Document Document Title
US10184435B2 Fuel injection unit for internal combustion engine
The present disclosure provides a fuel injection unit for an internal combustion engine. The fuel injection unit includes: a separator that is disposed in an intake port to supply air into a combustion chamber formed in an engine head, and that divides a channel for air into an upper channel and a lower channel; a blade disposed ahead of the separator and opening or closing the upper channel or the lower channel by rotating; and a first injector disposed over the intake port. In particular, when the first injector injects fuel, the blade does not interfere with the fuel.
US10184430B2 Diagnostic device for evaporated fuel processing device
A diagnosis device for an evaporated fuel processing device includes: a pump arranged to pressurize or depressurize a system including the fuel tank and the canister; at least one pressure sensor arranged to sense a pressure within the system; and a fuel temperature sensor arranged to sense a temperature of a fuel within the fuel tank, the diagnosis device being configured to select a first leakage diagnosis using a positive pressure or a negative pressure existing within the fuel tank, or a second leakage diagnosis using a forcible pressurization or a forcible depressurization by the pump, based on a temperature difference between a fuel temperature at a start of driving, and a fuel temperature after an end of the driving, with respect to a request of a leakage diagnosis.
US10184429B2 Methods and system for selecting a location for water injection in an engine
Methods and systems are provided for selecting a location for water injection during a water injection event based on engine operating conditions. In one example, a method may include selecting a location for water injection from each of an intake port of each cylinder, an intake manifold upstream of all engine cylinders, and directly into each cylinder based on engine operating conditions. Further, the method may include adjusting water injection at the selected location and engine operating parameters in response the evaporated and/or condensed portion of water.
US10184423B2 Two-stroke engine
A two-stroke engine is provided that has a cylinder, in which a combustion chamber is formed, and a piston, which delimits the combustion chamber and which drives a crankshaft rotatably mounted in a crankcase. The piston controls an inlet window for fuel/air mixture into the crankcase interior. A flow guide element is arranged in the crankcase interior which extends adjacent to the inlet window. The flow guide element has at least one first inflow surface by which at least a first partial quantity of the fuel/air mixture flowing in through the inlet window is diverted in the direction of the crankshaft.
US10184419B2 Cooling device for internal combustion engine
A cooling device for an internal combustion engine includes a HT cooling system, a LT cooling system, and an electronic control unit. The electronic control unit is configured to, if a HT temperature has reached a HT determination value, control an operation state of the HT cooling system to start cooling for maintaining the HT temperature at a HT target temperature. The electronic control unit is configured to, if a LT temperature being a temperature of a LT cooling medium has reached a LT determination value, start a LT cooling control for maintaining the LT temperature at a LT target temperature under a specific condition where an early warm-up of the internal combustion engine is not required. The electronic control unit is configured to start the LT cooling control if the HT temperature has reached the HT determination value under a condition where the early warm-up is required.
US10184414B2 System and method for evaluating vehicle fuel injection system
A method for analyzing a fuel injection system includes generating injection commands, including attenuating a predetermined fuel request schedule for a different one of the plurality of injectors in a plurality of test cycles. Fuel is injected according to the injection commands to complete the plurality of test cycles. The processor generates pump commands for the pump to maintain a substantially constant pressure of the common rail during the test cycles. First command data are stored for the plurality of test cycles corresponding to the injection commands sent during the test cycles. Second command data are stored for the test cycles corresponding to the pump commands sent during the test cycles. The processor processes the first command data and the second command data to determine flow characteristics of the plurality of fuel injectors.
US10184408B2 Device for changing a compression ratio of a cylinder unit of a reciprocating-piston internal combustion engine
A device for changing a compression ratio of a cylinder unit of a reciprocating piston internal combustion engine has an eccentric bushing which is rotatably arranged in a bore of a connecting rod eye. Said eye encloses a crank pin of a crankshaft, and the bushing is rotatably guided in the bore and can be locked via locking openings, which are arranged to be offset from each other by preferably approximately 180°. The connecting rod has a locking apparatus which interacts optionally with the locking openings and via which the eccentric bushing can only ever be transferred from one position to the next. The locking apparatus has a sliding guideway extending parallel to the longitudinal axis of the bore of the connecting rod bearing eye. The sliding guide interacts with actuating pins arranged in the locking openings and can be displaced radially with respect to the bushing.
US10184405B1 Aircraft engine icing event avoidance and mitigation through real-time simulation and controls
A process for mitigating or proactively avoiding an aircraft engine icing event may include detecting ice crystals in the atmosphere using one or more sensors on board an aircraft in real time. The process may also include modulating one or more engine operating conditions to proactively change an ice accretion location, to avoid the occurrence of an icing event. The process may further include implementing one or more modulated engine operating conditions in engine controls software, hardware, or both.
US10184404B2 Geared gas turbine engine accessory gearbox
A gas turbine engine includes a gearbox. The gearbox includes a housing at a forward part of a core compartment of a gas turbine engine. A plurality of accessory drives are each configured to rotatably couple the gas turbine engine accessory gearbox to one of a plurality of accessory components.
US10184402B2 Ceramic matrix composite turbine exhaust case for a gas turbine engine
A gas turbine engine according to an example of the present disclosure includes, among other things, a turbine case extending along a turbine axis and a CMC turbine exhaust case mounted to the turbine case. The CMC turbine exhaust case includes a CMC core nacelle aft portion, a CMC tail cone connected to the CMC core nacelle aft portion, and a multiple of CMC turbine exhaust case struts extending between the CMC core nacelle aft portion and the CMC tail cone. The CMC core nacelle aft portion, the CMC tail cone and the turbine case are arranged along the turbine axis. The CMC turbine exhaust case is mounted to the turbine case at a flange such that the CMC tail cone is axially spaced apart from the turbine case relative to the turbine axis.
US10184398B2 Acoustic structural panel with slanted core
A nacelle may comprise a noise suppressing structure. The noise suppressing structure may comprise a plurality of noise suppressing cells situated between a perforated layer of material and a non-perforated layer of material. The plurality of noise suppressing cells may contact the perforated layer of material and the non-perforated layer of material at an acute angle (e.g., between twenty and seventy-five degrees) such that the plurality of noise suppressing cells are non-orthogonal to the perforated layer of material and the non-perforated layer of material. Further, each of the plurality of noise suppressing cells may comprise a hexagonal cross-sectional profile. Further still, the noise suppressing structure may comprise a support structure comprising a plurality of support members, wherein the plurality of noise suppressing cells are situated within the support structure.
US10184394B2 Variable compression ratio engine
According to the present invention a variable compression ratio engine having a pair of eccentric control shafts, a crankcase and a cylinder jug has contiguous metal casting bearing sockets located in the crankcase for supporting the eccentric control shaft, and an eccentric control shaft axis location close in to the working cylinders, and located between the bottom edge of the working cylinders and the floor of the water jacket, thereby providing a rigid and compact crankcase and cylinder jug assembly. Nesting of the eccentric control shafts under the water jacket and close in to the cylinder bores, and also eliminating use of removable bearing caps in the crankcase provides a compact and rigid crankcase and cylinder jug assembly. Side walls that extend above and below the eccentric control shafts provide added rigidity and also enclose the crankcase for containing oil within the crankcase. Internal webbing within the crankcase provides added rigidity and provides an aerodynamic crankcase interior and an oil drain back passageway for reduced internal aerodynamic drag on the cranktrain at high engine speeds. A major benefit of the present invention is that it is robust and can support the large forces encountered in internal combustion engines. Another benefit of the present invention is that removable bearing caps are not required, resulting in a lower cost and a smaller size than prior art engines having removable bearing caps.
US10184393B2 Engine generator
An engine generator has an opening and closing mechanism including: a control shaft provided to a valve shaft of a choke valve to be rotatable relative thereto within a predetermined angular range; an urging member urging the valve shaft relative to the control shaft in a direction in which an opening degree of the choke valve decreases; a restriction mechanism that sets a minimum opening degree of the choke valve by restricting a range of rotation of the control shaft; a choke operating portion which, upon operation, drives the restriction mechanism in a direction in which the minimum opening degree of the choke valve decreases; and a negative pressure mechanism driven by a negative pressure generated during an operation of the engine to cause the control shaft to rotate to increase the minimum opening degree of the choke valve within the range of rotation restricted by the restriction mechanism.
US10184391B2 Internal combustion engine and a method for controlling such an internal combustion engine
The disclosure relates to a method for operating an internal combustion engine in a six-stroke mode, wherein the engine comprises at least one cylinder with a reciprocating piston, each cylinder having at least one inlet and outlet valve. The method involves performing a first stroke where a gas comprising at least air is induced into a combustion chamber from an intake conduit; a second stroke where the gas and injected fuel is compressed; a third stroke where the compressed fuel/gas mixture is expanded following an ignition; a fourth stroke where combusted exhaust gas is expelled through a catalyst body into a first exhaust conduit; a fifth stroke where pressurized fuel and pressurized heated water is injected into the combustion chamber to be expanded; and a sixth stroke where steam and gaseous fuel mixture is expelled through the catalyst body into a second exhaust conduit.
US10184383B2 Visual marking and geometric poka-yoke for fluid and electrical lines of aftertreatment systems
An aftertreatment system comprises an SCR system and at least one reductant insertion assembly fluidly coupled thereto. The reductant insertion assembly includes an injector and reductant storage tank. The injector includes a first fluid connector and a second fluid connector. A first fluid connector marking is defined on the first fluid connector and a second fluid connector marking is defined on the second fluid connector. The reductant storage tank includes a first fluid conduit fluidly coupled to the first fluid connector and a second fluid conduit fluidly coupled to the second fluid connector. A first fluid conduit marking is defined on the first fluid conduit, and a second fluid conduit marking is defined on the second fluid conduit. The first fluid conduit marking corresponds to the first fluid connector marking, and the second fluid conduit marking corresponds to the second fluid connector marking, thereby identifying a coupling relationship therebetween.
US10184379B2 Exhaust purification system for internal combustion engine
A particulate filter for trapping the particulate matter which is contained in the exhaust gas is provided inside an engine exhaust passage. Additional fuel is secondarily injected from a fuel injector in an engine expansion stroke or exhaust stroke or hydrocarbons are secondarily added from an addition valve which is provided upstream of the particulate filter in the exhaust pipe. An amount of hydrocarbons which come from the fuel injector or addition valve and then adhere in the form of a liquid to the inflow end of the particulate filter, and an amount of particulate matter which reaches the inflow end of the particulate filter are respectively estimated. A degree of clogging at the inflow end of the particulate filter is estimated based on the amount of hydrocarbons and the amount of particulate matter.
US10184378B2 Exhaust gas purification system and method for a work vehicle
A work vehicle includes an engine, a battery, an exhaust gas purification system or device, and a notification device. The exhaust gas purification system or device is capable of performing a purification process purifying exhaust gas of the engine, and operates with electric power from the battery and performs an end process. The notification device provides notification that the exhaust gas purification system or device is performing the end process or that the end process is completed.
US10184375B2 Engine device
The engine device has a first case which removes particulate matters in exhaust gas of the engine, and a second case which removes nitrogen oxides in the exhaust gas of the engine. The second case is connected to the first case via a urea mixing pipe. The engine device is provided with a plurality of support leg bodies which are connected their one end sides to the engine, and a support base which is connected to a plurality of support leg bodies. The first case and the second case are arranged in the support base.
US10184374B2 Apparatus and method for desulfation of a catalyst used in a lean burn methane source fueled combustion system
Apparatus for reactivating a sulfur poisoned oxidation catalyst operating in exhaust of a lean burn, methane source fueled combustion device. Reactivation includes desulfation of the poisoned catalyst through a CO supplementation apparatus communicating with the control unit that is adapted to supplement CO content in exhaust reaching the catalyst, while avoiding an overall rich exhaust atmosphere at the catalyst (e.g., an added supply of hydrocarbons to one or more-of the lean burn engine's combustion chambers as by an ECU controlled extra supply of NG to some of the combustion chambers). Also featured is a method for desulfation of an oxidation catalyst of a lean burn CNG engine by supplying excess CO to exhaust reaching the catalyst while retaining an overall lean state, and a method of assembling an apparatus for reactivating a sulfur deactivated lean burn NG engine catalyst by assembling a CO supplementation apparatus with control unit.
US10184366B2 Valve actuating device
A valve actuating device for variable valve control wherein at least one articulation point between a valve lever and a gas exchange valve, or a force transmission element which acts on the gas exchange valve, is adjustable by way of an adjusting device which includes a piston displaceably mounted in the valve lever, a piston rod which is connected to the piston is connected in an articulated manner at a first articulation point to a first end of a push rod whose second end is connected in an articulated manner at a second articulation point to the gas exchange valve, or the force transmission part which acts on the gas exchange valve, the first articulation point being displaced in the longitudinal direction of the piston rod at least between a first position and a second position.
US10184359B2 Waste heat recovery device and waste heat recovery method
A waste heat recovery device including: a heater which evaporates an working medium by exchanging heat between supercharging air supplied to an engine and the working medium; a heat exchanger which heats the working medium by exchanging heat between the working medium which has flowed out from the heater and a heating medium; and an expander into which the working medium which has flowed out from the heat exchanger flows; a motive power recovery device; a condenser which condenses the working medium; and a pump which sends the working medium to a heater.
US10184353B2 Blade outer air seal cooling scheme
A cooling scheme for a blade outer air seal includes a perimeter cooling arrangement configured to convectively cool a perimeter of the blade outer air seal, and a core cooling arrangement configured to cool a central portion of the blade outer air seal through impingement cooling and to provide film cooling to an inner diameter face of the blade outer air seal.
US10184352B2 Turbine shroud segment with integrated cooling air distribution system
A turbine shroud adapted for use in a gas turbine engine includes a plurality of metallic carrier segments and a plurality of blade track segments mounted to corresponding metallic carrier segments. Cooling air is directed onto the blade track segments to cool the blade track segments when exposed to high temperatures in a gas turbine engine.
US10184349B2 Apparatus having a vacuum chamber configured to convert electromagnetic waves to electricity for driving a steam generator system
An electricity generator includes a core having a pair of opposing end caps interconnected by a mid-section cooperating to define an interior chamber. In use, the core is held at a vacuum and filled with at least one inert gas. A frequency generator is attached for introducing and inputting electromagnetic waves into the interior chamber. A waveguide tube is provided to connect the frequency generator to the core, allowing for the passage of electromagnetic waves from the frequency generator into the interior chamber. In addition, a plurality of electrodes is provided which extend into the interior chamber to heat the inert gas and conduct the flow of electricity away from a lining on the interior chamber in order to produce steam. The electricity generator further includes at least one external steam generator system for converting the produced steam into energy.
US10184344B2 Additively manufactured connection for a turbine nozzle
Turbine nozzles are provided for gas turbine engines. The turbine nozzle includes an arcuate inner band; an arcuate outer band; and a nozzle vane disposed between the arcuate inner band and the arcuate outer band. The radially inner end of the nozzle vane is attached to the arcuate inner band through an interlocking transition zone including a plurality of projections alternately extending from the radially inner end of the nozzle vane and the arcuate inner band, respectively, to undetachably couple the nozzle vane and the arcuate inner band. Optionally, the radially outer end of each nozzle vane is also attached to the arcuate outer band through an interlocking transition zone.
US10184342B2 System for cooling seal rails of tip shroud of turbine blade
A turbine blade includes a tip shroud having a seal rail. The seal rail includes a tangential surface extending between tangential ends. The turbine blade includes a root portion configured to couple to a rotor and an airfoil portion extending between the root portion and the tip shroud. The seal rail includes a cooling passage extending along a length of the seal rail. The cooling passage is fluidly coupled to a cooling plenum to receive a cooling fluid via an intermediate cooling passage extending between the cooling passage and a cooling plenum. The seal rail includes cooling outlet passages fluidly coupled to the cooling passage. The cooling outlet passages are disposed within the seal rail and extend between the cooling passage and the tangential surface of the seal rail. The cooling outlet passages are configured to discharge the cooling fluid from the tip shroud via the tangential surface.
US10184332B2 Well tools with vibratory telemetry to optical line therein
A well tool can include an outer housing and a vibratory transmitter disposed in the outer housing. The vibratory transmitter transmits a vibratory signal to an optical line disposed in the outer housing. A well system can include an optical line extending in a wellbore, and at least one well tool secured to the optical line and including a vibratory transmitter which transmits a vibratory signal to the optical line. The optical line conveys the well tool into the wellbore. A method of telemetering data from a well tool to an optical line can include securing the well tool to the optical line without optically connecting the well tool to the optical line, and conveying the well tool in a wellbore on the optical line.
US10184331B2 Explosive assembly and method
An explosive assembly includes a first explosive unit having a first longitudinal end portion having a first mechanical coupling feature, a second explosive unit having a second longitudinal end portion having a second mechanical coupling feature, and a tubular connector having a first end portion mechanically coupled to the first mechanical coupling feature and a second end portion mechanically coupled to the second mechanical coupling feature, such that the first explosive unit, the connector, and the second explosive unit are connected together end-to-end along a common longitudinal axis. Each explosive unit can contain a high explosive material and a detonator, and the connector can comprise a detonation control module electrically coupled to the detonators and configured to detonate the explosive units.
US10184330B2 Antenna operation for reservoir heating
Systems and methods are provided for maintaining the performance and operational stability of an RF (radio frequency) antenna that is positioned in a hydrocarbon-bearing formation, for heating the formation using electromagnetic energy in the radio frequency range. Contaminants such as water or brine, metallic particulates and ionic or organic materials frequently occur in a wellbore being prepared for RF heating, or in an RF antenna installed in the wellbore. Prior to applying RF electrical energy to the formation, the antenna is decontaminated by circulating a preconditioning fluid through the antenna and recovering a spent fluid for treating and recycle. Decontamination is continued while the spent fluid from the antenna includes, but not limited to, water, metallic particles, ionic species, organic compounds contaminants, etc. An operational power level of radio frequency electrical energy is then applied to the decontaminated antenna for providing thermal energy to the hydrocarbon-bearing formation.
US10184329B2 Microemulsions, mesophase surfactant and micellar solutions, and in situ-formed fluids formulated with high density brine
Mesophase surfactant solutions and/or micellar solutions, pre-formed single phase microemulsions (SPMEs), and in situ-formed fluids may be used to clean up and remove hydrocarbons and synthetic oils such as oil-based mud filter cake and near wellbore damage in oil and gas wells. Removal occurs by solubilization of the hydrocarbons and synthetic oils into the micellar solutions, SPME, in situ-formed fluids, etc. when the fluid formulation contacts the hydrocarbons and synthetic oils. An in situ-formed fluid (e.g. microemulsion), may be formed when one or more surfactant, an optional linker, optional co-surfactant, optional acid, optional co-solvent and a polar high-density brine phase, and eventually some amount of organic phase, contacts the subterranean location and solubilizes the hydrocarbons and synthetic oils encountered, such as in the near wellbore of a subterranean formation. The micellar solutions, microemulsions, in situ-formed fluids, etc. are effective for removing the formation damage caused by hydrocarbons and synthetic oils.
US10184328B1 Sand diverting valve rod guide
The present invention provides a valve rod guide which acts as a sand diverter for pushing or expelling sand to the outside of the pump, thereby reducing sand that otherwise have settled in a down-hole pump.
US10184323B2 Base pipes for sand control screen assemblies
A sand control screen assembly includes a base pipe having openings having non-uniform cross-section. The sand control screen assembly can also include a drainage layer positioned about the base pipe, a filter medium, and a protective shroud. The sand control screen assembly prevents the flow of particulate material of a predetermined size therethrough and allows the flow of production fluids therethrough.
US10184322B2 System, method and apparatus for creating an electrical glow discharge
The present invention provides system, method and apparatus for creating an electric glow discharge that includes a first and second electrically conductive screens having substantially equidistant a gap between them, one or more insulators attached to the electrically conductive screens, and a non-conductive granular material disposed within the gap. The electric glow discharge is created whenever: (a) the first electrically conductive screen is connected to an electrical power source such that it is a cathode, the second electrically conductive screen is connected to the electrical power supply such that it is an anode, and the electrically conductive fluid is introduced into the gap, or (b) both electrically conductive screens are connected to the electrical power supply such they are the cathode, and the electrically conductive fluid is introduced between both electrically conductive screens and an external anode connected to the electrical power supply.
US10184320B2 Systems, methods, and computer medium to enhance hydrocarbon reservoir simulation
Embodiments of systems, non-transitory computer-readable medium having one or more computer programs stored therein, and computer-implemented methods are provided to enhance hydrocarbon reservoir simulation for a plurality of hydrocarbon reservoirs. According to embodiments, a plurality of fluid flow simulation runs in each of a plurality of hydrocarbon reservoirs are initiated. Then, each of a first set of one or more of the plurality of simulation runs are terminated while each of a second set of one or more of the plurality of simulation runs continue. Terminating each of the first set of simulation runs can increase processing availability within a collective limited and predetermined combined computing capacity of one or more processors to another one or more of the plurality of simulation runs being run. Consequently, terminating each of the first set of simulation runs can thereby reduce total hydrocarbon reservoir simulation run time.
US10184318B2 Downhole communication valve and method of use
A downhole communication valve containing a piston and chamber which allows hyrdrostatic testing of a casing or tubing string multiple times before permanently opening communication ports to the exterior.
US10184317B2 Check valve with valve member biased by connectors extending from a valve seat for operation of a subterranean tool
A check valve has a valve member flexibly attached to a seat with resilient members that fold in response to flow above a predetermined value to shut the valve. The flexibly extending members store potential energy that is released to separate the valve member from the seat when the pressure applied against the seated valve member declines to the point that the potential energy stored in the flexible members is able to move the valve member off the seat. The valve assembly including the valve member, the seat and the flexible members can be a common material, or can be all one or more nonmetallic materials or involve composites or other easily drilled materials that are compatible with the operating conditions of pressure differential, temperature and composition of the well fluid. The check valve assembly can be pushed with pressure when closed to operate a subterranean tool.
US10184316B2 Three position interventionless treatment and production valve assembly
A first sleeve is shifted with a ball landed on a seat to open treating ports. At the conclusion of the treating such as fracturing, another ball is dropped on a seat in an adjacent sleeve. The adjacent sleeve shifts to contact the initial sleeve that was shifted earlier. When the sleeves abut the treating ports are closed by the second sleeve and the production ports that are preferably screened are also opened by the shifting of the second sleeve against the first sleeve. The first sleeve hits a travel stop in the housing to produce the full open position for the treating ports. The balls can be progressively larger in a bottom up direction for the procedure or the balls can all be the same size as the landing of a ball on the first sleeve reconfigures the sleeve above for the same sized ball.
US10184312B2 Subsea tree and methods of using the same
A subsea tree for use with a well includes a master block that has a flow hub located at the top of the subsea tree, a flow bore in fluid communication with the well, a swab valve, and a master valve. A choke block is coupled to a side of the subsea tree and includes a choke in a flow passage of the choke block. The swab valve is selectively closed so that fluid flowing through the master block is directed through the choke in the choke block. A method for operating the subsea tree, includes directing flow of a first fluid into the flow bore of the subsea tree, through the choke of the choke block, and then into the flow bore of the subsea tree. The method includes reversing flow of a direction of a second fluid through the subsea tree.
US10184310B2 Flow control module
A system includes a flow-through component fluidly coupled to a wellhead and including an annular passage disposed about a central flow-through bore. The annular passage is transverse to the central flow-through bore. The central flow-through bore is downstream of the annular passage. The system also includes a first 90-degree elbow fluidly coupled to the flow-through component, a multi-phase flow meter disposed downstream of, and fluidly coupled to the first 90-degree elbow, a second 90-degree elbow disposed downstream of, and fluidly coupled to, the multi-phase flow meter, a monitor fluidly coupled to the second 90-degree elbow, and a choke disposed downstream of, and fluidly coupled to, the second 90-degree elbow, wherein, the central flow-through bore is downstream of the choke.
US10184308B2 Method and apparatus for downhole tool actuation
A downhole tool and a method for operating the downhole tool, in which the downhole tool includes a first sensing member, and a second sensing member. The first and second sensing members have a first communication status when the downhole tool is in a first configuration. The first and second sensing members have a second communication status that is different from the first communication status when the downhole tool is in a second configuration. The downhole tool is prevented from actuating prior to the first and second sensing members having the second communication status, and the downhole tool is permitted to actuate after the first and second members have the second communication status.
US10184304B2 Attachment for making up or breaking out pipe
An attachment is described that is configured for attachment to an arm of a piece of heavy construction equipment. The attachment is configured to rotate a section of pipe during break out (i.e. disconnection or disassembly) from another section of pipe and/or make up (i.e. connection or assembly) with another section of pipe. The attachment is configured to break the joint or torque the joint to a predetermined torque value, unthread or thread pipe, and lift the pipe under the power of the heavy construction equipment.
US10184296B2 Drilling system with flow control valve
A technique facilitates drilling of wellbores with a steerable system having a plurality of pads which may be selectively actuated in a lateral direction to apply a side force. Application of the side force is used to steer a drill bit. A valve system is positioned to control delivery of actuating fluid under pressure to individual pads in a manner that enables steering of the drill bit. The valve system allows drilling along a desired curve by controlling the flow of actuating fluid under pressure to specific steering pads at specific angular positions. The valve system also allows drilling along a desired trajectory by preventing exposure of the pads to the pressurized actuating fluid.
US10184294B2 Rock drilling machine and use thereof for hindering occurrence and spreading of cavitation bubbles
Rock drilling machine (10) comprising a piston that is arranged to move back and forth in a chamber (12a, 12b) when the rock drilling machine (10) is in use, a cavitation-sensitive component (14), and an oil channel that is arranged to extend between the chamber (12a, 12b) and said cavitation-sensitive component (14). The oil channel comprises a series of restrictions (18) and oil volumes (20) to hinder the movement of cavitation bubbles through said oil channel.
US10184291B2 Door for closing a chamber opening in a chamber wall of a vacuum chamber
A door for closing a chamber opening in a chamber wall of a vacuum chamber in relation to a surrounding space, in which the vacuum chamber is located, includes a door housing arranged, a closing member arranged in the surrounding space, and a rod, to which the closing member is connected. A first movement of the rod, through which the closing member is displaced from an open position into an intermediate position, occurs as a displacement of the rod in a longitudinal axis direction, and a second movement of the rod subsequent thereto is a displacement at an angle to the longitudinal axis or a pivoting about a pivot axis which is perpendicular to the longitudinal axis from the intermediate position into a closed position. The rod is moveably mounted via the bearing elements, that are arranged in an inner space of the door housing that is sealed with respect to the surrounding space or is connected to the surrounding space via a passage, with a filter, extending through a housing wall of the door housing. The rod is guided out of the inner space in a sealed manner.
US10184287B2 System and method for automated motor actuation in response to a travel-limit displacement of a movable barrier
The present invention is generally a system and method for automatically actuating or controlling a movable barrier in response to a travel-limit displacement of the movable barrier, and more specifically, a movable barrier operator system configured to respond automatically to a travel-limit displacement, or change in position of a barrier's travel limit, in order to return the movable barrier to its intended position. In an exemplary embodiment, an operator may receive from one or more sensors adapted to detect any change in the travel limit position, a signal detecting a change in barrier position. In response to this signal, the operator may generate a command in order to counter-act, or push-back, the undesired movement of the barrier. In some applications, the invention provides a measure of security. In other applications, the invention provides a measure of efficiency and overall stability of a movable barrier system.
US10184280B2 Automotive door hinge
A vehicle door hinge that includes a door bracket mountable to a vehicle door, a body bracket mountable to a vehicle body, a pivot bushing having a cylindrical bearing that is disposed within a pivot axis hole of the body bracket, and a pivot pin that rotatably couples the door bracket and the body bracket together. The pivot pin includes a first shoulder disposed within the cylindrical bearing; and the pivot pin includes a second shoulder extending from the first shoulder. The second shoulder has a knurled cylindrical surface that is disposed within a pivot axis hole of the door bracket.
US10184275B2 Butterfly handle locking device
A butterfly handle locking device that fits into the standard butterfly handle such as found on sportsboards, sportscraft and other objects, the locking device having two main body portions that fit together, each body portion having an extending flange and a central region with an axial bore extending therethrough, the two main body portions each having a wing arm extending from the central region, the two main body portions coupled together with an axle that passes through the axial bore of each.
US10184259B2 Underwater cleaner
The invention relates to an underwater cleaner (1), especially for a swimming pool, comprising a housing (2) in which an especially battery-powered pump having an electric motor (4) and an impeller (3) is arranged, wherein the housing (2) comprises an inlet opening (23) and an outlet opening (22) for a flow path, said flow path forming a first channel section (13) originating from the first inlet opening (23) and a second channel section (14) accommodating the impeller (3), wherein the second channel section (14) is arranged in an inclined manner in relation to the first channel section (13), and wherein the impeller axis (18) is arranged in an inclined manner in relation to a normal (24) to the opening cross-section of the inlet opening (23). The ratio A/B of a first cross-sectional surface A to a second cross-sectional surface B is less than 2.8, wherein the first cross-sectional surface A is defined by the smallest flow cross-section in the first channel section (13) and the second cross-sectional surface B by the smallest flow cross-section of the second channel section (14) directly at the pump inlet.In order to obtain the simplest possible underwater cleaner (1) with the lowest production costs, which offers high suction power with low flow losses even in the case of impellers (3) of relatively large diameters, the first channel section (13) converges continuously into the second channel section (14).
US10184256B2 Collapsible safety barrier and support post
A collapsible safety barrier and support post for releasably securing between a ceiling structure and a floor structure. The safety barrier and support post comprises a plurality of longitudinal rails hingedly secured to a first end post and to a second end post, an extension rail releasably engageable with the second end post, and a latching mechanism to releasably secure the extension rail to the second end post. The safety barrier has a deployed position and a collapsed position. When in its deployed position the barrier is secured between a floor and a ceiling structure. When in its collapsed position the longitudinal rails, the first and second end posts, and the extension rail are positioned generally parallel and adjacent to one another.
US10184250B1 Load bearing metal stud
An elongated load bearing metal stud including a web and a pair of flanges disposed on opposite sides of the stud. Formed in the central portion of the web is a channel. The channel includes a pair of diagonal sides and a section extending between the sides. The channel effectively divides the web and forms on each side of the channel an outer web surface that extends adjacent the channel the length of the stud. Each flange extends from the web and includes a side, back and a turned end that includes a terminal end and wherein the turned end extends generally parallel with the side of the flange.
US10184249B2 Expanding panel and method of manufacture
An expandable panel, constructed such that the expandable panel can at least expand in at least one direction, includes a panel having a front face and rear face bordered by side edges, end edges and a thickness dimension extending between the front and rear faces and includes discretely spaced cuts extending from the front face to the rear face or rear to front face. The cuts form bridging members between living hinges and are elongate and extend in a spaced longitudinal manner including at least one cut forming a side of the expandable panel located on one side of the cut, and at least two cuts located on a side of the expandable panel. The at least one cut on side and the other cuts on side together forming at least one pair of lines being substantially parallel, offset mirror images of each other and being intermeshed but not touching.
US10184245B2 Earthquake-resistant light tower with the tuned mass damper
The present invention relates to an earthquake-resistant light tower with a tuned mass damper, in which a tuned mass damper is installed in a head part of a light apparatus installed on the top of a tower to absorb an earthquake or other vibration, thereby protecting a tower from vibration.
US10184244B2 Shear link including replaceable cover plates
The present invention relates to a shear link including replaceable cover plates. The shear link includes first and second combination plates combined with a structure, a main frame that includes both ends fixed to the first and second combination plates respectively and a hollow formed in a center to pass therethrough forward and backward, first and second cover plates positioned to come into contact with left and right sides of the main frame respectively to cover the hollow and including a plurality of through holes passing therethrough forward and backward, and a combination unit that separably combines the main frame with the first and second cover plates.In the shear link including replaceable cover plates according to the present invention, since the first and second cover plates are separably combined with the main frame by the combination unit, the first and second cover plates deformed by an external force may be easily separated from the main frame to reduce time and costs consumed for a replacement operation.
US10184240B2 Tank and method for constructing dike
In an LNG tank, a dike is formed by arranging precast blocks in the circumferential direction and layering the precast blocks in the vertical direction. Each of the precast blocks has loop joints on the top, bottom, left, and right side faces, and concrete is deposited between each two precast blocks adjacent in the circumferential direction and the vertical direction, whereby masonry joints are formed in the vertical direction and the circumferential direction. Prestress is imparted to the dike by PC steel members. The PC steel members are provided in the circumferential direction and the vertical direction of the dike, and are arranged so as to avoid the masonry joints in the circumferential direction and the vertical direction. Therefore, it is possible to construct the dike in a short time, and it is possible to provide a tank or the like that can reduce the construction period.
US10184239B2 Covering consisting of a plurality of gratings inserted one into another
Covers for drains, manholes or similar constructions are known which comprise a first grate (10) made of sheet metal and comprising slots (11) and struts (12), said struts having top faces (13) and each strut having side faces (14, 14′) made of sheet metal bent with respect to the top face. In order to increase the rigidity it is proposed that at least a second grate (20) is provided, the struts (22) of which are inserted in the slots (11) of the first grate (10).
US10184238B2 Floor drain assembly and method
The present invention relates to an assembly for providing a drain in a floor. The drain assembly includes a drain conduit, a strainer and an adaptor. The drain conduit has an inner, surface that defines a fluid flow path, and an outer surface. The strainer is disposed above the drain conduit and has openings in fluid communication with the fluid flow path of the drain conduit. The adaptor may be securable in the drain conduit and may be connected to the strainer. Prior to securing the adaptor in the drain conduit, a position of the adaptor in the drain conduit may be moveable to allow a top surface of the strainer to be substantially aligned with the floor. A method of assembly is also disclosed.
US10184235B2 Directional fluid inlet
A fluid inlet portion for a waterless urinal cartridge is presented. The fluid inlet portion comprises to fluid director comprising a non-linear surface proximate a throat portion of the cartridge formed to impart a horizontal velocity component to fluid flowing through the throat portion of the cartridge to reduce vertical turbulence within the fluid. The fluid director can be formed so that it is in fluid communication with at least part of a fluid layer within the cartridge. The non-linear surface imparts a horizontal velocity component, thereby reducing disruption of the fluid layer by fluid flowing through the throat portion of the cartridge. The fluid director may be positioned within the cartridge to impart a substantially horizontal swirling motion to fluid within the cartridge. A fluid deflector proximate the fluid director can receive fluid from the fluid deflector and for re-directing the fluid from the fluid director.
US10184231B2 Pull-out faucet hose retraction system and method
A hose retraction system for a pull-out or pull-down faucet includes a support bracket configured to couple to a shank, a cylindrical housing mountable to the support bracket, and at least one constant force coil spring disposable in the cylindrical housing and configured to at least partially couple to a hose disposed in a faucet spout. The coil spring provides a recoil force sufficient to retract the hose when the hose is extended from the spout.
US10184230B2 Mechanical touch faucet
An inventive touch faucet device for coupling to a pressurized fluid supply is provided that includes a faucet with a depressible touch surface segment and an outlet, where a mechanical touch mechanism is actuated by the touch surface, and induces a fluid flow from the pressurized fluid supply through the outlet in response to a user depression of the touch surface segment. The touch faucet device may further include a mixing valve for control of fluid temperature and flow rate. The mechanical touch mechanism in embodiments of the inventive touch faucet device includes an activation knob in an activator mechanism that is actuated by pressure applied by the touch surface, and a hydraulic valve in mechanical communication with the activator mechanism, the activator mechanism controlling the hydraulic valve.
US10184227B2 Work machine
A work machine includes a machine body, an engine, a rotary electrical device, and a battery. The engine is provided on the machine body to move the machine body. The rotary electrical device is provided on the machine body to move the machine body and to generate electric power. The battery is to be charged by the rotary electrical device and to discharge electric power to the rotary electrical device to move the machine body. The battery being is provided adjacent to the engine.
US10184220B1 Boat fender holder
This disclosure to boat fender holders for improving the protection of boats and docks against damage. Disclosed herein are boat fender holders comprising a holder portion and a lip portion, whereby the lip portion defines one or more holes that are configured to receive one or more fasteners.
US10184212B2 Coupling body using Z-pin
Coupling body devices, including methods of making the same, are provided and described. A method of manufacturing a coupling body, for example, can include forming a tube by braiding nonmetal fibers, forming a flange by rolling inwards an end of the tube, providing a metallic connector, inserting at least one Z-pin in an end portion of the connector, and coupling the tube and the connector by inserting the Z-pin in the flange and performing a composite material forming process.
US10184209B2 Clothing treatment apparatus
A clothing treatment apparatus capable of enabling an orientation of a bag body and an orientation of an ozone supply apparatus to keep a desired relationship is provided. A clothing deodorizing apparatus comprises a bag body for accommodating clothing; an ozone supply apparatus for supplying air into the bag body; an introduction pipe for guiding the air with the ozone exhausted from the ozone supply apparatus into the bag body; a cylindrical part formed on the bag body and fixed with one end part of the introduction pipe; and an inserting port part formed on the ozone supply apparatus and configured to detachably install the other end part of the introduction pipe in a specified orientation.
US10184206B2 Clothes treating apparatus and control method thereof
Provided is a clothes treating apparatus which may include a cabinet defining an outer appearance of the apparatus and having an introduction opening, a clothes receiving device provided in the cabinet and receiving therein clothes through the introduction opening, a circulation passage through which internal air of the clothes receiving device circulates, a heat-exchanging passage connected to the circulation passage to guide external air outside the circulation passage into the circulation passage for heat exchange with the internal air of the circulation passage, and a fan provided at the heat-exchanging passage to generate airflow in the heat-exchanging passage.
US10184205B2 Laundry dryer with drainable motor shaft seat
A laundry dryer (2) includes a rotatable drum (6); a drying air fan for blowing air into the drum (6); and an electric motor (10) configured for rotating the drum (6) and/or the drying air fan. A shaft (30) of the electric motor (10) extends towards the drying air fan and/or a drum transmission system. A seat (80) which is at least partially concavely formed is positioned at least partially below the motor shaft (30). A draining device (82) is provided which is configured to allow liquid entering the seat (80) to be drained off.
US10184202B2 Washing machine, method for controlling washing machine, and computer readable recording medium
A washing machine, a method and computer readable recording medium. The washing machine includes a washing spindle and a spin-drying spindle, a coupling that is movable to be engaged with a rotation preventing unit of the washing machine so that power of the driving motor is transferred to the washing spindle but not to the spin-drying spindle, and is movable to a position in which the coupling is not engaged with the rotation preventing unit so that power of the driving motor is transferred to both the washing spindle and the spin-drying spindle, and a control device configured to, in a washing mode of the washing machine, bring the coupling into contact with the rotation preventing unit, cause the coupling to rotate in first and second directions so that the coupling is engaged with the rotation preventing unit, and determine an engagement state by test-operating the driving motor.
US10184201B2 Balancer and washing machine including the same
The present invention relates to a washing machine which includes a cylindrical part having a cylindrical shape and at least one balancer installed in the cylindrical part. The balancer includes a first balancer housing provided with a race in an annular shape with an open top and a second balancer housing to be coupled with the first balancer housing to cover the open top of the race. The balancer is installed in the cylindrical part in such a way that a coupling portion of the first balancer housing and the second balancer housing corresponding to an inner circumferential surface of the cylindrical part is covered by the cylindrical part, thereby reinforcing a strength of the balancer by the cylindrical part.
US10184199B2 Laundry treatment apparatus
A laundry treatment apparatus includes a cabinet having an upper surface, the upper surface being configured to receive an object thereon, a drawer adapted to be drawn from the cabinet, a drum disposed in the drawer and defining a space for receiving laundry, a driving unit configured to rotate the drum, a control unit configured to control the driving unit, and a connector unit configured to impact an ability of the control unit to control operation of the driving unit based on whether or not the object is placed on the upper surface of the cabinet by preventing the control unit from controlling operation of the driving unit based on the object being absent from the upper surface of the cabinet and by allowing the control unit to control operation of the driving unit based on the object being placed on the upper surface of the cabinet.
US10184195B2 Knitted component having an auxetic portion and a tensile element
A knitted component may include a knit element that has an auxetic portion configured to move between a first position and a second position as the knitted component stretches. The knitted component may also include a tensile strand inlaid within at least one of a course and a wale of the knit element, where the tensile strand extends through the auxetic portion, and where the tensile strand is selectively securable to the knit element via a securement device. The securement device may be spaced from the auxetic portion.
US10184194B2 Multi-material integrated knit thermal protection for industrial and vehicle applications
Knit fabrics having ceramic strands, thermal protective members formed therefrom and to their methods of construction are disclosed. Methods for fabricating thermal protection using multiple materials which may be concurrently knit are also disclosed. This unique capability to knit high temperature ceramic fibers concurrently with a load-relieving process aid, such as an inorganic or organic material (e.g., metal alloy or polymer), both small diameter wires within the knit as well as large diameter wires which provide structural support and allow for the creation of near net-shape performs at production level speed. Additionally, ceramic insulation can also be integrated concurrently to provide increased thermal protection.
US10184192B2 Apparatus for growing diamonds by microwave plasma chemical vapour deposition process and substrate stage used therein
An apparatus for growing diamonds, the apparatus comprising: one or more chambers, each chamber is in fluid connection with one or more other chambers, each chamber comprising one or more substrate stage assembly within the chamber to support a substrate stage having a plurality of diamond seeds disposed thereon.
US10184191B2 Method for manufacturing silicon carbide single crystal
Provided is a method for manufacturing a silicon carbide single crystal capable of easily separating a silicon carbide single crystal from a pedestal. The method includes the step of fixing a seed substrate to a pedestal with a stress buffer layer being interposed therebetween, the step of growing a silicon carbide single crystal on the seed substrate, the step of separating the silicon carbide single crystal from the pedestal at the stress buffer layer, and the step of removing a residue of the stress buffer layer adhering to the silicon carbide single crystal subjected to the step of separating.
US10184190B2 White appearing anodized films
The embodiments described herein relate to forming anodized films that have a white appearance. In some embodiments, an anodized film having pores with light diffusing pore walls created by varying the current density during an anodizing process is described. In some embodiments, an anodized film having light diffusing micro-cracks created by a laser cracking procedure is described. In some embodiments, a sputtered layer of light diffusing aluminum is provided below an anodized film. In some embodiments, light diffusing particles are infused within openings of an anodized layer.
US10184188B2 Apparatus for use in an electroetching or electrodeposition process and an electroetching or electrodeposition process
There is disclosed an apparatus for use in an electroetching or electrodeposition process in which material is etched from or deposited onto the surface of an electrically conductive component. The apparatus comprises a support for supporting the component within a tank containing an electrolytic solution; and a first-polarity electrode arranged to be located within the tank and immersed in the electrolytic solution and shaped to surround at least a part of the component in a contactless manner. In use, an electric field produced by the first-polarity electrode results in an electric variance between at least a part of the component and a second-polarity electrode having a polarity opposite to that of the first-polarity electrode. An electroetching and an electrodeposition process are also disclosed.
US10184187B2 Low stress hard coatings and applications thereof
In one aspect, coated cutting tools are described herein comprising a substrate and a coating comprising a refractory layer deposited by physical vapor deposition adhered to the substrate, the refractory layer comprising M1-xAlxN wherein x≥0.68 and M is titanium, chromium or zirconium, the refractory layer including a cubic crystalline phase and having hardness of at least 25 GPa.
US10184184B2 Process and device for forming a graphene layer
The invention concerns a method of forming a graphene layer involving: heating a support layer in a reaction chamber; and forming the graphene layer on a surface of the support layer by: a) during a first time period, introducing into the reaction chamber an organic compound gas to cause a formation of carbon atoms on the surface; b) during a second time period after the first time period, reducing a rate of introduction of the organic compound gas into the reaction chamber and introducing into the reaction chamber a further gas, wherein the further gas is a carbon etching gas; and repeating a) and b) one or more times.
US10184183B2 Substrate temperature monitoring
Embodiments disclosed herein generally relate to a substrate temperature monitoring system in a substrate support assembly. In one embodiment, the substrate support assembly includes a support plate and a substrate temperature monitoring system. The support plate has a top surface configured to support a substrate. The substrate temperature monitoring system is disposed in the substrate support plate. The substrate temperature monitoring system is configured to measure a temperature of the substrate from a bottom surface of the substrate. The substrate temperature monitoring system includes a window, a body, and a temperature sensor. The window is integrally formed in a top surface of the support plate. The body is embedded in the support plate, through the bottom surface. The body defines an interior passage. The temperature sensor is disposed in the interior passage beneath the window. The temperature sensor is configured to measure the temperature of the substrate.
US10184177B2 Substrate processing apparatus capable of adjusting flow rate of inert gas supplied to substrate
A system and technique that improve the quality of substrate processing may include a plurality of processing chambers; a vacuum transfer chamber; a plurality of transfer chambers; a plurality of gate valves; a plurality of first gas supply units configured to supply an inert gas to a substrate; a transfer robot; and a control unit for controlling the plurality of first gas supply units and the transfer robot to: supply the inert gas to the substrate at a first flow rate when a distance between a gas supply port and the substrate passing through the plurality of gate valves is a first distance; and supply the inert gas to the substrate at a second flow rate greater than the first flow rate when the distance between the gas supply port and the substrate is greater than the first distance when the substrate passes through the plurality of gate valves.
US10184171B2 Sputtering apparatus and method thereof
A method of forming a layer including disposing a first target and a second target to face each other with a first space therebetween, disposing a substrate to face the first space, generating plasma between the first target and the second target to perform sputtering on the substrate, disposing a capture net between the substrate and the the first space, and capturing anions and/or electrons that propagate toward the substrate from the first space.
US10184169B2 Method for supplying deposition material, method for producing substrate, control device and deposition device
Provided is a method for supplying a deposition material including a heating step of heating and evaporating a deposition material accommodated in a material accommodating section in which the deposition material is accommodated, a supply step of supplying the deposition material into the material accommodating section by feeding and melting a deposition material in a solid phase toward the melted deposition material in the material accommodating section, and a melted state detection step of detecting a melted state of the deposition material in the solid phase after supply in the supply step.
US10184168B2 IMC evaporator boat-thermal insulation cartridge assembly
An IMC evaporator boat-thermal insulation cartridge assembly that includes an IMC evaporator boat and a thermal insulation cartridge, which has a container containing a thermal insulation body containing a cavity. The IMC evaporator boat is received within the cavity so as to define an air space between the IMC evaporator boat and the thermal insulation body. A heater is contained within the air space.
US10184155B2 Genetic testing for improved cattle fertility
Arrays of nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods based on novel SNPs on genes of the bovine transforming growth factor-β (TGF-β) signaling pathway for improved bovine fertilization rate. The methods and compositions of the present invention are related to SNPs in the DNA-binding protein inhibitor 3 (ID3) gene, and in the bone morphogenetic protein 4 (BMP4) gene corresponding to position 2702 of SEQ ID NO: 2. Also disclosed are methods for determining viability of developing bovine embryos by measuring the expression level of one or more target genes in the TGF-signaling pathway, and selecting for implantation only embryos whose target gene expression level is not up-regulated.
US10184152B2 Transcriptional signature for chlamydial pelvic inflammatory disease
Methods are provided herein for determining the likelihood that a subject, such as an asymptomatic subject, has chlamydial pelvic inflammatory disease. In some embodiments, the method can determine the likelihood that a pharmaceutical agent is effective for treating a subject that has chlamydial pelvic inflammatory disease. In other specific non-limiting examples, the method predicts endometritis and elevated pathogen burden. The subject is a female, such as a human female.
US10184149B2 Biological analysis systems, devices, and methods
A device for performing biological sample reactions may include a plurality of flow cells configured to be mounted to a common microscope translation stage, wherein each flow cell is configured to receive at least one sample holder containing biological sample. Each flow cell also may be configured to be selectively placed in an open position for positioning the at least one sample holder into the flow cell and a closed position for reacting biological sample contained in the at least one sample holder. The plurality of flow cells may be configured to be selectively placed in the open position and the closed position independently of each other.
US10184147B2 Closed nucleic acid structures
The invention provides compositions and methods for making closed nucleic acid structures in which one or both strands are continuous. The closed nucleic acid structures can be used as sequencing templates among other applications.
US10184144B2 Identification and/or characterization of a microbial agent using taxonomic hierarchical classification
A method for identification and/or characterization of a microbial agent present in a sample includes a step of analytical test data (e.g., obtaining intrinsic fluorescence values over a range of emission wavelengths) from the microbial agent. The analytical test data is transformed thereby minimizing strain to strain variations within an organism group. With the aid of a programmed computer, a multi-level classification algorithm coded as a set of processing instructions operates on the transformed analytic test data. The multiple levels correspond to different levels in a taxonomic hierarchy for microbial agents suspected of being in the sample.
US10184143B2 Methods for increasing mannose content of recombinant proteins
The present invention relates to methods of upregulating the high mannose glycoform content of a recombinant protein during a mammalian cell culture by manipulating the mannose to total hexose ratio in the cell culture media formulation.
US10184139B2 Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion
The invention relates to recombinant host cells having at least one integrated polynucleotide encoding a polypeptide that catalyzes a step in a pyruvate-utilizing biosynthetic pathway, e.g., pyruvate to acetolactate conversion. The invention also relates to methods of increasing the biosynthetic production of isobutanol, 2,3-butanediol, 2-butanol or 2-butanone using such host cells.
US10184137B2 Method of producing isoprene monomer
A host cell includes a heterogeneous expression unit including: (a) a polynucleotide encoding a mevalonate kinase derived from a microorganism belonging to a genus selected from Methanocella, Corynebacterium, Methanosaeta, and Nitrosopumilus, and (b) a promoter operatively linked to the polynucleotide. The host cell is used to produce mevalonate kinase, mevalonate-5-phosphate, and isoprenoid compounds.
US10184136B2 Retroviral vectors
There is disclosed a retroviral vector comprising a primer binding site, a long terminal repeat and an RNA packaging sequence, wherein the RNA packaging sequence is located 3′ of the long terminal repeat and no long terminal repeat is located 3′ of the RNA packaging sequence such that reverse transcription initiated at the primer binding site does not lead to reverse transcription of the RNA packaging sequence into vector DNA in a target cell. Also described is a host cell, a virion, a pharmaceutical composition, a method and uses including or involving the vector described above. Further, a cell or transgenic animal produced by using the vector is also described.
US10184132B2 Methods of increasing abiotic stress tolerance, yield and/or biomass in plants
Provided are methods of increasing the tolerance of a plant to abiotic stresses and/or increasing the biomass and/or increasing the yield of a plant by expressing within the plant an exogenous polynucleotide encoding a polypeptide homologous to SEQ ID NO:236, such as the polynucleotide set forth by SEQ ID NO:1.
US10184130B2 Resource use efficiency improvement in plants
Polynucleotides and polypeptides incorporated into expression vectors are introduced into plants and were ectopically expressed. These polypeptides may confer at least one regulatory activity and increased yield, increased resource use efficiency, increased water use efficiency, increased light use efficiency, increased photosynthetic capacity, increased photosynthetic rate, increased photosynthetic resource use efficiency, greater vigor, and/or greater biomass as compared to a control plant.
US10184128B2 Method for high efficiency protein delivery into plastids
The present invention provides a recombinant DNA molecule encoding a fusion protein, comprising a first DNA sequence encoding a high-efficiency transit peptide operably linked to a second DNA sequence encoding a passenger protein, wherein the high-efficiency transit peptide is selected from the group consisting of transit peptides of the precursors of translocon at the inner envelope membrane of chloroplasts 40 kD (prTic40), chaperonin 10-2 (prCpn10-2), Fibrillin 1B (prFibrillin), ATP sulfurylase 1 (prAPS1), ATP sulfurylase 3 (prAPS3), 5′-adenylylsulfate reductase 3 (prAPR3), stromal ascorbate peroxidase (prsAPX), prTic40-E2A (a prTic40 variant), prCpn10-1-ΔC7C37S (a chaperonin 10-1 variant), a functional fragment of any of the transit peptides and an equivalent thereof. And the present invention also provides a method of high efficiency delivery of a protein into plastids using the high-efficiency transit peptides.
US10184126B2 Light-switchable gene expression system and the methods for controlling gene expression in prokaryotic bacterium
Provided is an optically controlled gene expression system of prokaryotic bacterium, comprising: a) a photosensitive recombinant transcription factor encoding gene, the photosensitive recombinant transcription factor is one fusion protein comprising a first polypeptide as the DNA bonding domain and a second polypeptide as the photosensitive domain; b) a target transcription unit comprising promoter or promoter-reaction element or reaction element-promoter containing at least one reaction element recognized/bound by the first polypeptide and the nucleic acid sequence to be transcribed. Also provided is a prokaryotic expression vector comprising said optically controlled gene expression system, and a method for regulating gene expression in a prokaryotic host cell by using the optically controlled gene expression system. Also provided is a reagent kit containing different components of the optically controlled gene expression system. The optically controlled gene expression system of prokaryotic bacterium has a quick, effective and powerful induction, is safer than other inducers, is of little or no toxicity, and can control gene expression both spatially and temporally, and can regulate many life processes of prokaryotic bacterium.
US10184124B2 RNA interference in ocular indications
The present invention relates to ocular administration of sd-rxRNA and rxRNAori molecules.
US10184121B2 Methods for removing viral contaminants from pancreatic extracts
Methods for screening pancrelipase for RNA virus contamination comprise removing free viral RNA from the pancrelipase, denaturing any viruses in the pancrelipase to release encapsidated RNA into the pancrelipase milieu, and detecting this released RNA. Removal of free viral RNA may comprise treating pancrelipase with RNase and DNase or precipitating the protein fraction of pancrelipase with a salt that precipitates the protein fraction while leaving nucleic acids such as RNA in solution. Pancrelipase substantially devoid of free nucleic acid is also provided.
US10184118B2 Cytochrome P450S and uses thereof
The invention relates to isolated cytochrome P450 polypeptides and nucleic acid molecules, as well as expression vectors and transgenic plants containing these molecules. In addition, the invention relates to uses of such molecules in methods of increasing the level of resistance against a disease caused by a plant pathogen in a transgenic plant, in methods for producing altered compounds, for example, hydroxylated compounds, and in methods of producing isoprenoid compounds.
US10184116B2 Chimeric genes for the catalytic protein of Oplophorus luciferase and use thereof
A novel luciferase that distinct from conventional luciferase has been desired. A luciferase mutant comprising the amino acid sequence of SEQ ID NO: 2 substituted at tyrosine at the position of 138, and at least 3 positions selected from the group consisting of isoleucine at the position of 90, proline at the position of 115, glutamine at the position of 124, and asparagine at the position of 166.
US10184115B2 Mutated cellobiose dehydrogenase with increased substrate specificity
The present invention relates to a modified cellobiose dehydrogenase (CDH) or its functional flavodehydrogenase domain having glucose oxidation activity and a reduced maltose oxidation activity as compared to the unmodified CDH or its functional flavodehydrogenase domain, nucleic acids encoding said enzyme or domain, electrodes with said enzyme or domain and methods of producing and using the same.
US10184111B2 Tissue processing device and associated systems and methods
Tissue processing devices are provided. The tissue processing devices can be used to process and transport tissue in a closed and continuous environment. The devices can be used for adipose tissue transfer, including autologous fat grafting.
US10184109B2 Method for obtaining differentiated cells and/or differentiated cell products from undifferentiated cell and a method of perfusion culture
Disclosed is a method for obtaining differentiated cells and/or differentiated cell products, including the steps of: introducing undifferentiated cells into a perfused organ or living tissue; subjecting the undifferentiated cells introduced to perfusion culture together with the organ or living tissue so as to allow the undifferentiated cells to differentiate, thereby obtaining differentiated cells and/or differentiated cell products; collecting a perfusion culture solution that contains the resulting differentiated cells and/or differentiated cell products; and obtaining the differentiated cells and/or differentiated cell products contained in the collected perfusion culture solution.
US10184104B2 Automated system for cultivating transgenic C. elegans
The present invention provides a self-draining well plate cassette and an automated system for cultivating C. elegans comprising a housing, a well plate assembly having at least two of the self-draining well plate cassettes, a liquid dispensing assembly operated by a first three axes positioner, a wash and imaging assembly operated by a second three axis positioner, a reagent assembly, a pipette tip holder, and a controller. The present invention further provides a method of using the above-described system to cultivate C. elegans.
US10184101B2 Nutrient medium unit and method for holding a filter from a filtration device
The invention relates to a nutrient medium unit for holding a filter of a filtration device, comprising a lower part that is filled with the nutrient medium and a lid, the latter having a fixing edge that protrudes into the lower part and that can be connected to an edge of the filter by means of an adhesive bond in order to remove said filter from the filtration device. The invention also relates to a method for the microbiological analysis of liquid samples, according to which a membrane filter is lifted off a filter support and laid on the surface of a nutrient medium that is situated in a lower part of a nutrient medium unit. The lower part is then covered by a lid, the latter being placed on the membrane filter lying on the filter support in such a way that a fixing edge located in the lid is connected to an edge of the filter by means of an adhesive bond. The lid and the attached filter are lifted off the filter support and placed on the dish-shaped lower part of the nutrient medium unit.
US10184094B2 Mixture, their manufacture and use
Mixtures comprising a mixture of compounds (A), said mixture comprising a mixture of compounds according to the general formula (I) wherein R1 is C1-C4-alkyl, linear or branched, or hydrogen, R2 is —CH2CH2R1, each G1 is glucose or xylose, wherein in the range of from 70 to 95% mole-% are glucose and from 5 to 30 mole-% are xylose, the average of x is in the range of from 1.1 to 4.
US10184092B2 Ionic liquid, lubricant, and magnetic recording medium
A lubricant including: an ionic liquid, which includes a conjugate acid (B+) and a conjugate base (X−), and is protic, wherein the ionic liquid is represented by the following general formula (1), and wherein the conjugate base is a conjugate base of sulfonic acid, a conjugate base of sulfonimide, or a conjugate base of trisulfonylmethide: where R1 and R2 each represent a hydrogen atom or R1 and R2 form a benzene ring together with carbon atoms to which R1 and R2 are bonded, R3 represents a to straight-chain hydrocarbon group having 10 or more carbon atoms, and R4 represents a hydrogen atom or a hydrocarbon group in the general formula (1).
US10184091B2 Yttrium and magnesium based vanadium corrosion inhibitors
A process based on the combined use of yttrium and magnesium to inhibit vanadium corrosion of high temperature parts of thermal equipment. The combined use of yttrium and magnesium, applied in a variable yttrium/magnesium ratio, compared with conventional magnesium inhibition, may reduce emission of magnesium vanadate and minimize losses of performance due to fouling of the high temperature parts, including in the presence of alkali metals. Further, compared with inhibition based on yttrium alone, it may reduce the inhibition cost and reinforce the protection against combined vanadium pentoxide and sodium sulfate corrosion.
US10184090B2 Combined dehydration of gas and inhibition of liquid from a well stream
A method and system for dehydration of a gas phase and hydrate inhibition of a liquid hydrocarbon phase in a multiphase hydrocarbon fluid stream containing water. The method may include (i) separating the hydrocarbon fluid stream into a liquid phase and a first gas phase, (ii) adding hydrate inhibitor to the first gas phase, and (iii) separating off condensed liquids and a second gas phase. The first gas phase has a water dew point that is lower than the initial multiphase hydrocarbon fluid stream and the second gas phase has a lower water dew point than the first gas phase. The hydrate inhibitor has a water content that is low enough to enable it to dry the first gas phase, the hydrate inhibitor being separated off with the condensed liquids and mixed with a part or all of the liquid phase from the separation to inhibit the liquid phase.
US10184089B2 Process for the aromatization of dilute ethylene
Described herein are processes for the conversion of ethylene into C5+ olefins, naphthenics, and aromatics via a dual catalyst reaction utilizing a dehydroaromatization catalyst.
US10184086B2 Method and article for cracking hydrocarbon, and method for protecting article against coking during hydrocarbon cracking
A method for cracking hydrocarbon includes providing a feedstock comprising steam and hydrocarbon, and feeding the feedstock into a device having an inner surface accessible to the feedstock. The inner surface includes a compound of formula An+1BnO3n+1, wherein A includes at least one alkaline earth metal, B includes at least one transition metal, O is oxygen, and 1≤n≤20.
US10184085B2 Method for catalytic deoxygenation of natural oils and greases
A method for deoxygenating renewable oils comprised of natural oils or greases or derivatives thereof containing triglycerides or free fatty acids includes the steps of: providing a catalyst comprising a support predominantly comprised of alumina with metal compounds provided on the support based on Mo and at least one selected from the group consisting of Ni and Co, and at least one selected from the group consisting of Cu and Cr, and contacting the renewable oils with the catalyst under conditions sufficient to deoxygenate the renewable oils.
US10184081B2 Apparatus for multistage thermal treatment of rubber waste, in particular scrap tires
A process for multistage thermal treatment of rubber waste, in particular scrap tires, is proposed. The process comprises several steps of transferring a product granulate of rubber waste into three different sequencing heating zones of a reactor (10). In the heating zones (11a, 11b, 11c) the product granulate is heated at a first temperature between 100° to 200° C., preferably 150° to 180° C., then at a second temperature between 200° to 350° C. and at a third temperature between 300° to 600° C. The temperature is maintained until such time that no further oil is emitted within the respective heating zone. As a final step, the product granulate is removed from the reactor (10) and the desirable solid materials are separated.
US10184080B2 Liquid crystal materials, methods of fabricating liquid crystal display panels and liquid crystal display panels
The present application provides a liquid crystal material, a method of fabricating a liquid crystal display panel, and a liquid crystal display panel. The liquid crystal material of the present application includes liquid crystal molecules, polymerizable monomers and a reactive vertical alignment material, the polymerizable monomers and the reactive vertical alignment material can occur a polymerization under ultraviolet irradiation to form a polymer, while the polymer deposits on a substrate to form a polymer film capable of replacing the PI alignment film, the reactive vertical alignment material includes a polymerizable group L that strengthens polymerization ability of the reactive vertical alignment material, increases compactness of forming the polymer film, improves morphology of the polymer film, and enhances panel quality. The method of fabricating the liquid crystal display panel of the present application eliminates the fabricating process of the PI alignment film, the method has simple process and low cost. The liquid crystal display panel utilizes the polymer film, which is obtained by polymerizing the polymerizable monomers and the reactive vertical alignment material, to replace the PI alignment film, so as to greatly enhance quality of the panel, and to have a low fabricating cost.
US10184078B2 Organic electroluminescent device
An organic electroluminescent device of which emission life may be improved. The organic electroluminescent device includes an anode, an emission layer, and an anode-side hole transport layer provided between the anode and the emission layer and including an anode-side hole transport material. An electron accepting material is doped in the anode-side hole transport layer. An intermediate hole transport material layer is provided between the anode-side hole transport layer and the emission layer and includes an intermediate hole transport material, and an emission layer-side hole transport layer is provided between the intermediate hole transport material layer and the emission layer and adjacent to the emission layer. The emission layer-side hole transport layer includes an emission layer-side hole transport material represented by the following Formula 1.
US10184074B2 Compositions comprising tetrafluoropropene and methods of use thereof
The present invention relates to a composition comprising HFO-1234yf, or trans-HFO-1234ze, or a mixture thereof; HFC-32; and HFC-152a, HFO-1243zf, or a mixture thereof, wherein said composition is selected from the group consisting of: (I) a first composition, wherein said HFO-1234yf or trans-HFO-1234ze or a mixture thereof is at least 56 weight percent of said first composition; (II) a second composition, wherein said HFC-32 is at most 29 weight percent of said second composition; (III) a third composition, wherein said HFC-152a is at least 56 weight percent said third composition; (IV) a fourth composition, wherein said HFC-32 is at least 56 weight percent of said fourth composition; (V) a fifth composition comprising trans-HFO-1234ze, HFC-32, and HFC-152a, HFO-1243zf, or a mixture thereof; and (VI) a sixth composition, wherein said HFO-1243zf or mixture thereof with HFC-152a is at most 20 weight percent of said sixth composition.
US10184073B2 Emulsion including polymers containing a 1,1-disubstituted alkene compound, adhesives, coatings, and methods thereof
The present teachings show that it is possible to polymerize 1,1-disubstituted alkene compounds in an emulsion (for example using a water based carrier liquid), despite the possible reactions between the monomer and water. Polymerization of 1,1-disubstituted alkene compounds in an emulsion provides opportunities to better control the polymerization compared with bulk polymerization. The emulsion polymerization techniques can be employed for preparing homopolymers, copolymers (e.g., random copolymers), and block copolymers.
US10184072B2 Coating agent, decorative film, and article
An object of the present invention is to provide a coating agent giving a coating film that has good adhesion and stability over time, a decorative film having at least one layer formed from the coating agent; and an article decorated with the decorative film. The coating agent of the present invention contains, in a specific ratio, an olefin polymer (A) having a heat of fusion of in the range of 0 to 50 J/g and having a weight average molecular weight (Mw) as measured by GPC of 1×104 to 1000×104, a hydrocarbon-based synthetic oil (B) having a 40° C. kinematic viscosity of 30 to 500,000 cSt, and a tackifier (C) having an acid value of 10 or more and having a weight average molecular weight (Mw) of 0.9×103 to 3×103.
US10184071B2 Adhesive tape for connecting secondary battery electrodes
Disclosed herein is an adhesive tape for connecting secondary battery electrodes which prevents an adhesive from leaking to electrodes during electrode processing processes even though the adhesive tape for connecting the electrodes is adhered or which prevents the adhesive from leaking to the electrodes wound near the adhesive tape in a case that the electrode substrates are wound in a roll type in order to continuously connect electrode substrates of the front and rear ends during a secondary battery electrode manufacturing process, thereby preventing the electrodes from being damaged and from being unacceptable. The adhesive tape for connecting secondary battery electrodes comprises: a base film formed in a thin plate type and made of a synthetic resin; and an adhesive layer formed on the lower surface of the base film by applying an adhesive to the central portion of the base film, except the left and right peripheries.
US10184070B2 Thermosettable adhesive tape, articles and methods
A thermosettable pressure sensitive adhesive tape comprising at least first and second adhesive layers bonded together. Each of the adhesive layers comprises a thermosettable pressure sensitive adhesive, which is the photo-polymerization reaction product of starting materials. The starting materials for each adhesive layer comprises at least a photo-polymerizable acrylic component and a thermosettable epoxy component. The thermosettable pressure sensitive adhesive, used for either of the two adhesive layers, is not black when fully cured without the presence of a black coloring pigment. The first adhesive layer is made from a layer of starting materials that is thin enough to allow substantial photo-polymerization of the starting materials, even with the starting materials containing a sufficient amount of a black coloring pigment to cause the first adhesive to have a black color after the first adhesive is substantially cured. The second adhesive layer is made from a layer of starting materials which has a thickness that would be sufficiently thick to prevent substantial photo-polymerization (e.g., with UV light) of the starting materials, if the starting materials contained enough of a black coloring pigment to cause the second adhesive to have a black color after the second adhesive is cured.
US10184064B2 Inorganic composition for transferring a fine unevenness
Disclosed is an inorganic composition for transferring a fine unevenness by which a fine unevenness made of an inorganic material capable of controlling a refractive index can be fabricated through a suitable transfer process. The composition according to the present invention contains a silicone compound and at least two types of metal alkoxides, wherein the metal alkoxides include a metal alkoxide having a metal species M1 (where M1 denotes at least one metal element selected from a group consisting of Ti, Zr, Zn, Sn, B, In, and Al) and a metal alkoxide having a metal species Si. In addition, a ratio between a molarity CM1 of the metal alkoxide having the metal species M1 and a molarity CSi of the metal alkoxide having the metal species Si in the inorganic composition for transferring a fine unevenness satisfies a condition of 0.2≤CM1/CSi≤24.
US10184061B2 Efficient waterborne nano-silicon rubber sealing waterproof agent
The present invention relates to an efficient waterborne nano-silicon rubber sealing waterproof agent, comprising following components in parts by weight: 10˜90 parts of nano-silica gel, 10˜100 parts of nano-diatomaceous earth, 5˜150 parts of nano polyurethane, 15˜200 parts of nano inorganic dry powder, 10˜100 parts of nano methyl cellulose, 10˜150 parts of a chelating agent, 15˜200 parts of an expansion agent, 10˜250 parts of a strengthening agent, 5˜100 parts of an antifreezing agent, 2˜150 parts of a heat-resistant agent and 10˜100 parts of an acid and alkali-resistant agent. The efficient waterborne nano-silicon rubber sealing waterproof agent has good waterproofness, permeability, film forming property, elasticity, adhesion, water resistance and heat, humid and high temperature resistance, is suitable for being used for waterproof, anti-seepage and anti-leakage repair projects of underground engineering and roofing, and is an excellent vapor barrier material in a refrigerating chamber.
US10184059B2 Nanometal-nanocarbon hybrid material and method of manufacturing the same
Disclosed are a nanometal-nanocarbon hybrid material and a method of manufacturing the same, the method including modifying the surface of nanocarbon to introduce a functional group to conductive nanocarbon; mixing the surface-modified nanocarbon with an isocyanate-based compound and a pyrimidine-based compound and allowing them to react, thus forming a nanocarbon dispersion reactive to metal ions; adding the nanocarbon dispersion with a metal salt precursor, a reducing agent and a solvent, thus manufacturing nanometal particles; and separating a hybrid of the nanometal particles having the nanocarbon bound thereto. Thereby, nanocarbon is mixed with an isocyanate-based compound and a pyrimidine-based compound and then allowed to react, whereby the nanocarbon reactive with metal ions is used as an additive, thus obtaining a nanometal having a low-dimensional shape having less than three dimensions. Also, a nanometal can be hybridized with nanocarbon simultaneously with the formation of the nanometal, and solvent dispersibility is ensured by a functional group formed by mixing and reacting an isocyanate-based compound and a pyrimidine-based compound, ultimately facilitating the preparation of conductive ink or paste.
US10184058B2 Ink composition for detecting plasma treatment and indicator for detecting plasma treatment
An object of the present invention is to provide: a plasma treatment detection indicator comprising a color-changing layer that exhibits improved heat resistance so that the layer does not change color even when overheated at up to about 170° C. as a result of a plasma-generating gas not being supplied or being insufficient due to a defect in a plasma treatment device; and an ink composition for detecting plasma treatment, the composition being for forming the color-changing layer. The ink composition for detecting plasma treatment includes a colorant and a binder resin containing a phenol resin, and the plasma treatment detection indicator uses the ink composition.
US10184054B2 Coating for the mitigation of metal whiskers
A coating for mitigating metal whiskers on a metal surface includes a polymeric coating material; and a metal ion complexing agent impregnated within the polymeric coating material, the metal ion complexing agent having a standard reduction potential (E°) that is greater than a metal in the metal surface.
US10184049B2 Stain repellent compositions and applications thereof
The present invention provides fluorinated compounds as well as dispersions of the fluorinated compounds. The fluorinated compounds described herein, in some embodiments, can be applied substrates such as textiles, including carpet and other floor coverings.
US10184045B2 Thermoplastic polyolefin with reduced gloss for non-carpeted flooring
The present invention is directed to an elastomer composition comprising an ethylene/α-olefin/diene modified interpolymer, a very low density polyethylene component, and a propylene polymer component, wherein the propylene polymer component comprises at least one branched polypropylene. The inventive compositions are particularly suitable for fabricating thermoformed non-carpet automotive flooring.
US10184036B2 Composite resin pre-expanded particles containing carbon black and method for producing same, and expanded molded article
Carbon black-containing composite resin pre-expanded particles comprising 100 to 400 parts by mass of a polystyrene-based resin with respect to 100 parts by mass of a carbon black-containing polyolefin-based resin; having a carbon black content of 0.5 to 5.0% by mass and a bulk density of 0.015 to 0.25 g/cm3; and having an outermost layer of 30 to 80 pm after undergoing the following tests: (a) one of the carbon black-containing composite resin pre-expanded particles is sliced into a 1-mm slice in such a way that cross-section surfaces of cells are exposed on both surfaces of the slice; (b) the obtained slice is immersed in toluene at 25° C. for 24 hours to extract a polystyrene-based resin component as described above; (c) the cross-section surface of the slice is then subjected to magnified photographing by a microscope; (d) the obtained microscope image is observed.
US10184034B2 Carbon fiber forming raw material, formed material, and carbon fiber-reinforced composite material
The carbon fiber forming raw material is a carbon fiber forming raw material (Z) as a prepreg including sizing agent-coated carbon fibers and a thermosetting resin or a carbon fiber forming raw material (Y) as a forming material that includes sizing agent-coated carbon fibers and has a woven fabric form or a braid form. The sizing agent includes components (A) and (B). The component (A) is an epoxy compound having two or more epoxy groups or two or more types of functional groups. The component (B) is one or more compounds selected from the group consisting of a tertiary amine compound, a tertiary amine salt, a quaternary ammonium salt, a quaternary phosphonium salt, and a phosphine compound. The component (B) is contained in an amount of 0.1 to 25 parts by mass relative to 100 parts by mass of the component (A).
US10184033B1 Synthesis of silver-PMMA nanocomposite film
The synthesis of a silver-PMMA nanocomposite film includes mixing an aqueous extract of Trigonella foenum-graecum (also known as Helba and fenugreek) seeds with an aqueous solution of silver nitrate, thereby reducing the silver ions to silver metal nanoparticles. A solution of the silver nanoparticles is added to a solution of PMMA [poly (methyl methacrylate)] in N′N-dimethylformamide (DMF) with stirring at 90° C. A light brown solution of silver colloids develops, which is cast in a glass plate and the DMF is evaporated at room temperature, leaving a silver-PMMA nanocomposite film. Testing on water shows the silver-PMMA nanocomposite film prevents or inhibits growth of microbes, suggesting use as an antimicrobial or antibacterial agent, e.g., in water purification.
US10184032B2 Method for preparing a chitosan-based matrix comprising a fiber reinforcement member
The present invention relates to a method for preparing a chitosan-based matrix comprising the following steps: a) two separate chitosan porous layers obtained from lyophilization of layers of one or more solutions of chitosan are provided, b) the chitosan porous layers of a) are neutralized and washed, c) a face of each chitosan porous layer is acidified with an acid, d) a fiber reinforcement member is provided and positioned between the two acidified faces of the two chitosan porous layers, e) the two chitosan porous layers and the fiber reinforcement member are let to dry to obtain a matrix having the fiber reinforcement member embedded therein. The invention also relates to an implant comprising a matrix obtained according to such a method.
US10184025B2 Methods for preparing aqueous suspension of precious metal nanoparticles
The present disclosure is directed to methods of preparing stable suspensions of precious metal nanoparticles and methods for attaching bio-molecules to the nanoparticles. The formation of nanoparticles can be accomplished by either chemical synthesis or pulsed laser ablation in a liquid. The present disclosure reveals the importance of controlling the conductivity of the dispersion medium during pulsed laser ablation in a liquid to control the particle size of the nanoparticles. The present disclosure also reveals the importance of adjusting and maintaining the conductivity in a range of 25 μS/cm or less during storage of the nanoparticles and just prior to performing bioconjugation reactions. The control of conductivity is an important process for maintaining the nanoparticles as a stable non-aggregated colloidal suspension in a dispersion medium.
US10184024B2 Carmine colorants
The present disclosure provides a modified carmine which can comprise polymers, such as, polyesters, or conjugating molecules, such as, polycarboxylic acids.
US10184022B2 Polymers, composites, and methods for making polymers and composites
Polymeric materials and methods for making the polymeric materials utilizing bisphenolic stillbottoms, lignosulfonates, or both are disclosed. In one embodiment, a polymer is provided that includes a condensate of bisphenolic stillbottoms, an optional phenolic compound independent of bisphenolic stillbottoms, an aldehyde, and a lignosulfonate compound. The condensate may further include an amino compound, a catalyst, or combinations thereof. Alternatively, the polymer may be free of a phenolic compound independent of bisphenolic stillbottoms. The polymers may be used in the manufacture of articles including composites, laminates and paper products.
US10184017B2 Catalyst component for propene polymerization, preparation method thereof, and catalyst containing the same
The present invention discloses a catalyst component for propene polymerization, comprising titanium, magnesium, halogen, and internal electron donor A, wherein said internal electron donor A is selected from the compounds as shown in Formula I, in Formula I, R is selected from hydrogen, hydroxyl, and substituted or unsubstituted C1-C30 hydrocarbyl, preferably from hydrogen, hydroxyl, and substituted or unsubstituted C1-C20 alkyl, C6-C30 aryl, C6-C30 heteroaryl, C7-C30 alkylaryl and C7-C30 arylalkyl; R1 and R2 may be identical to or different from each other, and are selected from hydrogen and substituted or unsubstituted C1-C30 hydrocarbyl, preferably from hydrogen and substituted or unsubstituted C1-C20 alkyl, C6-C30 aryl, C7-C30 alkylaryl and C7-C30 arylalkyl. According to the present invention, by using the compound as shown in Formula I as internal electron donor compound for propene polymerization, the catalyst has a higher activity, and a slow rate of delay of activity. The obtained polymer has not only a wider molecular weight distribution, but also a high melt index and isotacticity.
US10184015B2 Process for producing (meth)acrylic resin composition
A method for producing a (meth)acrylic resin composition, comprising: continuously feeding reaction starting materials to a tank reactor, the reaction starting materials comprising a polymerizable monomer component, a chain transfer agent and a radical polymerization initiator, the polymerizable monomer component comprising 50 to 100% by mass of methyl methacrylate, 0 to 20% by mass of an acrylic acid alkyl ester and 0 to 30% by mass of an additional monomer; conducting bulk polymerization of the polymerizable monomer component at a polymerization conversion ratio of 40 to 70% by mass to obtain a liquid containing a (meth)acrylic resin; continuously feeding the resulting liquid to a vented extruder to separate volatile component from the (meth)acrylic resin; conducting distillation using an atmospheric distillation column to separate the volatile component into a high boiling fraction (C1) and a low boiling fraction (A1); and conducting distillation using a vacuum distillation column having a pressure of −50 kPaG to −101 kPaG at the top of the vacuum distillation column to separate the high boiling fraction (C1) into a high boiling fraction (C2) and a low boiling fraction (A2); reusing the low boiling fraction (A1) and the low boiling fraction (A2) as part of the reaction starting materials.
US10184012B2 Modified butadiene-based polymer and modifier useful for preparing the same
The present invention provides a modified butadiene-based polymer capable of enhancing dispersability of an inorganic filler when used in a rubber composition, and enhancing viscoelasticity, a tensile property and processibility of the rubber composition in a balanced way from an interaction with the inorganic filler, and a modifier useful for preparing the same.
US10184011B2 Hemostatic devices with improved properties and methods of making same
Hemostatic devices and methods of making same are disclosed. Disclosed hemostatic devices include biocompatible non-oxidized regenerated cellulose. The disclosed hemostatic devices are effective in providing and maintaining hemostasis in cases of moderate to severe bleeding caused by non-compressional and/or non-tourniquetable injuries, among other things. The disclosed methods enable manufacture of a bioabsorbable, biocompatible, biodegradable carboxylmethyl cellulose having high stability and high adherence.
US10184009B2 Mutant interleukin-2 polypeptides
The present invention generally relates to mutant interleukin-2 polypeptides that exhibit reduced affinity to the α-subunit of the IL-2 receptor, for use as immunotherapeutic agents. In addition, the invention relates to immunoconjugates comprising said mutant IL-2 polypeptides, polynucleotide molecules encoding the mutant IL-2 polypeptides or immunoconjugates, and vectors and host cells comprising such polynucleotide molecules. The invention further relates to methods for producing the mutant IL-2 polypeptides or immunoconjugates, pharmaceutical compositions comprising the same, and uses thereof.
US10184008B2 Blood brain barrier transport molecules and uses thereof
The disclosure provides transporter molecules capable of carrying agents of interest across the blood brain barrier. Also provided are polynucleotides encoding transporter molecules, methods making transporter molecules, and methods of using transporter molecules, e.g., for the diagnosis, prevention, or treatment of central nervous system diseases, disorders, or injuries.
US10184007B2 Methods of treating a kit-associated cancer by administering anti-kit antibodies
Provided herein, in one aspect, are antibodies that immunospecifically bind to a human KIT antigen comprising the fourth and/or fifth extracellular Ig-like domains (that is, D4 and/or D5 domains), polynucleotides comprising nucleotide sequences encoding such antibodies, and expression vectors and host cells for producing such antibodies. The antibodies can inhibit KIT activity, such as ligand-induced receptor phosphorylation. Also provided herein are kits and pharmaceutical compositions comprising antibodies that specifically bind to a KIT antigen, as well as methods of treating or managing a KIT-associated disorder or disease and methods of diagnosing a KIT-associated disorder or disease using the antibodies described herein.
US10184006B2 Biomarkers for predicting outcomes of cancer therapy with ErbB3 inhibitors
Methods for predicting a therapeutic response in a patient (e.g., a cancer patient) to ErbB3 inhibitors, and methods of treating a cancer patient with targeted therapies.
US10184005B2 Generation and profiling of fully human HuCAL GOLD-derived therapeutic antibodies specific for human CD38
The present invention provides novel antibodies and methods for using recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for CD38, which plays an integral role in various disorders or conditions. These methods take advantage of newly discovered antibodies and surprising properties of such antibodies, such as the ability to bind CD38 of minipig origin and the ability to induce, by cross-linking, specific killing of cells that express CD38. These antibodies as well as the novel methods for using those antibodies can be used to treat, for example, hematological malignancies such as multiple myeloma.
US10184004B2 CD47 targeted therapies for the treatment of infectious disease
Methods are provided for treating a subject with for an intracellular pathogen infection, by administering an agent that reduces the binding of CD47 on a infected cell to SIRPα on a host phagocytic cell, in an effective dose for increasing the phagocytosis of infected cells.
US10183997B2 Compositions and methods related to anti-CD19 antibody drug conjugates
In some aspects, the invention relates to an antibody-drug conjugate, comprising an anti-CD19 antibody; a linker; and an active agent. The antibody-drug conjugate may comprise a self-immolative group. The linker may comprise an O-substituted oxime, e.g., wherein the oxygen atom of the oxime is substituted with a group that covalently links the oxime to the active agent; and the carbon atom of the oxime is substituted with a group that covalently links the oxime to the antibody.
US10183994B2 Anti-TNFα antibodies with pH-dependent antigen binding for improved target clearence
The invention relates to anti-TNFα antibodies which are engineered to exhibit a pH-sensitive antigen binding. The invention is preferably directed to anti-TNFα antibody adalimumab (Humira®) or biologically active variants and fragments thereof, wherein the original adalimumab antibody or variant or fragment thereof is engineered by modifications of amino acid sequence within the variable regions. Specifically, the invention relates to adalimumab or biologically active variants or fragments thereof, wherein the CDR domains are modified by replacing one or more amino acid residues by histidine residues.
US10183993B2 Compositions and methods for treating cancer with anti-mesothelin immunotherapy
Chimeric antigen receptors containing mesothelin antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed.
US10183989B2 Methods of treating ocular diseases
A method of treating a complement mediated ocular inflammation, hemorrhaging and fibrosis, and the pathological consequences thereof, in a subject in need thereof, the method comprising of administering to the subject a therapeutically effective amount of an antibody which inhibits the alternative complement pathway, wherein the antibody administered is effective for inhibiting complement mediated ocular inflammation, hemorrhaging and fibrosis, and the pathological consequences thereof.
US10183986B2 Trimeric collagen scaffold antibodies
A collagen scaffold domain, including a collagenous or collagen-like domain, which directs self-trimerization is provided. The collagen scaffold domain can be fused to one or more heterologous domains, such as an antibody domain. Methods for generating and using the scaffold domains and fusion proteins are also provided.
US10183985B2 Compositions and methods for rendering tumor cells susceptible to CD8+ T cell-mediated killing
The present invention provides an immunoconjugate having the formula: T-c-En-c-Fcn or T-c-Fcn-c-En; wherein, T is a single chain variable portion fragment of a monoclonal antibody (scFv) directed to a target protein, polypeptide, or fragment thereof, which is highly expressed on cancer cells; E is two or more foreign immunogenic CD8+ T cell antigenic epitopes; c is a peptide or polypeptide fragment thereof, capable of being cleaved by a specific protease; and Fc is two or more Fc portions of an IgG antibody. Nucleic acid sequences encoding the same and vectors containing said nucleic acid sequences are also provided. Methods of making the immunoconjugate, along with methods of making target cells susceptible to CTL mediated cell killing, and methods for treatment of cancers are also provided.
US10183983B2 Nucleic acids encoding fusion proteins comprising PDGF and VEGF binding portions and methods of using thereof
The present provides fusion proteins comprising PDGF and VEGF binding portions, and recombinant viral particles encoding the fusion proteins. Compositions comprising the fusion proteins and viral particles as well as methods of using the same are also provided.
US10183979B2 Fusion polypeptides comprising mucin-domain polypeptide linkers
The invention provides fusion proteins having improved bioactivity comprising a first polypeptide fusion partner and a second polypeptide fusion partner wherein the first fusion partner is linked to the second fusion partner by a mucin-domain polypeptide linker and wherein the bioactivity of the fusion protein of the invention is improved as compared to fusion of the first polypeptide fusion partner and the second polypeptide fusion partner in the absence of the mucin-domain polypeptide linker. Mucin-domain polypeptide linkers comprise a mucin domain that is rich in potential glycosylation sites, and has a high content of serine and/or threonine and proline, which can represent greater than 40% of the amino acids within the mucin domain and further comprise at least about 60% of its mass due to the glycans.
US10183976B2 Method for producing factor H from a plasma precipitation fraction
The present disclosure provides, among other aspects, improved methods for the manufacture of Factor H compositions from plasma precipitation fractions. In some aspects, the methods include an improved process step for extracting Factor H from a plasma precipitate fraction with reduced co-extraction of amidolytic activities. In other aspects, the methods include a heat treatment step for reducing impurities, such as amidolytic enzymes, from a Factor H composition. In yet other aspects, the methods include improved anion exchange, heparin affinity, and/or mixed mode chromatographic enrichment of Factor H. In still other aspects, the improved methods include a combination of the individual improved process steps disclosed herein.
US10183972B2 BK channel-modulating peptides and their use
The present invention concerns peptides and nucleic acids encoding the peptides, and their use for modulating large conductance Ca2+ activated K+ (BK) channel activity in cells; for treating conditions such as presbycusis (age-related hearing loss), audiogenic seizures, alcohol addiction, cancer, and neurodegenerative disease; and for delivering a cargo moiety to the brain of a subject through the blood-brain barrier.
US10183971B2 SAA-domain-specific antibodies and peptide antagonists and use thereof to treat inflammatory diseases
Isolated SAA peptides, fusion proteins and compositions comprising such are provided as are domain-specific SAA antibodies. Methods of treating sepsis and endotoxemia are also provided.
US10183969B2 Method for purification of target polypeptides
The present invention relates to a process for purification of a target molecule, comprising the steps: (a) contacting a target molecule, and a population of target binding polypeptides (TBP), in solution for a sufficient time to allow complex formation; and (b) isolating the target from the complex from (a) by subsequent purification steps, wherein (i) the target binding polypeptides have at least two binding functionalities; a first binding functionality towards the target and a second binding functionality towards a catching ligand comprised in a solid support; and (ii) the first binding functionality comprises at least two binding sites for the target, and the target comp¬ rises at least two binding sites for the TBP.
US10183968B2 Methods of preparing lyophilized spherical-shaped pellets of biological materials
Methods for preparing lyophilized pellets of biological materials are described. The pellets have a substantially spherical shape and are prepared by freezing droplets of a liquid composition of a desired biological material on a flat, solid surface, in particular, a surface that does not have any cavities, followed by lyophilizing the frozen droplets. These methods are useful for preparing lyophilized pellets having a high concentration of a desired biological material, in particular a therapeutic protein or vaccine, and which have a faster reconstitution time than lyophilized powder cakes prepared in vials.
US10183963B2 Utility of nematode small molecules
The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
US10183962B2 Synthetic oligomers of Neisseria meningitis serogroup X and process of preparing them
The present invention relates to synthesis of novel higher oligomers and process of preparing the same. In particular the present invention relates to the chemical synthesis of oligomers of Neisseria meningitidis serogroup X (‘hereinafter Men-X), more particularly tetramer. The present invention provides Men-X capsular oligomers obtained from synthetic pathway using purified saccharides of specific chain length and provides said novel oligomers as candidates for the development of conjugate vaccine against bacterial meningitis caused due to Men-X infections.
US10183959B2 Compounds with phosphine oxide and amine functions, useful as uranium (VI) ligands, and uses thereof, in particular for extracting uranium(VI) from aqueous solutions of sulphuric acid
The invention relates to compounds which correspond to the general formula (I) below: in which: R1 and R2 represent, independently of one another, a C4 to C12 acyclic hydrocarbon group; R3 represents H; a C1 to C12 acyclic hydrocarbon group with optionally one or more heteroatoms; a C5 or C6 cyclic hydrocarbon group; or a 5- or 6-membered heterocyclic group; R4 represents H or a C1 to C12 acyclic hydrocarbon group with optionally one or more heteroatoms; R5 and R6 represent, independently of one another, H; a C1 to C12 acyclic hydrocarbon group with optionally one or more heteroatoms; a C5 or C6 cyclic hydrocarbon group; or a 5- or 6-membered heterocyclic group; on the condition however that R5 and R6 do not each represent H. The invention also relates to the uses of these compounds as uranium(VI) ligands, in particular for extracting uranium(VI) from an aqueous solution of sulphuric acid, and also to a method that makes it possible to recover the uranium(VI) present in an aqueous solution of sulphuric acid resulting from the attack of a uranium ore by sulphuric acid and using said the compounds.
US10183958B2 Method of producing organohalosilanes
A method for producing an organohalosilanes comprising reacting an organic compound comprising a halogen-substituted or unsubstituted alkane, a halogen-substituted or unsubstituted alkene, or an aromatic compound and at least one hydridohalosilane of formula RnSiHmX4-m-n, wherein each R is independently C-1-C-14 hydrocarbyl or C-1-C-14 halogen-substituted hydrocarbyl, X is fluoro, chloro, bromo, or iodo, n is 0, 1, or 2, m is 1, 2 or 3, and m+n=1, 2 or 3, in the presence of a heterogeneous catalyst comprising an oxide of one or more of the elements Sc, Y, Ti, Zr, Hf, B, Al, Ga, In, C, Si, Ge, Sn, or Pb, at a temperature greater than 100° C., and at a pressure of at least 690 kPa, to produce a crude reaction product comprising the organohalosilane.
US10183953B2 Substituted 2-azabicycles and their use as orexin receptor modulators
The present invention is directed to compounds of Formula I: wherein X is N or CR1; Y is N or CR2; R1 is H, alkoxy, halo, triazolyl, pyrimidinyl, oxazolyl, isoxazole, oxadiazolyl, or pyrazolyl; R2 is H, alkyl, alkoxy, or halo; Z is NH or O; R3 is H, alkyl, alkoxy, halo, or triazolyl; R4 is H or alkyl; or R3 and R4, together with the atoms to which they are attached, form a 6-membered aryl ring or a 5- or 6-membered heteroaryl ring; R5 is pyridyl, pyrazinyl, or pyrimidinyl, wherein the pyridyl, pyrazinyl, or pyrimidinyl is optionally substituted with halo or alkyl; and n is 1 or 2. Methods of making the compounds of Formula I are also described. The invention also relates to pharmaceutical compositions comprising compounds of Formula I. Methods of using the compounds of the invention are also within the scope of the invention.
US10183952B2 Thienopyrroles as histone demethylase inhibitors
The present application relates to thienopyrrole derivatives, compounds of Formulas (I) and (Ia), wherein R, R1, R2 and R3 are as defined in the specification, pharmaceutical compositions containing such compounds and to their use in therapy. The compounds of the application can be useful for inhibiting KDM1 and the prevention and/or treatment of cancer, infectious disease, or a disease characterized by aberration of cellular energy metabolism, e.g., obesity.
US10183949B2 Pyrimidinone derivative having autotaxin-inhibitory activity
A compound according to any one of formula (Ia) to (Ic), or its pharmaceutically acceptable salt: wherein R1, R2, R3, R4a, R4c, R5 are as defined in the description.
US10183947B2 Pyrazole derivatives useful as 5-lipoxygenase activating protein (FLAP) inhibitors
The present application relates to novel compounds of formula (I) to their utility in treating and/or preventing clinical conditions including cardiovascular diseases (CVD), to methods for their therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds.
US10183945B2 Method of preparing AZA-pyridone compounds
Disclosed herein are methods for obtaining aza-pyridone compounds, which can be useful for ameliorating and/or treating a disease and/or a condition, including an orthomyxovirus infection.
US10183940B2 Aryl and heteroaryl-fused tetrahydro-1,4-oxazepine amides as somatostatin receptor subtype 4 (SSTR4) agonists
The invention relates to aryl and heteroaryl-fused tetrahydro-1,4-oxazepine amide derivatives of general formula (1), which are agonists of somatostatin receptor subtype 4 (SSTR4), useful for preventing or treating medical disorders related to SSTR4. In addition, the invention relates processes for manufacture of the compounds according to the invention.
US10183938B2 Geminal substituted quinuclidine amide compounds as agonists of α-7 nicotonic acetylcholine receptors
The present invention relates to novel geminal substituted quinuclidine amide compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of α7-nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.
US10183936B2 Hepatitis B core protein allosteric modulators
The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.
US10183933B2 Isoindolinone inhibitors of phosphatidylinositol 3-kinase
The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
US10183932B2 Substituted oxopyridine derivatives and use thereof cardiovascular disorders
The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
US10183930B2 Crystalline forms and processes for the preparation of cannabinoid receptor modulators
The present invention relates to crystalline forms of (1aS,5aS)-2-(4-oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid ((S)-1-hydroxymethyl-2,2-dimethyl-propyl)-amide (Compound 1) and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB2 receptor and are therefore useful in the treatment of CB2 receptor-mediated disorders, for example, osteoarthritis; pain; hyperalgesia; allodynia; inflammatory hyperalgesia; neuropathic hyperalgesia; acute nociception; osteoporosis; multiple sclerosis-associated spasticity; autoimmune disorders; allergic reactions; CNS inflammation for example; atherosclerosis; undesired immune cell activity, and inflammation associated with a disorder selected from: osteoarthritis, anaphylaxis, Behcet's disease, graft rejection, vasculitis, gout, spondylitis, viral disease, bacterial disease, lupus, inflammatory bowel disease, autoimmune hepatitis, and type 1 diabetes mellitus; age-related macular degeneration; cough; leukemia; lymphoma; CNS tumors; prostate cancer; Alzheimer's disease; stroke-induced damage; dementia; amyotrophic lateral sclerosis; and Parkinson's disease.
US10183925B2 Substituted naphtho[2,3-b]furans as water-soluble prodrugs for preventing and/or treating cancer
The present invention provides compounds represented by formula (1A), or pharmaceutically acceptable salts. Compounds represented by formula (1A), or pharmaceutically acceptable salts thereof, wherein A1 and A2 are identical or different, and each independently —C(═O) B, —C(═O)CR3AR3BB, —CO2B, —C(═S)OB, —CONR3CB, —C(═S)NR3CB, a hydrogen atom, or the like, wherein A1 and A2 are not both hydrogen atoms, wherein B is an optionally substituted 3- to 12-membered monocyclic or polycyclic heterocyclic group, an optionally substituted 3- to 12-membered cyclic amino group, or a group represented by the following formula (B), wherein the 3- to 12-membered monocyclic or polycyclic heterocyclic group and the 3- to 12-membered cyclic amino group have at least one or more secondary nitrogen atoms in the ring; R1 is a hydrogen atom or the like; R2A, R2B, R2C, and R2D are identical or different, and each independently a hydrogen atom or the like; and R8 is alkyl. wherein * denotes a bonding position.
US10183924B2 Sulfonylazide derivative for diene polymer
The present disclosure provides a composition. In an embodiment, a composition is provided and includes an ethylene/α-olefin/diene terpolymer and a polar component. The composition also includes a sulfonamide phthalic anhydride linkage (SPA) bonding the ethylene/α-olefin/diene terpolymer to the polar component.
US10183923B2 Method for synthesizing a precursor of a single dairy-lactone isomer
This disclosure provides a method for preparing a precursor of a single dairy-lactone isomer, methods of preparing a single dairy-lactone isomer, and to the organoleptic uses thereof.
US10183922B2 Methods and compositions for wound healing
The present invention relates to epoxy-tigliane compounds and their use in promoting wound healing. In particular embodiments, the epoxy-tigliane compounds are epoxy-tigliaen-3-one compounds. Methods of inducing or promoting wound healing as well as methods of reducing scarring and improving cosmetic outcomes upon healing of a wound are described. Compounds and compositions for use in wound healing are also described.
US10183919B2 Class of mu-opioid receptor agonists
The present invention provides a compound having the structure: or a pharmaceutically acceptable salt or ester thereof.
US10183916B2 Process for the preparation of triazines
The invention relates to an improved process for the manufacture of bis-resorcinyl triazines of formula (I) wherein R1 is a C1C18alkyl group or C2-C18alkenyl group as well as the respective alkyl substituted bis-resorcinyl derivatives of formula (II) wherein R1 is a C1-C18alkyl group or C2-C18alkenyl group and R2 and R3 are independently of each other a C1-C18alkyl group or a C2-C18alkenyl group.
US10183914B2 2-amino-5-keto-pyrimidine derivatives and the use thereof for controlling undesired plant growth
What are described are compounds of the general formula (I) and agrochemically acceptable salts thereof and the use thereof in the crop protection sector.
US10183907B2 Process for the synthesis of acrylic acid oligomers
A process for the synthesis of acrylic acid oligomer represented by formula (I): in which n is an integer ranging from 1 to 10, wherein the process comprises the step of heating acrylic acid at a temperature from 50° C. to 200° C. in the presence of a catalyst, water and at least one polymerization inhibitor. Formula (I) where n=0 is acrylic acid, the precursor for preparing the acrylic acid oligomer.
US10183903B2 Method for preparing 2,3,3,3-tetrafluoropropene using methyl magnesium chloride
The present invention discloses a method for preparing 2,3,3,3-tetrafluoropropene using methylmagnesium chloride, comprising the following steps: 1) preparing 1,1,2-trifluoropropene (CH3CF═CF2); 2) preparing 1,1,1,2,2-pentafluoropane (CF3CF2CH3); 3) preparing 2,3,3,3-tetrafluoropropene (CF3CF═CH2). In the present invention, using a Grignard reagent, namely methylmagnesium chloride, and tetrafluoroethylene as starting raw materials, 2,3,3,3-tetrafluoropropene is prepared by three steps of nucleophilic addition-elimination, fluorine addition, and dehydrofluorination in sequence. The process flow is relatively short, and the product yield is high.
US10183899B2 Normal alpha olefin synthesis using metathesis and dehydroformylation
The present invention discloses processes for producing normal alpha olefins, such as 1-hexene, 1-octene, and 1-decene, in a multistep synthesis scheme. Generally, a first normal alpha olefin is subjected to an olefin metathesis step to form a linear internal olefin, which is then subjected to an isomerization-hydroformylation step to form a linear aldehyde, which is then subjected to a dehydroformylation step to form a second normal alpha olefin.
US10183896B2 Antimicrobial glaze and porcelain enamel via double layer glaze with high zinc content
A cost-effective and practical antimicrobial glaze system and glazing process is disclosed herein. The antimicrobial glaze/enamel may comprise at least two layers: a base layer and a top layer. The base layer may contain a typical or normal glaze widely used in sanitary ware, having a low level of zinc oxide. The base layer glaze may be directly sprayed on the clay body surface. A thin top glaze layer is sprayed on top of the base glaze layer and the top layer may contain a high level of zinc oxide.
US10183890B2 Method of curing a gypsum calcination product
A method of conditioning stucco comprises the steps of supplying a quantity of stucco particles to a reaction vessel, the stucco particles comprising calcium sulphate hemihydrate and/or calcium sulphate anhydrite, as well as calcium sulphate dihydrate; and conditioning the stucco particles at a temperature of at least 100° C. and a humidity of at least 70%. During the step of conditioning the stucco particles, the bulk density of the stucco particles within the reaction vessel is at least 1 g/cm3.
US10183889B2 Glass having antiglare surface with low display sparkle
A glass article having a low level of grainy appearance that can appear to have a shift in the pattern of the grains with changing viewing angle of a display, or “sparkle.” The glass article—which, in some embodiments, is a transparent glass sheet—has small-angle-scattering properties and/or distinctness-of-reflected-image (DOI), leading to improved viewability in display applications, especially under high ambient lighting conditions. In some embodiments, the antiglare surface of the glass sheet is an etched surface, with no foreign coating present on the antiglare surface.
US10183888B2 Glass ceramic substrate made of a transparent, colored LAS glass ceramic and method for producing it
A glass ceramic substrate made of a transparent, colored LAS glass ceramic is provided. The glass ceramic has a gradient layer with keatite solid solution and an underlying core with high-quartz solid solution as predominant crystal phase. The keatite solid solution in a depth of 10 μm or greater exceeds 50% of the sum of the high-quartz solid solution proportion and keatite solid solution proportion. The ceramization includes a crystal transformation step, in which the high-quartz solid solution is transformed at a maximum temperature in the range of 910° to 980° and a time period of between 1 and 25 minutes in part into the keatite solid solution.
US10183885B2 Laser cut composite glass article and method of cutting
The present disclosure relates to a process for cutting and separating arbitrary shapes of thin substrates of transparent materials, particularly tailored composite fusion drawn glass sheets, and the disclosure also relates to a glass article prepared by the method. The developed laser method can be tailored for manual separation of the parts from the panel or full laser separation by thermally stressing the desired profile. The self-separation method involves the utilization of an ultra-short pulse laser that can be followed by a CO2 laser (coupled with high pressure air flow) for fully automated separation.
US10183884B2 Submerged combustion burners, submerged combustion glass melters including the burners, and methods of use
Submerged combustion burners having improved fuel and oxidant mixing characteristics. Submerged combustion melters including the burners. Methods of using submerged combustion melters to melt glass-forming materials and produce molten glass.
US10183882B1 System and method for pretreating turbid seawater
The system and method for pretreating turbid seawater utilizes polyelectrolyte dosing, clarification through a clarifier system and centrifugation in a decanter centrifuge followed by microfiltration to treat seawater prior to its injection through a desalination plant. The system for pretreating turbid seawater includes a static mixer for mixing a polyelectrolyte with a stream of turbid seawater to produce a polyelectrolyte-treated seawater mixture. At least one clarifier tank is in fluid communication with the static mixer for receiving the polyelectrolyte-treated seawater mixture and removing a first portion of solids therefrom to produce a clarified seawater mixture. A decanter centrifuge is in fluid communication with the at least one clarifier tank for receiving the clarified seawater mixture and removing a second portion of solids therefrom to produce centrifuged seawater. A microfiltration system is in fluid communication with the decanter centrifuge for receiving the centrifuged seawater to produce the pretreated seawater.
US10183881B1 Systems and methods for treating industrial feedwater
Feedwater is treated using a combination of techniques, including the integration of a brine solution to promote the formation of reactive and molecular species in the feedwater with electrolytic ionization, the application of electromagnetic fields and the application of plasma fields. The integrated, combined techniques offer an improved treatment of scale forming ions, bacteria and biological contaminants in feedwater.
US10183877B2 Sewage treatment chlorinator and system and method for use of same
A sewage treatment chlorinator for use at a site not connected to a municipal sewer system and system and method for use of the same are disclosed. In one embodiment of the sewage treatment chlorinator, a housing includes an external conduit coupled in a t-connection to a flow tube. An inner canister is sized to be selectively inserted and removed from the external conduit and includes a perforated end cap having a flow deck sized to suspend a chlorine tablet within a contact chamber of the flow tube. The flow tube receives effluent form an aerobic tank and discharge treated effluent to a post-treatment tank. At least a portion of the discharge from the flow tube is gravity-based discharge into the post-treatment tank.
US10183873B2 Water pretreatment unit using a fluorinated liquid
A unit for pretreating water by heat and/or ion treatment. It provides a pretreatment unit including a direct contact heat and/or ion exchanger having a continuous or dispersed phase that includes a fluorinated liquid that is not miscible with water with a density of more than 1.25.
US10183870B2 Point-of-use water treatment system
A water treatment system having a water treatment engine including a pressure vessel, electronics module and optionally replaceable shrouds. The water treatment engine may include a tether and a single connection point for water and power lines. The tether may have a release that is accessible only when the electronic module is removed. The water treatment engine may be circular and the water and power lines may be arranged within a region bounded by tangent lines that square the circular shape. The electronics module may be configured to receive one of a variety of alternative interchangeable displays. The electronics module may have a single display port that provides power and data that can be utilized by a plurality of different types of displays. The system may include a replaceable cartridge with soft end caps that include an integral seal and are shaped to self-center within the pressure vessel.
US10183868B2 Mesoporous zinc oxide powder and method for production thereof
A method of manufacturing a zinc oxide powder including synthesizing a mesoporous zinc oxide precursor powder by adding an aqueous solution of zinc chloride to an aqueous solution of sodium carbonate while agitating to cause precipitation of a mesoporous zinc carbonate powder wherein the molar ratio of zinc chloride to sodium carbonate present when the aqueous solution of zinc chloride and the aqueous solution of sodium carbonate are reacted is at least 1:2, heat treating a mesoporous zinc precursor material to form the mesoporous zinc oxide powder at a heat treatment temperature in the range of 250-575° C. The zinc oxide powder includes mesoporous zinc oxide aggregates with a plurality of primary zinc oxide crystallites bonded together at shared interfaces.
US10183866B2 Composition for forming conductive pattern and resin structure having conductive pattern
The present invention relates to a composition for forming a conductive pattern and a resin structure having a conductive pattern, wherein the composition makes it possible to form a fine conductive pattern on various polymer resin products or resin layers through a simple process, and can more effectively meet needs of the art, such as displaying various colors. The composition for forming a conductive pattern, comprises: a polymer resin; and a non-conductive metal compound having a predetermined chemical structure, and may be a composition for forming a conductive pattern through electromagnetic irradiation, by which a metal nucleus is formed from the non-conductive metal compound.
US10183863B2 Porous hollow shell WO3/WS2 nanomaterial and method of preparing same
Provided is a method for the preparation of a porous hollow shell WO3/WS2 nanomaterial, comprising: (1) adding a hexavalent tungsten salt to a sol A comprising mesocarbon microbeads, and stirring to obtain a sol B; (2) drying and grinding the sol B, and then heating a resulting powder at 200-500° C. for 0.5-2 hours to obtain a porous hollow shell WO3 nanocrystalline material; (3) placing the porous hollow shell WO3 nanocrystalline material obtained by Step 2 and a sulfur powder separately in a vacuum furnace, controlling such that a degree of vacuum is −0.01 to −0.1 MPa and a temperature is 200-500° C., and reacting for 0.5-3 hours to obtain a WO3/WS2 porous hollow shell nanocrystalline material. Also provided is a porous hollow shell WO3/WS2 nanocrystalline material obtained by the method.
US10183861B2 Laser reseal including a protective structure
A method for manufacturing a micromechanical component including a substrate and a cap connected to the substrate, the cap, together with the substrate, enclosing a first cavity, a first pressure prevailing and a first gas mixture having a first chemical composition being enclosed in the first cavity. An access opening connecting the first cavity to surroundings of the micromechanical component is formed in the substrate or in the cap. The first pressure and/or the first chemical composition is adjusted in the first cavity. The access opening is sealed by introducing energy or heat into an absorbing part of the substrate or of the cap with the aid of a laser. A layer for protecting the sealed access opening is applied to or deposited on or grown on a material area, which transitions into a liquid aggregate state and then transitions into a solid aggregate state and seals the access opening.
US10183856B2 Manufacturing method of micro-electro-mechanical systems device
A manufacturing method for a Micro-Electro-Mechanical Systems (MEMS) structure includes implementing a surface modification process, to form a transformation layer on the surfaces of the MEMS structure; implementing an anti-stiction coating pre-clean process, to clean the transformation layer on the surfaces towards a particular direction; and implementing an anti-stiction coating process, to coat a monolayer on the surfaces of the MEMS structure.
US10183849B2 Rope guidance for second device used on DuraHoist arm
A line guidance device (40) is provided for use with a confined space entry/retrieval hoist and fall protection anchorage system (10) and includes a line guide (46) that guides a line from an extend/retract line device (22) past another extend/retract line device (20) with both devices (20, 22) mounted on a backside (24) of a mast (12) of the system (10).
US10183847B2 Cylinder retention device
A system and method for retaining a linear actuator on a crane component such as a mast is disclosed. In the system a retaining mechanism is mounted on either a body of the linear actuator or the crane component and a catch is mounted to the other of the body or the crane component. Retraction of a rod of the linear actuator causes a cap on the rod to contact the retaining mechanism, which causes the retaining mechanism to move into a latched configuration securing the linear actuator.
US10183843B2 Monitoring of step rollers and maintenance mechanics of passenger conveyors
The present invention relates to step roller monitoring and maintenance personnel monitoring of a passenger conveyor, and belongs to the field of passenger conveyor technologies. In the monitoring system and monitoring method of the present invention, an imaging sensor and/or a depth sensing sensor is used to sense the step roller/maintenance personnel of the passenger conveyor to acquire data frames, and the data frames are analyzed and processed to monitor whether the movement or position of the step roller/activity or position of the maintenance personnel is in a normal state.
US10183840B2 System for chain chordal action suppression
A vertical lift conveyor for lifting materials between different vertical levels. The vertical lift conveyor includes a pair of spaced uprights and a carriage that moves vertically along the spaced uprights. The vertical lift conveyor includes a drive assembly including a drive motor coupled to a drive shaft. Each end of the drive shaft includes a first sprocket and a second sprocket that each engages one of a pair of lift chains. The first and second sprockets each include a plurality of teeth (N). The first and second sprockets are offset from each other 180/N°. The offset between the first and sprockets creates sinusoidal velocity profiles for the two chains that are out of phase with each other. A connection block is used to connect the pair of lift chains to each side of the carriage combines the lift chain velocities into a linear vertical velocity for the carriage.
US10183837B2 Communication method for an elevator system between a unit on an elevator car and a remote service center
A method for the exchange of data between one unit of an elevator system and a monitoring unit of a service center locationally remote from the elevator system, wherein, via a first communication network, the one unit is connected with a communication unit arranged on, or in, an elevator car that travels vertically in an elevator hoistway, and wherein the data that are transmitted by the one unit are transmitted to the communication unit and stored there. A mobile-communication end-device brought into the elevator car by an elevator passenger is connected, via a second wireless communication network, with the communication unit and the stored data are transmitted by the communication unit to the end-device, and stored in the latter. When the elevator car is exited by the elevator passenger with the end-device, the stored data are transmitted from the end-device via a public mobile-communication network to the monitoring unit.
US10183836B2 Allocating destination calls using genetic algorithm employing chromosomes
A method of assigning destination call in an elevator group forms chromosomes including genes where each gene is a correlation of a call and an elevator trip, the possible round trips are calculated, each round trip is evaluated for optimization procedure. The calls are assigned to the elevators by the destination call control based on the best chromosome determined.
US10183835B2 Image forming apparatus
An image forming apparatus includes: one paper cassette configured to accommodate a paper sheet; an image forming section provided above the paper cassette to form an image on the paper sheet; a main conveying path configured to convey the paper sheet; and a reverse conveying path configured to reverse the paper sheet, wherein the reverse conveying path includes: a first reverse conveying path provided side by side with the paper cassette to extend vertically; a second reverse conveying path configured to connect from the first reverse conveying path and extend below the paper cassette; a guide plate configured to open and close the first reverse conveying path and release pressure of a pair of paper conveying rollers; and an entry restricting unit provided at a boundary point between the first reverse conveying path and the second reverse conveying path to open and close a conveying course of the paper sheet.
US10183831B1 Post-processing apparatus
In accordance with an embodiment, a post-processing apparatus comprises a knocking section, a receiving section, a driving section and a pressing section. The knocking section knocks a staple in a sheet. The receiving section faces the knocking section. The receiving section receives the sheet in which the staple is knocked from the knocking section. The driving section can change an interval between the knocking section and the receiving section in an opposite direction in which the knocking section and the receiving section face each other. The pressing section extends continuously in a sheet width direction. The pressing section presses the sheet before the staple is knocked in the sheet.
US10183829B2 Sheet stacking apparatus and image forming apparatus
A sheet stacking apparatus includes a discharging portion including a nip portion nipping and conveying a sheet, a stacking portion on which the sheet discharged by the discharging portion is stacked, an air blowing unit configured to blow air toward a lower face of the sheet being discharged by the discharging portion, and an air volume control portion configured to control the air blowing unit such that a volume of the air blown by the air blowing unit is switched from a first air volume to a second air volume which is smaller than the first air volume while the nip portion of the discharging portion is nipping and conveying the sheet to set the volume of the air to the second air volume in a case where a trailing end of the sheet discharged by the discharging portion passes through the nip portion.
US10183825B2 Winding method
A winding method includes rotating a winding drum; transferring a first web structure from a first lay down station to the web stabilizing bed of a first winding station; cutting the web structure; contacting the web structure with a web assembly hold down element, winding the web structure into a roll assembly; and discharging the roll assembly from the winding drum.
US10183824B2 Sheet feeding apparatus, image reading apparatus and image forming apparatus with sheet feeding apparatus
A sheet feeding apparatus includes a feeding rotating member to feed a sheet, and a separating portion to separate and feed one by one the sheet fed by the feeding rotating member. The separating portion includes a separating rotating member to feed a sheet and a separating member to form a separation nip portion by abutting on the separating rotating member. In addition, a sheet stacking portion on which sheets are stacked is disposed to face the feeding rotating member, and a sheet introducing portion guides the sheet toward the separating portion. The sheet introducing portion being is in a downstream side of the sheet stacking portion and positioned above a tangent line at a contacting point between the feeding rotating member and the sheet stacking portion in a vertical direction. A gap portion is disposed on the sheet introducing portion and outside of the feeding rotating member in a sheet width direction perpendicular to a sheet feeding direction and curves the sheet fed by the feeding rotating member in the sheet width direction.
US10183823B2 Lift mechanisms
In an example, a lift mechanism may include a linkage to engage with a pick arm, a crank switchably disposed in a first position and a second position, and a swingarm to move the crank from the first position to the second position. The linkage may move the pick arm from a raised position to a lowered position when the crank moves from the first position to the second position.
US10183819B2 Assembly for printer having damped media tray
An assembly of a device having a component, the assembly including a damper having a damper gearwheel coupled to a damper member. The damper member has a first condition restricting motion of the component of the device to a first rate in a first direction and a second condition restricting motion of the component of the device to a second rate in the first direction slower than the first rate. The damper gearwheel is rotationally fixed relative to the damper member when the damper is in the first condition. The damper gearwheel is rotatable relative to the damper member when the damper is in the second condition.
US10183816B2 Apparatus for picking and placing a plate-like product
An apparatus for picking and placing a plate-like product comprises: a base; at least two guide rods disposed on said base vertically; a picking and placing device mounted on each of said guide rods vertically slidably, the picking and placing device is telescopic in a horizontal direction to smoothly and steadily pick and place the plate-like product; a driving device disposed on said base, said driving device connects with said picking and placing device for driving said pick and place device to slide along the respective guide rods.
US10183809B2 Pin retention for conveyor modules
A conveyor module includes a module body with a pair of first link ends extending in a first direction of travel and a second link end extending in a second direction of travel opposite the first direction. Each of the first and link ends has a transverse opening therethrough. At least one of the first link ends has a first mating portion. A pin is configured to be received in the first transverse openings of the module body. The pin has a shaft and a lever affixed at a first end of the shaft. The lever has a second mating portion configured to be rotatably coupled with the first mating portion of the module body, thereby preventing transverse movement of the shaft.
US10183807B2 Cambelt, in particular a cambelt suitable for agricultural machinery
Cam belt, particularly for agricultural machinery, produced from a polymer provided with reinforcement inserts, has cams on the inner side of the cam belt that are used to drive cam belt. A first flank faces in the running direction of cam belt and a second flank faces in opposite direction. Cams are spaced apart from one another by gaps in a predefined division, and gaps are delimited by first flank and second flank of two adjoining cams and a base which connects two flanks. During operation of cam belt carrier of a cam wheel resting against second flank of one of adjoining cams and against the base of a gap engage with the gaps. On outer side of belt, functional elements are fixed by a fastener which from inner side of the belt passes through the cam belt and the functional elements via at least one through hole.
US10183804B2 Tank trailer having integrated heat panels
A temperature-controlled tank body having an integrated heat transfer panel is disclosed. The tank body may be mounted to a truck, trailer, or other mobile equipment and used for transporting a fluid at a temperature that is greater than that of the ambient environment. In an illustrative embodiment, the tank includes a barrel segment having a first sheet and an adjacent second sheet. The first sheet is joined to the second sheet along a first edge and a second, opposing edge. The first sheet is also joined to the second sheet at a plurality of locations between the first edge and second, opposing edge and enclosed at the ends to form a fluidly-sealed area. The tank includes a fluid inlet to facilitate pressurization of the fluidly-sealed area to generate a hydroformed cavity between the first sheet and the second sheet.
US10183800B2 Container for delivering a prefixed number of products at a time and a process for making of said container
A container for delivering a predetermined number of products at a time includes a compartment defining an inner volume and configured to house multiple products, a passageway having an outlet configured to enable the delivery of the multiple products outside of the container, a door defining an opening configured to put the compartment in communication with the passageway, and a delivery mechanism arranged at the door and configured to manage passage of the multiple products through the door. The delivery mechanism is configured to be placed in a closing condition in which the delivery mechanism prevents passage of the multiple products through the door, and the delivery mechanism is further configured to be placed in a passage condition in which the delivery mechanism allows passage of one or more products of the multiple products through the door, thus allowing the one or more products to exit the compartment.
US10183799B1 Beverage container insulator
A beverage container insulator can include a body defining a cylinder with an opening at a first end and a web closing a second end. An interior surface defined by the body can receive a beverage container. An exterior surface is defined by the body opposite to the interior surface. The beverage container insulator can also include a first pattern of indicia positioned on the exterior surface. The first pattern forms readable text oriented such that a bottom edge of the readable text positioned closer to the web than the opening. The beverage container insulator can also include a second pattern of indicia positioned on the interior surface. The second pattern forms readable text oriented such that a bottom edge of the readable text is positioned closer to the opening than the web.
US10183794B2 Use of a water-soluble unit dose article to improve the user dosing experience
The present invention relates to the use of water-soluble unit dose article to improve the user dosing experience.
US10183791B2 Cap for a container
A cap for a container comprising a ferrule to be fixedly attached to the neck of the container, the ferrule comprising an upper wall and a tubular skirt extending downwardly from the upper wall; a tamper evidence mechanism connected with the ferrule; an overseal button removably arranged on top of the upper wall of the ferrule so as to at least fully cover the tamper evidence mechanism, the overseal button being connected to the tamper evidence mechanism such that upon first removal of the overseal button the tamper evidence mechanism is irreversibly damaged. The overseal button comprises at least one translucent portion arranged to extend over the at least one portion of the tamper evidence mechanism which is irreversibly damaged upon first removal of the overseal button.
US10183782B2 Bottom-handled bag having integral ergonomic handle formed from deflected weld line
A handle body is formed in a lower end of a bag between a transverse bottom seal and an intermediate handle seal. The handle body has a deflected weld line having a midpoint and end points, and is nearest to the transverse bottom seal at the midpoint. The deflected weld line is arranged so that a line tangent to the deflected weld line at either end point defines an angle greater than or less than 90 degrees with respect to a second line running transversely through the midpoint. Between the midpoint and the end points, the deflected weld line can include different combinations of perforated, nonperforated, welded, and nonwelded line segments.
US10183781B2 Fireproof envelope assembly
A fireproof envelope assembly for protecting a flammable object from fire damage includes an envelope that contains a flammable object. The envelope is comprised of a fire resistant material to inhibit the flammable object from being damaged by fire.
US10183773B2 Easy thread carriage for stretch film wrapping system
A stretch film wrapping machine includes a wrap location and a film carriage that is movable during wrap operations. The film carriage includes a first driven roller, a second driven roller and a drive a drive arrangement for the driven rollers. The carriage includes a primary frame part and a secondary frame part. A film path runs between the primary frame part and the secondary frame part and passes between the driven rollers. The secondary frame part moves relative to the primary frame part between an open position for film threading and a closed position for operation. The second driven roller is mounted to the secondary frame part for movement therewith and has a driven gear that engages with a drive gear of the drive arrangement when the secondary frame part is in the closed position. In the open position the driven gear dis-engages from the drive gear.
US10183769B2 Sealing tool for strap
A tool for sealing overlying courses of a strap that includes a gripping unit, a power supply unit detachably affixed to one end of the gripping unit, and a motor in the gripping unit. A cam is coupled to the motor and a notching unit is coupled to the cam by a plurality of linkages.
US10183768B2 Pallet threading apparatus
A pallet threading apparatus including a directional handle; a flexible rod having a first end and a second end; a football shaped head member having a top portion and bottom portion, the top portion including a longitudinal slot; the directional handle is attached to the first end and the football shaped head member is attached to the second end; a cleat element positioned in the longitudinal slot, the cleat element including a pair of side walls having a plurality of oppositely opposed teeth for retaining a section of strapping material.
US10183767B2 Box spring packaging method and apparatus
Improved packaging materials for packaging multiple mattress spring cores together in a compressed stack, wherein the two ends of the stack are covered by end panels comprising a laminated paper stack panel that includes one or more layers of a stretchable paper called extensible kraft paper laminated together with a water soluble glue. The mattress spring cores are separated by an interleaving sheet comprising one layer of extensible kraft paper.
US10183763B2 Dual-sloping carousel
A dual-sloping carousel is disclosed. According to the present invention, the carousel comprises forward-sloping and reverse-sloping sections, so as to reduce the risk of falling baggage, thereby preventing the baggage from being damaged.
US10183762B2 Stop device and aerial vehicle using the same
A stop device includes a motor rotor assembly including a rotating shaft, a first shift lever fixedly connected to the rotating shaft and including a first shifting part configured to rotate around an axis of the rotating shaft to form a first motion trajectory, and a second shift lever rotatably connected to the first shift lever and including a second shifting part partially within the first motion trajectory. The first shifting part is configured to drive the second shifting part to rotate around the axis of the rotating shaft to form a second motion trajectory. The stop device further includes a motor stator assembly sleeved on the rotating shaft and rotatably connected with the rotating shaft. The motor stator assembly includes a stopping boss located on a periphery of the first motion trajectory and partially within the second motion trajectory.
US10183759B2 Adjustable engine suspension for positioning the engine relative to the mount thereof
The invention relates to a method for mounting an engine module (1) in a support comprising a first structure (3) and a second structure (2) that is offset relative to the first structure (3), method intended for positioning at least a specified part (4) of the engine module (1) relative to an element (6) of the second structure (2) by means of an isostatic suspension connecting the engine module (1) to said first structure (3) by means of first connecting rods (10a, 10b, 10c, 10d) and to said second structure (2) by means of second connecting rods (10e, 10f), the length of said first and second connecting rods being defined in advance, method wherein the length of at least two (10c, 10f) of said first and second connecting rods is adjusted relative to the previously defined length thereof, in order to position said specified part (4) of the engine module (1) relative to said element (6) of the second structure (2) in said support. The invention also relates to said support comprising adjustable connecting rods, in an installation comprising in particular an auxiliary power unit for an aircraft.
US10183757B2 Aircraft with a wing tip comprising a fuel pod
An aircraft comprising a wing, the wing having a connection interface at the tip of the wing, and the wing being interchangeable between a first configuration in which a first wing tip is connected to the connection interface, and a second configuration in which a second wing tip is connected to the connection interface to replace the first wing tip. The second wing tip comprises a fuel pod for carrying additional fuel, and a wing tip device for improving aerodynamic efficiency. The wing may be designed for performance in both configurations.
US10183756B2 Aircraft engine mount comprising at least one transverse nut and aircraft comprising the said engine mount
An aircraft engine mount which comprises first and second parts connected by connecting elements and wherein one of the two connected parts comprises at least one transverse hole opening onto an access face of the part and into which there open at least two passage holes each intended to house a threaded shank of one of the connecting elements. The engine mount comprises a transverse nut which comprises at least two bodies joined together each having a tapped hole configured to engage with one of the threaded shanks.
US10183754B1 Three dimensional graphene foam reinforced composite coating and deicing systems therefrom
An efficient deicing system is a silicone-graphene foam composite connected to a source of electrical energy for current promoted heating of the silicone-graphene foam composite. The deicing system can be constructed by infusion and curing a silicone resin infused into the graphene foam attached to electrical contacts. The deicing system can be attached to surfaces of an aircraft for rapid deicing of the aircraft.
US10183751B2 Side-facing belted aircraft seats
Side-facing belted aircraft seats include a tactile signaling unit to induce movement of the seat occupant. For such purpose, the signaling unit may be provided with a signaling lid covering a female buckle of a lap belt restraint assembly. The signaling lid is moveable between a closed position wherein engagement of a male tab of the lap belt with the female buckle is precluded and an open position wherein engagement of the male tab with the female buckle is allowed. The signaling lid thereby provides tactile stimulation when in the open position thereof to induce the seated occupant to shift on the cushioned seat so that a midsaggital plane of the occupant is aligned with an offset plane of the seat that is offset by a predetermined distance toward one side of the seat relative to a midplane of the seat.
US10183748B2 Drone device security system for protecting a package
A fact checking system utilizes social networking information and analyzes and determines the factual accuracy of information and/or characterizes the information by comparing the information with source information. The social networking fact checking system automatically monitors information, processes the information, fact checks the information and/or provides a status of the information, including automatically modifying a web page to include the fact check results. The fact checking system is able to be implemented utilizing a drone device. The drone device is able to be implemented in conjunction with a security system.
US10183744B2 Magnetic orientation detent
In one embodiment, a hybrid aircraft includes a fixed-wing propulsion system and a multirotor propulsion system. The multirotor propulsion system includes a propeller coupled to a motor shaft. A motor drives the propeller via the motor shaft. The hybrid aircraft further includes a magnetic orientation detent to prevent the propeller of the multirotor propulsion system from rotating when power to the multirotor propulsion system is removed. The magnetic orientation detent further includes a plurality of magnets coupled to the circumference of the motor shaft and a detent magnet magnetically coupled to the plurality of magnets.
US10183743B2 Method and apparatus for aircraft sensor and actuator failure protection using reconfigurable flight control laws
A method and apparatus for reconfiguring flight control of an aircraft during a failure while the aircraft is flying. The method and apparatus provide a control law that is software-implemented and configured to automatically send flight control data to a mixing/mapping matrix. The method and apparatus also provide a reconfiguration management tool configured to communicate with the mixing/mapping matrix in order to safely transfer authority from a failed actuator to a back-up actuator. The method and apparatus also provide a sensor management tool for providing input to the reconfiguration management tool in order to smooth any transient conditions that may occur during reconfiguration. The method and apparatus provide for a way of smoothing any possible transient situation that might otherwise occur by employment of a fader, the fader being used to gradually convert positioning of failed actuators and positioning of reconfigured actuators. An exemplary aircraft for using the method and apparatus of a reconfigurable flight control system is a quad tilt rotor. The quad tilt rotor provides a variety of redundant and back-actuators, as such, having a robust and highly qualified reconfigurable flight control system is very desirable.
US10183742B2 Direct orientation vector rotor
A direct orientation vector rotor (DOVER) for use on rotary wing aircraft includes a gear set for multidirectional rotor orientation based on the spherical coordinate system; an inclination mechanism, wherein the rotor is moved from the 0° horizontal position to an inclined position; a rotational turret, wherein the rotor is moved along the azimuth and wherein the inclination mechanism is housed; and a motion-adapted gear lubrication housing.
US10183741B2 Multicopter-assisted system and method for launching and retrieving a fixed-wing aircraft
The present disclosure provides various embodiments of a multicopter-assisted launch and retrieval system generally including: (1) a multi-rotor modular multicopter attachable to (and detachable from) a fixed-wing aircraft to facilitate launch of the fixed-wing aircraft into wing-borne flight; (2) a storage and launch system usable to store the modular multicopter and to facilitate launch of the fixed-wing aircraft into wing-borne flight; and (3) an anchor system usable (along with the multicopter and a flexible capture member) to retrieve the fixed-wing aircraft from wing-borne flight.
US10183740B2 Leading edge nose structure on the vertical stabilizer of an aircraft
An aircraft with a fuselage, wings, horizontal stabilizers and a vertical stabilizer, wherein on a front portion of the vertical stabilizer an elongated one-piece nose element is mounted which forms lateral air guide surfaces. To the front end of the nose element a perforated metal plate nose member is attached. The front end of the nose element being closed and between this closed front end and the nose member an elongated air channel is formed.
US10183736B2 Ventilated aero-structures, aircraft, and associated methods
Ventilated aero-structures include a micro-lattice structure operatively coupled to a honeycomb core. The interface between the honeycomb core and the micro-lattice structure is configured to permit air flow to and from the honeycomb core via the micro-lattice structure. Aircraft include a ventilated aero-structure and a ventilation system configured to circulate air through the ventilated aero-structure. Some methods include coupling a micro-lattice structure to a honeycomb core. Some methods include utilizing a ventilated aero-structure to assemble an aircraft.
US10183735B2 Window frame assembly for aircraft
A window frame assembly for an aircraft, includes a window frame of composite material, adapted for attachment in a window opening of an aircraft, having an outer flange with an exterior surface and an interior surface, a metal erosion shield attached to the exterior surface of the outer flange, and a polymer adapter ring, attached to the interior surface of the outer flange. The window frame has a substantially constant thickness, and the erosion shield has a substantially constant cross-sectional shape. The adapter ring has a sloped engagement surface configured for supporting a window pane assembly.
US10183727B1 In-situ turret bearing repair and assembly
In an offshore system having a floating vessel, a turret within a hull opening, and a bearing assembly including a support row assembly axially transferring the weight of the turret to the vessel and allowing the vessel to weather vane about the turret, a method and arrangement for in situ remediation of a damaged support row assembly. An outer upper ring is removed from an outer lower ring and a support ring is installed on the outer lower ring. A lower race and support rollers of a remedial support row assembly are installed on the support ring. A reaction ring is positioned above the support ring and connected to an inner ring secured to the turret. The inner ring is axially displaced relative to the outer lower ring and the turret axial loading is transferred to the remedial support row assembly between the support ring and the reaction ring.
US10183721B2 Bicycle control device
A bicycle control device is basically provided with a mounting bracket, a hydraulic unit and a shift unit. The mounting bracket includes a handlebar clamp defining a handlebar mounting axis. The hydraulic unit is provided on the mounting bracket and includes a cylinder housing defining a cylinder bore, a hydraulic reservoir and a piston. The hydraulic reservoir is fluidly connected to the cylinder bore. The piston is movably disposed in the cylinder bore along a cylinder axis of the cylinder bore. The shift unit is provided on the mounting bracket and includes a wire take-up member pivotable about a take-up axis. The wire take-up member of the shift unit and the hydraulic reservoir are disposed between the handlebar mounting axis and the cylinder axis as viewed along a first direction parallel to the take-up axis of the wire take-up member.
US10183720B2 Engine support structure for saddled vehicle
An engine support structure for a saddled vehicle inhibits transmission of engine vibration to a vehicle body frame and keeps rigidity of the vehicle body frame. The engine support structure for a saddled vehicle includes a pair of mounted portions (21) provided integrally with an engine (E) and disposed at lateral ends in a vehicle width direction of the engine (E), a pair of engine supporting brackets (27) disposed at lateral ends in the vehicle width direction of a vehicle body frame (1) and extending to the mounted portions (21), respectively, and engine mounting portions (31) provided at the brackets (27), respectively, in which each of the mounted portions (21) is mounted to a corresponding one of the engine mounting portions (31) with at least one damper member (51) provided therebetween to be independently elastically displaceable.
US10183719B2 Passenger trailer apparatus
A passenger trailer apparatus for towing a passenger behind a mobility scooter is provided. The mobility scooter has a tow bar or hitch. The passenger trailer apparatus comprises a trailer frame and an axle mounted to and through the trailer frame. A tire is rotatably, releasably mounted to each end of the axle. The platform has a top surface and a bottom surface with the bottom surface of the platform mounted to the trailer frame. A chair assembly is mounted to the top surface of the platform with the chair assembly sized and shaped for receiving a passenger. A receiver bar having a first end and a second end is provided. The first end of the receiver bar is connected to the platform and the second end of the receiver bar capable of being releasably connected to the tow bar or hitch of the mobility scooter. The passenger trailer apparatus provides secure, reliable performance, quick assembly and breakdown, and easy transport and storage.
US10183718B2 Modular frame for stand-up, motor-driven scooter
This design incorporates four separate modules which are bolted together in this succession: a welded, structural single-unit steering tube/downtube module; independent, twin, front-to-rear horizontal frame rails which serve as the support for the rider to stand; a welded, structural single-unit module to mount shock absorbers and a swingarm; and, a welded swingarm. The defined space between the twin frame rails and the two adjoining modules can be modified by altering the length of the frame rails and/or using spacers between each rail and its corresponding module at the bolt-on location.
US10183716B2 Seat connecting device
A seat connecting device includes a first base unit for coupling with a bicycle seat and a second base unit. The first base unit includes an extension having a first end portion with first teeth and a connecting portion. The second base unit includes a body and a connecting member. The body includes a second end portion with second teeth and a sliding groove extending through the second end portion. The connecting member extends through the sliding groove and is detachably connected to the connecting portion. The connecting member selectively presses against a side of the second end portion distant to the second teeth. The second teeth disengageably engages with the first teeth. A water bottle holder can be mounted to the body.
US10183712B2 Walking control method, walking control program and biped walking robot
Provided is a walking control method enabling stable walking operation to be realized, a walking control program and a biped walking robot. A walking control method includes, during walking operation of a biped walking robot having a position of center of gravity being adjusted at a predetermined reference angle that enables the robot to be upright, a step of acquiring information indicative of an inclination angle of an upper body relative to the reference angle, and a step of operating, with one of a first leg and a second leg not being grounded due to the walking operation, the first leg and the second leg such that the upper body is maintained within a predetermined angle range relative to the reference angle according to the inclination angle.
US10183710B2 Combination of a drive wheel and a gearbox for a continuous track system
Combination of a drive wheel and a gearbox for a continuous track system, the gearbox (1) comprising an annular input member (2) for connection to an end part (14) of a drive axle input member (16) and an annular output member (4) connected to the drive wheel (3), the annular input member (2) and annular output member (4) being coaxially arranged with respect to a longitudinal axis (6) of the gearbox (1). The combination further comprises an annular transmission unit (8) coaxially arranged with respect to the longitudinal axis (6) of the gearbox (1) and connecting the annular input member (2) and annular output member (4) through a gear ratio (R) of less than one, the gear ratio (R) being a ratio of an angular input velocity of the annular input member (2) to an angular output velocity of the annular output member (4).
US10183709B2 Crawler with wear limit indicator
A crawler with a wear limit indicator comprises a crawler main body, sprocket holes formed to pass through a central portion of the crawler main body at equal intervals, core metals configured to be inserted and installed in-between the sprocket holes, left lugs configured to protrude from one surface of the crawler main body and simultaneously overlap with the sprocket holes and one of the core metals, right lugs configured to protrude from the other surface of the crawler main body and simultaneously overlap a pair of adjacent core metals, and a wear limit indicator configured to protrude from front and rear surfaces of the left lugs and the right lugs and inform that a replacement time for a crawler has come when worn-out surfaces of the left lugs and the right lugs are placed on the same horizontal plane as the wear limit indicator.
US10183706B2 Nodes for frame structures
A node for interconnecting frame members of a frame, the node including a single piece node body. A plurality of cup-shaped node connectors are disposed on the node body. Each of the plurality of node connectors include a closed end attached to the node body and an open end opposite the closed end and extending away from the node body. A sidewall extends between and connects the closed end to the open end. A tenon is formed on the open end. The tenon is shaped and sized to fit within a frame member. A transition is formed between the sidewall and the tenon defining a peripheral, radially outwardly facing groove in cooperation with the frame member, the groove shaped and sized to receive a weld.
US10183703B2 Conformable mud flap
A mud flap assembly includes a flexible elongated spine to which protective scales are permanently or removable attached in a spaced apart array with an overlapping configuration. An attachment, such as an adhesive, magnets, or weatherstrip is fixed to the spine. The attachment secures the spine to a flange or edge of a fender of a vehicle.
US10183702B2 Sidewall assembly for trailers
A sidewall assembly for a trailer including: a plurality of composite sandwich panels; and at least one composite side post coupled to the plurality of composite sandwich panels, each of the at least one composite side post including an outer post and an inner logistics post coupled to the outer post, wherein the outer post is formed with flexible metallic material and the inner logistics post is formed with hard metallic material.
US10183696B2 Methods and systems for controlling steering systems of vehicles
Methods and systems are provided for controlling a steering system of a vehicle is provided. A detection unit is configured to obtain a compass heading, a global positioning system (GPS) heading, or both. A processor is coupled to the detection unit, and is configured to determine whether a vehicle is on a straight line path using the compass heading, the GPS heading, or both, and to selectively implement a feature of the steering system based on whether it is determined that the vehicle is not on a straight line path.
US10183695B2 Method for calculating, in real time, the absolute position of a power steering member with improved accuracy
The present invention concerns a method for determining the position of a movable steering member (1, 2, 3) belonging to a steering mechanism (4) of a vehicle that comprises at least a first movable member (1), such as a shaft (1) of an assistance motor (M), and a second movable member (2), such as a rack (2), which cooperate with each other by means of at least one first link (L1), said method comprising a step (a) that involves measuring the position (θ1) of the first member (1), then a step (b) that involves calculating the instantaneous position (θ2) of the second member (2) from said position of the first member (θ1), and a correction step (d) during which the calculation of the position (θ2) of the second member (2) is adapted, taking into consideration the offset (δθυ) in the position of the second member (2) that results from the elastic deformation of the first link (L1) under the force (C1) transmitted by the latter.
US10183693B2 Electric power steering device
A slide member (26) is externally fitted to an outer peripheral surface of an outer ring (20) configuring a tip side bearing (9a) for supporting a tip portion of a worm shaft (6a) so as to be displaceable in an axial direction. A first inclined cylindrical face portion (32) which is an inclined surface disposed on an outer peripheral surface of the slide member (26), and a second inclined cylindrical face portion (30) which is an inclined surface disposed on an inner peripheral surface of a guide member (28) internally fitted and fixed to a holding hole (10a) of a housing (3a) are fitted to each other so as to be slidable in an inclined direction of the respective inclined cylindrical face portions (32, 30). An elastic ring (29) which biases a bearing holding member (26) against to one side in the axial direction is disposed. This realizes a structure which can shorten an axial dimension of a tip side portion of the worm shaft in an electric power steering device including biasing means for minimizing backlash in a meshing portion of a worm reduction gear.
US10183691B2 Torque transmission joint and electric power steering system
A torque transmission joint transmits torque between a drive shaft and a driven shaft. The torque transmission joint includes: a coupling including: a first concave-convex portion which is provided on one of inner and outer circumferential surfaces thereof and is engaged with a drive-side concave-convex portion of the drive shaft with a gap; and a second concave-convex portion which is provided on the other of the inner and outer circumferential surfaces and is engaged with a driven-side concave-convex portion of the driven shaft with a gap; a drive-side elastic member which is provided between the drive shaft and the coupling to be torque-transmittable; and a driven-side elastic member which is provided between the coupling and the driven shaft to be torque-transmittable. A concave-convex shape of the first concave-convex portion and a concave-convex shape of the second concave-convex portion are different from each other.
US10183689B2 Steering column apparatus
Disclosed is a steering column apparatus including an impact energy absorbing mechanism for absorbing an impact energy at a secondary collision. The impact energy absorbing mechanism includes an energy absorbing section that serves as a load generating section for absorbing the impact energy. The energy absorbing section includes (a) a resistive member that extends along an axial direction of the middle jacket and is fixed to the middle jacket and (b) a wire having a bent portion that is wound around the resistive member to have a curvature and a front portion that is fixed to the upper jacket, the front portion being at a more forward position than the bent portion.
US10183688B2 Adjustment lever assembly, and position adjustment device for steering wheel
Drive-side engagement protrusions (66, 66) formed on the outer surface of a drive-side cam (29a) are press-fitted in engagement cutouts (75, 75) formed in a second joining section (70) of an adjustment lever (23a), and a fitting hole (74) formed in the second joining section (70) of the adjustment lever (23a) is fitted over and affixed, by interference fit, to the portion of a rod-like member (17a), which is located near one end thereof in the axial direction. As a result, the adjustment lever (23a), the drive-side cam (29a), and the rod-like member (17a) are joined so as to be rotatable together. The provided structure can prevent the adjustment lever from rocking and rattling even in an unlocked state.
US10183687B2 Pushcart
A pushcart includes a steering unit, a main wheel, a dolly portion, an auxiliary wheel, a connecting unit, a slope angle sensor, a gyrosensor, and a case. On one end of the steering unit, there is provided a cylinder-shaped hinge unit that is supported in a rotatable manner at the other end of the connecting unit on the opposite side to the main wheels, and a holding portion is provided on the other end of the steering unit. A controller performs inverted pendulum control in which the main wheels are rotated based on the detection results of the gyrosensor and the slope angle sensor.
US10183685B2 Virtual omnimover
A ride control system for controlling a plurality of vehicles on a path includes a path processor and a bi-directional voting circuit in circuit with the path processor. Each vehicle of the plurality of vehicles may include a vehicle processor supported by the at least one vehicle and shunt relays in circuit with the at least one vehicle processor. Each vehicle processor may be configured to close a respective shunt relay upon a predetermined condition of the vehicle whereby the bi-directional voting circuit is activated to notify all other vehicles.
US10183684B2 Multiple vehicle control system
A system includes an energy management system disposed onboard a vehicle system configured to travel on a route during a trip. The energy management system is configured to receive trip information from a second vehicle system that includes one or more constraints including at least one of speed, distance, or time restrictions for the vehicle system along the route. The energy management system is further configured to generate a trip plan for controlling movement of the vehicle system along the route during the trip. The trip plan is generated based on the one or more constraints. The trip plan has a plan speed profile that designates speeds for the vehicle system according to at least one of distance or time during the trip. The energy management system is further configured to control movement of the vehicle system during the trip according to the plan speed profile of the trip plan.
US10183682B2 Method of converting a bi-level auto-rack railcar
A method of shipping automobiles, railcars for shipping automobiles, and methods of manufacturing railcars for shipping automobiles to enable more efficient shipping of automobiles by facilitating conversion of autorack cars between unilevel, bi-level and tri-level configurations, and/or by providing increased load factors.
US10183679B2 Apparatus, system and method for personalized settings for driver assistance systems
A system, apparatus and method for controlling operation of a vehicle. Driver assistance system (DAS) data may be used for controlling one or more function of the vehicle via a driver assistance system. Driver profile data (DPD) is generated and/or received that includes training data from sensor monitoring of a driver's usage characteristics for at least one feature of a vehicle type during a driver-controlled mode of vehicle driving. The DPD is processed with the DAS data to determine if the DPD conform to one or more safety metrics. A driver profile data file may be created by weighing the portions of the DAS data with the DPD that do not conform with the safety metrics. One or more functions on the vehicle may be controlled via the driver profile data file using the driver assistance system during one of a semi-autonomous and fully autonomous mode of operation.
US10183673B2 Powertrain operation and regulation
One or more powertrains can include a motor-generator disposed therein that is electrically coupled to an energy storage device through an inverter gate. A regulation strategy can monitor operation of the powertrain to regulate the inverter gate to selectively discharge energy from the energy storage device to the motor-generator to assist the powertrain or to charge energy from the motor-generator to the energy storage device for future use. In an aspect, the regulation strategy may maintain a consistent speed of an internal combustion engine associated with the powertrain. In another aspect, the regulation strategy may regulate simultaneous operation of first and second powertrains disposed a parallel relation.
US10183672B2 Method to optimize engine operation using active fuel management
A method for operating an internal combustion engine comprises providing a vehicle having an internal combustion gasoline engine including multiple cylinders and wherein the engine is operating in a deactivated cylinder mode, receiving a torque request if a cylinder reactivation torque smoothing mode is active, setting a variable torque ratio to 1.0 if the torque request is greater than a fast exit threshold torque, setting the variable torque ratio to 0.0 if the torque request is less than a slow exit threshold torque, setting the variable torque ratio to a value between 0.0 and 1.0 if the torque request is between the fast exit threshold torque and slow exit threshold torque, and calculating a component of final engine output torque.
US10183671B2 Torque converter lockup control
A system for managing a lockup clutch in an off-road truck includes an engine, a transmission and a torque converter coupled between the engine and the transmission. The torque converter has a lockup clutch that when engaged directly couples the engine to the transmission. The system also includes a transmission controller that disengages the lockup clutch responsive to sensing a missed shift in the transmission, and subsequent to sensing a completed shift, sets an engine speed limit corresponding to a gear associated with the completed shift, and reengages the lockup clutch.
US10183670B2 Control device for continuously variable transmission of vehicle
The drive system from the engine (1) to the drive wheels (7) of a vehicle is equipped with a torque converter (2), which has a lock-up clutch (3), and a variator (4). Said engined car is provided with a lock-up control means for controlling the engagement/disengagement of the lock-up clutch (3) and a gear change mode switch-controlling means (FIG. 8) for performing control to switch between a “continuously variable gear change mode” and a “DSTEP gear change mode.” While traveling, the gear change mode switch-controlling means (FIG. 8) prohibits gear change by the “DSTEP gear change mode” when the detected oil temperature is at or below a lock-up engagement-permitting threshold for permitting engagement of the lock-up clutch (3) and allows gear change by the “DSTEP gear change mode” when the detected oil temperature is higher than the lock-up engagement-permitting threshold.
US10183668B2 Travel control method and travel control apparatus
A travel control apparatus comprises a first detector configured to detect an obstacle around a subject vehicle traveling in a first lane and a second detector configured to detect a second lane adjacent to the first lane. The travel control apparatus sets a first range at a target position for lane change in the second lane. The travel control apparatus detects a range in the second lane as a second range located at a side of the subject vehicle, and the obstacle is absent in the range in the second lane. The apparatus permits the subject vehicle to change lanes when the second range includes the first range. A method estimates whether another vehicle traveling in the second lane comes away from the subject vehicle and corrects to reduce the first range or increase the second range when the other vehicle is estimated to come away from the subject vehicle.
US10183666B2 Method and device for determining a valid lane marking
The invention relates to a method and a device for determining a valid lane marking (38 to 42; 56, 58) with the aid of a camera system (16) of a vehicle (12), in particular a road vehicle. With the aid of a camera (17) of the camera system (16) several pictures with an image of an area in front of the vehicle (12) are taken successively as a picture series and image data corresponding to the respective picture (30, 54, 66) are generated. The image data of at least a part of the pictures (30, 54, 66) of the picture series are processed, at least a first lane marking (38 to 42) and a second lane marking (56, 58) different from the first lane marking (38 to 42) being detected in at least one picture (30) of the picture series. A vehicle (34) driving ahead of the vehicle (12) is detected in at least two successively taken pictures (30, 54) and its position (P1 to P4) relative to the first lane marking (36 to 42) as well as its position (P1 to P4) relative to the second lane marking (56, 58) is determined. Dependent on the positions (P1 to P4) of the vehicle driving ahead (34) determined with the aid of the pictures (30, 54), one of the detected lane markings (36 to 42, 56, 58) is selected as the valid lane marking (56, 58).
US10183660B2 System and methods for purging an air intake system hydrocarbon trap to a fuel vapor canister
A method for a vehicle engine is presented, wherein during a first condition, a vehicle controller is placed in a sleep mode following a vehicle-off event and then awoken following a duration, at which time contents of an air intake system hydrocarbon trap are purged to a fuel vapor canister by operating an electric motor to rotate the vehicle engine in a reverse direction. Rotating the vehicle engine in a reverse direction causes atmospheric air to enter an intake of the engine via an exhaust of the engine, desorbing hydrocarbons bound to the air intake system hydrocarbon trap. By porting the desorbed hydrocarbons to the fuel vapor canister, bleed emissions from the air intake system hydrocarbon trap may be reduced.
US10183658B2 Combined oil and water separator in an air brake dryer
A filter assembly for separating and removing a liquid from a compressed fluid stream includes a filter element for separating the liquid from the fluid, a purge valve, and an elongated valve operator for actuating the purge valve. The top of the filter element has a shroud that decreases the flow area of the entering fluid stream to induce a vortex of the fluid, allowing the liquid to separate from the fluid. The purge valve is located at the bottom of the filter element for draining the separated liquid. The elongated valve operator axially extends through the filter element and is moveable by an actuating piston located at the top of the filter element, in response to elevated pressure in the filter assembly. The filtered air is dried through a desiccant body and then outputted from the filter assembly to be used in an air brake system.
US10183657B2 Master cylinder
A master cylinder includes a piston seal installed in a circumferential groove. The piston seal includes an annular base section, an inner circumferential lip section protruding from an inner circumferential side of the base section to come in sliding contact with an outer circumferential surface of a piston, an outer circumferential lip section protruding from an outer circumferential side of the base section to abut the circumferential groove, and an intermediate protrusion section protruding from between the inner circumferential lip section and the outer circumferential lip section of the base section to a forward side of the outer circumferential lip section. A step difference section is formed at the outer circumferential side. The circumferential groove has a step section that always abuts an outer circumferential surface of the step difference section. A communication path configured to bring a supply path that is in communication with a reservoir and the bottom section side of the circumferential groove in communication with each other is formed between the step difference section and the step section.
US10183648B2 Wireless authentication device for saddle-type vehicle
A wireless authentication device includes a first operating input device, a locking mechanism, and a controller. The first operating input device receives an operation of a power engine to a startable state by being shifted from a first position to a second position. The locking mechanism switches between locked and unlocked states, the locked state being a state that restricts the shift of the first operating input device from the first position to the second position, and the unlocked state being a state that allows the first operating input device to shift from the first position to the second position. The controller determines whether the mobile terminal is lost through wireless communication with the mobile terminal, and if the power engine has stopped while the mobile terminal has been determined to have been lost, performs processing for keeping the locking mechanism in the unlocked state during a restartable period.
US10183646B2 Occupant restraining apparatus
According to one embodiment, an occupant restraining apparatus includes a webbing W, a tongue 4, an airbag 20 provided along the webbing W, a bag cover 40 surrounding the airbag 20, and a webbing guide 30 through which the webbing W is passed. The webbing guide 30 extends continuously from one end to the other end of the bag cover 40. The lower end of the bag cover 40 surrounds the lower end of the webbing guide 30, and the lower end of the bag cover 40 and the lower end of the webbing guide 30 are bound together. The upper end of the bag cover 40 surrounds the upper end of the webbing guide 30, and the upper end of the bag cover 40 and the upper end of the webbing guide 30 are bound together.
US10183643B2 Transparent vehicle partition
A vehicle partition mounted in a vehicle for separating a driver's compartment and a cargo compartment. The partition has a perimeter defining the outer extent of the surface area. The perimeter is contoured to closely fit within the contoured surfaces of the vehicle. The partition has a top section and a bottom section. The top section is transparent over the entire expanse of the top section extending to the perimeter such that top section can be seen through without visual obstructions over the entire surface area of the top section.
US10183642B2 Secondary impact airbag
Aspects of the disclosure relate to airbag systems for vehicles. The airbag systems may reduce the secondary impact forces felt by an object upon rebounding from an initial impact with an external airbag by encasing or substantially surrounding the pedestrian with the external airbag. The airbag system may include an initial impact airbag and a secondary impact airbag, wherein the secondary impact airbag is configured to reduce injury caused by a secondary impact of an object upon after an initial impact of the object with the initial impact airbag. The initial impact airbag may be configured to be deployed at a location where the object is predicted to collide with the vehicle. The secondary impact airbag may comprise one or more arms configured to surround the object upon the initial impact.
US10183640B2 Systems and methods for door collision avoidance
A vehicle includes: (a) a rotatable door including: a door stop assembly configured to arrest opening of the door; a rotatable handle; a haptic feedback assembly arranged to vibrate the handle; (b) processor(s) configured to simultaneously activate the door stop and haptic feedback assemblies. The haptic feedback assembly is disposed within the rotatable handle. The processor(s) are configured to: compute a time-to-collision, and run the haptic feedback assembly at a level based on the time-to-collision.
US10183639B2 Bumper for a motor vehicle
A bumper for a motor vehicle includes a cross member which is made of light metal alloy and configured as hollow profile to define an interior space and which has a top beam and a bottom beam, with the top beam and/or bottom beam having a recess defined by a marginal area in the form of a collar oriented into an interior space of the cross member. Arranged at an end of the cross member is a crash box formed with a flange sized to overlap at least one region of the cross member in motor vehicle longitudinal direction. A spacer is arranged in the interior space of the cross member and has a chamfer for formfitting engagement by the collar. A fastener is configured for passage of the recess and thereby extending in a motor vehicle vertical direction through the flange of each crash box and the spacer.
US10183636B2 Sealing grommet and cable feedthrough containing a sealing grommet
A sealing grommet for a sealed feedthrough of a strand-shaped element through a wall, in particular for a cable feedthrough for the automotive sector, is configured for insertion in an installation direction into an opening, bordered by the wall and with a predefined opening width. The sealing grommet has a grommet body with a push-through area which extends in the installation direction and which is fed through the opening in the installation direction during installation, in such a way that it engages behind the wall in the installed state. An auxiliary element facilitating the insertion into the opening is provided, which has a circumferential sliding area containing at least one sliding surface, and wherein the at least one sliding surface bears at least partially on a circumferential surface of the push-through area.
US10183635B2 Drainage structure for windshield
A drainage groove includes a basic groove portion that opens toward a front surface side of a windshield between a side end surface on the windshield side and an opposite wall of a front pillar; and an expansion groove recessed from a bottom side of the basic groove portion toward an inside of the windshield in the vehicle width direction. The drainage groove further includes a wall portion configured to protrude toward an opening side of the basic groove portion from a position in a bottom of the basic groove portion which is spaced apart in the vehicle width direction from each of the side end surface on the windshield side and the opposite wall of the front pillar.
US10183630B1 Adapter for mobile device
An adapter securing a mobile device to a vehicle is disclosed. The adapter is positioned between an interior trim part and a vehicle component, and is configured for receiving a cable. The cable includes a connector at a first end of the cable for connecting the cable to the mobile device. The adapter includes a base, a first member extending outwardly from the base, a second member extending outwardly from the base substantially parallel to the first member, and a plurality of cross bars extending between the first member and the second member, the cross bars configured such that the cable may be threaded and looped around the cross bars.
US10183629B1 System and method for retrofitting vehicles with onboard monitoring equipment
Embodiments are directed to a cable harness. The cable harness may include a female connector, a male connector, main wires, and branch wires. The female connector and the male connector may each comply with a Society of Automotive Engineers (SAE) J1962 standard and may each have a plurality of pins. Each of the main wires may electrically couple a respective one of the pins of the male connector to a corresponding respective one of the pins of the female connector. Each of the branch wires may electrically couple to a respective one of the main wires via a respective T-splice. A first pair of the branch wires may provide a branch connection to a first Controller Area Network (CAN) bus wire combination. A second pair of the branch wires may provide a branch connection to a second CAN bus wire combination.
US10183627B1 Bike carrier
A bike carrier contains: a base, a connection rod, a first clutch device, and a second clutch device. The base includes a support rod and a fixing rod rotatably connected with the support rod. The first clutch device is defined between the support rod and the fixing rod of the base, and the first clutch device includes a first rotary knob and a first slider driven by the first rotary knob so that the support rod and the fixing rod are rotatably fixed between a vertical position and a horizontal position. The second clutch device is connected between the base and the connection rod, and the second clutch device includes a second rotary knob and a second slider driven by the second rotary knob so that the base and the connection rod are rotatably fixed among a using position, a collapsible position, and a declining position.
US10183626B2 Console lid integrated dual pawl latching package
A vehicle center console assembly includes a console having a side wall dimensioned to receive a bin therein and a bin including a side wall having a top edge including a pair of opposed strikers. A hinged bin lid includes a dual pawl latching mechanism disposed on a bottom surface thereof whereby the dual pawl latching mechanism does not extend beyond an exterior dimension defined by the bin lid. The bin lid may include a pair of opposed bin lid side walls. The latching mechanism is disposed on the bin lid bottom surface whereby a gap is defined between an outer portion of the latching mechanism and an inner portion of the opposed bin lid side walls. The console side wall includes a top edge configured to define a mating surface for the bin lid side walls.
US10183624B2 Retractable vehicle step
A retractable step for use with a vehicle comprises a stepping member having an upper stepping surface, a first arm, and a second arm. The first arm has a first end pivotally attached to the vehicle, and a second end pivotally attached to the stepping member. The second arm also has a first end pivotally attached to the vehicle, and a second end pivotally attached to the stepping member. The first and second arms can be generally planar linkages.
US10183621B2 Vehicular image processing apparatus and vehicular image processing system
A vehicular image processing system and a vehicular image processing apparatus are provided which combine an image from a photographing device for detection of an object forward of a vehicle and an image from a photographing device for parking assistance, thereby enabling detection, in a synthesized image, of an obstacle of which the entirety cannot be captured by each photographing device since the object is located in a region where detection is difficult in the conventional art, for example, the object is located at a short distance from the own-vehicle.
US10183620B1 Detection and alert system for an ATV with attached plow
A detection and alert system for use with plows and implements is a system generally referring to off-road vehicles such as ATV's and UTV's and comprising a plow system with a detection device in communication with an alert device. A lifting device, such as a winch, is mounted on the front portion of an ATV or UTV for the purpose of raising and lowering the plow blade. When the operator of the ATV raises the plow, a detection device attached to the plow system alerts the operator via alert device, attached to the front portion of the ATV, the gap or distance remaining between the plow system and the ATV or component thereof.
US10183619B1 Vehicle child onboard visual alert device
A noncomplex, extremely inexpensive childcare alert device to prevent a vehicle operator from leaving a child in a vehicle unattended. The system includes an elongated visual display tag that includes a slot for suspending the tag from the shaft of a rearview mirror located in the front seat of the vehicle. The tag body includes indicia that can be bold black letters on a highly bright colorful tag surface that reminds the vehicle operator that the operator should remove an infant in a car seat when exiting the vehicle. The device also includes a vehicle operator wristband that also has printed text reminding the wearer of the infant, to remove a child from the vehicle. The tag can easily be stored in a glove compartment or on a sun visor when not in use.
US10183618B2 System for communication between inside and outside of vehicle
There is provided a system for communication between the interior and exterior of the vehicle, the system including an approach sensor part, a wind ejection part, a light emitting part, a memory part, and a control part. The approach sensor part is installed on a part of a front side or a rear side or both lateral surfaces of the vehicle. The wind ejection part ejects the wind in the direction of the pedestrian or the target object in accordance with a detection result of the approach sensor part. The light emitting part emits a light in the direction of the pedestrian or the target object in accordance with the detection result of the approach sensor part. The memory part stores pattern information on the wind or the light by the wind ejection part or the light emitting part.
US10183616B2 Display system to display outside the vehicle
A display system for motor vehicle comprising a display device configured to produce at least one image; and a window of said vehicle. The display device and the window are arranged such that at least a portion of the at least one image is reflected by at least a portion of the window. This allows make the portion of the image visible from outside the motor vehicle.
US10183615B2 Indicator light to correctly position jack under vehicle in an unlighted environment
A vehicle jack locator system for a vehicle that incorporates a light source such as an LED to direct the operator to the recommended position for the load engaging saddle of a jack is disclosed. The vehicle jack locator system allows the operator to see, even in dark or poorly illuminated environments, the recommended place to position the jack saddle. The system incorporates a vehicle rocker panel having an outer surface and an underside positioned below the outer surface, a rocker panel jack attachment point on the underside of the panel for receiving the jack saddle, a jack placement indicator light positioned on the outer surface of the rocker panel at a point above the jack attachment point and near a tire, and a power system for selectively energizing the light. The power system is a tire pressure sensor system that includes tire pressure sensors and an electronic control module.
US10183613B2 Projection lamp for illumination
A projection lamp for illumination includes a pump radiation unit configured to emit pump radiation, a phosphor element for the at least partial conversion of the pump radiation into a conversion light, and a micromirror array having a multiplicity of micromirror actuators which are arranged in the form of a matrix. The projection lamp is set up such that, during operation, the phosphor element is irradiated by the pump radiation from the pump radiation unit. The conversion light which is thereupon emitted by the phosphor element at least partially makes up an illumination light, which illumination light is guided for adjusting a light distribution over the micromirror actuators. The micromirror actuators are illuminated inhomogeneously with the illumination light at respective times to support the light distribution that is adjusted using the micromirror array.
US10183607B2 Mobile work trailer
A mobile work site having a deployed position and a stowed position for travel is disclosed. Importantly, a first ever vacuum system is configured with permanent piping to the trailer. A vacuum boom is further provided for added versatility. The invention has further been designed with optimal size in mind so that a bulky configuration is made unnecessary. Further the design provides a large amount of horizontal surface area for measuring and planner tables, feeder tables and cutting tables. Additionally, multiple electrical outlets are made available to eliminate any need for long cords. Also, dual, separate and redundant electrical circuits are provided to power the entire trailer. Racks are included herein for transporting lumber and trim materials.
US10183605B2 Utility vehicle
A utility vehicle includes a plurality of ground-engaging members, a frame, a powertrain assembly, a front suspension assembly, and a rear suspension assembly. A cargo bed may be supported by the frame at the rear of the vehicle. The vehicle also includes an operator seat and at least one passenger seat positioned within an operator area. In one embodiment, the vehicle includes doors to enclose the operator area.
US10183603B2 Armrest with deployable cup holder
An armrest is provided for a seat. That armrest includes a body and a deployable cup holder carried on the body. The deployable cup holder includes a translating base and an erectable well wall carried on the translating base. A seat assembly including an armrest is also disclosed.
US10183602B1 Cup holder assemblies having lighting features for console assemblies of vehicles
A cup holder assembly for a console assembly of a vehicle includes a cover, a housing, a light source, and a support frame. The cover includes an exterior surface, an opposite interior surface, and an opening extending between the exterior surface and the interior surface. The housing includes an open ended receptacle defined by a floor and at least one sidewall. The at least one sidewall includes a slit. The housing is connected to the interior surface of the cover such that the opening of the cover permits access to the open ended receptacle. The support frame is connected to at least one of the cover and the housing. The light source is mounted to the support frame such that the light source is positioned adjacent the slit in the at least one sidewall to illuminate an interior of the receptacle.
US10183600B2 Two-piece all-weather floor mat with integreated snap-fit locking feature
A multi-piece floor mat for a vehicle is provided. The floor mat includes a first section and a second section that are configured to assemble to one another to create a single floor mat assembly that spans across two or more floor regions of respective seating areas of the vehicle. The first section has a projection extending therefrom and entirely from a front edge to a rear edge thereof. The second section has a corresponding groove defined therein and extending entirely from a front edge to a rear edge thereof. The groove is configured to receive the projection to interlock the first and second floor mat sections. The projection may be provided with a stem and a bulbous head for additional securement.
US10183599B2 Device and method for adjusting a contour of a vehicle seat with contour adjustment
A device to adjust a contour of a vehicle seat with contour adjustment, may include at least one air cushion connected to a pump via a supply line, a first valve for opening and closing the supply line, and a control and evaluation unit to determine an air volume being supplied to the at least one air cushion via an operating time of the pump and to correlate the air volume being supplied to the at least one air cushion with a contour of the vehicle seat. A related method for adjusting a contour of a vehicle seat with contour adjustment equipped with such a device, may include determining an air volume being supplied to the at least one air cushion via the operating time of the pump, and the air volume being supplied to the at least one air cushion is correlated with a contour of the vehicle seat.
US10183598B2 Device for the variable fixing of a headrest to a seat of a vehicle
A device for the variable fixing of a headrest to a vehicle seat, having a receptacle (1), which forms a receiving space (5) for receiving a headrest support (6), and having a locking rocker (7) which, by means of an actuation movement of an actuation element (11), can be rotated from a locking position, in which a locking section (18) of the locking rocker (7) projects into the receiving space, into a release position, in which the locking section (18) does not project into the receiving space or projects into the receiving space (5) to a lesser extent than in the locking position, is characterized in that the direction of the actuation movement is not oriented perpendicular to the axis of rotation (25) about which the locking rocker (7) is rotatable.
US10183596B2 Vehicle seat
In a detachable vehicle seat, a grip for lifting the vehicle seat is positioned so as to be readily available for installing and removing the vehicle seat without interfering with the vehicle occupant in the installed condition of the vehicle seat. The vehicle seat includes a seat cushion (S1) detachably attached to a vehicle floor, and a seat back (S2) pivotally attached to the seat cushion via a hinge and including a seat back frame (F1), and a grip is provided in a lower part of the seat back frame.
US10183595B2 Device for mechanical vehicle-seat adjustment
A device is provided for mechanical vehicle-seat adjustment, in particular for a motor vehicle or utility vehicle, wherein the device has an actuating handle, which can be moved between an idle position and an actuation position in such a way that a seat part of a vehicle seat is locked in the position of the seat part in the idle position of the actuating handle and can be adjusted in the position of the seat part in the actuation position of the actuating handle. The device is designed in such a way that the actuating handle is guided movably between the idle position and the actuation position exclusively translationally in order to adjust the seat part.
US10183591B2 Electric bicycle and battery lift mechanism and battery carrying device thereof
An electric bicycle and a battery lift mechanism and a battery carrying device thereof are disclosed. The battery lift mechanism includes a bracket, a carrier for carrying a battery, an upward-force device coupling with the carrier, and a locking device selectively in an unlocked state or a locked state. The carrier is movable relative to the bracket along an up-down path; the upward-force device is capable of applying an upward force to the carrier. When the locking device is in the locked state, the locking device interferes with the battery to limit the relative movement between the battery and the bracket. When the locking device is in the unlocked state, the interference between the locking device and the battery is removed, so that the upward-force device drives the carrier carrying the battery to move upward relative to the bracket.
US10183586B1 Mixed-level electric vehicle supply equipment (EVSE) and associated charging methods for multi-type electric vehicles and non-electric vehicle devices
Embodiments include a multi-level electric vehicle supply equipment (EVSE) unit. The multi-level EVSE unit can include a Level 2 charge handle, a receptacle configured to receive the Level 2 charge handle, and a Level 1 outlet including one or more plug outlets configured to receive one or more corresponding Level 1 plugs. The Level 2 charge handle can be permanently attached to the multi-level EVSE unit via a cable. The Level 1 outlet can temporarily receive the one or more corresponding Level 1 plugs. A first power meter associated with the Level 2 charge handle can meter power delivered via the Level 2 charge handle. A second power meter associated with the Level 1 outlet can meter power delivered via the Level 1 outlet. A charging logic and relay section can intelligently allocate power between the Level 2 handle and the Level 1 outlet according to charging rules.
US10183583B2 Energy generation and storage system with electric vehicle charging capability
An inverter includes a battery pack connection for supplying energy to or receiving energy from a photovoltaic string, a battery pack, an AC grid connection for supplying power to or receiving power from an AC grid, a connection for supplying power to a home back-up load, an electric vehicle connection for supplying to and receiving power from an electric vehicle (EV) battery, and a control input configured to receive one or more control signals for controlling the flow of power within the inverter. The inverter, under the control of the one or more control signals, converts power received from one of different power sources and provides the converted power to charge a battery of the EV.
US10183578B2 Vehicle cluster gauge system and method for calibrating the same
A method of calibrating and controlling a gauge, to which a stepper motor is applied in a cluster of hybrid electric vehicle (HEV), includes: receiving information corresponding to an operation state of an electric motor from a certain controller; and controlling a gauge angle indicated by a needle of the gauge to correspond to a target gauge angle indicated by the received information. The step of controlling includes: setting a dropping flag when the target gauge angle is lower than a previous gauge angle; and calibrating the target gauge angle to drop by a reference angle when the target gauge angle corresponds to an angle value that is different from a lowest point of the gauge while setting the dropping flag.
US10183576B2 Methods and systems for alternative fuel container support
A support system is provided for a vehicle. The support system can include one or more bracket assemblies in which each includes a coupling member and a curved member in which the coupling member is affixed to a structure of the vehicle. A housing can be supported by the one or more bracket assemblies in which the housing encloses a container that stores a material such that the housing protects the container and the material. The support system provides movement between a length of the container so as to reduce deterioration of the support system.
US10183568B2 Hybrid drive system
A drive system is provided for a motor vehicle having: a first wheel pair driven by an internal combustion engine and an electric motor; a second wheel pair driven by an electric motor; an internal combustion engine which is coupled to the first wheel pair; a generator which can be operated as an electric motor and which is coupled to the internal combustion engine and the first wheel pair; and an electric motor which is coupled to the second wheel pair and is set up to convert energy produced by the generator into mechanical energy. A planetary gear is provided which is used to couple the internal combustion engine to the generator and the first wheel pair.
US10183566B2 Hybrid vehicle and powertrain
A vehicle includes an engine, motor, transmission, and electronically controlled one-way clutch. The engine includes an output. The motor includes a rotor and a stator. The transmission includes an input that is rotatably coupled to the rotor. The transmission is configured to receive power from the engine and the motor. The electronically controlled one-way clutch has an inner race that is secured to the output of the engine and an outer race that is secured to the rotor. The electronically controlled one-way clutch is configured to rotatably couple the output to the rotor.
US10183565B2 Hydrostatic drive with energy storage
A hydrostatic drive has a hydrostatic pump (3) driven by a drive motor (2) and connected in a closed circuit with a hydrostatic motor (4). The closed circuit is formed by a first hydraulic connection (6a) and a second hydraulic connection (6b). Each of the hydraulic connections (6a, 6b) can form the high-pressure side or the low-pressure side of the closed circuit. A high pressure accumulator device (20) can be connected with the respective high-pressure side hydraulic connection (6a, 6b) and, simultaneously, the respective low-pressure side hydraulic connection (6b, 6a) can be connected with a hydraulic balancing device (30). A valve device (50) is provided for this simultaneous connection. The valve device (50) is a hydraulically controlled shuttle valve device (51) connected to the two hydraulic connections (6a, 6b), the high pressure accumulator device (20) and the hydraulic balancing device (30). The shuttle valve device (30) has a high pressure accumulator path (51a) and a hydraulic balancing path (51b), and is in communication with the two hydraulic connections (6a, 6b) of the closed circuit.
US10183564B2 Body structure of vehicle
A body structure of a vehicle includes a floor panel, a battery pack, an electric water heater (electric apparatus), and a bracket which mounts the electric water heater to the floor panel. The electric water heater is mounted to the floor panel so as to set a battery pack side of the electric apparatus higher.
US10183556B2 Method for regenerating odor absorbent in a motor vehicle HVAC system
A method is provided for regenerating an odor absorbent in a motor vehicle HVAC system. That method includes the step of heating and regenerating the odor absorbent using heat from a heater core of the HVAC system.
US10183555B2 Onboard electric system
An onboard electric system includes a drive circuit that drives an electric motor based on an output voltage of a direct current power supply; a first smoothing capacitor; a drive signal generator; a first discharge resistor that is connected between a positive electrode and a negative electrode of the first smoothing capacitor; a first discharge switcher that is connected in series to the first discharge resistor between the positive electrode and the negative electrode, and releases or makes a connection between the positive electrode and the negative electrode; and an off-signal generator that outputs an off signal to the first discharge switcher. The first discharge switcher is provided by a switcher of a normally-ON type that makes the connection between the positive electrode and the negative electrode through the first discharge resistor in a period other than a period while the off-signal generator provides the off signal.
US10183554B2 Vehicular air conditioning device
An air conditioning refrigerant circuit (6) includes an engine-driven compressor (7) and an electric compressor (11), which are arranged in parallel. When the engine is running, the engine-driven compressor (7) is used. When the engine stops, e.g., when idling stops, the electric compressor (11) is used. At the startup of the engine by a manual operation such as ignition by a key, the engine-driven compressor (7) is kept at rest and instead, the electric compressor (11) is operated for a predetermined time. After the predetermined time, the engine-driven compressor (7) is operated. In this way, the oil recovery to the electric compressor is promoted.
US10183542B1 Suspension control system providing orientation control for an agricultural machine
One or more vehicle sensors can be used in a suspension control system of an agricultural machine to dynamically adjust pistons located proximal to wheels of the machine to substantially control orientation. Such vehicle sensors could include: a speed sensor configured to provide an output indicating a speed of the machine; a turn angle sensor configured to provide an output indicating a turn angle of the machine; and/or an Inertial Measurement Unit (IMU) configured to detect a chassis-to-horizon angle. The output can be compared to a threshold for determining when to control valves in the suspension system to apply height corrections.
US10183541B2 Surround sensing system with telecentric optics
The invention pertains to a system comprising: a source to generate a pulsed radiation pattern; a detector; a processor to process data from the detector when radiation is reflected by an object; a synchronization means interfacing between the detector and the source; wherein: the detector is synchronized with the source so that radiation to be processed is detected only during the pulses, the processor determines a characteristic of the object by determining displacement of detected spots with reference to predetermined positions, the source emits monochromatic light and the detector is equipped with a bandpass filter and optics arranged so as to modify an angle of incidence onto said filter to confine light to a predetermined range around a normal of said filter, said optics comprising an image-space telecentric lens.
US10183539B2 Shock absorber
A shock absorber including: a first cylinder having an interior, first and second ends and defining an axis, wherein the interior includes a damping fluid chamber and a damping piston movably mounted therein for movement between the first and second ends, wherein the damping piston is mounted on a first end of a shaft, wherein the first end of the shaft is movably retained within the interior of the first cylinder; first and second bypass openings configured for opening into the damping fluid chamber at first and second axially spaced-apart positions; a bypass channel fluidly coupling the first and second bypass openings; a fluid metering valve; and a floating piston dividing a portion of the shock absorber into a gas chamber and the reservoir chamber, wherein the fluid metering valve and the floating piston define the reservoir chamber there between.
US10183533B2 Heavy-duty tire
The present disclosure relates to a heavy-duty tire compatible with wear resistance, uneven wear resistance, and wet performance. In the present disclosure, by providing, to a tread section, a pair of center primary grooves, a pair of shoulder primary grooves, a plurality of center lateral grooves, a plurality of middle lateral grooves, and a plurality of shoulder lateral grooves, the tread section is divided into a center block, a middle block, and a shoulder block.
US10183522B2 Security element and method for producing a security element having light-scattering structures
The invention relates to a security element, comprising a thermoplastic or photo-sensitive replication lacquer layer, non-periodic randomly arranged (randomized) structures in the sub-micrometer range being incorporated into the replication lacquer layer and having an angle-independent optical effect, such as a color effect, and to a method for the production thereof and to the use thereof.
US10183519B1 Page bookmarking device
The present utility model refers to a page marker device of the type that can be used between the pages of a book or publication, being that the marker incorporates a writing graphite. The device comprises a strip of graphite partially embedded in the elongate body. The recessed portion of the graphite strip has a length greater than the length of the non-embedded part of the graphite strip, and the elongate thin body has a flat part with a surface suitable for printing.
US10183510B2 Guide device for guiding a printed medium onto a take-up roll in a printing system
The present invention provides a guide device for guiding print medium onto a take-up roll in a printing system. The guide device comprises a first guide member presenting a substantially planar surface for limiting or preventing lateral deviation of a printed medium output from the printing system as the medium moves along a transport path towards a take-up roll for winding or taking up a length of the medium. The first guide member is stationary in use. A position of the first guide member is adjustable in a direction transverse to the transport path for setting the position to limit or prevent lateral deviation of the medium along the transport path. The guide device further comprises a second guide member presenting a support surface configured and arranged to support the medium thereon as the medium travels along the transport path towards the take-up roll. The first guide member and the second guide member are preferably integrally formed as a guide unit. Further, the invention provides a printing system which incorporates such a guide device.
US10183502B2 Pretreatment agent for ink jet textile printing and ink jet textile printing process
Provided is a pretreatment agent for ink jet textile printing that can provide printed matters on fabric with high color-developing properties and less bleeding. The pretreatment agent includes at least water and (A) a multivalent metal ion and polymer fine particles, (B) a cationic polymer and polymer fine particles, or (C) cationic polymer fine particles.
US10183497B2 Color correction in printing systems
A method is described in which a first color is detected at a user-selected arbitrary position of a first print; a second color is detected at a user-selected arbitrary position of a second print printed by a printer; a color difference between the first color and the second color is determined; and settings of the printer are changed to reduce the color difference in further prints printed by the printer.
US10183496B2 Ink jet printing with high drop weight (HDW) planes and low drop weight (LDW) planes
Printing methods and systems are described herein. In one example, a method includes rasterizing a document to create color rasters and linearizing the color rasters to create high drop weight (HDW) planes and low drop weight (LDW) planes. HDW and LDW halftone planes are created from the HDW and LDW planes. The HDW and LDW halftone planes are masked to create HDW and LDW printhead maps, and the HDW and LDW printhead maps are merged into print data. The print data is sent to a number of printheads.
US10183495B2 Liquid supply device, printing apparatus and liquid ejection system
A technique of reducing the possibility that a liquid remains in a buffer chamber is provided. There is provided a liquid supply device configured to supply a liquid to a liquid ejection head. The liquid supply device comprises a liquid containing chamber configured to contain the liquid; an air communication path configured to include a first connection portion at one end that is connected with the liquid containing chamber and an air outlet port at the other end that is open to the atmosphere; and a buffer chamber provided in the middle of the air communication path. The air communication path includes a connection path that is located on a downstream side of the buffer chamber in the air communication path in a flow direction of a fluid from the air outlet port toward the liquid containing chamber and is configured to include a second connection portion at an upstream end connected with the buffer chamber. When the first connection portion is exposed to the liquid in the liquid containing chamber, the second connection portion is placed in a lower area in a vertical direction of the buffer chamber.
US10183494B2 Inkjet recording apparatus
An inkjet recording apparatus includes an ink container. The ink container stores an ink for printing on a printing object. The inkjet recording apparatus also includes a stirring mechanism. The stirring mechanism stirs the ink stored in the ink container. The stirring mechanism includes a stationary shaft and a rotating body. The rotating body rotates around the stationary shaft. The stationary shaft and rotating body are placed in a lower part of the ink container.
US10183487B2 Liquid discharge apparatus
There is provided a liquid discharge apparatus including: first and second liquid discharge heads and a controller. The first liquid discharge head includes n of nozzles NA1-NAn and m of nozzles NB1-NBm. The second liquid discharge head includes m of nozzles NC1-NCm. The first and second liquid discharge heads include m of nozzle pairs (NB1, NC1)-(NBm, NCm) A difference of position between the nozzle NBj and the nozzle NCj in the first direction is smallest in the j-th nozzle pair (NBj, NCj), of them of nozzle pairs (NB1, NC1)-(NBm, NCm), and a difference between the use rate RBp of the nozzle NBp and the use rate RCp of the nozzle NCp is smallest in the p-th nozzle pair (NBp, NCp) different from the j-th nozzle pair (NBj, NCj), of the m of nozzle pairs (NB1, NC1)-(NBm, NCm).
US10183486B2 Inkjet printer, time synchronization method therefor, and setting screen using same
When printing on the same printing object with multiple print nozzles in the past, consideration was not given to cases in which the time relationships of the set times and times-to-be-printed become mismatched between the respective print items of the print nozzles. To solve this problem, an inkjet printer that prints on a conveyed printing object and has multiple print nozzles, multiple auxiliary control units for controlling the printing performed by the multiple print nozzles, and a common main control unit connected to the multiple auxiliary control units via communication unit is provided. The main control unit extracts the time relationship of the set times and the time relationship of the times-to-be-printed between the items to be printed by the respective print nozzles of the multiple print nozzles and revises the print data so as to preserve the time relationship of the set times.
US10183484B2 Method for detecting an operating state of an inkjet print head nozzle
For assessing the functioning of an ejection unit of an inkjet print head, a comparison of a residual pressure wave with a residual pressure wave reference is employed. To enable assessment during printing, multiple residual pressure wave references are provided, each relating to a condition relevant to the residual pressure wave. Such a condition may relate to an actuation status of an adjacent ejection unit which may cause crosstalk, for example. When performing the assessment, the condition during assessment is taken into account, for example for selecting a suitable residual pressure wave reference, such that an appropriate and correct assessment can be performed independent from the conditions during assessment.
US10183483B2 Method and inkjet printer for acquiring gap information
A method is provided that is implemented on a control device connected with an inkjet printer, which includes an inkjet head having an ink discharging surface, a head scanning unit reciprocating the inkjet head relative to a recording sheet along a scanning direction parallel to the ink discharging surface, and a wave shape generating mechanism deforming the recording sheet in a predetermined wave shape that has tops of portions protruding in a first direction toward the ink discharging surface and bottoms of portions recessed in a second direction opposite to the first direction alternately arranged along the scanning direction, the method including acquiring gap information related to a gap between the ink discharging surface and each individual one of the tops and the bottoms on the recording sheet, and determining whether the gap information acquired for each individual one of the tops and the bottoms is abnormal.
US10183481B2 Energy efficient multi-spectrum screen exposure system
A multi-spectrum screen exposure system for curing printing emulsions, including an enclosure with a platen that is transmissive to at least some ultraviolet wavelengths of light, a cover shiftable between an open orientation wherein the platen is accessible to an operator and a closed orientation wherein the platen is covered and inaccessible to the operator, a light emitting diode illumination (LED) light source assembly supported within the enclosure and oriented to direct illumination toward the platen, the light emitting diode illumination light source assembly emitting at least some light in the ultraviolet wavelengths, and a control unit operably coupled to the light emitting diode illumination light source assembly by which the light emitting diode illumination light source assembly can be operated in a controlled fashion.
US10183474B2 Method for providing a lamination film with adhesive, method for applying hot melt, application, lamination plant and method for upgrading such a plant
A method for providing a laminate film with adhesive as a step in the preparatory process for manufacturing a laminate mold part using a support part, a method for applying a hot melt to a laminate film, a method for manufacturing a laminate mold part, using a method, a system for laminating a support part as well as a method for such a system produces especially high quality lamination and even if the support part, where the laminate film should be laminated, is not porous by applying the adhesive to the support part for bonding the macroscopically structured laminate film, so that there is a duct system. The air can flow through the duct system between the laminate film and the support part during the lamination process.
US10183473B2 Sheet processing system
A sheet processing system for producing a printed item. The system includes a sheet feeding station to feed printed sheets one at a time, adjacently, to a laminating station to adhere a laminating material to the printed sheets, and a base item application station to apply a base item to the printed sheets, thereby turning each of the fed single printed sheets into a continuous printed sheet.
US10183470B2 Composite glass
A flame-retardant composite glass including a plurality of glass panes and a flame-retardant intermediate layer that is arranged between two first glass panes and includes a flame-retardant material that foams or swells up in the event of a fire, as well as an attack-resistant layer having a transparent plastic that is solid at room temperature. The flame-retardant composite glass has, between the first glass panes, an edge compound extending along and around the edges such that a chamber filled with said flame-retardant material is defined by the first glass panes and the edge compound. Between at least one of the first glass panes and the flame-retardant material, a primer layer is arranged that includes a material whose adhesion to the flame-retardant intermediate layer and/or to the glass pane becomes weaker in flame-retardant test conditions than it is in room temperature conditions.
US10183468B2 System, method and apparatus for tolerance ring with functional layers
A tolerance ring with functional layers has an annular band and an elastomeric layer. The assembly also may have a low friction layer, which may be bonded, calendared or laminated thereto. The low friction material may completely encapsulate the annular band.
US10183467B2 Encapsulated beam and method of forming
A device including a protecting material encapsulated metallic beam and a method of encapsulating the metallic beam using the protecting material layer are presented. The device includes a cantilever beam that includes at least about 90 Wt % of a metallic beam material, and 10 Wt % or less of a protecting material. The method of forming an encapsulated metallic beam includes the steps of depositing a first layer of protecting material over a substrate, depositing a second layer of protecting material over the first layer, depositing a metallic beam material over the second layer of protecting material, and encapsulating the beam material with a coating of the protecting material.
US10183466B2 Transparent electroconductive film with protective film
A transparent electroconductive film with a protective film includes: a transparent electroconductive film including a film substrate, an optical adjustment layer formed on one main surface of the film substrate, and a transparent conductive layer formed on the optical adjustment layer; and a protective film bonded to a main surface of the film substrate on a side opposite to the transparent conductive layer, wherein the transparent electroconductive film and the protective film are thermally shrinkable in at least one direction in a main surface, and the absolute value of the maximum thermal shrinkage ratio (%) of the transparent electroconductive film in a main surface is smaller than the absolute value of the maximum thermal shrinkage ratio (%) of the protective film in a main surface, and the difference between the absolute values is 0.05% to 0.6%.
US10183462B2 Pre-fabricated ceiling assembly and method of forming
A prefabricated ceiling panel and method of forming the same is provided. The panel comprises various built-in features including cable trays, lighting elements, and other features. The panel further comprises a layered structure comprising a plurality of layers to increase the fire resistance, insulation, and/or structural features of the panel.
US10183458B2 Insulated packaging and method of making same
Insulated packaging is provided including an inner substrate and an outer substrate attached to the inner substrate to form an air gap therebetween. An expandable material including expandable microspheres is provided with the expandable material disposed between the inner substrate and the outer substrate. An adhesive material different than the expandable material is disposed between the inner substrate and the outer substrate to attach the inner substrate to the outer substrate. A method for forming the insulated packaging is also provided.
US10183457B2 System and method for exchanging vertically segmented rotor segments on a rotary tablet press
Disclosed is a system and a method for exchanging vertically segmented rotor segments (16) on a rotary tablet press (34). The system comprises a rotor (10) comprising at least two vertically segmented rotor segments (16), a transfer unit (36) and an assembly carriage (38).
US10183454B2 Cylindrical-member forming method and device
Provided are a method and device for forming a cylindrical member for accurately forming belt-like members into a cylindrical shape without meandering. A pre-winding position sensor detects a position of a member reference line extending in a longitudinal direction of a belt-like member along the entire length of the belt-like member in the longitudinal direction thereof before the belt-like member is placed on a transport conveyor belt, transported to a forming drum, and wound around the forming drum. The belt-like member is wound around the forming drum and formed in a cylindrical shape while the forming drum is relatively moved in the drum width direction with respect to the transport conveyor belt by a controller and the member reference line, based on the detected data and a position data of the drum reference line orthogonal to the drum axial center of the forming drum.
US10183453B2 Process for manufacturing an intraocular lens with an embedded mask
Intraocular implants and methods of making intraocular implants are provided. The intraocular implant can include a mask adapted to increase depth of focus. The method of manufacturing the implant can include positioning the mask with an aperture on a protruding pin of a positioning mold portion. The protruding pin can be configured to center the mask in the intraocular lens.
US10183451B2 Method for repairing a composite-material panel of an aircraft and tool for implementing said method
A method and a tool for repairing a composite-material panel of an aircraft with at least one repair part made of composite material without using an autoclave. The repair method includes the steps of preparing the panel, placing at least one repair part made of composite material on the second face to cover a damaged zone, positioning a vacuum bag configured to sealingly cover the repair part, polymerizing or consolidating the repair part, compressing the vacuum bag against the repair part using a compression plate concomitantly with the step in which the repair part is polymerized or consolidated.
US10183450B2 Method for impregnation of a fibrous preform and device for implementation of the said method
A method of impregnating a fiber preform with an impregnation composition, includes applying a liquid on a structure, the structure including a chamber in which a fiber preform for impregnating is present, the chamber being defined between a rigid support on which the fiber preform is placed and a wall, the wall having a face situated facing the fiber preform; and an impregnation composition for impregnating the fiber preform, the impregnation composition being present in the chamber; the liquid being applied against the wall on its side opposite from the chamber, the wall being configured so that its face situated facing the fiber preform conserves its shape during the application of the liquid, the applied liquid enabling sufficient pressure to be created to move the wall towards the rigid support and impregnate the fiber preform with the impregnation composition.
US10183448B2 Back seam welder and method of operation
A thermal welder is configured to weld a back seam of a bag formed of thermoplastic sheet material. The welder may include a weld heater and a compression mechanism downstream of the weld heater to compress the sheet material to form the back seam. The welder may also include a weld breaker downstream of the compression mechanism to break apart incidental welds which are formed adjacent the back seam.
US10183444B2 Modular multi-station three-dimensional object printing systems
A three-dimensional object printing module has been developed. The printing module includes a first processing station configured to perform an operation. The printing module further includes a track configured to guide a cart moved by a motive force in a first direction to the first processing station and to guide the cart moved by the motive force in the first direction from the first processing station. The printing module further includes at least one lead screw disposed parallel to the first direction along the track at the first processing station and configured to engage the cart at the first processing station. The printing module further includes an actuator operatively connected to the at least one lead screw and configured to rotate the lead screw bi-directionally about a longitudinal axis of the lead screw to enable the cart to move along the track at the processing station without the motive force.
US10183443B2 Electrostatic 3-D printer controlling layer thickness using feedback loop to development device
3-D printers include an intermediate transfer surface that transfers a layer of material to a platen each time the platen contacts the intermediate transfer surface to successively form a freestanding stack of layers of the material on the platen. A sensor detects the thickness of the layer on the platen after a fusing station fuses the layer. A feedback loop is electrically connected to the sensor and a development station (that includes a photoreceptor, a charging station providing a static charge to the photoreceptor, a laser device exposing the photoreceptor, and a development device supplying the material to the photoreceptor). The development station adjusts the development bias of the development device, based on a layer thickness measurement from the sensor through the feedback loop, to control the thickness of subsequent ones of the layers transferred from the intermediate transfer surface to the freestanding stack on the platen.
US10183442B1 Medical devices and methods for producing the same
The present disclosure relates generally to medical devices, including airway stents, and additive manufacturing (3D printing) processes for producing the same. Using certain materials and novel printing techniques, the present systems and methods can directly print nearly any size or shape medical device in a few hours. For example, in certain embodiments, the present systems and methods leverage fused deposition modeling (“FDM”) and polycarbonate urethane (“PCU”) to produce custom medical devices, including airway stents.
US10183440B2 Blow molder control systems and methods
Systems and methods for controlling the operation of a blow molder are disclosed. An indication of a crystallinity of at least one container produced by the blow molder may be received along with a material distribution of the at least one container. A model may be executed, where the model relates a plurality of blow molder input parameters to the indication of crystallinity and the material distribution and where a result of the model comprises changes to at least one of the plurality of blow molder input parameters to move the material distribution towards a baseline material distribution and the crystallinity towards a baseline crystallinity. The changes to the at least one of the plurality of blow molder input parameters may be implemented.
US10183439B2 Method for hydroforming a container from a preform
A method of hydroforming a container from a preform. During the method, an injection nozzle is moved from a retracted position, where the nozzle is spaced away from the neck of the preform, to an intermediate position, where contact is established between a first contact surface of the nozzle and the finish of the preform. The nozzle is then moved from the intermediate position to an injection position, where a second contact surface of the nozzle abuts an abutment surface and the neck is axially compressed. With the nozzle in the injection position, a liquid is injected from the nozzle into the preform causing the preform to expand and form the container.
US10183438B2 Apparatus and method for fabricating containers
An injection head for a container-fabricating apparatus. The injection head includes a first nozzle establishing fluid communication between an injection liquid source and a preform cavity of a substantially tubular preform. The first nozzle is configured to mate with a mouth of the preform. An annular mouth seal, provided in the first nozzle, creates a seal with the mouth of the preform when disposed in contact therewith.
US10183430B2 Method for injection molding of thermoplastic pole parts, and mold for producing the same
A method for injection molding of thermoplastic pole parts utilizes a mold to fix at least one vacuum interrupter and contact terminals during a molding process. At least one injection opening or gate for injection of thermoplastic material is formed into the mold. The mold is applied with multiple injection openings at least along its long axis, for injection of hot thermoplastic material, and the injection openings or gates can be steered in such a way that they inject thermoplastic material simultaneously or with a defined time dependent injection pattern. This process alleviates the issue of a pressure gradient along the long axis of the molded pole part, shortens process times, and achieves a homogenous dissipation of material during the molding process.
US10183429B2 Method and device for the production of an injection-moulded part
A method for the production of an injection-molded part including casting an injection-molding material at least two injection-molding stations by at least two injection-molding processes. A pre-molded part, produced in one of the at least two injection-molding processes, is cooled in a cooling station between the at least two injection-molding processes.
US10183428B2 Unit cell injection mold for fuel cell
A unit cell injection mold for fabricating a unit cell of a fuel cell, in which an integrated frame of the unit cell formed by injecting a polymer resin onto an insert, in which a membrane electrode assembly and a gas diffusion layer are integrated, is formed, the unit cell injection mold includes an upper mold, a lower mold engaged with the upper mold to define an inner space between the lower mold and the upper mold, the inner space including an injection area into which the insert is accommodated and an insert area into which the polymer resin is injected to form the frame, and elastic protrusions formed from an elastic material, the elastic protrusions being disposed on the upper mold and the lower mold to face each other, wherein the elastic protrusions clamp the insert to divide the inner space into the insert area and the injection area to prevent the polymer resin from entering the insert area.
US10183426B2 Water as a propellant for thermoplastics
The present invention relates to a process for the production of an expandable thermoplastic polymer comprising water as blowing agent, comprising at least the step (A) of storage of the thermoplastic polymer in water, so that water is absorbed by the thermoplastic polymer, in order to obtain an expandable thermoplastic polymer, to expandable thermoplastic polymer, obtainable via the process, to a corresponding expanded thermoplastic polymer, to a process for the production of a foam via foaming and fusion of the expanded thermoplastic polymer, and also to a foam, obtainable via said process.
US10183418B2 Dynamic segregation monitoring of concrete
A system and process for detecting dynamic segregation in concrete rotated within a mixer drum, such as mounted on a delivery truck. A system processor is programmed to monitor an instantaneous and averaged rheology parameter and to deploy protocols for detecting segregation. A first protocol comprises monitoring the averaged slump during and immediately after a jump in drum speed of at least plus or minus four rotations per minute and detecting when a change in the averaged slump value meets or exceeds a threshold; and a second protocol comprises monitoring the instantaneous slump when the mixer drum is rotating at a constant speed for at least three successive rotations and detecting when the instantaneous slump value meets or exceeds a threshold limit. Once segregation is detected, one or more operations can be initiated, such as initiating an alarm or adjusting the mix.
US10183417B2 Electrosurgical instrument
An electrosurgical instrument is manufactured by presenting an electrode, and attaching a sacrificial portion to the electrode to form a first electrode assembly. An insulating material is molded over the first electrode assembly to form a second electrode assembly, and the second electrode assembly is subjected to a further process which is capable of removing the sacrificial portion without removing the insulating material. The sacrificial portion is removed to form at least one cavity within the electrosurgical instrument.
US10183416B2 Wood board and process for its production
The present application relates to wood boards, particularly post-cured wood boards and more particularly to particle board with excellent swelling properties; it also relates to a process for production of such boards.
US10183415B2 Table saw
A table saw includes a table, a saw, a track, a slide strip, and a fence member. The table has an axial direction and a radial direction which are orthogonal to each other. The saw is arranged at a predetermined position of the table. The track is arranged at each side of the table. The slide strip is slidably engaged with the track. An outer surface of the slide strip opposite to the track has a first position part, a second position part, and a third position part. The first position part and the second position part are respectively arranged at two ends of the slide strip and the third position part is arranged at a center of the slide strip. The fence member is bridged on the table and secured to one of the first position part, the second position part, and the third position part.
US10183410B2 Vegetable stick maker
A vegetable stick maker includes a plunger and a hollow body, each of which has a height which is much greater than its width. The body is configured with one or more blades extending across the hollow interior of the body so that a vegetable pushed through the body by the plunger will encounter the blades and be sliced accordingly. The plunger includes a terminal end that diverges into a plurality of legs configured to receive the blades to facilitate slicing. A cap on the plunger prevents the plunger from extending beyond a rim of the body.
US10183406B2 Thumb stud including tritium
A thumb stud for a folding knife assembly includes a body extending between a first end and a second end. A hollow passage extends between the ends, and a tritium vial is disposed within the hollow passage and extends between the first and second ends. A first lens is disposed within the hollow passage adjacent the first end and a second lens is disposed within the hollow passage adjacent the second end. The first and second lenses encapsulate the tritium vial within the hollow passage of the body and allow illumination produced by the tritium vial to be viewable through the first and second lenses to illuminate the thumb stud. In an alternative arrangement, the tritium vial can be replaced with a wafer which houses the tritium vial. In this arrangement, a pair of wafers are each disposed adjacent respective lenses at respective ends of the body.
US10183405B2 Robot, gear device, and manufacturing method for gear device
A robot includes a first member, a second member that is provided so as to be movable around the first member, and a gear device that transmits driving force from one of the first member and the second member to the other. The gear device includes an internal gear, a flexible external gear that has an external tooth portion, which partially meshes with the internal gear, and a body portion, which is linked to the external tooth portion in a direction of a rotation axis, and a wave generator that comes into contact with the external gear and moves a position where the internal gear and the external gear are meshed with each other in a circumferential direction. An exterior surface of the body portion has an oil-repellent portion of which oil repellency is higher than oil repellency of an exterior surface of the external tooth portion.
US10183401B2 Mass transfer tool
Systems and methods for transferring a micro device from a carrier substrate are disclosed. In an embodiment, a mass transfer tool includes an articulating transfer head assembly, a carrier substrate holder, and an actuator assembly to adjust a spatial relationship between the articulating transfer head assembly and the carrier substrate holder. The articulating transfer head assembly may include an electrostatic voltage source connection and a substrate supporting an array of electrostatic transfer heads.
US10183400B2 Reusable buoyancy modules for buoyancy control of underwater vehicles
A water environment robotic system and method has a buoyancy configuration which can be selectively altered. The system includes an underwater robotic vehicle and a buoyancy module that is configured to be selectively buoyantly engaged and buoyantly disengaged with the underwater robotic vehicle. A tether is connected to the buoyancy module and a motor is operatively connected to the tether and is configured to extend and retract the tether and buoyancy module. The tether can be extended and retracted to extend and retract the buoyancy module. Extending and retracting the buoyancy module can buoyantly engage or buoyantly disengage the buoyancy module with the underwater robotic vehicle according to the arrangement of the system. By engaging and disengaging the buoyancy module, the buoyancy of the underwater robot can be selectively altered.
US10183399B2 Six-axis motion mechanism
A six-axis motion mechanism combines three translation axes in the directions of the X-axis, the Y-axis, and the Z-axis and three rotation axes in the directions of the x-axis, the y-axis, and the z-axis to carry out a six-axis compound motion. The six-axis motion mechanism includes a movable support frame provided with a connecting mechanism. Drive mechanisms are provided in the directions of the X-axis, the Y-axis, and the Z-axis respectively for controlling the displacement, velocity and acceleration of three translation axes. Rotation mechanisms are provided in the directions of the x-axis, the y-axis, and the z-axis respectively for controlling the rotation angles (θ, φ, Ψ), angular velocity, and angular acceleration of the three rotation axes. The six-axis motion mechanism further includes a motion body which can proceed its rotation and displacement at any angle to imitate a single motion of rolling, yawing and pitching and a compound motion.
US10183396B2 Mass transfer tool manipulator assembly with remote center of compliance
Systems and methods for transferring a micro device or an array of micro devices to or from a substrate are disclosed. In an embodiment, a remote center robot allows on-the-fly alignment between a micro pick up array and a target substrate. The remote center robot may include a plurality of symmetric linkages that move independently and share a remote rotational center. In an embodiment, the remote rotational center may be positioned at a surface of the micro pick up array to prevent damage to the array of micro devices during transfer.
US10183393B2 Level referencing drill guide
A device which includes a guide member which includes a first end portion and an opposing second end portion. The first end portion defines a first plane and an opening is defined by the guide member, wherein the opening extends along the guide member in a direction perpendicular to the first plane. The device further includes a first bubble vial attached to the guide member wherein the first bubble vial extends within a second plane. The device further includes a second bubble vial attached to the guide member, wherein the second bubble vial extends within a third plane, the second and third planes are in angular relationship relative to one another and the first and second bubble vials are each rotationally adjustable relative to the guide member.
US10183386B2 Blind hole puller with interchangeable actuator
A blind hole puller kit includes a plurality of different sized collets, a plurality of pins, an adapter, and a pulling device. The pins have differently sized first ends corresponding to the collets, and second ends that include a common mounting interface receivable in the adapter. A pin corresponding to a desired collet is configured to be mounted via it mounting interface into the adapter to form an actuating device. The actuating device, via an external thread of the adapter, is configured to be threaded into an internal thread of the collet to actuate tines of the collet to grip the inner surface of a hole to be pulled. An end of the adapter opposite the pin is configured to be mounted to the pulling device, whereby the pulling device can be operated to pull the hole.
US10183385B2 Locking structure for hand tool
A locking structure for a hand tool contains: a body having a driving head which includes an accommodation chamber and a rib, and between two ends of the rib is defined an opening. The rib has two positioning orifices, the accommodation chamber has an obliquely arcuate groove accommodating a ratchet member which has a toothed rim and two opposite apertures, and a part of each steel ball extends out of each aperture. The ratchet member further has a first trench, a polygonal groove, and a second trench. A cap is covered on the rib and includes a through orifice, an open section, a protruded section, an actuation extension, and two opposite openings so as to house two posts respectively, wherein a part of each post extends out of each opening, and a resilient element is defined between the second trench and the cap.
US10183380B2 Modular fixture plate system for positioning a workpiece during a manufacturing and/or inspection process
A modular fixture plate system comprising: at least one interlocking fixture plate comprising at least one of a male end and a female end, wherein the male end comprises at least one male projection and the female end comprises at least one female recess; and a docking plate comprising at least one of at least one male projection and at least one female recess; wherein at least one male projection or female recess of the at least one interlocking fixture plate is interlocked with a mating one of the at least one male projection or the at least one female recess of the docking plate.
US10183377B2 Method of standardizing grinder burn etch testing
A method of standardizing a grinder burn etch test may include machining a test sample of substantially equivalent chemical composition and heat treatment to a manufactured part to be audited for grinder burn and receiving data on an expected range of thermal damage that may be caused on the manufactured part during grinding by grinder burn. The method may also include preparing the test sample by laser heat treating at least a portion of the test sample to create a range of thermal damage across predetermined areas on the test sample, wherein the range of thermal damage on the test sample encompasses the expected range of thermal damage that may be caused on the manufactured part during grinding by grinder burn. The method may still further include testing a grinder burn etch bath with the test sample to determine whether the etch bath can detect thermal damage across at least a threshold percentage of the expected range of thermal damage that may be caused on the manufactured part.
US10183376B1 Carrier for mounting a bar of sliders or a stack of such bars to be lapped
Embodiments of the present disclosure include carriers for a row bar or stack of row bars to be lapped. In some embodiments, the ratio of the coefficient of thermal expansion of at least the bridge of a carrier to the coefficient of thermal expansion of the slider row bar or stack of slider row bars is less than 1.6. In some embodiments, a carrier can include a bridge having a length longer than the row bar or stack of row bars. In some embodiments, one or more bridge bending members can have junction centerlines offset from the corresponding bridge bending members.
US10183375B2 Batch-processing method for super-high aspect ratio diffractive optics
A method for fabrication of diffractive optics by batch processing is disclosed, having applicability to high resolution ultra-high aspect ratio Fresnel Zone Plates for focusing of X-rays or gamma-rays having energies up to hundreds of keV. An array of precursor forms is etched into a planar substrate. Sidewalls of the forms are smoothed to a required surface roughness. A sequence of alternating layers of different complex refractive index, for binary or higher order diffractive optics, are deposited on the precursor forms by atomic layer deposition (ALD), to provide diffractive line patterns. Thinnest layers may have nanometer thicknesses. After front surface planarization and thinning of the substrate to expose first and second surfaces of the diffractive line patterns of the diffractive optic, the height h in the propagation direction provides a designed absorption difference and/or phase shift difference between adjacent diffractive lines. Optionally, post-processing enhances mechanical, thermal, electrical and optical properties.
US10183370B2 Constant temperature water supply system
A constant temperature water supply system that adjusts water from a water supply source to a constant temperature by a constant temperature water supply apparatus and supplies the water to a processing apparatus. The constant temperature water supply apparatus is provided with water temperature adjusting units that adjust processing water and cooling water to predetermined temperatures and temperature adjustment control units that reset predetermined temperatures of the water temperature adjusting units. The processing apparatus is provided with water temperature detectors that detect the water temperatures of the processing water and the cooling water and water temperature managing units that each calculate the temperature difference between the water temperature detected by the water temperature detector and a desired temperature set in advance.
US10183369B2 Cutting fluid supply system to machine tool
A cutting fluid supply system includes a machine tool, a nozzle for ejecting cutting fluid, and a nozzle-moving unit for holding and moving the nozzle. The cutting fluid supply system detects an object existing in the machine tool, recognizes a position and a shape of the object based on the detection information, and specifies a machining point from the recognized information. The nozzle-moving unit moves the nozzle such that cutting fluid is ejected to the specified machining point.
US10183367B2 Tool-support system
A tool-support system for working on holes of a surface. The tool-support system includes two rails fixed to the surface and having imprints regularly distributed over their length, and a mobile tool-support including a mobile optical system capturing an image of the surface. For each rail, at least one wheel is adapted to be moved on the rail, and includes on its rolling strip counter-imprints complementary to the imprints. A mobile tool carries a working tip, and a control unit is configured to control the movement of the mobile tool-support, of the tool and of the optical system to analyze an image captured by the optical system and to detect the presence of a hole. A tool-support system of this kind can therefore move along the rails without slipping while detecting the holes to work on them.
US10183362B2 Clad aluminum alloy material with excellent corrosion resistance and brazeability and method for producing the same
A clad aluminum alloy material exhibiting favorable corrosion resistance and brazeability in an alkaline environment is shown by a clad aluminum alloy material with excellent brazeability and corrosion resistance in which one surface of an aluminum alloy core material is clad with a sacrificial anode material and the other surface is clad with brazing filler material. The core material includes an aluminum alloy of Si: 0.3-1.5%, Fe: 0.1-1.5%, Cu: 0.2-1.0%, Mn: 1.0-2.0%, and Si content+Fe content ≥0.8%, wherein the 1-20 μm equivalent circle diameter Al—Mn—Si—Fe-based intermetallic compound density is 3.0×105 to 1.0×106 pieces/cm2, and the 0.1 μm to less than 1 μm equivalent circle diameter Al—Mn—Si—Fe-based intermetallic compound density is at least 1.0×107 pieces/cm2. The sacrificial anode material includes an aluminum alloy containing Si: 0.1-0.6%, Zn: 1.0-5.0%, and Ni: 0.1-2.0%.
US10183356B2 Welding tool comprising a shoulder, welding method and workpiece
A welding method for connecting at least two workpieces at a connection region by means of friction stir welding using a welding tool having a probe and a shoulder. The method includes rotating the probe around a rotation axis, wherein the connection region is softened by friction heat provided by the probe during said friction stir welding to form a welded seam at the connection region. The method also includes molding, simultaneously with forming the welded seam, at least one of a bevel, a rounding and a chamfer on an edge of the connection region using the shoulder, wherein the shoulder is configured to separate the connection region from the surroundings.
US10183354B2 Weld stud for drawn-arc stud welding
A weld stud for drawn-arc stud welding has a functional portion and a welding portion which represents one end of the weld stud and which is delimited by a front face that is curved outwards in a longitudinal direction of the weld stud.
US10183352B2 Welding wire feed speed control system and method
A welding system is disclosed in which the rate of advancement of wire electrode is determined automatically. The device can include a control circuit that determines the rate of advancement of the wire electrode in response to a signal from the voltage selection device of the welding system. Depending upon the operator selected voltage which is selected via the voltage selection device, the control circuit will determine the appropriate rate of wire electrode advancement and control the advancement mechanism (e.g., electric motor) accordingly. Linking of the voltage level and wire-feed speed controls facilities easy of use for more novice operators and, furthermore, facilitates single-handed adjustment of two operational parameters during a welding process.
US10183349B2 Adjustable shoe for a power tool
A band saw includes a first wheel and a second wheel for supporting a continuous band saw blade, a motor operable to drive at least one of the first and second wheels, a housing supporting the first wheel and the second wheel, a shoe for engaging a workpiece, the shoe including a first detent feature. The band saw also includes a second detent feature cooperating with the first detent feature to hold the shoe with respect to the housing. The shoe is moveable with respect to the housing between an engaged position and a non-engaged position. The shoe is moveable out of the engaged position by application of a force acting to move the shoe with respect to the housing sufficient to overcome cooperation between the first and second detent features in the engaged position.
US10183342B2 Cutting tip
The invention concerns a cutting tip (6) comprising: a core (10) that extends axially; and at least a first branch (12) and a second branch (14) that extend radially from the core (10), each comprising: a proximal portion (12a, 14a) connected to the core (10), a distal portion (12b, 14b), and a central portion (12c, 14c) connecting the proximal portion (12a, 14a) and the distal portion (12b, 14b); and a cutting edge (12d, 14d) extending at least along the distal portion (12b, 14b) and the central portion (12c, 14c); in which: the distal portion (12b) of the first branch (12) is arranged radially forward relative to the central portion (12c) of the first branch (12); and the central portion (14c) of the second branch (14) is arranged radially forward relative to the distal portion (14b) of the second branch (14).
US10183340B2 Twist lock tool system
A tool system including a liner having a body and a plurality of coupling members extending from the body, the body includes a first aperture through which at least part of a tool extends and is configured for coupling to a tool fixture, and a housing having an second aperture through which the at least part of the tool extends, a first end of the housing having grooves configured to mate with the plurality of coupling members to couple the tool within the grooves and to the tool fixture.
US10183339B2 Depth limiting drill
A depth limiting device for a drill includes a main body, an axial braking structure, and a limited shrinking structure. The axial braking structure is attached to the main body. The limited shrinking structure surrounds a drill rod of the drill, is slidably attached to the main body, and is in a home position or a compressed position. The axial braking structure axially brakes the drill rod such that the drill rod moves together with the depth limiting device. When the drill rod enters into a subject, the limited shrinking structure is pressed against the subject, moves from the home position to the compressed position, and stops the drill rod from entering further into the subject.
US10183334B2 Selection system having improved axial locking
A selection system, comprising: a sheath defining an internal housing extending in a longitudinal direction; a link rod disposed in said internal housing, and extending in the longitudinal direction; and a selection slide mounted to slide in the internal housing, about the link rod; the link rod being held stationary relative to the sheath against movement in translation in the longitudinal direction by stop means; the system being characterized in that the stop means comprise: a base that is a body of revolution and includes a conical portion; and a shell comprising two shell portions each including a conical portion configured to come to bear in plane manner against the conical portion of the base.
US10183333B2 Circular cutting insert having non-circular peripheral edge
A cutting tool has an insert holder with an indexable cutting insert removably secured therein. The cutting insert has upper and lower end surfaces with a peripheral side surface and a through bore extending therebetween, and a plurality of upper cutting edges formed on an upper peripheral edge. The peripheral side surface includes a non-circular upper relief surface adjacent the upper peripheral edge and a circular upper abutment surface spaced apart from the upper peripheral edge. Each upper cutting edge exhibits mirror symmetry about a bisector plane, and is non-linear in a side view. The through bore has an inner undercut formed by upper and lower bore surfaces located on opposite sides of a median plane, and a clamping member makes contact with one of the upper and lower bore surfaces at an inner contact zone located between the median plane and a seat surface of the insert holder.
US10183330B2 Skillful three-dimensional printing
The present disclosure various apparatuses, and systems for 3D printing. The present disclosure provides three-dimensional (3D) printing methods, apparatuses, software and systems for a step and repeat energy irradiation process; controlling material characteristics and/or deformation of the 3D object; reducing deformation in a printed 3D object; and planarizing a material bed.
US10183329B2 Quality control of additive manufactured parts
Methods and apparatuses to fabricate additive manufactured parts with in-process monitoring are described. As parts are formed layer-by-layer, a 3D measurement of each layer or layer group may be acquired. The acquisition of dimensional data may be performed at least partially in parallel with the formation of layers. The dimensional data may be accumulated until the part is fully formed, resulting in a part that was completely inspected as it was built. The as-built measurement data may be compared to the input geometrical description of the desired part shape. Where the part fails to meet tolerance, it may be amended during the build process or rejected.
US10183322B2 Method of reusing core sand
A method of reusing core sand includes: crushing a core used for casting into granules; heating the granules at a temperature of 300° C. to 550° C.; causing the heated granules to collide against each other such that water glass used as a binder detaches from the core sand; and blowing air into a mixture of the water glass and the core sand, which are detached from each other, such that the core sand is separated and collected from the mixture due to a difference in specific gravity between the water glass and the core sand.
US10183321B2 Tubular back beam assembly for vehicle and method of manufacturing the same
A tubular back beam assembly may include a plurality of main members, each of which is formed by cold rolling and hot stamping and the plurality of main members may be coupled to form a vertically stacked structure with flat portions coupled in a surface contact fashion, or the tubular back beam assembly may include a main member and at least one support member that are directly coupled to form a vertically stacked structure.
US10183320B2 Method for producing a multi-layer large pipe
A method for producing a multilayer large pipe having an outer support layer and at least one inner liner layer. Advantages with regard to productivity and the properties of the multilayer large pipe are achieved by the sequence of method steps wherein production of a support sheet is pre-bent to a predetermined initial bending radius for the support layer and at least one liner sheet is pre-bent to a predetermined initial bending radius for the liner layer, placement of the at least one pre-bent liner sheet against the inside of the pre-bent support sheet, with a positioning and parallel alignment of its longitudinal edges extending in the direction of the bending axis in order to form the support layer and the at least one liner layer, there is integral joining of at least one of two longitudinal edges of the at least one liner sheet to the support sheet, shaping of the composite of the integrally joined support layer and at least one liner layer to form a slit multilayer large pipe by a bending machine, with nonpositive, frictional engagement in liner regions that are not integrally joined, and there is closing of the remaining gap of the slit multilayer large pipe with a longitudinal seam by welding.
US10183318B2 Method and device for producing a structured surface on a steel embossing roller
A method for structuring a steel embossing roller surface includes using a short pulse laser including at least one of a femtosecond laser and a picosecond laser. The structuring is macrostructuring with dimensions of over 20 μm and depths up to 150 μm and more. The short pulse laser has: in single pulse operation, a fluence in the range of 0.5 J/cm2 to 3.5 J/cm2, and in burst operation, a mean burst fluence of 0.5 J/cm2 to 70 J/cm2 per pulse; a wavelength of 532 nm to 1064 nm; a repetition rate of 1 kHz to 10 MHz; a pulse to pulse spacing on the roller of 10% to 50% of the beam diameter for the femtosecond laser and of 10-25% and 40-50% of the beam width for the picosecond laser; a laser pulse position near the roller surface; and deflection velocities of up to 100 m/s and more.
US10183317B2 Chemical oxidation method and compounds
A method and system for the reduction of contamination in soil and groundwater is provided. Cyclic oligosaccharides can be used, for example, to carry oxidants, carry activators, solubilize organic contaminants and promote biodegradation.
US10183316B2 Sustained release reactant blends
There is provided according to the present invention a sustained release reactant blend and methods for making the sustained release reactant blends. There is further provided methods for using such blends in the in situ or ex situ remediation of contaminated groundwater and in the treatment of water and wastewater. There is further provided, according to the present invention, methods for controllably coating reactant blends whereby such coated blends exhibit sustained release properties and have an open structure.
US10183315B2 Substrate cleaning device
A substrate cleaning device includes: a housing having a cleaning chamber therein; a plurality of spray pipelines pivotally mounted at the housing and distributed side by side along a moving direction of a substrate, each of the spray pipelines is provided with several spray ports configured to direct liquid in the spray pipeline towards a surface to be cleaned of the substrate, and one end of each of the spray pipelines is provided with a transmission gear coaxially fixed thereto; a driving system (4) coupled with the transmission gear and thus configured to drive the spray pipeline, through the transmission gear, to rotate reciprocally at the same frequency, wherein a portion of spray pipelines have a reciprocal rotation direction opposite to that of the other portion of spray pipelines. This substrate cleaning device enables a better cleaning effect for the substrate surface with minimum influence on the traveling speed of the substrate.
US10183308B2 Spraying device
A compact spraying device (10) connectable to a surface and for spraying a fluid comprises a housing (16) with an inlet (20), a pump (28) in fluid communication with the inlet (20), a retractable nozzle (24) in fluid communication with the pump (28), a nozzle cover (22) and a drive system (30). The retractable nozzle (24) selectively extends forward relative to a front side of the housing (16) into a spraying position for spraying the fluid and retracts inside the housing to a retracted position when not spraying. The nozzle cover (22) is selectively moveable from a closed position in which the cover (22) covers the nozzle (24) when the nozzle (24) is in a retracted position, to an open position in which the cover (22) moves to allow the nozzle (24) to extend into the spraying position. The drive system (30) moves the retractable nozzle (24) and the nozzle cover (22) and operates the pump (28).
US10183307B2 Method for applying a flowable substance
A method and apparatus for applying a flowable substance to a flat or curved product using a nozzle unit. The nozzle unit includes a nozzle valve that has a nozzle end with an outlet opening. Moist air and/or temperature-moderated air is admitted to a zone of the nozzle end to form condensation when the supplied moist and/or temperature-moderated air hits the nozzle end zone. Drying up or agglutinating of the flowable substance is thereby prevented at the outlet opening of the nozzle end to secure a continuous, unobstructed flow of the flowable substance from the outlet opening.
US10183306B2 System and apararatus for cost effective automated preparation and coating for large surfaces
An apparatus and method of preparing and coating a large structure such as a ship's hull while in a dry dock wherein a plurality of spray guns disposed in an array are positioned by a robotic arm in a spaced relationship along the surface to be treated so that their spray patterns overlap. The array of spray guns is traversed downwardly and thus painting a strip whereupon the spray guns are secured, move horizontally and then are activated to be moved upwardly until another strip adjacent to and overlapping the first strip is painted. These steps are repeated until the surface area is substantially entirely painted. A shroud is provided for collecting paint oversprays and other excess paint is mounted in the array assemblage. An auxiliary spray gun may be positioned and its spray pattern adjusted to apply paint to area which were missed by the original spray pattern emanating from the array of spray guns. Travel of the system along the work surface is accomplished by a reference track, which may be virtual or actual along which an unmanned platform travels. An articulated computer controlled arm is carried by the unmanned platform which in turn carries the assemblage. Other tools may be selectively operatively connected to the arm for cleaning the hull before a coating is applied thereto.
US10183302B2 Micro fogging device and method
The present invention relates to micro fogging device and method which can spray micro fog-like fine water droplet to be used, for example, for protected cultivation, such as green houses, or barns. The micro fogging device can supply fog tinier than the conventional low pressure foggers, and includes: a low pressure fogger unit for forming fog at low pressure; and a venture nozzle which is coupled to a coupling pipe of the low pressure fogger unit to finely segment/divide the water droplets supplied from the low pressure fogger unit, thereby minimizing usage of water and compressed air and maximizing the effectiveness of fog generation.
US10183295B2 Convective polymerase chain reaction apparatus and optical detecting method thereof
A convective polymerase chain reaction apparatus includes a tube, a temperature control unit, at least one light source and a sensor. The tube includes a cavity used to contain a reaction solution. The reaction solution has a liquid level measured from a bottom of the cavity to a top surface of the reaction solution. The temperature control unit is disposed adjacent to the tube for controlling the temperature of the reaction solution. The at least one light source provides a light beam passing through an incident portion of the tube to excite the reaction solution emitting a fluorescent light. The incident portion is located at a height greater than ½ of a liquid level. The sensor is adjacent to the tube for detecting the excited fluorescence. The light beam has an incident direction forming a non-straight angle with a long axis of the tube.
US10183294B2 Fluid handling device
A fluid handling device includes: a substrate including a first surface and a second surface which are opposite to each other, wherein a first recess which allows fluid to flow therethrough is formed on the first surface; a film including a third surface and a fourth surface which are opposite to each other, wherein at least a pair of second recesses is formed on the third surface; and at least a pair of electrodes whose shape is defined by the second recesses, the electrodes being disposed in the second recesses and configured to apply an electric field to an inside of the first recess, the film being joined to the substrate such that the first surface and the fourth surface face each other.
US10183293B2 Reagent reservoir for fluids
A reagent reservoir for fluids, including a storage chamber connected to a duct for conducting fluid out of, into and/or through the storage chamber. The duct includes a duct section delimited by a substrate and a film joined to the substrate. The duct is sealed and is openable at a predetermined breaking point by deflecting the film. The film also delimits the storage chamber and covers a recess in the substrate which forms the duct section. A sealing wall that seals the duct and is integrally joined to the substrate is placed in the recess. The predetermined breaking point is formed by a breakable joining region between the film and an edge portion of the sealing wall facing the film. The dimensions of a peripheral area of the sealing wall, which is formed in the edge portion and runs parallel to the film, determine the surface area of the joining region.
US10183291B2 Generation and trapping of aqueous droplets in a microfluidic chip with an air continuous phase
The invention relates to a method and system for generating droplets of an aqueous solution on a microfluidic chip with an air continuous phase. Specifically, the droplet generator according to the present invention is integrated into a microfluidic chip to generate and introduce droplets of an aqueous solution into the microfluidic chip. The droplets travelling in a network of chip channels may be captured in on-chip traps in a manner defined by hydrodynamic resistances of chip channels. A biological reaction may be performed on a droplet trapped on the microfluidic chip.
US10183286B2 Noble metal zeolite catalyst for second-stage hydrocracking to make middle distillate
A second-stage hydrocracking catalyst is provided, comprising: a) a zeolite beta having an OD acidity of 20 to 400 μmol/g and an average domain size from 800 to 1500 nm2; b) a zeolite USY having an ASDI between 0.05 and 0.12; c) a catalyst support; and d) 0.1 to 10 wt % noble metal; wherein the second-stage hydrocracking catalyst provides a hydrogen consumption less than 350 SCFB across a range of synthetic conversions up to 37 wt % when used to hydrocrack hydrocarbonaceous feeds having an initial boiling point greater than 380° F. (193° C.). A second-stage hydrocracking process using the second-stage hydrocracking process is provided. A method to make the second-stage hydrocracking catalyst is also provided.
US10183285B2 Process for preparing a molecular sieve
Synthesis of molecular sieves of the STT and ITE framework types using, as a structure directing agent Q, [L(DETA)2]2+ cation or [L(TEPA)]2+ cation, or a mixture thereof, where L is a divalent metal cation comprising at least one of Ni, Co and Mn and DETA is diethylene triamine and TEPA is tetraethylene pentamine.
US10183280B1 Photocatalyst for removing hydroxypropyl guar gum in flow-back fluid of fracturing fluid and preparation method and use thereof
The present invention relates to the photocatalyst field, and discloses a photocatalyst for removing hydroxypropyl guar gum in flow-back fluid of fracturing liquid, and a preparation method and the use of the photocatalyst, wherein, the photocatalyst is expressed by Bi5O7Br0.5I0.5, in a powder form in 12-15 nm particle size, with 285-300 m2/g specific surface area. The photocatalyst has improved response to visible light, has greater specific surface area, and has very high activity in removal of hydroxypropyl guar gum in flow-back fluid of fracturing liquid. In addition, the photocatalyst can be prepared with a simple preparation method under mild conditions, and can be used to remove hydroxypropyl guar gum in flow-back fluid of fracturing liquid.
US10183278B2 Method for preparing the nano-porous oxide-noble metal composite material by deoxidation
The present invention discloses a method for preparing the nano-porous oxide-noble metal composite material by deoxidation, comprising dissolving the noble metal ion or fine particles, the oxide salt to be dissolved and the target oxide salt in the pure water in a proportion to form the mixed solution, adding the surface active agent, and stirring magnetically; dropping the precipitant gradually to form the precipitate, stirring for 4 h, separating and cleaning the precipitate, and drying, grinding and calcining at a high temperature; corroding fully and dissolving part of the oxide with an etchant, preserving the noble metal and the target oxide, separating, cleaning, drying at 80° C., and heat treating at a high temperature to obtain the nano-porous oxide-noble metal composite material. The present invention has the technological advantages of simple operation, low energy consumption, environmental protection and suitable for batching, etc.
US10183277B2 Photocatalytic composition for water purification
Disclosed herein are lightweight and settable photocatalytic compositions and solid composites; methods of preparing the compositions and solid composites; and their use in water purification. The compositions are comprised of photocatalysts such as titanium dioxide (TiO2) and zinc oxide (ZnO), lightweight glass bubbles, and a hydraulic cementing binder. The lightweight and settable photocatalytic compositions can be formed into lightweight photocatalytic solid composites and/or structures by mixing with water and moist curing. Disclosed herein are relatively simple, fast, and cost effective methodologies to photodope the TiO2—ZnO compositions and composites with silver (Ag), to enhance and extend the photocatalytic activity from the ultraviolet into the visible light spectrum. The lightweight and settable TiO2—ZnO and Ag—TiO2—ZnO compositions are used in making solids, structures, coatings, and continuous or semi-continuous water purification panels for purifying contaminated water.
US10183272B2 Adsorbent for heteroatom species removal and uses thereof
Adsorbent materials including a porous material support and about 0.5 wt. % to about 30 wt. % of a Group 8 metal ion are provide herein. Methods of making the adsorbent material and processes of using the adsorbent material, e.g., for heteroatom species separation, are also provided herein.
US10183268B1 Method of manufacturing bio-diesel and reactor
A reactor and process for the production of bio-diesel. The reactor includes one or more coiled reaction lines. The lines are positioned within a tank containing a heat transfer media such as molten salt, maintained at about 750° F. A pump circulates the media within the tank. An emulsion of alcohol; refined feed stock, including glycerides and/or fatty acids; and preferably water is pumped through the reaction lines at temperatures and pressures sufficient to maintain the alcohol in a super-critical state. The curvature of the coils, pump pulsing, and the flow rate of the emulsion keep the emulsion in a turbulent state while in the reactor, ensuring thorough mixing of the alcohol and feed stock. The alcohol reacts with the glycerides and fatty acids to form bio-diesel. The reaction is fast, efficient with regard to energy input and waste generation, and requires minimal alcohol.
US10183267B2 Gas-to-liquids conversion process using electron beam irradiation
A process for converting light alkanes from a natural gas production stream to higher molecular weight hydrocarbons is provided. The method includes transporting the natural gas stream to an electron beam reactor, such as a steel flow-type radiation reactor connected hermetically to an accelerator beam window. The gas stream is exposed to electron beam radiation to generate an upgraded and substantially liquefied hydrocarbon stream. The method then includes transporting the substantially liquefied hydrocarbon stream into a scrubber to remove non-condensed gases. The remaining liquid hydrocarbon stream is then transported as condensate to a distillation tower, where high octane products are separated through fractionation.
US10183264B2 Process for the insertion and conveying of labile additives in streams of molten material
The present invention relates to a process for the insertion and conveying of a labile additive, or a mixture thereof, in a transporting pipe, in which a main stream of molten material flows, said process characterized in that it incorporates said additive, or said mixture, in a portion of the pipe delimited by the main stream, according to one of the following alternative modes: a) in a longitudinal direction with respect to the flow direction of the main stream of molten material, or b) in a transversal direction with respect to the flow direction of the main stream of. molten material, or c) according to a composition of the longitudinal (a) and transversal (b) mode, thus forming a resulting stream which keeps the labile additives segregated from the main stream of molten material.
US10183261B2 Device for preparing an emulsified hot beverage
A milk-whipping device is disclosed. The device includes a heating base, a cylindrical container for the milk which rests on the base and which has a thermal exchange, a sealing closing flange, an impeller inserted in the container to produce an emulsifying effect on the milk; and a pair of connecting arms which can be snap-actuated. The connecting arms are revolvingly constrained to the base and extend along the lateral skirt of the container until hooking onto the closing flange.
US10183260B2 Carbonation unit and process for carbonating a beverage
A carbonation unit which includes a carbonation chamber and an expansion chamber is employed for use in beverage dispensers. The carbonation unit also provides a process for carbonation of a beverage that includes reducing the pressure in the carbonation chamber to a dispensing pressure through the use of the gas expansion chamber.
US10183252B2 Base metal catalyst for treatment of ozone and volatile organic compounds present in air supply
Disclosed herein are base metal catalyst devices for removing ozone, volatile organic compounds, and other pollutants from an air flow stream. A catalyst device includes a housing, a solid substrate disposed within the housing, and a catalyst layer disposed on the substrate. The catalyst layer includes a first base metal catalyst at a first mass percent, a second base metal catalyst at a second mass percent, and a support material impregnated with at least one of the first base metal catalyst or the second base metal catalyst. The preferred catalyst composition is a combination of manganese oxide and copper oxide.
US10183251B2 Microcapsule fabric for absorption and release
A permeable microcapsule embedded fabric acts as a sorbent that creates mold-able, variable geometry fabrics for static or dynamic use. The fabric is composed of micro encapsulated solvent spheres held together by structural members. The fabric provides an excellent means to absorb and separate gases and/or liquids, particularly to separate carbon dioxide from flue gases.
US10183245B2 Water filtration system and water filtration system housing with closing assembly
A water filtration system utilizes a housing configured to utilize various types of filter media and having a press-sealed closing system. The closing system includes a head portion defining a head opening, a lock member, and a lid member. The lock member releasably engages the head portion such that an abutment section of the lock member projects into the head opening. The lid member is received by the head portion to cover the head opening, and has an outward-facing press section configured to abut an inward facing portion of the abutment section of the lock member when the lid member is covering the head opening. Pressure generated within the housing during water filtration presses the lid member in an outward direction and causes the lid member press section to press against the abutment section of the lock member to substantially prevent disengagement of the lock member from the head portion.
US10183244B2 Filter element with central element for a filter system
A filter element (10) has a filter bellows (12) arranged about the longitudinal axis (L) and having a first end disk (14) on a first end face (26), and a second end disk (16) on a second end face (28). A central element (20) is arranged rotatably about the longitudinal axis (L) relative to the filter bellows (12) in the interior (18) of the filter bellows (12). The central element (20) has one or multiple positioning elements (22, 24) which interact with counter positioning elements (116, 118) of an upper housing part (114) to fix the central element in the upper housing part (114) in a defined angular position. The central element (20) has at least one electrical connector element (32) on the element, electrically contacting at least one electrical connector element (120) on the housing.
US10183242B2 Porous inorganic membranes and method of manufacture
A method for making a porous inorganic membrane comprises using a mixture of an inorganic material, organic polymer particles and a solvent to form a slurry. The particles are non-spherical. The method further comprises distributing the slurry onto a surface, drying the slurry to remove the solvent and firing the dried slurry to produce the porous inorganic membrane. Examples of organic polymer particles include particles of acrylic. A substrate comprises a support with a porous inorganic membrane disposed on the support. The inorganic membrane has an average thickness of from about 0.5 micron to about 30 microns, a porosity of from about 30% to about 65%, a median pore size (d50) of from about 0.01 micron to about 1 micron, and a value of (d90−d10)/d50 less than about 2, as measured by mercury porosimetry. An example of a support includes an inorganic porous support.
US10183234B2 Crossflow tray for a mass transfer column, mass transfer column and use of the mass transfer column
The invention relates to a crossflow tray for a mass transfer column (27) in which a gas is conducted in countercurrent to a liquid, the crossflow tray (1) having passage orifices (3) for the gas and at least two downcomers (5), the downcomers (5) projecting beyond the top surface of the crossflow tray (1) and a collecting cup (13) being disposed beneath each downcomer (5). The downcomer (5) projects into the collecting cup (13), the minimum horizontal cross-sectional area of the collecting cup (13) is 1.2 to 4 times greater than the horizontal cross-sectional area of the downcomer (5) at the outlet, and the collecting cup (13) has a circumferential wall (15) having an overflow (19).The invention further relates to a mass transfer column comprising the crossflow trays and to a use of the mass transfer column.
US10183229B2 Building toy
A building toy and a method of building with it. The toy is designed to be constructed of a rigid and generally non-deformable material such as, but not limited to, wood and particularly hardwood, and is constructed in the fashion of a log-style building toy. The toy utilizes interconnecting notches in its construction, but provides for a variety of specialized pieces which allow for interconnection of parts where there is one notch but not another, as well as the ability to build roofs, floors, and specialty structures such as fireplaces through the use of specialized components. Further, the use of more strongly connecting components allows for stronger structures to be built.
US10183225B2 Portable computer gaming control station
A portable gaming control station for holding a keyboard and mouse is disclosed, according to certain embodiments. The portable gaming control station comprises a rectangular tub with a mouse mat area, a keyboard compartment, a cable management compartment, and a built-in powered USB hub, according to certain embodiments.
US10183223B2 Systems and methods for providing virtual reality content in an online game
Virtual reality content in an online game may be provided by providing access to users attempting to join a game instance via virtual reality platforms and denying access to users attempting to join the game instance via non-virtual reality platforms. Virtual reality content in an online game may be provided by requiring users playing the online game via virtual reality platforms during a time period to achieve a first objective, and requiring users playing the online game via non-reality platforms during the time period to achieve a second objective. The first objective may require interaction with the virtual reality content and the second object may not require interaction with the virtual reality content. Virtual reality content in an online game may be provided by requiring all users to achieve an objective during a time period. The objective may require interaction with the virtual reality content.
US10183221B2 Game program, game control method, and computer
A computer-implemented method for operating a computer game. It can include identifying a playing user and one or more other users; storing user information about one or more other users and the game progress information of those other users; determining whether any of the other users satisfy a predetermined condition based on their game progress information; identifying any of the other users that meet the condition and qualify as substitution-target users; displaying the substitution-target users to the playing user; obtaining input from a playing user indicating the selection of at least one substitution-target user; allowing the user to play the game, and obtaining a result of a game played by a playing user on behalf of a substitution-target user, with said game being one available to the substitution-target user; and updating the game progress information of the substitution-target user in accordance with the result of that game.
US10183217B2 Hand-held controller using segmented capacitive touch trigger
A hand-held controller includes a handle extending in a longitudinal direction. The handle is shaped and dimensioned to be grasped by a user's hand. A trigger protrudes from an outer surface of the handle and moves relative to the handle responsive to pressing of the trigger by a finger of the user's hand. The trigger includes a touch surface that comes into contact with the finger of the user's hand to detect sliding of the finger of the user's hand on the touch surface.
US10183216B2 Game apparatus, storage medium, game controlling method and game system
A game apparatus includes a micon, and the micon measures step counts in correspondence with the magnitude of accelerations indicated by acceleration data from an acceleration sensor when a user carries the game apparatus in a sleep mode in which the apparatus is closed. The step counts are converted into earned coins. In each of a plurality of games executed by the game apparatus, by using the earned coins, a special item is purchased, playing in a special course is permitted, a hint is displayed, and a game is played in fast-forward.
US10183214B2 Table game multiplier system and method therefor
A table game multiplier system and method expands the play of a craps table by allowing a player to wager on a live-action craps table game being played at a table in a system operator, such as a casino or other suitable establishment, without requiring the person to be physically present at the craps table. The system allows the live-action craps table game to be virtually tiered or duplicated, thereby allowing a set of additional players to wager on a craps table identical to the one being played at a particular system operator. The additional players may connect to the table game multiplier system via an electronic telecommunication device such as, but not limited to, a smartphone, a tablet computer, or a personal computer, which may communicate with the system operator to allow the electronic placing of wagers on the tiered craps table.
US10183209B1 Storage device
A storage device includes at least one set of first and second tubular members, and a plurality of elastic cords that form a penetrable barrier. A first end of each elastic cord is coupled to a first tubular member by a knot, and a second end of each elastic cord is coupled to a second tubular member by positioning an enlarged body in a keyhole. A method for assembling a storage device includes securing first and second tubular members to a frame, looping an elastic cord around the first tubular member, and inserting an enlarged body into a keyhole of the second tubular member. In alternative example, each end of the elastic cord includes an enlarged body and each end of the elastic cord is positioned in a keyhole. In another alternative example, the first tubular member is fed through the loop of each elastic cord.
US10183208B2 Device for towing a board for board sports
The telescopic device for towing a board for board sports includes a base mounted on the board; and a skid with an in-use position positioned spaced apart from the base, and an out-of-use position positioned close to the base. There is a mechanism for mounting the skid so as to slide relative to the base between the in-use position and the out-of-use position and mechanism for retaining the skid in the in-use position, that includes part of the skid and an additional retaining device that is part of the mechanism for mounting the skid. The mechanism for retaining has an active position for holding the skid in the in-use position. The active position is intended for a movement stress, which is exerted on the skid in the direction of the out-of-use position. There is an inactive retaining position intended for a stress that is greater than a predetermined stress.
US10183205B2 Slip-proof grip sleeve and method for making the same
A slip-proof grip sleeve includes a lining tube and a slip-proof strip mounted on an outer periphery of the lining tube. The slip-proof strip includes a gripping portion between front and rear ends thereof. The slip-proof strip further includes a first folding portion adjacent to the rear end and a second folding portion adjacent to the gripping portion. The first and second folding portions are thinner than a thickness of the gripping portion. The first folding portion is folded toward an inner face of the slip-proof strip to overlap with the second folding portion. The slip-proof strip includes a third folding portion adjacent to the front end and a fourth folding portion adjacent to the gripping portion. The third and fourth folding portions are thinner than the thickness of the gripping portion. The third folding portion is folded toward the inner face to overlap with the fourth folding portion.
US10183204B2 Golf club insert
An insert for a golf club head, wherein the insert includes a generally planar base surface and a maximum thickness, Tmax, measured perpendicular to the base surface. The insert further includes a first component comprising a non-metallic material, and a second component coupled to the first component and comprising a continuous, formed metal sheet having a thickness between 0.01 mm and 3.0 mm, the second component extending a maximum distance, D, in a direction perpendicular to the base surface, that is no less than 6 mm. The insert is configured such that a ratio D/Tmax is no less than 0.50.
US10183200B2 Short game analysis system
The present invention generally relates to lightweight, portable robot for analyzing golf balls for short game performance attributes. The preferred robot is specifically designed to be lightweight and portable and to be able to hit a golf ball off of the ground or a mat that simulates the ground such that realistic short game performance can be evaluated.
US10183199B1 Tubular projectile device
Tubular projectile devices are disclosed herein. An exemplary tubular projectile device includes a spheroid frame having a long axis and a short axis. Further, the exemplary tubular projectile device includes a tubular medial section coupled with the spheroid frame; a first bicone comprising an exterior first cone congruent with an interior first cone, the first bicone being terminal along the long axis of the spheroid frame and coupled with the spheroid frame; and a second bicone comprising an exterior second cone congruent with an interior second cone, the second bicone being terminal along the long axis of the spheroid frame and coupled with the spheroid frame. The exemplary tubular projectile device may be a football.
US10183198B2 Golf ball compositions
Disclosed herein are polyurethane golf ball compositions. The compositions are prepared by adding a UV absorber to a polyol prior to reacting the polyol with an isocyanate to form a prepolymer, which is then reacted with a curing agent to form the polyurethane.
US10183192B2 Therapeutic hand-held exercise device
A therapeutic hand-held exercise device includes a pair of movable members that each define a handle portion and an end effector portion. The movable members are pivotably connected for relative pivotal movement between a first position and a second position. The handle portion of one of the movable members defines at least one flexible member engaging post. The end effector portion of the other movable member defines at least one flexible member engaging post such that the flexible member engaging posts can receive a common flexible member. The flexible member engaging posts are joined via a first common flexible member and other flexible member engaging posts are joined via a second common flexible member. The common flexible members may each exhibit a tensile strength that provides resistance to movement which either differs from or is equal to the tensile strength of the other common flexible member.
US10183185B2 Fall arrest apparatus
A fall arrest apparatus including a force damping subsystem having a damper, a brake release mechanism connected to the force damping subsystem and arranged to trigger when a force having a sufficient magnitude is transmitted to the brake release mechanism, and a brake mechanism including an energy storage device arranged to deploy at least one anchor when the brake release mechanism is triggered. The force is provided by a falling object to the force damping subsystem and the force damping subsystem is arranged to decelerate the falling object after the brake release mechanism is triggered.
US10183184B2 Closed circuit breathing apparatus and method of operating same
A closed circuit breathing apparatus (2) and a method of operating the same, the method comprising: determining whether a sufficient amount of replenishing gas is being supplied to a breathing circuit (4); sensing pressure within the breathing circuit (4) using a pressure sensor (6); generating a pressure signal representative of the sensed pressure; determining whether the pressure signal is representative of breathing; and generating an alert if it is determined that both an insufficient amount of replenishing gas, such as oxygen, is being supplied to the breathing circuit (4) and that the pressure signal is representative of breathing.
US10183183B2 Acoustic applicators for controlled thermal modification of tissue
An apparatus and method for modifying collagen containing dermal tissue. The apparatus includes a source of ultrasound energy comprised of a plurality of curvilinear ultrasound transducers shaped to direct ultrasound energy to selected skin depths. The transducers have variable curvature, drive frequency, power level and geometries to effect precise control of collagen modification.
US10183182B2 Methods and systems for treating plantar fascia
Various embodiments, described herein, provide methods and systems for the treatment of plantar fascia. In some embodiments, a method of non-invasive treatment of plantar fasciacan include the steps of identifying a damage location comprising a planter fascia; directing a conformal distribution of ultrasound energy to the plantar fascia at the damage location; creating a plurality of micro lesions in the plantar fascia at the damage location; initiating healing of a plurality of micro tears in the plantar fascia at the damage location; and sparing intervening tissue between the plantar fascia and a surface of a sole of a foot.
US10183181B2 Ion chamber for radiation measurement
An ion chamber has a chamber having an interior volume. There is a first electrode and a second electrode in the chamber and separated by a gap. A collector electrode is positioned between the first electrode and the second electrode. The collector electrode is shaped to occlude a portion of the first electrode from the second electrode.
US10183177B2 Patient monitor
Images obtained by a camera system (10) arranged to obtain stereoscopic images of a patient (20) undergoing radio-therapy are processed by a modeling unit (56,58) which generates a model of the surface of a patient (20) being monitored. Additionally the patient monitoring system processes image data not utilized to generate a model of the surface of a patient being monitored to determine further information concerning the treatment of the patient (20). Such additional data can comprise data identifying the relative location of the patient and a treatment apparatus (16). This can be facilitated by providing a number or retro-reflective markers (30-40) on a treatment apparatus (16) and a mechanical couch (18) used to position the patient (20) relative to the treatment apparatus (16) and monitoring the presence and location of the markers in the portions of the images obtained by the stereoscopic camera (10).
US10183175B2 Cancer detection and treatment apparatus
A catheter treatment apparatus comprises an elongate tubular member and an expandable support. The expandable support comprises a radioactive substance to treat cancerous tissue and is configured to expand from a narrow profile for insertion to a wide profile to engage and treat tissue remaining after resection. The expandable support can be sized to fit within a volume of removed tissue to place the radioactive substance in proximity to the capsule and remaining tissue, to spare the capsule and proximate nerves and vessels to treat tissue in proximity to the capsule. The elongate tubular member may comprise a channel such as a lumen to pass a bodily fluid such as urine when the expandable support engages the tissue to treat the patient for a plurality of days. The treatment apparatus can be used to resect and diagnose tissue concurrently. Based on the diagnosis, targeted segmental treatment may be given.
US10183174B2 Device for providing body temperature regulation and/or therapeutic light directed to vasculature
One bracelet embodiment provides therapeutic blood irradiation at a first wrist region using a first module, and body temperature regulation/irradiation at a second wrist region using a second module. A connector couples one end of the modules together, while an attachment band releasably couples the second ends together, for attachment to the wrist. The first module includes first and second distributed pluralities of lights respectively emitting 850 and 660 nm wavelengths, and a third plurality emitting 630 nm, 532 nm, and 450 nm wavelengths, positioned in a row substantially parallel to the arm of the user. The second module includes first and second rows of lights on first and second sides of a cooling unit, each emitting 405 nm wavelengths, with the two rows positioned for penetration to the radial and ulnar arteries. The bracelet includes a microprocessor, LED screen, and firmware for displaying a GUI permitting treatment protocol selections.
US10183173B2 Content output device, content output method, control device, and control method
There is provided a content output device including a selection unit which selects content according to a user's condition and a magnetic field pattern corresponding to the content, a content output unit which outputs the content, and a magnetic field generating unit which generates a magnetic field based on the magnetic field pattern.
US10183172B2 Monitoring and detecting magnetic stimulation
A method, system, and apparatus for monitoring a magnetic field related to magnetic stimulation may be provided. A system for monitoring a pulsing magnetic field related to magnetic stimulation therapy may include a magnetic stimulation component, a sensor, and a processor. The magnetic stimulation component may be configured to generate the pulsing magnetic field for the magnetic stimulation therapy. The sensor may be configured to generate a signal associated with the pulsing magnetic field. The processor may be configured to estimate a first characteristic associated with a first peak of the signal, estimate a second characteristic associated with a second peak of the signal, and determine a third characteristic of the signal based on the first characteristic and the second characteristic. The processor may be configured to determine whether a failure occurred based on the third characteristic of the signal.
US10183169B2 Systems and methods for facilitating selection of one or more vectors in a medical device
Systems and methods may facilitate selection of a vector for delivering electrical stimulation to a patient's heart. One illustrative method may include delivering electrical stimulation at a first voltage to each vector in a first set of two or more vectors of a multi-vector medical system, determining whether the delivered electrical stimulation at the first voltage resulted in capture for each of the vectors in the first set of two or more vectors, identifying those vectors of the first set of two or more vectors that were determined to result in capture as a second set of vectors, delivering electrical stimulation at a second voltage that is lower than the first voltage to each vector in the second set of vectors, and determining whether the delivered electrical stimulation at the second voltage resulted in capture for each of the vectors in the second set of vectors.
US10183168B2 Systems and methods for automated charge balancing of multiple electrodes for uninterrupted therapy and evoked response sensing
Electrical stimulation of a target (e.g., nervous tissue) is performed, wherein balance phases are automatically determined, and at least one of the electrodes is indirectly monitored during therapy delivery. The stimulation system is further configured to generate correction currents when a voltage accumulated at associated double layer capacitances crosses pre-defined thresholds so as to reduce or cancel the accumulated voltages without therapy interruption. A finer automatic determination of balance phases permits minimizing the stimulus artifact for evoked response sensing. Closed-loop neurostimulation may be performed based on such evoked responses.
US10183166B2 Systems and method for automatically detecting an MRI environment for patient implanted with medical device
Methods, medical devices, and magnetic resonance imaging (MRI) systems are provided. A patient implanted with a medical device is exposed to a time-varying magnetic field having a signature, thereby inducing mechanical vibrations in at least one component of the medical device. A vibrational characteristic of the mechanical vibrations induced in the component(s) is detected. The vibrational characteristic is analyzed, and the signature of the magnetic field is identified based on the analyzed vibrational characteristic. The medical device is automatically switched from a first operational mode to a second operational mode when the signature is identified.
US10183163B2 Systems and methods for delivering pulsed electric fields to skin tissue
Systems and methods for controlling a tissue of a subject using applied pulsed electric fields. The system for controlling a therapy provided to a tissue of a subject using applied pulsed electric fields. The system includes an electrode assembly configured to engage a skin tissue of a subject to deliver a series of electric field pulses to the skin tissue and a user input configured to receive an operational instruction for the series of electric field pulses. The operational instruction defines at least one of a pulse duration, a pulse frequency, a pulse number, and a pulse amplitude. The system also includes at least one processor configured to access the operational instruction received by the user input and, using the operational instruction, create an electric field profile to be generated by the electrode assembly about the skin tissue of the subject to control a fibroblast characteristic while preserving a vascular perfusion in at least a portion of the skin tissue. The processor is also caused to control the electrode assembly using the electric field profile to deliver the series of electric field pulses to control the fibroblast characteristic.
US10183160B2 Wearable therapeutic device
A wearable therapeutic device includes a garment configured to be worn on a torso of a patient. The garment has an anterior portion and a posterior portion. The garment is configured to house at least one defibrillator component, a first therapy electrode disposed in the anterior portion of the garment, a second therapy electrode disposed in the posterior portion of the garment, and an alarm module configured to alert the patient of an impending defibrillation shock from the at least one defibrillator component to be delivered by at least one of the first therapy electrode and the second therapy electrode. The first therapy electrode and the second therapy electrode are configured to be electrically coupled to the at least one defibrillator component. At least one of the first therapy electrode and the second therapy electrode is at least one of woven into the garment and comprises a textile material.
US10183158B2 Connecting structure for medical use
A connecting structure for medical use includes a first connecting portion 1 and a second connecting portion 2. The first connecting portion 1 includes a threadedly engageable portion 22a, a support portion 22b and a sealing portion 14. The second connecting portion 2 includes a threadedly engageable portion 2c and a sealing portion 2b. The threadedly engageable portions are threadedly engageable with each other. The sealing portions are joinable to each other by advancement of a threaded engagement between the threadedly engageable portions. An operating cylinder 30 is mounted on an outer periphery of the support portion 22b. A torque limiting mechanism 40 is disposed between the operating cylinder 30 and the support portion 22b. The sealing portions 14, 2b can be joined by turning the operating cylinder 30 in a threaded engagement advancing direction. When a rotary torque applied to the operating cylinder 30 reaches a predetermined torque as a result of a resistance generated by the joining of the sealing portions, the operating cylinder 30 is turned free from the support portion 22b. By this arrangement, appropriate sealing properties can be secured and the sealing portions can be prevented from breakages.
US10183155B2 Implantable devices and methods for evaluation of active agents
Devices for the local delivery of microdose amounts of one or more active agents, alone or in combination, in one or more dosages, to selected tissue of a patient are described. The devices generally include multiple microwells arranged on or within a support structure and contain one or more active agents, alone or in combination, in one or more dosages and/or release pharmacokinetics. In an exemplary embodiment, the device has a cylindrical shape, having symmetrical wells on the outside of the device, each well containing one or more drugs, at one or more concentrations, sized to permit placement using a catheter, cannula, or stylet. Optionally, the device has a guidewire, and fiber optics, sensors and/or interactive features such as remote accessibility to provide for in situ retrieval of information and modification of device release properties. In a preferred embodiment, the fiber optics and/or sensors are individually accessible to discrete wells.
US10183153B2 Sinus wall implant
An apparatus comprises an absorbent body, a non-permeable feature, and a port feature. The absorbent body comprises a wicking feature. The non-permeable feature is coupled with the absorbent body. The non-permeable feature and at least a portion of the absorbent body are configured to fit in an opening in a paranasal sinus wall. The port feature extends through the absorbent body. The port feature defines a lumen. The wicking feature extends outwardly relative to the port lumen. During installation of the apparatus, the non-permeable feature is positioned in an opening in the paranasal sinus wall. The absorbent body is oriented such that the wicking feature is in contact with mucosal tissue in a sinus cavity defined by the paranasal sinus wall. A proximal portion of the absorbent body is positioned outside the paranasal sinus wall.
US10183151B2 Reentry catheter and method thereof
The invention generally relates to method and apparatus for crossing an obstruction in a tubular member, and more particularly to a medical device method for crossing of a chronic occlusion in a subintimal or interstitial space of an artery.
US10183149B2 Five degree of freedom ultrasound catheter and catheter control handle
Catheter ultrasound systems including a sheath, a handle, a sheath lumen, and an ultrasound catheter disposed within the lumen of the sheath with ultrasound elements capable of visualizing anatomical regions. The handle allowing the ultrasound catheter to rotate with respect to the sheath using a rotation adjustment knob within the handle or alternatively an separate manipulation handle attached to the proximal end of the ultrasound catheter. The sheath, ultrasound catheter, or both may also include one or more electrodes or other location sensor for both orienting the ultrasound element as well as for diagnostic purposes.
US10183145B2 Enhanced flexibility neurovascular catheter
A catheter is provided, such as for distal neurovascular access or aspiration. The catheter includes an elongate flexible body, having a proximal end, a distal end and a side wall defining a central lumen. A distal zone of the side wall includes a tubular inner liner, a tie layer separated from the lumen by the inner liner, a helical coil surrounding the tie layer, adjacent windings of the coil spaced progressively further apart in the distal direction. An outer jacket surrounds the helical coil. The outer jacket is formed from a plurality of tubular segments positioned end to end, coaxially about the coil. The flexural load profile of the catheter as a function of catheter length is configured to provide enhanced distal flexibility while maintaining high backup support.
US10183141B2 Systems and methods for treating dementia
The present disclosure provides systems and methods for at least one of preventing, reducing, and treating a level of or change in at least one of amyloid-β (Aβ) peptide, C-terminal fragment-β (β-CTF), β-secretase (BACE1), γ-secretase, neuroinflammation, and/or dementia (e.g., Alzheimer's disease or age-related decline) in a subject by inducing synchronized gamma oscillations in the brain of the subject using, for example, a stimulus-emitting device to emit a stimulus (e.g., light, sound, and/or haptic) at a frequency (e.g., about 40 Hz) that synchronously activates in vivo a specific cell type (e.g., fast-spiking-parvalbumin (FS-PV) immunoreactive interneurons) and/or brain region (e.g., a sensory cortex and/or hippocampus) of the subject.
US10183138B2 Interchangeable mask assembly
A system of breathing arrangements for delivering breathable gas to a patient includes at least first and second cushion components, e.g., full-face, nasal, nasal prongs, nose tip, and/or a combination of any of the above, including a nasal or full-face cushion and nasal prongs/nozzles combination, etc., that are different from one another in at least one aspect, and a common frame assembly configured to support each of the first and second cushion components. Various embodiments are directed to a full-face or nasal mask used with a frame having lateral connector portions having a stiffening member. The mask assembly may include a nose height adjustment device for the height of the cushion, or a cushion adjustment member by which the position of the cushion may be adjusted relative to the frame. The mask assembly may include a chin strap assembly.
US10183132B2 Methods and devices for co-delivery of liquid and powdered hemostats and sealants
The present invention is directed to an integrated delivery device that is operable with one hand and provides co-delivery of a liquid medicant and a powder medicant onto a tissue or wound from a liquid medicant expression subunit and a powder medicant expression subunit. Each expression subunit having an actuator for the liquid medicant and the powder medicant contained therein that are positioned in close proximity to one other at a proximate end of said expression subunits and delivery cannulas for each of said expression subunits that positioned in close proximity to one other at a distal end of said expression subunits. The present invention also relates to method for using such integrated devices.
US10183130B2 Measuring valve health by pressure monitoring
A medical fluid infusion system includes a pump system configured to deliver a fluid drug to a patient. The system includes a pump, such as a piston pump, for driving fluid to a patient. One or more pressure sensors are configured to measure and detect changes in fluid pressure in a fluid flow line of the infusion system. The changes in fluid pressure, when detected, can be an indication of proper or improper functioning of a valve system of the pump system of the fluid infusion system.
US10183123B2 Needle protection device
Injection device of fluid product (100) comprising a syringe body (101) and a needle (110) fixed in an axial end projection (102) of the syringe body, said end projection (102) comprising an axial end surface (103), said injection device comprising a needle protection device (200), said protection device being, in a storage position, fixed on said injection device, said protection device being removable from said injection device, said protection device comprising an inner body (210) made of substantially supple and/or deformable material and an outer body (220) made of substantially rigid material, said inner body (210), in a storage position, sealingly closing the distribution orifice (111) of said needle (110) and sealingly cooperating with said injection device (100), and said outer body (220) comprising a fixing part (228) which, in a storage position, cooperates with a shoulder (104) of said injection device (100) for fixing said protection device (200) on said injection device (100), said inner body (210) comprising a proximal axial end edge (213) adapted, in a storage position, to sealingly cooperate with the syringe body (101) only with said axial end surface (103), said inner body (210) being made of material having the following properties: a hardness greater than 55 Shore A, in particular greater than 60 Shore A, an elasticity greater than 8 MPa, in particular greater than 10 MPa, a compression set less than 30%, in particular less than 25%, a density greater than 1, in particular greater than 1.3.
US10183120B2 Dose measurement systems and methods
Embodiments described herein generally relate to devices, systems and methods for measuring a volume or number of doses remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a light guide disposed and configured to reflect electromagnetic radiation toward the container. The dose measurement system also includes a light guide disposed and configured to emit electromagnetic radiation into the light guide. A plurality of sensors are located in the apparatus that are optically coupleable to the light guide and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light guide. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors. The processing unit is further operable to convert the received data into a signature representative of the electromagnetic radiation detected by the plurality of sensors.
US10183106B2 Blood purification system
A blood purification system includes a plurality of monitoring devices (1) each attached to a dialyzer (5) to perform a blood purification treatment on a patient. A dialysate supplying device (2) supplies a dialysate to each of the monitoring devices (1). The plurality of monitoring devices (1) and the dialysate supplying device (2) are connected to each other by a LAN cable α. Thus, predetermined individual information relating to the plurality of monitoring devices (1) is transmitted from each of the monitoring devices (1) to the dialysate supplying device (2).
US10183101B2 Liposuction device and use thereof
Embodiments of the present invention disclose a device for removing adipose tissue, comprising a self-contained syringe device comprising an inner syringe included within an outer syringe and wherein a filter is attached inside the outer syringe barrel; wherein the filter comprises a filter material that prevents premature filter collapse where the filter material is optionally coated to increase stiffness, and wherein liposuctioned adipose tissue is collected and purified inside the syringes. Methods of using the devices or system are also disclosed.
US10183100B2 Flow control system
A flow control system may include an inner nosecone having an inner nosecone distal end and an inner nosecone proximal end, an outer nosecone having an outer nosecone distal end and an outer nosecone proximal end, an aperture of the outer nosecone, a gasket having a gasket distal end and a gasket proximal end, a gasket aperture of the gasket, a gasket seal of the gasket, a flow control mechanism having a flow control mechanism distal end and a flow control mechanism proximal end, and a control aperture of the flow control mechanism. A rotation of the flow control mechanism about the gasket may be configured to decrease an aspiration flow rate. A rotation of the flow control mechanism about the gasket may be configured to increase an aspiration flow rate.
US10183099B2 Antimicrobial and antifouling catechol-containing polycarbonates for medical applications
Catechol-bearing polycarbonates (catechol polymers) were prepared comprising i) a catechol repeat unit comprising a side chain catechol group, ii) a cationic repeat unit comprising a side chain cationic group selected from the group consisting of quaternary amine groups, quaternary phosphine groups, and combinations thereof, and iii) a PEG repeat unit comprising a side chain poly(ethylene oxide) group having a degree of polymerization of about 5 to about 30. The catechol polymers form antimicrobial and antifouling films on a variety of substrate surfaces, in particular silicone rubber.
US10183097B2 Engineered cardiac derived compositions and methods of use
The present invention establishes a new standard for investigative studies of patient-specific, genetic cardiac diseases at a functional, tissue level by creating a novel platform for the study of cardiac related diseases, including cardiac conduction dysfunction, arrhythmias and depressed contractility for example. Provided herein are novel compositions of human engineered heart slices (EHS) formed from thin slices of decellularized cardiac tissue. Also included are compositions comprising a hybrid of decellularized tissue and organotypic organ slice technology. Intact mammalian hearts are precision cut to obtain thin slices in a range of thicknesses, decellularized, and seeded with various mammalian cells which can be from a variety of sources. Methods of investigation of many diseases and methods of use of these compositions for screening compounds for therapeutic purposes are also provided.
US10183096B2 Valve treatment by injection
A method for treating a valve of a heart of a subject is provided. The method includes inserting a needle into the heart, and, using the needle, injecting a soft-tissue-filling material into an annulus of the valve. Other embodiments are also described.
US10183090B2 Clean room autoclave bag and hopper cover system
A cleanroom autoclave system including a reusable autoclave breather bag and a reusable fill line hopper cover. The autoclave bag is formed from a launderable abrasion resistant inner fabric layer and a launderable polyester outer fabric layer, and has a zipper closure. The hopper cover is formed from a circular bonnet and an open tubular skirt formed from a launderable polyester fabric, and includes an elastic portion and snaps to secure the hopper cover.
US10183086B2 Footwear sanitizing system
Introducing ultraviolet (UV) light to interior portions of footwear alters the environment inside a shoe or other footwear to destroy microorganisms or inhibit their growth. Visible light can also be used to prevent further microorganism growth. Introducing forced air flow through the footwear removes dampness in and thereby deodorizes the footwear. A preferred embodiment comprises an adjustable shoe tree equipped with a UV germicidal light source and electronic safeguards that prevent appreciable leakage of UV radiation outside the shoe.
US10183083B2 Metal mesh, sterilization determination method, and cleaning determination method
A metal mesh has a plurality of through-holes. A photosensitive organic material is attached to at least part of the metal mesh. The metal mesh is sterilized and/or cleaned. A determination of whether or not the sterilization and/or cleaning has been successful is made by analyzing the photosensitive organic material attached to the metal mesh.
US10183075B2 Trace elements
The invention discloses a trace element solution, which comprises at least one metal selected from the group comprising selenium, copper, zinc, manganese and chromium and which comprises a concentration of the metal(s) of at least 60 mg/ml. The solution further comprises at least one compound selected from the group comprising iodine, potassium iodide, sodium iodide, iron, iron chloride, zinc oxide, manganese sulphate, sodium selenite, copper carbonate, sodium carbonate, anhydrous disodium EDTA and sodium hydroxide. The trace element solution is prepared by a method consisting essentially of the steps of preparing a MnCO3 mixture in a container; adding an EDTA/NaOH mixture to the container and subsequently adding at least one metal compound; and adding Na2SeO3 to the container to obtain the trace element solution. The method also comprises the step of adding CrCl3.6H2O to the trace element solution.
US10183074B2 Cationic oil-in-water emulsions
This invention generally relates to cationic oil-in-water emulsions that contain high concentrations of cationic lipids and have a defined oil:lipid ratio. The cationic lipid can interact with the negatively charged molecule thereby anchoring the molecule to the emulsion particles. The cationic emulsions described herein are useful for delivering negatively charged molecules, such as nucleic acid molecules to cells, and for formulating nucleic acid-based vaccines.
US10183071B2 Interaction of moraxella catarrhalis with epithellal cells, extracellular matrix proteins and the complement system
The present disclosure relates to surface proteins of Moraxella catarrhalis and their ability to interact with epithelial cells via cell-associated fibronectin and laminin, and also to their ability to inhibit the complement system. These surface proteins are useful in the preparation of vaccines. The present disclosure also provides peptides interacting with fibronectin, laminin and the complement system.
US10183067B1 TAA/CD4OL composition/vaccine for malaria
Provided are compositions and methods of selecting at least three fragments one each from three domains of the malarial CSP for generating antigen specific CD8 effector T cells and non-cross reacting neutralizing antibody immune responses to the malarial parasite, which when administered prevent an infection of a human being when bitten by a malaria infected mosquito. The composition and method comprises priming an individual by administering a mixture of one or more adenoviral expression vectors encoding one or more fusion proteins, which comprises the malarial CSP antigen fragments linked to the extracellular domain of the CD40 ligand. The adenoviral expression vector comprises a transcription unit encoding a secretable fusion protein, the fusion protein containing selected malarial sporozoite CSP antigen fragments linked to the CD40 ligand to block the attachment to or infection of the human liver cell(s) by the malarial sporozoite.
US10183064B2 Delivery system comprising a proteolytic enzyme or effector thereof for use in a method for oral treatment and uses thereof
The present disclosure provides a delivery system comprising (i) a physiologically acceptable carrier and (ii) a proteolytic enzyme or effector thereof for use in a method for relaxing fibers within a subject's oral cavity. In some embodiments, the relaxation is for use in tooth manipulation (particularly repositioning). In some embodiments, the method involves the use of the proteolytic enzyme or effector thereof at a concentration effective to cause relaxation of fibers between the tooth's alveolar bone and gingiva while maintaining integrity of the fibers surrounding the tooth. Also disclosed herein are methods for fiber relaxation and/or repositioning of tooth making use of the proteolytic enzyme or effector thereof.
US10183063B2 Injection composition comprising hyaluronidase for removal of topical fat
The present invention relates to an injection composition comprising hyaluronidase for topical fat reduction. More particularly, the present invention relates to an injection composition comprising 300 IU to 600 IU of hyaluronidase and a local anesthetic, an antihistamine, a lipolysis stimulator and a collagen production stimulator. The present invention promotes the reduction of topical fat tissue, thereby improving obesity and helping weight loss and maintenance of body shape while preventing side effects or skin imbalance by the even removal of fat. Further, at the same time, the present invention can achieve a skin lifting effect where skin resilience is maintained by the stimulation of collagen production.
US10183060B2 Compositions and methods for adjoining type I and type II extracellular domains as heterologous chimeric proteins
The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
US10183057B2 Use of liposomal WNT composition to enhance osseointegration
Methods and compositions are provided for the therapeutic use of Wnt proteins, for enhancing bone growth and regeneration, including repair following injury, osseointegration of implants, and the like. In some embodiments of the invention, the compositions are administered locally, e.g. by injection at the site of an injury. For certain conditions it is desirable to provide Wnt activity for short periods of time, and an effective dose will be administered over a defined, short period of time.
US10183052B2 Mutant tomatoes and use thereof for preventing weight gain and/or treating obesity-related conditions
The invention relates to the use of tomatoes for inhibition, amelioration or prevention of adipogenesis mediated diseases such as obesity, lipid storage disease and hyperlipemia. Provided is a tomato plant, fruit, fragment or extract thereof for use in a method for preventing weight gain, and/or inhibiting, preventing or ameliorating a disease condition associated with adipogenesis in a mammal, wherein the tomato is a ripening-impaired mutant tomato, such as a ripening inhibitor (rin), nonripening (nor), and/or never ripe (Nr) gene mutant tomato. Also provided are anti-adipogenic extracts and compositions comprising the extract.
US10183051B2 Personal care compositions with improved hyposensitivity
The present invention provides personal care compositions comprising a carrier and a mixture of essential oil components having specific levels of eucalyptol, terpene materials and auxiliary fragrance materials. The compositions herein gentle to skin and have a fragrance and activity similar if the composition were made using the pure extracted essential oil.
US10183046B2 Porcine lactic acid bacterial strains
A first aspect of the invention relates to a porcine lactic acid bacterial strain, wherein said bacterial strain is characterised by one or more of the following characteristics: (i) the ability to exhibit antimicrobial activity against E. coli; (ii) the ability to exhibit antimicrobial activity against S. enteritidis; (iii) the ability to suppress inflammation in IPEC cells induced by 12-0-tetradecaboylphorbol-13-acetate (PMA); (iv) the ability to block the attachment or invasion of IPEC cells by S. enteritidis; (v) the ability to block the attachment or invasion of IPEC cells by E. coli; (vi) the absence of antibiotic resistance to one or more antibiotics selected from the following: ampicillin; cefotaxime; chloramphenicol; erythromycin; gentamicin; tetracycline; vancomycin; metronizadole; nalidixic acid; and kanamycin; and (vii) the ability to exhibit heat stability when subjected to three cycles of heating, each cycle comprising heating at a temperature of 70° C. for a period of 15 minutes. Further aspects of the invention relate to compositions comprising said bacterial strains, and therapeutic uses of said bacterial strains.
US10183045B2 Human-derived bacteria that induce proliferation or accumulation of regulatory T cells
Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
US10183044B2 Systems and methods for thrombosis prevention
The disclosure provides a composition for inhibiting thrombosis. The composition includes 5 to 25% by weight of Fish Oil, 15 to 55% by weight of Willow Bark Extract, and 0.2 to 5% by weight of Vitamin E.
US10183043B2 Combined organ and hematopoietic cells for transplantation tolerance of grafts
Methods and compositions are provided for combined transplantation of a solid organ and hematopoietic cells to a recipient, where tolerance to the graft is established through development of a persistent mixed chimerism. An individual with persistent mixed chimerism, usually for a period of at least six months, is able to withdraw from the use of immunosuppressive drugs after a period of time sufficient to establish tolerance.
US10183040B2 Method for regulation of lipid metabolism
Provided is a method for regulation of lipid metabolism comprising a step of administering to a subject in need thereof a therapeutically amount of pharmaceuticals. The pharmaceuticals comprise an effective amount of a composition containing a ferrous amino acid chelate and pharmaceutically acceptable carriers to regulate lipid metabolism. The amino acid is capable of being chelated with the ferrous iron in a chelated state stably as passing through a stomach. The composition containing the ferrous amino acid chelate can effectively control the variances of body weight and enhance metabolism of body fat of a subject. The pharmaceuticals prepared by the composition containing the ferrous amino acid chelate have effects on regulation of lipid metabolism.
US10183037B2 Nucleoside phosphoramidate prodrugs
Disclosed herein are phosphoramidate prodrugs of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomer, salt (acid or basic addition salt), hydrate, solvate, or crystalline form thereof, represented by the following structure: Also disclosed are methods of treatment, uses, and processes for preparing each of which utilize the compound represented by formula I.
US10183035B2 Etoposide and prodrugs thereof for use in targeting cancer stem cells
The present invention pertains to the use of podophyllotoxin derivatives, such as CAP7.1, in methods for inhibition of and/or prevention of the growth and/or survival of cancer stem cells. The invention discloses the surprisingly specific activity of the compounds in accordance with the invention against a cancer stem cell population. In this respect the present invention provides the use of the compounds as described in the treatment of cancer, specifically of cancers which have a high risk of developing metastases, chemotherapeutic resistances and/or cancer relapse. Provided are novel methods of cancer treatment, and pharmaceutical compositions comprising the compounds as described, for use in such treatment methods.
US10183032B2 Methods for treating bacterial infection
The present disclosure relates to molecules that function as selective modulators (i.e., inhibitors and agonists) of the Ras-homologous (Rho) family of small GTPases and, in particular, CDC42 GTPase, and their use to treat bacterial infection including systemic infection from sources such as Staphylococcus aureus and Streptococcus pyogenes.
US10183028B2 Enrichment method of ergosterol peroxide from sporoderm-broken Ganoderma lucidum spore powder
The invention provides an enrichment method of Ergosterol peroxide from sporoderm-broken Ganoderma lucidum spore powder, comprising the steps of preparing crude extract containing Ergosterol peroxide, purification by medium pressure preparative chromatography, purification by simulated moving-bed, and recrystallization. The operation of this invention is simple and stable, with higher yield and low cost, suitable for industrial-scale production.
US10183027B2 Lanthanide toolbox for multi-modal, non-invasive tumor specific theranostic prodrugs
The present disclosure relates to theranostic prodrugs with responsive signals in-vitro or in-vivo and uses thereof. It also relates to synthesized europium complexes for evaluating the binding with integrin αvβ3.
US10183024B2 Crystalline forms of ibrutinib
The present invention provides crystalline forms of Ibrutinib. Specific crystalline forms provided by the present invention include Ibrutinib Form APO-I, an anhydrous form; APO-II, a methyl benzoate solvate of Ibrutinib; and APO-IV, a methyl salicylate solvate of Ibrutinib.
US10183023B2 Uses
The subject matter generally relates to methods of treatment and/or prophylaxis of CNS diseases, disorders, and/or injuries. In one aspect, the subject matter relates to inhibitors of phosphodiesterase 1 (PDE1) as neuroprotective agents and/or neural regenerative agents. In a further aspect, the subject matter relates to individuals that are at risk for the development of CNS disease or disorder.
US10183021B2 sGC stimulators
Compounds of Formulae I′ and I are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.
US10183019B2 Treatment of cancer with dihydropyrazino-pyrazines
Provided herein are methods for treating or preventing glioblastoma multiforme (GBM) characterized by O6-methylguanine-DNA methyltransferase (MGMT) expression and/or promoter methylation status, comprising administering an effective amount of a Dihydropyrazino-Pyrazine Compound to a patient having glioblastoma multiforme (GBM) characterized by O6-methylguanine-DNA methyltransferase (MGMT) expression and/or promoter methylation status.
US10183012B2 Compounds and compositions and methods of use
Described herein are compounds useful in the modulation of blood uric acid levels, formulations containing them and methods of using them. In some embodiments, the compounds described herein are used in the treatment or prevention of disorders related to aberrant levels of uric acid.
US10183011B2 Anti-depression compounds
This technology relates generally to compounds and methods for stimulating neurogenesis (e.g., post-natal neurogenesis, including post-natal hippocampal and hypothalamic neurogenesis) and/or protecting neuronal cell from cell death. Various compounds are disclosed herein. In vivo activity tests suggest that these compounds may have therapeutic benefits in neuropsychiatric and/or neurodegenerative diseases such as schizophrenia, major depression, bipolar disorder, normal aging, epilepsy, traumatic brain injury, post-traumatic stress disorder, Parkinson's disease, Alzheimer's disease, Down syndrome, spinocerebellar ataxia, amyotrophic lateral sclerosis, Huntington's disease, stroke, radiation therapy, chronic stress, abuse of a neuro-active drug, retinal degeneration, spinal cord injury, peripheral nerve injury, physiological weight loss associated with various conditions, as well as cognitive decline associated with normal aging, chemotherapy, and the like.
US10183010B2 2-oxo-1,2-dihydrobenzo[cd]indole compound and use thereof
The present invention relates to the technical field of medicinal chemistry, and in particular discloses a 2-oxo-1,2-dihydrobenzo[cd]indole compound and use thereof. The compound and pharmaceutically acceptable salt, isomer, racemate, prodrug, co-crystallized complex, hydrate, and solvate thereof can effectively inhibit the BET bromodomain receptor, and can be used for preparing a medicine for treating cancers, cell proliferative disorders, inflammatory diseases, and autoimmune disorders, sepsis, and viral infections.
US10183008B2 Treatment of prolonged status epilepticus
Methods for terminating, preventing, and/or treating status epilepticus are generally provided. The method can include administering a prophylactically or therapeutically effective amount of stiripentol or a related compound thereof to an individual in need of treatment of status epilepticus. The individual can be in need of treatment of prolonged status epilepticus, refractory status epilepticus, and/or benzodiazepine-resistant status epilepticus.
US10183007B2 Method of producing proanthocyanidin oligomer
The present invention relates to a composition containing as its main component proanthocyanidin oligomer to which a substance having a phloroglucinol ring structure or resorcinol ring structure has been bonded and reduced in the molecular weight, which is obtained by heating plant materials containing proanthocyanidin polymer or extract thereof with a substance having a phloroglucinol ring structure or resorcinol ring structure in an acidic aqueous solution, production method thereof, and uses of the composition in health products and pharmaceutical products. According to the invention, proanthocyanidin oligomer having physiological activity, to which a substance having a phloroglucinol ring structure or resorcinol ring structure has been bonded and reduced in the molecular weight to such a level that the oligomer can be absorbed into living body, which has been conventionally difficult to obtain at high yield from plant raw materials, can be produced efficiently and easily.
US10183006B2 Methods of therapeutic monitoring of nitrogen scavenging drugs
The present disclosure provides methods for evaluating daily ammonia exposure based on a single fasting ammonia blood level measurement, as well as methods that utilize this technique to adjust the dosage of a nitrogen scavenging drug, determine whether to administer a nitrogen scavenging drug, and treat nitrogen retention disorders.
US10183003B2 Methods of therapeutic monitoring of nitrogen scavenging drugs
The present disclosure provides methods for evaluating daily ammonia exposure based on a single fasting ammonia blood level measurement, as well as methods that utilize this technique to adjust the dosage of a nitrogen scavenging drug, determine whether to administer a nitrogen scavenging drug, and treat nitrogen retention disorders.
US10182997B2 Liposomal curcumin for treatment of cancer
The present invention provides a compositions and methods for the treatment of cancer, including pancreatic cancer, breast cancer and melanoma, in a human patient. The methods and compositions of the present invention employ curcumin or a curcumin analog encapsulated in a colloidal drug delivery system, preferably a liposomal drug delivery system. Suitable colloidal drug delivery systems also include nanoparticles, nanocapsules, microparticles or block copolymer micelles. The colloidal drug delivery system encapsulating curcumin or a curcumin analog is administered parenterally in a pharmaceutically acceptable carrier.