes a game console having a processor for executing instructions to conduct video game play using the physical object. During the game play, data related to the toy may be stored for on the physical object or game console and provided to a server.
US10238972B2	System and method of modeling the behavior of game elements during a remote game Disclosed are systems and methods for modeling behavior of game elements during a remote game between at least two users. The system includes a positioning module configured to determine parameters for at least two game elements representing physical objects, and game manipulators that detect a physical action performed by a user in order to exert a force action on at least one game element and calculate one or more physical parameters characterizing the physical action. The system further includes a module for performing force actions that determines the game element to be subject to the detected physical action and perform a force action on the determined game element. The system further includes a control module that determines behavior parameters for the game elements characterizing a change in state of the game elements, and a visualization module that generates a behavior model of the game elements.
US10238969B2	Recording medium storing game program, game processing method, and information processing apparatus A terminal apparatus includes a storage device that stores state information of game contents changing according to progress of a game; a screen information generator that generates first information relating to a display of the game contents on a display screen and second information relating to a display of the state information on the display screen; an output device that outputs the first information and the second information to the display screen at a predetermined timing, respectively; and an instruction receiving device that receives a switching instruction to switch between display of the game contents and display of the state information on the display screen, wherein the screen information generator generates the second information based on latest state information stored on the storage device at a time when receiving the switching instruction.
US10238963B2	Adjustable tension thumbstick A thumbstick for a user input device comprises an adjustable tensioning mechanism configured to modify a tilt tension of a tiltable post. The thumbstick comprises a cap with a stem that defines a first cavity. A base is moveable with the tiltable post and comprises a portion extending into the first cavity. The portion defines a second cavity and comprises a protuberance projecting into the second cavity. An adjustment body within the second cavity comprises a recessed slot and a contacting surface at a distal end. The slot is configured to engage the protuberance to adjust the tilt tension of the tiltable post.
US10238956B2	Versatile fantasy sport scratch-off ticket and method A scratch-off fantasy sport gaming ticket has: a ticket support sheet; two or three distinct regions of images on one side of the ticket support sheet; a first region providing a random distribution of symbols indicating a number of distinct sports events which the ticket can use; a second region of images providing either i) a random distribution of multiple symbols indicating one sports team or player on which the ticket can be used with the number of distinct sports events; a third region providing a random distribution of symbols indicating a sports statistic to be associated with both the multiple symbols indicating the number of distinct sports events and the sports team or player; and each of the two or three visually distinct regions of images have an opaque scratch-off coating over them, or ii) a second region having both events and statistical target in each distinct region.
US10238954B2	Hand-forming card shuffling apparatuses including multi-card storage compartments, and related methods Card shufflers usable in forming and dispensing randomized playing card hands for use in playing card games include a card input mechanism for inputting cards into the card shuffler, a card storage device for receiving cards from the card input mechanism and temporarily storing cards within the card shuffler, and a card output mechanism for outputting shuffled cards from the card shuffler. The card storage device may include a wheel configured to rotate within the card shuffler. The rotatable wheel may have a plurality of card storage compartments therein, each of which may be sized and configured to hold two or more cards therein. Related methods involve the use of such card shufflers in playing card games.
US10238951B2	Batting pad for adjusting location of bat in batter's hand A batting pad comprising a body made from a cushioning material and having a ring portion adapted to fit over a batter's thumb and an appendage to cushion the palm area between a batter's thumb and index finger. The appendage has a thickness T at its thickest point located between the first end and the distant end, and the thickness T of the appendage is selected to optimize an angle of a bat in the batter's hand relative to a line parallel to the batter's forearm, the angle being determined by the thickness T of the appendage displacing the bat toward the tip of the batter's index finger and causing the bat to contact the palm of the batter's hand near the batter's little finger.
US10238949B2	System and method for displaying a baseball batter count A method for depicting a batter count box on a display is provided. The method includes the steps of employing a plurality of pixelated sections, with the plurality of pixelated sections including a pixelated balls section and a pixelated strikes section within the batter count box.
US10238944B1	Basketball goal dock A docking tray for receiving a basketball goal includes: (a) a base having a front, a rear, and two sides, the front being wider than the rear and the two sides narrowing from front to rear; (b) two side walls extending upwardly along the sides of the base; (c) a rear wall extending upwardly along the rear of the base, the base, side walls, and rear wall forming an enclosure for a rear wheel of a basketball goal; and (d) a retainer for engaging, orienting, and securing a base of a basketball goal.
US10238943B2	Multiple sensor tracking system and method A system and method for tracking the flight of golf balls at driving range. The system includes a plurality of hitting stations, a plurality of sensors, a computer, and a range surface. Each hitting station in the plurality of hitting stations includes a golf ball, a golf club, a monitor, and a sensor. At least one other sensor in the plurality of sensors is placed outside a hitting station. The flight path of the golf balls being calculated by the computer using parameters by the plurality of sensors. The method includes steps for determining whether a first sensor detected a first parameter and a second parameter, whether a second sensor detected a first and a second parameter, whether a third sensor detected a third parameter, and depicting the flight path of the golf balls using the first parameter, the second parameter, and the third parameter.
US10238942B2	Snowboard trainer A snowboard trainer (SBT) includes an SBT platform, a slide rail, slide supports, a central stand, and a front interface. The slide rail extends from a first end to a second end. The slide supports connect the slide rail to the SBT platform. The slide supports are configured to support the slide rail relative to the SBT platform. The central stand is positioned relative to the slide rail on the SBT platform and positioned between the first end and the second end of the slide rail. The central board receiver is connected to the central stand. The front interface is configured to be secured to a front portion of a snowboard. The front interface includes a roller bearing sized to be retained in the central board receiver such that when the roller bearing is received in the central board receiver, the front interface three-dimensionally rotates relative to the central stand.
US10238941B2	Basketball net which detects shots that have been made successfully A made-shot-detecting net system is configured to determine when a basketball passes through the net. The system uses a strand of conductive material that is laced through the net, an electrical property (e.g., resistance) of which changes (e.g., increases) as the net—and hence the strand of conductive material—is stretched. By filtering out steady-state components of a voltage signal obtained from the net, instances where the net is being stretched can be identified. A value obtained by integrating (i.e., summing) the voltage output over the course of a stretch event is compared to various thresholds to identify the nature of the event. In certain embodiments, the fact that a shot has been made is transmitted wirelessly to a basketball-performance tracking application running on a mobile electronic computing device.
US10238939B2	Configurable water mat A water mat assembly having selectively attachable modular panels is disclosed. The water mat comprises a buoyant solid core insert that is inserted into a sleeve made of fabric. The sleeve may be couple to other sleeves to form an assembly of floating panels. The end panels may have grommeted ports for tethering the mat assembly to a dock or water vehicle.
US10238936B2	Golf ball and tee setting and retrieval device A device for setting a golf ball and tee. The device includes an upper handle portion connected to a lower gripper portion by an elongated tubular stem portion, the upper handle portion including a pivotal trigger member. The lower gripper portion includes a pair of jaw members pivotal about a pin member. A cable member is located within the elongated tubular stem portion and communicates the pin and trigger members, allowing the normally open jaw members to be brought together to hold a golf ball and tee upon activation of the trigger member. A stand member is attached to the elongated tubular stem portion adjacent its lower end, and includes a spike member extending downwardly therefrom. A golf ball stop member configured to prevent contact between a golf ball and the upper portions of the jaw members extends between the jaw members.
US10238935B2	Golf bag bottoms and methods to manufacture golf bag bottoms Embodiments of golf bag bottoms and methods to manufacture golf bag bottoms are generally described herein. Other embodiments may be described and claimed.
US10238933B1	Golf club head having adjustable stress-reducing structures A golf club head comprising a body and a plurality of adjustable stiffening members is disclosed herein. The body comprises a face section, a sole section, and a crown section or a return section, and also defines a hollow interior. Each of the plurality of stiffening members is at least partially disposed within the hollow interior, and extends from the crown section or return section to the sole section to reduce stresses placed on the face during impact with a golf ball. The stiffening members, each of which comprises a rod and a tube, may be adjusted to be in compression or tension, thereby preloading the body and affecting the stresses experienced by the golf club head upon impact with a golf ball.
US10238932B2	Golf club with milled striking face A golf club is disclosed that has a golf club head with a face having peaks or ridges and deep grooves or valleys. The deep grooves or valleys promote improved “feel” and/or reduced “smash factor” which may be particularly desirable when the golf club head comprises a putter face. The deep grooves or valleys may eliminate the need for costly soft metal alloy faces and/or polymeric or other resilient inserts between the face and the body of the golf club head.
US10238931B2	Golf club head manufacturing method Methods of bifurcating the material properties of golf club heads, and wedges in particular, are disclosed herein. The methods of the present invention preserve the bendability and feel of certain parts of the club heads, such as hosel regions, while selectively hardening and increasing the durability of other features, such as scorelines and texturing on the face.
US10238928B2	Golf club A golf club head includes a golf club body including a sole, a crown connected to the sole by a skirt, and a hosel connected to at least one other feature of the golf club body; a face connected to the a front end of the golf club body; and features allowing striking of a golf ball above the ideal strike location.
US10238927B2	Golf club heads with apertures and methods to manufacture golf club heads Embodiments of golf club heads with apertures and methods to manufacture golf club heads are generally described herein. Other embodiments may be described and claimed.
US10238925B2	Golf club head or other ball striking device having impact-influencing body features A ball striking device, such as a golf club head, has a face with a striking surface configured for striking a ball and a channel extending across a portion of the sole. The channel may be recessed from adjacent surfaces of the sole and have a depth of recession from the adjacent surfaces of the sole, wherein the channel comprises a center portion extending across a center of the sole, a heel portion extending from a heel end of the center portion toward the heel, and a toe portion extending from a toe end of the center portion toward the toe, wherein the width and the depth of the center portion of the channel are substantially constant, and wherein the depth of the channel is greater at the heel and toe portions than at the center portion.
US10238920B2	Golf ball An object of the present invention is to provide a golf ball showing increased controllability on approach shots for less than 40 yards and showing excellent shot feeling. In the inventive golf ball, the paint film is formed from a curing type paint composition including: a base material containing a polyrotaxane, and a curing agent containing a polyisocyanate, and wherein the polyrotaxane has a cyclodextrin, a linear molecule included in a cyclic structure of the cyclodextrin in a manner of piercing through the cyclic structure of the cyclodextrin, and a blocking group located at both ends of the linear molecule to prevent disassociation of the cyclodextrin, and at least a part of hydroxyl groups of the cyclodextrin is modified with a caprolactone chain via —O—C3H6—O— group.
US10238915B2	Method to determine body's physiological response to physical exercise for assessing readiness and to provide feedback, and system for implementing the method The invention relates to a method and a system for determining body's readiness to respond to physical exercise and for providing feedback to a user. In the method the user starts to perform an exercise, an earlier performance level is determined before starting a performance check having steps of: an instant performance level of the user is determined, the earlier performance level is compared to the instant performance level, a readiness index is determined according to the said comparison and optionally with background and/or training history of the user, a feedback is given according to the determined readiness index.
US10238914B2	Incentive spirometer for sustained maximal inspiration An incentive spirometer is provided that allows a user to achieve Sustained Maximal Inspiration (SMI) through the use of helical tubes. Specifically, the incentive spirometer includes three chambers, wherein each chamber includes a ball traveling upwards through three helical tubes in sequential order and subsequently dropping down through a basket. Here, each of the helical tubes and corresponding baskets generally represent various levels of lung capacity achieved with repetitive use and operation of the incentive spirometer.
US10238913B1	Limiting structure for a body-training device A limiting structure for a body-training device includes a base, a positioning shaft, and a controlling member. The base comprises a slidable sleeve and the base is fixed on the foundation. The slidable sleeve has a shaft hole. The pivot holder of the body-training device has a positioning portion aiming at the shaft hole. The positioning shaft passes through the shaft hole. When a frame of the body-training device is standing, the positioning shaft can be slid to connect to the positioning portion so as to limit the pivot holder not to swing laterally. The controlling member is assembled on the frame and combined with the positioning shaft to control the positioning shaft to be slid to connect to the positioning portion or to be slid to detach from the positioning portion.
US10238912B2	Curved treadmill A curved treadmill has a frame assembly, a handrail assembly, and a belt assembly. The frame assembly has a support frame, two arced guide tracks, two cushions, multiple guide wheels, and multiple positioning wheels. Each arced guide track is concaved downward. The cushions are mounted on the arced guide tracks. The guide wheels are mounted on the support frame. The positioning wheels are mounted between two ends of the support frame. The belt assembly includes two connection belts and multiple pedals. The connection belts are wrapped around the guide wheels, and one side of each connection belt abuts the positioning wheels. The pedals are mounted on the connection belts and optionally abut the cushions. Therefore, with the cushions, impacts may be absorbed and noises may be reduced. Besides, by abutting the positioning wheels, the connection belt may not be distorted sideward, and the noises are reduced further.
US10238911B2	Motorized treadmill with motor braking mechanism and methods of operating same A treadmill includes a running belt defining a non-planar running surface, and a motor operatively coupled to the running belt. The treadmill is operable in plurality of operating modes to control a user experience.
US10238910B2	Multi-axis adjustable exercise machine A multi-axis adjustable exercise machine which is pivotable about both a pitch axis and a roll axis with respect to a base for allowing an exerciser to perform a wide range of exercises on a pitched or rolled exercise machine. The multi-axis adjustable exercise machine generally includes an exercise machine which is adjustable with respect to a base. The exercise machine may be pivoted about a roll axis to adjust the roll angle of the exercise machine or may be pivoted about a pitch axis to adjust the pitch angle of the exercise machine. One or more actuators may be connected between the base and the exercise machine to effectuate the pivoting of the exercise machine about either or both axes with respect to the base.
US10238908B2	Acceleration trainer A training device includes a tether having inelastic portions disposed between its ends, where each inelastic portion is separated by an elastic portion, and where each of the ends is configured for engagement with hands of a trainer. The training device may include a belt that wraps around an athlete's body, the belt including a ring on a back portion thereof having an opening for receiving an end of the tether therethrough. When the belt is secured around the athlete's body and the tether is disposed through the ring, the training device may create a coupling between the trainer and athlete when the trainer secures the ends of the tether. The coupling may be substantially released when the trainer releases one end of the tether such that the released end is substantially unrestrained to traverse through the ring thereby fully disengaging the tether from the belt.
US10238906B1	Gluteus maximus exercise device An exercise device for targeting the gluteus maximus muscle uses a stand to hold up a bellows pump against a vertical surface while a user repeatedly pushes the pump with a foot. The pump has a one-way inlet valve and a small restrictor opening to allow air to leave the bellows slowly, providing a mechanism for selecting different resistance values. A catch is used to keep the pump in the compressed position during storage.
US10238905B2	Lacrosse Training Device A sports training apparatus for practicing lacrosse comprising an elongate rigid member extending along a length between first and second ends, first and second stops secured to the elongate rigid member, and a slidable mass on the elongate rigid member, slidable along the elongate rigid member between the first and second stops. A kit for retrofitting a lacrosse stick for practicing lacrosse comprising first and second stops, securable to a lacrosse stick; and a slidable mass, having a passage along an axis there through. The instant abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.
US10238902B2	Expulsion of a fire suppressant from a container Disclosed herein is an example method for expelling a fire suppressant from a container into a distribution manifold. The method includes generating a propellant gas that flows into the container via a first port of the container, thereby causing a pressure within the container to increase. The container includes the fire suppressant prior to the generation of the propellant gas. The method further includes, in response to the pressure within the container exceeding a threshold pressure, expelling the fire suppressant from a second port of the container into the distribution manifold. The generated propellant gas continues to flow into the container via the first port at least until substantially all of the fire suppressant included within the container prior to the generation of the propellant gas is expelled from the container via the second port. Example fire suppression systems are also disclosed herein.
US10238900B2	Aiming tool for nozzles A tool for aiming a nozzle assembly having a fluid outlet and a cap is provided. The tool includes a housing defining a bore. The bore has a side wall radially disposed about an axis. The tool also includes a laser assembly including a laser emission source configured to produce a light beam collinear with the axis of the housing. The laser assembly also includes a power supply. The tool further includes at least one of a switch and an electrical contact provided within the housing and adapted to be in electrical communication with the power supply and the laser emission source based on a contact with the nozzle assembly. The tool is installed on the nozzle assembly such that the bore is adapted for placement about an outer surface of the nozzle assembly so that the fluid outlet is substantially concentric about the axis.
US10238899B1	Systems and methods for supporting an operator from a building A suspension system for supporting an operator from a parapet of a building has first and second support assemblies adapted to engage the parapet, a first support line extending from the first support assembly to the first operator, and a second support line extending from the second support assembly to the first operator. At least one of the first and second support assemblies engages the parapet to support the operator relative to building. To allow the operator to move relative to the building, the weight of the operator is supported by one of the first and second support assemblies while the other of the first and second support assemblies is moved.
US10238895B2	Ultrasound catheter system An ultrasonic system operable at high drive frequencies and/or in pulsed operation is disclosed. The system may be used in a procedure to treat an occluded blood vessel. The system can be used to transmit ultrasonic energy from an ultrasonic transducer to a distal end of an ultrasonic transmission device. The ultrasonic device may operate at a resonant frequency. The resonant frequency can be determined prior to using the device and/or during use. The ultrasonic device may operate in a range of frequencies at or near resonance. Operational parameters including, for example, reflected vibrations, temperature, and/or user input can be used by the system to adjust the driving waveform.
US10238894B2	Energy based fat reduction Methods for non-invasive fat reduction can include targeting a region of interest below a surface of skin, which contains fat and delivering ultrasound energy to the region of interest. The ultrasound energy generates a thermal lesion with said ultrasound energy on a fat cell. The lesion can create an opening in the surface of the fat cell, which allows the draining of a fluid out of the fat cell and through the opening. In addition, by applying ultrasound energy to fat cells to increase the temperature to between 43 degrees and 49 degrees, cell apoptosis can be realized, thereby resulting in reduction of fat.
US10238892B2	System and method for patient-specific radiotherapy treatment verification and quality assurance system A radiotherapy treatment verification and quality assurance method may include receiving at least one set of first medical images of at least a portion of a patient. A three-dimensional model of the portion of the patient may be created based on the at least one set of first medical images. At least one dosimeter may be inserted into at least a portion of the model. The dosimeter is configured to measure exposure to radiation. The model may be irradiated in accordance with a radiotherapy treatment plan created by a treatment planning system. A readout of the model may be taken or performed to measure in three-dimensions a delivered radiation doses distribution.
US10238888B2	Altering a condition of an object using magnetic arrays A device used for treating an object can include a body having multiple mounting surfaces. The device can also include at least three magnets disposed on the mounting surfaces, where each magnet includes a first end and a second end, where the first end has a first polarity, where the second end has a second polarity, and where the first polarity attracts the second polarity to create a magnetic field, and where the magnets create a number of magnetic fields that intersect at a target area. At least one of the magnets can include a core material, and at least one component of the core material is carried by the magnetic field to the target area, where the at least one component core material is used to treat the object.
US10238886B2	Treatment of cancer or tumors induced by the release of heat generated by various chains of magnetosomes extracted from magnetotactic bacteria and submitted to an alternating magnetic field A method for the treatment of tumor(s) or tumor cell(s) or cancer(s) in a subject in need by the generation of heat. The latter is produced by chains of magnetosomes extracted from whole magnetotactic bacteria and subjected to an alternating magnetic field. These chains of magnetosomes yield efficient antitumoral activity whereas magnetosomes unbound from the chains or kept within the whole bacteria produce poor or no antitumoral activity. The introduction of various chemicals such as chelating agents and/or transition metals within the growth medium of the bacteria improves the heating properties of the chains of magnetosomes. Moreover, the insertion of the chains of magnetosomes within a lipid vesicle is also suggested in order to favor their rotation in vivo and hence to improve their heating capacity. The vesicle can contain an antitumoral agent together with the chains of magnetosomes. In this case, the agent is released within the tumors by heating the vesicle.
US10238880B2	Medical devices having deformable structures providing medical lead fixation Medical devices include deformable structures that contact a lead upon being compressed. A grip that a clinician may grasp and manipulate is engaged with a nose structure of a header block of the medical device, and manipulation of the grip causes compression of the deformable structure to ultimately create fixation of the lead within the header block.
US10238874B2	Implantable lead An implantable wireless lead includes an enclosure, the enclosure housing: one or more electrodes configured to apply one or more electrical pulses to a neural tissue; a first antenna configured to: receive, from a second antenna and through electrical radiative coupling, an input signal containing electrical energy, the second antenna being physically separate from the implantable neural stimulator lead; one or more circuits electrically connected to the first antenna, the circuits configured to: create the one or more electrical pulses suitable for stimulation of the neural tissue using the electrical energy contained in the input signal; and supply the one or more electrical pulses to the one or more electrodes, wherein the enclosure is shaped and arranged for delivery into a subject's body through an introducer or a needle.
US10238873B2	Spinal cord stimulation with interferential current A stimulator and a method for the treatment of intractable pain syndromes by electrical stimulation of the spinal cord is disclosed in which implantable electrodes positioned around a targeted area of the spinal cord transmit an interferential current that has a base medium frequency alternating current between 500 Hz-20 KHz. A digital signal processor generates a sine-wave-like waveform from a pulse generator which after further processing is used to generate at least two circuits for use in producing the beat frequency signal. An effective area of stimulation is controlled by the quantity of electrodes, positioning of the electrodes and electrode cross pattern orientation. Amplitude modulation of electrical circuits created at the electrode placements also augments the effective area of stimulation. The stimulator and method reduce accommodation of the body to the electrical stimulation and provide deeper penetration of the resultant signal.
US10238866B2	Iontophoresis device with multi-electrode end piece The invention relates to an end piece intended for equipping a device for cosmetic treatment of keratin materials with an electric current, the end piece comprising an application member (6) comprising an electrode (1) and a counter electrode (2), said electrode (1) and counter electrode (2) being separated from one another by an electrically insulating zone (3).
US10238862B2	Extracranial implantable devices, systems and methods for the treatment of medical disorders The present disclosure relates to methods, devices and systems used for the treatment of medical disorders via stimulation of the superficial elements of the trigeminal nerve. More specifically, minimally invasive systems, devices and methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.
US10238860B2	Method and apparatus for improved wound healing A pad for electrically stimulated wound healing, including a pad configured to be placed on a wound, at least one anode disposed on the pad to contact the wound, and at least one cathode disposed on the pad to contact the wound, the at least one cathode being disposed separately from the at least on anode. The pad wherein the at least one anode and the at least one cathode in contact with the wound provide a flow of electrical current in an intended direction through the wound based on the separate locations of the at least one anode and the at least one cathode.
US10238859B2	Non-invasive magnetic or electrical nerve stimulation to treat or prevent autism spectrum disorders and other disorders of psychological development Devices, systems and methods are disclosed for treating or preventing an autism spectrum disorder, a pervasive developmental disorder, or a disorder of psychological development. The methods comprise transmitting impulses of energy non-invasively to selected nerve fibers, particularly those in a vagus nerve. The nerve stimulation may be used as a behavior conditioning tool, by producing euphoria in an autistic individual. Vagus nerve stimulation is also used to modulate circulating serotonin levels in a pregnant woman so as to reduce the risk of having an autistic child; modulate the levels of growth factors within a child; promote balance of neuronal excitation/inhibition; modulate the activity of abnormal resting state neuronal networks; increase respiratory sinus arrhythmia; and avert episodes of motor stereotypies with the aid of forecasting methods.
US10238858B2	Connector and infusion set A connector includes a housing including: an insertion section into which a male connector is insertable from an outside of the housing, and a flow path communicating with the insertion section; and an elastic valve body having a slit and configured to block the insertion section. An inner wall of the housing defining the flow path is integrally formed with a liquid barrier face. The housing is configured such that, when the male connector is inserted in the insertion section, the liquid barrier face faces a tip opening of the male connector in an insertion direction of the male connector such that liquid flowing out from the tip opening collides with the liquid barrier face.
US10238853B2	Methods and systems for establishing retrograde carotid arterial blood flow Devices and methods establish and facilitate retrograde or reverse flow blood circulation in the region of the carotid artery bifurcation in order to limit or prevent the release of emboli into the cerebral vasculature such as into the internal carotid artery. The methods are particularly useful for interventional procedures performed through a transcarotid approach or transfemoral into the common carotid artery.
US10238852B2	Septum housing A catheter assembly may include a catheter adapter, a septum housing, and a septum. The catheter adapter may include a distal end, a proximal end, an inner wall extending between the distal end and the proximal end, and a lumen formed by the inner wall. The septum housing may include one or more protrusions and may be secured to the inner wall by one or more of the following: an interference fit between the one or more protrusions and the inner wall, a snap fit between the one or more protrusions and the inner wall, and bonding between the one or more protrusions and the inner wall. The septum may be at least partially disposed within the septum housing and configured to at least substantially seal the lumen.
US10238847B2	Devices and methods for transdermal drug delivery Provided are devices for therapeutic interaction with an Abreu brain thermal tunnel (ABTT) terminus. Such devices are configured to provide one or more drugs to an ABTT terminus, and may provide heat to or remove heat from the ABTT terminus while providing the one or more drugs.
US10238842B2	Device for the trans-anal drainage of stool from the rectum of a patient and/or for the trans-anal application of inflowing liquid through a catheter-like element A device for emptying stool from the rectum of a patient by means of a shaft body which is introduced into the bowel via the anus and is able to buckle or fold axially and radially, and which is provided with a dumbbell- or hourglass-shaped balloon body for assuring the transanal positioning of the device. The invention comprising a design of, and choice of material, for the shaft body and the balloon envelope, and by the positioning of the balloon body on the shaft body, wherein the axial deflection of the free forward end of the shaft body is limited and an uncontrolled deflection of the shaft is prevented, and the probability of perforation of the bowel wall under the effect of force acting on the shaft body from an axial direction is reduced by the intestinal tube.
US10238840B2	Catheter assembly A catheter assembly includes a hollow catheter; a catheter hub configured to fix and hold the catheter; an inner needle including a needle tip and configured to be removably inserted through an inside of the catheter; a needle hub configured to fix and hold the inner needle; and a catheter operation member capable of moving the catheter relative to the inner needle. The catheter operation member includes a holding portion configured to directly hold the catheter in a detachable manner.
US10238837B2	Catheters with control modes for interchangeable probes A medical system including a catheter containing a mechanical system that is remotely operable uses a sensor to at least partly measure a pose of the catheter and a control system coupled to the mechanical system. The control system has multiple operating modes including one or more holding modes in which the control system operates the mechanical system to maintain a working configuration of the catheter based on feedback from the sensor.
US10238830B2	Continuous anesthesia nerve conduction apparatus, system and method thereof The invention generally relates to a continuous anesthesia nerve conduction apparatus and method thereof, and more particularly to a method and system for use in administering a continuous flow or intermittent bolus of anesthetic agent to facilitate a continuous or prolonged nerve block. In one embodiment, the apparatus includes a sheath having a proximal end, a distal end and at least one lumen extending from the proximal end to the distal end. The sheath also includes an embedded conductive element for transmitting an electrical signal from a proximal portion of the sheath to a distal portion of the sheath. A cannula is arranged in the at least one lumen of the sheath and has a distal end protruding from a distal portion of the sheath. The cannula is electrically coupled to at least a portion of the embedded conductive element and is configured to provide nerve stimulation.
US10238822B2	PAP system A PAP system is adapted for treatment of respiratory disease or sleep disordered breathing. The PAP system includes headgear, a patient interface and a flow generator. The flow generator includes a blower adapted to provide pressurized breathable gas to a patient through the patient interface. The blower is at least partially vibrationally isolated from the patient's head by at least one foam layer mounted within the flow generator to secure the blower. The at least one foam layer is adapted to reduce the amount of transmitted vibration received by the patient. The flow generator further includes a mounting structure limiting an extent of a compression of the at least one foam layer due to the weight of the blower. The mounting structure includes at least one protrusion extending from an interior surface of the flow generator toward the blower.
US10238819B2	Dry powder inhaler and inhalation actuated mechanism thereof A flap (20) for an inhalation actuated mechanism (18) of a powder inhaler (1) comprises a base member (29), a skirt structure (24) projecting from a surface of the base member (29), and a coupling portion (21) to be coupled to a resilient member (40′) of the inhalation actuated mechanism (18).
US10238814B2	Applicator for cryoanesthesia and analgesia A handheld cryoanesthesia or analgesia device for cooling a target area on cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone having an elongated body and a thermoelectric cooling system disposed within the elongated body. The thermoelectric cooling system is configured to physically contact and thermally couple the target area of the cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone to induce cryoanesthesia or analgesia. The thermoelectric cooling system includes a thermally-conductive cold tip, a thermally-conductive cooling power concentrator thermally coupled to the cold tip, at least one Peltier unit module thermally coupled to the cooling power concentrator, a heatsink thermally coupled to at least one Peltier unit module, a power source, at least one thermal sensor, and a controller operably outputting a control signal to the Peltier unit module to maintain a predetermined temperature.
US10238813B2	Dispensing device with control body in order to axially move a dispensing element A dispensing device includes a container with a receiving space containing a dispensable medium extractable via a dispensing element. A control body (19) with a connecting body (11) is longitudinally displaceable in a housing part (9), from an inactive base position to an active extraction position by a rotational movement. A media-carrying connection is created between the receiving space and the dispensing element. A control part of the control body (19) can be attached to a control path (54) of the connecting body (11). When the control body (19) moves rotationally relative to the housing part (9), each control part follows the rotational movement in an axially unchanged manner and brings the connecting body from the base position to an extraction position via each associable control path (54) of the connecting body (11). The control path comprises a slope.
US10238811B2	Medical needle removal and storage device An apparatus for removing a needle from a needle holder, including a grasping unit for selectively grasping the needle; a receiving unit for receiving the needle holder, displaceably disposed relative to the grasping unit; a biasing member biasing the receiving unit in a first direction; and separating means for separating the entire needle from the needle holder. Preferably, the needle is heated to melt, soften, or otherwise weaken a material and/or adhesive connecting the needle with the needle holder. Preferably the heating is electrical heating, including completing an electrical circuit through the needle and passing current through the needle, and/or passing current through a heating element.
US10238810B2	Automatic injection device An automatic injection device including a housing element, at least one resilient element arranged to be located within the housing element, a syringe including at least one syringe piston, a needle guard adapted for selectable positioning with respect to the housing element and a selectable driving element adapted, when actuated, to be driven by the at least one resilient element for initially displacing the syringe relative to the housing element from a non-penetration position to a penetration position and thereafter displacing the at least one syringe piston in the syringe to effect drug delivery and displacing the needle guard into a needle guarding position.
US10238807B2	Drive mechanism and injection device herewith The present invention relates to a drive mechanism which is suitable for an injection device, especially a pen type drug delivery device. The mechanism includes a housing, a dosing member which during dose setting, dose resetting and dose dispensing rotates relative to the housing between a zero dose position and a maximum dose position, and an insert that is rotationally constrained to the housing. The dosing member and the insert each include at least one abutment feature contacting each other when the dosing member reaches its zero dose position during dose dispensing, and an audible and/or tactile feedback is generated by the contact of the abutment features.
US10238806B2	Medicament delivery devices for administration of a medicament within a prefilled syringe An apparatus includes a housing, a medicament container and a movable member. The medicament container is configured to move within the housing between a first position and a second position in response to a force produced by an energy storage member. A proximal end portion of the medicament container includes a flange and has a plunger disposed therein. A first shoulder of the movable member is configured to exert the force on the flange to move the medicament container from the first position to the second position. A portion of the first shoulder deforms when the medicament container is in the second position such that at least a portion of the force is exerted upon the plunger. A second shoulder of the movable member is configured to exert a retraction force on the flange to move the medicament container from the second position towards the first position.
US10238800B2	Electronic device and method of operating electronic device An electronic device and a method of operating the electronic device are provided. The method includes sensing a weight of an intravenous (IV) fluid injected into a user; measuring a time remaining until injection of the IV fluid is completed, based on the sensed weight of the IV fluid; determining whether the measured remaining time is equal to or less than a predetermined value; and transmitting an alarm signal indicating an injection state of the IV fluid to an external device based on a result of the determining.
US10238791B2	Flexible member for resisting retrograde flow The present disclosure is directed to a valve structure that comprises a flexible structure having a distal portion configured for attachment to a first member and a proximal portion configured for attachment to a second member. The flexible structure is configured such that when the first member is extended distally relative to the second member, the flexible structure adopts a reduced width profile and such that when the first member is retracted proximally relative to the second member to a point of maximal retraction, the flexible structure adopts an expanded width profile, which is more resistant to deformation due to fluid pressure in a proximal direction than it is to deformation due to fluid pressure in a distal direction. The present disclosure is also directed to devices and methods pertaining to such a valve structure.
US10238790B2	Syringe holder A syringe adapter for holding various sizes of syringes. A syringe includes a tip, a barrel, a plunger, a flange, and a syringe axis extending from the tip to the plunger. An example syringe holder attaches to a fluid delivery system and includes a syringe clamp. The syringe holder holds a syringe stationary in the syringe clamp. The syringe clamp is offset from the fluid delivery system such that the syringe, or connections to the syringe, does not interfere with other components of the fluid delivery system. The syringe holder may include a support bar, which the syringe clamp can slide along. Alternatively, the syringe clamp may be rotatable.
US10238788B2	Motorized irrigation system A portable irrigation system comprising a reservoir for an irrigating liquid, a probe for arrangement in a user, an electrical system, a control unit for controlling the transfer of irrigation liquid and tubing providing fluid communication between said reservoir, control unit and probe.
US10238786B2	Leukocyte filtration unit with reduced platelet adhesion A filtration unit to selectively remove leukocytes from fluids containing platelets and systems including a filtration unit are provided. In one embodiment, a filtration unit is provided including an outer casing enclosing a porous element which includes a leukocyte-removal medium with a coating. The coating includes a polymer containing a main hydrophobic chain and a hydrophilic poly(ethylene oxide) side chain and having a mass average molar mass in the range of from about 1,000 g/mol to about 20,000 g/mol. The hydrophilic poly(ethylene oxide) side chain includes from 9 to 50 ethylene oxide units, and the mass percentage of the poly(ethylene oxide) side chain is less than about 50% of the mass average molar mass of the polymer.
US10238785B2	Membrane and device for treating hemolytic events The present disclosure relates to a hemodialysis membrane for the treatment of hemolytic events, especially acute episodes of hemolysis which lead to elevated levels of plasma free hemoglobin. The present disclosure further relates to methods of removing hemoglobin from the blood of patients undergoing a hemolytic event. The treatment and method encompasses using a hemodialysis membrane which is characterized in that it comprises at least one hydrophobic polymer and at least one hydrophilic polymer and in that it has a MWRO of between 15 and 20 kD and a MWCO of between 170-320 kD, or, in the alternative, has a MWRO of between 9 and 14 kD and a MWCO of between 55 kD and 130 kD.
US10238781B2	Blood bag system and blood treatment method A blood bag system includes: a first bag in which blood containing multiple components is stored; a second bag in which a relative medium-density component is stored; a third bag in which a relative low-density component is stored; a first tube through which the relative low-density component and the relative medium-density component are transported from the first bag to the second bag; and a second tube through which the relative low-density component is transported from the first bag to the third bag. A blood treatment method involves: centrifuging blood containing multiple components in a first bag, transporting a low-density component from the first bag to a third bag through a first tube and transporting a relative medium-density component from the first bag to the second bag through the first tube.
US10238777B2	Hydrophobic porous non mechanical valve for medical suction device The present invention provides a porous non mechanical valve which retards or prevents the passage of bodily fluids and is resistant to being occluded or blocked by exposure to the surgical fumes or aerosols encountered during surgical procedures.
US10238774B2	Biological implant Provided is a biological implant which exhibits high binding ability to a biological tissue after having been embedded in a living organism, which secures an appropriate strength depending on a site to which the implant is applied, and in which a micropore structural portion is less likely to be removed from a macropore structural portion. The biological implant includes a macropore structural portion which defines macropores of the biological implant, and a micropore structural portion which has micropores therein, the micropores having a pore size smaller than that of the macropores, the biological implant being characterized in that the macropore structural portion has substantially no pores therein; the micropore structural portion is provided on the surface of the macropore structural portion; the macropore structural portion and the micropore structural portion are formed of the same engineering plastic material; and the macropore structural portion is formed of a single material.
US10238769B2	Graft for directed vascular and lymphatic regeneration and methods to guide endothelial cell assembly Embodiments of the present invention relate to a therapeutic device (graft) comprising a collagen membrane having an aligned uniaxial or biaxial structure such that mammalian cells plated on the membrane align mainly along the direction of the collagen fibrils. In a further aspect, a graft comprising a substantially tubular body, wherein the body has an exterior surface, an interior surface, and at least one lumen extending therethrough such that a fluid flow through the lumen can direct mammalian cell migration. In a further aspect, mammalian cells or growth and angiogenic factors can be optionally attached to the exterior and/or interior surface of the substantially tubular body. In various aspects, the graft can be used as a vascular prosthesis, a stent, or a nerve regeneration scaffold. Methods of preparing and implanting same are also provided.
US10238767B2	Mono-layer thin film adhesive compounds and methods of synthesis and use The invention relates provides synthetic medical adhesives which exploit plant derivatives to form covalent bonds with amines and thiols on tissue surfaces.
US10238762B2	Incorporating metals, metal oxides and compounds on the inner and outer surfaces of nanotubes and between the walls of the nanotubes and preparation thereof A multi-walled titanium-based nanotube array containing metal or non-metal dopants is formed, in which the dopants are in the form of ions, compounds, clusters and particles located on at least one of a surface, inter-wall space and core of the nanotube. The structure can include multiple dopants, in the form of metal or non-metal ions, compounds, clusters or particles. The dopants can be located on one or more of on the surface of the nanotube, the inter-wall space (interlayer) of the nanotube and the core of the nanotube. The nanotubes may be formed by providing a titanium precursor, converting the titanium precursor into titanium-based layered materials to form titanium-based nanosheets, and transforming the titanium-based nanosheets to multi-walled titanium-based nanotubes.
US10238758B2	Radiolabeled alpha-melanocyte stimulating hormone hybrid peptide for melanoma targeting The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue, suggesting favorable selective activity of compounds according to the present invention, which can be used as effective therapeutic agents against melanoma, including metastatic melanoma. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are useful to initiate therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic and therapeutic tools for a number of conditions and diseases states, especially melanoma.
US10238756B2	Lipid nanoparticles and uses thereof The present invention relates to lipid-associated indocyanine green particles for enhanced functional high-resolution near-infrared fluorescence medical imaging of lymphatic vessels, lymph nodes, lymphatic abnormalities, tumors, and inflammation.
US10238755B2	Methods and compositions for regulation of cell aging, carcinogenesis and reprogramming Compositions and methods described herein include somatic cells that are competent for reprogramming and malignant transformation and are characterized by a reduction of the levels of Sp100 in the cells, cells having markers of pluripotent stem cells, and methods for preparing same. Methods for reversably regulating aging or reprogramming to pluripotency in a somatic cell involve modulating the expression of Sp100 therein. Methods and compositions for retarding the growth of or suppressing unwanted cell proliferation involve expressing, inducing expression of, or upregulating, Sp100 in a targeted cell that is undergoing unrestricted proliferation or replication or increasing exposure to Sp100 in the environment or microenvironment of the targeted cell. Also disclosed are methods for treating a proliferative disease or condition by increasing expression or levels of Sp100 in the targeted cell or its environment.
US10238752B2	Single-stranded nucleic acid molecule for regulating expression of gene having delivering function The invention provides a single-stranded nucleic acid capable of inhibiting expression of a target gene having a delivery function. The nucleic acid contains, from the 5′-side to the 3′-side, a 5′-side region (Xc), a linker region (Lx), an inner region (Z), a linker region (Ly) and a 3′-side region (Yc) in this order, wherein the inner region (Z) is constituted by linkage of the inner 5′-side region (X) and the inner 3′-side region (Y), the 5′-side region (Xc) is complementary to the inner 5′-side region (X), the 3′-side region (Yc) is complementary to the inner 3′-side region (Y), at least one of the inner region (Z), the 5′-side region (Xc) and the 3′-side region (Yc) comprises an expression inhibitory sequence that inhibits expression of a target gene, and at least one of the 5′-terminus, the 3′-terminus, the linker region (Lx) and the linker region (Ly) is bound to a bio-related substance.
US10238751B2	Cytotoxic benzodiazepine derivatives The invention relates to novel benzodiazepine derivatives with antiproliferative activity and more specifically to novel benzodiazepine compounds of formula (I)-(VI). The invention also provides conjugates of the benzodiazepine compounds linked to a cell-binding agent. The invention further provides compositions and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the compounds or conjugates of the invention.
US10238749B2	Angiotensinogen (AGT) iRNA compositions and methods of use thereof The present invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the angiotensinogen (AGT) gene, and methods of using such RNAi agents to inhibit expression of AGT and methods of treating subjects having an AGT-associated disorder, e.g., hypertension.
US10238741B2	Nucleic acid constructs for presentation of CD4 and CD8 epitopes, cellular transfection and uses thereof The invention relates to constructs, cells and methods for modulating the immune system that optimize presentation of CD4 and CD8 epitopes to antigen-presenting cells and transfection into cells. Epitopes to either self antigens or non-self antigens can be used to optimize either a tolerance or immunogenicity to those epitopes, respectively. Certain new constructs encode one or more dominant, disease-driving epitopes (CD4) targeted for MHCII processing within the endosomes of a cell and one or more epitopes (CD8) targeted for MHCI processing within the cytosol of the cell, to produce the maximum antigen/epitope presentation in the immune system, and further include an MHCII activator sequence. Alternatively, the new constructs encode CD4 and CD8 epitopes operably linked to a secretion signal.
US10238737B2	Oral administration of at least one pharmaceutical and/or antigenic active substance Disclosed is a gastro-resistant vector for the oral administration of at least one pharmaceutical and/or antigenic active substance including an aqueous phase (W) and an oily phase (O) in the form of a water-in-oil (W/O)-type emulsion wherein the aqueous phase includes at least one active principle and between 2 and 40 wt. % of a hydrophilic polymer that is insoluble in an aqueous phase of pH<6.5.
US10238730B2	Cold-adapted-viral-attenuation (CAVA) and novel attenuated poliovirus strains A poliovirus (PV) strain was attenuated by a novel method of Cold-Adapted-Viral-Attenuation (CAVA). The resulting recombinant attenuated PV, CAVA-PV, shows wild-type replication at 30° C., but no substantial replication at 37° C. The inability to replicate at 37° C. is defined by an inability to quantify virus during infection at this temperature by titration (infectious units), qPCR (viral RNA) or Electron Microscopy (visual signs of infection). CAVA-PV is genetically stable under production conditions and shows utility for use as the backbone to produce attenuated strains with the same antigenic profile as conventional vaccines by replacing the sequence coding for the capsid of CAVA-PV with sequences coding for capsids of different PV strains. Furthermore, mutations identified in CAVA-PV can be engineered into different, even wild-type and neurovirulent poliovirus background strains to obtain additional CAVA-PV strains.
US10238728B2	Peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

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