| Document | Document Title |
|---|---|
| US09885047B2 |
Modulation of TMPRSS6 expression
Disclosed herein are antisense compounds and methods for modulating TMPRSS6 and modulating an iron accumulation disease, disorder and/or condition in an individual in need thereof. Iron accumulation diseases in an individual such as hemochromatosis or β-thalassemia can be ameliorated or prevented with the administration of antisense compounds targeted to TMPRSS6. |
| US09885046B2 |
Methods of inducing insulin production
The present invention provides a method of inducing insulin production in a cell by up-regulating a target gene involved in insulin production in said cell using an saRNA (short activating ribonucleic acid) which specifically down-regulates a target antisense RNA transcript present in said cell, wherein (i) said target RNA transcript is complementary to a sequence located on the coding strand of the target gene between 1000 nucleotides upstream and 1000 nucleotides downstream of the transcription start site of the target gene; and (ii) said sRNA is a single or double stranded RNA molecule up to 30 nucleotides in length comprising a sequence of at least 13 nucleotides which has at least 95% complementarity to a region of the target transcript. Also provided are certain saRNA molecules and uses thereof, particular medical uses, and induced cells and uses thereof. |
| US09885045B2 |
Methods and compositions for modulating apolipoprotein (a) expression
Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a) or Lp(a). Certain diseases, disorders or conditions related to apo(a) or Lp(a) include inflammatory, cardiovascular and/or metabolic diseases, disorders or conditions. The antisense compounds disclosed herein can be used to treat such diseases, disorders or conditions in an individual in need thereof. |
| US09885042B2 |
miR-92 inhibitors and uses thereof
The present invention provides oligonucleotide inhibitors of miR-92 and methods of using said inhibitors for inhibiting the function and/or activity of miR-92 in a subject in need thereof. The present invention also provides methods for evaluating or monitoring the efficacy of a therapeutic for promoting wound healing and selecting a subject for treatment with a therapeutic that modulates miR-92 function and/or activity. |
| US09885041B2 |
Modulation of BCL11A for treatment of hemoglobinopathies
The invention relates to methods and uses of modulating fetal hemoglobin expression (HbF) in a hematopoietic progenitor cells via inhibitors of BCL11A expression or activity, such as RNAi and antibodies. |
| US09885036B2 |
Double-stranded polynucleotide
It is intended to provide a double-stranded polynucleotide that is resistant to RNase and has RNA interference effect, etc. The present invention provides a double-stranded polynucleotide comprising sense and antisense strands comprising polynucleotides comprising a nucleotide unit of DNAs and 2′-O-methyl RNAs alternately combined. |
| US09885034B2 |
Methods and compositions for nucleic acid analysis
Provided herein are methods, compositions, and kits for assays, many of which involve amplification reactions such as digital PCR or droplet digital PCR. The assays may be used for such applications as sequencing, copy number variation analysis, and others. In some cases, the assays involve subdividing a sample into multiple partitions (e.g., droplets) and merging the partitions with other partitions that comprise adaptors with barcodes. |
| US09885029B2 |
Polypeptides having xylanase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| US09885028B2 |
Carbohydrate binding modules with reduced binding to lignin
Provided is a modified Family 1 carbohydrate binding module (CBM) comprising amino acid substitutions at one or more of positions 10, 11, 12, 14, 17, 21, 24, 29, 31, 33, and 37, said position determined from alignment of a Family 1 CBM amino acid sequence with SEQ ID NO: 30, and exhibiting from about 50% to about 99.9% amino acid sequence identity to SEQ ID NO: 30. Also provided are modified glycosidase enzymes comprising the modified Family 1 CBM, genetic constructs and genetically modified microbes for expressing the modified Family 1 CBM or modified glycosidase enzyme. The modified Family 1 CBM confers reduced lignin binding and/or increased hydrolyzing activity in the presence of lignin to the modified glycosidase enzyme, which may be used in a process for hydrolyzing cellulose or hemicellulose in the presence of lignin. |
| US09885024B2 |
PEG-urate oxidase conjugates and use thereof
A naturally occurring or recombinant urate oxidase (uricase) covalently coupled to poly(ethylene glycol) or poly(ethylene oxide) (both referred to as PEG), wherein an average of 2 to 10 strands of PEG are conjugated to each uricase subunit and the PEG has an average molecular weight between about 5 kDa and 100 kDa. The resulting PEG-uricase conjugates are substantially non-immunogenic and retain at least 75% of the uricolytic activity of the unmodified enzyme. |
| US09885020B2 |
ORF7 deficient varicella virus, vaccine comprising the virus and use thereof
Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus. |
| US09885011B2 |
V-shaped light distributor system
A sun-tracking light distributor for a photosynthetic culture in an aqueous liquid, comprising: two light distribution walls made of a transparent material, creating an elongated V-shaped channel adapted to receive the sunlight and to be partly immersed in the aqueous liquid, the sun-tracking light distributor has a center of buoyancy, a vertical passing through the center of buoyancy defines an axis of flotation, and a pivot axis of the sun-tracking light distributor is offset relative to the axis of flotation. Owing to the offset pivot axis, the orientation of the light distributor is changed by varying the level of aqueous liquid, thus allowing a tracking of the sun's altitude. |
| US09885007B2 |
Wax forms with permanent hardware
A wax form, such as a candle, capable of being decorated or adorned with ornamentation using hardware embedded inside the wax form so as to be inconspicuous. The hardware comprises a connector that is flush with the perimeter surface of the candle so that ornamentation can be attached to the connector; thereby, allowing the ornamentation hang on the perimeter surface of the wax form. The connector can utilize a variety of fastening systems to connect to the ornamentation, such as a magnet system, a resistance fit system, a screw fit system, and the like. |
| US09885004B2 |
Method for improving engine fuel efficiency
A method for improving fuel efficiency and reducing frictional properties while maintaining or improving deposit control, in an engine lubricated with a lubricating oil by using as the lubricating oil a formulated oil. The formulated oil has a composition including from 75 to 95 wt % of lubricating oil base stock including a Group I base stock or a combination of a Group III, Group IV and Group V base stock including from 30 to 35 wt % Group III, 45 to 55 wt % Group IV and 0 to 5 wt % Group V and a friction modifier mixture comprising a polymeric ethoxylated fatty acid ester at from 0.1 to 1.0 wt. % and a mixed glyceride ester at from 0.1 to 1.0 wt. % of the formulated oil. The lubricating engine oils are useful in internal combustion engines including direct injection, gasoline and diesel engines. |
| US09885000B2 |
Renewable hydrocarbon composition
The present invention provides a composition comprising 8-30 mass % of C4-12 linear alkanes, 5-50 mass % of C4-12 branched alkanes, 25-60 mass % of C5-12 cycloalkanes, 1-25 mass of C6-12 aromatic hydrocarbons, no more than 1 mass % of alkenes, and no more than 0.5 mass % in total of oxygen-containing compounds; wherein the total amount of C4-12 alkanes is 40-80 mass %, and the total amount of C4-12 alkanes, C5-12 cycloalkanes and C6-12 aromatic hydrocarbons is at least 95 mass %; and wherein the amounts are based on the mass of the composition. Also provided is a method for producing the composition comprising the step of hydroprocessing a biological feedstock using a catalyst and the step of fractionating the product of the hydroprocessing step. |
| US09884997B2 |
Oil from oil sands extraction process
A system for extracting bitumen from oil sands includes an extractor tank having a reaction chamber. An input port is provided at the upper end of the extractor tank for the purpose of introducing oil sand into the reaction chamber. A liquid extractant is heated and then pumped, under pressure, into the reaction chamber through a plurality of jet inlets to suspend the oil sand in the extractant, as a fluidized bed inside the reaction chamber. After reactions, an extract that contains both extractant (solvent) and bitumen, is separated from the sand. A vibratory centrifuge is connected to an outflow port of the extractor tank to receive the sand and remove any residual extractant from the sand. An evaporator and distillation column are provided to remove the extract from the reaction chamber and separate the extractant from the bitumen. |
| US09884994B2 |
Method for preventing soil erosion
Provided is a method for preventing soil erosion in which a nonionic guar and/or a cationic guar is applied on or into the soil. A method for preventing water runoff of a soil in which a nonionic guar and/or a cationic guar is applied on or into the soil is also provided. A treated soil against the soil erosion susceptible to be obtained by the method for preventing soil erosion in which a nonionic guar and/or a cationic guar is applied on or into the soil is also provided. |
| US09884990B2 |
Phosphor, method of producing the same, and light emitting apparatus
There are provided a phosphor which is a divalent europium-activated oxynitride phosphor substantially represented by General formula (A): EuaSibAlcOdNe, a divalent europium-activated oxynitride phosphor substantially represented by General formula (B): MIfEugSihAlkOmNn or a divalent europium-activated nitride phosphor substantially represented by General formula (C): (MII1-pEup)MIIISiN3, having a reflectance of light emission in a longer wavelength region of visible light than a peak wavelength of 95% or larger, and a method of producing such phosphor; a nitride phosphor and an oxynitride phosphor which emit light efficiently and stably by the light having a wavelength ranging from 430 to 480 nm from a semiconductor light emitting device by means of a light emitting apparatus using such phosphor, and a producing method of such phosphor; and a light emitting apparatus having stable characteristics and realizing high efficiency. |
| US09884982B2 |
Abrasive grain based on melted spherical corundum
An abrasive grain made from melted spherical corundum where the abrasive grain consists of a spherical corundum core, coated with an encircling layer of a binder and fine-grained abrasive solid particles. |
| US09884980B2 |
PVC self-adhesive floorboard with water-resistant glue
A self-adhesive floorboard with water-resistant glue comprises from a top to a bottom sequentially a main body layer, an isolation layer and the water-resistant glue, wherein each component proportion of component composition of the water-resistant glue based on a weight percentage is: 34-38% for a styrene-isoprene-styrene block copolymer, 46.4-50.4% for C5 hydrogenated petroleum resin, 13-17% for cycloalkyl rubber extender oil and 0.5-0.6% for a hindered phenol antioxidant. The isolation layer between the main body layer and the water-resistant glue is a PVC film of OPHR. The water-resistant glue of the PVC self-adhesive floorboard with the water-resistant glue is provided with a water-resistance function, and can prevent a plasticizer from drifting away from the PVC floorboard to affect stickiness of the water-resistant glue. |
| US09884976B1 |
Coating compositions and methods, and articles coated with same
Described are sealing primer compositions that can be used to reduce paint defects such as pops or vapor boil on painted plastic substrates, as well as related methods for sealing plastic substrates, and sealed plastic substrates. Sealing primer compositions of the invention include a functionalized polydiene polymer such as a hydroxylated or other functional-group-containing polybutadiene polymer. |
| US09884975B2 |
Ink jet ink composition, ink accommodation body and ink jet recording method
An ultraviolet curing ink jet ink composition includes a trifunctional or tetrafunctional (meth)acrylate having a pentaerythritol skeleton; and inorganic metal-based fine particles as a color material, in which the viscosity is 8 to 22 mPa·s at 20° C. |
| US09884973B2 |
Active energy ray-curable inkjet ink and ink set
The present disclosure relates to an active energy ray curable inkjet ink for use in a single pass printing inkjet system, the inkjet ink containing a colorant, a monomer and at least one initiator, wherein the sum of the integrated value(s) of absorbance across wavelengths from 380 to 410 nm of the initiator(s) is at least 35, and 0.02≦amount of initiator/amount of monomer≦0.50 (weight ratio) is satisfied. The disclosure also relates to an ink set including the ink. The present disclosure is able to show printed articles that exhibit no wrinkling or tack, excellent color reproducibility, and reduced amounts of residual components within the cured film of printed articles, while offering high productivity, and can also show an active energy ray-curable inkjet ink cured film which has a low residue ratio and is of low-odor, while exhibiting similar print quality and productivity to existing printing systems. |
| US09884970B2 |
Coating composition for preventing collapse of capacitor
Disclosed herein is a coating composition for preventing the collapse of a capacitor, comprising a silane compound or a phosphorus compound. The coating composition can adjust a contact angle with regard to water on a substrate, thereby preventing the collapse of capacitor patterns on the substrate. |
| US09884969B2 |
Poly-rotaxane compound, photocurable coating composition, and coating film
The present invention relates to a novel polyrotaxane compound having a specific chemical structure, a photocurable coating composition that may provide a coating material having excellent mechanical properties such as scratch resistance, chemical resistance, abrasion resistance, and the like, and excellent self-healing capability, and a coating film obtained from the photocurable coating composition. |
| US09884967B1 |
Non-stick marine coating
Methods and formulations for nonstick marine coatings and compounds are disclosed. Embodiments of the invention provide nonstick marine coatings and compounds that include an adhesion reduction component that is sufficiently homogenous and sufficiently non-viscous to be incorporated into one or more other components of the coating compound. |
| US09884964B2 |
Asphalt foam collapse test methods and related apparatus
The disclosure relates to asphalt foam collapse test methods and related apparatus for the measurement and determination of foamed asphalt binder quality, in particular warm-mix asphalt. Various asphalt binder/foam quality indicators can be measured according to the disclosure, such as bubble size distribution, bubble surface area, foam expansion ratio, foam half-life, foam index, as well as normalized parameters related to the same. The disclosed methods and apparatus permit the repeatable characterization and formation of foamed asphalt compositions, enabling the skilled artisan to form foamed asphalt/aggregate compositions of known, repeatable quality. This enhances the ability to form WMA foamed asphalt concrete with controlled and favorable properties selected for the particular environmental conditions (e.g., climate-, weather-, and/or traffic-related) where the concrete is to be used. |
| US09884961B2 |
Phosphazene flame retardant polycarbonate compounds
A non-halogenated flame retardant polycarbonate compound is disclosed. The compound comprises a polycarbonate, a non-halogenated, non-migrating, non-plasticizing flame retardant adduct. The compound can achieve a UL 94 rating of V-0 at a thickness of at least 3.2 mm and otherwise achieves no dripping/igniting of the cotton indicator during that test. The adduct is formed from an allyl-functional phenoxyphosphazene and a hydride-functional polysiloxane. |
| US09884960B2 |
White heat-curable epoxy resin composition, optical semiconductor element case made of the white heat-curable epoxy resin composition and optical semiconductor device comprised of the case
Provided are a white heat-curable epoxy resin composition having a high strength, high toughness and superior heat resistance; and a semiconductor device whose light receiving and other semiconductor elements are encapsulated by a cured product of such composition. The composition includes: (A) a prepolymer obtained by heating, melting and mixing components (A-1) triazine derivative epoxy resin, (A-2) acid anhydride and (A-3) acrylic block copolymer so as to react them at an epoxy group equivalent in the component (A-1)/acid anhydride group equivalent of the component (A-2) ratio of 0.6 to 2.0; (B) a white pigment including at least a titanium oxide; (C) an inorganic filler; (D) a curing accelerator; and (E) an antioxidant. |
| US09884959B2 |
Epoxy-based resin composition for composite materials
A curable, epoxy-based resin composition that can be combined with reinforcement fibers and then cured to form a cured product that is excellent in toughness and exhibits high Open-Hole Tensile (OHT) strength. According to one embodiment, the resin composition contains a Bisphenol F difunctional epoxy, an anthracyl compound, a tri-functional epoxy, a thermoplastic polymer, and an amine-containing curing agent. |
| US09884958B2 |
Propylene-based block copolymer
An object of the present invention is to prevent an occurrence of flow-mark molding defects to improve an appearance of molded articles, and as a means for achieving the object, a propylene-based block copolymer is used as an appearance improver, the copolymer comprising 80 to 60% by weight of crystalline propylene polymer portion which has an intrinsic viscosity [η]p of 0.90 dL/g or less and 20 to 40% by weight of propylene/ethylene random copolymer portion which has an ethylene content of 35 to 50% by weight and an intrinsic viscosity [η]c of 7.0 dL/g or higher ([η]c/[η]p being 7.5 to 30), in which the propylene-based block copolymer has a MFR of 10 to 50 g/10 min. |
| US09884956B2 |
Thermoplastic elastomer composition
There are provided a thermoplastic elastomer composition from which a molded article excellent in softness, flame retardancy, tensile properties, and appearance can be obtained and which is excellent in flowability, and a molded article thereof. The thermoplastic elastomer composition includes a thermoplastic elastomer obtained by reacting an ethylene copolymer comprising monomer units derived from ethylene and monomer units derived from at least one selected from the group consisting of propylene and α-olefins having 4 to 10 carbon atoms (component (A)), a propylene polymer (component (B)), and a crosslinking agent, a phosphoric acid salt compound (component (C)), a metal oxide including a metal having an atomic weight of 22 to 64 or a metal hydroxide including a metal having an atomic weight of 22 to 64 (component (D)), and a polyhydric compound (component (E)). |
| US09884954B2 |
Random mat and fiber-reinforced composite material shaped product
A random mat contains reinforcing fibers having an average fiber length of 3 to 100 mm and a thermoplastic resin, the reinforcing fiber contains reinforcing fiber bundle (A) defined as the bundle composed of the reinforcing fibers of a critical number of single fiber (defined by the following formula (1)) or more, an average thickness of the reinforcing fiber bundles (A) is 100 μm or less, and the number (n) of the reinforcing fiber bundles (A) per unit weight (g) of the reinforcing fibers satisfies the following formula (I): Critical number of single fiber=600/D (1) (wherein D is the average fiber diameter (μm) of the reinforcing fiber), and 0.65×104/L |
| US09884944B2 |
Remendable interfaces for polymer composites
Functionalized polymer matrix and/or reinforcement materials that are capable of a thermoreversible Diels-Alder reaction are useful for making composite materials. Also disclosed is a composite material which includes one or both of functionalized reinforcement materials and functionalized polymer matrix materials, as well as a method for repairing a composite material including the step of thermally treating the composite material at a temperature sufficient to react a functionality on one of the reinforcement material and the polymer matrix material with another functionality via a Diels-Alder reaction. A method of making a composite material including functionalizing one or both of a reinforcing material and a polymer matrix material with a first reactive group, providing a second reactive group capable of undergoing a Diels-Alder reaction with the first reactive group and reacting the first and second reactive groups to form a composite material, is also described. |
| US09884942B2 |
Maleimide resins
A curable polymer composition comprising: (A) a thermoset maleimide resin precursor component; and further comprising one or both of: (B) an arylsulphone-containing maleimide component; and (C) a polyarylpolymer thermoplastic toughening agent component, wherein in the absence of component (B), said component (C) comprises one or more maleimide pendant and/or end groups, and thermoset resins and composites derived therefrom. |
| US09884940B2 |
Polythioaminals with tunable modulus
Compounds include boronate ester polythioaminals with substituents that include hydrogen, fluorine or substituted or unsubstituted alkyls. The boronate ester polythioaminals have number average molecular weight or weight average molecular weight between about 2,000 to about 160,000. |
| US09884936B2 |
Photoactive resins, radiation curable compositions and radiation curable inks
The present invention is directed to photoactive resins employed in radiation curable compositions and ink. The radiation curable compositions include mono or multi-functional acrylates, an amine and the above-mentioned photoactive resin. Radiation curable inks at least include the components of the radiation curable composition in addition to colorants. |
| US09884933B2 |
Comb copolymer and process for the preparation thereof
A comb copolymer having a backbone of 2-acrylamido-2-methylpropanesulfonic acid, with grafted lateral side segments of poly(N-alkylacrylamide) or poly(N,N-dialkylacrylamide), is provided. A process for the preparation of the comb copolymer includes reacting a compound of formula (II) with a compound of formula (III) in a (tert-butanol)-water mixture, to obtain a poly(N-alkylacrylamide) or poly(N,N-dialkylacrylamide) telomere of formula (I); reacting in tert-butanol the telomer of formula (I) with an acid chloride of formula (IV) to obtain a solution of the macromonomer of formula (V); and copolymerizing in tert-butanol the macromonomer of formula (V) with an ammonium salt of 2-acrylamido-2-methylpropanesulfonic acid. |
| US09884926B2 |
Metallocene catalyst for preparing a high molecular weight polyolefin and a preparation method thereof
The present invention relates to a metallocene compound having novel structure which can provide various selectivity and activity to polyolefin copolymers, a preparation method thereof, and a preparation method of polyolefin using the metallocene compound. |
| US09884925B2 |
Silyl bis(hexamethylindenyl) complexes of group IVA metals as polymerization catalysts
Novel Si-bridged metallocene catalysts of formula I defined herein are disclosed, as well as their use in olefin polymerisation reactions. |
| US09884919B2 |
Methods of treatment with bispecific antibodies binding to beta-klotho and fibroblast growth factor receptor 1
The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB. |
| US09884917B2 |
Anti c-Met antibodies
The present invention relates to antibodies that specifically bind to the human c-Met receptor protein and that act as strict antagonists of hepatocyte growth factor (HGF)-mediated activation of the c-Met receptor and also inhibit HGF-independent activation of the human c-Met protein. |
| US09884911B2 |
Compounds and methods for treating pain
This disclosure provides compositions and methods for controlling pain. In particular the disclosure provides a method for controlling pain comprising co-administration of an NGF antagonist and a TNFα antagonist. The NGF antagonist and the TNFα antagonist can be separate molecules or part of a multifunctional polypeptide, e.g., a multispecific binding molecule that comprises an NGF antagonist domain and a TNFα antagonist domain. This disclosure also provides multifunctional polypeptides, e.g., multispecific binding molecules, comprising an NGF antagonist domain, and a TNFα antagonist domain. The method provides improved pain control. Administration of an NGF antagonist and a TNFα antagonist as provided herein can control pain in the subject more effectively than an equivalent amount of the NGF antagonist or the TNFα antagonist administered alone. |
| US09884899B2 |
Methods for treating fibrosis using CRP antagonists
The application provides methods for determining a patient's risk for developing fibrosis or a fibrosis-related disorder. Concentrations of C reactive protein (CRP) and serum amyloid protein (SAP) are measured from a biological sample to determine the SAP-to-CRP ratio. This ratio can then be compared with one or more SAP-to-CRP reference ratios to determine a patient's risk for developing a fibrosis related disorder. The diagnostic methods can also be used to determine the severity of fibrosis in a patient afflicted with such a disease. Furthermore, methods for treating patients having a fibrosis-related disorder are provided. For example, a patient that has a lower SAP-to-CRP ratio than one or more reference values may be treated with an SAP agonist and/or CRP antagonist to treat or prevent a fibrosis disorder. The methods may further comprise determining the R131/H131 polymorphism of FcγRIIA as a risk factor for developing fibrosis or a fibrosis-related disorder. |
| US09884897B2 |
Method for producing protein
It has been believed that promoting the assembly of polysomes composed of many ribosomes attached to mRNA is very effective for highly efficient protein synthesis. However, the mechanism for p180 protein's capability of promoting polysome formation has been yet to be elucidated.The inventors of the present application newly discovered SF3b4 protein as a protein that specifically interacts with the coiled-coil domain of p180 protein, a responsible region for its capability of promoting polysome formation, and which is capable of promoting mRNA localization to an endoplasmic reticulum (ER). The inventors also found that, in cells capable of highly expressing both p180 protein and a protein promoting mRNA localization to an endoplasmic reticulum (ER) (e.g., SF3b4 protein), the mRNA localization to the endoplasmic reticulum can be significantly elevated so that the secretory capacity in cultured cells can be enhanced. Further, the inventors demonstrated that when a particular nucleotide sequence is inserted into an expression plasmid, SF3b4 protein exhibiting protein expression enhancing ability can be localized onto the endoplasmic reticulum membrane, and the mRNA distribution in polysomes can be shifted towards heavier fractions, whereby the secretory capacity in cells can be enhanced. |
| US09884896B2 |
Polynucleotides and methods for making plants resistant to fungal pathogens
This invention relates to polynucleotide sequences encoding a gene that can confer resistance to the plant pathogen Colletotrichum, which causes anthracnose stalk rot, leaf blight and top dieback in corn and other cereals. It further relates to plants and seeds of plants carrying chimeric genes comprising said polynucleotide sequences, which enhance or confer resistance to the plant pathogen Colletotrichum, and processes of making said plants and seeds. The invention further presents sequences that can be used as molecular markers that in turn can be used to identify the region of interest in corn lines resulting from new crosses and to quickly and efficiently introgress the gene from corn lines carrying said gene into other corn lines that do not carry said gene, in order to make them resistant to Colletotrichum and resistant to stalk rot. |
| US09884895B2 |
Methods and compositions for chimeric coronavirus spike proteins
The present invention provides compositions and methods comprising a chimeric coronavirus spike protein. |
| US09884889B2 |
Multisignal labeling reagents and processes and uses therefor
Provided are compounds comprising two DNA supramolecular binding molecules covalently joined by a linker group. Also provided are multisignal labeling reagents comprising (i) an oligomer of nucleotides or nucleotide analogs; (ii) a DNA supramolecular binding molecule noncovalently bound to the oligomer; and (iii) a first reactive group or a first partner of a first binding pair covalently bound to the oligomer. Additionally provided are methods of producing multisignal labeling reagents. |
| US09884884B2 |
Compound extracted from husk and fruit stem of xanthoceras sobifolia and its extracting method and use thereof
This invention relates to the compound extracted from husk and fruit stem of Xanthoceras Sobifolia and its extracting method and use thereof. Its chemical structure is as below: A method on its extraction: grinding the husk and fruit stem of Xanthoceras Sobifolia into particles, extracting the particles with solvents, filtrating, reclaiming the solvent and collecting the concentrated solution, passing the collection through macroporous resin, eluting it by solvent, reclaiming the solvent to get the enriched solution, drying the solution to form a brown solid which called total saponins; then dissolving the total saponins in water, extracting by normal butyl alcohol, having the extraction dried to obtain brown powder, chromatographing the powder resolved solution by silica gel column repeatedly, receipting the gradient elution with 100:(35˜60) chloroform:methanol, reclaiming the eluted solution, refining and re-crystallize the left solution, will obtain the white raphide which is the invention compound—Xanthoceraside. It is verified that the compound can be used to make medicine to treat brain diseases and tumors, and to make health food to prevent and cure brain diseases and tumors. |
| US09884883B2 |
Production of rhamnolipid compositions
Provided are organic solvent free methods for obtaining compositions comprising one or more rhamnolipids as well as compositions obtainable from said methods. |
| US09884881B2 |
Chelates of lead (II) and bismuth (III) based on trans-di-N-picolinate tetraazacycloalkanes
The invention relates to a chelate resulting from the complexing of a trans-di-N-picolinate tetraazacycloalkane ligand with a metal cation, said ligand corresponding to formula (A) wherein n is equal to 0 or to 1, R is H or a C1-C18 alkyl radical, and R′ is H or a C1-C18 alkyl radical, said metal cation being a cation of a metal selected from the group consisting of lead (II) and bismuth (III). The invention is applicable in the field of lead trapping and alpha-radioimmunotherapy. |
| US09884875B2 |
Heterocyclic compound and use thereof
Provided is a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof, which has an AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor potentiating action. The compound of the present invention is useful as a prophylactic or therapeutic drug for depression, schizophrenia, Alzheimer's disease or attention deficit hyperactivity disorder (ADHD) and the like. |
| US09884874B2 |
Bromodomain-inhibiting compounds and pharmaceutical composition comprising same for preventing or treating a cancer
Provided is a novel compound having bromodomain and extra terminal domain (BET) protein inhibiting activities, and a pharmaceutical composition comprising the same which can be useful for prevention or treatment of precancerous transformation or cancer. |
| US09884868B2 |
TGF-beta inhibitors
Disclosed are imidazole and thiazole compounds, as well as pharmaceutical compositions and methods of use thereof. One embodiment is a compound having the structure and pharmaceutically acceptable salts, prodrugs and N-oxides thereof (and solvates and hydrates thereof), wherein X, A, Z, R1 and R′ are as described herein. In certain embodiments, a compound disclosed herein inhibits TGF-β, and can be used to treat disease by blocking TGF-β signaling. |
| US09884866B2 |
Immunomodulators and immunomodulator conjugates
The invention provides compounds of formula I: wherein R1-R3, Ra, and Rb have any of the values defined herein, and salts thereof. The compounds have immunomodulatory properties. |
| US09884861B2 |
Compositions useful for treating disorders related to kit
Compounds and compositions useful for treating disorders related to KIT and PDFGR are described herein. |
| US09884860B2 |
Fused pyrroledicarboxamides and their use as pharmaceuticals
The present invention relates in fused pyrroledicarboxamides of the formula (I), in which R1 to R9, X, m and n are as defined in claims. The compounds of the formula (I) are inhibitors of the acid-sensitive potassium channel TASK-1 and suitable for the treatment of TASK-1 channel-mediated diseases such as arrhythmias, in particular atrial arrhythmias like atrial fibrillation or atrial flutter, and respiratory disorders, in particular sleep-related respiratory disorders like sleep apnea, for example. |
| US09884859B2 |
Solid form of pyrazolopyridine compound
A novel crystalline form or amorphous of formula (I) and preparation method thereof are disclosed in present invention, wherein the novel crystalline form is substantially pure crystalline form I, form II, form III or form IV. The novel crystalline forms disclosed herein have good solubility, low hydroscopicity and good stability at high temperature (60° C.), high humidity (RH is 90%±5%) and/or under light (4500+/−500 Lux), which benefit for storage, meet the requirements of drug stability and therefore, making formula (I) suitable for formulation preparation and with high bioavailability. |
| US09884857B2 |
Salts of dasatinib in amorphous form
The present invention primarily relates to salts of Dasatinib, wherein the salts are in amorphous form. The salts described herein preferably comprise a cation of a compound of formula 1 and an anion of a second compound selected from the group consisting of glutaric acid, nicotinic acid and saccharin. The invention is further related to pharmaceutical compositions comprising such a salt. Furthermore, the invention relates to processes for preparing said salts. The invention also relates to several aspects of using said salt or pharmaceutical composition to treat a disease. |
| US09884855B2 |
Salt and crystal forms of PLK-4 inhibitor
A fumarate salt and a maleate salt of compound (I) represented by the following structural formula, as well as their corresponding pharmaceutical compositions, are disclosed. Particular single crystalline forms of 1:1 compound (I) fumarate and 1:1 compound (I) maleate are characterized by a variety of properties and physical measurements. Methods of preparing specific crystalline forms of 1:1 compound (I) fumarate and 1:1 compound (I) maleate are also disclosed. The present invention also provides methods of treating a subject with a cancer. Compound |
| US09884851B2 |
Heterocycle-bisamide inhibitors of scavenger receptor BI
This application describes compounds and methods that can inhibit Scavenger receptor class B, type I (SR-BI) activity, which compounds and methods can be used, for example, to mediate high-density lipoprotein (HDL) lipid uptake and treat hepatitis C viral infections. The compounds have the formula: wherein R1 and R2 are independently H, halogen, cyano, haloalkyl, haloalkyloxy or OMe; or R1 and R2 together are —O—CH2— or —O—CF2—O—; R3 is H, halogen, cyano, haloalkyl or haloalkyloxy; R4 is C1-6alkyl, C3-6cycloalkyl, C3-6cycloalkylmethyl or C3-6cycloheteroalkyl, wherein the heteroatom is N or O; R5 is H or CH3; R6 is C1-6alkyl or C3-6cycloalkyl; and A, B, D and E are each, independently, CH, N, O or S, wherein at least one of A, B, D and E is N, and another of A, B, D and E is N, O or S. |
| US09884845B2 |
Pyrazolyl-ureas as kinase inhibitors
There are provided compounds of formula (I) as defined in the specification, which are p38 MAP kinase inhibitors for use as medicaments for the treatment inter alia of inflammatory diseases. |
| US09884844B2 |
Heterocyclic compounds and methods of use thereof
Provided herein are heterocyclyl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia. |
| US09884840B2 |
Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
Disclosed are beta and gamma-amino isoquinoline amide compounds and substituted benzamide compounds. In particular, the invention provides compounds that affect the function of kinases in a cell and that are useful as therapeutic agents or with therapeutic agents. The compounds of the invention are useful in the treatment of a variety of diseases and conditions including eye diseases such as glaucoma, cardiovascular diseases, and diseases characterized by abnormal growth, such as cancers. The invention further provides compositions containing the beta or gamma-amino isoquinoline amide compounds or substituted benzamide compounds. |
| US09884837B2 |
Method for obtaining phytosterols and/or tocopherols from residue of a distillation of the esters of vegetable oils, preferably from distillation residue from a transesterification of vegetable oils
The invention relates to a method for obtaining and purifying phytosterols and/or tocopherols from distillation residue from a transesterification of vegetable oils, in particular from the vegetable oil-based fatty acid methyl ester production for the field of use of biodiesel (FAME), comprising a first transesterification stage for converting partial glycerides contained in the distillation residue; separating the glycerin phase from a reaction mixture resulting from the first transesterification stage; a second transesterification stage for converting sterol esters contained in the reaction mixture; adding water to the reaction mixture after the second transesterification stage in order to generate a multiphase system; simultaneously or sequentially separating the phases of the multiphase system into a substantially sterol-containing phase; a substantially glycerin- and methanol-containing aqueous phase; and a tocopherol-containing methyl ester phase; and obtaining phytosterols from the sterol-containing phase; and optionally obtaining tocopherols from the tocopherol-containing methyl ester phase. The invention further relates to a method for purifying a phytosterol phase and/or phytosterols. |
| US09884835B2 |
Method for preparing isobenzofuran-1(3H)-one compound
A method for preparing an isobenzofuran-1(3H)-one based compound of the following formula I is provided. R1, R2 and p are defined in the specification. |
| US09884834B2 |
Combined levulinic acid and furfural production from biomass
A process is provided for improved levulinic acid production form biomass, wherein furfural is recovered from vapor flow from the levulinic acid production reactor. The reaction conditions can be chosen to enable good yield for both products and minimization of undesired side products. |
| US09884831B2 |
Azocane and azonane derivatives and methods of treating hepatitis B infections
Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject. |
| US09884830B2 |
Synthesis of tetracyclines and analogues thereof
The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The modular synthesis of tetracyclines and tetracycline analogs described provides an efficient and enantioselective route to a variety of tetracycline analogs and polycyclines previously inaccessible via earlier tetracycline syntheses and semi-synthetic methods. These analogs may be used as anti-microbial agents or anti-proliferative agents in the treatment of diseases of humans or other animals. |
| US09884829B2 |
Process for the preparation of tetraconazole
The present invention relates to a new process for the preparation of Tetraconazole or one of its optically active isomers by means of the fluorination of 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-1-ol. |
| US09884825B2 |
Curcumin analogs and methods of making and using thereof
Compounds having Formula I or II, and methods of making and using thereof, are described herein: |
| US09884823B2 |
Oxime ether acetate compound, preparation method therefor and weeding application thereof
The present invention discloses an oxime ether acetate compound containing a phenylpyridine moiety of formula (I), whose preparation method is as follows: (1) mixing a compound of formula (IV), a compound of formula (V), an alkaline substance A, a palladium catalyst and a solvent A; subjecting the mixture to a reaction at the temperature ranging from −10° C. to the reflux temperature for 0.5-20 hours to obtain a reaction solution A; post-treating the solution A to obtain a compound of formula (II); (2) mixing the compound of formula (II), an alkaline substance B, a phase transfer catalyst and a solvent B; subjecting the mixture to a reaction at the temperature ranging from −10° C. to the reflux temperature for 0.1-2 hours; then adding a compound of formula (III), continuing to react at the temperature ranging from −10° C. to the reflux temperature for 0.5-20 hours to obtain a reaction solution B; and post-treating the solution B to obtain the compound of formula (I). The oxime ether acetate compound containing a phenylpyridine moiety of formula (I) can be used for weeding in crops. |
| US09884815B2 |
PGAM1 inhibitors and methods related thereto
In certain embodiments, the disclosure relates to methods of treating or preventing a PGAM1 mediated condition such as cancer or tumor growth comprising administering an effective amount of PGAM1 inhibitor, for example, an anthracene-9,10-dione derivative to a subject in need thereof. In certain embodiments, the disclosure relates to methods of treating or preventing cancer, such as lung cancer, head and neck cancer, and leukemia, comprising administering a therapeutically effective amount of a pharmaceutical composition comprising a compound disclosed herein or pharmaceutically acceptable salt to a subject in need thereof. |
| US09884814B2 |
Acylguanidines for treating osteoarthritis
The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia. |
| US09884809B2 |
Pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators
Disclosed herein are novel antioxidant inflammation modulators, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds and compositions thereof are also provided. |
| US09884808B2 |
Preparation of an intermediate compound of ioforminol
The present invention relates to a process for the preparation of iodinated X-ray contrast agents and in particular to key intermediates thereof. More particularly, the invention relates to a work-up process for preparation of a compound mixture comprising 1-formylamino-3,5-bis(2,3-bis(formyloxy)propan-1-ylcarbamoyl)-2,4,6-trioodobenzene, a key intermediate in the process for preparing Ioforminol. Further, the invention relates to a process for preparing Ioforminol, a contrast agent useful in X-ray imaging. |
| US09884802B2 |
Substituted aromatic compounds for the treatment pulmonary fibrosis, liver fibrosis, skin fibrosis and cardiac fibrosis
The present invention relates to substituted aromatic compounds for use in prevention or treatment of various fibrotic diseases and conditions in subjects, including pulmonary fibrosis, liver fibrosis, skin fibrosis and cardiac fibrosis, where the compound has the following formula: or a pharmaceutically acceptable salt thereof, wherein A is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(O)—(CH2)n—CH3 or CH(OH)—(CH2)n—CH3 wherein n is 3 or 4; R1 is H, OH or F; R2 is H, OH, F or CH2—OH; R3 is H, OH, F or CH2Ph; R4 is H, OH or F; Q is 1) (CH2)mC(O)OH wherein m is 1 or 2, 2) CH(CH3)C(O)OH, 3) C(CH3)2C(O)OH, 4) CH(F)—C(O)OH, 5) CF2—C(O)OH, or 6) C(O)—C(O)OH. |
| US09884801B2 |
Compounds from antrodia camphorata, method for preparing the same and use thereof
The invention relates to bioactive compounds purified from mycelium of Antrodia camphorata and the manufacturing method thereof. A method for treatment of cancers by administrating an effective amount of the said compounds selected from the group consisting of AC006, AC007, AC009, AC011, AC012, AC007-H1, AC009-H1, and AC012-H1 wherein the cancers is liver cancer, brain cancer, prostate cancer, breast cancer, colorectal cancer, or melanoma. |
| US09884800B2 |
Method of preparing 1,3-butadiene and methyl ethyl ketone from 2,3-butanediol using adiabatic reactor
Disclosed is a method of preparing 1,3-butadiene and methyl ethyl ketone from 2,3-butanediol, including: a) providing a plurality of adiabatic reactors, which include a catalyst bed for dehydrating 2,3-butanediol, without a heat transfer medium, and are connected in series; b) introducing a stream including 2,3-butanediol at a temperature ranging from 200° C. to 400° C. into a first adiabatic reactor among the plurality of adiabatic reactors; c) dehydrating the 2,3-butanediol so as to be converted into 1,3-butadiene and methyl ethyl ketone and discharging a product stream including 1,3-butadiene and methyl ethyl ketone; d) heating the discharged product stream to to 200° C. to 400° C.; and e) introducing the heated product stream into a second adiabatic reactor so that 2,3-butanediol is further dehydrated and converted into 1,3-butadiene and methyl ethyl ketone and then discharging the product stream including 1,3-butadiene and methyl ethyl ketone. |
| US09884799B2 |
Surfactant composition comprising ether compound and catalytic process for manufacturing thereof
Disclosed is a process for preparing at least one ether compound, comprising reacting at least one alcohol (I) with at least one polyol (II) in the presence of a functional polymer [polymer (F)] as a catalyst (X), wherein: the alcohol (I) is represented by the general formula (1): R1-OH (1) wherein R1 is a hydrocarbon group having 1 to 36 carbon atoms, the polyol (II) is represented by the general formula (2): R2-(OH) m (2) wherein R2 represents the skeleton moiety of the polyol and m is an integer of from 2 to 20, and polymer (F) is a polymer comprising recurring units derived from at least one ethylenically unsaturated monomer [monomer (M)] and bearing at least one cation exchange group. Further disclosed is a surfactant composition obtained by said process, and featuring an excellent detergency performance. |
| US09884794B2 |
Dual catalyst system for propylene production
Embodiments of processes for producing propylene utilize a dual catalyst system comprising a mesoporous silica catalyst impregnated with metal oxide and a mordenite framework inverted (MFI) structured silica catalyst downstream of the mesoporous silica catalyst, where the mesoporous silica catalyst includes a pore size distribution of at least 2.5 nm to 40 nm and a total pore volume of at least 0.600 cm3/g, and the MFI structured silica catalyst has a total acidity of 0.001 mmol/g to 0.1 mmol/g. The propylene is produced from the butene stream via metathesis by contacting the mesoporous silica catalyst and subsequent cracking by contacting the MFI structured silica catalyst. |
| US09884792B2 |
Urea-based fertilizer composition and a process thereof
A urea-based slow-release fertilizer composition comprising an alkaline oil component and a urea component, wherein, the alkaline oil component is coated on the urea component, such that the ratio of the alkaline oil component to the urea component is in the range of 0.01:100 to 0.1:100. The fertilizer is cost-effective, easy-to-use, and its quality is maintained during storage and transport. |
| US09884786B2 |
Recycled asphalt concrete with minimized amount of flat and elongated particles, and manufacturing method therefor
The present invention relates to recycled asphalt concrete and a manufacturing method therefor and, more specifically, to recycled and regenerated asphalt concrete and a manufacturing method therefor, which minimizes the amount of flat and elongated particles included in aggregates used as materials for asphalt concrete, thereby increasing the quality of the asphalt concrete to first grade (the amount of the flat and elongated particles is less than 10%) and increasing the durability of the asphalt concrete. |
| US09884784B2 |
Chemically strengthened glass
A chemically strengthened glass having a compressive stress layer formed in a surface layer thereof according to an ion exchange method, in which the glass has a surface roughness (Ra) of 0.20 nm or higher, a hydrogen concentration Y in a region to a depth X from an outermost surface of the glass satisfies the following relational equation (I) at X=from 0.1 to 0.4 (μm), a surface strength F (N) measured by a ball-on-ring test under the following conditions is (F≧1500×t2) relative to a sheet thickness t (mm) of the glass, and a surface of the glass has no polishing flaw: Y=aX+b (I) in which meanings of respective symbols in the equation (I) are as follows: Y: hydrogen concentration (as H2O, mol/L); X: depth from the outermost surface of the glass (μm); a: −0.270 to −0.005; and b: 0.020 to 0.220. |
| US09884783B2 |
Coated glass ceramic plate
A coated glass ceramic cooking plate is provided, which has a multilayer coating on its lower surface. The multilayer coating includes a metallic layer of an alloy including components chromium, iron, nickel, and silicon. The silicon content of the alloy is at least 2 atomic percent. This metallic layer is covered by a barrier layer in form of an oxide of an alloy including components chromium, iron, nickel, and silicon, also with a silicon content of at least 2 atomic percent. The molar content of oxygen of the barrier layer is greater by at least a factor of 10 than that of the metallic layer. |
| US09884775B2 |
Superhydrophilic surface body, fabricating method thereof, and filter for oil and water separation
Disclosed are a superhydrophilic surface body, a fabricating method thereof, and a filter for oil and water separation, including a superhydrophilic surface. The method for fabricating a superhydrophilic surface body includes a first step of forming a polyaniline nanofiber layer on a surface of a base material, a second step of changing the polyaniline nanofiber layer into a completely oxidized pernigraniline base state, a third step of forming a self-assembled monomolecular film having a polymer polymerization initiation functional group on a surface of the polyaniline nanofiber layer, and a fourth step of forming a silica layer on a surface of the self-assembled monomolecular film. In the third step, the polyaniline nanofiber layer is reduced to a leucoemeraldine state. |
| US09884774B1 |
Highly retentive automatically skimmable tank
An automatically skimmable tank for removing oil from water. A water inlet with a 90 degree elbow that is turned sideways and points slight upward causes flow to first impinge on the wall of the tank then flow upward helically around the tank's internal diameter (ID) to maximize retention time so that oil separates from the water. At the tank's upper fluid level, the water flows to the center of the tank, then spirals downward to the bottom and under the incoming fluid flow before exiting via the water outlet. Oil is removed from the tank via an upwardly extending oil outlet riser provided with two horizontal anti-vortex plates. A level transmitter senses the oil-gas and the oil-water interfaces and a programmed PLC activates an oil valve and a low shear oil transfer pump to remove oil from the tank when the oil layer surrounds the anti-vortex plates. |
| US09884768B2 |
Method for manufacturing vertically-growing open carbon nanotube thin film
Disclosed is a method for manufacturing a vertically-growing open carbon nanotube thin film. The method comprises: grinding the surface of a ceramic film by using metallographical sandpaper, performing ultrasonic cleaning by using acetone and performing boiling with water, and performing drying to obtain a ceramic film substrate; dissolving a catalyst ferrocene in a carbon source dimethylbenzene in an ultrasonic manner, and adding a carbon nanotube growth promoting agent thiophene to form a mixed solution; putting the ceramic film substrate in a tubular furnace reactor, introducing nitrogen, and slowly injecting the mixed solution at a constant speed to perform a high-temperature vapor deposition reaction; and further performing plasma etching and nitric acid reflux heating treatment to open closed ends of carbon nanotubes, and removing catalyst particles on the carbon nanotube thin film to obtain the open carbon nanotube thin film that is highly vertically aligned. |
| US09884767B2 |
Zeta positive hydrogenated nanodiamond powder, zetapositive single digit hydrogenated nanodiamond dispersion, and methods for producing the same
The present invention relates to a method for producing zeta positive hydrogenated nanodiamond particles, and to a method for producing zeta positive single digit hydrogenated nanodiamond dispersions. The present invention further relates to zeta positive hydrogenated nanodiamond powder and zeta positive single digit hydrogenated nanodiamond dispersion. |
| US09884766B2 |
Treating particles
A method of treating particles by disaggregating, deagglomerating, exfoliating, cleaning, functionalizing, doping, decorating and/or repairing said particles, in which the particles are subjected to plasma treatment in a treatment chamber containing a plurality of electrodes which project therein and wherein plasma is generated by said electrodes which are moved during the plasma treatment to agitate the particles. |
| US09884763B1 |
Process for group III-V semiconductor nanostructure synthesis and compositions made using same
Methods for producing nanostructures, particularly Group III-V semiconductor nanostructures, are provided. The methods include use of novel Group III and/or Group V precursors, novel surfactants, oxide acceptors, high temperature, and/or stable co-products. Related compositions are also described. Methods and compositions for producing Group III inorganic compounds that can be used as precursors for nanostructure synthesis are provided. Methods for increasing the yield of nanostructures from a synthesis reaction by removal of a vaporous by-product are also described. |
| US09884762B2 |
Silicon nitride substrate and silicon nitride circuit board using the same
A silicon nitride substrate including silicon nitride crystal grains and a grain boundary phase and having a thermal conductivity of 50 W/m·K or more, wherein, in a sectional structure of the silicon nitride substrate, a ratio (T2/T1) of a total length T2 of the grain boundary phase in a thickness direction with respect to a thickness T1 of the silicon nitride substrate is 0.01 to 0.30, and a variation from a dielectric strength mean value when measured by a four-terminal method in which electrodes are brought into contact with a front and a rear surfaces of the substrate is 20% or less. The dielectric strength mean value of the silicon nitride substrate can be 15 kV/rum or more. According to above structure, there can be obtained a silicon nitride substrate and a silicon nitride circuit board using the substrate in which variation in the dielectric strength is decreased. |
| US09884761B2 |
Unit for removing contaminants from hydrogen gas and isotopes of hydrogen gas with features that resist damage from repeating thermal cycles
A hydrogen separator having a first end plate, a second end plate, and a cylindrical support extending from the second end plate. A permeable tube support plate is suspended by the cylindrical support, wherein the second end plate, cylindrical support and permeable tube support plate define a collection chamber. A hydrogen permeable tube is coupled to the permeable tube support plate. A housing surrounds the cylindrical support. An exhaust tube support plate is within the housing and external of the collection chamber, wherein an exhaust chamber is defined between the exhaust tube support plate and the first end plate. |
| US09884760B2 |
Hydrogen generation apparatus
The apparatus includes: a hydrogen generation container provided with a magnesium-based hydride accommodation part accommodating magnesium-based hydride; a reaction water tank storing water or an aqueous solution; the pipes connected to the reaction water tank and the hydrogen generation container; a pump operating to suction water or the aqueous solution from the reaction water tank and then exhaust it through the pipes to the hydrogen generation container; a pressure gauge measuring the pressure in the inside of the hydrogen generation container; and a control unit, on the basis of the pressure value of the pressure gauge, controlling the amount of water caused to flow through the pipes by the pump. |
| US09884756B2 |
MEMS device with getter layer
A MEMS device comprises a first layer (1), a second layer (2) and a third layer (3) sealed together. A mobile structure (7.1, 7.2) in the second layer (2) is defined by openings (8.1, 8.2) in the second layer (2). In the first layer (1), there is at least one first-layer cavity (6.1, 6.2) with an opening towards the mobile structure (7.1, 7.2) of the second layer (2). In the third layer (3), there is at least one third-layer cavity (9) with an opening towards the mobile structure (7.1, 7.2) of the second layer (2). Therefore, the third-layer cavity (9) and the second layer (2) define a space within the MEMS device, A getter layer (10.1, 10.2) arranged on a surface of said space. The getter layer (10.1, 10.2) is preferably arranged on a surface of the second layer (2) and in particular, the getter layer (10.1, 10.2) is arranged on a static part of the second layer (2). Alternatively, the MEMS device has a third-layer cavity (24) with at least two recesses (25.1, 25.2, 25.3) and the getter layer (26.1, 26.2, 26.3) is arranged on a surface of the recesses (25.1, 25.2, 25.3). |
| US09884755B2 |
Rough anti-stiction layer for MEMS device
The present disclosure relates to a MEMS package with a rough metal anti-stiction layer, to improve stiction characteristics, and an associated method of formation. In some embodiments, the MEMS package includes a MEMS IC bonded to a CMOS IC. The CMOS IC has a CMOS substrate and an interconnect structure disposed over the CMOS substrate. The interconnect structure includes a plurality of metal layers disposed within a plurality of dielectric layers. The MEMS IC is bonded to an upper surface of the interconnect structure and, in cooperation with the CMOS IC, enclosing a cavity between the MEMS IC and the CMOS IC. The MEMS IC has a moveable mass arranged in the cavity. The MEMS package further includes an anti-stiction layer disposed on the upper surface of the interconnect structure under the moveable mass. The anti-stiction layer is made of metal and has a rough top surface. |
| US09884752B2 |
Tap, server, pouring member, and attachment/detachment tool
A tap to pour beer foam onto a liquid has a flow path through which the beer foam flows. A folded section and a second extension section of the flow path are curved along a liquid surface of the liquid. |
| US09884750B2 |
Device for remotely commanding a crane
A device for remotely commanding a crane comprises a transmission unit suitable for establishing a communication between the device and a control unit of the crane. The device also includes control panel comprising a plurality of manual control members, each arranged for commanding a specific movement of a plurality of available movements of the crane and the direction of the specific movement. The device may also include a plurality of indicators of the available movements of the crane, each correlated with the specific crane movement commandable by a respective manual control member. |
| US09884746B2 |
Configuration of operating panels of an elevator system
A method and a device configures a floor allocation of at least two operating panels of an elevator system having an elevator car and an elevator control unit in a building having at least two floors, wherein a respective one of the operating panels and an elevator door are located on each floor of the building, wherein a door contact unit is arranged on the elevator door, wherein the door contact unit is opened with the elevator door open, and wherein the elevator car moves vertically between the at least two floors. According to the method and device, the door contact unit is connected with the operating panel on each floor. The elevator car is moved to each floor and the elevator door is opened. The operating panel detects the open door contact unit and allocates the approached floor to the operating panel depending on the position of the elevator car. |
| US09884742B2 |
Elevator safety arrangement having earth fault detection
A safety arrangement of an elevator and a method for monitoring electrical safety in an elevator system is disclosed. The safety arrangement of an elevator includes a motor drive having a main circuit, an accessible conducting part, which is earthed, an insulator, which is adapted to electrically insulate the aforementioned conducting part from the aforementioned main circuit and also a monitoring circuit, which determines an earth fault of the aforementioned main circuit occurring via the conducting part. The monitoring circuit forms a signal indicating the danger of electric shock in the motor drive of the elevator, if the earth fault is diagnosed. |
| US09884740B2 |
Fiber bundle with pieced part, process for producing same, and process for producing carbon fiber
A fiber bundle which has a pieced part formed by jetting a pressurized fluid against a fiber-bundle overlap is formed either by directly superposing the ending part of a fiber bundle composed of many fibers on the beginning part of another fiber bundle composed of many fibers or by superposing the end part and the beginning part on a jointing fiber bundle composed of many fibers, whereby the many fibers of the fiber bundles are interlaced with one another to thereby piece up the fiber bundles. The pieced part comprises an opened-fiber part in which the fibers have been opened and interlaced-fiber parts respectively located on both sides thereof, each interlaced-fiber part being composed of a plurality of constituent interlaced parts located apart in the width direction for the fiber bundle. |
| US09884738B1 |
Wire caddy
A toolbox-size device contains wire spools that are supported by both a cradle and a removable axial spindle. This dual support contributes to solving several problems involved with manual wire deployment devices. Particular object spatial and size relationships can include those of the cradle, spindle, spool diameter, spool hub, arbor-opening diameter, enclosure size, and exit aperture location. This provides a solution to reliably and smoothly deploy electrical wire manually from a hand-carried device. The cradle holds spools generally in place when the axial spindle is removed to add or remove spools. The dual support system allows the use of spools with damaged flanges normally not possible with a cradle-based system. |
| US09884735B2 |
Sheet tray and sheet conveying apparatus
There is provided a sheet tray including: a first tray; a second tray supported by the first tray; and a third tray supported by the second tray. The second tray has a first engaging section engageable with the first tray at a second position; the third tray has a second engaging section contactable with the second tray, in a drawing direction from a first position toward the second position, at a fifth position between a third and a fourth position, and engageable with the second tray at the fourth position. The second engaging section is configured to be elastically deformable to be movable in a releasing direction in which the contact between the second engaging section and the second tray is released. The second and third trays are moved integrally in the drawing direction in a state that the second engaging section makes contact with the second tray. |
| US09884733B1 |
Conveyed bottle guide apparatus and method
Embodiments of the inventive technology disclosed herein may improve efficiency of conveyed bottle apparatus by providing bottle jam prevention guides that may be rotatable, whether freely or in response to a motorized force. Such guides may force downward a bottle that undergone excessive swing in a forward and/or rearward direction, and thus has jammed or is in an incipient jam condition. Advantages may include not only increased efficiency of a conveyed bottle process, but also reduction or even elimination of chatter. |
| US09884728B2 |
Oscillating conveyor and method for operation of an oscillating conveyor
An oscillating conveyor comprising an oscillating rail, at least one electromagnet with a coil, and an armature connected to the oscillating rail, which armature can be moved by activation of the coil to generate an oscillation of the oscillating rail, wherein the coil is part of an oscillator circuit, wherein the oscillator frequency of the oscillator signal of the oscillator circuit depends on the inductance of the coil, which is influenced by the position of the armature relative to the coil, wherein the oscillating conveyor comprises a feedback circuit, which drives the coil by means of a control signal which maps the change over time in the frequency of the oscillator. |
| US09884727B1 |
Diverter with roller pushers
A diverter belt having translatable pushers with article-contacting rollers to push articles across the belt. Cam followers on the pushers follow guides under the belt along an upper carryway run to translate the pushers across the width of the belt along one or more transverse tracks. |
| US09884723B2 |
Spiral conveyor system
A spiral conveyor system with a positive drive system includes a rotating drum with at least one rib that is attached to drum. The rib includes a drive face for engaging a conveyor belt. The height of the rib above of the surface of the drum varies along a length of the drive element. The rib may be directly attached to the drum or may be a part of a drive element attached to the drum. The conveyor belt includes at least one belt surface configured to engage the at least one drive face, such as a protruding tab with a flat surface. |
| US09884718B2 |
Folding, lightweight, hygienic, heavy-duty food shipping container
A reusable, sanitary and folding container includes a base, two folding sidewalls, two folding end walls and latches and hinges. The base includes slots that receive the hinge pins that allow the sidewalls and end walls to fold up and down. These hinge slots are open and provide for water or spray through them during the cleaning process of a container after it has been used. The container is formed of a resilient, but light polyurethane/fiber composite material. |
| US09884710B2 |
Lid member for press-through package and press-through package packing body
A lid member for a press-through package, and a press-through package packing body using the same, includes a lid member which is not to be inadvertently torn, while tablets or capsules as its contents can be removed under a uniform opening strength by a predetermined force or more using fingers. The lid member of the packing body includes a resin film, an adhesive, an aluminum foil, and a thermal adhesive layer, in which tapered through holes are formed in the resin film. The resin film is laminated to the aluminum foil to reinforce the lid member so that the lid member is not to be inadvertently torn. When contents of a container are pushed out using fingers, the lid member is broken starting from the tapered through holes provided in the resin film, and so the contents can be easily taken out. |
| US09884707B2 |
Pop-out constructible utensil
A system and method for co-packaging constructible utensil assemblies with a food container including a utensil layer and a protective laminate layer. The utensil is disposed in the assembly to be easily removed while concurrently being peeled from the protective laminate layer that helps to ensure the cleanliness and sanitary portions of portions of the utensil to contact the foodstuff. |
| US09884704B2 |
Clip-clamp with top lock device and method
A clip-clamp with top lock device for preferably closing and sealing bags and the like. The clip-clamp with top lock device includes a closure assembly including a pair of lever members spatially arranged and facing one another and also including an interconnector extending between the lever members, and further including at least one biased member connected to the lever members for memory retentiveness and to bias the lever members about and seal an opening of a container such as a bag. |
| US09884703B2 |
Container, handle for a container, and handle and container assembly
A container may include a neck including an external surface and at least one handle retention feature with axially lower and upper handle retention surfaces. A handle for a container may include a collar including spaced apart container retention features having axially lower and upper container retention surfaces to cooperate with the corresponding handle retention feature of the container to prevent axial movement of the collar with respect to the container. |
| US09884700B2 |
Dual-use lid and containing assembly comprising the same
A dual-use lid includes a cover. The cover has a protruding segment, an annular wall, and a circular body. The protruding segment is formed on the cover. The annular wall extends from the protruding segment. The circular body is formed on the annular wall. The dual-use lid can be combined with various containers. An annulus is detachably mounted on the cover to form a space for loading food, and users are able to have drink and food at the same time. In addition, the cover and annulus are detachable, such that the cover and annulus can be transported and stored in an increased amount. |
| US09884698B2 |
Thermoplastic container in particular a bottle having a partially prismatic triangular body
Thermoplastic container (1) which after filling and sealing is able to withstand without any substantial deformation to an internal pressure lower than atmospheric pressure, comprising a body (2) with substantially cylindrical upper (3) and lower (4) parts and an intermediate part (5) having a curvilinear triangular cross section and comprising three main faces (6a, 6b, 6c) joined by three edges (7a, 7b, 7c); these edges are rounded, having continuous curvature, joined tangentially to the main faces and have radii of curvature (ra, rb, rc) comprised between approximately 5% and 35% of the largest dimension (D) of the cross section of the lower part (3); the main faces have radii of curvature (Ra, Rb, Rc) greater than the largest dimension (D) of the cross section of the lower part (3). |
| US09884697B2 |
Printer
A printer for label printing includes a cutter to cut a continuous label after printing at a position inside of the surface with respect to the outer case of the printer. A separation sensor is disposed between the cutter and the thermal head. A sheet detection sensor is disposed downstream of the cutter in the feeding direction. The sensors are mounted in two stages on a common circuit board. The circuit board is disposed vertically along the feeding direction of the continuous label within the region where a cover-open button to open an opening and closing cover of the printer is disposed. |
| US09884691B2 |
Helicopter search light
A helicopter search light includes at least one first light source, with the at least one first light source in operation providing a spot light functionality of the helicopter search light, at least one second light source, with the at least one second light source in operation providing a flood light functionality of the helicopter search light, and a switching circuit having a first switching state, with only the at least one first light source being switched on and the helicopter search light providing a pure spot light functionality in the first switching state, and a second switching state, with only the at least one second light source being switched on and the helicopter search light providing a pure flood light functionality in the second switching state. |
| US09884688B2 |
Propulsion system using large scale vortex generators for flow redistribution and supersonic aircraft equipped with the propulsion system
A propulsion system for a supersonic aircraft includes an engine including an engine core and an engine bypass, a compression surface upstream of the engine, a shroud surrounding the engine configured to direct airflow passing over the compression surface towards the engine, and a plurality of vortex generators positioned upstream of the engine. The vortex generators have a height such that when the supersonic aircraft is flown at a predetermined altitude and predetermined speed, the plurality of vortex generators create vortices that propagate partially outside of a boundary layer formed proximate a surface of a supersonic inlet. The vortices cause a high-velocity portion of the airflow to move towards the engine core and a low-velocity portion of the airflow to move towards the engine bypass. The plurality of vortex generators are disposed aft of a terminal shock and have a height greater than the thickness of the boundary layer. |
| US09884684B2 |
In-flight leveling system
The disclosed embodiments relate to an aircraft having an in-flight leveling system for a seat onboard the aircraft that includes a swivel mechanism providing selective rotational movement of the a rear portion of the seat to compensate for an angle of inclination of the aircraft during flight. A locking mechanism is coupled to the swivel mechanism to retain the seat in a first position for use on the ground and a second position for use during flight. An actuator moves the locking mechanism between a locked condition and an unlocked condition permitting the seat to move between the first position to the second position enabling the seat to be substantially level when the aircraft is on the ground and during flight. |
| US09884680B2 |
Elastomeric bearing system motion limiter
The invention relates to a backing plate used for an elastomeric bearing system, the backing plate comprising a plate which defines an at least partial annulus about an axis, a motion limiter and a redundant pivot which extend from the plate so as to respond to a retainer plate disbond. |
| US09884679B2 |
Aircraft steering system controller
A controller for an aircraft steering system, the controller being configured to receive a steering input representative of a desired direction of travel of a steerable nose landing gear, and to receive one or more force-based inputs representative of lateral forces acting upon the nose landing gear, wherein the controller is adapted to automatically adjust the steering input based upon the force-based input(s) so as to output an adjusted steering command for a steering actuator of the nose landing gear. |
| US09884678B2 |
Landing gear drive system flexible interface
Known autonomous taxi systems for aircraft include a rigid connection between the aircraft wheel and a gear which is used to drive it. Such arrangements have been found to suffer from the problem that wheel deformation modes cause unacceptable wear and/or stresses within the drive system and/or wheel. The present invention thus proposes a drive system for an aircraft landing gear, the drive system comprising: a pinion gear; a drive shaft arranged to rotate the pinion gear about a drive axis; a driven gear arranged to mesh with the pinion gear to be rotatable by the pinion gear, the driven gear being connectable to a wheel of the landing gear to be capable of rotating the wheel about a wheel axis; and a flexible interface. The flexible interface comprises a plurality of driven gear coupling members, each driven gear coupling member having a first connection portion attached to the driven gear, a second connection portion adapted to be attached to the wheel at an offset distance from the wheel axis, and a joint between the first connection portion and the second connection portion, the joint permitting relative movement between the first connection portion and the second connection portion. |
| US09884672B1 |
Electrolytic protection system for stern drive marine motors having a cavitation plate
An electrolytic protection system for stern drive marine motors having a cavitation plae, said system comprising an adaptors fixedly secured to said cavitation plate, and an anode mateable with said adopter. |
| US09884667B1 |
Advanced water control storage frame system for marine vessels
A water control storage frame system for at least one storage compartment is formed in a boat having a deck. The system includes a frame structure rising above the deck of the boat and defining an upper peripheral opening of the at least one storage compartment. The frame structure is provided with an external structure facing away from the at least one storage compartment and configured for preventing water collecting on the deck from entering the at least one storage compartment and directing water from the deck into a drainage area. An internal structure is integrally formed with the external structure, and is configured as a peripheral track structure for receiving and retaining storage items at various locations along the peripheral track structure within the at least one storage compartment. |
| US09884665B2 |
Bicycle pedal with magnetic member
A bicycle pedal assembly includes a pedal having an axle rotatably extending therethrough to be connected to a crank. At least one magnetic member is connected to the outside of the pedal and attracted to an object such as a wall. The bicycle is positioned at an upright position when the least one magnetic member is attracted to a wall with a proper feature that is magnetically attracted by the at least one magnetic member on the pedal. |
| US09884664B2 |
Methods and apparatus for selective stiffness of vehicle suspension
A suspension assembly including a core member; and a skin member bonded on said core member. The skin member having a higher strength than the core member. |
| US09884660B2 |
Composite panel edge treatments and joints and cargo body having same
A cargo body includes sidewalls constructed of pairs of panels secured together at respective joints. Each panel is an assembled panel having a core, an interior skin, and an exterior skin. In some cases, each joint is formed to include overlapping edge portions of first and second ones of the adjacent pair of panels. Each of the overlapping edge portions has a thickness less than 20 percent of a total panel thickness of the corresponding one of the adjacent pair of panels such that the joint formed thereby defines a recess between co-facing edge portions of the first and second ones of the adjacent pair of panels. A profile insert defining a longitudinal channel is positioned in the recess defined by the overlapping edge portions at each joint. Each joint is secured by fixedly attaching the profile insert to the overlapping edge portions. |
| US09884656B2 |
Mud flap lifter
The present invention relates to a mud flap lifting system for raising and lowering a pair of mud flaps connected to a rear portion of a vehicle and suspended behind corresponding rear wheels of the vehicle, which is particularly beneficial for use on dump trucks. The lifting system raises the rear mud flaps to a safe position when the truck is reversing or on unstable soil or is dumping its load. The mud flaps may thereafter be lowered via an associated control switch in the cab of the truck so that the truck may travel from the job site. |
| US09884655B1 |
Structure for mounting vehicle heat exchanger
Disclosed herein is a structure for mounting a heat exchanger in a vehicle. The structure includes a shroud, and a mount supporting a supported portion and allowing vertical vibrations of the supported portion with respect to each side of the shroud in a vehicle width direction. The supported portion is provided on each side of the heat exchanger in the vehicle width direction. The mount body of the mount is mounted in a mounting portion located higher than a fixed portion on the side of the shroud in the vehicle width direction. The fixed portion is fixed to a body member of the vehicle. A receiver supporting a lower surface of the mount body serves as the mounting portion. A fixing bracket for fixing the mount body to the side of the shroud is provided in front of or behind the mount body of the mount in the vehicle. |
| US09884653B2 |
B pillar with partial strength characteristics
A B pillar for a motor vehicle is produced as a hot-stamped and press-hardened component composed of a hardenable steel alloy, wherein a lower length section extends over less than 40% of the length (L) of the B pillar in a longitudinal direction and at least regionally has different strength values in relation to an upper length section, which B pillar is, in the lower length section, in at least one cross section, mutually different strengths are formed, and in the lower length section, a soft material structure is formed regionally. |
| US09884651B2 |
Vehicle side portion structure
A vehicle side portion structure is provided that can suppress or prevent separation at a joined portion between members at a time of a vehicle side collision. At a pillar outer reinforcement, a reinforcement upper and a reinforcement lower are joined at a joined portion by spot welding or the like. A hinge reinforcement is, in a state of spanning over this joined portion, joined to the reinforcement upper and the reinforcement lower. Therefore, when tensile force is applied to the pillar outer reinforcement, shearing force that acts on the joined portion can be reduced by reaction force obtained from the hinge reinforcement. Due thereto, at a time of a vehicle side collision, separation at the joined portion can be suppressed or prevented. |
| US09884650B2 |
Vehicle body structure
The invention relates to a vehicle body structure, with at least one hollow profile beam (1) that extends in the direction (x) of the lengthwise extension and with a hollow profile (7) whose height (Δz1; Δz2) between two opposite profile walls (17) varies along the direction (x) of the lengthwise extension, and in this hollow profile (7) at least one dividing element (23) is arranged in order to reinforce the hollow profile beam (1) in a crosswise direction (y). According to the invention, the dividing element (23) consists of two separate sheet metal parts (33, 35) which are each firmly attached to the opposite profile walls (17) and which are firmly joined together at a shared connection point (A). |
| US09884647B2 |
Utility vehicle
A vehicle includes a frame assembly extending along a longitudinal axis of the vehicle and including a rear frame portion. The rear frame portion includes at least one upstanding member, at least one longitudinal member, and at least one coupling member coupled to the at least one upstanding member and the at least one longitudinal member. The vehicle also includes at least one front ground-engaging member supporting the frame assembly, at least one rear ground-engaging member supporting the frame assembly, a drivetrain assembly operably coupled to the front and rear ground-engaging member, and a rear suspension assembly. The rear suspension assembly includes at least one radius rod operably coupled to the at least one rear ground-engaging member and angled less than 90° relative to the at least one longitudinal member. |
| US09884645B2 |
Lane change control system
When an object detected by a lane marking/object detection section has been determined to be an object present in an adjacent lane change target lane or in the vicinity of the adjacent lane, lane change control is performed to reduce a predetermined maximum lateral acceleration Aymax′ or maximum lateral velocity Vymax′ according to the lane width Lob of the adjacent lane. |
| US09884643B2 |
Friction compensation control apparatus and method of MDPS system
A friction compensation control apparatus of a motor driven power steering (MDPS) system may include: a damping control unit configured to detect a damping torque of the MDPS system; and a friction compensation control module configured to detect a friction compensation torque using a column torque, a motor speed, and a vehicle speed, and adjust the detected friction compensation torque according to the magnitude of the damping torque. |
| US09884640B2 |
Foldable stroller
A foldable stroller includes a frame and a locking component. The frame includes a handle, a front foot, a rear foot, and a carrier support. An upper end of the front foot is pivoted to the handle. An upper end of the rear foot is pivoted to the handle. The carrier support includes at least one connecting rod. An end of the at least one connecting rod is pivoted to the front foot, and the other end of the at least one connecting rod is pivoted to the rear foot. The locking component is installed between the rear foot and the handle. The locking component locks rotation of the rear foot relative to the handle when the foldable stroller is unfolded. Due to aforementioned structure, the foldable stroller is not only reliable in operation but also has a smaller occupied space after being folded. |
| US09884633B2 |
Zip line rail system
The zip line rail system can be connected to a challenge course, a zip line, a zip track system, or any combination thereof. The zip line rail system of the present invention can have two rails that a member slide's two wheels rollably engage with, and the zip line rail system can be configured in any of a variety of directions. |
| US09884632B2 |
Personal vehicle management
Among other things, one or more techniques and/or systems are provided for personalized vehicle management. A current location of a vehicle may be received. A route of the vehicle may be determined based upon a trip library and/or the current location. The trip library may correspond to routes traveled by the user above a travel frequency threshold. A route segment (e.g., a portion of the route that the vehicle will travel within a threshold duration) may be identified. A route segment characteristic (e.g., a weather characteristic, a physical characteristic, a traffic characteristic, etc.) of the route segment may be determined. The route segment characteristic may be provided to a driver assistance component of the vehicle. The driver assistance component may be instructed to alter functionality of the vehicle using a vehicle operational parameter derived from the route segment characteristic. |
| US09884630B1 |
Autonomous vehicle performance optimization system
An autonomous vehicle (AV) performance optimization system can receive vehicle data from human-driven vehicles, and determine a set of performance metrics for determining AV performance in relation to human performance based on the vehicle data. Thereafter, the system can receive AV data from AVs operating or configured for operation throughout a given region. Based on the AV data, the system can determine a performance score for each of the set of performance metrics for the AV. |
| US09884627B1 |
Device and method for adjusting vehicle fuel efficiency based on an altered vehicle surface area
A device and method for adjusting vehicle fuel efficiency to responsive to an altered vehicle surface area are disclosed. An operation of the method receives vehicle surface data, which indicates a transition from a first vehicle drag coefficient value relating to a vehicle surface area to a second vehicle drag coefficient value relating to the altered vehicle surface area. A second plurality of powertrain parameter values associated with the second vehicle drag coefficient value are determined, and the method operates to transmit the second plurality of powertrain parameter values for adjusting of the vehicle fuel efficiency. |
| US09884626B2 |
Vehicle control system and method
Embodiments of the present invention provide a control system for a motor vehicle, the system being operable in an automatic mode selection condition in which the system is configured to select automatically an appropriate system operating mode and to assume operation in said system operating mode, wherein when operating in the automatic mode selection condition the system is configured to prevent selection of a prescribed one or more operating modes if it is determined that the vehicle is towing a load. |
| US09884623B2 |
Method for image-based vehicle localization
A method for image-based vehicle localization includes measuring, at a vehicle, a position and a heading of the vehicle; capturing, at an image capture system of the vehicle, road surface image data of a road surface; processing the road surface image data to correct for distortion in the road surface image data due to pitch and roll of the vehicle; performing feature detection on the processed road surface image data to detect lane markers on the road surface; generating a local map based on the detected lane markers; wherein generating the local map comprises identifying a lane demarcated by the detected lane markers; and controlling the vehicle according to the local map. |
| US09884621B2 |
Autonomous parking controller and method based on ambient conditions relating to a vehicle parking location
Devices and methods in an autonomous parking controller for a vehicle are disclosed. When the vehicle is located at a parking location, the method determines whether the parking location includes a parking restriction. When the parking location includes the parking restriction, the example method compares the parking restriction with at least one restriction threshold. When the parking restriction compares unfavorably with the at least one restriction threshold, the example method, while at the parking location, monitors for a change in at least one of a plurality of ambient conditions relative to the vehicle. When the example method detects the change, the vehicle is autonomously relocated to another location to alleviate the active obstruction. |
| US09884620B2 |
Automated parking system
A method for determining the position of a motor vehicle on a traffic area of a parking facility includes the steps of scanning a camera image of the traffic area including the motor vehicle, determining a position of the motor vehicle based on the camera image, scanning the motor vehicle with the aid of a stationary sensor on the traffic area, and validating or correcting the determined position based on the scanning with the aid of the stationary sensor. The stationary sensor is configured like a parking facility sensor, which is configured to determine the presence of a motor vehicle parked in a parking space of the parking facility, the parking space being reachable with the aid of the motor vehicle via the traffic area. |
| US09884614B2 |
Control system for vehicle
A control system is for a vehicle (Ve), and the control system comprises an electronic control unit (18). The electronic control unit (18) is configured to (i) produce differential rotation by controlling a rotational speed of either a first clutch member (24) or a second clutch member (25) of a selectable one-way clutch (17) by a motor (2), and (ii) execute the following processes in an order of (1.) to (4.) in the case where the electronic control unit (18) switches the selectable one-way clutch (17) from a disengaged state to a engaged state: (1.) controlling the motor (2) such that the differential rotation becomes the negative differential rotation; (2.) switching the selectable one-way clutch (17) from a second state to a first state; (3.) controlling the motor (2) such that the differential rotation becomes the positive differential rotation; and (4.) engaging a part of a strut with a part of the second clutch member (25). |
| US09884611B2 |
Delegating control of a vehicle
An identification of a vehicle is received. An identification of a first user to receive delegation of control of the vehicle is received. Authentication information for the first user for the vehicle is determined. A request to authenticate the first user for delegation of control of the vehicle to the first user is received. The request to authenticate includes at least the authentication information for the first user is determined. Responsive to the determination, control of the vehicle is delegated to the first user. |
| US09884605B2 |
Force-limiting device for a seat belt system
A force-limiting device (4) for a seat belt device which has at least two parts (5, 11, 15) controlled with a frequency-dependent, defined movement, wherein the parts (5, 11,15) moving relative to one another feature gearings (8, 10, 18, 19) engaging into each other and the frequency-dependent, controlled movement occurs such that at least one of the parts (5, 11, 15) executes a feed movement (V) with respect to the other part (5, 11,15) with an undulating motion (Q) perpendicular to the feed movement (V) in which the gearings (8, 10, 18, 19) alternatingly engage and disengage, by means of which a force limited belt extraction is facilitated. Wherein means are provided with which the required force for movement of the parts (5, 11, 15) toward one another can be automatically increased after a preset belt extraction length. |
| US09884604B2 |
Child safety harness assembly
A child safety harness assembly for securing a child in a vehicle includes a first strap that has a midsection. The midsection is curved, such that opposing side sections of the strap extend in substantial parallelism from the midsection. Each of a pair of second straps is coupled to and extends between the opposing side sections. The second straps are substantially evenly spaced between the midsection and opposing ends of the first strap. A third strap has a first endpoint that is coupled to the midsection equally distant from the opposing ends of the first strap. Each of a set of three couplers is coupled singly to the opposing ends and the third strap. The second straps and the third strap are length adjustable. The couplers are configured to couple to anchors of the vehicle to couple the child to the vehicle. |
| US09884603B2 |
Steering wheel airbag apparatus
A steering wheel airbag apparatus may include: a mounting plate seated on a wheel armature, and having a guide pipe formed therein; a cover coupled to the mounting plate; a moving contact module movably installed in the guide pipe, pressurized and moved by the cover, and connected to a positive electrode; and an elastic contact portion coupled to the guide pipe, connected to a negative electrode while supported by the negatively charged wheel armature, and connected to the moving contact module as the moving contact module is moved. |
| US09884602B2 |
Airbag control unit, power network, and method for controlling a voltage network in a motor vehicle
An airbag control device, wherein the airbag control device generates at least one actuation signal for an actuation time as a function of at least one sensor signal, wherein the airbag control device can maintain the at least one actuation signal for a holding time, wherein the airbag control device has at least one non-volatile memory in which the generation of the at least one actuation signal can be stored, wherein the airbag control device, when the at least one actuation signal is generated, stores a status signal in the at least one non-volatile memory or in a further non-volatile memory, wherein the status signal is deleted again if the at least one actuation signal was generated for longer than a storage time. Also disclosed is a voltage network in a motor vehicle and to a method for actuating a voltage network. |
| US09884598B2 |
Bumper device for a vehicle
A bumper device for a vehicle is arranged on one of a front side and a rear side of a vehicle cabin to extend in a vehicle width direction. The bumper device for a vehicle includes: a tubular portion, which is made of metal and integrally formed so as to have a tubular shape extending in the vehicle width direction; and a reinforcing member, which is formed so as to have a plate-like shape extending in the vehicle width direction along an inner surface of the tubular portion. A foamed resin charged into the tubular portion is foamed to be increased in volume, to thereby fix the reinforcing member inside the tubular portion. |
| US09884597B2 |
Multi-strip beam-forming apparatus, method, and beam
A bumper reinforcement beam includes sheets pre-formed to have integral features and to have a final beam shape with non-radiused corners and optimal impact properties, including beams with constant or varied cross-sectional shapes, and beams made of steel, aluminum, or hybrid materials or combinations of material, all of which allow minimization of weight. The non-radiused corners offer excellent impact strength and properties. Beam impact properties can be improved or locally tuned for particular functional requirements by material selection, or by adding an internal reinforcement on an inside center of the front wall, or by localized annealing of the welds to minimize stress risers, or by localized features and shapes. The sheets can be welded using welding processes that provide low heat-affected-zones around the weld or by localized annealing, thus minimizing any adverse effect of welding. |
| US09884596B2 |
Apparatus and method for preventing a vehicle from running out of fuel
An apparatus for use with a motor vehicle to simulate fuel loss to encourage early refueling to prevent stranding. The apparatus may cause stumbling and hesitation by interrupting various engine management systems to simulate low fuel in the tank by cutting either spark or fuel momentarily or applying the brakes. |
| US09884594B1 |
Utility rack system and attachments
A storage system includes a utility rack having a base frame with a plurality of cross members extending across the base frame and an accessory. The accessory includes at least one attachment device for attaching to at least one of the cross members. The attachment device includes a cross member retainer configured to partially retain a cross member, a hinged brace configured to move between an open position rotated away from the cross member retainer and a closed position rotate towards the cross member retainer and configured to press against the cross member, and a latch configured to lock the hinged brace in the closed position and maintain a pressure of the hinged brace against the cross member. |
| US09884581B1 |
Adjustable lever load binder
A lever load binder which provides fine adjustments for accommodation of the length of the tiedown chain without twisting of the tiedown chain or binder, increased efficiency of use, and improved safety. |
| US09884580B2 |
Ratchet tie down incorporating a standard interface plate connection
A ratchet assembly for a vehicle bed includes a ratchet mechanism having a ratchet frame and an interface anchor. An operable strap extends and retracts from the ratchet mechanism. An interface plate having a securing recess is disposed within a vehicle-bed sidewall that selectively receives the interface anchor. An interface bracket extends from at least one sidewall and selectively engages the interface anchor to couple the ratchet mechanism with the interface bracket. The interface bracket includes a rotating mechanism operable between an engaged position and a secured position. When the interface bracket is in the engaged position in the interface plate, the rotating mechanism is free of engagement with a securing recess and the interface bracket is operable within the interface plate. When the interface bracket is in the secured position in the interface plate, the interface bracket is free of movement within the interface plate. |
| US09884570B2 |
Adjustable seat assembly
A seat assembly is provided with a seat cushion, and a seat back. Sensors are operably connected to the seat cushion and the seat back to detect a seating position of an occupant. An actuator is operably connected to the seat cushion and the seat back for adjustment of a plurality of settings of the seat assembly. An interactive user interface permits manual adjustment of the actuator. A controller is in electrical communication with the plurality of sensors, the at least one actuator, and the user interface. The controller is configured to receive seating position data input indicative of a manually selected seating position. Detection data is received from the plurality of sensors, and compared to the manually selected seating position to determine if the occupant is seated evenly. The at least one actuator adjusts an occupant seating position to the manually selected seating position. |
| US09884569B2 |
Brake control device for a vehicle and method for operating at least one electric drive motor for a vehicle
A brake control device is provided for a vehicle having an activation device, with the aid of which, at least under consideration of at least one brake demand signal provided by an on-board sensor and/or control device, at least one first control signal may be output to at least one electric drive motor of the vehicle, with which the at least one electric drive motor is controllable into a motor mode, in which a generator braking torque which is unequal to zero may be exerted on at least one wheel of the vehicle by the at least one electric drive motor, the at least one electric drive motor being controllable with the aid of the at least one first control signal into at least one overload operating mode as the motor mode, in which the generator braking torque which is unequal to zero may be exerted on the at least one wheel. A method is also provided for operating at least one electric drive motor for a vehicle. |
| US09884566B2 |
Straddled electric vehicle
A battery with increased capacity is provided in a straddled electric vehicle including a drive unit provided on a rear arm for supporting a rear wheel such that the rear wheel is rotatable. A power supply unit is located in a vehicle body frame to supply electric power to the drive unit. The drive unit includes a motor that overlaps the rear wheel in a side view of the vehicle. The power supply unit includes a battery and a controller. The controller supplies electric power stored in the battery to the drive unit. The vehicle body frame includes a head pipe and a pivot shaft. The pivot shaft supports the rear arm such that it is swingable. The power supply unit is located between the head pipe and pivot shaft in a side view of the vehicle. |
| US09884561B2 |
Charging system
A system includes a vehicle with a charge socket and a contactor switching unit, and a charger for charging an electrical energy accumulator of the vehicle at a vehicle-external AC power system. The charger is a vehicle-external charger device. The charger is a portable charger. The charger has a DC-DC converter, and includes first and second charging cables. The first charging cable has an AC power system plug, and the second charging cable has a charge plug. |
| US09884560B2 |
Method and system for controlling on-board battery charger of vehicle
A system and method for controlling an on-board battery charger of an eco-friendly vehicle are provided. In the method, when instantaneous interruption of electric power occurs in an AC input power source, a DC-DC controller adjusts an output current instruction to be limited to the minimum charging power, and a power factor corrector (PFC) controller outputs a voltage instruction to a first capacitor (DC link capacitor) connected to an output terminal of the PFC controller to be updated to zero (0) or an actual value of the DC link capacitor. When the AC input power source is then restored, the PFC controller outputs the voltage instruction to the first capacitor to be increased to the existing voltage instruction with a predetermined slope, to smoothly perform the charging operation of the on-board battery charger without pause. |
| US09884558B2 |
Range extending charging system for an electric vehicle
In an electric vehicle having a primary battery powered source of energy with a primary electric motor driven and connected to one or more ground engagement wheels of the electric vehicle, has a device utilizing a sprocket and chain for collecting energy from the inner rim edge of the rear wheel of the electric vehicle. This sprocket mechanism device collects this energy then transfers that energy to a plurality of alternators on mounted framework such as in the trunk compartment by way of a chain. The alternators with their sitting pilot voltages, then transfer it by electrically conductive cables to the battery. |
| US09884557B2 |
Apparatus and method of preventing over-discharge of vehicle battery
An apparatus of preventing over-discharge of a battery for a vehicle includes a voltage sensor for sensing a voltage of the battery, a relay for preventing the over-discharge of the battery, a power state sensor for sensing an ignition on state, and a controller for outputting a warning message when the voltage of the battery becomes a first threshold value in the ignition on state and for turning off the relay after transmitting shut-off commands to the respective electronic control units (ECUs) through a vehicle network when the voltage of the battery becomes a second threshold value. |
| US09884555B2 |
Vehicle control system
A vehicle having a wading sensor may include a control unit adapted to implement an alternative or modified vehicle control strategy during wading. The wading strategy may change many vehicle functions, alone or in combination, and may be further responsive to depth of wading. |
| US09884547B1 |
Manual transmission with electric motor input
A vehicle powertrain includes an engine having a drive shaft. A manual transmission includes an input shaft drivingly connected to the drive shaft and includes a plurality of input gears. A main shaft includes a plurality of driven gears engaged with the input gears and including an output gear that is engaged with a differential. An electric motor is connected through a planetary gear set to a transfer gear on the main shaft. |
| US09884544B2 |
Underbody unit for a motor vehicle
An underbody unit (10) for reinforcing a motor vehicle body of a motor vehicle has a floor body (12) that is connectable to the motor vehicle body for dissipating loads of the motor vehicle body. The floor body (12) has an upper side (32) for supporting battery cell units (18) of a traction battery for driving the motor vehicle purely electrically and at least one cooling channel (26) for cooling the upper side (32). The floor body (12) and the underbody unit (10) form a supporting plate of a battery housing and can: support the battery cells (18) of the traction battery, form an armor plating to protect the battery cells (18) and define a heat exchanger that can actively and/or passively cool the battery cells (18) with the aid of the cooling channel (26). |
| US09884543B2 |
Automobile back-door structure
A back door structure for an automobile is provided with a back door frame including a window frame, a window located at a vehicle outer side of the window frame, and a blind including a cover that covers a gap between the window and the window frame. The blind joins the window with the back door frame. |
| US09884542B2 |
Vertical sealing arrangement between doors without side pillars
A vertical sealing arrangement to be used between doors of utility motor vehicles of various types, such as pickups, trucks, SUVs, sedans, hatchbacks and the like with front and rear doors without the side pillar, the so-called B pillar, is formed by two moldings, the top collector and the bottom discharger, which are interconnected by an extruded profile having at least one hollow longitudinal cavity the lumen of which interconnects the inside volume of the collector to the inside volume of the discharger, thus defining a flow path for water and dust deposited on the upper part of the vehicle down to the lower part of the vehicle. |
| US09884537B2 |
Vehicle having an electric heating device
A vehicle has an electric heating device which in operation reaches a temperature of more than 50° C., and includes a flat perforated decorative layer which is disposed on a front face of the heating device. Because of the perforation of the decorative layer, the heating device can radiate infrared radiation through holes provided in the decorative layer directly into a passenger compartment of the vehicle. The vehicle also has a reflector layer which is disposed on a rear face of the heating device facing away from the front face and is provided in order to reflect infrared radiation emitted by the heating device in the direction of the passenger compartment. |
| US09884533B2 |
Autonomous control damper
A damper system for a vehicle comprises an electrically adjustable hydraulic shock absorber and a damper control module. The damper control module is disposed with and coupled to with the shock absorber. The damper control module determines a target damping state of the shock absorber based on data received from a plurality of sensors. Furthermore, the damper control module controls the shock absorber, such that the shock absorber operates at the target damping state. |
| US09884532B2 |
Suspension control device for vehicle
A suspension control device includes an actuator configured to change an up/down stroke of a suspension, a front sensor, and a control device configured to estimate a displacement in a vertical direction of a road surface based on a detection result of the front sensor, thereby controlling the actuator. When the control device determines that a step portion in which a wheel comes into contact with two points of the road surface viewed in a direction along a rotational axis of the wheel exists ahead of a vehicle, the control device controls a force generated by the actuator so that, when the wheel comes into contact with the two points, the wheel rolls about the point without substantially pressing the point toward the travel direction of the vehicle. |
| US09884530B2 |
Dual engine air and land multimodal vehicle
An air and land multimodal vehicle comprises a frame, a propeller engine attached to a first location of the frame supplying power and torque to a propeller, a ground engine attached to a second location of the frame supplying power and torque to one or more ground traction elements, and a flexible wing releasably connectable to the frame, wherein the propeller engine is vertically and horizontally spaced from the ground engine and the ground engine extends at least six inches below a base of the frame. |
| US09884525B2 |
Method for installing a monitoring device in a tyre for vehicle wheels
A method for installing a monitoring device in a tire for vehicle wheels, includes: providing a monitoring device including: an electronic unit; a connecting member having an upper structure and a lower structure that, in cooperation, define a housing for the electronic unit, the lower structure including two base portions mutually separated by a separation region, each of the base portions having a respective base surface associable with an inner surface of a tire. The method further includes providing a positioning device including two separate active portions, each having a main surface in the shape of which matches that of a respective portion of an outer surface of the monitoring device, the separate active portions being adapted to cooperate with at least the base portions; associating the positioning device with the monitoring device to keep the monitoring device in an installation condition in which the base portions are maintained at a given mutual distance by the active portions; fastening the base portions to the inner surface of the tire; and removing the positioning device. |
| US09884522B2 |
Central tire inflation system and method
A central tire inflation system for a tire. The system includes one or more pneumatic control valves for controlling inflation of a respective tire. A first compressed air source is provided for supplying compressed air to inflate the tire. A second compressed air source is provided for supplying compressed air to control the at one or more pneumatic control valves. A control means is provided for controlling the supply of compressed air from the second compressed air source to generate a pneumatic control signal to control the one or more pneumatic control valves. The first compressed air source can be a compressor configured to provide compressed air to inflate the tires. The second compressed air source can form part of an air suspension system. |
| US09884520B2 |
Pneumatic tire
A pneumatic tire having a designated orientation for mounting to a vehicle includes a tread, sidewalls, beads including bead cores, respectively, and a carcass including a carcass ply. Each bead includes a rubber apex, an outer bead and an inner bead, the rubber apex includes an outer apex portion and an inner apex portion, the outer apex portion includes a first outer apex portion positioned inward from the carcass ply in the axial direction and a second outer apex portion positioned outward from the carcass ply in the axial direction, the inner apex portion includes a first inner apex portion positioned inward from the carcass ply in the axial direction and a second inner apex portion positioned outward from the carcass ply in the axial direction, and the second outer apex portion has height which is greater than height of the second inner apex portion in the radial direction. |
| US09884515B2 |
Tire
A tire, including a circular tire frame formed of a resin material, the resin material including a resin composition in which at least one thermoplastic resin selected from the group consisting of a polyamide-based thermoplastic resin, a polyester-based thermoplastic resin, and a polyolefin-based thermoplastic resin, and at least one elastomer selected from the group consisting of a diene-based rubber, a vinyl acetate copolymer, a polyurethane, an ethylene propylene rubber, and any modified product thereof have been dynamically crosslinked. |
| US09884514B2 |
Floor brake assembly for an article of furniture
A floor brake assembly for an article of furniture includes a base adapted to be affixed to an article of furniture, a plunger having a brake pad at a plunger first end and movable between a first position where the brake pad engages a floor and a second position where the brake pad is free of the floor, a pivot arm rotatably mounted to the base, a first activation arm pivotally mounted to the base, and a second activation arm pivotally mounted to the base. The pivot arm is rotated between a braking position and an unbraking position to cause the plunger to move between the first and second positions by way of the first and second activation arms. |
| US09884507B2 |
Searchable binder with inductive address code transfer
A binder management system having a cabinet with shelves for removable storage of searchable binders. Each binder has a body with front and rear covers and a spine. Inside the body is a binder mechanism for removably retaining sheet media. Each binder has a planar receiving antenna mounted on the spine in a plane parallel to the lower margin of the spine or mounted on one of the covers in a plane parallel to the cover plane Each binder has a binder identification circuit coupled to the receiving antenna and to an LED mounted on the binder spine in a location visible when the binder rests on a shelf. When a binder identification signal from a host computer is detected by the receiving antenna it is transferred to the binder identification circuit. If the signal matches an address code stored in the binder identification circuit, the LED is activated to aid the user in finding the binder. Transmitting antennae are mounted on the shelves to broadcast the binder identification signals to the receiving antenna mounted in the binder. An LED and an optional audible indicator are mounted on the shelves to further aid the user in finding the sought binder. |
| US09884505B2 |
Recording medium and process for producing same
A recording medium having a base and an ink receiving layer containing an inorganic particle and at least one compound selected from a compound represented by the following formula (I) and a compound represented by the following formula (II): |
| US09884500B2 |
Tape cartridge
A tape cartridge which contains a tape-shaped printing medium and is to be mounted on a mounting section of a tape printer includes a tape roll around which the printing medium is wound and a core shaft portion that rotatably supports the tape roll. An inner circumferential portion of the core shaft includes a shape forming a first fitting portion which is fitted to a pedestal portion erectly disposed on the mounting section when the tape cartridge is mounted on the mounting section, and a second fitting portion which is fitted to a first convex portion erectly disposed on the pedestal portion when the tape cartridge is mounted on the mounting section. |
| US09884498B2 |
Tape printing device and tape printing system
A tape printing device includes a cartridge loading section where a tape cartridge having a platen roller and a portion to be guided is loaded in an unloadable manner; two recess portions in which fingers for gripping the tape cartridge are inserted; a platen support shaft inserted in the platen roller; and a guide pin inserted in the portion to be guided. The guide pin is situated on a side opposite to the platen support shaft across an imaginary line connecting the two recess portions and is arranged at a site where a distance from the recess portion at a position farther from the first insertion shaft, of the two recess portions, is shorter than a distance from the recess portion at a position closer to the platen support shaft. |
| US09884496B1 |
System for detecting contamination on decurler rollers in aqueous ink printers
A decurler is configured for use in an aqueous inkjet printer to monitor ink contamination of the indent roller in the decurler and generate a signal that maintenance is required prior to the printer beginning to produce wrinkled media sheets by the ink contamination on the indent roller. A reflective sensor is mounted on a shaft for bidirectional movement to sweep the length of the indent roller and generate electrical signals indicative of the presence or absence of contamination on the indent roller. The controller receiving signals from the reflective sensor compares the signals from the reflective sensor to a predetermined threshold prior to commencing monitoring of the indent roller to determine positions where the sensor is opposite the indent roller and positons where the sensor is opposite a frame in the printer. |
| US09884493B2 |
Image recording apparatus
An image recording apparatus includes: a recording section configured to record an image on a sheet conveyed in a conveyance direction in a conveyance route; and an abutment member having a plurality of abutment portions which are arranged apart from each other in a width direction orthogonal to the conveyance direction so that the plurality of abutment portions abut against the sheet convened in the conveyance route respectively, and a connecting portion connecting adjacent abutment portions among the plurality of abutment portions. The connecting portion twists so as to rotate with the width direction as a rotation axis, under a condition that the plurality of abutment portions abuts against the sheet. |
| US09884478B2 |
Can decorator machine, ink station assembly therefor, and can decorating method employing same
An ink station assembly is for a can decorator machine structured to decorate a plurality of cans. The ink station assembly includes a first oscillator roll and a second oscillator roll each having a longitudinal axis and being structured to oscillate back and forth along the longitudinal axis, a printing plate cylinder including a printing plate, and only one single form roll cooperating with the printing plate cylinder to apply a supply of ink to the printing plate, the single form roll cooperating with the first oscillator roll and the second oscillator roll. |
| US09884472B2 |
Reduced complexity automatic fiber placement apparatus and method
A method of forming a composite layup on a substrate comprises: moving an automatic fiber placement head over the substrate; using the fiber placement head to lay down multiple, parallel strips of composite tape on the substrate, including staggering the start of at least certain of the tape strips so as to form a contour pattern; and, cutting the ends of all of the tape strips using a single cut. |
| US09884470B2 |
Laminate structure including a primer coating therein
A laminate structure is provided which includes a first polymeric substrate laminated to a second polymeric substrate. A primer coating comprising the reaction product of polyethyleneimine and formaldehyde is included on the surface of the first polymeric substrate which is subsequently printed with an ink or toner image prior to lamination to the second polymeric substrate. The primer coating provides good toner and/or ink adhesion to the polymeric substrate. The primer coating also provides improved bond strength upon lamination of the first and second polymeric substrates as well as providing water resistance to the laminate structure. |
| US09884466B2 |
Fiber-reinforced resin member
Since a continuous fiber of a fiber-reinforced resin member includes an axial fiber aligned in the axial direction and an axially right-angled fiber aligned at right angles to the axial direction, and the density of the axially right-angled fiber of a first layer on the outer side of the corner part is made higher than the density of the axially right-angled fiber of a second layer on the inner side of the corner part, when an axial load is input and the fiber-reinforced resin member breaks, the axially right-angled fiber disposed at high density in the outside first layer of the corner part is actively stretched and breaks, thereby enabling a large energy-absorbing effect to be exhibited. Moreover, the fiber-reinforced resin member has a simple structure in which merely the density of the axially right-angled fiber in its interior is changed, thereby minimizing any increase in the production cost. |
| US09884465B2 |
Dunnage conversion machine and method with downstream feed monitor
A dunnage conversion machine provides an improved electronic monitoring and control system for detecting and resolving many jamming conditions before they require significant operator intervention. The machine includes a conversion assembly with a feeding device that feeds the sheet stock material through the machine, and a sensing device downstream of the feeding device to monitor movement of the stock material downstream of the feeding device and to output a corresponding signal. A controller controls operation of the feeding device in response to the signal from the sensing device. The controller uses the signal to detect a potential jam condition and controls the feeding device to prevent or minimize the occurrence or severity of the jam condition, thereby minimizing the amount and degree of required operator intervention. |
| US09884451B2 |
Method of using ultrasonic vibration to secure body tissue
A suture and a suture retainer are positioned relative to body tissue. Ultrasonic vibratory energy is utilized to heat the suture retainer and effect a bonding of portions of the suture retainer to each other and/or to the suture. Portions of the body tissue may be pressed into linear apposition with each other and held in place by cooperation between the suture and the suture retainer. The suture retainer may include one or more portions between which the suture extends. The suture retainer may include sections which have surface areas which are bonded together. If desired, the suture may be wrapped around one of the sections of the suture retainer. The suture retainer may be formed with a recess in which the suture is received. If desired, the suture retainer may be omitted and the sections of the suture bonded to each other. |
| US09884449B2 |
Three-dimensional printed part removal using an interlaced platen
A method of manufacturing a three-dimensional object operates a platen configured to facilitate the release of objects produced by a three-dimensional object printer. The method includes moving a first plate and a second plate to form a platen, the first plate having a plurality of parallel members and the second plate having a plurality of parallel members, the first plate and the second plate being moved to interlock the plurality of parallel members of the first plate with the plurality of parallel members of the second plate to form the platen, at least one of the first plate and the second plate being independently movable. At least one of the first plate and second plate is moved to release a three-dimensional object formed by the printer from the platen. |
| US09884442B2 |
Preform injection molding device
An injection molding device including a middle flow channel which forms an intermediate layer of a preform which is subject to biaxial stretch blow molding. The middle flow channel s segmented into a predetermined number of flow sub-channels by vertical blocking rib piece(s). Side wall's upstream portions of the vertical blocking rib piece are formed as angled surfaces whose distance from each other decreases from the downstream side to the upstream side, and/or, an end portion of the vertical blocking rib piece that is located on the downstream side is tucked in at least one of the inner flow channel and the outer flow channel. |
| US09884440B2 |
Roll fed flotation/impingement air ovens and related thermoforming systems for corrugation-free heating and expanding of gas impregnated thermoplastic webs
Disclosed herein are roll fed air heated flotation ovens and related thermoforming systems, assemblies, and machines that enable the corrugation-free expansion of a gas impregnated thermoplastic web passing through an oven chamber (without use of a pin-chain assembly), as well as to related methods. In an embodiment, a gas impregnated thermoplastic web is conveyed and expanded through an elongated air heated oven chamber, wherein the elongated oven chamber includes a plurality of downwardly directed heated air nozzles positioned at regular intervals along and within the upper portion of the oven chamber, and a plurality of upwardly directed heated air nozzles positioned at regular intervals along and within the lower portion of the oven chamber, but staggered apart from the downwardly directed heated air nozzles such that the gas impregnated thermoplastic material web undulates in an up and down wavelike fashion, thereby minimizing sagging, bagging, puckering, and/or buckling of the web. |
| US09884436B2 |
Method for making a curved sandwich structure using a reconfigurable UV source mounting element
A process for fabricating a curved vehicle impact sandwich beam including a micro-truss structure. The method includes positioning a mold in contact with a curved bottom facesheet so that the mold and the bottom facesheet define a reservoir. The reservoir is filled with a liquid photo-polymer resin and a mask is positioned over the reservoir. A series of UV light sources are provided on a mounting member relative to the mask and the mounting member is flexed to conform to the shape of the bottom facesheet. Light from UV sources shines through apertures in the mask to cure and form polymerized struts in the reservoir to define the micro-truss structure formed to the facesheet. |
| US09884435B2 |
Casting cup assembly for forming an ophthalmic device
Disclosed in this specification is a casting cup assembly comprising frontcurve and basecurve molds which of which includes a ring that circumscribes the respective concave and convex mold surface. When the casting cup is assembled, the rings align and minimize de-centering and tilting of the concave and convex mold surfaces which, in turn, reduces edge defects. |
| US09884425B2 |
Robot, robot control device, and robotic system
A robot includes an arm, and the arm is controlled using an offset of a reference point of a tool, the tool being attached to the arm, the offset being set based on a first state, in which a first image, in which the reference point is located at a control point of an image, can be taken by a imaging section, and a second state, in which a second image, in which the tool is rotated around a rotational axis passing through a position of the reference point in the state in which the reference point is located at the control point, can be taken by the imaging section, and controlled based on a third image, which is taken by the imaging section, and in which the control point is shifted from the reference point, in a process of a transition from the first state to the second state. |
| US09884424B2 |
Display control apparatus and method for same
A display control apparatus operable to display an operation of a robot comprising: an obtaining unit configured to obtain measurement information of a processing target that includes at least one of the robot and a target that the robot operates; an emphasizing unit configured to generate emphasized display information that emphasizes a feature of a portion of the processing target, based on the measurement information; a composition unit configured to generate composite display information in which the emphasized display information and non-emphasized display information other than the emphasized display information are composed; and an output unit configured to output the composite display information to a display unit. |
| US09884423B2 |
Autonomous robot auto-docking and energy management systems and methods
A method for energy management in a robotic device includes providing a base station for mating with the robotic device, determining a quantity of energy stored in an energy storage unit of the robotic device, and performing a predetermined task based at least in part on the quantity of energy stored. Also disclosed are systems for emitting avoidance signals to prevent inadvertent contact between the robot and the base station, and systems for emitting homing signals to allow the robotic device to accurately dock with the base station. |
| US09884420B2 |
Robotic turntable assembly
A robotic turntable assembly for servicing an item includes a support station for supporting the item on a first support region of the support station. The first support region is movable between an operational zone and a non-operational zone. The robotic turntable assembly includes an operational assembly that services the item when the first support region supports the item and the first support region is within the operational zone. The operational assembly engages the support station and moves the first support region between the operational zone and the non-operational zone. |
| US09884418B2 |
Disassembly tool kit for replacing vehicular decorative plates
A disassembly tool kit for replacing vehicular decorative plates comprises a handle including a handheld end and a handle-side engagement end far away from the handheld end, and at least one replaceable tool each including a tool-side engagement end corresponding to the handle-side engagement end and a working end far away from the tool-side engagement end. The handle-side engagement end includes a first fixing element and a first locking element. The working end includes a decorative-plate disassembly element. The tool-side engagement end includes a second fixing element corresponding to the first fixing element for a press-fit engagement and a second locking element corresponding to the first locking element for a locking effect. The user may select an appropriate replaceable tool according to the decorative plate or strip, which is to be disassembled, and install the replaceable tool in the handle. |
| US09884417B2 |
Lightweight mop and mop bucket used therewith
The present disclosure relates to a portable mop and a mop bucket used with the portably mop. The portable mop includes a mop rod (1). The mop rod (1) is provided with a steering mechanism (5). The steering mechanism (5) includes a sleeve nut (6), a locking thread sleeve (7) and a hinged ladder rotating shaft (8). A hinge plane (10) is arranged at the upper end of the hinged ladder rotating shaft (8). The mop bucket includes an integrated squeezing and brushing device is formed by the connection of the squeezing roller pair and the brush body by virtue of a combined support; the combined support comprises a left and a right side baffles; and the brush body is fixedly connected with the squeezing roller pair through connecting screw rods to form a whole. |
| US09884416B2 |
Devices including power tools with non-binding linear slides and associated methods
Devices with non-binding linear slides include: (a) a device body and first and second spaced apart linear rails held in the device body; (b) first and second spaced apart (rail) pathways held in cooperating alignment with the rails in the body, a respective one engaged with a respective one of the first and second linear rails that define spaced apart contact points; and (c) a translating actuation (e.g., input) member held by the body in communication with the rails. The actuation (e.g., input) member has a configuration that can generate off-center loads associated with forces applied at different positions of the actuation (e.g., input) member. Only one pathway and rail pair guides linear movement for the first and second force positions to thereby inhibit frictional binding. |
| US09884415B2 |
Automotive hood spring installer/remover tool
An apparatus to install or remove tension coil springs from spring seat. Apparatus spans beyond the length of a tension coil spring allowing connection to spring ends with a loop and or hook on a threaded shaft. Applying a turning force to threaded shaft will stretch spring to a longer length allowing removal of spring from spring seat. A turning force in opposite direction retracts spring to shorter length allowing installation of spring to spring seat. |
| US09884411B2 |
Tool structure
A tool structure includes a base, a first retaining member, a connecting rod, a second retaining member, and a threaded rod. The first retaining member is received in the base. The second retaining member is received in the connecting rod and engages the first retaining member so that the connecting rod is limited in the slot of the base. Thus, the connecting rod is rotated relative to the base to adjust different angles between the connecting rod and the base. In addition, the connecting rod has a first mounting hole and a second mounting hole so that the connecting rod is available for two kinds of screwdriver tips with different sizes. |
| US09884409B2 |
Pipe wrench
A pipe wrench includes a fixed jaw with alternatively located first recesses and first driving faces defined in the inner side thereof. A pivotal member is pivotably connected to the fixed jaw and a resilient member is biased between the fixed jaw and the pivotal member. The pivotal member has alternatively located third recesses and second driving faces. A hexagonal space is defined between the first and second driving faces. The end portion of the pivotal member is inserted into a second recess defined in the inner side of the fixed jaw. The object is clamped in the hexagonal space, and the pivotal member can be pivoted away from the fixed jaw. The pipe wrench is able to quickly clamp and dismounted from the object. |
| US09884408B1 |
Pool pump-trap wrench systems
A pool pump-trap wrench system including a pool pump-trap wrench assembly. The pool pump-trap wrench assembly including, a handle-frame, a top-unit, and two offset-lower-levers. The handle-frame, the a top-unit, and the two offset-lower-levers are structured and arranged in combination to provide a user with a device useful for affixing to a wide variety of pool pump-trap covers for cleaning and maintaining a the pool pump-trap. The handle-frame includes a handle and a frame. The frame includes a frame-opening, at least one frontward-notch, and at least one rearward-notch. Included is the top unit including a front-member, a rear-member, and a center-section; with the center-section including a body and a body-opening. The handle-frame includes the handle; the frame includes the frame-opening, the at least one frontward-notch, and the at least one rearward-notch; where the top-unit includes the front-member, the rear-member. |
| US09884407B2 |
Shot processing machine
Provided is a shot peening device with which recovered projection material and foreign bodies can be more precisely separated while inhibiting an increase in the size of the device. The shot peening device is provided with: a projector which projects projection material onto a workpiece (W); recovery mechanisms which recover the projection material projected by the projector; and a wind power sorting mechanism in which recovered projection material is allowed to fall freely while an upward air current is applied to the recovered projection material, and foreign bodies included in the recovered projection material are separated from the recovered projection material. |
| US09884406B2 |
High-pressure waterjet cutting head systems, components and related methods
A waterjet cutting head assembly is provided which includes an orifice unit to generate a high-pressure waterjet, a nozzle body and a nozzle component coupled to the nozzle body with the orifice unit positioned therebetween. The nozzle component may include a waterjet passage, at least one jet alteration passage and at least one environment control passage. The jet alteration passage may intersect with the waterjet passage to enable selective alteration of the waterjet during operation via the introduction of a secondary fluid or application of a vacuum. The environment control passage may include one or more downstream portions aligned relative to the fluid jet passage so that gas passed through the environment control passage during operation is directed to impinge on an exposed surface of a workpiece at or adjacent to a location where the waterjet is cutting the workpiece. Other high-pressure waterjet cutting systems, components and related methods are also provided. |
| US09884401B2 |
Elastic membrane and substrate holding apparatus
An elastic membrane is used in a substrate holding apparatus for holding a substrate such as a semiconductor wafer and pressing the substrate against a polishing surface. The elastic membrane includes a plurality of concentrically circumferential walls configured to define a plurality of pressurizing areas for pressing the substrate. The pressurizing areas includes a central pressurizing area located at a central part of the elastic membrane, an annular edge pressurizing area located at the outermost part of the elastic membrane, and a plurality of intermediate pressurizing areas located between the central pressurizing area and the annular edge pressurizing area. The area width of at least one of the intermediate pressurizing areas is set in a range to allow a polishing rate responsive width not to vary even when the area width is varied. |
| US09884399B2 |
Hinge mechanism for small optics and related methods
A hinge assembly for a deployable mirror includes a base, a mirror segment base coupled to the base, a mirror segment coupled to the mirror segment base by two bearings, and at least one linear actuator secured to the base and capable of adjusting the mirror segment. Other embodiments of the hinge assembly are further disclosed. |
| US09884394B2 |
Solenoid control methods for dual flow HVAC systems
Provided are a method and apparatus for reducing a refrigerant pressure difference within an HVAC system having a controller, one or more compressors, and at least two paths of refrigerant piping comprising alternative paths for refrigerant flow through the HVAC system. A valve is coupled to each refrigerant piping path for permitting, or preventing, refrigerant flow through each of the alternate paths of refrigerant piping. The controller may open at least one valve for a defined period of time in response to a triggering input to allow a refrigerant pressure difference within the HVAC system to dissipate across the opened valve. |
| US09884392B2 |
Laser welding apparatus and laser welding method
Provided is a laser welding apparatus that performs welding by irradiating a laser beam onto a welded part, the laser welding apparatus including: a shielding gas supply unit that supplies a shielding gas to the welded part; a gas feed rate controlling unit that controls a flow rate of the shielding gas; a light intensity measurement unit that measures a light intensity of plasma light emitted from the welded part; and a rate-of-change calculation unit that calculates a rate of change of the light intensity measured by the light intensity measurement unit. The gas feed rate controlling unit controls, according to the calculated rate of change of the light intensity, the flow rate of the shielding gas supplied to the welded part. |
| US09884383B2 |
Wire-cut electrical discharge machining machine in which position of liquid level of machining fluid is adjusted at time of automatic wire threading
A wire-cut EDM machine in which the position of the liquid level of machining fluid is adjusted at the time of automatic wire threading includes a shape information acquisition unit for acquiring information on the shape of an object to be machined, a wire-threading position information acquisition unit for acquiring information on a wire-threading position of a wire electrode based on relative positions of upper and lower wire guides, and a liquid level position adjustment unit for acquiring the height of the object to be machined in the vicinity of the wire-threading position based on the information on the shape of the object to be machined and adjusting the position of the liquid level of the machining fluid at the time of automatic wire threading. |
| US09884375B2 |
Method and device for producing a cavity in a stator of an eccentric screw pump
In a method for producing a cavity (14) in a stator of an eccentric screw pump, material is removed in the interior of a stator blank (10) by means of a tool (11). In order that very long stators can be produced in one production operation, the tool (11) performs a rotational motion through a first shaft (12) and an eccentric motion around a second shaft (13), during which the stator blank (10) and the tool (11) are moved toward each other. A device for performing the method comprises (a) a bearing shaft (3) that can be coupled with its drive end to a first drive and that is rotatable around its longitudinal axis by means of the first drive; (b) a drive shaft (4) that can be coupled with its drive end to a second drive and is arranged in a borehole of the bearing shaft (3) and is rotatable around its longitudinal axis by means of the second drive form-fitting and relative to the bearing shaft (3), and (c) a machining tool (5), which is rotationally fixed connected to the machining end of the drive shaft (4) that can be inserted into the cavity and can be driven rotatably via the drive shaft (4) around the longitudinal axis of the drive shaft (4). The longitudinal axis of the drive shaft (4) intersects the longitudinal axis of the bearing shaft (3) at a point or is arranged askew to the longitudinal axis of the bearing shaft (3). |
| US09884373B2 |
Hole saw with interchangeable cutting blades
A hole saw having a blade portion separable into two parts which when separated form a base portion and a tip portion. The base and the tip have correspondingly shaped apertures and lugs that co-operate together to hold the blade tip in place. A locking means further assists in ensuring that the blade tip remains locked to the base and includes a sliding latch that engages an aperture in the blade and the base and is itself locked in place to thereby lock the blade to the base. An intermediate portion also allows for the hole saw to drill through different depths. |
| US09884372B2 |
Method and system for defining the position of a fastener with a peen mark
A method and system are provided to position and drill an opening for a fastener through one or more workpieces. In the context of a method, a peen mark is formed on a workpiece at a location at which the opening is to be drilled. The method also includes utilizing a robotic vision system to identify the peen mark on the workpiece and thereafter drilling the opening configured to receive the fastener at the location designated by the peen mark. In the context of a system, the system includes a dot peen marking system configured to form a peen mark on a workpiece at a location at which the opening is to be drilled. The system also includes a robot comprising a vision system configured to identify the peen mark on the workpiece and a drilling machine configured to drill the opening at the location designated by the peen mark. |
| US09884371B2 |
Multi-step drilling apparatus and methods utilizing air flow sensing control
Apparatus and methods for performing and controlling the sequence of steps in a multi-step machining process utilizing a plurality of drilling units, where each drilling unit is configured to perform at least one step of the multi-step machining process. Air pressure sensors in each drilling unit measure air pressures at the surface of a workpiece where the cutting tool of the drilling unit is engaged, which measured air pressures indicate air flow at the surface. These air flows in turn indicate the state of the machining at the surface of the workpiece, and based on the state of the machining, a machine control system will determine whether a drilling unit can perform its particular machining operation in the proper sequence on the workpiece. |
| US09884364B2 |
Molding apparatus
A die casting machine has a clamping device and an injection device. The clamping device has a fixed die plate which holds a fixed die, a movable die plate which holds a moving die, an electrically operated die opening and closing-use driving device which moves the movable die plate in a die opening and closing direction, and a clamping cylinder which generates a clamping force. The injection device has a sleeve, a plunger which capable of sliding in the sleeve, an electrically operated injection-use driving device which drives the plunger at least at the time of low speed injection, and an injection cylinder which drives the plunger at least at the time of high speed injection. |
| US09884357B2 |
Metal separator molding device and method for molding metal separator
A metal separator molding device is provided for molding a metal separator by press-molding a thin plate-shaped base material by using a first die and a second die capable of moving towards and away from each other. The metal separator molding device has a first heating part for heating the thin plate-shaped base material, a channel-processing part for pressing the thin plate-shaped base material heated by the first heating part using the first die and the second die to form channels through which a medium flows, and a controller for controlling the operations of the first heating part and the channel-processing part. |
| US09884355B2 |
Manufacturing method of seamless metal pipe, mandrel mill, and auxiliary tool
A manufacturing method of a seamless metal pipe includes: preparing a plurality of mandrel bars in which lengths of work portions which come into contact with a hollow shell during elongating are different from one another; selecting a mandrel bar including a work portion having a length corresponding to the number of stands used in thickness reduction, among the plurality of mandrel bars; inserting the mandrel bar selected in the selecting into the hollow shell; and performing the elongating on the hollow shell into which the mandrel bar is inserted. Moreover, in the elongating, outer diameter reduction is performed by one of a preceding-stage stand group and a succeeding-stage stand group and the thickness reduction is performed by the other of the preceding-stage stand group and the succeeding-stage stand group, or the thickness reduction is performed by both of the preceding-stage stand group and the succeeding-stage stand group. |
| US09884353B2 |
Drain cleaner
A drain cleaner includes a handle assembly having a grip, a motor positioned within the handle assembly, and an actuator supported by the handle assembly adjacent the grip. The actuator is electrically coupled to the motor and operable to selectively energize the motor. The drain cleaner also includes a shroud fixed to and extending forwardly from the handle assembly. The shroud includes a closed end adjacent the handle assembly. The drain cleaner further includes a drum assembly rotatably coupled to the handle assembly and positioned within the shroud. The drum assembly is operable to be rotated by the motor relative to the handle assembly and the shroud. The drain cleaner also includes a flexible cable stored within the drum assembly. The flexible cable is configured to be extended out of the drum assembly and into a drain. |
| US09884343B2 |
Closure of cooling holes with a filling agent
A method for filling cooling holes in a component of a gas turbine engine is disclosed. The component may include a plurality of first cooling holes extending through the wall of the component. The method may comprise the steps of exposing the outer surface of the component, filling the plurality of first cooling holes with a polyimide, curing the polyimide to block the passage of cooling fluid through the plurality of first cooling holes, and applying a thermal bather coating over the outer surface of the component. The method may further include the step of installing a second plurality of cooling holes in the wall of the component wherein the plurality of second cooling holes penetrate the thermal barrier coating and the wall of the component and allow cooling fluid to pass therethrough. |
| US09884342B2 |
Techniques for marking product housings
Techniques or processes for providing markings on products are disclosed. The markings provided on products can be textual and/or graphic. The techniques or processes can provide high resolution markings on surfaces that are flat or curved. In one embodiment, the products have housings and the markings are to be provided on the housings. For example, the housing for a particular product can include an outer housing surface and the markings can be provided on the outer housing surface. The markings can be formed using a ultra-violet (UV) curable material that can be selectively cured on a surface (e.g., housing surface) in places where markings, namely text and/or graphics, are to be provided. |
| US09884340B2 |
Deposition apparatus and method with cooler
A deposition apparatus and method for depositing an organic material includes an effusion cell, a guide rail, and a cooling channel. The effusion cell extends in a first direction. The guide rail is below the effusion cell and extends in a second direction. The cooling channel is below an upper surface of the guide rail and extends in the second direction. |
| US09884338B2 |
Modular tire spraying system
A modular tire spraying system includes a downdraft spray booth for receiving a tire, a fluid delivery system disposed in the spray booth, a robot for transporting the tire to the spray booth, and a platform on which each of the spray booth, the fluid delivery system, and the robot is disposed. The fluid delivery system includes at least one spray gun for delivering a coating to the tire. |
| US09884336B2 |
Multifunctional dispensing device for dispensing fluid compositions
A dispensing device is selectively operable in a first mode of operation and a second mode of operation. The device comprises a base and a refill removably connectable with the base. The base comprises a first dispensing system and a first actuator communicably connected with the first dispensing system. The refill comprises a reservoir having a sidewall and an orifice. The first dispensing system is in fluid communication with the refill in the first mode of operation and the refill is disconnected from the base in the second mode of operation. |
| US09884335B2 |
Hand held dispenser
A manually operated pump (1) for dispensing a fluid substance in which the movable element (16) of the delivery valve has an at least partially conical surface adapted to be coupled with a corresponding surface of a seat of the delivery valve, in a manner so as to be fit therein due to the action of the spring (10) that loads the movable element (16). |
| US09884334B2 |
Variable-volume dispenser for accurately dispensing of an adjusted amount of liquid
The present invention relates to a bottle top dispenser. According to an embodiment, the dispenser comprises a swayable selector for convenient and rapid volume adjustment by a user. The dispenser further comprises a second selector for analogous volume adjustment, wherein a user may use one of the two selectors according to preferences. The dispenser further preferably comprises two different graduations for assisting a user in the rapid identification of a specific volume when adjusting the volume. The dispenser relates to further advantageous embodiments. |
| US09884332B2 |
Spraying apparatus having water and air intakes
A spraying apparatus includes a convergence chamber having a large end and a small end; at least two water inlets provided in the large end of the convergence chamber, each water inlet having a central axis and the at least two water inlets being arranged at convergent angles to each other so that the central axes converge in free space within the convergence chamber; at least one air intake provided in the convergence chamber between the large end and the small end; and a rectifier opening including a throat provided at the small end of the convergence chamber; and a spraying opening, the rectifier opening having a cross-sectional area that continuously increases outwardly from the throat to the spraying opening, and the throat having a cross-sectional area that is one to three times greater than that of a total cross-sectional area of the at least two water inlets. |
| US09884324B2 |
Advanced solid waste sorting systems and methods
The method and systems efficiently extract recyclable materials from a mixed solid waste stream. The methods and systems use sizing, density and dimensional separation to produce intermediate waste streams that are enriched in particular recyclable materials. The recyclable materials can then be efficiently sorted from the individual intermediate streams using mechanized sorting equipment. |
| US09884322B2 |
Stand for microplates
A laboratory stand for a microplate comprises a base (2), at least one post (3, 4) extending upwardly from the base, a shelf (5) located above the base and supported by the at least one post, and means for adjusting the height of the shelf in relation to the base. The shelf (5) comprises a rear portion (9) which is substantially horizontal and a front portion (10), which is inclined downwards away from the horizontal, which is adapted to retain at least one microplate. The laboratory stand improves pipetting ergonomics. |
| US09884321B2 |
Laboratory device
It is problematic that modern classrooms are often not so flexibly usable that said classrooms are suitable for lecture-style teaching and also for natural-science teaching with practical instructional content. Therefore, the invention relates to a laboratory device (1), comprising a cabinet (10), which has an internal cabinet space (11), wherein a laboratory bench (20) is supported at the cabinet (10) in such a way that the laboratory bench can be pivoted about an axis of rotation (A), and wherein the laboratory bench (20) is positioned in the cabinet space (11) in a first pivot position (P1) about the pivot axis (A) and is arranged at least partially outside of the cabinet space (11) in a second pivot position (P2) about the axis of rotation (A). |
| US09884320B2 |
System and method for detecting biomarker
A system for detecting one or more biomarkers is provided, the system comprising: an inlet region for receiving a sample; a channel connected with the inlet region, wherein the channel allows the sample to move along thereof; multiple functional zones arranged along the channel in a designated distribution; and a driving mechanism to force the sample to move along the channel. |
| US09884319B2 |
Integrated pipette tip devices
Disclosed herein are fluid handling devices that include integrated card and pipette tip devices, for use with multichannel liquid dispensing devices. |
| US09884318B2 |
Multi-axis, multi-purpose robotics automation and quality adaptive additive manufacturing
A system and method for using multi-axis deposition tool heads on a machine such as a three dimensional fabrication device like a 3D Printer, for novel automation and additive manufacturing techniques which offer increased output product quality and fabrication speed by introducing a novel cartridge and deposition systems and techniques. The system allows a plurality of materials, some reacted or mixed by the device, to be extruded through a deposition head, which may adaptively (and automatically) change shape and lumen size to accommodate different path widths and shapes. The cartridge system may employ pellets which may be comprised of a plurality of materials and/or colors. |
| US09884316B2 |
Mononuclear ruthenium complex and organic synthesis reaction using same
A neutral or cationic mononuclear ruthenium divalent complex represented by formula (1) can actualize exceptional catalytic activity in at least one reaction among a hydrosilylation reaction, hydrogenation reaction, and carbonyl compound reduction reaction. (In the formula, R1-R6 each independently represent a hydrogen atom or an alkyl group, aryl group, aralkyl group, organooxy group, monoorganoamino group, diorganoamino group, monoorganophosphino group, diorganophosphino group, monoorganosilyl group, diorganosilyl group, triorganosilyl group, or organothio group optionally substituted by X; at least one pair comprising any of R1-R3 and any of R4-R6 together represents a crosslinkable substituent; X represents a halogen atom, organooxy group, monoorganoamino group, diorganoamino group, or organothio group; L each independently represent a two-electron ligand other than CO and thiourea ligands; two L may bond to each other; and m represents an integer of 3 or 4.) |
| US09884307B2 |
Mof-type layered coordination polymers of manganese, method of their preparation, modification and use thereof
The invention solves the problem of the development of microporous layered MOF-type manganese materials based on isonicotinate anions, their synthesis and modification with selected ionic substances and application associated with the adsorption of the molecules and the construction of solid superionic conductors. |
| US09884299B2 |
Process for the preparation of water-in-oil and oil-in-water nanoemulsions
Process for the preparation of a water-in-oil or oil-in-water nanoemulsion wherein the dispersed phase is distributed in the dispersing phase in the form of droplets having a diameter ranging from 1 to 500 nm, comprising: 1) the preparation of a homogeneous water/oil blend (I) characterized by an interface tension lower than 1 mN/m, comprising water in an amount of 30 to 70% by weight, at least two surface-active agents having a different HLB, selected from non-ionic, anionic, polymeric surface-active agents, said surface-active agents being present in such a quantity as to make the blend homogeneous; 2) the dilution of the blend (I) in a dispersing phase consisting of oil or water with the addition of a surface-active agent, selected from non-ionic, anionic, polymeric surface-active agents, the quantity of the dispersing phase and surface-active agent being such as to obtain a nanoemulsion having a HLB different from that of the blend (I). |
| US09884297B2 |
Device for metering a reagent by dissolution in a liquid flow
The invention relates to a metering device (D) for metering a reagent by dissolution in a liquid flow, characterized in that it comprises a plurality of parts: —a fixed base (200) grouping together said enclosure and a liquid inlet, means for bringing the liquid into contact with the reagent roller (G) and liquid outlet means, —one or more cartridges (300) forming a separate detachable volume grouping together said reagent magazine, means for forming at least one liquid jet directed substantially radially towards the roller (G) to be dissolved, and means for supporting the roller (G), said cartridge (300) coming to be associated with said base (200) which is preformed with at least one area for receiving said cartridge (300) for the purpose of dissolving the reagent. |
| US09884296B2 |
Composite membrane utilized in membrane distillation
A composite membrane includes a hydrophobic porous membrane and a high water content hydrogel layer disposed on the surface of the hydrophobic porous membrane facing the hot end. The surface active agents contained in the wastewater at the hot end are blocked by the high water content hydrogel layer, thus the problem of pore wetting of the hydrophobic porous membrane can be prevented. Therefore, the membrane distillation technique can be utilized for processing wastewater containing surface active agents. |
| US09884295B2 |
Membrane bioreactor system using reciprocating membrane
The present invention relates to membrane bioreactor (“MBR”) system that includes a mechanical membrane reciprocation system to reduce or eliminate membrane fouling. The disclosed MBR system can be operated with higher flux and lower fouling than MBR systems using air scouring. Furthermore the system can remove nitrogen and phosphorous with one RAS and one or no internal recirculation line. The membrane can be reciprocated by a low RPM motor connected to a pulley via belt to rotate rotor to convert rotational motion into reciprocating motion of membrane. Various mechanical means can also be employed to create the reciprocating motion. |
| US09884288B2 |
Treatment process of gas containing zero-valent mercury and mercury separation system
A treatment process of a gas containing zero-valent mercury and a mercury separation system, by which the amount of an iodine compound used can be reduced when the zero-valent mercury is separated from the gas containing the zero-valent mercury by using the iodine compound. The process has a step of oxidizing the zero-valent mercury contained in the gas with a first liquid phase containing an alkali metal iodide, thereby obtaining a second liquid phase containing a divalent mercury ion and an iodide ion; a step of separating the divalent mercury ion as mercury sulfide by adjusting the pH of the second liquid phase; and a step of circulating a third liquid phase which is obtained by separating the mercury sulfide in the mercury separation step to use the third liquid phase as the first liquid phase in the mercury oxidation step. |
| US09884285B2 |
Method for removing dust and sulphur oxides from process gases
The invention relates to a method for removing solids in dust and sulphur oxides from process gases generated in a metallurgical process by a wet process. At least part of basic liquid is fed into the gas flow containing solids in at least one cascade scrubber in order to mix basic liquid with the gases and solids to be cleaned at the latest during the wetting of the gases and solids in the water space of the cascade scrubber, and the mixture containing basic liquid, wetted gases and solids are directed to have a cascade shower in each cascade scrubber in order to remove sulphur and solids from the gases. |
| US09884284B2 |
Dehumidifying unit, layered temperature control dehumidifying element and drying device
A dehumidifying unit, a layered temperature control dehumidifying element and a drying device are provided. The dehumidifying element has a plurality of dehumidifying units. The dehumidifying units are made of a direct heating desorption material and used for dehumidifying air by adsorption and capable of being regenerated by desorption. By performing temperature compensation through a preheater and performing a layered temperature control method on the dehumidifying element, the disclosure achieves a uniform temperature control on the air flow passage of the dehumidifying element so as to improve regeneration performance of the dehumidifying element and reduce energy consumption of the drying device. |
| US09884279B2 |
Filter apparatus with ejection arrangement
A filter cartridge including catches for ejecting the filter cartridge from a filter housing as the filter cartridge and filter housing are removed from a filter base is provided. The catches are configured to engage corresponding catches of the filter base to limit axial motion of the filter cartridge as the filter cartridge and filter housing are threadedly removed from the filter base. |
| US09884274B2 |
Filter apparatus
A filter apparatus has a filter housing (1) accommodating at least one filter element (17) having an inner filter cavity (23) enclosed by a filter medium (27). The housing (1) contains an element holder (19) that interacts with the filter element (17) located in its functional position. The element holder (19) has a projecting accommodating part (43) with an outer configuration adapted to the shape of an opening (37) located at the end of the filter element (17) to be secured to the element holder (19). The accommodating part (43) fits through the opening (37) of the filter element (17) located in the functional position. |
| US09884273B2 |
Fluid filter assembly incorporating drawn down cover plate
A fluid filter assembly is provided comprising a filter can, a filter cover assembly, and an interior filtering assembly. The filter cover assembly comprises an outer cover plate and an inner mounting plate. The outer cover plate of the filter cover assembly comprises a drawn-down portion that descends toward the interior volume of the fluid filter assembly and exhibits a metallic grain structure that is stretched relative to the metallic grain structure of the inner and outer circumferential mating portions of the outer cover plate. In one embodiment, the inner mounting plate is secured to a backside of the outer cover plate such that, upon rotational engagement of the internal threads of the inner mounting plate with a threaded fluid port, the inner mounting plate rotates with the filter can and the outer cover plate to advance in an axial engagement direction and forcibly urge the outer cover plate in the axial engagement direction from the backside of the outer cover plate. |
| US09884264B2 |
Divided wall distillation column for producing high purity acrylic acid and fractional distillation method using the same
There are provided a dividing wall distillation column for producing high-purity acrylic acid, and a fractional distillation method using the same. The dividing wall distillation column includes a condenser, a reboiler and a main column having a dividing wall. Here, the main column is divided into a column-top zone, an upper feed zone, an upper outflow zone, a lower feed zone, a lower outflow zone and a column-bottom zone. Also, a crude acrylic acid raw material (F) flows in a middle inflow plate NR1 in which the upper feed zone and the lower teed zone come in contact with each other, a low boiling point component (D) flows out from the column-top zone, a high boiling point component (B) flows out from the column-bottom zone, and a middle boiling point component (S) flows out through a middle outflow plate NR2 in which the upper outflow zone and the lower outflow zone come in contact with each other. In this case, the middle boiling point component is acrylic acid. Accordingly, since one distillation column can be used to realize the same effect as that obtained from the use of two distillation columns, the dividing wall distillation column can have an effect of reducing the costs of equipment to produce high-purity acrylic acid, as well as an energy-reducing effect, compared to a conventional process system. |
| US09884262B2 |
Bubble generating apparatus
A bubble generating apparatus includes an air flow generator, a liquid tray defined by a floor and sidewalls and having one or more bubble forming ports therein, and a pivot arm coupled to a motor for pivoting the pivot arm about an axis so that during pivoting a bubble generating member of the pivot arm passes over one of the bubble forming ports, the air flow generator positioned to direct an air stream through the one or more bubble forming ports, and a gravity feed liquid reservoir, wherein the liquid tray is configured to generate bubbles from the liquid when the air flow generator directs the air stream through the one or more bubble forming ports while the pivot arm pivots about the axis. |
| US09884260B2 |
Water toy
A bath toy system including a water play space delimiter arranged to be located in a water-filled bath and to define a water play space separate from a remainder of the water filled bath, a water spray assembly generating at least one water spray within the water play space and at least one floatable fanciful element floatable on the water within the water play space. |
| US09884254B2 |
Augmented reality gaming systems and methods
An augmented reality (AR) game system is disclosed wherein real-world objects are transformed into AR terrain elements and AR events generate real-world impact. The game environment is set up using real-world objects that include everyday objects and game pieces on a field of play. When viewed on the screen of a computing device executing the modules of the game system, the everyday objects are transformed into elements of an AR terrain while the game pieces can be augmented with various controls. Multiple viewing modes, for example, a third person view, a first person view or “POV” view from a selected game piece or a split screen view are contemplated for viewing the field of play. A subset of the augmented controls can be activated by the user to execute AR events some of which can have real-world impact. The AR events are executed based on game rules. Detection mechanisms such as colored detection can be used for detecting positions of game pieces within the field of play. |
| US09884250B2 |
Directional game controller
The invention has for object a game controller having an actuator (2, 102) mobile in rotation in relation to a fixed part (3, 103), in such a way as to simulate a control of the rotation of a steering column of a simulated vehicle.According to the invention, the game controller implements means for detecting the displacement in rotation of the actuator (2, 102) comprising at least one Hall effect or magnetoresistive effect detecting unit, constituted of at least two elements, of which a permanent magnet and a magnetic sensor (24, 124). At least during the rotation of the actuator (2, 102), a first element is integral in rotation with the actuator (2, 102) and a second element is integral in rotation with said fixed part (3, 103). |
| US09884248B2 |
Display control method for head-mounted display (HMD) and image generation device
The position and the posture of an HMD, and the position of a game controller in the real space are detected, and tracked. An image of a virtual space is displayed on the HMD. A controller object is disposed and displayed at a position within the virtual space that corresponds to the position of the game controller in the real space viewed from the HMD. Therefore, the player can easily find and hold the game controller even when the player wears the HMD. |
| US09884247B2 |
System for processing gaming activity
Embodiments of the present invention are directed to a gaming device configured to record gaming activity, a method of processing the recorded gaming activity to analyze player behavior, and a system including the gaming device. The gaming device may include a gaming display to display gaming events played on the gaming device by a player during a gaming session, a player interface panel including a plurality of gaming buttons and a game initiating button configured to initiate the gaming events, and a game processor configured to record each activity between the player and the gaming device, wherein each recorded activity is associated with a time stamp. |
| US09884246B2 |
Video game processing apparatus and video game processing program
A video game processing apparatus for controlling progress of a video game is provided. An image display device is caused to display operating section images in an operating section image display area on a display screen in an arrangement pattern corresponding to arrangement positions of respective operating sections. The operating section images are operating section images respectively corresponding to the operating sections arranged in the operational input section. Identification display allowing a player to identify the operational function associated with the corresponding operating section is made for each of the group of operating section images. When to receive an operational input in response to an operation of any of the plurality of operating sections by the player, the video game processing apparatus carries out operation correspondence processing that indicates processing to exert an operational function associated with the operating section operated by the player. |
| US09884244B1 |
Sports board configuration
A component of a sports board may be controlled to configure the sports board. The component may be coupled with at least one layer of the sports board. |
| US09884240B2 |
Three dimensional knee and elbow pads
A sports pad is provided including an outer shell defining a pocket and a pad received and held in the pocket. A three dimensional image element is captured between said outer shell and the front face of the pad. That image element projects an image outline through the outer shell to enhance the uniform of the player wearing the sports pad. |
| US09884238B2 |
Rotating force sensing kickboxing apparatus
A rotating force sensing kickboxing apparatus is disclosed. An example apparatus includes a support member including a first connector located at a bottom portion of the support member and a body. The apparatus also includes a sensor attached to the body, the sensor configured to detect an object striking a portion of an exterior side of the body. The apparatus further includes a stand including a circular recessed channel and a second connector secured within the circular recessed channel and configured to connect to the first connector. The second connector is configured to rotate within the circular recessed channel. The connection of the first connector to the second connector enables the body and the support member to be rotatable with respect to the stand. |
| US09884237B2 |
Bicycle trainer
A bicycle trainer includes a base frame including a first pivot connection part, a damper unit mounted at the base frame, a support frame including a locating portion and a second pivot connection part, which is pivotally connected to the first pivot connection part of the base frame for enabling the support frame to be biased relative to the base frame in direction away from or toward the damper unit such that when the support frame is held in an inclined position relative to the base frame, the locating portion and the damper unit can hold a wheel of a bicycle in place, and a non-return unit mounted at the base frame or support frame and adapted to prohibit the support frame from being biased in direction away from the base frame. The invention enables the support frame to be constrained by the non-return unit. |
| US09884236B2 |
Removable paddle attachment device
A removable paddle attachment assembly is provided. The attachment assembly may include a attachment bracket terminating at opposing saddles, a handle saddle for engaging a first portion of a watercraft paddle and an activity saddle for engaging an activity device, whereby the activity device is removably yet rigidly secured to the watercraft paddle so that the activity device may be employed for game-playing and/or exercise-training purposes, while not impairing the performance and functionality of the watercraft paddle. The attachment bracket provides at least one attachment strap cleat so that a attachment strap may be stretched from one lateral surface of the attachment bracket to an opposing lateral surface thereof, thereby securely sandwiching the first and a second portion of the watercraft paddle against the handle saddle. |
| US09884233B2 |
Golf clubs and golf club heads having digital lie and/or other angle measuring equipment
Golf club heads having sensors configured to measure one or more swing parameters are provided. The golf club head may include several gyroscopes and accelerometers. In one embodiment, the club head contains three gyroscopes that measure angular rate data along different orthogonal axes. At least one gyroscope may an analog gyroscope. Accelerometers may provide data regarding the three orthogonal axes associated with the gyroscopes. The club head may further include software and/or hardware that perform computer-executed methods for determining one or more swing parameters. Exemplary club heads may include a display device for displaying an output of the swing parameter(s). Further aspects of the invention relate to novel methods and algorithms for calculating measurements relating to the swing parameters. |
| US09884229B2 |
Titanium alloy for golf club face
The present invention provides, as a material for a golf club face of a driver, an iron or the like, a titanium alloy which satisfies the regulation for a coefficient of restitution, and has high Young's modulus and tensile strength and also has excellent hot and cold workability. The titanium alloy for a golf club face according to the present invention comprises, in percent by mass, 1.0 to 3.5% of Al, 0.5 to 1.4% of Fe, 0.2 to 0.5% or O and 0.002 to 0.030% of N, and the balance of Ti with inevitable impurities, wherein an α-phase is strengthened by combined addition of O and Al, and inexpensive Fe is selected as a β-phase stabilizing element, leading to high strength and high Young's modulus in combination. The content of Al causing deterioration of hot workability is limited to a low value, leading to low rolling load during hot rolling, and thus flaws and edge cracking are unlikely to occur during hot rolling. |
| US09884221B2 |
Exercise bench with enhancements that allow the obese, elderly, and physically challenged to participate in exercises performed on a conventional exercise bench
An exercise bench that allows elderly, obese, and physically challenged individuals to participate in the same exercise regimens as younger, more agile athletes is provided. The exercise bench of the current invention comprises cushioned side supports that stabilize the individual during reclining and during exercise. Due to the nature of the exercises performed in the prone position, an exercise bench is generally narrow in order to allow freedom of movement for the Individual's arms. The narrow bench can provide stability challenges for elderly and obese individuals which the side support cushions address by providing the required stability without interfering with the individual's range of arm motion for exercising. The present invention also includes mechanical means to assist the user in reclining to a prone position, and returning to an upright sitting position. Many individuals who want to use a conventional exercise bench are prohibited from doing so because they lack the abdominal strength to lie down slowly from a sitting position, and return to a sitting position after exercising without assistance. The exercise bench of the current invention overcomes these obstacles. |
| US09884219B2 |
Exercise apparatus
An exercise apparatus comprises an elongate support member extending along a length between first and second ends. The rigid member has a passage extending therethrough between the first and second ends. The apparatus further comprises a handle extending between first and second handle ends, the handle having connectors proximate to each of the first and second ends and a grip section therebetween and at least one elongate flexible member extending through the passage of the support member and having end connectors on each end thereof, the at least end connectors being connectable to one of the connectors of the handle. |
| US09884216B2 |
Electrically operated gas vents for fire protection sprinkler systems and related methods
A fire protection sprinkler system includes a water source, a sprinkler, a piping network interconnecting the water source and the sprinkler, and an automatic gas vent coupled to the piping network and configured to discharge gas from the system. The automatic gas vent includes a sensor configured to sense a presence or absence of a liquid and an electrically operated valve. The automatic gas vent is configured to open the electrically operated valve in response to the sensor sensing the absence of a liquid and close the electrically operated valve in response to the sensor sensing the presence of a liquid. Automatic gas vent assemblies and methods of venting and discharging gas from fire protection sprinkler systems are also disclosed. |
| US09884214B1 |
Hose winding device
The hose winding device has an open rectangular parallelepiped skeleton frame made of tubular members. The upper cross members at opposite ends of the frame include a lower wringer roller mounted on a shaft fixed to opposite sides of the frame and an upper wringer roller spaced above the lower wringer roller. The wringer rollers compress and flatten the fire hose as it is cranked through the wringer rollers, thereby removing any water left inside the hose. A pair of spaced apart, vertical guide rollers are mounted closely behind the wringer rollers, the four rollers being configured similar to a winch's roller fairlead, permitting the hose to be smoothly wound on the device without first straightening the hose. A hand crank is removably mounted to opposite sides of the frame halfway between opposite ends of the frame. The crank has a hose coupler retainer extending parallel to the crank's axle. |
| US09884212B2 |
Anechoic chamber fire suppression system
A fire suppression system for anechoic chambers with multiple non-retractable tubes fixed on the ceiling of the chamber, with each tube connected to a pneumatic valve. Each valve is controlled by a compressed air supply that reacts to the presence of fire in the chamber. Once fire is detected in the chamber, the valves vent the compressed air to permit fire retardant fluid to pass through the fixed tubes into the chamber. The tubes and the valves do not interfere with the functions of the chamber and provide immediate fire suppression. |
| US09884211B2 |
Fall arrest device
A fall arrest device comprises a guide (3) for a track member (7) which, in use, passes through the device, a cam member (9) including a cam portion, and a clutch (21) responsive to at least one of the relative speed and relative acceleration of the fall arrest device and the track member. The clutch serves to determine when the relative speed and/or acceleration is at least a predetermined value. The clutch includes a trigger arm (19) connecting to the cam member so as to move the cam portion of the cam member toward the guide so as to lock the track member between the cam member and the guide when at least the predetermined value is attained. |
| US09884210B2 |
Aircraft passenger oxygen mask with closed circuit concept
The invention relates to an aircraft passenger emergency oxygen supply device comprising an oxygen mask having a mask body with a first opening for covering mouth and/or nose of the passenger, a second opening connecting said first opening with a source of oxygen, a passenger service unit, a connecting line fixed to the oxygen mask body at one end and having a coupling at the other end for coupling said line to the passenger service unit wherein a chemical reaction component is comprised in the oxygen mask. |
| US09884208B2 |
Position determination
An apparatus for position-detection of an object within a region is disclosed. The apparatus includes first and second target elements mounted on an object and having a known separation distance between the two. A scanning light source is configured to issue a beam of light along a substantially one-dimensional scanning path, which illuminates a point that moves over the first and second target elements. A detector is provided for detecting light reflected from, or received by, the first and second target elements. A processing system is configured to determine the position of the object within the region based on first and second points in the scanning path at which the detector detects light returned from, or received by, the first and second target elements and the known separation distance between the two reflective elements. |
| US09884206B2 |
Systems and methods for intensity modulated radiation therapy
Embodiments disclosed herein include methods for performing intensity-modulated radiation therapy on a subject using a plurality of pencil beams. The methods can include generating a treatment plan for intensity-modulated radiation therapy that satisfies dose constraints for each of a plurality of sub-volumes. The treatment plan can be generated using a superiorization technique that reduces total variation in dose space. Additional dose-volume constraints that permit a fraction of treatment doses to violate a prescription by up to a defined percentage of intensity can be used to assist in determining the treatment plan. |
| US09884203B2 |
Medical and veterinary applications of light to antimicrobial and antineoplastic chemicals
A device having medical and veterinary applications of light to antimicrobial and antineoplastic chemicals includes a solution retainer adapted to retain a therapeutic solution against a user, the therapeutic solution including an antimicrobial chemical, an antineoplastic chemical, or both; a fiber optic cable; a light termination on the fiber optic cable that provides light from the fiber optic cable to the therapeutic solution in the solution retainer; and a light source that provides a light of a predetermined wavelength to the fiber optic cable; wherein the light provides a synergistic effect in the therapeutic solution that inhibits microbial or neoplastic growth. |
| US09884200B2 |
Apparatus for coil positioning for TMS studies
A method and device provide simple positioning of a TMS coil relative to a coordinate system of the patient's head while allowing flexible positioning of the patient's head. The system includes a mobile console on a wheeled base that integrates various subsystems and supports a mast that, in turn, supports a coil gantry that supports a TMS coil assembly. The coil gantry includes a balance arm with a counterbalance and a halo assembly that connects to the coil. The coil gantry supports the weight of the coil and allows free movement of the coil in all dimensions for easy placement on the patient's head. A head support and coil alignment aligns the patient's head and holds the head in place relative to the coil during TMS treatment. |
| US09884199B2 |
Methods and apparatus for treatment of chronic kidney disease
A method and apparatus for treatment of chronic kidney disease (CKD), particular diabetic nephropathy, are disclosed. The method comprises activation of adenosine A2a receptors in parenchymal and immune cells infiltrated into kidneys. The activation is performed by PEMF (pulsed electromagnetic field) stimulation applied locally to kidneys. Adenosine A2a signaling pathway is a potent anti-inflammatory and immuno-suppressive regulator that has been proven to attenuate inflammation and injury in diabetic nephropathy. Efficient activation of A2a receptors is achieved by applying electromagnetic field stimulation consecutively in 3 spatial dimensions. This allows attaining a significant increase in activation of A2a receptors in comparison with one-dimensional stimulation. Assistant thermal stimulation may be applied to increase expression of heat shock proteins (HSPs) in parenchymal cells. HSPs improve protein functions, protect cells from apoptosis and necrosis, increase metabolism, and symbiotically enhance effects of electric stimulation on CKD. |
| US09884198B2 |
Systems and methods for extending the life of an implanted pulse generator battery
Systems and methods for extending the life of an implanted pulse generator battery are disclosed. A representative method for establishing charge parameters for a battery-powered implantable medical device includes receiving a patient-specific therapy signal parameter and, based at least in part on the patient-specific therapy signal parameter, determining a discharge rate for a battery of the implanted medical device. The method can further include determining a therapy run time, based at least in part on the discharge rate. The method can still further include determining at least one battery charging parameter, based at least in part on the run time. |
| US09884195B2 |
Delaying the onset of muscle fatigue associated with functional electrical stimulation
The present invention relates a system that can configure a stimulus for functional electrical stimulation (“FES”) to maintain a constant muscle force while delaying the onset of muscle fatigue and a related method of use. The stimulus can be delivered to a nerve via a set of multiple electrode contacts according to a stimulation parameter that maximizes a joint moment associated with the stimulus and minimizes the overlap between pairs of contacts. The joint moment can be related to the muscle force, and the overlap can be related to the onset of muscle fatigue. |
| US09884192B2 |
Onset-mitigating high-frequency nerve block
A method of blocking signal transmission through a nerve with reduced onset activity includes applying an HFAC to an axon of a nerve to block the transmission of signals through the axon. The method may also include applying a direct current (DC) to the axon, increasing the amplitude of the DC over time to a predetermined amplitude, applying the HFAC, and then decreasing the DC. The method may also include temporarily reducing the amplitude of the HFAC to permit the transmission of signals through the axon and subsequently increasing the amplitude to block transmission without triggering an onset response. The method may also include temporarily applying an unbalanced charge to the nerve and then balancing the charge over time. |
| US09884190B2 |
Surgical method for implantable head mounted neurostimulation system for head pain
A method for subcutaneously treating pain in a patient includes first providing a neurostimulator with an IPG body and at least a primary integral lead with electrodes disposed thereon. A primary incision is opened to expose the subcutaneous region below the dermis in a selected portion of the body. A pocket is then opened for the IPG through the primary incision and the primary integral lead is inserted through the primary incision and routed subcutaneously to a first desired nerve region along a first desired path. The IPG is disposed in the pocket through the primary incision. The primary incision is then closed and the IPG and the electrodes activated to provide localized stimulation to the desired nerve region and at least one of the nerves associated therewith to achieve a desired pain reduction response from the patient. |
| US09884189B2 |
Systems and methods to place one or more leads in tissue for providing functional and/or therapeutic stimulation
Systems and methods make possible the placement of one or more electrode leads in a tissue region for providing functional and/or therapeutic stimulation to tissue. The systems and methods are adapted to provide the relief of pain. |
| US09884186B2 |
Apparatus for physiological mechanism activation and the method comprising the same
The present invention is related to an apparatus for activating electrophysiological mechanism and the method for configuring the same, which are based on diagnostic codes comprising at least more than two codes selected from a group of code classified by hue contrast to temperature differences according to heat distribution of a body. As a prescription for the above diagnostic codes, the activation prescription codes comprising code streams are generated, and then signals corresponding to each code are sequentially extracted and outputted as stimuli, and then finally become to provide activation stimuli to a body. The apparatus according to the present invention measures the distribution of body temperature, sets potential difference within an isolated system according to the distribution, and thus forces vibrations or waves with accelerated motion to be delivered to a whole body. Therefore, the present invention provides effects for being observed for electrophysiological mechanism, in which stimuli for physical treatment are delivered to a whole body as well as a special part of a body. |
| US09884185B2 |
Intracardiac capsule implantable on a thin wall, including the septum wall
An intracardiac capsule comprises a cylindrical body having an atraumatic rounded surface and a helical anchoring screw integral with the cylindrical body. The helical anchoring screw is able to penetrate tissue of a wall of the heart and is configured to provide temporary attachment, in rotation and in translation, of the capsule to an implantation site. The helical anchoring screw surrounds at least a portion of the length of the cylindrical body forming a contact region intended to come into contact with the wall of the cavity of the heart. Over the length of the contact region, the external diameter of the cylindrical body is less than the inner diameter of the helical anchoring screw, so as to leave a free gap there between. The helical anchoring screw is secured to the cylindrical body near the proximal end of the contact region, and extends freely to the opposite distal end. |
| US09884184B2 |
Wire hook coupling for lead extension and extraction
A device for extending a lead according to an embodiment of the present disclosure includes a body having proximal and distal ends, the distal end having first and second apertures, the body having an inner lumen, the first and second apertures extending from an outside of the body to the inner lumen; a filamentous element extending out of the first aperture and into the second aperture to form a filament loop extending from the body; a tightening mechanism configured to twist the filamentous element to compress a lead body between the filament loop and the body; and a tether coupled to body and configured to extend further proximally than a proximal-most end of the lead body when the lead body is compressed between the filament loop and body, the tether further configured to transfer at least a portion of a tension force applied to the tether to the lead body. |
| US09884182B2 |
Catheter system for acute neuromodulation
A neuromodulation system includes a first therapy element adapted for positioning within a superior vena cava, and a second therapy element adapted for positioning within a pulmonary artery. The first therapy element is carried on a first elongate flexible shaft, and the second therapy element is carried on a second elongate flexible shaft. One of the first and second shafts is slidably received within a lumen of the other of the first and second shafts—so that the second therapy element may be advanced within the body relative to the first therapy element. A stimulator is configured to energize the first therapy element within the first blood vessel to deliver therapy to a first nerve fiber disposed external to the superior vena cava and to energize the second therapy element within the pulmonary artery to deliver sympathetic therapy to a second nerve fiber disposed external to the pulmonary artery. For treatment of heart failure, the first nerve fiber may be a vagus nerve and the second nerve fiber may be a sympathetic nerve fiber. |
| US09884180B1 |
Power transducer for a retinal implant using a contact lens
Apparatus, systems and methods employing contact lens as power source for powering a retinal implant are provided. In an aspect, a contact lens includes a substrate that forms at least part of a body of the contact lens and a circuit disposed on or within the substrate comprising. The circuit includes a power harvesting component configured to receive energy in a first form from an external power source and convert the energy from the first form to a second form and an energy transfer component configured to transmit the energy in the second form to device remote from the contact lens when the contact lens is worn over an eye. |
| US09884179B2 |
Neural sleeve for neuromuscular stimulation, sensing and recording
The present disclosure relates to neuromuscular stimulation and sensing cuffs. The neuromuscular stimulation cuff has at least two fingers and a plurality of electrodes disposed on each finger. More generally, the neuromuscular stimulation cuff includes an outer, reusable component and an inner, disposable component. One or more electrodes are housed within the reusable component. The neuromuscular stimulation cuff may be produced by providing an insulating substrate layer, forming a conductive circuit on the substrate layer to form a conductive circuit layer, adhering a cover layer onto the conductive circuit layer to form a flexible circuit, and cutting at least one flexible finger from the flexible circuit. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement. |
| US09884178B2 |
Neuromuscular stimulation cuff
The present disclosure describes systems, methods, and devices for performing thought-controlled neuromuscular stimulation. Also described are methods for producing a neuromuscular stimulation cuff. The systems and methods generally relate to receiving and processing thought signals indicative of an intended action, and then delivering stimulation to effectuate the intended action through a neuromuscular stimulation cuff. The neuromuscular stimulation cuff includes a flexible printed circuit board having at least one finger and a plurality of electrogel discs disposed on the at least one finger. The neuromuscular stimulation cuff may be produced as described herein. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement. |
| US09884174B2 |
Medical device for detection of a leakage of fluid on a subject
A medical device for detecting a leakage of fluid on a subject includes a support, configured for being secured on the subject, and an optical sensor on the support. The support defines, in a region between the optical sensor and a lower face thereof, a detection surface that can be reached by leakage fluid. The optical sensor is arranged for detecting a leakage of fluid. The optical sensor has a sensor body with an emitter and a receiver of electromagnetic radiation. The support and the sensor body have mutual-coupling means, for retaining the sensor body on the support in such a way that a presence of leakage fluid can be detected via the optical sensor. |
| US09884172B2 |
Reinforced balloon catheter
One embodiment of the present invention discloses a balloon catheter employing a reinforced, co-axial, duel lumen design. In certain embodiments, at least one of the lumens is formed of a multilayer, tubular element in which one of the layers functions, in part, to provide radial reinforcement to the tubular element. |
| US09884168B2 |
Temporary retention device
A retention device for anchoring indwelling catheters, sheath introducers, feeding tubes, ostomy bags or other medical devices beneath the skin of a patient includes an deployable section coupled to a medical device; following introduction into a patient, the deployable section is subcutaneously deployed, securely anchoring the device and coupled medical device for the duration of treatment. |
| US09884167B2 |
Catheter with partially slitted insertion aid
A tubular insertion aid for catheter manipulation is disclosed. The insertion aid is particularly suited for urinary catheters, such as hydrophilic urinary catheters for intermittent use. The insertion aid comprises a forward opening, a rearward opening and a slit opening extending along a part of the sidewall of the tubular insertion aid, so that a first portion of the tubular insertion aid in the axial direction forms a solid circumference around the tubular insertion aid, and a second portion in the axial direction is provided with the slit opening extending in an axial direction of the tubular insertion aid. The tubular insertion aid further comprises a first inward protrusion formed on the interior side of the tubular insertion aid in a part of the second portion being provided with the slit, wherein the first inward protrusion is arranged along a first protrusion line extending along the inward circumference of the tubular insertion aid essentially perpendicularly to the axial direction of the tubular insertion aid. |
| US09884166B2 |
Jetless intravenous catheters and mechanical assist devices for hand-injection of contrast media during dynamic tomography and methods of use
A jetless intravenous catheter for the delivery of a fluid into a peripheral vein of a subject includes an elongated body having proximal and distal ends. The body includes a wall defining an internal fluid passageway configured to receive fluid flowing in a longitudinal direction from the proximal end at a first axial velocity and a tip aperture at the distal end configured to allow fluid to exit therethrough. The body comprises at least one flow reducing feature configured to create a laminar-turbulent transitional flow associated with a fluid flowing in the longitudinal direction at the first axial velocity and configured to reduce the flow velocity of fluid exiting the tip to a second axial velocity that is less than the first axial velocity. |
| US09884165B2 |
Multi-lumen catheter including an elliptical profile
A multi-lumen catheter including an elliptical cross-sectional profile configuration that enhances fluid flow rate while minimizing the average diameter of the catheter body is disclosed. In one embodiment the catheter comprises an elongate catheter tube defining a plurality of lumens. At least a portion of the longitudinal length of the catheter tube defines an elliptical cross section, in turn defined by a major axis and a minor axis. A ratio of the major axis to the minor axis of the elliptical catheter tube cross section is between about 1.3 and about 1.4 in one embodiment. The catheter body can define two, three, or more lumens, in one embodiment. |
| US09884161B2 |
Apparatus for fluid tube
A fluid tube is disclosed herein. The breathing circuit tube has a wall which comprises a hollow geometry. The wall defines a passageway with a central longitudinal axis therethrough. The wall is expandable and contractible to adjust a diameter and a length of the passageway. The wall includes one or more corrugations that expand and contract to adjust the diameter and length of the passageway. The corrugations extend between terminal end portions of the wall. |
| US09884155B2 |
Film-based protective mechanism
The invention relates to a method for producing a device containing a needle that poses an injury risk, which is equipped with a protective mechanism. The method comprises the following steps, which may be carried out in any order: a) provision of at least one film, b) connection of the film to a protective device to form a protective mechanism, and c) fixing of the protective mechanism to the device, whereby at least part of the surface of the film can be fixed directly or indirectly to the device. The invention also relates to a protective mechanism for a device containing a needle that poses an injury risk, the device comprising at least one film, in addition to an assembly of protective mechanisms, in which the protective mechanisms are directly or indirectly connected. |
| US09884151B2 |
Reconstituting infusion device
A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed. |
| US09884144B2 |
Hemodialysis system with cassette-based blood and dialysate pumping
A hemodialysis system includes: (i) a dialyzer; (ii) a dialysate source; a dialysate pump; (iii) a dialysate cassette operatively connected to the dialysate pump such that the dialysate pump can pump dialysate through the dialysate cassette when the dialysate cassette is in fluid communication with the dialysate source, the dialysate cassette in fluid communication with the dialyzer; (iv) a blood pump; and (v) a blood cassette separate from the dialysate cassette, the blood cassette operatively connected to the blood pump such that the blood pump can pump blood through the blood cassette, the blood cassette including a housing, the housing including a from-patient tube connector, a to-patient tube connector, a saline/priming tube connnector, a to-dialyzer tube connector, a from-dialyzer tube connector, and an internal air separation chamber. |
| US09884133B2 |
Electric device for the evaporation of volatile substances
The present invention refers to an electric evaporation device with adjustable evaporation intensity, wherein a shield member (4) is displaceable between a minimum evaporation position in which it is interposed between a heating resistor (5) and an upper part of a wick (3), and a maximum evaporation position in which part of the shield member is located below said resistor (5). Since the shield member (4) is moved downwardly below the resistor (5), the upper end (13) of the wick (3) be located very close to an aperture (10) for the exit of the vaporized substance. |
| US09884132B2 |
Homomultivalent and heteromultivalent inhibitors of prostate specific membrane antigen (PSMA) and uses thereof
The present invention provides bivalent and multivalent ligands with a view to improving the affinity and pharmacokinetic properties of a urea class of PSMA inhibitors. The compounds and their synthesis can be generalized to multivalent compounds of other target antigens. Because they present multiple copies of the pharmacophore, multivalent ligands can bind to receptors with high avidity and affinity, thereby serving as powerful inhibitors. The modular multivalent scaffolds of the present invention, in one or more embodiments, contains a lysine-based (∝, ε-) dialkyne residue for incorporating two or more antigen binding moieties, such as PSMA binding Lys-Glu urea moieties, exploiting click chemistry and one or more additional lysine residues for subsequent modification with an imaging and/or therapeutic nuclides or a cytotoxic ligands for tumor cell killing. |
| US09884124B2 |
Carriers for improved drug delivery
The invention provides carriers that enhance the absorption, half-life or bioavailability of therapeutic compounds. The carriers comprise targeting groups that bind the Vitamin D Binding protein (DBP), conjugation groups for coupling the targeting groups to the therapeutic compounds, and optionally scaffolding moieties. |
| US09884119B2 |
Lipid layer forming composition for administration onto a surface of a living organism
A lipid layer forming composition comprises a volatile silicone oil of a boiling point above 180° C., a polar lipid, optionally a C2-C4 aliphatic alcohol, optionally a pharmacologically or cosmetically active agent or a protective agent. The lipid layer forming composition can be applied to a biological surface by spraying, dipping or brushing to form a stable polar lipid layer on the surface. |
| US09884118B2 |
Multicomponent degradable cationic polymers
Degradable polymers were synthesized that self-assemble with DNA to form particles that are effective for gene delivery. Small changes to polymer synthesis conditions, particle formulation conditions, and polymer structure provides significant changes to efficacy in a cell-type dependent manner. Polymers presented here are more effective than commercially available materials, such as LIPOFECTAMINE 2000™, FUGENE®, or polyethylenimine (PEI), for gene delivery to cancerous fibroblasts or human primary fibroblasts. The presently disclosed materials may be useful for cancer therapeutics and regenerative medicine. |
| US09884114B2 |
Methods of rational nicotine hapten design and uses thereof
Provided herein are methods for rational design of nicotine haptens. More particularly, provided herein are methods for designing, selecting, and synthesizing nicotine haptens and nicotine hapten conjugates. Also provided herein are novel nicotine haptens and methods for using nicotine haptens to treat nicotine addiction. |
| US09884110B2 |
Methods and compositions for eliciting an immune response against hepatitis B virus
The present invention relates to immunization of hypo-responsive groups of individuals. In particular, the present invention provides methods and compositions for eliciting a potent immune response to hepatitis B virus in individuals in need thereof. |
| US09884106B2 |
Influenza nucleic acid molecules and vaccines made therefrom
Provided herein are nucleic acid sequences that encode novel consensus amino acid sequences of HA hemagglutinin, as well as genetic constructs/vectors and vaccines expressing the sequences. Also provided herein are methods for generating an immune response against one or more Influenza A serotypes using the vaccines that are provided. |
| US09884105B2 |
Production of viral vaccine
The present invention relates, in general, to materials and methods for production of an improved vaccine against influenza virus, wherein the vaccine comprises a reassortant virus having a hemagglutinin gene and a neuraminidase gene from the same influenza A virus subtype or influenza B strain of virus and internal genes from a different influenza A virus subtype or influenza B strain of virus. In one aspect, the HA and NA genes and the internal genes are from a highly pathogenic H5N1 strain of influenza A. |
| US09884101B2 |
Treatment and prevention of malaria
The present invention relates to recombinant fragments of Plasmodium polypeptides and polynucleotides encoding same. The invention further relates to compositions comprising the recombinant fragments of Plasmodium polypeptides and their use in the treatment and prevention of malaria. |
| US09884099B2 |
Compositions and methods of enhancing immune responses to Eimeria or limiting Eimeria infection
Vaccine, vectors and methods of using the vaccine vectors to enhance the immune response to an Apicomplexan parasite and reduce the morbidity or mortality associated with subsequent infection are provided herein. The vaccine vectors include a polynucleotide encoding a Rhomboid polypeptide and optionally include an immune-stimulatory polypeptide suitably expressed on the surface of the vaccine vector. |
| US09884091B2 |
Treatment of neurological diseases
Methods treat neurological disorders, for example neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and stroke. Particularly although not exclusively, GIP/GLP-1 co-agonist peptide is used in the treatment of such neurological disorders. Pharmaceutical compositions include a GIP/GLP-1 co-agonist peptide for use in treatment of such disorders. |
| US09884089B2 |
BPI and its congeners as radiation mitigators and radiation protectors
Described herein is a method of mitigating, in a subject (individual), tissue injury resulting from exposure to radiation (accidental/unintentional or intentional, such as therapeutic), chemoradiotherapy, disease, toxin, or drug or biologic mediated therapy. |
| US09884082B2 |
Compositions and methods for alleviating hyposalivation and for providing oral comfort
Various compositions and methods are provided to alleviate one or more symptoms associated with hyposalivation and/or xerostomia. Preferred compositions and methods employ one or more plant pulp products and/or a proanthocyanidin at a concentration effective to reduce or eliminate the symptoms. Especially preferred product components are isolated from a fruit and/or seed (e.g., grape, cranberry, blue berry, black berry, etc.), and where a second component is preferably a freeze-dried pulp from a citrus fruit (e.g., lemon, orange, lime, grapefruit, tangerine, mandarin orange, ugli fruit, etc.) not containing peel or juice therein. |
| US09884077B2 |
Extract and preparation containing said extract
An extract from inflamed skins of rabbits inoculated with vaccinia virus is provided where the quality of the extract is more stabilized. A preparation, etc. containing said extract as an active ingredient is also provided. When the amount of sulfated tyrosine contained in an extract from inflamed skins of rabbits inoculated with vaccinia virus and also contained in a preparation containing said extract as an active ingredient is used as an index, the quality of the extract and the preparation among the manufacturing lots can be warranted as a more stabilized one. In the extract from inflamed skins of rabbits inoculated with vaccinia virus and the preparation containing said extract where the quality thereof is more stabilized by such a method, the efficacy and the safety thereof are now guaranteed more strictly resulting in very high usefulness. |
| US09884074B2 |
Bi-functional co-polymer use for ophthalmic and other topical and local applications
The invention contemplates a copolymer which is a graft or block copolymer useful to change wettability and surface characteristics of biological surfaces. Methods for use of these formulations and coatings to change wettability and sterically stabilize, and lubricate biological surfaces in a subject, for example, in the treatment of dry eye syndrome, and to prevent adherence of unwanted proteins, for example in the treatment of contact lens intolerance, are provided. |
| US09884072B2 |
Methods and compositions for modulating apolipoprotein (a) expression
Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a) or Lp(a). Certain diseases, disorders or conditions related to apo(a) or Lp(a) include inflammatory, cardiovascular and/or metabolic diseases, disorders or conditions. The antisense compounds disclosed herein can be used to treat such diseases, disorders or conditions in an individual in need thereof. |
| US09884069B2 |
Osteoclast inhibitors for knee conditions
Oral, parenteral, and intravenous dosage forms of osteoclast inhibitors, such as neridronic acid, can be used to treat or alleviate pain or related conditions, such as knee pain. |
| US09884066B2 |
Bile acid-basic amino acid conjugates and uses thereof
Compositions and methods for treating diseases or disorders associated with the metabolic syndrome using conjugates of bile acids with basic amino acids or a decarboxylated amino acid such as agmatine are provided. Further provided are bile acid-basic amino acid conjugates including chenodeoxycholic acid with an amino acid selected from arginine, lysine, histidine, ornithine or a decarboxylated amino acid such as agmatine. |
| US09884063B2 |
Amido-substituted azole compounds
The present invention relates to amido-substituted azole compounds of general formula (I), in which X1, X2, R1, R2, R4, R5, R7 and R8 are as defined in the claims which are inhibitors of TNKS1 and/or TNKS2, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients. |
| US09884060B2 |
KIF5B-RET fusion molecules and uses thereof
Novel RET fusion molecules and uses are disclosed. In one embodiment, a KIF5B-RET fusion includes an in-frame fusion of an exon of KIF5B (e.g., one or more exons encoding a kinesin motor domain or a fragment thereof) and an exon of RET (e.g., one or more exons encoding a RET tyrosine kinase domain or a fragment thereof). For example, the KIF5B-RET fusion can include an in-frame fusion of at least exon 15 of KIF5B or a fragment thereof (e.g., exons 1-15 of KIF5B or a fragment thereof) with at least exon 12 of RET or a fragment thereof (e.g., exons 12-20 of RET or a fragment thereof). |
| US09884057B2 |
Nonselective metabotropic glutamate receptor activators for treatment of attention deficit disorder and 22Q syndrome
This application relates to methods of treating attention deficit hyperactivity disorder (ADHD), 22q deletion and/or duplication syndrome, and co-morbidities with a nonselective activator of metabotropic glutamate receptors, such as fasoracetam, for example, in subjects having a genetic alteration in at least one metabotropic glutamate receptor (mGluR) network gene. |
| US09884049B2 |
Microbicidal composition comprising an octoxynol and a quinolizidine alkaloid compound or a source thereof
The present invention provides microbicidal compositions comprising an octoxynol and a quinolizidine alkaloid compound or a source thereof, and methods of using the compositions. The quinolizidine alkaloid compound has a structure: or a pharmaceutically acceptable salt, solvate or stereoisomer thereof. |
| US09884048B2 |
ERK inhibitors
The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are ERK2 inhibitors. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and a pharmaceutically acceptable carrier. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and an effective amount of at least one other pharmaceutically active ingredient (such as, for example, a chemotherapeutic agent), and a pharmaceutically acceptable carrier. |
| US09884045B2 |
Transplantation adjuvant in cell therapy using neural progenitor cells
The present invention provides a transplantation adjuvant for neural progenitor cells containing valproic acid and/or zonisamide as an active ingredient. |
| US09884044B2 |
Treatment using dantrolene
Provided are low-volume, safe for injection formulations of dantrolene yielding significant advantages over the currently approved and marketed dantrolene for malignant hyperthermia (MH) threatening anesthetic crisis. Once dantrolene can be made immediately available to patients triggered of MH, the anesthesiologist will be able to focus exclusively on the management of the patient's physiologic status in this complex and evolving crisis, not on the laborious and time consuming reconstitution process of the rescue agent. The low volume, safe for injection formulations of dantrolene have significant advantages over currently used approaches to the prevention and treatment of pumphead, and other neurological, cognitive and motor dysfunction incident to iatrogenically or trauma induced situations of altered blood flow, including those incurred during surgical procedures involving CPB or related procedures, as well as those incurred during non-normothermic episodes caused iatrogenically or by disease. |
| US09884041B2 |
Composition for the prevention or treatment of obesity, dyslipidaemia, fatty liver or insulin resistance syndrome, comprising piperonal as an active ingredient
Provided is a composition for the prevention or treatment of obesity, dyslipidaemia, fatty liver or insulin resistance syndrome, comprising piperonal as an active ingredient. The composition of the present invention can be used to advantage as a drug or functional food composition which not only exhibits activity in the prevention or treatment of obesity, hyperlipidaemia or fatty liver but which also causes a significant reduction in fasted blood sugar and blood insulin concentration and hence has an effect in improving Type-2 diabetes or insulin resistance and also improves metabolic disorder which is closely associated therewith. |
| US09884040B2 |
Desethylamiodarone for use in cancer treatment
The invention relates to a compound selected from the group consisting of desethylamiodarone and pharmaceutically acceptable salts, hydrates and solvates thereof, as well as pharmaceutical composition comprising the compound together with a pharmaceutically acceptable excipient, vehicle or carrier, for use in the treatment of cancer. |
| US09884032B2 |
Esters of short chains fatty acids for use in the treatment of immunogenic disorders
The present invention relates to short chain fatty acids (SCFA) for use in transmucosal administration to a subject for the prevention, attenuation or treatment of a disease or disorder associated with a compromised Th1 immune response and/or an unwanted Th2 or Th2-like immune response by modulating a Th2 immune response towards a Th1 immune response, particularly for the treatment, prevention and/or amelioration of viral infections and as an adjuvant for promoting the efficiency of vaccines and/or prevention of allergic diseases or disorders. |
| US09884031B2 |
Use of HDAC inhibitors for treatment of cardiac rhythm disorders
The present invention provides methods of ameliorating or reducing the extent of cardiac arrhythmia disorders, by administering an inhibitor of histone deacetylase enzyme (HDAC). |
| US09884025B2 |
Microspheres of pancreatic enzymes with high stability and production method thereof
The present invention refers to new microspheres including pancreatic enzymes, pharmaceutical compositions containing them, and a process to obtain them. The process here described doesn't involve the use of solvents and proves to be remarkably shorter and efficient than the producing methods of the prior arts. The microspheres obtained, including one or more pancreatic enzymes, one or more hydrophilic low-melting polymers and eventual excipients, have an high enzymatic activity, bio-availability and stability. |
| US09884022B2 |
Controlled release pharmaceutical compositions of tapentadol
A once daily controlled release pharmaceutical compositions comprising tapentadol, wherein preferably the mean Tmax of tapentadol is reached after 10 hours of administration of the composition. The composition comprises tapentadol, such that it maintains serum concentration of tapentadol of at least about 20 ng/ml for at least about 17 hours after oral administration of the composition. According to one embodiment the controlled release pharmaceutical composition comprises tapentadol, which is gastroretentive. |
| US09884021B2 |
Delayed release tablet with defined core geometry
A tablet comprising a core containing an active agent, and a coating, the core being disposed within the coating such that the coating has a thickness about a longitudinal axis (X-Y) of about 4.85 to 4.95 mm. The position of the core within the coating dictating that the active agent is released rapidly after a lag time during which time no active agent is released. |
| US09884012B2 |
Use of PEDF-derived polypeptides for promoting muscle or tendon regeneration or arteriogenesis
A method for promoting muscle or tendon regeneration, and/or arteriogenesis in a subject includes administering to the subject a pharmaceutical composition that contains a synthetic peptide, which has an amino acid sequence that has 20-39 amino acid residues and has at least 20 consecutive residues that has at least 90% amino acid sequence identity to residues 11-30 of SEQ ID NO: 1. The synthetic peptide may have the amino acid sequence of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 8, or SEQ ID NO: 9. |
| US09884001B2 |
Botulinum toxin in aerosol form and method of facial contouring using the same
The present invention provides a composition for facial contouring, comprising a mixture of botulinum toxin and air, and a method of facial contouring using the same. When the mixture of botulinum toxin and air is injected into an SMAS layer, the mixture strengthens the SMAS layer and draws back the galea aponeurotica to effectively lift up the face or change the facial contour, thus effectively enhancing the effect of facial contouring. |
| US09883999B2 |
Method for solubilizing rutin with polyhydroxy alkyl alcohols
The present invention generally relates to oral care compositions which enhance the solubility of rutin comprising rutin and at least one polyhydroxyalkyl alcohol. The present invention also relates to methods for use and manufacturing said oral care compositions. |
| US09883996B2 |
Methods and compositions for enhancing skin pigmentation
Described herein are methods and compositions useful for enhancing pigmentation, such as skin, eye and/or hair pigmentation comprising administering e.g., an NNT inhibitor or an agent that modifies redox status in a melanocyte. |
| US09883995B2 |
Oral care composition
Disclosed are oral care compositions, for example dentifrice compositions, comprising an oral care composition comprising an orally acceptable vehicle, metal oxide particles having an average particle size of no greater than a dentin tubule and at least one amino acid capable of chelating the metal oxide. The composition may comprise a polymeric adherent material for adhering the metal oxide particles in the dentin tubule. The metal oxide particles have a median particle size of 5 microns or less, and may comprise zinc oxide. |
| US09883994B2 |
Implementing organic materials in sunscreen applications
Techniques for implementing organic materials in sunscreen applications are provided herein. A method includes selecting a combination of multiple organic materials to incorporate into a sunscreen composition, wherein said selecting is based on (i) a desired absorption spectrum of the sunscreen composition, (ii) the absorption spectrum of each of the multiple organic materials, and (iii) a particle size limitation for each of the multiple organic materials, and incorporating the selected combination of organic materials into the sunscreen composition to generate the desired absorption spectrum. A composition includes a combination of multiple organic materials incorporated into a sunscreen composition, wherein the combination of organic materials is selected based on (i) a desired absorption spectrum of the sunscreen composition, (ii) the absorption spectrum of each of the multiple organic materials, and (iii) a particle size limitation for each of the multiple organic materials. |
| US09883993B2 |
Notch filter coatings for use in sunscreen applications
Notch filter coatings for use in sunscreen applications are provided herein. An exemplary composition includes multiple zinc oxide particles suspended within a medium forming sunscreen composition; and a combination of multiple notch filter coating materials individually applied as a distinct layer to each of the multiple zinc oxide particles to create a multi-layered structure surrounding each of the multiple zinc oxide particles within the sunscreen composition, wherein the multi-layered structure: reflects light at a user-determined wavelength range based on the wavelength range at which each of the multiple notch filter coating materials reflects light; and allows wavelengths of light (i) within at least a portion of the ultraviolet spectrum and (ii) outside of the user-determined wavelength range to be absorbed by the multiple zinc oxide particles. |
| US09883991B2 |
Alkyl sulfosuccinate mixtures, and use thereof
The invention relates to mixtures of alkyl sulfosuccinate monoesters of general formulas (I) and/or (II), in which R represents a linear or branched, saturated or unsaturated alkyl group having 6 to 22 C atoms, and X and Y independently represent a hydrogen atom or a cation that can form a water-soluble salt and is selected from among the group composed of alkali metal, alkaline earth metal, ammonia, and organic ammonia. The invention is characterized in that the mixture contains 30 to 70 percent by weight of C16 alkyl sulfosuccinate monoester and 30 to 70 percent by weight of C18 alkyl sulfosuccinate monoester, the percentages by weight being in relation to the total amount of alkyl sulfosuccinate monoesters of formulas (I) and (II). The invention also relates to the use of said mixtures in cosmetic and/or pharmaceutical preparations. |
| US09883990B2 |
Saline nose wipe and methods of manufacture and use
The present invention generally relates to a wet wipe or sheet that is suitable for contacting the skin and removing mucus from the skin. More specifically, the present invention relates to a wet wipe having an aqueous saline component suitable for dissolving and removing mucus in combination with the fabric matrix of the wet wipe. Typically, the fabric matrix of the wet wipe has a capacity of about 125 grams of solution per square meter, and it is impregnated with the aqueous saline solution to a level at or below approximately 80% of the absorbent capacity of the matrix. |
| US09883989B2 |
Stable dental varnish compositions and methods of manufacture and use
Fluoride varnish compositions for temporary application and adhesion to a person's teeth include a carrier that remains stable and translucent during storage. The compositions include a carrier comprising a stable and translucent resin and a fluoride ion source (e.g., a fluoride salt such as sodium fluoride) dispersed within the carrier so as to provide biologically available fluoride ions to teeth being treated. The carrier resists formation of solids that can plug a 25 gauge or smaller syringe brush applicator tip. The compositions may also include an adhesion promoting agent comprising an alkyl phosphoric acid. The composition adheres only temporarily to tooth tissue (e.g., for a period of at least about 4 minutes, but not more than about 1 year), after which the composition spontaneously wears away as a natural result of the action of the tongue, saliva and/or other factors. |
| US09883986B2 |
Standing bag type infusion liquid container
The present invention relates to a standing bag type container and aims to increase a visibility of the residual liquid volume in accordance with the progress of infusion process. The standing bag type container includes a bag 10 made of soft resin films and forming at its one end a base member 20 and an outlet port 18 at the other end of the bag. A suspension of the bag 10 is done in a manner that the base member 20 is located at the top. Marks for indication of residual liquid volume are printed on the surface of the bag. An infusion liquid is charged to the bag while an air gap 109′ is left, so that a residual liquid volume is verified from the liquid level. Under the suspended condition, the base member 20 has a value of width which is unchanged from the when the bag is under upright condition. The base member 20 is not collapsed and maintains its width even when the residual liquid volume is zero. A portion of the bag of a predetermined height from the top edge of the bag including the base member 20 maintains its shape without being collapsed by a discharge of the liquid. |
| US09883985B2 |
Combination cane and grabber device and a method for its use
The present cane and grabber device can comprise a cane component and a grabber component. The grabber component can be housed within the cane component or can be unsheathed from the cane component and utilized to grab one or more objects. In an embodiment, the cane component can provide support to a user both while housing the grabber component and while the grabber component has been unsheathed. In an alternative embodiment, one or more grabber components can be housed by a walker or other similar support providing device. |
| US09883977B1 |
Diaper with bowel pocket
A diaper insert has specifically configured contours on an inside surface to trap and contain bowel movements delivered within the diaper. An upper rear portion of the insert provides a protruding section of absorbent padding being contoured to match a lower lumbar region of the wearer. An upper front portion of the insert is provided with an additional absorbent pad to abut the abdominal area of the wearer. When a user, wearing a diaper equipped with the insert experiences a bowel movement, the padding sections contain the bowel movement within the diaper, and prevent the bowel movement from being secreted from a waist area of the diaper. In at least one (1) embodiment the insert is manufactured to be an integral portion of a diaper. In at least one (1) embodiment unitary rear and front barriers are removably added to a diaper. |
| US09883974B2 |
Disinfecting wound dressing and process for preparing such
A process for preparing a disinfecting wound dressing for the protection of wounds, such as burn wounds, ulcers and cuts, the process comprising the steps of providing a yarn-based substrate, subjecting a surface of the substrate to a plasma environment, thereby providing non-leaching and biocidal features to the substrate surface by exposing the substrate surface to an antimicrobial active compound reaction. |
| US09883973B1 |
Fiber Bragg Grating hearing device
A movement and expression sensor has a plurality of fiber Bragg gratings (FBG) disposed along the length of an optical fiber, and the optical fiber is placed in contact with a subject's skin surface. The sensors are interrogated for reflected wavelength, which is converted into a temperature or a strain. A series of such measurements can be made to determine the movement or position of the sensor location. A garment may be formed using the sensors and an elastomeric material, such that the sensors may be worn and removed, and the movements of the elastomer in the areas of sensors measured as a wavelength shift to characterize movement or estimate location. The elastomeric garment may be formed as a mask, or a sock, such as for use with a face, or foot. |
| US09883970B2 |
Real time acoustic dosimetry for corneal collagen crosslinking
A change in the response of the cornea to ultrasonic energy directed into the cornea is monitored during irradiation of the cornea to bring about corneal crosslinking. Because the change in ultrasonic response is correlated with the degree of crosslinking achieved, a desired degree of crosslinking can be achieved by terminating the irradiation when the change reaches a threshold. The change in ultrasonic response can be determined by taking a baseline measurement before irradiation and additional measurements during irradiation using the same ultrasonic transducer (47). The transducers may be carried on a device (30) resembling a contact lens which overlies the eye and which transmits the light used in the irradiation step to the eye. |
| US09883969B2 |
Intrascleral shunt placement
Glaucoma can be treated by implanting an intraocular shunt into an eye. The eye has an anterior chamber and sclera. A shunt can be placed into the eye to establish fluid communication from the anterior chamber of the eye through the sclera. |
| US09883968B2 |
Fluid exchange apparatus and methods
An injector apparatus comprises an elongate structure having one or more openings positionable near a penetrable barrier of an implantable device so as to receive fluid of the implantable device. The apparatus comprises a needle and a sheath extending over at least a portion of the needle. The elongate structure may comprise a distal tip to penetrate tissue and the penetrable barrier, and a distal opening near the tip to release therapeutic fluid into the implantable chamber. In many embodiments the distal tip, the distal opening, and the plurality of openings are separated from a stop that engages a tissue of the patient and limit penetration depth such that the distal opening and the plurality of openings are located along an axis of the implantable device to increase an efficiency of the exchange. |
| US09883966B2 |
Flexible spout improvement for a disposable urinal
A urinal includes a urinal body, a urine receiving reservoir and a spout extending therefrom for receiving urine. A supplemental urinal spout is provided and comprises both an inlet portion and a retention portion, the supplemental urinal spout being attachable to the spout of the urinal to form a leak prevention seal. Opposing tabs are provided to aid in attaching the spout to the urinal. The supplemental urinal spout comprises a funnel-shaped element that is integrally formed with a cylindrical sidewall. The urinal body is preferably made of a plastic material and the supplemental urinal spout is made from a low durometer elastomeric material. The urinal and the supplemental urinal spout may be disposable. |
| US09883963B2 |
Modular orthosis system and kit for the fitting thereof
Provided are systems and methods relating to a modular orthosis system for an orthosis of the lower extremity, which modular orthosis system simplifies an individual fit to the respective patient and his loss of function, and, during the course of the therapy, can be fitted with direct consultation of the patient to changed circumstances in an interdisciplinary manner. A particular exemplary advantage of the orthosis system is that the therapist, together with the patient, can test the position of the support spring (dorsal vs ventral, medial vs lateral) and also different spring strengths. Thus, the orthosis can be fitted to the patient in a simple manner. |
| US09883962B2 |
Stent delivery system
An operating unit constituting a stent delivery system is provided with a first rotary roller having a first gear and a second rotary roller having a second gear. The first gear is meshed with a first tooth portion of a rack member and the second gear is meshed with a second tooth portion of the rack member. The first gear is formed to have a large diameter relative to the second gear and at the time of releasing a stent, after positioning a distal end of an outer tube body close to the stent through the rack member with the rotation of the first rotary roller of the operating unit, it is possible to move the outer tube body toward a proximal side at a lower speed than that in the previous state with the rotation of the second rotary roller. |
| US09883958B2 |
Stent delivery device
A stent delivery device has a handle and a sliding body, the sliding body is slidable with respect to the handle. The handle has a grip and a guide. The sliding body has at least two flange portions extending from the sliding body. The flange portions are offset from one another along the length of the sliding body. The operator can thereby deploy a relatively long stent by first gripping the nearest flange portion and pulling the sliding body toward the handle; subsequently, the operator can reposition his/or finger on the next-nearest flange portion and continue deployment of the stent by pulling the sliding body further toward the handle. |
| US09883954B1 |
Acetabular template component and method of using same during hip arthrosplasty
A medical imaging device takes one or more images of the local anatomy of a patient undergoing a surgical procedure. A surface model generator receives the one or more images and generates a 3-D surface model of the patient's anatomy. A fabrication device utilizes the 3-D surface model to fabricate a template custom designed to match the surface of the patient's anatomy. Attached to the template is a directional guide vane. The fabrication device is configured to create a template and directional guide vane such that, when the template is fitted to the patient's anatomy, the directional guide vane points along a predefined orientation relative to the patient's anatomy. A physician uses the directional guide vane as a visual guide or cue for installing an implantable prosthetic component during a surgical procedure. |
| US09883952B2 |
Spinal construct and method
A spinal construct includes a first endplate that is configured to engage a first vertebral surface. An expandable member is connected with the first endplate and includes a mating element. A second endplate is configured to engage a second vertebral surface and includes an in-situ guide surface engageable with the mating element to connect the member with the second endplate. Systems and methods are disclosed. |
| US09883948B2 |
Adjustable height arthroplasty plate
An orthopaedic assembly. The orthopaedic assembly includes a first member adapted to be coupled to a bone and an adjustable connector assembly including an adjuster having a threaded end and a tapered end. The assembly also includes an articulation component including a bearing surface and adapted to be coupled to the tapered end of the adjustable connector assembly. The threaded end is adapted to engage the fixation plate. |
| US09883946B2 |
Composite prosthetic surfaces
A composite article (e.g., prosthesis) and method of preparing the article is provided. An article may include a body having a matrix of a first hardness having a plurality of particles of a second hardness embedded in the matrix in fixed locations, the second hardness being harder than the first hardness, and the matrix having an external wear surface with a portion of the particles being proximal to or exposed at the external wear surface. The matrix with the particles may improve the life and durability of the article. |
| US09883943B2 |
Implantation of repair devices in the heart
Apparatus is provided, including a plurality of helical tissue anchors and an intracardiac annuloplasty structure defining a plane for placement on a heart valve annulus. The annuloplasty structure includes a plurality of compressible subunits, and a plurality of anchor mounts alternately disposed with respect to the plurality of compressible subunits. Each anchor mount (a) defines at least one opening for passage therethrough of a respective helical tissue anchor, (b) defines a path for passage therethrough of the helical tissue anchor, the path being aligned along an axis that is at a non-zero angle with respect to the plane of the annuloplasty structure, and (c) provides a structural element in the path for corkscrewing a distal portion of the helical tissue anchor therearound. Other embodiments are also described. |
| US09883939B2 |
Reducing immunogenicity of xenogeneic transplant tissues
Methods of preparing and porcine cells, organs and tissues that have reduced immunogenicity, e.g., for transplant into humans, e.g., for the treatment of burn injuries. |
| US09883937B2 |
Method and apparatus for treating urethral stricture
A method of delivering a therapeutic device to a treatment area of a body lumen, the therapeutic device including a) a delivery member possessing at least one attachment part and b) a treatment membrane, includes wrapping the treatment membrane on the delivery member, attaching the treatment membrane to the attachment part of the delivery member, and moving the delivery member toward the treatment area, detaching the treatment membrane from the delivery member, and withdrawing the delivery member from the body lumen. |
| US09883936B2 |
Atrial appendage blood filtration systems
Instrumentation for percutaneous delivery of blood filtration devices to atrial appendages includes a curved access sheath and a delivery tube. A compressed filter device attached to a tether wire is loaded in the delivery tube. The access sheath and the delivery tube can be mechanically locked and moved together to place the device in a suitable deployment position. The device is deployed by expelling it from the delivery tube either by retracting the delivery tube over the tether wire, or by moving the tether wire forward through the delivery tube. A filter membrane in the deployed device extends across the appendage ostium to filter blood flow through the ostium. The filter membrane is configured to present a flat surface to atrial blood flow past the ostium. |
| US09883935B2 |
Process for preparing hernia mesh from monofilament
The present invention relates to a monofilament with a segmented pie structure formed by conjugated spinning of degradable polymers and non-degradable polymers, a hernia mesh having improved flexibility and biocompatibility, and a preparation method of the monofilament. More specifically, the hernia mesh of the present invention having improved flexibility and biocompatibility is prepared using the monofilament obtained by conjugated spinning of degradable polymers and non-degradable polymers into a segmented pie form, to control it to be gradually degraded in the body, whereby the stiffness of the early stage is removed, and thereby the foreign body sensation is also removed. |
| US09883934B2 |
Mechanical anal incontinence apparatus
An anal incontinence treatment apparatus with an adjustable restriction device implanted in a patient, who suffers from anal incontinence. The device engages a portion of the colon or rectum of the patient to restrict the fecal passageway. A hydraulic adjustment device adjusts the restriction device to restrict or release the fecal passageway, i.e. to normally close the fecal passageway and open the fecal passageway when the patient wants to relieve himself or herself. |
| US09883933B2 |
Medical device and method of delivering the medical device
The invention discloses an implant. The implant may include a first flap and a second flap. The first flap may further include a first portion, a second portion and a transition region. The first portion may be configured to be attached proximate a sacrum. The second portion may be configured to be attached to an anterior vaginal wall. The transition region lies between the first portion and the second portion. The second flap may be fabricated such that a portion of the second flap is configured to be attached to a posterior vaginal wall. The implant may be configured such that a value corresponding to a biomechanical parameter defining a biomechanical attribute of the portion of the first flap attaching to the anterior wall is different from a value of the biomechanical parameter defining the biomechanical attribute of the portion of the second flap attaching to the posterior wall. |
| US09883930B2 |
Method for using plasma-treated liquid
A method comprises: bringing a plasma-treated liquid having an oxidizing power into contact with an object in an area; and mixing water and the plasma-treated liquid which remains in the area after the plasma-treated liquid is brought into contact with the object. |
| US09883929B2 |
Dental superstructure, and method of manufacture thereof
A dental superstructure with integrated spacers including a main body and at least one integrated spacer. The superstructure is intended to be connected to the at least one osseointegrated dental implant through connection between the integrated spacer and the osseointegrated dental implant. A manufacturing method thereof is also provided. |
| US09883928B2 |
Dental articulator
A dental articulator apparatus and method of forming dental casts utilizing a dental articulator having pivotally connected upper and lower arms that each have a ball socket which receives a ball at the outer end of a respective model anchor, the opposed end of which is cast into a dental model. The model anchor ball is adjustably secured in the ball socket of the articulator arms by a set screw coupled with a rotatable magnetic extension rod that are installed, removed, advanced, and retracted as a unit and allow relative rotation between the set screw and the extension rod to facilitate fitting and positioning the ball in the socket when the set screw is loosened, and eliminate manually installing and positioning separate small shims and plungers that can be accidentally dropped and lost. |
| US09883921B2 |
Changeable positioning device for dental drilling
A changeable positioning device for dental drilling comprises a base, a guide body and a positioning block. The base comprises a top end, a bottom end, a first outer wall, a first inner wall, a first guide groove, at least one first recess and at least one second recess. The at least one protrusion can be slidably fitted with the at least one first recess and the at least one second recess, thereby the second guide groove of the guide body will not be synchronously moved with a drill during drilling toward the axial direction of the guide body. The distance between the two extension portions is smaller than the diameter of the second inner wall at the same plane that is perpendicular to the axis of the guide body so that the drill will not deviate from the guide groove, thereby increasing the stability and precision of drilling. |
| US09883917B2 |
Skin dilator
Disclosed is a skin dilator, comprising an expander (11), a pipe network provided on the skin-side surface wall (111) of the expander (11) composed of longitudinal tube (22) and horizontal tube (21) having a reticular structure and communicating with each other, and a guide tube (24) communicating with the pipe network. The skin dilator further comprises several burrs (25) distributed on the skin-side surface wall (111) of the expander (11), and several small apertures (23) communicating the inner cavity of the tube with the outside are provided on both of the longitudinal tube (22) and horizontal tube(21). The tissue expander can be infused biological agents by the filling port to the skin expanding site through the small apertures (23), which may accelerate the expansion growth of skin, prevent skin complications, such as necrosis. |
| US09883915B2 |
Instrument actuation process
A system includes a medical instrument that includes a termination fixture, an actuated element, and drive members coupled to the actuated element and extending to the termination fixture. The termination fixture provides an interface that exposes portions of the drive member to direct movement by an external system that may include a manipulator and a sterile barrier. |
| US09883912B2 |
Suspension system for minimally invasive surgery
A suspension system for supporting surgical devices inside a patient's body cavity comprising an external frame, a plurality of elongated members extending from the external frame and through the patient's skin into the body cavity, and an internal platform located inside the body cavity. The internal platform includes a plurality of links reconfigurable from a first elongated position wherein the links are substantially aligned along a longitudinal axis for insertion to a second position wherein the links are angled with respect to one another to form a non-linear configuration. A first support of the external frame is movable with respect to the second support to thereby move the internal platform. |
| US09883905B2 |
Electrosurgical probes for suction and irrigation systems
An electrosurgical probe for suction and irrigation systems is provided. The electrosurgical probe comprises an elongate tube with a probe tip and a probe handle. An unobstructed fluid communication path is defined by the probe handle and elongate tube. |
| US09883903B1 |
Systems and methods for analyzing an electrosurgical unit
Systems and methods for analyzing an electrosurgical unit are provided. One system includes an electrosurgical unit analyzer having an input configured to receive radio frequency (RF) signals from an electrosurgical generator and a measurement subsystem configured for programmable waveform detection corresponding to the received RF signals. The measurement subsystem includes a field-programmable gate array (FPGA) defining one or more thresholds for the waveform detection. The electrosurgical unit analyzer further includes a user interface displaying information relating to individual pulses detected from the RF signals. |
| US09883902B2 |
Surgical device with improved mains module
A surgical device having a step-up converter, a power supply unit and a control arrangement. The step-up converter converts a mains AC voltage to an intermediate circuit voltage and energizes a DC intermediate circuit. The power supply unit includes an inverter connected to the intermediate circuit. The power supply unit also includes a transformer that has a primary coil connected to the inverter and a secondary coil for energizing a load. The control arrangement includes a PFC control circuit connected in a controlling manner to the step-up converter. The control arrangement further includes an operation control circuit connected in a controlling manner to the power supply unit. The PFC control circuit and operation control circuit are connected to each other via a digital communication interface. |
| US09883900B2 |
Method of operating a medical cooling system
A method of operating a medical system, including coupling a medical system to an outlet of a fluid distribution network having a plurality of fluid outlets in a patient treatment center; delivering fluid from the outlet to the medical system; compressing the delivered fluid with the medical system; decreasing the moisture content of the delivered fluid with the medical system; cooling the fluid with the medical system; delivering the fluid from the medical system to a medical device; and removing the fluid from medical device with the medical system. |
| US09883898B2 |
Pedicle screw with electro-conductive coating or portion
A pedicle screw may include an electrically conductive portion formed from a material having a greater electrical conductivity than that of the base material from which the screw is formed. The electrically conductive portion preferentially channels electrical energy supplied by an electrical probe to a location of the electrically conductive portion facing the nerve root. The portion thus provides a sort of electrical highway that helps to focus the electrical energy applied to the pedicle screw in a particular direction, towards the presumed location of the nerve root. As an alternative to placement of the electrically conductive portion in the pedicle screw itself, the electrically conductive portion could be placed within a tap that is used in preparing the pedicle for receipt of the pedicle screw (e.g., in forming the threaded structure in the pedicle bone into which the pedicle screw will then be placed). |
| US09883897B2 |
Method and apparatus for a compressing plate
An orthopedic bone plate constructed from shape memory material provides the ability to move from an open shape to a compressed shape and create compression on two bones or bone fragments to encourage healing. The plate may be any umber of shapes, with two or more screws anchoring the plate to bone. The plate is affixed to bone in a sequence of steps that involve first placing the plate on an insertion tool, attaching drill guide tubes, placing the plate over bone, drilling holes in bone, and then attaching the plate to the bone via screws. The insertion tool can then be removed at the surgeon's convenience allowing compression on the two bones. |
| US09883895B2 |
One way sliding device for intramedullary intertrochanteric fixation implants
A device for treating fractures, comprises an intramedullary member sized and shaped for insertion along a longitudinal axis of a bone within a medullary canal thereof, the intramedullary member including an opening extending obliquely therethrough, the opening, when the intramedullary member is in a desired position within a bone, aligning with a desired axis along which an implant is to be inserted into a bone, the intramedullary member including a channel formed therewithin and opening to the opening and a locking mechanism mounted in the channel, the locking mechanism including a locking abutting structure extending into the opening in combination with an implant sized to be slidably received through the opening and inserted along the desired axis, the implant including a plurality of implant abutting structures aligned to engage the locking abutting structure preventing medial movement of the implant relative to the intramedullary member. |
| US09883893B2 |
Anterior cervical instrumentation systems, methods and devices
Anterior cervical instrumentation systems, methods, and devices are disclosed. Systems may facilitate immobilizing or providing support for the cervical portion of the vertebral column of a patient. A device may comprise a plate having two channels located in a proximal to distal direction, and may further comprise at least one aperture. The device may further comprise attachment elements such as attachment cross-links and spacer cross-links, and fasteners. The plate and the attachment elements may be secured to the vertebrae by passing fasteners through apertures and channels. The length of the plate, position and number of the attachment cross-links, position and number of spacer cross-links and degree of movement may be intraoperatively selected by the surgeon to provide an optimal application and procedural outcome. Uniform components of the devices and systems allow for a more streamlined and simplified method of treating spinal conditions. |
| US09883891B1 |
Spinal fixation method and apparatus
A spinal stabilization system having a pedicle screw which includes (i) a shaft with external threads and a head segment on one end of the shaft; (ii) a first drive socket positioned in the head segment; (iii) a second drive socket on a shaft end opposite the first drive socket; and (iv) wherein the shaft end opposite the first drive socket has a lesser diameter than the shaft end at the head segment. The system further includes an intervertebral stabilization structure having an elongated body with rotating ring segments attached to each end of the elongated body. |
| US09883884B2 |
Ultrasonic surgical instruments
A surgical instrument configured to be coupled to a transducer configured to produce vibrations. The surgical instrument comprises an end effector comprising an ultrasonic blade, a protective sheath, and outer tube and an aperture. The ultrasonic blade extends along a longitudinal axis of the end effector and is configured to be coupled to a transducer. The protective sheath extends at least partially around the ultrasonic blade. The outer tube extends at least partially along the longitudinal axis. The aperture defines a channel extending at least partially through the end effector along the longitudinal axis. |
| US09883881B2 |
Motor driven surgical instrument with fluid control circuit
A surgical system includes a surgical tool having a motor with a shaft configured to rotate, a cutting device that reciprocates in accordance with the rotation of the shaft, and a position sensor that determines a state of the motor and outputs a position signal representing the motor state. A fluid regulator provides fluid to the motor, and the motor rotates in accordance with the fluid provided. A controller generates a fluid flow command based at least in part on the position signal. The fluid regulator receives the fluid flow command and regulates fluid flow to the motor accordingly. |
| US09883877B2 |
Systems and methods for removal of blood and thrombotic material
A system for aspirating thrombus includes a catheter having a supply lumen having a distal end and an aspiration lumen configured to couple to a vacuum source and having an interior wall surface and an open distal end, an orifice at or near the distal end of the supply lumen, in fluid communication with the interior of the aspiration lumen, the orifice located proximally of the open distal end of the aspiration lumen, wherein the orifice is configured to create a spray pattern that impinges on the interior wall surface of the aspiration lumen when a distal end of the aspiration catheter is immersed within an aqueous environment, and a disposable tubing set having a first conduit configured to couple the supply lumen of the aspiration catheter to a fluid source, and a pump component associated with the first conduit and configured to detachably couple to a drive unit. |
| US09883872B2 |
Adjustable reaming device having a discretely positionable stop element
An adjustable reaming device can include a proximal reamer and a positionable element. The positionable element removably attaches to the proximal reamer at one of a plurality of discrete longitudinal locations along the proximal reamer. A distal end of the positionable element forms a stop, which can contact a proximal end of a distal reamer and thereby limit distal motion of the proximal reamer with respect to the distal reamer. When the distal reamer is in contact with the positionable element, the distal reamer and proximal reamer are longitudinally offset by a one of a plurality of specified offsets. In some examples, the specified offsets correspond to a plurality of specified, discrete lengths for which implantable femoral stems are available. |
| US09883869B2 |
Tool head assembly and associated apparatus
A tool head assembly for a hand held tool The assembly includes a body for attaching to the hand held tool; a continuous cutting band having a cutting edge for cutting into a subject; at least one tension member coupled to the body for holding the cutting band under tension; and at least one drive member coupled to the body for rotating the cutting band with respect to the body. |
| US09883866B2 |
Clips and applicator for tissue closure
Surgical clips and surgical applicators used in performing rapid tissue closure in either minimally invasive surgeries or traditional open procedures are provided. In one example approach, a surgical clip comprises opposing sides extending from a top portion and terminating at tips positioned below the top portion. The resting position of the clip is its closed position. Edges of the top portion and the opposing sides form opposing faces perpendicular to the opposing sides. The opposing faces are angled inwardly towards each other at a region of the faces adjacent to the top portion. Grooves are formed in each of the opposing sides. The grooves are configured to engage inwardly turned tracks of a clip applicator such that, when a force is applied to the clip, the opposing sides bend outwardly away from each other to place the clip in an intermediate open position. |
| US09883864B2 |
Medical device for modification of left atrial appendage and related systems and methods
Devices, methods and systems are provided for occluding an opening within the tissue of a body, such as a left atrial appendage. In one embodiment, a system for use in occluding an opening in the tissue of a body includes a handle, a catheter coupled with the handle and a medical device disposed within a lumen of the catheter. The medical device includes an anchor system having a plurality of anchor segments coupled with an anchor hub. The medical device further includes an occluder system having a plurality of occluder segments coupled with an occluder hub. A first actuator is configured to displace the occluder hub independent of, and relative to, the anchor hub to deploy the occluder system from a retracted state to an expanded state while the anchor system remains in a retracted state. |
| US09883862B2 |
Stapler for mucosectomy
The head of a stapler for mucosectomy comprises an external goblet-shaped body (1) wherein an internal goblet-shaped body (2) is concentrically and slidingly located, at the edge of which a circular blade (3) is fixed. The internal goblet-shaped body (2) is provided with a central hole (5) wherein a rod (6) is slidingly inserted, at the end (7) of which an anvil (8; 8′) is fixed. One or more annular grooves (11), which are parallel and suitably spaced one from the other, are formed on the lateral surface of the rod (6) perpendicularly to the axis thereof. Said grooves (11) are intended to receive a portion of mucosa (9a) which is included in a purse string suture as the mucosa is tied around the rod (6). By retracting the rod (6) in the central hole (5) of the stem (2a) of the Internal goblet-shaped body (2) the mucosa to be removed is carried into the internal goblet-shaped body (2). The anvil (8; 8′) and the circular blade (3) are moved closer one to the other, by suitable means, in order to cut the tissues when the stapler is in a closed position. |
| US09883861B2 |
Retainer assembly including a tissue thickness compensator
A retainer for assembling tissue thickness compensators to a surgical stapler can comprise a grip, a first surface for supporting a first tissue thickness compensator, a second surface for supporting a second tissue thickness compensator, and clips for aligning and attaching the retainer to the surgical stapler. The clips may align and attach the retainer to a staple cartridge of the surgical instrument. The clips may align the retainer with an anvil of the surgical instrument. An insertion tool may be used in combination with the retainer to insert the retainer into the surgical stapler and to push the tissue thickness compensators against the anvil and/or the staple cartridge of the surgical instrument. |
| US09883860B2 |
Interchangeable shaft assemblies for use with a surgical instrument
An interchangeable shaft assembly for use with a surgical instrument. The surgical instrument may include a frame that operably supports a plurality of drive systems and defines an actuation axis. The shaft assembly may comprise a first shaft that is configured to apply first actuation motions to a surgical end effector that is operably coupled thereto. A proximal end of the first shaft is configured to be operably releasably coupled to a first one of the drive systems supported by the frame in a direction that is substantially transverse to the actuation axis. |
| US09883859B2 |
Flexible suture anchor threader and suture anchor kit
A suture anchor kit includes an anchor body having a central bore extending from an opening at a proximal end of the anchor body through a portion of the length thereof. A transverse member is disposed in the central bore such that the ends of the transverse member extend across the bore to the anchor body. A suture anchor threading apparatus may have a handle and a suture threader extending from the handle. The suture threader has a wire loop open sufficiently to accept at least one suture and is made of an elastic material having a resiliency sufficient to bend 120° to 180° about a 1 mm to 4 mm radius without permanent deformation. |
| US09883857B2 |
System for providing surgical access
One embodiment is directed to a system for closing a wound created across a portion of a tissue structure, comprising a suture member having proximal and distal ends; an anchor member coupled to the distal end of the suture member; a tension retainer assembly releasably coupleable to the suture member; and a suture buttress movably intercoupled to the suture member between the anchor member and the tension retainer and configured to minimize direct sliding contact between the suture member and the tissue structure portion around the location of the suture buttress. |
| US09883856B2 |
Systems and methods for treatment of perforator veins for venous insufficiency
Systems and methods for the treatment of perforator veins for venous insufficiency are described. The systems can include a catheter assembly comprising a proximal hub, a spin lock on the proximal hub, a elongate body overmolded to the proximal hub, and a distal end, the catheter, the elongate body configured to be placed within a perforator vein; an extension tubing having a proximal female hub, a distal male hub, and an elongate body therebetween, the distal male hub having a spin lock thereon, the distal male hub configured to be attached to the proximal hub of the catheter assembly; a syringe filled with a volume of media including cyanoacrylate; and an injector configured to automatically dispense a bolus of the media sufficient to coapt the perforator vein from the syringe upon actuation of a control on the injector. Methods are also disclosed. |
| US09883855B2 |
Apparatus and method for heart valve repair
A device 10 for gathering tissue of a heart valve leaflet 2 may include an outer tube 16 extending in an elongation direction, a capture tool 22 moveable in the outer tube between a contained position and a use position, and a tissue securing component 32 disposed at a distal end 17 of the outer tube and adapted to be applied to tissue 8 captured by the capture tool to hold the captured tissue in a gathered configuration. The capture tool may include a first element 20 and a second element 22 that are moveable relative to one another in the elongation direction. The first and second elements 20, 22 may be operable to capture tissue 8 of the heart valve leaflet 2 therebetween and to draw the captured tissue into the outer tube 16 in the gathered configuration. |
| US09883852B2 |
Ultrasound systems, methods and computer program products for estimating tissue deformation with harmonic signals
An ultrasound system for estimating tissue deformation in ultrasound elasticity imaging includes a controller configured to deliver a plurality of tracking pulses and to obtain a plurality of data sets for a region of interest from an ultrasound transducer array; a harmonic data analyzing circuit configured to receive the plurality of data sets and to extract one or more harmonic data sets including harmonic signals from the plurality of image data sets; and a displacement estimator circuit configured to estimate tissue deformation in the region of interest responsive to the one or more harmonic data sets. |
| US09883848B2 |
Ultrasound imaging using apparent point-source transmit transducer
An apparent point-source transmit transducers comprises a substantially constant-thickness shell of piezoelectric material in a shape of a spherical-section. Such transducers may be sized such that a single apparent point-source transmit transducer may produce ultrasound waveforms with substantial energy in a medium to be imaged. Use of such transducers in three-dimensional ping-based imaging may permit deeper and higher quality imaging than may be possible with conventional transducers. |
| US09883845B2 |
Radiographic apparatus and tomographic apparatus
A radiographic apparatus includes a radiation source that emits radiation, a radiation detection unit that detects the radiation emitted from the radiation source, and having transmitted the object of a subject to be examined, a holding unit that holds the object to be examined between the radiation source and the radiation detection unit, and a control unit that performs control for determining an imaging condition, based on information related to the posture of the subject. |
| US09883840B2 |
Dynamically scanned x-ray detector panel
An x-ray imaging system for imaging a subject includes an x-ray source configured to project an x-ray radiation toward a portion of the subject and a panel detector positioned opposite the x-ray source relative to the subject and configured to receive x-ray radiation passing through the subject. The panel detector includes a scintillation layer converting x-ray radiation to light rays of a selected spectrum and a plurality of microelectromechanical scanners. Each microelectromechanical scanner includes a photodetector mounted on a corresponding movable platform and configured to detect light in the selected light spectrum. The panel detector includes a scanning control module configured to move each platform in a selected scan pattern. |
| US09883834B2 |
Medication delivery device with multi-reservoir cartridge system and related methods of use
A medication delivery system for delivering medicament to a body of a user. The medication delivery system may include a housing having a plurality of medicament reservoirs therein, a first sensor configured to continuously monitor a parameter of the body, and a pump mechanism configured to pump medicament from each of the plurality of medicament reservoirs to a delivery mechanism having a portion disposed within the body of the user. |
| US09883829B2 |
Bodily fluid composition analyzer with disposable cassette
Disclosed is an apparatus for analyzing the composition of bodily fluid. The apparatus can include a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient and a pump unit in operative engagement with the fluid handling network. The pump unit can have an infusion mode, in which the pump unit is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode, in which the pump unit is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus can include a spectroscopic analyzer positioned to analyze at least a portion of the sample; a processor in communication with or incorporated into the spectroscopic analyzer; and stored program instructions executable by the processor to obtain measurements of two or more properties of the sample. |
| US09883828B2 |
Test element and test system for examining a body fluid
The invention relates to a test element as a single-use article for examining a body fluid, comprising a lancing member that can be inserted into a body part, a collecting area configured thereon for body fluid obtained by the lancing and at least one light guide for an optical measurement in the collecting area. The collecting area is formed by a collection recess of the lancing member which extends in the lancing direction and the light guide is integrated into the lancing member such that it is secure against displacement and the distal end thereof is arranged in a proximal measurement zone of the collection recess. |
| US09883825B2 |
Living body optical measurement apparatus, living body optical measurement method, and engagement member for mobile position sensor
A living body optical measurement apparatus of the present invention includes: a light irradiation/measurement unit for irradiating light to an object and measuring the light passed through the object, a signal processing unit for processing measurement data of the light irradiation/measurement unit and creating a living body optical measurement image, and a position measurement unit for measuring positions where light is irradiated to an object and where the passing light is extracted from the object, the light irradiation/measurement unit includes plural optical fibers. The light irradiation/measurement unit includes plural optical fibers, plural optical fiber plugs attached to the plural optical fibers respectively, and a holder fixed detachably at a measurement site of an object and holds the plural optical fiber plugs. The position measurement unit includes a mobile position sensor and an engaging member having a shape detachably engaged with the plural optical fiber plugs attached to the mobile position sensor and held in the holder. |
| US09883824B2 |
Detecting device
A detecting device includes at least one detecting module. In the detecting module, a light source unit is configured to emit a first beam and a second beam. The wavelength of the first beam is different from that of the second beam. A packaging unit is disposed on the light source unit and a light detecting unit and on transmission paths of the first beam and the second beam from the light source unit. An optical microstructure unit is disposed on the transmission paths of the first beam and the second beam. The first beam and the second beam emitted from the light source unit pass through the packaging unit to pass the optical microstructure unit to be transmitted to a biological tissue, and then pass through the optical microstructure unit to pass the packaging unit to be transmitted to the light detecting unit in sequence. |
| US09883822B2 |
Biometric sensor chip having distributed sensor and control circuitry
A sensor includes a sensor array formed on a first side of a substrate and at least one circuit operative to communicate with the sensor array formed on a second side of the substrate. At least one via extends through the substrate to electrically connect the sensor array to the at least one circuit. Placing the at least one circuit on the second side of the substrate allows the sensor array to occupy substantially all of the first side of the substrate. |
| US09883819B2 |
Ingestion-related biofeedback and personalized medical therapy method and system
Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis. |
| US09883818B2 |
Fiducial localization
Fiducial localization methods and apparatus are described. |
| US09883817B2 |
Management, assessment and treatment planning for inflammatory bowel disease
Discussed herein is an image processing device and a corresponding method for assessing inflammatory bowel diseases. A plurality of dynamic MRI sequence of images of a bowel that include peristalsis information of the bowel and static MRI image(s) of the bowel that identify at areas of inflammation, stenosis, and increased mural thickness of the bowel are processed. A displacement of the bowel caused by respiration of the patient is conducted on the dynamic MRI sequences by performing a non-rigid registration. A peristaltic activity is determined by performing motion flow analysis on the dynamic sequences of images. A peristaltic activity of the static MRI image(s) based on a weighted sum of two closest dynamic MRI sequences of images is computed and the static image is combined with the closest dynamic MRI sequence of images by performing a multi-modal registration. |
| US09883816B2 |
Eyewear
A technique to detect an eye potential of a wearer of an eyewear by using an electrode abutting on the glabella of the wearer has been known, but it is desirable to surely cause the electrode to abut on the glabella so as to prevent deterioration in the detection accuracy of detecting a biosignal indicating an eye potential, myogenic potential, brain wave or the like. In view of this, an eyewear including: a frame; a first electrode that abuts on a glabella of a wearer of the eyewear; and an electrode holding unit that holds the first electrode such that a distance between the frame and the first electrode is changeable is included. |
| US09883812B2 |
Enhanced multi-core beamformer algorithm for sensor array signal processing by combining data from magnetoencephalography
Techniques and systems are disclosed for implementing multi-core beamforming algorithms. In one aspect, a method of implementing a beamformer technique includes using a spatial filter that contains lead-fields of two simultaneous dipole sources rather than a linear combination of the two to directly compute and obtain optimal source orientations and weights between two highly-correlated sources. |
| US09883807B2 |
Object information acquiring apparatus and control method therefor
An object information acquiring apparatus includes a probe configured to detect a photoacoustic wave generated from an object irradiated with light, a signal collector configured to generate a first detection signal from the photoacoustic wave, a signal processor configured to generate, from the first detection signal, a second detection signal in which a component having a phase inverted from the phase of a component deriving from the photoacoustic wave is reduced, by using a differential signal of an impulse response of the probe, and an image generator configured to generate image data on the inside of the object using the second detection signal. |
| US09883802B2 |
Measurement probe
A measurement probe is configured to be detachably connected to an optical measurement apparatus for optically measuring a living tissue and includes: an illuminating fiber configured to apply illumination light to the living tissue; a plurality of light receiving fibers configured to receive, at different positions, the backscattering light which is applied by the illuminating fiber and backreflected and/or backscattered from the living tissue; and a support section that is substantially cylindrical and configured to make a distance from each distal end of the illuminating fiber and the plurality of light receiving fibers to the living tissue constant, and permit the illumination light to pass through at least a part of a side surface thereof. An illumination area of the illumination light applied by the illuminating fiber on the living tissue is larger than the area of a distal end of the support section. |
| US09883799B2 |
Method of identifying when a patient undergoing hemodialysis is at increased risk of death
The invention is directed to a method of identifying a patient undergoing periodic hemodialysis treatments at increased risk for death that includes determining at least one of the patient's clinical or biochemical parameters, including systolic blood pressure, serum albumin concentration level, body weight, body temperature, serum bicarbonate concentration level, serum potassium concentration level, serum calcium concentration level, hemoglobin concentration level, serum phosphorus concentration level, neutrophil to lymphocyte ratio, equilibrated normalized protein catabolic rate (enPCR), equilibrated fractional clearance of total body water by dialysis and residual kidney function (eKdrt/V), EPO resistance index, transferrin saturation index, serum ferritin concentration level, serum creatinine concentration level, platelet count, Aspartat-Aminotransferase level, and Alanin-Aminotransferase level at periodic hemodialysis treatments, and identifying a patient as having an increased risk for death if the patient has a significant change in the rate of change of at least one of the patient's clinical or biochemical parameters. The invention is also directed to a method of identifying an increased mortality risk factor for a patient undergoing periodic hemodialysis treatment. The method includes analyzing data of deceased patients that were previously undergoing periodic hemodialysis treatments by performing a longitudinal analysis backwards in time of changes in a clinical or biochemical parameter the patients, and identifying a significant change in the rate of decline or the rate of increase in a clinical or biochemical parameter before death of the patients. |
| US09883797B1 |
System and method for automatically tracking a contact lens in a wearer's eye
A system and method for automated determination of position and movement of a contact lens with respect to a subject wearer's eye based upon a complimentary pair of images, acquired in rapid succession, in which one image of the pair is acquired using light that allows viewing of the pupil and/or limbus through the lens and the other image is acquired using light that is absorbed by the lens to generate an opaque image with a defined edge relative to the surrounding sclera. The images of the pair are acquired in close enough temporal proximity to ensure that eye movement in the interval therebetween is insignificant and both images are in the same approximate reference frame. Thus, the location of the pupil and limbus in one image can be accurately compared with the location of the contact lens edge in the other image. |
| US09883796B2 |
Ophthalmologic system and method of operating the same
An ophthalmologic system comprising and eye tracker and an OCT system. A method of operating the ophthalmologic system comprises: providing data representing a placement of a first B-scan performed on an eye relative to the eye; performing a measurement on the eye using the eye tracker; determining a placement of the eye relative to the ophthalmologic system based on the measurement using the eye tracker; placing the eye relative to a reference placement of the OCT system based on the provided data and the determined placement; performing A-scans on the eye at at least three A-scan positions; determining a placement of a second B-scan relative to the OCT system based on at least one of the at least three A-scans and the provided data such that the second B-scan and the first B-scan have a substantially same placement relative to the eye; and generating a representation of the second B-scan. |
| US09883794B1 |
Method and apparatus for testing for color vision loss
A method and apparatus for administering eye tests to identify cone sensitivity loss associated with hereditary and acquired color vision loss which may be used for early detection, progress, treatment, and monitoring of eye conditions, traumatic brain injury, optic neuritis, systemic and neurological diseases including Glaucoma, Retinopathy, Age-Related Macular Degeneration, Multiple Sclerosis, Alzheimer's Disease, and Parkinson's Disease and retinal toxicity. Particularly, the method and apparatus disclosed uses a Cone Contrast Test (CCT) to test individuals for hereditary or acquired color vision loss associated with (a) early signs of potential disease/damage/toxicity in an effort to (i) provide opportunity for treatment, and (ii) prevent permanent eye damage, and (b) monitor progress and treatment of such disease/damage/toxicity. The system comprises a computer system including an input device and a display device, and the accuracy and repeatability of the testing is provided by repeated calibration using a colorimeter. |
| US09883791B2 |
Disposable sheath for an endotracheal intubation device
A sheath for an endotracheal intubation device includes an elongate flexible portion defining a closed conduit and an adjacent open channel defined by opposing lips for releasably retaining an endotracheal tube, and a rigid portion extending from a distal end of the flexible portion, the flexible portion including a gap in one of the lips adjacent the rigid portion to expose an edge of the rigid portion, the gap allowing the endotracheal tube to be pinched between the edge of the rigid portion and a lip of the flexible portion to enhance retention of the tube when an articulated arm disposed in the closed conduit is curved, and facilitate release of the tube when the arm is not curved. |
| US09883782B2 |
Liquid filtration vacuum
According to one embodiment, an upright liquid filtration vacuum cleaner includes a vacuum nozzle head and a housing moveably coupled to the vacuum nozzle head. The vacuum cleaner further includes a liquid tank that includes a wall defining an interior volume and a tank intake channel positioned in the interior volume. The interior volume is configured to hold a liquid. The tank intake channel is positioned to direct debris received from an intake passageway into the liquid tank so that the liquid in the interior volume of the liquid tank filters the debris into the liquid so that clean air is exhausted. The vacuum cleaner further includes a separator configured to generate an airflow. The vacuum cleaner is configured to seal the intake passageway when the vacuum cleaner is deactivated and further configured to unseal the intake passageway when the vacuum cleaner is activated. |
| US09883778B2 |
Mobile robot
A mobile robot including a body having a drive arrangement for driving the body on a surface, the body further including a bias for biasing a rear portion of the body in a direction away from the floor surface. The bias may include a spring-loaded swing arm located on a rear portion of the body and which is movable between stowed and deployed positions. |
| US09883775B1 |
Beard-grooming clean up sheets
The beard-grooming clean up sheets involves a sheet member with a domed recess thereon. The domed recess is adapted to be positioned over a faucet of a sink in order to divert hair trimmings associated with personal grooming away from the faucet. Moreover, the domed recess is an adjunct of the sheet member. The sheet member is generally planar, and is adapted to be draped over the sink. Both the domed recess and the sheet member are surrounded with a plurality of sheet armatures that span outwardly with respect to the domed recess and the sheet member. The plurality of sheet armatures are adapted to engage counter surfaces surrounding the faucet and the sink. Moreover, adhering members is provided on a bottom surface of two opposing ones of the plurality of sheet armatures. The adhering members is adapted to temporarily secure the sheet member in place. |
| US09883771B2 |
Grill accessory for providing food access and maintaining airflow control
The disclosed technology includes a grill accessory for use with a kamado-style grill to enable a user to control the flow of heat throughout the grill and maintain temperature of the cooking chamber. The grill accessory may enable a user to control the flow of heat throughout the grill, providing the user with greater customization of cooking options. The grill accessory may further enable a user to visually inspect a cooking food item while reducing the amount of heat loss from the grill. |
| US09883770B2 |
Vertical grill with external drip tray module
A vertical grill comprises a back chimney within the housing having an inlet and an outlet. The inlet is in the form of one or more first openings in the back frame member, and the outlet being a second opening which is higher than the inlet. A first air intake located in at least one of the grill's panels. A removable tray module comprises a slide positioned at an incline between the front and back sides, configured to direct fats and break away solids to the front side of the tray. At least one channel is covered by the slide and configured for air flow. An external receptacle is positioned at the front side of the tray, wherein the slide leads into the receptacle so that fats and break away solids may be channeled into the external receptacle after traveling downwards along the incline of the slide. |
| US09883767B2 |
Beverage cartridge
A beverage cartridge for use in a beverage dispensing system, comprising a housing, and located within the housing, a container for accommodating a beverage-related fluid substance and a pump; a drive port via which a driving torque may be delivered to the pump; and a fluid outlet port via which the fluid substance may be pumped from the cartridge; wherein the fluid outlet port and the drive port are located on the same side of the housing. |
| US09883766B2 |
Beverage dispenser systems and methods
A cartridge adaptor system may include a puncturing device; a nozzle adaptor including: a puncture port configured to receive the puncturing device; a nozzle coupling portion configured to releasably couple to a beverage dispenser nozzle; and a cartridge coupling portion configured to releasably couple to a cartridge containing a beverage ingredient; and a cartridge holster having a receiving portion for receiving a portion of the cartridge. The puncturing device may be configured to puncture the cartridge thereby releasing the beverage ingredient. |
| US09883764B2 |
Kettle cooker
The disclosed technology is a kettle supported by a base, with a burner mounted to the base and positioned below the bottom of the kettle. The kettle generally has a rounded bottom and straight sidewalls, although various curved portions of the kettle sidewalls are possible including a purely semispherical section. The kettle is provided with a U-shaped handle on each side which provides a gripping handle and also provides a means of rotating the kettle. The stand includes two grooves in a side portion, and the kettle can be tipped to one side and rotated to pour out the contents of the kettle, with the groove providing stability while the kettle is rotated to one side. The kettle rotates at a point which is not the center point of the kettle. |
| US09883763B1 |
Heating curtain rod with integrated speakers
A shower curtain and window curtain hanging structure provides constant stream of heated air as well as the ability to sound audio from an external source. The hanging structure includes a tubular body, an at least one heating fan assembly, an at least one rechargeable battery, an at least one waterproof speaker, and a wireless communication device. The tubular body supports various types of curtains. The rechargeable battery, the heating fan assembly, and the wireless communication device are all internally mounted within the tubular body. The waterproof speaker is integrated into an external surface of the tubular body in order to sound audio towards a user. The heating fan assembly includes an impeller, a heating element, and an electric motor. The impeller is powered by the electric motor in order to forces air to pass by the heating element and expelling heated air onto the user. |
| US09883762B1 |
Tree skate
The present invention is a tray apparatus providing mobility of a Christmas tree in a tree stand. The invention comprises a pan for placing the tree stand and a releasably attached handle. The improved mobility provided by the smooth, low-friction pan and removable handle of the present invention assists in decoration of the tree by allowing rotation for placing lights and ornaments, or other decorating tasks, as well as to present a favored side toward a desired area of the room in which it is placed. The tree may also be decorated in any convenient location and then moved laterally into the desired final position. In addition to the relatively frictionless movement provided by the pan, it also provides a basin to contain any water that spills from the stand, to catch needles, to hold presents, and to protect the floor or carpet. |
| US09883758B2 |
Drinking vessel
A drinking vessel for determining an amount of a liquid which is consumed and which includes a first portion, which has a base portion and a vertically, upwardly extending wall, and wherein the vertically upwardly extending wall defines an internal cavity, and the exterior-facing surface thereof defines a multiplicity of continuous, circumscribing, longitudinally spaced grooves; and a multiplicity of continuous, elastomeric members are individually received in the respective spaced grooves and which can be moved along the exterior-facing surface of the drinking vessel so as to permit a user to readily account for the amount of fluid they have consumed during a given time interval. |
| US09883757B2 |
Frame with integrated surface attachment for drywall and drywall-like surfaces
A frame and a device for mounting a plurality of frames in a grid. The frame has an axial first mounting member and a second mounting member, the first mounting member having a generally flat portion exposed to and generally flush with a perimeter surface of the frame. The alignment device has a cross-shaped body having a pair of horizontal members and a pair of vertical members intersecting at a common point, the horizontal and vertical members having interior surfaces defining four quadrants, the alignment device further comprising a level attached to the cross-shaped body and a magnet mounted in a recess in one of the horizontal members or vertical members. The alignment device used to position and mount the frame. |
| US09883755B2 |
Shelving system
A shelving system includes a plurality of horizontal support members, each horizontal support member having a length; a plurality of wall supports, each wall support including a first surface on which at least a portion of a horizontal support member rests; a plurality of brackets, each bracket attachable to the horizontal support members at different positions along the length of the horizontal support member; a plurality of vertical support members, each vertical support member coupled to at least one bracket; and a shelf attached to at least two of the plurality of vertical support members. |
| US09883754B1 |
Display for consumer articles
A display for creating at least two differently configured articles, each of which comprises at least a first component and at least a second component. The display includes a first support on which at least two of the first components are arranged; a second support, spaced apart from the first support, on which at least one second component is arranged, and wherein the first support and the second support are rotatable with respect to each other; wherein the two components on the first support are each separately alignable, but not simultaneously, with the component on the second support thereby separately creating a visual impression of at least two substantially completed articles. A method of creating at least two differently configured articles, using the aforementioned display, is also provided. |
| US09883750B2 |
Frame height adjusting mechanism and frame therewith
A frame height adjusting mechanism is adapted for a frame including an inner pipe and an outer pipe sheathing on the inner pipe. A fixing hole is formed on one of the inner pipe and the outer pipe. A plurality of positioning holes is formed on the other one of the inner pipe and the outer pipe. The frame height adjusting mechanism includes a driving member which is slidably disposed on the inner pipe or the outer pipe where the fixing hole is formed and includes at least one first inclined surface, and at least one engaging member which is slidably disposed on the driving member and passing through the fixing hole to insert into one of the plurality of positioning holes. The at least one first inclined surface pushes the at least one engaging member to disengage from the corresponded positioning hole when the driving member slides upwardly. |
| US09883749B2 |
Convertible high chair
Various embodiments of the present invention are directed to a convertible children's high chair. According to various embodiments, the convertible high chair generally comprises a first child seat supported above a floor by a high chair frame, and a second child seat configured for being removably coupled to first child seat. The second child seat is configured such that, when detached from the high chair's first child seat, it can be used apart from the high chair as a booster seat (e.g., secured to the seating surface of a standard chair or another support surface). In certain embodiments, the second child seat includes a base surface configured to stably support the second child seat on a separate support surface (e.g., without the need to be attached to or mounted on a separate base or support member). |
| US09883748B2 |
Training device for a seating device and method of using the same
A seating device includes a training device connected to a component of the base of the seating device. The training device is configured to tilt the seating device to help a user learn how to use the seating device to help the user avoid losing the user's balance while sitting or leaning on the seat of the seating device when the user initially starts to use the seating device. The training device can be releasable from the base of the seating device after the user has learned how to balance on the seating device. The training device can also be reattachable to the seating device to facilitate the training of other users. |
| US09883743B2 |
Firearm lock shroud
A firearm lock shroud for a firearm lock comprises first and second side members. The first side member is positioned adjacent the firearm lock. The second side member is positioned adjacent the firearm lock and spaced apart from the first side member. The first and second side members define a firearm receiving space therebetween for receiving a firearm. The first and second side members extend over an area to cover at least a trigger area of a firearm received in the firearm receiving space and locked by the firearm lock to prevent unauthorized access to the trigger area. The side members can optionally extend to cover a magazine area and/or a take-down pin area of the firearm. |
| US09883738B2 |
Bottle cap stadium table
A bottle cap stadium/arena table related to the field of indoor/outdoor furniture. More specifically, a table that mimics a stadium/arena in which sports fans can customize using their own bottle caps. The inventive device includes a table frame with perforated plates that hold decorative bottle caps around the central sporting area that mimics people sitting in the stands; including miniature accessories to depict a particular sporting event (goals, flags). The table, which mimics a miniature stadium/arena, includes a glass tabletop that acts as the table's surface. The table is user customizable to a specific sporting team. |
| US09883734B2 |
Holding device for a mobile multimedia terminal
A holding device for a mobile digital multimedia terminal having a holding arm and a fastening device at a first end of the holding arm for fastening to a headgear so that the holding arm extends from the headgear towards a front in the direction of view of a user. A holder for the multimedia terminal is arranged at the second end of the holding arm that is adjustable in reference to the holding arm such that the graphic display is essentially locatable in the middle of a view field. A clamping element with a clamping structure and a counterpart to the clamping element are provided in proximity to the first end to connect the clamping element in a detachable fashion to the holding arm and to fix the holding device in a detachable fashion with the first end of the holding arm in the proximity of the clamping structure. |
| US09883730B2 |
Wrist wearable terminal
Provided is a wrist wearable terminal including: a body portion including a function module; a coupling portion fastening the body portion on a wrist; and at least one strap portion linking the body portion and the coupling portion and including at least one function module that is coupled to the function module of the body portion via a signal line to convert or activate a use of at least one function of the wrist wearable terminal depending on a state of wearing of the wrist wearable terminal. |
| US09883729B2 |
Hydra ring
A lightweight hydration backpack is disclosed that can go under or over clothing and is hands free with tubes that work in the same way canvas straps work on a backpack making it easy to slip on or off. The tubes, which also double as left and right shoulder straps, deliver the liquid to the user along with supporting the weight of the liquid in the collapsible bottles on the back of the pack. The tubes can be easily released from the connectors by hand, allowing for easy cleaning and also allowing the user to cut the released tubes to fit his or her own torso size. |
| US09883727B2 |
Pattern assembly
A pattern assembly helps control the removal of hair by joining a template of a predetermined hair pattern directly on the body, such as the face, in conjunction with the application of a depilatory composition. At least one middle template, at least one right template, and at least one left template join correlating middle, right, and left regions of a body, such that the depilatory composition may be applied on the body, generally around the edges, and proximal to the templates. The templates includes a mount surface that engages the body, and an outer surface that is visible. The edges of the templates are tapered so as to inhibit seeping of the depilatory under the template. A handle portion enables holding and manipulation of the templates. An alignment portion enables measured positioning of the templates. The templates are flexible to conform to the various angles of the face. |
| US09883726B2 |
Hair dryer with improved outlet unit
A hair dryer includes a main body and an outlet unit. The outlet unit is provided therein with an air-guiding member, which can convert a linearly ongoing air current into a rotationally ongoing air current. Furthermore, the outlet define a plurality of air holes, through which outside air can be drawn into the outlet unit to mix with the air current flowing out of the exit of the main body, to increase air speed, uniformity and penetration and to reduce noise. |
| US09883723B2 |
Method for providing nanocrystalline diamond coatings on gemstones and other substrates
A method to apply nano-crystalline diamond onto a selected substrate, including preparing Nanodiamond slurry of Nanodiamond particles dispersed in a medium. The medium may include a liquid or a sol-gel. The selected substrate is immersed in the Nanodiamond slurry for a predetermined period of time. Then the substrate is removed from the slurry. The substrate is then dried with a flow of inert gas. The substrate is left coated with a coating of the nanodiamond particles that are highly adherently held by van der Waals forces. |
| US09883722B2 |
Wristwatch comprising a clasp connected to the case
A wristwatch, comprising: a watch case (2); a clasp (3), said clasp comprising a frame (4) that can clip over the top of the watch case (2) in a closed position, and that can be unfastened from the watch case (2) in an open position; a bracelet (12), said bracelet comprising a single strand, said strand having a first end (120) and a second end (121); said first end being connected to said watch case (2) and said second end being connected to the clasp (3); a locking member (5) connected to the watch case, the locking member being able to be pivoted between a position that allows it to be inserted into the opening (40) of the frame (4) when the clasp (3) is being closed or opened, and a locking position that allows the opening or closure of the clasp (3) to be blocked. |
| US09883721B2 |
Palm bracelet
Embodiments of the present disclosure provide a multi-membered bracelet. The palm bracelet includes three members connected by connecting chains. In some embodiments, one of the three members is configured to rest within the space between the thumb and index finger. In some embodiments, one of the connecting chains is configured to rest within the space between the thumb and index finger. |
| US09883720B1 |
Zipper capable of generating a distinctive sound
A zipper without electrical components that generates a distinctive sound when the zipper is opened or closed is disclosed herein. The zipper comprises a slider, a first and a second track. The slider comprises a plurality of tone bars and a plurality of audio openings. The first track comprises a plurality of zipper teeth. The second track comprises a plurality of zipper teeth. Each zipper tooth of the plurality of zipper teeth of the first track and the second track comprises at least one raised portion. The slider is configured to generate a musical sound when the slider is slid over the first track and the second track. |
| US09883715B2 |
Article of footwear with outsole web and midsole protrusions
An article of footwear is disclosed that includes an upper, an outsole, and a midsole. The upper is configured to receive a foot, and the outsole is secured to the upper. The outsole defines a plurality of apertures extending entirely through the outsole. In addition, the outsole has a ground-engaging surface positioned at a first elevation. The midsole is positionable such that a lower surface of the midsole extends into the apertures of the outsole and is exposed by the apertures. |
| US09883705B1 |
Baby garment with multiple interchangeable themed knee pads
The baby garment with multiple interchangeable themed knee pads is adapted for use with infants. Specifically, the baby garment with multiple interchangeable themed knee pads is a pair of pants intended for infants wherein non-skid knee pads are attached to the pants such that the knee pads will rest between the knee of the infant and the surface upon which the infant is crawling. The knee pads of the baby garment with multiple interchangeable themed knee pads are removable and replaceable. A plurality of knee pads are provided for esthetics purposes. The baby garment with multiple interchangeable themed knee pads comprises pants, a plurality of hook and loop fasteners, and a plurality of knee pads. |
| US09883701B2 |
Air bra
A brassiere for breast enhancement and breast safety in women is disclosed. The brassiere has two cups which are at least partially comprised of stretchable material and house an air-tight chamber inserted into either one or both of the cups, a pump or tube for inflating and deflating air in the chambers using an air valve and a press button. The brassiere of the present invention uses the air chamber(s) to protect the chest area of a woman from impact and is used for enlarging and beautifying the breasts of women. |
| US09883700B2 |
Aerosol-generating device and system
An electrically heated aerosol-generating system is provided, including a primary device and a secondary, aerosol-generating, device having a cavity at a proximal end configured to removably receive an aerosol-generating substrate. The primary device includes a housing; a power supply; a cavity in the housing configured to receive the secondary device; a plurality of electrical contacts within the cavity, each contact being configured to contact a corresponding contact of the secondary device when the secondary device is in the cavity, at least one of the contacts being connected to the power supply; and a lid configured to cover an opening of the cavity, and being moveable between a first closed position, and a second open position. The lid includes a protrusion configured to prevent movement from the second position to the first position if the secondary device is inserted incorrectly. |
| US09883698B2 |
Replaceable vaporizer assembly and electronic cigarette having the same
The present disclosure relates to a replaceable vaporizer assembly and an electronic cigarette having the replaceable vaporizer assembly. In certain embodiments, the electronic cigarette may include an electronic cigarette body, and a replaceable vaporizer assembly. The electronic cigarette body may include a mouthpiece installed in a mouthpiece base, a connector base, a mounting base, an E-liquid storage tank, and a connector. The mounting base and the connector base are threadedly connected through a first internal thread of the mounting base and an external thread of the connector base to form an air chamber inside of the mounting base and the connector base. When in operation, outside air enters the air chamber through the multiple air intake openings and is vaporized by the replaceable vaporizer assembly, goes up through multiple air gaps between the mounting base and the connector base, and exits the electronic cigarette body through the mouthpiece. |
| US09883688B1 |
Method for making citrus juice powder
Disclosed are improved citrus fruit juice powders and methods of providing the improved citrus fruit juice powders. The citrus fruit juice powders are neutralized and are free of fillers, such as maltodextrin. Also disclosed are meat marinades that include the improved citrus fruit juice powder. |
| US09883687B2 |
Dehydrated vegetable food product and methods of making the same
A vegetable food product and a method of making a dehydrated vegetable food product are provided. A quantity of vegetables is cut to a predetermined size. The quantity of cut vegetables is cooked. The quantity of cut vegetables has surface moisture removed. A flavoring material is imparted into the quantity of vegetables. The quantity of cut vegetables is substantially dehydrated, wherein each of the cut vegetables has a jerky-like texture, whereby shearing through the jerky-like texture requires a force of at least 30 N until a 95% strain is achieved utilizing a TA-HD Plus Texture Analyzer Device. The quantity of vegetable may include a quantity of potatoes. |
| US09883686B2 |
Glazing agent for pastry products and methods of manufacturing a glazing agent for pastry
Manufacturing a glazing agent bread or pastry products maintaining intrinsic tastes and flavors without destroying unique layered shape or collapsing the products. First prepare solution A by mixing 3 to 4 parts weight refined sugar and 0.5 to 1.5 parts weight amidated pectin, add 27 to 28 parts weight purified water, and dissolve at 80 to 85° C. for 20 to 25 minutes, second prepare solution B by mixing 0.2 to 0.3 parts by weight citric acid, 46 to 48 parts by weight starch syrup and 0.02 to 0.05 parts by weight black rice flavoring, adding 20 to 21 parts by weight purified water, heating at 60 to 65° C. for 10 to 15 minutes to dissolve, and third gelling the solution A and solution B by heating at 90 to 95° C. for 20 to 25 minutes to gel, and cooling the resulting mixture to room temperature. |
| US09883682B2 |
Method and apparatus for pasteurizing shell eggs using radio frequency heating
Radio frequency (RF) energy is used to quickly heat the yolk portion of a shell egg. An anode and corresponding cathode are applied to each individual egg. As the egg is selectively and systematically rotated, RF energy and a stream of cooling fluid (preferably water) are simultaneously applied to the egg. This initiates pasteurization of the egg yolk while maintaining a low temperature in the heat-sensitive albumen (egg white) thus preventing denaturation of the albumen. Immediately after the RF yolk heating process, the egg is placed in a hot water bath designed to rapidly pasteurize the albumen as well as to minimize heat loss from the yolk and pasteurize any portion of the yolk that is not already pasteurized through the RF yolk heating process. |
| US09883681B2 |
Wash away fillet tool
The wash away fillet tool is a new cutting board utensil designed primarily to be used to fillet fish; although, it could be used for other similar jobs. The design is a straightforward improvement of the cutting board which makes the job of filleting fish safer, cleaner, and faster. A water chamber attached to a cutting board is the key part. The water chamber permits water to flow across the working surface of the fillet tool. The flow of water washes undesirable waste material off of the fillet tool keeping the hands and knife free of fish slime. |
| US09883679B2 |
Biscuit dough
The present disclosure relates to a dough for producing a biscuit having a slowly-digestible-starch-over-total-available-starch ratio of at least 31%, the biscuit comprising at least 29 wt % cereal flour, 5 to 22 wt % fat and at most 30 wt % sugar relative to the total weight of the biscuit, the dough comprising: cereal flour, fat, sugar and added water; and wherein the added water is in an amount of at most 8 wt % relative to the weight of dough. |
| US09883676B2 |
Paenibacillus strain, antifungal compounds, and methods for their use
The present invention relates to a composition comprising a biologically pure culture of a fungicidal Paenibacillus sp. strain comprising a variant fusaricidin synthetase lacking a functional adenylation domain in the third module. The present invention also provides a composition comprising a biologically pure culture of a fungicidal Paenibacillus sp. strain or a cell-free extract thereof comprising at least one Paeniserine and at least one Paeniprolixin. Also provided are isolated compounds and methods of treating a plant to control a plant disease with the disclosed compositions and compounds. |
| US09883675B2 |
Method for controlling pests
The present invention provides a method for controlling pests which comprises applying a compound of formula (1): wherein each of symbols are the same as defined in the Description, or N-oxide thereof to plant seeds, which has an excellent controlling efficacy on pests. |
| US09883668B2 |
Self propelled agricultural application machine
A self-propelled agricultural application machine includes a chassis which carries a storage tank for the material to be applied. The chassis has a central longitudinal beam from which at least a pair of wheels is suspended. A transversely-extending boom assembly is suspended from the longitudinal beam. An engine is located to one side of the longitudinal beam and has an output drive shaft connected through the longitudinal beam to hydraulic pumps. The narrow chassis allows steerable wheels to be positioned at tolerable track widths while permitting a large steering angle and thus small turning radii. |
| US09883661B2 |
Multi-path aquarium filtration apparatus
A multi-path aquarium filtration system having multiple chambers adapted to receive different types of treatment systems, and having a bypass gate assembly whereby the flow volume between certain chambers is adjustable. |
| US09883659B2 |
Feeding station for poultry chicks
A chick feeding station having an elongate trough for holding poultry feed, a conveyor which is placed in the trough and moves feed in the longitudinal direction of the trough, and deflectors and supports that provide chick safety. The conveyor is a chain conveyor with flights. The deflectors are mounted on the chick feeding station such that they extend from just above the conveyor flights and obliquely upward in the direction of travel of the conveyor, to move a chick to an upper level of the trough. A support for each deflector is also provided in the trough, the supports extending above the flights in the longitudinal direction of the trough, all the way to and through the deflectors. |
| US09883657B2 |
Conductive polymer multi-ridge electrode animal collar
A collar for conditioning behavior in an animal and system and method for same are disclosed. The collar includes a main body configured to generate electric stimuli. A pair of conductive polymer multi-ridge electrodes extends outward in a concave configuration from base portion of main body at first end and second end of base portion such that electrodes and base portion form a unitary component. The pair of electrodes is configured to have inner and outer indentations integrally formed with base portion such that inner indentations are suitable for receiving smaller animals and outer indentations are suitable for receiving larger animals. A housing receives main body and is integrally formed with a pair of elongated planar members extending orthogonally from band portion of collar at first end and second end of housing such that collar is positioned around animal neck while inserted to main body for support. |
| US09883654B2 |
Arrangement of milking box stalls
A system includes a first milking box stall of a size sufficient to accommodate a first dairy livestock and a second milking box stall of a size sufficient to accommodate a second dairy livestock. The first and second milking box stalls face opposite directions. An equipment portion is located between the first milking box stall and the second milking box stall. A robotic attacher is housed in the equipment portion and configured to service both stalls at different times. The robotic attacher comprises a gripping portion having a spray nozzle. The gripping portion is operable to rotate around a longitudinal axis such that during a milking operation the spray nozzle is positioned on the bottom of the gripping portion, and after the milking operation the spray nozzle is positioned on the top of the gripping portion. |
| US09883650B2 |
Lettuce named DESERT EAGLE
Novel lettuce, such as lettuce designated DESERT EAGLE is disclosed. In some embodiments, the invention relates to the seeds of lettuce DESERT EAGLE, to the plants and plant parts of lettuce DESERT EAGLE, and to methods for producing a lettuce plant by crossing the lettuce DESERT EAGLE with itself or another lettuce plant. The invention further relates to methods for producing a lettuce plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other lettuce plants derived from the lettuce DESERT EAGLE. |
| US09883646B1 |
Maize inbred PH2SRD
A novel maize variety designated PH2SRD and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety PH2SRD with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH2SRD through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety PH2SRD or a locus conversion of PH2SRD with another maize variety. |
| US09883645B1 |
Maize hybrid X13H924
A novel maize variety designated X13H924 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X13H924 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X13H924 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X13H924, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X13H924. This invention further relates to methods for producing maize varieties derived from maize variety X13H924. |
| US09883644B2 |
Hybrid sweet corn plant HMX4372BS
A novel sweet corn hybrid plant, designated HMX4372BS is disclosed. The invention relates to the seeds of sweet corn hybrid HMX4372BS, to the plants and plant parts of sweet corn hybrid HMX4372BS, and to methods for producing a sweet corn plant by crossing the sweet corn hybrid HMX4372BS with itself or another sweet corn plant. The invention further relates to methods for producing a sweet corn plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other sweet corn plants derived from the sweet corn hybrid plant HMX4372BS. |
| US09883642B2 |
Vertical assembly for growing plants
A device for growing plants is provided. The device has a panel assembly on which a one or a plurality of nutrient flow channels is supported to provide nutrient flow passages from an inlet at an upper region to an outlet at a lower region of the support panel. A plurality of grow pockets is supported on an opposite side face of the support panel, the grow pockets in alignment with the nutrient flow channels. Each grow pocket has a plant access opening. A fluid aperture in the support panel is disposed at a lower region of each grow pocket for fluid communication between an interior of the grow pocket and the aligned nutrient flow passage. |
| US09883631B2 |
Crop processing apparatus in a combine harvester
A combine harvester comprises a threshing unit arranged to receive and thresh a crop stream. Separating apparatus are located downstream and rearward of the threshing unit and are arranged to receive the threshed crop stream and convey such a rearward direction. The front of a return pan, disposed below the separating apparatus, overlaps the rear of a stratification pan, disposed below the threshing unit. The stratification pan is driven in an oscillating manner to convey a primary grain/chaff stream rearwardly to a rear edge from where the primary grain/chaff stream falls under gravity into a cleaning unit. The return pan is driven in an oscillating manner to convey a secondary grain/chaff stream forwardly to a front edge from where the secondary grain/chaff stream falls under gravity to combine with the primary grain/chaff stream on the stratification pan. The cleaning unit comprises a fan for generating a cleaning airstream which is directed through the falling grain/chaff stream to encourage the lighter material away from the grain. A plurality of crop flow disrupting elements in the form of fins or tines are secured to the underside of the return pan above the stratification pan to disrupt the grain/chaff stream and enhance stratification thereof. |
| US09883629B2 |
Ground treatment device
An apparatus for performing a ground treatment, such as aeration or dethatching, is provided. The apparatus includes a base frame component to which a pair of angled side frame components are pivotally mounted. Each angled side frame can include first and second ends that are oriented to form a central angle. A first end of an angled side frame can be pivotally attached to a wheel and/or the base frame component, while the second end can include a mechanism for mounting a ground treatment component. |
| US09883628B2 |
Anti-wind/anti-wrapping assembly for trimmers
An anti-winding assembly reduces or prevents debris from winding on a trimmer and/or makes them easier to remove. The trimmer includes a trimmer head mounted to a rotatable arbor and supporting one or more cutting lines. The anti-winding assembly includes a bearing positionable between the trimmer head and an adjacent trimmer component. The bearing includes a freely rotating outer race. A shield positioned radially outward of the bearing adjacent the outer race shields gaps between the bearing and the trimmer head and between the bearing and the adjacent trimmer component. The anti-winding assembly prevents trimmed debris from being wound up near the trimmer head. |
| US09883627B2 |
Device for picking up harvested root crop
A pick-up arrangement for picking up harvested crop, comprises a pick-up device which has a pick-up device frame defining a pick-up opening located on a pick-up side of the pick-up device and a pick-up member, located on the pick-up side and, adapted to pick-up harvested crop and defining a pick-up width, and a guiding device adapted to guide harvested crop located outside the pick-up width into the pick-up opening. The pick-up device defines a pick-up direction. The guiding device comprises a guiding device frame and a first guiding member extending outside the pick-up width, being rotatably mounted with respect to the guiding device frame, and being adapted to transport harvested crops located outside the pick-up width into the pick-up opening. |
| US09883626B2 |
Controlling an agricultural vehicle based on sensed inputs
A variable is sensed that is indicative of a performance of a machine. A rate of change of the sensed variable is determined, and a control signal is generated for controlling an agricultural vehicle, based upon the rate of change in the value of the sensed variable. |
| US09883625B2 |
Crop input variety selection systems
Systems, methods and apparatus are disclosed for selecting an agricultural input. First and second seed meters selectively meter seed from first and second sources, respectively, into a common planting trench. In some embodiments the seed meters are selectively operated by electric motors controlled with reference to a seed type prescription. In some embodiments the first and second seed meters deposit seeds along a common plane. |