Document Document Title
US09822229B2 Low emissivity film
The present invention concerns a functional film material comprising a substrate layer and a coating layer, the coating layer comprising a block copolymeric binder and a particulate metal pigment therein, the ratio of pigment to binder in the coating layer being selected with reference to the coat weight to provide the functional film material with an emissivity of less than 0.5, and the substrate and coating layer being selected to provide the film with a VWTR (ambient) in excess 400 gm−2 d−1 bar−1.
US09822227B2 High Tg epoxy formulation with good thermal properties
Varnish compositions and prepregs and laminates made therefrom wherein the varnish compositions include at least one first epoxy resin and at least one second epoxy resin that includes a bisphenol-A novolac epoxy resin and a harder wherein the at least one first epoxy resin and the at least one second bisphenol-A novolac epoxy resin are present in the varnish at a weight ratio ranging from about 1:1 to about 1:3.
US09822223B2 Method of preparing a composition based on hyaluronic acid
The invention relates to a method of preparing a composition, the composition comprising a crosslinked first polymer, optionally a second polymer, which may be crosslinked or non-crosslinked, and water, wherein the first and the second polymer are selected from a polysaccharide, comprising at least steps (i) to (iv): (i) crosslinking a mixture comprising the first polymer and water; (ii) subsequent to the crosslinking in step (i), terminating the crosslinking; (iii) optionally blending the product obtained in step (ii) with the second polymer; (iv) subjecting the product obtained in step (iii) to dialysis.
US09822222B2 Biodegradable and biocompatible shape memory polymers
This invention relates to shape memory block copolymers comprising: at least one switching segment having a Ttrans from 10 to 70° C.; and at least one soft segment, wherein at least one of the switching segments in linked to at least one of the soft segments by at least one linkage, and wherein the copolymer transforms from a first shape to a second shape by application of a first stimulus and the copolymer transforms back to the first shape from the second shape by application of a second stimulus. The shape memory block copolymers may be biocompatible and biodegradable.
US09822221B2 Cross-linked composition and method of forming the same
A cross-linked composition comprises the reaction product of a first reactant having at least one hydroxyl or amine (functional) group, a second reactant having at least one hydroxyl or amine (functional) group, and a siloxane having at least two terminal anhydride groups reactive with the functional groups of the first and second reactants. The first reactant is selected from the group of first siloxanes having at least one hydroxyl or amine group, a first organic alcohol having at least one hydroxyl group, a first organic amine having at least one amine group, or combinations thereof. The second reactant is selected from the group of second siloxanes having at least one hydroxyl or amine group, a second organic alcohol having at least one hydroxyl group, a second organic amine having at least one amine group, or combinations thereof. If utilized, the first siloxanes and/or second siloxanes are different from the siloxane.
US09822217B2 Robust resin for solvent-free emulsification
A branched polyester suitable for use in solvent-free emulsification, the branched polyester having a first original weight average molecular weight before undergoing solvent-free emulsification and a second weight average molecular weight after undergoing solvent-free emulsification, wherein the branched polyester has a structure that limits degradation of the polyester during solvent-free emulsification to less than about 20 percent of the first original weight average molecular weight, wherein the branched polyester comprises a compound of the formula described.
US09822215B2 Etheramines with enhanced thermal stability and their use as curatives or intermediates for polymer synthesis
Implementations described herein relate to an etheramine mixture containing a cyclobutane based amine and its method of production by alkoxylating an initiator with an alkylene oxide to produce a precursor polyol and reductively aminating the precursor polyol to form the ehteramine mixture. The etheramine mixture may be used in a variety of applications including as a curing agent for an epoxy resin or as a reactant in the production of polyurea materials.
US09822214B2 Curable compositions
Embodiments include curable compositions including an epoxy resin and a hardener component including a polymer having first constitutional unit, a second constitutional unit, and a third constitutional unit, where the epoxy group to the second constitutional unit has a molar ratio in a range of 0.5:1 to 5:1. Embodiments include prepregs that include a reinforcement component and the curable composition and an electrical laminate formed with the curable composition.
US09822209B2 Method for decomposing polymer material, method for producing recycled resin, and method for recovering inorganic filler
The present invention is a method for decomposing a polymer material by chemically decomposing a polymer material containing a first monomer and a second monomer in a mixture of the polymer material with the first monomer or a derivative of the first monomer to produce a chemical raw material. A relationship between a proportion of number of molecules of the second monomer to number of molecules of the first monomer in a reaction system for decomposing the polymer material and the molecular weight of the chemical raw material produced in the reaction system is acquired in advance (S101). Subsequently, an addition mount of the derivative of the first monomer to be added to the polymer material is determined based on the above relationship (S102). The first monomer in the addition amount determined is then mixed with the polymer material (S103).
US09822207B2 Silicon-containing highly branched polymer and curable composition containing the same
There is provided a composition for forming a hard coat layer which has high slippage and is excellent in water/oil repellency and also has antifouling properties such as fingerprint resistance and dirt wiping-off properties, and which is curable through ultraviolet irradiation in a nitrogen atmosphere or an air atmosphere that is generally used. A silicon-containing highly branched polymer obtained by polymerization of a monomer A having two or more radically polymerizable double bonds in a molecule and a monomer B having a polysiloxane chain and at least one radically polymerizable double bond in a molecule in the presence of a polymerization initiator D in an amount of 5 to 200% by mole relative to the number of moles of the monomer A; a curable composition including the highly branched polymer; a cured film obtained from the composition; and a hard coat film obtained by use of the composition.
US09822206B2 Copolymers for near-infrared radiation-sensitive coating compositions for positive-working thermal lithographic printing plates
There is provided a copolymer having the general structure below, wherein a, b, and d are molar ratios varying between about 0.01 and about 0.90 and c is a molar ratio varying between about 0.01 and about 0.90; A1 represents monomer units comprising a cyano-containing pendant group in which the cyano is not directly attached to the backbone of the copolymer; A2 represents monomer units comprising two or more hydrogen bonding sites; A3 represents monomer units that increase solubility in organic solvents; and A4 represents monomer units that increase solubility in aqueous alkaline solutions. There is also provided a near-infrared radiation-sensitive coating composition comprising this copolymer as well as a positive-working thermal lithographic printing plate comprising a near-infrared radiation-sensitive coating comprising this copolymer, a method of producing such a printing plate, and finally a method of printing using such a printing plate. Formula (I).
US09822205B2 Deoxybenzoin-derived anti-flammable polymers
The invention provides novel flame-retardant polymers and materials, their synthesis and use. More particularly, the flame-retardant polymers are deoxybenzoin-derived polymers.
US09822202B2 Polymer/copper combination for targeted cancer therapy
Polymer/copper combination that can selectively target and kill cancer cells are described. Materials can include the reaction product of a biocompatible hydrophilic polymer and pyridine-2-thiol containing monomer. The copolymer reaction product can include pyridine-2-thiol side groups pendant to the backbone via a disulfide linkage. The hydrophilic component can form the polymer backbone and/or can form hydrophilic pendant groups off of the backbone. Copper ions can be associated with the copolymer.
US09822201B2 Reflective particle, particle dispersion liquid, display medium, and display device
The invention relates to reflective particles containing a resin containing a structural unit derived from a compound represented by the following Formula (1), wherein in the formula (1), R represents a polymerizable group except a vinyl group, Ar represents an aromatic group, and W represents a single bond or a divalent linking group. R—W—Ar  Formula (1)
US09822197B2 Method for producing superabsorbers based on renewable raw materials
A process for producing water-absorbing polymer particles, comprising the steps of thermal cracking of bionaphtha in the presence of steam, removing propene and at least some of the propane, gas phase oxidation to give acrylic acid and polymerization to give water-absorbing polymer particles.
US09822194B2 Universally dispersible particles containing hydrogen bonds
The present invention is directed to an entity comprising a particle attached to at least one polymer M through one or several supramolecular interactions -A-B- constituted by 2 to 8 hydrogen bonds X-H-Y, wherein A and B are functional groups respectively grafted to P and M thus forming the particle-containing entity P-(A-B-M)x with x being greater than or equal to 1, functional group(s) B being positioned at one end of the polymeric chain of polymer M, X and Y are heteroatoms present in A and B functional groups, H is hydrogen, and M has a degree of polymerization comprised between 5 and 1000, preferably ranging from 5 to 500. The invention is also directed to a method for preparing this particle-containing entity P-(A-B-M)x, a method for sequentially forming and breaking the supramolecular interactions -A-B- in said particle-containing entity P-(A-B-M)x and dispersions comprising the same.
US09822190B2 Compositions and method for anti-sickling of red blood cells in sickle cell disease
A nano-composition that includes nanoparticles, a method of forming the nano-composition, and a method of using the composition. The nanoparticles include a polycationic polymer ionically bonded to one or more polyanionic Glycosaminoglycans (GAGs), wherein the polycationic polymer is chitosan, methylated chitosan, poly L-Lysine, or poly L-Arginine.
US09822189B2 Bonding tissues and cross-linking proteins with naphthalimide compounds
Naphthalimide compounds are used in tissue bonding and protein cross-linking applications. When activated by an activating agent, such as light in the 400-500 nm absorption range, the naphthalimide compounds form chemically-reactive species that cross-link proteins, bond connective tissues together, and bond tissues and other biomaterials together. A naphthalimide-labeled biomolecule, such as a naphthalimide-labeled chitosan, is also capable of bonding tissues without subsequent direct illumination of the contacted tissue area. The naphthalimide compounds may be used in tissue or arterial repair, stabilization of an expanded arterial wall after angioplasty, tethering pharmaceutical agents to tissue surfaces to provide local drug delivery, and for chemically bonding skin care products, sunscreens, and cosmetics to the skin.
US09822187B2 Method for processing cellulose-containing biomass
Described are a method for processing cellulose-containing biomass and the use of methanesulfonic acid for processing cellulose-containing biomass, especially for the pretreatment of cellulose-containing biomass prior to saccharification.
US09822186B2 Bispecific antibodies that bind to CD38 and CD3
The invention provides novel heterodimeric proteins including heterodimeric antibodies.
US09822184B2 DCLK1 short form specific binding agents
Certain embodiments are directed to composition and methods related to DCLK1-S specific binding agents.
US09822183B2 CA6 antigen-specific cytotoxic conjugate and methods of using the same
Cytotoxic conjugates comprising a cell binding agent and a cytotoxic agent, therapeutic compositions comprising the conjugate, methods for using the conjugates in the inhibition of cell growth and the treatment of disease, and a kit comprising the cytotoxic conjugate are disclosed are all embodiments of the invention. In particular, the cell binding agent is a monoclonal antibody, and epitope-binding fragments thereof, that recognizes and binds the CA6 glycotope. The present invention is also directed to humanized or resurfaced versions of DS6, an anti-CA6 murine monoclonal antibody, and epitope-binding fragments thereof.
US09822182B2 Anti-EPCAM antibodies and methods of use
The present disclosure is related to compositions of antibodies and immunoconjugates that potentially lack T-cell epitopes and elicit reduced immune response. The antibody may be an antibody fragment, such as Fab, Fab′, F(ab′)2, scFv, dsFv, ds-scFv, dimers, minibodies, diabodies, bispecific antibody fragments, multimers, and any combination thereof. In a further embodiment, the antibody may bind to an antigen epithelial cell adhesion molecule (EpCAM). In another embodiment, an immunoconjugate may comprise an antibody attached to an effector molecule, wherein the effector molecule may be a radioisotope, an antineoplastic agent, an immunomodulator, a biological response modifier, lectin, a toxin, a chromophore, a fluorophore, a chemiluminescent compound, an enzyme, a metal ion, and any combination thereof.
US09822181B2 Bi-specific monovalent diabodies that are capable of binding CD123 and CD3, and uses thereof
The present invention is directed to sequence-optimized CD 123×CD3 bi-specific monovalent diabodies that are capable of simultaneous binding to CD 123 and CD3, and to the uses of such diabodies in the treatment of hematologic malignancies.
US09822178B2 Human PAC1 antibodies
Antibodies and antigen-binding fragments thereof that bind to human PAC1 are provided. Nucleic acids encoding the antibodies and antigen-binding fragments thereof, vectors, and cells encoding the same are also provided. The antibodies and antigen-binding fragments thereof can inhibit binding of PAC1 to PACAP, and are useful in a number of PAC1 related disorders, including the treatment and/or prevention of headache disorders, including migraine.
US09822177B2 Method of reducing pruritus using IL-31 monoclonal antibodies
The present invention relates to methods of treating pruritic diseases, including but not limited to Contact dermatitis, Atopic Dermatitis, Drug induced delayed type cutaneous allergic reactions, Toxic epidermal necrolysis, Cutaneous T cell Lymphoma, Bullous pemphigoid, Alopecia wereata, Vitiligo, Acne Rosacea, Prurigo nodularis, Scleroderma, Herpes simplex virus, or combination thereof by administering IL-31 monoclonal antibodies. The invention provides the hybridomas that generate the monoclonal antibodies and the amino acid sequences of the variable regions of the monoclonal antibodies and chimeric antibodies comprising the amino acid sequences of the light and heavy chain variable regions.
US09822176B2 IL-3 antibodies and their use in diagnosis and treatment of diseases or malfunctions associated with elevated levels of IL-3
Novel anti-interleukin 3 (IL-3) antibodies or fragments or constructs thereof according to the present invention specifically bind to an epitope contained within the N-terminal 20 amino acids of the amino acid sequence of human IL-3 according to SEQ ID No. 1, and preferably to a sequence motif SWVN (SEQ ID NO: 2). The antibodies can be used in diagnostic methods for the determination of IL-3 levels in body fluids, preferably in corresponding ELISA assays, but also in pharmaceutical compositions for the treatment or prevention of diseases which are associated with elevated levels of IL-3 in a patient, especially rheumatoid arthritis.
US09822170B2 Co-use of a clusterin inhibitor with an EGFR inhibitor to treat cancer
Epidermal growth factor receptor (EGFR) expression and phosphorylation is increased in cancer cells treated with anti-clusterin antibodies. Such treatment is also accompanied with the reappearance of an epithelial phenotype of the cancer cell, as determined by an increased E-cadherin expression at the surface of cancer cells. Clusterin inhibitors may thus induce reversal of the epithelial to mesenchymal phenotype and restore sensitivity of cancer cells to EGFR inhibitors. Combinations of a clusterin inhibitor and an EGFR as well as their use in treatment of cancer are thus provided herewith.
US09822169B2 Compositions and methods of use for determination of HE4a
The invention includes the use of the HE/HE4a markers to assess ovarian cancer in a subject. Included also are compositions and methods of using HE/HE4a marker for diagnosis, grading and staging of ovarian cancers, determining prognosis and treatment effectiveness of a subject who has been diagnosed with ovarian cancer.
US09822166B2 Flavivirus neutralizing antibodies and methods of use thereof
The present invention provides antibodies that neutralize flavivirus and methods of use thereof. These antibodies are derived from mAb1 1 which recognizes West Nile virus E protein and is cross-reactive with members of the flavivirus family, including Denge virus. The antibodies of the present invention prevent antibody-dependent enhancement of a viral infection by having a modified Fc region that does not bind to the Fcy receptor. The invented antibody is used to treat flaviviral infections and symptoms thereof.
US09822164B2 Labelling agent, and composition for labelling a protein, method for labelling a protein, and method for detecting a protein
Provided are a labelling agent including a compound of the following Formula 1, a labelling composition, a method of labelling a protein with the labelling agent, and a method of detecting the protein using the labelling agent: wherein R1, R2, R3, R4, R5, R6, and R8 are independently H, substituted or unsubstituted —C1-10-alkyl-, —C2-10-alkenyl, or —C2-10-alkynyl, R7 is H or —NR9R10, R9 and R10 are independently H, substituted or unsubstituted —C1-10-alkyl-, —C2-10-alkenyl, or —C2-10-alkynyl, X is —NR11, —O, or S, R11 is H, substituted or unsubstituted —C1-10-alkyl-, —C2-10-alkenyl, or —C2-10-alkynyl, Y is —OR12 or —NR13R14, R12 is H, substituted or unsubstituted —C1-10-alkyl-, —C2-10-alkenyl, or —C2-10-alkynyl, and R13 and R14 are independently H, substituted or unsubstituted —C1-10-alkyl-, —C2-10-alkenyl, or —C2-10-alkynyl.
US09822163B2 High affinity NY-ESO T cell receptors
The present invention provides T cell receptors (TCRs) having the property of binding to SLLMWITQC-HLA-A*0201, the SLLMWITQC SEQ ID NO:126 peptide being derived from the NY-ESO-1 protein which is expressed by a range of tumour cells. The TCRs have a KD for the said peptide-HLA complex of less than or equal to 1 μM and/or have an off-rate (koff) of 1×10−3 S−1 or slower.
US09822162B2 Anti-human papillomavirus 16 E6 T cell receptors
Disclosed is a T cell receptor (TCR) having antigenic specificity for an HLA-A2-restricted epitope of human papillomavirus (HPV) 16 E6, E629-38. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, and populations of cells are also provided. Antibodies, or an antigen binding portion thereof, and pharmaceutical compositions relating to the TCRs of the invention are also provided. Also disclosed are methods of detecting the presence of a condition in a mammal and methods of treating or preventing a condition in a mammal, wherein the condition is cancer, HPV 16 infection, or HPV-positive premalignancy.
US09822159B2 Electromagnetic band gap element, electronic circuit, and conductor structure
An electromagnetic band gap element is provided. In the electromagnetic band gap element, a first planar conductor and a second planar conductor are respectively formed on a first plane and a second plane which are parallel to each other, and a first linear conductor is formed on at least one third plane that is parallel to the first plane and the second plane and is located between the first plane and the second plane. The first planar conductor and the second planar conductor are connected via the first linear conductor.
US09822156B2 Amyloid beta expression constructs and uses therefor
Disclosed are yeast expression constructs encoding a polypeptide containing a signal sequence, a Golgi-directing pro sequence, and a human amyloid beta protein, and mammalian expression constructs encoding a polypeptide containing a selected signal sequence and a human amyloid beta protein. Also disclosed are methods of screening cells to identify compounds that prevent or suppress amyloid beta-induced toxicity and genetic suppressors or enhancers of amyloid beta-induced toxicity. Compounds identified by such screens can be used to treat or prevent neurodegenerative disorders such as Alzheimer's disease.
US09822155B2 Method of preventively treating a subject at the risk of developing infections of a respiratory virus
A method of preventively treating a subject at the risk of developing infections of a respiratory virus is disclosed. The method includes a step of administering to the subject an effective amount of a peptide synthesized through a chemical route or by a genetic engineering process, characterized in that the peptide has a functional domain capable of binding to a surface glycoprotein of a respiratory virus and has an activity of inhibiting infection of the respiratory virus, wherein the peptide has 5 or more basic amino acids, among which 2 or more basic amino acids are in N-terminal region or C-terminal region of the peptide; and wherein the peptide consists of an amino acid sequence that is at least 90% identical to SEQ ID NO: 10. The invention also discloses the mechanism of the peptides in inhibition of said infections, which provides theory support for developing new prophylactic/therapeutic agents with broad-spectrum antiviral activities.
US09822150B2 Neisseria meningitidis compositions and methods thereof
In one aspect, the invention relates to a composition including a first polypeptide having the sequence set forth in SEQ ID NO: 1 and a second polypeptide having the sequence set forth in SEQ ID NO: 2. In one embodiment, the composition includes about 120 μg/ml of a first polypeptide including the amino acid sequence set forth in SEQ ID NO: 1, 120 μg/ml of a second polypeptide including the amino acid sequence set forth in SEQ ID NO: 2, about 2.8 molar ratio polysorbate-80 to the first polypeptide, about 2.8 molar ratio polysorbate-80 to the second polypeptide, about 0.5 mg/ml aluminum, about 10 mM histidine, and about 150 mM sodium chloride. In one embodiment, a dose of the composition is about 0.5 ml in total volume. In one embodiment, two-doses of the composition induce a bactericidal titer against diverse heterologous subfamily A and subfamily B strains in a human.
US09822145B2 Methods of making carfilzomib and intermediates thereof
Racemization-free methods are disclosed for the synthesis of carfilzomib. Novel intermediates and methods of making carfilzomib employing fragment condensation using the novel intermediates are disclosed. Amorphous carfilzomib and methods of making same are disclosed.
US09822143B2 Removal of high molecular weight aggregates using hydroxyapatite chromatography
This invention relates to the application of hydroxyapatite chromatography to the purification of at least one antibody from a preparation containing high molecular weight aggregates. Further, this invention relates to an integration of ceramic hydroxyapatite chromatography into a combination chromatographic protocol for the removal of high molecular weight aggregates from an antibody preparation.
US09822141B2 N-alkyl 2-(disubstituted)alkynyladenosine-5-uronamides as A2A agonists
The present invention provides N-alkyl 2-(disubstituted)alkynyladenosine-5′-uronamides and derivatives thereof and pharmaceutical compositions containing the same that are selective agonists of A2A adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
US09822139B2 Pharmaceutical composition containing cyclometalated N-heterocyclic carbene complexes for cancer treatment
The present disclosure is related to a pharmaceutical composition for treatment of cancer comprising a cyclometalated N-heterocyclic carbene complex. The cyclometalated N-heterocyclic carbene complex contains a gold(III) or a platinum(II) atom. The pharmaceutical composition possesses anti-cancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of topoisomerase and/or poisoning of topoisomerase.
US09822138B2 Antiviral beta-amino acid ester phosphodiamide compounds
Compounds of Formula I: and their pharmaceutically acceptable salts are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.
US09822137B2 Phosphonucleosides useful in the treatment of viral disorders
A first aspect of the invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or prodrug thereof, wherein the groups are as defined in the claims. Further aspects of the invention relate to pharmaceutical compositions comprising compounds of formula (I), and the use of compounds of formula (I) in the preparation of a medicament for treating a viral disorder.
US09822135B2 STAT3 dimerization inhibitors
The subject matter disclosed herein relates to compositions and methods of making and using the compositions. In a further aspect, the subject matter disclosed herein relates to inhibitors of STAT3 dimerization. Methods of making these compositions as well as compositions comprising these compositions are also disclosed. Also disclosed are methods of treating or preventing certain cancers by administering to an individual in need thereof and effective amount of the compounds disclosed herein. Still further, disclosed herein are methods of inhibiting STAT3 by contacting a cell with a compound or composition as disclosed herein.
US09822133B2 Organic light-emitting device
Provided is an organic light-emitting device including a first electrode, a second electrode, an emission layer between the first electrode and the second electrode, and a hole transport region between the first electrode and the emission layer, wherein the hole transport region includes an auxiliary layer, the auxiliary layer including at least one amine-based compound represented by Formula 1: where R11, R12, R13, R14, R15, R16, X11, L11, L12, L13, a11, a12, a13, b15, and b16 are as defined in the specification.
US09822131B2 Certain chemical entities, compositions and methods
Chemical entities that modulate PI3 kinase activity, and chemical entities, pharmaceutical compositions, and methods of treatments of diseases and conditions associated with P13 kinase activity are described herein.
US09822130B2 Triazolo-pyrazinyl derivatives useful as soluble guanylate cyclase activators
A compound of Formula I or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate (“cGMP”) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of Formula I, or a pharmaceutically acceptable salt thereof, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical compositions which comprise compounds of Formula I or a pharmaceutically acceptable salt thereof.
US09822129B2 Amido spirocyclic amide and sulfonamide derivatives
Provided are amido spirocyclic amide and sulfonamide compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.
US09822126B1 Substituted 1,2,3-triazol-1-yl-methyl-2,3-dihydro-2-methyl-6-nitroimidazo[2,1-b]oxazoles as anti-mycobacterial agents and a process for the preparation thereof
The present invention relates to new generation of triazole functionality containing 6-nitro-2,3-dihydroimidazooxazole agents for general formula I, their method of preparation and their use as drugs for treatment of tuberculosis, MDR-TB and XDR-TB either alone or in combination with other anti-tubercular agents. In general formula 1, X is selected from a group (CH2)n or a direct bond, where n is any number from 1-6, Y is selected from O, S or direct bond, R1 is selected from the group consisting of H, alkyl, substituted alkyl, aryl, substituted aryl, biaryl, substituted biaryl, heterocyclic and substituted heterocyclic, wherein the substituted heterocyclic is selected from any of the following rings consisting of piperazinyl, morpholinyl, piperidyl, pyridyl, triazolyl, triazinyl, pyrimidinyl, pyridazinyl, oxazolyl, furanyl, benzofuranyl, thiophenyl, pyrrolyl, imidazoyl, thiazoyl, quinolinyl, isoquinolinyl, benzooxazolyl and benzothiazolyl and the substitution on aryl and biaryl is selected from the group consisting of F, CI, Br, I, CF3, OCF3, OR11, NO2 and alkyl chain from C1 to C14, wherein R11 is selected from the group consisting of H, alkyl, phenyl and substituted phenyl.
US09822125B2 Benzopyran compounds as melanogenesis modifiers and uses thereof
Provided are benzopyran compounds of formula I, for example, pomiferin-3′,4′-dimethyl ether, and the use of such compounds and compositions thereof to modulate (e.g., inhibit) melanogenesis and pigmentation. wherein R3, R4, R5, R6, R7 and R8 are described herein. Also provided are plant extracts containing a compound of formula I, and the use of such a plant extract to modulate (e.g., inhibit) melanogenesis and pigmentation. The compound or plant extract may be prepared as pharmaceutical and cosmetic compositions, and may be used for the prevention and treatment of conditions that are related to aberrant melanogenesis activity.
US09822120B2 Protein kinase inhibitors
The present invention relates to a novel family of protein kinase inhibitors of Formula I: as well as to the processes of preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative, inflammatory, autoimmune or infectious diseases, disorders, or conditions in which protein kinase activity is implicated.
US09822116B2 Process and intermediates for the synthesis of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compounds
This application discloses a novel process to synthesize 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compounds, which may be used, for example, as NK-1 inhibitor compounds in pharmaceutical preparations, intermediates useful in said process, and processes for preparing said intermediates; also disclosed is a process for removal of metals from N-heterocyclic carbine metal complexes.
US09822113B2 Tricyclic compounds and process for preparation thereof
The present invention relates to novel tricyclic compounds of formula (I) and (II) More particularly, the present invention relates to novel tricyclic compounds of formula (I) and (II) and process of preparation of these compounds from 4,5-di-methyl-o-phenylinediamine. Further, the present invention relates to a process for preparation of tricyclic compound hunanamycin A.
US09822111B2 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer
The specification generally relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, where Q, R1, R2, R3, R4 and R5 have any of the meanings defined herein. The specification also relates to the use of such compounds and salts thereof to treat or prevent ATM kinase mediated disease, including cancer. The specification further relates to crystalline forms of compounds of imidazo[4,5-c]quinolin-2-one compounds and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds and salts; kits comprising such compounds and salts; methods of manufacture of such compounds and salts; intermediates useful in the manufacture of such compounds and salts; and to methods of treating ATM kinase mediated disease, including cancer, using such compounds and salts.
US09822110B2 Sulfonamide derivative and pharmaceutical use thereof
Provided is a sulfonamide derivative represented by the following general formula (1) and having an α4 integrin inhibitory effect with high selectivity with a low effect on α4β1 and a high effect on α4β7, or a pharmaceutically acceptable salt thereof (in the general formula (1), A, B, D, E, R41, and a to h are as described in the description).
US09822102B2 Substituted oxopyridine derivatives and use thereof in the treatment of cardiovascular disorders
The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
US09822100B2 Aryl-substituted imidazoles
The compounds of the invention are antagonists of MDM2 and MDMX, with excellent specificity for MDM2 and MDMX over other proteins, and with selective binding affinity to MDMX over MDM2. The compounds can therefore regulate p53 activity and treat a variety of cancers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US09822098B2 Compounds targeting proteins, compositions, methods, and uses thereof
The present invention provides modulators of protein function, to restore protein homeostasis, including cytokine, aiolos, and/or ikaros activity, and cell-cell adhesion. The invention provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other cytokine and inflammatory mediators, are provided. Methods of treatment, amelioration, or prevention of protein-mediated diseases, disorders, and conditions, such as cytokine-mediated diseases, disorders, and conditions, including inflammation, fibromyalgia, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, psoriasis, psoriatic arthritis, inflammatory bowel diseases, Crohn's disease, ulcerative colitis, uveitis, inflammatory lung diseases, chronic obstructive pulmonary disease, Alzheimer's disease, and cancer, are provided.
US09822095B2 Tetrazolinone compound and application thereof
A tetrazolinone compound represented by formula (1): wherein R1 and R2 each independently represents a hydrogen atom, a C1-C4 alkyl group optionally having one or more halogen atoms, etc.; R3 represents a hydrogen atom, a C1-C4 alkyl group optionally having one or more halogen atoms, etc.; R4 represents a halogen atom, a C1-C4 alkyl group optionally having one or more halogen atoms, etc.; h represents any one of integers of 0 to 4; X represents a nitrogen atom or CR5; and R5 represents a hydrogen atom, a halogen atom, etc.; has excellent control activity against pests.
US09822094B2 Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same
Provided are 4′-arylmethoxy isoindoline compounds, and pharmaceutically acceptable salts, solvates, clathrates, stereoisomers, and prodrugs thereof. Methods of use, and pharmaceutical compositions of these compounds are disclosed.
US09822092B2 ArylSulfonamide-based matrix metalloprotease inhibitors
The present invention provides a compound of formula (I): said compound is inhibitor of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12, and/or MMP-13. Finally, the present invention also provides a pharmaceutical composition.
US09822090B2 Method for producing nebivolol hydrochloride of high purity
The invention relates to a process for producing Nebivolol hydrochloride, (formula I) comprising the steps of: provision of a protected Nebivolol hydrochloride of the general formula (II), with P being an amine protecting group, and hydrogenation of said protected Nebivolol hydrochloride yielding Nebivolol hydrochloride of the formula (I).
US09822078B2 Quinoline compounds
The present invention relates to quinoline compounds as defined by Formula I below. Such quinoline compounds have been shown to inhibit the formation of amyloid deposits (e.g., amyloid oligomers, fibrils or plaques). Consequently, these compounds are suitable for treating a range of diseases and disorders in which amyloid deposits are implicated, such as type-2 diabetes and Alzheimer's disease.
US09822070B2 Methods of manufacture of 2-hydrocarbyl-3,3-bis(hydroxyaryl)phthalimidines
A method for the manufacture of a 2-hydrocarbyl-3,3-bis(hydroxyaryl)phthalimidine composition comprises: reacting a phthalimide with a phenol in the presence of a catalyst and optionally a solvent at an elevated temperature to form the 2-hydrocarbyl-3,3-bis(hydroxyaryl)phthalimidine composition.
US09822069B2 Urea derivative or pharmacologically acceptable salt thereof
Provided is a compound having a formyl peptide receptor like 1 (FPRL1) agonist effect.The present invention relates to a compound represented by the general formula (I) or a pharmacologically acceptable salt thereof. The present invention also relates to a pharmaceutical composition containing the compound represented by the general formula (I) or a pharmacologically acceptable salt thereof.
US09822066B2 Tranilast compositions and cocrystals
New tranilast complexes and new tranilast cocrystals are disclosed. These include a 1:1 tranilast nicotinamide complex, a 1:1 tranilast nicotinamide cocrystal, a 1:1 tranilast saccharin complex, a 1:1 tranilast saccharin cocrystal, a 1:1 tranilast gentisic acid complex, a 1:1 tranilast gentisic acid cocrystal, a 1:1 tranilast salicylic acid complex, a 1:1 tranilast salicylic acid cocrystal, a 1:1 tranilast urea complex, a 1:1 tranilast urea cocrystal, a 1:1 tranilast 4-aminobenzoic acid complex, a 1:1 tranilast 4-aminobenzoic acid cocrystal, a 1:1 tranilast 2,4-dihydroxybenzoic acid complex and a 1:1 tranilast 2,4-dihydroxybenzoic acid cocrystal. Also disclosed are pharmaceutical compositions containing a tranilast complex or cocrystal of the invention and a pharmaceutically acceptable carrier. Methods of treatment using the tranilast complexes and cocrystals as well as the pharmaceutical compositions are disclosed.
US09822065B1 Benzazepine dicarboxamide compounds
This invention relates to novel benzazepine dicarboxamide compounds of the formula wherein R1 to R4 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are TLR agonists and may therefore be useful as medicaments for the treatment of diseases such as cancer, autoimmune diseases, inflammation, sepsis, allergy, asthma, graft rejection, graft-versus-host disease, immunodeficiencies, and infectious diseases.
US09822061B2 Method for producing nitro compound
A compound represented by formula (1): can be produced by: a step wherein a compound represented by formula (2): is reacted with a compound represented by formula (3): thereby obtaining a compound represented by formula (4): a step wherein a compound represented by formula (4) is reacted with hypohalogenous acid or a salt thereof, thereby obtaining a compound represented by formula (5): and a step wherein a compound represented by formula (5) is reduced.
US09822060B2 Compound, resin, resist composition and method for producing resist pattern
A compound having a group represented by the formula (Ia): wherein R1 represents a C1 to C8 fluorinated alkyl group, R2 represents a group having an optionally substituted C5 to C18 alicyclic hydrocarbon group, and * represents a binding site.
US09822057B2 Solid forms of treprostinil
There is provided individual polymorphic forms of treprostinil and pharmaceutical formulations comprising the same, methods of making and using the same.
US09822053B2 Single step conversion of N-butyraldehyde to 2-ethylhexanal
Disclosed is a method of making and using a titania supported palladium catalyst for the single step synthesis of 2-ethylhexanal from a feed of n-butyraldehyde. This titania supported palladium catalyst demonstrates high n-butyraldehyde conversion but also produces 2-ethylhexanal in an appreciable yield with maintained activity between runs. This method provides a single step synthesis of 2-ethylhexanal from n-butyraldehyde with a catalyst that can be regenerated that provides cleaner downstream separations relative to the traditional caustic route.
US09822051B2 Method for producing acrolein
The present invention relates to a process for preparing acrolein from propylene by catalytic gas phase oxidation with molecular oxygen (for example air). The invention further relates to the use of particular propylene-containing starting materials, for example refinery grade propylene, for preparation of acrolein.
US09822045B2 Additive manufactured thermoplastic-aluminum nanocomposite hybrid rocket fuel grain and method of manufacturing same
A hybrid rocket solid fuel grain having a cylindrical shape and defining a center port is additive manufactured from a compound of thermoplastic fuel and passivated nanocomposite aluminum additive. The fuel grain comprises a stack of fused layers, each formed as a plurality of fused abutting concentric circular beaded structures of different radii arrayed defining a center port. During operation, an oxidizer is introduced along the center port, with combustion occurring along the exposed port wall. Each circular beaded structure possesses geometry that increases the surface area available for combustion. As each layer ablates the next abutting layer, exhibiting a similar geometry is revealed, undergoes a gas phase change, and ablates. This process repeats and persists until oxidizer flow is terminated or the fuel grain material is exhausted. To safety achieve this construction, a fused deposition additive manufacturing apparatus, modified to shield the nanocomposite material from the atmosphere is used.
US09822044B2 Urease inhibitor formulations
The present disclosure provides a liquid composition, comprising a dialkylcarbonate, and one or more phosphoric triamide compounds. Also provided is a liquid composition, comprising a C1-C4 alcohol, a vegetable oil or petroleum distillate, a surfactant, and one or more phosphoric triamide compounds. A further aspect of the disclosure provides a method for treating a nitrogen-containing fertilizer, comprising contacting a nitrogen-containing fertilizer with the liquid compositions described herein.
US09822039B1 Metal oxide ceramic nanomaterials and methods of making and using same
Provided are metal oxide ceramic materials and intermediate materials thereof (e.g., nanozirconia gels, nanozirconia green bodies, pre-sintered ceramic bodies, zirconia dental ceramic materials, and dental articles). The nanozirconia gels are formable gels. Also provided are methods of making and using the metal oxide materials and intermediate materials. The nanozirconia gels can be made using, for example, osmotic processing. The nanozirconia gels can be used to make nanozirconia green bodies, pre-sintered ceramic bodies, zirconia dental ceramic materials, and dental article. The nanozirconia green bodies, pre-sintered ceramic bodies, zirconia dental ceramic materials, and dental articles have desirable properties (e.g., optical properties and mechanical properties).
US09822028B2 Methods of processing a glass ribbon
Methods of processing a glass ribbon are provided. The method includes the step of traversing the glass ribbon through a travel path at a predetermined velocity and severing the glass ribbon to create an upstream web and a downstream web. The method further includes the step of increasing a relative velocity of a downstream edge portion with respect to an upstream edge portion to create a gap between an upstream severed edge and a downstream severed edge. In other example methods, a segment of the glass ribbon is removed to create a gap between an upstream severed edge and a downstream severed edge. In still further example methods, an upstream severed edge is directed along a second travel path to create a gap between the upstream severed edge and a downstream severed edge.
US09822025B2 Method for treating soil-contaminating water using photocatalytic material
The present invention provides a novel method for treating soil-contaminated water, the method using a photocatalytic material capable of efficiently removing, by light irradiation alone, volatile organic compounds and heavy metals that give rise to soil contamination. The present invention provides a method for treating soil-contaminated water that detoxifies volatile organic compounds contained in soil-contaminated water using a photocatalytic material, the method being characterized by including the steps of (1) subjecting the soil-contaminated water to a gas-liquid separation to obtain a gas phase, and (2) decomposing the volatile organic compounds contained in the gas phase obtained in step (1) using the photocatalytic material. The present invention further provides a method for treating soil-contaminated water using a photocatalytic material to remove heavy metals contained in the soil-contaminated water, the method being characterized, by including the steps of (1) subjecting the soil-contaminated water to a gas-liquid separation to obtain a liquid phase, and (2) removing the heavy metals contained in the liquid phase obtained in step (1) using the photocatalytic material.
US09822021B2 Forward osmosis separation processes
Separation processes using forward osmosis are disclosed generally involving the extraction of a solvent from a first solution to concentrate a solute therein by using a second concentrated solution to draw the solvent from the first solution across a semi-permeable membrane. One or both of the solute and solvent may be a desired product. By manipulating the equilibrium of the soluble and insoluble species of solute within the second solution, a saturated second solution can be used to generate osmotic pressure on the first solution. The various species of solute within the second solution can be recovered and recycled through the process to affect the changes in equilibrium and eliminate waste products. Enhanced efficiency may result from using low grade waste heat from industrial or commercial sources.
US09822020B2 Nutrient recovery process
An apparatus for recovering nutrients or water from digestate comprises one or more solid-liquid separation units, an ammonia stripping device, and a gas scrubbing unit. In a process, digestate is separated into a solids portion and a liquid portion. Ammonia is stripped from the liquid portion and converted into an ammonium salt solution which may be sold or used as, or blended with, a fertilizer product. Optionally, at least part of the remaining liquid portion may be concentrated to produce brine. The brine is mixed with the solids portion. The mixture may be dried and used as, or blended with, a fertilizer product. Optionally, a least part of the remaining liquid portion may be re-used as dilution water in a digester. A solids portion of the digestate, and one or both of an ammonium salt solution and a brine, may be used as fertilizer without thermal drying.
US09822019B2 Desalination system and desalination method
A desalination system includes a water tank, a water-repellent particle layer located at a lower portion of the tank and composed of water-repellent particles, and a devolatilizing layer located below the water-repellent particle layer. Liquid is introduced to the tank, the introduced liquid is heated to be evaporated into water vapor, and the water vapor passes through the water-repellent particle layer and is liquefied at the devolatilizing layer, so that fresh water is obtained from the liquid. The desalination system further includes a liquid level controller for determining a level of the liquid introduced to the tank in accordance with information on relationship between information corresponding to an amount of the liquid introduced to the tank and a surface level of the liquid in the tank, and an introduced amount controller for adjusting the amount of the liquid introduced to the tank in accordance with the determined liquid surface level.
US09822018B2 Water amount controlling method and desalination system
A water amount controlling method according to the present disclosure includes: opening a discharge valve that discharges a liquid from a water tank if an impurity concentration is higher than or equal to a first reference value, and opening a sluice gate that introduces the liquid to the water tank a predetermined period after opening the discharge valve, the first reference value being lower than a saturation concentration; throttling the discharge valve and the sluice gate if the impurity concentration is higher than or equal to a second reference value and the temperature is lower than or equal to a third reference value, the second reference value being lower than the first reference value; and closing the discharge valve if the impurity concentration is lower than the second reference value, and closing the sluice gate a predetermined period after closing the discharge valve.
US09822013B1 Selective mining enhanced recovery process
Some embodiments of the present disclosure include a method and method for recovery of solution mined minerals. The method may include creating superheated steam using a steam boiler; passing the superheated steam through a turbine/generator to generate electricity; reheating the steam exiting the turbine/generator to saturation with a steam reheater; using the saturated steam with an absorption chiller to create chilled water; and recovering minerals using the chilled water in a cooling crystallizer system. In embodiments, the method and system may be used to recover minerals, such as potash (KCl), washing soda (Na2CO3.10H2O); nahcolite (NaHCO3); and glauber salt (NaSO4.10H2O). The method may utilize the trigeneration of steam, electrical, and chilled water utilities, which may be used for a recovery process.
US09822009B2 Method for producing graphene
A graphene producing method which is capable of increasing a size of each domain of graphene. A plasma CVD film formation device that activates a catalyst metal layer formed on a wafer; modifies the same into an activated catalyst metal layer; decomposes a C2H4 gas as a low reactivity carbon-containing gas by plasma in a space that opposes the wafer; and decomposes a C2H2 gas as a high reactivity carbon-containing gas by heat in the space.
US09822004B2 Hydrogen generator with locking door
Disclosed is a hydrogen generator with a door that can be opened to replace a fuel unit and closed to seal the door. A lock responds directly to pressure within the chamber to prevent opening when the pressure exceeds a threshold value. The lock includes a locking member with a lug that engages a retainer to seal the door when the door is locked and is disengaged from the retainer when the door is unlocked. An opening mechanism moves the locking member to lock and unlock the door. A movable key is engaged with the opening mechanism and the locking member when the pressure in the chamber is at or below the threshold value and disengaged from one of the opening mechanism and the locking member by an actuator (e.g., a flexible diaphragm) so the door cannot be unlocked and opened when the pressure is above the threshold value.
US09822003B2 Process and apparatus for molten slag gasification of solid fuels
A process and an apparatus for molten slag gasification of solid fuels in a molten slag gasifier with increased output, an increased range of solid fuels that can be used and improved gas quality. The process is conducted such that, by means of a molten slag gasifier comprising a feed of the coarse-grained solid fuels and comprising a gas takeoff, both at the head of the molten slag gasifier, comprising a slag bath and comprising a slag bath takeoff at the bottom of the molten slag gasifier, comprising a feed for first gasifying means by means of gasifying means nozzles above the slag bath, comprising a filling of the fixed bed above the slag bath, in addition to the first gasifying means a second gasifying means are injected by way of at least one gasifying means nozzle that reaches into the upper region of the fixed bed.
US09822002B1 Flexible electronics for wearable healthcare sensors
Aspects include a method of manufacturing a flexible electronic structure that includes a metal or doped silicon substrate. Aspects include depositing an adhesive layer on the top side of the structure. Aspects also include depositing a release layer and a glass layer on the top side of the structure. Aspects also include reducing a thickness of the silicon substrate on the bottom side of the structure.
US09822001B2 Process for manufacturing a lid for an electronic device package, and lid for an electronic device package
A process for manufacturing a packaged microelectromechanical device includes: forming a lid having a face and a cavity open on the face; coating the face of the lid and walls of the cavity with a metal layer containing copper; and coating the metal layer with a protective layer.
US09822000B2 MEMS and CMOS integration with low-temperature bonding
The present disclosure relates an integrated chip having one or more MEMS devices. In some embodiments, the integrated chip has a carrier substrate with one or more cavities disposed within a first side of the carrier substrate. A dielectric layer is disposed between the first side of the carrier substrate and a first side of a micro-electromechanical system (MEMS) substrate. The dielectric layer has sidewalls that are laterally set back from sidewalls of openings extending through the MEMs substrate to the one or more cavities. A bonding structure, including an intermetallic compound having a plurality of metallic elements, abuts a second side of the MEMS substrate and is electrically connected to a metal interconnect layer within a dielectric structure disposed over a CMOS substrate.
US09821996B2 Beverage dispensing apparatus and method
A beverage dispensing apparatus with a dispenser compartment, a flexible concentrate bag with a first opening through which a beverage concentrate is introduced at a production site and optionally a second opening at the top of the bag. The second opening is used at the dispensing location to introduce a diluent into the bag. A low acid beverage concentrate is contained in the bag. A beverage homogenizing agitator subassembly is situated inside the dispenser compartment. A beverage dispensing subassembly includes a sealed fitting located at the bottom region of the bag and a tube extending therefrom. The beverage dispensing apparatus reduces shipping and maintenance costs due to shipping concentrate rather than a finished beverage while enhancing sanitation.
US09821989B2 Adjustable overhead assembly for vehicle lift
An apparatus for lifting a vehicle comprises at least two posts, at least two lifting assemblies, at least one actuator, and an overhead assembly. The at least two posts are configured to cooperatively raise a vehicle. Each lifting assembly is associated with a corresponding post. The at least two lifting assemblies are configured to move simultaneously to raise a vehicle. The at least one actuator is in communication with the at least two lifting assemblies. The overhead assembly is secured to each of the at least two posts such that the overhead assembly extends from one post to another post. The overhead assembly is selectively movable relative to the at least two posts between a first position and a second position.
US09821987B2 Adjustable universal adaptor for a lifting jack
An adaptor is provided for a jack assembly having a lifting jack carrying a horizontal plate for raising and lowering a heavy component supported by the jack assembly. The adaptor includes a horizontal support plate fastened to and vertically offset from the horizontal plate of the jack assembly by a height. A plurality of elongated arms is slidably mounted between the two plates to move in a generally horizontal plane. Each of arms includes a holding assembly configured to engage portions of the component supported on the support plate to stabilize the component as it is raised and lowered by the jack assembly. The arms are supported in the height between the two plates at different heights so that the arms are capable of a wide range of rotational and linear movements to adjust the position of the holding assembly of each arm relative to the heavy component.
US09821986B2 Vehicle wheel with self-rescue apparatus
A vehicle wheel with self-rescue apparatus contains: a connecting disc and a winch device. The connecting disc includes a body, a protruded column, elongated locking orifices, fitting sleeves, through orifice, connection stems, and multiple fixing plates. Each locking orifice locks with each of plural nuts, and each connection stem has a tab and a threaded section for screwing with a screwing orifice on each fixing plate via one of the through orifices, and each fixing plate contacts with the wheel rim, after the threaded section screws with the screwing orifice via the one through orifice. The winch device includes a rolling disc, the accommodating opening, a passing opening, a cable, and a hooking portion. The rolling disc has the accommodating opening, and a profile of the accommodating opening corresponds to the protruded column, the rolling disc has the cable rolled thereon, and the cable has the hooking portion arranged thereon.
US09821985B2 Crane having a modular undercarriage
The invention relates to a crane having an undercarriage with a swivel connection and having a superstructure rotatably supported thereon via the swivel connection and comprising at least one boom system arranged at said superstructure and luffable about a luffing axis or a self-climbing tower slewing crane rotatably supported thereon via the swivel connection. In accordance with the invention, the undercarriage has a pot as a central component which, on the one hand, receives the swivel connection. Furthermore, however, the pivotable supports can also be pivotally connected to it. Side members are present at mutually oppositely disposed sides and at least one traveling gear can respectively connected to them with at least one degree of freedom.
US09821979B2 Support device for an elongate article
The invention concerns a capstan reel (10) and a method for transporting an elongated article (6, 6a, 6b, 39, 42, 43, 45a, 47) between a floating vessel (2) and a body of water situated below the vessel, and a vessel applying such a capstan reel. The capstan reel comprises a rotatable cylindrical body (100) for spooling the elongated article around the body's axial axis (11), said body comprising a cylindrical contacting surface (35) for indirectly supporting at least a portion of the elongated article. Furthermore, the capstan reel comprises an endless chain (18) spooled at least partly around the cylindrical body in a helical direction relative to the axial axis of the body, acting as an intermediate layer between the cylindrical contacting surface and the intended elongated article, and a chain transfer guide (17) extending across the axial length of the cylindrical body for guiding the endless chain between a chain exit region (T) in a first axial end region (7a) of the cylindrical body and a chain entry region (E) in a second axial end region (7b), the second axial end region being situated at the opposite axial end of the cylindrical body.
US09821975B2 Tape feeder and tape setting method
A second tape feeding mechanism 20B is permitted to idly rotate only in a first rotating direction and has a biasing mechanism 25 which biases a carrier tape 14 against a sprocket 21B so that the carrier tape 14 is brought into engagement with the sprocket 21B. With a preceding tape 14(1) kept in engagement with the sprocket 21B, a leading end portion of a following tape 14 (2) is inserted between the sprocket 21B and the preceding tape 14 (1), and the preceding tape 14 (1) is biased by the biasing means 25 so that the following tape 14(2) is brought into engagement with the sprocket 21B.
US09821973B2 Image forming apparatus comprising a sheet feed unit removably mounted
An image forming apparatus includes an apparatus main body, a sheet storage cassette, a sheet feed unit, a first detection sensor having a first detector for detecting the presence/absence of sheets stacked on a sheet stacking plate, a second detection sensor having a second detector for detecting the position of the top face of the sheets stacked on the sheet stacking plate, a cassette detection sensor, a driving device, and a controller. The sheet feed unit includes a first actuator for switching detection states of the first detection sensor and a second actuator for switching detection states of the second detection sensor. The controller determines the mounting state of the sheet feed unit based on the detection state of the first and second detection sensors.
US09821971B2 Sheet feed device and image recording apparatus having such sheet feed device
An image recording apparatus including a first tray having a first holding portion for holding sheets, a second tray disposed above the first tray and including a second holding portion for holding sheets, a sheet feeder that selectively feeds a sheet from one of the first tray and the second tray in a sheet feed direction, a recording unit that records an image on the sheet fed by the sheet feeder, and a discharge roller that discharges the sheet on which the image is recorded by the recording unit. The second holding portion of the second tray moves above the first holding portion of the first tray. The second tray further includes a discharged sheet receiving portion for receiving the sheet discharged by the discharge roller. The second tray including the discharged sheet receiving portion pivots relative to the first tray.
US09821970B2 Sheet feeder and image forming system
A sheet feeder including a tray, a feeder roller, a guide, a separator, a motor, a controller, and a sensor, is provided. The sheet feeder separates an object sheet from other sheets in the tray and feed the object sheet through the guide and the separator by rotation of the feeder roller. The controller determines a remaining volume of the sheets in the tray based on a signal from the sensor; generate a velocity profile so that the object sheet is fed at a lower velocity in an earlier first period than a velocity in a later second period; based on the determined remaining volume of the plurality of sheets, modify at least one of a length of the first period and the target velocity in the first period of the velocity profile; and after modification of the velocity profile, control the motor in compliance with the modified velocity profile.
US09821961B2 Adjustable conveying device
A device and method of adjusting a spacing of holders located on first and second endless loop includes releasing a clutch to allow the endless loops to be adjusted and operating an adjustment assembly to simultaneously move the first endless loop a distance in a first direction and the second endless loop an equal distance in a second direction opposite the first direction. After the adjustment the timing and pitch of the center of articles gripped by the holders is unchanged relative to the system in which the device is located.
US09821953B2 Apparatus for sealing a vacuum tank door
An apparatus for sealing a vacuum tank door. The apparatus comprises a circular flange attached to a door panel of a vacuum tank, a horizontal crossbar connected to the center of the door panel and a lifting assembly. The lifting assembly comprises an upper linkage arm, a lower linkage arm, and a hydraulic cylinder. Activation of the hydraulic cylinder causes the linkage assembly to move downwards pulling on the horizontal crossbar and pulling the vacuum tank door towards the tank. Activation of the hydraulic cylinder also causes a connection point of the lower linkage arm and the upper linkage arm to move over-center of the connection between the lower linkage arm to the to the tank creating a tight seal between the vacuum tank door and the tank.
US09821943B2 Detachable fitment
A fitment for a sachet includes a body having a slot that extends from a lower surface of the body toward an upper surface of the body. The upper surface caps the slot in a first portion of the body such that fluid flow is prevented through the first portion of the body in a direction from the lower surface toward the upper surface. The slot connects to an opening in the upper surface in a second portion of the body. A flow path exists through the slot and the opening in the second portion of the body in the direction from the lower surface toward the upper surface.
US09821929B2 Packaging system
Described herein are packaging systems having a receptacle and one or a plurality of expandable members that are configured to move from a collapsed configuration to an expanded configuration. In some variations the expandable member includes one or a plurality of folded pieces of material (e.g., tissue paper or fabric (e.g., tulle)), which are attached to the receptacle. In the expanded configuration, the expandable member(s) obscure an object (e.g., a gift) placed within the receptacle without closing the receptacle.
US09821928B2 Can end
A can end has a public side and an opposing product side. A circumferential curl is located about a center axis and defines an outer perimeter of the can end. A circumferential wall extends downwardly from the curl. A circumferential, generally U-shaped countersink extends radially inwardly from the circumferential wall relative to the center axis and upwardly. A center panel extends radially inwardly from the countersink relative to the center axis and has a displaceable tear panel defined by frangible score and a hinge segment on the public side and a tab fixed to the public side which has a nose portion overlying a portion of the displaceable tear panel. A circumferential panel joins the countersink with the center panel and has a first panel radius joined to a second panel radius by a short wall extending upwardly and inwardly. The circumferential panel has a bead formed therein.
US09821923B2 Method of packaging product units and a package of product units
A package of product units includes an entirely wrapped first product unit including a first product unit completely enveloped in a cover. An entirely wrapped second product unit (i) includes a second product unit completely enveloped in a cover and (ii) is disposed adjacent to the wrapped first product unit. A band disposed around the wrapped first product unit and the wrapped second product unit creates a secured product arrangement A wrapper completely envelopes the band, the wrapped first product unit, and the wrapped second product unit of the secured product arrangement to create a wrapped secured product arrangement, such that the wrapper directly contacts the band The wrapped secured product arrangement consists essentially of wrapped product units, the band, and the wrapper. The cover of the first product unit, the cover of the second product unit, the band, and the wrapper each comprises a plastic material.
US09821920B2 Methods and apparatus for compensating for vehicular motion
A head mounted virtual reality (VR) device including an inertial measurement unit (IMU) is located in a vehicle which may be, and sometimes is, moving. Detected motion attributable to vehicle motion is filtered out based on one or more or all of: vehicle type information, information derived from sensors located in the vehicle external to the head mounted VR device, and/or captured images including a reference point or reference object within the vehicle. An image portion of a simulated VR environment is selected and presented to the user of the head mounted VR device based on the filtered motion information. Thus, the image portion presented to the user of the head mounted VR device is substantially unaffected by vehicle motion and corresponds to user induced head motion.
US09821918B2 Aircraft comprising a control device for a jet pipe nozzle with variable cross-section powered by two independent electrical power supplies
The subject of the disclosure is an aircraft comprising at least one left motor generator, at least one right motor generator, a control device for a jet pipe nozzle with variable cross-section of the aircraft comprising at least one control member powered by a first airplane electrical power supply linked to at least one right or left motor generator, the control member powered by a second electrical power supply linked to an electrical power source of the aircraft independent of the first airplane electrical power supply.
US09821915B2 Method and apparatus for inhibiting formation of and/or removing ice from aircraft components
Methods and systems are generally described that inhibit debris (such as ice) accretions and/or remove debris (such as ice) accretions from the exterior surface of an aircraft. In some embodiments, the invention is a system for an aircraft comprising: a component of the aircraft having a surface; a plurality of piezo-kinetic actuators each positioned proximate to a portion of the surface; and a control unit coupled to the plurality of actuators, the control unit configured to actuate one or more of the actuators at one or more frequencies; wherein the actuators are each configured to introduce a displacement of the surface in three dimensions to inhibit a formation of ice on at least the portion of the surface and to break up existing ice formations on at least the portion of the surface.
US09821912B2 Aircraft galley unit
An aircraft galley unit includes a housing defining an outer shell, and a rack area and a double deck area arranged within the housing, wherein the double deck area includes a hoist-way formed in an interior of the housing, a lifting mechanism moving up and down within an area of the hoist way, and a driving source for moving the lifting mechanism up and down, and the driving source is arranged on a ceiling portion of the housing.
US09821910B1 Unmanned vehicle control system and apparatus
A system for controlling an unmanned aerial vehicle may include a GNSS receiver, a transponder, one or more flight controls, a UAV operation module, a UAV mission module, and a UAV chassis. The system may include an operating area defined within an airspace and an airspace controller, and a transponder key issued to the UAV by the airspace controller. The airspace controller and the UAV may communicate to unlock UAV access of the operating area, including transmitting a transponder ID code for verification to the airspace controller; receiving a read certificate from the airspace controller; transmitting a mission plan to the airspace controller; receiving a mission key from the airspace controller; verifying the mission key via read back transmission to the airspace controller; and receiving a mission plan from the airspace controller in the form of the transponder key, the mission plan unlocking access to the operating area.
US09821909B2 Rotating wing assemblies for tailsitter aircraft
A tailsitter aircraft includes one or more rotatable wings. The tailsitter aircraft optionally includes a fuselage from which wing supports extend. Each rotatable wing optionally includes a rotatable wing section having an inboard portion proximate to the fuselage, and an outboard portion distal from the fuselage. The rotatable wing section may be rotatably attached to the wing support and configured to rotate between a vertical flight configuration in which the inboard portion is positioned on an opposing side of the wing support relative to the outboard portion, and a horizontal flight configuration different from the vertical flight configuration. The wings may be rotated during flight to transition between horizontal and vertical flight configurations, and they may be rotated about multiple axes.
US09821908B2 System and method for assisting in rotor speed control
A method of assisting in rotor speed control in a rotorcraft can include measuring a rotor speed with a sensor; detecting a droop in the rotor speed beyond a lower droop limit; and commanding a decrease in collective in response to the rotor speed drooping beyond the lower droop limit. A system of assisting in rotor speed control in a rotorcraft, the system can include: a computer having a control law, the control law operable to generate a decrease collective command to an actuator in response to a rotor speed decreasing below a lower droop limit; wherein the lower droop limit is below a normal lower rotor speed range.
US09821906B1 Elongated nose structure to provide stability during boarding
A rotor with an elongated nosecone structure to provide stability when boarding or deplaning and to prevent damage to rotor blades is disclosed. A rotor as disclosed herein may include a plurality of rotor blades affixed to the hub structure; and an elongated nose structure extending away from the hub in a direction substantially orthogonal to a deployed direction of said rotor blades, the elongated nose structure having a length greater than a diameter of the elongated nose structure.
US09821905B2 Landing gear drive system
The invention provides a drive system for rotating a wheel of an aircraft landing gear. The drive system includes a motor operable to rotate a drive pinion, and a driven gear adapted to be mounted to the wheel. The drive system has a first configuration in which the drive pinion is capable of meshing with the driven gear to permit the motor to drive the driven gear and a second configuration in which the drive pinion is not capable of meshing with the driven gear. The drive system includes a linear positioning actuator for moving the drive pinion relative to the driven gear. The positioning actuator has a first end and a second end, the first end having a pivotal connection with a pivot axis spaced at a fixed distance from an axis of rotation of the driven gear, and the second end having a pivotal connection with a pivot axis spaced at a fixed distance from an axis of rotation of the drive pinion.
US09821904B2 Landing gear with structural load path diverter bracket
A landing gear support arrangement may comprise a cylinder, a pin pivotally coupled to the cylinder, a head attached to the pin having a portion extending radially from the pin, and a bracket coupled to the portion of the head configured to axially support the pin.
US09821903B2 Closed loop control of aircraft control surfaces
Closed loop control of control surfaces is described herein. One disclosed example method includes measuring a flight metric of an aircraft during flight and calculating, using a processor, a deflection of a control surface of the aircraft based on the flight metric. The disclosed example method also includes adjusting the deflection to an effective deflection level based on the calculated deflection to reduce a drag coefficient of the aircraft.
US09821902B2 High lift control method and system for aircraft
A high lift control system for an aircraft having at least one high lift surface includes a selector having a predetermined number of discrete positions, at least one of the predetermined positions corresponding to different positions of the at least one high lift surface.
US09821898B1 Pedal-powered water propulsion device
A peddle-actuated water propulsion device includes a seat with lower body harness, a support tube, a pair of crank-type pedals, and a propeller within a protective screen guard. The pedals are in mechanical communication with the propeller. The propeller is configured to accept a plurality of differently sized blades and may be positioned at a user-selected angle.
US09821894B2 Autonomous underwater vehicle for marine seismic surveys
An autonomous underwater vehicle (AUV) for recording seismic signals during a marine seismic survey. The AUV includes a body having a flush shape; an intake water element located on the body and configured to take in water; at least one propulsion nozzle located on the body and configured to eject the water from the intake water element for actuating the AUV; at least one guidance nozzle located on the body and configured to eject water to change a traveling direction of the AUV; and a seismic payload located on the body of the AUV and configured to record seismic signals.
US09821889B2 Boat seat accessory stand
A boat seat accessory stand includes a main support member, a sleeve member, a lower brace member, and an upper brace member for attaching an umbrella or other accessory to a typical pedestal mount boat seat. The boat seat accessory stand provides for support and rotation of the attached umbrella around the boat seat.
US09821887B1 Convertible leaning post seating system for marine vessels
A convertible seating system for a marine vessel includes a frame and a seat mounted on the frame and defining a first support surface. A backrest is configured for movement relative to the seat and the frame between a first position and a second position. In the second position, the backrest defines a second support surface lying generally parallel and vertically displaced relative to the first support surface.
US09821885B2 Multihull watercraft
The patent discloses a multihull watercraft with a unique hull configuration providing numerous benefits. Passenger cabins are enclosed within a separate upper hull, which allows the accommodation space and the float hulls to be independently optimized. The new configuration also provides reduced windage, and creates additional deck space for easier boarding, recreational use, and safer access to shore craft.
US09821884B2 Bicycle operating device
A bicycle operating device, having a center axis, comprises a mounting structure configured to be press fitted into a free end of a bicycle handlebar; and an operating structure for an operation of a bicycle component, the operating structure being coupled to the mounting structure.
US09821883B2 Vehicle traction device and vehicle incorporating same
Vehicle traction device, mainly for land vehicles, of the type comprising a motor and a transmission wherein the motor preferably has an axial rotation, such as an electric motor, wherein the motor rotation is coplanar and concurrent with the primary shaft of the transmission, and wherein the primary shaft is in turn coaxial to the output shaft, such that the output shaft crosses the primary shaft and extends beyond the ends thereof.
US09821882B2 Assembling method and assembling management method of electric vehicle
An assembling method of an electric vehicle comprises the steps of: assembling a vehicle body including a frame, wheels and an electric motor; conducting a vehicle body test including confirmation of a state of driving power transmission from the electric motor to the wheels by connecting an electric power supply unit installed in a vehicle body test place to the electric motor of the vehicle body and supplying electric power from the electric power supply unit to the electric motor; detaching the electric power supply unit from the electric motor and transporting the vehicle body which has passed the vehicle body test from the vehicle body test place to a mounting place, in a state in which a battery is not mounted to the vehicle body; and mounting the battery to the transported vehicle body in the mounting place.
US09821874B2 Vehicle
A fan generates an air flow that cools a portion of an engine unit. A ventilation opening causes air flow directed to the fan to pass therethrough. Under a condition that a body frame is in an upright state and a condition that a left front wheel and a right front wheel are not turned by a steering device, the ventilation opening is disposed directly behind a lower cover of an inner fender, ahead of a rear end of a rear wheel, on the right of a left end of the left front wheel, and on the left of a right end of the right front wheel.
US09821871B2 Grip cover
A grip cover for a bicycle control device includes a high durometer portion that is configured to engage the bicycle control device to maintain the grip cover in contact with the bicycle control device. The grip cover further includes a low durometer portion that is connected to the high durometer portion. The low durometer portion is configured to be tensioned by the high durometer portion when the grip cover is installed on the bicycle control device.
US09821869B2 Connection device for a pannier
The present invention relates to a connection device for a pannier for a vehicle and a pannier having such a connection device. The connection device includes a pivotable support member having an attachment arrangement for attaching to the vehicle. The pivotable support member is adapted to be pivoted between an attachment position, in which the attachment arrangement is exposed for attachment to the vehicle, and a concealed position. The present invention provides a connection device having an attachment arrangement. The attachment arrangement can be displaced so as not to interfere with objects, e.g., getting snared or caught.
US09821865B2 Compact pulling apparatus
The compact pulling apparatus includes a watertight elongated housing extending along a longitudinal axis and a track disposed around the housing along its longitudinal axis. The track enables the apparatus to move when rotatably driven around the housing. Depending on the implementation, the apparatus can include a generator/motor to selectively produce electricity which can power external equipment and rotatably drive the track, and/or a fuel-power engine. The apparatus further includes a power train assembly by which the rotating output power is transmitted from inside to outside the housing by the power train assembly using at least one rotatable shaft section sealingly extending across a corresponding one of the walls of the housing.
US09821863B2 Bluff body adaptive wake reduction system
A bluff body adaptive wake reduction system includes a series of fairings mounted to outer surfaces of the aft end of the road vehicle. The fairings are streamlined in geometry with an outer surface, a partially hollow core, and with a rear end surface curved such that left and right hand sides are convergent behind the vehicle. The fairings are coupled to at least one ram air inlet and also include at least one blown slot positioned on the rear end of the fairings enabling air flow to exit the fairings tangent to the rear end surface of the fairings. Air flow enters the system through the ram air inlets and exits through the blown slots. Air flow exiting the blown slots promotes flow traveling over the outer surface to remain attached to the outer surface and thus to the rear end surface. The rear end surface then deflects air flow to follow a convergent trajectory behind the vehicle in such a fashion as to reduce the size of the wake, and as a result reduce the aerodynamic drag.
US09821858B2 Al-plated steel sheet, method for hot-pressing Al-plated steel sheet, and automotive part
An Al-plated steel sheet includes: a steel sheet; an Al plating layer which is formed on one surface or both surfaces of the steel sheet and contains at least 85% or more of Al by mass %; and a surface coating layer which is laminated on the surface of the Al plating layer and contains ZnO and one or more lubricity improving compounds.
US09821857B2 Motor-vehicle floor panel structure
A motor-vehicle floor panel structure comprises a front body sub-unit, a central floor sub-unit, and a rear body sub-unit. The central floor sub-unit comprises a front floor structure including a central longitudinal tunnel, a pair of lateral longitudinal beams, connected to the front floor structure and to the front body sub-unit and two intermediate longitudinal beams which connect the central floor sub-unit to the front body sub-unit and which extend at intermediate areas between the lateral longitudinal beams and the central tunnel. The intermediate longitudinal beams are connected to the upper surface of the front floor structure and have portions which extend in a cantilever fashion from the front edge of the front floor structure and which are connected to said front body sub-unit. Due to this feature the floor structure has a lower surface which is substantially close to a regular continuous surface, so as to reduce turbulences in the air flowing under the floor panel structure during travel of the motor-vehicle, with a resulting positive impact on fuel consumption.
US09821856B1 Foldable mud flaps
A fully foldable mud flap has an upper flap section having a magnet permanently attached and a lower flap section having a magnet of the opposite polarity attached. The flap sections are connected by a hinge which allows rotation of the lower flap section in relation to the upper flap section, such that, in the retracted position, the lower flap section is parallel to and directly faces the upper flap section, with the magnets securing the flap sections in this position. The mud flap can be conveniently manually folded and unfolded, when desired.
US09821855B2 Motor vehicle body with filler piece
A motor vehicle body includes an A-pillar panel, an outer skin body panel, which together with an edge of the A-pillar panel delimits a gap. A windshield is adjacent to a longitudinal edge of the A-pillar panel. A filler piece has a first portion which fills out the gap and a second portion which conceals a gap between the longitudinal edge of the A-pillar panel and the windshield.
US09821852B2 Pressurized air insert for side impacts
A frame assembly for a vehicle includes a rocker elongated along an axis and defining a tubular cavity elongated along the axis. The vehicle frame assembly includes a sealed pressurized insert disposed in the cavity and elongated along the axis. The sealed pressurized insert increases the stiffness of the rocker, i.e., decreases the likelihood of deformation of the rocker during an impact of the vehicle, such as a side impact.
US09821847B2 Method for guiding an off-road vehicle along a curved path
As an off-road vehicle traverses a curved path driven by an operator, a data processor determines an error estimate between the points on the curved path and a generally circular perimeter about an estimated center point consistent with alignment of the curved path to the generally circular perimeter in accordance with a least squares algorithm or a modified least squares algorithm. The data processor or user interface provides an indicator to an operator of the vehicle that an arc length or angular displacement of the curved path with respect to the estimated center point is sufficient to estimate accurately the estimated center point and the radius of the generally circular perimeter if the determined error estimate is less than a threshold error.
US09821845B2 Trailer length estimation method using trailer yaw rate signal
A backup assist system for a vehicle reversing a trailer includes a trailer sensor module generating a trailer yaw rate and a vehicle sensor system generating a vehicle yaw rate and a vehicle speed. The system further includes a controller determining an estimated length of the trailer based on an estimated hitch angle, the vehicle yaw rate, the vehicle speed, and the trailer yaw rate in view of a kinematic relationship.
US09821844B2 Continuously variable speed transmission and steering differential
A continuously variable speed transmission and steering differential having a central drive axle, two pairs of sheaves and two shift arms. The drive axel is driven by an external power source. The two pairs of sheaves, left and right, are mounted to the drive axel. Each pair of sheaves includes a fixed drive sheave and a movable drive sheave. Each movable drive sheave is positioned by a shift arm. Shifting the shift arms left or right varies the gear ratio between the left and right pair of sheaves thereby providing steering control. Narrowing the distance between the shaft arms increases the gear ratio and consequently puts the transmission into a higher gear, thereby providing speed control.
US09821842B2 Rear wheel steering system and control method thereof
A rear wheel steering system may include: a vehicle speed detection unit configured to detect a vehicle speed; a steering angle detection unit configured to detect a steering angle based on an operation of a steering wheel; a pinion angle detection unit configured to detect a pinion angle based on an operation of the steering wheel; a rear wheel driving unit configured to steer rear wheels; and a control unit configured to receive the vehicle speed, the steering angle, and the pinion angle from the vehicle speed detection unit, the steering angle detection unit, and the pinion angle detection unit, calculate a target rear wheel steering angle for steering the rear wheels, calculate a final rear wheel steering angle at which a steering point of the rear wheels is adjusted using a steering angle speed, the vehicle speed, and the pinion speed, and operate the rear wheel driving unit.
US09821841B2 Dual bore integrated steering assist
The present invention provides a power assist steering system for a vehicle having a wheel. The steering system includes a first reciprocating member coupled to the wheel such that reciprocating movement of the first reciprocating member provides turning movement of the wheel, a steering input engaged with the first reciprocating member such that rotation of the steering input provides reciprocating movement of the first reciprocating member, and a steering assist assembly including a second reciprocating member engaged with the steering input such that reciprocating movement of the second reciprocating member provides an assist force to the steering input. Preferably, the first and second reciprocating members engage the steering input at locations opposed to each other and also move along paths that are substantially parallel to each other.
US09821840B2 Hydraulic control device and construction machinery including same
A hydraulic control device includes: a hydraulic pump connected in parallel to steering and boom cylinders; a steering control valve that controls the direction of operating oil flowing through the steering cylinders; a boom control valve that connects the hydraulic pump to a tank when the valve is at a neutral position and controls the direction of the oil flowing through the boom cylinders when the valve is at an offset position; a meter-in pressure compensator that increases flow rate of the oil flowing through a variable restrictor of the steering control valve in accordance with pressure in front of and behind the restrictor; and a bleed-off pressure compensator that decreases flow rate of the oil flowing through the boom control valve in accordance with the increase in pressure of the oil flowing through the steering cylinders to maintain the predetermined pressure of the oil in the steering control circuit.
US09821829B1 Bottom dumping wheelbarrow
A bottom dumping wheelbarrow including a wheelbarrow having a support frame, an upper member disposed atop the support frame, a pair of handles attached to the support frame, and a plurality of wheels attached to and downwardly extended from the support frame. A door is disposed within a bottom side of the upper member. A control handle is pivotally attached to a bottom surface of the support frame of the wheelbarrow and affixed to the door. The door has an open position and an alternate closed position.
US09821827B2 Collapsible wheeled support or carrier
A laterally collapsible, user-pushed, four-wheeled rollator, stroller or the like has swiveling front wheels for steering, each mounted in a fork with a vertical post, with a toothed pulley fixed thereto, rotatable in a bearing housing fixed at the front end of right and left side frames. The two swiveling front wheels can swivel to any steering angle but always in unison with each other by virtue of a flexible toothed synchronous belt extending between the toothed pulleys. The interior of each bearing housing closely surrounds each toothed pulley and the belt, preventing any disengagement of the belt from either toothed pulley even when the belt becomes slack when the left and right side frames are folded towards each other. A synchronous chain with sprockets can also be used. Tether means pull the belt/chain rearwardly to a protected position during folding.
US09821825B2 Apparatus and method for processing ATC intermittent information in railway
The present invention relates to an apparatus and method for processing an intermittent information in railway, the method comprising determining that data of a prescribed first length is received in first and second buffers; reading and storing the data of the first length in the first and second buffers; determining that data of a prescribed second length is received in the first and second buffers; reading and storing the data of the second length in the first and second buffers; and generating a final data by combining the data of the first length and the data of the second length.
US09821823B2 Track circuit power supply vital monitor
A power supply vital monitor for track circuits for railway systems includes a track segment that is separated from adjacent segments by electric joints. Each track segment includes a signal transmitting unit and receiving units for transmitting and receiving train presence detection signals and/or transmitting or receiving communication signals between the train and the track segment. The transmitting unit and receiving units are connected to a common power supply line. To avoid an erroneous clearing of an occupied status caused by spurious signals on the power supply line affecting reception of the train detection signals, each receiving unit includes a first and a second channel, which connect the receiver with the corresponding track circuit and with a power supply sensor connected to the power supply line. Switches enable and disable connections of the receivers to the corresponding track circuit and to the corresponding power supply sensor.
US09821821B2 Measuring device
A measuring device is applied to an active damping system, the active damping system including a damper having a plurality of sensors and a plurality of actuators, the damper being arranged on an object to be subjected to damping. The measuring device includes: a transmission characteristic storage unit configured to store a plurality of transmission characteristics calculated from driving signals and vibration state signals; a damping performance setting unit configured to set damping performance including the amount of vibration reduction required of the active damping system and a frequency of vibration; and a damper configuration calculator configured to calculate how many the number of the sensors and actuators for the damper is increased or decreased on the basis of the transmission characteristics and the damping performance, with the increase or decrease being necessary in order that the damping performance set in the damping performance setting unit is satisfied.
US09821819B2 Auxiliary power unit assembly and method of use
A locomotive assembly including an auxiliary power unit and a method of providing auxiliary power to a locomotive are disclosed. The locomotive assembly includes a locomotive having a power bus, a primary power source electrically coupled to the power bus, and a locomotive controller programmed to control the primary power source and transmit a first command signal to a power unit that is electrically coupled to the power bus. The power unit includes an auxiliary engine-generator set, a power interface electrically coupling the auxiliary engine-generate set to the power bus, and an auxiliary controller electrically coupled to the locomotive controller. The auxiliary controller is programmed to receive the command signal from the locomotive controller indicating a desired amount of power, control the auxiliary engine-generator set to produce at least the desired amount of power, and control the power interface to deliver the desired amount of power to the power bus.
US09821818B2 Engaging and disengaging for autonomous driving
Aspects of the present disclosure relate switching between autonomous and manual driving modes. In order to do so, the vehicle's computer may conduct a series of environmental, system, and driver checks to identify certain conditions. The computer may correct some of these conditions and also provide a driver with a checklist of tasks for completion. Once the tasks have been completed and the conditions are changed, the computer may allow the driver to switch from the manual to the autonomous driving mode. The computer may also make a determination, under certain conditions, that it would be detrimental to the driver's safety or comfort to make a switch from the autonomous driving mode to the manual driving mode.
US09821816B2 Control method for driving of vehicle for fail-safe
A control method for driving of a vehicle for fail-safe, including: determining, by a controller, whether an interface apparatus selecting a shift range fails; confirming, by the controller, the shift range selected upon the failure determination; determining whether the vehicle is in a parking state when the shift range selected upon the failure determination is out of a D range; as a result of performing the determining of the parking, when the vehicle is in the parking state, guiding, by the controller, a driver to step on an accelerator pedal for forward driving of the vehicle; and after the guiding of the driving, when a manipulated quantity of an accelerator pedal is detected, limiting, by the controller, a torque to reduce an output torque value of the vehicle depending on the manipulated quantity of the accelerator pedal for a predetermined reference time.
US09821814B2 Device and method for determining drowsiness and non-transitory storage medium
A drowsiness determination device includes an input unit that receives vehicle information indicating the amount of variation in an attitude of a vehicle with respect to a road surface and head information indicating the amount of movement of a head of an occupant with respect to a predetermined position and a determination unit that determines whether the occupant is drowsy, on the basis of the vehicle information and the head information. The determination unit determines that the occupant is drowsy, on the conditions that when the vehicle attitude varies, the occupant head moves in the same direction as the direction in which the vehicle attitude has varied and that a delay time between the timing when the vehicle attitude has varied and the timing when the occupant head has moved is longer than a predetermined time.
US09821813B2 Continuous occlusion models for road scene understanding
Systems and methods are disclosed for road scene understanding of vehicles in traffic by capturing images of traffic with a camera coupled to a vehicle; generating a continuous model of occlusions with a continuous occlusion mode for traffic participants to enhance point track association accuracy without distinguishing between moving and static objects; applying the continuous occlusion model to handle visibility constraints in object tracks; and combining point track association and soft object track modeling to improve 3D localization accuracy.
US09821808B1 Autonomous boat launching
A computing device for a vehicle includes a processor and a memory. The processor is programmed to determine that a vehicle destination includes a boat launch and that the vehicle is towing a trailer including a boat. The computing device guides the vehicle at the boat launch to position the trailer to launch the boat.
US09821806B2 Control apparatus for vehicle
When neutral control is started by placing a CVT drive clutch in a semi-engaged state while a vehicle is decelerating in a state where a second power transmission path is established, a clutch mechanism that is semi-engaged in neutral control while the vehicle is decelerating is changed from the CVT drive clutch to a forward clutch before a stop of the vehicle, so it is possible to continue the neutral control until a stop of the vehicle. At a stop of the vehicle, a power transmission path is already changed to a first power transmission path that establishes a gear ratio (EL) higher than a highest gear ratio (γmax) that can be established by the second power transmission path. Thus, right after a stop of the vehicle, it is possible to execute idle stop control.
US09821805B2 Vehicle control device
A vehicle control device includes a controller configured to perform: ignition starting of an engine when a detected crank angle is within a first area in which the ignition starting of the engine may be performed with probability not smaller than a first predetermined value; and the ignition starting of the engine while increasing an engine speed by engaging a clutch to transmit torque of a drive wheel to a crankshaft when the crank angle is within a second area in which the ignition starting of the engine may be performed with probability not smaller than a second predetermined value smaller than the first predetermined value and smaller than the first predetermined value, the instruction is output based on a signal indicating that a braking unit is turned on, and a gear of a transmission is not in neutral.
US09821804B2 Enhanced vehicle speed control
A demand is identified based on input from a vehicle operator. Data is received providing a history of vehicle velocities. An estimated reference velocity is generated based at least on the velocity data. A final demand is generated based at least in part on a reference velocity indicated by the velocity control signal and the estimated reference velocity.
US09821800B2 Processor for a vehicle
A processor for a vehicle includes a vehicle yaw moment instruction calculator, and a mode under which yaw moment of the vehicle is controlled. If the vehicle yaw moment instruction value generates the driving forces or the driving torques, the driving forces or driving torques are different between the left and right wheels. If the vehicle yaw moment instruction value generates the braking forces or the braking torques, the braking forces or the braking torques are different between the left and right wheels. The mode operates at least in transit region between daily region and limit region.
US09821799B2 Vehicle pump condition response method and assembly
An exemplary pump condition response method includes, in response to a pump condition, operating an engine to discontinue or prevent a first stop-start cycle during a drive cycle. The method permitting a second stop-start cycle during the drive cycle.
US09821796B2 Hybrid vehicle
When reproduction of a filter is required, and a filter temperature is within a first temperature range, an ECU executes a control process including the steps of executing a successive motoring control, determining an intermittent motoring period, an intermittent stopping period, and an intermittence number when the filter temperature is within a second temperature range, and executing an intermittent motoring control.
US09821791B2 Hybrid vehicle controller and method of controlling a hybrid vehicle
The invention relates to a controller (140) for a hybrid electric vehicle (HEV), the controller (140) being operable to control a HEV to assume a HEV mode of operation in which each of a plurality of actuators (121, 123) of a HEV is controlled to assume a prescribed operational state, the controller being configured to control a HEV to assume an operational mode responsive to data in respect of a route of a journey to be made by a HEV, a route comprising at least one route segment, the controller (140) being configured to determine a target state of charge of an energy storage device (150) of a HEV for each said at least one route segment being a state of charge of an energy storage device (150) that is to be achieved at the end of said at least one segment responsive to the data in respect of a route, the controller (140) being further configured to control the HEV to achieve the target state of charge at the end of said at least one segment.
US09821789B2 Vehicle drive and method with electromechanical variable transmission
A vehicle drive includes a gear set, a first motor/generator coupled to a sun gear of the gear set, a second motor/generator selectively coupled to at least one of (a) a planetary gear carrier of the gear set and (b) a ring gear of the gear set, an engine coupled to the ring gear of the gear set and selectively coupled to the second motor/generator, and a clutch configured to selectively engage the second motor/generator to the engine. The first motor/generator and the second motor/generator are electrically coupled without an energy storage device configured to at least one of (a) provide electrical energy to the first motor/generator or the second motor/generator to power the first motor/generator or the second motor/generator and (b) be charged by electrical energy from the first motor/generator or the second motor/generator.
US09821788B2 Method for reducing drag torque fluctuations upon electric drive-off
A method is described for operating a motor vehicle, in which control is applied, in the context of a drive-off operation, to an electrical machine operable in motor mode in order to deliver a torque driving the vehicle, control simultaneously being applied to a braking system of the motor vehicle in such a way that it applies a braking torque.
US09821787B2 Circuit board and vehicle brake hydraulic pressure control unit
One embodiment provides a circuit board having a substrate and an electrode portion which is provided on the substrate. The electrode portion includes: a quadrangular land which is provided on a front surface of the substrate; a solder layer which is laminated on the whole of a front surface of the land; and a pad which is joined to a front surface of the solder layer. When the electrode portion is seen from thereabove, an outer circumferential line of the pad touches each of four sides of the land. Exposed portions where the solder layer is exposed are formed individually at four corners of a front surface of the electrode portion. And, the exposed portions are formed to have the same shape.
US09821782B2 Motor pump
A motor pump includes a base body, a pump, and a motor. The motor includes a tubular yoke having a bottom and an opening on a base body side, a bearing, a rotation shaft, a rotor, a commutator, a brush and a brush shaft. The bearing is fitted to an inside of a bearing hole of the base body. The brush holder is fitted to an inside of the yoke and engages with an outer peripheral surface of the bearing. The brush holder and the bearing are disposed so as to be spaced from the base body in an axial direction of the rotation shaft. The motor-side seal member is provided between the yoke and the base body. The base body constitutes a stopper that prevents the brush holder from being extracted from the yoke.
US09821776B2 Brake actuation sensor device for a vehicle brake system and method for mounting a brake actuation sensor device on a vehicle brake system
A brake actuation sensor device is described for a brake system of a vehicle having a strain and/or compression gage which is reversibly variable in its extension, whereby at least one electrical property is able to be changed, and an evaluation device, by which at least one electrical variable is able to be ascertained with respect to the changeable electrical property, and, taking into account the at least one ascertained electrical variable, an evaluation variable is able to be determined with respect to a brake actuating force, the strain and/or compression gage being additionally developed so that the strain and/or compression gage is able to be situated in direct or indirect contact with a brake booster housing device in such a way that a force exerted on the brake booster housing device causes a mechanical stress in the strain and/or compression gage. Furthermore, a method is described for mounting a brake actuation sensor device of a brake system of a vehicle.
US09821775B2 Vehicle transmissions having a park function
In response to driver selection of PARK, a vehicle transmission is commanded to momentarily select and hold NEUTRAL before PARK, while a vehicle wheel brake is applied. Such an arrangement avoids trapping torque in the driveline, and thus can obviate pawl ‘thump’ when PARK is next disengaged.
US09821774B1 Method and apparatus for jackscrew with integral drive nut grease fitting
An improved device and method of lubrication for a tongue jack, 5th wheel jack, or other jack or other threaded positioning device. Ports are provided in the inner and outer tubes of the jack. The aligned ports provide access to a lubrication cavity in the jacknut. The lubrication cavity may include a grease fitting such as a zerk fitting. When the ports are in alignment, a grease gun can be inserted easily to the zerk fitting to apply grease to the interior structure of the nut as well as to the threads of the jackscrew. The lubricant may be introduced directly at a region of contact between a screw and the load bearing element. Applicant's test results show that this improved lubrication can increase the life cycle of the jack by more than 100%.
US09821772B2 Windscreen wiper device
A windscreen wiper device comprising an elastic, elongated carrier element, as well as an elongated wiper blade of a flexible material, which can be placed in abutment with a windscreen to be wiped, which wiper blade includes at least one longitudinal groove, in which groove a longitudinal strip of the carrier element is disposed, which windscreen wiper device comprises a connecting device for an oscillating wiper arm, as well as a spoiler, characterized in that the spoiler is movable from a first position, wherein the spoiler has an symmetric profile, seen in cross-section of the wiper blade, in the absence of a wind load thereon, into a second position, wherein the spoiler has a asymmetric profile, seen in cross-section of the wiper blade, in the presence of a wind load thereon.
US09821770B2 Windowpane defogging device for a motor vehicle and windowpane defogging method using the same
The present invention provides a windowpane defogging device for a motor vehicle which, upon generation of a fog on a windowpane, comes into a defogging mode to remove the fog generated on the windowpane. The windowpane defogging device includes a relative humidity detecting unit configured to detect a windowpane relative humidity of a driver seat view field region of the windowpane and a windowpane relative humidity of a passenger seat view field region of the windowpane, and a control unit configured to control entry into the defogging mode by determining the generation or non-generation of the fog on the windowpane based on the windowpane relative humidity of the driver seat view field region and the windowpane relative humidity of the passenger seat view field region inputted from the relative humidity detecting unit.
US09821768B2 Geo-proximity vehicle alert and access system for security and package exchange efficiency
A geo-proximity Vehicle Alert and Access System (VAAS) is discussed that has a cloud based server having a GPS-based proximity system to control and track a package exchange process, to speed up a package delivery and pick-up process, and to ensure security for the package exchange process. The cloud based server is configured to receive both current GPS coordinates of a package carrier's vehicle and current GPS coordinates of a target vehicle for at least one of package delivery to the target vehicle and package pick up from the target vehicle. The cloud based server is configured to send to the target vehicle the commands to wake-up an on-board telematics module, to give an alert, to unlock the target vehicle, and to lock the target vehicle after receiving a confirmation of the package exchange process.
US09821766B2 System and method for anti-theft and tracking of an automobile and automobile wheels
The present invention provides a system and method for anti-theft and tracking of automobile and automobile wheels. The system comprises of an alert and tracking device (105) installed on the inside of an air stem of a wheel along with tire pressure monitor system (TPMS), wherein the alert and tracking device (105) detects and alerts of theft when there is an unauthorized movement such as lifting, tampering, removal of the wheel and also tracks and monitors the position of the stolen wheel. The system further comprises of a remote tracking application (111) to control and track the stolen wheel from the remote location.
US09821764B2 Smart entry system
A smart entry system includes a smart control unit that detects whether communication with a portable device has been established, and a centralized control unit that unlocks a driver's door when a driver's door unlock operation is detected and establishment of communication with the portable device is detected. The centralized control unit includes a timer unit that measures time when a passenger's door open operation is detected or when a passenger's door open operation is detected and the fact that communication with the portable device has not been established is detected. The centralized control unit unlocks at least one of the passengers' doors along with the driver's door when a driver's door unlock operation is detected and establishment of communication with the portable device is detected while the timer unit is measuring a certain period of time.
US09821760B2 Locking device, vehicle seat belt adjusting device, and vehicle seat belt
A locking apparatus used for controlling a movable chain, strip or strap-shaped object (71) comprising a support frame; a roll shaft (6) with a friction surface or a sprocket pitch slot (64), the roll shaft (6) being fixedly connected to a support rod (66), and one end of the support rod (66) being pivotally connected onto the support frame; a pawl (62) disposed above the roll shaft (6) and capable of rotating around one end; and a pressurization body (3) opposite to the roll shaft (6) along a transverse direction, thereby forming a roll gap between the roll shaft (6) and the pressurization body (3). The roll shaft (6) can freely rotate when the roll shaft (6) is in a middle state. When the roll shaft (6) is forced to downwards pivot until a ratchet disposed on a contact base (65) engages with a ratchet (6302) of the roll shaft (6) to prevent the rotation of the roll shaft (6), the object (71) can be locked. When the roll shaft (6) is forced upwards pivot until the ratchet (6302) of the roll shaft (6) abuts against the pawl (62), the roll shaft (6) can still rotate; when the object (71) changes the direction to downwards move, the pawl (62) engages with the ratchet (6302) of the roll shaft (6) to prevent the rotation of the roll shaft (6) and loses the engagement with the ratchet (6302) of the roll shaft (6) as the roll shaft (6) downwards pivots.
US09821758B2 Pretensioning, force-limiting seat belt assembly
A seat belt assembly for a vehicle includes a pretensioner, and a cable connected to the pretensioner. The seat belt assembly includes a torsion bar having a plurality of teeth. The cable has slots interlocking with the teeth. During a sensed impact of the vehicle, the pretensioner is activated to retract the cable to pretension the seat belt assembly relative to an occupant of the vehicle. The interlocking of the slots with the teeth exerts torsional forces on the torsion bar, which yields to reduce forces on a chest of the occupant.
US09821748B2 Vehicle interior panel and vehicle airbag device
An instrument panel of an automobile includes a base and a covering bonded to a surface of the base. A cleavage groove is formed on the back of the base. When the base is cleaved by inflation pressure of an airbag, the cleavage groove serves as a starting point of the cleavage. The covering is formed by a ground fabric layer made of knitted fabric and a covering layer bonded the surface of the ground fabric layer. The ground fabric layer is formed of an original fabric in which the tensile strength in directions along its surface is anisotropic. The cleavage groove includes a first groove section, which is cleaved first. The covering is oriented with respect to the base such that the direction of the smallest tensile strength of the ground fabric layer matches with a direction perpendicular to the direction in which the first groove section extends.
US09821739B2 Automobile bumper
An automobile bumper is provided in which the bumper beam includes a middle curved part that curves concavely rearwards and a pair of left and right curved parts that curve convexly rearwards, and the left and right curved parts includes a rear side frame connecting part and a load input part projecting rearwards the most among the bumper beam parts. Since the bumper beam includes a compression-resistant reinforcing part provided along the inner face in the fore-and-aft direction of the load input part, and an extension line of the compression-resistant reinforcing part is directed toward the vicinity of the load input point of the load input part, supporting the compressive load by the compression-resistant reinforcing part to thus prevent the bumper beam from being destroyed enables the strength toward bending deformation to be enhanced without reinforcement by increasing the plate thickness of the bumper beam.
US09821737B2 Isolation of auxiliary electronics battery from starting battery
A battery combiner may be used to electrically isolate first and second batteries during conditions in which a first battery required for a mechanical drive system may experience excessive power draw. The second battery may be used to provide a switched and/or continuous power source to a control system and/or other electrical devices for reliable operation, and the combiner may join the first and second batteries together such that both are electrically charged by a single alternator during conditions when it is safe.
US09821734B2 Concealed embedded circuitry, vehicles comprising the same, and related methods
Electronic circuitry for mounting on articles, such as vehicles, is concealed by embedding the circuitry using at least an overlying polymeric material within a concealed embedded circuitry structure. The concealed embedded circuitry is capable of ready and effective application to an article and is capable of being retrofitted to articles after their fabrication.
US09821731B2 Composite floor and motor vehicle comprising such a floor
The invention relates to a motor vehicle floor having a lower floor made from a composite material; and an upper floor made from a composite material, extending opposite at least part of the lower floor, the lower and upper floors being connected to one another. The floor includes at least one cavity at least partially delimited by the lower or upper floor and communicating with the exhaust line of the motor vehicle.
US09821724B2 Mounting apparatus for portable electronic device
Described herein is a mounting apparatus, comprising a magnetic component, and a mount; wherein the magnetic component comprises one or more permanent magnet; wherein the mounting apparatus is configured to attach to a surface through a magnetic interaction between the magnetic component and a material that is ferromagnetic or ferromagnetic in the surface; wherein the mount comprises a plurality of clips which are configured to be mounted on an air vent in a vehicle. The mounting apparatus provides mounting of any appropriately sized electronic device in a vehicle, to allow convenient viewing and access to the device. The presently disclosed mounting apparatus also realizes a continuous rotation and continuous movement of the portable electronic device while it is held by the mounting apparatus, therefore facilitating user control of the device.
US09821717B1 Box step with release button that illuminates
A step assembly of a vehicle is provided herein. The step assembly includes a box step having a release button that luminesces in response to excitation light and continues to luminesce for a period of time after the excitation light cease to be provided. A drive mechanism is configured to move the step pad from a stowed position to a deployed position when the release button is pressed.
US09821714B2 Light assembly
A light assembly for a school bus. The light assembly includes a housing having a front side and a rear side, wherein the rear side is mountable to a school bus. The front side of the housing includes a perimeter light, a stop light, and a platform light, wherein the lights can alert vehicles approaching a stopping school bus. The perimeter light is disposed around a perimeter of the housing and can produce an amber color. The stop light includes the word ‘stop’ in a non-colored transparent material and the platform light, disposed between the perimeter light and the stop light, can produce a red color. In one embodiment, the light assembly is operably connected to a control, speedometer, and door assembly of a school bus, allowing the light assembly to automatically activate when the school bus stops and automatically deactivate when the school bus door closes.
US09821711B2 Lighting system, in particular for a motor vehicle lighting member, comprising a light-emitting element offset from the light source
A lighting system for a motor vehicle includes a printed circuit board equipped with light emitting diodes for emitting light beams in lighting directions and an optical module formed to propagate and transmit the light beams. The optical module has a reception surface to receive the light beams and an emission surface for retransmitting the light beams. The lighting system also includes at least one element for masking the light beams emitted by the light emitting diodes. The element for masking which extends from at least one of the light emitting diodes toward the reception surface and substantially parallel to the lighting direction of the at least one light emitting diode, over at least a part of the periphery of the at least one light emitting diode and over at least a part of a distance separating the at least one light emitting diode and the reception surface.
US09821708B2 Illuminated exterior strip
A lighting system for a vehicle panel is provided herein. The lighting system includes an outer panel mated to an inner panel. An aperture is disposed in the outer panel. A light-producing assembly is arranged as a strip and includes a plurality of light sources. A photoluminescent structure is configured to luminesce in response to excitation by the plurality of light sources. A retention feature is coupled to the light-producing assembly and insertable through the aperture for disposing the light-producing assembly on the outer panel.
US09821705B2 Lighting device carrying out multiple lighting functions of an automotive vehicle using functionally dedicated light source groups
A lighting device for an automotive vehicle comprising means for controlling the supply of power to a plurality of light sources, the plurality of sources being divided into at least two groups of sources. The device according to the invention is remarkable in that each of the light source groups fulfills a specific lighting function of the device and is distinguished by a requirement for electric current of a specific intensity. Additionally, the control means are capable of selectively supplying power to each of the light source groups exclusively of the other groups. A power supply method implementing the device according to the invention is also proposed.
US09821703B2 Steering wheel light bar
The present invention is directed to a steering apparatus for a vehicle having a including a light element providing indication and warning light signals to the user of the vehicle. The light element can be associated with a PCB mounted to the steering wheel grip for controlling the operation of the light element.
US09821702B2 Warning light assembly
A warning light for attachment to a vehicle comprising a thermally conductive longitudinally extending base, a plurality of light head mount assemblies, a plurality of LED warning light assemblies, and a plurality of electronic control circuits. Said base has a pair of generally parallel longitudinal edges and a pair of ribs projecting perpendicularly from said base. Said light head mount assemblies comprise a bracket and a light head retention shoe. Said bracket has a generally planar bracket first portion and a generally planar bracket second portion oriented perpendicular to said first portion. Said light head shoe has a sole configured to engage said bracket first portion, a rib engaging portion, and a brace extending angularly therebetween. Said LED assemblies are mounted on said bracket second portion. Said dome has a main body portion, sidewalls configured to engage said edges, and end walls.
US09821701B2 Cargo restraint assembly
An assembly for engaging an elongated support for restraining cargo in a container having corrugated or flat walls. The assembly comprises a cargo restraint device having a sleeve member having a base and defining a cavity for receiving an end of the elongated support. The base having a securing surface facing opposite the cavity for securing the sleeve member to the wall. The assembly also includes a bracket engageable with the sleeve member having a securing surface for securing the bracket to the wall adjacent the cargo restraint device.
US09821697B2 Inflatable cushion disposed between front and rear seats of a vehicle
A vehicle includes a floor, a rear seat, and a front seat rotatable relative to the rear seat from a first position facing the rear seat to a second position facing away from the rear seat. An inflatable cushion is supported by the floor and is disposed between the front seat and the rear seat. A pressure control device is in communication with the inflatable cushion. The inflatable cushion may be used by an occupant of the vehicle as a footrest and/or a bed.
US09821696B1 Integrated assist handle
A door assembly includes a door frame, which generally defines a door opening. An assist handle is movably attached to the door frame. The assist handle is movable between a retracted position, proximal to the door frame, and a deployed position, distal from the door frame.
US09821695B2 Vehicle seat
A vehicle seat includes: a seat shell; a seat pad disposed on a support surface of the seat shell, the support surface being configured to support a seated occupant; an airbag device held at an outer side of a side portion of the seat shell in its width direction, the airbag device being configured to be deployable on the side of the seated occupant; and a seat cover held taut on the outside of the seat pad. The seat cover covers an outer peripheral surface of the seat pad and an outer peripheral surface of the airbag device. The seat cover comes around behind a rear surface of the seat shell and the seat cover is engaged with the rear surface of the seat shell. The rear surface is on the opposite side of the seat shell from the support surface.
US09821692B2 Deployable leg rest assembly
A deployable leg rest assembly (3) for mounting to a seat pan (9) of a vehicle seat frame (11) comprises a leg support (4), a mounting plate (13) and a deployment mechanism (6) for deploying the leg support (4). The deployment mechanism (6) connects the leg support (4) to the mounting plate (13). The mounting plate (13) is adapted to be located above the seat pan (9). The deployable leg rest assembly (3) can be mounted to different vehicle seats (1) by accessing the seat pans (9) of the corresponding vehicle seat frames (11).
US09821691B2 Ratcheting armrest assembly for a vehicle
A ratcheting armrest assembly includes an articulating frame assembly. Also included is a ratchet anchor operatively coupled to the articulating frame assembly for rotation with the articulating frame assembly. Further included is an anchor assembly operatively coupled to the articulating frame assembly. Yet further included is a ratchet operatively coupled to the anchor assembly. The ratchet includes a first plurality of teeth and the ratchet anchor including a second plurality of teeth, wherein the first plurality of teeth and the second plurality of teeth are engageable with each other, the second plurality of teeth free to rotate relative to the first plurality of teeth in a first rotational direction and self-locking with the first plurality of teeth in a second rotational direction. Also included is a directional spring biasing the ratchet in the second direction in a first orientation and in the first direction in a second orientation.
US09821688B2 Rear seat cushion with H-point articulation
A vehicle seat assembly includes a fixed mounting plate and a support bar coupled with the mounting plate and slidable with respect thereto along an arcuate path. A cushion support is coupled with the support bar, and a drive mechanism is operably coupled with the cushion support to rotate the cushion support about a center of the arcuate path positioned opposite the rail by sliding of the support bar along the path.
US09821687B2 Seat system for a vehicle
A seat system (1) for a vehicle, includes a plurality of seats (2.1 to 2.3) which are disposed next to one another and at least two of which are pivotable about a common pivot axis (S). At least one of the seats (2.2) that are pivotable about the common pivot axis (S) is designed in such a way that when the seat is unlocked and the backrest thereof is pivoted by more than a predefined angle of inclination, the adjacent other seat (2.1) is blocked in the unlocked state or at least the folding movement of the backrest thereof is dampened or prevented.
US09821683B2 Easy seat positioning and installation
A seat mounting apparatus of a vehicle, including a plurality of seat tracks mounted in the vehicle; a plurality of seat sliders at least equal in number to a number of the plurality of seat tracks, each of the plurality of seat sliders being slidable along one of the plurality of seat tracks; and a seat mounting bracket that aligns and fixes a relative position in the direction of a number of the plurality of seat sliders equal to the number of the plurality of seat tracks.
US09821678B2 Battery enclosure having T-shaped guides on the outer surface for stiffeners and impact absorbing elements
A battery housing for a traction motor battery of a vehicle is disclosed that includes attachments retained by parallel T-shaped guides on the outer surface of the walls of the enclosure. The attachments are oriented to extend either in a horizontal orientation or vertical orientation. The depth of the attachments and shape of the attachments may be selected to meet impact force requirements and packaging space limitations imposed by the structure of the vehicle.
US09821676B2 Electric vehicle charging apparatus having a welding monitoring relay that is opened and closed during charging operations
A charging device includes: a plurality of main relays forming a connection between an electric vehicle (EV)-side connector and an outlet-side connector; a relay welding sensing unit connected to the plurality of relays to sense the presence or absence of welding of the plurality of relays; a welding monitoring relay opening and closing between the relay welding sensing unit side node and a main relay side node; and a control unit controlling the open and close of the welding monitoring relay.
US09821674B2 Method, device and system for determining a position of a vehicle
The invention relates to a method, to a device, and to a system for determining a position of a vehicle. The method comprises the method steps: Measuring (S01) at least one first magnetic field strength of a magnetic field at one each first position (A-i) by means of a first magnetic field sensor (11) arranged on a vehicle (1); measuring (S02) at least one second magnetic field strength of the magnetic field at one each second position (B-i) by means of a second magnetic field sensor (12) arranged on the vehicle (1) at a distance from the first magnetic field sensor (11); determining (S03) position data of the vehicle (1) at least by comparing data, which are based on the measured first and second magnetic field strengths, to a predetermined magnetic field data of the magnetic field; and outputting (S04) a signal based on said position data.
US09821671B2 Wall plug system for electric vehicle
An electric vehicle charging system in described that includes an electrical energy source that includes a base with a plurality of electrical signal connectors to receive a first electrical signal, a second electrical signal and a ground signal, an adapter having a plurality of outlet connectors configured to electrically connect to at least some of the plurality of electrical signal connectors, wherein the adapter can be placed in a plurality of positions on the base to correctly orient the base to any of plurality of outlet connector orientations, and a locking ring adapted to engage the base to removable fix the adapter to the base in one of the four positions. The system can include a thermistor assembly to sense thermal energy in the source and if thermal energy exceeds a threshold to output a signal. The system can include a charging cord for an electric vehicle having a proper orientation when engaging the source, wherein the adapter is in a correct orientation with the base being in the proper orientation when connected to the socket-outlet.
US09821669B2 Electric vehicular connector and vehicular power supply device
The electric vehicular connector includes: a connection terminal block including a primary power transmission terminal to be electrically connected to a first power terminal of a power converter; a plug including a secondary power transmission terminal to be electrically connected to a second power terminal of an inlet of an electric vehicle; a breaker which is connected between the primary power transmission terminal and the secondary power transmission terminal and has a closed state of electrically interconnecting the primary power transmission terminal and the secondary power transmission terminal and an open state of electrically separating the primary power transmission terminal and the secondary power transmission terminal from each other; and a breaker controller configured to set the connector-side breaker in the closed state during a normal state and to set the connector-side breaker in the open state during an abnormal state in which abnormality occurs in the electric vehicle.
US09821668B2 Method and apparatus for charging multiple energy storage devices
An electric vehicle includes a controller configured to receive sensor feedback from a high voltage storage device and from a low voltage storage device, compare the sensor feedback to operating limits of the respective high and low voltage storage device, determine, based on the comparison a total charging current to the high voltage storage device and to the low voltage storage device and a power split factor of the total charging current to the high voltage device and to the low voltage device, and regulate the total power to the low voltage storage device and the high voltage storage device based on the determination.
US09821664B2 System and method for emergency starting of fuel cell vehicle
A system and method for emergency starting of a fuel cell vehicle is provided. In particular, a high-voltage converter, a balance of power (BOP), and a controller are included in the system. The high-voltage converter is configured such that one side thereof is connected to a high-voltage battery via a battery switch and the other side thereof is connected in parallel to a plurality of fuel cells. The BOP is connected in parallel to the high-voltage converter and the fuel cells. The controller is configured to control the power supplied from the high-voltage battery to the BOP without conversion by connecting the battery switch upon the failure of the high-voltage converter or high-voltage battery.
US09821663B2 Systems and methods for battery regeneration based on engine loading
An alternator voltage may be controlled based on a proportional gain scheduling in response to an engine load of an internal combustion engine and/or a state of charge (SOC) deviation for a battery based on a target SOC of the battery and an actual SOC of the battery. The alternator voltage may be a voltage less than a current battery voltage under high engine loads to enable the battery to power an accessory system and the alternator voltage may be a voltage greater than a voltage of the battery under low engine loads or engine loads less than high engine loads to enable the alternator to charge the battery.
US09821662B2 Braking force control system, vehicle and method of controlling braking force
A braking force (BF) control system includes: a first required BF calculator that calculates, based on a position of the brake pedal, a first required friction BF allocated to the friction brake and a first required regenerative BF allocated to regenerative control of the drive motor; a second required BF calculator that calculates, based on a position of the acceleration pedal, a second required friction BF allocated to the friction brake and a second required regenerative BF allocated to the regenerative control; a regenerative total BF calculation/execution portion that calculates a regenerative total BF based on the first and second required regenerative BFs and performs the regenerative control based on the regenerative total BF; and a friction total BF calculation/execution portion that calculates a friction total BF based on the first and second required friction BFs and controls the friction brake based on the friction total BF.
US09821661B2 Device and method for operating an electric machine
The invention results in improved switching from the idling mode to an active short circuit mode of an electric machine. According to the invention, the switch from the idling mode to the active electric short circuit mode is delayed until predefined voltage conditions have been reached on the external terminals of an electric machine or until the rotor of the electric machine is in a predetermined position corresponding to the required voltage conditions.
US09821660B2 Display system
A display system equipped to a vehicle includes a display screen, a notification section, a determination section, and a display control section. The display screen displays information for a vehicle occupant. The notification section preliminarily notifies the vehicle occupant of an information update to be performed on the display screen. The determination section determines whether the vehicle occupant pays attention to the display screen after the notification section notifies of the information update. The display control section performs the information update in order to display new information on the display screen when the determination section determines that the vehicle occupant pays attention to the display screen.
US09821659B2 Ultrasonic wading detection for a vehicle
A wading sensor for a vehicle comprises an ultrasonic parking distance control. An embodiment detects wading by sensing the difference in the settling time of the diaphragm of a transmitter/receiver, in water and in air. Other embodiments are disclosed.
US09821658B1 Method for controlling vehicle creep driving
A method for controlling vehicle creep driving includes learning, by a controller, a touch point of a clutch when a condition for creep driving is satisfied, changing, by the controller, an upper limit of a creep clutch torque, which is set as a permissible maximum torque of the clutch during creep driving, depending on the learned touch point, and controlling, by the controller, creep driving such that the creep clutch torque required for creep driving is set to be equal to or less than the changed upper limit of the creep clutch torque, and the creep clutch torque is output.
US09821656B2 Blower drive system for a vacuum truck
A blower drive system for a vehicle such as a vacuum truck includes a blower including a blower input shaft and a blower housing; a transfer case operably connected to transfer drive from the vehicle engine driveline to the blower input shaft; a frame bracket assembly including one or more connections to the vehicle chassis frame and one or more connections to the blower housing. The frame bracket assembly mounts the blower housing in a specified fixed angle with respect to ground and mounts the bottom of the blower housing in a specified fixed height above the vehicle chassis frame.
US09821654B2 Transverse dual planetary system
A final drive unit for a motor vehicle includes a sprocket driven by a transmission, a first planetary gear set where one of the rotational members is connected to the sprocket, a second planetary gear set where one of the rotational members is connected to the first planetary gear set, and an actuator moveable between a low range position and a high range position. The actuator is rotationally coupled to a differential. When the actuator is in the low range position, the actuator rotationally couples one of the rotational members of the second planetary gear set to the differential. When the actuator is in the high range position, the actuator rotationally couples another of the rotational members of the second planetary gear set to the differential.
US09821652B2 Structure for opening and closing fuel filler opening
A structure for opening and closing a fuel filler opening having a main flap and a dust flap that are opened or closed in accordance with insertion or removal of a fuel gun to a filler pipe. The dust flap is arranged at an outer end side with respect to the main flap, and is constituted by a plurality of flaps arranged flush with each other. The dust flap is opened such that ends of the respective flaps are separated from each other by the fuel gun inserted into the filler pipe.
US09821648B2 Hybrid vehicle drive device
A hybrid vehicle drive device includes a power transmission mechanism including a transmission coupled to an engine output shaft, a clutch coupled to a transmission output shaft, a first gear coupled to a clutch output shaft, a final reduction gear that constantly meshes with the first gear, a drive shaft coupled to the final reduction gear, a first rotary element coupled to an electric motor, and a second rotary element that meshes with the final reduction gear and rotates in accordance with the rotation of the rotary element. The power transmission mechanism is disposed so that, when viewed from the rotational axis direction of each gear, a line that connects the rotational axis of the first rotary element and the rotational axis of the second rotary element is inclined to the first gear side in relation to the vertical direction of the vehicle when mounted to a vehicle.
US09821646B2 Power transmission system of hybrid electric vehicle
A power transmission system may include: an engine power delivery module configured to transmit power of the engine directly to the first motor/generator as driving power for generating electricity and to selectively transmit the power of the engine as driving power for driving the vehicle, and a motor power delivery module disposed in parallel with and independently from the engine power delivery module, and configured to directly transmit power of the second motor/generator as driving power for driving the vehicle.
US09821644B1 Vehicle protection assembly
A vehicle protection assembly includes a tarp that may be draped over a vehicle thereby facilitating the tarp to substantially cover the vehicle. The tarp is substantially comprised of a resiliently compressible material. Thus, the tarp may absorb impact energy thereby facilitating the tarp to protect the vehicle from the impact energy. The tarp is substantially comprised of a non abrasive material. Thus, the tarp may resist scratching the vehicle.
US09821640B2 Door structure for vehicle
A door structure includes (i) a door panel including a first wall provided with a hinge member, a second wall, and a first bent part provided between the first wall and the second wall, (ii) a first reinforcing plate including a first part joined to the first wall, a second part joined to the second wall, and a corner part provided between the first part and the second part, and (iii) a second reinforcing plate including a third part joined to the first part, a fourth part joined to the second part, and an intermediate part provided between the third part and the fourth part. The first reinforcing plate and the second reinforcing plate are configured such that a closed space is provided between the first reinforcing plate and the second reinforcing plate.
US09821632B2 Method for controlling the refrigerant pressure in an ambient heat exchanger of a refrigerant circuit
A method of controlling the refrigerant pressure in an ambient heat exchanger of a refrigerant circuit, particularly a heat pump circuit, for vehicles, in which the current temperature and the current humidity of the ambient air is measured, the current dew point temperature of the ambient air is determined from the measured temperature and humidity, and if the ambient air temperature is below 0° C. the refrigerant pressure in the refrigerant circuit is controlled by adjusting the rotational speed of a refrigerant compressor of the refrigerant circuit, the flow cross-section of a controllable expansion element of the refrigerant circuit and/or the ambient air volume flow flowing around or through the ambient heat exchanger, such that the temperature of the ambient heat exchanger is greater than the dew point temperature.
US09821630B2 Modular air conditioning system
A thermal energy storage system of a vehicle is disclosed. The thermal energy storage system includes a refrigerant circuit conveying a refrigerant therethrough. The refrigerant circuit includes an evaporator receives a flow of the refrigerant and a flow of air. The thermal energy storage system also includes a coolant circuit conveying a coolant therethrough. The coolant circuit includes a coolant heat exchanger disposed downstream from the evaporator with respect to a direction of the flow of air through the evaporator and an auxiliary heat exchanger receiving a flow of the coolant. The thermal energy storage system further includes a cold storage device in thermal communication with the coolant circuit and a WCAC in fluid communication with the auxiliary heat exchanger.
US09821627B2 Air-conditioning system for a motor vehicle
An air conditioning system for conditioning the air of a passenger compartment of a motor vehicle comprises a housing with a first and a second flow conduit for conducting air and a coolant circuit with at least two heat exchangers, wherein a first heat exchanger is arranged in the first flow conduit and a second heat exchanger is arranged in the second flow conduit. The first heat exchanger can be operated independently of the operating mode as an evaporator and the second heat exchanger can be operated independently of the operating mode as a condenser. The housing comprises at least one air conduction device with which an air mass flow conditioned in the air conditioning system can be discharged into the environment. The coolant circuit is constructed with a heat exchanger which is arranged outside of the housing and can be operated as an evaporator or as a condenser.
US09821626B2 Heating, ventilation and/or air-conditioning apparatus including an air flow channel bypassing a heat exchanger
A heating, ventilation and/or air-conditioning apparatus (1) for the passenger compartment of a motor vehicle includes a housing (2) comprising a first air inlet (3) and a second air inlet (4). The housing (2) directs an inner air flow (Fi) from the first air inlet (3) and/or the second air inlet (4) and contains at least a first heat exchanger (5). The housing (2) includes: an air flow channel (24) directing the inner air flow (Fi) in the housing (2) while bypassing the first heat exchanger (5); and an air inlet duct (23) directing the inner air flow (Fi) in the housing (2) through the first heat exchanger (5). A heating, ventilation and/or air-conditioning installation for the passenger compartment of a motor vehicle includes: an air conditioning loop through which a coolant flows. The loop includes at least one compressor, a first expansion member, an outer heat exchanger and the first heat exchanger (5). The installation also includes the heating, ventilation and/or air-conditioning apparatus (1).
US09821614B1 Tire pressure sensor mounting system
A tire pressure sensor mounting system for mounting a tire pressure sensor directly to a wheel rim. A mounting base is disposed on the wheel rim. A linear rim strap groove is disposed across a top surface of the mounting base. A plurality of side strap through-slots is transversely disposed through the side surfaces of the mounting base. A portion of a rim strap is disposed in the rim strap groove. A first locking mechanism tightly encloses the rim strap around the wheel rim to secure the mounting base on the wheel rim. A portion of a side strap is disposed through the side strap through-slot. A second locking mechanism locks the side strap around the tire pressure sensor to secure the tire pressure sensor on the mounting base.
US09821608B2 Tire and mold comprising a fluidic passage
The tire (10B) comprises a tread (12) including a running layer (14) which is intended to come into contact with the ground when the tire (10B) rolls on the ground, and a sublayer (16) located radially inwards from the running layer (14). The tread (12) comprises at least one fluid passage (22) between the sublayer (16) and the air surrounding the tire (10B). The sublayer (16) comprises a cellular material. The fluid passage (22) comprises an element chosen from a groove (20) and a cut (26), formed in the running layer (14) and extended by at least one well (28) acting as a radial extension of the element, formed between the groove (20) and/or the cut (26) and the sublayer (16). Each well (28) forms a localized part of the fluid passage (22).
US09821604B1 Quick-release connector for connecting a wheel to a leg of a barbecue grill
A quick-release connector includes an axle, a spring, a lever and a pin. The axle includes a slit in an end, an axial bore in communication with the slit, and a transverse channel in communication with the slit. The spring is inserted in the axial bore. The lever includes a slot with a longitudinal section and a transverse section. The pin is inserted in the transverse channel and the slot to pivotally connect the lever to the axle.
US09821603B2 Method of assembling a wheeled package
A method of assembling a wheeled package includes providing a package having an exterior surface with at least one cavity, and inserting a retractable caster assembly at least partially into the cavity. The retractable caster assembly includes a frame and a caster wheel assembly with a wheel and two guide members configured to be movable along slots within the frame so that: when the caster wheel assembly is at a first end of the slots the wheel is in a retracted position substantially within the cavity; and when the caster wheel assembly is at a second end of the slots the wheel is in an extended position extending from the cavity.
US09821602B2 Apparatus for transferring driving force at wheel for vehicle
An apparatus for transferring driving force at a wheel for a vehicle may include a housing of a constant velocity joint having a center of a first end portion formed to be penetrated and inserted into a hub bearing, and a step formed on an inner peripheral surface of a middle portion of the housing, a hub flange supporting an expansion part by the step by having one end portion coupled to a wheel side and another end portion inserted into the housing to thereby form the expansion part expanded in a radial direction, and a forming member installed in the housing to face the expansion part and having an outer peripheral surface supported by an inner peripheral surface of the housing.
US09821601B2 Wheel and tire assembly
A wheel assembly including a rigid wheel and a flexible tire. The rigid wheel includes a radially outer rim wall, a plurality of mounting elements, and a plurality of inflatable spacers between the mounting elements. The flexible tire may be mounted on the mounting elements of the rigid wheel such that portions of the flexible tire between the mounting elements are separated from the outer rim wall by spaces between the mounting elements and are configured to flex inwardly when subject to ground engaging pressure. The inflatable spacers limit the amount of inward flex of the inwardly flexible portions of the flexible tire.
US09821600B2 Safety deflation wheel seal design
A wheel includes an inner wheel half defining a plurality of inner bolt apertures and having a mating surface. The wheel also includes an outer wheel half defining a plurality of outer bolt apertures and having an inner surface. The plurality of outer bolt apertures are configured to be aligned with the plurality of inner bolt apertures such that each of a plurality of bolts may be received by one of the plurality of outer bolt apertures and one of the plurality of inner bolt apertures, forming a seal between the mating surface and the inner surface in response to each of the plurality of bolts being tightened. In response to a predetermined number of bolts becoming loose, a first portion of the mating surface may separate from a second portion of the inner surface, breaking the seal.
US09821590B2 Color erasing apparatus, color erasing system and color erasing control method
In accordance with one embodiment, a color erasing apparatus comprises a conveyance path, a color erasing section and a control section. The conveyance path conveys a sheet. The color erasing section erases the color of an image formed with color erasable recording agent serving as recording agent containing coloring agent the color of which can be erased by heating. The control section carries out a control, in a case where the image formed on the sheet is not an image formed with the color erasable recording agent, so that the sheet is not subjected to a color erasing processing by the color erasing section.
US09821588B2 Recording media
The present disclosure provides recording media and related methods. A recording media for printing can comprise a base paper and a backside extruded polyethylene layer on a side of the base paper. The backside extruded polyethylene layer can include a filler and an organic reagent admixed in the extruded polyethylene layer, wherein the filler and organic reagent are present in the backside extruded polyethylene layer in an amount of 20% by weight to 50% by weight based on the total weight of the backside extruded polyethylene layer.
US09821586B2 IR dyes and laser markable articles comprising such IR dyes
Infrared dyes having an infrared absorption maximum above 1130 nm with minor colouration in the visual spectrum. The infrared dyes are especially useful for producing multicolour laser marked security documents having reduced background coloration and enhanced colour gamut.
US09821581B2 Decoloring apparatus and method
A decoloring apparatus includes a sheet conveying unit, a scanner, a decoloring unit positioned downstream of the scanner, a user interface, and a controller. The user interface includes a resolution setting section configured to receive input for setting the resolution of the image to be scanned by the scanner, and a processing mode setting section configured to receive input for setting whether to execute scanning processing by the scanner and for setting whether to execute decoloring processing by the decoloring unit. The controller is configured to control contents of the user interface and to perform a mode limiting processing so that when one of the scanning processing and decoloring processing is set to be executed, the other of the scanning processing and decoloring processing cannot be set to be executed.
US09821580B2 Inkjet printer
An inkjet printer includes a main body. An ink containing unit is disposed in the main body and is configured to contain ink to be supplied. The ink containing unit includes an ink refill portion through which ink is refilled and an ink level display surface disposed on a side surface of the main body. The side surface has an opening through which a jammed sheet is removed and a first cover configured to cover the opening. The ink level display surface and the first cover are juxtaposed on the side surface in a horizontal direction.
US09821578B2 Tape printing apparatus and tape printing system
A tape printing apparatus or the like is provided, in which both smoothness and high positioning accuracy can be realized when a tape cartridge is attached and detached. The tape printing apparatus includes a cartridge mounting portion on which a tape cartridge having a core shaft portion disposed on an inner peripheral side of a wound print tape is detachably mounted, a positioning protrusion portion which protrudes from the cartridge mounting portion and engages with an inner peripheral portion of the core shaft portion of the mounted tape cartridge, and a plurality of conductive contactors which are provided in the positioning protrusion portion, in which the plurality of conductive contactors are equally disposed in a peripheral direction in the positioning protrusion portion, and bias an inner peripheral surface of the engaged core shaft portion toward the outside in a radial direction.
US09821575B2 Sheet cartridge, label creation apparatus, and control method for label creation apparatus
A sheet cartridge includes a label sheet and a cartridge case. The label sheet has plural label portions temporarily attached at a predetermined label pitch to a temporary label attachment area that is one end in a direction of width of a long backing sheet, and plural label position detection target portions provided at a detection target end portion that is an other end in a direction of width of the backing sheet and configured to indicate a print start position and a cutting position for the each label portion. The cartridge case accommodates the label sheet that is wound, in such a way that the label sheet can be reeled off, and in which cartridge case a detection opening for protruding each label position detection target portion for detection is formed.
US09821574B2 Medium holding device and recording apparatus
A medium holding device includes a large tray having a medium mounting surface; an intermediate tray having a medium mounting surface smaller than that of the large tray; a tray mounting section on which the large tray and the intermediate tray are selectively mounted; a frame body that holds a recording medium with the large tray if the large tray and the intermediate tray have separate configuration and the large tray is mounted on the tray mounting section; and a first attachment that is mounted on an inside of the frame body and holds the recording medium with the intermediate tray if the intermediate tray is mounted on the tray mounting section, and is separated from the frame body if the large tray is mounted on the tray mounting section.
US09821573B2 Thermal printing device
A thermal printing device with a thermal print head, a platen roller opposite the print head and a protective film that is movable in a closed loop, wherein the thermal print head is arranged inside the closed loop formed by the film, so as to protect the thermal paper from damage caused by mechanical scraping by the print head; a use of the printing device is also disclosed for dispensing a printed ticket in real time, the ticket being at least partly covered by an opaque patina that is removable by scraping after printing to enable what has been printed to be viewed.
US09821570B2 Medium heating device
A medium heating device includes a heater that heats a medium, and a medium support member that supports a target heating portion, which is a portion that is heated by the heater in the medium, in which the medium support member has a first component portion that is formed so that a space is provided between the medium and the first component portion when the medium is supported, and a second component portion that is in contact with the medium when the medium is supported.
US09821567B2 Fluid delivery system for ink jet printers
A fluid delivery system for use with ink jet printers, the system including a chamber housing a fluid suitable for ink jet printing; a conduit having a distal end fluidly connected to the chamber and a proximal end configured for fluid connection to an ink jet cartridge for delivering the fluid to an inkjet printer; and a magnetic valve assembly positioned inline between the opposing ends of the conduit, to regulate flow of the fluid to the proximal end. The magnetic valve assembly operates through magnetic interaction and through the movement of a float and flap.
US09821565B2 Flow path member, liquid ejecting head and liquid ejecting apparatus
The invention is to provide a liquid ejecting head including a flow path member which allows a capacity of an air bubble chamber to be increased as much as possible and in which a filter is not clogged even when the variation of a liquid consumption amount is large, and a liquid ejecting apparatus including the flow path member. Alternatively, the invention is to provide a liquid ejecting head including a flow path member which allows a capacity of an air bubble chamber to be increased as much as possible while being miniaturized in a transporting direction and a liquid ejecting apparatus including the flow path member.
US09821564B2 Method of manufacturing a liquid cartridge and a liquid cartridge for recycling
A method for manufacturing a liquid cartridge for recycling includes a preparing step and a first step. The preparing step prepares the liquid cartridge for recycling. The liquid cartridge for recycling includes a liquid accommodating portion, a flowing path, a stopper, and a valve. The first step includes a first insertion step, a first valve open step, a first injection step, a first valve close step, a first removal step, and a first mounting step. The first insertion step inserts an injection member into the stopper. The first injection step injects the liquid into the liquid accommodating portion through the injection member, after the first insertion step and the first valve open step. The first removal step removes the stopper from the opening while the valve is maintained in the closed position after the first valve close step. The first mounting step mounts a new stopper.
US09821563B2 Liquid consuming apparatus including liquid tank with rotatable cover
There is provided a liquid consuming apparatus including: a tank having a liquid storing chamber, an erected wall through which the liquid inside the liquid storage chamber is visible from outside of the tank, and an inlet which is formed to penetrate through the erected wall and via which the liquid is poured into the liquid storage chamber; a liquid consuming section which consumes the liquid stored in the liquid storing chamber; and a cover. A transmitting section and a checking section are formed in an upper surface, of the cover, under a condition that the cover is in the exposure position, the transmitting section configured to transmit information optically to a user of the liquid consuming apparatus and the checking section configured to prevent the liquid moving on a particular surface of the cover from arriving at the transmitting section.
US09821559B2 Recording apparatus
A recording apparatus includes an opening section 30 which is formed on an outside surface of a housing 25 and through which a sheet cassette 29 is inserted, ink containers 17a and 17b that store ink, cases 18 that are disposed on outside surfaces on both sides adjacent to an outside surface on which the opening section 30 of the housing 25 is formed and holds the ink containers 17a and 17b, and a tube that supplies the ink from ink containers 17a and 17b to the inside of the housing 25, in which sizes of the cases 18 on both sides are different from each other.
US09821554B2 Liquid ejecting head and liquid ejecting apparatus
A liquid ejecting head in which a flow path substrate having a communication hole communicating with a nozzle and a pressure chamber substrate having a space that is a pressure chamber are at least laminated includes: an actuator having an active section that is interposed between electrodes and applies pressure to the pressure chamber. The pressure chamber substrate has a first space positioned in a region corresponding to the active section and a second space positioned nearer to the nozzle than the first space and communicating with the first space among the spaces. The communication hole does not overlap with the first space and overlaps with at least a part of the second space in a lamination direction.
US09821553B2 Liquid discharging head
A liquid discharging head includes a support member and plural print element substrates through which a liquid is discharged. The print element substrates are disposed on the support member and provided with the liquid through a liquid supply channel formed in the support member. The sectional area of the liquid supply channel at a position corresponding to each of the print element substrates is determined in accordance with an order in which the print element substrates are provided with the liquid.
US09821551B2 Liquid ejecting apparatus and inspection ejection unit designation data generation circuit
A liquid ejecting apparatus includes an ejection unit group that is configured with a plurality of ejection units which receives a drive signal and ejects liquid; an ejection state inspection unit that inspects a state of the ejection units; and an inspection ejection unit designation data management unit that manages inspection ejection unit designation data designating the ejection unit which is an inspection target that is the ejection unit which is inspected by the ejection state inspection unit, in the ejection unit group. The inspection ejection unit designation data includes first data of a first data format that designates the ejection unit which is first inspected, and second data of a second data format that designates the ejection unit which is continuously inspected. The second data has a smaller size than the first data.
US09821550B2 Method and inkjet printer for acquiring gap information
A method is provided that is implemented on a control device connected with an inkjet printer, which includes an inkjet head having an ink discharging surface, a head scanning unit reciprocating the inkjet head relative to a recording sheet along a scanning direction parallel to the ink discharging surface, and a wave shape generating mechanism deforming the recording sheet in a predetermined wave shape that has tops of portions protruding in a first direction toward the ink discharging surface and bottoms of portions recessed in a second direction opposite to the first direction alternately arranged along the scanning direction, the method including acquiring gap information related to a gap between the ink discharging surface and each individual one of the tops and the bottoms on the recording sheet, and determining whether the gap information acquired for each individual one of the tops and the bottoms is abnormal.
US09821541B2 Laminate material bonding
Systems and techniques are provided for laminate material bonding. A bonding agent may be applied to a first layer. A second layer may be placed onto the bonding agent on the first layer to form a laminate material. The laminate material may be placed between a first piece of non-compliant material with a first piece of compliant material and a second piece of non-compliant material with a second piece of compliant material. The laminate material may be in contact with the first piece non-compliant material and the second piece of non-compliant material. Pressure may be applied to the laminate material by applying pressure to the first piece of compliant material for a curing time of the bonding agent.
US09821539B2 Method for connecting thermoplastic, coated components and plastic component
A method for connecting thermoplastic components, in which the opposing surfaces thereof are at least partially melted by introducing energy.
US09821533B2 Coextruded, crosslinked multilayer polyolefin foam structures from recycled metallized polyolefin material and methods of making the same
A physically crosslinked, closed cell continuous multilayer foam structure comprising at least one polypropylene/polyethylene coextruded foam layer is obtained. The multilayer foam structure is obtained by coextruding a multilayer structure comprising at least one foam composition layer, irradiating the coextruded structure with ionizing radiation, and continuously foaming the irradiated structure.
US09821532B2 Peel and stick waterproofing material
Disclosed is waterproofing sheeting that uses a polyester layer that provides high lateral stability and puncture resistance. The waterproof sheeting can be used in many applications including waterproof roof underlayments, waterproof sheeting for foundations, underlayment for tile and flooring and various other applications. The waterproof sheeting can be manufactured without many of the problems associated with the granular coatings of existing waterproof sheeting that create excessive wear and environmental hazards.
US09821526B2 Packing method and unit for folding a blank on a packing machine
A packing method and unit for folding a blank on a packing machine; a first suction pickup head engages a first panel of the blank inside a store; a second suction pickup head engages a second panel of the blank inside the store; the pickup heads are moved from a withdrawal position at the store to a release position at a packing conveyor, insert the blank inside a pocket on the packing conveyor; and the blank, folded into a ‘U’, is released inside the pocket on the packing conveyor; as the pickup heads are moved from the withdrawal position to the release position, a relative movement between the first pickup head and the second pickup head is produced to fold the blank into a ‘U’ before the blank is inserted into the pocket on the packing conveyor.
US09821521B2 Golf club heads including a polymeric body in which a part of a frame or base member is embedded
Wood-type golf clubs and/or golf club heads include: (a) a golf club head base member including a face member having a ball striking face; and (b) a polymeric body member engaged with the golf club head base member, wherein the polymeric body member is formed via a rotational molding process (or other centrifugal force inducing molding process) and/or engaged with the golf club head base member via a rotational molding process (or other centrifugal force inducing molding process). The polymeric body member forms at least a portion of a crown member of the club head in some structures.
US09821518B2 Precision platform assembly for three-dimensional printer
A platform assembly has a rigid support with an array of threaded passages extending therethrough; threaded posts are engaged in the threaded passages and extend above the rigid support by a distance adjusted by rotation of each threaded post in its associated threaded passage. Manually-adjusted dog point screws can provide the threaded posts, and self-locking nuts can provide the threaded passages. A platform of smooth, slightly flexible material extends over the threaded posts and has an array of mounting elements that magnetically attach to the threaded posts to hold the platform tightly against the end of each post. Adjusting the positions of the threaded posts serves to adjust the precise position and flatness of the platform surface relative to the rigid support, and with respect to a print head of a 3D printer in which the rigid support is incorporated.
US09821516B2 Ultrasonic processing device having a force sensor
The present invention concerns an apparatus for ultrasonic processing of a material web having an ultrasonic vibration unit which has a sonotrode and a converter connected thereto optionally by way of an amplitude transformer, and a counterpart tool, wherein for processing of the material web the web is moved through a gap between the sonotrode and the counterpart tool, wherein the ultrasonic vibration unit is fixed to a carriage moveable relative to the counterpart tool so that the ultrasonic vibration unit can be moved together with the carriage in the force direction, that is to say in the direction of or away from the counterpart tool, wherein there is provided a force sensor for measuring the force applied to the sonotrode by the material web. To provide a corresponding apparatus of the kind set forth in the opening part of this specification, which permits more accurate measurement of the welding force, in order to be able to continuously process by means of ultrasound even situations of use with an extremely small process bandwidth, it is proposed according to the invention that the sonotrode and the carriage are connected together by way of a sensor component which has the force sensor.
US09821514B2 Method and apparatus in the manufacture of a spirally wound and welded tube
A method and apparatus in the manufacture of a spirally wound and welded tube is disclosed. A thermoplastic profile is slid along a path on a slider arranged in an axial direction of the tube and defining a cylindrically shaped winding surface with a diameter corresponding to the inner diameter of the tube to be manufactured. The profile is directed along a spiral path towards a previous turn of said profile by means of radial rollers spaced along said spiral path by adjusting the position of the rollers: Opposite edges of said profile turns are welded together by providing an extruded welding mass between said profile turns. The welded tube is fed from the welding station by means the rollers by sliding it onto a rotating support.
US09821513B2 Method for joining metallic member and resin member to each other, manufacturing method for cooler, and cooler
A polar functional group is added onto a surface of a metallic member. A resin member contains an adhesive functional group. The adhesive functional group and the polar functional group attract each other. A method for joining the metallic member and the resin member to each other includes: heating a junction between the metallic member and the resin member while pressing the metallic member and the resin member against each other with a first load; maintaining temperature of the junction higher than melting temperature of a resin that structures the resin member while pressing the metallic member and the resin member with each other with a second load smaller than the first load; and cooling the junction to temperature lower than the melting temperature while pressing the metallic member and the resin member against each other with a third load larger than the second load.
US09821512B2 Method and apparatus for dispensing reactive two-part systems
A two-component reactive dispensing system that is pliable is comprised of an outer sausage tubular member having therein an inner sausage tubular member in which the inner tubular member is bonded to the inner surface of the outer sausage tubular member longitudinally along a portion of the outer surface of the inner tubular sausage member. The compartments formed by the inner and outer tubular sausage members are filled with materials that are reactive with each other and the ends are sealed by gathering the ends and sealed using, for example wire wrap around clips.
US09821508B2 Apparatus for applying heat shrinkable casings onto preinsulated pipe joints
An automated heat shrink device, useful for forming a connection between two tubular sections having a polymeric outer surface jacket, for example, a connection between two sections of a district heating pipeline, and a method of use thereof. The device is configured such that it requires minimal clearance to either side of the pipeline when being used.
US09821507B2 Method to fabricate pre-patterned surfaces during manufacture of complex wrinkled structures
The pattern complexity and functional value of wrinkled structures can be substantially increased by fabricating the wrinkles on pre-patterned quasi-planar substrates instead of flat substrates. This disclosure presents the methods for fabricating pre-patterned polymeric surfaces that can be subsequently used as the substrates during manufacture of complex wrinkled structures. Pre-patterned substrates are generated by imprinting the pre-patterns onto the substrates during the curing process. Suitability for post-curing use in fabrication of wrinkles is ensured by (i) delayed imprinting that occurs close to but before the gelation point and (ii) gradual alignment of pre-patterns to the direction of stretch that is applied later during manufacture of wrinkled structures.
US09821502B2 Multi-orifice deposition nozzle for additive manufacturing
An additive manufacturing extrusion head includes a nozzle for accepting and depositing a heated material onto a work surface and/or part. The nozzle includes a valve body and an internal poppet body moveable between positions to permit deposition of at least two bead sizes of heated material onto a work surface and/or part.
US09821498B2 Injection molding method and injection molding device
In an injection molding method, using a heating cylinder having on the front end thereof a discharge nozzle, a single axis screw is rotatable inside the heating cylinder, a fiber-supplying device fills reinforcing fiber into the heating cylinder, and injection molding is performed while supplying the reinforcing fiber and the resin starting material separately and supplying the reinforcing fiber on the front side of the resin starting material. The method includes a plasticization process for obtaining a specified amount of a kneaded product by retracting the screw while rotating in the normal direction to melt the resin starting material and knead reinforcing fiber into the melted resin starting material, and an injection process for discharging the kneaded product from the discharge nozzle by advancing the screw. Reinforcing fiber is supplied into the heating cylinder in the injection process.
US09821496B2 Method of forming one or more flanges on or in a hollow continuously wound structural member
A method of and apparatus for forming one or more flanges or formations, which may conveniently be inwardly facing, on or in a hollow continuously wound structural member, such as a hollow pole, the method including the steps of providing a tapered mandrel on which to continuously wind a loop of filament or filaments to form a hollow structural member, providing an end-forming plate at at least one end of the mandrel, placing one or more formers on the outside of the mandrel adjacent to and spaced from the or each end plate by a required amount to form one or more flanges when the member has been fully wound and set within a resin, and subsequently removing the continuously wound structural member from the mandrel.
US09821488B2 Separating device
A separating device for separating a continuous single piece of material into individual work pieces includes an supporting block, a moving assembly, a separating assembly and an controller. The supporting block defines a feeding portion for the single material to pass through. The moving assembly is connected to the feeding portion and blows into the feeding portion to push individual work pieces to move along the feeding portion. The separating assembly is positioned on the supporting block. The controller is positioned on either side of the supporting block for recording and signaling the creation of an individual work piece. When the controller signals another work piece, the first separating element presses a following work piece.
US09821486B2 Integrated lamellae extraction station
An integrated station for extracting specimens suitable for viewing by a transmission electron microscope from a patterned semiconductor wafer, including a wafer cassette holder; a wafer transfer device; a nanomachining device, including a scanning electron microscope and a focused ion beam, a vacuum load lock and an operator control device, and wherein the operator control device notes locations of created lamellae; a plucker device; a control computer, adapted to control the wafer transfer device and the plucker device, commanding the plucker device to remover lamellae at the locations noted by the operator control device; and a user monitor and data input device, communicatively coupled to the computer. The wafer transfer device can transfer wafers from the wafer cassette holder to the vacuum load lock; from the vacuum load lock to the plucker device and from the plucker device to the wafer cassette holder.
US09821476B2 Articulated device with visualization system
An articulated device may include a first steerable multi-linked mechanism and a second steerable multi-linked mechanism. The second steerable multi-linked mechanism may include a first link, a plurality of intermediate links and a second link movably coupled to a second one of the intermediate links. A first one of the intermediate links may be movably coupled to the first link. The articulated device may include a camera located within at least a portion of the second link and a protective shield connected to a distal end of the second link. The protective shield may surround at least a portion of the camera.
US09821468B2 Robotic device tester
A system, method, and device may include software and hardware which simplify and quicken configuration of the system for testing a device, enhance testing procedures which may be performed, and provide data via which to easily discern a cause and nature of an error which may result during testing. A camera may capture still images of a display screen of a tested device and another camera may capture video images of the tested device and a partner device. A wizard may be used to generate a configuration file based on one previously generated for a similar device. A mount for a tested device may be structured so that: it is suitable for mounting thereon a plurality of differently structured devices; and adjustments in a vertical direction and a horizontal direction in a plane and adjustments of an angle of the device relative to the plane may be easily made.
US09821464B2 Random-access robotic inventory dispensary: operation prioritization
The present application is directed to a robotic system for maintaining product inventory and dispensing products upon request from a customer or other user. Product items are stored in an inventory storage unit (ISU), one item per bin. Controller logic allows items to be stored in, and retrieved from, arbitrarily-assigned storage locations. The bins hang on rails within drawers. Upon a request from a consumer (or other user) in a fulfillment operation, the robot retrieves a bin holding the first item from the ISU. Upon a request from an operator (or other user) in a replenishment operation, the robot transfers an empty bin to an operator station (such as a replenishing unit). The controller logic allows the fulfillment operations to be prioritized over the replenishment operations, in addition to the implementation of other prioritizations.
US09821462B2 Method for disconnecting a manual control unit from a multi-axis robot and robot for implementing such a method
This method relates to the disconnection of a manual control unit of a multi-axis robot, including a connecting cord for connecting the unit to a controller. The cord includes an input power line and output power line for each of the two cabling circuits of an emergency stop button, and an input power line and output power line for each of the two cabling circuits of a dead man contactor. The method comprises successive steps, in which: a) an operator makes a request to disconnect the unit, b) during a predetermined length of time, the safety controller does not trigger an emergency stop based on the control of the electrical cabling circuits, c) at the end of the predetermined length of time, the safety controller does not trigger an emergency stop if and only if, on the one hand, only one of the two cabling circuits of the emergency stop button is open and, on the other hand, only one of the two cabling circuits of the dead man contactor is open.
US09821459B2 Multi-joint robot having function for repositioning arm
A multi-joint robot using substantially one sensor, capable of performing a proper repositioning motion of an arm of the robot. The controller has a disturbance torque estimating part which estimates a first disturbance torque and a second disturbance torque, by calculating a torque generated by a mass and motion of the robot and subtracting the calculated torque from the first torque and the second torque detected by a torque detecting part. The controller has a repositioning commanding part which generates a motion command for rotating each axis so that the disturbance torque is reduced, when the disturbance torque exceeds a torque threshold. Since the axis is repositioned based on the motion command, a portion of the robot pushed by the operator is repositioned, whereby the operator can easily perform one's work without using a teaching board, etc.
US09821458B1 Trajectory planning with droppable objects
Example implementations may relate to methods and systems for determining a safe trajectory for movement of an object by a robotic system. According to these various implementations, the robotic system may determine at least first and second candidate trajectories for moving the object. For at least a first point along the first candidate trajectory, the robotic system may determine a predicted cost of dropping the object at the first point along the first candidate trajectory. And for at least a second point along the second candidate trajectory, the robotic system may determine a predicted cost of dropping the object at the second point along the second candidate trajectory. Then, based on these various determined predicted costs, the robotic system may select between the first and second candidates trajectories and may then move the object along the selected trajectory.
US09821456B2 Method for the manipulation of objects by means of at least two industrial robots, and associated industrial robot
An industrial robot and method for manipulating objects using at least two industrial robots. Each robot includes a manipulator arm having multiple links arranged one after another in series and connected by adjustable joints that are adjustable under the control of at least one control device. A first manipulator arm has a first end link, and at least one second manipulator arm has a second end link. The method includes gripping the object using the first manipulator arm such that the object is connected to the first end link, and coupling a link of the at least one second manipulator arm to a link of the first manipulator arm.
US09821454B2 Link actuation device
This link actuation device includes: a proximal end side link hub; a distal end side link hub; and three or more link mechanisms which each couple the distal end side link hub to the proximal end side link hub. Each link mechanism includes: proximal side and distal side end link members, and an intermediate link member. The link mechanism is provided with an actuator which arbitrarily changes the posture of the distal end side link hub relative to the proximal end side link hub. A workpiece is disposed on the proximal end side link hub, and an end effector is disposed in the distal end side link hub so as to face inside of arrangement of the link hubs and perform work onto the workpiece.
US09821451B1 Tool holding frame
A tool holding frame has a track base, a positioning board, and at least one positioning mount. The track base has a bottom panel and two rails. Each rail has a sliding channel. The positioning board is disposed on the track base and has multiple positioning segments and multiple first engaging segments. Each positioning segment has a curved positioning groove. The first engaging segments are arranged alternately with the positioning segments. The at least one positioning mount is slidably and rotatably mounted on the track base. Each positioning mount has an annular positioning flange and multiple second engaging segments. A curved part of the positioning flange is selectively engaged with one of the positioning segments. Two of the second engaging segments are selectively engaged with one of the first engaging segments.
US09821449B2 File handle
A file handle has a body, a ferrule, a clamping assembly, and a cap. The body has a first end and a second end opposite to the first end. The ferrule is assembled at the first assembling end of the body. The clamping assembly is movably mounted in the body and has two clamping portions and a threaded hole. The two clamping portions extend through the ferrule. The two clamping portions are subjected to an elastic force and oppositely separated from each other. The threaded hole is adjacent to the second assembling end of the body. The cap is rotatably assembled at the second assembling end of the body and has a screwing stick screwed in the threaded hole. Because the space between the two clamping portions can be adjusted by turning the cap, a user can clamp a tang of a file blade by the file handle.
US09821448B2 Ergonomic thermoluminescent dosimeter adapter
The ergonomic thermoluminescent dosimeter adapter provides ergonomic design that reduces the risk of repetitive motion injury. The ergonomic thermoluminescent dosimeter adapter includes a form fitting hand trigger and a handle portion mounted on a base. The handle portion has a slot adapted to receive the TLD tool. The TLD tool inserts into the adapter and fastening devices secure the TLD tool to the adapter. In operation, the adapter base is positioned on a flat surface such as a table and adjusted to a comfortable working height until the hand trigger is in a comfortable gripping position. The adapter is held with one hand and the hand trigger is squeezed with the other hand until the targeted TLD holder opens.
US09821447B2 Cushioning slides
An apparatus (1) with a reciprocating component (3) fitted with composite cushioning slides (13) on an exterior surface (8, 9). The reciprocating component (3) is movable along a reciprocation path and the composite cushioning slide (13) includes an exterior first layer (14) and an interior second layer (15). The first layer (14) is formed with an exterior surface (16) configured and orientated to come into sliding contact with a containment surface (7) of the apparatus (1) during the reciprocating movement of the reciprocating component (3), the first layer (14) is formed from a material of predetermined friction and/or abrasion resistance properties. The interior second layer (15) is located between the first layer (14) and reciprocating component (3) and is formed from a shock-absorbing material having predetermined shock absorbing properties.
US09821446B2 Handheld power tool having a drive motor operable via a manual switch
In a handheld power tool having a drive motor operable via a manual switch for driving a drive body which is associated with a mechanical percussion mechanism and coupled to a percussion member for driving an output shaft provided with a tool receptacle, and an operating mode switchover element which is designed to switch over between a normal operation and a percussion operation of the percussion mechanism and which is coupled to the drive body being associated with the drive body, an operating device is provided for operating the operating mode switchover element which is coupled to the manual switch and which is designed to enable a switchover of the operating mode switchover element between normal operation and the percussion operation of the percussion mechanism by operating the manual switch.
US09821443B2 Ratchet wrench
A ratchet wrench includes a ratchet wheel received in a handle and having an insertion hole. The ratchet wheel further includes an outer periphery having a toothed portion and a lower section below the toothed portion. The lower section includes an annular engagement groove and a cutout intercommunicating the annular engagement groove with the insertion hole. A clip includes a notch and has a diameter slightly smaller than a spacing between upper and lower wall faces of the annular engagement groove and larger than a depth of the annular engagement groove. The clip is not on the same plane when placed flat. The maximum width between an upper edge and a lower edge of the clip is slightly larger than the spacing between the upper and lower wall faces of the annular engagement groove. The clip includes an engagement section received in the cutout and extending into the insertion hole.
US09821442B2 Methods and apparatus for an enhanced driving bit
Methods and apparatus for an enhanced driving bit according to various aspects of the present technology include a bit comprising a plurality of driving surfaces having a limited length and a shoulder portion positioned between the driving surfaces and a mid-body portion of the bit. The length of the driving surfaces is selected to allow complete insertion into a recessed socket area of a fastener such that the entire driving surface is positioned within the recessed socket area. The shoulder surface is configured to distribute localized stresses away from the driving surfaces to the mid-body portion more efficiently to reduce a potential for breakage of the driving surfaces during use.
US09821435B2 Thick cubic boron nitride (CBN) layer and manufacturing process therefor
A method for forming a stand-alone wafer or a coating on a substrate uses a composite of cubic boron nitride (cBN) particles and other materials, such as nitrides, carbides, carbonitrides, borides, oxides, and metallic phase materials. The wafer or coating may be formed of a thickness up to about 1000 microns for improved wear life. The density of material within the wafer or coating may be varied according to desired parameters, and a gradient of particle sizes for the cBN may be presented across the thickness of the material.
US09821431B2 Chemical mechanical polishing conditioner
Provided is a CMP conditioner comprising: a substrate, multiple abrasive bars, and multiple slide blocks. The substrate is divided into a central surface and an outer surface. The central surface is a recessed part. The outer surface encompasses the central surface. Multiple mounting holes are recessed from the outer surface. The abrasive bars are each respectively mounted in the mounting holes. Each of the multiple abrasive bars comprises a bar body and an abrasive particle. The abrasive particle is mounted on a top surface of the abrasive bar. The multiple slide blocks are distributed among the mounting holes of the outer surface. Each of the multiple slide blocks comprises a slide dressing surface. The present invention utilizes the slide blocks to reduce the contact between the substrate and a polishing mat efficiently. The slide blocks may decrease dissolving out of metal components within the substrate and the pollution induced.
US09821426B2 Apparatus for adding an additional rotation axis to a multi-axis tooling machine
An apparatus for adding an additional rotational axis in a multi-axis tooling machine is disclosed. The apparatus includes a base unit, an indexer disk, a securement mechanism, and a pointer mechanism. The base unit is supported by the tooling machine, and the indexer disk is supported by the base unit. The indexer disk includes a periphery with a plurality of grooves spaced at radial angles with respect to a rotation axis of the indexer disk. The securement mechanism is adjustable to a fixed state in which it prevents the indexer disk from rotating, and to a released state in which the securement mechanism releases the indexer disk for rotation. The pointer mechanism is disposed at the periphery of the indexer disk for releasable engagement with the plurality of grooves. A method for adding an additional rotation axis to a multi-axis tooling machine is also disclosed.
US09821425B2 Device for supplying subcooled liquid cryogen to cutting tools
A method for subcooling liquid cryogen that is used by a cutting tool uses the steps of dividing liquid phase cryogen between a subcooler feed line and tool feed line. The cryogen in the subcooler feed line is expanded to lower the pressure and decrease the temperature of the cryogen, and the expanded liquid cryogen from the subcooler feed line is added to the interior of a subcooler. A heat exchanger is positioned in the subcooler in contact with the expanded liquid cryogen. The cryogen in the tool feed line is subcooled below its saturation temperature by passing the cryogen through the heat exchanger, and the subcooled cryogen from the heat exchanger is supplied to the cutting tool. As a result, the subcooled cryogen supplied to the cutting tool is substantially 100% liquid cryogen without any vapor content.
US09821421B2 Low vibration cryocooled system for low temperature microscopy and spectroscopy applications
A vertical support rigidly mounted to a planar base positions and supports a cryocooler expander unit off axis and away from a sample to be examined. The sample support is likewise rigidly mounted to the planar base with a rigidly mounted sample housing therein. The cryocooler expander unit is suspended in the vertical support by spring dampening bearings. A pair of opposing flexible vacuum bellows connects the cryocooler expander unit to the sample housing and vertical support. This configuration isolates the sample from vibration. Flexible thermal links associated with a predictive electronic closed loop control sequence maintains sample temperature.
US09821417B2 System and method for replacing a pitch bearing
The present disclosure is directed to systems and methods for removing or installing a pitch bearing of a wind turbine. The method includes installing a first pulley block at an up-tower location of the wind turbine and configuring a second pulley block with the pitch bearing. A pulley cable is routed from a ground location over the first pulley block to the second pulley block such that the second pulley block is configured to slide along the pulley cable. The method also includes rotating the pitch bearing to a tilted position. Thus, the method further includes lowering or lifting the pitch bearing in the tilted position so as to prevent the pitch bearing from colliding with the tower.
US09821411B2 Apparatuses, systems and methods for three-dimensional printing
The present disclosure provides three-dimensional (3D) objects, 3D printing processes, as well as methods, apparatuses and systems for the production of a 3D object. Methods, apparatuses and systems of the present disclosure may reduce or eliminate the need for auxiliary supports. The present disclosure provides three dimensional (3D) objects printed utilizing the printing processes, methods, apparatuses and systems described herein.
US09821410B2 Turbocharger shaft and wheel assembly
A system can include a controller; a force applicator; a rotatable shaft centering collet; a drive mechanism that rotates the rotatable shaft centering collect; and a laser beam unit.
US09821408B2 Laser machining method and laser machining device
Laser light L is converged at an object to be processed 1, so as to form a modified region 7 including a modified spot S in the object 1. At this time, the laser light L is converged at a front face 3 of the object 1 while an aberration of the laser light L is corrected such as to locate a converging point of the laser light L near the front face 3 serving as a laser light entrance surface, so as to form a second modified spot S2 exposed at the front face 3 in the object 1.
US09821400B2 Manual welding apparatus having an automatic wire retract method
A method providing a manual welding apparatus configured to supply a welding wire to a welding gun. The welding gun has a trigger and an opening where the welding wire extends when the trigger is activated. The method also has a computer with a user interface that includes an automatic wire retract program. The program monitors the welding gun and determines when the trigger is disabled. The program indicates when a first condition is satisfied and retracts the welding wire so the welding wire does not extend from the opening of the welding gun.
US09821399B1 Wire arc accuracy adjustment system
Provided are a systems and methods for continuously providing a metal wire to a welding torch in the correct orientation with respect to the heat source of the welding torch for manufacturing objects by solid freeform fabrication to provide continuous deposition of metal to the freeform object, especially objects made with titanium or titanium alloy, or nickel or nickel alloy, wire.
US09821393B2 Cutting tool for trimming workpiece
A cutting tool includes a body including a connecting end, a cutting end which includes a space for receiving the work piece, at least one projection with a ridge defining at least one cutting edge for cutting the work piece, and at least one slot for allowing pieces trimmed from the workpiece to exit from the body. The space has a top and a bottom and tapers outwardly from the top to the bottom. The at least one cutting edge has a first end adjacent to the top of the space and a second end adjacent to the bottom of the space and extends from the first end to the second end obliquely. The body is rotatable about a first axis, and the first axis extends longitudinally between the first and second ends of the body.
US09821392B2 Rotary machining apparatus and machining method using the same
A rotary machining apparatus that includes a rotary that supports and rotates a workpiece having helical teeth; a grinding wheel that grinds the helical teeth of the workpiece to be rotated by the rotary with grinding teeth; and a conveyor for carrying the workpiece in and out of the rotary, wherein the conveyor includes, around a turning center axis, a plurality of grippers for sandwiching the workpiece and a plurality of dressers for forming toothed surfaces of the grinding teeth, and turns around the turning center axis so that the grippers sequentially approach the rotary and the dressers sequentially approach the grinding wheel, and dress teeth of the dressers each have different shapes of toothed surfaces.
US09821391B2 Saw blade and method for arranging saw teeth
A saw blade includes a group A (group A1 [=straight tooth+the odd number of set teeth]+group A2 [=straight tooth+the even number of set teeth]) and a group B (group B1 [=straight tooth+the odd number of set teeth having opposite set-bending sides to those in the group A1]+group B2 [=straight tooth+the even number of set teeth having opposite set-bending sides to those in the group A2]). Wide and narrow set teeth are arranged so that a max/min ratio of the number of pitches between the narrow set teeth having identical set-bending side and set width is 1.8 or less, and a max/min ratio of the number of pitches between the wide set teeth having identical set-bending side set width is 2.7 or less.
US09821387B2 Machine for breaking a connecting rod
Machine for cracking a connecting rod having a small end and a big end, into a rod part and a cap part, the machine including positioning elements for positioning the connecting rod in a position for cracking, and an expandable element arranged to be inserted into a bore in said big end of the connecting rod so as to allow for splitting of the connecting rod into a rod part and a cap part by expanding the expandable element, where the machine further includes an electro press with a servomotor for actuating the expandable element.
US09821384B2 Cutting insert, cutting tool and method for manufacturing cut product
A cutting insert includes an end cutting edge, a first major cutting edge, and a second major cutting edge. The height of the end cutting edge relative to an imaginary plane orthogonal to a central axis of a through-hole is fixed. The height of the first major cutting edge relative to the imaginary plane increases, when viewed from a side, moving away from the end cutting edge. The height of the second major cutting edge relative to the imaginary plane decreases, when viewed from a side, moving away from the first major cutting edge. When viewed from a side, the angle of inclination, relative to the imaginary plane, of an imaginary line connecting both ends of the second major cutting edge is greater than an angle of inclination, relative to the imaginary plane, of an imaginary line connecting both ends of the first major cutting edge.
US09821370B2 Mold device for forming metal in high-level vacuum environment
A mold device for forming metal in a high-level vacuum environment. The mold device comprises a fixed mold, a movable mold adjoining the upper portion of the fixed mold to form a mold cavity, a closing plate placed closely on top of the movable mold, and an ejector pin extending through the closing plate and the movable mold into the mold cavity. Packing is disposed in a hole in the closing plate through which the ejector pin extends, thereby preventing atmospheric air from entering the mold cavity. There is a blocking space between the movable mold and the packing to prevent heat from being transferred to the packing. An exhaust unit creates a vacuum environment by drawing air from the mold cavity. The metal product is pushed out by the ejector pin.
US09821369B2 Rolling method for strip and corresponding rolling line
Rolling method for the production of flat products with low productivity, which includes a continuous casting step at a speed between 3.5 m/min and 6 m/min of a thin slab with a thickness between 25 and 50 mm. It also includes a roughing step to reduce the thickness in at least one roughing stand to a value between 6 mm and 40 mm, and suitable for winding, a rapid heating step by means of induction in order to at least restore the temperature lost in the segment downstream of casting and in the roughing step, a winding/unwinding step in a winding/unwinding device with two mandrels. The method also includes a rolling step in a rolling unit that consists of a single reversing stand of the Steckel type to roll the product unwound by the winding/unwinding device.
US09821367B2 Four-die tool and forging press
The invention relates to a four-die press tool (1), comprising a lower die assembly (4) and an upper die assembly (6) displaceable relative thereto, comprising four rams (10, 11, 12, 13) spaced apart and supported on the lower die assembly (4) or the upper die assembly (6) and carrying forging dies (29), and a ring (20) on which are mounted the four rams (10, 11, 12, 13) concentrically around the central press axis (28) of the four-die press tool (1) in such a way that they can be displaced relative to the central press axis (28) whenever the upper die assembly (6) is moved relative to the lower die assembly (4), wherein protecting means (35) are mounted on the ring (20) to secure a workpiece in a centered position on a central predetermined position of the workpiece relative to the central press axis (28) independently of a workpiece manipulator.
US09821363B2 Radial compression device with constrained dies
A radial compression mechanism includes a constraining structure with a cut-out defined by a plurality of bearing surfaces. A plurality of die are carried by the constraining structure and arranged in a circular pattern about a central axis. Each die has a base side positioned in parallel juxtaposition to a corresponding bearing surface and each die is constrained to move reciprocally and linearly along the corresponding bearing surface. Working surfaces of the plurality of die cooperate to form a cavity that is movable between an open position and a closed position. A driving mechanism is coupled to at least one of the plurality of die to drive all of the die in unison between the open position and the closed position.
US09821362B2 Device for the stabilisation of drain and/or fill valves for a flexible container intended for the transportation of liquids or pulverulent materials
The device for stabilizing drain and/or fill valves for a flexible container for conveying liquids or pulverulent materials is characterized by use of a non-strictly cylindrical valve comprising at least one of the following three members: a lug in a low position formed by an extension of a through valve key, a polygonal proximal flange or a partially polygonal protuberance, and in that a stabilizing plate has both a recess corresponding to and following the shape of the said chosen member, and two pads of loops and hooks stuck to the proximal surface and intended to co-operate with pads of loops and hooks sewn and/or stuck to the outer surface of the flexible container opposite the said first pads, the resulting device, when assembled, preventing the valve from rotating on itself when a drain pipe and/or fill pipe is screwed to or unscrewed from the valve.
US09821356B2 Static dissipative fluid conveying coupler and methods of assembling the same
A rigid coupler for use in electrically isolating an electrically conductive fluid conveyance system is described. The rigid coupler includes a nonconductive liner having a first end configured to couple to a first adjoining section of the fluid conveyance system, and a second end, opposite said first end, configured to couple to a second adjoining section of the fluid conveyance system. A reinforcing structure circumscribes the nonconductive liner and is coupled to a portion of the nonconductive liner extending between the first and second ends of the nonconductive liner. The reinforcing structure includes a multi-axial braided fiber material impregnated with a matrix material. A fiber overwrap is hoop wound about at a least a portion of the reinforcing structure between the first and second ends of the nonconductive liner.
US09821349B2 Wands for gas turbine engine cleaning
Wands are used as parts of cleaning systems to conduct cleaning agents into gas turbine engine cores. Wands according to the present disclosure include inlet assemblies adapted to connect to cleaning agents, dispensers adapted to discharge cleaners into gas turbine engines, and conduits that extend from the inlet assemblies to the dispensers.
US09821344B2 Systems and methods for scanning information from storage area contents
The present invention is related to methods and systems for collected item information for stored items. In one embodiment, a networked food storage system comprises a first sensor configured to read information from item tags coupled to items, wherein the items are stored or intended to be stored in a storage unit. A data store is configured to store food preferences for at least a first user. Instructions, stored in computer readable memory, are configured to: cause a first user interface to be displayed to the first user via which the first user can request a meal suggestion; retrieve preference information for the first user from computer readable memory; retrieve information read from at least a first item tag; and provide a meal suggestion based at least in part on preference information for the first user and item tag information.
US09821341B2 Apparatus for generating mechanical oscillations and a method for determining the resonance frequency of such apparatus
A device for generating mechanical oscillations is provided. The device has a first mass, a second mass, and a piezoelectric excitation system mechanically coupling the first mass and the second mass to one another, with the piezoelectric excitation system having a stiffness. The piezoelectric excitation system is designed such that its stiffness is settable.
US09821340B2 High displacement ultrasonic transducer
In some examples, a transducer apparatus includes a spring structure that enables a large, reliable amount of displacement of a transducer plate. For instance, an individual cell of the transducer apparatus may include a substrate having a first electrode portion, with at least one spring anchor extending from a first side of the substrate. At least one spring member may be supported by the at least one anchor, and may be connected to a plate that includes a second electrode portion. Accordingly, the spring member may support the plate, at least in part, for enabling the plate to move in a resilient manner toward and away from the substrate. In some cases, the spring member may be a bar-shaped spring that is cantilevered to an anchor or supported by two or more anchors. Additionally, a cavity between the plate and the substrate may be sealed by a sealing material.
US09821336B2 Multi function painter's tool box
A multi function painter's tool box apparatus enabling a user to protect, store and transport various painting tools; clean and spin dry various paint roller covers from water soluble paints and/or stains by using free a hand method with a garden hose or other flexible hose and household water pressure, by generating a jet spray with a nozzle or restricting the flow otherwise, through the rectangular washing slot and generating a high speed whirling motion to the roller; clean paintbrushes from water soluble paints and/or stains, using this single apparatus. The apparatus includes a vertically oriented box with door, a universal paint roller holder assembly, a paintbrush cleaning surface and various holders for the painting tools. It also has a rectangular washing slot on top with a splashguard and drain holes on the bottom. It has a carrying handle on the top and legs on the bottom.
US09821333B2 Fluid dispenser
One aspect of the invention provides a component 112, 165 for a fluid dispenser 110 which defines a dosing chamber 120 for a piston member 114 to stroke in and has an end 160 adapted for engaging a fluid outlet 152 of the fluid dispenser or a seal 154 which overlies the fluid outlet 152 to selectively close and open the fluid outlet 152 or seal 154. Other aspects are disclosed herein.
US09821331B2 Automatic control element with uniformly-distributed stepping frequency
An automatic control element has a sprinkler, a fluidic element connected to the sprinkler, and an outlet cover plate secured onto an outlet of the fluidic element. The fluid element further has a water inlet and a first air supply pore are symmetrically arranged on it. A second air supply pore is on the water inlet. A water distributor is formed on the sprinkler, a water tank is provided on the outer side of the sprinkler, and the water distributor is in communication with an inner cavity of the water tank. A signal nozzle is provided on the wall of the water tank, and the signal nozzle is connected to the water inlet via a conduit.
US09821328B2 Sprinkler
A sprinkler with adjustable fan angle of water sprayed is revealed. The adjustable fan angle of water sprayed means a fan area of the water sprayed is adjusted and changed. The sprinkler includes a housing, a receiving seat and a sprinkler head. The sprinkler head consists of a base seat, a collar member and an adjustment member. The fan angle of the water sprayed can be manually operated and changed by rotating the adjustment member.
US09821325B2 Apparatus and methods for lipidic cubic phase (LCP) injection for membrane protein investigations
An injector apparatus and methods for use, where the injector apparatus comprises: (a) hydraulic stage having first and second ends and including a housing defining a cavity, a primary plunger disposed in the cavity and a secondary plunger, (b) a pressurization system coupled to the hydraulic stage's first end, where the primary plunger is in fluid communication with the pressurization system and is in mechanical communication with the secondary plunger, (c) a reservoir bore defined in the hydraulic stage housing and configured to receive the primary plunger's second end, where the secondary plunger is disposed within the reservoir bore and (d) a nozzle assembly including a housing, a gas tube and a nozzle capillary, where the nozzle capillary is partially disposed in and is substantially coaxial with the gas tube, where the nozzle capillary's first end is in fluid communication with the reservoir bore's second end.
US09821324B2 Cup-shaped fluidic circuit, nozzle assembly and method
A conformal, cup-shaped fluidic nozzle engineered to generate an oscillating spray is configured as a (e.g., 100, 400, 600 or 700). Preferably, the fluidic circuit's oscillation inducing geometry 710 is molded directly into the cup's interior wall surfaces and the one-piece fluidic cup may then fitted into an actuator (e.g., 340). The fluidic cup (e.g., 100, 400, 600 or 700) conforms to the actuator stem used in typical aerosol sprayers and trigger sprayers and so replaces the prior art “swirl cup” 70 that goes over the actuator stem (e.g., 320), With the fluidic cup (e.g., 100, 400, 600 or 700) and method of the present invention, vendors of liquid products and fluids sold in commercial aerosol sprayers 20 and trigger sprayers 800 can now provide very specifically tailored or customized sprays.
US09821323B2 Droplet forming device and droplet forming method
A droplet forming device (1) for discharging a droplet in a flying fashion from a nozzle (32), the device includes a liquid chamber (29) that is communicated with the nozzle (32) and is supplied with a liquid material (37), a plunger rod (6) having a tip (34) that is moved to advance and retreat within the liquid chamber (29), a spring (8) that applies a biasing force to the plunger rod (6), a pressurization chamber (11) that is supplied with a pressurized gas (10) acting to retreat the plunger rod (6), a pressure source (15) that supplies the pressurized gas (10) to the pressurization chamber (11), and a controller (45). The droplet forming device (1) further includes a magnetic field generating mechanism (21, 22) that generates an attraction force to act in an advancing direction when the plunger rod (6) approaches a most advanced position thereof.
US09821319B2 Magnetic filter systems and methods
Magnetic filter systems may be constructed with various arrangements of permanent magnets, including but not limited to checkerboard and spiral arrangements. When coupled to a conventional filter, exemplary magnetic filter systems capture ferrous particulates against the outer wall of the conventional filter by magnetic attraction, thereby reducing the number of particulates in a fluid stream and improving the quality of the filtered fluid.
US09821313B2 Reaction vessel and apparatus and method for opening and closing a reaction vessel
A method and apparatus for opening a reaction vessel having a body forming a volume for liquid, and a lid. In the method at least one reaction vessel is placed on a transport vehicle and the reaction vessel is positioned on the vehicle so that the vessel's rotation about its own axis is prevented. Then, the at least one reaction vessel is transferred on the vehicle and a guide rod, attached to the lid that is attached by a hinge to the reaction vessel, is pushed by the movement of the vehicle against a guide surface that forces the lid to turn on the hinge so that the lid is at least partially opened.
US09821305B2 Method for heating a volume of liquid in a heated pipetting needle
The invention relates to a pipetting device for automatic analysis instruments and a method for heating a volume of liquid in a heated pipetting needle.
US09821303B2 Photocatalyst using semiconductor-carbon nanomaterial core-shell composite quantum dot and method for preparing the same
The present invention relates to a photocatalyst using a semiconductor-carbon nanomaterial core-shell composite quantum dot and a method for preparing the same, more particularly to a microparticle in which a semiconductor-carbon nanomaterial core-shell composite quantum dot is self-assembled using 4-aminophenol, capable of improving photoelectrochemical response and photoconversion efficiency when used as a photocatalyst or a photoelectrode of a photoelectrochemical device, a photoelectrochemical device using the same and a method for preparing the same.
US09821301B2 Zeolite catalysts, methods for producing zeolite catalysts, and methods for producing lower olefins
Provided are zeolite catalysts that allow reactions to proceed at temperatures as low as possible when lower olefins are produced from hydrocarbon feedstocks with low boiling points such as light naphtha, make it possible to make propylene yield higher than ethylene yield in the production of lower olefins, and have long lifetime.The zeolite catalysts are used in the production of lower olefins from hydrocarbon feedstocks with low boiling points such as light naphtha. The zeolite catalysts are MFI-type crystalline aluminosilicates containing iron atoms and have molar ratios of iron atoms to total moles of iron atoms and aluminum atoms in the range from 0.4 to 0.7. The use of the zeolite catalysts make it possible to increase propylene yield, to lower reaction temperatures, and to extend catalyst lifetime.
US09821299B2 Process for producing phosphorus modified zeolite catalysts
In a process for producing a phosphorus-modified zeolite catalyst, an aqueous reaction mixture comprising a source of silica and a source of an organic directing agent effective to direct the synthesis of a desired zeolite is heated at a temperature and for a time sufficient to produce crystals of the desired zeolite. Wet zeolite crystals can then be separated from the reaction mixture and, without removing all the water from the wet zeolite crystals, the zeolite can be converted into the ammonium form by ion exchange, and the crystals can be treated with a phosphorus compound. The phosphorus-treated, ammonium-exchanged zeolite can then be formed into a catalyst to be heated in one or more stages to remove the water and organic directing agent from the zeolite crystals and to convert the zeolite to the hydrogen form.
US09821297B2 Methods to produce molecular sieves with LTA topology and compositions derived therefrom
The present disclosure is directed to processing for preparing crystalline pure-silica and heteroatom-substituted LTA frameworks in fluoride media using a simple organic structure-directing agent (OSDA), having a structure of Formula (I): where substituents R1 to R9 are defined herein. Aluminosilicate LTA is an active catalyst for the methanol to olefins reaction with higher product selectivities to butenes as well as C5 and C6 products than the commercialized catalysts. Titanosilicate LTA is an active catalyst for the epoxidation of allyl alcohol using aqueous H2O2.
US09821296B2 Photocatalytic compositions and methods for their preparation and use
A photocatalytic composition is disclosed that includes a silver halide in combination with one or more rare earth elements. The composition may be used for the photocatalytic degradation of pollutants.
US09821295B2 Process for making a NiO-doped aluminogallate nanocomposite
The present disclosure relates to a process for producing a finely divided metal-doped aluminogallate nanocomposite comprising mixing a carrier solvent with a bulk metal-doped aluminogallate nanocomposite to form a bulk metal-doped aluminogallate slurry and atomizing the bulk metal-doped aluminogallate slurry using a low temperature collision to produce a finely divided metal-doped aluminogallate nanocomposite, the composition of a nickel-doped aluminogallate nanocomposite (GAN), and a method of NO decomposition using the nickel-doped aluminogallate nanocomposite.
US09821292B2 Apparatus for hydrocarbon removal
A hydrocarbon removal apparatus includes a plurality of fibers and a backing substrate. Each of the plurality of fibers includes a proximal end and a distal end. Each proximal end is secured to the backing substrate.
US09821290B2 Devices and methods for parahydrogen induced polarization
The present invention teaches devices and methods for hyperpolarization by parahydrogen induced polarization. The invention teaches several significant improvements over previous designs, including a heating block, an enhanced solenoid component, and pinch valves and tubing that provide a sterile environment for the sample. All of these advancements can be accomplished while keeping costs to produce the device relatively low.
US09821282B2 Diesel exhaust fluid mixing system for a linear arrangement of diesel oxidation catalyst and selective catalytic reduction filter
An exhaust system for a diesel engine, includes an exhaust passage adapted to be attached to the diesel engine. A diesel oxidation catalyst is provided in the exhaust passage along with a selective catalyst reduction device disposed downstream from the diesel oxidation catalyst. A diesel exhaust fluid mixing system includes a diesel exhaust fluid injection nozzle and a mixing device defining a single inlet opening and a single outlet opening connected to one another by a partial spiral flow passage. The diesel exhaust fluid injection nozzle injects diesel exhaust fluid directly into the inlet opening of the partial spiral flow passage.
US09821281B2 Eductor based mixer for mixing stucco and water
A mixing assembly includes a main flow conduit having an inlet end and an opposite outlet, a source of pressurized air at the inlet end, a container of stucco in fluid communication with the flow conduit, and a source of water in fluid communication with the flow conduit between the outlet and the container. The pressurized air draws stucco from the container into the flow conduit, and also draws water into the flow conduit to form an atomized slurry.
US09821278B2 Functionalized beta-sheet peptide stabilized membrane proteins, constructs comprising same, and methods of forming and using same
Constructs having membrane proteins stabilized by functionalized beta-sheet peptides are provided. The constructs can be associated with or covalently linked to supports. The support can be a membrane. The membrane can be used to selectively move desired particles from one side of the membrane to the other while impeding passage of undesired particles through the membrane. Methods of making and using such constructs and membranes are provided.
US09821275B2 Method and system for cleaning membrane filters
The disclosure relates to a system and method for cleaning filters, such as membrane filters. More particularly, a method and system are disclosed for retaining a plurality of small particulates, preferably in the shape of beads, which contact sludge or other despots on the membrane filters to remove unwanted debris that would otherwise form on the cleaning filters. In various embodiments, the plurality of small particulates are retained in a permeable enclosure formed of wedgewire.
US09821272B2 Device and method for the purification of diesel engine exhaust gases
A device and a method for reducing carbon monoxide, hydrocarbons, nitrogen oxides and soot particles present in the exhaust gases of diesel engines are provided. The device includes 1) a diesel oxidation catalyst for the oxidation of carbon monoxide, hydrocarbons and nitrogen monoxide; 2) a first unit by means of which ammonia and/or a compound that breaks down to form ammonia can be metered into the exhaust gas that is to be purified; 3) a catalytically activated particulate filter, containing a wall-flow filter substrate comprising a catalytically active material that promotes the selective catalytic reduction of nitrogen oxides to form nitrogen; 4) a second unit by means of which ammonia and/or a compound that breaks down to form ammonia can be metered into the exhaust gas that is to be purified; as well as 5) a catalyst for the selective catalytic reduction of nitrogen oxides to form nitrogen.
US09821269B2 Method and system for mixing gas and liquid for gravitational, physical and chemical collection of compounds
A method is described for mixing gas and liquid for gravitational, physical and chemical collection of compounds or particles, based on decreasing of the compounds free mean path in a vessel, and comprising the steps of: gravitational depletion, involving abating compounds and liquid chemical solution drops with higher diameter than higher volume; physical deposition, involving the condensation of abated compounds on a wet surface of the vessel; chemical adsorption, involving chemical reaction between the abated compounds and the species in the liquid chemical solution.
US09821267B2 Configurations, systems, and methods for recovery of elemental sulfur using a solvent
Elemental sulfur carrying capacity of a hydrocarbonaceous solvent is improved by first loading the solvent with sulfur and subsequent hydrotreatment under conditions that convert at least some of the elemental sulfur in the sulfur loaded solvent to hydrogen sulfide while preserving at least 95% of the monoaromatic and polyaromatic components in the solvent.
US09821266B2 Rotating bed device for the separation by adsorption of at least one constituent of a gaseous mixture
A pressure swing absorption apparatus, including: at least four beds that each include an absorbent material, wherein the at least four beds are configured to rotate and are grouped such that members of one group only have fluid interconnections with members of another group; and a control system that controls a flow rate of a fluid communication between at least two of the beds by adjusting a phase angle difference between the at least two of the beds.
US09821264B2 Adsorption air separator with dry air tap
The adsorption based air separation unit includes an adsorber vessel containing media which selectively adsorbs water vapor and nitrogen preferentially over oxygen. The vessel includes an air entry spaced from an oxygen discharge. At least one dry air tap from the adsorber vessel is located between the entry and the discharge. When the adsorption media is fresh, air entering the adsorber vessel passes through enough of the adsorber vessel to have much of its water vapor removed and only some of its nitrogen removed. The vessel can include multiple taps sequentially further from the entry which can be selectively opened as the adsorption media becomes saturated with water vapor and nitrogen, so that dry air with much of its nitrogen still present can be further tapped from the adsorber vessel. The adsorber vessel thus facilitates production of both oxygen and dry air, such as for use as medical grade air.
US09821259B2 Air cleaner
An air cleaner is provided that may include a first air cleaning module having a first fan that generates air flow from a first suction inlet toward a first discharge outlet; a second air cleaning module having a second fan that generates air flow from a second suction inlet toward a second discharge outlet; a dividing plate provided between the first air cleaning module and the second air cleaning module; and a display provided at inside of the dividing plate and in which a light source is provided.
US09821256B2 Elastically deformable component providing indication of proper fluid filter installation and related methods
An apparatus having a threaded bottom assembly for interfacing to connect the bottom assembly to a second structure with threads, having a deformable element that, when sufficient force is applied via the process of threading the bottom assembly to the second structure, and at an appropriate value of axial compression or pressure, passes from a stable state, through a rapid shape transformation to a second state via a regime of reduced resistance to deformation, creating a tactile or audible indication that the apparatus has been properly installed. The deformable element may be joined to the apparatus using a circumferential ring by friction fit or spring fit, and may adhere magnetically to the second structure to facilitation installation.
US09821254B2 System for engine oil storage and filtration in an internal combustion engine
The invention relates to a system for engine oil storage and filtration in an internal combustion engine, comprising at least one oil storage device as part of an engine oil circuit, at least one filtration device, and at least one oil delivery pump, wherein the system is characterized in that the filtration device is connected upstream of the oil delivery pump in relation to the delivery direction of the oil, with only suction filtration being provided.
US09821249B2 Continuous process for separation of proteins
Disclosed is a continuous process for separating or extracting proteins from a low grade mixture of a protein of interest, other proteins, impurities, and salts in a continuous simulated moving bed separation process. The invention provides for direct extraction of heme protein and plant protein from a crude mixture of such proteins, other proteins, impurities and salts using the chromatographic technique of simulated moving bed (SMB) continuous chromatography. The SMB process combines the steps of feed loading, adsorbent washing, product elution, adsorbent regeneration, and adsorbent equilibration. The novel strong anion exchange resin adsorbent is a quaternary amine cross-linked microcellulose wherein the microcellulose is cross-linked with epichlorohydrin and the quaternary amine is 2,3-epoxypropyltrimethyl-ammonium chloride which exhibits selective adsorption of proteins and complete regeneration. Purified protein separated in this manner may provide human health benefits by providing greater medicinal and nutrition opportunities from low quality protein sources.
US09821244B1 Magnetic wooden block toy
A magnetic wooden block toy configured to provide improved magnetic force between magnetic wooden blocks is provided. The magnetic wooden block toy includes a wooden body and at least one magnet casing embedded therein. The magnet casing includes a casing body, a flange having a sloped inner surface, and a top opening defined by the sloped inner surface. The magnet casing contains at least one magnet.
US09821241B2 Pattern-making and construction kit
A construction kit of modular components including rigid and flexible foam bars with endcaps designed to be joined together by snap-fit connections to define three-dimensional, adult-sized playing fields which float in aquatic settings such as swimming pools. The connectivity of the modular components is characterized by manual assembly, a high resistance to separation during active play by teams of adults participating in vigorous athletic activities, and tool-assisted disassembly.
US09821233B2 Methods and apparatus for distributed gaming over a mobile device
A system and method are provided for updating game participants. In some embodiments, the participants receive game control information via a one-way broadcast. The method selects a set of sampling participants from the set of all participants of a game. In some embodiments, the selection occurs prior to the start of the game. The method of some embodiments establishes a two-way connection between a server and each of the sampling participants. For some embodiments, the two-way connection is realtime. The method continuously maintains the two-way connection throughout the game. During each discrete game period, the method receives from a sampling participant, data for the sampling participant's game period performance. Based on the received data, the method determines the performance for the game period and broadcasts this information to a non-sampling participant. A non-sampling participant is a participant who was not selected for the set of sampling participants. In some embodiments, the non-sampling participant determines a standing relative to the other participants in the game event. Some embodiments provide a method and system for detecting unusual performance in a game. The game has a participant. The method calculates for the participant an average performance level. Based on the average performance level, the method tracks for the participant a participant improvement factor and stores the participant improvement factor. The method compares the participant improvement factor to a threshold value.
US09821227B2 Composing an image
The invention relates to a computer implemented method for controlling the display of a tile image on a display of the computer device, the method comprising: storing in a computer memory at the computer device, image texture data comprising a plurality of sets of predefined masks, each set of predefined masks for forming a respective tile image; selecting at random a tile image for display from a plurality of tile images; determining a location of each mask in the set of predefined masks for forming the selected tile image, in the image texture data; and supplying an indication of said location to a shader program executed on the computer device to control the shader program to use the set of predefined masks to form the selected tile image on said display.
US09821224B2 Driving simulator control with virtual skeleton
Depth-image analysis is performed with a device that analyzes a human target within an observed scene by capturing depth-images that include depth information from the observed scene. The human target is modeled with a virtual skeleton including a plurality of joints. The virtual skeleton is used as an input for controlling a driving simulation.
US09821218B2 Systems, apparatus, and methods for a game utilizing a wheel with dynamically resizable game spaces
A bingo game system provides for new features and functionality for a bingo game platform, including a dynamically resizable wheel segment for a wheel-based game.
US09821216B2 Modular barrier system
A portable ice rink includes a wall formed of multiple wall members linearly disposed adjacent to one another to form a piecewise continuous wall that encloses a desired area, and also includes a chain of links disposed on the outside of the wall members for reinforcement. The rink may further include a waterproof tarp extending underneath the wall members and folded upwards along the outer side of the wall, with its edge tied to the change of links. The tarp can contain water which then freezes to form a skating surface. Curved wall members are provided to form a rink with round corners. Each wall member is a discrete unit, made of molded plastic, and having a hollow interior which can be filled with water (or other ballast). Each wall member is designed with stiffening features to maintain the flatness of its inner surface after filling.
US09821213B2 Portable object for regattas
A race start assistance method for a boat participating in a regatta including a pre-race having a duration before the crossing of the start line, the method including a first step intended to permit the creation and storage of the start line in virtual form, and the determination of the instantaneous speed of the boat and its position with respect to the start line, in order to provide at least one indication on how to proceed in the pre-race.
US09821209B2 Golf swing analysis apparatus
A golf swing analysis apparatus capable of estimating the strike point of the ball on the face in a simple manner when a golf club is swung is provided. The apparatus is provided with a derivation unit, a calculation unit, and an estimation unit to analyze a swing using a golf club having a grip, a shaft and a head. The derivation unit derives analytical data including at least one of time-series angular velocity data and time-series acceleration data in an analysis time interval near impact, from sensor data output from at least one of an angular velocity sensor and an acceleration sensor attached to at least one of the grip and the shaft. The calculation unit calculates a feature amount of a waveform of the analytical data. The estimation unit estimates an impact position of a ball on a face of the head, according to the feature amount.
US09821206B2 Zip net pitcher safety system
A pitcher safety system may be disclosed. The pitcher safety system may be a highly portable weather resistant collapsible pitching net. The pitcher safety system may have a curved body with an opening side, a permanently closed side, a handle side, and a carriage side. A collapsible frame comprising two pivoting base members may be permanently coupled to the interior of the curved body. The collapsible frame, a first pair of connecting members, a second pair of connecting members, and a top connecting member may be quickly coupled to one another to form a fully erected frame and safety net. The pitcher safety system may have a wheeled carriage system coupled to the carriage side, a grab handle coupled to the handle side, and hinged stabilizers coupled to the underside of the permanently closed side of the curved body.
US09821204B2 Heated lacrosse stick shaft
An apparatus and method of providing heat to hand-holding locations on a lacrosse stick shaft including a heating emitting element and a user-operable control. The apparatus and method may include one or more resistive heating elements connectable to a power source such as a battery. Charging of the power source may be by plug in charging, kinetic energy charging, contact charging, inductive charging, or by replacement of a battery. The apparatus and method may be configured for mounting within the stick shaft, for being mounted in an end piece at the butt end of the shaft, or being positioned on the outside of the shaft as a sleeve or wrap. The apparatus and method may include a chemical heating apparatus or phase change heating apparatus positioned within or on the stick shaft. The user control may be mounted in or on the end piece at the butt end of the shaft. An indicator may provide information to a user regarding status states of the operation of the lacrosse stick shaft heating or recharging.
US09821203B2 Golf club head
A golf club head has a main body and a front recess that includes a flange. A rear portion of the main body includes a perimeter-weighting element. A striking face insert is secured within the front recess. A face center is located on the front surface of the striking face insert. A rear cavity is at least partially delimited by the perimeter-weighting element and a rear surface of the striking face insert. A rear insert is secured to the rear surface of the striking face insert. In an imaginary horizontal plane passing through a portion of the rear insert, proximate a heel portion of the club head, a heelwardmost point of the rear insert is spaced further from a vertical center plane than a minimum distance between the flange and the center plane. The club head comprises an auxiliary recess that extends outward from the rear cavity.
US09821198B2 Club head with sole mass element and related method
Some embodiments include a club head with sole mass element. Other embodiments of related club heads and methods are also disclosed.
US09821196B2 Luminous ball
A luminous ball is provided, including an internal sphere in which at least one receiving space is disposed; a light-emitting device disposed in the receiving space; at least one covering wrapping an external circumferential surface of the internal sphere; at least one seam formed on an edge of the covering; a plurality of thread apertures disposed in pairs at two sides of the at least one seam; at least one thread penetrating the plurality of thread apertures to stitch the edge of the covering between the two sides of the at least one seam; wherein the internal sphere is a transparent ball, a light generated by the light-emitting device penetrates the internal sphere through the receiving space, and is visible through the at least one seam and the plurality of the thread apertures distributed on the covering.
US09821191B2 All-in-one smart console for exercise machine
An all-in-one smart console, which is a self-contained unit, includes a control module for controlling an operation of the exercise machine, a command system operatively linked to the control module for receiving exercise related information from the exercise machine and data from the portable wireless communication device, and a fitness analysis module operatively linked to the control module for collecting exercise related information of the exercise machine and generating an exercise result based on the exercise related information.
US09821186B2 Multifunctional kinetic mechanism
A multifunctional kinetic mechanism includes a base including a slant tube, a counterweight unit including a joint shaft rotatably connected to the slant tube of the base, a barbell shaft having a first end piece connected to the joint shaft and a second end piece opposite to the first end piece and a counterweight attached to the second end piece of the barbell shaft, and an operating bar connected to the second end piece of the barbell shaft. Thus, by multi-directional operation of the joint shaft, a user can operate the operating bar to move the barbell shaft and the counterweight in exercising operational modes of squatting, lunging and arm lifting to train different muscle groups.
US09821184B1 Low friction rehabilitation board with an integral band retaining feature and methods of rehabilitation
A low friction rehabilitation board having an integral band retaining feature is described. The rehabilitation board may have a coefficient of static friction of no more than about 0.5 and in some embodiments no more than about 0.06. The rehabilitation board has a plurality of band retaining feature configured along one or both ends and may be an integral band retaining features being formed in the board. Additionally, the rehabilitation may include one or more band retaining features on one or both sides of the board. The unique configuration of the band retaining features enables rehabilitation method heretofore not possible with a single board. Resistance bands may be retained in the band retaining features and coupled to a user's limb, such as a foot or ankle, to resist motion, such as sliding or extending the foot along the low friction surface of the rehabilitation board.
US09821178B2 Bracket assembly
A bracket assembly includes a first flange portion with a first flange aperture. A swivel portion has first and second leg portions, each with an aperture, extending outward from a second flange portion with an aperture. The first and second leg portions define a first opening that receives the first flange portion. The first flange aperture, the first leg aperture, and the second leg aperture align and the first fastener extends therethrough. The swivel portion pivots about the first fastener in a first direction. A connector has first and second prongs, each with an aperture, defining a second opening that receives the second flange portion. The first prong aperture, the second prong aperture, and the second flange aperture align and the second fastener extends therethrough. The connector pivots about the second fastener in a second direction opposite the first direction.
US09821176B2 Rigging link belt buckle device
A rigging link belt buckle device comfortably attaches a rescue tether to a rigging link in alignment with a buckle of a belt. The device includes a buckle having a first section and a second section. The first section is selectively engageable to the second section securing the buckle in a closed position such that the buckle secures a belt to a person. A rigging link is extendable away from the buckle to define a loop with the buckle. The rigging link is configured for coupling to a tether such that force exerted on the rigging link by the tether is aligned with the buckle.
US09821173B2 Anti-cancer agents and methods of use
An anti-cancer agent includes Au(I) purinyl, indolyl, or azaindolyl analogues encapsulated in sterically hindered phosphine ligands.
US09821160B2 Visual prosthesis with an integrated visor and video processing unit
The present invention is a new configuration for the external portion of a visual prosthesis in the form of a visor or glasses, including a frame supported by a user's nose and ears. The video processing unit is adapted to be connected by temple portions of the visor and rest on the user's upper back behind the user's neck, or behind the user's head. Controls for the video processor are on one or both temple portions of the visor.
US09821157B2 Charge-enhanced neural electric stimulation system
A system and method to treat neural communication impairment is provided. The neural communication impairment is present in a neural pathway, which can be a cortico-neuromuscular pathway, an intra-brain neural pathway, or in a sensory-cortico pathway. A synchronized external stimulation is applied to a first point in proximity to a first neural component at one end of the neural pathway and to a second point in proximity to a second neural component at the other end of the neural pathway. Two induced neural handshake signals contemporaneously arrive at a neural communication impairment point in the neural pathway, triggering and stimulating a rehabilitation process by which the neural connection is permanently improved. The synchronized applied electrical signals applied to the first and second points may have an opposite polarity in dipolar neural stimulation, or may have identical polarity and waveform in in-phase neural stimulation.
US09821153B2 Punctual stimulation device
The invention relates to a device for the punctual stimulation of endings, located in the region of the ears, of nerves leading to brain stem nuclei, and device (1) having a battery-powered therapeutic current generator (3), which is arranged in a housing (2) to be worn in the ear region and is provided with an electronic circuit that forms a low-frequency therapeutic current, and said device also having at least one flexible line (5) proceeding from the therapeutic current generator (3) for connecting to an electrode to be positioned at a nerve ending and having a base electrode (7), which is likewise connected to the therapeutic current generator and by means of which the therapeutic circuit leading across the former electrode is closed, wherein the device (1), at least by means of an external part of said device (1), can be adapted to the shape of the body point of patient intended for the positioning of the device due to a mechanically pliable structure.
US09821152B1 Closure assembly
A closure assembly for a syringe having a nozzle or access portion and a discharge port including a closure cap or syringe cap having a access engaging portion removably connectible in flow restricting relation to the discharge port. A connecting structure is mounted on the access engaging portion and disposed and configured to define an interactive engagement with an attachment structure of the nozzle or access portion of the syringe. Structural and operative features of the connecting structure enable a “push-on connection” of the closure cap or syringe cap to the nozzle or access portion and a “rotate-off disconnection” of the closure cap or syringe cap from the nozzle or access portion. The closure cap or syringe cap may be used independently of or in combination with an end cap and an included indicator member, wherein the combination closure cap or syringe cap and end cap define a tamper evident cap for the syringe.
US09821148B2 Balloon catheter and method for manufacturing it
A balloon catheter includes a catheter tube and an inflatable balloon. The ends of the balloon are attached to the catheter tube. The outside surface of the balloon in an uninflated state is provided with a relief structure which in an inflated state of the balloon is substantially disappeared. A method for producing such a relief structure is by winding a wire helically around the outer surface of the balloon.
US09821144B2 Direction changing device, medical assembly having the same, and method
In one form, a direction changing device is provided including: a first mounting section; and a second mounting section, wherein an axial direction of the first mounting section and an axial direction of the second mounting section intersect each other or are parallel to each other in plan view, and in a condition where a catheter or a sheath introducer in which the catheter is inserted is mounted to the first mounting section and the second mounting section, the catheter or the sheath introducer adopts a curved shape such that a catheter or sheath introducer portion mounted to the first mounting section extends proximally to distally in one direction and a catheter or sheath introducer portion mounted to the second mounting section extends proximally to distally in another direction with the directions being different from each other.
US09821141B2 Macroporous catheter
The present invention provides a catheter for use in delivering and/or recovering materials to and/or from a tissue site in the body, the catheter comprising one or more macroporous regions adapted to selectively deliver molecules and/or recover cells from the tissue site, based on one or more physical-chemical-biological characteristics. The macroporous region can be provided in the form of a helical hollow wires, and can be adapted to both recover cells from the tissue site (e.g., bacterial or other cells present in interstitial fluid) and optionally to permit the infusion of medicament to the site, under corresponding conditions.
US09821140B2 Variable diameter tube for use in a vasal inserter for performing hemodynamics researches and related operations and method for making said tube
A variable diameter tube for use in a vessel inserter for performing hemodynamics researches and related operations comprises two coupled different-characteristic materials which are coupled to one another to provide a single stretchable tube assembly.
US09821136B2 Opening and closing device and respiratory assistance device
A respiratory assistance device 10 includes: a mask 13 having an expiratory hole 13a; an expiratory valve 15 provided in the mask 13, for opening and closing the expiratory hole 13a; and a control unit 17 for performing overall control on the entire device. The mask 13 and the expiratory valve 15 together form an opening and closing device. The expiratory valve 15 is deformable by deformation of a piezo element 15a. The expiratory valve 15 is disposed on an inner surface 13f so that a deformation direction thereof, i.e., a thickness direction thereof, extends along the inner surface 13f of the mask 13 and a side surface 15m slides along the inner surface 13f by the deformation thereof.
US09821133B2 Patient interface device having cam wheel adjustment mechanism
A patient interface device includes a support structure, a pivot arm pivotably coupled to the support structure and structured to pivot about an axis, a patient coupling member, such as a mask or a forehead support, coupled to the pivot arm, and a cam wheel rotateably coupled to the support structure and engaging the pivot arm, wherein rotation of the cam wheel relative to the support structure and the pivot arm causes the pivot arm to pivot about the axis and the patient coupling member to move either forward or backward along a path of movement. Also, an alternative patient interface device includes a cam wheel rotatable about a cushion member that changes a position of a main body portion of the cushion member relative to a headgear frame member of the patient interface device.
US09821127B2 Child-resistant closure systems for containers
A child-resistant closure system for a container comprises a protective cap, a dispensing tip, and a cylindrical base. The dispensing tip includes a pair of buttons adapted to control whether the dispensing tip is in a locked condition so as to prevent actuation or an unlocked condition so as to permit actuation, via the shoulders, of a sprayer pump unit that is partially contained within the dispensing tip. The cylindrical base has a pair of spaced apart upwardly extending legs. In an locked condition of the dispensing tip, the upwardly extending legs are not aligned with slots defined in a horizontal circumferential portion of the dispensing tip such that downward movement of the dispensing tip in relation to the base is blocked by the upwardly extending legs to prohibit actuation of the sprayer pump unit and to lock the dispensing tip.
US09821120B2 Prefilled syringe, gasket for use in prefilled syringe, and gasket production method
When a laminated gasket product is demolded from a mold in production thereof by a conventional production process, the gasket product is rubbed against the mold and, therefore, minute scratches are formed on a surface of the gasket product. The minute scratches may impair the reliable sealability of a liquid drug. A method for producing a gasket (13) for use in a prefilled syringe (10) includes the steps of: preparing a gasket forming mold; molding a gasket (13) in the mold, the gasket having a surface laminated with a lamination film (15) and including a circumferential surface portion (17); demolding the gasket (13) from the mold, and then simultaneously forming a groove (22) and a projection (24) each extending circumferentially of the gasket in a portion of the lamination film (15) present in the circumferential surface portion (17) of the gasket.
US09821119B2 Syringe assembly with pivoting plunger and integral tip guard
The invention provides a syringe assembly comprising a syringe barrel having an inside surface defining a chamber, an open proximal end, and a distal end having an opening therethrough. An elongated plunger rod extends between a first end and a second end, with a cap or guard disposed on the first end of the plunger rod. A plunger head extends within the chamber of the syringe barrel, and is adapted for slidable movement within the syringe barrel between the proximal end and the distal end, with the second end of the plunger rod connected with the plunger head through a pivotable connection. The plunger rod is adapted to pivot with respect to the plunger head between a first position in which the guard is adjacent the distal end of the syringe barrel and a second position in which the plunger rod is in general axial alignment with the syringe barrel, and is further adapted for axial movement so as to cause sliding movement of the plunger head through the syringe barrel to expel contents thereof.
US09821118B2 Automatic reconstitution for dual chamber syringe
An automatic mixing device, an actuating device removably mounted to the automatic mixing device and a retractable syringe having the automatic mixing device are provided. The actuating device has an initially compressed spring and a trigger member that initiates spring decompression to drive depression of a mixing plunger of the automatic mixing device. A seal located in the outer chamber is capable of axial movement upon depression of the mixing plunger, from a first position in sealing engagement with one or more apertures in an inner barrel to a second position intermediate the apertures and vents in an outer barrel. This allows depression of the mixing plunger to force a first substance from the outer chamber through the apertures to mix with a second substance in an inner chamber of the inner barrel. The mixed substance in the inner barrel is then delivered by the syringe with subsequent needle retraction.
US09821117B2 Wearable automatic injection device for controlled delivery of therapeutic agents
Exemplary embodiments provide wearable automatic injection devices for subcutaneously injecting a therapeutic agent into a patient's body at controlled rates, for example, in a single bolus. Exemplary embodiments provide methods for assembling wearable automatic injection devices for subcutaneously injecting a therapeutic agent into a patient's body at controlled rates. Exemplary embodiments provide methods for using wearable automatic injection devices for subcutaneously injecting a therapeutic agent into a patient's body at controlled rates.
US09821115B2 Autoinjectors
An autoinjector includes a rear body assembly (10) connected to a front body assembly, wherein the rear body assembly (10) contains a drive mechanism (60 . . . ) and the front body assembly contains a syringe (13) or cartridge with a needle at its forward end, the front body assembly including a viewing window (22) through which at least part of the contents of the syringe (13) or cartridge are visible, a removable cap (14) fitted to the forward end of the front body assembly the rear body assembly and the removable cap having respective aligned cut-away regions together defining a frame for the viewing window. Also disclosed is a modular scheme which uses a common platform for the provision of a range of autoinjectors of different fill volumes, with only the length of the plunger (60), and the axial extent of the cut out varying between different versions.
US09821114B2 Compartmentalized method of nucleic acid delivery and compositions and uses thereof
Provided herein is a method of delivering nucleic acid molecules to a compartmentalized tissue or organ of a subject. Also provided herein are uses and processes for delivering a nucleic acid molecule to the parenchyma of a compartmentalized tissue or organ. The methods and uses can be used in the treatment of diseases and conditions and in industrial, agricultural and veterinary applications. Also provided herein are compositions containing an adenovirus or adeno-associated virus or other recombinant virus formulated for administration to the parenchyma of a tissue or organ.
US09821107B2 Dialysis systems and methods
This invention relates to dialysis systems and methods. In some implementations, a method includes applying vacuum pressure to a device of a dialysis system, and then determining, based on a detected fluid level or measured pressure, whether the device is functioning properly.
US09821106B1 Apparatus for extracorporeal blood treatment and a control method therefor
An apparatus is described for extracorporeal blood treatment, comprising a treatment unit, an extracorporeal blood circuit and a fluid evacuation line. The apparatus comprises a control unit connected to a pressure sensor and configured to move a blood pump, generating a variable flow with a constant component equal to a desired blood flow value and a variable component having a nil mean value; the variable flow generates, in the expansion chamber, a pressure progression that is variable over time with a pressure component oscillating about a mean value. The control unit receives a plurality of values over a period of time comprising a plurality of oscillations of the pressure about the mean value, calculates a control value representative of the oscillating pressure component, and then determines the verification or not of a condition of variation of the blood level in the expansion chamber.
US09821101B2 Cardiac pump implantation device and method
A system and method for implanting a ventricular assist device (“VAD”) within the heart includes one or more tools, each having a body with a passage. Each tool body can be engaged with an anchor ring assembly secured to the heart. A coring tool can be advanced through the passage in a tool body and used to from a hole in the heart wall, and then valve actuating elements carried on the tool can be used to close a valve incorporated in the anchor ring assembly. A VAD can be passed into the heart through a passage in a tool body after opening the valve. The procedure can be performed while the heart continues to beat, without gross blood loss.
US09821099B2 Artificial-blood-vessel connector and artificial-blood-vessel unit
An artificial-blood-vessel connector includes: a connector portion which includes a first cylindrical body portion where a male threaded portion and a flat surface portion where the male threaded portion is not formed are alternately formed along a circumferential direction of an outer peripheral surface, and a second cylindrical body portion to be fitted inside an artificial blood vessel; a ferrule which includes a cylindrical portion to be fitted on an outer peripheral surface of the second cylindrical body portion by way of the artificial blood vessel by being made to slide linearly on a surface of the artificial blood vessel, and a pawl plate portion in contact with the flat surface portion of the first cylindrical body portion; and a nut threadedly engageable with the male threaded portion of the first cylindrical body portion in a state where the nut covers the ferrule.
US09821097B2 Body cavity drainage devices including drainage tubes having inline portions and related methods
A body cavity drainage device includes a drainage tube with a distal end configured for insertion into the body cavity of a patient, a fluid outlet at a proximal end of the drainage tube; and an activation apparatus coupled to the drainage tube between the proximal end of the drainage tube and the distal end of the drainage tube. The activation apparatus may be configured to alter a position of the distal end of the drainage tube in response to an input at a control device of the activation apparatus, and a first portion of the drainage tube extending from the activation apparatus toward the distal end may be at least substantially coaxial with a second portion of the drainage tube extending from the activation apparatus toward the proximal end. Methods relate to forming a body cavity drainage devices.
US09821094B2 Coatings for the controllable release of antimicrobial metal ions
Antimicrobial metal ion coatings. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, niobium or rhenium) on a substrate so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal.
US09821092B2 Surgical finger, hand and arm barrier coating and covering, method and system
A protective coating solution, liquid, gel, or film and a method of using such a material to provide a sterile covering for fingers, hands, arms or other selected skin surface for use as a glove substitute.
US09821089B2 Composites comprising collagen extracted from sarcophyton sp. coral
Isolated composites are disclosed comprising collagen fibers isolated from a Sarcophyton sp. coral. An exemplary composite comprises as a first component a bundle of collagen fibers, the collagen fibers being isolated from a Sarcophyton sp. coral, and a second component selected from the group consisting of a polysaccharide, a polypeptide, polylipid, a synthetic polymer, a metal and a mineral, wherein the bundle of collagen fibers comprise woven fibers, twisted fibers, braided fibers, knitted fibers, tied fibers, or sutured fibers. Uses thereof and method of generating are also disclosed.
US09821085B2 Bone treatment systems and methods
The present disclosure relates to bone cement formulations that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures together with cement injectors that include energy delivery systems for on-demand control of cement viscosity and flow parameters. The bone cement formulations may include a liquid component having at least one monomer and a non-liquid component including polymer particles and benzoyl peroxide (BPO). The non-liquid component may be further configured to allow controlled exposure of the BPO to the liquid monomer so as to enable control of the viscosity of the bone cement composition.
US09821080B2 In vivo methods of monitoring biodistribution
Non-invasive method of monitoring by radioactivity bioscanning the distribution of a biological entity in a subject in vivo by administering to the subject a radioiodinated form of the biological entity. The radioiodinated form is prepared by contacting an aqueous suspension of the biological entity with a radioiodinated construct of the structure F-S-L where F comprises a radioiodinated tyrosine moiety, S is a spacer covalently linking F to L, and L is a lipid.
US09821076B2 Chimeric VSV-G proteins as nucleic acid transfer vehicles
The design and generation of a number of chimeric VSV-G (or VSV-G variants) proteins are used as transfer vehicles to enhance delivery of nucleic acids like plasmid DNA, single and double stranded DNA and RNA, and antisense oligonucleotides into human and animal cells. These chimeric VSV-G protein-nucleic acid transfer vehicles have widespread applications to deliver nucleic acids for exon skipping and gene delivery for gene replacement in human and animals.
US09821075B2 Pharmaceutical compositions comprising meloxicam
Disclosed herein are compositions comprising an NSAID such as meloxicam in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These compositions may be orally administered, for example, to improve the bioavailability or pharmacokinetics of the NSAID for the treatment of conditions such as pain.
US09821074B2 Pyrrolobenzodiazepines and conjugates thereof
Conjugate compounds of formula (A): wherein: R2 is  where R36a and R36b are independently selected from H, F, C1-4 saturated alkyl, C2-3 alkenyl, which alkyl and alkenyl groups are optionally substituted by a group selected from C1-4 alkyl amido and C1-4 alkyl ester or, when one of R36a and R36b is H, the other is selected from nitrile and a C1-4 alkyl ester; R6 and R9 are independently selected from H, R, OH, OR, SH, SR, NH2, NHR, NRR′, NO2, Me3Sn and halo; R7 is independently selected from H, R, OH, OR, SH, SR, NH2, NHR, NRR′, NO2, Me3Sn and halo; Y is selected from formulae A1, A2, A3, A4, A5 and A6: L is a linker connected to a cell binding agent; CBA is the cell binding agent; n is an integer selected in the range of 0 to 48; RA4 is a C1-6 alkylene group; either (a) R10 is H, and R11 is OH, ORA, where RA is C1-4 alkyl; or (b) R10 and R11 form a nitrogen-carbon double bond between the nitrogen and carbon atoms to which they are bound; or (c) R10 is H and R11 is OSOzM, where z is 2 or 3 and M is a monovalent pharmaceutically acceptable cation; R and R′ are each independently selected from optionally substituted C1-12 alkyl, C3-20 heterocyclyl and C5-20 aryl groups, and optionally in relation to the group NRR′, R and R′ together with the nitrogen atom to which they are attached form an optionally substituted 4-, 5-, 6- or 7-membered heterocyclic ring; wherein R16, R17, R19, R20, R21 and R22 are as defined for R6, R7, R9, R10, R11 and R2 respectively; wherein Z is CH or N; wherein T and T′ are independently selected from a single bond or a C1-9 alkylene, which chain may be interrupted by one or more heteroatoms e.g. O, S, N(H), NMe, provided that the number of atoms in the shortest chain of atoms between X and X′ is 3 to 12 atoms; and X and X′ are independently selected from O, S and N(H).
US09821073B2 Polypeptide that binds aberrant cells and induces apoptosis
Described are proteinaceous molecules comprising at least a domain that comprises an amino acid sequence that specifically binds to an MHC-peptide complex on an aberrant cell, functionally connected with a substance that induces apoptosis in aberrant cells, but not in normal cells. These proteinaceous molecules are preferably used in selectively modulating biological processes. The provided proteinaceous molecules are of particular use in pharmaceutical compositions for the treatment of diseases related to cellular aberrancies, such as cancers.
US09821072B2 Activated neurotensin molecules and the uses thereof
The present invention relates to activated neurotensin, pharmaceutical compositions comprising the same, and the uses thereof. The compounds and compositions of the invention may be used, e.g., to reduce body temperature, attenuate or halt seizures, reduce excitotoxicity, promote neuroprotection, reduce neuroinflammation and aberrant axonal sprouting or reduce pain.
US09821070B2 Pegylated OXM variants
A composition which includes oxyntomodulin and polyethylene glycol polymer (PEG polymer) linked via a reversible linker such as 9-fluorenylmethoxycarbonyl (Fmoc) or 2-sulfo-9-fluorenylmethoxycarbonyl (FMS) is disclosed. Pharmaceutical compositions comprising the reverse pegylated oxyntomodulin and methods of using same are also disclosed.
US09821063B2 Antimicrobial compositions of aminoglycosidic antibiotics and zinc ion chelators specifically formulated for enhanced inhibition of bacterial colonization and antibacterial efficacy
Pharmaceutical compositions comprising an aminoglycosidic antibiotic and at least one zinc-chelating agent in a specified concentration, and methods of inhibiting bacterial colonization, biofilm formation and if treating bacterial infections utilizing the compositions are provided. Topical formulations suitable for wound care, and surface-applicable formulations suitable for medical, industrial and household disinfecting needs are also described.
US09821062B2 Cyanine dye compound and preparation method therefor, and dual-function agent for photodynamic therapy and preparation method therefor
Disclosed are a cyanine dye compound and a preparation method therefor, and a dual-function agent for photodynamic therapy and a preparation method therefor. The provided cyanine dye compound is connected to multiple markers, which improves the accuracy of combination of dye and tumor cells, effectively reduces the background value, and avoids excessive residues in the liver. The provided cyanine dye compound is conjugated with the photosensitizer at 2′″ position, so that tumor highly absorbs the conjugates.
US09821059B2 Composition for stabilizing protein and pharmaceutical formulation comprising the same
The present invention relates to a composition for stabilizing TNFα-binding protein exhibiting physiological activity, and more specifically, to a composition for stabilizing protein including basic amino acid and sugar and/or ammonium salt, a pharmaceutical formulation including the same, and a method for stabilizing TNFα-binding protein. The formulation including basic amino acid; and sugar and/or ammonium salt according to the present invention effectively inhibits aggregation, denaturation and oxidation of TNFα-binding protein used for treating various diseases, for example, an anti-TNF-alpha antibody, such that the protein is capable of being preserved and stored for a long time, which is widely usable and effective in a medical field using TNFα-binding protein, for example, an anti-TNF-alpha antibody.
US09821048B2 Method for treating Helicobacter pylori infections
The present invention is related to a polypeptide comprising an amino acid sequence, whereby the amino acid sequence of the polypeptide is at least 80% identical to a stretch of consecutive amino acids of the region of HPGGT comprising an amino acid sequence corresponding to SEQ.ID.No. 1, whereby such region is defined by (a) amino acid positions 150 to 200 of the amino acid sequence according to SEQ.ID.No.1, or (b) amino acid positions 410 to 480 of the amino acid sequence according to SEQ.ID.No.1, and whereby the polypeptide is suitable to elicit an immune response which is capable of inhibiting the catalytic activity of HPGGT.
US09821044B2 CD4 T cell vaccine and use thereof
The present invention relates to a CD4 T cell vaccine and a use thereof, and provides a CD4 T cell vaccine which can increase intracellular viability and effectively induce an antigen-specific cytotoxic T lymphocyte (CTL) response.
US09821043B2 Anti-HER2 vaccine based upon AAV derived multimeric structures
The present invention relates to parvovirus mutated structural proteins comprising insertions of mimotopes of a HER2, compositions, multimeric structures, medicaments and vaccines comprising the same, nucleic acids, expression cassettes, constructs, vectors and cells comprising the nucleic acids, methods of preparing the structural proteins and methods of inducing a B-cell response or of treating a HER2-related disease.
US09821042B2 Use of antagonists of ghrelin or ghrelin receptor to prevent or treat stress-sensitive psychiatric illness
The invention relates to methods of protecting against chronic stress in a subject and treating stress sensitive disorders in a subject by antagonizing ghrelin or ghrelin receptor.
US09821039B2 Albumin fusion proteins
The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acid vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention.
US09821037B1 Compounds and method of use as anti-infection compounds and therapeutic agents to regulate cholesterol metabolism
A compound is provided which comprises at least a portion of an amino acid linker-domain from squalene synthase. In alternative forms, the compound can include the amino-acid linker-domain from various fungus, including S. cerevisiae or the compound can be the functional equivalent and/or mimics an amino acid linker-domain from squalene synthase. A pharmaceutical composition includes the compound and may further include a pharmaceutical carrier. A method is provided for treating or controlling cholesterol metabolism and ergosterol metabolism in non-fungal organisms. One method includes a therapeutic treatment in humans by administering a therapeutically effective amount of the compound or pharmaceutical composition, to a patient in need of treatment, therefrom.
US09821035B2 Preparation for preventing or treating type I diabetes
The purpose of the present invention is to provide a preparation for preventing or treating type I diabetes, said preparation exerting an excellent effect of preventing or treating type I diabetes, and a method for preventing or treating type I diabetes. The onset and symptoms of type I diabetes can be very remarkably relieved by dosing a combination of: (A) at least one member selected from the group consisting of proinsulin, insulin, insulin A chain, insulin B chain, fragments thereof and variants thereof; with (B) α-GalCer.
US09821034B2 Combination therapy
The present disclosure relates to a method for treatment or prevention of diseases have an increased level of insulin-like growth factor I (IGF-I). The method comprises administration of a growth hormone (GH) variant having antagonistic activity in combination with an oligonucleotide targeted to growth hormone receptor (GHR) to a subject in need.
US09821030B2 LKKTET and/or LKKTNT peptide compositions which are lyophilized or in a form capable of being lyophilized
A composition including a peptide agent including amino acid sequence LKKTET [SEQ ID NO: 1] or LKKTNT [SEQ ID NO: 2], a conservative variant thereof, or a stimulating agent that stimulates production of an LKKTET [SEQ ID NO: 1] or LKKTNT [SEQ ID NO: 2] peptide, or a conservative variant thereof, the composition including at least one amino acid stabilizing agent or lyophilization bulking agent, the composition being in lyophilized form, or in a form capable of being lyophilized.
US09821028B2 Methods of controlling parasitic worms in animals
Disclosed herein are methods of controlling parasitic worms in herbivorous mammals and other species by orally administering an isolated antibody that specifically binds the interleukin-10 peptide or an interleukin-10 peptide. In the case of herbivorous mammals such as cattle, for example, administration of the anti-IL-10 antibodies increases weight gain and increases feed efficiency in the animals.
US09821027B2 Method for regenerating cartilage comprising applying a monovalent metal salt of alginic acid and SDF-1
A novel composition for regenerating a cartilage has been demanded, which can achieve a good effect of regenerating a hyaline cartilage that is a nearly normal cartilage without requiring the use of any transplanted cell. The present invention provides a composition for regenerating a cartilage, wherein (a) a monovalent metal salt of low endotoxin alginic acid and (b) SDF-1 are used in combination.
US09821026B2 Use of RET agonist molecules for haematopoietic stem cell expansion protocols and transplantation therapy and a RET agonist kit
The present disclosure relates to the use of RET, a transmembrane tyrosine kinase receptor, agonist molecules for Haematopoietic Stem Cell (HSC) expansion protocols and HSC transplantation therapy.RET signaling molecules are expressed by HSCs and Ret ablation leads to reduced HSC numbers. RET signals provide HSCs with critical Bcl2 and Bcl2l1 surviving cues, downstream of p38/MAP kinase and CREB activation. Accordingly, enforced expression of RET down-stream targets, Bcl2 or Bcl2l1, is sufficient to restore the activity of Ret null progenitors in vivo. Remarkably, activation of RET improves HSC survival or maintenance and in vivo transplantation efficiency, thus opening new horizons to the usage of RET agonist in HSC expansion and transplantation protocols.Additionally, the present disclosure describes a kit comprising RET agonist molecules, to be used in HSC expansion protocols and transplantation therapy.
US09821015B2 Methods of use of probiotic bifidobacteria for companion animals
According to the present invention there are provided methods of regulating the immune system of a companion animal and methods of improving the digestion of a companion animal, wherein each of said methods comprises administering to a companion animal a probiotic bacteria strain of the genus Bifidobacteria.
US09821010B2 Methods for expansion or depletion of T-regulatory cells
The invention features methods of producing compositions enriched in Tregs and methods for treating immunological disorders using these compositions. The invention also features methods for producing compositions enriched in lymphocytes and depleted of Tregs and the use of these compositions in the treatment of proliferative disorders.
US09821005B2 Polymer matrix compositions comprising a high concentration of bio-fermented sodium hyaluronate and uses thereof
The present invention relates to stable polymer matrix compositions comprising high concentrations (from about 1.5% w/w to about 3.5% w/w) sodium hyaluronate obtained from a Streptococcus zooepidemicus source and a non-ionic polymer. The polymer matrix composition further comprises polyethylene glycol and methylparaben, and utilizes ingredients that are of pharmaceutical or compendial grade. The polymer matrix compositions may optionally comprise an active ingredient. The present polymer matrix compositions may be used in the treatment of wounds, burns, certain dermatological conditions, vaginal dryness, and in topical, transdermal delivery and sustained release of active ingredients.
US09821004B2 Inhibition of a lncRNA for treatment of melanoma
This disclosure relates to the field of cancer, particularly the field of melanoma. It was found that a particular long non-coding RNA (lncRNA) is specifically up-regulated in melanoma (but not other tumor) cells as compared to melanocytes. Inhibition of this lncRNA in melanoma cells leads to induction of apoptosis and is a novel therapeutic strategy in the treatment of melanoma.
US09821000B2 Compounds, compositions and corresponding uses for preventing and/or treating of dyslipidemia
The present invention relates to the field of medicine. It relates more particularly to the use of compounds to prevent and/or treat lipotoxicity in a subject, especially lipotoxicity by hypoxia. The invention relates more particularly to compositions, especially pharmaceuticals compositions and nutritional supplements or complements comprising such compounds as well as their use to prevent and/or treat lipotoxicity, especially lipotoxicity by hypoxia. The compounds and compositions of the invention can especially be advantageously used to prevent and/or treat a pathology from among pulmonary pathologies, especially cystic fibrosis or a chronic obstructive pulmonary disease.
US09820996B2 Preparation method for antithyroid ointment for external application
A preparation method for an antithyroid ointment for external application is provided. The ointment includes the following components by mass percentage: 0.01-10% gluco corticoid, 1-15% antithyroid drug, 0.1-30% percutaneous penetration enhancer, 10-30% oleaginous base and 4-40% water-soluble base. The method includes: mixing the glucocorticoid and a drug carrier material so as to evenly disperse the glucocorticoids on the drug carrier material to obtain a glucocorticoid component; placing and evenly mixing an antithyroid drug and other ingredients in distilled water, and heating to 80° C. and evenly mixing to obtain a water phase; melting an oleaginous base and a percutaneous penetration enhancer at 80° C. and evenly mixing to obtain an oil phase; maintaining at 80° C. and pouring the oil phase into the water phase, and evenly stirring; adding the glucocorticoid component when the temperature drops to 40° C.; and evenly and sufficiently stirring until cooled to obtain an ointment.
US09820989B2 Method of treating conditions with kinase inhibitors
The present invention relates to a method of treating ophthalmic diseases and conditions, e.g. diabetic retinopathy, age-related macular degeneration, retinopathy of prematurity, etc., in a subject comprising administering to said subject a therapeutically effective amount of at least one compound of formula I or a prodrug, pharmaceutically acceptable salt, racemic mixtures or enantiomers of said compound. The compounds of formula I are capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.
US09820987B2 Modulator compounds of drug resistance in epithelial tumor cells
The described invention provides a method of treating a patient with an epithelial cancer comprising administering a composition comprising a therapeutic amount of an inhibitor of a BTK protein and one or more chemotherapeutic agent(s) selected from the group consisting of an antimetabolite, a platinum coordination compound, an alkylating agent and a combination thereof, wherein the composition is effective to reduce one or more of tumor cell growth, tumor cell clonogenicity, tumor cell proliferation, tumor cell viability and tumor volume and the therapeutic amount of the inhibitor of a BTK protein and the one or more chemotherapeutic agent(s) exerts a synergistic effect. The described invention also provides methods of treating a chemotherapy drug-resistant cancer and sensitizing a cancer patient to chemotherapy.
US09820986B2 Glycopeptide compositions
The invention include glycopeptides having a glycoside and a peptide covalently bound through an amide bond. The glycopeptides may also include a diagnostic or therapeutic agent bound to the glycopeptide. A metal, such as a radionuclide, may also be chelated to the glycopeptide. Specific embodiments of the invention relate to glycopeptides made of chitosan covalently bound to a poly(amino acid) such as poly(glutamic acid) or poly(aspartic acid). Diagnostic agents conjugated to the glycopeptide may facilitate imaging. Specific therapeutic agents that may be conjugated to the glycopeptide include anticancer drugs, rheumatoid arthritis drugs, anticoagulants, anti-angiogenesis drugs, apoptosis drugs, osteoporosis drugs, steroids, and anti-inflammatory drugs. Some agents, such as radionuclides, may have both diagnostic and therapeutic effects. The glycopeptides may be made by combining a glycoside and a peptide in the presence of a carbodiimide and an acid group activator to form an amide bond between the glycoside and the peptide.
US09820985B2 Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP)
A compound having the structure set forth in Formula (I) and Formula (II): wherein the substituents Y, Z, A, B, R1, R2, R3, R4 and R5 are as defined herein. Provided herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity.
US09820980B2 Phenyl derivative
The compound of the formula (I-1): wherein all the symbols have the same meanings as described in the specification, has two cyclic groups, particularly phenoxy groups at specific substitution positions and thus has high human S1P2 antagonistic activity. The compound may therefore be used as a therapeutic agent for S1P2-mediated diseases such as diseases resulting from vascular constriction, fibrosis, and respiratory diseases.
US09820966B2 Stabilized statin formulations
The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.
US09820965B2 Biologically active macrolides, compositions, and uses thereof
The present invention provides a compound of the formula (I) or (II), wherein R1 is H, alkyl, alkenyl or aryl, R2 is H, alkyl or aryl, R3 is H, a alkyl, alkenyl or aryl, R4 and R4-R8 are independently R10, C(O)R10 or SO2R10, wherein R10 is H, alkyl, alkenyl or aryl, and R9 is R9a, C(O)R9a or SO2R9a, wherein R9a is H, alkyl, alkenyl or aryl. R9a can be unsubstituted or substituted with one or more oxo(═O), OR9b, OC(O)R9b, OSO2R9b, NHR9b, NHC(O)R9b and NHSO2R9b groups. R9b is H, alkyl, alkenyl, or aryl. R9b can be unsubstituted or substituted with one or more groups such as oxo(═O), OR9c, CO2R9c, CO2R9c and OC(O)R9c. R9c is H, or a unsubstituted or substituted alkyl, alkenyl or aryl. The present invention further provides a composition comprising at least one compound of the present invention and a pharmaceutically acceptable carrier, alone or in combination with at least one additional active agent. The present invention further provides a method of treating a condition treatable by the inhibition of vacuolar-type (H+)-ATPase and a method of treating cancer.
US09820956B2 Compositions and methods for treating metabolic disorders
Disclosed are methods for treating a subject suffering from phenylketonuria and/or phenylalanemia. The methods include, in part, enterally administering to the subject a LNAA supplement in which the weight ratio of Leu to Val is greater than 2:1; in which the weight ratio of Leu to iLeu is greater than 3:1; or which includes one or more LNAAs and which further includes Lys. LNAA supplements are also disclosed. Also disclosed are methods for treating a subject suffering from a condition involving a metabolic disorder involving the metabolism of a first amino acid X. The method includes enterally administering to the subject a composition which (i) is substantially free from the first amino acid X and (ii) which includes a second amino acid Y that competes with amino acid X at a gastrointestinal tract transporter.
US09820955B2 GABA agonists in the treatment of disorders associated with metabolic syndrome and GABA combinations in treatment or prophylaxis of type I diabetes
In certain embodiments methods are provided for the therapeutic or prophylactic amelioration of one or more symptoms or disorders associated with metabolic syndrome. In various embodiments the methods involve administering to a subject in need thereof, a GABA receptor agonist, in an amount sufficient to ameliorate said one or more symptoms. In certain embodiments methods are provided for the prophylaxis or treatment of type I diabetes and related pathologies that involve the use of GABA or GABA agonists in combination with certain other compounds (e.g., one more antigens (e.g., GAD) that have a therapeutic effect in type I diabetes and/or an anti-CD3 antibody, an anti-CD20 antibody, exendin-4, and/or or a pro-insulin therapeutic).
US09820952B2 Solid solution compositions and use in chronic inflammation
The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.
US09820946B2 Pharmaceutical soft gelatin capsule dosage form with modified guar gum
A pharmaceutical soft gelatin capsule dosage form that includes (a) a shell that includes gelatin; and (b) a fill that includes at least one active ingredient, one or more polyethylene glycol, and a modified guar gum. The pharmaceutical soft gelatin capsule dosage form maintains its shell integrity (hardness) and fill viscosity after storage.
US09820944B1 (citric) acid/maltodextrin co-agglomerate
Methods of making and resultant acidulent/carbohydrate agglomerates. The acidulent may be citric acid having particle sizes ranging from about 1 micron to 20 microns agglomerated with a soluble carbohydrate co-agglomerate to formulate the various acidulent/carbohydrate agglomerates. In certain embodiments, the carbohydrate co-agglomerate may be maltodextrin to formulate citric acid/maltodextrin agglomerates. These citric acid/maltodextrin agglomerates are shelf stable when dry, have improved flowability, compressibility, mixability; dissolve easily and quickly in water; and provide an easy ready-to-use formulation that is suitable for use in compounding various food and pharmaceutical products.
US09820943B2 Micronized amoxicillin
The present invention relates to amoxicillin trihydrate compositions having a surface area of from 1.0 to 2.5 m2·g−1 that are free of organic contaminants such as dichloromethane, isopropanol, pivalic acid and triethyl amine and that have a purity of from 97.0% to 99.99%. Furthermore, the present invention relates to a method for the preparation of said amoxicillin trihydrate compositions and to the use of said compositions for the treatment of a bacterial infection.
US09820942B2 Lipidosome preparation, preparation method and application thereof
The present invention discloses a liposome formulation, its preparation method, and its application in the treatment of diseases caused by abnormal gene expression. The liposome formulation comprises complementary cationic lipid pairs, phospholipids, and long-circulating lipids. The method of preparing the liposome formulation comprises: mixing the complementary cationic lipid pairs with the phospholipid and the long-circulating lipid to generate pre-formed vesicles; and then mixing the pre-formed vesicles with the nucleic acid solution to generate the liposome-nucleic acid formulation. This liposome formulation provided by the present invention is easily prepared; and in the treatment of diseases caused by abnormal gene expression, the liposome formulation can be used to deliver in vivo therapeutic agents, including nucleic acids.
US09820938B2 Stable liquid formulation of AMG 416 (etelcalcetide)
A liquid formulation comprising a peptide agonist of the calcium sensing receptor and method of preparing and using the formulation are provided.
US09820937B2 Pharmaceutical composition formulated for pre-gastric absorption of monoamine oxidase B inhibitors
The invention described herein provides a fast dispersing oral solid dosage form containing monoamine oxidase B inhibitor (MAO-B inhibitor) as the active ingredient, and method of treating disease therewith, such as Parkinson's disease. In one embodiment, the monoamine oxidase B inhibitor selegiline or its analog can be the sole active ingredient in the composition administered. The dosage form composition is formulated to promote absorption through the buccal, sublingual, pharyngeal and/or esophageal mucous membrane tissue, such that at least 5% of the active ingredient is absorbed within one minute of placement in the oral cavity, as determined by a buccal absorption test. Monoamine oxidase B inhibitor compounds administered in accordance with the invention decrease the amount of undesirable metabolites associated with first pass effect of selegiline, for example, such as amphetamine and methamphetamine. The invention provides a number of other advantages over conventional orally administered tablet forms, including administration of monoamine oxidase B inhibitor compounds to patients that have difficulty swallowing.
US09820920B2 High UV protection alcohol-free emulsion system, that is clear on application
The present invention relates to a sunscreen composition comprising: a. an aqueous phase; b. an oil phase comprising at least one cosmetically acceptable oil; c. at least one sunscreen active; and d. up to about 5% by weight, based on the total weight of the composition, of an emulsifier system comprising; i. at least one ionic surfactant; ii. at least one nonionic surfactant having an HLB of greater than or equal to about 14; and iii. at least one nonionic surfactant having an HLB of less than or equal to about 10; wherein the composition is an oil-in-water emulsion containing oil droplets having an average particle size of from about 100 to 150 nm, is alcohol-free, and appears semi-transparent to transparent upon application onto an end-user's skin.
US09820916B2 Detection system for flow control apparatus
A flow control apparatus adapted to receive a feeding set includes a housing capable of receiving at least a portion of the feeding set. A pumping device is supported by the housing and positioned to contact the feeding set when the feeding set is received by the housing so the pumping device acts on the feeding set to produce fluid flow in the feeding set for delivery of fluid to a subject. An ultrasonic sensor is supported by the housing and arranged with respect to the pumping device to produce a sensor signal indicative of a viscosity of the fluid delivered through the feeding set. A control circuit is in communication with the ultrasonic sensor for receiving the sensor signal from the sensor indicative of the viscosity of the fluid and in communication with the pumping device to control operation thereof.
US09820912B2 Blood bag system
A blood bag system (10) includes a blood bag (14) to which centrifugal force is provided in a state where whole blood or a blood component is stored, and a first tube (22) that circulates a fluid centrifugally separated from the blood bag (14). The first tube (22) includes an extending portion (112) extending in an approximately perpendicular direction to a centrifugal direction into which the centrifugal force is applied. Further, a branch tube (114) that can store blood existing in the extending portion (112) is provided at a side of the centrifugal direction of the extending portion (112).
US09820908B2 Apparatus and method for rehabilitating an injured limb
A method and apparatus for rehabilitation and training of an injured limb by using the corresponding functional healthy limb to control the motion of the injured limb are presented. A sensor system on the healthy and active limb, a processing unit, and a power supply are provided in the apparatus to provide signals that activate a powered mechanism configured for moving individual bones on the injured passive limb.
US09820907B1 Multipurpose positioning device for infants
A multipurpose infant positioning device that includes a lower pad with front and back surfaces, wings attached to lateral sides of the lower pad and a bottom flap attached to the bottom portion of the lower pad. At least one of the wings and bottom flap have fastening segments attached thereto for adjustably attaching these components to portions of the lower pad. The fastened wing and bottom flap are made of a material having sufficient resiliency to maintain and bring an infant back to flexed midline position within the infant positioning device. These infant positioning devices may further include a headpiece, brim, pocket at the back surface of the lower pad and a detachable readjustable multipurpose pillow for positioning the infant from and between supine, prone and side-lying positions, all while maintaining and reinforcing the flexed midline position of the infant for normal development.
US09820903B2 Method and system for turning and positioning a patient
A device for use with a bed having a frame and a supporting surface includes a flexible sheet with a tether strap connected to the sheet and extending from the sheet. The flexible sheet has opposed top and bottom surfaces, with the top surface having a high friction material with a higher coefficient of friction as compared to the bottom surface, which includes a low friction material. The tether strap is configured for connection to the frame of the bed to secure the sheet in place. A system incorporating the flexible sheet may also include an absorbent pad configured to be placed on the top surface of the sheet, where the high-friction top surface resists sliding of the absorbent pad, as well as one or more wedges having a base wall that the wedge rests on and a ramp surface configured to confront the sheet when the wedge is placed under the sheet. The base wall and the ramp surface may also contain high friction and low friction materials, respectively.
US09820902B2 Apparatus and system for turning and positioning a patient
A system for use with a bed having a frame and a supporting surface includes a sheet having a bottom surface placed above the supporting surface of the bed, a top surface, and a plurality of tether straps connected to and extending from the sheet. Each tether strap is configured for connection to the bed. The bottom surface is at least partially formed of a low friction material, and the top surface is at least partially formed of a high friction material, such that the top surface provides greater slipping resistance than the bottom surface. The tether straps include at least two pairs of tether straps, with one pair connected proximate a top edge of the sheet and another pair connected proximate a bottom edge of the sheet. The sheet may further include a sliding member on the bottom surface to assist in lateral sliding of the sheet.
US09820900B2 Device and method for securing a mobility device in a vehicle
A device for securing a mobility device in a mobility vehicle or on a lifting device that is installed in or on a mobility vehicle or trailer. The securing device comprises a docking assembly including a first member fixedly attachable to the vehicle floor and a second member having a top and being vertically adjustably connected with the first member; an alignment rod connectable with the frame of a mobility device; a locking assembly including a tubular receiving member affixed to the top of the second member, having an opening at one end to a receiving passageway that is sized and configured to receive the alignment rod therein and having a top and a bottom and defining a slot in the top and registration opening in the bottom, the locking assembly further including a locking pin assembly mounted to the second member and operable to extend through the registration opening and lockingly engage with the alignment rod; and a guide assembly for aligning the mobility device into position for locking engagement with the receiving member.
US09820898B2 Bandage pulling tool and use of same to prepare and wrap bandages
A bandage pulling tool has a thin elongate body and a hole extending transverse to a longitudinal axis of the thin elongate body proximate an end thereof. In use, a first end of a bandage is secured to the tool using the hole by passing a first end of the bandage through the hole for use as an anchor point to the tool. With the bandage thus secured to the tool in a position passing through the hole therein, the first end of the bandage can be passed from a first side of a body portion of an injured party to another behind the body portion using the elongated shape of the tool. Accordingly, a wrap around bandage can be applied to the patient with minimal, if any, movement of potentially injured areas compared to prior art techniques of manually feeding the bandage behind the injured party.
US09820897B2 Composite liquid-retentive substrate for a hygiene article
A composite liquid-retentive substrate for a hygiene article comprises a base layer of first liquid-absorptive material. The base layer having a posterior end and a diametrically opposed anterior end interconnected by an intermediate tapered region. The posterior end has opposing posterior corners and the anterior end has opposing anterior corners. A posterior liquid-flow abutment comprising second absorptive material is disposed substantially around a perimeter of the posterior end. At least one anterior liquid-flow abutment comprising second absorptive material is disposed proximate one of the anterior corners of the anterior end.
US09820895B2 Diaper structure with enhanced tactile softness attributes
A diaper structure with enhanced softness attributes is disclosed. The diaper structure may include an innermost layer formed of a first nonwoven web, and an outermost layer formed of a second nonwoven web. The first and second nonwoven webs may have a combined basis weight of at least about 30 gsm. The ratio of the first web basis weight to the second web basis weight may range from 30/70 to 70/30.
US09820891B2 Sensor for urine and stool detection
A sensor for detecting urine and stool secretion mounted over two or more layers of garment, said sensor comprising: at least one light source configured to illuminate said garment; at least one photodetector configured to output an indication of the amount of light reflected from said garment; and an electronic circuit configured to detect said secretion by monitoring said output of said photodetector and identifying a temporal pattern being characteristic of said secretion event.
US09820886B2 Laser assisted cataract surgery
Laser assisted cataract surgery methods and devices utilizing one or more treatment laser beams to create a shaped opening in the anterior lens capsule of the eye when performing a capsulorrhexis procedure. A light absorbing agent may optionally be added onto or into the lens capsule tissue, and the treatment laser wavelength selected to be strongly absorbed by the light absorbing agent. Alternatively, the treatment laser wavelength may be selected to be absorbed or strongly absorbed by the tissue itself, in which case no additional light absorbing agent need be used. Visualization patterns produced with one or more target laser beams may be projected onto the lens capsule tissue to aid in the procedure. The devices may be attached to or integrated with microscopes.
US09820884B2 Treatment medium delivery device and methods for delivery of such treatment mediums to the eye using such delivery device
A device for delivering a treatment medium to an eye includes a first body portion configured to be removably inserted and secured in an opening of the eye, and a second body portion supported by the first body portion. At least the second body portion includes a treatment medium, and a coating having an opening through which the treatment medium elutes out of the device.
US09820883B2 Method for treating glaucoma
A method and delivery system are disclosed for creating an aqueous flow pathway in the trabecular meshwork, juxtacanalicular trabecular meshwork and Schlemm's canal of an eye for reducing elevated intraocular pressure. Pulsed laser radiation is delivered from the distal end of a fiber-optic probe sufficient to cause photoablation of selected portions of the trabecular meshwork, the juxtacanalicular trabecular meshwork and an inner wall of Schlemm's canal in the target site. The fiber-optic probe may be advanced so as to create an aperture in the inner wall of Schlemm's canal in which fluid from the anterior chamber of the eye flows. The method and delivery system may further be used on any tissue types in the body.
US09820879B2 Intestinal devices and methods for facilitating weight loss
Intestinal devices and methods for facilitating weight loss. In at least one embodiment of a method of patient treatment of the present disclosure, the method comprises the step of positioning a device, that is configured to reduce or limit localized intestinal distension, around a portion of an intestine of a patient.
US09820870B2 Weight-bearing lower extremity brace
The present disclosure relates, according to some embodiments, to a device and/or system (e.g., redistributing weight away from a subject's foot), which may comprise (a) a platform, (b) at least one vertical support fixed to the platform and extending upwardly from the platform, and (c) at least one cuff (i) configured to surround and releasably grip at least a portion of a subject's leg other than the foot and (ii) mounted (e.g., adjustably) to the at least one vertical support at a vertical position along the at least one vertical support sufficient to suspend a subject's foot in a non-weight-bearing position above the platform during ambulation, wherein the platform, the at least one vertical support, and the at least one cuff together are configured to bear at least the subject's full weight.
US09820869B2 Intervertebral pressure monitor
An instrumented distractor includes a force sensor for measuring a force exerted by opposing surfaces of adjacent vertebrae pressing against fixed and adjustable arms on the distractor. The force on the distractor may be measured by a data acquisition system (DAS). An instrumented cage including at least one force sensor may be inserted into the same intervertebral space as the distractor and a measurement of force on the cage made by the DAS. A size and shape of the instrumented cage are preferably selected such that the magnitude of force on the cage is less than or equal to the magnitude of force measured with the distractor. In some embodiments, a first DAS is included in the instrumented distractor and a second DAS is included in the insertion handle, and the two data acquisition systems may communicate measured force values with one another.
US09820866B2 Expandable spinal implant
An expandable implant device (100) for insertion between two vertebrae (400) is disclosed. The device (100) has an upper body (20), a lower body (40) and an external retainer band (60). The external retainer band (60) holds the upper body (20) and lower body (40) and has an inner surface having a plurality or set of upper ratchet teeth (80U) sloped for allowing upward movement and a plurality or set of lower ratchet teeth (80L) for allowing downward movement. The ratchet teeth (80) of the upper body (20) are mated or fitted to the upper teeth (80) of the retainer band (60) and the ratchet teeth (82) of the lower body (40) are mated or fitted to the lower ratchet teeth (82) of the retainer band (60). The height of the device (100) is increased by upward movement of the upper body (20) and downward movement of the lower body (40).
US09820852B2 Stationary intra-annular halo designs for paravalvular leak (PVL) reduction—active channel filling cuff designs
A prosthetic heart valve may include a collapsible and expandable stent extending in a flow direction between a proximal end and a distal end, a cuff attached to an annulus section of the stent and having an outer surface facing in a radial direction orthogonal to the flow direction, a plurality of prosthetic valve leaflets attached to the cuff, and a sealing structure attached to the annulus section of the stent at an inner edge of the sealing structure. The flow direction may be defined from the proximal end toward the distal end. The sealing structure may have an outer edge remote from the inner edge. The sealing structure may have a collapsed condition with the outer edge disposed adjacent the outer surface of the cuff and an expanded condition with the outer edge spaced apart from the outer surface of the cuff.
US09820848B2 Method for creating incision to improve intraocular lens placement
A system and method for insetting an intraocular lens in a patient's eye includes a light source for generating a light beam, a scanner for deflecting the light beam to form an enclosed treatment pattern that includes a registration feature, and a delivery system for delivering the enclosed treatment pattern to target tissue in the patient's eye to form an enclosed incision therein having the registration feature. An intraocular lens is placed within the enclosed incision, wherein the intraocular lens has a registration feature that engages with the registration feature of the enclosed incision. Alternately, the scanner can make a separate registration incision for a post that is connected to the intraocular lens via a strut member.
US09820846B2 Tubular vascular graft and the preparation thereof
The present invention provides a reparation method of a tubular vascular graft, (a) immersing a tubular scaffold in a first light sensitivity gelatin solution, and irradiate the tubular scaffold by a first time period, to let surface of the tubular scaffold form a base layer; (b) immersing the tubular scaffold of the step (a) in a chitin gelatin solution, when the surface of the base layer form a film, then immersing the tubular scaffold into a sodium hydroxide solution to generate a middle layer of the surface of the base layer; (c) immersing the tubular scaffold of the step (b) in a second light sensitivity gelatin solution, wherein the second light sensitivity gelatin solution comprises a cell, the tubular scaffold is irradiated by a second time period to form a surface layer of the middle layer; (d) until the cell forms a tubular structure of the surface layer by the cell in the tubular scaffold of the step (c), heating the tubular scaffold by a temperature to solve the base layer into a solution, pulling out the tubular scaffold to get an artificial blood vessels.
US09820841B2 Removable deployment system and method for implantable mesh prostheses
A medical device including a mesh prosthesis having a first mesh layer affixed to a second mesh layer along a perimeter area. An enclosure is defined between the first and second layers and extends inwardly from the perimeter area. An opening in the first layer passes through the first layer to the enclosure. A fixation guide template defines a guide pocket within the enclosure. A resilient deployment structure is removably disposed within the enclosure and extending toward the perimeter area. The resilient deployment structure has an elasticity that generates a resilient deployment force for urging the mesh prosthesis to a deployed configuration from a non-deployed configuration. A shield projection extends outwardly from a perimeter of the resilient deployment structure and is engaged within the guide pocket to prevent relative rotational movement between the resilient deployment structure and the mesh prosthesis. A method of using a medical device is also included.
US09820839B2 Single plane tissue repair patch having a locating structure
A novel single plane tissue repair patch is disclosed. The patch has a base member with an opening therethrough, and a closure member associated with the opening. Mounted to the periphery of the bottom side of the base member is a locating structure. The mesh may be used in open surgical procedures for hernia repairs and other repairs of body wall defects.
US09820838B2 Single plane tissue repair patch
A novel single plane tissue repair device such as a patch is disclosed. The device has a base member with an opening therethrough, and a closure member associated with the opening. The mesh has a biaborbable polymeric adhesion barrier attached to the bottom side of the base member about its periphery to form a pocket that is accessible through the opening. The mesh may be used in open surgical procedures for hernia repairs and other repairs of body wall defects.
US09820835B2 Dentition occlusion mapping using elastic foam modeling
A method for generating a mapping of dental occlusion generates a three-dimensional model of the patient's teeth according to acquired image data. The maxillary and mandibular arches are positioned in opposition in the generated model of the patient's teeth and a meal model generated having characteristics of a foam material. A pressure field distribution for the generated meal model is calculated for one or more pairs of opposed teeth from the generated three-dimensional model of the patient's teeth. The calculated pressure field distribution can be displayed.
US09820832B2 Vertically adjustable rotational stabilizer for a disposable articulator
A vertically adjustable rotational stabilizer (10) for a disposable articulator is provided. The articulator comprises a hinged pair of support arms, each support arm having a proximal end and a distal end, with the proximal ends of the support arms being hingedly fitted together. Each arm defines an opening or cavity between its distal and proximal ends. The vertically adjustable rotational stabilizer (10), in broad terms, comprises at least one body (30, 66) secured or securable to the support arms (14, 16) and positioned substantially within the opening defined by the support arm, and an elongate member (56) being adjustable relative to the at least one body so as to adjust and fix the distance between the distal ends of the support arms (14, 16).
US09820828B1 Removable veneers for teeth
The removable veneer for teeth is a cosmetic accessory adapted to overlay the teeth. The accessory includes a veneer designed to simulate perfectly positioned human teeth. A fastener system is employed to removably attach the veneer to the existing natural teeth of a user. Various teeth adornments may be attached to the veneer, if desired, when the wearer wants to assume a more modern look.
US09820826B2 Ultrasonic tip for ultrasonic instrument and method of dental treatment with said ultrasonic tip
The invention provides an ultrasonic tip in titanium for ultrasonic instrument, and further provides a method of dental treatment of peri-implantitis using an ultrasonic tip operable to cooperate with an ultrasonic instrument to transmit ultrasonic vibrations to a surface of a dental implant to be treated, said implant and said ultrasonic tip being made of titanium. The present invention guarantees a safe and complete debridement of most implants for the dental treatment of peri-implantitis, and for the maintenance of the implant surface after such a treatment. Designed in pure titanium, like most dental implant in the market, the tip of the present invention advantageously avoids the transfer of material on the implant and the alteration of the surface, thereby preventing the risk of bacterial recontamination.
US09820825B2 Surgical system having plurality of detachably attachable components and circuit for detecting target states of detachably attachable components and performing control based on detected target states, and method for providing surgical system
Techniques, including a surgical system and a method for providing a surgical system, for detecting detachable attachment of a first component to a console, for detecting detachable attachment of a second component to one of the console the first component, and for controlling a function module based on the detection result are provided.
US09820823B2 Grip force control for robotic surgical instrument end effector
A method of controlling an end effector of a robotically-controlled surgical instrument may include receiving a first input signal indicative of a high grip level input at a master grip input mechanism that controls a slave gripping force of the end effector; receiving a second input signal indicative of a user's readiness to operate the surgical instrument to perform a first surgical procedure; and outputting a locking signal in response to receiving the first input signal and the second input signal together to lock one or more degrees of freedom of the surgical instrument during the first surgical procedure.
US09820821B2 Customized patient-specific revision surgical instruments and method
A method of fabricating a customized patient-specific guide block is disclosed. The method includes generating a image of a patient's bony anatomy and an implanted prosthetic component secured to the patient's bony anatomy, identifying landmarks on the patient's bony anatomy and the prosthetic component, selecting a revision surgical instrument based the image and the landmarks, and manufacturing the customized patient-specific guide block including a customized prosthesis-specific negative contour shaped to match a corresponding contour of the implanted prosthetic component.
US09820820B2 Module for a visualization apparatus for viewing an object
A module for a visualization apparatus includes an imaging optic accommodated in a base body for generating a viewing image of an object region with an optical viewing beam path. The module includes a display unit for visualizing an image superimposed on the viewed image of the object region with orientation information. The module has an image acquisition unit having an image sensor for acquiring an image of the object region. The module contains a switching unit for selectively providing and blocking an optical beam path from the display to the image sensor. The switching unit, in a first switching state, provides the image of a geometric structure on the display onto the image sensor with the optical beam path and, in a further switching state blocks the optical beam path from a geometric structure on the display to the image sensor.
US09820818B2 System and method for controlling a surgical manipulator based on implant parameters
System and method for controlling a surgical manipulator to apply an energy applicator to a patient. The surgical manipulator cooperates with a navigation system to position the energy applicator with respect to a boundary so that the energy applicator is constrained from moving outside the boundary. The boundary is generated based on implant parameters measured after manufacture of the implant.
US09820816B2 Systems and methods for a dual control surgical instrument
A method comprises receiving a surgical instrument into engagement with a grip actuator of a teleoperational activation system. The surgical instrument includes movable jaws, and the surgical instrument is received in a prearranged gripping configuration with the jaws gripping a surgical accessory. The method includes generating a first control signal for manipulating the surgical instrument while maintaining the surgical instrument in the prearranged gripping configuration. The method further includes generating a second control signal for manipulating the surgical instrument to move from the prearranged gripping configuration to a second configuration.
US09820815B2 Skin treatment device with means for providing a tactile feedback signal
A skin treatment device having a treatment window for treating skin through the treatment window and a user guide to deliver a tactile feedback signal during movement in stepwise increments of the treatment window along the skin.
US09820810B2 Medical device for use in bodily lumens, for example an atrium
A medical system includes an expandable structure and a first flexible circuit. The expandable structure is sized to be received in a chamber of a heart and is selectively moveable between a delivery configuration and an expanded configuration. The expandable structure includes a plurality of metal strips. The first flexible circuit includes a first flexible electrically insulative substrate and a plurality of electrically conductive traces patterned on the first flexible electrically insulative substrate. A portion of the first flexible circuit is patterned to form at least a first transducer element, and at least a part of the first flexible circuit is at least positioned between two of the plurality of metal strips that contact the first flexible circuit when the expandable structure is in the expanded configuration.
US09820804B2 Anastomosis device with collapsible distal head element
A surgical instrument for bonding body tissue includes a shank and first and second tool elements which are movable relative to each other and include a respective electrode. The electrodes define a minimum distance from each other, are opposed to each other and face each other in an approximating position of the tool elements. The first tool element is arranged or formed at the distal end of the shank, so that a mechanical load of anastomoses of body tissue parts produced by current flow is minimized when removing the surgical instrument. The second tool element is adapted to be brought from an operating position, in which it can be brought into the approximating position, into a removing position, in which a peripheral withdrawing line defined by the electrode of the second tool element is shorter than a peripheral approximating line defined by the electrode in the approximating position.
US09820803B2 Subxiphoid connective lesion ablation system and method
Instrument and systems for applying ablative energy to epicardial tissue via a subxiphoid access surgical approach. The instrument has a head assembly sized and shaped for a subxiphoid surgical approach to a patient's heart and defines a contact face. The head assembly includes a paddle body, a first ablation electrode, and a second ablation electrode. The ablation electrodes are coupled to the paddle body in a spaced apart, spatially-fixed fashion. The ablation electrodes are exteriorly exposed at the contact face. A tubular member extends from the head assembly and maintains wiring connected to the ablation electrodes. The instrument is manipulable to locate the contact face on epicardial tissue of a patient's heart via a subxiphoid surgical approach, such as between the left and right pulmonary vein junctions of the posterior left atrium.
US09820802B1 Methods and system of temperature based alarms and/or automatic interrupt (shut-off) in fluoroscopy (medical images) based mapping system for cryoballoon ablations or radiofrequency (RF) ablations for atrial fibrillation
A method and system for increasing safety of cardiac ablation procedures comprises a computer based system that monitors the esophageal temperature, and a fluoroscopy (medical images) based cardiac mapping system for cryoballoon or radiofrequency (RF) ablations. The esophageal temperature is monitored utilizing an esophageal probe which may have any number of temperature sensing members. The esophageal probe may also have pre-formed shape. During atrial fibrillation ablations, based on a pre-determined increase in esophageal temperature (from any thermistor), the computer based system activates different levels of alarm(s), and/or initiates ablation energy interrupt based on pre-defined programmed values. The method and system is also used for guiding placement of cryoballoon and performing cryoablations. The placement of cryoballoon catheter or a circular catheter is based on superimposing a high resolution (dye injected) image and a live fluoroscopy image and adjusting transparency between the two images.
US09820797B2 Cryosurgery system
A cryosurgery system for application of medical-grade liquid nitrogen to a treatment area via a small, low pressure, open tipped catheter. The system includes a console, including a touch panel computer, a cryogen module, a suction module and an electronics module, and a disposable spray kit. Features include optional low cryogen flow setting to reduce the cryogen flow rate by 50%, improved cryogen flow consistency reducing pressure pulses and peaks, an integrated suction pump for improved consistency and self-checks, specified vent tube areas and corresponding maximum expected pressures during cryospray procedure; optional pressure sensing capability to monitor pressure during a treatment, and novel catheter designs of multilayer and flexible construction providing a variety of spray patterns.
US09820795B2 Cryocatheter with single phase coolant fluid cooled thermoelectric module and cerebral medical procedures employing local ice ball
Cryocatheter including an elongated flexible catheter member having a short rigid catheter tip for introduction into a therapy site and a heat exchange arrangement for freezing the catheter tip to a cryo-temperature from between about −15° C. to about −30° C. for freezing human tissue at the therapy site. Cerebral medical procedures include inter alia employing a local ice ball for sealing a bleeding rupture in an arterial wall in the case of a stroke hemorrhage, employing a local ice ball for mapping electrical disorder foci in a brain, for example, epileptic foci, and the like.
US09820789B2 Systems and methods for the fixation or fusion of bone
A stem-like bone fixation device allows for bony in-growth on its surface and across fracture fragments or between bones that are to be fused.
US09820788B2 Bone fusion system
A method and system for performing bone fusion and/or securing one or more bones, such as adjacent vertebra, are disclosed. The screws include a threaded tip connected to a main shaft and a threaded outer sleeve that rotates relative to the outer shaft until locked down. Independent rotation of the threaded outer sleeve relative to the threaded distal tip allows compression or distraction to modify the gap between the vertebral bodies. The screws are passed from the inferior to superior vertebra or superior to inferior, for example, through a trans-pedicular route to avoid neurological compromise. At the same time, the path of screw insertion is oriented to reach superior or inferior vertebra. An intervertebral cage of the system is configured for lateral expansion from a nearly straight configuration to form a large footprint in the disc space. The screws and cage may be combined for improved fixation with minimal invasiveness.
US09820785B2 Bone affixing apparatus and method for using thereof
A bone affixing apparatus including a substantially hollowed shaft for being inserted into the bone, at least one projectable element disposed within the shaft, and a first mechanism for projecting prongs of the at least one projectable element out of shaft into a tissue of the bone, thereby eliminating breaching the bone from the outside of the bone.
US09820784B2 Apparatus for spinal fixation and methods of use
In some embodiments, a method comprises forming a lumen in a first bone portion and forming a lumen in a second bone portion. The method further includes inserting a portion of a flexible fastening band through the lumen in the first bone portion and through the lumen in the second bone portion, and inserting the portion of the flexible fastening band into a fastener mechanism monolithically formed with the flexible fastening band. The method further includes advancing the portion of the flexible fastening band through the fastener mechanism until the first bone portion and the second bone portion are stabilized.
US09820783B2 Integrated electromagnetic implant guidance systems and methods of use for sacroiliac joint fusion
A system for fixating a dysfunctional sacroiliac joint for SI joint fusion, the system including a sacroiliac joint implant, a sacroiliac joint screw or rod and a delivery tool configured for approaching a sacroiliac joint. The system may include an implant having a porous 3D matrix structure and may be manufactured by laser or electron beam additive manufacturing. The delivery tool may include a radiolucent material. The SI fusion system may further include custom sacroiliac joint implants, anchors, alignment tools or targeting arms manufactured for a particular patient. Pre-surgical imaging studies, including 3D rendering, and their interpretation may assist in planning desired trajectories, anchor dimensions and implant dimensions and may provide details specific to the manufacture of particular sacroiliac joint tools or implants and their implantation into the sacroiliac joint. The system may be configured for use with surgical robots and may include an integrated nerve monitoring and stimulation system.
US09820782B2 Bottom loaded pedicle screw
A pedicle screw includes a tulip head, a rod seat, a screw shank, and a retainer collar. The tulip head has an upper opening disposed in a top end of the tulip head and a lower opening disposed in a bottom end of the tulip head opposite the upper opening. The upper and lower openings form a single cavity extending through the tulip head from a top end to the bottom end. The rod seat is disposed within the cavity of the tulip head and engages a stop extending inwardly from an interior wall of the cavity. The screw shank has a thread disposed along a length of the screw shank and a connector positioned at an upper end. The retainer collar has a pass through aperture, an expansion slit, and is disposed about the connector of the screw shank. Other embodiments are described and claimed.
US09820781B2 Uniplanar bone anchor system
The present teachings provide one or more surgical implements for repairing damaged tissue, such as in the case of a spinal fixation procedure. A uniplanar bone anchor system for a fixation procedure is provided. The system can include a bone fastener including a head with a bearing surface and a shaft adapted to engage an anatomy. The system can also include a saddle, which can include a first bore formed about a longitudinal axis that receives the bone fastener and a coupling bore defined transverse to the longitudinal axis. The system can also include a coupling system, which can have a second bearing surface. The coupling system can be received through the coupling bore such that the second bearing surface of the coupling system can contact the bearing surface to permit the bone fastener to move in only one plane.
US09820778B2 Pop on spreader system
A post that is configured to be coupled to a head of a bone fixation element that is attached to a bone part can include a post body that is elongate along a first direction and defines a proximal end and a distal end that is spaced from the proximal end along the first direction. The post body can include an internal surface that defines a socket at the distal end. The socket can be configured to receive the head of the bone fixation element. The post can further include a locking member that is disposed within the socket such that when the socket receives the head of the bone fixation element the locking member couples the post body to the bone fixation element. The post body is polyaxially pivotable relative to the head when the post body is coupled to the bone fixation element.
US09820776B2 Ratcheting strut
A ratcheting strut comprising: (a) a ratchet box including a through passage; (b) a first tube sized to extend at least partially through the passage, the first tube including teeth that engage corresponding teeth of the ratchet box; (c) a second tube mounted to the ratchet box in parallel with the first tube, the second tube operatively coupled to a second fixation adapter; and, (d) a threaded rod operatively coupled to a nut and a first fixation adapter, the threaded rod repositionably mounted to the first tube, where the nut is operatively coupled and repositionable with respect to the first tube.
US09820773B2 Emergency foreign object extracting device for choking victims
A rescue device for a choking victim and a method of rescuing a choking victim is provided. The device includes a first tube that is configured to be inserted into the victim's mouth so as to assist in dislodging a foreign object in the victim's windpipe by creating a low-pressure environment within the victim's mouth. The device further includes a second tube that is configured to allow a rescuer to create the low-pressure environment in the victim's mouth by sucking on a second tube of the device. A filter is positioned between the first and second tubes to reduce sanitary concerns and to prevent the foreign object from becoming lodged in the rescuer's windpipe.
US09820772B2 Vaginal manipulator with a head extender
A vaginal manipulator includes a head, a tissue index, a door, and a head extender. The head has a first end connected to a shaft and a distal end opposite of the first end. The tissue index is disposed laterally across the head and is adapted to slide in a longitudinal direction between the first end and the distal end of the head. The door has a pivot portion attached to a distal portion of the head and a free portion that is movable away from the head. The head extender includes a post that is insertable into an orifice formed in the distal end of the head.
US09820771B2 Apparatus and method for minimally invasive surgery
A single body port or body flange access device and method for performing laparoscopic surgery are disclosed. The device comprises a plurality of crisscrossing conduits through which surgical instruments may be inserted. The instruments are manipulated so that triangulation is obtained using one patient body flange while standard surgical procedures are performed on the patient.
US09820770B2 Method and system for reversibly controlled drilling of luminal occlusions
A luminal drilling system includes a drilling device and a control unit. The drilling device includes an elongate member having a drive shaft with a drill tip. The control unit includes a motor connectable to the drive shaft and control circuitry which rotationally oscillates the drive shaft with the direction of rotation automatically reversing whenever the load on the motor and/or drive shaft exceeds a threshold value.
US09820767B2 Endoscopic suture cutter
A rotatable jaw device for use with an endoscope. The device includes a fork, and two jaws pivotally mounted to the fork. The jaws are movable between a predetermined closed position and a predetermined open position. At least one jaw has at least one protrusion on a surface of the jaw. The at least one protrusion prohibits movement of the two jaws in the opening direction beyond the predetermined open position.
US09820765B2 Surgical instrument with stamped double-flange jaws
A surgical instrument includes an elongated shaft having a distal portion and a proximal portion coupled to a housing. An inner shaft member extends at least partially through the elongated shaft and is selectively movable in a longitudinal direction. An end effector is supported by the distal portion of the elongated shaft. The end effector includes upper and lower jaw members pivotally coupled to the distal portion of the elongated shaft about a pivot axis and including a pair of laterally spaced flanges. The pairs of flanges of the jaw members are arranged in an offset configuration such that one flange of the upper jaw member is positioned on a laterally exterior side of a corresponding flange of the lower jaw member, and the other flange of the upper jaw member is positioned on a laterally interior side of the other flange of the lower jaw member.
US09820763B2 Lithotripsy apparatus using a flexible endoscope
An apparatus and method are presented comprising an endoscope including a flexible shaft which has an active deflection section at a distal tip, a handle connected to a proximal end of the flexible shaft, a platform mounted to a top portion of the handle and oriented substantially in line with the longitudinal axis of the proximal end of a straight portion of the flexible shaft to provide a substantially straight entry into a working channel of the flexible shaft for an output accessory, a stone retrieval device insertable into the proximal end of the working channel of the endoscope, a lithotripsy shaft including one or more guide features at a distal end of the lithotripsy shaft to facilitate passage of wires or filaments of the stone retrieval device there through, and a lithotripsy shaft driver attached to the platform for driving the lithotripsy shaft under power.
US09820761B2 Rapid aspiration thrombectomy system and method
An intravascular access system for facilitation of intraluminal medical procedures within the neurovasculature through an access sheath. The system includes an aspiration or support catheter having a flexible, distal luminal portion having an inner diameter defining a lumen extending between a proximal opening at a proximal end of the luminal portion and a distal opening at a distal end of the luminal portion. The catheter has a rigid spine coupled to at least the proximal end of the luminal portion and extending proximally therefrom. The system includes a dilator having a flexible, distal dilator portion sized to be received within the lumen of the luminal portion. Associated systems, devices, and methods of use are also described.
US09820760B2 Aiming device for distal locking of intramedullary nails and methods of use
An aiming device system that is configured to align at least one bone anchor guide to a first distal hole of an intramedullary nail can include an aiming arm that is configured to be operatively coupled to the intramedullary nail and an aiming guide. The aiming arm can define a sliding support that is elongate along a first direction. The aiming guide can include a guide body that defines at least a first bone anchor guide. The aiming guide is attached to the aiming arm such that the aiming guide is selectably movable along the sliding support, and selectably rotatable relative to the aiming arm. When the first bone anchor guide is retaining the guide sleeve, at least one of the selectable movement and selectable rotation of the guide body at least partially aligns the first bone anchor guide with the first distal hole of the intramedullary nail.
US09820757B2 Instrument for reshaping the head of a femur
An orthopedic cutting tool for reshaping the end of a femur is described. The cutting tool comprises three separate cutting blades that are positioned within different locations within a housing to reshape the end of the femur to thus receive a femur head prosthetic. The cutting tool forms the reshaped femur end in one cutting motion.
US09820755B2 Sternal closure cerclage, plate implant and instrumentation
A system including a bone punch tool and a needle guide. The bone punch tool can include a support arm having a support arm proximal portion and a support arm distal portion, a pivot arm having a pivot arm proximal portion and a pivot arm distal portion, and an arcuate punch configured to punch through bone. The pivot arm distal portion can be pivotably coupled to the support arm distal portion, such that the pivot arm proximal portion is configured to be moved away from the support arm proximal portion to extend the arcuate punch into a punch position to punch an arcuate hole through bone. The needle guide can be configured to guide a needle through the arcuate hole.
US09820753B2 Surgical sagittal saw blade with a static bar, a pivoting blade head, drive rods that pivot the blade head and fingers that connect the drive rods to the blade head, the fingers being seated in the static bar
A surgical sagittal saw blade with a static blade bar, an oscillating blade head and at least one drive rod disposed in the blade bar that pivots the blade head. The blade bar is formed with an opening located proximal to the distal end of the blade. A finger connected to a distal end of the drive rod is located above the drive rod so as to be seated in the opening in the blade bar. The finger extends forward of the drive rod over a base section of the blade head. A pin that extends from the finger pivotally connects the blade head to the finger and, by extension, to the drive rod.
US09820751B2 Surgical drape configured for peripherally inserted central catheter procedures
A medical drape (100) includes an upper portion (101) and a lower portion (102). The upper portion (101) can be pellucid, while the lower portion (102) can be opaque. To facilitate central catheter insertion, the upper portion (101) can define one or more apertures (104,105) through which a central line may be inserted. A tourniquet (401) may be integrated with the drape, as can one or more tool-less removal features (108,109).
US09820749B2 Intra-abdominal pressure to promote hemostasis and survival
Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.
US09820748B2 Insertion aid with interference fit
The present disclosure relates to an insertion device including a shaft with a head supported on a distal end thereof. The shaft includes a proximal end with an engagement member that is configured to frictionally engage a distal end of a surgical fastening apparatus such that an interference fit is created therebetween to facilitate selective detachment of the insertion device from the surgical fastening apparatus. The head has an atraumatic configuration, and is dimensioned to be received in a body orifice.
US09820746B2 System and method for scaffolding anastomoses
Embodiments of the invention provide systems and methods for using a tissue scaffold to facilitate healing of an anastomosis. One embodiment provides a tissue scaffold for placement at an anastomotic site within a body lumen comprising a radially expandable scaffold structure having lateral and mid portions, at least one retention element coupled to each lateral portion and a barrier layer. The retention element engages a luminal wall when the scaffold structure is expanded to retain the structure and exert a compressive force on the anastomosis. The mid portion has a greater radial stiffness than the lateral portions such that when the structure is expanded, the lateral portions engage tissue prior to the mid portion. The barrier layer is configured to engage a luminal wall when the structure is expanded to provide a fluidic seal at the anastomosis. The barrier layer may also include releasable biological agents to promote anastomotic healing.
US09820744B2 Anastomosis clipping tool with half-loop clip
A tool to fasten tissue or to fasten a prosthetic to tissue includes a gripper to hold one or more tissue portions, a needle, an actuator to drive the needle, a fastener cartridge to store one or more tissue fasteners, a holder cartridge to store one or more holders, and a holder applier to secure one of the holders on one of the fasteners. The actuator drives the needle and the needle pulls a first fastener from the fastener cartridge. The actuator drives the needle through the one or more tissue portions held by the gripper to form a hole in the tissue portions. The needle pulls a leading portion of the first fastener through the hole without a trailing portion of the first fastener being pulled through the hole. The holder applier secures a first holder from the holder cartridge onto the leading portion of the first fastener.
US09820743B2 Sutureless vascular anastomosis connection
Techniques for sutureless vascular anastomosis are described, including an incision seal including a base configured to partially house an outer surface of a main vessel, the base being formed using a material that is configured to be penetrated by a barb disposed on a connector the main vessel being secured to the base when the base is at least partially pierced by the barb, an upper lumen configured to guide a graft vessel, and a housing opening configured to receive the graft vessel.
US09820736B1 Laparoscopic suture loop maker
There are many methods of tying a knot in a surgical suture. One method is to form a loop in the suture and then pull the other end of the suture through the loop. To do this laparoscopically is the object of the present invention. The finger loop handles of two small diameter laparoscopic graspers are sacrificed, and their shafts are then placed within a single common sheath, using also a single common in-line handle. The jaws of the graspers are operated by spring loaded push knobs on the handle. A loop is formed by grasping the same suture at two points a short distance apart simultaneously with the two graspers, and then bringing them together. The present invention is capable of doing this by virtue of one of the two graspers being slide-able, extendable and retractable.
US09820734B2 Device for cutting suture from a distance
The present disclosure provides a cutting assembly for cutting an object, such as a suture, within the body of a patient. The cutting assembly includes a housing, a proximal cutting element, a distal cutting element, and an actuating member. Both the proximal and distal cutting elements have a cutting surface or blade. The blades face each other within the housing and actuate towards each other to cut the suture. The housing further includes a plurality of slots that house the blades and maintain them in the orientation desired for cutting. The housing further includes openings to guide the suture through the cutting assembly. The cutting assembly provides sufficient flexibility to be oriented at the suture location, but maintains its rigidity to effectuate a sufficient, clean cut.
US09820729B2 Surgical access system and related methods
A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.
US09820728B2 Apparatus and methods for sealing a vascular puncture
A sealant for sealing a puncture through tissue includes a first section, e.g., formed from freeze-dried hydrogel, and a second section extending from the distal end. The second section may be formed from PEG-precursors including PEG-ester and PEG-amine, e.g., in an equivalent ratio of active group sites of PEG-ester/PEG-amine greater than one-to-one, e.g., such that excess esters may provide faster activation upon contact with physiological fluids and enhance adhesion of the sealant within a puncture. At least some of the precursors remain in an unreactive state until exposed to an aqueous physiological environment, e.g., within a puncture, whereupon the precursors undergo in-situ cross-linking to provide adhesion to tissue adjacent the puncture. For example, the PEG-amine precursors may include the free amine form and the salt form. The free amine form at least partially cross-links with the PEG-ester and the salt form remains in the unreactive state in the sealant before introduction into the puncture.
US09820727B2 Single piece, dual component sealing pad and methods
A tissue puncture closure device includes a carrier tube and a sealing plug. The carrier tube includes a distal end configured for insertion into the tissue puncture. The sealing plug is positioned in the carrier tube and arranged for ejection from the distal end of the carrier tube into the tissue puncture. The sealing plug includes a first collagen portion having a first cross-linked chemical structure, and a second collagen portion positioned proximal of the first collagen portion in the carrier tube. The second collagen portion has a second cross-linked chemical structure that is different from the first cross-linked chemical structure.
US09820726B2 Polymer membrane locator with built-in stress relief structure
A tissue puncture locator device that includes an expandable member, a deformable membrane, and an actuator. The expandable member is movable between an unexpanded position and an expanded position. The deformable membrane extends around at least a portion of the expandable member. The membrane has a stress relief portion. The actuator is operable to move the expandable member between the unexpanded and expanded positions.
US09820723B2 Positioning guide apparatus with friction lock
The present invention presents an apparatus and methods to guide insertion of invasive devices to a tissue target of a living body. The apparatus comprises a positioning guide control assembly and a positioning guide assembly that is operably detachable from the control assembly, and rotationally adjustable and lockable. The positioning guide control assembly releasably houses a ultrasound transducer head and measures an insertion length and an insertion angle of an invasive device placed in the positioning guide assembly to reach the tissue target.