| Document | Document Title |
|---|---|
| US10076712B2 |
Systems and methods for fluid delivery in seat systems
The present invention relates to systems and methods of delivering fluid from one or more armrests of seat systems. In a feature, the system includes a seat support assembly with armrests with one or more fluid nozzles mounted on one or more of the armrests, a fluid delivery system coupled to the one or more fluid nozzle(s), wherein the fluid nozzles are mounted on an end of the armrest that slopes upward to direct fluid toward the viewer. In another feature, the system includes a seat support assembly with air outlet(s) on an armrest coupled to a fan, which reduces the load on the fluid delivery system. In another feature, the system includes a controller (e.g., a network server) configured to communicate on and off commands that correspond to events on a timeline of a movie to actuate the fluid delivery system to deliver fluids to the outlets. |
| US10076710B2 |
Portable apparatus and method for playing interactive games via portable apparatus
A method for playing interactive games via a portable apparatus is disclosed. The method is applied to a portable apparatus. The method includes: transmitting a location signal; receiving location signals transmitted from other portable apparatuses; receiving a shooting signal; and determining a game status based on the shooting signal. |
| US10076707B2 |
Video game with dynamic quest clues based on number of completions
A game system including a server device connected to a network and one or more terminal devices operated by users and executing a video game that a player character plays a quest in a game space which has a quest data storing unit which stores quest data, a playing status storing unit which stores playing status of the quest, a quest control unit which permits the start of the quest and a hint control unit which notifies the information for the starting conditions. The playing status storing unit acquires the playing status from the quest control unit and updates the playing status, and the hint control unit determines the information for the starting conditions based on the playing status. |
| US10076704B2 |
Game device
In such a timing game that a user taps on a collision position at a time when fore ends of a line object 51A and a line object 51B (hereinafter line objects 51) collide, a background image in perspective is displayed as if moving in depth direction. Simultaneously, the line objects 51 are moved corresponding to the background image. Therefore, it is possible to display the line objects 51 as if moving in depth direction, so that it is possible to provide the timing game with sense of speed. |
| US10076698B2 |
Automated or assisted umpiring of baseball game using computer vision
Methods and systems for use in automating or assisting umpiring of a baseball or softball game are described herein. A location of a strike zone is determined based on video images of a batter standing next to home plate captured by a camera. Locations of a ball traveling towards the batter, and locations of the bat being held by the batter, are autonomously tracked using computer vision based on video images captured by at least two cameras having different positions. Additionally, there are autonomous determinations of whether a location of the ball intersects with the strike zone, and whether the batter made a genuine attempt to swing the bat at the ball, and based one at least one of these determinations, there is an autonomous determination of whether a “strike” or a “ball” occurred. Additionally, an indication of whether a “strike” or a “ball” occurred is autonomously output. |
| US10076696B2 |
Method for providing swim-in-place functionality in a bathing unit system and control system implementing same
A method and a system are described for operating a bathing unit system to provide swim-in-place functionality to a swimmer. A communication link is established between the bathing unit system and an auxiliary device worn by or implanted in the body of the swimmer. A signal conveying information associated with the swimmer and originating from the auxiliary device is received. Control signals for controlling operational settings associated with a propulsion assembly of the bathing unit system are derived at least in part by processing the information conveyed by the signal originating from the auxiliary device. The control signals are then released to control the operational settings associated with the propulsion assembly. In another aspect, a graphic display is provided presenting the user with a customized set of selectable swim-in-place configurations derived at least in part by processing a signal originating from an auxiliary device worn by or implanted in the body of the swimmer. |
| US10076695B1 |
Hockey rebounder, slide board
A hockey training device is provided. The training device includes a substantially flat sheet with a smooth upper surface. The present invention includes a plurality of elastic band suspended to the upper surface. A first vertical post and a second vertical post may be attached to the flat sheet so that the elastic band is secured about the first and second vertical posts. The elastic band includes a front surface facing towards a center portion of the flat sheet. Therefore, a puck may be passed towards the elastic band and the elastic band rebounds the puck towards the user. The device may be used to train both backhand and forehand shooting and pucks skills. Further, the device may be used to train a sliding skating motion in a skating training mode. |
| US10076692B2 |
Set of golf clubs
A set of golf clubs including golf club heads having improved mass distribution characteristics. The set includes golf club heads having a club head main body including a hitting face, a muscle back shell and a weight insert disposed in the muscle back shell. The golf club heads have relatively low blade length while maintaining high moment of inertia. |
| US10076690B2 |
Golf club head with adjustable center of gravity
A golf club head comprising a slidable weight for adjusting the location of the club head center of gravity is disclosed herein. The club head has a channel disposed in its sole and a slidable weight assembly comprising a weight body and a rotatable cam portion. The channel includes a single, L-shaped rail extending upwards from a channel floor, and the slidable weight assembly is reversibly fixed to the rail when the rotatable cam portion is rotated such that a curved protrusion is disposed underneath a ledge of the L-shaped rail. The channel preferably has an S-shaped or closed loop configuration such that the club head's center of gravity can be adjusted along X (front to back) and Y (heel to toe) horizontal axes. |
| US10076684B2 |
Multi-layer core golf ball
Low compression golf balls comprising a multi-layer core and a cover are disclosed. The multi-layer core comprises at least three layers, including at least one thermoset layer and at least one thermoplastic layer. |
| US10076679B2 |
Weightlifting plates
Weightlifting plates might be constructed of various materials. For example, a density-adjustable composition might be used that allows respective weight amounts plates to differ, while the plate volumes remain consistent. As such, in a set of weightlifting plates, each plate in the set includes a common volume (e.g., diameter and thickness) and a different respective weight amount. In addition, the weight plates can be combined with a barbell. |
| US10076674B2 |
Apparatus and method to visually view high-dose-radiation apparatus used to verify quality assurance
An apparatus for testing a high-dose-rate afterloader machine comprising an image capturing device that used to capture a plurality of still images or a real-time video, wherein said image capturing device further comprises, a zoom lens, a microphone and a light, a measurement ruler that is located on a base plate; a plurality of calibration points located on the said base plate, a source insert that connects to said high-dose-rate afterloader machine to one end, wherein said source insert allows entry of a radioactive pellet and a source wire into one end, and an adjustable shaft that is connected to said base plate and connected to said image capturing device. |
| US10076673B2 |
Interactive dose gradient based optimization technique to control IMRT delivery complexity
A method for dose-gradient based optimization of an intensity modulated radiation therapy plan. First, an optimizer (6) performs a first optimization (40) of the plan to generate dose distributions corresponding to the plan. Next, the optimizer (6) generates a beam specific dose gradient map (42) for each beam of the plan. Then, new dose gradients are specified (44) for the plan. Last, the optimizer (6) performs a final optimization (46) using the new dose gradients. The final optimization is given the new dose gradients as soft constraints into an objective function. The optimizer (3) applies a limiting factor to the objective function such that a first dose gradient is limited by the optimizer only if the first dose gradient exceeds the new dose gradient for a specific beamlet. |
| US10076671B2 |
Apparatus for retina phototherapy
A process for using a retinal photostimulation device involves limiting multiple or repeated uses of the device during a particular treatment cycle. Ordinarily a physician would not want to repeat multiple photostimulation treatments on a patient in a short period time. The process would prevent such retreatment during a single treatment cycle where the retina for any subsequent treatment biometrically matches the retina for an earlier treatment. Such subsequent treatments would be permitted within a predefined period of time after the earlier treatment. Such subsequent treatment may also be permitted where the retinas do not biometrically match. |
| US10076665B2 |
Devices for controlling spinal cord modulation for inhibiting pain, and associated systems and methods, including controllers for automated parameter selection
Devices for controlling spinal cord modulation for inhibiting pain, and associated systems and methods, including controllers for automated parameter selection are disclosed. A particular embodiment includes receiving a first input corresponding to a location of a signal delivery device implanted in a patient, establishing a positional relationship between the signal delivery device and an anatomical feature of the patient, receiving a second input corresponding to a medical indication of the patient, and, based at least in part on the positional relationship and the indication, automatically identifying a signal delivery parameter in accordance with which a pulsed electrical signal is delivered to the patient via the signal delivery device. |
| US10076663B2 |
Systems and methods for the treatment of pain through neural fiber stimulation
Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith. |
| US10076662B2 |
Portable one-piece therapeutical apparatus with dual heating and low-frequency treatment functions
A portable one-piece therapeutical apparatus with dual heating and low-frequency treatment functions includes a main unit having an accommodating space and a patch portion; a control means installed in the accommodating space and including a printed circuit board assembly with an operating component for controlling low-frequency pulses and a heating operation, an electrical connector installed at the front of the printed circuit board assembly for charging a battery and reading, writing and transmitting data; at least one heating means installed at the main unit and electrically coupled to the printed circuit board assembly for producing a heating effect; at least one low-frequency electrode layer disposed under the patch portion and electrically coupled to the printed circuit board assembly for transmitting low-frequency pulses; and a battery installed in the accommodating space and directly and electrically coupled to the printed circuit board assembly for supplying power to the patch therapeutical apparatus. |
| US10076657B2 |
Lead end having slotted member
Various embodiments of this disclosure concern a lead end containing a slotted member. A slotted member can have a plurality of slots extending along at least a portion of the length of the slotted member, each of the slots having a respective positioning feature, the plurality of slots having a plurality of positioning features at different longitudinal positions along the length of the slotted member. The lead end can further include a plurality of conductors at least partially within the plurality of slots, each slot of the plurality of slots containing at least a respective one of the plurality of conductors, the plurality of conductors electrically connecting exposed electrical elements of both ends of the lead. |
| US10076655B2 |
Vestibular stimulation system
A vestibular stimulation system and method that includes a housing, a power supply disposed in the housing, an electrode assembly adapted to be coupled to the housing, and a controller disposed in the housing and operatively coupled to the power supply. The controller controls the delivery of energy from the power supply to the electrode assembly. An input element is also disposed on an exterior surface of the housing. The input element is manually manipulated to control the operation of the vestibular stimulation system. A display disposed on an exterior surface of the housing provides visual information regarding the operation of the vestibular stimulation system. A mounting assembly is coupled to the housing to mount the housing on such a user. |
| US10076650B2 |
Enhanced stylet for drug depot injector
A pellet delivery system is provided that comprises a needle having an inner surface defining a passageway. The needle has a first portion that extends along a longitudinal axis and a curved second portion comprising an opening that is in communication with the passageway. The second portion extends transverse to the longitudinal axis. A pellet is positioned in the passageway. A plunger is slidably positioned in the passageway. The plunger comprises a shaft having a rounded tip configured to push the pellet through the first and second portions and out of the opening without the pellet becoming stuck within the passageway or the opening. Implants, systems, constructs, instruments and methods are disclosed. |
| US10076649B2 |
Delivery system for hollow microneedle arrays
Systems and methods for delivering microneedles to a patient's skin are described. In one aspect, a system for delivering a microneedle array to a patient's skin surface is provided. The system includes a delivery apparatus with a housing, and an infusion device detachably received in the housing. |
| US10076644B2 |
Method and apparatus for treating urethral stricture
A method of treating a treatment area of a body lumen includes inserting an elongated member into the body lumen, wherein the elongated member is configured to guide a delivery member, the delivery member possessing an outer portion with a treatment part, moving the delivery member to the treatment area, applying the treatment part to the treatment area, and withdrawing the delivery member from the treatment area. |
| US10076643B2 |
Pressure regulating buoyant valve for a shunt system
A gravitational pressure regulating valve to regulate fluid flow of a patient, including a fluid chamber having an inlet port to receive a bodily fluid and an outlet port to discharge received bodily fluid, the fluid chamber including a first chamber configured to capture a non-buoyant member therein and to guide the non-buoyant member along a longitudinal axis of the first chamber to facilitate bi-directional reciprocating movement of the non-buoyant member to and from the inlet port, and a second chamber configured to capture one or more buoyant members therein such that when the second chamber is filled with bodily fluid, at least one of the buoyant members applies a resolved buoyant pressure from a buoyant force of the one or more buoyant members in opposition to an inlet pressure of fluid at the inlet port. |
| US10076640B2 |
Torque device
A device for manipulating a wire includes a first structure and a second structure pivotably mounted with respect to each other so as to define respective facing surfaces configured for alternating between a closed position and at least one open position, where each of the respective facing surfaces includes one or more detent elements and one or more tooth elements extending therefrom. In the device, the tooth elements of the first structure and the second structure are in an interlocking and overlapping arrangement in at least the closed position. Further, each of the tooth elements has a concave surface for defining a passage between the facing surface in the at least one open position. Additionally, each of the detent elements is arranged to face the concave surface of one of the tooth elements of an opposite one of the respective facing surfaces in the closed position. |
| US10076631B2 |
Medical cabin system and method for using the same
A medical cabin system comprises a safety protection structure, an identification structure, an environment simulation structure, a radiotherapy isolation structure, and one or more other independent walls. The safety protection structure is disposed on an entrance of the medical cabin system. The identification structure is disposed on a medical equipment of the medical cabin system or in an enclosed space defined by a stereo location region of the medical cabin system. The environment simulation structure is disposed on a top portion and at least one side wall of the medical cabin system. The radiotherapy isolation structure isolates the stereo location region from a radiotherapy region of the medical cabin system. The independent walls define at least one enclosed space with the radiotherapy isolation structure. |
| US10076624B2 |
Flexible structure for mask, and method and apparatus for evaluating performance of a mask in use
Headgear for a respiratory mask assembly includes at least one strap. The at least one strap includes one or more bladders filled with a gel. |
| US10076623B2 |
Endotracheal cuff and technique for using the same
An inflatable balloon cuff may be adapted to seal a patient's trachea when associated with an endotracheal tube. Configurations of these cuffs that include tapered regions with certain characteristics, such as cuff wall diameter and thickness, may provide improved sealing of the trachea. |
| US10076622B2 |
Single lung/lobe ventilation endotracheal tube
Techniques for single lung ventilation (SLV) include a hollow main tube with outer diameter sized to fit inside a bronchus of a patient. The length of the main tube is sufficient for a distal end of the main tube to reach a first side bronchus from a proximal end configured to be located in a vicinity of a mouth of the patient. The hollow main tube has a ventilating orifice separated from the distal end at a location that corresponds to a different second side bronchus. A hollow tubular sleeve is moveably disposed inside and longitudinally aligned with the main tube. The sleeve is configured to be positioned in at least two positions: a first position that does not block the ventilating orifice; and, a second position that does block the ventilating orifice. |
| US10076621B2 |
Method and system for displaying information on life support systems
Methods and systems for displaying information on life support systems (LSS) are provided. One LSS includes a patient monitoring portion configured to acquire, as LSS information, patient measurement information from a monitored patient. The LSS also includes a communication device configured to communicate with a remote device to obtain, as non-LSS information, information acquired by the remote device. The LSS further includes a display configured to display a user interface that presents the non-LSS information. |
| US10076619B2 |
Vent arrangement for respiratory mask
A control system provides automated control of gas washout of a patient interface, such as a mask or nasal prongs. A gas washout vent assembly of the system may include a variable exhaust area, such as one defined by gears, radial exhaust revolvers and/or flow diverters for a conduit having a variable gas passage channel. The vent assembly may be attached substantially near or included with the patient interface. An actuator of the assembly, such as a solenoid, motor or voice coil, manipulates the vent assembly. The actuator may be configured for control by a processor to change the exhaust area of the vent assembly based on various methodologies including, for example, sleep detection, disordered breathing event detection and/or leak detection. |
| US10076615B2 |
Nasal delivery
A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a nosepiece for fitting to a nostril of a subject, wherein the nosepiece comprises a tip element which includes a delivery aperture from which substance is in use delivered into the nasal cavity, and the tip element is at least in part tapered such as to be inclined to a longitudinal axis of the nosepiece, with the delivery aperture extending both laterally across the tip element and along a longitudinal extent of the tip element; a nozzle through which substance is in use delivered, preferably substantially axially to a longitudinal axis of the nosepiece, to the respective nasal cavity; and a delivery unit for delivering substance through the nozzle of the nosepiece. |
| US10076605B2 |
Drug delivery device with needle actuation mechanism
A delivery unit (2) of a drug delivery device (1), the delivery unit (2) comprising a subcutaneous delivery mechanism (9) having a subcutaneous delivery member (92), and a subcutaneous delivery member actuation mechanism (10) being operable to move the subcutaneous delivery member (92) between a retracted position and an extended position. The actuation mechanism (10) comprises a rotary member (102) having an engagement member (104) rotatable relative a support member (14), and an actuator (106) comprising a pivot portion (10A) and an engagement portion (10B) pivotally connected to the support member via the pivot portion. The engagement member (104) and engagement portion (10B) are configured to engage upon rotation of the rotary member to pivot the actuator between first and second positions and to thereby move the subcutaneous delivery member (92) between the corresponding retracted and extended positions. In an embodiment, the needle actuation mechanism may comprise a reuse protection. |
| US10076604B2 |
Pump for medical purposes
A medical fluid pump, comprising a first, inner fluid system including a motor-driven suction/pressure unit and a first fluid pressure chamber which can be filled with fluid and emptied by the suction/pressure unit, and a second, outer fluid system including a second fluid pressure chamber which is coupled to the first pressure chamber in a pressure- and/or volume-dynamic manner via a movable separating wall and which is alternately coupled—via a valve means of the second fluid system—to a suction line and pressure line depending on the current working phase of the suction/pressure unit of the first fluid system is disclosed. |
| US10076603B2 |
Syringe packaging system including oxygen absorber
A syringe packaging system that includes a packaging member defining a first compartment, a second compartment, and a third compartment that are in gaseous communication theretogether is disclosed. The first compartment is structured to receive a syringe barrel therein, the second compartment is structured to receive a plunger rod therein, and the third compartment is structured to receive an oxygen absorber therein. With the packaging member enclosing the syringe barrel, the plunger rod, and the oxygen absorber, the oxygen absorber is adapted to draw oxygen from within the syringe barrel and to absorb oxygen contained within at least one of the first compartment, the second compartment, and the third compartment of the packaging member. The syringe packaging system of the present disclosure also allows for reduced storage space of a syringe assembly. |
| US10076601B2 |
Implanted tube and external interface for saline or drug delivery to the paranasal sinuses
An embodiment in accordance with the present invention provides an implanted catheter and an external device that the patient uses to inject a therapeutic into the implanted tube. The implanted catheter can be equipped with a fixation mechanism that secures the catheter in place and eases physician insertion and removal. The fixation mechanism can include shape memory arms having silicone tips or can be a second catheter branch configured to hold the device in the user's sinus cavity. The catheter can also include numerous exit holes to prevent obstruction and deliver the therapeutic. An interface between the implanted catheter and the external device is incorporated, to ensure a reliable seal for medication passage. A method and device for delivery of the catheter to the correct position can also be included. |
| US10076595B2 |
Systems and methods for blood recovery from absorbent surgical materials
Systems and methods are described for salvaging red blood cells from patients during a surgical procedure. In one general aspect, a system is described for extracting blood from blood-soaked absorbent surgical materials such as surgical sponges, gauze, tape, and the like. The collected blood and fluids from these materials can be transferred to a cell salvage machine for harvesting viable red blood cells for autotransfusion. |
| US10076590B2 |
Modified starch material of biocompatible hemostasis
A modified starch material for biocompatible hemostasis, biocompatible adhesion prevention, tissue healing promotion, absorbable surgical wound sealing and tissue bonding, when applied as a biocompatible modified starch to the tissue of animals. The modified starch material produces hemostasis, reduces bleeding of the wound, extravasation of blood and tissue exudation, preserves the wound surface or the wound in relative wetness or dryness, inhibits the growth of bacteria and inflammatory response, minimizes tissue inflammation, and relieves patient pain. Any excess modified starch not involved in hemostatic activity is readily dissolved and rinsed away through saline irrigation during operation. After treatment of surgical wounds, combat wounds, trauma and emergency wounds, the modified starch hemostatic material is rapidly absorbed by the body without the complications associated with gauze and bandage removal. |
| US10076589B2 |
Biodegradable medical device having an adjustable degradation rate and methods of making the same
Disclosed herein are biodegradable medical devices comprising biodegradable materials (e.g., magnesium-calcium alloys) having an adjustable rate of degradation that can be used in various applications including, but not limited to, drug delivery applications, cardiovascular applications, and orthopedic applications to make biodegradable and biocompatible devices. Also disclosed herein are methods of making biodegradable medical devices comprising biodegradable materials by using, for instance, hybrid dry cutting/hydrostatic burnishing. |
| US10076585B2 |
Method of delivering a dose of a fluid composition from a microfluidic delivery cartridge
Microfluidic delivery systems and methods for dispensing a fluid composition into the air comprising microfluidic die and at least one heating element that is configured to receive an electrical signal comprising a certain on-time and wave form to deliver a fluid composition into the air. |
| US10076584B2 |
Low odor latex paint capable of reducing interior odors
A paint composition, which in some embodiments, has a low odor in the container, while during after application to a surface, and once the paint has dried on a surface is disclosed. A method of making such a paint composition is disclosed. A paint composition and method are also disclosed which include using a paint to control certain odors in interior rooms. |
| US10076583B2 |
Phase-stable, sprayable freshening compositions comprising suspended particles and methods of freshening the air or a surface with the same
A freshening composition is provided. The freshening composition includes a plurality of particles, a structurant system, and an aqueous carrier. The composition has a spray shear viscosity, as measured according to the SPRAY SHEAR VISCOSITY TEST METHOD described herein, of less than about 0.025 Pa-s. The composition has a creep recovery ratio of at least about 0.1, as measured according to the CREEP RECOVERY RATIO TEST METHOD described herein, or a yield stress of greater than 0 Pa and less than 1.0 Pa, as measured by the YIELD STRESS TEST METHOD described herein. |
| US10076582B1 |
Baby feeding product sterilization device and methods
A portable baby bottle sterilization device includes a housing having disposed therein an inner lining defining a bottle sterilization cavity, wherein the bottle sterilization cavity includes an opening, and wherein the inner lining is configured to receive one or more baby bottles therein through the opening, a power source, a plurality of UV LEDs coupled to the power source and to the inner lining, wherein the plurality of UV LED configured to provide UV-C light within the bottle sterilization cavity, and a processor coupled to the power source and to the plurality of UV LEDs, wherein the processor is configured to control intensity and duration of the UV-C light within the bottle sterilization cavity, and a cover coupled to the housing, wherein the cover is repositionable relative to the housing, wherein the cover can be positioned to removably cover the opening of the bottle sterilization cavity. |
| US10076576B2 |
Minimally toxic prodrugs
The present invention relates to the field of oligopeptide prodrugs that are intended for the treatment of cancer. The selectivity of these prodrugs requires the presence of an (oligo)peptidic moiety and/or a protective capping group to ensure the prodrug stability in blood. It further in particular relates to the exemplary oligopeptidic moiety ALGP and to prodrugs comprising it. In particular it also relates to the capping group phosphonoacetyl and to prodrugs comprising this capping group. |
| US10076575B2 |
Peptide, complex of peptide and siRNA and use thereof
A series of peptides and a peptide-siRNA complex are disclosed, wherein the peptide based complex effectively enhances delivery of siRNA molecules into the cells and release of siRNA in the cell, and improves siRNA mediated gene silencing efficiency of cellular targets. Pharmaceutical compositions that include the complex, as well as a use of the complex in the gene therapy field, are also disclosed. |
| US10076574B2 |
Methods, systems and compositions relating to cell conversion via protein-induced in-vivo cell reprogramming
Methods for treating a subject in need thereof are provided which include administering a pharmaceutical composition comprising a protein transduction reagent-modified reprogramming protein to the subject, wherein the protein transduction reagent is non-covalently bound to the reprogramming protein and wherein the protein transduction reagent comprises a cation reagent and a lipid. According to aspects, such methods provide delivery of protein-transduction reagent-modified reprogramming proteins to cancer cells, such as tumor cells, as well as diseased cells of diseased tissues and provide in vivo conversion of diseased cells into normal cells via protein-induced in situ cell reprogramming without administration of nucleic acids to the subject. |
| US10076572B2 |
Photodynamic therapy for treating Clostridium difficile infection using chitosan and tetracycline
Effective Photodynamic therapy (PDT) against C. difficile is provided using a composition including chitosan and tetracycline. |
| US10076563B2 |
Bordetella pertussis immunogenic vaccine compositions
This invention is directed to composition, vaccines, tools and methods in the treatment and prevention of Bordetella pertussis. In particular, the invention is directed to a three-pronged approach that involves removal of the nonessential vaccine components, use of a nondenatured, genetically detoxified mutant, and adding virulence factors. |
| US10076558B2 |
Prophylactic normalization of cutaneous wound repair
The present invention relates to methods of inhibiting scar formation in a skin wound as well as methods of promoting tissue regeneration in a skin wound in a subject in need thereof comprising administering in or near said wound an effective amount of one or more neurotoxins. |
| US10076547B2 |
Gene-modified coxsackievirus
A modified coxsackievirus showing improved safety and/or aggressiveness to be used for oncolytic virotherapy is provided. A modified coxsackievirus showing tissue-specific suppression of proliferation and comprising a mutated genome consisting of the genome of coxsackievirus B3 wild-type (CVB3-WT) inserted with at least one polynucleotide consisting of a target sequence of tissue-specific microRNA (miRNA) is provided. The mutated genome is preferably further inserted with the region encoding GM-CSF in an expressible form. |
| US10076546B2 |
Network-based microbial compositions and methods
Provided are therapeutic compositions containing combinations of bacteria, for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract of a mammalian subject, and methods for use thereof. |
| US10076542B2 |
Combined organ and hematopoietic cells for transplantation tolerance of grafts
Methods and compositions are provided for combined transplantation of a solid organ and hematopoietic cells to a recipient, where tolerance to the graft is established through development of a persistent mixed chimerism. An individual with persistent mixed chimerism, usually for a period of at least six months, is able to withdraw from the use of immunosuppressive drugs after a period of time sufficient to establish tolerance. |
| US10076538B2 |
Compositions comprising citrate and applications thereof
In one aspect, methods of promoting bone growth are described herein. In some embodiments, a method of promoting bone growth described herein comprises promoting cell differentiation or phenotype progression in a population of bone cells by providing a citrate-presenting composition to the population of bone cells. In some embodiments, the citrate-presenting composition is provided to the bone cells at a first stage of cell development selected to obtain a first cell differentiation or phenotype progression. Additionally, in some cases, a second citrate-presenting composition is further provided to the bone cells at a second stage of cell development selected to obtain a second cell differentiation or phenotype progression. |
| US10076533B2 |
Acyclic nucleoside phosphonate diesters
The present disclosure relates, inter alia, to compositions and methods for treating viral diseases and cancer. There are disclosed lipophilic antiviral and anticancer acyclic nucleoside phosphonate diesters, preparation thereof, and methods of using the compounds to treat viral diseases and cancer. |
| US10076523B2 |
HSPC-sparing treatments for RB-positive abnormal cellular proliferation
This invention is in the area of improved compounds for and methods of treating selected RB-positive cancers and other Rb-positive abnormal cellular proliferative disorders while minimizing the deleterious effects on healthy cells, for example healthy Hematopoietic Stem Cells and Progenitor Cells (HSPCs), associated with current treatment modalities. In one aspect, improved treatment of select RB-positive cancers is disclosed using specific compounds disclosed herein. In certain embodiments, the compounds described herein act as highly selective and, in certain embodiments, short, transiently-acting cyclin-dependent kinase 4/6 (CDK 4/6) inhibitors when administered to subjects. |
| US10076522B2 |
Systems and methods for treating bacterial infection
Therapeutic methods, kits, dosing regimens and uses as medicament are provided, for example, for the treatment of bacterial infection. The therapeutic methods can comprise intravenously administering to a subject who has a bacterial infection a pharmaceutical composition comprising a fixed amount of iclaprim. The administration of the fixed amount can achieve a Cmax(ss) below about 800 ng/mL, a T>MIC of between about 30% to about 95% and a ratio of AUC/MIC of about 20 to about 85, and the bacterial infection can be treated. The fixed amount can be about 70 mg to about 100 mg. The pharmaceutical composition can be infused into the subject about 1 to about 3 times a day daily over a time period of about 0.75 hours to about 4 hours. |
| US10076519B2 |
Substituted pyridazines as skeletal muscle modulators
Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and m are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof.Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof. |
| US10076515B2 |
Ophthalmic Composition
Provided herein is an ophthalmic composition. In some embodiments, the ophthalmic composition includes a low concentration of an ophthalmic agent for treatment of an ophthalmic disorder or condition; and an ophthalmically acceptable carrier, wherein the ophthalmic agent is distributed with substantial uniformity throughout the ophthalmically acceptable carrier. Further disclosed herein include an ophthalmic composition including a low concentration of an ophthalmic agent and deuterated water. Also disclosed herein are methods of arresting or preventing myopia development by administering to an eye of an individual in need thereof an effective amount of an ophthalmic composition as described herein. |
| US10076514B2 |
Methods of treating fabry disease in patients having the G9331A mutation in the GLA gene
Provided are methods of treating a patient diagnosed with Fabry disease and methods of enhancing α-galactosidase A in a patient diagnosed with or suspected of having Fabry disease. Certain methods comprise administering to a patient a therapeutically effective dose of a pharmacological chaperone for α-galactosidase A, wherein the patient has a splice site mutation in intron 4 of the nucleic acid sequence encoding α-galactosidase A. Also described are uses of pharmacological chaperones for the treatment of Fabry disease and compositions for use in the treatment of Fabry disease. |
| US10076512B2 |
Treatment of hepatitis delta virus infection
Methods of reducing hepatitis delta virus (HDV) viral loads in a patient are provided. In some embodiments, the method comprises treating the patient with lonafarnib-ritonavir co-therapy. In some embodiments, the method further comprises treating the patient with an interferon. |
| US10076511B2 |
Bisamide derivative of dicarboxylic acid as an agent for stimulating tissue regeneration and recovery of diminished tissue function
The invention relates to the field of medicine and concerns an agent that stimulates tissue regeneration and the recovery of diminished tissue and organ function. A medicinal agent for the treatment and/or prophylaxis of a pathological condition selected from the group including metabolic syndrome, impaired glucose tolerance, hepatitis, particularly chronic hepatitis and toxic hepatitis, idiopathic pulmonary fibrosis (IPF), emphysema of the lungs, chronic obstructive pulmonary disease (COPD) and cachexia, particularly as a result of impaired glucose tolerance, pulmonary fibrosis, chronic obstructive pulmonary disease, cancer and other diseases, is proposed in the form of an agent based on Treamide. The latter is a bisamide derivative of dicarboxylic acid of formula (I) or a pharmaceutically acceptable salt thereof. |
| US10076502B2 |
Transdermal therapeutic system for administering rivastigmine or derivatives thereof
The present invention relates to a transdermal therapeutic system for administering an active substance through the skin, comprising: a) a cover layer, b) a reservoir present on the cover layer, comprising a polymer matrix comprising the active substance, c) an adhesive layer present on the reservoir comprising a contact adhesive, and d) a removable layer present on the adhesive layer, the active substance being rivastigmine, a physiologically compatible salt, hydrate, solvate or derivative thereof, characterized in that the polymer matrix of the reservoir comprises neither hydroxyl groups nor carboxyl groups. |
| US10076499B2 |
Tamper resistant dosage forms
The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof. |
| US10076491B2 |
Vaccine composition
The invention provides a vaccine composition containing an antigen for inducing cellular immunity, comprising at least one first cellular immunity induction promoter. |
| US10076486B2 |
Gel-like hair-setting agent
The present invention relates to a silicon dioxide-containing cosmetic composition for hair setting or for the temporary reshaping of keratinic fibers, in particular human hair, which depending on the use enables both a matte and a shiny look and which after application to the hair enables shaping and restructuring of the hairstyle for a long period of time and furthermore forms no visible residues. |
| US10076483B2 |
Steroid carboxylic acid esters, compositions containing steroid carboxylic acid esters, and use of said compositions in local topical applications for cosmetic or dermatological purposes
The invention relates to the use of a steroid-3-carboxylic acid ester, a steroid-4 carboxylic acid ester or a steroid-17 carboxylic acid ester of a steroid, selected from the group of androstanones, androst-4-ene-diones, androst-5-ene-diones, dehydroepiandrosterones, androstenetriones or testosterones, with an acyl group of the carboxylic acid ester where R is selected from alkyl with at least two carbon atoms or cycloalkyl, or with the use of a compound containing these steroid carboxylic acid esters for local topical application for cosmetic or dermatological purposes. Moreover, this invention also relates to steroid carboxylic acid esters and their compounds used for local topical application. |
| US10076482B2 |
Soft solid oil-in-water emulsion comprising a mixture of nonionic surfactants, a water-soluble polysaccharide and a wax comprising at least one ester
The present invention relates to a composition in the form of an oil-in-water emulsion, comprising, in a cosmetically acceptable medium: A) a continuous aqueous phase and B) an oily phase dispersed in the said aqueous phase and comprising at least one hydrocarbon-based oil; C) at least one mixture consisting of: i) at least one nonionic surfactant containing a saturated linear hydrocarbon-based chain comprising at least 16 carbon atoms, the said surfactant being other than a fatty alcohol, and ii) at least one fatty alcohol chosen from: —a pure fatty alcohol comprising more than 16 carbon atoms; —a mixture consisting exclusively of fatty alcohols containing at least 16 carbon atoms and comprising at least 50% by weight of fatty alcohol containing at least 18 atoms relative to the weight of the fatty alcohol mixture; and D) at least one wax with a melting point of greater than 45° C. comprising one or more C40-C70 ester compounds and not comprising any C20-C39 ester compounds, in an amount from 1 to 10% by weight relative to the total weight of the composition and E) at least one water-soluble polysaccharide; the said composition having a hardness measured at 32° C. and at a humidity of 40% ranging from 20 kPa to 200 kPa and preferably ranging from 25 kPa to 150 kPa. The present invention also relates to a cosmetic process for treating and/or caring for human keratin materials, characterized in that it consists in applying to the surface of the keratin material a composition as defined previously. The present invention also relates to a cosmetic process for treating human perspiration and/or perspiration-related body odor, which consists in applying to the surface of a human keratin material a composition as defined previously comprising at least one deodorant active agent and/or one antiperspirant active agent. |
| US10076481B2 |
Compositions for treating periodontitis and dental calculus accumulation
Compositions comprising serine and an organic mono- or multi-phosphate salt and methods of using such compositions to treat and/or prevent periodontal disease and/or dental calculus are provided. |
| US10076480B2 |
Wet skin moisturizer product
A wet skin moisturizer (WSM) composition, in the form of an oil-in-water emulsion, contains the following components: a cationic emulsifier (such as behentrimonium chloride), a skin conditioner component (such as behenamidopropyl dimethylamine), and a block copolymer which comprises at least one segment derived from a thermoplastic monomer chosen from thermoplastic monomers, thermoplastic comonomers and mixtures thereof (such as a mixture of ethylene/propylene/styrene copolymer and butylene/ethylene/styrene copolymer). This composition is applied to previously-wetted skin following a shower or bath, after which the moisturized skin is dried. The composition blends nicely with the water on the skin to provide an even film that does not feel greasy on the skin and which provides the skin with hydration and skin conditioning benefits. |
| US10076477B2 |
Aerosol compositions having improved active ingredient application
The present invention relates to aerosol compositions for body care, comprising:a) at least one propellant, andb) a composition A, which comprises (i) at least one perspiration-inhibiting antiperspirant active ingredient, (ii) at least one hydrophobized clay material, and (iii) propylene carbonate, wherein the weight ratio of the propylene carbonate (iii) to the hydrophobized clay material (ii) is 1.75:1.00 to 2.00:1.00. The invention furthermore relates to the cosmetic use of a mixture of propylene carbonate (iii) and at least one hydrophobized clay material (ii) at a weight ratio of (iii):(ii) of 1.75:1.00 to 2.00:1.00 in antiperspirant aerosol compositions for improving the delivery rate of the antiperspirant active ingredient(s) when sprayed onto the skin, and to a cosmetic, non-therapeutic method for reducing or masking body odor in which an aerosol composition according to the invention is sprayed onto the skin. |
| US10076476B2 |
Oral care compositions comprising a peroxide source, a polyhydric alcohol, and a surfactant
Provided is an oral care composition comprising a peroxide source, a polyhydric alcohol and a surfactant system having an HLB value of from 4 to 13, wherein the combined amount of the polyhydric alcohol and the surfactant system is from 60 weight % to 95 weight % by total weight of the composition, and wherein the weight ratio of the polyhydric alcohol to the surfactant system is from 9:1 to 1:4. The composition is resistant to peroxide decomposition. |
| US10076475B2 |
Shell-structured particles for sunscreen applications
Shell-structured particles for sunscreen applications are provided herein. A method includes selecting one or more particles to serve as a core material in a sunscreen composition, wherein each of the one or more particles comprises a band gap within a predetermined range, and wherein said selecting is based on a desired absorption spectrum of the sunscreen composition; coating the one or more particles with at least one layer of zinc oxide. A composition includes selecting one or more particles to serve as a coating layer in a sunscreen composition, wherein each of the one or more particles comprises a band gap within a predetermined range, and wherein said selecting is based on a desired absorption spectrum of the sunscreen composition; and coating one or more zinc oxide particles with the one or more selected particles. |
| US10076473B2 |
Apparatus and method for manufacturing dried gel sheet and gel sheet or beauty pack manufactured by the same
The present invention provides a dried gel sheet manufacturing apparatus and method, and a gel sheet. The dried gel sheet manufacturing apparatus includes an applying unit 2 which includes gravure rolls 22a and 22b to apply a hydrogel composition of a reserving tank 24 on a supporting member M which is conveyed together with a lower film Fa to form a sheet shaped hydrogel H, a cooling drying unit 4 which cools the sheet shaped hydrogel H using a cooling plate 44 to be solidified while being transported; and a heating drying unit 6 which dries and irons the solidified sheet shaped hydrogel by a combination of a heater roll group 64 and a nozzle unit 66 or the nozzle unit 66, a dry conveyer 68, a godet roller 70 or a nozzle unit 66, a dry conveyer 68, a heater roll group 64, or a nozzle unit 66 and a godet roller 70 to obtain a gel sheet G2. Further, a dried gel sheet manufacturing method through the apparatus includes an applying step of forming a sheet shaped hydrogel H by a lower film Fa and protecting the sheet shaped hydrogel by adhering the upper film Fb on a top surface; a cooling drying step of passing the sheet shaped hydrogel H at a low temperature atmosphere to be solidified, and a heating drying step of receiving and separating the upper and lower films Fb and Fa from the sheet shaped hydrogel H which is solidified by the cooling and heating and drying the front and rear surfaces by ironing the sheet shaped hydrogel to collect the gel sheet S2. Through the manufacturing method, a gel sheet G2 which is formed to be a film so that density of the front and rear surfaces is higher than a center portion and a beauty pack obtained by pressing the gel sheet S2 by the mask member MP are suggested. |
| US10076471B2 |
Antimicrobial denture
A denture containing a henna powder or a henna extract, each of which comes from pulverized henna leaves and may include any of lawsone, tannic acid, and 2-methoxy-1,4-napthoquinone and a denture fabrication material. A denture containing at least one first antimicrobial ingredient selected from the group consisting of henna powder or a henna extract, lawsone, tannic acid, and 2-methoxy-1,4-napthoquinone, and a second antimicrobial ingredient, and optionally, a biocompatible gel and an odor neutralizer. |
| US10076469B2 |
Tube management system
A tube management system has a tube receiving element, a base element, and attachment elements extending from the base element. The tube receiving element is provided with a gripping element that functions to prevent tube migration. The attachment elements are provided within openings for receiving a device which is used to secure the tube management system to a patient. |
| US10076468B2 |
Medication dispenser bracelet with vibrating alarm and bluetooth communication
The present invention is a bracelet that contains a cartridge holding a plurality of interior storage compartments that are each designed to hold one or more pills. A sliding door is used to withdraw the pills from any one compartment at a time. The bracelet comprises electronic components that enable it to activate a vibrating alarm at a prearranged time to remind the user to take her pills, and to track when the door has been opened to withdraw the pills, and to communicate the alarm and tracking information to an external electronic device, such as a mobile phone, via Bluetooth wireless communication. |
| US10076466B2 |
Timed sequence indicators
A containment system for packaging a plurality of products that are to be accessed in a predetermined sequence. The containment system includes a plurality of product compartments that each holds at least one of the plurality of products. Indicators having a gas reactive material that changes appearance after a predetermined period of time of exposure to ambient air are deployed when gas cover seals are removed or broken to access a product in the product compartment. |
| US10076465B2 |
Systems, methods, and kits for cleansing an ocular region
Systems, methods, and kits useful for cleansing the eyelids and maintaining eyelid hygiene are disclosed. In one embodiment, a system for treating or cleansing an ocular region is disclosed. The system consists essentially of: (A) a tubular applicator, wherein the applicator comprises: (i) a first chamber and a second chamber; and (ii) a sealable element situated between the first chamber and the second chamber, wherein at least the second chamber is substantially pre-filled with an ocular composition, and (B) a dispenser, wherein the dispenser is bonded to an external surface of a first end of the applicator. |
| US10076464B2 |
External ear canal pressure regulation system
An external ear canal pressure regulation device including a fluid flow generator and an earpiece having a first axial earpiece conduit fluidicly coupled to the fluid flow generator, whereby the earpiece has a compliant earpiece external surface configured to sealably engage an external ear canal as a barrier between an external ear canal pressure and an ambient pressure. |
| US10076463B2 |
Vibrating electromechanical device for female stimulation
This disclosure relates to devices and method for producing stimulation to the clitoris of a user. In certain aspects, the vibrator device includes a vibrator mechanism and a body enclosing the vibrator mechanism. The body includes a first side member and a second side member. During use, the first side member and second side member are configured to engage in an interference fit with labia such that the body is in contact with a clitoris without obstructing the vaginal opening. |
| US10076461B2 |
Apparatus for training dynamic balance and turning manoeuvres during walking
The object of the invention is an apparatus suited for individuals in training dynamic balance and turning maneuvers while walking, said apparatus allowing said maneuvers while an individual is standing, walking on a flat surface or walking on a treadmill that can rotate around a vertical axis of the treadmill. To serve this purpose, the apparatus of the invention is provided with a base platform (1), in which two universal joints (2,2′) are arranged that are connected with a pelvis element (5) with two vertical rods (3,3′) or vertically adjustable rods (30,30′) via conventional spherical joints (4,4′), and the universal joints (2,2′) have two degrees of freedom that can further be provided by drives (6,7,8). |
| US10076456B2 |
Mobile chair apparatus comprising foot pedals
A mobile chair apparatus is described that comprises a drive assembly that preferably includes one or more moveable foot pedals, and drive wheels which rotate in response to rotation of the foot pedals by the mobile chair occupant, and a steering assembly which comprises two steering wheels and at least one tiller, configured such that forward and backward movement of said tiller will translate into movement of both steering wheels, wherein the drive assembly and the steering assembly concurrently enable the mobile chair occupant to propel and steer the mobile chair apparatus without assistance from another person. |
| US10076454B2 |
Absorbent article with waistband
A disposable absorbent article is disclosed that includes a first waist region, a second waist region, a crotch region disposed between the first waist region and second waist region, a waist edge in the first waist region, at least one waistband in the first waist region adjacent the waist edge, and at least one fastener in the second waist region, wherein the first waist region has a resiliency of greater than about 5 mJ and a stiffness of less than about 10 N. |
| US10076452B2 |
Tampon pledget for increased bypass leakage protection
There is provided a tampon pledget that includes one or more enhanced features that result in the pledget exhibiting increased bypass leakage prevention. These enhanced features may include, but are not limited to, geometry, absorption, and any combinations thereof. There is also provided one or more methods for constructing a tampon pledget having increased bypass leakage protection. |
| US10076450B2 |
Structured film containing beta-nucleating agent and method of making the same
A structured film of a semi-crystalline polyolefin and a beta-nucleating agent is disclosed. The structured film has a backing and upstanding posts attached to the backing. At least a portion of the film typically includes beta-spherulites. In some embodiments, the backing is microporous while the upstanding posts have lower porosity. A method of making a structured film is also disclosed. The method includes extruding a melt of a polyolefin and a beta-nucleating agent in the presence of a tool to provide the structured film having upstanding posts on a backing and cooling at least a portion of the structured film to a temperature sufficient to form beta-spherulites. In some embodiments, the method further includes stretching the structured film containing beta-spherulites to provide micropores in the backing. |
| US10076449B2 |
Wound dressing and method of treatment
Embodiments disclosed herein are directed to negative pressure treatment systems and wound dressing systems, apparatuses, and methods that may be used for the treatment of wounds. In particular, some embodiments are directed to improved wound dressings comprising an obscuring layer that may hide fluid contained therein. Some embodiments may further comprise one or more viewing windows disposed therethrough so as to enable monitoring or examination of fluids contained therein. |
| US10076447B2 |
See-through reduced-pressure dressings and systems
A see-through dressing assembly is presented for use with a reduced-pressure system for treating a wound on a patient using reduced pressure that allows visual observation of the wound during treatment. The dressing assembly includes a bolster for providing a directed force when under reduced pressure, a sealing member for covering the bolster and providing a seal over the bolster and a patient's epidermis, and wherein the bolster and sealing member are formed from see-through materials sufficient to allow perception of color from a point external to the system. Other systems, dressings, and methods are presented. |
| US10076442B2 |
Systems and methods for controlling vacuum within phacoemulsification systems
The invention relates to systems and methods for controlling vacuum within phacoemulsification systems. The phacoemulsification system may include a handpiece having a needle coupled to a power Source configured to cause the needle to be ultrasonically vibrated during operation, and an aspiration Source. The system includes a footpedal that defines a first position and a second position, and also includes a computer program product operatively coupled to the handpiece and the foot pedal, having a computer usable medium with a sequence of instructions which causes the processor to control power from the power source and vacuum from the aspiration source applied to the handpiece. The process provides a vacuum at a first level to the handpiece when the footpedal is at the first position; provides power to the handpiece when the footpedal is at the second position; and reduces the vacuum to a second level when the footpedal position transitions. |
| US10076440B2 |
Cerebral protection system
A cerebral protection system generally includes an array of cold packs, an insulating cover, and optionally a set of trays. The cold pack contains two reactive materials separated by a rupturable membrane. When the first reactive material and the second reactive material are mixed, an endothermic reaction occurs. The system can be used to induce hypothermia in selected regions of the brain when used. |
| US10076437B2 |
Portable and readily dismantled human restraint sytem
A portable human restraint system is provided for use by those who practice an alternative sexual lifestyle known as dominance and submission or discipline and bondage. The restraint system includes a bondage frame that can be secured to any door of a room and easily dismantled into a compact size for storage or traveling. The bondage frame has a generally rectangular configuration formed by a top and a bottom cross member that are connected to a pair of laterally spaced vertical posts. The vertical posts are adjustable in height to allow the bondage frame to be extended if needed. A top and a bottom securement brace secure the bondage frame to the door through adjustable reduction sleeves. The reduction sleeves, being adjustable, allow the frame to be positioned further away from the door if needed. A variety of different restraining devices such as ankle and wrist cuffs can be directly or indirectly attached to various locations about the frame with the assistance of various mechanisms such as tie-down ropes and cleats, mountings rings, and spring loaded rings. |
| US10076435B2 |
Stent deployment system with overmolded tip
A deployment system for a self expanding stent includes a catheter assembly with a tip attached to a distal end segment of an elongate tube. The tip includes a proximal portion molecularly joined to a distal portion, which has a lower durometer hardness than the proximal portion. The proximal portion includes an anchor surface in contact with the distal portion, and oriented perpendicular to a central axis of the elongate tube. The elongate tube may be formed from a thermosetting polyimide, and the overmolded tip may be made from two different colored and different hardnesses of polyether block amide material. The tip is overmolded onto an untreated external surface of the elongate tube. |
| US10076433B1 |
Intravascular bifurication zone implants and crimping and deployment methods thereof
A multi stent delivery system for intravascular bifurcation zone delivery and deployment of a multi stent, the bifurcation zone having a main blood vessel, the main blood vessel having a main blood vessel longitudinal axis and at least one side blood vessel inclined/branching out of the main blood vessel, the delivery system comprising: a catheter having a catheter longitudinal axis substantially coaxial with the main blood vessel longitudinal axis, a tube positioned coaxially within the catheter, the catheter having a distal end and a proximal end, and the tube containing: at least one crimped side stent for deployment substantially normal to the catheter longitudinal axis and into the side blood vessel; and at least one crimped main stent for deployment substantially along the catheter longitudinal axis into the main blood vessel; wherein the at least one crimped side stent and at least one crimped main stent are part of a unified/singular configuration within a sheath, located substantially at the distal end. |
| US10076432B2 |
Thumbwheel actuated vascular intervention device delivery system
A vascular intervention device delivery system, such as for implanting a stent, includes a thumbwheel rotatably mounted in a handle. A catheter has a proximal end attached to the handle, and a distal carrier segment for mounting a vascular intervention device thereon. A retractable sheath is movable from a first position covering the distal carrier segment to a second position retracted proximally uncovering the distal carrier segment. A pull extends between the thumbwheel and the retractable sheath. A latch is positioned in the handle and moveable from a locked position at which the latch engages the radially outward thumb surface, and an unlocked position at which the latch is out of contact with the thumbwheel. A pusher, which is partially positioned outside of the handle, is operable to move the latch from the locked position to the unlocked position. The retractable sheath moves responsive to rotation of the thumbwheel. |
| US10076431B2 |
Uncaging stent
A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment. |
| US10076429B2 |
Membrane implant for treatment of cerebral artery aneurysms
The invention relates to a membrane implant (1) for treatment of cerebral artery aneurysms (10), wherein the implant can be implanted endovascularly into vessel segments (2) at the craniocerebral base of pathological (aneurysmatic) dilation (10) and, in combination with a stent, bridges the diseased vessel segment (2) from inside and disconnects it from the blood stream, wherein the membrane implant (1) comprises a biocompatible plastic membrane in the shape of a cylinder or a segment of a cylinder. |
| US10076422B2 |
Spinous process fixation system and methods thereof
An implantable device includes a barrel. The barrel has a first portion and a second portion. The implantable device includes a first plate having multiple projections extending from one side of the first plate, where the first plate is configured to movably couple to the first portion of the barrel. The implantable device includes a second plate having multiple projections extending from one side of the second plate, where the second plate is configured to movably couple to the second portion of the barrel. The barrel is configured to transition from a collapsed form having a first height to an expanded form having a second height, where the second height is greater than the first height. |
| US10076420B2 |
Posterior-stabilized total knee prosthesis
In an orthopedic knee joint prosthesis, an intercondylar fossa of a femoral component cooperates with a spine formed in a tibial component to reproduce the screw home mechanism of a natural knee. When the femoral component and tibial component are positioned to correspond with slight flexion of the knee, the components are mutually rotationally locked against internal or external rotation. At higher degrees of flexion, such as greater than about 10-20 degrees of flexion, internal/external rotation of the tibia is permitted. The tibia is in an externally rotated position when locked, thereby reproducing the screw home mechanism and providing high stability. |
| US10076417B2 |
Joint prosthesis assembly
A joint prosthesis assembly, includes a joint prosthesis body (1) made of a first biocompatible non-resorbable material and an anchoring element (2-5) made of a second biocompatible non-resorbable material. The anchoring element (2-5) is arranged to allow rotation of an end portion of the joint prosthesis body (1) with respect to the anchoring element (2-5) when in situ. |
| US10076415B1 |
Native valve repair devices and procedures
A system for implanting a repair device onto a native valve of a natural heart to repair the native valve of a patient during a non-open-heart procedure. The system includes a base assembly having a plurality of pivoting links, a pair of paddles attached to the base assembly, a pair of gripping members attached to the base assembly, and at least one coaptation or spacer element disposed between the pair of gripping members. Movement of the pivoting links of the base assembly causes the paddles to move between an open position and a closed position. The paddles and the gripping members are configured to attach to valve leaflets of the patient. The coaptation or spacer element is configured to fill at least a portion of a gap between the valve leaflets of the patient. |
| US10076410B2 |
Catheter-guided replacement valves apparatus and methods
The present invention is a replacement mitral valve suitable for catheter-based deployment. The replacement mitral valve has structure and dimensions that are uniquely suited to engage the annulus surrounding the native mitral valve and to restore normal function to a diseased valve. The invention describes the structures and functions of a replacement mitral valve and methods that are adapted for minimally invasive, catheter-based deployment of the valve. |
| US10076408B2 |
Intraocular device with wirelessly coupled auxiliary electronics
Techniques and mechanisms for the wireless transmission of power and sensor information between two components of an implantable ophthalmic device are disclosed herein. An example device includes an accommodating intraocular lens (aIOL) and separate auxiliary electronics, both enclosed in biocompatible materials. The aIOL includes a dynamic optic, control logic, a battery and an antenna. The auxiliary electronics include an antenna, an energy storage cell, and a sensor. The auxiliary electronics may be wirelessly coupled to the aIOL for the wireless transmission of power and sensor information. |
| US10076407B2 |
Adjustable suture button construct
An adjustable construct for fixation of a tendon or ligament graft in a tunnel. The construct comprises a flexible, adjustable loop connected to tissue (for example, graft, ligament or tendon). The adjustable loop may be integrated with an additional tissue supporting device (for example, a wedge or a plug). The tissue is secured within a bone socket/tunnel by adjusting the length of the flexible adjustable loop. |
| US10076403B1 |
Shunt for redistributing atrial blood volume
A shunt for regulating blood pressure between a patient's left atrium and right atrium comprises an anchor comprising a neck region, first and second end regions, and a conduit affixed with the anchor that formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism. |
| US10076402B2 |
Vascular filter with pressure sensor and valve
Systems and devices with an implantable, intravascular filter for preventing emboli from traveling into brain and causing a stroke or transient ischemic attack are disclosed. In particular, an implantable, intravascular device having a filter element, a pressure sensor, and a valve is disclosed. The valve is biased into a closed configuration and changes into an open configuration upon a predetermined pressure drop across the filter. Systems comprising an external device at least one implantable device are also disclosed. |
| US10076400B2 |
Embolic protection device and method
A collapsible, transluminally deliverable embolic protection device (200) for temporarily positioning in the aortic arch is disclosed. The device is connectable to a transluminal delivery unit (130) extending proximally from a connection point (131). The device has a frame with a periphery, and a blood permeable unit within said periphery for preventing embolic particles from passing therethrough into side vessels of said aortic arch to the brain of a patient. Further, the device has at least one tissue apposition sustaining unit, not being a delivery shaft of said device, for application of a force offset to said connection point at said device, such as at said periphery, towards an inner wall of said aortic arch when said device is positioned in said aortic arch, such that tissue apposition of said periphery to an inner wall of said aortic arch is supported by said force. In addition related methods are disclosed. |
| US10076392B2 |
Apparatus and method for mineralising biological material
An apparatus for mineralizing a biological material includes an ultrasonic source, operable to generate an ultrasonic signal, an ultrasonic probe and one or more mineralizing probes, operable to receive a mineralizing agent. The mineralizing agent is transferred from at least one mineralizing probe to the biological material using the ultrasonic signal. Also disclosed are a mineralization agent and a method of mineralizing a biological material that includes the steps of: providing an ultrasound source, providing a mineralizing agent, generating an ultrasonic signal from the ultrasound source, and applying the ultrasonic signal and the mineralizing agent to the biological material separately, sequentially or simultaneously. |
| US10076390B2 |
Light mixture
The invention relates to a light mixing device for a medical or dental-medical lighting device, in particular for a light curing device for the polymerization of dental masses, which device comprises a housing with a light generation device, as well as a light conductor. The light mixing device (2) comprises a bar-shaped light mixing member (8) with preferably at least one transparent material, in particular glass, as well as a holder (7) by means of which the light mixing device (2) is mountable between the light generation device (1) and the light conductor (3) and is held in position by the light conductor (3) as to be separable therefrom. |
| US10076383B2 |
Electrosurgical device having a multiplexer
An electrosurgical system includes an electrosurgical generator configured to provide electrosurgical energy to an electrosurgical device coupled thereto which, in turn, delivers electrosurgical energy to tissue. The electrosurgical device may include a plurality of sensors configured to detect one or more tissue properties and output a detected tissue property signal relating thereto. One or more multiplexers having a plurality of channels are electrically connected to each of the corresponding plurality of sensors. The multiplexer(s) may be configured to receive the detected tissue property signal from each sensor of the plurality of sensors and output at least one output signal along a signal line. The signal line is configured to connect to the electrosurgical generator to control a power output of the electrosurgical generator. A channel select algorithm is configured to automatically select channels from the plurality of channels. |
| US10076382B2 |
Catheter apparatuses having multi-electrode arrays for renal neuromodulation and associated systems and methods
Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present technology, for example, is directed to a treatment device having a multi-electrode array configured to be delivered to a renal blood vessel. The array is selectively transformable between a delivery or low-profile state (e.g., a generally straight shape) and a deployed state (e.g., a radially expanded, generally helical shape). The multi-electrode array is sized and shaped so that the electrodes or energy delivery elements contact an interior wall of the renal blood vessel when the array is in the deployed (e.g., helical) state. The electrodes or energy delivery elements are configured for direct and/or indirect application of thermal and/or electrical energy to heat or otherwise electrically modulate neural fibers that contribute to renal function or of vascular structures that feed or perfuse the neural fibers. |
| US10076378B2 |
Matrix router for surgical ablation
A matrix router with frequency switching is provided having an energy source electrically connected to a plurality of interface ports. A switching device is provided between the energy source and the plurality of switches. One of the plurality of interface ports includes a paired electrode interface port for the connection of a paired electrode device thereto. The paired electrode device has a first pair of opposed electrodes and a second pair of opposed electrodes for clamping on tissue. When the paired electrode device is operably connected to the paired electrode interface port and actuated, the switching device alternates energy such as bipolar RF from the first pair of opposed electrodes to the second pair of opposed electrodes. |
| US10076372B2 |
Bone fixation implants and methods
A plating system is described that uses various configurations of bone fixation implants that are configured to attach to one or more portions of a bone. An exemplary bone fixation implant includes a two-dimensional structure comprising a bone-engaging surface and a tissue-engaging surface. A plurality of openings is defined in the two-dimensional structure, and arranged across a length and a width of the bone fixation implant. At least some of openings are configured to receive an attachment member for securing the bone fixation implant to an underlying bone structure. The tissue-engaging surface is configured to engage an overlying tissue structure for encouraging incorporation of the tissue structure into the bone fixation implant to promote stabilization of the underlying bone structure during healing. In certain embodiments, at least 50% of the area defined by and/or between the length and the width of the two-dimensional structure is an opening. |
| US10076366B2 |
Vertebral lamina supporting device
A vertebral lamina supporting device is provided. The vertebral lamina supporting device includes a first supporting member, a second supporting member and at least one connecting member. The first supporting member includes a first supporting base, in which the first supporting base has a first abutting surface and a first surface opposite to the first abutting surface. The first abutting surface has at least two radially arranged first concave arc portions. The second supporting member is movable relative to the first supporting member. The second supporting member includes a second supporting base, in which the second supporting base has a second abutting surface and a second surface opposite to the second abutting surface. The second abutting surface has at least two radially arranged second concave arc portions. The connecting member is connected between the first supporting member and the second supporting member. |
| US10076362B2 |
Polyaxial bone anchoring device
A polyaxial bone anchoring device is provided including a bone anchoring element (1) comprising a head (3) and a shank (2); a receiving part (4, 4′) for receiving a rod (100) for coupling the rod to the bone anchoring element, the receiving part comprising a first end (4a), an opposite second end (4b) and a central axis (C) extending through the first end and the second end, and a channel (9) for receiving the rod and an accommodation space (11) for receiving the head; a pressure element (6, 6′) arranged in the receiving part and configured to exert pressure onto the head; wherein the pressure element (6) comprises flexible sections (66a, 66b) facing away from the head (3), characterized in that the flexible sections (66a, 66b) comprise a free end portion (69a, 69b) with respect to the central axis (C) that cooperates with an inclined surface portion (15a, 15b) of the receiving part (4) such as to hold the pressure element (6) in a position in which it exerts a pre-load onto the head before the head is locked. |
| US10076358B2 |
Multi-port access device for minimally invasive surgical procedures
An access device for surgical procedures is disclosed which includes a multiport end cap including a plurality of separate access ports for accommodating the introduction of individual surgical instruments into a body cavity or lumen of a patient, and a coupling for operatively connecting the multiport end cap to a tubular body. |
| US10076356B2 |
Subcutaneous needle insertion mechanism
A subcutaneous access device has a skin attachment plate coated with an adhesive layer. The skin attachment plate is moveably linked by a retraction mechanism to a needle support with fixedly positioned needles. In the ready-to-use position the skin attachment plate is spaced away from the needle support and covers the fixedly positioned needles. Subcutaneous insertion of the needles is effected by attachment of the skin attachment plate with the adhesive layer to the skin and releasing the retraction mechanism, thus triggering the pulling of the attached skin with high velocity against the tip of the needles. |
| US10076355B2 |
Circumcision tool
A circumcision tool for securely holding and cutting the prepuce of a penis includes a forceps body and a prepuce clamp. The forceps body includes a first arm and a second arm that are pivotally connected to each other to form a dual-lever body. A first handle is terminally connected to the first arm, while a second handle is terminally connected to the second arm, allowing for manipulation of the first arm and the second arm. The prepuce clamp includes a first hinged clamp and a second hinged clamp; the first hinged clamp being connected to the first arm opposite the first handle and the second hinged clamp being connected to the second arm opposite the second handle. The first hinged clamp and the second hinged clamp are ring shaped members that can be laterally separated to fit around the penis. |
| US10076351B2 |
Medical device and method
A blood vessel dissecting device method involves inserting a dissecting device into a living body, advancing the dissecting device along a vein, and dissecting the vein and tissue bound to the vein from other surrounding tissue. |
| US10076348B2 |
Rotary input for lever actuation
A surgical instrument includes a surgical end effector coupled to an elongate tube and a rod that passes through the elongate tube. A control mechanism coupled to the elongate tube includes an input axle having a first axis of rotation, an idler pulley having a second axis of rotation perpendicular to the first axis, and a lever coupled to the rod and having a third axis of rotation parallel to the second axis. First and second capstans are fixed to the input axle. Cables pass over the idler pulley and are coupled to the lever. Rotating the input axle in a first direction winds a first cable onto the first capstan, rotates the lever, and moves the rod in a second direction. Rotating the input axle opposite the first direction winds a second cable onto the second capstan, rotates the lever, and moves the rod opposite the second direction. |
| US10076347B2 |
Systems, methods and devices for removing obstructions from a blood vessel
Devices and methods for removing an obstruction from a blood vessel are described. The devices are deployed in a collapsed condition and are then expanded within the body. The devices are then manipulated to engage and remove the obstruction. |
| US10076342B2 |
Tissue displacement tools and methods
Apparatus and methods for bone cavity preparation. Formed broaching members may be supported inside a bone by a rotator. The broaching members may be bowed out inside the bone to create a cavity having a shape determined by the broaching members and bone anatomy. |
| US10076341B2 |
Variable angle surgical instrument and method of use
A Variable Angle Surgical Instrument is disclosed and generally comprises: a rail portion including a proximal end, a distal end, and a longitudinal axis extending therebetween; a jaw portion operably coupled to the distal end of the rail portion; wherein the jaw portion rotates to variable angles relative to the longitudinal axis, and the jaw portion operates between a closed position and an open position to clamp down and remove tissue; a locking mechanism operably coupled to the rail portion to lock the jaw portion to an angled position. |
| US10076333B2 |
Surgical apparatus and structure for applying sprayable wound treatment material
A surgical stapling apparatus is provided including a cartridge assembly defining a tissue contacting surface; an anvil assembly defining a tissue contacting surface; and a surgical buttress releasably secured to at least one of the tissue contacting surface of the cartridge assembly and the tissue contacting surface of the anvil assembly by at least one anchor. A loading unit is provided including a surgical buttress releasably secured to an anvil assembly and/or a staple cartridge secured thereto by at least one anchor, and a drive assembly including a knife blade, wherein movement of the drive assembly from a proximal position to a distal position results in the knife blade cutting the at least one anchor and freeing each surgical buttress from the anvil assembly and/or cartridge assembly. |
| US10076332B2 |
Methods for applying surgical staples to internal walls of hollow tissue organs
A method of performing a surgical anastomosis is disclosed. The method includes providing an anastomotic device including a fluid supply channel extending between a handle assembly and a head assembly. The method also includes positioning the head assembly of the anastomotic device adjacent a hollow tissue organ, inserting the head assembly of the anastomotic device into the hollow tissue organ, and discharging an inflation fluid through at least one fluid outlet and into the hollow tissue organ to insufflate at least a portion of the hollow tissue organ. |
| US10076330B2 |
Tissue anchor for securing tissue layers
Tissue anchors comprise a woven filament braid body having an elongated tubular configuration and a foreshortened configuration where proximal and distal ends of the body expand radially into double-walled flange structures while leaving a cylindrical saddle region therebetween. The tissue anchors are deployed through penetrations between adjacent tissue layers, where the flanges engage the outer surfaces of the tissue layers and the saddle region resides within the tissue penetrations. |
| US10076328B2 |
Clip delivery system for heart valve repair and method of use
A device for repair of a heart valve leaflet includes an elongated body having a lumen extending therethrough in a longitudinal direction, a proximal end, and an open distal end. The device further includes a plurality of clips disposed at spaced positions within the lumen, the plurality of clips being configured and arranged to couple to a portion of the heart valve leaflet. At least one clip in the plurality of clips and the heart valve leaflet are capable of translation relative to one another in the longitudinal direction. |
| US10076327B2 |
Flexible actuator mandrel for tissue apposition systems
The invention provides devices, systems and methods for tissue approximation and repair at treatment sites. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site. In addition, many of the devices and systems of the invention are adapted to be reversible and removable from the patient at any point without interference with or trauma to internal tissues. |
| US10076321B2 |
Knee joint capsular disruption and repair
Meniscal extrusion can occur due detachment of the knee capsule from structures of the knee. Disclosed herein are methods to repair the meniscal detachment. Additionally, cadaveric and synthetic models can be used to teach said methods of repair. |
| US10076316B2 |
Needle biopsy device
A device for needle biopsy is provided. The device includes a handle member having proximal and distal portions. A proximal handle member is disposed to the proximal portion of the handle member and a distal handle member is disposed to the distal portion of the handle member. A sheath lumen is disposed within the handle member and extends from the distal portion of the handle member. A needle housing member is partially disposed to the proximal portion of the handle member and a needle is disposed within the sheath lumen. A plurality of protrusions are disposed upon the needle. |
| US10076315B2 |
Soft tissue biopsy or excisional devices and methods
A device for soft tissue biopsy or excision for either handheld or stereotactic table use may comprise a work element configured to selectively open and close at least one articulable beak configured to penetrate tissue, or follow a central lumen of another device or over a wire in a longitudinal direction. Flush and vacuum tissue transport mechanisms may be incorporated. A single tube or an inner sheath and an outer sheath which may be co-axially disposed relative to a work element may be configured to actuate a beak or beaks and provisions for simultaneous beak closing under rotation may be incorporated. |
| US10076312B2 |
Filter assembly for medical image signal and dynamic decimation method using same
The present invention relates to a filter assembly for a medical image signal and a dynamic decimation method using the same. The filter assembly includes a decimation filter that includes an integer number of multiplier accumulators (MACs), changes a cut-off frequency depending on a bandwidth of the medical image signal received through a dynamic impulse response update, and performs a decimation with respect to the received signal according to a decimation ratio, wherein the decimation filter determines a filter coefficient corresponding to an integer interval so as to up-sample the received medical image signal and supplies the filter coefficient to the MACs. |
| US10076311B2 |
Method and apparatus for registering medical images
An apparatus for registering medical images includes a processor configured to acquire, via an ultrasound probe, a first cross-section of a first medical image, the first cross-section comprising a reference point of an object; and a memory configured to store a second medical image. The processor is configured to obtain a second cross-section of the second medical image corresponding to the first cross-section by using the reference point, and register the first and second medical images with each other. |
| US10076309B2 |
Ultrasonic imaging apparatus and control method thereof
Disclosed herein are an ultrasonic imaging apparatus which is capable of accurately and quickly estimating a Point Spread Function (PSF) is usable for restoring ultrasonic images, and a control method which is executable by the ultrasonic imaging apparatus. The ultrasonic imaging apparatus includes: a probe; a receive beamformer configured to beamform an ultrasonic signal and to output the beamformed ultrasonic signal; a Point Spread Function (PSF) database configured to store a PSF which is acquired based on a situational variable, and a phase parameter which is determined based on the situational variable, for the beamformed ultrasonic signal; and an image generator configured to select the PSF and the phase parameter from the PSF database based on the beamformed ultrasonic signal, and to perform deconvolution using an estimated PSF based on the selected PSF and the selected phase parameter in order to generate an image. |
| US10076308B2 |
Ultrasonic diagnosis apparatuses for generating harmonic images and methods of generating ultrasonic images including harmonic images
An ultrasonic diagnosis apparatus may comprise: a probe comprising a transducer configured to transmit a signal to an object and configured to receive an echo signal from the object; a controller configured to control the probe; and/or an image generation unit configured to generate an image of the object based on the echo signal. The controller may be further configured to drive the transducer such that the signal transmitted simultaneously comprises a fundamental frequency and at least one harmonic. A method of generating an ultrasonic image may comprise: transmitting a signal to an object by using a transducer; receiving an echo signal from the object by using the transducer; and/or generating an image of the object based on the echo signal. The transmitting of the signal to the object may comprise driving the transducer such that the signal transmitted simultaneously comprises a fundamental frequency and at least one harmonic. |
| US10076306B2 |
Electric toothbrush with ultrasound sensor
An electric toothbrush includes a handle and a brush head attached to one end of the handle. The brush head includes a bristle unit and an ultrasound sensor. The bristle unit cleans teeth and the ultrasound sensor acquires ultrasound data of the teeth. A portable tooth decay detection device includes a handle and an ultrasound sensor attached to one end of the handle. The ultrasound sensor emits and receives ultrasound signal at a frequency of higher than 20 KHz and acquires ultrasound data of teeth. |
| US10076304B2 |
System for providing scanning medium
A system for providing scanning medium for scanning a volume of tissue comprising: an inner chamber that contains the scanning medium; a transducer mounted to the inner chamber and configured to move along a motion path, with the inner chamber, in scanning the volume of tissue; an outer chamber concentrically aligned about the inner chamber to guide the inner chamber along the motion path; a piston module defining a base surface within the inner chamber, the piston module comprising a medium inlet and a medium outlet for adjusting an amount of the scanning medium within the inner chamber; a detection subsystem coupled to the base surface of the piston module; and an actuator comprising a stationary portion mounted to the piston module and a moving portion coupled to the inner chamber and configured to produce motion of the inner chamber along the motion path. |
| US10076302B2 |
Imaging systems and methods
Versatile, multimode radiographic systems and methods utilize portable energy emitters and radiation-tracking detectors. The x-ray emitter may include a digital camera and, optionally, a thermal imaging camera to provide for fluoroscopic, digital, and infrared thermal imagery of a patient for the purpose of aiding diagnostic, surgical, and non-surgical interventions. The emitter may cooperative with an inventive x-ray capture stage that automatically pivots, orients and aligns itself with the emitter to maximize exposure quality and safety. The combined system uses less power, corrects for any skew or perspective in the emission, allows the subject to remain in place, and allows the surgeon's workflow to continue uninterrupted. |
| US10076300B2 |
Radiographic imaging apparatus and a method of controlling the same
Disclosed herein are a radiographic imaging apparatus and a method of controlling the radiographic imaging apparatus. The radiographic imaging apparatus may include an imager configured to image a subject to obtain image data; a real-time processor configured to communicate with the imager and configured to obtain a real-time processing authority and perform real-time image processing on the image data; and a non-real-time processor configured to communicate with the imager and configured to perform non-real-time image processing on the image data, and in response to a failure occurring in the real-time processor, obtain the real-time processing authority and perform the real-time image processing on the image data. |
| US10076299B2 |
Systems and methods for determining hepatic function from liver scans
Systems and methods for determining an objective metric for analyzing health of a patient's liver are described. In some embodiments, the system may include a scanner that can detect radiation counts responsive to administration of radioactive compound to a patient. Further, the system may include an image detection module that can access image data responsive to the detected radiation counts by the scanner. The image detection module can programmatically identify a first region of interest corresponding to a liver of the patient from the image data. A parameter calculator module can programmatically determine a first attribute associated with the first region of interest and calculate a first parameter indicating health of the liver of the patient based at least in part on the first attribute associated with the first region of interest. |
| US10076296B2 |
User interface for X-ray positioning
The present invention relates to positioning of an X-ray source. In order to provide an improved user interface for facilitating the X-ray imaging positioning, a transportable handheld planning device (10) for visualizing projected X-ray radiation for medical X-ray imaging is provided, that comprises a first structure (12) for representing a central axis (14) of a projected X-ray radiation (16), and a second structure (18) for representing a cross-sectional area (20) of the projected X-ray radiation. The first structure is manually positionable by a user in relation to an object to be examined. The second structure is adjustable by a user such that the size and proportions of the cross-sectional area are adjustable in relation to the object to be examined. Further, a current spatial position of the first structure and a current size and proportions of the cross-sectional area are detectable by a measurement arrangement (22). |
| US10076291B2 |
X-ray CT imaging device
The present invention has an object of providing an X-ray CT imaging device which can direct X-ray to an area of interest appropriately even when, for example, the height of the area of interest with respect to the X-ray detector, which is revolving, varies with respect to the revolution direction, and thus can reduce the amount of unnecessary exposure to the X-ray and can perform X-ray imaging of the area of interest with certainty. In an X-ray CT imaging device for performing X-ray CT imaging of a CT imaging area of a subject, during the X-ray CT imaging when a revolving arm is revolving, the expansion in a length direction of an X-ray cone beam, which is to be restricted by length direction blocking plates, is adapted to the shape of the CT imaging area in accordance with the revolution position of the revolving arm. |
| US10076287B2 |
Method for monitoring physiological status of vehicle driver
A method for monitoring physiological status of a vehicle driver is performed by a monitoring device connected to a physiological sensor and comprises steps of: (a) establishing a personal physiological database comprising steps of: periodically sensing the vehicle driver via the physiological sensor to obtain the physiological signals within an initial duration; obtaining a mean value and a standard deviation based on the physiological signals; and obtaining a tolerance range based on the mean value and the standard deviation, such that the personal physiological database stores the tolerance range; (b) sensing the vehicle driver via the physiological sensor to obtain at least one instant physiological signal after the initial duration; and (c) determining whether the at least one instant physiological signal is out of the tolerance range, such that an alarm is outputted when the at least one instant physiological signal is out of the tolerance range. |
| US10076284B1 |
System, medical item including RFID chip, data collection engine, server and method for capturing medical data
A system includes a plurality of RFID chips affixed to a medical item, a device reader such as a data collection engine device, and a server device. The data collection engine wirelessly transmits power to an RFID chips and receives first medical data from the RFID chip while the RFID chip is activated by the power receiver. The data collection engine generates a first message indicative of the first medical data to be sent to the server device. The server device can determine aspects of the medical item such as position and risk states based upon the first medical data. |
| US10076281B2 |
Device and method for sleep monitoring
A sleep monitoring device (100) is disclosed for measuring a biophysical variable (131) of a living-being (150), comprising at least two pressure sensors (101-103) spatially arranged in a predefined planar geometry. The living-being rests on the supporting layer (199) contacted by the sensors that generate sensor signals in response to pressure caused by the living being via the supporting layer. A processing unit (110) determines the position of the living-being on the supporting layer based on differences between the sensor signals; a magnitude attenuation factor is determined based on the position of the living-being and a position of a sensor; the biophysical variable is determined from a sensor signal generated by that sensor, including a magnitude correction based on the magnitude attenuation factor. The effect of the invention is that only few sensors are needed to measure a biophysical variable accurately, irrespective of the living-being's position on the supporting layer. |
| US10076280B2 |
Bone-conductive arousal induction apparatus
The present invention provides an apparatus and methods to deliver audible acoustic sound to the brain through bone conduction and to terminate snoring and sleep apnea. The apparatus comprises a control module and a device that measures signs of the snoring and the sleep apnea and generates the audible acoustic sound to arouse a subject. The device is reversibly attachable to a part of a head overlying a skull of the subject and uses a composite sensor comprising a reflectance pulse oximeter and a vibration sensor for the measurement and an acoustic speaker for generation of the sound. The device drives the acoustic speaker to produce human-conversational sound and non-human sound. |
| US10076279B2 |
System and method for a compact EEG headset
An EEG headset including an amplifier assembly, a headband assembly formed of a right and a left headband arm and an amplifier platform, a right and left lateral support assembly, at least one hinge assembly connecting at least one of the right or left lateral support assemblies to at least one of the right or left curved arms, and at least one EEG electrode assembly formed of a lead and an electrode. The electrode is in electrical communication with the amplifier assembly via electrical connections within the headset assembly and one of the right and left lateral support assembly. |
| US10076277B2 |
Pain level detection and characterization using capacitive sensors
Systems, methods, sensors, and software for providing enhanced measurement and detection of patient pain response are provided herein. In a first example, a measurement system is provided that includes a capacitive system configured to measure a capacitance signal of tissue of the patient using a capacitive sensor proximate to the tissue of the patient. The measurement system also includes a patient monitor configured to measure an electrical signal representing brain activity of the patient. The measurement system also includes a processing system configured to determine pain metrics based at least on the capacitance signal and the electrical signal, and determine a pain response of the patient based at least on the pain metrics and pain calibration information for the patient. |
| US10076268B1 |
Portable unit for metabolic analysis
The Portable Unit for Metabolic Analysis measures human metabolic function. The compact invention attaches to the face of a subject and it is able to record highly time-resolved measurements of air temperature and pressure, flow rates during inhalation and exhalation, and oxygen and carbon dioxide partial pressure. The device is capable of ‘breath-by-breath’ analysis and ‘within-breath’ analysis at high temporal resolution. |
| US10076263B2 |
System and method for blood brain permeability imaging (BBPI) using dynamic susceptibility contrast magnetic resonance imaging
A system and method for generating dynamic susceptibility contrast information from medical imaging data acquired using a magnetic resonance imaging (MRI) system and from a subject having received a dose of a contrast agent. A plurality of images are acquired of the subject. Using the images, an arrival time correction (ATC) is determined that includes a value for at least one of a time shift variable, a time stretch variable, and an amplitude scale variable. The ATC is applied to a model of dynamic susceptibility contrast that relates a measure of signal change over time with a correction term to dynamic susceptibility contrast information to create a corrected model of dynamic susceptibility contrast including the ATC. At least one contrast agent concentration curve is generated from the plurality of images using the corrected model. |
| US10076258B2 |
Cardiac mapping using latency interpolation
Medical devices and methods for using medical devices are disclosed. An example mapping medical device may include a catheter shaft with a plurality of electrodes. The plurality of electrodes may include a first pair of electrodes, a second pair of electrodes, a third pair of electrodes and a fourth pair of electrodes. The mapping medical device may further include a processor, wherein the processor may be configured to determine a first latency between the first pair of electrodes, determine a second latency between the second pair of electrodes, determine a third latency between the third pair of electrodes, determine a fourth latency between the fourth pair of electrodes, and determine a target signal by interpolating the first latency, the second latency, the third latency and the fourth latency. |
| US10076255B2 |
Apparatus for obtaining cardiovascular information by measuring between two extremities
An apparatus for obtaining information on a cardiovascular system based exclusively on measurements between two limbs and effected with a pair of distal electrodes on each limb. The measurement is made by causing an alternating current to flow between one electrode of each limb and measuring the potential difference between the other two electrodes, one also on each limb. This potential difference has a low frequency component which is an electrocardiogram (ECG) and another component having a frequency of the injected alternating current and from which an impedance plethysmogram (IPG) is extracted. The cardiovascular information is determined by measuring the time interval between any predefined characteristic element of the ECG and IPG. |
| US10076248B2 |
Hybrid catheter system
System and method for obtaining information about a target structure. The system includes an optoelectrical element with an optical fiber having a core, a coating surrounding the core, an optical axis, a proximal end, and a distal end. The optoelectrical element also includes an electrical connector embedded within the coating along the optical axis between the proximal end and the distal end. A transducer is disposed at the distal end and electrically connected to the electrical connector. The transducer is operable to detect a first energy, generated in response to light that has been transmitted from the proximal end to the distal end and outcoupled from the distal end toward the target structure, and to convert the received first energy to an electrical signal to be transmitted along the electrical connector. |
| US10076245B2 |
Specimen information acquisition apparatus and specimen information acquisition method
A specimen information acquisition apparatus includes a signal processor which can selectively operate in first and second modes. In the first mode, when a first group represents a group of devices among receiving devices and a second group represents at least a fraction of a group of devices other than the first group, a photoacoustic image and an ultrasonic image are obtained based on received signals from the first group and the second group, respectively. In the second mode, when a third group represents a group of devices having at least a fraction of a group of devices other than the first group and a fourth group represents at least a fraction of a group of devices other than the third group, a photoacoustic image and an ultrasonic image are obtained based on received signals from the third group and the fourth group, respectively. |
| US10076241B2 |
Vision system responsive to a presence of a wearable ophthalmic element
Described embodiments include a vision system and a method. A vision system includes a receiver circuit configured to receive data indicative of a presence of a wearable ophthalmic element in an optical path incident on a vision correction device. The vision correction device includes an electronically controllable vision parameter and configured to be placed in an eye of a human subject. The vision system includes a controller circuit coupled to the vision correction device and configured to change the electronically controllable vision parameter of the vision correction device at least partially in response to the received data indicative of the presence of the wearable ophthalmic element in the optical path. |
| US10076238B2 |
Systems and methods for visualizing ablated tissue
Systems and methods for visualizing ablated tissue are disclosed. In some embodiments, a system for imaging tissue comprising: a catheter having a distal end and a proximal end; an inflatable balloon disposed about the distal end of the catheter; and an optical housing extending from the distal end of the catheter into the balloon, the optical housing being configured to position inside the balloon a light source for illuminating a tissue outside the balloon and a camera for imaging the illuminated tissue. |
| US10076236B2 |
Bending portion for endoscope and endoscope
There is provided a bending portion for an endoscope and the endoscope which can prevent the piece fall of bending pieces without enlarging the diameter of the bending portion and raising the filling rate of built-in components in the bending portion. In the bending portion, one bending piece of adjacent bending pieces is formed so that a cross-sectional shape is, for example, an elliptic shape whose major axis direction or minor axis direction corresponds to a first direction. The other bending piece of the adjacent bending pieces is formed so that a cross-sectional shape is, for example, a circular shape in which a length in the first direction differs from the first bending piece; and an abutting portion in which their end portions facing each other of the adjacent bending pieces abut on each other in at least two points when the bending portion is bent. |
| US10076235B2 |
Steerable, follow the leader device
A highly articulated robotic probe (HARP) is comprised of a first mechanism and a second mechanism, one or both of which can be steered in desired directions. Each mechanism can alternate between being rigid and limp. In limp mode the mechanism is highly flexible. When one mechanism is limp, the other is rigid. The limp mechanism is then pushed or pulled along the rigid mechanism. The limp mechanism is made rigid, thereby assuming the shape of the rigid mechanism. The rigid mechanism is made limp and the process repeats. These innovations allow the device to drive anywhere in three dimensions. The device can “remember” its previous configurations, and can go anywhere in a body or other structure (e.g. jet engine). When used in medical applications, once the device arrives at a desired location, the inner core mechanism can be removed and another functional device such as a scalpel, clamp or other tool slid through the rigid sleeve to perform. Because of the rules governing abstracts, this abstract should not be used to construe the claims. |
| US10076233B2 |
Device for transmitting a deflection movement, endoscope bending control unit, and endoscope
The invention refers to a deflection movement transmission device comprising a control element (1) arranged at a proximal end of the deflection movement transmission device for effecting a deflection movement, an elongate transmission guiding body (5), and a bendable body (6) to be deflected that is arranged at a distal end of the deflection movement transmission device, wherein the control element (1) comprises an inner channel (16) through which the bendable body (6) to be deflected is guidable. |
| US10076229B2 |
Endoscopic overtube
An over-tube was developed for receiving and guiding endoscopic instruments into a patient's anus, through the colon, and into the peritoneum. The over-tube has a flexible sheath adapted for insertion into the anus through the colon and out the peritoneum of a patient. A stiffened region is used to protect the colonic wall from injury during insertion of medical instruments through the patient's lower gastrointestinal tract. The proximal end of the over-tube is surrounded by two narrow inflatable balloons on either side of the colotomy to keep the device in place with its lumen open into the peritoneum and further prevent leakage of insufflation. The device may comprise two channels, one for duel channel endoscopes and larger medical instruments or single lumen endoscopes, and an additional channel for surgical instruments. A distal valve prevents insufflation leakage, making the device especially useful in NOTES surgeries. |
| US10076226B2 |
Rotating filter for a dishwasher
A dishwasher with a tub at least partially defining a washing chamber, a liquid spraying system, a liquid recirculation system defining a recirculation flow path, and a liquid filtering system. The liquid filtering system includes a rotating filter disposed in the recirculation flow path to filter the liquid. |
| US10076225B2 |
Dishwasher with sprayer
A dishwasher for washing dishes according to an automatic cycle of operation, includes a tub at least partially defining a treating chamber for receiving dishes for cleaning and a spraying system supplying liquid to the treating chamber and having at least one sprayer having a body mounted within the tub for rotation about a rotational axis and defining an interior, a liquid passage provided in the interior, and at least one moveable nozzle carried by the body and having at least one outlet in fluid communication with the liquid passage and a drive mechanism therefor. |
| US10076224B2 |
Dishwasher
A dishwasher for treating dishes includes a tub at least partially defining a treating chamber, a spraying system having a manifold with at least one sprayer for spraying wash liquid into the treating chamber, and a recirculation system for recirculating liquid sprayed in the treating chamber to the spraying system. The sprayer of the manifold has multiple apertures which are configured to emit liquid to different areas of the treating chamber. |
| US10076221B2 |
Cleaning device for bathroom cleaning applications
A device for bathroom cleaning applications includes an extension, a head, and a cleaning utility. The extension defines an extension axis and including a first extension component and a second extension component. The head is fixedly coupled to the extension, and defines a head plane transverse to the extension axis. The head includes at least one resilient member disposed parallel to the head plane, and a receiving surface configured to receive the cleaning utility. Force applied to the extension is transmitted to the cleaning utility via the head to conform the cleaning utility to a remote surface to be cleaned. |
| US10076217B2 |
Upright vacuum cleaner
Several embodiments of an upright surface cleaning apparatus are disclosed. The surface cleaning apparatus has a first cyclonic cleaning stage and comprises a surface cleaning head having a dirty fluid inlet. A fluid flow path extends from the dirty fluid inlet to a clean air outlet of the upright surface cleaning apparatus. A support member is mounted to the surface cleaning head. A portable cleaning unit is removably mounted to the surface cleaning apparatus. |
| US10076210B2 |
Head assembly for brewing apparatus
According to embodiments described in the specification, a head assembly for a brewing apparatus is described. The head assembly includes a lid portion coupled to a fixed base portion and moveable between open and closed positions; a lock coupled to the lid portion and slideable between locked and unlocked positions; a lever with a first end connected to the lock, an axis point connected to the lid portion, and a second end; and a cover movably coupled to the lid portion and abutting the second end of the lever, such that pressure on the cover rotates the lid portion to the closed position, and rotates the lever so as to slide the lock into the locked position. |
| US10076208B2 |
System for the production of beverages
A system for production of beverages includes a beverage dispenser and a pod to be inserted in the beverage dispenser for passage of an extraction liquid of the beverage. The pod includes a filtering body which defines a space that contains a food substance from which the beverage is obtained. The filtering body has on the outside a flange. Further, the system includes a recognition element associated to the filtering body which can be recognized and/or interpreted by a recognition device of the beverage dispenser. The recognition device is electrical and includes an electrical circuit. The recognition element includes a bridge configured to create an electrical contact between two sections of the electrical circuit. |
| US10076207B2 |
Automatic cooking apparatus
An automatic cooking apparatus includes a main housing, a drinking water supply unit, a cooking apparatus and a controller. The drinking water supply unit includes a drinking water tank and a drinking water supplying apparatus including a water delivering unit connected to the drinking water tank. At least one drinking water outlet is provided on the main housing and is connected to the water delivering unit. The cooking apparatus includes a food storage tank and a cooking unit. The cooking unit includes a pot and a heater thermally communicated with the pot. The controller is electrically connected to the drinking water supply unit and the cooking apparatus, and operates the automatic cooking apparatus on at least one of a water supplying mode and a cooking mode. |
| US10076206B2 |
Bayonet fitting pressure cooker provided with a control member
The invention provides a cooking utensil for cooking food under pressure including a vessel, a lid, and a bayonet-fitting locking system, said utensil including a lid subassembly that includes both said lid and a support attached to said lid in such a manner that said lid can pivot, said utensil including a control member for controlling the locking/unlocking, and a transformation device for transforming the movement of the control member into pivoting of the lid relative to the support, said control member being shaped to be capable of being taken hold of manually and being connected mechanically to the support so that said lid subassembly being lifted manually, via the control member, causes the control member to be urged back into its unlocking position. |
| US10076205B2 |
Communion tray having corner cup disposal openings
The present invention solves the problem of possible contamination of unconsumed liquid contained by communion cups that remain in the circular apertures of the cup array of the tray cover. The problem has been solved by moving the empty cup disposal openings from their current central locations in the tray cover to the four corners thereof. The new configuration makes it awkward for a congregant to dispose of his cup by reaching over cups containing unconsumed liquid. Although the improved tray cover is configured to hold 34 cups rather than 36, the loss of capacity of 2 cups is considered to be an acceptable compromise for decreasing the spread of disease causing organisms. |
| US10076204B1 |
Parcel guard with expandable mesh basket receptacle
A parcel guard with expandable mesh basket receptacle is a safeguard mechanism for receiving and keeping packages comprising of a scalable, flexible, collapsible net basket made of wire mesh, metallic chain links, composite material or any combination of material suitable to create a shaped net basket and a means of locking mechanism to deter theft temptation. The flexible net basket of this apparatus allows parcels of various size, shape and weight to be placed inside the net basket and securely locked away as part of a theft prevention mechanism that prevents unauthorized removal of the parcels. |
| US10076203B1 |
System and method for compression garment removal
A system for compression garment removal includes a frame with a first ring-shaped portion having a forward portion, a rearward portion, and an opening therein to permit an individual's foot and lower leg to be placed through the opening, the rearward portion including a hook for engaging a compression garment; a handle coupled to the rearward portion of the first ring-shaped portion; and an elongated pushing rod adapted at one end to engage the forward portion of the first ring-shaped portion. |
| US10076202B1 |
Apparatus to help disabled persons pull up pants and underpants simultaneously after using the toilet
An embodiment of an aid to help disabled persons use the bathroom independently. It includes a cord, attachable to a person's pants at its first end, and a loop which is affixed to the waistband of his or her underpants. The person inserts a clip which is at the second end of the cord through the loop, finally attaching the clip to a place where it may easily be reached, such as his shirt. When using the toilet, he may allow his pants and underpants to drop toward the floor, they being tethered to the cord and attached by the clip to his shirt. His hands may thereby remain free for necessary business. He may easily conclude by grasping the cord and pulling upward, retrieving his pants and underpants simultaneously, without having to bend over. |
| US10076201B2 |
Cup holder
Provided is a cup holder including: a cylindrical body, which has inner sides or both inner sides and outer sides formed of a material for absorbing a beverage or preventing a flow of the beverage and into which an outer circumferential surface of a cup is inserted; and a contamination prevention panel extending from a predetermined portion of an upper side of the body to an opened end of the cup or a height corresponding to a coupling portion of a cup lid mounted on the opened end and absorbing the beverage leaking through a contact portion between the opened end and the coupling portion corresponding to a drinking portion or preventing a flow of the beverage. |
| US10076198B2 |
Portable food or beverage and condiment kit
A food and condiment kit comprising a container with a top, a bottom, and an interior. A tray coupled to the top of the container includes at least one opening to receive a cup with a first end facing the bottom of the container. A ring with an interior edge and a plurality of clasps disposed around the interior edge is coupled to the first end of the cup. A cutting mechanism coupled to the ring protrudes towards the first end of the cup. A lining covers the open end of the cup sealing the contents of the cup from the contents of the container until the cup is rotated around the cutting mechanism to cut the lining and thereby release the contents therein. |
| US10076195B2 |
Display rack
A display rack for displaying articles comprises a base, a vertical post assembly mounted to the base and upstanding therefrom and at least one article holding assembly removably mounted to the vertical post assembly. The article holding assembly comprises a longitudinal mounting arm extending downwardly and away from the vertical post assembly. A pair of longitudinal carrier arms are mounted to the longitudinal mounting arm and extend rearwardly and away from the longitudinal mounting arm and from each other. At least one hanger element is movably mounted to one of the pair of longitudinal carrier arms and extends away from the carrier arm. The hanger element is movable along a longitudinal length of the carrier arm. The hanger element provides for mounting articles thereto to be displayed. |
| US10076194B2 |
Baby carrier
The invention relates to a baby carrier comprising chest straps, a waist belt, and a carrier bag mounted on the chest straps and the waist belt. Said carrier bag comprises a front piece having leg openings, and the front piece forms together with at least a portion of a means a carrier pouch. A lower portion of the front piece forms a first seat support. A second seat support is fixedly arranged at an inside of the lower portion of the front piece between said lower portion and said means. The second seat support is divisible by a partition means so as to enable deactivation said second seat support, and said partition means being arranged in the width direction of the front piece. The second seat support has a seat width which is narrower than the seat width of the first seat support. The front piece is provided at respective leg opening with a side edge which is flexible and/or openable and which permit a narrower leg position of a child when supported by the second seat support. |
| US10076190B2 |
Pillow
A pillow comprising two wings and a bridging section connecting the wings, so that the wings and bridging section form a substantially U-shaped shape. An elastic member and a connecting assembly connect one portion of the elastic member to a first fixing point on a wing or the bridging section and another portion of the elastic member to a second fixing point on a wing or the bridging section, so that the elastic member or the connecting assembly, or both, can pass from one wing to the other, and the elastic member can urge the wings towards one another. The invention provides a more convenient and quicker way of lengthening the elastic member or connecting assembly passing from one wing to the other. |
| US10076185B1 |
Furniture kits and methods of making the same
Example furniture kits and methods of making the same are described. An example method includes coupling a first block of a connector to a rear wall of a disassembled piece of furniture, the first block having a first groove, and coupling a second block of the connector to a side wall of the piece of the furniture, the second block having a second groove. One of the first block or the second block includes an extension and the other of the first block or the second block includes an opening to receive the extension when the first and second blocks are coupled. The example method also includes packaging the rear wall, the side wall and a locking cover into a furniture kit to be used to assemble the piece of furniture. The locking cover is to couple the first and second blocks. |
| US10076182B2 |
Method of providing a visual indication of depletion of a fluid
A method of providing a visual indication of depletion of an oral care fluid. In one aspect, the method provides a visual indication of depletion of an oral care fluid contained within a reservoir of an oral care implement having a delivery member formed of a capillary material. The method includes: a) providing an indicator fluid in the reservoir with the oral care fluid, the oral care fluid being a different color than the indicator fluid and immiscible with respect to the indicator fluid; and b) upon depletion of the oral care fluid from the reservoir, delivering the indicator fluid to a visible portion of the deliver member. |
| US10076181B2 |
Toothbrush having a bristle area design
The present invention concerns a process for producing toothbrushes covered with bristles in an anchor-free manner, in which a tuft of bristles with cylindrical bristles and/or pointed bristles is introduced into a receiving recess of a mold of a bristle-providing machine and, by means of a profiled pin guided in the receiving recess, force is applied to the end facing the pin of the bristles of the tuft of bristles for the alignment thereof, so that the bristles of the tuft of bristles are aligned by means of an end face of the profiled pin and, as a result, form the topography that complements the topography of the end face of the profiled pin, wherein the profiled pin has on the end face that acts on the bristles a discontinuous surface, which forms multiple levels. This achieves a bristle area configuration that has multiple areas of use. A correspondingly produced toothbrush is also described. |
| US10076177B2 |
Compression system for backpack
A compression system for an ergonomic backpack is disclosed. The backpack includes a backpack body having a top side, a bottom side, two lateral sides, a body side, an outer side and a pair of shoulder straps. In the embodiment, each shoulder strap is connected at a junction of the top side and the body side, extended along the corresponding lateral side, threaded through the D-ring with a distal end connected to the backpack body at a junction of the outer side and the lateral side. The invention also comprises an optional back panel and an optional back support device, secured to the body side. The back panel and support device may be filled with padding material such as a gel, foam, rubber, fluid or the like. When the user ties the two straps, the backpack is automatically compressed and moves closer to the user's back The system, operated like a regular two-strap backpack, allows the user to carry heavier loads for a longer period of time with less fatigue. |
| US10076175B2 |
Device for storing, mixing, and applying cosmetic, skincare, food, or pharmaceutical products
A device for storing, mixing and applying skincare, cosmetic, food and pharmaceutical products includes a tubular housing which is used to hold a plurality of dispensing canisters, a plurality of plungers, and a dispensing actuation hub. The plurality of dispensing canisters is used to store various types of skincare, cosmetic, food, and pharmaceutical products. Each of the plurality of plungers is used to dispense products from a corresponding dispensing canister. Each of the plurality of plungers is controlled by the dispensing actuation hub. The device includes a microprocessor housed within the tubular housing and used to control which products are dispensed by the dispensing actuation hub. The device is powered by power supply which is also housed within the tubular housing. A mixing chamber is included within the tubular housing and provides a space for multiple products to be blended. |
| US10076169B2 |
Tote assembly with interchangeable free standing inserts
A tote assembly is provided having a basket and an insert sized to be slideably received within the basket. The insert can be one of a plurality of inserts, each sized to be slideably received within the basket wherein the inserts can have different interior dividers to define compartments for accessories or equipment associated with a particular activity. |
| US10076167B2 |
Luggage system with transport platform
A luggage transport system includes a first piece of luggage, a transport platform movably coupled to the first piece of luggage, and at least one additional piece of luggage supported on the transport platform, wherein the transport platform is adapted to be elevated and lowered relative the first piece of luggage. |
| US10076166B2 |
System for securing luggage
A luggage system includes a first piece of luggage, a second piece of luggage, a first attachment member positioned on the first piece of luggage, and a second attachment member positioned on the second piece of luggage and adapted to couple to the first attachment member to secure the first and second pieces of luggage together, wherein the first and second attachment members are in a movable arrangement when coupled such that the first and second pieces of luggage move relative each other. |
| US10076165B2 |
Bridal set jewelry system with interchangeable heads, shanks and bands
A ring assembly including a shank having a band defining a head mounting area with a through hole defined through the band in the head mounting area. The through hole defines internal threads; and a head including a mount with a post extending therethrough, the post including an area of external threads configured to engage the internal threads to releasably secure the head to the shank. Methods for forming and demonstrating ring assemblies are also disclosed. |
| US10076164B2 |
Jewelry catch
Disclosed are various examples of a jewelry catch. The jewelry catch can include a base eyelet comprising an anchor eye, a pivot eye and a bar that connects the anchor eye to the pivot eye. The jewelry catch can also include a double eyelet that includes a catch eye and a jewelry eye. Further, the jewelry catch can include a male clasp that includes a hook protruding from the male clasp and configured to slide into a channel shaped to receive the hook. Likewise, the jewelry catch can include a female clasp that includes a channel shaped to receive the hook, thereby securing the male clasp to the female clasp through friction between the hook of the male clasp and the channel of female clasp when the jewelry catch is in a closed position. |
| US10076163B2 |
Electric slide fastener system
To provide an electric slide fastener system that can operate appropriately according to a state of an electric slider. An electric slide fastener system includes a slide fastener chain that includes a pair of fastener tapes and element rows including a plurality of elements fixed to the respective fastener tapes, a slider that moves with respect to the slide fastener chain, a power supply that supplies power for the slider to move with respect to the slide fastener chain, and a driving part to which the power is supplied from the power supply and that moves the slider with respect to the slide fastener chain. The elements pass through the slider to open or close the element rows. The slider is powered from outside. |
| US10076160B2 |
Integrated closure device components and methods
A lace tensioning device includes a housing component having an interior region, a first aperture, and a second aperture, and a spool component that is rotatably positionable within the interior region of the housing component. The spool component has a central cylindrical member and a lumen that extends through the central cylindrical portion. The spool component is rotatable within the interior region of the housing component to align one end of the lumen with the first aperture and to align an opposite end of the lumen with the second aperture to enable a lace to be inserted through the first aperture, the lumen, and the second aperture so that opposing ends of the lace are positioned exterior to the housing component. A knot may then be tied in the lace and the lace retracted to couple the lace with the housing component and spool component. |
| US10076156B2 |
Article of footwear with soil-shedding performance
The disclosure relates to articles of footwear and components thereof, including outsoles, which can be used in conditions normally conducive to the accumulation of soil on the outsoles. In particular, the disclosure relates to articles of footwear and components thereof including an outsole with an external hydrogel film having a water uptake rate greater than 20 g/(m2×min0.5). The outsoles can prevent or reduce the accumulation of soil on the footwear during wear on unpaved surfaces such as sporting fields. When the outsoles are wetted with water, the outsoles can become more compliant and/or can rapidly uptake and/or expel water, which can prevent soil from adhering to the outsole and/or can assist in shedding soil present on the outsole. |
| US10076155B2 |
Article of footwear with soil-shedding performance
The disclosure relates to articles of footwear and components thereof, including outsoles, which can be used in conditions normally conducive to the accumulation of soil on the outsoles. In particular, the disclosure relates to articles of footwear and components thereof including an outsole with an external hydrogel film having a water uptake capacity at 24 hours greater than 40% by weight. The outsoles can prevent or reduce the accumulation of soil on the footwear during wear on unpaved surfaces such as sporting fields. When the outsoles are wetted with water, the outsoles can become more compliant and/or can rapidly uptake and/or expel water, which can prevent soil from adhering to the outsole and/or can assist in shedding soil present on the outsole. |
| US10076154B2 |
Article of footwear with soil-shedding performance
The disclosure relates to articles of footwear and components thereof, including outsoles, which can be used in conditions normally conducive to the accumulation of soil on the outsoles. In particular, the disclosure relates to articles of footwear and components thereof including an outsole with an external hydrogel film that compositionally includes crystalline regions and amorphous hydrophilic regions, where the amorphous regions are covalently bonded to the crystalline regions with carbamate linkages and/or polyamide linkages. The amorphous regions are present in the hydrogel at a ratio of at least 20:1, by weight, relative to the crystalline regions. The outsoles can prevent or reduce the accumulation of soil on the footwear during wear on unpaved surfaces such as sporting fields. When the outsoles are wetted with water, the outsoles can become more compliant and/or can rapidly uptake and/or expel water, which can prevent soil from adhering to the outsole and/or can assist in shedding soil present on the outsole. |
| US10076150B1 |
Hat with integrated sweat-guiding band
An integrated sweat-guiding band and hat comprises a sweat-guiding band having a sweat-guiding portion and an adjustment portion wherein the sweat-guiding band further comprises a base wall and an upwardly extending containment wall defining a channel for conducting sweat away from a user's eyes, the sweat-guiding portion having a plurality of upwardly extending tabs. Adjustment straps are permanently attached to the sweat-guiding band, the adjustment straps including means for adjustably securing the sweat-guiding band to a user's head. A front panel of the hat is configured to couple front the front panel to the upwardly extending tabs to attach the cap/visor to the sweat-guiding band. The tabs are configured to be connected to the front panel in a manner that holds the front panel away from a user's forehead. |
| US10076149B2 |
Adjustable facial protection systems
Devices, systems, and methods, etc., that provide, in certain aspects, a two-point, adjustable, partially pliable, and releasable tensioning suspension that supports an anti-blunt-force frame connected to a protective helmet. The protective devices herein can be, for example, “sport-level” and “military/law enforcement-level.” The anti-blunt-force frame is positioned and balanced on the wearer's face by an impact absorbing face padding system, including a chin strap, cup or pad comprised of an impact protection material. Thus, in one aspect, the present devices, systems, methods, etc., include an adjustable facial protection system for a human comprising a crescent-shaped face protection element configured to withstand blunt force impact and a ballistic material element to prevent the penetration of ballistic and fragmentation projectiles at various force levels to meet different ballistic hazards. The systems can also include a protective helmet. |
| US10076146B2 |
Belt with five deadly blades for self defense
A belt with five different shapes of blades, this belt can be used as a weapon in self-defense. The belt has an extended reach of about 4-6 feet depending on the user's belt size and arm length to strike an adversary, the belt includes a buckle that works as a sheath to conceal any one of the five deadly blades that have been designed to be used as a weapon to strike, cut or spear ones attacker, the belt can be worn with a suit or casual dress, the belt is made of leather, rubber and or elastic and stainless steel. |
| US10076132B2 |
Methods of incorporating micropellets of fine particle nutrients into snack food products
Nutritious granular materials of fine particle sizes agglomerated within versatile micropellets are useful for inserting significant amounts of nutritious properties into snack foods. Expandable micropellet-containing formulations provide for introduction of fine particle ingredients such as proteins, minerals and other components or desirable nutrients into food processing lines not typically amenable to the fine particle sizes. Micropellet-containing formulations may consist entirely of micropellets, or may contain an expandable starch such as, for example, corn meal, sheeted doughs, and expanded collet products onto which the micropellets may be basted. |
| US10076131B2 |
Metabolic imprinting
The present invention generally relates to the field of nutrition. In particular the present invention relates to infant nutrition in the post natal period and in early life, more particular during the age period of 6-36 months or during a part thereof. One embodiment of the present invention is a kit of diet compositions for children during the age period of 6-36 months or during a part thereof, wherein the macronutrient content of the compositions is gradually changing in the form of a straight line from a composition that comprises about 40-50% energy from fat and about 40-49% energy from carbohydrates for children at the age of 6 months to a composition that comprises about 30-35% energy from fat and about 50-55% energy from carbohydrates for children at the age of 36 months, and its use to prevent obesity later in life. |
| US10076124B2 |
Rapid-agitation mixer for food products
The techniques described herein provide, in one embodiment, a rapid-agitation mixer for food products that comprises a product holder configured to hold a sealed product cup containing a food product to be mixed, and a drive shaft along an agitation axis, the drive shaft configured to secure the product holder and product cup in place. The illustrative mixer also comprises a drive motor configured to reciprocate the drive shaft in opposing directions, where the product holder correspondingly reciprocates the product cup to churn the food product within the product cup. |
| US10076121B2 |
Method of baking
Disclosed is the making of baked products, more particularly making of baked products using polypeptides having lipolytic activity and at least one emulsifier. The invention also relates to compositions comprising polypeptides having lipolytic activity and at least one emulsifier. |
| US10076120B2 |
Seed-origin endophyte populations, compositions, and methods of use
This application relates to methods and materials for providing a benefit to a seed or seedling of an agricultural plant (e.g., an agricultural grass plant), or the agricultural plant derived from the seed or seedling. For example, this application provides purified bacterial populations that include novel seed-origin bacterial endophytes, and synthetic combinations of seeds and/or seedlings (e.g., cereal seeds and/or seedlings) with heterologous seed-derived bacterial endophytes. |
| US10076118B2 |
Methods of making antimicrobial poly(methyl methacrylate) /silver nanocomposites and inhibiting bacterial growth with poly(methyl methacrylate) /silver nanocomposites
A method of making an antimicrobial poly(methyl methacrylate) (PMMA)/silver nanocomposite comprising PMMA and silver nanoparticles. The method includes reacting at least one silver salt with a methyl methacrylate (MMA) monomer in at least one organic solvent free of water and in the presence of at least one organic free radical initiator to polymerize the MMA monomer to form the PMMA by free radical polymerization while reducing in-situ the silver salt to form the silver nanoparticles, wherein the silver nanoparticles have an average particle size of 35-60 nm, and wherein the PMMA forms a matrix that encloses the silver nanoparticles. |
| US10076110B2 |
Dog repellent system for cyclists
A dog repellent system for including in the original construction of, or to be added to an existing vehicle that lacks a protective barrier for operators and passengers, such as bicycles, motorcycles, and the like. |
| US10076108B2 |
Insect trap apparatuses and methods of using the same
The present invention relates to trap apparatuses for trapping insects therein. Specifically, the trap apparatuses comprise a conically-shaped passage leading to a holding reservoir for holding the insects therein. Flanges may be disposed at the bottom of the conically-shaped passage portion for securing the same over or otherwise in proximity to an insect nest. The insect trap apparatuses of the present invention are particularly useful for trapping yellow jackets and other like insects that create nests in the ground, in cracks in walls or other vertical structures, or other similar areas. |
| US10076106B2 |
Fishing line of core-sheath structure comprising short fiber
A yarn which contains a composite yarn composed of a core part containing a short fiber and a sheath part containing a synthetic fiber filament yarn, the core part and the sheath part being integrated via fluff of the short fiber getting between or entangled with the long fibers, the specific gravity of the yarn being adjustable in the range of 1.0 or more, a fishing line containing the yarn, and a method for producing the fishing line. The present invention provides an ideal fishing line which has a strong core-sheath structure, does not allow separation or detachment of the core part and the sheath part, is easy to handle, and also is excellent in strength, weatherability, and water resistance. |
| US10076105B2 |
Darting fishing lure
A fishing lure having planar sides is provided. The fishing lure having substantially planar sides such that the fishing lure can be made to dart and stop by a user while maintaining the lure's position in the water column. The fishing lure may also include chambers for weights and attractants or any combination thereof. The fishing lure may also include a user-flexible tail that allows a user to control motion within the fishing column. |
| US10076099B2 |
Predation detection animal tracking tag
A magnetic tracking tag for animals may detect the occurrence of a predation event. The tag may include a pH sensitive material that degrades in the environment of a predator's gut. The degradation of the pH sensitive material causes a change in a detectable magnetic field of the tag, which allows the tag to detect the predation event and adjust its operation accordingly. |
| US10076097B1 |
Soybean cultivar CL1463417
The present invention is in the field of soybean variety CL1463417 breeding and development. The present invention particularly relates to the soybean variety CL1463417 and its seed, cells, germplasm, plant parts, and progeny, and methods of using CL1463417 in a breeding program. |
| US10076096B1 |
Hybrid corn variety 17137678
The invention provides seed and plants of the hybrid corn variety designated 17137678. The invention thus relates to the plants, seeds and tissue cultures of the variety 17137678, and to methods for producing a corn plant produced by crossing a corn plant of variety 17137678 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety 17137678. |
| US10076090B2 |
Growing systems and methods
Growing systems may include a number of modular growing chambers adapted to be configured in a stacked arrangement with each growing chamber surrounding a corresponding portion of the plant. The grow chambers may be selectively added or removed during plant growth, such that different sections of the growing plant may be influenced differently using aeroponic, hydroponic or other growing techniques. The grow chamber stack may be portable and provided with integrated or independent lifting devices to assist an operator in adding or removing chambers from the stack. Three growing processes may be facilitated using such systems. These include a process for producing assorted product from a single plant for simultaneous harvest, a process for producing an extended harvest of a desired size product from a single plant, and a process for extending the productive life of a plant and provide for multiple, continued, and perpetual harvest. |
| US10076088B2 |
Agricultural crop and field sprayer and method for controlling an agricultural crop and field sprayer
An agricultural sprayer (1) with a pump (20), a plurality of nozzles, a valve arrangement (28) associated with the nozzles and a feed conduit (25). The valve arrangement (28) selectively connects the feed conduit (25) to a bypass conduit (26) or to the nozzles. A return conduit (32) branches off from the feed conduit (25). A regulation valve (30) applies a variable degree of throttling to the fluid flowing through the return conduit. A pressure sensor (41) provides a signal for fluid delivered to the valve arrangement. A flow sensor (42) provides a signal representing the flow in the feed conduit (25). A controller (50) is in receipt of the sensor signals, receives instructions from an operator and controls the regulation valve (30) using the instructions from the operator and available measured signals using feedback control loops combined with a feed forward signal. |
| US10076087B2 |
Aerial plant planter
An aerial plant planter includes a fixing portion; and a retaining portion upwardly extended from the fixing portion, wherein the retaining portion comprises at least three retaining members, wherein the retaining members are universally and spacedly arranged around an axis to from a retaining cavity having a retaining opening, wherein a diameter of the retaining cavity is gradually increased from the retaining opening. |
| US10076083B2 |
Plant cultivation method
To provide a technique whereby, in cultivating a crop, factors relating to differentiation into flower buds and leaf buds, sprouting, flowering and fruiting, growth of young shoots, etc., are regulated. For example, the invention addresses the problem of regulating the growth of a crop so that leaf buds sprout in tandem and with the sprouting of flower buds and flowering and fruiting are repeated under fresh foliage. [Solution] A plant cultivation method which comprises environmentally stimulating a plant to regulate differentiation into flower buds and/or differentiation into leaf buds. In a typical embodiment, the plant is help in an environment at a temperature of 16-40° C. at a photoperiod of 8-13 hours immediately after harvesting fruits. As another environmental stimulus, the plant is held in, for example, an environment at a temperature of 3-7° C. As still another environmental stimulus, the plant as held in, for example, an environment at a temperature of 16-23° C. at a photoperiod of 8-11 hours. |
| US10076079B2 |
Agricultural harvester clean grain elevator
An agricultural harvester is described, the harvester comprising a processor for receiving a flow of harvested crop and processing the harvested crop, an on-board tank for storing the processed crop, and a loading arrangement for transporting the flow of processed crop from the feeder to the on-board tank. The loading arrangement comprises an auger, the auger comprising a lower section with an inlet for receiving the flow of processed crop and an upper section with an outlet. The auger further comprises a tubular housing and an auger fighting mounted inside the tubular housing for, during use, transporting the flow of processed crop from the lower section to the upper section and outputting the processed crop via the outlet of the upper section. A clearance between the housing and the auger fighting is larger in the lower section of the auger compared to the upper section. |
| US10076078B2 |
Lateral shake mechanism for agricultural harvester cleaner
An agricultural harvester includes a grain processing section having a crop material handling assembly. The crop material handling assembly is driven in fore and aft oscillation by a device while permitting side to side movement. A pivotal link mechanism structurally connected to the crop material handling assembly midway between its side members and to the agricultural harvester chassis drives linear side to side movement of the crop material handling assembly while permitting fore and aft movement thereof. |
| US10076073B2 |
Agricultural metering system having multiple sets of meter rollers
An agricultural metering system includes multiple independently controllable sets of meter rollers. Each set of meter rollers includes at least one meter roller, each set of meter rollers is configured to rotate about a respective rotational axis, the rotational axes are generally perpendicular to a common plane, and the rotational axes are offset relative to one another in the common plane. The agricultural metering system also includes multiple meter boxes configured to receive agricultural product from a storage tank. Each set of meter rollers is disposed within a respective meter box, and each set of meter rollers is configured to meter the agricultural product from the storage tank. In addition, the agricultural metering system includes multiple distribution lines. Each distribution line is disposed downstream from a respective set of meter rollers and configured to receive the agricultural product output from the respective set of meter rollers. |
| US10076072B2 |
Tillage implement with intra-wing gang offset
A tillage implement has a main frame, a hinged wing and a plurality of gangs each having tools along its length. The plurality of gangs includes a main frame gang mounted to the main frame and inner and outer wing gangs mounted to the wing. The inner and outer wing gangs have inner ends that are forward or rearward with respect to the direction of travel of outer ends, and the lengths of the inner and outer wing gangs are offset from each other in the direction of travel. |