Document Document Title
US09982287B2 Enterokinase cleavable polypeptides
The present invention relates to Enterokinase-cleavable polypeptides comprising an Enterokinase cleavage site connected to a polypeptide and their use for making the target polypeptide by expression. The invention also relates to DNA sequences, vectors and host cells for use in expressing the Enterokinase-cleavable polypeptides.
US09982286B2 Medium for the protein-free and serum-free cultivation of cells
A medium is described for the protein-free and serum-free cultivation of cells, especially mammalian cells, whereby the medium contains a proportion of soy hydrolysate.
US09982285B2 Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
The present invention relates to polypeptides having cellulolytic enhancing activity, catalytic domains, and carbohydrate binding domains, and polynucleotides encoding the polypeptides, catalytic domains, and carbohydrate binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains, and carbohydrate binding domains.
US09982284B2 Enzymatic hydrolysis of disaccharides and oligosaccharides using alpha-glucosidase enzymes
A method is disclosed for hydrolyzing an alpha-1,5 glucosyl-fructose linkage in a saccharide (disaccharide or oligosaccharide) such as leucrose. This method comprises contacting the saccharide with an alpha-glucosidase enzyme such as transglucosidase or glucoamylase under suitable conditions, during which contacting step the enzyme hydrolyzes at least one alpha-1,5 glucosyl-fructose linkage of the saccharide. This method is useful for reducing the amount of leucrose in a filtrate isolated from a glucan synthesis reaction, for example.
US09982277B2 Methods and compositions for target DNA modification
The disclosure provides compositions and methods for increasing efficiency of Cas9-mediated target DNA modification. Specifically, the disclosure provides compositions and methods for carrying out site-directed modification of a target DNA, the methods comprising contacting the target DNA with: a) a complex comprising a Cas9 polypeptide and a guide RNA, and b) a Rad51 polypeptide. The site-directed modification of a target DNA can be carried out in a living cell in vitro, in a living cell in vivo, or in a cell-free system in vitro.
US09982276B2 Penton-mutated, integrin-retargeted adenovirus vectors with reduced toxicity and their use
The present invention describes generation and the use of adenovirus variants (Ad) possessing modified capsid penton base protein where mutations in the penton based RGD loop are made to avoid Ad binding to cellular β3-integrins. Specifically, the ablation of Ad penton base interaction with cellular β3-integrins results in reduced activation of inflammation after intravenous Ad administration. Further, the introduction into penton RGD loop of non-RGD containing peptides, which mediate virus entry into the cell via new cellular receptors, allows for the efficient Ad-mediated gene delivery into target cells in vivo after intravascular virus administration and triggers significantly reduced toxicity associated with Ad injection.
US09982275B2 Promoters, expression cassettes, vectors, kits, and methods for the treatment of achromatopsia and other diseases
The present invention provides isolated promoters, transgene expression cassettes, vectors, kits, and methods for treatment of genetic diseases that affect the cone cells of the retina.
US09982272B2 Algal mutants having a locked-in high light acclimated phenotype
Mutant photosynthetic microorganisms having reduced chlorophyll and increased photosynthetic efficiency are provided. The mutants have a locked in high light-acclimated phenotype, in which many of the photosynthetic parameters characteristic of high light acclimated wild type cells are found in the LIHLA mutants when acclimated to low light, such as reduced chlorophyll, reduced NPQ, higher qP, higher Ek, higher Pmax per unit chlorophyll with little to no reduction in Pmax per cell, and higher rates of electron transport through photosystem II over a wide range of light intensities. Provided herein are constructs for attenuating or disrupting genes are provided for generating mutants having the LIHLA phenotype. Also provided are methods of culturing LIHLA mutants for the production of biomass or other products.
US09982266B2 Methods and pharmaceutical compositions for treatment of cystic fibrosis
The present invention relates to a method and compositions for the treatment of cystic fibrosis.
US09982263B2 Conserved HBV and HCV sequences useful for gene silencing
Conserved consensus sequences from known hepatitis B virus strains and known hepatitis C virus strains, which are useful in inhibiting the expression of the viruses in mammalian cells, are provided. These sequences are useful to silence the genes of HBV and HCV, thereby providing therapeutic utility against HBV and HCV viral infection in humans.
US09982255B2 Capture methodologies for circulating cell free DNA
A nucleic acid patch method for amplifying target nucleic acid sequences in circulating free DNA or residual DNA samples where the defining ends of the target nucleic acid sequences are unknown.
US09982251B2 Large volume ex vivo electroporation method
An object of the invention is to provide an electroporation method for treating vesicles with exogenous material for insertion of the exogenous material into the vesicles which includes the steps of: a. retaining a suspension of the vesicles and the exogenous material in a treatment volume in a chamber which includes electrodes, wherein the chamber has a geometric factor (cm.sup.−1) defined by the quotient of the electrode gap squared (cm.sup.2) divided by the chamber volume (cm.sup.3), wherein the geometric factor is less than or equal to 0.1 cm.sup.−1, wherein the suspension of the vesicles and the exogenous material is in a medium which is adjusted such that the medium has conductivity in a range spanning 50 microSiemens/cm to 500 microSiemens/cm, wherein the suspension is enclosed in the chamber during treatment, and b. treating the suspension enclosed in the chamber with one or more pulsed electric fields. With the method, the treatment volume of the suspension is scalable, and the time of treatment of the vesicles in the chamber is substantially uniform.
US09982247B2 Method for purifying transgenic factor VII/VIIA
An anti-Factor VII affinity ligand that is particularly useful for purifying recombinant human activated Factor VII from transgenic sources. The affinity ligand combined with other orthogonal chromatographic steps allows the preparation of a highly purified FVII solution fully activated free of aggregates with a low percentage of degraded or oxidized FVII forms.
US09982244B2 Recombinase mutants
Presented herein are recombinases for improved recombinase-mediated amplification of nucleic acids, such as a PCR-library having single-stranded adapter regions, on a patterned flow cell surface for improved cluster amplification, as well as methods and kits using the same.
US09982238B2 Method for producing regenerative organ primordium provided with guide for transplantation, composition containing regenerative organ primordium provided with guide for transplantation produced thereby, and method for transplanting regenerative organ primordium provided with guide for transplantation
A method for producing a regenerative organ germ for transplantation includes using regenerative organ germ for transplantation ensuring continuity with a recipient after transplantation and facilitating transplantation procedures. A method for producing a regenerative organ germ provided with a guide for transplantation includes preparing a regenerative organ germ by closely contacting a first cell mass, which substantially consists of mesenchymal cells, and a second cell mass, which substantially consists of epithelial cells, culturing these cell masses within a support, and inserting the guide into the regenerative organ germ.
US09982236B2 Cell populations, methods of transdifferentiation and methods of use thereof
The present invention provides methods for the sequential and temporally-regulated administration of pancreatic transcription factors to induce non-pancreatic cells to transdifferentiate and mature along the pancreatic β-cell lineage. The present invention also provides methods for identifying, isolating and enriching transdifferentiation predisposed cells and methods for treating a degenerative pancreatic disorder such as diabetes.
US09982234B2 Culture medium composition for improving regenerative capacity of stem cells, and stem cell culturing method using same
The present invention relates to a medium composition for enhancing the self-renewal ability of stem cells, which contains apelin, and a method of culturing stem cells using the medium composition. According to the present invention, stem cells can be effectively cultured to proliferate without changing the characteristics of the cells, and the telomerase activity of stem cells can be increased. Thus, the efficacy of cell therapy based on stem cells can be significantly improved.
US09982231B2 Methods for reprogramming differentiated non-cardiac cells into cardiomyocytes
Compositions and methods are described herein for chemically inducing cells to change their differentiation state and become cardiac progenitor cells or cardiomyocytes.
US09982229B2 Use of hydrophobins to increase gas transfer in aerobic fermentation processes
The present disclosure provides methods, compositions and apparatuses for increasing gas transfer in fermentation processes.
US09982227B2 System and method for production of on-demand proteins in a portable unit for point of care delivery
A portable and mobile bioprocessing system and method for protein manufacturing that is compact, integrated and suited for on-demand production of any type of proteins and for delivery of the produced proteins to patients or for assay purposes. The portable system and method can also be used for efficient on-demand production of any type of protein with point-of-care delivery.
US09982220B2 Efficient surfactant system on plastic and all types of ware
Surfactant systems and compositions incorporating the same are disclosed for use as rinse aids on plastics and other wares. The surfactant systems and compositions include both liquid and solid formulations, along with methods of use for treating plastics and other wares. The surfactant systems and compositions provide synergistic combinations allowing lower actives in composition formulations of the plastic-compatible surfactant systems providing good sheeting, wetting and drying properties.
US09982219B2 Sustainably sourced, non-hydrogenated, plant based candle compositions
The present disclosure relates to candle compositions. In particular, the disclosure relates to rice bran wax/coconut oil candle compositions and methods for making such compositions.
US09982217B2 Aliphatic nitrile with rosy odor
The present invention concerns compound of formula in the form of any one of its stereoisomers or a mixture thereof, and wherein R1 and R1′, independently from each other, represent a hydrogen atom or a methyl group provided that one of said groups represent a hydrogen atom and the other a methyl group; R2 and R3, independently from each other, represent substituents of the saturated ring and are a hydrogen atom or a C1-3 alkyl group; and n is an integer varying between 1 and 4; and their use in perfumery to impart odor notes of the floral, rosy type.
US09982215B2 Solid lubricant, electrophotographic image forming apparatus, and image forming method
A solid lubricant is supplied to a surface of an image carrier of an electrophotographic image forming apparatus. The solid lubricant contains a fatty acid metal salt and polypropylene, and the polypropylene has an acid value of 1 mg KOH/g or more. The solid lubricant is a solid substance of a melt mold containing the fatty acid metal salt and the polypropylene.
US09982210B2 Composition containing heterocyclic compounds and a method of lubricating an internal combustion engine
The present invention relates to a lubricating composition containing (a) an oil of lubricating viscosity; and (b) a compound selected from the group consisting of: (i) an ester-containing heterocycle; (ii) an amide-containing heterocycle; and (iii) a pyrimidine, wherein the ester-containing heterocycle and the amide-containing heterocycle have a hydrocarbyl group containing 6 to 40 carbon atoms. The invention further provides for a method of supplying an internal combustion engine with the lubricating composition.
US09982208B2 Diesel fuel compositions
The present disclosure provides a diesel fuel composition containing DMC and multifunctional additives to reduce particulate emission, improve efficiency and be used in cold and/or hypoxia conditions.
US09982203B2 Process for the conversion of a heavy hydrocarbon feedstock integrating selective cascade deasphalting with recycling of a deasphalted cut
Process for converting a heavy hydrocarbon feedstock with initial boiling point of at least 300° C. comprising: a) hydroconverting at least part of said feedstock; b) separating the effluent from stage a) to obtain light and heavy liquid fractions; c) at least two stages of deasphalting in series at least part of the heavy liquid fraction originating from stage b), allowing to separate at least one fraction of asphalt, at least one fraction of heavy deasphalted oil (heavy DAO) and at least one fraction of light deasphalted oil (light DAO), at least one deasphalting stage being carried out using a mixture of at least one polar solvent and at least one apolar solvent, said deasphalting stages being under subcritical conditions of the mixture of solvents; d) recycling at least part of said heavy deasphalted oil cut from stage c) upstream of hydroconverting a) and/or of the inlet of separating b).
US09982193B2 Preparation method and station for non-caking agent solutions
Process and dosing station (1) for the preparation of a solution of a non-caking agent, wherein a concentrate of the non-caking agent is circulated in a loop (6) and wherein the concentrate is subsequently diluted by water to obtain the solution. A flow of the concentrate can be drawn from the circulation loop (6) and mixed with a flow of water. The obtained solution can subsequently be fed into a second recirculation loop (12). A flow of solution can be drawn off from the second recirculation loop for being dosed into an amount of salt.
US09982187B2 Delayed delivery of chemicals in a wellbore
Methods and systems of delivering a treatment chemical are disclosed, including providing a plurality of porous particles each having an outer surface, wherein each of the plurality of porous particles comprises a plurality of pores; infusing the plurality of porous particles with the treatment chemical; coating the plurality of porous particles with a degradable film; adding the plurality of porous particles to a carrier fluid, wherein the degradable film substantially separates the treatment chemical from the carrier fluid; introducing the carrier fluid into a formation; and allowing the degradable film to degrade within the formation.
US09982186B2 Solid acids for acidizing subterranean formations
Methods of acidizing subterranean formations using solid acids are described. The methods include providing a treatment fluid containing a solid acid chelating agent and introducing the treatment fluid into the subterranean formation. The solid acid chelating agent includes at least one aminopolycarboxylic acid functional group and at least one phosphonic acid functional group. The treatment fluid is substantially free of an additional acid or acid-generating compound.
US09982184B2 Terpolymer compositions
Salt-tolerant friction-reducing terpolymer compositions are provided. The compositions can be used in a method of reducing friction resulting from turbulent flow in an aqueous fracturing fluid in a subterranean fracturing process.
US09982183B2 Process for treating an underground formation
The present invention relates to processes for consolidating an underground formation with a consolidating mineral. The consolidating material is a carbonate and is produced from an alkaline treatment fluid containing, in at least some embodiments, environmentally friendly and inexpensive components. In one embodiment, the process can be applied to consolidation of an underground formation during or following drilling. The present invention also provides a treatment fluid suitable for use in such processes.
US09982179B2 Refrigerant with lubricating oil for replacement of R22 refrigerant
An apparatus and method wherein potential ozone layer-damaging chlorodifluoromethane (Refrigerant R-22) is substituted with a mix of less environmentally damaging refrigerants pentafluoroethane and tetrafluoroethane in chlorodifluoromethane-based air-cooling systems mainly in residential cooling. While less environmentally damaging than chlorodifluoromethane, the substitute refrigerant has a temperature-pressure relationship similar to that of chlorodifluoromethane, making the substitute refrigerant suitable for use with chlorodifluoromethane-based air-cooling systems. In this event, it is mixed with a relatively small percentage of a lubricating oil which is compatible with both the unit refrigerant and typical R-22 system design.
US09982176B2 Abrasive particles having a unique morphology
An abrasive particle having an irregular surface, wherein the surface roughness of the particle is less than about 0.95. A method for producing modified abrasive particles, including providing a plurality of abrasive particles, providing a reactive coating on said particles, heating said coated particles; and recovering modified abrasive particles.
US09982171B2 Hot melt adhesive with functionalized metallocene catalyzed polyolefins
A hot melt adhesive composition containing a functionalized polymer, namely, a metallocene catalyzed polyolefin elastomer grafted with maleic anhydride, together with a non-functionalized secondary polymer, namely, a metallocene catalyzed random or block polyolefin elastomer having a melt index equal to or greater than 15, a first tackifying resin having a softening point of at least 95° C., and a wax. The composition may optionally include an aromatic reinforcing resin having a softening point equal to or higher than 115° C., and a plasticizer. These hot melts provide superior hot tack, excellent adhesion, flexibility, and heat resistance above 150° F. in applications such as rigid packaging, hot fill packaging, and bottle labeling.
US09982169B2 Method and apparatus for adhesive bonding in an aqueous medium
The disclosure is directed to an adhesive material which can be applied underwater comprising hydrophilic adhesive molecules. In other embodiments, the adhesive material may also include hydrophilic polymers and/or an oxidizing agent.
US09982166B2 Metal oxide-polymer composite particles for chemical mechanical planarization
CMP processes, tools and slurries utilize metal oxide-polymer composite particles that include metal oxide particles and a polymer core. The metal oxide particles are modified with a modifying agent and are partially or fully embedded within the polymer core. Using these processes, tools and slurries can enhance removal rates, reduce defectivity and increase cleanability with respect to comparable systems and substrates.
US09982165B2 Polishing slurry for silicon, method of polishing polysilicon and method of manufacturing a thin film transistor substrate
A polishing slurry for silicon, a method of polishing polysilicon, and a method of manufacturing a thin film transistor substrate, the slurry including a polishing particle; a dispersing agent including an anionic polymer, a hydroxyl acid, or an amino acid; a stabilizing agent including an organic acid, the organic acid including a carboxyl group; a hydrophilic agent including a hydrophilic group and a hydrophobic group, and water, wherein the polishing particle is included in the polishing slurry in an amount of about 0.1% by weight to about 10% by weight, based on a total weight of the slurry, a weight ratio of the polishing particle and the dispersing agent is about 1:0.01 to about 1:0.2, a weight ratio of the polishing particle and the stabilizing agent is about 1:0.001 to about 1:0.1, and a weight ratio of the polishing particle and the hydrophilic agent is about 1:0.01 to about 1:3.
US09982161B2 Graft copolymers with grafted polymeric arms, their preparation and use
A graft copolymer composition including: a polymeric backbone derived from a plurality polymerizable ethylenically unsaturated monomers; and a plurality of polymeric arms attached pendant to the polymeric backbone. The polymeric arms include: (a) at least two different polymeric arms comprising: a condensation copolymer arm and a random copolymer arm, (b) a polymeric arm having segments of (i) a condensation copolymer segment and (ii) a random copolymer segment, wherein said condensation copolymer segment and random copolymer segment are linked to each other; (c) or combinations thereof.
US09982158B2 Coatings having filler-polymer compositions with combined low dielectric constant, high resistivity, and optical density properties and controlled electrical resistivity, devices made therewith, and methods for making same
UV curable coatings containing dual phase filler-polymer compositions with high resistivity, low dielectric constant, good optical density, and controlled electrical resistivity are described, and cured coatings or films formed thereof, along with their use in black matrix, black column spacers, and other light shielding coating elements in LCD. Devices having these black matrices, black column spacers, and/or other light shielding coating elements, and methods of preparing and making these various materials and products are also described.
US09982156B1 Transmissive surfaces and polymeric coatings therefore, for fortification of visible, infrared, and laser optical devices
A coated material contains a substrate and a protective coating in which the protective coating is formed of a plurality of monomer units covalently bonded to a surface of a substrate such that each monomer unit contains a hydrophobic tail group covalently bonded to the surface of the substrate through an organic linking group. The protective coating is formed by a process including the steps of contacting the surface of the substrate with a surface activator containing a fluoride-containing compound and an organic solvent to form an activated surface, contacting the activated surface with a protective reagent to form an initial coated surface, and contacting the initial coated surface with a thinning agent containing a fluoride-containing compound and a surfactant to form the protective coating.
US09982154B2 Solid ink composition
The present invention provides an ink composition. The composition comprises a metal ion and a ligand. The ink composition is in a form of solid at a temperature of less than about 30° C. and in a form of liquid at temperature of above about 40 to about 80° C.
US09982145B2 Self-healing polymer compositions
This invention pertains to a composition that can be used to heal cracks in plastics and other substrates. In the present invention, a composition comprising nanotubes, healing agent(s), and end caps for the nanotubes may be used to heal crack(s) as they begin to occur. With the composition, the healing agent(s) are contained within the nanotubes, and a reaction releases the healing agent(s) after the end caps can be removed from the nanotubes. This invention also includes a method of preparing a composition for healing cracks in plastics and other substrates. For this method, the healing agent(s) are filled inside of the nanotubes, and then end caps are bound onto the ends of the nanotubes. After a reaction occurs to remove the end caps and release the healing agent(s), the cracks within the substrate may then be healed.
US09982143B2 Methods and apparatus for stabilization of surfaces
Various embodiments provide surface compositions and methods for durable and/or load-bearing surfaces in a variety of industrial, animal, and marine applications. Compositions and methods may comprise utilizing a liquid binder, catalyst, primer, and/or antimicrobial composition to provide durable, waterproof, and/or long-lasting surface compositions to dispose within the roadway voids and/or to create a durable, sanitary surface. The surface compositions may cure rapidly through an internal exothermic reaction process to form the repair and/or the safety flooring. The surface composition may be substantially impermeable to animal waste and resistant to harboring agents of disease. In some embodiments, a filler materials may be disposed within the liquid binders to provide elasticity, compression, slip resistance, heat transfer, reduced cure time, and/or a desired surface texture to the surface composition.
US09982142B2 Zinc-rich epoxy anti-corrosion coating and preparation method thereof
This invention relates to a zinc-rich epoxy anti-corrosion coating comprising a component A capable of being cured into a film, and a component B containing a curing agent, wherein the component A comprises, by mass percentage, 0.1-5 wt % graphene, 0-35 wt % zinc powder, 30-70 wt % filler, 10-20 wt % epoxy resin having 54 wt % solid content, and 10-20 wt % solvent, wherein the sum of the mass percentage contents of the graphene, zinc powder and filler is 60-80 wt % and the sum of the mass percentage contents of all components of component A is 100 wt %. According to the present invention, the addition of graphene to an anti-corrosion coating decreases the thickness of the coating film, reduces the amount of zinc powder while increases the anti-corrosion effect. It reduces zinc oxide vapour generated during welding and is environmentally friendly.
US09982141B2 Corrosion resistant coating composition of Ni and a phosphate corrosion inhibitor and an electrodeposition method for the manufacture thereof
A corrosion resistant coating composition for a metal substrate is disclosed. The metal substrate, such as carbon steel, is coated with a first layer comprising a phosphate corrosion inhibitor, such as sodium phosphate monobasic (NaH2PO4) and a second layer comprising nickel nanoparticles. In addition, an electrodeposition method for the production of the coating composition is disclosed that uses either pulse or direct current electrodeposition to form the coating composition of desired anticorrosive properties. In addition, a coated metal substrate and method for inhibiting corrosion of a metal substrate that apply the corrosion resistant coating composition in any of its embodiments are disclosed.
US09982135B2 Polymer-bitumen primary mixtures that can be used for preparing polymer-bitumen binders, and products obtained from these primary mixtures
The aim of the invention is to provide, at a lower cost, novel primary mixtures that can be used for preparing polymer bitumens. For this purpose, the primary mixture according to the invention comprises: (a) at least 25% by weight, preferably 25 to 80% by weight, of polymer, (b) at least one thermoplastic tackifying resin having an average molecular mass of 100 to 3,000 g/mol, (c) and/or one or more mono-alkyl—preferably methyl—esters of fatty acids at C16-C18, in particular sunflower oil, linseed oil, rapeseed oil, soybean oil, and/or sunflower oil that is optionally isomerized; the ester (c) necessarily being present when the tackifying resin (b) has an acid value measured according to standard NF EN ISO 660 of less than 50 mg KOH/g. The invention also concerns the polymer bitumens, emulsions and coatings/coated products obtained from this primary mixture, as well as the methods for preparing same.
US09982134B2 Cross-linkable mixtures having alpha-functional polysiloxanes
Vulcanizates produced by crosslinking of mixtures including alpha-functional polysiloxanes have high relative permittivities at high electric breakdown strengths which renders them suitable as a dielectric material for applications in actuators, generators or sensors in robotics, orthopedics, electrically controllable “artificial muscles,” and transducers producing electricity from kinetic energy.
US09982133B2 Polyamide composition
The invention pertains to a filled polyamide composition [composition (C)] comprising: —from 35 to 80% wt of at least one polyhydric alcohol-modified polyamide, comprising an amount of polyhydric alcohol (PHA, herein after) residues chemically bonded at least to a part of the polyamide [polyamide (A)] of at least 0.1% wt (based on the total weight of polyamide (A)); —from 10 to 65% wt of at least one filler [filler (F)]; —from 1 to 10% wt of at least one impact modifying rubber [rubber (I)]; and —from 0.01 to 3% wt of at least one copper-containing stabilizer, with above % wt being referred to the total weight of composition (C).
US09982132B2 Alloy comprising polyolefin and thermoplastic polyurethane
This invention relates to an alloy comprising polyurethane and polyolefin. It has now surprisingly been found that a specific composition of polyolefin and polyurethane has surprising mechanical properties and at the same time has transparent characteristics and/or appearance. The present invention provides an alloy with remarkable mechanical properties. The phases do not macro-phase separate. Thus, this stable and potentially broad interface is very effective in stress transfer when the alloy is strained. As one might expect, the hardness values for the alloys are in between the hardness values of each component but the other physical properties are no adjusted. In this way, when considering the hardness and mechanical values, these alloys behave like two compatible polymers.
US09982131B2 Automobile interior component formed of reinforced polyphenylene ether-based resin composition
This disclosure is to provide an automobile interior component formed of a reinforced polyphenylene ether-based resin composition, which is excellent in both urethane adhesion and in appearance after molding, mechanical properties such as tensile strength, bending strength and the like, and resident molding stability; and further has sufficient molding fluidity. Provided is an automobile interior component formed of a reinforced polyphenylene ether-based resin composition, containing a polyphenylene ether (A) whereof the reduced viscosity (chloroform solvent, measured at 30° C.) in the molded product is 0.30 to 0.45 dl/g, a styrene resin (B) and a glass fiber (C), where the content of the component (A) is 10 to 30 mass %, the content of the component (B) is 40 to 85 mass %, and the content of the component (C) is 5 to 30 mass % with respect to 100 mass % in total of the components (A) to (C).
US09982130B2 Thermoplastic compositions, methods of their manufacture, and articles thereof
A thermoplastic composition comprises, based on the total weight of the polymers in the thermoplastic composition, a polycarbonatesiloxane-arylate; 2 to 15 wt % or 2 to 8 wt % or 1 to 4 wt % of a core-shell impact modifier; a flame retardant comprising a bromine-containing polymer or oligomer effective to provide 1.5 wt % to 5 wt % of bromine; an aromatic organophosphorus compound, effective to provide 0.1 to 1 wt % of phosphorus, or a combination comprising at least one of the foregoing; and optionally 0 to 80 wt % or 0 to 60 wt % of a polyetherimide.
US09982129B2 Polycarbonate resin composition, and optical material and optical lens each manufactured using same
A polycarbonate resin composition including: a polycarbonate resin (A) which has a constitutional unit (a) represented by general formula (4); and a polycarbonate resin (B) which has a constitutional unit (b) represented by general formula (5). (In formula (4), X represents an alkylene group having 1 to 4 carbon atoms.) (In formula (5), R1 and R2 independently represent a hydrogen atom, an alkyl group having 1 to 20 carbon atoms, an alkoxyl group having 1 to 20 carbon atoms, a cycloalkyl group having 5 to 20 carbon atoms, a cycloalkoxyl group having 5 to 20 carbon atoms, an aryl group having 6 to 20 carbon atoms, or an aryloxy group having 6 to 20 carbon atoms; and Y represents an alkylene group having 1 to 4 carbon atoms.)
US09982113B2 Additive for LDS plastics
The present invention relates to an LDS-active additive for LDS plastics, to a polymer composition comprising an additive of this type, and to an article having metallized conductor tracks in which a polymeric basic body of the article or a polymeric coating on a basic body comprises an LDS additive of the said type.
US09982112B2 Copolymeric polyphosphite polymer stabilizers
A copolymeric polyphosphite is described: wherein each R1 through R5 can be the same or different and independently selected from the group consisting of C12-20 alkyl, C12-22 alkenyl, C12-40 cycloalkyl, C12-40-cycloalkenyl, C12-20 alkyl glycol ethers and A-OH and B—OH are different end-capping groups and independently selected from the group consisting of C2-40 alkylene, C7-40 cycloalkylene, C3-20 alkyl glycol ethers, C3-40 alkyl lactone, and —R7—N(R8)—R9—; wherein R7 and through R9 are independently selected from the group C1-20 alkyl, C2-22 alkenyl, C6-40 cycloalkyl, C7-40 cycloalkylene and H; m and n are integers from 1 to 100 inclusive, with various provisos.
US09982110B2 Water-absorbing resin crosslinking agent
The present invention aims to provide a water-absorbing resin crosslinking agent which is excellent in safety and which can effectively crosslink a water-absorbing resin at low temperatures to produce a water-absorbing agent having a high water absorption capacity. The present invention also aims to provide a water-absorbing agent produced by crosslinking a water-absorbing resin with the water-absorbing resin crosslinking agent, and a method for producing the water-absorbing agent. The present invention may include a water-absorbing resin crosslinking agent containing a halohydrin compound having one halohydrin group represented by the following formula (1) in its molecule: wherein A represents a single bond or an alkylene group; R1 represents a hydrogen atom or an alkyl group; and X represents a chlorine atom or a bromine atom.
US09982107B1 Method of devulcanization of sulfur-cured rubber
This invention relates to a composition for devulcanization of sulfur-cured rubber and a method of devulcanization of sulfur-cured rubber, and can be used to recycle used rubber articles. The composition for devulcanization of sulfur-cured rubber, which contains a devulcanizing agent for the selective destruction of sulfide bonds according to this invention, has a mixture of triphenylphosphine and 1,8-diazabicyclo[5.4.0]undec-7-ene at a weight ratio from 5:1 to 1:5 as the devulcanizing agent. Further, it contains a compatibilizer compatible with both the devulcanizing agent and the sulfur-cured rubber, at a weight ratio of the devulcanizing agent to the compatibilizer from 1:15 to 1:70. The devulcanizing agent breaks sulfide bonds in sulfur-cured rubber very effectively and selectively, while the experimentally selected compatibilizer ensures an effective penetration of the devulcanizing agent into the rubber crumbs. As a consequence, the required concentration of the devulcanizing agent in the resulting compounded rubber does not exceed 1% (preferably, 0.03-0.3%).
US09982106B2 Porous resin particles, method of manufacturing porous resin particles, dispersion liquid, and use of porous resin particles
Disclosed are porous resin particles which contain a polymer of a monomer mixture of a mono(meth)acrylate-based monomer and a polyfunctional vinyl-based monomer. The mono(meth)acrylate-based monomer contains an ethylenic unsaturated group only in a (meth)acrylic acid residue, a hydroxyl group in an alcohol residue, and at least one of an ether group and an ester group in an alcohol residue. The polyfunctional vinyl-based monomer contains two or more ethylenic unsaturated groups. The porous resin particles have a water absorption value of from more than 400 ml to 700 ml per 100 g of the particles and an oil absorption value of from more than 400 ml to 700 ml per 100 g of the particles.
US09982105B2 Surface modification method and surface-modified elastic body
Provided are methods for surface-modifying a rubber vulcanizate or a thermoplastic elastomer, which can cost-effectively provide a variety of functions, e.g. sliding properties or liquid leakage resistance. Included is a method for surface-modifying a rubber vulcanizate or a thermoplastic elastomer as a modification target, the method including: step 1 of forming polymerization initiation points A on a surface of the modification target; step 2 of radically polymerizing a non-functional monomer starting from the points A to grow non-functional polymer chains; and step 3 of forming polymerization initiation points B on a surface of the non-functional polymer chains, radically polymerizing a polymerizable silane compound starting from the points B, and further reacting a perfluoroether group-containing silane compound to grow functional polymer chains, or step 3′ of adding a silane compound to a surface of the non-functional polymer chains and further reacting a perfluoroether group-containing silane compound to grow functional polymer chains.
US09982101B2 Method to fuse silicone and thermoplastic resin
This invention discloses a method to fuse silicone and thermoplastic resin, comprising the following steps: Step A: conducting treatment twice on thermoplastic resin lid upon molding in plasma equipment under normal temperature, and opening the inert molecular chain of thermoplastic resin; wherein the power for treating the thermoplastic resin lid ranges 500 to 800 W, the time of treatment ranges from 5 s to 60 s; Step B: applying glue on the place for laying silicone gasket on thermoplastic resin lid, baking in the oven for 15-20 min; Step C: putting the treated thermoplastic resin lid and silicone gasket in step B into the over mold for encapsulation, the time of which is 2-3 min; conducting post vulcanization for 2 h after completing the encapsulation.
US09982097B2 Thin film self assembly of topcoat-free silicon-containing diblock copolymers
A high-chi diblock copolymer (BCP) for self-assembly comprises a first block comprising repeat units of trimethylsilyl styrene (TMSS) and styrene, and a second block comprising an aliphatic carbonate repeat unit. The blocks are linked together by a fluorinated junction group L′ in which none of the fluorines of L′ are covalently bound to an atomic center of the polymer backbone. A top-coat free film layer comprising the BCP, which is disposed on an underlayer and in contact with an atmosphere, is capable of forming a perpendicularly oriented lamellar domain pattern on an underlayer that is preferential or non-preferential to the domains of the block copolymer. The domain pattern can be selectively etched to provide a relief pattern comprising a remaining domain. The relief pattern having good critical dimensional uniformity compared to an otherwise identical polymer lacking the silicon.
US09982092B1 Supercritical carbon dioxide morphologically modified acid-based halloysite catalyst
The efficient production of poly(tetramethylene ether) diacetate [PTMEA] or other diesters, from tetrahydrofuran [THF] is obtained utilizing an acid-based catalyst that is based on a morphologically reconfigured and Bronsted acidity enhanced halloysite derived from a preparation method of using naturally occurring halloysites. More specifically, the method relates to morphological modification of the internal pore structure of halloysites via supercritical carbon dioxide treatment directly applied onto the raw halloysite minerals, that yields highly synergistic and reproducible results of elimination of inaccessible and detrimental extra-small pores. PTMEA is readily converted to poly(tetramethylene ether) glycol (PTMEG) by a transesterification reaction.
US09982091B2 Highly fluorinated elastomers
Described herein is a peroxide curable, highly fluorinated elastomer derived from (a) a fluorinated di-iodo ether compound of the following formula I: Rf—CF(I)—(CX2)n—(CX2CXR)m—O—R″f-Ok—(CXR′CX2)p—(CX2)q—CF(I)—R′f wherein X is independently selected from F, H, and Cl; Rf and R′f are independently selected from F and a monovalent perfluoroalkane having 1-3 carbons; R is F, or a partially fluorinated or perfluorinated alkane comprising 1-3 carbons; R″f is a divalent fluoroalkylene having 1-5 carbons or a divalent fluorinated alkylene ether having 1-8 carbons and at least one ether linkage; k is 0 or 1; and n, m, and p are independently selected from an integer from 0-5, with the proviso that when k is 0, n+m is at least 1 and p+q is at least 1; and (b) a fluorinated monomer.
US09982089B2 Method of manufacturing polyester resins
The subject of the invention is a method to manufacture polyester resins using a by-product formed during a process of oxidizing cyclohexane to cyclohexanol and cyclohexanone, which contains a mixture of carboxyl acids; the method comprises a heating process with the removal of water and low-boiling residues as well as a polycondensation process with di- and polyhydroxy alcohols under a reduced pressure; the method described is characterized by that a water layer is applied as a baseline material in the synthesis; the said water layer is separated from the residues left over after the hydrolysis of cyclohexyl esters contained in the cyclohexane oxidation product, and after the main components, cyclohexanol and cyclohexanon, have been first separated from the said product: thereafter, the water layer is condensed.
US09982084B2 Surface treatment composition
A composition including a compound containing a carbon-carbon double bond obtained by reacting (A) a polyisocyanate which is a trimer of diisocyanate, with (B) a compound having an active hydrogen, wherein component (B) includes: (B1) a perfluoropolyether having an active hydrogen, (B2) a silane compound having an active hydrogen, and (B3) a monomer having an active hydrogen and a carbon-carbon double bond. Further, a molar amount of an isocyanate group in component (A) is equal to a total molar amount of component (B), and a molar amount of component (B1), component (B2) and component (B3) per 9 moles of the isocyanate group in component (A) are component (B1) 0.1-2 moles, component (B2) 0.05-2 moles, and component (B3) 5-8.85 moles, respectively.
US09982081B2 Cyclic olefin copolymers and methods of making them
A process for making a branched cyclic olefin copolymer (bCOC), and the bCOC therefrom, comprising combining at a temperature within a range from 60° C. to 140° C. a catalyst precursor and an activator with a feed comprising ethylene and at least one cyclic olefin; where the catalyst precursor is selected from the group consisting of CS-symmetric Group 4 metallocenes comprising any two ligands selected from cyclopentadienyl and ligands isolobal to the cyclopentadienyl group. The resulting bCOC is desirably semi-crystalline and useful in such articles as tubing, thermoformed and foamed articles.
US09982079B2 Fluorine-containing polymer composition
Described herein is polymer melt additive composition for use as a processing aid in the extrusion of a non-fluorinated polymer, the polymer melt additive composition comprising a fluorine-containing polymer derived from the polymerization of a monomer and a sulfinate-containing molecule, wherein the sulfinate-containing molecule is selected from the group consisting of: (a) CX1X3═CX2—(R)p—CZ1Z2—SO2M  Formula (I) (b)  and (c) combinations thereof, wherein X1, X2, and X3 are each independently selected from H, F, Cl, a C1 to C4 alkyl group, and a C1 to C4 fluorinated alkyl group; R is a linking group; Z1 and Z2 are independently selected from F, CF3, and a perfluoroalkyl group; R1 and R2 are end-groups; p is 0 or 1; m is at least 2; and M is a cation.
US09982067B2 Polymerization process using pyridyldiamido compounds supported on organoaluminum treated layered silicate supports
This invention relates to a process to polymerize olefins comprising: i) contacting one or more olefins with a catalyst system comprising: 1) a support comprising an organoaluminum treated layered silicate and an inorganic oxide; and 2) a pyridyldiamido compound; and ii) obtaining olefin polymer having high molecular weight and layered silicate dispersed therein. Preferably the support is in the form of spheroidal particles.
US09982066B2 Method for purifying contaminated polymers
A method for purifying a reclaimed polymer, such as a polymer reclaimed from post-consumer use or post-industrial use, is disclosed. The method involves obtaining the reclaimed polymer and contacting it at an elevated temperature and pressure with a fluid solvent to produce an extracted reclaimed polymer. The extracted reclaimed polymer is dissolved in a solvent at an elevated temperature and pressure to produce a polymer solution, which is purified at an elevated temperature and pressure by contacting the polymer solution with solid media to produce a purer polymer solution. A purer polymer is then separated from the purer polymer solution.
US09982064B2 Process for preparing an inhibited starch
The present invention provides a process for preparing an inhibited starch comprising, in order: a) extracting starch from a native source and partially refining to provide a partially refined starch having a residual protein content on a dry starch basis of more than 0.4% by weight and less than 8.0% by weight; b) treating said partially refined starch with a bleaching agent to provide an inhibited starch; and c) recovering said inhibited starch.
US09982061B2 Antibodies to ticagrelor and methods of use
The disclosure generally provides antibodies and antigen binding fragments of antibodies that bind ticagrelor and metabolites of ticagrelor. The disclosure also provides compositions comprising the antibodies, nucleic acid molecules encoding the antibodies, methods of treating a patient comprising administering the antibodies, and methods of making and using the antibodies.
US09982053B2 Immunological reagents
This disclosure relates to binding agents with specificity for programmed cell death 1 (PD-1) and to methods for using the same to treat, prevent and/or ameliorate an infectious disease (e.g., human immunodeficiency virus (HIV)), cancer and/or autoimmunity.
US09982048B2 Reducing systemic regulatory T cell levels or activity for treatment of Alzheimer's disease
A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a disease, disorder, condition or injury of the CNS that does not include the autoimmune neuroinflammatory disease, relapsing-remitting multiple sclerosis (RRMS), is provided. The pharmaceutical composition is for administration by a dosage regimen comprising at least two courses of therapy, each course of therapy comprising in sequence a treatment session followed by an interval session.
US09982047B2 Reducing systemic regulatory T cell levels or activity for treatment of Alzheimer's disease
A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a disease, disorder, condition or injury of the CNS that does not include the autoimmune neuroinflammatory disease, relapsing-remitting multiple sclerosis (RRMS), is provided. The pharmaceutical composition is for administration by a dosage regimen comprising at least two courses of therapy, each course of therapy comprising in sequence a treatment session followed by an interval session.
US09982046B2 Methods of treating cardiovascular disorders with lectin-like oxidized LDL receptor 1 antibodies
The present invention relates to monoclonal antibodies binding to human lectin-like oxidized LDL (low density lipoprotein) receptor 1 (hereinafter, sometimes referred to as “LOX-1”), and pharmaceutical compositions and methods of treatment comprising the same.
US09982038B2 Antibodies against F glycoprotein of Hendra and Nipah viruses
The present invention relates to antibodies or antibody fragments that bind, neutralize, and/or inhibit Hendra or Nipah virus. The invention provides antibodies or antibody fragments that selectively bind to the F glycoprotein of Hendra or Nipah virus, and pharmaceutical compositions including such antibodies and/or fragments. The invention further provides polynucleotides encoding the antibodies and fragments of the invention and host cells transformed therewith. Additionally, the invention discloses prophylactic, therapeutic, and diagnostic methods employing the antibodies, fragments, polynucleotides, and/or compositions of the invention.
US09982036B2 Dual FC antigen binding proteins
The present invention relates to antigen binding proteins comprising two Fc parts, methods for their production, pharmaceutical compositions containing said antigen binding proteins, and uses thereof.
US09982034B2 Platelet targeted treatment
The present disclosure relates to compositions and methods for targeting expression of exogenous genes to platelets. In particular, the present disclosure relates to treatment of hemophilia and other diseases and conditions by targeting expression of exogenous agents (e.g., clotting factors) to platelets.
US09982032B2 Stable liquid formulation of fusion protein with IgG Fc domain
A stable liquid formulation includes a fusion protein having an Fc domain of a human immunoglobulin G (IgG), in particular, a protein in which an Fc domain of a human immunoglobulin G (IgG) and a soluble extracellular domain of a vascular endothelial growth factor (VEGF) receptor are fused (e.g., aflibercept)). A composition for stabilizing a protein and a method for stabilizing a protein in which an Fc domain of an IgG and a soluble extracellular domain of a VEGF receptor are fused are disclosed. The present invention improves therapeutic effects on various ophthalmic diseases (e.g., retinal vein occlusion, diabetic macular edema, choroidal neovascularization and wet age-related macular degeneration, etc.) caused by abnormal angiogenesis, while pursuing stabilization of bioactivity through a stable liquid formulation suitable for intravitreal injection of an anti-VEGF-Fc fusion protein including aflibercept.
US09982020B2 Antiviral compounds and methods for treating infections caused by double-stranded DNA viruses
The present invention relates to polyamide compounds and their use in pharmaceutical compositions and in medical applications for the treatment of human papillomavirus infections and/or polyomavirus infections.
US09982019B2 Glycopeptide compound or pharmaceutical salt thereof and method for preparing same, and pharmaceutical compositions and applications thereof
The present invention provides a glycopeptide compound or pharmaceutically acceptable salt thereof as shown in Formula (I) or (II), and a method for preparing same, and pharmaceutical compositions and applications thereof, wherein the definition of R1, R2, R3, R4, R5 is the same as that of the specification. The glycopeptide compound of the present invention has in-vitro antibacterial activity and has important significance for development of new antibacterial agents.
US09982018B2 Amatoxin derivatives
The invention relates to tumor therapy. In one aspect, the present invention relates to conjugates of an amatoxin and a target-binding moiety, e.g. an antibody, connected by certain linkages, which are useful in the treatment of cancer and other disorders and diseases. In a further aspect the invention relates to pharmaceutical compositions comprising such conjugates.
US09982015B2 Cyclin based inhibitors of CDK2 and CDK4
Structural and functional analysis of peptide inhibitor binding to the cyclin D and cyclin A groove has been investigated and used to design peptides that provide the basis for structure-activity relationships, have improved binding and have potential for development as chemical biology probes, as potential diagnostics and as therapeutics in the treatment of proliferative diseases including cancer and inflammation.
US09982014B2 Tetrapeptide compound and method for producing same
The present invention is to provide a method for the efficient production on an industrial scale of SS-31 (D-Arg-Dmt-Lys-Phe-NH2), which is an SS peptide. According to the present invention, the desired SS-31 is produced by efficiently synthesizing a tetrapeptide compound as a precursor of SS-31 and improving the tetrapeptide purity by crystallization.
US09982013B2 Readily isolated bispecific antibodies with native immunoglobulin format
A bispecific antibody format providing ease of isolation is provided, comprising immunoglobulin heavy chain variable domains that are differentially modified in the CH3 domain, wherein the differential modifications are non-immunogenic or substantially non-immunogenic with respect to the CH3 modifications, and at least one of the modifications results in a differential affinity for the bispecific antibody for an affinity reagent such as Protein A, and the bispecific antibody is isolable from a disrupted cell, from medium, or from a mixture of antibodies based on its affinity for Protein A.
US09982008B2 Preparation and uses of obeticholic acid
The present invention relates to obeticholic acid: or a pharmaceutically acceptable salt, solvate or amino acid conjugate thereof. Obeticholic acid is useful for the treatment or prevention of a FXR mediated disease or condition, cardiovascular disease or cholestatic liver disease, and for reducing HDL cholesterol, for lowering triglycerides in a mammal, or for inhibition of fibrosis. The present invention also relates to processes for the synthesis of obeticholic acid.
US09982004B2 Method for recovering low molecular weight lignin from a filtrate
The invention relates to a method for recovering low molecular weight lignin from a filtrate, wherein the low molecular weight lignin includes lignin molecules having a molecular weight of 3000 g/mol or lower, wherein the filtrate is obtained from a process where lignin is precipitated from black liquor and the formed precipitate is separated therefrom by filtration resulting in the filtrate including low molecular weight lignin being formed, and wherein the method includes the following steps: a) adjusting the pH of the filtrate to a value of 3-4 for precipitating lignin in the filtrate; b) separating the precipitated lignin from the filtrate; c) reslurrying the separated lignin until the dry solids content of the slurry is 25-40 weight-% and adjusting the pH of the slurry to a value of 2-3; d) washing the slurry; and e) separating the lignin from the slurry.
US09982003B2 Group 3 metal catalyst system and process to produce ethylene polymers therewith
This invention relates to a process to using dimers of a group 3 metal (typically scandium) catalyst compound to produce ethylene polymers, such as ethylene-alpha-olefin copolymers and ethylene-conjugated diene copolymers.
US09982000B2 Pyrazole compounds and method for making and using the compounds
Disclosed embodiments concern novel interleukin receptor associated kinases (IRAK) inhibitors and compositions comprising such inhibitors. Also disclosed are methods of making and using the compounds and compositions. The disclosed compounds and/or compositions may be used to treat or prevent an IRAK-associated disease or condition.
US09981999B2 Neprilysin inhibitors
In one aspect, the invention relates to compounds having the formula X: where Ra, Rb, R2, R7, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds described herein are prodrugs of compounds having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.
US09981995B2 Azocarbonyl-functionalized silanes
Azocarbonyl-functionalized silanes of formula I (R1)3-a(R2)aSi—R1—NH—C(O)—N═N—R4  (I) and methods for their production are provided. The silanes of formula (I) are useful in rubber mixtures to provide moldings having improved tear-resistance.
US09981992B2 Compositions and methods for reduction of ketones, aldehydes and iminiums, and products produced thereby
A method of producing an alcohol, comprises reducing an aldehyde or a ketone with a hydridosilatrane. The reducing is carried out with an activator.
US09981988B2 Polymorphic forms and co-crystals of a c-Met inhibitor
Provided herein are novel polymorphic forms and co-crystals of a compound useful in the treatment, prevention, or amelioration of cancer. In particular, the invention provides polymorphs and co-crystals of 6-{(1R)-1-[8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one, which is an inhibitor of c-Met.
US09981982B2 Superoleophobic and/or superhydrophobic material, process for preparing same and applications thereof
The invention relates to a multilayer superoleophobic and/or superhydrophobic material comprising: ⋅ on the one hand, a first constituent that is a conductive substrate or a substrate that has previously been rendered conductive (1): ⋅ the surface of which is modified by chemical and/or physical treatment (2) and that incorporates a first adhesion-promoting conductive layer (3); ⋅ or that incorporates a first adhesion-promoting conductive layer (3); ⋅ and, on the other hand, at least one other constituent that is a superoleophobic and/or superhydrophobic polymer or copolymer layer (4, 5 or 6) composed of one or more monomers based on an aromatic or heteroaromatic ring substituted by one or more fluorocarbon and/or hydrocarbon chains. It is characterized in that the various constituents of said material comply with an increasing hydrophobicity gradient between the first layer deposited on the conductive substrate or substrate previously rendered conductive (1) and the last layer of said material.
US09981980B2 1,5-Disubstituted 1,2,3-triazoles are inhibitors of Rac/Cdc42 GTPases
Compounds are disclosed that inhibit RhoGTPases that are useful for inhibiting hyperprofilerative and neoplastic diseases. Specifically, the compounds inhibit the GTPases Rac and Cdc42 that are overactive or overexpressed in signaling pathways in cancer and metastasis. Methods for treatment of cancer and hyperproliferative diseases are disclosed.
US09981976B2 Piperidine substituted pyrazolo[1,5-A]pyrimidine derivatives with inhibitory activity on the replication of the respiratory syncytial virus (RSV)
The invention concerns novel substituted bicyclic pyrazolo pyrimidine compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection.
US09981974B2 Small molecules targeting androgen receptor nuclear localization and/or level in prostate cancer
A method for treating prostate cancer in a subject, comprising administering a therapeutically effective amount of at least one agent to the subject, wherein the agent is selected from: (a) a phenyl-substituted imidazole, or a pharmaceutically acceptable salt or ester thereof; or (b) a compound, or a pharmaceutically acceptable salt or ester thereof, having a formula I of: wherein R20 is an aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycloalkyl, substituted heterocycloalkyl, alkoxy, aryloxy, a silyl-containing group, a boryl-containing group, a phosphine-containing group, amino, a thio-containing group, a seleno-containing group, halide, or a nitro-containing group; R21 is an alkanediyl or a substituted alkanediyl; a is 0 or 1; c is 0 or 1; X is C or S; R22 is a moiety that includes at least one divalent amino radical; and R23 is an aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycloalkyl, substituted heterocycloalkyl, alkoxy, aryloxy, a silyl-containing group, a boryl-containing group, a phosphine-containing group, amino, a thio-containing group, a seleno-containing group, halide, or a nitro-containing group.
US09981969B2 Imidazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug
The present invention relates to Imidazole Derivatives of Formula (I), and pharmaceutically acceptable salts thereof, wherein A, B, Y, R1 and R2 are as defined herein. The present invention also relates to compositions comprising at least one Imidazole Derivative, and methods of using the Imidazole Derivatives for inhibiting CYP450 3A. Inhibition of CYP450 3A can be used to improve the pharmacokinetics of a drug that is metabolized by CYP450 3A4.
US09981968B2 Substituted pyrrolo[2,3-d]pyrimidines for the treatment of cancer and proliferative disorders
Disclosed are substituted pyrrolo[2,3-d]pyrimidine compounds. The disclosed compounds are shown to be useful in inhibiting the growth of cancer cell lines and treating cancer and cell proliferative disorders and have a general Formula I as indicated:
US09981967B2 Synthesis of imidazo[1,2-a]pyrazin-4-ium salts for the synthesis of 1,4,7-triazacyclononane (tacn) and N- and/or C-functionalized derivatives thereof
The present invention embodiments relate to a compound with formula (V′) The invention also relates in certain embodiments to the synthesis method for compound (V′) and its use for the preparation of 1,4,7-triazacyclononane (tacn) and N- and/or C-functionalized derivatives thereof, particularly compounds with formula (I) The invention also relates in certain embodiments to metallic complexes comprising a ligand with formula (I) and a metal and their use for imaging.
US09981965B2 Process for preparing idelalisib
The present invention relates to an improved process for preparing Idelalisib (1). In this process, acid addition salts of idelalisamine (2) are useful intermediates for purification purposes.
US09981963B2 3-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-c]pyridine derivatives as NIK inhibitors
The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of NF-κB-inducing kinase (NIK—also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders.
US09981960B2 Pyrrolidine compound and application as melanocortin receptor agonist
The present invention relates to a novel pyrrolidine compound having melanocortin receptor agonist activity or a pharmaceutically acceptable salt thereof, and to pharmaceutical applications thereof. The present invention relates to a pyrrolidine derivative represented by formula [I], wherein ring A represents an optionally substituted aryl group or the like; R1 represents an optionally substituted alkyl group or the like; R2 represents a halogen atom or the like; and R3 is an alkyl group substituted with an optionally substituted aryl group or the like, and R4 is a hydrogen atom or the like; or R3 and R4 are terminally attached to each other, and together with the nitrogen atom to which they are attached, form an optionally substituted nitrogen-containing aliphatic heterocyclic ring that may partially contain a double bond; or to a pharmaceutically acceptable salt thereof.
US09981956B2 Small molecule inhibitors of fibrosis
Described herein are compounds and compositions for the treatment of a fibrotic disease.
US09981955B2 Antiviral compounds
The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
US09981953B1 Contrast agent precursor and method for preparing the same
A contrast agent precursor is revealed. The contrast agent precursor includes a 1,4,7-Tris(carbonylmethyl)-1,4,7,10-tetraazacyclododecane that forms complexes with radioisotopes or connects to a peptide. The contrast agent precursor also includes a 2-nitroimidazole that allows the precursor to become retained in hypoxic tissues According to the features mentioned above, the contrast agent prepared by the precursor has a better binding specificity, labeling accuracy and detection sensitivity. Moreover, a method for preparing the contrast agent precursor not only solves the emulsion problem generated during conventional synthesis of intermediate products but also provides a solution to the problem of residual trifluoroacetic acid. Both the yield rate and the purity of the final product are also improved.
US09981952B2 Oxazetidine derivatives, process for preparing them and use in human medicine and in cosmetics
Compounds that are agonists of the MCIR receptor and that exhibit reduced toxicity relative to other compounds of the same class are described. These compounds can have the general formula (I) wherein: R1 represents a cyclopropylmethyl or a 4-hydroxybutyl group; R2 represents a hydrogen atom or a methyl group; and also the salts and enantiomers of the corresponding compounds of general formula (I). Also described, are methods for treating hypopigmentary pathologies and photosensitive dermatoses.
US09981943B2 Antifungal compound process
The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
US09981938B2 Quaternary ammonium alkyl esters as stable prodrugs
Disclosed herein are compounds according to Formulas 1-12, compositions comprising these compounds, and methods of lowering intraocular pressure (IOP) or causing hair growth, and methods of using the same.
US09981936B2 Isoflavonoid compositions and methods for the treatment of cancer
Provided herein is a pharmaceutical composition comprising an isoflavonoid derivative and a cyclodextrin. Also provided herein are methods of treating cancer, sensitizing cancer cells, and inducing apoptosis in cancer cells by administering such compositions. In specific instances, provided herein are intravenous compositions and therapies.
US09981933B2 Detergent compositions
A surfactant component comprising a compound of formula (I): (I) wherein R1 is a C5 to C39 alkyl or alkenyl group and R2 is a group of formula (a) wherein one of W, X, Y and Z is a covalent bond and the remaining groups are independently selected from H, M, SO3M and a further group of formula R1CO provided at least one of W, X, Y and Z is SO3M; and each M is independently a hydrogen ion, an ammonium ion or a metal ion.
US09981925B2 Substituted benzo[d][1,2,3]triazines as p70S6K inhibitors
Novel azaquinazoline carboxamide derivatives of formula (I) wherein W1, W2, W3, W4, R1, R2, R3 and m which are defined above, are p70S6K inhibitor, and can be employed, inter alia, for the treatment of hyperproliferative disorders.
US09981924B2 Integrated production of urea and melamine
Disclosed is a process for the integrated production of urea and melamine. A urea production zone produces a urea synthesis stream comprising urea, water and ammonium carbamate. This stream is subjected to processing, preferably involving stripping, so as to separate an aqueous urea stream from residual dissociated carbamate vapor comprising ammonia, carbon dioxide, and water. The urea is fed to a melamine synthesis zone and subjected to melamine forming conditions so as to form melamine and off-gas comprising carbon dioxide and ammonia. The dissociated carbamate vapor and the melamine off-gas are subjected to combined condensation so as to form a dilute melamine off-gas condensate.
US09981918B2 Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
Certain chemical entities are provided herein. Also provided are pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one chemical entity as a single active agent or administering at least one chemical entity in combination with one or more other therapeutic agents. Also provided are methods for screening compounds capable of inhibiting KMO activity.
US09981914B2 Hydrogen barrier agent, hydrogen barrier film forming composition, hydrogen barrier film, method for producing hydrogen barrier film, and electronic element
To provide a hydrogen barrier agent capable of imparting hydrogen barrier performance to various materials; a hydrogen barrier film forming composition including the hydrogen barrier agent; a hydrogen barrier film including the hydrogen barrier agent; a method for producing a hydrogen barrier film, which uses the hydrogen barrier film forming composition; and an electronic element provided with the hydrogen barrier film. A compound having a specific structure including an imidazolyl group is used as the hydrogen barrier agent. Furthermore, the hydrogen barrier film forming composition is prepared by blending the above-mentioned hydrogen barrier agent into the base material component. In addition, the hydrogen barrier film is formed using the hydrogen barrier film forming composition.
US09981913B2 Liver X receptor (LXR) modulators
Described herein are liver X receptor (LXR) modulators and methods of utilizing LXR modulators in the treatment of dermal diseases, disorders or conditions. Also described herein are pharmaceutical compositions containing such compounds.
US09981911B2 Process for the preparation of 4-amino-5-fluoro-3-chloro-6-(substituted)picolinates
4-Amino-5-fluoro-3-chloro-6-(substituted)picolinates are prepared from trifluoroacetic acid, p-methoxyaniline, a 3,3-dialkoxyprop-1-yne and a substituted methylene amine by a series of steps.
US09981910B2 Substituted pyrrolidines and methods of use
The invention discloses compounds of Formula (I) wherein R1, R2, R2A, R3, R3A, R4, R4A, and R5 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
US09981905B2 Aromatic diamine, an intermediate therefor, a method for producing the aromatic diamine, and a method for producing the intermediate therefor
An asymmetric diamine suitable for preparing a soluble polyimide and a method for preparing the same, including a compound represented by the following formula (1): wherein R1, R2, R3 and R4 are, independently of each other, a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or an alkoxy group having 1 to 3 carbon atoms, and A and B are, independently of each other, a nitro group or an amino group. Further, a method for preparing the compound represented by the aforesaid formula (1).
US09981903B2 Method for preparing di- or tricarboxylic esters by alkoxycarbonylation of dienes having conjugated double bonds
The invention relates to a method for preparing di- or tricarboxylic esters by alkoxycarbonylation of dienes having conjugated double bonds. The method includes the steps of initially charging a diene having two conjugated double bonds, adding a phosphine ligand according to formula (I) and a catalyst precursor, adding an alcohol, feeding in CO, and heating the reaction mixture with conversion of the diene to a di- or tricarboxylic ester.
US09981902B2 Process for production of an ester and diol from reclaimed carpet material
The current invention pertains to a process for producing a terephthalate ester comprising: providing reclaimed carpet material comprising a polyester component; and reacting the polyester component with an alcohol having from 6 to 20 carbon atoms and under conditions effective to produce a terephthalate ester; wherein 15-40% of the mass of the terephthalate ester is derived from the polyester present in the reclaimed carpet material.
US09981901B2 IRE-1α inhibitors
Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.
US09981899B2 Composition containing reduced coenzyme Q10 and production method thereof
The present invention provides a particulate composition wherein an oil component containing reduced coenzyme Q10 is polydispersed forming a domain in a matrix containing a water-soluble excipient, which simultaneously shows high oxidative stability and high oral absorbability, a production method thereof, and a stabilizing method thereof. It also provides a food, food with nutrient function claims, food for specified health uses, dietary supplement, nutritional product, animal drug, drink, feed, pet food, cosmetic, pharmaceutical product, therapeutic drug, prophylactic drug and the like, which contain the composition.
US09981896B2 Conversion of methane to dimethyl ether
Herein disclosed is a method of producing dimethyl ether (DME) comprising introducing one or more feed streams comprising methane and carbon dioxide into a reformer to generate synthesis gas; and converting synthesis gas to DME in one step. In some cases, the reformer comprises a Ni catalyst. In some cases, the reformer is a pressurized fluidized bed dry reforming reactor. In some cases, the reformer comprises a hydrogen membrane. The hydrogen membrane removes hydrogen contained in the synthesis gas and shifts reforming reactions toward completion.
US09981888B2 Processes for high severity fluid catalytic cracking systems
Embodiments of methods for converting gas condensate into a product stream comprising propylene comprise feeding gas condensate at a top region of a downflow high severity fluidized catalytic cracking reactor (HSFCC), where the gas condensate comprises: at least 50% by weight paraffins, and less than 0.1% by weight olefins. The method further comprises feeding catalyst to the top region of the downflow HSFCC reactor in an amount characterized by a catalyst to gas condensate weight ratio of about 5:1 to about 40:1, where the catalyst comprises nano-ZSM-5 zeolite catalyst having an average particle diameter from 0.01 to 0.2 μm, a Si/Al molar ratio from 20 to 40, and a surface area of at least 20 cm2/g. The method further comprises cracking the gas condensate in the presence of the catalyst at a reaction temperature of about 500° C. to about 700° C. to produce the product stream comprising propylene.
US09981885B2 Device for producing humus
A device is described for producing humus, in particular a composter, having a compost container (1) forming a jacket, which is closed on top using a cover (2), wherein the cover (2) forms a rainwater collecting basin (3), with which at least one drain (5) opening into the composter interior (4) is associated. To achieve advantageous climate conditions in the composter container, it is proposed that the drain (5) open into a collection container (6) associated with the jacket.
US09981883B2 Dual purpose agricultural compositions
A method of fertilizing a plant comprises applying to a plant an effective amount of a composition comprising a product of a salicylic acid, a potassium polyphosphite, a potassium phosphite, and a potassium phosphate. The composition may be prepared by reacting salicylic acid, ammonium hydroxide, potassium hydroxide and/or potassium carbonate, phosphoric acid, and phosphorous acid.
US09981881B2 Ceramic honeycomb filter and its production method
A ceramic honeycomb filter comprising a ceramic honeycomb structure having pluralities of flow paths partitioned by porous cordierite cell walls, and plugs formed in predetermined flow paths of the ceramic honeycomb structure; the plugs being formed by ceramic particles and an amorphous oxide matrix existing between the ceramic particles; in a cross section of the plugs, an area ratio A1 of the amorphous oxide matrix in a longitudinal range of ⅓×t from one end, and an area ratio A2 of the amorphous oxide matrix in a longitudinal range of ⅓×t from the other end meeting the relation of ½≤A1/A2≤2, wherein t represents the length of the plug in a direction perpendicular to the longitudinal direction of the plug.
US09981877B2 Compositions and methods for plugging honeycomb bodies with reduced plug depth variability
A composition for applying to a honeycomb body includes a refractory filler, an organic binder, an inorganic binder, and a liquid vehicle, wherein the refractory filler, the particle size distribution of the refractory filler, the organic binder, and the inorganic binder are selected such that, when the composition is applied to plug a plurality of channels of the honeycomb body, the plug depth variability is reduced.
US09981871B2 Fabricating highly durable nanostructured coatings on polymer substrate
A method of forming a coating that includes depositing a multicomponent glass layer on a polymer substrate and depositing a heat absorbing layer on the multicomponent glass layer. Inducing spinodal decomposition of the multicomponent glass layer by annealing the heat absorbing layer, and etching at least one of a phase separated component of the multicomponent glass layer. The spinodal decomposition may be achieved through a pulse thermal or electromagnetic assisted annealing process. The coating may then be used as a hydrophilic surface, or may be fluorinated using conventional methods to produce the superhydrophobic coating.
US09981869B2 Gravity bending on a double support
A device for the gravity-bending of a glass sheet, includes a longitudinal roughing mold including two longitudinal roughing supports, and a finishing frame including two lateral finishing supports and two longitudinal finishing supports, the supports forming shaping rails. The distance between middles of the longitudinal finishing supports is shorter than that between middles of the lateral finishing supports. The roughing mold and finishing frame are movable vertically relative to each other during bending to switch from a rough-bending to a final-bending configuration. In the rough-bending configuration, the shaping rails of the longitudinal roughing supports are higher up than those of the longitudinal finishing support. In the final-bending configuration, the shaping rails of the longitudinal finishing supports are higher up than those of the longitudinal roughing supports. The shaping rails of the lateral finishing supports are the only ones under lateral edges of the glass in the roughing and final-bending configurations.
US09981866B2 Fracture water treatment method and system
A method and system for treatment of flow-back and produced water from a hydrocarbon well in which fracturing operations are carried out using a phase separation and creating of positive charge in the water.
US09981862B2 Reactor usable for decontamination of fluids and method of use
The invention relates to a method for the decontamination of contaminated liquid, as well as a reactor for implementing a decontamination method. The method comprises a step of mixing the contaminated liquid under stirring with at least one persulphate ion with the exception of ammonium persulphate, and at least iron, an iron atom or an iron ion in its ferrous or ferric form at a concentration between 50 μM and 600 μM, preferably between 100 μM and 400 μM, a second step in which the mixture obtained is subjected for a sufficient time to at least one UV/visible irradiation having a narrow wavelength spectrum comprised between 153 nm and 560 nm.
US09981861B2 Modified walnut shell and use
Herein are described compositions useful in the purification of hydrocarbon-contaminated liquids (e.g., oil-contaminated water), methods of their manufacture, and methods of their use. In one instance, the composition can include a porous agricultural substrate selected from the group consisting of walnut shell, pecan shell, apricot pit, peach pit, corn cob, and a mixture thereof; the porous agricultural substrate having an external surface and pores, wherein the external surface is hydrophilic; and an organo-amine carried within the pores of the porous agricultural substrate. These compositions are utilized as regenerable filter media in place of, for example, ground walnut media.
US09981858B2 Process for producing hemataite for ironmaking
Proposed is a process for separating a leach residue from which a hematite-containing material that can be used as a raw material for ironmaking can be obtained, and provided is a production process of hematite for ironmaking from the leach residue. The process for producing hematite for ironmaking using, as a raw material, the leach residue in a slurry state obtained from a hydrometallurgical plant for nickel oxide ore utilizing a high pressure acid leach process comprises in sequence: a first step of separating the leach residue in a slurry state into an overflow and an underflow using a wet cyclone; a second step of separating the overflow into a strong magnetic component and a weak magnetic component using a strong-magnetic-field magnetic separator utilizing magnetic force; and a third step of sintering the separated strong magnetic component at a temperature of 1150 to 1350° C. to form a sintered body.
US09981854B2 Process for co-production of ammonia, urea and methanol
A process for co-production of ammonia, urea and methanol from natural gas, comprising the steps of (a) producing a synthesis gas by simultaneous feeding natural gas to an autothermal reformer (ATR) and to a steam methane reformer (SMR), the two reformers running in parallel, (b) feeding air to an air separation unit (ASU), where the air is split into oxygen, which is fed to the ATR, and nitrogen, (c) subjecting the synthesis gas from the SMR to a water gas shift, (d) removing the carbon dioxide from the synthesis gas from step (c) and leading it to urea synthesis in a urea synthesis unit, (e) combining the hydrogen-rich gas from step (d) with the nitrogen from step (b), removing catalyst poisons from the gases and leading the gas mixture to ammonia synthesis in an ammonia synthesis unit, (f) optionally removing part of the carbon dioxide from the syngas from the ATR in step (a) and leading it to urea synthesis in a urea synthesis unit and (g) leading the syngas from step (f) to the methanol synthesis unit, wherein synthesis gas from step (a) may be led either from the ATR outlet to the SMR outlet upstream from the shift stage or the other way.
US09981852B2 Selective sonication-assisted deposition method of inorganic particles and CHA zeolite membranes grown from seeded layers on substrates using the method and plate-like Si-CHA zeolite particles used for seed layer formation and manufacturing method of the same
Provided is a selective sonication-assisted deposition method of inorganic particles and CHA zeolite membranes grown from seeded uniform layers on substrates using the method and plate-like Si-CHA zeolite particles used for seed layer formation and manufacturing method of the same, in which thin inorganic particles may be selectively deposited on a substrate or on a support, and even a physical interaction between the deposited particles and supports (or substrates) alone allows for obtaining high surface coverage to form a uniform layer, which is critical in reproducible production of membranes of inorganic materials, such as zeolite, by secondary growth.
US09981847B2 Facilitated CO2 transport membrane and method for producing same, and method and apparatus for separating CO2
Provided is a facilitated CO2 transport membrane having an improved CO2 permeance and an improved CO2/H2 selectivity. The facilitated CO2 transport membrane includes a separation-functional membrane that includes a hydrophilic polymer gel membrane containing a CO2 carrier and a CO2 hydration catalyst. Further preferably, the CO2 hydration catalyst at least has catalytic activity at a temperature of 100° C. or higher, has a melting point of 200° C. or higher, or is soluble in water.
US09981844B2 Method of manufacturing semiconductor device with glass pieces
A source material, which is based on a glass, is arranged on a working surface of a mold substrate. The mold substrate is made of a single-crystalline material. A cavity is formed in the working surface. The source material is pressed against the mold substrate. During pressing a temperature of the source material and a force exerted on the source material are controlled to fluidify source material. The fluidified source material flows into the cavity. Re-solidified source material forms a glass piece with a protrusion extending into the cavity. After re-solidifying, the glass piece may be bonded to the mold substrate. On the glass piece, protrusions and cavities can be formed with slope angles less than 80 degrees, with different slope angles, with different depths and widths of 10 micrometers and more.
US09981838B2 Drinking water supply device
A drinking water supply device configured to discharge water based on a pressure of water supplied from a water supply source is provided. The drinking water supply device may include at least one discharge flow path that allows water supplied from the water supply source to flow therein, a discharge valve provided in the at least one discharge flow path, at least one cock provided in an end of the at least one discharge valve, the discharge valve including a sensor that generates a discharge signal to open the at least one discharge valve, a lever coupled to the at least one cock and operated by pushing and pulling, and a controller that controls the at least one discharge valve and the sensor. The discharge signal may be generated in the sensor when a switch of the sensor is pressed by a predetermined region of the lever.
US09981834B2 Method of actively controlling winch swing via modulated uptake and release
An unmanned aerial vehicle (UAV) including a winch system, wherein the winch system includes a winch line having a first end that is secured to the payload, and wherein the winch system is controllable to vary the rate of descent of the payload, an inertial measurement unit positioned on the payload or on the first end of the winch line, wherein the inertial measurement unit is configured to measure oscillations of the payload, and a control system configured to (a) receive data from the IMU, (b) determine oscillations of the payload based on the data received from the IMU, and (c) operate the winch system to vary the deployment rate of the winch line so to damp oscillations of the payload.
US09981833B2 Beverage container handling and storage system
A system for handling and storage of beverage containers in a storage space includes a support structure, a hoist motor operably connected to the support structure and movable via the support structure along both a length of the storage space and a width of the storage space, and a lift member operably connected to the hoist motor to secure a first end of a beverage container in an upright position to the hoist motor to lift and move the beverage container from a first location to a second location via operation of the hoist motor and movement of the hoist motor along the support structure.
US09981832B1 Control panel assembly
A control panel assembly for mounting to an interior compartment of a wrecker, the control assembly comprising an extendable arm assembly and a control panel. The extendable arm assembly is mounted to the interior compartment and comprises arms which are foldable relative to each other for adopting a compact configuration and an extended configuration. The control panel is mounted to the extendable arm assembly and comprises wrecker controls. The control panel is movable between an inner position, wherein the extendable arm assembly is in the compact configuration and the wrecker controls are located within the interior compartment, and an outer position, wherein the extendable arm assembly is in the extended configuration and the wrecker controls are located outside the interior compartment.
US09981830B2 Support for an elevator installation
A method of providing a support for an elevator car in an elevator installation, wherein the support includes a plurality of tensile carriers arranged parallel to one another and substantially enclosed by a casing, includes pre-preparation of a first support end wherein the tensile carriers are directly electrically contactable at a pre-prepared location by a contacting device, and wherein the pre-preparation is carried out before transport of the support to the elevator installation.
US09981827B2 Safety brake for an elevator
A safety brake for an elevator includes a brake element or a brake wedge, a guide element, and a setting device. The brake element or the brake wedge is borne movably on the guide element. The safety brake has an activating element, which, upon activation of the safety brake, can be brought into mechanical engagement with the brake element or the brake wedge to act on a guiderail to stop an associated elevator car.
US09981822B2 Flexible tube cleaning lance drive apparatus
A flexible lance drive device is disclosed that has, in a compact housing, a drive motor between an inner and an outer wall, a linear array of pairs of driven upper and lower drive rollers outside the outer wall coupled to the drive motor via shafts extending through both of the inner and outer walls. Each driven roller is fastened to its shaft via a quick release device. A drive sprocket is fastened to each shaft outside the inner wall. The drive motor is coupled to each of the drive sprockets via a serpentine belt carried outside the inner wall. The lower driven rollers are rotatably carried by the inner and outer walls. The upper driven rollers are rotatably carried by a block positioned between the inner and outer walls and coupled to the lower driven rollers by a pair of parallel links releasably biased by a piston driven linkage.
US09981815B2 Transport device
A transport device includes a drive roller and a driven roller. The drive roller transports paper-sheets in a predetermined transport direction by rotation thereof. The driven roller rotates with rotation of the drive roller, and regardless of from which direction the paper-sheets hit a contact point with the first roller, moves in a direction diagonally forward than a vertical direction with respect to the transport direction. The transport device further includes a bearing groove formed so that a shaft of the driven roller moves in a direction diagonally forward than the vertical direction with respect to the transport direction along an inclined surface.
US09981813B2 System and method for monitoring and controlling document velocity in a scanning system
A method of scanning documents and moving such documents along a path such that during scanning a method of improving the documents velocity and the documents image quality is disclosed. The method includes providing a plurality of documents in an input tray and transporting each document along the path from the input tray at a transport velocity past the scanner to obtain scanned image data. By monitoring and controlling the velocity profile of the transport system, the scanning system may provide higher image quality, reduce slippage, misfeeds and jams, and provide alerts to an operator in the even slippage, misfeeds, or jams do occur.
US09981812B2 Automated handling of shipping containers and connectors
An automated method of unloading a shipping vessel includes: receiving a shipping container from the vessel, the container including multiple connectors; retrieving a pallet able to store the connectors, where the pallet includes multiple receptacles, each receptacle able to accommodate one connector; detaching the connectors from the container; transferring the connectors to the pallet; releasing the container; and transferring a subset of the connectors from the pallet to at least one bin that is able to accommodate multiple connectors. An automated method of loading a shipping vessel includes: receiving a shipping container; retrieving a pallet having multiple connectors, where the pallet includes multiple receptacles, each receptacle able to accommodate one connector; retrieving the connectors from the pallet; attaching the connectors to the container; providing the container to the vessel; and transferring a subset of the connectors from the pallet to a bin that is able to accommodate multiple connectors.
US09981811B2 Item movement apparatus
The invention relates to apparatus and a method for the loading of trolley shelves with containers and particularly, although not exclusively, to the loading of trolleys which are known as cage trolleys and which can carry containers which are provided to be removed directly therefrom and purchased, such as containers of milk. The apparatus and method allows loading of groups of containers onto the respective trolley shelves to be performed while the trolleys are retained at a fixed location with respect to the loading apparatus.
US09981810B2 Closed gap transfer for a conveyor and method of using same
A transfer device and method for diverting packages about a conveyor. The conveyor has a conveyor path extending between locations of a facility. The transfer includes a frame positionable about the conveyor, rollers rotationally supported on the frame (the rollers non-aligned with the conveyor path to define a transfer path way from the conveyor path), belts rotationally supported on the frame between the rollers with a closed gap therebetween (the belts aligned with the conveyor path), and a tub movably coupled to the frame to selectively lift the rollers above the belts to engage the packages whereby the packages are selectively movable to locations away from the conveyor path.
US09981809B2 Accumulator device for dynamically accumulating conveyed products, as well as a method for using such a device
An accumulator device includes an infeed conveyor with an endless conveying belt arranged for moving products in a first conveying direction, a substantially parallel outfeed conveyor with an endless conveying belt arranged for moving products in a second, opposing conveying direction, a transfer device provided in-between the infeed and outfeed conveyors, configured for transferring products from the infeed conveyor to the outfeed conveyor. The transfer device is moveable along the infeed and outfeed conveyors, and includes first and second transfer elements with first and second gripping devices for engaging the products and transporting along the transfer trajectory to a release location on the outfeed conveyor.
US09981805B2 Roller track having a profile rail
A roller track for transporting stored goods has a profile rail (1) with a base (11) and two side walls (12) extending at an angle from the base (11). The side walls (12) can pivot onto each other under the influence of a force directed toward the base (11). Roller bodies (2) are supported rotatably about axles (3) in bearing openings (4) of the side walls (12). The bearing openings (4), wherein the bearing openings (4) are designed as countersinks extending from the free end of the sides walls (12) in the direction of the base (12). The roller bodies (2) are inserted into the bearing openings (4) together with the rotating axles (3) substantially in the direction of the side walls (12).
US09981804B2 Drive system for conveyors
A conveyor system includes a drive assembly and a plurality of rollers configured to singulate a plurality of conveyed articles travelling on the plurality of rollers along a direction of travel. Each of the plurality of rollers having a drive end and a base end. The drive end having a drive sheave including a plurality of grooves and a plurality of peaks interposed between the plurality of grooves formed on a surface thereof. The drive assembly is coupled to the drive end of at least one of the plurality of rollers by a drive belt. At least a first portion of the plurality of rollers are disposed at an angle with respect to the direction of travel.
US09981803B2 Refuse vehicle with multi-section refuse ejector
A refuse vehicle includes a chassis, a body, a primary ejector, and an auxiliary ejector. The chassis includes a frame and a cab disposed at one end of the frame. The body includes a hopper portion and a storage portion. The width of the storage portion is greater than the width of the hopper portion. The auxiliary ejector has a width equal to the difference between the width of the storage portion and the width of the hopper portion. The primary ejector is selectively repositionable within the hopper portion and the storage portion of the body to at least one of compact refuse therein or eject refuse therefrom. The auxiliary ejector is selectively repositionable within the storage portion of the body to at least one of compact refuse therein and eject refuse therefrom in tandem with the primary ejector.
US09981797B2 Nested insulated packaging
A nested insulated packaging assembly includes: an outer box including an outer top side wall, an outer bottom side wall, and a plurality of outer lateral side walls; an inner box received in the outer box, the inner box including an inner top side wall, an inner bottom side wall, and a plurality of inner lateral side walls; a first thermal liner contacting a one of the outer lateral side walls of the outer box and a one of the inner lateral side walls of the inner box; and a second thermal liner contacting a second of the outer lateral side walls of the outer box and a second of the inner lateral side walls of the inner box.
US09981795B2 Container for aseptic content
The present invention relates to a container equipped with a closure system particularly adapted for aseptically filled fluid contents. The invention also relates to the use of said container in a method for detecting spoilage of its fluid content.
US09981788B2 Child-resistant package
A child-resistant package comprises a carton and a tray removably slidably receivable in the carton with a releasable locking mechanism. A laterally displaceable locking tab is biased to extend outwardly from the tray, and the carton has an inner wall disposed interiorly of, spaced from and adjacent to an outer wall of the carton. A locking slot is formed in the inner wall for releasably receiving the locking tab and the outer wall has an inwardly depressible button adjacent the inner wall and in registration with the locking slot. When in registration with the locking slot, the locking tab moves into the locking slot, engaging an edge of the locking slot to resist withdrawal of the tray from the carton. Pushing the button inwardly pushes the locking tab out of the locking slot, enabling the locking tab to slide along the inner wall of the carton for withdrawing the tray.
US09981786B2 Method and apparatus for controlled transfer of fluid
Embodiments of the present disclosure generally relate to caps, closures, seals, and containers, and control of flow of fluids. Certain embodiments can be used with fluids related to machinery, for instance, engine oil, brake fluid, coolant, transmission fluid, and power steering fluid. Certain embodiments of the present disclosure effectively hold and transfer a fluid or a fluid substance, further being able to open, close, and regulate fluid flow. Embodiments include a single piece tubular component that includes a cap interiorly attached to such tubular component with ribs, and a container having a tapered end. In certain embodiments, a nozzle having a tapered end is adapted to attach to a container.
US09981784B2 Manway cover
A manway cover assembly can be used to control access to the interior of a railroad tank car or other type of tank or structure. The manway cover assembly can have a tightening system, such as a screw tightening system and an attachment system. The attachment system can have a ledge configured to engage a flange that surrounds an opening. A cover can control access to the opening. The tightening system can secure the ledge to the flange and lock the cover over the opening. A manway cover assembly can also be used for selectively sealing an access passageway of a tank. The manway cover assembly can have an internal seal that remains sealed independent of movement between the cover and the opening within a set range of movement.
US09981783B2 Metal container with slideable top
A metal container having a metal and a metal bottom that slide relative to one another along a sliding axis is provided. The metal container includes a plastic lid insert attached to the metal lid and a plastic bottom insert attached to the metal bottom that operably couple the metal lid to the metal bottom and provide the structures allowing for a relative sliding motion between the metal lid and the metal bottom.
US09981779B2 Rope fixture, bag opening binding tool, and flexible container bag
A rope fixture 11 fixes a closing rope 12 for binding a bag opening of a flexible container bag 20A as a bag body, and includes a plate-shaped body in which a through-hole and a slit are formed, wherein a through-hole 13 allows the closing rope 12 to pass therethrough and a slit 14 nips and locks the closing rope 12 and has an insertion opening 17 provided at one end located at a lateral side of the plate-shaped body 15 and has a rope locking portion 18 allowing the closing rope 12 to pass therethrough and locks the closing rope 12 provided at the other end.
US09981778B2 Container for transporting goods and device for dividing such a container
A container includes a bottom, lateral walls, and a device for dividing the interior of the container. The device has a groove at each opposing lateral wall and a partition. Each groove extends from an upper edge of the lateral wall over a part of the height of the lateral wall. Each groove and the end faces of the partition have a cross-sectional shape transverse to their longitudinal extension, so that the end face of the partition and each groove can be united by a form-fit. Each groove can have an undercut.
US09981777B1 Beverage accessory hanger
Packaging for displaying an accessory with a beverage such as a wine bottle includes a compartment having a front, a tab coupled to the compartment for receiving and hanging from the neck of the wine bottle, and a window in the front of the compartment for displaying the accessory within the compartment.
US09981776B2 Food and beverage containers and methods of coating
Food and beverage containers and methods of coating are provided. The food and beverage containers include a metal substrate that is at least partially coated with a coating composition that includes a water-dispersible resin system and an aqueous carrier. The resin system includes an epoxy component and an acrylic component. In a preferred embodiment, the coating composition is at least minimally retortable when cured.
US09981775B2 Adjustable base device, system and method of use
An adjustable base container including a first surrounding wall forming a hollow internal space therein, the first surrounding wall having an inner surface including threads lengthwise and a male pattern design on a top portion of the inner surface, a second surrounding wall fitting within the first surrounding wall having one or more slit openings along its length extending completely through a bottom end in an axial direction, and having a female pattern design on a bottom side of a top end, the female pattern design corresponding to and fitting over the male pattern design of the first surrounding wall, and a platform sitting within the second surrounding wall having a top and bottom surface, a central space, and protrusions extending laterally from a rim edge, the protrusions engaging with the inner surface of the first surrounding wall between the threads. A method of using the adjustable base container.
US09981771B2 Integrated platform and folding carton tray
An integrated carton and liner assembly for consumer products includes a paperboard tray and thermoformed plastic insert. The sidewalls of the assembled carton are four layers thick, interleaved, and secured with snap fitments for exceptional sturdiness. The assembly is easy to assemble without adhesive, and achieves an upscale look. The thermoform liner is held securely in the carton.
US09981770B2 Packaging with a retractable handle and methods of making the same
Packaging for a product including a retractable handle. The retractable handle may be a foldable retractable handle configured to fold and unfold between a retracted position and an erect position. In the retracted position, retractable handle may be disposed with a body of the packaging. In the erect position, the retractable handle may extend from the body of the packaging. In some embodiments, the retractable handle may be composed of a paper-based material. In some embodiments, the retractable handle may be a single integrally formed piece of material.
US09981766B2 Method of applying labels using a portable labeling device
A portable labeling device is provided for applying labels to a film used in sealing a product package. The labeling device includes a platform mounted for adjustable positioning in relation to the film and a belt that is moveable around rollers associated with the platform. The belt is operable to receive a portion of each of the labels and transport them into registry with the film. A tamp roller is also provided and is moveable into a position pressing another portion of each of the labels against the film. The tamp roller is then movable to another position spaced away from the film when the belt moves around the rollers to transport other ones of the labels into registry with the film.
US09981765B2 Device and method for labeling individual packages
The invention relates to a device for labeling individual packages including a feed device for transporting a respective package in a transport direction, a printing device for printing a label, which can be removed from a material strip, wherein the printing device has a label dispensing unit for dispensing the printed label in a dispensing direction, and an application device for applying the printed label to the respective package. The application device has a manipulator for moving the printed label from a pick-up position, in which the printed label can be transferred from the label dispensing unit to the manipulator in the dispensing direction, to a dispensing position, in which the manipulator can apply the printed label to the package, via at least one transport position. The invention also pertains to a corresponding method for labelling individual packages.
US09981764B2 Easy to remove bag holder
A foldable stand includes four panels attached flexibly at lateral edges such that the panels can be folded in a closed configuration flat upon each other or folded into an open configuration to form a self-supporting free-standing stand.
US09981761B2 Machine and method of manufacturing a two-compartment pouch
A machine and a method for forming a two-compartment pouch having a lower compartment and an upper compartment The method includes the steps of drawing a film over a pair of fill tubes; sealing side edges of the film to form a sleeve; forming a bottom seal on the sleeve; pulling the sleeve downwardly; filling a bottom portion of the pouch using one of the fill tubes; forming a second seal over the filled bottom portion; filling an upper portion of the pouch using the other fill tube; and sealing the upper portion.
US09981759B2 Flexible containers and methods of making the same
A method of filling a product volume of a flexible container that includes a product volume and a structural support volume that at least partially extends into the product volume can include filling the product volume with product and applying an external force to the product volume and sealing the product volume to reduce a product receiving volume of the product volume.
US09981756B2 Total air temperature sensors
A total air temperature sensor includes a probe head, a strut, and a turbulence inducing surface. The probe head has an airflow inlet and an airflow outlet. The strut defines a leading edge and an opposed trailing edge extending along a longitudinal axis, and connects between the probe head and an opposed probe mount. The turbulence inducing surface is defined in the strut aft the leading edge. The turbulence inducing surface is configured to trip a fluid boundary layer passing over the strut to transition from laminar to turbulent for moving flow separation toward the trailing edge to reduce acoustic noise emission from the total air temperature sensor.
US09981754B2 System and method for detecting bad runway conditions
Systems and methods for detecting runway conditions are disclosed. A weight on wheel system may determine that an aircraft is on the ground. Wheel speed sensors may measure the speed of the aircraft wheels. Axle reference speeds may be calculated for each landing gear based on the speed of the aircraft wheels. A weight on wheel time limit may be reached prior to the axle reference speeds reaching an on ground threshold. A brake control unit may determine that the runway is contaminated if the on ground threshold was not reached.
US09981751B2 Casing for a propulsion unit
An aircraft propulsion unit comprising an engine and a nacelle including an axisymmetric casing (16) delimiting an air flow path, wherein this casing has at least two openings closed by removable and interchangeable panels (18), at least one of these panels carrying one component (24) of the propulsion unit.
US09981746B2 Dispensing architecture for a hybrid fountain beverage consumable cart and galley dispensing system
Embodiments of the invention described herein thus provide systems and methods for providing fountain beverage consumables in an easily accessible and removable and replaceable form. In one example, the fountain beverage consumables are provided on a cart that has interface connections with a dispensing unit. The dispensing unit may be mounted in a galley. When the cart is in its docking station with respect to the dispensing unit, fluid communication between the fountain beverage consumables and the dispensing unit is provided.
US09981745B2 Unmanned aerial vehicle including a removable parcel carrier
Systems and methods include UAVs that serve to assist carrier personnel by reducing the physical demands of the transportation and delivery process. A UAV generally includes a UAV chassis including an upper portion, a plurality of propulsion members configured to provide lift to the UAV chassis, and a parcel carrier configured for being selectively coupled to and removed from the UAV chassis. UAV support mechanisms are utilized to load and unload parcel carriers to the UAV chassis, and the UAV lands on and takes off from the UAV support mechanism to deliver parcels to a serviceable point. The UAV includes computing entities that interface with different systems and computing entities to send and receive various types of information.
US09981744B2 Drone
There is disclosed a drone including a main body comprising a motor, a shaft inserted in the main body vertically, a wing unit rotatable on the shaft by a power generated from the motor, the wing unit comprising a propeller unfolded horizontally and folded vertically, wherein the motor comprises a first motor and a second motor, and the shaft comprises an upper shaft inserted in the main body from a top vertically and a lower shaft inserted in the main body from a bottom vertically, and the wing unit comprises a first wing unit rotated on the upper shaft in a first direction by a power generated from the first motor, and a second wing unit rotated on the lower shaft in a second direction, which is the reverse of the first direction, by a power generated from the second motor.
US09981741B2 Unmanned aerial vehicle
Systems and methods are described herein related to an unmanned aerial vehicle, the unmanned aerial vehicle includes: a frame portion, two rear arms extending away from the frame portion, and at least one rear air propulsion device arranged on each of the rear arms at an orthogonal angle relative to a vertical axis. The at least one rear air propulsion device has an axis of rotation for both lift and rotation based on the angle. The unmanned aerial vehicle has two front arms arranged along a horizontal axis. The vertical axis is perpendicular to the horizontal axis. The unmanned aerial vehicle also includes at least one camera arranged on at least one of the front arms. The at least one camera faces a front direction.
US09981739B2 Anti-erosion structure for aircrafts
A structure (10) for aircrafts, includes a part (20) including a metal leading edge (30), the leading edge (30) being covered by a coating (40) having a thickness which is less than or equal to ten micrometers and having a hardness higher than six hundred in the Vickers hardness test (HV). According to a mode of embodiment, the coating (40) is a multilayer stainless steel coating consisting of a superposition of layers with a low nitrogen gradient and layers with a high nitrogen gradient, the layers having a thickness essentially equal to a micrometer. An aircraft including such a structure is also described.
US09981737B2 Method of fastening an aircraft wheel drive member on an undercarriage carrying a wheel
The invention provides a method of mounting an aircraft wheel drive member (30) on an undercarriage having an axle (1) that carries the wheel and that is provided with a torque plate (3) having an outside face against which a brake can be fitted, the method comprising the steps of fitting a support (10) that bears against an inside face of the torque plate opposite from its outside face against which a brake (2) is fitted, and of fitting the drive member on the support.
US09981736B2 Folding proprotor blade assembly having integral tang assembly
A tiltrotor aircraft includes a fuselage, a wing member extending from the fuselage, an engine disposed relative to the wing member, a rotor hub assembly mechanically coupled to the engine and a plurality of proprotor blade assemblies rotatably mounted to the rotor hub assembly and operable for beamwise folding relative thereto. The proprotor blade assemblies each including a spar and a sheath extending spanwise along a leading edge of the spar. The spar has a root section, a main section and a tip section. The spar has a generally oval cross section at radial stations along the main section of the spar with the root section of the spar forming an integral tang assembly operable for coupling the spar to the rotor hub assembly.
US09981731B2 AMR system with fly-by mode
The disclosed inventions include and apparatus and method for providing a universal Automatic Meter Reading (AMR) system configured with fly-by functionality. Such system may be configured to work in a plurality of modes including a walk-bay, drive-by, fixed network, and fly-by mode without hardware modifications. The system is configured to automatically calibrate so that the water meter transmitter operates at a minimum transmitted signal power level. Additional features include automatic hardware self-healing features where the system continues to function after certain hardware failures occur.
US09981726B2 Reversing propulsion device for watercraft
A human propelled watercraft having a pair of flexible fins extending into the water each adapted to oscillate through an arcuate path in a generally transverse direction with respect to the central longitudinal dimension of said watercraft. Pedals are provided for applying input force whereby as input force is applied, the flexible fins can twist to form an angle of attack for providing forward thrust with respect to the longitudinal dimension of the watercraft while moving in both directions along the arcuate path. The user can pull a lever and cause the fins to rotate 180° and produce thrust in the reverse direction. The fins are able to pivot and swing aft to avoid damage if there is a collision with a submerged object. The fins are more efficient, durable, and adjustable. Simple plastic roller bearings have been adapted to reduce mechanical friction without the need for oil seals.
US09981724B2 Small boat emergency stop apparatus
In a small boat emergency stop apparatus having an operator's cockpit and a passenger seat installed spaced apart from the cockpit, there are provided with an operator transmitter wearable by the operator to transmit a radio-wave signal of a predetermined strength, a passenger transmitters wearable by the passenger to transmit a radio-wave signal of the same predetermined strength and a receiver installed at a location closer to the cockpit than the passenger seat to receives the radio-wave signals transmitted by the operator and passenger transmitters successively. It is identified which of the operator and the passenger is a wearer of the transmitter and is then discriminated whether strength of the radio-wave signal transmitted from the identified wearer is smaller than a predetermined value. When it is, it is discriminated that emergency occurred in the wearer and an emergency action of engine stopping or engine speed reducing is performed.
US09981720B2 Device for and method of transferring personnel, equipment and/or structural elements from a surface vessel to an offshore structure
The invention relates to a device for transferring personnel, equipment and/or structural elements from a surface vessel to an offshore structure, such as a wind turbine, or to another vessel comprising a foundation mounted or to be mounted on a surface vessel, an arm pivotally connected to the foundation and at least one gripper connected to the free end of the arm for coupling the arm to an offshore structure. A second arm is pivotally connected to the first arm.
US09981718B2 Device and method for protecting towed underwater objects from fishing lines
A protective device configured to protect a line-cutting device mounted on a cable towed by a surface vessel comprises a blade holder comprising a blade, the blade being formed in the blade holder and being retractable into a slot about a transverse spring pin, wherein the protective device comprises a weighted body of hydrodynamic overall shape delimiting a transverse opening for the passage of the cable and an interior cavity in which the blade is arranged in such a way as to cut any line caught in the cavity, the protective device free to rotate about the cable.
US09981717B2 Electronic shifting systems and methods
The invention provides a wireless control system for a bicycle, including at least one shift unit including a shift actuator, and a master control unit in communication with the shift actuator. The master control unit transmits on a channel and listens for noise on the channel. When the master control unit receives an input signal from the shift actuator, the master control unit transmits a plurality of shift signals corresponding to the input signal for a message duration time if the channel is free of noise.
US09981712B2 Shock absorber incorporating a floating piston
A shock absorber includes a first end and a second end that reciprocate relative to one another. The shock absorber includes a gas spring chamber, a damping chamber, and a floating piston. The first side of the floating piston is in fluid communication with the gas spring chamber. The second side of the floating piston is in fluid communication with the damping chamber. The gas in the gas spring chamber applies pressure against the floating piston, which applies pressure to the substantially incompressible fluid in the damping chamber. This pressure transfer may be adequate to minimize or prevent cavitation.
US09981711B2 Suspended spindle assembly for recumbent tricyles
A suspended spindle assembly is disclosed for each of the front wheels of recumbent tricycles which absorb vibration and bumps to reduce rider fatigue while improving trike handling and rider comfort.
US09981710B2 Suspension structure of saddle-ride type vehicle
A shock absorber has an inner tube embedded in a steering stem shaft and an outer tube provided slidably. A front fork is fixed to a lower end of the outer tube, and the inner tube is fixed to an upper end of the steering stem shaft. The steering stem shaft is provided with a guide trench extending in a telescoping direction and having a long hole shape. A roller bearing is provided on an outer circumferential surface of the outer tube and is inserted into the guide trench movably along the guide trench. As a result, relative movement between the steering stem shaft and the outer tube in the telescoping direction is permitted while relative rotation is restricted.
US09981706B2 Bicycle stand
A bicycle stand which includes a frame with a first channel support and a transversely extending second channel support which are configured to engage with parts of a rim of a bicycle wheel.
US09981704B2 Track changing apparatus and methods associated therewith
A track changing apparatus for changing a track on an armored vehicle includes a plurality of moveable elements. The plurality of moveable elements of the track changing apparatus allows a track to be manipulated from loose or unmounted state, to a tensioned state wherein the track is located on the track changing apparatus, and finally, to a fully mounted state wherein the track has been transferred onto the armored vehicle. In at least one embodiment, the track changing apparatus may be used to remove a track from an armored vehicle. Methods of using a track changing apparatus are also described, including a method of mounting a track onto an armored vehicle.
US09981703B2 Track system
A track system for use as a wheel replacement on a vehicle comprises a first drive wheel configured to be mounted to the vehicle, a first frame pivotally yet non-drivingly mounted to the first drive wheel, a second frame mounted to the first frame, at least a second drive wheel pivotally mounted to the second frame, at least an idler wheel pivotally mounted to the second frame at a second extremity, and at least an endless traction band disposed about the second drive wheel and the idler wheel. The second drive wheel is configured to drivingly engage the traction band. The first drive wheel is operatively coupled to the second drive wheel via a transmission mechanism (e.g. a loop) such that rotation of the first drive wheel causes the rotation of the second drive wheel.
US09981702B2 Motor vehicle structure having a holding element for holding a spare wheel or other component on a floor portion made of plastic material
A motor-vehicle structure includes an underbody portion of sheet-metal defining an aperture with within there is mounted a floor portion of plastic material or composite material, for housing a spare wheel or other component of a vehicle, such as an electric or electronic component and/or for example a unit for accumulating electric energy. To said floor portion of plastic material or composite material there is associated a holding element having at least a first part anchored to the underbody portion of sheet-metal and at least a second part which can be anchored to said spare wheel or said other component, so that in case of an accident, said holding element prevents said spare wheel or said other component from being projected far away from the underbody structure, by constraining it instead to remain within a distance corresponding to one dimension of said holding element.
US09981701B2 Vehicle understructure
A vehicle understructure includes a left undercover and a right undercover provided in an underpanel. The left undercover is provided from below inside in a vehicle width direction with respect to a left side sill between a left front wheel and a left rear wheel. The right undercover is provided from below inside in the vehicle width direction with respect to a right side sill between a right front wheel and a right rear wheel. Each of the left undercover and the right undercover includes a lowering portion. The lowering portion can lower from the underpanel during driving and extends in a vehicle longitudinal direction such that the vehicle longitudinal direction becomes a longitudinal direction.
US09981698B2 Vehicle tunnel floor structure
A tunnel structure in an electric vehicle for providing a protected battery storage location and for increasing the stiffness of a vehicle's body structure. The tunnel structure may include a floor portion coupled to the floor of the vehicle, a front portion coupled to the vehicle firewall, and a paneled portion extending between the front portion and the floor portion. The tunnel structure may also include a plurality of panels and ridges that extend from the front portion toward a rear edge of the floor portion. The specific arrangement of the panels and ridges can improve the transfer of energy in the event of a collision.
US09981695B2 Vehicle lower-body structure
A vehicle lower-body structure includes a front pillar, including a front-pillar outer panel and a front-pillar inner panel, and a side sill, including a side-sill outer panel and a side-sill inner panel and joined to a lower portion of the front pillar. The front-pillar outer panel is joined to an outer surface of the side-sill outer panel. The front-pillar inner panel is held between the side-sill outer panel and the side-sill inner panel. The side-sill outer panel and the side-sill inner panel respectively include vertical beads in front of a reinforcement member disposed at a front portion of the side sill and below the front pillar, the vertical beads extending vertically.
US09981688B2 Steering system and independent suspension wheel-type heavy vehicle
The present invention relates to a steering system and an independent suspension wheel-type heavy vehicle. The steering system comprises a steering mechanism for providing a steering force to wheels and a steering hydraulic assisting system for providing a steering assisting force overcoming a steering resistance moment from the ground to the wheels. According to the invention, by providing the steering mechanism for providing a steering force to wheels and by providing the steering hydraulic assisting system for providing a steering assisting force overcoming a steering resistance moment from the ground to the wheels, the steering resistance moment from the ground can be effectively overcome, and the vehicle is offered the steering capability for various places, as compared with a steering system only depending on the torque output by a steering gear or only depending on the torque output by the steering gear and a steering assisting follower.
US09981685B2 Steering control device
A steering control device can restrain a steering from being operated to cause a steered angle and a steering angle to exceed their upper limit values. A first limiting reaction force setting circuit increases a first reaction force rapidly if the steering angle becomes no smaller than a steering angle threshold. A second limiting reaction force setting circuit increases a second reaction force rapidly if the steered angle becomes no smaller than a steered angle threshold. A target steering angle setting circuit sets a target steering angle based on steering torque applied to the steering minus the first reaction force, the second reaction force, etc. A steering angle control circuit sets reaction torque as a manipulated variable for feedback controlling the steering angle to the target steering angle. An operation signal generation circuit outputs an operation signal to a reaction force motor so as to achieve reaction torque.
US09981684B2 Vehicle power steering control apparatus
A vehicle steering control apparatus includes a power-supply supply portion 101 supplying a power supply to a micro-controller 102, an inverter 104 supplying power to drive a motor 5, a gate driver 103 controlling the inverter 104, a motor relay 105 opening and closing a current-passing path between the inverter 104 and the motor 5, a motor relay driver 106 controlling the motor relay 105, and a monitoring control portion A 108a and a monitoring control portion B 108b monitoring a power-supply voltage of the power-supply supply portion 101. Because multiple monitoring control portions are included, even in the event of an inconvenience in either one of the monitoring control portions A 108a and B 108b, the motor 5 can be stopped quickly in a reliable manner when the power-supply voltage goes out of a normal operation range.
US09981682B2 Electric power steering apparatus
[Problem]An object of the present invention is to provide an electric power steering apparatus that performs a judgment of a manual input during an automatic steering control by an accurate and precise method based on the mechanical equation, and have a steering performance which a driver and a fellow passenger do not feel uncomfortable.[Means for solving the problem]The present invention is an electric power steering apparatus that assist-controls a steering system by driving a motor based on a motor current command value and has a function performing an automatic steering control and a manual steering control, comprising: a function that calculates a time series response of a torsion bar torque based on a mechanical equation due to characteristics of a handle and a torsion bar, judges an adaptation degree of the calculated steering torque calculated-value and a detected value of the torsion bar torque, and judges “presence” or “absence” of a manual input during the automatic steering control by means of the adaptation degree.
US09981680B2 Energy absorption member for a vehicle
A vehicle includes a vehicle support structure and a steering linkage. The vehicle support structure includes a dash wall. The dash wall separates an engine compartment and a passenger compartment. The dash wall has an energy absorption member supported by the support structure on an engine compartment side of the dash wall. The steering linkage extends through an opening of the dash wall between the engine compartment and the passenger compartment. The steering linkage includes a steering column in the passenger compartment. The steering linkage further includes an abutment. The abutment is positioned and configured to contact the energy absorption member upon a frontal impact of the vehicle to transfer energy from the steering linkage to the energy absorption member and to limit a rearward displacement of the steering linkage.
US09981676B2 Derail alarm systems
A derail alarm system for notifying a tamping machine operator that a tamping projector buggy is in a derailed condition. A rail sensor with an ultrasonic beam attaches to a tamping projector buggy to sense alignment with a metal rail. When the ultrasonic sensor detects an out-of-tolerance condition, aural and red-LED light visual indications are electronically provided to the tamping machine operator. The tamping machine operator may disable the aural indication and change the red-LED indication to an amber-LED indication until the ultrasonic sensor detects an in-tolerance condition. A limit switch deactivates the cradle sensor when the tamping projector buggy is raised and stored in the travel position for a higher speed transport condition.
US09981671B2 Railway inspection system
A railway inspection system for monitoring defects of a rail, including an inspection vehicle configured for traversing the rail, a sensor disposed on the vehicle configured for obtaining rail condition data, a memory disposed on the vehicle and storing previous rail condition data from a previous traversal of the rail, a display device disposed on the vehicle, a processor disposed on the vehicle and a non-transitory computer-readable medium disposed on the vehicle and containing instructions, which when executed by the processor, cause performance of the following steps in real-time as the vehicle traverses the rail, namely obtaining current rail condition data from the sensor, displaying on the display device representative images of the current rail condition data, retrieving the previous rail condition data from the memory, and displaying on the display device representative images of the previous rail condition data.
US09981670B2 Gangway arrangement, intended to equip a public transport jointed vehicle, in particular a railway vehicle
A gangway arrangement can be laid out between two bodies of a public transport jointed vehicle, such as a railway vehicle. The gangway arrangement includes at least one seat for at least one passenger. The gangway arrangement can be connected through a pivot connection to the end portion of one of the bodies. The end portion includes an access corridor delimited by two opposite edges. The seat has an end extending to one of the edges when the gangway arrangement is connected to the body. An angular spacing is provided between the end of the seat and the edge, when the longitudinal direction is aligned with the longitudinal axis of the corresponding body. This angular spacing is relative to the pivot connection, and corresponds to the angle formed between the longitudinal axis of the body and the longitudinal direction when the tilt between both bodies is maximum.
US09981669B2 Controlling driving modes of self-driving vehicles
A computer-implemented method, system, and/or computer program product controls a driving mode of a self-driving vehicle (SDV) when a driver receives a telecommunication message on a telecommunication device. An SDV on-board computer within the SDV detects that the SDV is currently being operated in manual mode by a human driver. The SDV on-board computer detects that a telecommunication device located within the SDV is receiving a telecommunication message. In response to detecting that the telecommunication device within the SDV is receiving the telecommunication message, the SDV on-board computer transfers control of the SDV to the SDV on-board computer in order to place the SDV in autonomous mode, where the SDV is in the autonomous mode when steering, braking, throttle control, and obstacle avoidance by the SDV are all controlled by the SDV on-board computer.
US09981668B2 Operator control device and method for actuating functional units of a motor vehicle
At least one operator control element which can be moved by an operator is included in an operator control device. Furthermore, the operator control device includes an actuator with which activation of the operator control element can be communicated to the operator. The actuator includes a coil element and an armature which can move relative to the coil element. The armature is secured to the operator control element. The operator control device also includes an evaluation device with which a position of the armature relative to the coil element can be detected.
US09981665B2 Energy storage and delivery for power trains of work vehicles
A power train arrangement for a work vehicle with an engine may include an infinitely variable power source (“IVP”). An energy storage device may be configured to receive energy from the IVP for storage and to provide stored energy from the energy storage device to power one or more components of the IVP. A transmission may be configured to relay power from the engine and from the one or more components of the IVP to other components of the vehicle. A transient power event may be identified, during which a present operating state of the engine does not provide sufficient power for operations of the work vehicle. The energy storage device may be caused to provide stored energy to power the one or more components of the IVP source and thereby to provide power to the transmission.
US09981659B2 Driving assist device
Provided is a driving assist device 10 that recognizes an object in the vicinity of a moving body, and assists a driver in driving the moving body, the apparatus including: an object detecting unit 12 that detects the object in the vicinity of the moving body; a three dimensional object detecting unit 13 that detects a three dimensional object in the vicinity of the moving body; and an object recognition unit 18 that recognizes the object at a predetermined detection position as a non-obstacle when the object information storing unit 16 stores the position of the object, and the three dimensional object information storing unit 17 does not store the position of the three dimensional object at the predetermined position in which detection is performed by both of the object detecting unit 12 and the three dimensional object detecting unit 13.
US09981658B2 Autonomous driving vehicle system
An autonomous driving vehicle system includes: a surrounding information detection unit that is configured to detect surrounding information on a vehicle; and at least one electronic control unit including: a travel plan generation unit configured to generate a travel plan along a pre-set target route based on the surrounding information and map information; a traveling control unit configured to autonomously control a traveling of the vehicle based on the travel plan; and a warning light control unit configured to turn on a warning light earlier than a start time of a braking of the vehicle in the travel plan, the warning light informing a following vehicle about the braking.
US09981646B2 Brake cylinder
A spring-type brake cylinder that includes a compression spring, a pressure chamber, a dividing wall disposed between the compression spring and the pressure chamber, a piston having an inner wall and a bottom, and a nut disposed inside the piston and configured to be held on a release bolt. A support structure is disposed inside the piston and configured to abut against the nut while the release bolt is screwed into the nut. The piston comprises a first retaining structure and a second retaining structure, the first retaining structure configured to hold the support structure in an assembly position and the second retaining structure configured to hold the support structure in a drive position. The support structure is moveable from the assembly position to the drive position by a movement of the nut relative to the piston.
US09981645B2 Electric brake system
An electric brake system is disclosed. The electric brake system comprises a hydraulic pressure supply device configured to generate hydraulic pressure using a hydraulic piston which is activated by means of an electrical signal that is output corresponding to a displacement of a brake pedal, and including a cylinder block, first and second hydraulic pistons movably accommodated inside the cylinder block, and first and second pressure chambers comparted by the first and second hydraulic pistons, a first hydraulic circuit configured to connect a first hydraulic flow path communicating with the first pressure chamber to one or more wheel cylinders, a second hydraulic circuit configured to connect a second hydraulic flow path communicating with the second pressure chamber to one or more wheel cylinders, and a balance valve configured to open and close a balance flow path connecting the first hydraulic flow path to the second hydraulic flow path.
US09981643B2 Method and system for an aspirator for a brake booster
Methods and systems are provided for providing vacuum to a brake booster via an aspirator system. In one example, a system may include an aspirator system fluidly coupled with a brake booster with no intervening components located therebetween.
US09981640B2 Method for ascertaining the offset value of a sensor signal
A method is described for ascertaining the offset value of a sensor signal in a vehicle after the end of a parking period, in which the vehicle was parked, including the steps ascertaining the offset value of the sensor signal prior to the start of the parking period, storing the ascertained offset value in a data memory, ascertaining the changed offset value of the sensor signal after the end of the parking period from the offset value ascertained prior to the start of the parking period and the sensor signal present after the end of the parking period.
US09981636B2 Wiper blade and method for manufacturing wiper blade
A wiper blade extends in a longitudinal direction and includes a blade rubber, a plate spring-like backing, and a rubber holder. The blade rubber wipes a wiped surface. The backing adds rigidity and elasticity to the blade rubber. The rubber holder holds an intermediate portion of the blade rubber in the longitudinal direction and an intermediate portion of the backing in the longitudinal direction. The rubber holder includes a backing accommodation slot that accommodates and holds the backing. The backing accommodation slot extends through the rubber holder in the longitudinal direction. The parting line is set in a middle section of the backing accommodation slot in the longitudinal direction.
US09981631B2 Methods and systems for starting a vehicle
Systems and methods for selectively activating operation of one or more vehicle powertrain elements are presented. In one example, a propulsion source of a vehicle is activated in response to a driver moving a shift lever from a first location to a second location. Further, activation of propulsion source may be made contingent on whether or not the vehicle is coupled to an electrical grid.
US09981629B2 Child restraint system for use in vehicles
Systems for retraining an occupant within a vehicle seat as disclosed herein include a lap belt having connectable lap-belt segments along a seat bottom extending from respective connection points with the seat or the vehicle. A connection element extends upwardly along a seat back from an attachment point to a connecting member, and shoulder straps extend from the connecting member for placement over the occupant's shoulders when seated within the vehicle seat. The lap-belt segments may be connected directly or indirectly with the shoulder straps, and shoulder strap length may be adjusted via the lap-belt segments or an intermediate element used to connect the lap-belt segments with the shoulder straps. A vertical belt extends from the connecting member along the back portion of the vehicle seat to an attachment point within the vehicle.
US09981626B2 Vehicle body equipped with airbag system
A vehicle body 10 equipped with an airbag system has a side curtain airbag 20 provided on a roof side rail 12. The side curtain airbag 20 includes: a bag body 51 that is disposed along the roof side rail 12; a central protector 59 that holds the bag body 51; and an inflator 52 that is configured to feed gas to the bag body 51. The central protector 59 has a contact end part 65 that is opposed to a reinforcement member 48 with a gap L2 left therebetween. The contact end part 65 is moved toward the reinforcement member 48 by a deployment force of the bag body 51, and the contact end part 65 is thus supported by the reinforcement member 48.
US09981624B2 Seat assembly with air bag
A seat assembly for a motor vehicle includes: a supporting structure, designed to be mounted on the floor panel of the motor vehicle; a seat, which is mounted on the supporting structure and includes a sitting portion and a backrest portion; and an airbag unit, including at least one airbag, which is folded into a housing provided in the seat assembly and is inflatable into an expanded condition outside the housing, whereby the at least one airbag has a conformation such that, in the expanded condition, the at least one airbag identifies a protection wall that surrounds the backrest portion of the seat.
US09981623B2 Occupant restraint system for vehicle
An occupant restraint system 1 includes a seatbelt device 3 having a webbing 5 that is designed to extend obliquely across an occupant, seated on a seat, so as to pass through a shoulder part located on one side in a lateral direction and a part in front of a waist part located on the other side, and thereby to restrain an upper body of the occupant. The occupant restraint system 1 also includes an airbag device 4 having a bag body 10 that is installed on the webbing 5 in a folded state and designed to expand and deploy upon input of an impact load and thereby to restrain a periphery of a neck part of the occupant.
US09981617B1 Engine sound enhancement systems and methods using predicted values
An engine control module (ECM): based on an accelerator pedal position measured using an accelerator pedal position sensor, determines at least one of a predicted engine speed and a predicted torque output of an engine; and transmits the at least one of the predicted engine speed and the predicted engine to a network bus. An audio control module: is separate from the ECM; obtains the at least one of the predicted engine speed and the predicted torque output from the network bus; based on the at least one of the predicted engine speed and the predicted torque output, sets at least one of a frequency at which to output a predetermined engine sound and a magnitude for outputting the predetermined engine sound at the frequency; and applies power to at least one speaker of the vehicle to output the predetermined engine sound at the frequency and the magnitude.
US09981614B2 Fastener clip
A fastener is provided for mounting a first structure having an insertion rib with a retention slot to a second structure having a mounting opening. The fastener includes a U-shaped body having a bight portion at an upper portion thereof with a pair of outer legs depending therefrom. Each of the pair of outer legs terminates at a distal free end to engage an edge of the mounting opening when the U-shaped body penetrates the mounting opening. A pair of inner legs extends from the distal free ends of the outer legs toward the bight portion. The pair of inner legs has an intermediate protrusion configured to engage the insertion rib and bear against a stop in the retention slot to retain the U-shaped body on the first structure.
US09981613B2 Headrest and vehicle seat with integrated speakers
To prevent a person from experiencing discomfort when touching portions of a headrest having built-in speakers; to enable the headrest to be formed compactly by arranging the speakers close to the body of the person; and to prevent any decrease in the acoustic pressure and/or acoustic quality of sound from the speakers. Provided are: a plurality of speakers 25a, 25b; fiber pads 15 provided to the front surfaces of the speakers 25a, 25b; a sound-insulating pad 16 provided between the fiber pads 15; and a surface skin 9 for covering the speakers 25a, 25b, the fiber pads 15, and the sound-insulating pad 16, the fiber pads 15 being formed from an elastic material that has a three-dimensional-mesh structure therein, and the sound-insulating pad 16 being formed from an elastic material for minimizing the transmission of sound.
US09981609B2 Rotating luggage bin
An apparatus comprising a structure having a cavity with an opening configured to receive a piece of baggage and a flange configured to retain the piece of baggage when the structure is in an open state, wherein the structure is configured to move between the open state and a closed state about an axis of rotation for the structure, and wherein the opening has a horizontal position when the structure is in the closed state and the opening has a vertical position when the structure is in the open state.
US09981600B2 Adjustable truck cover light
A pickup truck is provided that includes a tonneau cover or bed cap that includes a lighting system. The light system is selectively attached to the tonneau cover or bed cap. The light system includes a longitudinally extending rod having an illuminating portion extending along at least a portion of the longitudinal extent of the rod. The longitudinally extending rod includes first and second end portions and an on/off switch located at least adjacent to the first end portion of the longitudinally extending rod. At least one clip is attached to the tonneau cover or bed cap that selectively holds the longitudinally extending rod. The longitudinally extending rod is pivotable within the at least one clip such that the illuminating portion is selectively directable toward different directions.
US09981599B2 System and method for activation of warning lights of a vehicle
There is provided a method for activating warning lights in a vehicle, the method comprising: determining a yaw rate of the vehicle; determining a sideslip angle of the vehicle; comparing the yaw rate to a predetermined yaw rate threshold value; comparing the sideslip angle to a predetermined sideslip angle threshold value; and f the yaw rate exceeds the predetermined yaw rate value; if the sideslip angle exceeds the predetermined sideslip angle value; and if it is determined that the vehicle reaches a standstill within a predetermined time after the yaw rate and sideslip values have been exceeded, activating warning lights of the vehicle. There is also provided a system configured to perform the above described method.
US09981595B2 Vehicle lamp
Provided is a vehicle lamp including an optical unit including an optical element and a solenoid that drives the optical element; and a driving circuit configured to receive a voltage from a DC power supply and apply a driving voltage to the solenoid. The driving circuit includes a signal generating circuit that generates a notification signal indicating whether or not the solenoid is open-circuited. The signal generating circuit generates a first signal as the notification signal when the solenoid is normal. The notification signal is set as a second signal that is different from the first signal when open-circuit of the solenoid is detected.
US09981594B2 Camera based headlight control system
A lighting system for a vehicle is disclosed. The lighting system comprises an imager configured to capture image data in a plurality of image frames in a rearward field of view. The system further comprises at least one headlamp configured to output an emission of light at a plurality of elevations and a controller. The controller is in communication with the imager and the headlamp. The controller is operable to process the image data to identify features in a first frame and a second frame. The controller is further operable to identify a movement of the features from the first frame to the second frame and adjust the elevation of the output emission in response to the movement.
US09981592B2 Lighting structure
A lighting structure includes a light source; a first lens; and a second lens. The second lens is located between the light source and the first lens. An angle between an optical axis of the first lens and an optical axis of the second lens is not more than 90 degrees. The light emitted from the light source which is not taken and refracted by the first lens is taken and refracted by the second lens.
US09981591B2 System for lifting and launching a boat
A device for launching and lifting a boat has a frame that includes at least a first frame part having a first end and a second end, at least a first cross-structure coupled with the first frame part essentially perpendicular to it and at a distance B1 from the first end of the first frame part, at least a first boat guide arranged on the first frame part at a distance C1 from the first end of the first frame part; and at least a first actuator arranged to be coupled with the first frame part at a distance D from the first end of the first frame part, at least one counterpart, and means for attaching the frame to the counterpart, wherein the first actuator is arranged to be coupled with the counterpart for enabling movement of the frame between a first position and a second position.
US09981586B2 Headrest and vehicle seat having headrest
A vehicle seat includes a seat back, and a headrest that is provided above the seat back. The headrest includes a pair of stays that form a part of a skeleton of the headrest, a pair of panel members that sandwich parts of the pair of stays from front and rear or above and below so as to connect the stays with each other, and are joined to each other through outer peripheries so as to form a space inside and form a part of the skeleton of the headrest, a cushion material that covers the pair of panel members and the parts of the pair of stays, and a dynamic damper arranged inside the space.
US09981581B2 Vehicle seat
A vehicle seat includes: a cover member that covers an ISOFIX anchor for fixing a child seat; an intermediate portion that is exposed at a position between the cover member and the ISOFIX anchor in a state where the cover member is opened; and a stopper that retains the cover member in a state where the cover member is opened, wherein the stopper has an engagement part and an abutting part, wherein the engagement part of the stopper is detachably engaged with at least one of the rear surface and the intermediate portion in a state where the cover member is opened, and wherein the abutting part of the stopper abuts on the other of the rear surface and the intermediate portion so as to prevent the cover member from being moved in a closing direction.
US09981574B2 Energy absorbing seat mechanism
A system includes a shear member and an energy absorber. The shear member is configured to couple a seat portion to a base structure of a vehicle. The shear member is configured to sustain a first load without fracture and configured to inelastically deform under a second load. The second load is greater than the first load. The energy absorber is coupled to the seat portion and coupled to the base structure. The energy absorber is configured to absorb the energy following deformation of the shear member.
US09981562B2 Power supply system
A power supply system includes: a first battery; a second battery; a voltage converter including a plurality of switching elements; and a controller configured to turn on or off the plurality of switching elements in accordance with pulse width modulation control. The controller is configured to control phases of the pulse width modulation control signals such that the first high-level period of the first pulse width modulation control signal and the second high-level period of the second pulse width modulation control signal do not overlap with each other at a predetermined condition.
US09981561B2 Overvoltage protection for a motor vehicle electrical system in the event of a load dump
A motor vehicle electrical system which includes an electric machine, an active bridge rectifier, and at least one control device, the at least one control device being configured for converting an alternating voltage which is output by the electric machine at a number of phase connections into a direct voltage by controlling active switching elements of the bridge rectifier. An arrangement is provided configured for initiating a short circuit of at least two of the phase connections as soon as a signal characterizing the direct voltage exceeds an upper threshold value, and for deactivating the short circuit as soon as the signal characterizing the direct voltage subsequently falls below a lower threshold value. An evaluation device is provided configured for detecting a value of the direct voltage, for filtering the detected value, and for providing the filtered value as the signal characterizing the direct voltage.
US09981555B2 State of charge indicator of hybrid vehicle
A state of charge indicator includes a first indication unit that provides an indication of a state of charge of a battery of a hybrid vehicle. The first indication unit includes a movable index and a fixed index. The movable index is movable in accordance with an increase and a decrease in the state of charge. The fixed index is disposed along a movement range of the movable index. The movable index is movable between positions corresponding to a maximum and a minimum of a state of charge range directed to an EV traveling mode and an HV traveling mode. The fixed index includes: a first sign that indicates switching from the EV traveling mode to the HV traveling mode; and a second sign that indicates switching from the HV traveling mode to the EV traveling mode.
US09981552B2 Clutch control device for four-wheel drive vehicle
A clutch control device is provided for a four-wheel drive vehicle for transmitting drive force to the rear wheels. The clutch control device includes a dog clutch and a friction clutch, and a 4WD control unit that controls the engagement and disengagement of the dog clutch and the friction clutch. The 4WD control unit is switchable between a two-wheel drive mode and a four-wheel drive mode. The 4WD control unit is programmed to control engagement of the dog clutch so that the dog clutch is engaged after the friction clutch is engaged and the dog clutch is synchronized. During engagement of the dog clutch, the 4WD control unit is programmed to reduce a transmission torque of the friction clutch when the dog clutch engagement standby state is detected.
US09981550B2 Vehicle body mounting structure for a fuel tank
To provide a vehicle body mounting structure for a fuel tank tank, which can suppress deformation of the fuel tank due to a band member while suppressing increase in weight of the fuel tank, the vehicle body mounting structure for a fuel tank includes: a band member (21) disposed along a lower surface (14) of the fuel tank (1) made of resin and having both ends secured to the vehicle body; an upper groove (31) formed in a side surface (12) of the fuel tank (1) to extend downward from an upper surface (13) of the fuel tank (1) over at least a part of the side surface (12) of the fuel tank (1); and a cushion member (26) interposed between the fuel tank (1) and the vehicle body and straddling the upper groove (31).
US09981549B2 Splash resistant oil tank fill tube
A fill tube for an oil tank may have at least one baffle coupled to an inner wall of the fill tube. A first baffle may have an aperture. A release tube may be coupled to the baffle at the aperture. An object may be inserted through the aperture. The object may force open a flapper valve coupled to the fill tube. Pressure in the oil tank may be released through the flapper valve. The baffles may prevent hot oil from spraying out of the fill tube. After the pressure has been equalized, oil may be poured into the fill tube to fill the oil tank.
US09981548B2 Filler neck housing or charging housing
A filler neck housing or charging housing for insertion into a body opening in a motor vehicle, comprising a housing section with a first sealing section and a second sealing section, the first sealing section being provided on an outer edge, which can be inserted into the body opening, of the housing section and being designed to bear in a sealing manner on the body opening, and the second sealing section being provided on a passage opening in the housing section, into which a tank filler pipe or a plug-in charging connector can be inserted, the second sealing section being designed to bear in a sealing manner against the tank filler pipe or the plug-in charging connector.
US09981546B2 Valve device for fuel tank
A fuel tank valve device includes a housing in which a partition wall defines a lower valve chamber and an upper ventilation chamber, and a first opening and a second opening are provided to establish a communication between the lower valve chamber and the upper ventilation chamber, a first float valve that is accommodated in a first valve chamber of the lower valve chamber so as to rise and fall and that closes the first opening when a fuel level in a fuel tank nearly reaches a set full fuel level, and a second float valve that is accommodated in a second valve chamber of the lower valve chamber so as to rise and fall and that closes the second opening when the fuel level in the fuel tank rises abnormally.
US09981542B2 Vehicle control device
Appropriate vehicle stability control is enabled in a vehicle configured to carry out regeneration enhancement control. A predictive deceleration support control unit is configured to set a position at which the vehicle is predicted to finish deceleration as a target deceleration end position, and guide a driver to release an accelerator pedal so that the deceleration of the vehicle is finished at the target deceleration end position, to thereby carry out regeneration enhancement control under a state in which the accelerator pedal is released so as to generate a larger deceleration than in a normal state. The predictive deceleration support control unit is configured to read a vehicle stability control flag from a brake ECU and stop the regeneration enhancement control when the vehicle stability control is being carried out.
US09981541B2 Protection structure of battery module mounted in rear of vehicle body
A battery module is mounted in the rear of a vehicle body and attached to at least one rear side frame extending rearward in the vehicle body such that the rear side module protrudes rearward beyond the battery module. One or a plurality of slope members is provided at the rear of the battery module. Each of the slope members forms a frontward rising inclined surface that protrudes above the rear side frame at the rear of the battery module.
US09981540B2 Shielding device
A shielding device has a body, at least one slewing mechanism and two vehicle-top suction attachment assemblies. The body has a housing, a first cover and a second cover. The first cover and the second cover are mounted in the housing. The slewing mechanism has a spindle, a rotor, a rolling pipe, a rotating casing and a covering cloth. The spindle is mounted in the second cover. The rotor is mounted on and around the spindle and has a fastening portion, a torsion spring and a securing ring. The torsion spring is connected to the fastening portion. The securing ring is securely mounted on and around the spindle. The fastening portion is fastened in the rolling pipe. The rotating casing is mounted pivotally in the first cover. The covering cloth is mounted on the rolling pipe. The vehicle-top suction attachment assemblies are mounted on the body.
US09981539B1 Open roof construction for a vehicle
An open roof construction for a vehicle having a roof opening in a fixed roof having a roof edge, defining the roof opening and protruding in a downward direction and further comprising a stationary part, at least one panel to open and close the roof opening. The panel is movably supported by an operating mechanism, guided in a guide rail of the stationary part, extending along at least a longitudinal side of the roof opening. The panel is movable in vertical and longitudinal directions with respect to the roof opening. The stationary part is provided with a sealing assembly comprising a first seal part capable of sealing the panel towards the fixed roof, and a second seal part capable of sealing the stationary part against an inner part of the fixed roof. The first seal part is slidably adjustable with respect to the second seal part in vertical direction.
US09981534B2 Closed section geometry, hollow shape, vehicle components
In an embodiment, a vehicle component for a vehicle can comprise: a carrier comprising a top portion, a bottom portion, a first side portion, and a second side portion; a cavity, wherein the cavity comprises a bottom cavity wall, cavity side walls, and a top portion of the cavity having an upper cavity wall; an insert covering at least a portion of the cavity and attached to the upper cavity wall, the bottom cavity wall, and/or the cavity side walls; and a cover attached to the carrier.
US09981531B2 Drive device and method for operating a drive device
A drive device comprising at least one control unit (10) for operating a first drive unit (16) with a first operating frequency (fb1) from a first operating frequency interval and a second drive unit (18) with a second operating frequency (fb2) from a second operating frequency interval, which at least partly overlaps the first operating frequency interval. The control unit (10), in at least one operating state, operates the drive units at least occasionally simultaneously with different operating frequencies (fb1, fb2) and varies the first operating frequency (fb1) and/or the second operating frequency (fb2) within the respective operating frequency interval.
US09981527B2 Vehicle heater
A vehicle heater includes a plurality of heating units (12, 14) as well as a heat exchanger device (32) for transmitting heat provided in the heating units (12, 14) to a heat carrier medium (M). The heat exchanger device (32) includes, associated with each heating unit (12, 14), a heat exchanger zone for transmitting heat provided in the heating unit (12, 14) to the heat carrier medium (M).
US09981518B1 Apparatus and method of controlling amphibious vehicle
An apparatus for controlling an amphibious vehicle includes an engine, a land propeller generating a propulsion force on land, a water propeller generating a propulsion force on water, a power distributor distributing power to the land propeller and the water propeller, a transmission for changing a shift ratio of the power supplied to the land propeller, and a controller, wherein the controller selects and executes one of a land mode for controlling travel on land, a water mode for controlling travel on the water, and a transition mode controlling the travel in a transition region, and the controller maintains an engine output torque in the land mode to be constant and maintains an engine output speed in the water mode and the transition mode to be constant.
US09981517B2 Railway traction vehicle
Railway traction vehicle (1) that is equipped with four rubber wheels (6) and with four steel rail wheels (7), and all eight (8×8) can exert traction simultaneously on the rails over which a train is hauled. Each of the eight wheels is equipped with an individual hydraulic or electric motor (5) that can be controlled individually. The traction vehicle is equipped with tilting bogies (8a, 8b) with which the steel rail wheels can be raised or lowered. The tilting bogies also enable ballast bodies (24a, 24b) to be detached and placed on supports, by lowering the level of the supporting frame (2).
US09981516B1 Automatic ejecting and retracting trailer hitch
One embodiment of a trailer frame (9), which has a receiver section (4) made of a square metal tube on which the hitch (7) travels in and out as a result of the mechanical energy source activated at the push of a button located on the vehicle's dashboard, a button located in the trunk at the rear of the vehicle or by the remote access device. When extending the hitch is desired, the corresponding button is pressed activating the solenoid (5), subsequently activating the motor (1) and as a result the hitch extends for use. Immediately after the solenoid activates again, locking the hitch (7) to the receiver section of the trailer frame, thus transferring the load of the trailer from the motor and lead screw (3) to the trailer frame (9). When retracting is desired, the corresponding button is pressed activating the solenoid (5), subsequently activating the motor (1), as a result the hitch retracts for storage. After the hitch completes its travel, again the solenoid locks the hitch in place. Status indicators in the dash or trunk can inform the user of the position of the hitch (7) at all times. Other variations of this embodiment are possible.
US09981513B2 Anti-rattle device with hitch cover
An anti-rattle device is shown and described. The anti-rattle device may include a frame configured to engage a receiver hitch and to receive a draw bar. The anti-rattle device may also include a cam engaging assembly operatively engaged with the frame, where the cam engaging assembly is selectively positionable between disengaged and engaged positions whereby the cam engaging assembly is adapted to engage the draw bar against the receiver hitch in the engaged position.
US09981506B2 Combination of a heavy goods vehicle tire structure with a tread pattern
Tire for a heavy goods vehicle, comprising a crown reinforcement, and, radially outside this crown reinforcement, a tread having a total thickness PMU of material intended to become worn during running, the crown reinforcement being formed by at least two working plies and a protection ply positioned radially outside the working plies and radially inside the tread, the narrowest working ply having a width in the range from 70% to 90% of the width W of the tread, the protection ply having a width at most equal to 70% of the width of the narrowest working ply, the tread comprising grooves only in the part radially outside the protection ply, each circumferentially orientated groove having a depth at least equal to 75% of the maximum thickness intended to become worn PMU. This tread comprises, axially between an axial end of the narrowest working ply and an axial end of the protection ply located on the same side of the equatorial plane, a channel that is generally circumferentially orientated and runs all the way around the tire, this channel being formed in such a way that the minimum distances between this channel and the working plies and between this channel and the protection ply are different from zero.
US09981505B2 Tire with lamelle in bridge
A tire is provided having features in the tread elements that provide improved resistance to wear and, more particularly, irregular wear. More specifically, lamellae are provided along tread elements of the tire and between such tread elements to provide for improved wear patterns and particularly to provide resistance to irregular wear at the leading and trailing edges of the tread element.
US09981498B2 Sheet pasting and binding apparatus and sheet post-processing apparatus
A sheet pasting and binding apparatus has a paste application unit, an acquisition unit, a detection unit, and a controller. The paste application unit can change an application amount for applying paste to fed sheets. The acquisition unit acquires the number of printing instructed sheets. The detection unit detects the remaining amount of the paste. The controller controls the paste application unit so that pasting and binding are performed using a second paste application amount which is smaller than a first paste application amount while the pasting and binding are performed using the first paste application amount which is specified in advance as the paste application amount for maintaining a binding force between the sheets, based on the reception number and the remaining paste amount.
US09981497B2 Coated print medium
The present disclosure is drawn to a coated print medium, a method of preparing a print medium, and a printing system. The coated print medium can comprise a substrate and a coating applied to the substrate. The coating can comprise, by dry weight percent, 5 wt % to 30 wt % of a polymeric binder, 20 wt % to 50 wt % of a cationic latex, 5 wt % to 15 wt % of a multivalent cationic salt, and 1 wt % to 20 wt % of an optical brightener; and 5 wt % to 20 wt % of a cationic polyamine.
US09981495B2 Printer that performs shading correction and method for operating the same
A printer includes a discharge unit, a first printing unit disposed along a sheet conveying path extending from the discharge unit and configured to print an image on a first sheet while the first sheet is conveyed from the discharge unit to the first printing unit and then to the discharge unit, a second printing unit disposed farther from the discharge unit than the first printing unit along the sheet conveyance path and configured to print an image on a second sheet while the second sheet is conveyed towards the discharge unit therethrough, a scanning unit disposed along the sheet conveying path between the discharge unit and the first printing unit, and configured to scan a surface of the first sheet, and a control unit configured to perform a shading correction of the scanning unit using the second sheet as a white reference.
US09981494B2 Waste liquid container
A waste liquid container is mounted on a mounting portion including a discharging portion discharging waste liquid and an apparatus-side terminal portion in accordance with movement in a mounting direction. The waste liquid container includes a waste liquid containing chamber which is capable of containing the waste liquid, a connection opening which is opened in the mounting direction in a shape of being connectable to the discharging portion, and a container-side terminal portion which is electrically connected to the apparatus-side terminal portion at the time of being mounted on the mounting portion. In a state of being mounted on the mounting portion, the container-side terminal portion is disposed lower than the connection opening in a posture of being inclined with respect to the mounting direction.
US09981491B2 Tape cartridge
A tape cartridge detachably installed on a cartridge installation portion of a tape printing apparatus having a first shaft and a second shaft on the cartridge installation portion. The tape cartridge includes a tape accommodation area in which a printing tape and a tape core are accommodated. A platen has a first reception portion in which the first shaft is inserted when the tape cartridge is installed, and a second reception portion into which the second shaft is inserted when the tape cartridge is installed in the cartridge installation portion. When seen from an attaching direction of the tape cartridge, the tape cartridge has an appearance that is formed in an L-shape and of which a base end at a right side surface slightly projects. The first reception portion and the second reception portion are arranged each other from opposite side of the tape accommodation portion.
US09981489B2 Medium transport device, printing apparatus and liquid ejecting apparatus
A printer includes a transport unit that transports continuous paper (P), a medium support unit (20) in which a support surface (20a) that is capable of supporting continuous paper (P) that is transported by a transport unit, and first concave sections (24A and 24B), which are indented from the support surface (20a), are formed, and an image capture unit, which is disposed on a lower side of the support surface (20a), and which captures an image of a lower surface of the continuous paper (P).
US09981488B2 Modular vacuum belt assembly with interconnecting moving belt modules
A printer includes a modular vacuum belt assembly for moving print media in a media feed direction along a media path. The modular vacuum belt assembly includes a plurality of moving belt modules interconnected along a width of the media path. Neighboring moving belt modules are interconnected via a connecting fixed vacuum plenum.
US09981486B2 Ink jet recording method, ultraviolet curable ink, and ink jet recording apparatus
Provided is an ink jet recording method including: discharging first ultraviolet curable ink of a radical polymerization reaction type which contains a radical photopolymerization initiator and a radical polymerization compound and in which transmittance at a wavelength of 395 nm is equal to or less than 1%, onto a recording medium; and curing the first ultraviolet curable ink which is landed on the recording medium by irradiating the ink with ultraviolet light, in which a light source which initially emits the ultraviolet light in the curing of the ink is an ultraviolet light emitting diode in which peak intensity of the irradiated ultraviolet light is equal to or more than 800 mW/cm2.
US09981483B2 Printing apparatus
A printing apparatus includes a tray which supports a material for textile printing, and can move in a movement direction; a printing unit which performs printing on the material for textile printing supported by the tray; and a contact unit which is provided at a position of being in contact with the material for textile printing supported by the tray, before performing printing by the printing unit. By adopting the printing apparatus with such a configuration, it is possible to improve a printing condition when performing printing on the material for textile printing.
US09981480B2 Image recording method, ink, and liquid composition
An image recording method including the steps of applying an ink containing a coloring material and anionic resin particles to a recording medium, and applying a liquid composition to the recording medium so as to at least partly overlap with an area where the ink is applied, the liquid composition destabilizing a dispersion state of the coloring material or of the anionic resin particles in the ink. The ink contains a trihydric or higher polyhydric alcohol compound having a group formed by substituting a hydrogen atom of a hydroxyl group by a structure represented by —Rn—H, where R is an alkyleneoxy group including an ethyleneoxy group, and the number of Rs per molecule is 40 or more and 120 or less when the polyhydric alcohol is a trihydric alcohol and is 12 or more and 400 or less when the polyhydric alcohol is a tetrahydric or higher polyhydric alcohol.
US09981477B2 Liquid ejecting device and head
There are provided a liquid ejecting device that can efficiently supply liquid inside a liquid containing unit with a simple structure and the liquid containing unit. The present invention is the liquid ejecting device which includes a liquid container, a head that is provided on a carriage and has a liquid containing unit capable of storing liquid thereinside and a liquid ejecting unit, and a flexible member that connects the liquid container to the liquid containing unit and supplies the liquid stored inside the liquid container to the liquid containing unit. A holding member is arranged inside the liquid containing unit to hold the liquid, and the shortest distance between a supply port opened to an inside of the liquid containing unit and the holding member is 0.1 mm or more and 5.0 mm or less.
US09981476B2 Liquid discharge head
A liquid discharge head includes a recording element substrate including a recording element, an electronic substrate disposed outside the recording element substrate, an electric element mounted on the electronic substrate, a housing that supports the recording element substrate and the electronic substrate and is made of a first resin material, and a cover member that surrounds and shields the electric element and is made of a second resin material, wherein the second resin material has higher heat resistance than the first resin material.
US09981474B2 Liquid ejecting apparatus
A liquid ejecting apparatus includes a transport unit that transports a medium, an ejecting unit that ejects a liquid onto the medium in an ejection area, a mist-collecting unit that collects mist that occurs with the ejection of the liquid from the ejecting unit, and a contaminant-collecting unit that is formed upstream of the ejection area in a transport direction of the medium and that collects contaminants that have attached to the medium.
US09981472B2 Face-down printing apparatus and method
Film-forming apparatuses, systems, and methods are provided. The apparatus can include a substrate positioning system and a printing array that includes an inkjet printing array and/or a thermal printing array. The positioning system can be a gas-bearing plate system. The positioning system can be configured to move a substrate between a first position, away from the printing array, and a second position, above the printing array. The apparatuses, systems, and methods can be used to manufacture organic light emitting devices (OLEDs), for example, flat panel displays.
US09981471B2 Method for the surface treatment of a semiconductor substrate
The present disclosure relates to a method for the application of an antiwetting coating on at least one surface of a substrate of semiconductor material comprising the steps of: a) applying on said at least one surface a metal layer of a material chosen in the group constituted by noble metals, coining metals, their oxides and their alloys; and b) applying on said metal layer a layer of a thiol of formula R—SH, where R is a linear alkyl chain having from 3 to 20 carbon atoms and, optionally, at least one hetero-atom, for obtaining an antiwetting coating. The disclosure further regards a method for the production of a nozzle plate for ink-jet printing and to an integrated ink-jet printhead provided with a nozzle plate obtained according to the method of the disclosure.
US09981468B2 Ink jet printing apparatus and method for controlling inkjet printing apparatus
An ink jet printing apparatus is provided which can suppress defective ejection of ink from the nozzles. An element array with a plurality of print elements arranged therein is divided into a plurality of groups of print elements. For each of the plurality of groups, the apparatus determines whether any area undergoes a failure to perform a normal printing operation. If the apparatus determines, for any of the plurality of groups, that any area is likely to undergo the failure, when the print medium is printed based on the print data corresponding to the area, control is performed in such a manner that a first amount of energy supplied to drive one print element is greater than a second amount of energy supplied to drive one print element immediately before the print medium is printed based on the print data corresponding to the area.
US09981467B2 Categorization of vertical edges corresponding to a halftone image
A method of printing includes identifying vertical edges in a halftone image. The method also includes determining whether a lightness of color of a first predetermined area to a left side of a respective vertical edge is substantially equal to, less than, or greater than the lightness of color of a second predetermined area to a right side of the respective vertical edge. The method also includes categorizing respective vertical edges left vertical edges, right vertical edges, and neutral vertical edges to prioritize a print direction thereof.
US09981463B2 Method for manufacturing liquid discharging apparatus, liquid discharging apparatus, and device driver
A method for manufacturing a liquid discharging apparatus having a liquid discharging head that is attached to an apparatus main body so as to be capable of being attached or detached and that discharges a liquid from a nozzle includes: identifying an alignment shift of the liquid discharging head attached to the apparatus main body; and identifying correction information that is correlated with the alignment shift identified in the identifying of the alignment shift based on a correction information table in which the correction information related to liquid discharge control and the alignment shift are correlated with each other.
US09981461B1 Storage vessel for compressed fluids
A vessel for storing pressurized gas. The storage vessel may be manufactured in a variety of predetermined shapes. Plural frame members are interconnected with each other, collectively forming a lattice frame. A network of internal supports is disposed within the interior of the lattice frame, the internal supports being made of a carbon-reinforced composite material. The storage vessel has an outer shell made up of layers of carbon-reinforced composite material sheets enveloping the exterior of the lattice frame.
US09981457B2 Manufacturing apparatus of stack
The stack manufacturing apparatus includes a first supporting body supply unit which is configured to intermittently unroll a roll sheet-shaped first supporting body and includes one of a pair of tension applying devices capable of applying tension to the unrolled first supporting body; a first adhesive layer formation unit configured to form a first adhesive layer over the first supporting body while the first supporting body supply unit suspends unrolling of the first supporting body; a first bonding unit configured to bond the first supporting body and a sheet-shaped member using the first adhesive layer; and a control unit which is configured to hold an end portion of the first supporting body and includes the other of the pair of tension applying devices.
US09981454B2 Polyolefin pre-stretched packaging film
The invention provides a polyolefin pre-stretched packaging film comprising perforations arranged in a series of columns along a longitudinal direction of the film, wherein each adjacent column of said perforations is separated by a column without perforations along the longitudinal direction, and the perforations are staggered in a transverse direction across the film, wherein said film comprises an inherent cling surface on at least one of its surfaces; wherein the perforations cover at least 25% of the total surface area of the film, and the film has an inside/inside cling property of 5 to 22 gr, and a weight of no more than 13 g/m2.
US09981453B2 Photochromic polyurethane laminate
A photochromic polyurethane laminate that is constructed to solve certain manufacturing difficulties involved in the production of plastic photochromic lenses is disclosed. The photochromic laminate includes at least two layers of a resinous material and a photochromic polyurethane layer that is interspersed between the two resinous layers and which contains photochromic compounds. The polyurethane layer is formed by curing a mixture of a solid thermoplastic polyurethane, at least one isocyanate prepolymer, at least one photochromic compound, and a stabilizing system.
US09981451B2 Delamination resistant, weldable and formable light weight composites
The present invention relates to filled polymeric materials 16 including a thermoplastic polymer 18 and a metallic fiber 20 and to light weight composite materials 10, 12 which comprise a metallic layer 14 and a polymeric layer, the polymeric layer containing the filled polymeric material 16. The composite materials of the present invention may be formed using conventional stamping equipment at ambient temperatures. Composite materials of the present invention may also be capable of being welded to other metal materials using conventional welding techniques. The composites exhibit resistance to delamination.
US09981449B2 Stack of multi-panel sterilization assemblies
A continuous process for making a multi-panel sterilization assembly, the process including the steps of: providing a moving, continuous base web; providing a plurality of subassemblies; applying the subassemblies in position on the moving, continuous base web to define repeating portions that incorporate the subassemblies and alternating portions that lack such subassemblies; providing side tabs; applying the side tabs in position on the moving, continuous base web with respect to at least one edge of the portions that incorporate the subassemblies; attaching the subassemblies and the side tabs to the moving, continuous base web to form a continuous work-piece; and separating the continuous work-piece into individual multi-panel sterilization assemblies, each multi-panel sterilization assembly comprising a barrier panel, a fold protection panel and at least one side tab.
US09981448B2 Waterproof garment with invisible barrier seam
A waterproof invisible barrier seam is formed between two fabric laminates, an outer shell fabric laminate and an inner lining fabric laminate. The seam includes an invisible seam tape that forms a hydrostatic barrier within the seam. The design of the seam allows the formation of an effective hydrostatic barrier along the seams of a soft shell garment, while retaining flexibility, stretch, aesthetic appearance, and reversibility.
US09981446B2 Structural inserts for honeycomb structures
A method and apparatus for manufacturing a sandwich structure. A cavity is formed in a core of the sandwich structure. A structural insert is placed into the cavity. The structural insert comprises a first number of parts configured to receive a load and a second number of parts assembled with the first number of parts to form the structural insert.
US09981444B2 Reinforced stiffeners and method for making the same
A composite stiffener is fabricated using preforms of laminated, unidirectional composite tape. The stiffener includes a void that is reinforced by a filler wrapped with a structural adhesive. The surfaces of the preforms surrounding the void include a layer of composite fabric which is bonded to the filler by the adhesive, thereby increasing the toughness of stiffeners around the void and improving pull-off strength of the stiffener.
US09981442B2 Method for producing a multilayered preform and a preform
The invention relates to a multi-component injection molding method for producing a sleeve-shaped preform as well as to a perform which has at least two layers, said method comprising at least two process steps including at least two cavities and at least one injection mold core that can be used for both cavities, and wherein during the first process step, the first layer which has at least one first and at least one second area extending partially in the circumferential direction of the preform, is injected onto the injection mold core within the first cavity, with the second area having a substantially lower layer thickness than the first area, and during the second process step, the second layer is deposited on the first layer which is located on the injection mold core in the second cavity in such a way that only the second area of the first layer is completely covered by the second layer, or during the first process step, the first area of the first layer is deposited partially on the injection mold core within the first cavity, with the remaining areas being covered by the second layer during a second process step within a second cavity.
US09981437B2 Article of footwear with first and second outsole components and method of manufacturing an article of footwear
A sole structure for an article of footwear comprises a midsole including a polymeric bladder element enclosing a fluid-filled interior cavity, a first outsole component secured to a bottom surface and to a side surface of the polymeric bladder element, and a second outsole component. The first outsole component includes a first base, and a wall integral with the first base. The second outsole component includes a second base secured to the first base, and a wall integral with the second base and secured to the outer surface of the wall of the first outsole component. A method of manufacturing the article of footwear includes thermoforming the bladder element and the first outsole component, and securing the second outsole component to the first outsole component.
US09981435B2 Reusable lens molds and methods of use thereof
The present invention general related to a method and a reusable mold for making a contact lens, comprising a first mold half having a first mold surface in contact with a silicone containing lens forming composition and a second mold half having a second mold surface in contact with the lens forming composition. The first mold half and the second mold half are configured to receive each other such that a cavity is formed between the first mold surface and the second mold surface. The cavity defines the shape of a contact lens to be molded. The lens forming composition is polymerizable and/or crosslinkable by actinic radiation. The reusable mold has at least one of the mold halves is made from chalcogenide glasses, Zinc Selenide or Zinc Sulfide.
US09981433B2 Methods for modifying wind turbine blade molds
The present disclosure is directed methods for modifying molds of rotor blades of a wind turbine. In certain embodiments, the blade mold is constructed, at least in part, of a thermoplastic material optionally reinforced with a fiber material. In one embodiment, the method includes identifying at least one blade mold addition for the mold of the rotor blade and positioning the blade mold addition at a predetermined location of the mold of the rotor blade. Further, the blade mold addition is constructed, at least in part, of a thermoplastic material. Thus, the method includes applying at least one of heat, pressure, or one or more chemicals at an interface of the blade mold addition and the mold so as to join the blade mold addition to the mold. In further embodiments, the methods described herein are also directed repairing thermoplastic blade molds.
US09981430B2 Press moulding method
A method of press moulding a moulding material to form a moulded part of fiber-reinforced resin matrix composite material, the method comprising the steps of: i. providing a mould tool having a lower mould part and an upper mould part, the upper mould part having a first moulding surface for moulding a first moulded surface of the moulded part and the lower mould part having a second moulding surface for moulding a second moulded surface of the moulded part; ii. providing a multilaminar panel of moulding material comprising at least one layer of fibers and at least one layer of resin, the multilaminar panel having first and second opposite major surfaces, a surface resin layer of the multilaminar panel being at or adjacent to the first major surface and a dry fiber layer of the multilaminar panel forming the second major surface; iii. locating the moulding material in the mould tool by disposing the second major surface on the second moulding surface of the lower mould part, the lower mould part being at an elevated temperature as compared to the temperature of the moulding material; iv. closing the mould tool to define a substantially closed mould cavity containing the moulding material; v. applying pressure to the moulding material in the mould cavity to configure the moulding material in a fully moulded shape, and after the applying pressure step v the resin in the multilaminar panel fully impregnates the dry fibers; and vi. substantially fully curing the resin to form a moulded part from the moulding material.
US09981429B2 Press moulding method
A method of press molding a molding material to form a molded part of fiber-reinforced resin matrix composite material, the method comprising the steps of:i. providing a mold tool having a lower mold part and an upper mold part, the upper mold part having a first molding surface for molding a first molded surface of the molded part and the lower mold part having a second molding surface for molding a second molded surface of the molded part; ii. providing a multilaminar panel of molding material comprising at least one layer of fibers and at least one layer of resin, the multilaminar panel having first and second opposite major surfaces; iii. locating the molding material in the mold tool; iv. progressively closing the mold tool to define a substantially closed mold cavity containing the molding material, the closing step including: a. a preliminary closing phase to achieve mutual engagement between the lower and upper mold parts, b. a secondary closing phase after engagement between the lower and upper mold parts with the mold tool partially closed to define a closed intermediate cavity containing the molding material, the closed intermediate cavity being larger than the molded part and the first molding surface of the upper mold part being spaced from the first major surface by a spacing distance, in the secondary phase air being at least partially evacuated from the closed intermediate cavity while the first molding surface of the upper mold part is spaced from the first major surface to provide a vacuum pressure, and c. a tertiary closing phase after the vacuum pressure has been provided in the closed intermediate cavity, the tertiary phase having: I. a first stage prior to both the first molding surface contacting the first major surface and the second molding surface contacting the second major surface, and II. a second compression stage after both the first molding surface has contacted the first major surface and the second molding surface has contacted the second major surface, the closure speed of relative movement between the lower and upper mold parts being higher in the first stage than in the second compression stage; v. applying pressure to the molding material in the mold cavity to configure the molding material in a fully molded shape; and vi. substantially fully curing the resin to form a molded part from the molding material.
US09981427B2 Sensing device for three-dimensional printing object
A sensing device of a three dimensional object being printed is provided. The sensing device includes a roller, a ring shape equipment, a sensor, and a processor. The roller is utilized to perform planarization of the 3D printing object. The ring shape equipment has the same axial as the roller and rotates with the roller. The sensor is utilized to detect rotational speed of the ring shape equipment. The processor determines whether the roller is in contact with the 3D printing object according to the rotational speed of the ring shape equipment. Thereby, contact between the roller and the 3D printing object may be determined without disposed sensor on the roller.
US09981422B2 Cam based leveling assembly for three-dimensional object printing
A three-dimensional object printer comprises a conveyor having a surface configured to convey a three-dimensional object in a first direction; a leveling assembly configured to level a surface of the three-dimensional object as the conveyer conveys the three-dimensional object in the first direction, the leveling assembly comprising (i) a member, (ii) a roller connected to the member having a cylindrical shape, the roller having an outer surface that moves upon the surface of the three-dimensional object to level a surface of the three-dimensional object, and (iii) an actuator arranged near the member, the actuator being configured to mechanically interact with the member to move the roller with respect to the planar surface of the conveyer; and a controller configured to, as the outer surface of the roller moves upon the surface of the three-dimensional object, operate the actuator to move the roller with respect the conveyer.
US09981417B2 Apparatus and method of manufacturing display apparatus
An apparatus for and a method of manufacturing a display apparatus are provided. The apparatus includes a first mold configured to accommodate a window; a second mold configured to accommodate a panel member and to bond the window and the panel member to each other; and a guide roller on the first mold. The second mold faces the first mold and has a variable shape. The guide roller is rotatable and is configured to maintain tension in the panel member as the window and the panel member are bonded to each other.
US09981416B1 Extruder with static mixer injector
Apparatus for injection of fluid into an extruder is provided, including a static mixer section with a pipe assembly coupled with the static mixer outlet and leading to the extruder barrel; the pipe assembly outlet and barrel injection opening have diameters less than the maximum internal diameter of the static mixer casing. The invention greatly simplifies the fluid injection apparatus used with extruders, while giving more efficient absorption of thermal energy with a minimum of environmental contamination, and the ability to inject multiple streams into the extruder.
US09981408B2 Fabrication and replication of polymer optical waveguides
Polymer optical waveguides can be produced by separating the processes into a distinct embossing process and a distinct UV exposure process. Separating the processes can create a more refined product and a more efficient process, thus eliminating the need for special polymer optical waveguide fabrication machinery.
US09981406B2 Drill bit
A drill bit has a shank, an intermediate shaft, and a cutting head and defines a longitudinal axis. The cutting head has a body having a front end, a rear end, and a peripheral sidewall, a primary cutting insert and a pair of auxiliary cutting inserts. The primary cutting insert is cross-shaped with a central portion with a cutting tip and four cutting arms each with a cutting edge extending radially outward from the central portion past the peripheral sidewall. The auxiliary cutting inserts are spaced radially outward from the central portion and circumferentially from the radial cutting arms, and have a cutting edge extending radially outward past the peripheral sidewall. A pair of primary dust egress slots and a pair of auxiliary dust egress slots are formed in the peripheral sidewall and configured to channel debris from the front end to the rear end of the body.
US09981405B2 Wood chipper, control system therefor, and method thereof
A wood chipper comprises a frame, an infeed system, a rotatable cutting system, and at least one feed wheel disposed between the infeed system and the cutting system to feed wood material to the cutting system. The wood chipper also includes a winch comprising a winch line having a first end, and a collar disposed adjacent the first end of the winch line. The wood chipper further includes a detector adapted to detect a first and a second position of the winch line, wherein the detector is adapted to allow operation of the at least one feed wheel and prohibit operation of the winch when the first position of the winch line is detected, and to allow operation of the winch and allow operation of the at least one feed wheel in a predefined manner when the second position is detected. The wood chipper further comprises a bypass for operation of the at least one feed wheel.
US09981404B2 Safety feeder
A safety feeder includes a transmission system including a drive shaft having a rotating axis on a phantom axis, and a coupling system connecting to the drive shaft and configured to rotate with the drive shaft simultaneously. The coupling system includes a drive line and a tube covering the drive line. The drive line includes an end thereof connecting to the drive axle.
US09981402B2 Circular Saw Miter System
A circular saw miter system for includes a circular saw that has a guide and a blade. A stand is provided and the stand may be positioned on a support surface. The stand may have a board placed thereon. A miter is removably coupled to stand and the miter may position the board at a selected angle on the stand. A pair of tracks is provided and each of the tracks is coupled to the stand. The circular saw is slidably coupled to the tracks and the circular saw may be manipulated. Each of the tracks is positioned above the miter. Thus, the circular saw may cut the board at the selected angle.
US09981386B2 Method for controlling a manipulator device
A manipulator-device controlling method including: a step of receiving manipulation signals for manipulators; a step of calculating a target position of a joint on the basis of the manipulation signals; steps of calculating a maximum distance between the manipulators when the joint is assumed to be placed at the target position; a step of comparing the maximum distance with a predetermined threshold; a step of moving the joint to the target position in the case in which the maximum distance is equal to or less than the predetermined threshold; and a step of stopping the movement of the joint in the case in which the maximum distance is greater than the predetermined threshold.
US09981383B1 Real-time trajectory generation for actuators of a robot to reduce chance of collision with obstacle(s)
Methods, apparatus, systems, and computer readable media are provided for real-time generation of trajectories for actuators of a robot, where the trajectories are generated to lessen the chance of collision with one or more objects in the environment of the robot. In some implementations, a real-time trajectory generator is used to generate trajectories for actuators of a robot based on a current motion state of the actuators, a target motion state of the actuators, and kinematic motion constraints of the actuators. The acceleration constraints and/or other kinematic constraints that are used by the real-time trajectory generator to generate trajectories at a given time are determined so as to lessen the chance of collision with one or more obstacles in the environment of the robot.
US09981382B1 Support stand to reorient the grasp of an object by a robot
An example system includes a robotic device having a robotic manipulator and a support stand. The support stand may receive an object placed thereon in a given orientation and maintain the given orientation. The robotic manipulator may pick up an object in a first orientation with respect to the robotic manipulator and determine a target pose for the object. Based on the determined target pose, a control system may determine to reorient the object with respect to the robotic manipulator using the support stand. The robotic manipulator may place the object on the support stand in a particular orientation and pick up the object, disposed on the support stand in the particular orientation, in a second orientation with respect to the robotic manipulator. While the object is held in the second orientation with respect to the robotic manipulator, the robotic device may move the object to the target pose.
US09981379B1 Detachable support member for robot gripper
An example robotic gripping device includes two opposable gripping fingers and at least one actuator configured to move the two opposable gripping fingers towards and away from each other within a plane of motion. The robotic gripping device further includes a gripper base coupled to the two opposable gripping fingers, where the gripper base comprises an attachment interface. The robotic gripping device further includes a detachable elongated support member that mates with the attachment interface of the gripper base, such that when the elongated support member is attached to the attachment interface of the gripper base, the elongated support member extends parallel to the plane of motion of the two opposable gripping fingers.
US09981378B2 Handheld robot operation unit with an adapter device for a mobile terminal device
A handheld robot operation unit comprises a basic safety control device, a mobile terminal device, and a holder configured to mount the mobile terminal device on the basic safety control device. The holder comprises at least one adapter device configured to mechanically connect the mobile terminal device to the basic safety control device.
US09981377B2 Flexible robotic actuators
Systems and methods for providing flexible robotic actuators are disclosed. Some embodiments of the disclosed subject matter include a soft robot capable of providing a radial deflection motions; a soft tentacle actuator capable of providing a variety of motions and providing transportation means for various types of materials; and a hybrid robotic system that retains desirable characteristics of both soft robots and hard robots. Some embodiments of the disclosed subject matter also include methods for operating the disclosed robotic systems.
US09981369B2 Tensioning device for expanding a threaded bolt
A tensioning device for stretching a threaded bolt by applying tension to the threaded portion of the threaded bolt has a base and a support tube surrounding the threaded bolt and supported on the base. A cylinder housing is arranged as an axial extension on the support tube. A piston is moveably arranged in the cylinder housing and delimits together with an inner wall of the cylinder housing a hydraulic operating chamber. An interchangeable bush is rotatable relative to the piston and can be entrained axially by the piston. The interchangeable bush has an internal thread to establish a screw connection to the threaded portion. A device for path and/or position detection with first and second interacting elements is provided. The first element is fastened to the at least one piston and faces the cylinder housing. The second element is fastened to the cylinder housing and faces the piston.
US09981368B2 Suspension bushing service tool and method of use
A bushing service tool kit includes a clamping plate, head plate, and a mounting plate for a hydraulic cylinder, as well as a clamping member. An alignment member is mounted on one side of a bushing that is mounted in a bushing mount and that is to be replaced, and the clamping plate is mounted over the alignment member. The head plate is mounted on an opposite side of the bushing, and the clamping member clamps the head plate and clamping plate toward each other to clamp the bushing mount therebetween. The mounting plate, with a hydraulic cylinder mounted thereon, is mounted on the clamping member facing toward the clamping plate, whereby the hydraulic cylinder is aligned with the bushing. The cylinder can then be operated to remove the bushing and install a replacement.
US09981363B2 Open wrench
An open wrench includes a head having a handle and a driving portion which has an opening. A first layer, a second layer, a third layer and a fourth layer are formed on each of the top and the bottom of the driving portion. The first layer and the second layer are located along the U-shaped opening of the head. The top face of the second layer is smaller than that of the first layer. The third layer extends from the middle portion of the first layer, and the fourth layers extends from the middle portion of the second layer. The top face of the fourth layer is smaller than that of the third layer. The open wrench is light in weight and strong in structure, and is able to output significant torque to objects.
US09981355B2 Above plate coolant containment and recovery system
A machine is provided, including at least one cutting tool in the form of cutting head with coolant supplied for machining parts from flat material, wherein the machine also includes a coolant containment and recovery system which includes: a waste removal apparatus, a coolant guard having at least one wall bounding a containment forming area, wherein the coolant guard is fluidly connected to the waste removal apparatus, wherein in use: the coolant guard is located upon a plate to be machined; and the containment forming area becomes a containment area, within which the cutting tool and coolant are both located during the machining process, so that used coolant can be removed.
US09981354B2 Guide for cutting paving slabs
A guide for cutting paving slabs comprises: a guide member (1) for guiding a cutting tool; a clamping means (5, 6); and a locator (3). The clamping means comprises a spindle (5) which passes through an opening in the guide member and connects to the locator. The clamping means is adjustable to adjust the position of the spindle relative to the guide member thereby to adjust the distance between the locator and the guide member.
US09981352B2 Maintenance tool and method for a split friction bearing assembly and rotary machine using the same
The tool is designed to carried out maintenance operations on a bearing assembly comprising a bushing split into at least two shells; the maintenance tool comprises a device arranged to act on and rotate the bushing shells. In particular, the device comprises a slide and a pin; the slide has a hole transversal to its sliding direction and the pin is slidably mounted inside the hole and protrudes from the hole; in a first operating position the pin acts on a shell and in a second operating position the pin does not act on any shell. The method provides to rotate the bushing shells without rotating the supported shaft, and to carry out maintenance operations on a shell at a time while leaving the shaft supported by the other shell.
US09981350B2 Welding flux used for austenitic stainless steel
The present disclosure provides a welding flux used for austenitic stainless steel, which includes 20-40 wt. % SiC, 20-30 wt. % SiO2, 15-25 wt. % MoO3, 2-15 wt. % TiO2, 2-10 wt. % NiO, and 1-5 wt. % MgO. As such, the welding flux forms a soundness weld with high D/W ratio and surface hardness.
US09981348B2 Solder alloy and mounted structure using same
A solder alloy is substantially Ag-free and has desirable neat-resistance fatigue characteristics in a high-temperature environment as high as 150° C., even when used for soldering of electronic components having no leads. The solder alloy contains Sb, In, Cu, and Bi, and Sn accounting for the remainder, and satisfies the following formulae: 0.5≤[Sb]≤1.25 0.66[Sb]+4.16≤[In]≤6.0 0.5≤[Cu]≤1.2 0.1≤[Bi]≤0.5, wherein [Sb], [In], [Cu], and [Bi] represent the contents of Sb, In, Cu, and Bi, respectively, in mass %.
US09981347B2 Indium-tin-silver based lead free solder
Indium-tin-silver alloys suitable for use as a lead free solder are described herein. The alloys may comprise primarily indium or comprise primarily tin. The alloys may further include copper, nickel, and iron or copper, antimony, and zinc. The composition can be used to solder an electrical connector to an electrical contact surface on a glass component. Methods of forming the alloys are also described herein.
US09981341B2 Smart additive manufacturing system (SAMS)
An additive manufacturing process is monitored, in situ, using optical emission spectroscopy to analyze the composition, phase transformation or manufacturing defects. The system or method may include an analysis of contours of the plasma line intensity, or pre-processing of the plasma spectral line including signal-to-noise ratio analysis, baseline removal, line identification, line de-convolution and fitting. Improvements may additionally involve consideration of plasma parameters such as plasma spectral line intensity, line ratio, plasma temperature and electron density using high-resolution optical emission spectroscopy in both visible and ultraviolet regions. Parameters of the plasma may be determined using an intensity ratio of the ions or atoms emission lines, a FWHM of the line profile for electron density estimation, or a Boltzmann plot for plasma temperature estimation. One or more techniques may be used to monitor when there is a lack of deposition.
US09981340B2 Laser ablation method for treating a copper alloy containing metallic surface and increasing hydrophobicity
A method of treating a metallic surface comprising a copper alloy, such as phosphor bronze, whereby the metallic surface is ablated by directing a laser beam with a diameter of 200-400 μm produced by a CO2 laser with a pulse frequency of 1200-1800 HZ onto the metallic surface, and a N2 assist gas is concurrently applied with a pressure of 550-650 KPa co-axially with the laser beam to form an ablated metallic surface comprising microgrooves with Cu3N present on a surface of the microgrooves, wherein the ablated metallic surface has a higher surface hydrophobicity than the metallic surface prior to the ablating.
US09981337B2 Diagnostic system and method for testing integrity of stack during ultrasonic welding
A method for testing the integrity of a stack during ultrasonic welding, includes the steps of: (i) ultrasonically welding two or more work pieces with a stack, the stack including a convertor and a horn; (ii) measuring a frequency profile based on a vibration of the horn during the welding step; and (iii) comparing the measured frequency profile to a standard frequency profile to obtain an error rate, the error rate being indicative of a difference between the measured frequency profile and the standard frequency profile. A system employing the aforementioned method is also provided.
US09981333B2 Method for manufacturing rotary article by cold metal transfer welding deposition and rotary article as manufactured
A method for manufacturing a rotary article comprises: providing a cold metal transfer welding apparatus comprising a welding torch; providing a rotary substrate; providing a digital representation of the rotary article having at least one internal flo passage; defining a welding path on the rotary substrate based on the digital representation; rotating the rotary substrate while depositing a filler metal layer by layer on the welding path of the rotary substrate to form the rotary article; and separating the rotary substrate from the rotary article.
US09981326B2 Table saw
Table saws and table saws designed to incorporate safety systems are disclosed. The table saws may include vertical slide elevation mechanisms positioned toward the rear of the saw and constructed so that an arbor block and blade can retract when a safety system detects an unsafe condition. Other table saw parts and components are also disclosed.
US09981324B2 Milling tool
A milling tool has a basic body rotatable about a center axis, and including an outside, which includes a pair of opposite front and back sides, as well as a peripheral envelope surface. The body is equipped with a plurality of replaceable cutting inserts. The basic body includes an inner hollow space having an internal limiting surface, in which there collectively mouth a plurality of bores. The bores also mouth in the outside. Each cutting insert is mounted on an outer end of an ejector, which is rectilinearly movable in the individual bore and has an inner end accessible from the hollow space, and which interacts with a compressible force generator, to pull the same into the bore. By mounting the cutting inserts on ejectors, which simultaneously are accessible from a common hollow space, the cutting inserts can be replaced fast and easily, and possibly also be indexed.
US09981323B2 Double-sided tangential cutting insert and cutting tool system using the same
A double-sided tangential cutting insert, as well as a tool holder system that carries a plurality of the double-sided tangential cutting inserts, that has a peripheral side shape, as viewed from one of said cutting rake faces, that includes a pair of generally identical opposing main cutting edges wherein each of the main cutting edge comprises a substantially straight main cutting edge portion and an adjoining convex main cutting edge portion. The convex main cutting edge portion is truncated by an adjacent convex minor side face so as to define a generally sharp edge and a point of truncation. The peripheral side shape further includes a pair of opposing full nose cutting edges with a nose cutting radius; and a pair of opposing convex minor cutting edges with a minor cutting edge radius. The minor cutting edge radius is at least about four times greater than the nose cutting radius.
US09981319B2 Tool clamping system
The invention discloses a tool clamping system comprising a tool holder for clamping a tool, said tool holder being configured for being driven rotatingly; a tool secured to the tool holder; a tool shaft carried by the tool; at least one cutting edge carried by the tool; at least one piezo element for generating a voltage from mechanical vibration energy of the rotating tool clamping system; and at least one delay element selected form the group consisting of an inductor and a capacitor being connected to the at least one piezo element so as to form an electrical oscillating circuit, wherein the oscillating circuit is configured for monitoring at least one operating parameter of the tool clamping system.
US09981318B2 Lathe for machining a workpiece and related methods and toolholders
A lathe has a plurality of turret positions with at least one having a toolholder, a pair of blades projecting from one end of the toolholder with the toolholder structured to assume a first position with a first blade machining said workpiece which is rotating in a first direction and a second position with a second blade structured to assume a second position with the workpiece rotating in the other direction. The toolholder remains fixed during machining. Related methods and toolholders are disclosed.
US09981314B2 Direct writing for additive manufacturing systems
There are provided techniques for direct printing material into parts made by additive manufacturing, such as parts made by laser sintering. The direct printed material may be a metal, elastomer, ceramic, or any other material. Further, the direct printed material is typically different than the laser sintering material. Other aspects of the invention include using direct printed materials in the laser sintered parts to improve part strength, provide multi-materials, selectively provide electrical conductivity, and/or provide other desirable features to the parts.
US09981312B2 Three-dimension printer with mechanically scanned cathode-comb
A 3-D printer scalable to large sizes employs a combination of mechanical and electrical scanning of a linear array of electron beams that operate to melt material of a powder bed. A housing holding the electron beam sources may be maintained at a high vacuum and positioned close to a print surface to minimize electron travel in a softer vacuum surrounding a print bed.
US09981311B2 Bottom-pouring-type ladle, and melt-pouring method using it
A method for pouring a melt using a bottom-pouring-type ladle comprising a melt-pouring nozzle and a stopper rod, comprises an opening step, in which the stopper rod is separate from the nozzle; a first closing step, in which the stopper rod moves downward, such that a lower end portion of the stopper rod comes into contact with a tapered surface of the nozzle when the horizontal distance between their center axes becomes 2 mm or more; and a second closing step, in which a lower end portion of the stopper rod further moves downward along the tapered surface of the nozzle to close the nozzle.
US09981309B2 Wheel mold spraying apparatus
The present invention discloses a wheel mold spraying device, which is composed of a frame, a servo motor, a servo electric cylinder, a hollow shaft, a nozzle and the like. Four side molds of a wheel are respectively placed on four slide plates; hand wheels are rotated to adjust the slide plates to proper positions through lead screws and guide rails; the servo motor drives the rotation of the hollow shaft and the nozzle through belt wheels and a synchronous belt, and the nozzle is automatically opened; and through guide posts, the servo electric cylinder lifts the nozzle to the top end while rotating, in which case the process of spraying for the four side molds can be completed.
US09981308B2 Method for manufacturing a core for moulding a blade
A method of manufacturing a core for molding a blade of a turbomachine, including placing a flexible ceramic sheet in a cavity of a mold in such a way as to shape the ceramic sheet, introducing a ceramic paste into the cavity of the mold, the ceramic paste forming at least one frame in contact with the ceramic sheet, and co-sintering the ceramic sheet and the frame in such a way as to rigidly join together the ceramic sheet and the frame, the frame maintaining the shape of the ceramic sheet given by the mold during the preceding co-sintering phases.
US09981303B2 Tube expander for heat exchanger coil units
A tube expander for heat exchanger coil units according to which a tubular expansion process is conducted. In one aspect, the tube expander includes a fixture, which includes a back unit and first and second door assemblies movably connected thereto. One or more heat exchanger coil units are adapted to be connected to each of the first and second door assemblies. In another aspect, the fixture is adjustable to accommodate different heat exchanger coil units. In yet another aspect, the tubular expansion process is not permitted when the first or second door assembly is closed and a sensor does not sense the presence of a latch bar.
US09981300B2 Floatingly mounted column frame for wobble compensation movement
The present invention relates to a column frame (20) for tools of stamping and forming technology, consisting of a head plate (1) and a base plate (2) between which guide columns (3) for guiding a guide plate (4) are arranged, and the guide columns (3) defining a movement direction Z for the guide plate (4), characterized in that the guide plate (4) is mounted elastically on the guide columns (3) on guide plate-side guide units (5) in such a way that the guide plate (4) can wobble about an axis parallel to the Z direction.
US09981299B2 Punch apparatus
A punch apparatus includes a drive unit and a driving force transmission mechanism that transmits a driving force output by the drive unit to a rod. In the driving force transmission mechanism, a cam groove is formed in a cam block connected to a piston rod, and a rotating roller, which is pivotally supported on a displacement body connected to the rod, is inserted through the cam groove. The cam groove has a first groove portion and a second groove portion, which are inclined at predetermined angles of inclination with respect to the displacement direction of the cam block. When the rod is made to descend toward the workpiece, the rotating roller moves from the second groove portion into the first groove portion, which has a small angle of inclination, whereby the driving force transmitted to the rod is boosted.
US09981296B2 Method and device for producing an internally and externally toothed pot-shaped sheet metal part using a forming head
A method for producing an internally and/or externally toothed pot-shaped sheet metal part having teeth extending toward the pot center axis, wherein an un-toothed pot-shaped sheet metal part is inserted into a die and then, by means of a relative movement between the sheet metal part and associated profile rollers, a profile is rolled onto the pot-shaped sheet metal part by the profile rollers applied to the sheet metal part and thus alternating internal and external gear teeth are applied to the sheet metal part, wherein the profile rollers form the sheet metal part oriented radially from the inside toward the outside, in that the profile rollers roll along the inner circumference of the sheet metal part.
US09981289B2 Screen panel locking system
A screening apparatus includes elongate beams and screen panels mounted to the beams to form a broad screening surface. Each of the panels are mounted so that side edges of adjacent panels are in facing relationship. Each panel is mounted to a pair of beams to bridge between two adjacent beams. The panels are mounted to the beams by fixing members. The fixing members have a pair of upstanding rails that are spaced apart to define a longitudinal gap between them. The panels are mounted to the beams by cooperation between the side edges with a rail of a fixing member. Cover strips extend along the beams and include a cover portion and a locking portion. The cover portion bears against an upper surface of a pair of adjacent panels and the locking portion bears against facing surfaces of the rails to resist movement of the rails towards each other.
US09981287B2 Low VOC, water-based coating compositions suitable for protecting metal containing substrates including food and beverage packages
Coating compositions and methods of using these compositions to form tough, abrasion resistant, and water resistant coatings on metal-containing substrates are described. Coating compositions are derived from one or more ingredients comprising at least one copolymer, referred to herein as Copolymer I, that preferably comprises (a) one or more repeating units (Repeating Unit(s) A) comprising at least one hydrophilic ester functionality and at least one polar functionality; and (b) one or more additional kinds of copolymerizable repeating units (Repeating Unit(s) B). Preferably, repeating Unit(s) A are a residue of an unsaturated monoester of a diacid or anhydride thereof having a carbon-carbon double bond, wherein at least one hydrophilic ester is pendant from a first carbon of the carbon-carbon double bond and at least on polar group is pendant from the second carbon of the carbon-carbon double bond. The monoester preferably is the reaction product of one or more water soluble or water dispersible alcohols with an unsaturated diacid or anhydride thereof.
US09981283B2 Discharge device for paste-like materials with separately formed adapter for connecting a container to a base body
This invention relates to a discharge device of the dispenser gun type, which is suitable in particular for discharging semi-solid materials such as e.g. bone replacement materials. The discharge device comprises an adapter (400) which is removably attached to a main body (110) of the discharge device. A fastening structure for attachment of a container (300) is formed on the adapter substantially along a proximal direction (C) contrary to the feed direction (A). As a result various types of containers can be fastened to the machine without the need to change the mechanism of the device. The container can be provided on both ends with identical external threads and can be closed by closure caps in order to enable intuitive handling. In order to improve access to points which are difficult to reach, the container may be in the form of a curved pipe or may be formed flexibly. The piston rod (200) of the discharge device is then also formed flexibly.
US09981281B2 Spray booth with shallow depth under section and wet scrubber
A spray booth module having a plurality of wet scrubbers. The wet scrubbers being located beneath an area where over spray is generated and enabling the under section exhibits a reduced vertical depth relative to known under sections of comparable spray booths.
US09981277B2 Rotary module
A device (10) for applying a fluid to a moving substrate (36) includes a nozzle head (15a, 15b, 15c, 15d) with an inlet opening (26, 26c) and an outlet opening (29a, 29b, 29c, 29d). The device further includes a supply station (11) with a fastening surface (17) with a mouth region (20a) of a fluid duct. The nozzle head is arranged so as to be pivotable relative to the fastening surface about a pivot axis (38a). The inlet opening (26, 26c) and the mouth region (20a) of the fluid duct are arranged in alignment along the pivot axis (38a).
US09981276B2 Sprinkler head nozzle assembly with adjustable arc, flow rate and stream angle
A sprinkler head nozzle assembly in accordance with an embodiment of the present invention includes a housing including an inlet for pressurize water and an outlet downstream of the inlet, a valve member, operable to extend and reduce an arcuate opening at the outlet of the housing, wherein the size of the arcuate opening indicates the arc of coverage of the sprinkler head nozzle assembly and a rotating distributor, mounted on a central shaft extending through the housing and the valve member, and operable to deflect a flow of water from the arcuate opening out of the nozzle assembly.
US09981275B2 Separator with direct drive and coolant system integrated into drive housing
A separator includes: a centrifugal drum; a drive spindle, where the drive spindle is rotatably mounted in a drive housing by a neck bearing and a foot bearing, and where the drive housing encloses a drive chamber; an electric motor which has a stator and a motor rotor, where the motor rotor is disposed on the drive spindle, where the stator is fixedly connected to the drive housing, where an air gap exists between the stator and the motor rotor, and where the stator and the motor rotor are arranged between the neck bearing and the foot bearing; a lubricating system for lubrication of the neck bearing and the foot bearing; and a coolant system; where the stator has a flange section which is disposed on a collar section of the drive housing.
US09981273B2 Negative dielectrophoresis for selective elution of immuno-bound particles
The procedure of dielectric electrophoresis (dielectrophoresis or DEP) utilizes field-polarized particles that move under the application of positive (attractive) and/or negative (repulsive) applied forces. This invention uses negative dielectric electrophoresis (negative dielectrophoresis or nDEP) within a microchannel separation apparatus to make particles move (detached) or remain stationary (attached). In an embodiment of the present invention, the nDEP force generated was strong enough to detach Ag-Ab (antigen-antibody) bonds, which are in the order of 400 pN (piconewtons) while maintaining the integrity of the system components.
US09981272B2 Techniques for transporting synthetic beads or bubbles in a flotation cell or column
Apparatus featuring synthetic bubbles or beads and a flotation stage. The synthetic bubbles or beads are configured with a polymer or polymer-based material functionalized to attach to the valuable material in a mixture to form at least some enriched synthetic bubbles or beads having the valuable material attached thereto, and also configured to be transported through the mixture based at least partly on a characteristic of the synthetic bubbles or beads. The flotation stage has the mixture containing valuable material, and is configured to receive the synthetic bubbles or beads and to provide the at least some enriched synthetic bubbles or beads having the valuable material attached thereto based at least partly the characteristic of the synthetic bubbles or beads.
US09981268B2 Safety shredder with mechanical bin-full device
A mechanical bin-full device for a paper shredder with a bin, having a curved, perforated T-blade sensor on a cylindrical body partially covered with a metal sheet. The T-blade is pendent into the bin. Metal contacts are placed on the paper shredder near the metal sheet, forming a switch, which is coupled to a motor control circuit for the shredder motor. The T-blade is pushed by paper shreddant and rotates the cylinder body as paper shreddant fills the bin. When the bin becomes full, the T-blade is positioned so that the metal contacts touch the metal sheet, closing the control circuit switch, and causing the motor to cease operating. The control circuit can include a microcontroller coupled to the motor, or a transistor-based driver coupled to a motor relay.
US09981265B2 Microfluidic mixing device
A microfluidic mixing device comprises a main channel and a number of secondary channels extending from a portion of the main channel and entering another portion of the main channel. A number of actuators are located in the secondary channels to pump fluids through the secondary channels. A microfluidic mixing system comprises a microfluidic mixing device. The microfluidic mixing device comprises a main fluid mixing channel, a number of main channel actuators to pump fluid through the main fluid mixing channel, a number of secondary channels fluidly coupled to the main fluid mixing channel, and a number of secondary channel actuators to pump fluids through the secondary channels. The microfluidic mixing device also comprises a fluid source, and a control device to provide fluids from the fluid source to the microfluidic mixing device and activate the main channel actuators and secondary channel actuators.
US09981263B2 Flow control apparatus for sample fluids
A flow control apparatus for facilitating treatment of a fluid containing a sample for analysis, includes: a body having spaced ends and defining a fluid flow passage arrangement that extends between the ends. The fluid flow passage arrangement includes two flow paths that are configured in parallel, merge within the body at least once, and respectively contain a one-way check valve and a medium selected to treat or modify sample-containing fluid flowing therethrough.
US09981258B2 Integrated LNT-TWC catalyst
A layered catalyst composite for the treatment of exhaust gas emissions, effective to provide lean NOx trap functionality and three-way conversion functionality is described. Layered catalyst composites can comprise catalytic material on a substrate, the catalytic material comprising at least two layers. The first layer comprising rare earth oxide-high surface area refractory metal oxide particles, an alkaline earth metal supported on the rare earth oxide-high surface area refractory metal oxide particles, and at least one first platinum group metal component supported on the rare earth oxide-high surface area refractory metal oxide particles. The second layer comprising a second platinum group metal component supported on a first oxygen storage component (OSC) and/or a first refractory metal oxide support and, optionally, a third platinum group metal supported on a second refractory metal oxide support or a second oxygen storage component.
US09981255B2 Ceramic honeycomb structure and its production method
A ceramic honeycomb structure comprising large numbers of cells partitioned by porous cell walls, the cell walls having (a) porosity of 50-80%, and when measured by mercury porosimetry, (b) a median pore diameter being 25-50 μm, (c) (i) a cumulative pore volume in a pore diameter range of 20 μm or less being 25% or less of the total pore volume, (ii) a cumulative pore volume in a pore diameter range of more than 20 μm and 50 μm or less being 50% or more of the total pore volume, and (iii) a cumulative pore volume in a pore diameter range of more than 50 μm being 12% or more of the total pore volume.
US09981254B2 Pre-carburized molybdenum-modified zeolite catalyst and use thereof for the aromatization of lower alkanes
The present invention relates to a method for producing a zeolite catalyst useful for aromatization of a lower alkane, a zeolite catalyst useful for aromatization of a lower alkane obtainable by said method and a process for aromatization of a lower alkane using the zeolite catalyst of the present invention.
US09981248B2 Polycondensation catalyst for producing polyester and method for producing polyester using the same
The invention provides a polycondensation catalyst for producing polyester by an esterification reaction or a transesterification reaction between a dicarboxylic acid or ester-forming derivative thereof and a glycol, wherein the polycondensation catalyst comprises particles of a solid base having on their surfaces either a coat layer of titanic acid in an amount of from 0.1 to 50 parts by weight in terms of TiO2 per 100 parts by weight of the solid base, or an inner coat layer of an oxide of at least one element selected from silicon, aluminum and zirconium or a composite oxide of at least two elements selected from silicon, aluminum and zirconium in an amount of from 1 to 20 parts by weight per 100 parts by weight of the solid base and an outer coat layer of titanic acid in an amount of from 0.1 to 50 parts by weight in terms of TiO2 per 100 parts by weight of the solid base.
US09981245B2 Method and apparatus for zirconium oxide recharging
Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer of a sorbent material such as zirconium oxide and/or zirconium phosphate in a sorbent cartridge. The methods and apparatuses include passing solutions containing aqueous basic solutions through the zirconium oxide. The apparatus allows for recharging the zirconium oxide, and also for recharging zirconium phosphate, wherein the sorbent materials are contained in reusable sorbent modules.
US09981240B1 Devices for charge-titrating particle assembly, and methods of using the devices
Methods to fabricate tightly packed arrays of nanoparticles are disclosed, without relying on organic ligands or a substrate. In some variations, a method of assembling particles into an array comprises dispersing particles in a liquid solution; introducing a triggerable pH-control substance capable of generating an acid or a base; and triggering the pH-control substance to generate an acid or a base within the liquid solution, thereby titrating the pH. During pH titration, the particle-surface charge magnitude is reduced, causing the particles to assemble into a particle array. Other variations provide a device for assembling particles into particle arrays, comprising a droplet-generating microfluidic region; a first-fluid inlet port; a second-fluid inlet port; a reaction microfluidic region, disposed in fluid communication with the droplet-generating microfluidic region; and a trigger source configured to trigger generation of an acid or a base from at least one pH-control substance contained within the reaction microfluidic region.
US09981239B2 Devices and methods for oligonucleic acid library synthesis
Devices and methods for de novo synthesis of large and highly accurate libraries of oligonucleic acids are provided herein. Devices include structures having a main channel and microchannels, where the microchannels have a high surface area to volume ratio. Devices disclosed herein provide for de novo synthesis of oligonucleic acids having a low error rate.
US09981236B2 Steam reforming
A process for the steam reforming of hydrocarbons comprises partially oxidizing a feedgas comprising a hydrocarbon feedstock with an oxygen-containing gas in the presence of steam to form a partially oxidized hydrocarbon gas mixture at a temperature >1200° C. and passing the resultant partially oxidized hydrocarbon gas mixture through a bed of steam reforming catalyst, wherein the bed comprises a first layer and a second layer, each layer comprising a catalytically active metal on an oxidic support wherein the oxidic support for the first layer is a zirconia.
US09981232B2 Reconfigurable mixing baffle for static mixer and method for making a static mixer
A mixing baffle for mixing a fluid flow in a static mixer includes a mixing element support structure extending along a longitudinal direction and a first set of moveable mixing elements coupled to the mixing element support structure. The first set of moveable mixing elements is formed in a first configuration and moves to a second configuration when the mixing baffle is inserted into a tubular conduit. In the second configuration, the first set of moveable mixing elements is optimized for mixing fluids and defines a plurality of undercuts that are difficult to mold. The mixing baffle may also include a second set of stationary mixing elements that interlace with the first set of moveable mixing elements when the first set of moveable mixing elements moves to the second configuration.
US09981230B2 Microfluidic devices
The present invention provides novel microfluidic substrates and methods that are useful for performing biological, chemical and diagnostic assays. The substrates can include a plurality of electrically addressable, channel bearing fluidic modules integrally arranged such that a continuous channel is provided for flow of immiscible fluids.
US09981229B2 Loop flow bubble-generating nozzle
There is provided a loop flow type bubble generation nozzle capable of improving the bubble generation efficiency compared to conventional nozzles without reducing the bubble generation efficiency even when liquid containing impurities is used. A loop flow type bubble generation nozzle 10 includes a tubular bottomed member 1 having a circular cross section and a tubular member 2 which is fitted into the other end side of the bottomed member 1. A substantially cylindrical space surrounded by the bottomed member 1 and the tubular member 2 serves as a loop flow type gas-liquid stirring and mixing chamber 6. The tubular member 2 has, on the center thereof, an inflow hole 7 which is capable of allowing liquid and gas to flow therein, and a first jet hole 8a and a second jet hole 8b which are capable of jetting liquid and gas. The inflow hole 7 is formed in a tapered shape whose diameter continuously expands from the first jet hole 8a toward the loop flow type gas-liquid stirring and mixing chamber 6. A plurality of cut-away parts 7a are formed on an end face of the inflow hole 7, the end face facing the loop flow type gas-liquid stirring and mixing chamber 6.
US09981228B2 Apparatus for producing a liquid concentrate from a dry material
An apparatus for converting a dry material into a liquid concentrate includes a mixing vessel having an outlet opening, a dispenser for dispensing a predetermined weight of a dry material at a predetermined drop rate onto a predetermined drop location within the vessel, an inlet pipe connectable to a source of liquid for introducing a liquid into the vessel; a sensor for sensing the volume of liquid within the vessel; a pump for supplying a pressurized flow of recirculating liquid to the vessel; and a first, a second and a third agitating nozzle mounted within the vessel. Each agitating nozzle is operative to produce a jet of liquid oriented in a predetermined direction within the vessel. The nozzles are cooperable to generate within the vessel a moving body of liquid into which a dry material dispensed into the vessel is able to dissolve or to disperse.
US09981227B2 Composite polyamide membrane having azo content and high acid content
A thin film composite polyamide membrane comprising a porous support and a thin film polyamide layer characterized by possessing: i) an azo (—N═N—) content of from 0.40% to 1.00%, as measured by pyrolysis gas chromatography; and ii) a dissociated carboxylate content of at least 0.40 mol/kg as measured by RBS at pH 9.5.
US09981224B2 Exhaust purification device
An exhaust purification device purifies an exhaust gas exhausted from an internal combustion engine. The exhaust purification device has a three-way catalytic agent that is located in an exhaust passage of the internal combustion engine and a particulate filter that is located downstream of the three-way catalytic agent in the exhaust passage and that collects an exhaust particulate. The particulate filter is provided with cells that includes sealed-inlet cells of which upstream ends are sealed and through cells through which an upstream side and a downstream side of the particulate filter communicate with each other. The particulate filter is arranged at a location where a temperature of the exhaust gas reaching an upstream end of the particulate filter is higher than or equal to a combustion temperature of the exhaust particulate, when the three-way catalytic agent is in an active state and when the internal combustion engine is operated.
US09981220B2 Exhaust gas clean-up and recovery system for fossil fuel fired power plant
A fossil fuel fired power plant exhaust gas clean-up and recovery system is provided to remove detrimental compounds/elements from the exhaust gas emitting from the power plant to protect the environment and to recover useful products from the cleaning solution. This is accomplished by directing the exhaust gas from the fossil fuel fired power plant through a single wet scrubber having a cleaning solution of a predetermined pH. The cleaning solution is composed of calcium carbonate and water. A recovery process is attached thereto to reclaim calcium carbonate, calcium sulfate, and carbon dioxide for reuse in the process and/or for commercial use.
US09981217B2 Air filtration equipment, screen window and window
An air filtration equipment, the air filtration equipment is installed in an ventilation area at an interface between indoor and outdoor spaces of a fixed space, the equipment including: a sensor configured to sense information on inhalable particles in outside air; at least one filtering layer configured to filter out inhalable particles in air entering from the ventilation area into the indoor space; and a control device connected with the sensor and the at least one filtering layer and configured to control the at least one filtering layer to expand according to the information sensed by the sensor, such that the expanded at least one filtering layer covers the ventilation area. Also, a screen window and a window are provided.
US09981216B2 Exhaust gas purification device and particulate filter
Particulate filter provided in the exhaust gas purification device includes: a wall-flow part having an inlet-side cell that is open only at an end on an exhaust gas inflow side, outlet-side cell adjacent to this inlet-side cell and is open only at an end on an exhaust gas outflow side, a porous wall partitions the inlet-side cell from the outlet-side cell; a straight-flow part having a through cell that penetrates the filter in axial direction and is open at the end on the exhaust gas inflow side as well as the end on the exhaust gas outflow side. In a cross section of the filter orthogonal to its axial direction, cross-sectional areas of the inlet-side cell and outlet-side cell present in an outer peripheral region of the cross section are larger than cross-sectional areas of the inlet-side cells and the outlet-side cell in a central region of the cross section.
US09981213B2 Air cleaner housing
An air cleaner housing is provided with a first case including an opening, a second case capable of opening and closing the opening of the first case, a clamp mechanism including a clamp that holds the second case in a state closing the opening of the first case, a filter element arranged between the first case and the second case, and a first closing stopper and a second closing stopper configured to interfere with each other when the second case is displaced from a predetermined position relative to the first case thereby stopping the second case from closing the opening of the first case. The first closing stopper and the second closing stopper are included in the clamp mechanism.
US09981212B2 Method for manufacturing porous graphene filter, porous graphene filter manufactured using same, and filter apparatus using porous graphene filter
Disclosed herein are porous graphene filters, each consisting of a carbon monoatomic layer having small holes formed therein during the graphene formation, a plurality of the porous graphene filters being used to selectively filter a specific material from a mixture of at least two different materials, a method for manufacturing the same, and a filtering apparatus using the same. The method comprises: separately forming a first graphene filter having a first hole of a first size and a second graphene filter having a second hole of a second size, during deposition of carbon atoms generated from a carbon source for formation of graphene, by substituting the carbon atoms, in part, with a substitution atom generated from a substitution source, the second size being larger than the first size; and arranging the first graphene filter and the second graphene filter in a filter body equipped with an inlet and an outlet.
US09981211B2 Apparatus for making and methods of making and using particle- and fiber-containing materials
Apparatus for making particle- and fiber-containing materials, such as a filter, are disclosed. Methods of making and using particle- and fiber-containing materials, such as a filter, are also disclosed. Particle- and fiber-containing materials are further disclosed.
US09981209B2 Thickener feed distributor
A feedwell comprising a plurality of holes disposed in a bottom thereof, at least some of the holes having a tube disposed thereabout which extends downward or otherwise away from an interior of the feedwell. Optionally, a large center hole can be provided and it can have a tube disposed around it. By providing a plurality of holes spread across a large portion of the bottom of the feedwell, lower velocity flow rates from the feedwell to a sedimentation chamber can be provided, thus reducing induced turbulence in the fluid within the sedimentation chamber, while still providing sufficient separation of the feedwell from the sedimentation chamber so that the contents of the feedwell can be properly and adequately mixed.
US09981207B2 Polymers useful as demulsifiers and clarifiers
A polymer useful as a flocculent, demulsifier or water clarifier may be selected from those having the general formula: wherein R is an alkyl group having from 3 to about 7 carbons and X is an integer having a value of at least two. The alkyl group may be linear or branched.
US09981206B2 Separator for oil well produced fluid, and separation device comprising the same
A separator for an oil well produced fluid comprises a housing and a tube group arranged within the housing. The tube group includes a plurality of horizontal pipes in a layered arrangement along a vertical direction, and a plurality of vertical pipes which allows adjacent layers of the horizontal pipes to be in fluid communication with each other. The plurality of horizontal pipes shares an inlet pipe in communication with the outside of the housing, and each of the horizontal pipes has a respective outlet. The separator is configured in such a manner that the horizontal pipes in an upper layer, a middle layer, and a lower layer are respectively used as oil pipes, water pipes, and sediment pipes.
US09981205B2 Purification device, and purification method
Provided is a purification device for purifying a useful substance (i.e., target substance) without using an acidic eluent. The purification device purifying the target substance comprises a column and a filler packed in the column. The filler contains a carrier, a temperature responsive polyamino acid bonded to the carrier, and a binding substance bonded to the temperature responsive polyamino acid and specifically bonding to the target substance.
US09981202B2 Rotary evaporator with mechanical foam breaker
A rotary evaporator for the vacuum distillation of a liquid is disclosed. The rotary evaporator contains an evaporator flask and a vapor feeder with an interior volume connected downstream of the evaporator flask. The rotary evaporator further contains a rotor that has a mechanical foam breaker within the interior volume of the vapor feeder. Further, a cooler is connected downstream of the vapor feeder.
US09981200B2 External mixing pressurized two-fluid nozzle and a spray drying method
Disclosed herein is an external mixing pressurized two-fluid nozzle for atomising a liquid by means of liquid pressure and gas, comprising an inner feed liquid pipe (1) extending axially between an upstream end and a downstream end, having a feed liquid conduit (2), a feed liquid inlet (3) positioned at the upstream end and a feed orifice (4) positioned at the downstream end, and a co-axial first gas pipe (5) extending radially outside the inner feed liquid pipe (1) and forming a first gas conduit (6) between the first gas pipe (5) and the inner feed liquid pipe (1), the first gas pipe (5) having a gas outlet slit (7) positioned at the downstream end. Said external mixing two-fluid nozzle provides a swirling motion of the gas, which combined with a pressurized feed liquid enables the production of spray dried powder at industrially applicable capacities with low energy consumption and a small particle size.
US09981199B2 Water purification apparatus and method
There is disclosed a water purification apparatus and method, related to desalinization. In an embodiment, a water purification apparatus and method includes at least one port for receiving airflow therethrough, at least one port for receiving salt water therethrough, at least one output for providing outflow of pure water vapor, and at least one output for proving outflow of a mixture of water, salt and air; and a plurality of chambers for evaporating the salt water into the airflow, at least one of the chambers forming a plurality of ports arranged in a plurality of rows. In an embodiment, a method includes providing airflow to a water purification apparatus; providing salt water to the water purification apparatus and method; forming a vortex in the airflow to evaporate water vapor from the salt water; and providing the water vapor in the airflow to a condenser so as to obtain pure water.
US09981194B1 Motion base for ride attraction or theater
In a theater or ride attraction, a motion base articulates a load-bearing seating platform by independently revolving two intermediate wedge-like rings to provide pitch, roll and yaw movements. Unlike flight simulator types of motion bases, these movements do not rely on substantially horizontally pivoting axes, and the resultant loads imparted to motive components. Rather the movements are provided by a circumferentially wedging action between the rings. The motion base has high load carrying capacity and reduced space requirements.
US09981193B2 Movement based recognition and evaluation
This disclosure relates generally to analysis of movement that is electronically captured and recognition of which movement was performed for purposes of evaluation. This type of motion capture, analysis and evaluation can have applicability across a number of fields, such as healthcare, entertainment, communication, and manufacturing. The recognition can occur once movement information collected from sensors is inputted into the system. The system can then analyze the movement information to determine what the movement is. In some games, such as sports games, movement recognition can provide feedback to a user about what they are doing. In other games, such as dance games, movement recognition can allow for users to dance a move from a set of moves providing for a more entertaining game.
US09981191B2 Native gameplay experience across platforms
An operating system (OS) platform-level gaming module that is integrated as part of an OS platform for a first wired and/or wireless communication device is operable to detect when a user installs a game written for the first wired and/or wireless communication device. The OS platform-level gaming module is operable to publish the game to a cloud when the installation of the game is detected and install the published game to at least a second wired and/or wireless communication device that is associated with said user. The OS platform-level gaming module may be operable to copy corresponding configurations and settings for the game installed on the first wired and/or wireless communication device to the cloud.
US09981189B1 System and method for predicting in-game activity at account creation
This disclosure relates to a system and methodology for dynamically adjusting a game based on predictions made during game account creation in accordance with one or more implementations. The system may be configured to receive user information included in platform level accounts which were previously created by users on an online platform and assign one or more user types to the user based on that user information. The system may be configured such that game adjustments associated with one or more user types for future play by users associated with that user type may be modified over time based on historical and ongoing game activities undertaken by users associated with one or more user types.
US09981185B2 Server enabled user data exchange between information processing devices
A server device includes: a receiving unit configured to receive, from each of a plurality of information-processing devices, location information showing a respective location of each information-processing device; a setting unit configured to set a condition showing that one information-processing device is close to another information-processing device, based on a predetermined parameter; a determining unit configured to determine whether a first information-processing device and a second information-processing device from among the plurality of information-processing devices satisfy the condition based on the location information received by the receiving unit; and a transmitting unit configured to transmit information determined at the determining unit to the first information-processing device and the second information-processing device, in a case that the determining unit determines that the first information-processing device and the second information-processing device satisfy the condition.
US09981183B2 Haptic peripheral having a haptically-enhanced user input element including a mechanical key and an integrated smart material actuator for providing haptic effects
A haptic peripheral includes a housing and a haptically-enhanced user input element. The haptically-enhanced user input element is configured to receive an input from a user, and includes a mechanical key having a keycap with a user contact surface configured to contact the user and a smart material actuator integrated onto the user contact surface of the keycap. The smart material actuator is configured to receive a control signal from a processor and is configured to deform at least a portion of the user contact surface relative to the keycap of the mechanical key in response to the control signal from the processor to thereby provide a haptic effect to a user of the haptic peripheral. The haptic peripheral may also include a braking actuator coupled to the mechanical key to hold the mechanical key in a depressed position to indicate an inactive status to a user. In addition, the haptic peripheral and the haptically-enhanced user input element may be modular.
US09981180B2 Die rolling and identification apparatus and gaming machine
A die rolling and identification apparatus having a die container with a die shaker, an opening connector and a die slide and containing a least one die, the opening connector is between the die shaker and the die slide to enable the die to move between the die shaker and the die slide through the opening connector; a motor and a plurality of gears connected to the motor. The plurality of gears turn the die container, the die slide has a slide lower surface and slide upper surface, the slide lower surface and the slide upper surface are substantially parallel such that the die slides in the die slide without rolling, the die shaken in the die shaker are stopped in a prescribed position in the die slide and the die are read by light sensors disposed on a surface of the die slide.
US09981177B2 Apparatus for use with a protective cup
An apparatus for use with a protective cup is disclosed. The apparatus includes a plurality of support members which may position the protective cup in a preferred position relative to a user's body, and secure the protective cup in the preferred position. The plurality of support members may connect to the protective cup or a protective support configured to receive the protective cup. The apparatus may be configured to protect the user's groin region, such as the user's crotch area, pubic bone and genitals. The apparatus may also be configured to protect the user's buttocks or legs, such as the user's hips, thighs, shins or knees.
US09981176B2 Sport racket vibration dampener and score keeping device and methods of use
An apparatus to keep score during a tennis or other racket match being affixed to a set of racket strings, the apparatus includes a housing having a perimeter, a front surface and a rear surface, each surface configured with indicia to indicate game and set score, said perimeter includes a groove therearound to removeably affix housing to the racket strings, wherein the housing includes a pair of stacked polygon apertures, the front polygon being a hexagon and the second being a pentagon, and a pair of stacked pluggable dials, the front polygon being a hexagon and the second being a pentagon, wherein said pluggable dials include a finger grip, indicator, base or stop, and annular male female snap, and thus to facilitate keeping game and set score during a match and to provide vibrational dampening.
US09981175B2 Taekwondo bag
The present invention provides for a taekwondo bag comprising: a housing comprising a main compartment and a front panels that closes and opens to access the main compartment, and the main compartment comprising top and bottom portions; and at least one helmet carrier designed to receive an Olympic taekwondo helmet, and the helmet carrier is situated within the main compartment of the housing of the bag.
US09981174B1 Front toss machine
Systems and methods of ball tossing machines. Ball tossing machines having reconfigurable joints are contemplated. Embodiments having dynamically articulating joints create tossing arms that mimic human arms completing underhanded tosses. In other embodiments, the tossing arm's elbow and fingers can be locked into place and pivoted about a shoulder to accomplish a basic tossing motion with an altered effective tossing arm length.
US09981172B2 Athletic coaching system and method
An athletic coaching method and jersey system are provided. The method utilizes jerseys with securing elements attached thereto. Number panels having specific player numbers are secured to the jerseys for use during practice. Scout team players wear the jerseys during practice. Each scout team player has a different number to represent the jersey number of a player on an opposing team in an upcoming game. The method allows coaches to more realistically simulate a game against an opposing team in practice. When the opposing team changes for the next game, each scout team player can continue to wear the same jersey but change the jersey number by switching number panels to represent a different player on the team of the next opponent. Thus, jersey numbers can be changed so that a game can be simulated for any opponent.
US09981169B2 Golf club head or other ball striking device with removable and/or movable sole member
A ball striking device, such as a golf club, includes a head with a face having a striking surface configured for striking a ball and being defined by a plurality of peripheral edges, a body connected to the face and extending rearwardly from the peripheral edges of the face, and a sole member connected to the sole of the body. The sole member may be removably connected to the sole, which can permit removal and replacement with another sole member having a different property. The sole member may additionally or alternately be movably connected to the sole, which can permit adjustment of the sole member, such as to change the lie angle of the head. The sole member may be at least partially received in a receiver in the sole and may form at least a portion of the lowermost surface of the head.
US09981166B2 Golf club head
A wood-type golf club head includes a main body and a striking wall associated with the main body. The striking wall has a striking face including a face center, a first imaginary plane tangent to the face center, and a rear surface opposite the striking face. In a second imaginary plane perpendicular to the first imaginary plane and passing through the face center, the striking face includes a first point associated with a maximum thickness, tmax, of the striking wall, and a second point associated with a minimum thickness, tmin, of the striking wall, such that a ratio, tmax/tmin, is no less than 1.70. Also, in the second imaginary plane, the striking wall gradually tapers in thickness entirely from the first point to the second point.
US09981165B2 CG height adjustability by conformal weighting
A golf club head comprising a conformal weight sized to fit within a recess or channel disposed in a crown or sole is disclosed herein. In some embodiments, the crown or sole itself is a conformal weight, and is removably affixed to a base structure comprising a striking face and a skeletal support structure. In other embodiments, the golf club head comprises a conformal weight in the form of a sole cap that is removably affixed to the golf club head and covers small weight ports disposed in the sole.
US09981164B2 Golf club head and manufacturing method for same
The present invention provides a golf club head that enables increasing the moment of inertia while also improving durability, and a manufacturing method for the same. The golf club head of the present invention includes a crown portion. The crown portion has a first region having a first thickness and multiple second regions having a second thickness that is smaller than the first thickness. The second regions are distributed in a radiating fashion so as to extend from an origin toward a peripheral portion of the crown portion excluding the face side, the origin being located within 15 mm of the center of gravity of the golf club head in the toe-heel direction and also being located in the vicinity of the face side in the face-back direction in a plan view.
US09981153B2 Brake controller for spinner bike
A brake controller for spinner bikes has a frame body engaging a pair of connecting pieces, a shaft engaging a first block through a top end thereof and a second block through a bottom end thereof, and a magnetic encoder that has a PCB with coding circuit for detecting rotation of a magnet disposed under the second block. Thereby the brake controller controls two kinds of braking forces by a single button for spinner bikes.
US09981152B2 Evacuation device
An evacuation device (1) for transporting gas and/or particles out of a room includes mounting elements (7, 9) for installation in a wall (3) of the room such that an inflow end (6) is located on the face of the wall (3) that faces the inside of the room and an outflow end (8) is located outside the room. The evacuation device includes a duct (2) extending between the inflow end and the outflow end, and a barrier (12) is releasably attached in the duct to seal it when the evacuation device is in a standby state. Driving elements (21) are arranged to guide at least one flow of fluid through the duct when the evacuation device is in an activated state. Preferably, the duct includes a venturi nozzle, and the driving elements include a number of water nozzles located upstream of the inflow end of the venturi nozzle.
US09981151B2 Power and data port interface for electronic devices operating in extreme environments
This invention is embodied in a power/data interface for connecting two modules at the leading edge (i.e., the “tip of the spear”) of a fire suppression operation. The power/data interface serves as an operational link between a housing device (for protecting a battery and other electronic equipment) and an accessory like a thermal imaging camera (“tic” camera), video camera or other sensory perceiving device. The power/data interface not only provides power to an accessory by connecting it to a power source, but the power/data interface can exchange data between the accessory and the housing device. Such exchange of data enables electronics stored within the housing device to record and protect data captured by accessory on a flash drive or other recordable media. In addition to providing power and exchanging data with an accessory, the power/data interface can also accept battery pack that can be used to recharge a battery or other power source located inside the housing device.
US09981144B2 System and method for scanned ion beam interplay effect mitigation using random repainting
Interference of dose application in scanned ion beam therapy and organ motion, also called interplay effect, may lead to dose deviations at target volumes. Current repainting methods are susceptible to artifacts due to a predominant scanning direction, ranging from fringed field edges to under and overdosed regions (hot and cold spots). To overcome the difficulties inherent in the repainting techniques of conventional proton therapy systems, new random repainting techniques are described herein for mitigating the under-dose and/or over-dose pattern inherent in existing repainting techniques using a random repainting approach that randomly selects spot locations within the target area.
US09981141B2 Intelligent sync mode for defibrillation
The defibrillator may include a heart rhythm detector to detect the heart rhythm of a patient, a manual mode controller structured to set the defibrillator in a synchronous shock operating mode or an asynchronous shock operating mode depending on an input from a human operator, a shock module to cause the defibrillator to deliver a shock to the patient according to the operating mode, and an automatic mode controller structured to, after the shock module has delivered the shock to the patient, set the external defibrillator to the synchronous shock operating mode or the asynchronous shock operating mode depending on the detected heart rhythm of the patient and without input from the human operator.
US09981137B2 Heat dispersion for implantable medical devices
An implantable medical device that includes electrical circuitry for providing a therapy to a patient. The device also includes a housing forming an inner chamber that is adapted for receiving, at least a portion of the electrical circuitry. The device further includes a thermally conductive material that is configured to disperse heat from a first portion of the implantable medical device that is located in proximity to a heat generating component of the electrical circuitry, to a second portion of the implantable medical device that is not located in proximity to said heat generating component. The thermally conductive material is a discrete component separate from the electrical circuitry and the housing.
US09981134B2 Multi-channel neuromodulation system having frequency modulation stimulation
A neuromodulation system comprises a plurality of electrical terminals configured for being respectively coupled to electrodes, modulation output circuitry configured for respectively outputting a plurality of individual electrical pulse trains in a plurality of timing channels to the electrical terminals, wherein each of the timing channels prevents the respective pulse train from having a specific characteristic, and control circuitry configured for controlling the modulation output circuitry in a manner that outputs the pulse trains to a common set of the electrical terminals, thereby creating a combined electrical pulse train at the common set of electrical terminals that has the specific characteristic. A method of providing therapy to a patient comprises delivering a plurality of electrical pulse trains respectively in a plurality of timing channels to a common set of electrodes implanted within the patient, thereby creating a combined electrical pulse train at the common set of electrical terminals.
US09981131B2 Systems and methods for determining spinal cord stimulation parameters based on patient feedback
The present disclosure provides a grip sensor for quantifying pain experienced by a patient during spinal cord stimulation (SCS). The grip sensor includes an electronics enclosure, an annular outer shell substantially surrounding the electronics enclosure and sized to be held by the patient, a pressure sensor embedded in the outer shell and communicatively coupled to the electronics enclosure, the pressure sensor configured to measure a grip strength of the patient as SCS is applied to the patient, and a plurality of galvanic skin response sensors communicatively coupled to the electronics enclosure and configured to measure an electrical impedance of the skin of the patient as SCS is applied to the patient.
US09981129B2 Universal implant
A universal implant for an implantable medical device, the universal implant including a plurality of functional components, having a plurality of hardware components disposed in a housing, and an auxiliary component interface disposed in a surface of the housing and configured to electrically connect any one of a plurality of auxiliary components to said hardware components. The universal implant further includes a determinator configured to identify one or more of the auxiliary components, select one or more of said functional components based on the identified auxiliary components, and adapt said selected functional components for operation with the identified auxiliary components.
US09981126B1 System and method for controlling the surface charge of a region of tissue
A system and method for preventing the undesirable dissipation of charge throughout a tissue surface while maintaining the charge density at a desired tissue treatment site. The invention embodies a physical perimeter conductor positioned in proximity to a tissue surface and a conductance control circuit working in combination to collect surface charge applied within the confines of the perimeter conductor and to maintain a desired relationship between the contained surface charge density and time.
US09981124B2 Devices and techniques for detecting magnetic resonance imaging field
A device includes a housing configured to be implanted in a patient. The device also includes a first magnetic field direction sensor located at a first location within the housing and configured to generate a signal representative of a first direction of a magnetic field at the first location, a second magnetic field direction sensor located at a second location within the housing and configured to generate a signal representative of a second direction of the magnetic field at the second location, and a magnetic field strength sensor configured to generate a signal representative of a strength of the magnetic field. The device further includes a control module configured to identify a source of the magnetic field based on at least one of the signal representative of the strength of the magnetic field and the signals representative of the first and second directions of the magnetic field.
US09981120B2 Electrode set and stimulating device
The electrode set for a stimulation device, such as a TENS or EMS stimulation device comprises at least a plurality of neighboring electrically active zones close to each other said active zones forming a succession of poles of alternating polarity or being grouped to form groups of poles of alternating polarity, wherein at least one of said active zone or group of zones has a lateral size (D2) of approximately 1 mm to 40 mm, wherein at least one of spacing (D1) between neighboring active zones or groups of zones is approximately of 1 mm to 40 mm, and said set further comprises contacting means connected to said active zones or groups of active zones.
US09981117B2 Implantable infusion devices and associated methods
Implantable infusion devices configured to improve fill and evacuation procedures.
US09981116B1 Computerized oral prescription administration devices and associated systems and methods
Computerized oral prescription administration (COPA) devices, systems, and methods are provided. In one embodiment, a substance dispensing apparatus, comprising a mouthpiece having a recess customized to match with an intended user's unique dentition; a user verification mechanism configured to determine whether the intended user's unique dentition is positioned within the recess; and an actuator coupled to the mouthpiece and in communication with the user verification mechanism, the actuator configured to dispense a substance from a reservoir coupled to the mouthpiece in response to the user verification mechanism determining that the intended user's unique dentition is positioned within the recess.
US09981114B2 Winged injection needle
A winged injection needle including an injection needle main body, a base that supports the base end of the injection needle main body and wings that protrude from the base toward the left and right sides to function as handles, the wings being constructed with plate members that are freely foldable through hinge sections so that in the folded state, they protrude from the base toward the left and right sides to function as handles, while in the expanded state, they extend from the base along the injection needle main body toward the leading edge of the injection needle to function as a safety cover that covers the injection needle main body.
US09981108B2 Method and apparatus for treatment of hypertension through percutaneous ultrasound renal denervation
Apparatus and methods for deactivating renal nerves extending along a renal artery of a mammalian subject to treat hypertension and related conditions. An ultrasonic transducer (30) is inserted into the renal artery (10) as, for example, by advancing the distal end of a catheter (18) bearing the transducer into the renal artery. The ultrasonic transducer emits unfocused ultrasound so as to heat tissues throughout a relatively large impact volume (11) as, for example, at least about 0.5 cm3 encompassing the renal artery to a temperature sufficient to inactivate nerve conduction but insufficient to cause rapid ablation or necrosis of the tissues. The treatment can be performed without locating or focusing on individual renal nerves.
US09981107B2 Methods and systems for gathering and analyzing human biological signals
Introduced are methods and systems for: gathering human biological signals, such as heart rate, breathing rate, or temperature; analyzing the gathered human biological signals; and controlling home appliances based on the analysis.
US09981106B2 Oscillating positive expiratory pressure device
A respiratory treatment device comprising at least one chamber, a chamber inlet configured to receive exhaled air into the at least one chamber, at least one chamber outlet configured to permit exhaled air to exit the at least one chamber, and an exhalation flow path defined between the chamber inlet and the at least one chamber outlet. A restrictor member positioned in the exhalation flow path is moveable between a closed position, where a flow of exhaled air along the exhalation flow path is restricted, and an open position, where the flow of exhaled air along the exhalation flow path is less restricted. A vane in fluid communication with the exhalation flow path is operatively connected to the restrictor member and is configured to reciprocate between a first position and a second position in response to the flow of exhaled air along the exhalation flow path.
US09981100B2 Tracheostomy valves and related methods
The embodiments of the present tracheostomy valves include a flexible diaphragm abutting a rib shaped substantially as a flat plate. Opposite the rib, the diaphragm abuts a boss and forms an uninterrupted seal therewith. As the tracheostomized patient inhales, the diaphragm bends about the rib, interrupting the seal and allowing air to flow smoothly into the valve. The features of the various embodiments contribute to a positive seal at all times except during inhalation, and low resistance to airflow through the valve during inhalation.
US09981098B2 Apparatus for assisted ventilation and corresponding regulation method
An apparatus, for assisted ventilation (1), includes at least one ventilatory device (2) connected to and controlled by a driver (3), and at least one sensor device (4) connected to the driver (3) and adapted to provide it with a signal of electrical activity produced by the diaphragm. The apparatus further includes at least one calculation device (5) connected to the driver (3), to the sensor device (4) and to the ventilatory device (2), the calculation device (5) receiving from the sensor device (4) a signal of diaphragmatic activity (Eadi) and from the ventilatory device (2) a ventilatory pressure signal (Paw) and providing the driver (3) with calibration parameters (Cal) calculated on the basis of a signal of diaphragmatic electrical activity (Eadi*) and a ventilatory pressure signal (Paw*) upon switching-off said ventilatory device (2) so as to cause an expiratory pause.
US09981097B2 Systems and methods for compensating long term sensitivity drift of electrochemical gas sensors exposed to nitric oxide
Described are systems and methods for compensating long term sensitivity drift of catalytic type electrochemical gas sensors used in systems for delivering therapeutic nitric oxide (NO) gas to a patient by compensating for drift that may be specific to the sensors atypical use in systems for delivering therapeutic nitric oxide gas to a patient. The long term sensitivity drift of catalytic type electrochemical gas sensors may be addressed using calibration schedules, which can factor in the absolute change in set dose of NO being delivered to the patient that can drive one or more baseline calibrations. The calibration schedules can be used to reduce the amount of times the sensor goes offline.
US09981095B2 Process for operating a respirator or anesthesia device in the APRV mode taking into the impedance and/or the impedance change
A process is provided for operating a respirator and/or anesthesia device in the APRV mode with at least one pressure release phase with the step of setting a first point in time for terminating the pressure release phase. The process includes measuring the electrical impedance and/or impedance change of the lungs and setting the first point in time such that the measured impedance and/or impedance change are taken into account. A device is provided for carrying out the process according to the present invention.
US09981091B2 Dry powder inhalator
A dry powder inhaler including a main body, a plurality of individual reservoirs, such as blisters, each containing a single dose of powder, and disposed one behind another on a flexible strip, and an opening mechanism provided for opening an individual reservoir each time the device is actuated. The device includes first a displacement mechanism adapted to displace an individual reservoir to face the opening mechanism before and/or after each actuation, and a second displacement mechanism adapted to displace an individual reservoir against the opening mechanism on each actuation. The first displacement mechanism having an indexer wheel provided with a recess that receives an individual reservoir, the recess defined by a bottom wall and an inner side wall of said indexer wheel, and by an outer side wall formed on a separate adjustment element assembled on the indexer wheel.
US09981087B2 Automatic injection device
Automatic injection device includes a housing, a syringe, a plunger, and a syringe carrier. The housing includes a barrel. The barrel includes an elongated window to allow viewing of contents inside the housing. The syringe is disposed within the housing and has a reservoir. The plunger is at least partially disposed within the syringe and includes a visual indicator. The syringe carrier is disposed within the housing and configured to contain the syringe and displace the syringe within the housing between a first position and a second position. The syringe carrier can have at least one opening and at least one pair of legs defining at least a portion of the at least one opening.
US09981086B2 Automatic injection device
An automatic injection device for delivering a dose from a medicine containing syringe includes a housing for containing the syringe, a force applicator for applying a force to eject medicine from the syringe, a trigger coupled to the force applicator for releasing the force applicator to cause an injection, a boot covering a needle attached to the syringe to protect and maintain sterility of the needle, and a mechanical interlock. The mechanical interlock prevents actuation of the trigger prior to removal of the boot. When the boot is removed, the mechanical interlock allows for actuation of the trigger.
US09981084B2 Integrated spring-activated ballistic insertion for drug delivery
An infusion set has an integrated ballistic inserter that can insert a needle at a controlled high rate of speed to a depth to deliver content to the upper 3 mm of skin surface, and a skin securing, adhesive layer to secure the skin surface at the insertion site such that the inserter that can insert a needle without a risk of tenting of the skin surface. A driving spring of the ballistic inserter is captured within the ballistic inserter, and can be released by user operation, to insert a needle at such a controlled rate of speed.
US09981077B2 Ventricular cuff
In one general aspect, a cuff for attachment to a heart includes an attachment component configured to engage a blood pump to attach the cuff to the blood pump and a sewing ring for attachment to the heart. The sewing ring is coupled to the attachment component, and the attachment component and the sewing ring each define a central opening configured to admit an inflow cannula of a blood pump. The sewing ring comprises a member that provides rigidity to flatten a portion of a myocardium of the heart when the cuff is attached to the heart.
US09981076B2 Ventricular cuff
In one general aspect, a cuff for attachment to a heart includes an attachment component configured to engage a blood pump to attach the cuff to the blood pump and a sewing ring for attachment to the heart. The sewing ring is coupled to the attachment component, and the attachment component and the sewing ring each define a central opening configured to admit an inflow cannula of a blood pump. The sewing ring comprises a member that provides rigidity to flatten a portion of a myocardium of the heart when the cuff is attached to the heart.
US09981068B2 Polymers which resist bacterial attachment
The invention provides a method for inhibiting bacterial attachment to a surface, the method comprising forming the surface from a polymer, or applying a polymer to the surface, wherein the polymer is a homopolymer formed from a (meth) acrylate or (meth) acrylamide monomer or a copolymer formed from one or more (meth) acrylate or (meth) acrylamide monomers, wherein the (meth) acrylate or (meth) acrylamide monomers are of formula (I) or (II): [H2C═CR′—C(═O)—O—]nR  (I) [H2C═CR′—C(═O)—NH—]nR  (II) wherein n is 1, 2 or 3, R′ is independently H or CH3, R is an organic group having a total of from 2 to 24 carbon atoms, wherein the organic group includes an aliphatic or aromatic hydrocarbon moiety and wherein the organic group does not include any hydroxyl groups.
US09981066B2 Anti-thrombogenic grafts
The present invention provides anti-thrombogenic compositions, including anti-thrombogenic vascular grafts. In certain embodiments, the compositions comprise decellularized tissue coated with an anti-thrombogenic coating. The present invention also provides methods of preparing anti-thrombogenic compositions and methods of treatment comprising implanting the anti-thrombogenic compositions into a subject in need thereof.
US09981063B2 Biosynthetic composite for osteochondral defect repair
A composite for osteochondral defect repair includes a porous scaffold and a periosteal graft secured to a surface of the scaffold. The composite provides cartilage growth from autologous periosteum chondrogenesis. Biological resurfacing of large osteochondral defects, or a complete joint is feasible using the porous scaffold/autologous periosteal composite. The use of this composite eliminates the necessity of using normal cartilage surface as a donor site and its respective associated morbidity. In one form, the strong bone integration capacity of a porous metal (e.g., tantalum) scaffold and the high grade of integration observed from periosteal chondrogenesis into the normal cartilage eliminates the lack of chondral-chondral integration observed in the autologous osteochondral graft technique.
US09981059B2 Sugar chain-polypeptide complex
The object of the present invention is to provide a sugar chain-polypeptide complex that may form a transparent and homogeneous hydrogel in a broad pH. The present invention provides a sugar chain-polypeptide complex, characterized in that said polypeptide is a polypeptide comprising an amino acid sequence consisting of 8-34 amino acid residues in which polar and nonpolar amino acid residues are alternately arranged, and one or more sugar chains are bound to said polypeptide.
US09981057B2 Sheet-like carbon nanotube-polymer composite material
Use of a sheet-like composite material for the manufacture of an immobilization element, wherein the sheet-like composite material is made from a material comprising a thermoplastic polymer containing carbon nanotubes as a fibrous reinforcing material, obtainable by dispersing carbon nanotubes in a dispersing liquid in which the thermoplastic polymer does not dissolve, subjecting the dispersion to an ultrasonic treatment, adding of particles thermoplastic polymer to the dispersion and mixing of the thermoplastic polymer with the dispersion of carbon nanotubes, removing of the dispersing liquid, forming of the thermoplastic polymer impregnated with carbon nanotubes into a sheet.
US09981054B2 Circuit loops to control fluids
Discussed herein are systems, apparatuses, and methods for reversing a flow through a conduit loop. A system may include a flow reversing loop having an inlet, an outlet in communication with a drain, a first port on a first side of the flow reversing loop, and a second port on a second side of the flow reversing loop, the first and second sides separated by the inlet and outlet, a conduit loop including one or more flow paths, wherein the flow reversing loop includes a first flow path from the inlet to the first port so that the treatment fluid can flow through the conduit loop in a first direction to the outlet of the flow reversing loop, and a second flow path from the inlet to the second port so that the treatment fluid can flow to the drain in a second direction, opposite of the first direction.
US09981051B2 Ultraviolet gradient sterilization, disinfection, and storage system
Systems and methods for disinfecting a storage area and/or items within a storage area can include at least one ultraviolet radiation source configured to generate ultraviolet radiation directed within a storage area and a monitoring and control system. The monitoring and control system can be configured to monitor at least one of the storage area or a set of items located in the storage area and control ultraviolet radiation generated by the at least one ultraviolet radiation source based on the monitoring by delivering targeted ultraviolet radiation to at least one designated zone within the storage area.
US09981050B2 Bispecific peptide conjugate and radioactive bispecific peptide imaging agent
Disclosed herein is a bispecific peptide conjugate comprising an epidermal growth factor receptor (EGFR) targeting peptide, an αvβ3 integrin targeting peptide, and a linker, where the linker is conjugated respectively to the EGFR targeting peptide and the αvβ3 integrin targeting peptide.
US09981046B2 Drug-conjugates, conjugation methods, and uses thereof
In one aspect, an active agent-conjugate, methods of preparing the active agent-conjugate, and uses thereof is provided.
US09981040B2 Capsule formulation
An object of the present invention is to provide a capsule formulation comprising a phosphonooxymethyl derivative of ravuconazole which suppresses delay in dissolution due to storage regardless of an encapsulated amount of the phosphonooxymethyl derivative of ravuconazole. The present invention provides a capsule formulation comprising an encapsulated material comprising {[(1R,2R)-2-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-1-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-ylmethyl)propyl]oxy}methyl dihydrogen phosphate or a pharmacologically acceptable salt thereof, or a solvate of any of the foregoing, and a capsule shell not comprising gelatin.
US09981031B2 Injectable vaccines against multiple meningococcal serogroups
An injectable immunogenic composition comprising capsular saccharides from at least two of serogroups A, C, W135 and Y of Neisseria meningitidis, wherein said capsular saccharides are conjugated to carrier protein(s) and/or are oligosaccharides, and wherein (i) the composition comprises <50 μg meningococcal saccharide per dose, and/or (ii) the composition further comprises an antigen from one or more of (a) serogroup B N. meningitidis; (b) Haemophilus influenzae type B; and/or (c) Streptococcus pneumoniae. Saccharide antigens in the compositions are generally conjugated to a carrier.
US09981028B2 Polypeptides and immunizing compositions containing gram positive polypeptides and methods of use
The present invention provides isolated polypeptides isolatable from a Staphylococcus spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.
US09981027B2 Vaccine against colibacillosis
The present invention provides an agent for controlling colibacillosis including a fusion protein comprising a subunit of Shiga toxin and a subunit of Escherichia coli heat-labile toxin.
US09981023B2 Compositions and methods for inducing immune tolerance
The present invention provides liposomal compositions for inducing immune tolerance. The compounds typically comprise a liposome displaying a specific antigen and also a binding moiety for a sialic acid binding Ig-like lectin (Siglec) expressed on B cells. The invention also provides methods for inducing tolerance to a protein or polypeptide antigen (e.g., a protein antigen) in a subject. The methods involve administering to the subject a pharmaceutical composition thatco-presents both the antigen and a glycan ligand for a Siglec expressed on B lymphocytes.
US09981020B2 Methods and compositions for RNA-guided treatment of HIV infection
A method of inactivating a proviral DNA integrated into the genome of a host cell latently infected with a retrovirus by treating the host cell with a composition comprising a Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated endonuclease, and two or more different guide RNAs (gRNAs), wherein each of the at least two gRNAs is complementary to a different target nucleic acid sequence in a long terminal repeat (LTR) in the proviral DNA, and inactivating the proviral DNA. A composition for use in inactivating a proviral DNA integrated into the genome of a host cell latently infected with a retrovirus including isolated nucleic acid sequences comprising a CRISPR-associated endonuclease and a guide RNA, wherein the guide RNA is complementary to a target sequence in a human immunodeficiency virus.
US09981019B2 Methods and materials for reducing the severity of viral infections
This document relates to methods and materials involved in treating and/or preventing and/or reducing the severity of a viral infection present in a mammal. For example, methods and materials for reducing the severity of a viral infection present in a mammal (e.g., a human) are provided.
US09981018B2 Compositions and methods for modulating toll-like receptor 2 activation
A method of promoting hair growth of a subject includes administering to follicle cells of the subject a therapeutically effective amount of a TLR2 agonist that promotes TLR2 activation and hair growth of the subject.
US09981016B2 Treatment of short bowel syndrome patients with colon-in-continuity
Intestinal absorption is enhanced in short bowel syndrome patients presenting with colon-in-continuity by treatment with a GLP-2 receptor agonist, such as teduglutide.
US09981011B2 Methods of promotion of healing of diabetic wounds
A method of treating a wound in a diabetic patient is provided. The method includes administering a therapeutically effective amount of Chemokine (C-C motif) ligand 2 (CCL2) to a wound site. In another aspect, a method of treating a wound in a diabetic patient is provided. The method includes assaying a level of CCL2 in the diabetic patient relative to a level of CCL2 in a normal subject and administering a therapeutically effective amount of CCL2 to the diabetic patient.
US09981007B2 Drug containing recombinant mistletoe lectins for treating malignant melanoma
A drug and/or pharmaceutical composition comprising recombinant mistletoe lectins for treating metastatic tumors, including malignant melanoma such as stage IV malignant melanoma, and use of said drug, particularly in select patient populations, are described. Recombinant mistletoe lectin polypeptides can be a mistletoe lectin A-chain or fragments thereof. Alternatively, the recombinant mistletoe lectin polypeptides can be mistletoe lectin B-chain or fragments thereof. The drug can be used for the treatment of stages III and IV of a metastatic tumor or skin cancer, as well as to treat non-responders and therapeutic failures of a standard tumor therapy. The drug can be used in a dosage in a range of 3-7 ng recombinant mistletoe lectin per kg body weight. The dosage of the recombinant mistletoe lectin can also be 200-500 ng, independently of body weight. The drug can be administered once a week, or more frequently.
US09981000B2 Composition for treating diabetes and dyslipidemia obtained from the extract of Costus pictus D. don plant and a method of preparing the same
The disclosure provides a medicinal composition for treating diabetes and dyslipidemia obtained from the extract of Costus pictus D. Don. The extract of Costus pictus D. Don includes hydroxycinnamic acid derivatives and flavonol mono-, di- and triglycosides along with small amounts of free flavonols. The extract of Costus pictus D. Don has low levels of oxalic acid and/or oxalates. The hydroxycinnamic acid derivatives include caffeic acid, p-coumaric acid, ferulic acid and sinapic acid and flavonol mono-, di- and triglycosides which include quercetin, kaempferol and isorhamnetin with sugars glucose, galactose and rhamnose. Disclosure also provides a method of preparing the extract of Costus pictus D. Don of the same. The disclosure also provides a method of treating mammals including human beings for medical conditions such as diabetes; dyslipidemia and related conditions; for increasing anti oxidant potential; for the regeneration of pancreatic beta cells and increasing the insulin secretogogue effect.
US09980999B2 Method for producing dry extracts
The invention relates to a method for producing dry extracts of plants and to pharmaceutical preparations containing the same, more particularly phytopharmaceuticals, which contain at least one ethanolic/aqueous extract of a plant (drug), the plants being selected from the group consisting of: Rumicis herba; Verbena officinalis; Sambucus nigra; Primula veris; and Gentiana lutea and mixtures thereof. The invention further relates to a pharmaceutical for treating inflammatory and/or infectious diseases of the nose and throat area and/or the nasal sinuses, as well as the use thereof.
US09980995B2 Method for reducing total gas production and/or methane production in a ruminant animal
The present invention relates to a method of reducing total gas production and/or methane production in a ruminant animal.
US09980994B2 Myxoma virus mutants for cancer treatment
Myxoma viruses that are deficient in the activity of a Myxoma virus protein selected from the group consisting of M11L, M063, M 136, M-T4 and M-T7 are useful for treating cancer.
US09980992B2 Lactobacillus with decreased lipoteichoic acid to reduce inflammatory responses
Methods and compositions for treating or preventing inflammatory disorders are provided. The compositions of the invention comprise a recombinant bacterium genetically modified to decrease the display of lipoteichoic acid on the cell surface. Methods of the invention comprise administering to a subject a recombinant bacterium modified to decrease the display of lipoteichoic acid on the cell surface. Administration of the recombinant bacterium promotes a desired therapeutic response. The recombinant bacterium may be administered in a single dose or series of doses. Methods of the invention find use in treating or preventing a variety of inflammatory disorders including, for example, treating or preventing inflammatory bowel disease, colitis, or Crohn's disease.
US09980987B2 Treatment of diseases and conditions caused by increased vascular permeability
The invention is directed to methods for the treatment of diseases and conditions caused by increased vascular permeability. The invention is also directed to methods for returning vascular permeability that is a symptom of a disease or condition to a homeostatic state. Specifically, the invention is directed to methods for the treatment of diseases and conditions caused by increased vascular permeability or returning vascular permeability that is a symptom of a disease or condition to a homeostatic state by administering to a subject suffering from such diseases and conditions and symptoms novel cellular factor-containing solution compositions (referred to herein as “CFS” compositions), including novel sustained-release cellular factor-containing solution compositions (referred to herein as “SR-CFS” compositions).
US09980985B2 Pharmaceutical coposition of cardiac stem cells and mesenchymal stem cells
Compositions comprising stem cells delivered into infarcted myocardium by endocardial injection, engraft and differentiate into myocytes, endothelial cells, and vascular smooth muscle, and do so without the requirement for survival enhancing modification. These cells engraft whether injected acutely (days) or late (months) after myocardial infarction, and the efficiency of engraftment correlates with the functional recovery of the heart. The stem cells also recruit endogenous cardiac precursor cells, reconstitute myocardial stem cell niches, and enhance endogenous cell differentiation into myocytes.
US09980980B2 Compounds, compositions and methods for protecting brain health in neurodegenerative disorders
Aspects of the invention relate to compounds, extracts and compositions thereof, and methods of using of the same, to treat neurodegenerative disorders and/or improve brain health. In certain embodiments, said compounds are pomegranate flavonoids.
US09980973B2 Bicyclic heterocycle compounds and their uses in therapy
The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising the compounds and to the use of the compounds in the treatment of diseases, e.g. cancer.
US09980970B2 Use of PAR-1 antagonists for preventing and/or treating pelvi-perineal functional pathological conditions
The present invention relates to the use of PAR1 antagonists, in particular of vorapaxar, of atopaxar and of 3-(2-chlorophenyl)-1-[4-(4-fluorobenzyl)piperazin-1-yl]propenone, or a pharmaceutically acceptable salt thereof, for preventing and/or treating pelvi-perineal functional pathological conditions, and more particularly painful bladder syndrome.
US09980967B1 Method for overcoming drug resistance of EGFR mutation and cancerous stemness of human non-small cell lung carcinoma
EGFR mutation (T790M) and cancerous stemness have shown drug resistances in human non-small-cell lung cancer (NSCLC), thus development of novel drugs in overcoming drug resistances in the NSCLC therapy is highly desired. SP101 is a novel gefitinib derivative, which can bind the ATP-binding pocket of EGFR to inhibit its EGFR kinase activity. SP101 can reduce the drug resistances of EGFR mutation (T790M) and cancerous stemness in NSCLC. SP101 induced cancer cell death and apoptosis in the gefitinib-resistant EGFR mutation (T790M) H1975 cells. SP101 inhibited phosphorylated EGFR and its downstream Survivin proteins but conversely induced Caspase 3 activation for apoptosis induction. Moreover, SP101 could decrease Oct4 protein level and reduce Survivin proteins but conversely elicited active Caspase 3 in the xenograft human H1975 lung tumors in nude mice.
US09980966B2 Combinations of cancer therapeutics
The invention relates to combinations of 4-[(S)-2-Azetidin-1-yl-1-(4-chloro-3-trifluoromethyl-phenyl)-ethylamino]-quinazoline-8-carboxylic acid amide and/or its physiologically acceptable salts and solvates, and an inhibitor of Her2, and the use of such combinations for the treatment of cancer.
US09980965B2 Treatment of autoimmune disease
Provided herein are compositions and methods for the treatment of autoimmune diseases, including lupus, uveitis and encephalitis. Said compositions useful for treating autoimmune diseases comprise pyrrolo-pyrazole PKC inhibitors.
US09980961B2 Pyruvate kinase activators for use in therapy
Described herein are methods for using compounds that activate pyruvate kinase.
US09980960B2 Methods for determining the risk of cardiovascular disease in a subject having a chronic viral infection
A method for determining the risk of cardiovascular disease in a subject having a chronic viral infection includes determining a level of ectonucleotide pyrophosphatase/phosphodiesterase-2 (ENPP2) in the subject and comparing the determined level of ENPP2 to a control level, wherein an increased level of ENPP2 is indicative of the subject having an increased risk of cardiovascular disease associated with the chronic viral infection.
US09980952B2 Modulators of methyl modifying enzymes, compositions and uses thereof
Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.
US09980951B2 Image guided therapy for cancer
The invention provides a method to treat cancer in an animal comprising administering a tetra-arylethylene cation to the animal.
US09980949B2 SNS-595 and methods of using the same
The present invention relates to SNS-595 and methods of treating cancer using the same.
US09980943B2 Methods of treating muscular dystrophy
Disclosed herein are α7β1 integrin modulatory agents and methods of using such to treat conditions associated with decreased α7β1 integrin expression or activity, including muscular dystrophy. In one example, methods for treating a subject with muscular dystrophy are disclosed. The methods include administering an effective amount of an α7β1 integrin modulatory agent to the subject with muscular dystrophy, wherein the α7β1 integrin modulatory agent increases α7β1 integrin expression or activity as compared to α7β1 integrin expression or activity prior to treatment, thereby treating the subject with muscular dystrophy. Also disclosed are methods of enhancing muscle regeneration, repair, or maintenance in a subject and methods of enhancing α7β1 integrin expression by use of the disclosed α7β1 integrin modulatory agents. Methods of prospectively preventing or reducing muscle injury or damage in a subject are also disclosed.
US09980941B2 Quaternary ammonium anti-cholinergic muscarinic receptor antagonists
A method administers quaternary ammonium anti-cholinergic muscarinic receptor antagonists in combination with acetyl-cholinesterase inhibitors to treat either cognitive impairment or acute delirium. This therapy results in a modification of a cognitive disorder or disease, namely a slow down in the disease progression. In one preferred embodiment, the disease is dementia with Lewy Bodies. New formulations for quaternary ammonium anti-cholinergic muscarinic receptor antagonists are also disclosed.
US09980939B2 Composition for enhancing newborn infant cognitive, brain and/or CNS development and method of using same
Disclosed are nutritional compositions generally, and infant formulas specifically, that include a combination of RRR-alpha tocopherol, fat, and protein. The amount of non-RRR alpha tocopherol stereoisomers in the nutritional compositions is limited. Also disclosed are methods of using the compositions to improve cognitive, brain and/or central nervous system development in an individual.
US09980936B2 BH4 antagonists and methods related thereto
The disclosure relates to BH4 inhibitors and therapeutic uses relates thereto. In certain embodiments, the disclosure relates to methods of treating or preventing cancer, such as lung cancer, comprising administering therapeutically effective amount of a pharmaceutical composition comprising a compound disclosed herein or pharmaceutically acceptable salt to a subject in need thereof.
US09980934B2 Monoacylglycerols for use in conjunction with a lipase inhibitor and/or diets low in fat and/or calories
In an embodiment, compositions comprising monoacylglycerols (MAG), such as sn-1(3) MAG, are administered with a lipase inhibitor, such as tetrahydrolipstatin, and/or with a diet low in fat and/or calories. In another embodiment, compositions comprising MAG, such as sn-1(3) MAG, are administered concurrently with a lipase inhibitor, such as tetrahydrolipstatin, and/or with fat-soluble nutrients. The compositions and the methods of using the compositions enhance absorption of fatty acids and fat-soluble nutrients such as fat-soluble vitamins and carotenoids to address nutritional deficiencies due to a weight loss diet used in association with a lipase inhibitor.
US09980933B2 Thyroid hormone analogs and methods of use
Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.
US09980932B2 Valaciclovir and meloxicam combination therapy for functional somatic syndromes
The present invention relates to pharmaceutical compositions comprising a combination of a therapeutically-effective amount of the antiviral compound valaciclovir and a therapeutically-effective amount of the COX-2 inhibitor meloxicam. The invention is further related to methods of treating functional somatic syndromes by administering a therapeutically-effective combination of valaciclovir and meloxicam.
US09980928B2 Hydroxy aliphatic substituted phenyl aminoalkyl ether derivatives
Hydroxy aliphatic substituted phenyl aminoalkyl ether compounds of formula (I), and compositions thereof, are useful as a medicament in the treatment of nervous system diseases and/or the treatment of developmental, behavioral and/or mental disorders associated with cognitive deficits.
US09980927B2 Use of tapentadol for inhibiting and/or treating depression and anxiety
The use of tapentadol (i) in the treatment of pain in a subject suffering from depression and/or from anxiety, and/or (ii) in the treatment or the inhibition of depression or anxiety.
US09980925B2 Xanthohumol in antiarrythmic applications
Methods for modulating Ca2+ signaling in cardiac myocytes by use of xanthohumol are described. Xanthohumol can suppress Ca2+ signaling by suppressing spontaneous activity of the RyR2 receptor. Delivery of xanthohumol to a cardiocyte can be utilized in treatment of cardiac arrhythmia.
US09980924B2 Topical pterostilbene compositions for use in treating UV-induced loss of barrier function in skin
A chemoprotective method for treating, inhibiting or preventing loss of barrier function in skin caused by ultraviolet (UV) light by using an effective amount of pterostilbene is provided. Pharmaceutical and nutraceutical compositions containing pterostilbene suitable for administration to an individual in order to prevent subsequent UV-mediated loss of barrier function in skin are provided.
US09980921B2 Transdermal delivery system containing methylphenidate or its salts and methods thereof
Disclosed herein is a transdermal delivery system comprising methylphenidate or its salt as an active ingredient. Also provided are methods of delivering a therapeutically effective amount of methylphenidate to a subject for the treatment of a disease condition. The disease condition includes a neurological condition such as Attention Deficit Disorder (ADD) and/or Attention Deficit/Hyperactivity Disorder (ADHD). Kits including the transdermal delivery system and methods of making and using the transdermal delivery system are also provided.
US09980913B2 Immunogenic composition
A process of producing an immunogenic particle includes mixing an aqueous solvent A wherein an antigen(s) is/are dissolved and a water-immiscible organic solvent B wherein an amphiphilic polymer(s) whose hydrophobic segment(s) is/are poly(hydroxy acid) is/are dissolved, to form a reversed-phase emulsion; and removing the solvent from the reversed-phase emulsion to obtain an antigen-adjuvant microparticle complex, wherein the aqueous solvent A and/or the water-immiscible organic solvent B contains a surfactant.
US09980911B2 Bioerodible silicon-based compositions for delivery of therapeutic agents
The invention comprises a composition comprising a bioerodible porous silicon-based carrier material wherein the carrier material carries at least one large molecule therapeutic agent and at least one amorphous sugar, optionally further comprising a crystallization inhibitor. The composition may be used in vitro or in vivo to deliver the therapeutic agent, preferably in a controlled fashion over an intended period of time such as over multiple days, weeks or months. The composition may be used for treating or preventing conditions of a patient such as chronic diseases.
US09980908B2 Liposome and method for producing liposome
It is intended to provide a liposome preparation which is a liposome, has a lipid bilayer membrane composed of an inner membrane constituted by a lipid including one or more types of functional lipids (a lipid capable of chemically interacting with another compound such as a charged lipid, a polarizable lipid, a lipid-soluble lipid or a water-soluble lipid) and an outer membrane constituted by a lipid with or without including one or more types of functional lipids, and is characterized in that at least a condition that the amount of any one type of functional lipid contained in the inner membrane is larger than in the outer membrane is satisfied. The liposome preparation is suitable as a liposome for encapsulating a contrast agent (a neutral substance having a hydroxy group), siRNA (an anionic substance) having an anticancer activity or the like. Its encapsulation ratio of drug agents, dispersion stability, control release and the like have been improved.
US09980903B2 Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
Controlled release oral dosage forms are provided for the continuous, sustained administration of a pharmacologically active agent to the upper gastrointestinal tract of a patient in whom the fed mode as been induced. The majority of the agent is delivered, on an extended release basis, to the stomach, duodenum and upper regions of the small intestine, with drug delivery in the lower gastrointestinal tract and colon substantially restricted. The dosage form comprises a matrix of a biocompatible, hydrophilic, erodible polymer with an active agent incorporated therein, wherein the polymer is one that both swells in the presence of water and gradually erodes over a time period of hours, with swelling and erosion commencing upon contact with gastric fluid, and drug release rate primarily controlled by erosion rate.
US09980902B2 Method for treating intestinal fibrosis
A method for treating intestinal fibrosis in a subject, comprising enterally administering a steroid to the subject. The steroid may be in a multiple minibead formulation.
US09980897B2 Organopolysiloxane and powder treatment agent, preparation for external use and cosmetic comprising the same
The present invention provides a novel organopolysiloxane in which a rich hydrophilic property is exhibited, not only superior miscibility with a hydrophilic component and but also a hydrophobic property are exhibited, and superior miscibility with both a silicone oil and a non-silicone oil such as a hydrocarbon oil, an ester oil or the like, and provide various usages of the aforementioned novel organopolysiloxane by developing the superior characteristics thereof such as good surface activity power, a distinctive sensation during use, increased stability and the like. A co-modified organopolysiloxane having a specified chemical structure in which a sugar alcohol-modified group and a long-chain hydrocarbon group are present in one molecule is produced. The co-modified organopolysiloxane is blended, as a surfactant, a powder treatment agent, a gelling agent or the like, or as a cosmetic raw material appropriately together with powder(s), oil agent(s) or the like, in a preparation for external use, and in particular, a cosmetic.
US09980895B2 Cosmetic composition for coating keratin fibres
The present invention relates to an emulsion-type cosmetic composition for coating keratin fibers, comprising: —an aqueous phase, —particles comprising at least one hard wax, preferentially in the form of an aqueous dispersion, having a melting point greater than or equal to 60° C., the hard wax(es) being present at a total content greater than or equal to 10% by weight relative to the total weight of the composition, —at least one emulsifying system capable of dispersing at least the hard wax(es), comprising a non-ionic surfactant with an HLB value at 25° C. greater than or equal to 8, preferably greater than or equal to 10, and —at least one particular anionic associative polymer. The present invention also relates to a method for coating keratin fibers, to a method for preparing a cosmetic composition for coating keratin fibers, to a cosmetic composition for coating keratin fibers which is obtained by means of said production method, and also to a particular use.
US09980893B2 Dye composition comprising a 1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-amine compound
The invention relates to a 1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-amine compound of formula (I) below, addition salts thereof, optical isomers, geometrical isomers and tautomers thereof and/or solvates thereof: in which: .R2, R3, R4, R5, and R7 independently represent: a hydrogen or halogen atom; a C1-C4 alkyl radical; a C1-C4 hydroxyalkyl radical; a carboxyl radical; a (C1-C4)alkoxycarbonyl radical; .R1 and R6, which may be identical or different, represent: hydrogen atom; C1-C10 and preferably Ci-C6 alkyl radical,—optionally interrupted with one or more heteroatoms chosen from O and S or with one or more groups—NR and/or—optionally terminating with at least one group—NX1X2 or at least one group —OX3, .X1 and X2 independently denote—a hydrogen atom, a linear C1-C6 alkyl radical, a branched C3-C6 alkyl radical, a linear C1-C6 hydroxyalkyl radical or a branched C3-C6 hydroxyalkyl radical, X1 and X2 may form, with the nitrogen atom that bears them, a saturated or unsaturated 5- to 8-membered heterocycle, in which one of the ring members may be a heteroatom chosen from O, S and N; the said heterocycle possibly being substituted with one or more linear or branched C1-C4 alkyl or C1-C4 hydroxyalkyl radicals, .X3 denotes—a hydrogen atom—a linear C1-C4 or branched C3-C4 alkyl radical, and .R denotes—a hydrogen atom—a linear C1-C4 alkyl radical.
US09980892B2 Skin care composition
A skin care composition is described comprising water-soluble dye polymer comprising polymer backbone having negatively charged reactive dye substituent covalently bound thereto; and cosmetically acceptable carrier. The dye polymer is present in amount of 0.00001 to 0.1% in terms of reactive dye substituent by weight of the skin care composition. The composition is useful for providing cosmetic benefits such as skin lightening, evening skin tone and masking blemishes.
US09980887B2 Compositions for use in treatment of hyperpigmentation and methods of use thereof
Compositions containing an effective dermatological disease-treating or dermatological condition-treating active agent and a pharmaceutically-acceptable carrier or vehicle are disclosed. Methods of using the compositions are also disclosed.
US09980881B1 Method and system of personalizing a pill tray
A pill tray includes a cover attached to a base portion that is operable to move between an open position and a closed position, the cover including an inside surface having at least a first slot adjacent a first end of the cover and a second slot adjacent a second end of the cover opposite the first end. A personalized information sheet is dimensioned and configured to be removably secured to the cover of the pill tray by inserting a first end of the personalized information sheet into the first slot of the cover and a second end of the personalized information sheet into the second slot of the cover such that the personalized information sheet is visible to a user when the cover is in the open position.
US09980879B2 Automated filling systems and methods
Various embodiments of the present invention are directed to transferring fluidic media from a vial to a reservoir. In various embodiments, fluidic media may be transferred from the vial to the reservoir by moving a housing portion to move a plunger head located in the reservoir to draw fluidic media from the vial to the reservoir. In other embodiments, fluidic media may be transferred from the vial to the reservoir while the reservoir is held by a holding unit and vibrated by a vibrator to remove air from the fluidic media. In some embodiments, fluidic media may be transferred from the vial to the reservoir by moving a handle operatively connected to a bias member for assisting with the transfer of fluidic media. In other embodiments, the transfer of fluidic media may be assisted by a bias member and a needle connecting atmosphere and the vial.
US09980876B2 Methods and devices to provide persistent hot tactile experience
The present disclosure provides an electric heating device which can provide persistent hot tactile experience in male masturbation and meanwhile keep the insertion passage tight as long as possible. The device includes a electric heating kettle having at least two masturbator chambers and one lubrication chamber, a coaster, a transfer pipette having long and thin tube, a electrical thermometer. The present disclosure also provides a method to use hot masturbators rotationally. The present disclosure further provides a lubrication bottle embed with a transfer pipette and electric heating function.
US09980874B2 Carrying device for an end user of a walker
A carrying device is provided to carry at least one article for an end user of a walker while the end user is utilizing the walker. The carrying device includes a base having a first end, a second end, and a carrying surface extending between the first and second ends. The carrying surface is adapted to removably retain the at least one article for the end user. The carrying device further includes a support arm coupled to and extending outwardly from the second end of the base. The support arm is configured to support the at least one article when the at least one article is retained on the carrying surface at a position proximate to the second end of the base.
US09980873B2 And use of a leg support exoskeleton
A leg support exoskeleton is strapped on as wearable device to support its user during squatting. The exoskeleton includes a knee joint connected to a first line and a second link, which is configured to allow flexion and extension motion between the first link and the second link. A force generator has a first end that is rotatably connected to the first link. A constraining mechanism is connected to the second link and has at least two operational positions. In a first operational position, the second end of the force generator engages the constraining mechanism, where the first link and the second link flex relative to each other. In a second operational position, the second end of the force generator does not engage the constraining mechanism; the first link and the second link are free to flex and extend relative to each other.
US09980867B2 Limb positioner
The invention features a kit comprising components for a device for positioning and supporting a limb (e.g., an arm or leg) of a patient. The invention also features methods of assembling and adjusting a limb positioning device.
US09980866B2 Equipment for the raising of a lying person
Equipment for raising of a lying person. The equipment comprises: a seat (1), a backrest (2), which from a first position can be passed to a second position behind the back of the person, and a chassis (3) with an upper end to which the seat is connected and a lowermost end adapted to rest on a surface such as a floor. The equipment is to be placed on the surface positioned to the person such that the seat is placed under the behind of the person and from this first position the equipment with the person can be passed to a second position in which the chassis with its lower end rests on the surface such that the seat and backrest is raised relative to the surface e.g. to take a chair-like posture or a catapult position i.e. an upright position in which the person will be assisted to a standing position.
US09980864B2 Calf bumper system
A calf bumper that covers an exposed metal bracket used to hold a leg rest on a wheelchair. The protective device is made of a flexible elastomeric material and is separable on one side with a cavity for the leg rest bracket plate and a central hole to encompass the leg post and the bracket pin. When deployed the bumper provides protective buffer surrounding the exposed bracket reducing the risk of injuries such as scrapes and skin tears caused by exposed wheelchair leg rest brackets.
US09980861B2 Absorbent garment
A washable, reusable garment for retention of body fluids when worn on a person's lower body part. The garment has a crotch portion and a body portion. The crotch portion has an absorbent composite, and a pocket adapted for receiving a removable absorbent pad. The body portion has a waist opening and is seamless except where attached to the crotch portion. The body portion and the crotch portion together form first and second leg openings.
US09980859B2 Absorbent article having a fastening system with improved flexibility
An absorbent article is provided that can include a fastening system configured to attach the rear waist region to the front waist region to define a wear configuration of the absorbent article. The fastening system can comprise a primary fastening system and a secondary fastening system, the secondary fastening system including at least one secondary first fastening component and at least one secondary second fastening component. A region of flexibility can be provided between adjacent components of the absorbent article between the at least one secondary first fastening component and the bodyside liner in an area under the at least one secondary first fastening component.
US09980858B2 Absorbent article with improved garment-like character
A disposable absorbent article may include a chassis comprising a liquid permeable topsheet, a backsheet, and an absorbent core disposed between the topsheet and backsheet; and an ear joined to the rear waist region of the chassis such that at least a portion of said ear extends laterally outward from the longitudinal edge of the chassis in the rear waist region. The article further comprises a fastening system including an engaging member disposed proximate to distal edge of the ear and a receiving member disposed on the chassis in the front waist region, wherein the ear interconnects the front waist region and the rear waist region upon engagement of the engaging member with the receiving member. The ear has a Front Edge Displacement and a Rear Edge Displacement such that a sum of the Front Edge Displacement and the Rear Edge Displacement is no greater than about 12 mm.
US09980857B2 Absorbent article with leg cuffs
Disclosed is an absorbent article including a water permeable topsheet, a water impermeable backsheet, an absorbent core, an outer cover layer, and a pair of outer cuffs for providing leg gasketing function, wherein the pair of outer cuffs includes a cuff sealing disposed in a longitudinally extending manner, the cuff sealing located transversely between the absorbent core and the longitudinal side edge of the backsheet.
US09980851B2 Instrument for stimulating or irritating and/or abrasively treating and/or polishing a membrane or surface or inner surface in the human or animal eye
The invention relates to an instrument for stimulating or irritating and/or abrasively treating and/or polishing a membrane or surface or inner surface in the human or animal eye, comprising a handle (1), which comprises an actuating element (2), and a probe (3), which adjoins the handle (1) and which is open at the free distal end, for introducing into the eye. The invention is characterized in that the probe (3) comprises a loop (4) in the interior, and the loop can be at least slightly pushed out of the probe (3) and pushed or pulled back into the probe (3) by means of the actuating element (2).
US09980848B2 Force distribution method and apparatus for neonates at risk of cranial molding
A force distribution apparatus and method are presented. Various embodiments of the disclosed apparatus include a plurality of layers configured and oriented to be deployed on a subject in a manner that disperses forces and lowers peak pressures experienced by the subject when resting on a surface, which tends to minimize risks of deformation and local ischemia. An innovative combination of novel construction methods and material selections produce an apparatus that possesses an inherent three-dimensional shape despite being built from essentially flat components, while also retaining an ability to effectively distribute forces and reduce pressures.
US09980846B2 Orthosis and corrective joint
An orthosis for stabilizing a joint has a joint rail having a first and a second rail portion which can be pivoted relative to each other about a joint axle. The orthosis has a pressure member which can be adjusted by a relative pivoting of the two rail portions about the joint axle in the direction towards and counter to the joint to be stabilized. One of the two rail portions has a cam disc, and the other of the two rail portions has a rotor which is guided on the cam disc, wherein the cam disc or the rotor is axially fixed in position on the correction pad.
US09980845B2 Heel protector and corresponding rehabilitation systems and methods for using the same
A device (100) includes a leg engaging section (101) and a foot engaging section (102) intersecting at a heel receiver (103). The leg engaging section and the foot engaging section define a leg insertion aperture (104). A compressible cushion layer (402) is disposed at least in the leg engaging section. At least one bolster tube (401) is disposed interior the leg engaging section. The bolster tube (401) can be selectively removable through one or more apertures (1105,1106).
US09980844B2 Flexible joint wrap
A flexible joint wrap includes a heat exchange bladder, which provides fluid circulation and compression to a joint. The joint wrap includes upper and lower sections for attachment above and below a joint. The bladder has an opening at a center section which provides flexibility of the bladder. The heat exchange bladder may be enclosed in a removable cover designed to conform to the shape of the bladder. The cover and bladder are formed with an opening in alignment with the joint to provide flexibility to the wrap. The cover may be formed of a fluid repellant inner lining to prevent fluid from the joint from soiling the bladder. The cover may further comprise a nylon loop outer surface to allow the upper and lower sections to be easily attached and adjusted.
US09980843B2 Joint support adjustable device
A joint support adjustable device is provided, including a base, two connecting members and a positioning mechanism. The base has a center and two side walls distanced from and corresponding to each other, and at least one said side wall is formed with a plurality of toothed recesses. Each said connecting member is for being connected with a human limb. The positioning mechanism has a fixation member disposed between the two side walls and at least one adjusting mechanism connected with the base, each said adjusting mechanism has a positioning assembly for being operated from outside and movable about the center, at least one of the positioning assembly and the fixation member is magnetic to attract the other so that the positioning assembly has a tendency to move toward the center.
US09980841B2 Devices and systems configured to fit around a tissue using the same
Devices and systems to fit around a tissue or organ and methods of using the same. In at least one embodiment of an implantable device of the present disclosure, the implantable device comprises a first engaging component comprising a first rigid inner plate at least partially surrounded by a first flexible coating, a second engaging component comprising a second rigid inner plate at least partially surrounded by a coating selected from the group consisting of the first flexible coating and the second flexible coating, a first c-ring and a second c-ring coupled to the engaging components, and a cover flap coupled to either the first engaging component or the second engaging component and capable of either further coupling to the second engaging component when initially coupled to the first engaging component or further coupling to the first engaging component when initially coupled to the second engaging component.
US09980840B2 Delivery device with an expandable positioner for positioning a prosthesis
A prosthesis delivery device comprises a cannula having an expandable positioning device disposed at the proximal end thereof. A prosthesis is retained on the cannula distal of the expandable device. Expansion of the expandable device retains and centers the delivery device and the prosthesis carried thereon in the vessel and allows repositioning of the prosthesis without contacting the proximal end of the prosthesis with the vessel walls prior to deployment.
US09980839B2 Balloon catheter for multiple adjustable stent deployment
A catheter configured to carry one or more stents and having an inflatable balloon for expanding a stent surrounding the balloon. The catheter is characterized in having a positioner for moving the one or more stents relative to the balloon from a first position in which the stent does not surround the balloon to a second position in which the stent surrounds the balloon. Also disclosed is a method for deploying a stent at a desired location in the vascular system.
US09980834B2 Low profile non-symmetrical stent
Various stents and stent-graft systems for treatment of medical conditions are disclosed. In one embodiment, an exemplary stent-graft system may be used for endovascular treatment of a thoracic aortic aneurysm. The stent-graft system may comprise proximal and distal components, each comprising a graft having proximal and distal ends, where upon deployment the proximal and distal components at least partially overlap with one another to provide a fluid passageway therebetween. The proximal component may comprise a proximal stent having a plurality of proximal and distal apices connected by a plurality of generally straight portions, where a radius of curvature of at least one of the proximal apices may be greater than the radius of curvature of at least one of the distal apices. The distal component may comprise a proximal z-stent coupled to the graft, where the proximal end of the graft comprises at least scallop formed therein that generally follows the shape of the proximal z-stent. Further, the distal component may comprise at least one z-stent stent coupled to the distal end of the graft and extending distally therefrom that reduces proximal migration of the distal component.
US09980833B2 Uniform expandable and collapsible stent
A modified double helical and braided (platted) helical wire stent is described that provides for uniform collapsing and expansion of the stent body such that the stent collapses and expands in a uniform, predictable manner, reduces foreshortening, and is durable, stable, and reliable.
US09980832B2 Pararenal and thoracic arch stent graft and methods for use
Example stent grafts and methods for placement thereof are provided. An example stent graft may include (a) a main body stent graft defining a lumen that has a first end and a second end, (b) a diaphragm coupled to the main body stent graft, where the diaphragm defines at least three openings and (c) at least three stent graft extensions each defining a lumen, where a first end of each of the three stent graft extensions is coupled to one of the three openings.
US09980831B2 Ureteral stent
A ureteral stent comprises an internal portion, which comprises a first polymer, and an external portion, which comprises a second polymer. The external portion surrounds the internal portion and has a plurality of radial projections that extend along the length of the ureteral stent. The second polymer has a Shore D hardness of 20-40 Shore D. The first polymer has a Shore D hardness that is at least 10 units greater than the Shore D hardness of the second polymer.
US09980824B2 Intervertebral implants and related methods of use
A method of implanting an intervertebral spacer may include positioning the intervertebral spacer within an intervertebral space defined by adjacent vertebral bodies. The intervertebral spacer may include a plurality of bores, and each of the plurality of bores may be configured to receive either a linear fastening element or a curvilinear fastening element. The method also may include selecting a first fastening element from a group including linear fastening elements and curvilinear fastening elements, and inserting the first fastening element into a first bore of the plurality of bores such that the first fastening element is inserted into one of the adjacent vertebral bodies to secure the intervertebral spacer within the intervertebral space.