最新美国发明专利第2018-09-11期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US10072405B2	Drain cleaning apparatus A drain cleaning apparatus, includes a handle and a clog-catching member detachably connected the handle. Airplane-like wings project radially from the clog-catching member. The wings provide an angled projection that catches and holds a clump of debris in a drain pipe for unclogging the drain. Clog-catching members or smooth extension members can be connected end to end for different lengths. Different end tools can be removably connected to a clog-catching member or to a smooth extension member to provide multifunctionality. A drain cleaning harpoon that is an integral unit or one that can be assembled and disassembled is also provided. The harpoon can be fitted on one end with a plurality of J hooks, fish hooks, arrowheads or retractable barbs for catching and holding a mass of debris in a drain pipe.
US10072403B2	Human body detection sensor and automatic faucet A human body sensor has a light emitting portion to emit light to an object, a light reception portion to receive the light reflected from the object, a light reception amount determiner, a distance measurement determiner, a moving object determiner, and a detection determiner. When an amount of the reflected light is a threshold or more under the detection state, the detection determiner determines to switch the determination from the detection state to the non-detection state under a condition that the distance measurement determiner determines that the detection target does not exist, and when an amount of the reflected light is less than the predetermined threshold under the detection state, the detection determiner determines to switch the determination from the detection state to the non-detection state under a condition that the moving object determiner determines that the object does not exist.
US10072402B2	Sprayhead retraction assembly A method of installing a sprayhead retraction assembly includes providing a portion of a hose in a groove defined by a first pulley, and coupling a first end of a constant-force spring to a first surface. The method further includes coupling a second end of the constant-force spring to a second pulley, and coiling the constant-force spring around the second pulley, wherein the second pulley is coupled to and offset from the first pulley.
US10072395B2	Shovel and control method thereof A shovel includes a lower running body and an upper turning body that is turnably provided on the lower running body. An engine is mounted on the upper turning body. A hydraulic pump is driven by the engine to discharge an operating oil. A hydraulic actuator is mounted on the upper turning body. A control device controls operations of the shovel. An entering object detection device detects a position of an entering object in a monitoring area of said shovel and outputs a detection signal indicating the detection position of said entering object. The control device supplies, after a determination of an entry of the entering object into the monitoring area, the operating oil from the hydraulic pump to the hydraulic actuator.
US10072394B1	Control system and operating method in machine having rotatable operator station A control system for a machine with a rotatable operator station includes sensors to produce data indicative of suitability and unsuitability of the machine for initiating and completing adjustment, respectively, between a first control configuration where the operator station is at a first orientation and a second control configuration where the operator station is at a second orientation. A control device in the control system transitions the control system between a locking state for inhibiting rotation of the operator station and an unlocking state for permitting rotation, based on the suitability data and the unsuitability data.
US10072393B2	Sliding beam for supporting a work machine The present invention relates to a telescopic sliding beam for supporting a work machine comprising a sliding beam box and an internal sliding beam that is outwardly telescopically supported in the sliding beam box. The sliding beam box and the internal sliding beam have an opening in the peripheral region, with the openings overlapping one another in an outwardly telescoped state, and with a bolt being able to be introduced into the overlapping openings. The sliding beam box has an abutment at its inner side and the internal sliding beam has an abutment at its outer side, with the abutment of the sliding beam box and the abutment of the internal sliding beam contacting one another in an outwardly telescoped state such that a further pulling of the internal sliding beam out of the sliding beam box is suppressed. The invention furthermore comprises a work machine comprising this telescopic sliding beam.
US10072392B2	Boom foot design with protruding flanges A boom and boom foot section for connection to a machine, where the boom includes a center section and a box section extending between the foot and center sections. The box section includes first and second side walls. The foot section includes a machine connection for connecting the boom to the machine, and first and second protruding flanges. The first flange couples to the first side wall, and the second flange couples to the second side wall. The foot section can include a bulkhead. The machine connection, bulkhead, and flanges can be formed by a single piece of material. The flanges can be coupled to the side walls by weld joints that do not have weld roots. The flanges can extend beyond the bulkhead to allow internal welds in the weld joint. The flanges and side walls can have double-beveled edges for the weld joints formed by fused groove welds.
US10072389B2	Coupler for soil nail and method of emplacing same A coupler interconnects adjacent sections of soil nail members to extend a length for a soil nail to be installed. The coupler includes a plurality of projections extending from the exterior surface of the coupler. The projections serve multiple purposes. One purpose is to center the soil nail within a drilled hole. Another purpose is to provide mixing for selected amounts of drilled material to remain within the hole, and/or evacuation of drilled material to be removed from the hole. Another purpose is to create a drilled hole with varying diameters in response to different geological layers encountered during drilling. The coupler with projections therefore serves as a secondary drill bit implement. The size of the projections can be altered to selectively enlarge a desired portion of a drilled hole. The invention further includes a soil nail assembly and a method for installing a soil nail assembly including couplers with projections.
US10072384B2	Concrete plate and sleeve dowel device with alignment surfaces A concrete dowel device including a sleeve and plate in which the sleeve includes break-away alignment tabs at the opening of the sleeve to ensure proper alignment of the plate within the sleeve during field installation. The tabs are positioned at the sleeve opening, rather than along the length of the socket, to avoid misalignment of the plate in the sleeve, simplify use and reduce manufacturing costs of the product. The sleeve and plate may include additional alignment surfaces on the plate, at the rear corners, or along the rear side of the plate and sleeve. To facilitate manufacturing, the break-away alignment tabs may be formed as molded components rotated and snapped into position. Alternatively, the break-away alignment tabs may be formed as part of an insert plate manufactured apart from and attached to the flange of the sleeve.
US10072377B2	Prepreg and fiber-reinforced composite material A fiber reinforced composite material having high interlaminar toughness and compressive strength under wet heat conditions, as well as an epoxy resin composition for production thereof and a prepreg producible from the epoxy resin composition is described. The prepreg includes at least constituents [A], [B], and [C] as specified below and reinforcement fiber, wherein 90% or more of constituent [C] exists in the depth range accounting for 20% of the prepreg thickness from the prepreg surface: [A] epoxy resin; [B] epoxy resin curing agent; and [C] polymer particles insoluble in epoxy resin.
US10072371B2	Washing machine Disclosed herein is a washing machine including a time setting unit configured to set an operation time, and a controller configured to control the laundry treatment operation so as to be terminated before expiration of the operating time by adjusting at least one of a level of water supplied to a washing tub to execute at least one of the wash and the rinse, a number of times of executing the rinse and an execution time of the spin-dry, according to the operation time set through the time setting unit.
US10072369B2	Laundry treating appliance for limiting water usage in small loads A laundry treating appliance for treating laundry according to a cycle of operation includes a rotatable basket defining a laundry treating space and having a bottom wall and a side wall. The bottom wall of the rotatable basket includes at least one drain hole. A centrifugally actuated valve comprising a weighted ball is positioned to selectively open and close the at least one drain hole as the basket rotates.
US10072364B2	Rapid drying woven terry fabric and related articles A terry fabric includes a ground component comprising a plurality of warp yarns and a plurality of weft yarns interwoven with the plurality of warp yarns. At least one of the plurality of warp yarns and the plurality of weft yarns include 5 twisted or plied yarns. The woven terry fabric includes a pile component that projects from the ground component in a direction away from the ground component. The pile component includes a plurality of piles that include absorbent pile yarns interwoven with the plurality warp yarns and the plurality of weft yarns.
US10072358B2	Process for recycling composite materials The present patent of invention describes a recycling process to recover fibrous reinforcing material of composite materials, particularly carbon fiber, primary reactor compound (101), for the controlled pyrolysis and oxidation of the composite material matrix (resin) at low temperature (400° C. to 500° C.) and a system for treating waste gases produced by thermal decomposition of composite material matrixes which employs a secondary reactor (201), containing within the same a thermal plasma arc (211). The main characteristic of the process, within the scope of the carbon fiber recycling, is the possibility of maintaining the fabric web, obtaining fabrics made of pure carbon fiber, without a significant amount of residues and preserving their structural characteristics. The thermal plasma allows managing high temperatures (2,000° C. to 15,000° C.) in a controlled atmosphere, which allows the dissociation of long chains of molecules into ions that are recombined to produce combustible gases and other acid or alkaline gases that are easily neutralized and retained in gas cleaning systems.
US10072349B2	Etch solutions having bis(perfluoroalkylsulfonyl)imides, and use thereof to form anode foils with increased capacitance Anode foil, preferably aluminum anode foil, is etched using a process of treating the foil in an electrolyte bath composition comprising a sulfate, a halide, an oxidizing agent, and a surface active agent. The anode foil is etched in the electrolyte bath composition by passing a charge through the bath. The etched anode foil is suitable for use in an electrolytic capacitor.
US10072347B2	Systems and methods for tin antimony plating Systems and methods for tin antimony plating are provided. One plating method includes doping a tin (Sn) plating solution with antimony (Sb). One method also includes electroplating a component using the antimony-doped tin plating. The antimony-doped tin plating formed by one method includes between about 1% and about 3% antimony.
US10072346B2	Method for producing metal and method for producing refractory metal Provided is a method for producing metal by molten salt electrolysis, by which the metal can be efficiently produced.A method for producing metal by using an apparatus for molten salt electrolysis having an electrolytic cell and an electrode pair, wherein the molten salt electrolysis in the electrolytic cell and heating of the molten salt by a Joule heat generation between a pair of electrodes for electrolysis are simultaneously performed; and wherein the apparatus for molten salt electrolysis has at least two sets of electrode pair, and at least one set of the electrode pairs is electrically opened.
US10072344B2	Device and apparatus for carrying out chemical dissociation reactions at elevated temperatures A reactor is provided which comprises: a plurality of reaction units located within a reaction zone, each of the reaction units being adapted to enable carrying out a chemical reaction of one or more raw gases (e.g. at least one of CO2 and H20); ingress means to allow introduction of the one or more raw gases into the reaction zone and to allow distributing the incoming gas to the plurality of reaction units; egress means to allow exit of reaction products from the reaction zone; and a heating system. The reaction units extend essentially along a longitudinal axis of the reaction zone and are arranged in a spaced-apart relationship along a lateral axis of the reaction zone. The heating system comprises a plurality of heating sources extending along the reaction zone, thereby providing at least a part of the energy to carry out the reaction process within the reaction units.
US10072343B2	Air quality by eliminating greenhouse gas emissions through a process of conversion of flue gases into liquid or semi-solid chemicals Apparatus for removing Greenhouse Gases from combustion of fossil and non-fossil fuels, including hydrocarbons and biomass fuels, is disclosed. The apparatus includes: a vessel containing a liquid medium; a circulation system with a pump; a plurality of positively charged metal plates, each with a plurality of apertures; a negatively charged discharge pipe connected to the circulation pipe; a refrigeration system on the outside of the vessel; and a power source. The apparatus uses the process of electrolysis and electrostatic induction to form covalent bonding among various constituents of Greenhouse Gases and thereby converts and condenses all or most of Greenhouse Gases in the emission. The apparatus has a working prototype. The apparatus can be used in converting and condensing all or some Greenhouse Gases from emissions of power plants and all types of industrial plants which generate Greenhouse Gases as emissions, as well as from various sources of vehicular emissions.
US10072340B2	Method of cleaning of steel sheet surface and use of a detergent composition thereof The present invention provides a method of manufacturing a steel sheet using a detergent for a steel sheet having a good washing property for the oil stain even at a low temperature. The method of manufacturing of the present invention is a method of manufacturing a steel sheet, comprising: a washing step of soaking a steel sheet to which a stain is stuck in a detergent for a steel sheet for washing and a rinsing step of rinsing with water the steel sheet that is soaked and washed after the washing step, wherein the detergent for a steel sheet comprises: an alkali agent, one or more organic acid(s) or salt(s) selected from lactic acid, oxalic acid, citric acid, and salts of these, a nonionic surfactant represented by the general formula (1), one or more chelating agent(s) selected from gluconic acid, ethylenediaminetetraacetic acid, and salts of these, and water.
US10072339B2	Compositions for use in corrosion protection The invention relates to compositions, methods and preparation of such compositions to protect metals from corrosion, especially acid corrosion. The compositions of this invention may be added to acids to protect metals from their corrosive influence, particularly at elevated temperatures. These compositions are of particular utility in the oil and gas (petroleum) industry. Also disclosed are “corrosion inhibition intensifiers” to enhance the corrosion inhibition properties of other corrosion inhibitors. Formulations which control ferric ions in acidic solutions are also disclosed. These may be combined with inhibited acids and some compositions provide both corrosion inhibition and ferric ion control.
US10072338B2	Surface conditioning composition, method for producing the same, and surface conditioning method The present invention provides a surface conditioning composition having a surface conditioning function that is even more superior as compared with conventional surface conditioning compositions.A surface conditioning composition is provided for use in surface conditioning of a metal prior to being subjected to a phosphate-based chemical conversion treatment, in which the surface conditioning composition has a pH of 3 to 12, and includes nearly spherical zinc phosphate particles having an average particle diameter from 0.05 μm to 3 μm, and in which the zinc phosphate particles are produced by mixing at least one kind of zinc compound particles selected from the group consisting of zinc oxide, zinc hydroxide, and basic zinc carbonate with phosphoric acid and/or condensed phosphoric acid to allow for their reaction in an acidic aqueous solution having a pH lower than 7, and dispersing and stabilizing by a dispersion means.
US10072335B2	Method of coating of object A method of coating a metallic object with a substantially invisible protective coating, wherein the coating comprises a first layer, a second layer, and a third layer, each layer comprising a metal oxide or a nitride. The method comprises placing the object in an atomic layer deposition (ALD) reactor; depositing a first layer comprising a metal oxide or a nitride on a surface of the object by ALD; depositing a second layer comprising a metal oxide or a nitride on the first layer by ALD; and depositing a third layer comprising a metal oxide or a nitride on the second layer by ALD, thereby forming the protective coating on the object.
US10072331B2	Method for forming silicon film and method for manufacturing power storage device A formation method of a silicon film which contributes to improvements in cycle characteristics and an increase in charge/discharge capacity and can be used as an active material layer is provided. In addition, a manufacturing method of a power storage device including the silicon film is provided. The formation method is as follows. A crystalline silicon film is formed over a conductive layer by an LPCVD method. The supply of a source gas is stopped and heat treatment is performed on the silicon film while the source gas is exhausted. The silicon film is grown to have whisker-like portions by an LPCVD method while the source gas is supplied into the reaction space. A power storage device is manufactured using, as an active material layer included in a negative electrode, the silicon film grown to have whisker-like portions.
US10072330B2	Shield mask mounting fitting for a sputtering apparatus A shield mask mounting fitting includes a shied mask to be mounted on a chamber wall of a sputtering apparatus, the shield mask including a fixing hole, a fixing bolt connecting the shield mask to the chamber wall through the fixing hole, a cap hook surrounding a top of the fixing bolt, a bushing extending between a surface of the shield mask and the cap hook, and a shield cap engaged with the cap hook and covering the top of the fixing bolt, the shield cap extending beyond the cap hook to omnidirectionally cover a periphery of the fixing hole, wherein one of the cap hook and the shield cap has an asymmetric structure with respect to an axis extending through a center of the fixing bolt.
US10072328B2	High-precision shadow-mask-deposition system and method therefor A direct-deposition system capable of forming a high-resolution pattern of material on a substrate is disclosed. Vaporized atoms from an evaporation source pass through an aperture pattern of a shadow mask to deposit on the substrate in the desired pattern. Prior to reaching the shadow mask, the vaporized atoms pass through a collimator that operates as a spatial filter that blocks any atoms not travelling along directions that are nearly normal to the substrate surface. As a result, the vaporized atoms that pass through the shadow mask exhibit little or no lateral spread (i.e., feathering) after passing through its apertures and the material deposits on the substrate in a pattern that has very high fidelity with the aperture pattern of the shadow mask. The present invention, therefore, mitigates the need for relatively large space between regions of deposited material normally required in the prior art, thereby enabling high-resolution patterning.
US10072324B2	Cold-rolled steel sheet and method for manufacturing same, and hot-stamp formed body A cold-rolled steel sheet has a predetermined chemical composition, in which a structure before and after a hot-stamping includes ferrite: 30 area % to 90 area %, martensite: 0 area % or more and less than 20 area %, pearlite: 0 area % to 10 area %, retained austenite: 5 volume % to 20 volume %, and rest structure: bainite, a hardness of the retained austenite measured with a nano indenter before and after the hot-stamping satisfies relations of H2/H1<1.1 and σHM<20, and a relation of TS×El≥20000 MPa·% is satisfied.
US10072323B2	Hot rolled ferritic stainless steel sheet, method for producing same, and method for producing ferritic stainless steel sheet This hot-rolled ferritic stainless steel sheet has a steel composition containing, in terms of % by mass: 0.02% or less of C; 0.02% or less of N; 0.1% to 1.5% of Si; 1.5% or less of Mn; 0.035% or less of P; 0.010% or less of S; 1.5% or less of Ni; 10% to 20% of Cr; 1.0% to 3.0% of Cu; 0.08% to 0.30% of Ti; and 0.3% or less of Al, with the balance being Fe and unavoidable impurities, and the hot-rolled ferritic stainless steel sheet has a Vickers hardness of less than 235 Hv.
US10072322B2	Aluminum alloy having excellent formability and elasticity and method of producing the same An aluminum alloy having excellent formability and elasticity includes Ti, B, Mg, and the Al, wherein a composition ratio of Ti: B: Mg is 1:3.5˜4.5:1, and AlB2 and TiB2 are present as reinforcing phases.
US10072321B2	Copper nickel alloy The copper alloy of the present invention contains 5% by mass to 25% by mass of Ni, 5% by mass to 10% by mass of Sn, 0.005% by mass to 0.5% by mass of element A (element A being at least one selected from the group consisting of Nb, Zr and Ti), and 0.005% by mass or more of carbon. In the copper alloy, the mole ratio of the carbon to the element A is 10.0 or less. The copper alloy may further contain 0.01% by mass to 1% by mass of Mn. In this copper alloy, the element A may be present as carbide.
US10072320B2	Method of producing steel material A method of producing a steel material includes a step of adding Ca to molten steel with an amount of Ca adjusted within a range satisfying the formula (1) below: 0.5 ≤ { Ca · y ⁢ / ⁢ 100 - ( [ S · W ⁢ / ⁢ 100 ) · 40.08 ⁢ / ⁢ 32.07 } ⁢ 56.08 40.08 ( [ Al 2 ⁢ O 3 ] · W ⁢ / ⁢ 100 ) ≤ 1.5 ( 1 ) where Ca is the amount [kg] of Ca added, y is an yield [%] of Ca, [S] is a concentration [% by mass] of S in the steel before addition of Ca, [Al2O3] is an amount [% by mass] of Al2O3 in the steel before addition of Ca, and W is a weight [kg] of the molten steel.
US10072315B2	Device for individual quench hardening of technical equipment components Device for individual quenching of gears, pinions, bearing rings and other similar components of technical devices, operating in a vacuum furnace installation, whereby the quenching chamber of the installation is fitted with tightly-sealed doors for workpiece loading and unloading. The following elements are fitted inside the quenching chamber: removable table on which an individual workpiece is placed, along with a surrounding set of removable nozzles; the inlet of the quenching chamber features an attached tank supplying the cooling medium to the nozzles—preferably air or nitrogen, or argon or helium, or hydrogen or carbon dioxide, or mixtures thereof—while the outlet of the quenching chamber is connected to the inlet of a tank receiving expanded cooling medium from the chamber; moreover, there is a compressor connected in between the two tanks, ensuring closed-loop flow of the cooling medium.
US10072314B2	Roughly shaped material for induction hardened components and method for producing same A Roughly shaped material for induction hardened components including: a. steel as a base metal including, as a chemical composition, by mass %, C: 0.35% to 0.6%, Si: 0.02% to 2.0%, Mn: 0.35% to 1.5%, Al: 0.001% to 0.5%, Cr: 0.05% to 2.0%, S: 0.0001% to 0.05%, N: 0.003% to 0.0120%, P: 0.03% or less, O: 0.0050% or less, an iron nitride layer having a thickness of 0.1 μm to 50 μm in a depth direction is formed at a surface, and a volume fraction of a γ′ phase, which is a Fe nitride, in the iron nitride layer, is 80% or more.
US10072311B2	Microorganisms from sourdough The invention relates to novel Lactobacillus strains isolated from sourdough. Also encompassed is a composition comprising at least one of said Lactobacillus strains with optionally additional other microorganisms such as bacteria and/or yeasts. The invention further relates to the use of said Lactobacillus strains or compositions for the manufacture of human food products and food supplement products or animal feed products. Another aspect of the invention is the use of the Lactobacillus strains or the composition of Lactobacillus strains in human or veterinary medicine or in cosmetics.
US10072305B2	Real-time PCR for the detection of pathogens Disclosed herein are methods for detecting presence of one or more of Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Toxoplasma gondii, Moraxella catarrhalis, Escherichia coli, Shigella, Staphylococcus aureus, Pneumocystis jirovecii, Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Ureaplasma spp., Bartonella spp., Streptococcus agalactiae, and Neisseria meningitidis nucleic acids in a sample, such as a biological sample obtained from a subject, or an environmental sample. This disclosure also provides probes, primers, and kits for detecting one or more of Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Toxoplasma gondii, Moraxella catarrhalis, Escherichia coli, Shigella, Staphylococcus aureus, Pneumocystis jirovecii, Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Ureaplasma spp., Bartonella spp., Streptococcus agalactiae, and Neisseria meningitidis in a sample.
US10072302B2	Cervical cancer diagnosing method and diagnostic kit for same There are provided an improved cervical cancer diagnosing method and a diagnostic kit for same. According to the present invention, it is possible to more rapidly and accurately provide a patient group requiring a clinical treatment and a prevention treatment in terms of a technical aspect to predict that the limitation of the existing HPV DNA test method can be overcome, automate the RNA extraction from eliminated cells, and more rapidly provide more objective and accurate results because the result analysis can be performed by software by using the real-time RT-PCR.
US10072301B2	Means and methods for molecular classification of breast cancer The invention relates to a method of typing a sample from a breast cancer patient. More specifically, the invention relates to a method for classification of breast cancer according to the presence or absence of Estrogen Receptor (ER), Progesterone Receptor (PR) and Human Epidermal growth factor Receptor 2 (ERBB2; HER2). More specifically, the invention provides methods and means to classify breast cancer as ER positive, triple negative (ER−, PR− and HER2−) and HER2+.
US10072298B2	Gene fusions and gene variants associated with cancer The disclosure provides gene fusions, gene variants, and novel associations with disease states, as well as kits, probes, and methods of using the same.
US10072295B2	Non-invasive fetal genetic screening by digtal analysis The present methods are exemplified by a process in which maternal blood containing fetal DNA is diluted to a nominal value of approximately 0.5 genome equivalent of DNA per reaction sample. Digital analysis is then be used to detect aneuploidy, such as the trisomy that causes Down Syndrome. Since aneuploidies do not present a mutational change in sequence, and are merely a change in the number of chromosomes, it has not been possible to detect them in a fetus without resorting to invasive techniques such as amniocentesis or chorionic villi sampling. Digital amplification allows the detection of aneuploidy using massively parallel amplification and detection methods, examining, e.g., 10,000 genome equivalents.
US10072294B2	Ultra-high sensitive monitoring of early transplantation failure The present invention provides a method for detecting transplantation failure of a transplanted organ or cells which comprises detecting a donor-positive but recipient-negative DNA marker in the recipient's plasma using pyrophosphorolysis activated polymerization. Because of the high sensitivity, specificity and selectivity of pyrophosphorolysis activated polymerization, transplantation failure can be detected at early stages and treatment can be initiate earlier.
US10072285B2	RNA amplification methods Methods of detecting and amplifying short RNAs are provided.
US10072283B2	Direct capture, amplification and sequencing of target DNA using immobilized primers Certain embodiments provide a method for capturing a genomic fragment. The method may comprise: obtaining a substrate comprising a first population of surface-bound oligonucleotides and a second population of surface-bound oligonucleotides; hybridizing a first member of the first population of surface-bound oligonucleotides to a selection oligonucleotide comprising a region that hybridizes with the first member and a region that contains a genomic sequence; extending the first member of the first population of surface-bound oligonucleotides to produce a support-bound selection primer that comprises a sequence that is complementary to the genomic sequence; hybridizing the support-bound selection primer to a nucleic acid fragment comprising the genomic sequence; extending the support-bound selection primer to produce an extension product that contains a sequence that flanks the genomic sequence, e.g., in a genome; and amplifying the extension product on the substrate.
US10072279B2	Method for producing terpenes The present invention concerns a method for producing terpenes in fungi comprising the steps of (a) providing a modified terpene biosynthetic gene cluster inside a host cell, wherein one or more of the naturally occurring genes or promoters of the cluster have been replaced, truncated or removed, (b) providing a transcription factor inside the host cell, the transcription factor activating the terpene biosynthetic gene cluster; (c) cultivating said host in conditions allowing the expression of the transcription factor activating the cluster; and optionally (d) recovering the thus produced terpene product.
US10072274B2	Vector comprising multiple homologous nucleotide sequences The invention relates to vectors comprising two or more homologous nucleotide sequences and methods for generating them. The invention concerns substituting bases in the homologous nucleotide sequences with different bases that do not alter the encoded amino acid sequence. The invention allows for the reduction of intramolecular recombination between homologous nucleotide sequences, in particular in mammalian cells. The invention further relates to nucleotide sequences containing substituted bases.
US10072269B2	Synthetic promoter and methods of use thereof The present invention relates to methods for the design and production of synthetic promoters with a defined specificity and promoters produced with these methods.
US10072268B2	System, method, and device for the expression or repression of proteins This invention relates to systems, methods, and devices for inducing and/or repressing the expression of proteins. More particularly, the invention relates to systems, methods, and devices for inducing and/or repressing the expression of proteins in plastids. An exemplary embodiment involves the regulation of the expression of proteins involved in hydrogen production to stimulate the production of hydrogen gas using the methods, systems, and devices described herein.
US10072266B2	STAT5 inhibitors and use thereof Provided is a composition of matter binding specifically to STAT5, preferably to STAT5B, including a nucleic acid aptamer, and methods of treatment of cancer, and in particular leukaemia via the inhibition of STAT5 protein. The present invention relates more particularly to specific aptamers of STAT5 protein, and the therapeutic or diagnostic use thereof. Also provided is a method for detecting STAT5 in a biological sample, including contacting a nucleic acid aptamer binding specifically to STAT5 with a sample taken beforehand from a subject and determining the quantity of said aptamer bound to said sample.
US10072265B2	Oligomeric compounds and compositions for use in modulation of small non-coding RNAs Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.
US10072259B2	Compositions and methods for nucleic acid extraction Compositions and techniques for the extraction, enrichment and isolation of nucleic acids from yeast in a whole blood sample using amine monomers are disclosed herein.
US10072255B2	Microorganism having regulated expression of (R)-specific enoyl-coa hydratase gene and method for producing polyhydroxyalkanoate copolymer using same This invention relates to a microorganism that produces a polyhydroxyalkanoate (PHA) copolymer with a regulated monomer composition ratio and comprises a (R)-specific enoyl-CoA hydratase gene in the genome DNA, wherein a nucleotide sequence upstream of the (R)-specific enoyl-CoA hydratase gene comprises a modification consisting of a substitution(s), a deletion(s), an insertion(s), and/or an addition(s) of one or a plurality of nucleotides so that the expression of the (R)-specific enoyl-CoA hydratase gene is regulated, and to a method for producing a PHA copolymer using the microorganism.
US10072254B2	Cell culture methods for expressing ADAMTS13 protein The present invention provides culture mediums that are useful for the expression of ADAMTS proteins, such as ADAMTS13. Methods for the expression and purification of ADAMTS proteins are also provided. In some embodiments, the mediums and methods of the invention are useful for the expression of ADAMTS proteins having high specific activities. Also provided are ADAMTS, e.g., ADAMTS13, protein compositions with high specific activities, which are expressed and purified according to the methods provided herein.
US10072252B2	Sulfolobal phosphotriesterase-like (PLL) lactonases activity having enhanced properties and the uses thereof Mutated hyperthermophilic PTE having a lactonase activity derived from a hyperthermophilic phosphotriesterase corresponding to the consensus sequence of SEQ ID NO: 1, the mutated PTE including the at least one mutation chosen amongst 53 putative positions and the mutated PTE having enhanced properties. Also provided are compositions including the mutated hyperthermophilic PTE and the uses thereof, notably as bioscavenger of organophosphate compounds or as quorum quencher of the bacteria using lactones to communicate.
US10072250B2	Method for manufacturing non-enveloped virus The present invention provides a method for efficiently manufacturing a non-enveloped virus with high purity without laborious operation by cultivating cells having the ability to produce a non-enveloped virus and bringing the cells and an acidic solution into contact with each other. A non-enveloped virus vector manufactured by the method of the present invention and a composition having the non-enveloped viral vector as an active ingredient are very useful as gene transfer methods in the fields of basic research and clinical application gene therapy.
US10072249B2	Method of inducing kidney from pluripotent stem cells The purpose of the present invention is to provide a process or method that can be utilized when deriving a three-dimensional structure of a kidney from pluripotent stem cells such as ES cells or iPS cells. The differentiation inducing method is characterized by culturing pluripotent cells with the following three steps, in order: (a) a step of culturing an embryoid body induced from the pluripotent stem cells in medium containing Bmp4 and a high-concentration (concentration A) Wnt agonist; (b) a step of culturing the embryoid body in medium which contains activin, Bmp4, retinoic acid and a middle-concentration (concentration B) Wnt agonist; and (c) a step of culturing the embryoid body in medium containing Fgf9 and a low-concentration (concentration C) Wnt agonist (herein, the Wnt agonist concentrations is concentration A>concentration B>concentration C).
US10072247B2	Composition comprising ischemic serum for promoting activation of stem cell and method for promoting activation of stem cell The present invention relates to a composition comprising an ischemic serum for promoting the activation of a stem cell, to a method for promoting the activation of a stem cell and to a stem cell, the activation of which is promoted by the composition or the method. The ischemic serum according to the present invention may stimulate the stem cell to facilitate the secretion of a growth factor, improve survival rate, improve mobility to an injured part, improve proliferation rate and maintain characteristics of the stem cell, thus promoting an activation of the stem cell such that the stem cell becomes suitable for transplantation of the stem cell to a patient having a brain injury.
US10072246B2	Enhanced generation of cytotoxic T lymphocytes by IL-21 mediated FoxP3 suppression A method of carrying out adoptive immunotherapy by administering a subject an antigen-specific cytotoxic T lymphocytes (CTL) preparation in a treatment-effective amount is described. In the method, the CTL preparation is preferably administered as a preparation of an in vitro antigen-stimulated and expanded primate CTL population, the CTL population: (i) depleted of FoxP3+ T lymphocytes prior to antigen stimulation; (ii) antigen-stimulated in vitro in the presence of interleukin-21; or (iii) both depleted of FoxP3+ T lymphocytes prior to antigen stimulation and then antigen-stimulated in vitro in the presence of interleukin-21. Methods of preparing such compositions, and compositions useful for carrying out the adoptive immunotherapy, are also described.
US10072245B2	Method for generation of a cell composition of mesencephalic dopaminergic progenitor cells The present invention provides a method for generation of a cell composition of mesencephalic dopaminergic progenitor cells from a starting cell composition comprising pluripotent and/or multipotent stem cells, the method comprising the steps of a) differentiating said pluripotent and/or multipotent stem cells into mesencephalic dopaminergic progenitor cells, thereby generating a cell population comprising mesencephalic dopaminergic progenitor cells and other cells, b) dissociating the differentiated cells of step a) into a single cell suspension, and c) enriching said mesencephalic dopaminergic progenitor cells by using an antigen binding molecule specific for the CD47 antigen for positive selection of said mesencephalic dopaminergic progenitor cells in said single cell suspension. Said method may be performed in a closed cell sample processing system and may be performed in an automated manner.
US10072244B2	Method for preparing heterogenetic corneal material Disclosed is a method for preparing a heterogenous corneal material, wherein during the whole preparation process, different concentrations of glycerol are used to achieve that the heterogenous corneal graft has the transparent, properties of no viruses and cells; resistance to degradation and immunogenicity of collagen can be further reduced by collagen cross-linking; and under the whole eye saving, cross-linkers 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide (EDC) and N-hydroxy sulfosuccinimide (NHS) are used for cross-linking, thus enabling the form thereof to be closer to that of a fresh cornea and improving biomechanical properties thereof. The method can prepare a heterogenous corneal material with a high transparency, a low immunogenicity and a good bioactivity and biocompatibility, and can maintain that the three-dimensional structure of collagen is close to that of a fresh cornea. The corneal material prepared by the method is improved in both saving of fibre structure of corneal collagen and transparent performance after transplantation and can be widely used in the medical field.
US10072242B2	Cell sorting method The invention provides a method of removing or reducing undifferentiated cells from a differentiated cell population contaminated or having a risk of contamination with undifferentiated cells by contacting a pigment epithelium-derived factor with the differentiated cell population to induce apoptosis of the undifferentiated cells. The invention also provides an agent for cell transplantation therapy, containing a differentiated cell population substantially free of an undifferentiated cell, which is obtained by the method, as well as an agent for inducing apoptosis of an undifferentiated cell, containing a pigment epithelium-derived factor, and combined use of the aforementioned agent for cell transplantation therapy and the aforementioned agent for inducing apoptosis.
US10072241B2	Conical devices for three-dimensional aggregate(s) of eukaryotic cells Inventive concepts relate generally to the field of cell culture, and more particularly to formation of three-dimensional aggregate(s) of eukaryotic cells. Cell culture vessels including a conical device having an inner surface being hydrophobic; and a frustum defining an open viewing aperture and a narrow end of the conical device are described. Ceil culture vessel arrays, assemblies and kits are described, as well as methods of making and using the devices.
US10072240B2	Method for modular design, fabrication and assembly of integrated biocolumn systems with multiple downstream outputs Present invention relates to a modular system for fabrication of a biocolumn for generating fuel stocks. The biocolumn of independent units called modules and which function as independent units and can be assembled together to fabricate a biocolumn. These modules can be assembled together to form various zones of biocolumn. Fuel stocks can be prepared by inputting a nutrient, a renewable energy source, photon energy and a carbon source into said zones and outputting fuel stock and by products from zones. The zones are interconnected so that byproducts from each zone can be recycled as input or transformed into product.
US10072238B2	Microalgae culture system under external conditions The present invention relates to a microalgae culture system under external conditions that comprises a shallow-depth culture container, a rotation system for the generation of light-darkness cycles and re-suspension, which maximises the photosynthetic efficiency of the microalgae and homogenises the nutrients supplied such that the microalgae may adequately grow in all the areas of the photobioreactor, a gas exchange and temperature control system, which makes it possible to control and maintain the culture parameters under the optimal microalgae growth conditions, a filtration and self-cleaning system, an energy control and saving system, which makes it possible to maintain the desired conditions with the lowest energy expenditure, and a cover system, which filters ultraviolet and/or infrared radiation and makes it possible to control contaminations, the temperature and the evaporation.
US10072236B2	Detergent composition comprising protease variants The present invention relates to detergent compositions comprising protease variants and methods for obtaining such detergent compositions. The present invention also relates to the use of such detergent compositions, especially in laundry or in hard surface cleaning applications.
US10072232B2	Solvent extraction of oil from distillers dried grains and methods of using extraction products A process for extraction of crude oil from distillers dried grain solubles and/or distillers dried grains and producing corn distillers meal that may be used as a livestock supplement is disclosed. For example, the corn distillers meal may be used as a crude protein supplement for use in a livestock feed diet or a poultry feed diet. The solvent extracted crude oil may be suitable for oleochemical processing for personal care and home care products, biodiesel production, and/or renewable diesel production from hydro-treating the extracted oil to make green diesel fuel.
US10072230B2	Method for reducing engine wear with lubricants comprising 2-hydroxyalkylamide friction modifying/anti-wear compositions Lubricant compositions comprising an improved ashless organic friction modifier additive have been found to be capable of reducing both friction and wear. It has been found that mixtures of fatty-alkanolamides containing secondary hydroxyls on the amino alkyl substituent, such as amide mixtures prepared from bis(2-hydroxypropyl)amine and mixtures of at least two different C8-24 fatty acids, provide better oil solubility and friction reduction than alkanolamides with primary, hydroxyl functionality, such as amide mixtures prepared from di-ethanol)amine.
US10072223B2	Feed delivery system and method for gasifier A system for processing material for a gasifier. The system comprises an auger feeder adapted to receive material to be gasified. The auger feeder is adapted to feed the material. In an exemplary embodiment, a tube is connected to the auger feeder such that the tube is adapted to receive the material from the auger feeder. In such an embodiment, the tube is also connected to a gasifier, which is adapted to receive the material from the tube.
US10072222B2	Process for conversion of a hydrocarbon stream In a broad aspect the present disclosure relates to a process plant and a process for upgrading a hydrocarbon mixture, withdrawn as a direct stream from a crude distillation unit and an initial boiling point below 200° C., and a fraction of at least 5% boiling above 500° C., 550° C. or 650° C. comprising the steps of a. directing said hydrocarbon mixture to a vacuum flasher unit, b. withdrawing a heavy hydrocarbon fraction from said vacuum flasher unit, c. withdrawing a light hydrocarbon mixture for hydrocrackingfrom said vacuum flasher unit, d. directing said light hydrocarbon mixture for hydrocracking and a stream rich in hydrogen to con-tact a material catalytically active in hydrocracking, e. withdrawing a hydrocracked stream of hydrocarbon from said hydrocracker. with the associated benefit of limiting the amount of asphaltenes, metals and other heavy components contacting said material catalytically active in hydrocracking.
US10072221B2	Process for the hydrotreatment of a gas oil in a series of reactors with recycling of hydrogen Process for hydrotreatment of hydrocarbon-containing feedstock comprising sulphur- and nitrogen-containing compounds, comprising: a) separating the feedstock into heavy and light fractions, b) a first hydrotreatment stage wherein the heavy fraction and hydrogen are contacted with a first hydrotreatment catalyst Z1 to produce a first desulphurized effluent, c) separating the first effluent into a first gaseous fraction and a first liquid fraction, d) purifying the first gaseous fraction to produce a hydrogen-rich flow, e) mixing the light fraction with the first liquid fraction to produce a mixture, f) a second hydrotreatment stage wherein the mixture from stage e) and the hydrogen-rich flow from stage d) are contacted with a second hydrotreatment catalyst Z2 to produce a second desulphurized effluent, g) separating the second effluent into a second gaseous fraction and a second liquid fraction, h) recycling at least part of the second gaseous fraction to b) as a flow of hydrogen.
US10072216B2	Multiple preflash and exchanger (MPEX) network system for crude and vacuum units Plants and methods are presented for crude feed pre-processing before feeding the crude feed into a crude unit or vacuum unit. Pre-processing is preferably achieved with a combination of a preflash drum and a preflash column that allows for high-temperature treatment of the liquids and separate vapor phase handling, which advantageously enables retrofitting existing plants to accommodate lighter crude feeds.
US10072210B2	Liquid-crystalline medium and liquid-crystal display comprising the same The invention relates to a liquid-crystalline medium, having particular dielectric properties, in that it has: either a dielectric constant perpendicular to the director (ε⊥) in the range of 2 or more to less 8 or less and at the same time a ratio of the dielectric constant perpendicular to the director (ε⊥) to the dielectric anisotropy (Δε), i.e. (ε⊥/Δε) of 1.0 or more or or a dielectric constant perpendicular to the director (ε⊥) of 8 or more and a dielectric anisotropy (Δε) of 26 or less and preferably comprises one or more compounds having a high dielectric constant perpendicular to the director (ε⊥) and a high average dielectric constant (εav.). These compounds are suitable for use in an electro-optical display, particularly in an active-matrix display based on the IPS or FFS effect.
US10072205B2	Methods and systems for acidizing subterranean formations with treatment fluids containing dual-functioning chelating agents When used outside the pH range at which metal ion complexation normally occurs, aminopolycarboxylic acids can moderate the reaction rate of acids with carbonate minerals. Methods for treating a subterranean formation can comprise: providing a treatment fluid comprising an aqueous carrier fluid, an acid, and a chelating agent comprising an aminopolycarboxylic acid, the treatment fluid having a pH below that at which the carboxylic acid groups of the chelating agent are substantially protonated and the chelating agent is ineffective for complexing a metal ion; introducing the treatment fluid into a subterranean formation comprising a carbonate mineral; reacting the acid with the carbonate mineral, such that the acid at least partially spends and the pH of the treatment fluid rises; and once the pH of the treatment fluid rises above a pKa value for one or more of the carboxylic acid groups, complexing a metal ion with the chelating agent.
US10072203B2	Method of increasing scale inhibitor retention A method for increasing the retention of a scale inhibitor within a hydrocarbon producing system by (i) pre-flushing the system with a liquid; (ii) treating the system with a scale inhibitor; and (iii) over-flushing the system with a composition comprising an ionic polymer and a liquid carrier. The concentration of the ionic polymer in the composition is 5 to 50% wt.
US10072195B2	Thermally conductive complex oxide, production method therefor, thermally conductive complex oxide-containing composition, and use therefor The thermally conductive composite oxide of the present invention has excellent physical properties, such as high thermal conductivity, water resistance, acid resistance, electric resistance, and electric insulation, required for coating films, films, and articles thereof. Paints or resins including the composite oxide can provide coating films, films, and articles having such properties without treating of a surface, etc. The composite oxide has a spinel structure and contains aluminum as a main metal component and at least one metal other than aluminum, which is magnesium, zinc, calcium, and/or strontium, and has a ratio (b mol)/(a mol) in a range of 0.1 or more and 1.0 or less, where the ratio (b mol)/(a mol) is a number of moles (b) of the metal other than aluminum to that of moles (a) of an aluminum element derived from an alumina-based compound. The thermally conductive composite oxide has Mohs hardness of less than 9.
US10072194B2	Working fluid for heat cycle To provide a working fluid for heat cycle, which has less influence over the ozone layer and has less influence over global warming, and which has favorable cycle performance. A working fluid for heat cycle, which contains trifluoroethylene and difluoroethylene, wherein the proportion of the content of difluoroethylene is less than 1.5 mass % based on the working fluid.
US10072192B2	Stable formulated systems with chloro-3,3,3-trifluoropropene The present invention relates to formulated refrigerant systems of 1-chloro-3,3,3-trifluoropropene (R-1233zd) that are sufficiently thermally and chemically stable such that they can be effectively used sans additional stabilizers. The formulations of the present invention are particularly useful compositions for refrigeration, heat transfer and foam blowing.
US10072191B2	Composition, system and method for preventing formation of frozen water or for causing the same to melt A de/anti-icer composition comprises one or more de/anti-icer moieties and a marker material, the marker material being selected such that, after application of the de/anti-icer composition to a traveled surface, the amount of the marker material at or on the traveled surface at a given time correlates to the amount of said one or more de/anti-icer moieties on the said surface at such time. The presence of the marker material enables the user readily to determine the concentration of the de/anti-icer moiety or the freezing point of liquid on the traveled surface. Methods of using such compositions for concentration and/or freezing point determination of de/anti-icer materials applied to traveled surfaces are described, together with systems and kits of parts utilizing such compositions.
US10072180B2	Composition for preparing article containing poly(imide-amide), method of preparing the same, and article containing poly(imide-amide) A composition for preparing an article including a poly(imide-amide) copolymer, the composition including (i) a copolymer obtained by reacting a tetracarboxylic acid dianhydride represented by Chemical Formula 1, a diamine represented by Chemical Formula 2, and a carboxylic acid dichloride to form a reaction product, followed by removing hydrochloric acid from the reaction product, (ii) an acid anhydride, and (iii) a solvent: Wherein group R1 in Chemical Formula 1 and group R2 in Chemical Formula 2 are the same as described in the specification.
US10072177B2	Stretchable polymer thick film compositions for thermoplastic substrates and wearables electronics This invention is directed to stretchable polymer thick film compositions useful for wearable garments. More specifically, the polymer thick film may be used in applications where significant stretching is required, particularly on substrates that can be highly elongated. A particular type of substrate is a thermoplastic polyurethane substrate.
US10072174B2	Hard coating composition, and hard coating film, window film and display device comprising the same Described is a hard coating composition composed of a silazane compound, a polyfunctional (meth)acryl-based dendrimer compound or a polyfunctional urethane (meth)acrylate having a cyclohexyl group, a photoinitiator and a solvent, and to a hard coating film, a window film, and a display device including the same, thus exhibiting superior scratch resistance, hardness and flexibility.
US10072171B2	Olefin-based paint containing propylene/α-olefin copolymer The present invention relates to an olefin-based paint. The purpose of the present invention is to provide a paint with excellent organic solvent solubility or dispersibility, low paint viscosity, minimal coating irregularities even at high concentrations, excellent handling and storage stability, and excellent blocking resistance and coated film stability. In order to meet this purpose, an olefin-based paint is used that is characterized by containing a solution or dispersion obtained by dissolving or dispersing 0.1-55 parts by mass of a propylene-α-olefin copolymer (A) for 100 parts by mass of an organic solvent. The copolymer (A) is characterized by containing 60-90 mol % of propylene-derived constituent units (a) having a weight-average molecular weight (Mw), measured by GPC, in the range of 3,000 to 40,000, and 10-40 mol % of α-olefin-derived constituent units (b) having 4 or more carbon atoms [wherein (a)+(b)=100 mol %].
US10072169B2	Inkjet ink and image-forming method The purpose of the present invention is to provide an active ray-curable inkjet ink capable of further enhancing gloss uniformity, surface curability, and scratch resistance of a formed image. The purpose is achieved by an active ray-curable inkjet ink containing a polymerization initiator, a photopolymerizable compound, and a gelling agent, and that undergoes a reversible sol-gel phase transition by temperature change. The inkjet ink contains a polymerization initiator with a molecular weight of 360 or more, and a polyfunctional photopolymerizable compound. The inkjet ink contains 3.0 mass % or more and less than 8.0 mass % of the polymerization initiator with a molecular weight of 360 or more, 1.0 mass % or more and less than 5.0 mass % of the gelling agent, less than 0.1 mass % of the initiator with a molecular weight of 360 or more, and less than 5.0 mass % of the monofunctional photopolymerizable compound.
US10072164B2	Active energy ray-curable inkjet ink composition and printed product An object of the present invention is to provide: a pigment dispersion liquid for inkjet ink, which is stable for a long period of storage and which increases repellency to ink ejection surface. Disclosed is a pigment dispersion liquid for inkjet ink, comprising: a pigment; a pigment dispersing agent; and a compound having an ethylenically unsaturated double bond, wherein the pigment dispersing agent has an amine value of 20 mgKOH/g or less and an acid value of 10 mgKOH/g or less, contains one or more components selected from the group consisting of: a copolymer having a styrene-derived repeating unit, a repeating unit derived from an unsaturated fatty acid having 12 or more carbon atoms, and a repeating unit derived from a polyalkylene oxide having an ethylenically unsaturated double bond; a specific salt of the copolymer and an amine derivative of the copolymer.
US10072162B2	Method of making a cord and polymer jacket assembly having a flame retardant in the polymer jacket material An illustrative method of making an elevator load bearing member having at least one elongated tension member at least partially covered by a jacket includes mixing a flame retardant with a polymer material. The flame retardant is selected from a group consisting of (i) a halogen-free melamine based intumescent comprising melamine cyanurate, melamine-phosphate, melamine pyrophosphate or melamine polyphosphate in an amount up to about 20% by weight of the thermoplastic polymer or (ii) a filled polymer having a nanoscale filler chemically bonded to a matrix phase. Applying the mixed flame retardant and polymer material to the tension member forms a jacket of a desired shape.
US10072160B1	High-durability anti-fouling and anti-icing coatings The invention provides a highly durable surface coating intended to inhibit the formation of ice at sub-0° C. temperatures as well as reduce the accumulation of dirt and insect debris to a vehicle surface upon impact. A continuous, durable matrix surrounds both low-surface-energy (low-adhesion) material inclusions as well as hygroscopic material inclusions. Some variations provide a low-friction, low-adhesion material comprising: a durable continuous matrix; a plurality of first inclusions, dispersed within the matrix, each comprising a low-surface-energy polymer; and a plurality of second inclusions, dispersed within the matrix, each comprising a hygroscopic material. The matrix and the first and second inclusions form a lubricating surface layer in the presence of humidity. Other variations employ a durable continuous matrix and a plurality of inclusions, dispersed within the matrix, each comprising a low-surface-energy polymer surrounding a hygroscopic material. Coating precursors and methods of forming final coatings are also described.
US10072159B2	Coating composition and articles made therefrom The instant invention provides an aqueous dispersion, a coating composition, coating layers and coated article made therefrom. The coating composition according to the present invention comprises: (1) the inventive aqueous dispersion comprising the melt blending product of: (a) from 50 to 99 percent by weight of one or more first polyesters, based on the total solid content of the dispersion, wherein said one or more first polyesters have an acid number in the range of from less than 15, for example less than 10, or in the alternative less than 5, based on the total solid content of the one or more first polyesters; (b) from 1 to 50 percent by weight of one or more stabilizing agents comprising at least one second polyester, based on the total solid content of the dispersion, wherein said second polyester has a carboxylic acid group and an acid number equal to or greater than 15, for example greater than 20, based on the solid content of the second polyester; (c) one or more neutralizing agents; and (d) from 15 to 90 percent by weight of water, based on the total weight of the dispersion; wherein said dispersion has a solid content of 10 to 85 percent, based on the total weight of the dispersion; and (2) one or more cross-linking agents.
US10072156B2	Matte textured powder monocoat coating compositions The present invention includes matte textured powder monocoat coating compositions that can be used to coat substrates, such as automobile bodies, and methods of coating such substrates. A powder coating composition may comprise an acrylic resin, a UV light stabilizer, a matting agent, and a texturing additive, wherein the cured powder coating composition transmits less than about 0.1% of UV light at 290 nm and less than about 0.5% of UV light at 400 nm.
US10072151B2	Room-temperature-curable silicone rubber composition, and the use thereof A room-temperature-curable silicone rubber composition exhibiting good adhesion to a substrate contacted during curing and capable of suppressing the occurrence of oil bleeding is disclosed. The room-temperature-curable silicone rubber composition comprises: (A) a mixture of (A1) an organopolysiloxane having at least two specified alkoxysilyl-containing groups in the molecular and (A2) an organopolysiloxane having one specified alkoxysilyl-containing group in the molecular; (B) an organopolysiloxane lacking a hydroxyl group and an alkoxy group; (C) an alkoxysilane; and (D) a condensation-reaction catalyst.
US10072150B2	Methods and materials for the production of monomers for nylon-4/polyester production This document describes biochemical pathways for producing 4-hydroxybutyrate, 4-aminobutyrate, putrescine or 1,4-butanediol by forming one or two terminal functional groups, comprised of amine or hydroxyl group, in a C5 backbone substrate such as 2-oxoglutarate or L-glutamate.
US10072147B2	Sulfur-containing fuel contact body provided with molded article including polyacetal resin composition having increased acid resistance A polyacetal resin composition makes it possible, when formed into a molded article, to minimize deterioration during contact with sulfur-containing fuel or an acidic detergent. The polyacetal resin composition contains (A) 100 parts by weight of polyacetal resin, (B) 0.1-1.0 parts by weight of hindered phenolic antioxidant, (C) 0.1-2.0 parts by weight of alkaline earth metal oxide, (D) 0.5-3.0 parts by weight of polyalkylene glycol, and (E) 0.01-1.0 parts by weight of polyvalent fatty acid full ester. This polyacetal resin composition minimizes reductions in the weight of a molded article even after the molded article has been immersed in sulfur-containing fuel.
US10072145B2	Thermoplastic moulding compositions with appropriately designed graft shell The invention relates to a thermoplastic molding composition which comprises at least one copolymer component made of styrene monomers and nitrile monomers, and also at least one graft copolymer based on an acrylate rubber. The invention also relates to thermoplastic moldings produced from the thermoplastic molding composition, and the use thereof.
US10072143B2	Aqueous polyolefin resin dispersion Disclosed is an aqueous polyolefin resin dispersion including a polyolefin resin and an aqueous medium, wherein the polyolefin resin includes an olefin component and an unsaturated carboxylic acid component as copolymer components; the olefin component includes propylene (A) and an olefin(s) (B) other than propylene; the mass ratio (A/B) between the propylene (A) and the olefin(s) (B) other than propylene is 60/40 to 95/5; the content of the unsaturated carboxylic acid component as the copolymer component is 1 part by mass or more in relation to 100 parts by mass of the total mass of (A) and (B); and the content of the unsaturated carboxylic acid monomer in the dry residue of the aqueous dispersion is 10,000 ppm or less.
US10072142B2	Stable emulsions of polyisobutene and their use The invention relates to an aqueous polyisobutene emulsion having: 1% wt. to 65% wt., based on the total weight of the emulsion, of polyisobutene, at maximum 5% wt., based on the total weight of the emulsion, of at least one surfactant, and optionally 1% wt. to 65% wt., based on the total weight of the emulsion, of at least one wax and/or oil, complemented with water to 100% wt. The average particle size of the polyisobutene emulsion is not greater than 100 μm. The present invention also relates to the use of such an emulsion.
US10072140B2	Blends of thermoplastic elastomers based on styrene (S-TPE) and polyolefins Polymer blend comprising components A, B and C: A: 1 to 19.5% by weight of an elastomeric block copolymer A based on styrene (S-TPE); B: 0.5 to 8% by weight of a compatibilizer component B; and C: 80 to 98.5% by weight of at least one semi-crystalline olefin homo- or copolymer C. The invention further relates to a composition comprising thermoplastic elastomers based on styrene (S-TPE) for use as compatibilizer of S-TPE block copolymers and polyolefins, a process for the preparation of the polymer blend, a master batch for the preparation of the polymer blend, and single- and multilayer films comprising said polymer blend and their use for food packaging and as shrink hood.
US10072139B2	Process for the preparation of a composition comprising heterophasic propylene co-polymer and talc The invention relates to a Process for the preparation of a composition comprising (A) a heterophasic propylene copolymer, (B) talc and (C) a phenolic antioxidant and/or a processing stabilizer, wherein the heterophasic propylene copolymer consists of (a) a propylene-based matrix, wherein the propylene-based matrix consists of a propylene homopolymer and/or a propylene-α-olefin copolymer consisting of at least 70 wt % of propylene and up to 30 wt % of ethylene, based on the total weight of the propylene-based matrix, wherein the propylene-based matrix is present in an amount of 60 to 95 wt % based on the total heterophasic propylene copolymer and (b) a dispersed ethylene-α-olefin copolymer, wherein the dispersed ethylene-α-olefin copolymer is present in an amount of 40 to 5 wt % based on the total heterophasic propylene copolymer and wherein the sum of the total amount of propylene-based matrix and total amount of the dispersed ethylene-α-olefin copolymer in the heterophasic propylene copolymer is 100 wt %, wherein at least part of the talc is surface-modified and wherein the amount of talc in the composition is from about 0.5 to at most 5 wt % based on the heterophasic propylene copolymer, comprising the step of melt-mixing component (A), component (B) and component (C).
US10072134B2	Polycarbonate-type resin composition and molded article Provided is a polycarbonate-based resin composition, including: (A) a polycarbonate-based resin including 10 mass % to 100 mass % of a specific polycarbonate-polyorganosiloxane copolymer (A-1) and 0 mass % to 90 mass % of a polycarbonate (A-2) except the copolymer (A-1); and (B) an additive, the polycarbonate-based resin composition containing sodium at a content of 0.5 ppm or less.
US10072129B2	Stimuli-responsive polymer composites A polymer composite is provided that includes a plurality of heat-absorbing nanomaterials, a plurality of thermally-expanding microspheres, and an elastomeric matrix. In the polymer composite, the heat-absorbing nanomaterials and the thermally-expanding microspheres are dispersed within the elastomeric matrix such that the thermally-expanding microspheres expand and stretch the matrix upon exposure to a thermal stimulus. Methods of forming a thermally-expanding polymer composite are also provided and include the steps of dispersing a plurality of heat-absorbing nanomaterials in an evaporative solvent; combining the dispersion with an amount of an elastomeric material to create a mixture; adding an amount of thermally-expanding microspheres to the mixture; and polymerizing the mixture. Circuits including resistors comprised of the polymer composites are further provided.
US10072126B2	Soluble nanoparticles for composite performance enhancement A composition may include a resin and a plurality of polymer nanoparticles in the resin to form a resin mixture. The polymer nanoparticles may be soluble or semi-soluble in the resin. At least partial dissolution of the polymer nanoparticles may result in the alteration of one or more of the properties of the resin.
US10072123B2	Polyarylene sulfide production method and polyarylene sulfide A method of producing polyarylene sulfide (PAS) by subjecting a sulfur source and a dihalo aromatic compound (DHA) to polymerization reaction in an organic amide solvent under alkaline conditions, the method suppressing side reactions or the like and yielding PAS having a high degree of polymerization at a high yield is provided; and PAS having a high degree of polymerization are provided.A method of producing PAS, including: a preparation step of preparing a preparation mixture containing an organic amide solvent, a sulfur source, an alkali metal hydroxide, water, and DHA, and having a pH of 12.5 or higher; a first-stage polymerization step of heating the preparation mixture to 170° C. or higher to initiate a polymerization reaction and continuing the polymerization reaction at 240 to 280° C., thereby forming a prepolymer having a DHA conversion rate of 50% or greater (at this time, a temperature increasing rate from 220° C. to 240° C. is lower than a temperature increasing rate for 240° C. or higher); and a second-stage polymerization step of adding, in the reaction system, an alkali metal hydroxide in an amount of 1 to 20 mol % per 1 mol of the sulfur source in the presence of a phase separation agent to continue the polymerization reaction at 245 to 290° C. PAS having a melt viscosity (310° C.; shear rate: 1216 sec−1) of 0.1 to 8000 Pa·s produced by the method.
US10072120B2	Functionalized polyhydroxyalkanoate materials formed from an unsaturated polyhydroxyalkanoate material A process of forming a functionalized polyhydroxyalkanoate (PHA) material includes performing an oxide elimination reaction (e.g., a selenoxide elimination reaction or a sulfoxide elimination reaction) on a saturated PHA material to form an unsaturated PHA material having a carbon-carbon double bond in a polymer backbone. The process also includes utilizing the unsaturated PHA material to form a functionalized PHA material. The functionalized PHA material has one or more cross-linkable functional groups (e.g., one or more thiol groups) bonded to a polymer backbone of the functionalized PHA material.
US10072119B2	Process for enhancing the molecular weight of a polyester The molecular weight of a semi-crystalline starting polyester comprising ethylene 2,5-furandicarboxylate units is enhanced by heating the semi-crystalline starting polyester, having a melting point Tm, at a temperature in the range of (Tm-40° C.) to Tm to obtain a solid stated polyester, where the semi-crystalline starting polyester has an intrinsic viscosity of at least 0.45 dL/g, and an amount of carboxylic acid end groups in the range of 15 to 122 meq/kg.
US10072116B2	Modified propylene-(α-olefin) copolymer, method for producing same, coating material comprising same, resin composition for molding use, and hot-melt composition The purpose of the present invention is to provide a polar-group-containing propylene-type wax having excellent properties including a low melting point. A modified propylene-(α-olefin) copolymer (A) according to the present invention is produced by grafting at least one compound selected from an unsaturated carboxylic acid, a derivative of the unsaturated carboxylic acid and an unsaturated sulfonic acid salt onto a propylene-(α-olefin) copolymer (A1) and has an acid value of 1 to 100 KOHmg/g, wherein the propylene-(α-olefin) copolymer (A1) comprises 60 to 95 mol % of a propylene-derived constituent unit (a) and 5 to 40 mol % of a constituent unit (b) derived from an α-olefin having 4 or more carbon atoms, and satisfies the specific requirements (i) to (iii).
US10072114B2	Method for producing modified conjugated diene polymer, polymer composition, crosslinked polymer and tire A modified conjugated diene polymer obtained by modifying a conjugated diene polymer that is obtained by polymerizing a conjugated diene compound or polymerizing a conjugated diene compound and an aromatic vinyl compound is produced by a production method comprising a first modification step wherein an unsaturated binding site at least either in the skeleton or at the side chain of the conjugated diene polymer is reacted with a first compound having a group 4 or 13 element of the periodic table.
US10072110B2	Propylene-based elastomer Provided is a propylene-based elastomer having a narrow molecular weight distribution, a high density in the same comonomer content, and excellent mechanical properties. The propylene-based elastomer includes 50% by weight or more of a propylene-based repeating unit, and satisfies a particular relationship between an ethylene content and a molar ratio of a specific monomer sequence.
US10072107B2	Long chain branched polypropylene A process for preparing a long chain branched polypropylene in presence of two metallocene-based active catalyst systems is provided. The polypropylene obtained therefrom has new molecular architecture and improved elasticity properties. The polypropylene is further characterized by new signals in its 13C NMR spectrum.
US10072105B2	Method for manufacture of low emissions polypropylene The present invention relates to a method for the manufacture of polypropylene having a target melt flow rate of from 10 to 200 g/10 min as determined in accordance with ISO 1133 (230° C., 2.16 kg) comprising the sequential steps of i) polymerizing propylene monomer, and optionally one or more alpha olefin co-monomers so as to form a polypropylene having an initial melt flow rate of from 0.5 to 20 g/10 min (ISO 1133, 230° C., 2.16 kg), ii) visbreaking said polypropylene to obtain polypropylene having said target melt flow rate and wherein the ratio of target to initial melt flow rate is more than 1 iii) maintaining the polypropylene obtained from step ii) at an elevated temperature for a time sufficient to reduce the FOG value of the polypropylene as determined in accordance with VDA 278. The method allows the time for FOG reduction to be reduced as compared to polypropylenes that have the same target melt flow rate, yet which have obtained said melt flow rate without the visbreaking step.
US10072104B2	Polymer backbone element tags Element tags based on novel metal-polymer conjugates are provided for elemental analysis of analytes, including ICP-MS. A polymer backbone is functionalized to irreversibly bind metals that are selected prior to use by the user. The polymer is further functionalized to attach a linker which allows for attachment to antibodies or other affinity reagents. The polymer format allows attachment of many copies of a given isotope, which linearly improves sensitivity. The metal-polymer conjugate tags enable multiplexed assay in two formats: bulk assay, where the average biomarker distribution in the sample is diagnostic, and single cell format to distinguish a rare (for example a diseased) cell in a complex sample (for example, blood).
US10072101B2	Cycloolefin rubber and method of production of same and rubber composition, cross-linked rubber, and tire A cycloolefin rubber having a weight average molecular weight of 100,000 to 800,000, having a silyl group at the polymer chain end, and containing a fatty acid ester of a polyvalent alcohol. A cycloolefin rubber excellent in processability at the time of blending and kneading and excellent in low heat buildup property can be provided.
US10072099B2	Process for the organosolv treatment of lignocellulosic biomass The present invention is directed at a process for fractionating lignocellulosic biomass for the purpose of reducing processing costs, increasing delignification, reducing side-reactions, in particular reducing hemicelluloses degradation, improving cellulose hydrolysis and increasing the nativity of the obtained lignin, by performing organosolv fractionation of the biomass with a treatment liquid at a temperature below 170° C., wherein the treatment liquid comprises a non-hydroxylic organic solvent, in particular a ketone, water and some acid, and optionally subjecting the cellulose-enriched product stream to enzymatic hydrolysis.
US10072097B2	Compositions and methods for detection of protein S-nitrosylation and oxidation The present invention discloses a novel isolated antibody that specifically binds to an N-phenyl-acetamide group. Also disclosed are related compositions, kits, methods for detecting protein S-nitrosylation or oxidation vivo or in vitro, and drug screening methods.
US10072093B2	Fusion protein to target and treat acute myeloid leukemia cells A polypeptide which binds to the surface of AML blast cells and is internalized upon binding to the AML blast cells.
US10072088B2	Anti-BCMA antibodies and uses thereof Provided herein are antibodies that immunospecifically bind to BCMA. Also described are related polynucleotides capable of encoding the provided BCMA-specific antibodies or antigen-binding fragments, cells expressing the provided antibodies or antigen-binding fragments, as well as associated vectors and detectably labeled antibodies or antigen-binding fragments. In addition, methods of using the provided antibodies are described. For example, the provided antibodies may be used to diagnose, treat, or monitor BCMA-expressing cancer progression, regression, or stability; to determine whether or not a patient should be treated for cancer; or to determine whether or not a subject is afflicted with BCMA-expressing cancer and thus may be amenable to treatment with a BCMA-specific anti-cancer therapeutic, such as the multispecific antibodies against BCMA and CD3 described herein.
US10072085B2	Method of treating psoriasis using an IL-17 receptor antibody formulation The present disclosure relates to ΛM-14 pharmaceutical formulations and therapeutic dosing regimens for the treatment of disease.
US10072084B2	Dual specific immunotoxin for brain tumor therapy We tested the in vitro and in vivo efficacy of a recombinant bispecific immunotoxin that recognizes both EGFRwt and tumor-specific EGFRvIII receptors. A single chain antibody was cloned from a hybridoma and fused to toxin, carrying a C-terminal peptide which increases retention within cells. The binding affinity and specificity of the recombinant bispecific immunotoxin for the EGFRwt and the EGFRvIII proteins was measured. In vitro cytotoxicity was measured. In vivo activity of the recombinant bispecific immunotoxin was evaluated in subcutaneous models and compared to that of an established monospecific immunotoxin. In our preclinical studies, the bispecific recombinant immunotoxin, exhibited significant potential for treating brain tumors.
US10072081B2	Anti-CTLA4, anti-GLUT2 protein for the treatment of type 1 diabetes The disclosure relates to a protein composed of a first polypeptide or polypeptide domain having a first specific binding activity for Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) expressed on a T-cell cell surface and a second specific binding activity for Glucose Transporter 2 (GLUT2) or an extracellular ectodomain thereof expressed on a pancreatic β-cell surface, wherein binding of the first polypeptide or polypeptide domain to CTLA-4 induces a CTLA-4 specific agonist response in the T-cell, and binding of the second polypeptide or polypeptide domain to GLUT2 or an ectodomain thereof does not inhibit GLUT2 glucose transporter function, wherein said agonist response in the T-cell induces a response that reduces immunoreactivity against pancreatic β-cells.
US10072075B2	Optimized variants of anti-VEGF antibodies and methods of treatment thereof by reducing or inhibiting angiogenesis The present invention provides anti-VEGF antibodies and compositions that include anti-VEGF antibodies (e.g., antibody conjugates, fusion proteins, and polymeric formulations), and uses thereof, for example for treatment of disorders associated with pathological angiogenesis. The present invention also provides methods of identifying antibody variants with improved properties, for example, enhanced binding affinity, stability, pharmacokinetics, and/or expression.
US10072072B2	Antibody neutralizing human respiratory syncytial virus The present invention relates to monoclonal antibodies which have high anti-RSV neutralizing titers. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. The invention yet further provides for diagnostic, prophylactic and therapeutic methods employing the antibodies and nucleic acids of the invention, particularly as a passive immunotherapy agent in infants and the elderly.
US10072070B2	Potent anti-influenza A neuraminidase subtype N1 antibody Isolated monoclonal antibodies and antigen binding fragments thereof that specifically bind neuraminidase (NA) of an N1 subtype influenza virus are disclosed herein. These antibodies and antigen binding fragments can be used for the detection of an N1 subtype influenza virus and for determining the immunogenicity of vaccines. The antibodies and antigen binding fragments also can be used for the treatment of a subject to prevent or ameliorate an influenza infection.
US10072069B2	Humanized monoclonal antibodies from a transgenic rat The invention relates to transgenic animals lacking endogenous Ig and capable of producing transgenic antibodies, as well as methods of making the same. The invention further relates to methods for producing transgenic antibodies in such animals, and transgenic antibodies so produced.
US10072064B2	Composition comprised of antigen linked to a TNF superfamily ligand The invention provides fusion proteins comprising antigens of infectious disease agents and cancer cells linked to multiple-trimer forms of TNF SuperFamily (TNFSF) ligands. The TNFSFs serve as vaccine adjuvants for increasing the immune response to the antigens. In particular, a fusion polypeptide strand that self-assembles inside cells into a multiple-trimer form of CD40 ligand (CD40L, TNFSF5) is provided. Other similar fusion proteins are also disclosed. The fusion proteins can be delivered to a host as isolated proteins, as nucleic acids used directly in DNA vaccination or carried and expressed by a viral vector such as adenovirus. In addition to use as a vaccine to prevent or ameliorate disease caused by an infectious agent, compositions of the invention may be used for the treatment of ongoing infection or for cancer immunotherapy.
US10072063B2	Peptides and combination of peptides for use in immunotherapy against various tumors The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10072061B2	Tumor targeted TNF-related apoptosis inducing ligand fusion polypeptide, methods and uses therefor Fusion polypeptides comprising a TRAIL trimer and a targeting domain are disclosed. The targeting domain can be, in some embodiments, a sequence that binds MUC16, which is prevalent on some tumor cells such as pancreatic and ovarian tumor cells. A sequence that binds MUC 16 can be mesothelin or a MUC16-binding fragment thereof, such as amino acids 1-64 of mesothelin. A fusion polypeptide of the present teachings can induce apoptosis in a target cell such as a MUC16-expressing cancer cell. Also disclosed are nucleic acids encoding the fusion polypeptides, and methods of use of the fusion polypeptides and nucleic acids.
US10072060B2	Islet amyloid polypeptides with improved solubility Isolated non-naturally occurring, mutant-human islet amyloid polypeptides (hIAPP) are disclosed. These polypeptides can be formulated or co-formulated at physiological pH, which enable the polypeptides of the instant disclosure to be delivered to a subject having an amyloid-based disease in a single injection with an insulin agent. Methods and compositions for treating amyloid-based disease in a subject in need thereof, by administering an effective amount of an isolated, mutant-hIAPP polypeptide, including formulations or co-formulations thereof are also disclosed.
US10072058B2	Chimeric virus-like particles incorporating fusion GPI anchored GM-CSF and IL-4 conjugates This disclosure relates to a GM-CSF and IL-4 conjugate fused to a glycolipid (GPI)-anchoring sequence that is incorporated into chimeric virus-like particles (VLPs) enriched with a viral protein, e.g., viral envelope protein or HIV envelope protein. In certain embodiments, the disclosure relates to methods of immunization with the chimeric VLPs disclosed herein. In certain embodiments, the disclosure relates to methods of immunization with disclosed HIV antigen containing VLPs through an intramuscular priming-intranasal boosting immunization route.
US10072056B2	Proteins specific for pyoverdine and pyochelin The present disclosure provides hNGAL muteins that bind a pyoverdine family member or pyochelin and can be used in various application including pharmaceutical applications, for example, to inhibit or reduce growth of P. aeruginosa. The present disclosure also concerns methods of making one or more pyoverdine- or pyochelin-binding muteins described herein as well as compositions comprising one or more of such muteins. The present disclosure further relates to nucleic acid molecules encoding such muteins and to methods for generation of such muteins and nucleic acid molecules. In addition, the application discloses therapeutic and/or diagnostic uses of these muteins as well as compositions comprising one or more of such muteins.
US10072055B2	Anti-inflammatory pharmaceutical products Polypeptides having homology to regions of the N-terminal 50 residues of human Annexin 1 are provided for medical use as anti-inflammatory agents. Some of the polypeptides have homology to the N-terminal 48 residues of human Annexin 1, especially to residues 2-48 and 11-48 thereof. In some embodiments, properties of these compounds are improved by at least one modification at residues corresponding to residues 11, 22, 25 and/or 36 of human Annexin 1, and/or by C-terminal amidation of the polypeptide. Analogs of amino acids 2-26 of human Annexin 1, especially acetylated at the N-terminus and/or amidated at the C-terminus and having modifications at 11 and/or 22 are also disclosed for medical use as anti-inflammatory agents.
US10072051B2	Anti-inflammatory lipopeptide and preparing method and application thereof Disclosed is an anti-inflammatory lipopeptide, which comprises peptide chains and aliphatic chains, the peptide chain being linked to the aliphatic chain through a peptide bond, and an aliphatic acid being linked to the N-terminus of the peptide chain. The lipopeptide suppresses inflammatory response induced by poly(I:C), so as to prevent inflammation after skin injury and alleviate inflammatory response of skin inflammation such as allergic dermatitis. Also disclosed is a preparing method of the lipopeptide.
US10072048B2	Astexin peptides Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticaccaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticaccaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides.
US10072047B2	Tagged hepadnavirus e antigen and its use in screening antiviral substances The present invention relates to methods and uses for screening anti-hepadnaviral substances, wherein the substances are screened for the capacity to inhibit covalently closed circular (ccc) DNA of a hepadnavirus, like hepatitis B virus. The methods and uses take advantage of cells comprising a nucleic sequence encoding a tagged hepadnavirus e antigen, like Hepatitis B virus e antigen (HBeAg). Furthermore, the present invention provides nucleic acid sequences encoding a tagged hepadnavirus e antigen and proteins encoded thereby. Also kits for use in the screening methods are provided.
US10072037B2	Method for producing high purity lignin The method is for separation of lignin from original black liquor (BLIN) that has a first precipitation stage (PR) for precipitation of lignin by a first acidification using acidifier AC1, preferably using CO2, at alkaline conditions, then separating a lignin cake with subsequent suspension of the lignin cake in a strong acid in order to leach our metals from the lignin followed by dewatering and obtaining a clean lignin product LP. The process further is improved by intensified hydrolysis of lignin cake such that most of the carbohydrates are broken down to dissolvable monomers that could be separated from the lignin in the filtrate from a filtering stage subsequent to the hydrolysis. The improved hydrolysis could reduce as much as 90% of the carbohydrate content using a moderately increased temperature and increased charge of acidifier while avoiding any larger lignin yield losses.
US10072035B2	Phenanthroline phosphonic acid derivative and preparation method therefor and application thereof The present invention relates to a novel phenanthroline phosphonic acid compound and a pharmaceutical salt thereof, as well as an application of the compound and the pharmaceutical salt thereof as collagen prolyl hydroxylase inhibitors in the preparation of drugs for preventing or treating collagen prolyl-4-hydroxylase related disease.
US10072032B2	AminoBisPhosphonate antiwear additives The present invention relates to novel aminobisphosphonate compounds useful as antiwear and/or friction modifier additive components, lubricant additive compositions and lubricant compositions each comprising such compounds, and methods for making and using the same.
US10072029B2	Crystalline form of a proteasome inhibitor The present disclosure relates to a novel crystalline form of a proteasome inhibitor, and to the processes for the preparation thereof. The novel crystalline form according to the disclosure may be used in the preparation of pharmaceutical compositions for the treatment of cancer.
US10072028B2	Cross-coupling of unactivated secondary boronic acids Provided are methods for site- and stereo-retentive cross-couplings with unactivated secondary boronic acids, which methods are particularly useful in building block-based approach for small molecule synthesis. Also provided is a method of forming an air-stable chiral secondary boronic acid.
US10072027B2	Preparation of high-purity gadobutrol What is described is a process for producing high-purity gadobutrol in a purity (according to HPLC) of more than 99.7 or 99.8 or 99.9% and the use for preparing a pharmaceutical formulation for parenteral administration. The process is carried out using specifically controlled crystallization conditions. The more recent developments in the field of the gadolinium-containing MR contrast agents (EP 0448191 B1, CA Patent 1341176, EP 0643705 B1, EP 0986548 B1, EP 0596586 B1) include the MRT contrast agent gadobutrol (Gadovist® 1.0) which has been approved for a relatively long time in Europe and more recently also in the USA under the name Gadavist®.
US10072026B2	Crystalline form of 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile The invention provides a crystalline form of the compound of formula: that is an inhibitor of JAK kinases. The invention also provides pharmaceutical compositions comprising such crystalline form and methods of using such crystalline form in mammals suffering from inflammatory bowel diseases.
US10072023B2	Diarylethene compounds and uses thereof A compound according to Formula IA and IB, reversibly convertible under photochromic and electrochromic conditions between a ring-open isomer A and a ring-closed isomer B is provided. For substitutent groups, Z is N, O or S; each R1 is independently selected from the group consisting of H, or halo; each R2 is independently selected from the group consisting of H, halo, a polymer backbone, alkyl or aryl; or, when both R2 together form —CH═CH— and form part of a polymer backbone; each R3 is independently selected from the group consisting of H, halo, alkyl, alkoxy, thioalkyl or aryl; each R4 is aryl; and each R5 is independently selected from the group consisting of H, halo, alkyl, alkoxy, thioalkyl or aryl.
US10072022B2	Oridonin analogs, compositions, and methods related thereto Certain embodiments are directed to oridonin analogs or derivatives. In certain aspects, the derivatives are used as anticancer or anti-inflammatory agents.
US10072018B2	Compounds for treatment of pain The aspects of the disclosed embodiments are directed to novel compounds, specifically, quaternary ammonium derivatives of tertiary amine containing opioid drug compounds such as hydrocodone, hydromorphone and oxycodone, formulations containing said. compounds or pharmaceutically acceptable salts thereof, which are capable of providing controlled release of the opioid drug upon administration to a patient in order to treat pain.
US10072016B2	Substituted 4-phenylpiperidines, their preparation and use The present invention provides a compound having the structure: wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl, wherein two or more of R1, R2, R3, R4, or R5 are other than H; R6 is H, OH, or halogen; and B is a substituted or unsubstituted heterobicycle, wherein when R1 is CF3, R2 is H, R3 is F, R4 is H, and R5 is H, or R1 is H, R2 is CF3, R3 is H, R4 is CF3, and R5 is H, or R1 is Cl, R2 is H, R3 is H, R4 is F, and R5 is H, or R1 is CF3, R2 is H, R3 is F, R4 is H, and R5 is H, or R1 is CF3, R2 is F, R3 is H, R4 is H, and R5 is H, or R1 is Cl, R2 is F, R3 is H, R4 is H, and R5 is H, then B is other than or a pharmaceutically acceptable salt thereof.
US10072008B2	Spiro-isoquinoline-3,4′-piperidine compounds having activity against pain The present invention relates to compounds having pharmacological activity towards the sigma (σ) receptor, and more particularly to spiro-isoquinoline-3,4′-piperidine compounds having this pharmacological activity, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.
US10071997B2	Pesticidally active amide heterocyclic derivatives with sulphur containing substituents Compounds of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.
US10071994B2	N-sulfonyl homoserine lactone derivatives, preparation method and use thereof The invention relates to a homoserine lactone derivative of Formula I, preparation method and use thereof. The compound has an effect of regulatory of bacterial quorum sensing, and is useful for preventing and/or treating a disease caused by infection of a bacterium
US10071992B2	Diacylglycerol acyl transferase 2 inhibitors Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
US10071991B2	Substituted pyridine derivatives useful as c-fms kinase inhibitors The present invention is directed to substituted pyridine derivatives, pharmaceutical compositions containing said derivatives and the use of said derivatives in the treatment of disorders mediated by c-fms kinase. The present invention is further directed to a process for the preparation of said substituted pyridine derivatives.
US10071988B2	Substituted 1,2,3-triazoles as NR2B-selective NMDA modulators Substituted 1,2,3-triazoles as NR2B receptor ligands. Such compounds may be used in NR2B receptor modulation and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by NR2B receptor activity.
US10071986B2	Substituted pyrroles active as kinases inhibitors The present invention relates to substituted pyrrole compounds which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular Jak family kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them.
US10071985B2	Therapeutic compounds The present disclosure relates to a compound of formula (Ia), (Ib), (IIa), and (IIb): which are useful in the treatment of a Retroviridae viral infection including an infection caused by the HIV virus.
US10071984B2	Histone demethylase inhibitors The present invention relates generally to compositions and methods for treating cancer and neoplastic diseases. Provided herein are substituted imidazole-pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of histone demethylase enzymes. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as pancreatic cancer, prostate cancer, breast cancer, bladder cancer, lung cancer, gastric cancer, leukemia and/or melanoma and the like.
US10071980B2	Agonists that enhanced binding of integrin-expressing cells to integrin receptors A method of enhancing binding of cells to an integrin-binding ligand comprises treating integrin-expressing cells in vitro with an agonist of integrin, wherein the integrin is selected from the group consisting of α4β1, α5β1, α4β7, αvβ3 and αLβ2, and contacting the treated cells with an integrin-binding ligand; integrin agonist compounds having the general formula I; methods of treating integrin-expressing cells with such agonists to enhance binding; and therapeutic methods comprising administering agonist-treated cells or agonist compounds to a mammal.
US10071972B2	Process for the preparation of triazine carbamates This invention relates to a process for the preparation of triazine carbamates by reacting a mixture of an aminotriazine A having at least two amino groups per molecule, an organic carbonate C, and a base B selected from the group consisting of alkoxides, and arylalkoxides of metals M, which may be alkali or earth alkali metals, and a solvent S which is a monohydric alcohol solvent R2OH or a mixture of solvents that comprises a monohydric alcohol R2OH, and a monohydric alcohol R3OH, or a mixture of solvents that comprises a monohydric alcohol R2OH with a further solvent selected from the group consisting of ether, alcohol, and hydrocarbon solvents, and adding to the products of the said reaction, an acid or a solution of an acid in a solvent.
US10071971B2	Substituted [1,2,4]triazole compounds and their use as fungicides The present invention relates to compounds of the formula I wherein the variables are defined in the description and claims, their preparation and uses thereof.
US10071967B2	N-cycloalkyl-N-{[2-(1-substitutedcycloalkyl)phenyl]methylene}-(thio)carboxamide derivatives The present invention relates to fungicidal N-cycloalkyl-N-{[2-(1-substitutedcycloalkyl)phenyl]methylene} carboxamide derivatives and their thiocarbonyl derivatives, their process of preparation and intermediate compounds for their preparation, their use as fungicides, particularly in the form of fungicidal compositions and methods for the control of phytopathogenic fungi of plants using these compounds or their compositions.
US10071966B2	Drug for inhibiting aggregation of proteins involved in diseases linked to protein aggregation and/or neurodegenerative diseases The present invention relates to a compound represented by formula (E). The present invention also relates to a compound represented by the formula (E) for use in the treatment or prevention of diseases linked to protein aggregation and/or neurodegenerative diseases. Moreover, the present invention relates to pharmaceutical and diagnostic compositions comprising the compound of the invention as well as to a kit. Furthermore, the present invention relates to a method of imaging deposits of aggregated protein. A kit for preparing a detectably labelled compound of the present invention is also disclosed.
US10071964B2	Disubstituted piperidines as butyrylcholinesterase inhibitors This invention relates to new inhibitors of butyrylcholinesterase with general formulas I and II, where substituents are described in patent description. Compounds can be in the form of pure enantiomers or as racemic mixtures, or in the form of pharmaceutically acceptable salts. The present invention relates to the use of these inhibitors for the treatment of Alzheimer's disease and other forms of dementia.
US10071963B2	Polymorphic form of N-[2-(6-fluoro-1H-indol-3-yl)ethyl]-3-(2,2,3,3-tetrafluoropropoxy)benzylamine hydrochloride for the treatment of Alzheimer's disease The present invention relates to a novel polymorphic form of N-[2-(6-fluoro-1H-indol-3-yl)ethyl]-3-(2,2,3,3-tetrafluoropropoxy)benzylamine hydrochloride.
US10071962B2	Androgen receptor modulators and methods for their use Compounds having a structure of Structure I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R4, R6, Y1 and Y2 are as defined herein, and wherein at least one of R3 or R4 is a straight-chain C1-C6 haloalkyl, are provided. Uses of such compounds for treatment of various indications, including prostate cancer, as well as methods of treatment involving such compounds are also provided.
US10071953B2	Bifunctional AKR1C3 inhibitors/androgen receptor modulators and methods of use thereof The invention includes compositions comprising selective AKR1C3 inhibitors. The invention also includes compositions comprising bifunctional AKR1C3 inhibitors and selective androgen receptor modulators. The invention further includes methods of treatment using the compositions of the invention.
US10071950B2	Use of immobilized molybdenum- and tungsten-containing catalysts in olefin cross metathesis Method of forming an olefin from a first olefin and a second olefin in a metathesis reaction, comprising step (i): (i) reacting the first olefin with the second olefin in the presence of a silica supported Mo- or W-alkylidene catalyst, wherein the first olefin and the second olefin are different from one another.
US10071925B2	Induced sludge bed anaerobic reactor An induced sludge bed anaerobic reactor includes a vessel in which a septum is positioned to maintain solids in wastewater being treated toward a lower portion of the reactor. The septum is configured to prevent or minimize rising bacteria from exiting the vessel and to minimize clogging of the vessel. A first example septum is disclosed that is based on a linear vane design. A second example septum is disclosed that is based on a concentric vane design. A third example septum is disclosed that is based on a radial vane design that may include one or more sections. Further, septums may be layered one atop another to further minimize rising bacteria from exiting the vessel and to further minimize clogging of the vessel. Finally, a septum is attached to the inside of the vessel so as to allow it to move allowing any clogging waste floating under the septum to exit the vessel.
US10071921B2	Electrochemical reactor system for treatment of water An upright reactor body with a perforated interior tube member which extends for the length of the reactor body. A water inlet permits water to be treated into the perforated tube member. A fibrous metal anode surrounds the perforated tube member followed by a surrounding layer of dielectric and then a surrounding metal cathode layer, wherein water from the inlet passes radially through the perforations in the tube member, through the anode, dielectric and cathode members, emerging from the reactor body through an outlet. A DC voltage is imposed on the cathode and anode.
US10071913B2	Graphene laminate and method of preparing the same A graphene laminate including a substrate, a binder layer on the substrate, and graphene on the binder layer, wherein the graphene is bound to the substrate by the binder layer.
US10071908B2	Burner with only oxidation reaction space for reactor with only reduction reaction space The present disclosure provides a burner for a reduction reactor, the reduction reactor has a reaction space formed therein, wherein each burner has a fuel feeding hole and multiple oxygen feeding holes formed therein, wherein each burner has an elongate combustion space formed at one end of a head portion thereof, the combustion space fluid-communicating with the reaction space of the reactor, wherein the elongate combustion space has a length such that oxygen supplied from the oxygen feeding holes thereto is completely consumed via oxidation or combustion with fuels supplied from the fuel feeding hole thereto only in the elongate combustion space upon igniting the burner.
US10071902B2	Method for assembling conductive particles into conductive pathways and sensors thus formed A sensor is achieved by applying a layer of a mixture that contains polymer and conductive particles over a substrate or first surface, when the mixture has a first viscosity that allows the conductive particles to rearrange within the material. An electric field is applied over the layer, so that a number of the conductive particles are assembled into one or more chain-like conductive pathways with the field and thereafter the viscosity of the layer is changed to a second, higher viscosity, in order to mechanically stabilize the material. The conductivity of the pathway is highly sensitive to the deformations and it can therefore act as deformation sensor. The pathways can be transparent and is thus suited for conductive and resistive touch screens. Other sensors such as strain gauge and vapor sensor can also be achieved.
US10071899B2	Apparatuses, systems, and methods for dispensing condiments Apparatuses, systems, and methods are for dispensing condiments, including a base condiment together with and at least one additive. In some examples, a dispenser apparatus comprises a dispenser body having an upstream inlet that is configured to receive the base condiment and a downstream outlet that is configured to dispense the base condiment together with the additive(s). An additive body is configured to supply the additive(s) into the dispenser body as the base condiment is conveyed from the upstream inlet to the downstream outlet so that the base condiment and the additive(s) are concurrently dispensed via the downstream outlet. The systems and methods can operatively include arrangements for selecting a base condiment; selecting one or more additives from a plurality of additives; and supplying the base condiment and the additive(s) to a dispenser apparatus that dispenses the base condiment and additive(s) together.
US10071896B2	Exhaust valve assembly for a bottle attachment apparatus An exhaust valve assembly for a bottle attachment apparatus for handling liquids has a valve housing which forms a valve chamber having an inlet and an outlet, an exhaust valve body disposed on the inlet in the valve chamber, and a safety valve body disposed on the outlet in the valve chamber. The exhaust valve body is biased toward an exhaust valve seat, counter to the flow direction of the liquid and the safety valve body is biased toward a safety valve seat in the flow direction of the liquid. The safety valve seat is integrally molded on the valve housing.
US10071894B2	Oscillation damping for a material handling vehicle Various embodiments provide a material handling vehicle (MHV) and associated method provide for damping of mast oscillations of a mast of the MHV. In one approach, mast oscillations can be detected and/or anticipated and a countering force can be generated by an elevated reach actuator of the MHV to damp the oscillations.
US10071893B2	Shopping facility assistance system and method to retrieve in-store abandoned mobile item containers A central computer system identifies a mobile item container in a retail shopping facility as being abandoned. The central computer system then directs a motorized transport unit through the retail shopping facility to the abandoned mobile item container and causes that motorized transport unit to physically attach to the abandoned mobile item container. The central computer system then directs that motorized transport unit through the retail shopping facility with the attached abandoned mobile item container to a specified destination within the retail shopping facility. Abandonment can be determined as a function, at least in part, of determining that the mobile item container is both stationary and unattended for at least a predetermined amount of time. By one approach the central computer system can use different predetermined amounts of time when assessing abandonment depending upon where in the retail shopping facility the mobile item containers are located.
US10071892B2	Apparatus and method of obtaining location information of a motorized transport unit Methods and apparatuses are provided, some apparatuses comprise: a location controller separate from a motorized transport unit, comprising: a transceiver configured to receive communications from the motorized transport unit; a control circuit; a memory storing computer instructions that when executed by the control circuit cause the control circuit to perform the steps of: obtain, from the communications, a unique light source identifier of a light source detected by the motorized transport unit, and relative distance information determined by the motorized transport unit through an optical measurement; process the at least one unique light source identifier and the relative distance information relative to a mapping of the shopping facility; and determine, in response to the processing, a location of the motorized transport unit within the shopping facility as a function of the at least one unique light source identifier and the relative distance information.
US10071891B2	Systems, devices, and methods for providing passenger transport Systems, apparatuses and methods for providing passenger transport are provided. A system for providing passenger transport includes a plurality of passenger carriers, a plurality of motorized transport units each configured to mechanically couple at least one of the plurality of passenger carriers, and a central computer system communicatively coupled to the plurality of motorized transport units. The central computer system being configured to receive a ride request from a customer, instruct a motorized transport unit to travel to a passenger carrier and couple to the passenger carrier, and instruct the motorized transport unit coupled to the passenger carrier to travel to the customer to provide transportation to the customer.
US10071889B1	Piñata hoisting device A piñata hanging or holder device offers the user stability and flexibility in controlling a piñata at party events. The hanging device is collapsible for shipping and storage. The hanging device is easily assembled and utilizes the user's weight to further stabilize the device from falling or tilting. For assembly, guiding marks are providing in poles to assist the user for ease of assembly. One benefit of this device is that the device does not require anchoring or include a ballast to keep the handing device erect, which reduces shipping and manufacturing cost.
US10071874B2	Paddle control for post processing device with standby tray In accordance with an embodiment, a sheet processing apparatus comprises a standby section configured to buffer a sheet; a processing section configured to receive sheets supplied from the standby section and execute a post processing on the sheets; a rotational shaft configured to rotate around an axis of rotation; a paddle arranged in the rotational shaft and configured to contact the sheet and move the sheets by rotating with the rotational shaft, the paddle being configured to slide the sheets on the processing section to a stopper for aligning the sheets; and a controller configured to control a rotational speed of the rotational shaft to rotate the paddle at a first speed, and control the rotational speed of the rotational shaft to rotate the paddle at a second speed slower than the first speed while the paddle contacts the sheets on the processing section for aligning.
US10071871B2	Air knife configured to improve rolling of paper product Described herein are methods and systems for minimizing folding defects when rolling a paper product. The method comprises rotating a roll in a manner that draws a paper product toward the roll. The location of a pick-up point between the roll and the paper product is altered by influencing the air pressure experienced by the paper product. This may be accomplished by flowing air in one of several manners described in the specification.
US10071870B2	Methods of winding substrates having three-dimensional features The present disclosure provides methods of winding substrates comprising three-dimensional features about a core to form a spool so that at least a majority of the three-dimensional features in one wrap of a lane of the spool are at least partially nested with a majority of the three-dimensional features in another adjacent wrap in the same lane of the spool. By at least partially nesting these three-dimensional features in adjacent wraps of a lane of the spool, the three-dimensional features may be at least mostly maintained in the substrates without significant compression during winding and storage of the spool.
US10071869B2	Medium feeder and image reading apparatus A medium feeder includes a medium mounter, a pair of edge guides, and a sheet number limiter. The medium mounter has a mounting surface on which a medium to be fed is placed. The pair of edge guides is provided at the medium mounter to guide side edges of the medium in a direction that intersects with a feeding direction in which the medium is fed. The sheet number limiter is provided at the pair of edge guides to limit the number of media mountable on the medium mounter. The sheet number limiter has an extension that extends in a feeding direction of the medium such that a distance between the extension and the mounting surface increases downstream.
US10071868B2	Method for reorienting and/or stacking products A method for reorienting products includes providing one or more products in a first orientation on a surface; advancing the one or more products in the machine direction at a nominal advance rate; and retracting an end of the surface in a reverse machine direction at a nominal retract rate, such that the one or more products are advanced beyond said end into a landing region. Said end is disposed at a first elevation. The method further comprises deflecting a leading end of at least one product, such that the at least one product lands in a second orientation on a landing surface disposed in the landing region at a second elevation. The first orientation is different than the second orientation, and the first elevation is higher than the second elevation.
US10071863B2	Method for processing material for a gasifier A method for providing material to a gasifier. The method comprises providing a feedstock. A flow of the feedstock is formed. The flow is then delivered to a gasifier such that it provides a substantially airtight seal to the gasifier.
US10071858B2	Method and system for commissioning products A method for collecting products listed in an order in a product collecting system having a plurality of modules, the method including: assigning the order to a module, allocating a product listed in the order to the order if the product is already available in the module, allocating a product to the order from another module if the product of the “slow-moving” type is not already available in the module whereas it is available in the other module, allocating a product to the order from a pallet warehouse if the product of the “slow-moving” type is not already available in the module nor in another module, and releasing the order and loading the products onto a collecting carrier when all the products listed in the order have been collected in the module.
US10071857B2	Method and apparatus for sorting or retreiving items A method and apparatus are provided for sorting or retrieving items to/from a plurality of destinations areas. The items are loaded onto one of a plurality of independently controlled delivery vehicles. The delivery vehicles follow a track that guides the delivery vehicles to/from the destination areas, which are positioned along the track. Once at the appropriate destination area, an item is transferred between the delivery vehicle and the destination area.
US10071854B2	Steep-angle conveying installation for open-cast mining Steep-angle conveying installations may be used to transport raw materials along a slope of an open-cast mining pit, typically from a low-level loading station at a working level of the open-cast mining pit to a high-level unloading station at a ground level. The steep-angle conveying installation may comprise a track arranged on the slope of the open-cast mining pit, as well as one or more conveying cages for moving raw materials along the track between the various levels. Each conveying cage may include an emptying flap that is movable between an open position and a closed position. A thrust carriage may be employed outside the conveying cages to move the emptying flap of the conveying cages between the open and closed positions.
US10071853B2	Methods and systems for mass distribution of supply packs An aerial distribution system and method for deploying items is disclosed. The system includes a bulk shipping container comprised of a single piece of corrugated plastic, cut and folded into a closable box, a plurality of deployment boxes within the bulk shipping container, each deployment box containing at least one item, a plurality of tethers, each tether coupling a deployment box to the bulk shipping container, and a freefall retarding device coupled to the bulk shipping container.
US10071852B2	Beverage brewing product A beverage brewing product for brewing a sweetened beverage is disclosed which produces a sweetened beverage solution that can be mixed with a diluting liquid and which comprises at least one water permeable sieve wherein beverage material and granulated sweetener are contained. The beverage material and sweetener are brewed and dissolved during steeping in hot water to produce a sweetened beverage solution. The beverage solution, if concentrated, is then mixed with a proportioned amount of diluting liquid to make a consistently sweet beverage. This beverage brewing product may be used to produce a variety of consistently sweetened beverages, including tea, coffee, lemonade, and other sweetened beverages.
US10071851B2	Apparatus and products for producing beverages, and methods for making and using same A brewing container for use with brewing machines, the container including a distribution outlet for dispersing the injected water in at least 3 directions away from vertical within the cartridge.
US10071848B2	Smart bin lottery ticket dispenser with electronic displays A lottery ticket dispenser array includes a plurality of separate bins, with each bin defined by a housing having a defined first internal space for receipt of a supply of interconnected lottery tickets. Each bin has an electronic ticket drive mechanism and a scanner disposed to read a sequential number code as the lottery tickets are dispensed from the bin. A control system is in communication with each scanner. Each bin includes a first electronic display at a front side thereof. The control system is configured for receipt of a scan signal from the scanner and, at the end of a ticket dispense cycle, to determine the lottery ticket number of a next lottery ticket to be dispensed from the bin and to transmit the next lottery number to the first electronic display.
US10071845B2	Paper-made container and method for preparing the paper-made container A paper-made container, in which it is unlikely to feel the heat at the time of holding the container with a hand and generation of poor appearance due to excessive expansion is prevented, without increasing the thickness of an expanded insulating layer and not resulting in a corresponding deterioration of transporting efficiency, and a method for preparing the paper-made container are provided. The paper-made container of the present invention comprises a container main body consisting of a barrel portion and a bottom plate portion, and an expanded insulating layer consisting of an expanded portion and an expansion-inhibited portion, provided on the side of the outer surface of the barrel portion, in which the expanded insulating layer is formed by heating a thermoplastic resin layer having an expansion inhibiting ink-coated portion, and the ratio of the thickness of the expansion-inhibited portion to the thickness of the expanded portion is 25% or less.
US10071835B1	Stackable molded cap An injection molded plastic closure, stackable with similar closures in a known manner to prevent warping during cooling and to increase box storage capacity, is formed with a lead-in taper at the bottom of the closure skirt, maintaining and enhancing the stacking function while greatly reducing and nearly eliminating problems of cross-threading when the closure is screwed onto a container by machinery during a capping operation.
US10071828B2	System and method for packaging of nested products A packaging system for the selection, grouping and loading of varying size and/or configuration product packs into cartons as provided. The packaging system includes a selection area having a primary selector for forming an initial product pack configuration, and a secondary selector adapted to select and direct an additional grouping of products into a nested arrangement against the initial product pack so as to form a nested product pack. The nested product packs thereafter can be engaged by loader arms of a pair of opposed loading assemblies, which move the nested product packs into a series of cartons moving through the packaging machine. Thereafter, the ends of the cartons can be closed and sealed to complete the packaging of the product packs therein.
US10071826B2	Hot fill process with closures made from high density polyethylene compositions High density (density ≥0.950 g/cm3) polyethylene compositions for use in hot fill closures and processes.
US10071823B2	Extendible boom An asymmetric mast is disclosed that can be used for solar arrays. The asymmetric mast can have an asymmetry out of the plane of the solar blanket. The mast may include two or more booms that comprise slit tube longerons. In some embodiments, a single mast can be used with one or two solar blankets.
US10071822B2	Method and system for automated luggage security inspection A system and method of operating a checked bag reconciliation area of an airport. The method includes transporting a luggage item from an entrance mechanism to one of a plurality of inspection stations. Once the luggage item is at the inspection station, the method proceeds by conducting an inspection of the luggage item by the agent at the inspection station. The step of transporting the luggage item includes transporting the luggage item to the inspection station with the luggage item disposed on an automatic material handling device, and the step of conducting an inspection of the luggage item by the agent includes conducting the inspection of the luggage item while the luggage item is disposed on the automatic material handling device.
US10071818B2	Systems and methods for providing airplane performance calculations A flight management system which is capable of monitoring changes in airplane characteristics such as fuel flow and drag. When a predetermined event is triggered, the flight management system (FMS) creates or updates a set of “dynamic” tables in a database which enable FMS performance algorithms to utilize the latest fuel flow and drag data. Using the updated aerodynamic and propulsion performance data in the dynamic tables, the flight management system is able to compute more accurate flight profile and trip prediction parameters such as estimated time of arrival and predicted fuel consumption quantity.
US10071816B2	Tank wall connector system A tank wall connector system for use with a composite tank, the connector comprises a connector having a body extending from an interior of the tank to an exterior of the tank when installed through a hole in the composite tank. The connector has a first electrical conductivity property. An interface is positioned between the connector and a wall of the composite tank when installed to the tank thereby preventing physical contact between the connector and the tank wall in the interior of the tank, the interface having a second electrical conductivity property, different from the first electrical conductivity property.
US10071815B2	Thrust recovery outflow valves for use with aircraft Thrust recovery outflow valves for aircraft are disclosed. An example thrust recovery outflow valve includes a flow control member having a first aerodynamic surface and a second aerodynamic surface to define at least a portion of a fluid flow passageway between an inlet and an outlet of the thrust recovery outflow valve. A first portion of the first aerodynamic surface and a first portion of the second aerodynamic surface provides a converging profile between the inlet and a throat of the fluid flow passageway. A second portion of the first aerodynamic surface and a second portion of the second aerodynamic surface provides a diverging profile between the throat and the outlet of the fluid flow passageway. The fluid flow passageway is positioned at a small angle relative to an outer surface of an aircraft to enable fluid exiting the fluid flow passageway to provide a thrust recovery vector oriented substantially parallel to the outer surface of the aircraft and opposite a direction of drag.
US10071810B1	Methods and apparatus for a parachute retainer Movement of a disrupter cannon is arrested by a parachute. The parachute is coupled (e.g., tethered) to the disrupter cannon. Prior to firing the cannon, the parachute is held in a retainer. Movement of the disrupter cannon in response to firing pulls the parachute from the retainer. The parachute deploys and arrests the movement of the disrupter cannon. The retainer protects the parachute prior to firing the disrupter cannon. The retainer may hold the parachute during transport.
US10071809B2	System and method for reserve parachute deployment A trap system is presented for deployment of a reserve parachute. The trap system includes a trap line with a first end coupled to a main parachute and a trap attached to a surface of the container. The trap includes an outer perimeter to removably hold the trap line and an interior to removably hold the reserve bridle. A kit is also presented for converting a parachute container into an improved parachute container to deploy a reserve parachute. The kit includes an attachment to be secured to a surface of the parachute container. The attachment includes a trap line with a first end configured to be coupled to the first end of the RSL lanyard, and a trap secured to a region of the attachment, with an outer perimeter to removably hold a second end of the trap line and an interior to removably hold the reserve bridle.
US10071808B1	Aircraft icing conditions detection systems and methods An icing conditions detection system is configured to detect icing conditions with respect to an aircraft. The icing conditions detection system includes an icing conditions detector secured to a surface of the aircraft and that is configured to detect liquid water within an air stream through which the aircraft flies. A free stream of atmospheric air passes over the icing conditions detector during flight. An icing conditions determination control unit is communicatively coupled to the icing conditions detector, and is configured to detect a first icing condition and a second icing condition based on at least one icing conditions signal received from the icing conditions detector. The first icing condition differs from the second icing condition.
US10071801B2	Tri-rotor aircraft capable of vertical takeoff and landing and transitioning to forward flight Systems, methods, and devices provide a vehicle, such as an aircraft, with rotors configured to function as a tri-copter for vertical takeoff and landing (“VTOL”) and a fixed-wing vehicle for forward flight. One rotor may be mounted at a front of the vehicle fuselage on a hinged structure controlled by an actuator to tilt from horizontal to vertical positions. Two additional rotors may be mounted on the horizontal surface of the vehicle tail structure with rotor axes oriented vertically to the fuselage. For forward flight of the vehicle, the front rotor may be rotated down such that the front rotor axis may be oriented horizontally along the fuselage and the front rotor may act as a propeller. For vertical flight, the front rotor may be rotated up such that the front rotor axis may be oriented vertically to the fuselage, while the tail rotors may be activated.
US10071792B2	Underwater personal submersible An underwater personal submersible is provided. The underwater personal submersible can include a main body comprising a tripod structure of two forward-swept stabilizing surfaces and a main section including a user compartment, a plurality of oxygen tanks, and a propulsion mechanism. The placement of the propulsion mechanism and the stabilizing surfaces increases the maneuverability of the submersible.
US10071790B2	Subsea wellbore operations vessel A vessel is adapted to perform subsea wellbore related operations involving a riser string between the subsea wellbore and the vessel, e.g. drilling and/or wellbore intervention. The vessel includes a hull having a deck, and a riser storage hold present within the hull below the deck. The riser storage hold includes storage racks adapted to store therein parallel stacks of multiple riser sections and/or pre-assembled riser stands in horizontal orientation. The vessel has an elongated riser transfer opening between the deck and the roof, the riser transfer opening extending in a direction parallel to the storage racks, the riser transfer opening having a length and a width so as to allow for transfer of a single riser section or a single riser stand in horizontal orientation via the riser transfer opening out of and into the riser storage hold, wherein the risers' handling system is suitable to work at the same time with two different lengths.
US10071789B2	Bow step and seat back for inflatable boats This invention relates to a generally molded fiberglass apparatus that serves a multipurpose function for inflatable boats. The apparatus attaches to the bow of the boat and includes a forward passenger seat with a backrest and optionally servers to provide a step for embarking or disembarking the boat at the bow, and location for affixing one or more marine navigational or safety devices or accessories. The invention is affixed to the inner bow section of the passenger area to an inflatable tubular member craft by a permanent or semi-permanent means including, but not limited to clamps, adhesives, bolts, clips, snaps, ties, ratchets, or a combination thereof. The apparatus is shaped to conform to the topside bow curvature of the inflatable boat and to the adjacent concave curvature on the substantially vertical section within the passenger area at the bow of the inflatable boat, utilizing the craft's structure as the seated area.
US10071788B1	Speed control system for electric bicycles A speed control system for electric bicycles includes a bicycle having pedals, a motor and a battery which provides electric power to the motor. The bicycle includes a speed detector to detect speed of the bicycle to create a current speed value. A controller is electrically connected to the motor, the battery and the speed detector. The controller has a preset constant-speed setting value. The controller receives the current speed value from the speed detector, and compares the current speed value with the preset constant-speed setting value to adjust output of the motor and the battery. The controller changes the output of the motor and the battery according to the current speed so that the motor assists the rider to operate the bicycle instantly.
US10071785B2	Variable ride height systems and methods System, method, and assembly for controlling a vehicle. In one example, the system includes a first suspension system and a first controller. The first controller is configured to receive an input signal representing vehicle operating parameters. The first controller is also configured to receive a first target displacement determined by a second controller for a second suspension system of the vehicle. The first controller is further configured to determine a second target displacement for the first suspension system of the vehicle based on the first target displacement and the input signal. The first controller is also configured to set a height of the first suspension system based on the second target displacement.
US10071780B1	Stabilized two-wheeled trailer A narrow gauge two-wheeled trailer mounted on spaced apart elongated beams and split axles is stabilized against rolling or tilting about the longitudinal axis with a leaf spring suspension and a universal joint coupling. The split axles are mounted on an axle arms pivoted to the beams and supported by leaf springs configured to lengthen or shorten along the beams. The universal joint coupling permits pitch and yaw movement of the trailer but resists rolling.
US10071778B2	Torque stick apparatus and methods of use A method of operating a personal transporter includes mounting the personal transporter. A torque stick apparatus having a rotating wheel is provided. The wheel of the torque stick apparatus is positioned against a drive surface to drive the personal transporter across a transport surface.
US10071776B2	Wake convergence device for a vehicle A wake convergence device for a vehicle is provided, wherein the vehicle has a vehicle top and first and second vehicle sides each extending from the vehicle top. The vehicle includes a vehicle leading edge, a vehicle trailing edge, and a vehicle longitudinal axis. The wake convergence device includes a first side panel positioned beside and spaced from the first vehicle side and including a first side panel leading edge that transitions from forward of the vehicle trailing edge to aft of the vehicle trailing edge. The wake convergence device also includes a second side panel positioned beside and spaced from the second vehicle side and including a first side panel leading edge that transitions from forward of the vehicle trailing edge to aft of the vehicle trailing edge.
US10071775B1	Cargo bed side top extender A covering for a wall of a vehicle cargo bed includes a first portion structured to be attached to a top portion of the wall, and a second portion rotatably connected to the first portion. The first portion has a first surface, and the second portion has a first surface. The second portion is rotatable between a first orientation in which the second portion first surface resides directly opposite the first portion first surface and faces in a first direction toward the first portion first surface, and a second orientation in which the second portion first surface faces in a second direction opposite the first direction. A shoulder extends from an edge of the second portion at an angle with respect to the second portion first surface.
US10071773B2	Vehicle roof structures for concealing one or more sensors A vehicle roof structure for concealing one or more sensors therein includes a roof panel, a windshield extending up to the roof panel, and a spoiler. The spoiler extends across at least a portion of a width of the roof panel and includes a leading portion that is substantially parallel to a windshield-roof interface, an apex, wherein a height of the spoiler increases from a height of the roof panel to a height of the apex as the spoiler extends from the leading portion to the apex in a vehicle longitudinal direction, and a trailing portion extending from the apex to the roof panel. A sensor volume is formed between the spoiler and the roof panel. One or more sensors are at least partially positioned within the sensor volume, wherein the one or more sensors output a signal indicative of a characteristic of an environment of the vehicle.
US10071772B2	Power unit mounting structure A power unit mounting structure of a vehicle includes a power unit 100, a sub frame 200 disposed below the power unit 100 in the vehicle height direction and at least one attaching bracket 220 for attaching the power unit 100 on the sub frame 200, the power unit 100 has an arm 210 extended from the main body portion thereof to the attaching bracket 220, a tip portion of the arm 210 is axially supported on a pair of shaft supporting portions 221 of the attaching bracket 220 with a shaft member 213 extended to the width direction of the vehicle, and the shaft supporting portion 221 of the attaching bracket 220 has fragile portions 222, 223 which break when the impact is applied such that the aria 210 of the power unit 100 shifts to the front direction.
US10071769B2	Front vehicle body reinforcing structure A front vehicle body reinforcing structure may include a dash panel, a front side member extending along a length direction of a vehicle for coupling to a lower part of the dash panel, a fender apron member extending along the length direction of the vehicle and coupled to an upper part of the dash panel, a front shock absorber housing having a lower part coupled to the front side member and an upper part coupled to the fender apron member, a cowl cross member extending along a width direction of the vehicle for coupling to the upper part of the dash panel and having both ends overlapping and coupled to the front shock absorber housing along the width direction, and a front shock absorber housing side member adhered to an inner surface of the front shock absorber housing, and having an upper part coupled to the cowl cross member.
US10071767B2	Floor structure of a motor vehicle A floor structure (1) of a motor vehicle has a vehicle floor (2). A central tunnel (3) extends in a longitudinal direction of the motor vehicle and is connected to the vehicle floor (2). Two seat crossmembers (4a, 4b) are spaced apart from one another in a transverse direction of the motor vehicle and the central tunnel (3) extends between the seat crossmembers (4a, 4b) in sections. The floor structure (1) has regions of attachment to the central tunnel (3) on both sides of the central tunnel (3) and cast bridges (5a, 5b) are inserted into the floor structure (1) in the regions of attachment to the central tunnel (3).
US10071765B2	Vehicle pedal arm A vehicle pedal arm has a first rib connecting a first hole, into which a first shaft is inserted, and a peripheral edge on a side of a rear wall continuous of at least one of a left side wall and a right side wall in an arm body continuous upward from a first bent portion that bends in a rear direction side of a vehicle as being a lower side of the vehicle, to extend on a first straight line connecting a depressing portion and the first hole in a side view, and a second rib connecting a second hole, into which a second shaft is inserted, and the peripheral edge on a side of the rear wall continuous of the at least one of the both side walls to extend on a second straight line connecting the depressing portion and the second hole in a side view.
US10071764B2	Methods to control a steering system An embodiment of a system for evaluating a torque sensor includes an input module configured to receive torque signals from a hand wheel torque sensor in a vehicle, and a sensor evaluation module configured to perform monitoring a condition affecting the hand wheel torque sensor, and determining whether the condition indicates a desired situation in which a probability of an input torque being applied to the hand wheel is below a selected threshold. The sensor evaluation module is also configured to perform, based on detecting the desired situation, automatically analyzing the torque signals received during a time duration of the desired situation to estimate one or more torque sensor error values, and outputting at least one of a corrected torque signal and the one or more error values to a torque command generation module, the torque command generation module configured to generate a torque command to an electric motor.
US10071762B2	Detection and mitigation of inverter errors in steering system motors Technical solutions are described for detecting an error in an inverter associated with a motor of a power steering system and operating the power steering system in response to the error. An example system includes a transistor pair that selectively provides power to a corresponding phase coil of the motor. The system further includes a detection module that detects a resistance error in the transistor pair by monitoring a voltage across a shunt resistor of the transistor pair in response to a gate drive command applied to the transistor pair. The system further includes a mitigation module that selects a mode of operation of the inverter based on the resistance error. The system also includes a motor control module that controls the inverter according to the mode of operation.
US10071759B2	Shopping cart basket and method of manufacture A shopping cart in one embodiment comprises a uniframe, a mat basket, and a slim-fit cart frame and basket combination, as well as in multiple embodiments, providing individual structural differences and advantages over pre-existing forms of shopping carts.
US10071755B2	Housing device for a magnet body for an electromagnetic or permanently magnetic rail brake for a rail vehicle and electromagnetic or permanently magnetic rail brake for a rail vehicle The disclosed embodiments relate to a housing device for a magnet body for an electromagnetic rail brake for a rail vehicle. The housing device has a first cable feed-through opening for the feeding through of a first electrical connection cable into the magnet body. The housing device is characterized in that a first axial-extent axis of the first cable feed-through opening is arranged at an acute inclination angle to a main surface of the housing device adjacent to the first cable feed-through opening, wherein the first cable feed-through opening is arranged in the center of the rail brake within a tolerance range.
US10071754B2	Railcar with buffer A railcar according to the present disclosure includes a buffer installed in an end portion of each of coupled cars, and urging each other in a car longitudinal direction, the buffer having a stem movable in the car longitudinal direction and a spring urging the stem, an underframe internally enclosing part of the buffer and including an opening on a top plate of the underframe, and a compression mechanism forcibly compressing the spring to move the stem, part of the compression mechanism being freely brought into and out of the opening.
US10071752B2	Movable footboard for a vehicle door A movable footboard for a door of a rail vehicle comprises a footboard extendable below a tread strip at least substantially transversely to the direction of travel. To minimize the level difference between the footboard and the tread strip a pivot shaft extends at least substantially parallel to the direction of travel on at least one longitudinal bar of the footboard at the end region of the footboard away from the vehicle, about which pivot shaft at least two pivoting bars are pivotably supported, which pivoting bars each bear a transverse profile element, each of the pivoting bars being rigidly connected to the transverse profile element associated with the pivot bar, while the other transverse profile elements lie freely on said pivot bar, and a lifting mechanism is fastened to the vehicle and lifts the transverse profile element located directly in front of the tread strip.
US10071749B2	External runflat apparatus An external runflat apparatus for a guide wheel system of a monorail transport system. The external runflat apparatus includes a hub member and a tread member. The tread member is connected to the hub member and includes a base member and a covering over the base member.
US10071748B2	System and method for providing driving assistance to safely overtake a vehicle Various aspects of a system and method to provide driving assistance to safely overtake a vehicle are disclosed herein. In accordance with an embodiment, an electronic control unit used in a first vehicle is configured to detect a second vehicle in front of the first vehicle. A first position associated with the first vehicle and a second position associated with the detected second vehicle is determined for a first time instance. It may be determined whether a lateral distance between the determined first position and the determined second position is below a pre-defined threshold distance. A first alert is generated when the determined lateral distance is below the pre-defined threshold distance.
US10071746B2	Methods and apparatus to alter a vehicle operation Methods and apparatus are disclosed to alter the driving profile of a vehicle. An example method disclosed herein determines, based on a user selection, a desired driving profile to apply to a vehicle. The example method includes identifying a set of alterations to operating parameters of vehicle systems associated with the desired driving profile. The example method includes determining a subset of the set of alterations that the vehicle can execute, and in response to determining the subset that the vehicle can execute, applying the subset to the vehicle to produce the desired driving profile.
US10071741B2	Driver assistance apparatus for vehicle and vehicle having the same A driver assistance apparatus includes an object detection sensor configured to acquire data in a driving direction of a vehicle or around the vehicle. The driver assistance apparatus also includes a processor that is configured to detect an object based on the acquired data and determine, based on the acquired data, a portion of the detected object that is expected to be impacted by the vehicle. The processor is also configured to provide, based on the determined portion of the detected object that is expected to be impacted by the vehicle, a height control signal that controls a suspension of the vehicle to adjust a height of at least a portion of the vehicle.
US10071740B2	Vehicle control apparatus, and method of controlling same A vehicle control apparatus includes: a first target driving force calculation unit that calculates a first target driving force based on an accelerator pedal opening; a target speed ratio calculation unit that calculates a target speed ratio of a continuously variable transmission based on the first target driving force; a target torque calculation unit that calculates a target torque of a driving source based on the first target driving force; an air density detection unit that detects air density; and a first correction unit that corrects only the target torque, out of the target speed ratio and the target torque, in accordance with the air density.
US10071735B2	Airspeed adaptive cruise control for ground vehicles A system and method for implementing an airspeed adaptive cruise control system on ground vehicles that automatically slows vehicle groundspeed during headwinds and increases groundspeed during tailwinds. This behavior acts to reduce the energy cost associated with headwinds and capture the energy benefit obtained with tailwinds. In the method, multiple operating modes are presented that can be user selected to optimize on minimum energy consumption, fastest average speed while still harvesting energy from tailwinds, and a balance in between the two methods. The system utilizes multiple sensors, such as airspeed, groundspeed, and vehicle proximity detectors to provide reliable system functionality in a wide range of operating conditions. In some implementations, a combined speedometer with groundspeed and airspeed indicator dials is used to quickly communicate the condition and magnitude of headwinds or tailwinds.
US10071731B2	Parking assist apparatus In a case where an actual parking technique of a driver in a parking condition is different from a parking technique shown by a parking technique model generated in a same parking condition, a parking assist apparatus outputs a question to the user about whether or not assistance for the parking operation is desired to park the vehicle. In a case where the driver accepts the assistance for the parking operation, the parking assist apparatus provide the assistance for the parking operation to park the vehicle. Thus, useless parking assistance that the driver does not desire can be prevented, and parking assistance that is truly desired by the driver can be executed.
US10071730B2	Vehicle parking control Methods and Systems are provided for performing an automated parking operation of a vehicle. The methods and systems determine a position of a wireless driver device located outside of the vehicle. A vision system provides video data having a field of view selected based on the position of the wireless driver device. Gesture recognition processing is performed on the video data having the selected field of view. At least one gesture command is determined from the gesture recognition processing. An automated parking operation of the vehicle is performed using the at least one gesture command.
US10071729B2	Tow damping system A vehicle includes a trailer hitch, an axle having an electronic limited slip differential, and a controller. The electronic limited slip differential includes a variable torque capacity lockup clutch. The controller is programmed to, in response to detecting the presence of a trailer connected to the trailer hitch and an increase in vehicle speed, increase the lockup clutch torque by a first torque adjustment.
US10071728B2	Method for controlling a hybrid vehicle driveline A method is provided to control a hybrid powertrain, comprising a combustion engine; a gearbox with input and output shafts, which combustion engine is connected to the input shaft; a first planetary gear connected to the input shaft; a second planetary gear connected to the first planetary gear; first and second electrical machines respectfully connected to the first and second planetary gears; first gear pair connected with the first planetary gear and output shaft; and second gear pair connected with the second planetary gear and output shaft. The method comprises: a) engaging gears in the first and second gear pairs; and b) connecting two rotatable components in the second planetary gear with a second coupling device.
US10071726B2	Shifting control method for hybrid vehicles A shifting control method for hybrid vehicles may include shifting request determining, by a controller, of determining whether power off down shifting to a lowest stage is requested, clutch releasing, by the controller, of controlling a release clutch to be released, when it is determined that a gradient of a road exceeds a reference value and a vehicle speed exceeds a reference vehicle speed when the shifting is requested as the shifting request determination result, synchronizing, by the controller, of controlling a motor speed to be synchronized with an applying input shaft speed, and clutch engaging, by the controller, of controlling an applying clutch to be engaged.
US10071724B2	Regenerative torque limit control A vehicle includes a powertrain and at least one controller programmed to, in response to a brake request and a shaft speed associated with a speed of the vehicle achieving a starting speed that is defined by a torque of the powertrain that changes with brake demand at a given shaft speed, reduce a regenerative torque limit that constrains regenerative braking torque over a blend-out duration based on the shaft speed.
US10071718B2	Setting device, particularly a motor vehicle parking brake A setting device, particularly a motor vehicle parking brake includes a remotely-operated drive, a hollow shaft, a spindle shaft and an elastic element. The hollow shaft is driven by the remotely-operated drive so that the hollow shaft rotates. The spindle shaft moves relative to the hollow shaft within the hollow shaft due to the rotation of the hollow shaft. The spindle shaft is connected to a brake cable such that the spindle shaft can apply and release the brake as it moves in different directions within the hollow shaft. The elastic element is loaded due to movement of the hollow shaft as the hollow shaft is driven in an attempt to release the brake while the brake cable is blocked.
US10071713B2	Plastic heat-conducting component for a system for supplying and/or distributing a window-washing liquid for a motor vehicle The invention relates to a component (10) for a system (9) for supplying and/or distributing a liquid for a wiping apparatus for a motor vehicle, including a space, defined by a wall, in which the liquid can be accommodated, characterized in that the wall is made of a plastic heat-conducting material. The invention can be used for motor vehicles.
US10071709B2	Electropneumatic windshield wiper drive for a rail vehicle, drive for a windshield wiper and pneumatic system for operating a drive for a windshield wiper A pneumatic system for operating a drive for a windshield wiper for a rail vehicle, wherein the windshield wiper drive has a piston guide device that has a first connection and a second connection opposite the first connection. At least one piston in the piston guide device carries out linear movements in opposite directions along the main direction of extension of the piston guide device to bring about an alternating rotational movement of the wiper shaft. The pneumatic system has a supply connection for a compressed air supply, wherein the supply connection is connected to the first connection via a first normal operation connection line and a first emergency operation connection line arranged parallel thereto and to the second connection via a second normal operation connection line and a second emergency operation connection line arranged parallel thereto.
US10071705B2	Seat belt assist device, and vehicular seat Provided are a seat belt assist device and a vehicular seat such that a seat belt can be moved to a position easily accessible by a seated person in a compact and simple configuration. A seat belt assist device is configured to move at least a part of a seat belt of a seat for a vehicle to a position easily accessible by a seated person, and is provided with a movable member that supports a part of the seat belt and that moves between a normal position and a protruded position that protrudes beyond the normal position. The movable member is disposed on an upper surface of a seat back of the seat, with an end portion thereof at the door side of the vehicle being disposed toward an end of the upper surface of the seat back in a right and left direction, and with a forward end disposed rearward of a front end surface of the upper surface of the seat back.
US10071704B2	Apparatus and method for folding driver airbag Provided are an apparatus and a method for folding a driver airbag which are capable of folding an airbag so that the airbag has a shape corresponding to a shape of an accommodating space in an airbag housing. To this end, an upper plate of the apparatus for folding the driver airbag according to the exemplary embodiment of the present invention includes a plurality of stair sections that is spaced apart from a lower plate at different vertical distances.
US10071702B2	Vehicle occupant protection device A vehicle occupant protection device includes: an airbag that is configured to be stowed in a headrest, to receive a gas supply and is formed as a single bag body that, in an inflated and expanded state, includes a front inflation portion configured to be disposed at the front in a seat front-rear direction relative to a head of a vehicle occupant, and a pair of side inflation portions configured to be disposed at both sides in a seat width direction relative to the head of the vehicle occupant; an inflator that is fixed to an upper portion of a seatback frame in an attitude with a long dimension of the inflator in the seat width direction, the upper portion of the seatback frame extending in the seat width direction; and a fluid communication structure that communicates between the inflator and the airbag to allow a flow of gas.
US10071700B1	Rear impact guard for a vehicle A vehicle includes a frame and a bumper pivotally connected to the frame. A step is attached to the bumper so that the step is pivotal between a storage position and a step position. An actuator is mounted to the frame and coupled to the bumper, and is operable to pivot the bumper relative to the frame between a substantially vertical position and an angled position.
US10071699B2	Vehicle A vehicle includes a power control unit having at least one of an inverter and a converter, a drive motor that produces torque for running the vehicle when electric power is supplied from the power control unit to the drive motor, a vehicle body kept insulated from a road surface, a case main body in which the power control unit is housed, a member that is connected to the case main body where the member is insulated from the case main body, or in a condition in which electric resistance is large, and a static eliminator that neutralizes and eliminates positive charges on the member and lowers a positive potential of the member, by self-discharge for producing negative air ions in outside air according to the positive potential of the member that is electrostatically charged.
US10071694B2	Carrier apparatus for vehicle A carrier apparatus for a vehicle is disposed on a bumper back beam in the rear part of a vehicle. The carrier apparatus normally is not exposed externally, and is withdrawn from the bumper back beam such that a bicycle can be loaded thereon when the bicycle is required to be loaded. It is thereby possible to preserve a vehicle's aesthetic exterior appearance and improve convenience. When the carrier is withdrawn, the license plate and the fixing bar rotate in concert with each other. When the carrier is retracted, the fixing bar and the license plate are folded together. Consequently, convenience is further increased, thereby improving the marketability of the carrier apparatus.
US10071692B2	Pickup truck roof rack system The present disclosure relates to an article carrier system particularly adapted for use with a pickup truck. The system employs a first pair of support tracks secured to a roof surface of a pickup truck, and a rear spoiler portion coupled to each of the first support tracks and extending therebetween adjacent a rear area of the roof surface. A second pair of support tracks is secured to a pair of truck bed sidewalls. A combination spoiler/support subsystem is supported from the second pair of support tracks and is adjustably positionable to provide a variable spacing between the rear spoiler portion and the spoiler/support subsystem, to thus tailor the system to support articles of various lengths thereon. The rear spoiler portion and the spoiler/support subsystem provide an appearance of a single, integrated spoiler when positioned closely adjacent one another.
US10071690B2	Expandable top for vehicle center console A vehicle center console includes an expandable top disposed on a storage bin. The center console is slidably connected to a floor pan and is movable towards the second-row seats. The expandable top includes a central component having an upper side and an underside, and a telescoping mechanism attached to first and second movable side components. The telescoping mechanism includes a body connected to the underside and a pair of telescoping arms extending from opposing sides of the body and movable between at least an extended position and a collapsed position. Each of the side components are attached to one of the arms such that undersides of the side components overlap the upper side of the central component when the arms are in the collapsed position, and the upper side of the central component is substantially flush with upper sides of the side components when the arms are in the extended position.
US10071687B2	Vision system for vehicle A vision system for a vehicle includes multiple cameras disposed at a vehicle each having a field of view exterior of the vehicle. A display device is operable to display, for viewing by a driver of the vehicle, at least one of (a) video images captured by at least some of the cameras and (b) a composite image formed from image data captured by at least some of the cameras. The image data captured by at least some of the cameras is sent to a central video/image processor and the sent image data is substantially unmodified and is as captured by the respective ones of the camera or cameras. At least one of the cameras may have a tunable lens. The camera may provide almost raw image data to the display device and a graphic engine may run as a routine at the display device.
US10071684B2	Light guide assembly A vehicle display assembly includes a light source and a flexible light guide configured to emit light therefrom. The assembly may include a steering wheel assembly to which the flexible light guide is operably coupled. The vehicle display assembly may be configured to emit light in at least first, second, and third colors. For example, the vehicle display assembly may be configured to illuminate the flexible light guide in the first color in a first mode, in the second color in a second mode, and in the third color in a third mode.
US10071680B2	Evacuation travelling control device and evacuation travelling control method An evacuation travelling control device has an evacuation direction judgment section for detecting an evacuation direction of an own vehicle during an evacuation travelling mode of the own vehicle and a light switching pattern generation section for generating a light pattern which relates to one or more combinations of lit and unlit states of lamps including direction indicators mounted on the own vehicle when informing the evacuation direction of the own vehicle detected by the evacuation direction judgment section to drivers of other vehicles and pedestrians around the own vehicle.
US10071678B2	Aerial lift and method for implementing same Disclosed is an aerial lift, including: a lower portion with members for ground connection; a lifting structure; a platform supported by the lifting structure; and a lighting system. The aerial lift includes a control console on the platform, whose position is variable relative to the ground connection members. The lighting devices are arranged on the lower portion of the aerial lift and/or on the lifting structure or the platform and selectively generate light beams directed towards the ground and the immediate environment of the aerial lift, including at least partially an area beyond the edge of the members for connecting to the ground. The light beams are directed towards four sides, consisting of two opposing pairs of sides, of the aerial lift regardless of the position of the control console relative to the members for connecting to the ground. Also disclosed is a method for implementing such an aerial lift.
US10071675B2	Autonomous vehicle headlight deactivation A vehicle system includes an autonomous driving sensor and a processor. The autonomous driving sensor is programmed to output an object detection signal representing an object near a host vehicle. The processor is programmed to output a headlight activation signal to activate vehicle headlights in response to receiving the object detection signal and while the host vehicle is operating in an autonomous mode.
US10071672B2	Method and circuit arrangement for feeding a series circuit of n LED units A method and a circuit arrangement for feeding n LED units (LED1 to LED5) of a lighting unit of a motor vehicle by way of a controlled power source (5) from a voltage source (2) having a fluctuating operating voltage (UB), in which the LED units (LED1 to LED5) are interconnected, and in particular k LED units (LED1 to LED5) of a series connection are short-circuited, when the operating voltage (UB) drops, taking a stored weighting with respect to the priority assigned to individual LED units into consideration, wherein current continues to flow simultaneously through (n−k) LED units. A memory unit (7) for storing information about weightings on the priority of certain LED units is assigned to the control unit (3) for activating the power source, a switching matrix (4′, S1 to S4), and in particular a circuit arrangement composed of n controlled switches (S1 to S4) that each bypass the LED units (LED1 to LED4, LED5) is provided, and the control unit (3) is configured to compared the operating voltage and/or the current (IS) of the power source to predefinable threshold values and to interconnect the LED units as a function of this comparison and the weighting.
US10071669B2	Grain cart with auger delivery on either side An agricultural wagon for moving particulate material from within the wagon to a separate storage vessel is provided. The wagon includes a bin defined by walls. The wagon may also include one or two augers, such as a floor and lift auger for moving the material from within the bin to the storage vessel. The lift auger is movable relative to the storage bin such that it can dispense the material via a hood from either the left or right sides of the bin, such as at either the left or right and front corners of the bin. A mechanism including actuators and a guide can aid in moving the auger to the desired side for dispensing. The lift auger can further be folded in front of the bin when in a transport configuration, such as traveling on a road.
US10071668B2	Vehicle mounted loading and unloading apparatus A vehicle mounted loading and unloading apparatus is provided which has a stationary mounting rack removably attachable to a roof of a vehicle and a top rack that includes a container for storing cargo, such as bales of hay. An adjustment mechanism is provided to move the top rack relative to the mounting rack from a transporting position to a loading/unloading position in which the top rack is lowered behind the vehicle to facilitate loading cargo. A movable shelf may be provided on the top rack for assisting with loading and unloading cargo. The shelf is slidable between a rear end of the top rack and a front end of the top rack for placing the cargo.
US10071667B2	Winch system and method A winch system and method includes a mount plate with a length and a width where the length of the mount plate includes a top, front and back and where the width of the mount plate is generally uniform and smaller at opposite ends and wider in between the opposite ends such that a support platform is provided and where the front and back of the length are conformed to fit over and attach with a bed rail in a vehicle. A winch assembly is connected with the mount plate at the support platform. A power source is connected with the winch assembly and a controller is connected with the winch assembly and the power source such that power to the winch assembly is controlled by operation of the controller.
US10071666B2	Adjustable footrest An adjustable footrest for an occupant of a vehicle is presented herein. The footrest includes a footpad, footplate, and width adjustment element. The footpad extends from the foot well of the vehicle and is configured for engagement by a foot. The footplate is movably mounted to the footpad. The width adjustment element is configured to enable regulated adjustment of the footplate along the width of the footpad. The adjustable footrest may further include a support trackway configured to define telescopic adjustment of the footplate along the width of the footpad. The footpad may include a pivotable side flap and the footplate may include a flange configured to operatively connect with the side flap. The side flap can pivot towards and away from the footpad body as the footplate is adjusted along the width of the footpad.
US10071662B2	Hinge unit of console armrest for vehicle Disclosed herein is a hinge unit of a console armrest for a vehicle, which includes an upper bracket including an armrest installation part coupled to an armrest, and upper hinge parts formed at both sides of the armrest installation part, each having a first upper hinge hole, a lower bracket including a console installation part coupled to a console, and lower hinge parts formed at both sides of the console installation part, each having a first lower hinge hole, an upper bracket cover configured to surround at least a portion of each of the upper hinge parts and to have a second upper hinge hole formed at a position corresponding to the first upper hinge hole, and a lower bracket cover configured to surround at least a portion of each of the lower hinge parts and to have a second lower hinge hole.
US10071659B2	Vehicle seat and method for stowing a seat element The present invention relates to a vehicle seat (1), comprising a seat element (2), which can be height-adjusted from a usage position to a stowing position, and comprising a backrest element (3), wherein the backrest element (3) can be pivoted about a stationary primary axis (A), wherein the backrest element (3) is operatively connected to the seat element (2) by means of an articulated system in such a way that the seat element (2) can be transferred from the usage position to the stowing position by means of a pivoting motion of the backrest element (3), wherein the articulated system has a deflecting element (7), wherein the deflecting element (7) can be pivoted about a stationary secondary axis (B), wherein a secondary plane (B′), which extends perpendicularly to the direction of travel (D) and comprises the secondary axis (B), is arranged in front of a primary plane (A′), which extends perpendicularly to the direction of travel (D) and comprises the primary axis (A), in a direction extending parallel to the direction of travel (D).
US10071657B2	Double fitting for a vehicle seat, and vehicle seat A vehicle seat double fitting (10) includes two fittings (100) operatively connected to each other and each with a first fitting part (111) and a second fitting part (112) that are rotatable relative to one another around an axis (A) and are in geared connection or locked to one another. An adapter part (150) is connected to one of the first fitting parts (111) or the second fitting parts (112) and a second adapter part (160) is connected to other of the first fitting parts (111) or the second fitting parts (111, 112). Exactly one adapter part (150, 160) is fixedly connected to a structural part (3) of the vehicle seat and the other of the two adapter parts (150, 160) is limitedly moveable or rotatable around the axis (A), relative to the structural part (3) and the adapter part (150, 160) fixedly connectable to the structural part (3).
US10071651B2	Torque control apparatus and method for drive motor A torque control method for a drive motor includes detecting, by a controller, an amount an accelerator pedal is pressed. The method also includes calculating a rate of change of the accelerator pedal based on the detected amount the accelerator pedal is pressed. Further, the method also includes determining a time constant of a drive motor corresponding to the calculated rate of change.
US10071649B2	Method for controlling external electric power supply system of fuel cell-mounted vehicle, and external electric power supply system A method for controlling an external electric power supply system supplying electric power from a fuel cell and a secondary battery mounted on a vehicle to an external load, the method including controlling electric power from the fuel cell and the secondary battery such that externally supplied electric power supplied to the external load is equal to or less than supply allowed electric power, and setting the supply allowed electric power to be equal to or less than a smaller one of an upper limit value of electric power which the secondary battery is charged with set in accordance with a temperature, and an electric power storage amount of the secondary battery and an upper limit value of electric power discharged from the secondary battery set in accordance with the temperature and the electric power storage amount of the secondary battery.
US10071638B2	Electric vehicle and equipment therefor Disclosed herein is an electric vehicle including a power source, an electric motor adapted to be supplied with electric power from the power source for vehicle driving, a sheet-shaped solar battery for electric power generation, a storing portion for storing the sheet-shaped solar battery in its nonoperating condition, and a connecting unit for allowing the supply of electric power from the sheet-shaped solar battery to at least one of the electric motor and the power source, wherein when the sheet-shaped solar battery is used to perform electric power generation, the sheet-shaped solar battery is taken out of the storing portion and then spread to effect photovoltaic power generation.
US10071632B2	Electrical system for a vehicle with start/stop An electrical system for a vehicle having an internal combustion engine provided with a start/stop system includes a primary battery connectible to an engine starter motor, an alternator and an electrical load in parallel with one another and selectively connectible in parallel with the primary battery via a first switch, and a third source of electrical energy selectively connectible in parallel with the alternator via a second switch. A DC/DC converter may be arranged in parallel with the alternator for selectively charging the third source of electrical energy via the second switch. A secondary battery may be arranged in parallel with the alternator.
US10071631B1	Automatic two-wheeled vehicle display device An automatic two-wheeled vehicle display device is such that, while warning information is being displayed in a second display region, a CPU changes a background color gradation of the second display region to a first gradation (for example, white) for a first setting period t1, gradually increases backlight luminosity to reach a maximum value (100%) in a third setting period t3 that is shorter than the first setting period t1, and maintains the backlight luminosity at the maximum value (t1=t3+t4) for a fourth setting period t4. Subsequently, the CPU changes the background color gradation of the second display region to a second gradation (for example, black) for a second setting period t2, and adjusts the backlight luminosity to a luminosity the same as that in a normal mode (for example, 20%).
US10071629B2	Prime mover control device of work vehicle A prime mover control device of a work vehicle equipped with a torque converter includes: a speed ratio calculation unit that calculates a speed ratio of the torque converter; and a rotational speed limit unit that, when a speed ratio falls within a preset speed ratio range, limits a maximum rotational speed of the prime mover to be lower as compared with a maximum rotational speed set when a speed ratio falls without the preset speed ratio range. When a state in which the speed ratio calculated by the speed ratio calculation unit falls within the preset speed ratio range is maintained for a predetermined time period, the rotational speed limit unit changes a maximum rotational speed of the prime mover to a higher maximum rotational speed than the limited maximum rotational speed limited to be lower by the rotational speed limit unit.
US10071624B2	Drive device for a motor vehicle A drive device for a motor vehicle includes a primary powertrain and a secondary powertrain, wherein the primary powertrain includes a combustion engine for generating a total torque; a torque distribution device coupled to the combustion engine and including a first and a second output, wherein the torque distribution device is designed to provide a first partial torque in mechanical form at its first output derived from the total torque, and to provide a second partial torque in electrical form at its second output derived from the total torque; and a transmission which is coupled to the first output of the torque distribution device; wherein the secondary powertrain includes an electric machine which is coupled to the second output of the torque distribution device; wherein the torque distribution device includes a torque limiting device which is designed to limit the first partial torque to a presettable threshold value.
US10071617B1	Vehicle roof shade A vehicle includes a first roller having a first roller magnet and a second roller having a second roller magnet. A shade includes a first shade magnet and a second shade magnet. At least one of the first and second shade magnets are coupled to at least one of the first and second roller magnets.
US10071615B2	Air vent assembly An air vent assembly, for example, for a motor vehicle, having an air vent, which has at least one air guide louver with a trailing edge and a leading edge, whereby the air guide louver with its leading edge is mounted pivotable about a rotation axis associated with the trailing edge, and having a decorative device. It is provided that the decorative device has at least one stationary decorative louver with a visible edge extending in the extension of the trailing edge, and that the air guide louver is mounted on the decorative louver pivotable about the rotation axis.
US10071611B2	Air conditioner for vehicle An air conditioner for a vehicle includes a heating line having a condenser at an inlet thereof and having an outlet communicating with an interior of the vehicle. A cooling line has an inlet communicating with the inlet of the heating line, an outlet communicating with the interior of the vehicle, and an evaporator connected to the condenser inside of the cooling line. One or more doors are provided to control a flow stream of each line and to control a temperature of air introduced into the interior of the vehicle.
US10071607B2	Apparatus and method for mounting and removing tyres on and from respective wheel rims An apparatus for mounting and removing a tyre on and from a respective rim comprises: an element for moving a bead of the tyre in order to insert/remove the bead into/from a respective groove in the rim, the element comprising a tool connected to a respective supporting arm for moving the bead; a rotatable support for the rim, in such manner as to turn the rim and the tyre about a corresponding longitudinal axis of the rim; at least one sensor associated with the supporting arm for measuring the mechanical strain applied to the bead of the tyre when the latter is mounted on, and removed from, the rim.
US10071602B2	Heavy duty pneumatic tire A tread pattern is provided with: shoulder lug grooves open at ground contact edges; center lug grooves having two ends; circumferential primary grooves formed in a wave-like shape by alternately connecting ends of the center lug grooves and the inner ends in the tire width direction of the shoulder lug grooves; and center blocks defined by the center lug grooves and the pair of circumferential primary grooves. The belt portion of the tire includes first cross belt layers and second cross belt layers. The ratio of the width WB of the center blocks in the tire width direction to the belt width W1 of the belt layer having the shortest width in the tire width direction among the first cross belt layers is in the range from 0.6 to 0.9.
US10071600B2	Tire for motorbike A tire for a motorbike can improve turning performance and dry grip performance with good balance. In a tire for a motorbike, a tread part is provided with a first inclined groove and a second inclined groove disposed closer to a tread end than is the first inclined groove. The first inclined groove is provided to a forward-movement grounded area. An inner end of the second inclined groove is provided in an area within a range 2% of a tread expansion radius centered about an end edge of the forward-movement grounded area. An outer end of the second inclined groove is provided to a position displaced from the inner end of the second inclined groove toward the tread end by an interval 20%-30% of the tread expansion radius. Either no other grooves besides the second inclined groove are provided to a second inclined groove formation area, or the length of the area in the direction of expansion width where another groove is located in the second inclined groove formation area is 25% or less of the expansion width of the second inclined groove formation area.
US10071595B2	Vehicle with airflow control device A vehicle airflow control device includes: a wheel shutter that is provided to a vehicle wheel, and is movable by a driving mechanism between an open position at which an opening between spokes of the vehicle wheel is brought into an open state and a closed position at which the opening is brought into a closed state; a shutter device that is provided to an introduction path of an air into an engine compartment, and is switchable between an open state in which an air is permitted to be introduced and a closed state in which an introduction of an air is blocked; and a control mechanism that actuates the driving mechanism to move the wheel shutter to either one of the open position and the closed position in accordance with the open and closed states of the shutter device.
US10071594B2	Chalk line device A chalk line device that includes a housing, a reel mounted for rotation within the housing, a liquid container disposed within the housing, and a handle connected with the reel and extending outside the housing is provided. The reel is constructed and arranged to carry a chalk line wound thereon. The reel is positioned in the liquid container such that the chalk line wound therein is at least partially submerged in the liquid chalk received in the liquid container. The liquid container has a sealed configuration and an unsealed configuration. In the unsealed configuration, the liquid container is configured to receive liquid chalk therein. In the sealed configuration, the liquid container substantially seals the liquid chalk received therein. The handle is operable to wind up the chalk line onto the reel.
US10071590B2	Greeting card having audio recording capabilities with trial mode feature A greeting card having an audio message recording and playback device permits recording of personalized audio messages to be played upon opening of the greeting card. The recording device is operable in either a trial mode or a use mode. In the trial mode, which would be applicable when the card is displayed in a store, a potential purchaser may experience the functionality of the card by recording their own test message. The test message is played back initially for the potential purchaser but is not subsequently played back to be later heard by other potential purchasers. In the use mode, which the card may be switched to after purchase by removal of a trial mode panel from the greeting card, a user recorded message is played repeatedly upon subsequent openings of the card. The user recorded message may be followed by a prerecorded recording, such as a song. Additional prerecorded messages, such as voice prompts with instructions for recording a message, may also be included.
US10071589B2	Saddle stitch books and methods of producing the same Systems and methods are disclosed to produce a books in which interior staples are hidden. One disclosed example apparatus includes a sensor to detect a position of a book being produced on a binding line. The example book includes signatures coupled by a fastener. The fastener separates a first signature portion from a second signature portion of a first signature. The example apparatus also includes an adhesive dispenser to dispense adhesive to at least one of on or adjacent the fastener to couple the first signature portion and the second signature portion along a first fold adjacent the fastener. The example apparatus also includes a controller to cause the adhesive dispenser to dispense adhesive based on the position of the book detected by the sensor.
US10071584B2	Process for creating sub-surface marking on plastic parts Techniques or processes for providing markings on products are disclosed. In one embodiment, the products have housings and the markings are to be provided on sub-surfaces of the housings. For example, a housing for a particular product can include an outer housing surface and the markings can be provided on a sub-surface of the outer housing surface yet still be visible from the outside of the housing. Since the markings are beneath the surface of the housing, the markings are durable.
US10071582B2	Apparatus and methods for labeling vials or ampoules stored at temperatures as low as -200° C This invention relates to an apparatus and method for applying writings and other markings to a frozen vial or ampoule, which is filled with biological material, and which is held at temperatures between about −70° C. and about −196° C. More particularly, the invention relates to a laser marking method that allows frozen vials to be labeled, while maintaining the integrity of the biological material contained therein.
US10071578B2	Mounting device Examples of a mounting device and method are disclosed herein. An example of the mounting device includes a carriage to hold a printhead assembly and an interconnect assembly to supply printing composition to the printhead assembly. The mounting device also includes a first latching assembly having an engaged condition to lock the interconnect assembly to a manifold of the printhead assembly and a disengaged condition to unlock the interconnect assembly from the manifold of the printhead assembly. The mounting device additionally includes a second latching assembly having an engaged condition to lock the printhead assembly to the carriage and a disengaged condition to unlock the printhead assembly from the carriage. In this example of the mounting device, the second latching assembly cannot be moved from the engaged condition to the disengaged condition unless the fast latching assembly is in the disengaged condition.
US10071575B2	Printers and methods for detecting print media thickness therein Printer is provided having support base on which print media travels. Printer includes thickness detection module and processor. Thickness detection module includes pinch arm assembly with pinch arm having first and second ends, encoder, and proximate dual channel encoder sensor. First end is biased toward support base. Encoder with number of circumferentially spaced line pairs is disposed at second end. Pinch arm and encoder configured to rotate in response to engagement of pinch arm with at least print media portion. Dual channel encoder sensor configured to detect rotation direction and encoder count and output signal representing encoder count. Encoder count is number of circumferentially spaced line pairs that pass by dual channel encoder sensor as pinch arm and encoder rotate. Processor is communicatively coupled to dual channel encoder sensor and configured to receive signal and calculate print media thickness of portion from encoder count using conversion factor.
US10071574B2	Printer A printer comprises a housing which is composed of a box-shaped main body section with an opening on one surface thereof and a cover for opening and closing the opening of the main body section and forming a paper discharge port between the cover and the main body section at the time the cover is located at a position to close the opening; a storage section houses a roll paper; a printing section carries out printing on the paper; a cutter which has a cutting edge used to cut the paper; a support section which supports the cutter in a manner of freely moving between a use position at the time of cutting the paper by the cutting edge and a non-use position close to an edge of the paper discharge port with respect to the use position.
US10071569B2	Printer and method for manufacturing printed material In a printing method in which a base layer is formed with glossy ink or the like, a longer time period for drying the base layer is ensured. A metallic ink nozzle section, a superimposed colored ink nozzle section configured to discharge superimposed colored ink that is to be superimposed onto a metallic ink layer, and a non-superimposed colored ink nozzle section configured to discharge colored ink onto a position at which no metallic ink layer has been formed are provided. The non-superimposed colored ink nozzle section is interposed between the metallic ink nozzle section and the superimposed colored ink nozzle section.
US10071563B2	Digital print with water-based ink Water-based ink including a pigment mix and a method to form a digital print on a substrate with a pigment mix comprising large pigments and a Piezo ink head equipped with an ink circulation system, the method including: providing a water-based ink including an aqueous pigment mix including settling pigments, a binder including an acrylic resin dispersion, and a viscosity increasing substance including glycol and/or glycerine, providing a steric stabilization of the pigments and adapting the size of the pigments and the viscosity of the water-based ink such that a settling velocity of the pigments exceeds about 0.001 mm/min at 25° C., circulating said water-based ink within said at least one Piezo print head, and printing a digital image with said at least one Piezo print head by applying ink drops of said water-based ink on the substrate.
US10071559B2	Self-sealing filter module for inkjet printing A filter module (38) for a continuous inkjet printer (10) comprising a filter housing (40) and a filter medium (42) fixed within the housing (40). The filter housing (40) further includes an inlet portal (44) through which ink flows into the housing under pressure and a first self-sealing valve assembly (54) disposed within the inlet portal. In addition, housing includes an outlet portal (46) through which ink flows out of the housing (40) under pressure and a second self-sealing valve assembly (56) disposed within the outlet portal (46). The first and second valve assemblies (54, 56) open when mechanically connected to an ink flow path (34) from an ink tank (18) to a print head (14), and the first and second valve assemblies (54, 56) seal closed when mechanically disconnected from the ink flow path (34).
US10071558B2	System, control method therefor, printing apparatus, and control method therefor A system comprises: an obtaining unit that obtains predetermined information relating to amount of printing materials for a tank attached to a printing apparatus; and a determining unit that determines an interchangeable tank to be provided from a plurality of types of interchangeable tanks based on the predetermined information, wherein the plurality of types of interchangeable tanks include a first tank and a second tank, the first tank contains printing materials of at least two colors, with a ratio of amounts of the printing materials of the at least two colors being a first constituent ratio, and the second tank contains printing materials of at least the same two colors as those in the first tank, with a ratio of amounts of the printing materials of at least the two colors being a second constituent ratio different from the first constituent ratio.
US10071552B2	Sensing a property of a fluid In an example, a device for sensing a property of a fluid may include an ion-sensitive field effect transistor (ISFET) having a gate, a source, and a drain. The device may also include a first metal element in contact with the gate and a switching layer in contact with the first metal layer. A resistance state of the switching layer is to be modified through application of an electrical field of at least a predefined strength through the switching layer and is to be retained in the switching layer following removal of the electrical field. The device may also include a metal plate in contact with the switching layer, in which the metal plate is to directly contact the fluid for which the property is to be sensed.
US10071549B2	Printhead position control Systems and methods for printhead position control. The system comprises a controller that identifies a target distance for moving a printhead in a lateral direction to compensate for lateral shifts in a web of print media as the web travels in a continuous-forms printer in a conveyance direction. The controller also identifies a maximum distance for moving the printhead in the lateral direction based on an allowable print error in a color plane of the printer and one or more previous positions of the printhead. The control further moves the printhead for a distance that is a lesser of the maximum distance and the target distance.
US10071547B2	Typesetting grid system A three dimensional typeset apparatus is disclosed having a grid with a plurality of apertures for accommodating a plurality of sorts. The grid can accommodate sorts having a variety of dimensions and shapes. Each of the sorts has two sides, one side with a raised print surface and the opposite side which is a mirror image of the print side which enables the user to see how the layout looks when it prints. The sorts can print a single character or can print enlarged continuing images. A variety of attachments to secure each sort within the grid is disclosed.
US10071537B2	Ceramic matrix composite component and method of forming thereof A method of forming a ceramic matrix composite component is provided. The method includes applying a first amount of adhesive across a surface of a release film, providing a first ceramic foam panel including a plurality of channels formed on a first side of the first ceramic foam panel, contacting the first ceramic foam panel and the release film such that adhesive transfers to the first side of the first ceramic foam panel, and coupling the first ceramic foam panel to a second ceramic foam panel.
US10071535B2	Dunnage supply daisy chain stabilizer A rolled sheet-material supply handling-system that comprises a drawing device that can be configured to draw sheet material from a supply station and a stabilizer at the supply station. The stabilizer can define a generally tubular roll-receiving space in which a roll of the sheet material can be received and can have a support surface that can define an axial opening leading from the roll-receiving space to receive the sheet material drawn therefrom by the drawing device. The support surface can be sufficiently extensive to stabilize the outer layer of a roll against collapsing when the remainder of the roll has been extracted from the axial opening.
US10071534B2	Folding unit and method for producing pourable food product packages A folding unit for producing folded packages of pourable food products from sealed packs, comprising: movable conveyor which are fed with a plurality of packs at an input station, which feed packs along a forming path and output folded packages at an output station; and folder cooperating with each pack to perform at least one folding operation on pack comprising: at least one pair of shells which are integrally movable along the forming path and are movable relative to each other along a direction transversal to the forming path; shells of each pair may be set along the direction in: a fully closed position in which they exert a pressure onto a relative pack, so as to at least complete a folding operation onto relative pack; and an open position in which they are detached from the corresponding folded package.
US10071532B2	Rotor blades having thermoplastic components and methods of assembling same The present disclosure is directed to a method of assembling a modular rotor blade of a wind turbine. The method includes identifying a main blade structure, constructed at least in part, from at least one of a thermoset or a thermoplastic material. The method also includes identifying at least one blade segment, constructed at least in part, of a thermoplastic material reinforced with at least one of glass fibers or carbon fibers. Thus, the method also includes securing the at least one blade segment to the main blade structure, e.g. via welding.
US10071528B2	Stiffened thin-walled fibre composite products and method of making same Stiffened thin-walled natural fiber composite product having first fiber yarns (A), each first fiber having a first thickness, and second fiber yarns (B) having a second thickness larger than the first thickness. At least one side of said product is even. Applications for a seat post; a bicycle saddle; a bicycle frame; a bicycle handle bar; a baseball bat; a piece of furniture; a paddle; or a sheet for automotive applications.
US10071527B2	Colour 3-dimensional printing with 3D gamut mapping Provided is a Layered Object Manufacturing, LOM, system configured to form a colored three-dimensional (3D) object, the system comprising: a 3D object gamut mapping module configured to define a 3D object formed from a plurality of surfaces and provide a printing regime consistent with the defined 3D object, wherein the 3D object gamut mapping module is configured to analyze the orientation of a surface of each of a plurality of media layers to be printed in order to adaptively modify the color printed to that layer; and a printer configured to color print at least a portion of a first surface of each of the plurality of layers in accordance with the printing regime. Also provided is a color 3D object media layer printing module for providing a print-through region in a 3D object media layer. Also provided is a 3D object gamut mapping method, and ink for use in a Layer Object Manufacturing (LOM) system including the printing module.
US10071526B2	Adaptation method and production method for components produced by SLM An adaptation method for a modelling method in which, by means of target geometry, model geometry, which is derived from the target geometry, is created for an object to be produced by a selective laser melting method is provided. In the adaptation method, adapted model geometry is produced from the derived model geometry by dimension adaptation by means of a correction factor and/or by geometry adaptation by means of correction geometry.
US10071521B2	Method and apparatus for processing dielectric materials using microwave energy Methods and systems are provided for heating a dielectric preform material. An exemplary method includes inserting the preform material into a microwave cavity along a longitudinal axis of the microwave cavity and supplying the microwave cavity with microwave power having a frequency that corresponds to an axial wavelength along the longitudinal axis of the microwave cavity. The axial wavelength is greater than a length of the preform material along the longitudinal axis. The method includes heating the preform material within the microwave cavity by the microwave power and determining temperatures of the preform material at one or more locations on a surface of the preform material. The method further includes adjusting, based on the temperatures of the preform material, the microwave frequency to achieve substantially uniform heating at least on a sidewall of the preform material along the longitudinal axis.
US10071516B2	Mold for manufacturing reel component member, method of manufacturing reel component member, and method of manufacturing reel A mold for manufacturing a reel component member, the mold comprises a hub formation portion configured to form a circular tube shaped hub; a flange formation portion configured to form a flange integrally provided at one end portion of the hub; a bottom plate formation portion configured to form a bottom plate that is provided with a ring shaped reel gear at the one end portion or another end portion of the hub and that includes a plurality of hole portions provided at equal intervals on the reel gear; a gate that is disposed further to a radial direction inside than a wall face of the hub formation portion that is configured to form an inner peripheral face of the hub; and an anticorrosion coating that is applied to a wall face of the hub formation portion that is configured to form an outer peripheral face of the hub.
US10071515B2	Mould equipment for pipeline section coating and methods for coating of pipeline sections with moulds A mold for coating a pipeline section with molten coating material from an injection molding machine, wherein the mold Includes a shell of impervious material reinforced by an exoskeleton of non-distensible material. An assembly for supporting a mold including a plurality of mutually separable shell bodies for coating a pipeline section, wherein the assembly includes motorized opening and closing of the shell bodies in a straight line. An assembly for supporting a bent pipeline section wherein the assembly includes a base and a pair of arms extending from the base, wherein each arm includes a respective clamping collar for clamping a bent pipe section between the arms. A vehicle for induction heating a bent pipeline section, wherein the vehicle includes a helical induction coil; and wheels arranged to guide movement of both ends of the induction coil through a tubular inside face of a bent pipeline section.
US10071512B2	Method for manufacturing liquid-ejecting head Provided is a method for manufacturing a liquid-ejecting head whereby in die slide injection molding it is possible to stably inject resin in secondary molding without damaging the shapes of parts that were formed in primary molding. In order for that, in the connecting section in which a convex section of a cover member is inserted into an opening of a liquid-supply member, the closest distance to the opening in the area where secondary resin is injected is made larger than the gap between the opening and the convex section. As a result, the resin is prevented from flowing into a liquid path during the secondary molding.
US10071509B2	Arrangement for manufacturing a heat winding cap The present disclosure relates to an arrangement for manufacturing a head winding cap of an electric machine, comprising a container for accommodating a molding compound, the container is attachable to two winding arms adjacent to a clip connecting the winding arms and enclosing the winding arms, the container projecting perpendicular to the winding arms when attached, and the container creating a tight inclusion for the molding compound, whereas the cap is filled with a dielectric compound.
US10071505B2	Method for producing a semi-finished product to be made into a CFRP component, from carbon-fiber scrap A method is provided in which suitable carbon-fiber scrap is fed, together with a plastic polymer, to a pulverizer and extruder in order to produce a carbon-fiber polymer mass therefrom and to impregnate the mass with a resin. A regrind prepreg, which is given suitable forms and/or lengths, is thus obtained. The regrind prepregs thus obtained can then be given an approximately final form in an additional step by way of an extrusion process.
US10071499B2	Safety systems for power equipment Machines with safety systems are disclosed. The machine may take the form of woodworking machines including table saws, band saws, miter saws, hand-held circular saws, pneumatic chop saws, radial-arm saws, jointers, planars, routers and shapers. The machines may include an operative structure configured to perform a task, where the operative structure includes a cutting tool adapted to move in at least one motion, and a safety system adapted to detect the occurrence of an unsafe condition between a person and the cutting tool and for mitigating the unsafe condition. The safety system may include a detection subsystem and a reaction subsystem. The machine may also include a bypass or override mode where in an injury mitigation system is disabled for certain cuts.
US10071496B2	Blade and blade mount for a cutting machine A blade mount for a cutting machine, in particular for a food slicing machine, includes a contact surface for a blade, a mount section for the blade projecting axially from the contact surface and at least one torque transmission element which projects axially from the contact surface, which is radially spaced apart from the mount section, which engages into the blade and in which a mount is formed for fastening the blade to the blade mount. Additionally, a blade is matched thereto, to a handling apparatus for assembling the blade at the blade mount, and to a system of blade mount, blade and handling apparatus.
US10071491B2	Electric hair trimmer A cutter head for an electric hair trimmer generally includes a cutting assembly having a stationary blade, a movable blade, and a follower connected to the movable blade. The electric hair trimmer has a handle with a drive system and an ejection mechanism. The follower is configured for operative connection with the drive system of the handle for oscillating the movable blade relative to the stationary blade. The cutter head also includes a housing having a tongue configured to provide clearance for the follower when the cutter head is ejected from the handle via the ejection mechanism.
US10071489B2	Locking folding knife A folding knife includes a lockbar for automatically locking a knife blade in an opened position relative to a handle. A puck attached to the lockbar is configured to engage a tang of the blade to lock the blade in an open position relative to the handle.
US10071487B2	Systems and methods for compiling robotic assemblies Systems and methods to systematize the development of machines using inexpensive, fast, and convenient fabrication processes are disclosed. In an embodiment, a robot compiler generates a fabrication system, including mechanical, electrical, and software assemblies, that can be used for assembling a robot according to a user design.
US10071482B2	Robotic vehicle painting instrument including a terahertz radiation device A method comprising scanning a first painted surface of a first vehicle having two or more paint layers with a robotic terahertz radiation instrument to obtain a first painted surface thickness data and map for each of the two or more paint layers, comparing the first thickness map to a control map, and adjusting one or more paint application parameters based on a comparison of the first thickness map with the control map for painting a second surface of a second vehicle different than the first vehicle.
US10071481B2	Safety system for industrial robots A system to secure people's safety in places such as a factory wherein people and industrial robot collaborate with each other in a state that a physical fence surrounding the preferred industrial robot's working region is excluded. The system is capable of acquiring respective distances between robot and a plurality of people. Furthermore, a critical distance of each person is set on the basis of at least one of personal information that each person individually has and environment information to be set depending on the robot's setting environment. A mounted-type monitor is respectively mounted on the plurality of people and is capable of displaying information within a view of each person, and a control unit is capable of controlling display content thereon. According to the display control, when a distance between robot and each person becomes less than a critical distance, the distance state is displayed on the mounted-type monitor.
US10071480B2	Real-time interference check system of machine tool and robot An interference check system capable of appropriately checking interference between a machine tool and a robot in real time even in the case where real-time properties of data communication are not secured in a system including a machine tool and a robot. The interference check system includes a machine tool controller configured to control a machine tool, a robot controller configured to control a robot, and an interference check execution unit configured to include shape model data or the like of a machine tool mechanical unit and a robot mechanical unit. The interference check execution unit checks presence/absence of interference between the machine tool mechanical unit and the robot mechanical unit based on the shape model data of the machine tool and the robot and time-series data generated by integrating the positions of the control axes of the machine tool and the robot, respectively.
US10071471B2	Pry bar handle A pry bar has a transversely disposed generally triangular cross-section handle grip portion having surfaces formed of a soft elastomeric over-molded material. The handle is formed with an inner hard thermoplastic core and molded over outer elastomeric cover. A metal tether receiving element and impact cap are fixedly secured at the handle proximate end.
US10071470B2	Handle for cleaning tool or similar Handle for cleaning tool or similar which has an elbow at an intermediate point which defines a lower straight section and an upper section which externally forms a widened surface with a configuration and length adapted to the forearm of an individual which at the front end ends in a flexible clamp which secures the forearm of the user in an area close to the elbow while on the same exterior face and close to the angled area of the handle there is a handhold in such a manner that it can be applied both on the ground or on a low surface as well as on the ceiling or an elevated surface above the head of the user.
US10071469B2	Foldout hand tool A generally continuous cylindrical body where a first set of tools and a second set of tools are arranged at the proximate and distal ends of the body to rotate in a specific alternating 180 degree sequence in either an “L” mode or “screwdriver” mode for use. The tools are configured to be positioned at one or more hinge points by screws and shoulder screws. At a proximal end of the tool body, and at the tangent of the circumference of the body at the distal end of each tool; each tool is configured to rotate away from the body to a plurality of angles. The general cylindrical body also provides angled channels or walls with varying angular depths or tool slots where the tools are arranged and retained within the general cylindrical body.
US10071468B2	Hand-power tool with an oscillation-damping device A hand-power tool includes at least one oscillation-damping device that has at least one damping spring, a damping mass, and a mechanism housing. The oscillation-damping device has at least two retaining parts that at least partly enclose the damping mass.
US10071465B2	Grindstone tool A grindstone tool is provided with a shaft part which has a tubular shape having a connection hole therein, a head part which has a cylindrical shape coaxially and integrally connected to the leading end of the shaft part and having a hollow section therein, and abrasive grains which adhere to the entire outer peripheral surface of the head part via a bonding material. A grinding fluid is supplied to the hollow section of the head part from one end side of the head part, the other end side of the head part is blocked by a lid member, and in the head part, a plurality of communication holes through which the hollow section and the outer peripheral surface communicate with each other, and which each have a taper shape with a diameter size on the outer peripheral surface side larger than a diameter size of the shaft center side are formed.
US10071460B2	Polishing pad and method for producing polishing pad Provided are a method for producing a finish polishing pad and the polishing pad which allow formation of a stable film and enables polishing with fewer polishing scratches. The method includes the steps of: dissolving a composition for forming polyurethane resin film containing a polyurethane resin and an additive(s) in a solvent capable of dissolving the resin; removing an insoluble component(s) to make the content of the insoluble component(s) in the solution less than 1% by mass relative to the total mass of the composition; adding a poor solvent to the solution from which the insoluble component(s) has(have) been removed, followed by mixing, the amount of the poor solvent added being calculated according to a defined Formula 1; and forming a film from the mixture solution on the film formation substrate by a wet coagulation method, to thereby form the polyurethane resin film.
US10071458B2	Calibration apparatus and calibration method An object of the invention is to provide a calibration apparatus which enables the pressing force of the polishing pad to be adjusted by a simple method without the need of removing a stage on which a substrate can be placed. One embodiment of the invention provides a calibration apparatus for a bevel polishing system for polishing a bevel portion of a substrate, comprising: a load measuring device capable of measuring a pressing load from a polishing pad of the bevel polishing system; and a base plate capable of having the load measuring device placed thereon, wherein the base plate is capable of being fixed on a vacuum suction table which is capable of having a substrate placed thereon.
US10071456B2	Automated hardwood texturing system and associated methods A system and method for imparting a textured surface effect in a board. The system and method are configured to releasably secure a charge on a table; determine a random abrasion pattern for the charge with at least one programmable controller; and control at least one abrasion assembly with the at least one programmable controller in accord with the random abrasion pattern to selectively engage and remove desired portions of the upper surface of the charge with the at least one abrasion assembly to form a randomized textured surface effect thereon.
US10071452B2	Automated end effector component reloading system for use with a robotic system An automated reloading system for replacing a spent surgical end effector in a manipulatable robotic tool portion of a robotic surgical system is disclosed. The automated reloading system comprises a drive assembly configured to generate rotary drive motions and a selectively movable support assembly defining a plurality of end effector reloading positions. Each reloading position being configured to support a new surgical end effector or a spent surgical end effector therein. The selectively movable support assembly being further configured to selectively serially move each reloading position into a driving position wherein the new surgical end effector or the spent surgical end effector therein is configured to selectively receive the rotary drive motions. The automated reloading system further comprises means for releasably locking the movable support assembly in the driving position during the application of the driving motion to the new surgical end effector or the spent surgical end effector.
US10071449B1	Irrigation insertion tool and method An irrigation insertion tool is disclosed for inserting an irrigation emitter into an irrigation tubing. The irrigation insertion tool comprises a primary lever including a primary fulcrum base coupling a primary handle and a primary jaw. A secondary lever includes a secondary fulcrum base coupling a secondary handle and a secondary jaw. A couple joins the primary fulcrum base and the secondary fulcrum base for defining a fulcrum. A tubing channel is in the primary jaw for receiving the irrigation tubing. An emitter socket is in the secondary jaw for receiving the irrigation emitter. The primary handle and the secondary handle converge for generating a mechanical advantage between the primary jaw and the secondary primary jaw. The primary jaw and the secondary jaw compress the irrigation tubing with the irrigation emitter and pierce the barb tube through the irrigation tubing.
US10071446B2	Apparatus for repairing a cylinder head An apparatus and method are presented for repairing damage to the boundary wall between an engine coolant passage and a fuel injector bore in a cylinder head. The method involves removing the fuel injector from the fuel injector bore adjoining the damaged boundary wall and inserting a purpose-built sealant injector tool into the fuel injector bore. The sealant injector tool is dimensionally equivalent to the fuel injector in critical regions so that it conforms to the interior surface of the fuel injector bore. Sealant is injected into the sealant injector tool at high pressure until the sealant flows into the crack between the fuel injector bore and the coolant passage after which the sealant injector tool is removed and the fuel injector reinstalled.
US10071441B2	Method for producing a hollow body which is pressure-tight to a predetermined medium A method for producing a hollow body that is pressure-tight for a predetermined medium through the joining of at least two sub-bodies, which when joined form the hollow body that contains the medium in a gaseous and/or liquid state during the intended use of the hollow body; the at least two sub-bodies are integrally joined by means of an integral joining method that can be successfully performed at ambient pressure; the medium is introduced into at least one sub-cavity of at least one sub-body in a solid or partially solid state before the integral joining is performed, the medium is introduced together with a container element that contains or holds the medium in a solid or partially solid state, from which containing element the medium can escape in the liquid or gaseous state; and then the integral joining is carried out.
US10071439B1	Method and system of joining thick sheets of non-weldable material using ultrasonic joining A method and system for joining relatively thick (i.e., at least 0.07 inch, or between 0.08 and 0.24 inch) sheets of non-weldable aluminum or other material using multiple passes of ultrasonic joining and multiple plugs to create a single larger sheet. Angles and profiles are machined onto edges of the sheets, the angles are overlapped to form a scarf joint, and ultrasonic joining is performed on both sides of the scarf joint, resulting in channels where the angles and profiles intersect. Plugs are extruded or otherwise created and positioned in the channels, and ultrasonic joining is used to join the plugs in the channels. Additional plugs are added until the last plugs are proud of the surface, and then the plugs are machined until the joint is flush with the surface. The plugs may be of the same or a different material as the sheets.
US10071434B2	Intelligent waveform selection for a welding system having particular electrical output characteristics Systems and methods for selecting a welding output waveform based on characterizing a welding circuit output path with respect to its electrical characteristics. At least one electrical characteristic (e.g., inductance, resistance) of a welding output circuit path connected to a welding power source is determined. A welding output waveform is selected from a plurality of welding output waveforms based on the determined electrical characteristics. As a result, the selected welding output waveform is matched to the welding output circuit path electrical characteristics to provide superior welding performance.
US10071432B2	Power tool with arbor lock A power tool assembly includes a latch movable between a first latch position whereat the latch supports a drop arm assembly in a first drop arm assembly position, and a second latch position whereat the latch does not support the drop arm assembly position at the first drop arm assembly position, and an arbor lock movable between a first lock position whereat the arbor lock prevents movement of the drop arm assembly toward the second drop arm assembly position when the drop arm assembly is in the first drop arm assembly position, and a second lock position whereat the arbor lock does not prevent movement of the drop arm assembly toward the second drop arm assembly position when the drop arm assembly is in the first drop arm assembly position.
US10071431B2	Four-sided shimable indexable shear tip boot A one piece four-sided hardened steel boot tip is mounted to a distal end upper jaw tang of a heavy duty demolition. The boot tip has a front wall seated on the tang front edge and a right side wall seated on the shear side tang face and radiused or curved rear seat. A top wall has a radiused inside top wall that sits on the radiused tang top seat. A bottom wall of the boot tip has a radiused inside top wall that is seated on the tang radiused bottom seat forming a shear punching edge between the front wall and the bottom wall. The boot tip has a shear side shearing edge that is between the sidewall and the bottom wall of the boot tip. An access or side plate is seated on the guide side tang face, a portion of the radiused boot bottom wall and the radiused rear seat. The side plate is flush with the bottom and front walls. The boot tip right side and access plate have matching apertures therethrough and alignable with the tang apertures to secure the boot and access plate to the tang for encapsulating protection thereof from the lower jaw shear side, the guide side and the tie plate as the upper jaw moves into and out of the recess therebetween. One or more shims may be provided that are insertable inside the boot against the tang faces and clampable thereto after the faces have become worn or otherwise requires adjustment for maximum clamping force.
US10071430B2	Cutting head, rotary tool and support for the rotary tool and for the accommodation of the cutting head A cutting head is formed for insertion into a support in a modular rotary tool, in particular a drill. The coupling head has a coupling having torque surfaces and clamping surfaces on its outer periphery. The coupling pin is divided into a front pin part and a rear pin part. The front pin part is defined by a circumferential groove. Stop surfaces for an axial pullout safety are formed in the transition area between the two the front pin part and the rear pin part. The torque surfaces and the clamping surfaces are arranged in different pin parts. For example, the clamping surfaces are preferably formed on the front pin part and the torque surfaces are preferably formed in the rear pin part.
US10071425B2	Method for fabricating metal foams having ligament diameters below one micron A method for fabricating a metal foam component from an aerogel containing a polymer and nanoparticles is disclosed. The method may comprise: 1) exposing the aerogel to a reducing condition at an elevated temperature for a reaction time to provide a metal foam; and 2) using the metal foam to fabricate the metal foam component. At least one of the elevated temperature and the reaction time may be selected so that at least some ligaments of the metal foam have a desired ligament diameter or at least some pores of the metal foam have a desired pore size. The desired ligament diameter may be less than about one micron and the component may be a component of a gas turbine engine.
US10071422B2	Skillful three-dimensional printing The present disclosure various apparatuses, and systems for 3D printing. The present disclosure provides three-dimensional (3D) printing methods, apparatuses, software and systems for a step and repeat energy irradiation process; controlling material characteristics and/or deformation of the 3D object; reducing deformation in a printed 3D object; and planarizing a material bed.
US10071421B2	Flaky magnetic metal particles, pressed powder material, rotating electric machine, motor, and generator The flaky magnetic metal particles of the embodiments include a plurality of flaky magnetic metal particles, each of the flaky magnetic metal particles including a first magnetic particle including a flat surface, at least one first element selected from the group consisting of Fe, Co and Ni, an average ratio between the maximum length and the minimum length in the flat surface being between 1 and 5 inclusive, an average thickness of the first magnetic particles being between 10 nm and 100 μm inclusive, an average aspect ratio of the first magnetic particles being between 5 and 10000 inclusive; and a plurality of second magnetic particles disposed on the flat surface, an average number of the second magnetic particles being five or more, an average diameter of the second magnetic particles being between 10 nm and 1 μm inclusive.
US10071417B2	Insert for die cast shot sleeve A shot sleeve for use in a die cast assembly has a shot sleeve body extending along an axis and having a bore for receiving a plunger. An insert is secured at a shot end of the shot sleeve body. A die cast assembly is also disclosed.
US10071414B2	Tool and method for processing a workpiece with a tool element of a tool A tool for processing a workpiece has a tool element for processing the workpiece and a control device. The control device is configured to evaluate a rotation angle, which is detected by a detection device, and with which the tool is arranged in space, after a processing operation of the workpiece has been carried out with the tool element. The control device is also configured to release the control of the tool in a manner dependent on whether the tool has been arranged in space with a predetermined rotation angle after the workpiece has been processed.
US10071413B2	Device for assembling products in die The present invention discloses a device for assembling products in a die. The device comprises a pushing portion and an assembling portion. The pushing portion comprises a pushing block (11), a pushing spring (10) and a pushing wedge (9) wherein the pushing block (11) is connected with the pushing spring (10), the pushing wedge (9) is arranged above the pushing block (11) and is in wedge-shaped connection with the pushing block (11). The assembling portion comprises an assembling wedge (6), a transmission wedge (4) and an assembling male die (5), wherein the transmission wedge (4) is arranged above the assembling male die (5) in wedge-shaped connection and both of them are arranged in the lower die base (2), the assembling wedge (6) is arranged above the transmission wedge (4) in wedge-shaped connection while in contact.
US10071412B2	Method for assembling products in die The present invention discloses a method for assembling products in a die by the aid of a device for assembling products in a die. The device for assembling products in the die comprises a pushing portion and an assembling portion. The pushing portion comprises a pushing block (11), a pushing spring (10) and a pushing wedge (9), wherein the pushing block (11) is connected with the pushing spring (10), and the pushing wedge (9) is arranged above the pushing block (11) and is in wedge-shaped connection with the pushing block (11). The assembling portion comprises an assembling wedge (6), a transmission wedge (4) and an assembling male die (5), wherein the transmission wedge (4) is in wedge-shaped connection with the assembling male die (5), and the transmission wedge (4) and the assembling male die (5) are arranged in a lower base (2).
US10071410B2	Manufacturing apparatus and manufacturing method for stretch-formed product There is provided a manufacturing apparatus and a manufacturing method for a stretch-formed product which can improve the yield of material in the stretch forming performed while clamping the blank by the lock beads. The manufacturing apparatus for a stretch-formed product includes a die and a blank holder which have clamping surfaces facing each other, a punch that, in a state where a margin of a blank of a sheet material is clamped by the clamping surfaces of the die and the blank holder, relatively presses a forming region of the blank into the die and thereby performs stretch forming on the forming region of the blank, and lock beads that are provided on the clamping surfaces of the die and the blank holder in mutually similar shapes and have first surfaces, second surfaces that intersect with the first surfaces, and third surfaces that intersect with the second surfaces from outer edges toward the centers of the die and the blank holder, the first surfaces each having a plurality of depression-protrusion parts.
US10071407B2	Apparatus for controlling camber and method for same Provided is a camber control apparatus and method capable of reducing camber of a slab sizing press (SSP). The camber control apparatus and method may calculates a camber amount through an imaging process and differently set zeroing of anvils at a work side and a drive side, thereby reducing camber. Thus, the camber control apparatus and method can reduce quality defects such as telescope, twist, wave, and roll mark, increase the lifetime of equipment by reducing a variation in load applied to the equipment, and minimize a cost caused by an equipment accident.
US10071405B2	Apparatus for thermal treatment of organic waste The present disclosure provides an apparatus for thermal treatment of a pre-defined amount of organic waste. The apparatus includes a plurality of chambers to receive the pre-defined amount of organic waste. Further, the apparatus includes a double wall to encapsulate each of the plurality of chambers. Furthermore, the apparatus includes an auger accommodated within the cylindrical hollow body of each of the plurality of chambers. Moreover, each of the plurality of chambers has a cylindrical hollow body. The cylindrical body has a first diameter of a first section and a second diameter of a second section. In addition, each of the plurality of chambers is connected in succession for a continuous movement of the pre-defined amount of organic waste along a longitudinal axis. Further, the plurality of chambers includes a feed material inlet and a processed material outlet attached at a second end of the plurality of chambers.
US10071403B2	System and method for decomposing municipal solid waste (MSW) under anaerobic conditions A system and method for decomposing municipal solid waste (MSW) under anaerobic conditions. The system includes a bioreactor landfill with the MSW, a leachate recirculation unit in connection with the bioreactor landfill, a multilevel thermocouple unit, placed inside the bioreactor landfill for monitoring temperature in the bioreactor landfill. Further, the system includes a sensor for monitoring moisture level within the bioreactor landfill. Furthermore, the system includes the leachate recirculation unit configured to initiate recirculation of a leachate, collected from the bioreactor landfill, when temperature in the bioreactor reaches a determined temperature and a determined moisture level.
US10071402B2	Method for sterilizing water treatment apparatus having plurality of tanks Provided is a method for sterilizing a water treatment apparatus having a plurality of tanks. The method includes, performing a sterilization preparation process to drain purified water from the first tank until a first amount of purified water is left, performing a sterilizing process to sterilize the first tank by supplying the sterilized water supplied from the sterilizing module, to drain water from the first tank through a first water outlet pipe until a second amount of water is left in the first tank, and to drain the second amount of water remaining in the first tank into the second tank through a second water outlet pipe.
US10071390B2	Fluidized bed coating apparatus A fluidized bed coating apparatus for coating liquid onto the surfaces of particles directed into a coating chamber. A liquid spray nozzle assembly disposed below a hollow separator within the coating chamber includes an ultrasonic atomizer for atomizing coating liquid into a fine liquid particle cloud and a pressurized air directing air cap for forming the ultrasonically atomized fine liquid particle cloud into a cone shaped spray pattern and propelling the liquid particles through the separator into an upbed region of the coating chamber for recirculation in an outbed region, and through the separator. A cooling air passageway system is provided within the spray nozzle assembly for cooing the ultrasonic atomizer during operation.
US10071388B2	Liquid spray gun, spray gun platform, and spray head assembly Liquid spray gun platforms, spray head assemblies and liquid spray guns including one or both of the spray gun platforms and the spray head assemblies are described.
US10071387B2	Apparatus and method for coating object by supplying droplet to surface of the object while applying active species to the droplet A coat forming apparatus 100 includes a droplet supply unit 110 and an active species supply unit 120. The droplet supply unit 110 is adapted to spray or drop a droplet for coat forming toward an object 116. The active species supply unit 120 is adapted to supply an active species to be brought into contact with the droplet moving from the droplet supply unit 110 toward the object 116. The coating is formed on a surface of the object 116 by the droplet that has been brought into contact with the active species.
US10071383B2	High-volume fast separation of multi-phase components in fluid suspensions A flow chamber is provided through which is flowed a mixture of a fluid and a particulate. The flow chamber comprises at least one multi-phase water inlet through which multi-phase water enters the flow chamber, a water outlet through which water exits the flow chamber, a solids outlet through which particles having a density at or above a pre-defined threshold exit the flow chamber, and a low density outlet through which particles having a density below the pre-defined threshold exit the flow chamber. Also provided are one or more ultrasonic transducers and one or more reflectors corresponding to each transducer to acoustically filter the fluid and cause particles/fluid to be selectively diverted to one of the outlets. Related apparatus, systems, techniques and articles are also described.
US10071380B2	Storage container for biosensor test elements A component for a storage container configured to receive vertically oriented articles. The component includes a tubular sidewall extending longitudinally from a base, and at least one spacer portion extending from an underside of the base and configured for engagement with an interior surface of a corresponding storage container. The component also includes at least one pair of retainer elements extending laterally from an inner surface of the tubular sidewall and inwardly into an interior region of the component, and with the retainer elements being oppositely oriented and configured to retain a vertically oriented article therebetween by frictional engagement with opposite longitudinal edges of the article, and wherein an insertion force for resilient deflection of the retainer elements during insertion of the article is less than a removal force for resilient deflection of the retainer elements during removal of the article.
US10071379B2	Manipulation of fluids and reactions in microfluidic systems Microfluidic structures and methods for manipulating fluids and reactions are provided. Such structures and methods may involve positioning fluid samples, e.g., in the form of droplets, in a carrier fluid (e.g., an oil, which may be immiscible with the fluid sample) in predetermined regions in a microfluidic network. In some embodiments, positioning of the droplets can take place in the order in which they are introduced into the microfluidic network (e.g., sequentially) without significant physical contact between the droplets. Because of the little or no contact between the droplets, there may be little or no coalescence between the droplets. Accordingly, in some such embodiments, surfactants are not required in either the fluid sample or the carrier fluid to prevent coalescence of the droplets. Structures and methods described herein also enable droplets to be removed sequentially from the predetermined regions.
US10071372B2	Pipette for volumetrically metering powder A pipette for volumetrically metering powder includes an outer metering casing enclosing a metering chamber. The metering casing defines a free end of the pipette whereat the metering casing forms an opening. The metering chamber has an opposite end lying opposite to the free end of the pipette and the opposite end of the metering chamber is delimited by an air-permeable retaining element. The retaining element is configured as a flexible filter defining a plane and having a back side facing away from the metering chamber. An air-permeable support core supports the filter at the back side thereof and is rigid transversely to the plane of the filter.
US10071371B2	Compositions and methods for reducing atmospheric ozone levels Provided are ozone decomposing compositions comprising a solvent and a polymer. The polymer comprises a structural repeat unit comprising an unsubstituted or substituted carbohydrate moiety. Also provided are methods of decomposing ozone using the compositions, and spray coatings, items of clothing, fabrics, carpets, paints, sealants, finishes, air-filters, face-masks, cosmetics, creams, lotions and coatings incorporating the polymer.
US10071370B2	Method for reactivating used hydrogenation treatment titania catalyst, and regenerated hydrogenation treatment titania catalyst Provided is a method of reactivating a used titania catalyst for hydrogenation treatment, capable of improving the catalytic activity of the used titania catalyst for hydrogenation treatment that is obtained by supporting a catalyst component on a titania support and exhibits reduced catalytic activity after having been used for hydrogenation treatment of a hydrocarbon oil, to a level comparable to that of a newly prepared fresh titania catalyst before use. The method of reactivating a used titania catalyst for hydrogenation treatment, the used titania catalyst for hydrogenation treatment being obtained by supporting a catalyst component on a titania support and exhibiting reduced catalytic activity after having been used for hydrogenation treatment of a hydrocarbon oil, includes: a coke removal step of removing a carbonaceous component on a surface of the used catalyst by heating the catalyst in an oxygen-containing gas atmosphere; an impregnation step of impregnating the carbonaceous component-removed catalyst obtained by the coke removal step with a saccharide-containing solution; and a drying step of drying the saccharide-impregnated catalyst obtained by the impregnation step, to obtain a catalyst in which a saccharide is supported.
US10071368B2	Exhaust gas purification catalyst An exhaust gas purification catalyst capable of stably maintaining and exhibiting excellent catalytic performance includes a wall-flow-type substrate, a first catalytic layer and a second catalytic layer. The first catalytic layer is provided to an internal portion of a partition wall in contact with an entrance cell. The second catalytic layer is provided to an internal portion of a partition wall in contact with an exit cell. The ratio (D2/D1) of the coating density D2 of the second catalytic layer to the coating density D1 of the first catalytic layer is 1.01 to 1.4.
US10071366B2	Catalyst preparation method A method is described for preparing a catalyst including the steps of: (i) impregnating a calcined support comprising a metal aluminate with a solution of nickel acetate at a temperature ≥40° C. and drying the impregnated support, (ii) calcining the dried impregnated support, to form nickel oxide on the surface of the support and (iii) optionally repeating steps (i) and (ii) on the nickel oxide coated support. The method provides an eggshell catalyst in which the metal oxide is concentrated in an outer layer on the support.
US10071365B2	Catalytic converter There is provided a catalytic converter that offers high exhaust gas cleaning performance by effectively utilizing a whole catalyst that constitutes the catalytic converter.In a catalytic converter (10), catalytic layers (2A, 2B) made of a noble metal catalyst are formed on cell wall surfaces of a substrate (1) having a cell structure, and the catalytic layers (2A, 2B) extend in a longitudinal direction of the substrate (1) along which gas flows. The substrate (1) has a central region (1A) having a relatively high cell density and a peripheral region (1B) having a relatively low cell density. The length of each of the catalytic layers (2B) in the longitudinal direction in the peripheral region (1B) is longer than the length of each of the catalytic layers (2A) in the longitudinal direction in the central region (1A).
US10071361B2	Filter material for the selective removal of siloxanes A filter material is for the selective removal of siloxanes from a gas. The filter material contains a titanium compound, which is an organotitanate and/or a compound, which can be obtained by hydrolysis of an organotitanate. A method for the production of the filter material is also provided to use the filter material for the selective removal of siloxanes from a gas. A gas sensor is provided which includes the filter material.
US10071356B2	Moving bed catalytic reactor for managing interruptions to the circulation of catalyst, and process using said reactor The present invention describes a catalytic reactor operating as a moving bed to manage interruptions in the circulation of catalyst while at the same time avoiding mechanical damage to the contact means containing the catalyst. The invention also concerns a refining or petrochemicals process using the reactor in accordance with the invention.
US10071355B2	Cutting inserts and method for making same A method of making a cutter structure (1) comprises placing a pre-formed body (4) of hard material having a surface topography in a canister, placing an aggregated mass of grains of superhard material (2) over said surface topography, placing a punch (10) in contact with the superhard material (2), the punch (10) having a surface with a surface topography inverse to that of the hard material body to imprint a pattern in the superhard material (2) complementary to the surface topography of the punch (10). The surface of the punch (10) contacting the superhard material (2) being formed of a ceramic material that does not react chemically with the superhard material (12) and/or a sinter catalyst for the superhard material (2). A pressure of greater than 3 GPa is then together with a temperature sufficiently high for the catalyst to melt to form the cutter structure (1) with a layer of polycrystalline superhard material bonded to the hard material and having a surface topography corresponding to the surface topography of the hard material.
US10071343B2	Electrically heated catalyst device and its manufacturing method An electrically heated catalyst device 100 according to an aspect of the present invention includes a catalyst support 20 supporting a catalyst thereon, a thin plate-like wiring line member 40 fixed on an outer circumferential surface of the catalyst support 20, an outer cylinder 70 with an opening 71 formed on its side, the outer cylinder 70 covering the outer circumferential surface of the catalyst support 20, the opening 71 being configured for externally pulling out the wiring line member 40, and a holding member 60, the holding member 60 filling up space between the catalyst support 20 and the outer cylinder 70 and thereby holding the catalyst support 20, in which the catalyst support 20 is electrically heated through the wiring line member 40. A pull-out part 43 of the wiring line member 40 pulled out through the opening 71 is formed in an accordion shape.
US10071342B2	Three-way catalytic converter The present invention relates to a three-way catalytic converter for reducing harmful exhaust components of gasoline-powered internal combustion engines, and to a corresponding method for exhaust gas purification. The catalytic converter is characterized by a particularly inhomogeneous distribution of the oxygen-storing material present.
US10071337B2	Integration of staged complementary PSA system with a power plant for CO2 capture/utilization and N2 production Systems and methods are provided for combined cycle power generation while reducing or mitigating emissions during power generation. Recycled exhaust gas from a power generation combustion reaction can be separated using a staged complementary swing adsorption process so as to generate a high purity CO2 stream while reducing/minimizing the energy required for the separation and without having to reduce the temperature of the exhaust gas. This can allow for improved energy recovery while also generating high purity streams of carbon dioxide and nitrogen.
US10071333B2	Gas separation cartridge A gas separation cartridge including a housing comprising an inlet port for an air sample to enter; a top cover attached to the housing; an upper cavity comprising individual chambers comprised of a chemical or an absorbent or a mixture thereof attached to the top cover wherein each end of each chamber has an opening; a bottom cover attached to the upper cavity, wherein the bottom cover comprises a lower cavity, a separate opening for an air sample traveling from an individual chamber to pass through, and a separate opening for an air sample that does not pass through an individual chamber; and a base upon which the bottom cover of the cartridge is seated, wherein the base has an exit port.
US10071329B2	Air cleaner An air cleaner includes an upper casing, a lower casing, and a filter element, which is located inside the upper casing and the lower casing. The upper casing includes an inlet, a lower opening, and a peripheral wall, which defines the lower opening. The lower casing includes an outlet and covers the lower opening of the upper casing. A looped application surface is formed on the lower casing. The filter element is fixed to the lower casing with an adhesive applied to the application surface of the lower casing. A protrusion, which is formed on the peripheral wall of the upper casing, is inserted into the adhesive.
US10071328B2	Apparatus for separating particles from a fluid An apparatus for removing dirt from an airflow, the apparatus comprising an air inlet, an impeller for generating an airflow through the apparatus and for generating swirl within the airflow, the swirl throwing the dirt radially outwards and producing an outer dirty portion and an inner clean portion of airflow downstream of the impeller, and one or more splitters downstream of the impeller that bifurcate the airflow, separating the outer dirty portion from the inner clean portion.
US10071322B2	Hydrothermal cleanup process A high-rate hydrothermal cleanup (HCU) process and system is disclosed for the rapid hydrolysis of renewable oils and reduction of inorganic and organic contaminants, such as salts, minerals, metals, asphaltenes, polymers, and coke precursors in both renewable oils and petroleum fractions. The process and system is characterized by a very short residence time, high-temperature, high-pressure, turbulent flow, hydrothermal operation. The HCU and integrated vapor-liquid separation system and process results in high yields of oil product that contains significantly reduced concentrations of inorganic and organic contaminants. The process may be operated to produce a concentrated clean glycerin byproduct and short-chain and long-chain free fatty acid product streams. The integrated vapor-liquid separation system and process performs at near atmospheric pressure by taking advantage of the water employed in the cleanup process and the energy imparted by the HCU reactor and eliminates the need for vacuum distillation.
US10071308B2	System and method for capturing text for an online application A system and method for entering text within a video game application are described. For example, a system according to one embodiment of the invention comprises: a video game hosting service to execute a video game in response to user input; a client device to communicate with the video game hosting service over a first communication channel, wherein the client device has a first user input device communicatively coupled thereto, and wherein control signals for the video game are generated in response to input from the first user input device and transmitted from the client device to the video game hosting service over the first communication channel, the video game hosting service controlling a video game in response to receipt of the control signals; a display device communicatively coupled to the client device, the display device to display video of the video game; wherein the video game hosting service further includes program code to open a second communication channel to receive text input, the second communication channel being separate and independent from the first communication channel and usable by a data processing device capable of generating text input, wherein in response to receipt of text input over the second communication channel, the video game hosting service causes the text input to be displayed on the display device communicatively coupled to the client device.
US10071307B1	Virtual reality headset with retractable earphones A display housing for a head mounted image display apparatus, said display housing being configured to be mounted to the head of a user with a pair of optical visual units adapted to present a virtual image to the user and a pair of earphones for providing sound to the user, each of the earphones attached to a respective side of the housing via a respective wire. The display housing comprises a linear wire retraction assembly situated thereacross, the wire retraction assembly configured to control the amount that a respective wire is pulled from the housing to allow each earphone to be selectably movable between a first, retracted state and a second, extended state.
US10071305B2	Method and system for conducting and linking play of a lottery game with a televised game show simultaneously with a play-at-home version of the game show A system and method are provided for conducting a primary lottery game in conjunction with a televised game show and a play-at-home version of the show. In the primary lottery game, players purchase lottery tickets, with each ticket having a unique web code. Players of the primary lottery game become eligible to be a contestant in the show by accumulating a predefined set of game symbols in the lottery game. During broadcast of the game show, a plurality of game symbol codes are provided to at-home viewers of the show who are also players of the primary lottery game. The at-home viewers are able to access a website, enter the web code from their lottery ticket, enter one the game symbol codes broadcast with the game show, and play a web-based game to win a game symbol associated with the entered game symbol code.
US10071302B2	Folding longboard based on an indivisible flexible element A foldable longboard composed of a deck split in multiple sections connected on their lower surface with a folding assembly having an indivisible flexible element capable of bending near the interface between the different sections of the deck, allowing therefore said sections to be rotated in one direction to a folded position where the bottom surfaces of each section face each other, while inhibiting said sections to rotate in the other direction, against each other's top surface, when the longboard is in its elongated configuration.
US10071301B2	Event and sport performance methods and systems Methods and apparatus are disclosed for detecting and measuring performance characteristics and metrics of participants and vehicles. These performance characteristics and metrics include, but not are limited to, airtime, g-force, spin, rotation, drop distance, acceleration, and video and still images. These vehicles include, but are not limited to a snowboard, ski, skateboard, wakeboard, motorcycle, bicycle, ice skates and rollerblades. In one implementation, a camera provides near real-time images and video footage of a participant's actions on a vehicle which can be correlated with performance metrics. The camera may be located on the participant, the participant's vehicle or other equipment, or from some other observation point. The images recorded by the camera can be downloaded to a recording or other storage device to produce memorabilia (e.g., a CD ROM, or video cassette). If desired, the images can be sent in real-time through an event system and network (e.g., using a radio or other transmitter) to television, the Internet, and to other locations for producing the memorabilia or for providing images to television display devices, such as those located in a ski lodge for entertainment purposes or in a coach's or personal trainer's office for training purposes.
US10071300B2	Golf training aid A golf training aid is provided. The golf training aid includes a brace. The brace has a looped strap configured to wrap around and attach to an arm of a user. An elongated rod includes a top end and a bottom end. A first connector rod includes a first end and a second end. The first end is coupled to and extends laterally from the top end of the elongated rod and the second end is coupled to the brace. A second connector rod includes a first end and a second end. The first end is coupled to and extending laterally from the bottom end of the elongated rod. A clamp is coupled to the second end of the second connector rod and is configured to secure to a shaft of a golf club.
US10071298B1	Workout apparatus for simulating user movement patterns in bicycle sports A workout apparatus for use by a user to simulate core movement patterns of bike riding is provided. The workout apparatus includes a base deck disposed on a ground surface, a frame assembly pivotably mounted to the base deck and comprising a front portion and a rear portion, a handle bar coupled to the front portion of the frame assembly, and a pair of hydraulic damper units coupled to the frame assembly and base deck, the first hydraulic damper unit coupled to the base deck and front portion of the frame assembly, the second hydraulic damper unit coupled to the base deck and rear portion of the frame assembly. The user on the base deck grabs the handle bar to perform a pushing or pulling motion, thereby enabling the first hydraulic damper unit or second hydraulic damper unit to provide resistance to movement of the frame assembly.
US10071296B2	Instrumented, angle-adjustable batting tee An instrumented, swing path adjustable, angle-adjustable batting tee is disclosed that measures both a bat speed and a ball exit velocity as a hitter swings a bat and initiates contact with a ball positioned on the tee. A bat speed radar detector is coupled to the tee and positioned within proximity of the ball set on the tee so that the bat speed radar detector measures the bat speed upon the bat initiating contact with the ball. A ball exit velocity radar is coupled to the tee and positioned within proximity of a ball flight of the ball as it leaves the bat so that the ball exit velocity radar measures the ball exit velocity of the ball in-flight after contact between the bat and the ball. The ball flight is a path that the ball travels after contact between the bat and a baseball or softball.
US10071293B2	Golf putter heads According to various aspects, exemplary embodiments are disclosed of golf putter heads having customizable centers of gravity that are adjustable in three dimensions. Also disclosed are exemplary embodiments of methods of adjusting a center of gravity of a golf putter head.
US10071291B2	Golf irons with sealed undercut A golf club head includes a body, a first polymeric insert, and a second polymeric insert. The body includes a face, a sole, and a rear wall that collectively define an undercut volume. The first polymeric insert is provided within the undercut volume to define a sealed cavity within the undercut volume; and, the second polymeric insert is secured to the body and defines an open cavity extending from the rear wall toward the face.
US10071290B2	Golf club heads or other ball striking devices having distributed impact response A ball striking device, such as a golf club head, includes a face having a ball striking surface configured for striking a ball and a body connected to the face and extending rearwardly from the face. The body has an impact-influencing structure positioned adjacent at least one peripheral edge of the face. A majority of a force generated by impact with a ball is absorbed by the impact-influencing structure, and a majority of a response force generated by the head upon impact with the ball is generated by the impact-influencing structure. The face may have increased stiffness as compared to existing faces, and may include a stiffening structure to create the increased stiffness. In one embodiment, the face may have a stiffness proximate the geometric center that is from about 46,000 to 56,000 lb-in2.
US10071286B1	Systems and methods for determining and indicating a desired corrective change in exercise technique Systems and methods are for determining and indicating a desired corrective change in exercise technique to an operator and optionally for determining and indicating a correct or incorrect fit between an operator and an exercise equipment. The systems comprise an exercise apparatus that is engaged by an operator at least a first contact location; a first load sensor device that senses an operator-applied load amount at the first contact location; a controller that determines a desired corrective change in exercise technique and/or the correct or incorrect fit between the operator and the exercise equipment based at least upon the operator-applied load amount at the first contact location and a current body weight of the operator; and an indicator device that indicates the desired corrective change in exercise technique and/or correct or incorrect fit, for example to an operator or an instructor.
US10071284B1	Detecting and assessing vibrations caused by sporting equipment Disclosed are systems, devices, and methods for providing feedback regarding an impact between a sporting implement and a ball, an example system comprising a glove worn by a player, the glove including a sensor for detecting vibrations caused by an impact between the sporting implement and the ball and determining whether a level of the vibrations is within a predetermined range, and a speaker within audible range of the player, the speaker configured to emit an audible tone in response to receiving a signal from the sensor indicating that the level of the vibrations is determined to be within the predetermined range.
US10071281B1	Systems, devices, and methods for virtual and augmented reality sports training Disclosed are systems, devices, and methods for using virtual or augmented reality in sports training, an exemplary method including detecting a position of a real ball, determining a trajectory for a virtual ball, the trajectory intersecting with the detected position of the real ball, displaying, by a virtual or augmented reality display device, a virtual pitch of the virtual ball along the trajectory intersecting with the detected position of the real ball, detecting, by a sensor included in a glove worn by the player, vibrations caused by an impact between a bat held by the player and the real ball, determining whether a level of the vibrations is within a predetermined range, sending a signal, to a speaker, when the level of the vibrations is within the predetermined range, to cause the speaker to emit an audible tone, and emitting, by the speaker, the audible tone.
US10071279B2	Muscular strength assisting apparatuses and methods of controlling the same A muscular strength assisting apparatus may include: a wearing unit configured to enclose a part of a user's body; a tightening unit configured to pull the wearing unit in one or both directions; and/or a control unit configured to drive the tightening unit to tighten the part of the user's body on which the wearing unit is located, when it is determined that muscular contraction occurs at the part of the user's body on which the wearing unit is located. A method of controlling a muscular strength assisting apparatus may include: determining whether muscular contraction occurs at a part of a user's body that is enclosed by a wearing unit; and/or driving a tightening unit pulling the wearing unit in one direction or both directions to tighten the part of the user's body on which the wearing unit is located when it is determined that the muscular contraction occurs.
US10071273B2	Newtonian foam superconcentrate The invention provides an aqueous foaming Newtonian concentrate, an expanded foam composition and a process of forming a foam composition concentrate. The aqueous foaming concentrate includes a carbonized saccharide mixture, a surfactant, water and optionally further agents including cross-linking agents, thickeners, solvents, stabilizers, buffers, corrosion inhibitors and preservatives. Foaming concentrates of the present invention are free of fluorine and persistent organic pollutants and particularly suited for use in fire prevention, suppression and extinguishment, vapor suppression and wetting of surfaces at concentrations less than 1.3% by weight.
US10071270B2	Spray jet discharging device A spray jet discharging device of long range, whose function is based on the production of a powerful air stream with liquid droplets dispersed therein, the maximum velocity of the spray jet being at least 300 km/h. The air stream is produced by a centrifugal fan with a spiral housing (1). The device is mainly used for fire extinguishing. It may be mounted at fixed points or on land vehicles via a suitable support for the fan, which enables both rotation of the spray jet beam in the horizontal plane, and changing of its inclination angle in the vertical plane. It may be remotely controlled (10) or manually operated (60). There is also a version of the device for aerial fire-fighting operations (90), configured to be suspended from an aircraft, e.g. a helicopter, and a device for portable use (1 10), which can be carried by a fireman.
US10071268B2	Roof-mounted fall-arrest safety device A frame, one or more wheels rotationally attached to the frame, two or more end feet attached to opposite ends of the frame, one or more end safety tether attachments, and a flip-pole attachment. The frame straddles the roof peak so the end feet are stably positioned on opposite roof surfaces. The wheels enable the device, when flipped to its inverted position, to be rolled up and down the roof for installation and removal. The flip-pole attachment enables attachment of a flip pole for use in installing and removing the device from a ladder. And the end tether attachments enable workers to couple their safety tethers to the secured device so that if they fall their fall will be arrested for safety. In typical embodiments, an outrigger assembly is included with peak-mounting side feet for nesting on the roof peak and with side tether attachments for side attachment.
US10071267B2	Method, system and use for therapeutic ultrasound The described embodiments relate to methods, systems and uses for therapeutic ultrasound, and in particular, to methods, systems and uses for therapeutic ultrasound and contact lenses for treating or alleviating eye conditions. The described embodiments relate to methods, systems and uses that involve an ultrasound device configured for treatment of an eye condition and a contact lens protects ocular tissue of the eye and forms a chamber of air.
US10071264B2	Irradiation device using ionizing radiation, particularly for radiotherapy and/or radiobiology An irradiation device using ionizing radiation, particularly for radiation therapy and/or radiation biology, simultaneously includes: at least one unit (MER) for emitting ionizing radiation; at least one dose-monitoring unit (MCD); at least one unit for detecting an ionizing radiation dose (MDD); and at least one monitoring and control system (SCC). The units (MER, MDD, MCD) and the system (SCC) are also intelligently interconnected therebetween so as to engage with one another and form an intelligent monitoring and adjustment loop, such as to controllably, precisely and desirably produce strong doses of ionizing radiation of at least 0.01 Gy, having a precision within at least one 1μ Gy but preferably 1 n Gy, in strong dose rates up to 1000 Gy/s with power within a range of 1 to 50 Me V in very brief time intervals of at least 0.1 μs, preferably 1 ms.
US10071263B1	Pivoting multileaf collimator and method for large field coverage A radiation apparatus includes a source operable to generate a radiation beam, a multileaf collimator operable to shape of the radiation beam, and a pivoting mechanism configured to pivot the multileaf collimator about the source. The radiation apparatus may further include a rotating mechanism configured to rotate the multileaf collimator about an axis passing through the source and the multileaf collimator.
US10071261B2	Light therapy treatment A light therapy method, comprising identifying a pathological condition in a patient, selecting at least one light wavelength based on the identified pathological condition, and applying one or a combination of the selected light wavelengths to the patient using a light source.
US10071258B2	DNA oxidative damage repairing device and application method thereof Disclosed are a DNA oxidative damage repairing device and an application method thereof. The device is composed of an electrons emitting assembly, an electrons emitting electrode, a control system, a power source, a support and the like. The device emits electrons to a space in a certain range, negatively charged nano particles with certain density are formed in the space, the space is sterilized, and various hazardous substances in suspension space are eliminated. The negatively charged nano particles entering a body through a respiratory system release electrons carried by the particles, electrons lost due to oxidative damage are replenished to all parts of the body, and dormant state genes can also be repaired and activated. The two-way regulations function can play a role in broad spectrum medical treatment, so that diseases that cannot be cured through drugs easily are present are cured. The device has an obvious curative effect on diseases caused by immune function deficiencies, diseases of a respiratory system, various wounds, diseases caused by drug addiction treatment and the like. The method is combined with correct and effective using of suppressing drugs and accurate using of traditional Chinese medicine, and accordingly a novel hopeful therapeutic scheme of treating AIDS, cancers and various genetic diseases before histone codes are deciphered can be provided.
US10071257B2	Method for low-voltage termination of cardiac arrhythmias by effectively unpinning anatomical reentries A method for extinguishing a cardiac arrhythmia utilizes destructive interference of the passing of the reentry wave tip of an anatomical reentry through a depolarized region created by a relatively low voltage electric field in such a way as to effectively unpin the anatomical reentry. Preferably, the relatively low voltage electric field is defined by at least one unpinning shock(s) that are lower than an expected lower limit of vulnerability as established, for example, by a defibrillation threshold test. By understanding the physics of the electric field distribution between cardiac cells, the method permits the delivery of an electric field sufficient to unpin the core of the anatomical reentry, whether the precise or estimated location of the reentry is known or unknown and without the risk of inducting ventricular fibrillation. A number of embodiments for performing the method are disclosed.
US10071254B2	Optically based devices, systems, and methods for neuromodulation stimulation and monitoring Devices, systems, and methods for neuromodulation are provided. For example, a neuromodulation system is disclosed that comprises an implantable neuromodulation module having a photodiode configured to generate electrical current in response to receiving light from an optical fiber; an optical transceiver; and at least one electrode configured to provide electrical stimulation to a nerve utilizing the electrical current generated by the photodiode. As another example, a method of neuromodulation is disclosed that comprises receiving light at a photodiode of a neuromodulation module and generating electrical current in response to receiving the light; and providing, via at least one electrode of the module positioned within the patient, electrical stimulation to a nerve of the patient utilizing the electrical current generated by the photodiode.
US10071252B2	Methods and systems for wireless communication with a subcutaneous medical device An exemplary subcutaneous medical device implanted within a patient uses a coil-less magnetic field sensor included within the subcutaneous medical device to detect a toggling sequence between a presence and an absence of an externally-generated static magnetic field. The toggling sequence is representative of a digital data stream according to a digital wireless communication protocol. The subcutaneous medical device identifies, based on the detected toggling sequence and in accordance with the digital wireless communication protocol, a multi-bit command encoded within the digital data stream represented by the toggling sequence. The subcutaneous medical device further performs, in response to the identifying of the multi-bit command, an action associated with the multi-bit command. Corresponding methods and a corresponding external controller are also disclosed.
US10071251B2	Systems and methods for wireless control of noninvasive electrotherapy Methods and devices for providing noninvasive electrotherapy and electrical stimulation are described herein. In one aspect, a device for noninvasive electrotherapy includes wireless communication circuitry configured to receive pulse generation control signals wirelessly transmitted from a computing device. The device can include pulse generation circuitry configured to deliver electrical waveforms according to instructions encoded in the pulse generation control signals. The computing device can include a cellular telephone device, a portable media player, a personal digital assistant, a tablet computer, or an internet access device.
US10071246B2	Selective stimulation with cochlear implants A signal processing arrangement generates electrode stimulation signals to stimulation contacts in a cochlear implant electrode array. A signal filter bank transforms an input sound signal into band pass signals, which each represent an associated frequency band of audio frequencies. A signal processing module processes the band pass signals in a sequence of sampling time frames, wherein for each time frame, the processing includes performing a spectral feature analysis of the band pass signals, and dynamically assigning a stimulation focus pattern to one or more of the band pass signals based on the spectral feature analysis. A stimulation coding module is configured to code the processed band pass signals for each time frame to produce the electrode stimulation signals for delivery by the stimulation contacts to a region of adjacent auditory neural tissues.
US10071244B2	Thoracoscopic electroporation device with a suction head and with needle electrodes A thoracoscopic electroporation device for carrying out electroporation on tissue includes a suction head and a plurality of needle electrodes. The needle electrodes include a central needle providing a first electrode and a plurality of second needles which are spaced-apart around the periphery of the suction head. The electrodes are movable from a retracted configuration to a deployed configuration and in the deployed configuration the needles extend from the suction head. The suction head has a retracted delivery configuration and an expanded deployed configuration. The suction head includes a suitable flexible material for biasing the suction head into the expanded deployed configuration. The suction head has channels for the needles and the needles are movable through the channels from the retracted to the deployed configuration. In the deployed configuration, the central first needle extends beyond the peripheral needles.
US10071239B2	Architectures for multi-electrode implantable stimulator devices having minimal numbers of decoupling capacitors Architectures for implantable stimulators having N electrodes are disclosed. The architectures contains X current sources, or DACs. In a single anode/multiple cathode design, one of the electrodes is designated as the anode, and up to X of the electrodes can be designated as cathodes and independently controlled by one of the X DACs, allowing complex patient therapy and current steering between electrodes. The design uses at least X decoupling capacitors: X capacitors in the X cathode paths, or one in the anode path and X−1 in the X cathode paths. In a multiple anode/multiple cathode design having X DACs, a total of X−1 decoupling capacitors are needed. Because the number of DACs X can typically be much less than the total number of electrodes (N), these architectures minimize the number of decoupling capacitors which saves space, and ensures no DC current injection even during current steering.
US10071237B2	Systems and methods for therapeutic electrical stimulation In various embodiments, the invention disclosed herein provides systems, devices and methods for providing electrical stimulation to a patient. An electrical mechanical interconnection is provided to facilitate user friendly systems and devices. Exemplary therapeutic electrical stimulation devices include a shoe connected mechanically and electrically to a conductor that provides signals for electrical stimulation.
US10071236B2	Total isolation diverter valve The invention describes a total isolation diverter valve comprising a valve body whereon a main inlet conduit for inletting a fluid, a first outlet conduit for outletting the fluid and at least one second outlet conduit for outletting the fluid are obtained. The first outlet conduit for outletting the fluid is provided with a first fluid adhesion inner surface and the second fluid outlet conduit is provided with a second fluid adhesion inner surface. Between the main fluid inlet conduit and the two fluid outlet conduits a connection channel is interposed. On the connection channel at least one device for perturbing at least one of the first fluid adhesion inner surface and the second fluid adhesion inner surface is provided. The perturbation device is configured so as to cause a deviation of the fluid flow from the first fluid outlet conduit to the second fluid outlet conduit or vice-versa by exploiting a physical effect called Coand{hacek over (a)} effect. The perturbation device comprises at least one perturbation orifice, which faces the first fluid adhesion inner surface, and at least one opening/closing element, configured for opening and sealingly closing a respective perturbation orifice.
US10071228B2	Preformed stylet for guiding a lead to contact the septum Preformed guiding stylet for introducing a septal lead in contact with the septum or other intra-corporal device in contact with body tissue. This stylet includes a flexible wire to be introduced by its distal end in a central lumen of the lead, and a control handle. The wire is elastically deformable in bending and has sufficient rigidity in torsion to enable transmission by the handle rotation of a rotational movement over the entire length of the wire. Unstressed, the wire comprises successively in its distal part a first curvilinear portion a first straight portion a second curvilinear portion and optionally a second straight portion. The first and second curvilinear portions extend in respective planes making an angle between them defining a dihedral which axis comprises the first straight portion. The total length of the first curvilinear portion coincides with the anatomical curvature of the venous system.
US10071227B2	Gas-elimination patient access device Disclosed are devices, systems, and methods for providing access to a patient. The patient access device comprises a proximal end, a distal end and a lumen therethrough. The patient access device further comprises a hollow shaft, an input port and a liquid supply port. At least a portion of the lumen passes through the shaft. The input port is coupled to the lumen, and the lumen and the input port are constructed and arranged to receive an elongate probe. The liquid supply port is in fluid communication with the lumen. The patient access is constructed and arranged to reduce gas from exiting the distal end while a portion of the elongate probe is positioned in the patient access device.
US10071225B2	Coaxial bi-directional catheter A deflectable catheter including an outer member having a proximal portion and a distal portion, an elongated column member extending distally from the outer member and an inner member positioned coaxial with the outer member and attached to the column member. The inner member extends distally of the outer member and has a distal tip portion. A reinforcement member is positioned over the column member to restrict axial movement of the column member such that when one of the inner member or outer member is moved with respect to the other, axial compression of the column member is restricted by the reinforcement member causing the distal tip portion of the inner member to deflect laterally.
US10071222B2	Electrode catheters and methods for making them Catheters, sheaths, or other tubular devices are provided that include a proximal end, a distal end sized for introduction into a patient's body, and a steerable distal portion carrying a plurality of electrodes. The tubular device includes a primary lumen extending between the proximal and distal ends; a steering element lumen adjacent the primary lumen; a plurality of wires extending proximally from the electrodes, and reinforcement members including windings extending helically along at least the distal portion, at least some of the windings passing between the primary and steering element lumens and wires, and at least some of the windings surrounding the primary lumen and one or both of the steering element lumen and the wires. In one embodiment, a steering element is slidably disposed within the auxiliary lumen. Apparatus and methods for making such tubular devices are also provided.
US10071219B1	Anesthetic tank, and system for preventing erroneous anesthetic injection An anesthetic tank includes an insertion mouth for inserting an injection adapter of an anesthetic container, and a storage portion communicating with the insertion mouth. A volatile anesthetic inside of the anesthetic container is injected into the storage portion. An identifying member is arranged on the outside of the insertion mouth and is rotatable around the center axis of the insertion mouth. The identifying member has key groove formed in the internal surface of an insertion hole for inserting the injection adapter. The key groove are used for identifying the type of the volatile anesthetic in collaboration with keys formed in the injection adapter. A cover member has an opening formed in the position facing the insertion mouth and the insertion hole and presses the peripheral part of the identifying member.
US10071215B2	Medical device system including guide rod illumination A medical device system is provided. The medical device system includes a positioning apparatus having a body section and an upper section, the upper section slidably coupled to the body section such that the upper section slidably moves relative to the body section. The medical device also includes a flexible guide rod extending through the positioning apparatus and configured to be inserted into a passage of a respiratory system of a subject. The flexible guide rod includes a visible light emitter configured to emit visible light within the passage of the respiratory system and is visible outside the subject.
US10071202B2	Medical device data integration apparatus and methods Methods, systems, and apparatuses integrating medical device data are disclosed. In an example embodiment, a vital sign monitor apparatus includes a renal failure therapy interface configured to receive a renal failure therapy parameter from a renal failure therapy machine performing a renal therapy treatment on a patient and an infusion pump interface configured to receive an infusion parameter from an infusion pump performing an infusion treatment for the same patient. The apparatus also includes a vital sign monitor engine configured to display, within a combination user interface of a vital sign monitor, the renal failure therapy parameter within a renal failure therapy timeline, and the infusion parameter within an infusion timeline that is aligned with the renal failure therapy timeline.
US10071199B2	Multi-stage biodegradable drug delivery platform Embodiments of the invention provide multi-stage biodegradable drug delivery platforms and methods for the subcutaneous delivery of therapeutic agents (TA). Embodiments of the platform may be configured to subcutaneously deliver a first dose of a first TA which is absorbed into the body and/or blood stream (BBS) to produce a first therapeutic effect for a first selectable time period (STP), and subsequently after a second STP, deliver a second dose of a second TA which is absorbed into the BBS to produce a second therapeutic effect for a third STP. An embodiment of the platform may comprise a body having a tissue-penetrating end, a primary cavity having a first TA dose and a shell having a secondary cavity having a second TA dose. The first TA dose is released after the first STP and the second TA dose is released after the second STP by biodegradation of the shell.
US10071197B2	Therapy system including multiple posture sensors Posture-responsive therapy is delivered by the medical system based on posture state input from only one of multiple posture sensors at any given time. An example implantable medical system includes a first posture sensor and a second sensor. A processor controls therapy delivery to the patient based on at least one of a patient posture state or a patient activity level determined based on input from only one of the first or second posture sensors. In some examples, one of multiple posture sensors of an implantable posture-responsive medical system is used to automatically reorient another posture sensor (of the system), which has become disoriented. The disoriented posture sensor may be automatically reoriented for one or more posture states at a time.
US10071192B2	Catheter pump assembly including a stator A catheter pump assembly is provided that includes a proximal a distal portion, a catheter body, an impeller, and a flow modifying structure. The catheter body has a lumen that extends along a longitudinal axis between the proximal and distal portions. The impeller is disposed at the distal portion. The impeller includes a blade with a trailing edge. The flow modifying structure is disposed downstream of the impeller. The flow modifying structure has a plurality of blades having a leading edge substantially parallel to and in close proximity to the trailing edge of the blade of the impeller and an expanse extending downstream from the leading edge. In some embodiments, the expanse has a first region with higher curvature and a second region with lower curvature. The first region is between the leading edge and the second region.
US10071189B2	Medical apparatus with lubricity and manufacturing method of same The present disclosure provides a medical instrument with a coating that provides excellent lubricity when wet. The medical instrument possesses a coating including a wet lubricating film with high peel durability and anti-eluting properties. In embodiments, an intermediate film made of bisphenol A type epoxy resin is coated on a base material of a medical instrument made of metal, and a wet lubricant coating produced by alkaline processing of a polymer alloy containing a methyl vinyl ether maleic anhydride copolymer and a polyether block amide is then applied thereto. Methods for making these medical instruments are also provided.
US10071187B2	Methods, substrates, and systems useful for cell seeding of medical grafts Described are methods, cell growth substrates, and devices that are useful in preparing cell-containing graft materials for administration to patients. Tubular passages can be defined in cell growth substrates to promote distribution of cells into the substrates. Also described are methods and devices for preparing cell-seeded graft compositions, methods and devices for preconditioning cell growth substrates prior to application of cells, and cell seeded grafts having novel substrates, and uses thereof.
US10071186B2	Glycosaminoglycan and synthetic polymer material for blood-contacting applications Provided herein is a composite, comprising: a polymer host selected from the group consisting of low-density polyethylene (LDPE), linear low-density polyethylene (LLDPE), polyethylene terephthalate (PET), polytetrafluoroethylene (PTFE), and polypropylene (PP), polyurethane, polycaprolactone (PCL), polydimethylsiloxane (PDMS), polymethylmethacrylate (PMMA), and polyoxymethylene (POM); and a guest molecule comprising hyaluronic acid; wherein the guest molecule is disposed within the polymer host, and wherein the guest molecule is covalently bonded to at least one other guest molecule. Also provided herein are methods for forming the composite, and blood-contracting devices made from the composite, such as heart valves and vascular grafts.
US10071185B2	Compartmental extract compositions for tissue engineering The present invention concerns biologically-active cell-free scaffolds composed of extracts of cellular and/or extracellular compartments for use in tissue regeneration. The present invention also contemplates the novel concept of redesigning the biological scaffold by seeding cells thereon followed by cell elimination. Cells are seeded on the scaffold for a period of time during which a dynamic interaction occurs between the scaffold and the seeded cells, resulting in reshaping of the scaffold architecture and integration of newly synthesized matrix elements. Redesigning may improve the physical and biological characteristics of the scaffold, and also improve the matching of the scaffold to treat a specific target tissue or a specific patient, by seeding tissue-specific cells or by seeding cells which are autologous to a patient, respectively.
US10071183B2	Amphiphilic linear peptide/peptoid and hydrogel comprising the same The present invention provides an amphiphilic linear peptide and/or peptoid as well as a hy-drogel that includes the amphiphilic linear peptide/peptoid. The amphiphilic linear pep-tide/peptoid is capable of forming, a hydrogel. These peptides/peptoids include short amphi-philic sequences with a hydrophobic portion of aliphatic amino acids and at least one acidic, neutral, or basic polar amino acid. The amphiphilic linear peptide/peptoid is build up of non repetitive aliphatic amino acids, which may be in the L- or D-form. A plurality of such pep-tides/peptoids assembles to supramolecular helical fibers and forms peptide hydrogels after assembly: A corresponding hydrogel is formed in aqueous solutions at physiological pH and is thus useful for inter alia cell culture, tissue engineering, and drug release. Such hydrogels which are rigid, biocompatible and entrapping up to 99.9% of water are also well suited for applications utilizing electronic devices.
US10071179B2	Device for evaporating volatile fluid An assembly adapted to evaporate a volatile fluid having a device and a refill which are detachable from one another: the device includes a magnetic induction coil configured to operate with an alternating current passed therethrough at a frequency of between substantially 20 KHz to substantially 500 KHz and a volatile fluid transport part receiving area containing at least one piece of heat-conducting, non-magnetic metal foil and/or deposited heat-conducting, non-magnetic metal; and the refill includes a reservoir for the volatile fluid, a volatile fluid transport part to draw the fluid from the reservoir, and at least one magnetic susceptor having a coercivity of substantially 50 ampere/meter (HC) to substantially 1500 ampere/meter (HC). arranged to heat the wick predominately by magnetic hysteresis when an alternating current is passed through the induction coil, such that when the refill is attached to the device at least one magnetic susceptor is at least partially located within the volatile fluid transport part receiving area. Refills, devices and methods of operation are also described.
US10071178B2	Sealable decontamination holding vessel for isolating contaminated items A sealable decontamination holding vessel configured to isolate contaminated items being held therein until safe opening of the vessel occurs during a high pressure and temperature sterilization cycle in an autoclave. The vessel basically includes an outer container, a perforated inner receptacle, containment bag and cover lid. The inner receptacle fits into the outer container. The containment bag fits within the inner receptacle with an open end of the bag draped over an open top lip of the inner receptacle. The cover lid is secured and sealed over the open top of the outer container. Patches of self-adhering sealing materials are placed over vent holes in the outer container and cover lid so as to seal the same until they unseal in response to contact with sterilizing steam in the autoclave allowing flow of the steam through the outer container into the inner receptacle and containment bag.
US10071173B2	Fiducial marker for use in stereotactic radiosurgery and process of production Composition in the form of a shaped device, for use as a fiducial marker in tissues in the animal body, in radiotherapy and/or radiosurgery, characterized in that it comprises:—a core consisting of a colloidal dispersion of metal nanoparticles and/or oxides or metal salts having X-ray-contrast properties, where said nanoparticles are stabilized with surfactants, polymers or capping agents in a liquid vehicle, and—a polymeric casing that encapsulates the core, said device having a minimum size of not less than 500 microns and a maximum size not greater than 3000 microns.
US10071170B2	Antibody-drug conjugate having improved stability and use thereof The present invention relates to an antibody-drug conjugate comprising a drug conjugated to an antibody, a preparation method thereof and the use thereof.
US10071166B2	Protein complex using an immunoglobulin fragment and method for the preparation thereof Disclosed are a protein conjugate with improved in vivo duration and stability and the use thereof. The protein conjugate includes a physiologically active polypeptide, a non-peptide polymer and an immunoglobulin Fc fragment. Since the three components are covalently linked, the protein conjugate has extended in vivo duration and enhanced stability for the physiologically active polypeptide. The protein conjugate maintains the in vivo activity at relatively high levels and remarkably increases the serum half-life for the physiologically active polypeptide, with less risk of inducing undesirable immune responses. Thus, the protein conjugate is useful for developing long-acting formulations of various polypeptide drugs.
US10071165B2	Protein-cell conjugate, preparation method and use thereof The present invention pertains to immunology, biomedicine field, specifically relates to a protein-cell conjugate, which is characterized in that the protein and the cell are coupled via a bifunctional cross-linking agent. The present invention further relates to a preparation method and uses of the protein-cell conjugate. The protein-cell conjugate of the present invention can be used for prevention or treatment of many diseases, such as malignant tumors, infectious diseases and autoimmune diseases.
US10071161B2	Methods and materials for therapeutic delivery Method for preparing a supramolecular therapeutic agent delivery assembly are provided. A carbonate-containing precursor, a functionalized aliphatic precursor, and an aromatic diamine precursor may be combined to form an amphiphilic block co-polymer. The block co-polymer undergo a cross-linking polymerization process and a therapeutic agent may be incorporated into the resulting supramolecular assembly. The supramolecular assembly may comprise HT, PHT, HA, and/or PHA materials.
US10071160B2	Derivatized hyperbranched polyglycerols Herein are provided derivatized hyperbranched polyglycerols (“dHPGs”). The dHPG comprises a core comprising a hyperbranched polyglycerol derivatized with C1C20 alkyl chains and a shell comprising at least one hydrophilic substituent bound to hydroxyl groups of the core, wherein the hyperbranched polyglycerol comprises from about 1 to about 200 moles of the at least one hydrophilic substituent. The dHPGs are for use as agents for the delivery of a drug or other biologically active moiety to the urinary tract, the digestive tract, the airways, the vaginal cavity and cervix and the peritoneal cavity to treat indications such as cancer, which may be useful in the treatment of or the manufacture of a medicament, in the preparation, of a pharmaceutical composition for the treatment of cancer, as a pre-treatment or co-treatment to improve drug uptake in a tissue. Furthermore, there are provided methods of making dHPGs.
US10071155B2	Nasal mucosal vaccine composition The present invention provides a nasal mucosal vaccine composition which is safe, useful as a preventive or therapeutic agent for infectious diseases or cancers, and capable of inducing systemic immune responses and mucosal immune responses effectively. The present invention provides a nasal mucosal vaccine composition to be administered to a human or animal nasal mucous membrane, the nasal mucosal vaccine composition containing at least one antigen excluding antigens derived from influenza viruses; and as an adjuvant, a lipopolysaccharide derived from at least one gram-negative bacterium selected from the group consisting of Serratia, Leclercia, Rahnella, Acidicaldus, Acidiphilium, Acidisphaera, Acidocella, Acidomonas, Asaia, Belnapia, Craurococcus, Gluconacetobacter, Gluconobacter, Kozakia, Leahibacter, Muricoccus, Neoasaia, Oleomonas, Paracraurococcus, Rhodopila, Roseococcus, Rubritepida, Saccharibacter, Stella, Swaminathania, Teichococcus, Zavarzinia, Pseudomonas, Achromobacter, Bacillus, Methanoculleus, Methanosarcina, Clostridium, Micrococcus, Flavobacterium, Pantoea, Acetobacter, Zymomonas, Xanthomonas, and Enterobacter, or a salt thereof.
US10071153B2	Therapeutic peptides and vaccines Compositions are disclosed that induce broadly HIV therapeutic and vaccine inducing antibodies against diverse HIV clades and relate to the ability to identify HIV gp120-derived short peptide sequence immunogens and various therapeutic compositions made from the identified peptides which compose CCR5 binding sites. Also disclosed are methods of selecting peptide sequences that are likely candidates for drugs which will offer effective treatment in such areas as Alzheimer's disease, psoriasis, multiple sclerosis and other diseases associated with the human inflammatory cascade as well as related retroviruses such as HTLV-1, the cause of tropical spastic paraparesis.
US10071149B2	Temperature sensitive multivalent Bordetella avium vaccines The present invention is related to various vaccine compositions against Bordetella avium and methods for preparing and administering the various vaccine compositions. The present invention is related to multivalent vaccines compositions such as bivalent or trivalent vaccines for inoculating turkeys against from Bordetella avium rhinotracheitis or coryza due to Bordetella avium infection as well as methods of preparing and administering the multivalent vaccine compositions.
US10071148B2	Immunotherapy against several tumors, such as lung cancer, including NSCLC The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to more than 70 novel peptide sequences and their variants derived from HLA class I and HLA class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
US10071144B2	Cell therapy for the treatment of neurodegeneration Methods are described for the isolation and selection of a heterogeneous bone marrow cell population, called NCS-01, that is effective at treating neurodegeneration. For example, NCS-01 cells are shown to treat neurodegeneration caused by ischemia. In vivo studies demonstrate that selected NCS-01 cell populations treat neurodegeneration in a standard rat middle cerebral artery occlusion (MCAO) animal model under conditions of transient or permanent total arterial occlusion. These studies also disclose that when the neurodegeneration is caused by ischemic stroke, combining the administration of a selected NCS-01 cell population with thrombolytic agents and/or mechanical methods of clot removal leads to a decrease in the volume of infarction caused by acute onset neurodegeneration. The disclosed cell therapy promises to make a significant clinical impact on patient survival after stroke.
US10071143B1	Methods for non-surgical treatment of carpal tunnel syndrome Provided is a non-surgical method of treatment of carpal tunnel syndrome by administering an effective amount of purified collagenase I and II by injection onto a transverse carpal ligament, without penetrating the transverse carpal ligament. The purified collagenase I and II are obtained from Clostridium histolyticum, and the effective amount is a dose comprising a concentration of approximately 0.29 mg of the purified collagenase I and II to one ml diluent.
US10071140B2	Amylin analogues The present invention relates to amylin analogues and to their use in the treatment or prevention of a variety of diseases, conditions or disorders, including obesity, excess food intake and associated metabolic diseases such as diabetes. The analogues have good physical and chemical stability, good solubility, and a long duration of action, and are well suited for use in the form of a liquid formulation.
US10071133B2	Method for destroying exosomes, kit for destroying exosomes, and method for isolating exosomes derived from normal cells A method for destroying exosomes of the present invention includes a step of preparing an antimicrobial peptide; and a step of allowing the antimicrobial peptide to coexist with an exosome to destroy the exosome.
US10071129B2	Method for identifying bromodomain inhibitors Disclosed herein are methods and compositions useful for inhibiting interaction between a bromodomain protein and an immunoglobulin (Ig) regulatory element. The methods and compositions are particularly useful for downregulating expression of an oncogene translocated with an Ig locus, as well as for treating a cancer (e.g., hematological malignancy) characterized by increased expression of an oncogene which is translocated with an Ig locus. Also disclosed herein are methods and assays for identifying agents that interfere with binding of bromodomain proteins to Ig regulatory elements, as well as methods and assays for identifying inhibitors of bromodomain.
US10071123B2	Treatment of pulmonary arterial hypertension with mesenchymal stem cells The application is directed to a method for treating or preventing vasculopathy comprising administrating to a subject in need thereof a pharmaceutical composition comprising mesenchymal precursor cells (MPCs) and a prostacyclin. Also provided a method for treating or preventing vasculopathy in a subject in need thereof, comprising administering to the subject a prostacyclin and a mesenchymal stem cell (MSC) or a MSC-conditioned culture medium or administering to the subject a MSC or a MSC-conditioned culture medium that has treated with prostacyclin. Pharmaceutical compositions suitable for such treatments are also provided.
US10071121B2	Cardiac, mesenchymal and endothelial progenitor cell (CPC) chimeras and methods for making and using them In alternative embodiments, provided are chimeric cells, which in alternative embodiments are the so-called “cardiochimeras”, and methods for making and using them. In alternative embodiments, exemplary chimeric cells as provided herein comprise a cardiac stem cell of cardiac origin or a cardiac progenitor cell fused to either a mesenchymal progenitor cell or mesenchymal stem cell, an endothelial progenitor cell or endothelial stem cell, or a cardiac stem cell or a cardiac progenitor cell. In alternative embodiments, the chimeric cells as provided herein comprise an endothelial progenitor cell, which may or may not be of cardiac origin, fused to either a mesenchymal progenitor cell or mesenchymal stem cell, an endothelial progenitor cell or endothelial stem cell, or a cardiac stem cell or a cardiac progenitor cell. In alternative embodiments, methods for making chimeric cells as provided herein further comprise selecting a cell fusion product comprising a viable chimera of the fused cells. In alternative embodiments, methods for making chimeric cells as provided herein comprise use of any known cell fusion technique, for example, using a Sendai virus, such as a Sendai virus Hemagglutinating Virus of Japan Envelope (HVJ-E), a polyethylene glycol, liposomes or lipids, a fusion protein, electrofusion and/or equivalents thereof. In alternative embodiments, provided are cell lines, chimera (chimeric) cell lines or chromosomally-stable chimera cell lines, derived or made from chimeric cells as provided herein. In alternative embodiments, provided are methods for inducing cardiogenesis in a mammalian heart comprising administration to an individual in need thereof (for example, a human), chimeric cells as provided herein, or a cell line, a chimera cell line or a chromosomally-stable chimera as provided herein. In alternative embodiments, provided are methods for treating or ameliorating a heart injury, a congenital or genetic heart defect, or a heart dysfunction, comprising administration to an individual in need thereof (for example, a human), chimeric cells as provided herein, or a cell line, a chimera cell line or a chromosomally-stable chimera as provided herein.
US10071118B2	Compositions and methods for treating peritoneal cancers The present disclosure provides compositions and methods for treating a peritoneal cancer in a subject. The methods include administering a T cell which is genetically modified to express a chimeric T cell receptor protein. The chimeric T cell receptor protein may include a T cell receptor signaling domain fused to the tumor associated antigen-binding fragment of an antibody or a T cell receptor signaling domain fused to a naturally occurring ligand which specifically binds to a tumor cell surface protein. The compositions and methods disclosed herein are therapeutically effective to reduce, for example, tumor burden, abdominal ascites, peritoneal mucin, or serum tumor marker levels.
US10071116B2	Method for manufacturing hydrogen-saturated deuterium-depleted water The present invention relatives to a method for manufacturing hydrogen-saturated deuterium-depleted water, comprising (a) providing a distilled or mineral water; (b) providing a hydrogen storage apparatus for providing a high purity hydrogen; (c) controlling a pressure of hydrogen gas between 3˜8 bar at a working environment temperature of 10˜28° C.; (d) controlling a flow velocity of hydrogen gas between 3˜5 L/min and inletting hydrogen into the distilled or mineral water to produce a pressure difference to replace deuterium from the distilled water; and (e) controlling a working time between 30˜90 mins to produce a hydrogen-saturated deuterium-depleted water. Therefore, a method for manufacturing hydrogen-saturated deuterium-depleted water with low consuming energy and low production cost is provided.
US10071115B2	Method of promoting wound healing Disclosed is a method of promoting wound healing or wound closure. The method comprises administration of a miR-198 inhibitor and/or a follistatin-like-1 (FSTL1) polypeptide. Also disclosed are method of treating chronic cutaneous wounds, method of identifying a non-healing wound, use and a pharmaceutical composition comprising a miR-198 inhibitor and/or a follistatin-like-1 (FSTL1) polypeptide.
US10071109B2	Predictive biomarker for hypoxia-activated prodrug therapy CYP2W1 levels are predictive of the probability that a cancer patient will respond favorably to cancer therapy involving administration of a hypoxia-activated achiral phosphoramidate mustards.
US10071104B2	Pharmaceutical compositions containing testosterone and an aromatase inhibitor An implant comprising testosterone or an ester thereof and an aromatase inhibitor; the aromatase inhibitor may be selected from the group consisting of anastrozole, letrozole, and exemestane. In one embodiment the implant is a sustained release, subcutaneous implant. Also disclosed are therapies for patients with symptoms of relative androgen deficiency, breast cancer survivors and other therapies in which testosterone is indicated but elevated estradiol levels are avoided.
US10071103B2	Treatments for resistant acne The present disclosure relates generally to novel molecules, compositions, and formulations for treatment of bacterial infections in general and more specifically to bacterial infections with antibiotic resistant pathogens.
US10071101B2	Use of cinnabarinic acid as a modulator of immune response in autoimmune disorders The present invention provides compounds and methods for preventing and treating an immune disorder in a subject.
US10071095B2	1,2,4-triazolo [4,3-A] pyridine derivatives and their use for the treatment of neurological and psychiatric disorders The present invention relates to methods of treating various central nervous system disorders using novel triazolo[4,3-a]pyridine derivatives of Formula (I) wherein all radicals are as defined in the claims. The compounds according to the invention are positive allosteric modulators of the metabotropic glutamate receptor subtype 2 (“mGluR2”), which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, and to the use of such compounds for the prevention or treatment of neurological and psychiatric disorders and diseases in which mGluR2 is involved.
US10071092B2	Polymorphic forms of vortioxetine and its pharmaceutically acceptable salts The present invention provides polymorphic forms of Vortioxetine of and its pharmaceutically acceptable salts. Specifically the present invention relates to the novel crystalline forms of Vortioxetine or its pharmaceutically acceptable salts. Moreover, the present invention also provides an amorphous form of Vortioxetine hydrobromide and a stable amorphous co-precipitate of Vortioxetine hydrobromide with pharmaceutically acceptable excipients.
US10071089B2	Combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation The present invention is concerned with an oral pharmaceutical dosage form comprising oxycodone or a pharmaceutically acceptable salt thereof and naloxone or a pharmaceutically acceptable salt thereof for use in the treatment of pain in patients suffering from i) pain and at least one further disease ii), wherein said at least one further disease ii) results in intestinal dysbiosis, or for use in the treatment of pain in patients suffering from i) pain and at least one further disease iii), wherein said at least one further disease iii) increases the risk for intestinal bacterial translocation and thus for peritonitis, SIRS and/or sepsis.
US10071088B2	Anti-nausea drug combinations Methods and compositions are disclosed for reducing Post Operative Nausea and/or Vomiting (PONV) in a human patient in need of general anesthesia. Such methods may include scheduling surgery for the human patient and administering to the patient one or more series of prescribed medicines days during a regimen preceding general anesthesia to condition receptors involved in the nausea and/or vomiting reflex.
US10071084B2	Nanoparticle, method of preparating the same, and use of the nanoparticle A nanoparticle including a hydrophobic active ingredient and a polypeptide, as well as a liposome including the nanoparticle and methods of making and using the nanoparticle.
US10071083B2	Use of gaboxadol in the treatment of tinnitus Methods of treating tinnitus with gaboxadol or a pharmaceutically acceptable salt thereof are provided. Also provided are therapeutic compositions that may be used to improve one or more symptoms of tinnitus. Methods of treating acute sensorineural hearing loss or Meniere's disease with gaboxadol or a pharmaceutically acceptable salt thereof are provided. Also provided are therapeutic compositions that may be used to improve one or more symptoms of acute sensorineural hearing loss or Meniere's disease.
US10071080B2	MIF inhibitors for the acute or chronic treatment of pulmonary hypertension The present invention relates to the use of compounds of general Formula I and pharmaceutically acceptable enantiomers, salts or solvates thereof, for treating pulmonary hypertension in a subject.
US10071073B2	Compositions containing as the active ingredient components from Salvia sclarea seed The present invention concerns a food supplement comprising Salvia sclarea seeds, or flour, oil or pulp or extracts obtained from the seeds as well as finished food products comprising the food supplement. The present invention further concerns a nutraceutical or cosmetic preparation comprising as an active ingredient Salvia sclarea seeds, or flour, oil or pulp or extracts obtained from the seeds.
US10071072B2	Method for treating neurotrauma The invention relates to a composition comprising:i) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof;ii) a lipid fraction comprising at least one of docosahexaenoic acid (22:6; DHA), eicosapentaenoic acid (20:5; EPA) and docosapentaenoic acid (22:5; DPA), or esters thereof, in which the lipid fraction comprises less than 2 weight % of α-linolenic acid (ALA), calculated on the weight of all fatty acids; iii) choline, or salts or esters thereof; for use in the prevention or treatment of neurotrauma, traumatic brain injury, cerebral palsy and spinal cord injury.
US10071066B2	Method of treating cancer using selective estrogen receptor modulators Disclosed herein are methods of treating subjects suffering from estrogen receptor positive cancer of the brain by administering a selective estrogen receptor degrader (SERM). Also disclosed are methods of treating a cancer that is resistant to an estrogen receptor modulator by administering a SERM.
US10071064B2	Tincture for infusing flavonoids and methods of use Methods and formulations for batch-mixing flavonoid tinctures and infusing the flavonoid batch-mixed tincture into a food, beverage, cosmetic or drug products with minimal or no effect on the alcohol by volume of the product, and to precisely deliver the desired mixture concentration of the flavonoids, is provided. A batch-mixed flavonoid tincture includes an amount of at least two individual flavonoid tinctures, each flavonoid tincture being a mixture of at least a flavonoid and a solvent. The batch-mixed tincture is added to various food and beverages, or alternatively directly administered to a human or animal, to make a bioavailable amount of flavonoids to be absorbed and metabolized by the body providing demonstrated health benefits.
US10071061B2	Sterile composition A sterile composition which comprises a protein and an aliphatic polyester containing the protein and is sterilized with radiation. In this sterile composition, the structure and function (activity) of the protein are retained.
US10071058B2	Controlled-release solid dosage forms of mesalamine Described are controlled-release solid dosage forms of mesalamine. In one aspect of the invention the controlled-release solid dosage forms of mesalamine are capsules comprising a plurality of coated mini-tablets. Another aspect of the invention relates to a method of treating a patient suffering from inflammatory bowel disease, comprising the step of administering to the patient a therapeutically effective amount of the solid dosage form. The invention also relates to methods of inducing remission of inflammatory bowel disease and maintaining remission of inflammatory bowel disease. In certain aspects, the inflammatory bowel disease is ulcerative colitis or Crohn's disease.
US10071057B2	Pharmaceutical formulation containing gelling agent Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together with one or more pharmaceutically acceptable excipients; the dosage form further including a gelling agent in an effective amount to impart a viscosity unsuitable for administration selected from the group consisting of parenteral and nasal administration to a solubilized mixture formed when the dosage form is crushed and mixed with from about 0.5 to about 10 ml of an aqueous liquid; the dosage form providing a therapeutic effect for at least about 12 hours when orally administered to a human patient.
US10071055B2	Reducing or non-reducing polynucleotide polymer for drug delivery and method for preparing same The present invention relates to a reducing or non-reducing polynucleotide polymer using a nucleotide from AMP, ADP, ATP, GMP, GDP, GTP, CMP, CDP and CTP, 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC), and N-hydroxy-succinimide (NHS) for drug delivery and a method for preparing same, and provides a reducing or non-reducing polymer synthesized by using nucleotides, a method for preparing same, and a polymer composition for drug delivery containing the reducing or non-reducing polymer. The present invention relates to a drug delivery carrier for delivering proteins or peptides to a targeted area through electrostatic attraction, by obtaining a negatively (−) charged polymer by using nucleotides to synthesize the reducing or non-reducing polymer, which is easily breakable due to disulfide bonds, and then bonding the negatively (−) charged polymer with a positively (+) charged protein or peptide, wherein a polymer derived from a non-viral drug delivery carrier containing the novel reducing or non-reducing polymer is capable of effectively enabling escape of a drug, delivered by means of proton buffering activity, from an endosome to other organelles in a cell.
US10071052B2	Method for the prevention and treatment of acne A system for treating and preventing multiple forms of acne includes applying a solution to the skin to assist maintaining the skin's natural acidic mantle of 4.0 to 6.5, preserve moisture transport properties, and maintain specialized lipid content, allowing the skin to function normally, and assisting the skin to heal wounds caused by acne and associated bacterial infections. The method steps include one or more of the following: applying the formulation with surfactants incorporated therein to the skin as a cleanser, rinsing with water; applying the solution, with or without surfactants, and allowing the solution to air dry; repeating the applications and allowing them to air dry throughout the day; and repeating the cleansing and rinsing steps and applying the solution and allowing to air dry before retiring. One or more of the method steps may be repeated on a continual basis, typically daily, for an extended period of time.
US10071051B2	WT1 peptide cancer vaccine composition for transdermal administration The present invention provides a cancer vaccine composition for transdermal administration for cellular immunity induction, comprising (i) a WT1 peptide and/or a modified WT1 peptide; and (ii) a pharmacologically acceptable acid as a first cellular immunity induction promoter, or a pharmacologically acceptable salt thereof.
US10071050B2	Cosmetic composition containing exosomes extracted from stem cell for skin whitening, antiwrinkle or regeneration A cosmetic composition for skin whitening, wrinkle improvement or skin regeneration includes, as an active ingredient, exosomes derived from stem cells comprising proliferating stem cells.
US10071042B2	External dermatological agent for anti-ageing The present invention aims to provide an external dermal composition for anti-ageing, which prevents or improves apparent skin problems such as age-related or senescent wrinkles, fine wrinkles, saggings, spots, etc., as well as maintaining or enhancing the skin barrier functions. The object is solved by providing an external dermal agent for anti-ageing, which contains as an effective ingredient(s) one or more members selected from the group consisting of adenosine N1-oxide 5′-phosphate, analogs thereof, and their salts.
US10071032B2	High salt toothpaste and methods for using same Compositions and methods of treating and/or preventing conditions of the oral cavity, e.g. gingivitis, comprise applying a toothpaste composition comprising at least 5% sodium chloride in a toothpaste base comprising a zinc salt, non-silica calcium carbonate abrasive and humectant, to the oral surfaces, e.g., the teeth and gums, of a patient in need thereof.
US10071031B2	Methods for reducing oral malodor in non-human animals Oral compositions and methods of use thereof are provided herein. The oral compositions comprise a first component comprising at least one Eh-raising compound and a pharmaceutically acceptable carrier, and a second component comprising at least one zinc compound, an anti-microbial agent and a pharmaceutically acceptable carrier.
US10071025B2	Handsfree bottle support harness A handsfree bottle support harness for supporting a bottle. The handsfree bottle support harness includes a base having a first end and second end, a top surface and bottom surface, wherein the top surface contains a channel tapering from the first end to the second end. The channel is configured to hold the mouth of a bottle facing the second end of the base. The bottle is held in place by a strap having a first end connected to the first end of the base and a second end removably secured to the second end of the base. The base contains a belt within a compartment therein having a pair of distal ends configured to removably secure to one another. In another embodiment, an attachable component is removably securable to the base to allow for the height adjustment of the bottle position.
US10071024B1	Wearable pillbox reminder A wearable pillbox and a method are described. The pillbox includes a first compartment hingedly connected with a first cover and configured to store medicine to be consumed at a first dose time, a second compartment hingedly connected with a second cover and configured to store medicine to be consumed at a second dose time, the second compartment located adjacent to the first compartment and the second cover configured to open or close independently of the first cover of the first compartment, a display attached to the first cover and the second cover allowing the first cover to open or close independently of the second cover, and processing circuitry configured to transmit an alert signal to the display when the first dose time is reached.
US10071022B2	Storage containers for pharmaceutical dispenser Devices dispense medicine and dietary supplements in solid dosage form. The dimensions of the selection slots for the solid dosage forms in a device can be customized in depth by adding or subtracting spacers, and in width by adding or subtracting thickness inserts, or otherwise by employing components of suitable dimensions. Also, structures and methods for resolving jams of solid dosage forms are disclosed.
US10071020B2	Devices for transferring fluid to or from a vial In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.
US10071019B2	Portable temperature-regulating apparatus for medicaments The invention relates to a portable apparatus for regulating the temperature of medicaments in solid or liquid form. A temperature-regulating apparatus according to the invention comprises a housing with at least one accommodating chamber, with at least one temperature-regulating device for regulating the temperature of the accommodating chamber, in particular a thermoelectric temperature-regulating device, with at least one inputting means capable of registering an insertion of a medicament container into the accommodating chamber or an immediately imminent insertion, and of controlling the temperature-regulation of the accommodating chamber depending thereon.
US10071017B2	Chest compression monitor with rotational sensing of compressions for discrimination of CPR movement from non-CPR movement A chest compression monitor for measuring the depth of chest compressions achieved during CPR. A sensor of the chest compression monitor is disposed within its housing such that compression of the housing due to CPR compressions, and its resultant deformation, is detected by the sensor and used by the control system as the starting point for calculating chest compression depth based on an acceleration signal indicative of the downward displacement of the chest.
US10071015B2	Wearable device for improving tactile sensitivity A method increases a tactile sensitivity of a fingertip of a user with a wearable device. The wearable device includes a vibrating element, an actuator for receiving user input, and a control circuitry. The method includes positioning the vibrating element on one of a user's arm, wrist, hand, or proximal finger segment and activating the vibrating element to apply a vibrating force at a first magnitude. The method also includes receiving user input indicating that the user detected movement of the vibrating element at the first magnitude and applying the vibrating force at a second magnitude, the second magnitude being lower than the first magnitude, to increase the tactile sensitivity of at least one fingertip of the user.
US10071011B2	Compression garment inflation A test inflation cycle of fluid flow is controlled from a fluid source to each inflatable bladder of a plurality of inflatable bladders of a compression garment. Pressure signals from at least one pressure sensor are received and compared to one or more reference pressure values. One or more inflation parameters of at least one of the inflatable bladders is set based at least in part on the comparison of the pressure signals, and the inflatable bladders are inflated to a respective second pressure greater than the corresponding test inflation pressure of each bladder based at least in part on the set one or more inflation parameters.
US10071009B2	Medical examination table with integrated scale An examination table including an integrated scale with automatic taring, weight capture in the presence of patient motion, and automatic table height adjustment. The examination table includes a controller that periodically tares the integrated scale when a patient is not on the table so that the scale is ready to measure the weight of a patient without manual taring by the table operator. When a patient is on the table, the controller detects the presence of patient motion based on signals from load sensors, and captures weights for patients experiencing uncontrolled motion or tremors by averaging and comparing sampled weight values over predetermined periods of time. To insure that the patient is fully supported by the examination table before weighing the patient, the controller automatically adjusts the height of the examination table support surface so that the patient's feet are not touching the floor prior to weighing the patient.
US10071008B2	Thermotherapy device A thermotherapy device (incubator) includes a lying surface bordered by side walls with a side wall part suspended via a hinge allowing downward pivoting with a lock for an upright closed position. The locking mechanism has a closing projection that can enter an open side receptacle, with guide curve, to lock the side wall part in the upright closed position on a stationary structure of the heat therapy device. The closing projection or the receptacle is suspended so as to be linearly movable in the direction of connection lines thereof to the pivot axis of the hinge, such that the closing projection can be moved to a position in front of the open side of the receptacle. A preloading apparatus ensures that the closing projection and the receptacle are pressed together in form-closed engagement when the closing projection and the open side of the receptacle are oriented toward each other.
US10071005B2	Leg assembly for height adjustable patient support A height adjustable patient support has a frame, a pair of motor powered leg assemblies operable to vertically raise and lower the frame between a lowermost position and an uppermost position, a guide structure for longitudinally guiding an end of at least one of the pair of leg assemblies along the frame as the at least one of the pair of leg assemblies operates to vertically raise and lower the frame, and a non-motorized structure operable to longitudinally bias the end of the at least one of the pair of leg assemblies when the frame is in the lowermost position, the non-motorized structure mounted on the patient support by a mounting structure non-rigidly secured to the patient support. The non-motorized structure may assist with raising the frame from the lowermost position until motors operating the motor powered legs are able to continue with raising the frame.
US10071002B2	Absorbent article and absorbent core forming channels when wet An absorbent article for personal hygiene comprising a liquid permeable topsheet, a liquid impermeable backsheet, an absorbent core and a fibrous layer. The absorbent core comprises a core wrap and an absorbent material with superabsorbent polymers. The core wrap comprises a top side and a bottom side bonded to one other through one or more areas substantially free of absorbent material. The fibrous layer is at least partially bonded to one of the sides of the core wrap in the area substantially free of absorbent material. When the absorbent material swells, the core wrap forms one or more channels along the area substantially free of absorbent material. The formation of the channel in the absorbent core causes the formation of one or more corresponding ditches in the fibrous layer.
US10070999B2	Absorbent article An absorbent article having improved handling of body exudates. The absorbent article can minimize the amount of body exudates in contact with a wearer's skin and can minimize the incidence of leakage of body exudates from the absorbent article.
US10070997B2	Absorbent pant with advantageously channeled absorbent core structure and bulge-reducing features A disposable absorbent pant having a belt structure and a longitudinally channeled absorbent core structure is disclosed. The channels include at least one shorter, at least partially transversely-oriented secondary channel in the front and/or rear, to provide a hinge structure in the core, enabling the core to flex laterally and reduce the likelihood of undesirable bulging in the front and/or rear of the pant while it is worn, after the core has absorbed liquid and stiffened longitudinally as a result of the channeled structure.
US10070996B2	Method for producing disposable underwear-type diaper Fasteners folded in two are arranged on one main surface of a first continuous body so that ends of the fasteners are arranged on the outside of the one main surface. A second continuous body is laid over another main surface of the first continuous body in a state where one end is bent so as to be laid over the other main surface, and the first continuous body and second continuous body are bonded together to form a composite continuous body to which the one end of the fasteners is fixed. The composite continuous body is cut to form a piece on which the pair of fasteners is arranged only in a first region. The piece is folded in two along an imaginary line and overlapped, and then the other end of the fasteners is bent and laid over and fixed to a second region.
US10070995B2	Leakage-reducing dressing An adhesive dressing that reduces the leakage of wound exudate from the dressing, comprising an adhesive-coated backing sheet; and an absorbent island adhered to said adhesive-coated backing sheet by said adhesive, having a first end and a second end, wherein the absorption capacity of the absorbent island is higher at the first end than at the second end. The adhesive dressing of the invention provides extended wear time for the dressing when it is applied to wounds.
US10070994B2	Apparatuses and methods for wound therapy Some arrangements disclosed herein relate to devices and methods for treating a wound, comprising applying negative pressure to the wound through a cover applied over a wound, monitoring the internal pressure in the wound, and controlling the closure of the wound by controlling the amount that a wound packing material positioned under the cover collapses within the wound based on the monitored internal pressure. The wound packing material collapse can be controlled to ensure that the monitored internal pressure does not exceed a threshold value. Additionally, some embodiments or arrangements disclosed herein relate to a visualization element to visualize a location of a wound surface. The visualization element can comprise a radiopaque member that is configured to be positioned on or adjacent to a surface of an open wound.
US10070986B1	Testicular retraction restraints and methods Described are restraints, and methods of using and making the restraints, for restraining a man's testicular retraction response to sexual stimulation. It is believed that the restraints and methods of use thereby tend to slow or postpone the onset of the man's climax, with the potential to prolong the pleasure of the man and/or his sexual partner. More particularly, clip restraints and loop restraints are described and illustrated. The clip restraints are configured to grip a portion of the scrotum and to present deflection or obstruction features above the reposed positions of each of the man's testicles, configured to deflect or obstruct the movement of the testicles toward a retracted position associated with the onset of the man's sexual climax. Advantageously, clips according to the invention may fold to a narrow thickness, convenient for carrying in a pocket or wallet. Clip members of the restraints may be attracted by magnets, biased by springs, or manually adjusted to a stable gripping position. The loop restraints comprise left-hand and right-hand loops configured to extend around a portion of the scrotum and to define a restraint opening, confining at least a restrained portion of the respective testicle to one side of the restrained opening to limit retraction of the respective testicle through the opening in a direction toward the respective vas deferens.
US10070985B2	Cervical spine orthosis Implementations of the present disclosure overcome the problems of the prior art by providing a brace for supporting a head of a wearer. The brace includes a head frame, a strap assembly and a cervical bar. The head frame is configured to grip the head of the wearer. The strap assembly is configured to extend along the wearers waist and back. The cervical bar has a first and second ends. The first end connects to and supports the head frame. The second end connects to and is supported by the strap assembly. Advantageously, the cervical bar has a stiffness sufficient to support the head and the head frame against head drop. The brace can do this without interfering with respiratory pathways.
US10070984B2	Variable pressure upper torso braces and methods related thereto Upper torso braces to correct deformities in the upper torso of a patient are provided. The upper torso braces include a brace structure adapted to be maintained around an upper torso of an individual and to restrict outward expansion, and a variable force applicator coupled to the brace structure and positioned to contact and apply varying pressure to a target location on the upper torso. The brace structure is configured to restrict outward expansion and to provide a counteracting force for the variable force applicator during application of the variable pressure to the target location. In some instances, the upper torso braces may include a control element to adjust an amount of pressure provided by the variable force applicator to the target location. Methods of correcting a deformity on an upper torso with the upper torso braces are also provided.
US10070982B2	Link assembly, frame, and walking assistance robot A frame configured of a plurality of links pivotally connected to one another is flexibly bent, and pins that connect the plurality of links that constitute the frame are inserted into and slide in a curve-shaped slot and a slot in a vertical direction so that, even though the frame is bent, the entire length of the frame is increased and ends of the frame can be moved along a straight line that is horizontal with respect to the ground.
US10070981B2	Locking gastric obstruction device and method of use The present invention relates to a device for intermittently obstructing a bodily opening, such as a gastric opening, and includes a proximal member connected to a distal member by a tether. The proximal member is formable from an elongated and narrower configuration to a contracted or expanded but wider configuration. When employed in the stomach, the device may be arranged transluminally with the distal member disposed in the duodenum and the proximal member disposed against the pyloric valve, intermittently occluding the pyloric valve and preventing or delaying, the flow of gastric contents through the pyloric valve.
US10070976B2	Optimized stent jacket A method of stenting, comprises: implanting a stent assembly in a vessel of a subject, the stent assembly, including: a stent jacket, comprising an expansible mesh structure, formed of fibers of a diameter between about 7 micrometers and about 18 micrometers, the diameter having a property of forming a substantially stable layer of endothelial cells, covering the fibers, thus reducing platelet aggregation, and an expansible stent, operatively associated with the stent jacket. The method further comprises administering to the subject an active pharmaceutical ingredient (API) comprising a platelet aggregation reducer for a shortened time period, not exceeding six months, the shortened time period being a consequence of the property. In accordance with some embodiments, the administration of a platelet aggregation.
US10070975B2	Stents with radiopaque markers Various embodiments of stents with radiopaque markers disposed within depots in the stent, are described herein.
US10070973B2	Orthopaedic sensor module and system for determining joint forces of a patient's knee joint An orthopedic surgical device includes a tibial paddle shaped to be positioned in the patient's knee joint and a handle extending from the tibial paddle. The tibial paddle includes a sensor array positioned therein and configured to generate sensor signals indicative of the joint force of the patient's knee joint. The orthopedic surgical device also includes a control circuit configured to control a display located on the handle to provide a visual indication of the medial and lateral balance of the joint force. In some embodiments, various tibial trialing components may be coupled to the tibial paddle along with an associated adaptor.
US10070968B2	Support device and method for use Devices and methods for orthopedic support are disclosed. The device can have a first rigid section hingedly attached to a second rigid section. The device can be curved or rotated around obstructions along an access path to a target site. The device can be delivered to an intervertebral location in a patient.
US10070966B2	Femoral component for a knee prosthesis with bone compacting ridge An orthopedic knee prosthesis includes a femoral component which exhibits enhanced articular features, minimizes removal of healthy bone stock front the distal femur, and minimizes the impact of the prosthesis on adjacent soft tissues of the knee.
US10070965B2	Knee joint endoprosthesis The invention relates to a knee joint endoprosthesis has a tibia part, a femur part, a meniscus part arranged on the tibia part in mutually non-rotatable manner and a connecting device for connecting the tibia part to the femur part in articulated manner. Said femur part comprises at least one femur condyle having a femur condyle surface. Said meniscus part comprises at least one upper surface which faces the femur part and has at least one meniscus joint surface which touches the femur condyle surface of the at least one femur condyle. Said femur part and the tibia part are mounted such as to be rotatable relative to each other about a rotational axis.
US10070961B2	Fully porous prosthetic hip stem A prosthetic hip stem for use in a prosthetic hip joint. The hip stem generally includes a core having a stem portion and a neck portion, a polymer matrix layer substantially covering the stem portion of the core, and a porous metal layer substantially covering the polymer matrix layer. The polymer matrix layer connects the core and the porous metal layer, and may be injection molded therebetween. The neck portion of the hip stem has a relatively thin or slender profile which allows for an increased degree of articulating movement of the hip stem with respect to the acetabular component of a prosthetic hip joint. The neck portion of the hip stem additionally includes a version indicator element, such as a bump or a protrusion, which may be tactilely felt by a surgeon to aid the surgeon in positioning the hip stem during a minimally invasive total hip arthroplasty procedure, for example, where direct visualization of the hip stem by the surgeon may not be possible. Additionally, the core of the hip stem includes grooves, ridges, flats, dimples or other features to enhance the mechanical interconnection between the core and the polymer matrix layer.
US10070959B2	Method of texturing prosthetic implants A method of treating an articular surface of a metal orthopedic implant includes polishing the surface, blasting the surface with a blast media after the first polishing step and polishing the blasted surface of the metal orthopedic implant after the blasting step. The blasting step roughens the surface to create a surface skew Rsk/Ssk defined by peaks and valleys. The second polishing step reduces the surface skew to a negative skew Rsk/Ssk and produces an average roughness Ra/Sa that is acceptable. Lubrication at the interface of the treated articular surface and the corresponding bearing articular surface is improved, thereby improving wear resistance. Both polishing steps may be performed by drag finishing the surface through an abrasive media.
US10070958B2	Subchondral treatment to prevent the progression of osteoarthritis of the joint Methods for the prevention, or delayed onset or progression of, bone marrow edema or bone marrow lesion, and subchondral treatment to prevail the progression of osteoarthritis of a joint are disclosed. The methods involve treating the subchondral bone, while preserving, as much as possible, the joint's articular and cartilage surface. The methods could be performed before, during, or after an initial arthroscopic surgery to repair the joint. Associated devices and instruments for treatment of the subchondral bone are also disclosed.
US10070957B2	Membrane encapsulated joint implant sealed under vacuum For a membrane encapsulated joint implant sealed under vacuum, a joint implant includes an outer cup, an inner cup, a joint head, a joint membrane, a lubricant, and an implant stem. The outer cup attached at a proximal bone. The nests within the outer cup and receives a joint head, the inner cup comprising an inner cup rim. The joint head is disposed within the inner cup and forms a bearing that rotates within the inner cup. The joint membrane sealed to the inner cup rim and vacuum seals the joint head within the inner cup to form a capsular space. The lubricant is disposed within the capsular space. The implant stem that is attached to a distal bone and that attaches through the joint head through the joint membrane.
US10070953B2	Corneal implant and method of delivering a corneal implant A method of inserting and securing a corneal implant in engaging and fluid-flow limiting relation to the posterior cornea, such as to treat edema. The method includes securing a corneal implant in fluid flow limiting relation to the posterior cornea through an incision in the eye and securing it in place by a variety of steps such as corneal insertion or laser bonding, and preferably by inserting a removable corneal implant including a central region and a plurality of retention member(s) disposed on the periphery thereof into the eye so as to releasably and removably engage a portion of the eye and thereby retain the corneal implant in abutting and engaging relation with the posterior cornea. The retention members of the corneal implant may also comprise haptic leg(s) extending from the central region.
US10070948B2	Biosynthetic implant for soft tissue repair An implant and a process for preparing such an implant are disclosed. The implant includes a porous layer including collagen, a non-porous layer including a collagenic constituent, and a reinforcement component. The non-porous layer is joined to the porous layer and the reinforcement member is embedded into the non-porous layer. The porous layer has a three dimensional density ranging from about 20 mg collagen/cm3 to about 200 mg collagen/cm3.
US10070942B1	Orthodontic cinch back instrument The orthodontic cinch back instrument is an orthodontic tool used for cinching back an end of an orthodontic wire. The orthodontic cinch back instrument includes an elongated handle portion which extends along a longitudinal axis and has opposed first and second ends. First and second shank portions are respectively secured to, and extend longitudinally from, the first and second ends of the elongated handle portion. First and second arcuate head supports are respectively secured to, and extend from, the first and second shank portions. The first and second arcuate head supports are positioned and contoured antisymmetrically with respect to one another about a lateral axis. First and second heads are respectively secured to the first and second arcuate head supports and are positioned and angled antisymmetrically with respect to one another about the lateral axis. Each of the first and second heads has a slot formed therein.
US10070938B2	Stabilization device and method for surgical localization wire A wire stabilization device and method for stabilizing a localization wire during a tissue diagnostic procedure are disclosed. The wire stabilization device includes a device body and a device base. The device body is joined to the device base. The device body includes a base portion, a cover portion, a cover hinge, and a gripping feature. The cover hinge connects the base portion to the cover portion and allows the cover portion to rotate between open and closed positions. The gripping feature holds the localization wire between the base portion and the cover portion. The device base attaches to a patient's skin to stabilize the device body while the localization wire is held between the base portion and the cover portion.
US10070933B2	Custom procedure kit A custom procedure kit is provided, which comprises a plurality of medical-procedure tools and a cover that is wrapped around the plurality of medical-procedure tools to form wrapped tools. An outer container is fully disposed about the wrapped tools, and at least one sheet is disposed between the outer container and the wrapped tools. The sheet includes a listing of the plurality of medical-procedure tools and, for at least some of the medical-procedure tools, an unselected end-user selectable field.
US10070932B2	System and method for maneuvering coils power optimization An optimization unit controls electrical currents of a set of electromagnets to generate a wanted maneuvering magnetic field pattern (MMP) for moving an in-vivo device in the GI system. The optimization unit may calculate a magnetic force and a magnetic field to maneuver the in-vivo device from a current location and/or orientation to a new location and/or orientation. The optimization unit may solve a magnetic force optimization problem with respect to the magnetic force in order to determine electrical currents suitable for generating the wanted MMP. The optimization unit may additionally or alternatively solve a minimum electrical power optimization problem with respect to the electrical power to be consumed by the electromagnets in order to recalculate or adjust the electrical currents. The optimization unit may solve one or more of the optimization problems while complying with a set of constraints associated with or derived from each type of optimization objective.
US10070931B2	System and method for maintaining a tool pose A system and method of maintaining a tool pose for a computer-assisted medical device with an articulated arm including one or more first joints and one or more second joints, a tool distal to the first joints and the second joints, and a control unit coupled to the first joints and the second joints. The control unit maintains a pose of the tool during movement of the first joints using the second joints by determining a reference coordinate frame for the tool, determining a reference transform of the tool in the reference coordinate frame prior to the movement of the first joints, determining an actual transform of the tool in the reference coordinate frame while the first joints are being moved, determining differences between the reference transform and the actual transform, and maintaining the pose of the tool by driving the second joints based on the differences.
US10070928B2	Implant placement planning A method of planning a procedure to fasten an implant to a bone includes displaying a model of the bone and a model of the implant on a display device. The model implant is positioned on the model bone in a desired implant position. A first boundary volume of a first fastener configured to fasten the prosthesis to the bone is also displayed on the display device. The first boundary volume represents a range of possible positions that the first fastener may have with respect to the prosthesis when fastened to the bone. The boundary volume may be used to determine a desired size, shape, and/or positioning of the fastener with respect to the bone.
US10070910B2	Apparatus and methods for cryogenically ablating tissue and adjusting cryogenic ablation regions Apparatus and methods for performing cryogenic ablation of tissue and adjusting the size and/or location of a cryogenic cooling region. A cooling assembly may include tubes for dispensing and exhausting a coolant or refrigerant. One or both of the tubes may be moved, e.g., slidably adjusted, in order to adjust the location or size of a cryogenic ablation region. The cooling assembly may be integrated into cryogenic ablation devices including a cryogenic balloon device that includes an inner inflatable balloon and another balloon that is at least partially wrapped around the inner balloon and carries refrigerant for performing cryo-ablation. Electrodes permit electrical mapping of tissue before or after cryo-ablation to verify success of the procedure.
US10070907B2	Angled nozzle with connection assembly system An apparatus for bone cement delivery comprising, a proximal nozzle having a proximal end configured to couple to a bone cement source and a first distal delivery end having a circular cross section, a distal nozzle having a proximal end configured to slideably couple to the first distal delivery end and a second distal delivery end having an oblong cross section, that can be slanted, and an attachment mechanism configured to slideably retain the distal nozzle to the proximal nozzle.
US10070906B2	Device and method for securing a ligature to an osseous structure Embodiments disclosed herein provide a device for securing a ligature to an osseous structure, the device comprising a first part, a second part, a flexible elongate member for engaging the osseous structure, a closure element, and a deformable element between the first and second parts for holding open a gap G between them. The flexible elongate member is threaded through an orifice in the first part and the gap G. The closure element is configured for clamping the first and second parts against each other, overcoming the resilience of the deformable element, so as to frictionally lock the flexible elongate member threaded through the gap G. Embodiments disclosed herein also provide a method for using the device.
US10070903B2	Stereotactic computer assisted surgery method and system A computer assisted surgical system that includes an apparatus for imaging a region of interest of a portion of an anatomy of a subject; a memory containing executable instructions; and a processor programmed using the instructions to receive two or more two-dimensional images of the region of interest taken at different angles from the apparatus and process the two or more two-dimensional images to produce three dimensional information associated with the region of interest.
US10070902B2	Spinal implant system and method A spinal implant comprises a body including an inner surface that defines a cavity. The inner surface includes a baffle. The body is disposable between a contracted configuration and an in vivo expandable configuration. Systems and methods are disclosed.
US10070897B1	Translational posterior cervical polyaxial screw A translating polyaxial bone screw assembly for anchoring a connecting rod to a spinal vertebra comprises a bone screw having a threaded shank and a head coupled to a yoke. The yoke has at one end a rod receiving channel for receiving a connecting rod and an opposite end that is coupled to the bone screw by a coupling assembly. The coupling assembly couples the yoke for polyaxial movement relative to the bone screw and for translational movement of the yoke in a direction transverse to the axis of the bone screw. The coupling assembly comprises a biasing element supported for joint movement with the yoke that provides a manually surmountable tension force between the yoke and bone screw head that is maintained during polyaxial and translational movement. A fastening element is supported by the yoke for securing the connecting rod between the fastening element and the coupling assembly.
US10070896B2	Anchoring member suitable for use in a polyaxial bone anchoring device and polyaxial bone anchoring device with an enlarged pivot angle to one side An anchoring member is provided suitable for use in a polyaxial bone anchoring device, the anchoring member (1) comprising a bone anchoring section (2) with a bone engagement structure in at least a portion of an outer surface thereof; a head (3); a central axis (C) extending through a center of the head (3) and the bone anchoring section (2), and a neck portion (24; 24′; 24″; 24′″) between the bone anchoring section and the head, wherein the neck portion is asymmetric with respect to the central axis (C); and wherein the bone anchoring section (2) has a contour in a circumferential direction adjacent to the neck portion and wherein the neck portion is at least partially recessed with respect to the contour of the bone anchoring section at one side and extends beyond the contour of the bone anchoring section at an opposite side from the central axis.
US10070894B2	Compliant vertebral attachment device In one general aspect, a vertebral attachment device can include an attachment member having a curved shape defining a concave surface, a flex structure included in the attachment member, and an anchor member coupled to the attachment member and protruding from the concave surface.
US10070889B2	Inorganic pyrophosphate and uses thereof The present invention provides a new and improved sperm stimulating additive comprising a certain amount of inorganic pyrophosphate (PPi). Addition of PPi in the media for human/animal in vitro fertilization (IVF) improves fertilization rate; addition of PPi in the semen extender for farm animal artificial insemination (AI) may improve pregnancy rates; furthermore, mammalian oocytes matured in vitro in a medium including PPi attain improved fertilization and developmental potential, while embryos cultured in medium supplemented with PPi have improved development to blastocyst.
US10070885B2	Soft tissue coring biospy devices and methods An excisional device for either handheld or stereotactic table/MRI use may comprise a work element configured to rotate at a first rotation rate and comprising at least one articulable beak configured to cut tissue in a longitudinal direction. Helical elements or equivalent assemblies may be configured to transport tissue cut by a work element and may be co-axially disposed relative to the work element and may be operative to rotate at rotation rates that may be different from the work element rotation rate. Flush and vacuum tissue transport mechanisms may be incorporated in replacement of or in conjunction with helical elements. A proximal sheath and a distal sheath may be co-axially disposed relative to a work element and may be configured to rotate a work element and to actuate a beak or beaks. A simplified embodiment of this device may be applicable to field use where power sources for actuation may be limited.
US10070883B2	Systems and method for ultra-high frequency ultrasound treatment A non-invasive ultra-high frequency ultrasound treatment method and system are provided. An exemplary method and system comprise a high-frequency ultrasound transducer system configured for providing ultrasound treatment to a patient such that the superficial and/or subcutaneous regions of the patient can be treated. An exemplary high-frequency ultrasound transducer system comprises a control system and a transducer configured to provide treatment to the superficial and/or subcutaneous regions of interest. The high-frequency ultrasound transducer may be configured to operate at higher frequencies and controlled power levels to provide treatment to the superficial and/or subcutaneous regions of interest. For example, higher frequencies within the range from approximately 20 MHz to 500 MHz or more may be utilized.
US10070881B2	Method of providing for the minimization of extravasation during arthroscopic surgery The devices and methods shown provide for the minimization of extravasation during arthroscopic surgery. The extravasation minimization device allows a surgeon to drain excess fluids from the soft tissue surrounding the surgical field while also providing a stable surgical portal for arthroscopic surgical instruments.
US10070880B2	Miniature device platform for navigation on moving organs A device for gripping tissue that is inside of a patient for use in delivering therapy is provided. The device may include a first gear that rotates and that engages the tissue. A second gear that also rotates may be included and may likewise engage the tissue. A spacing mechanism may be included in the device that adjusts the spacing between the first and second gears such that the first and second gears are moved closer to one another and moved farther from one another.

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