Document Document Title
US09593677B1 Electric hydraulic motor system for vehicles
An electric hydraulic motor system for vehicles features an electric motor and an electric generator operatively connected to a battery of a vehicle and hydrogen fuel cell. The system features a fuel engine hydraulic pump operatively connected to a standard fuel engine of the vehicle. The system features a hydraulic reservoir operatively connected to the fuel engine hydraulic pump. The system features a first hydraulic pump operatively connected to each the electric motor and the hydraulic reservoir. The system features a first hydraulic motor operatively connected to each the hydraulic reservoir, and wheels of the vehicle. The system features a second hydraulic motor operatively connected to each the electric generator and the hydraulic reservoir. The system features a second hydraulic pump operatively connected to each the wheels of the vehicle and the hydraulic reservoir.
US09593676B2 Rectangular pump attachment interface providing a portable fixed link between a pump line coupled to a mobile tank and a line disposed in a reservoir
A portable and relocateable pump attachment interface provides a fixed link between a first line in communication with a fluid reservoir, and a second line in communication with a mobile storage tank via a pump of a pump truck. The interface includes an interface body that supports a fixed conduit entirely above ground. The front end of the conduit is for coupling to the first line, and the back end of the conduit is for coupling to the second line. The interface body has a fitting access space and a spill containment catch basin disposed under the fitting access space, and the second end of the conduit is located within the fitting access space and over the spill containment basin to catch any spillage from the second line when it is coupled to and uncoupled from the conduit. The interface body can be a concrete block, or be molded plastic filled with sand or water and is massive enough to substantially isolate line one from line 2. A metal conduit cover controls access to the front end of the conduit by enclosing the fixture access space.
US09593669B2 Hydraulic transmission methods and apparatus for wind turbines
A hydraulic transmission for a wind turbine that includes a rotor, one or more blades mounted to the rotor, a hydraulic pump mechanically connected to the rotor, and a hydraulic motor. The hydraulic pump and the hydraulic motor are connected to one another by a high pressure circuit. The hydraulic pump maybe a variable displacement hydraulic pump and the hydraulic motor may include a variable displacement hydraulic motor. The wind turbine, including the rotor, the blades of the rotor, the hydraulic pump, and the hydraulic motor may be controlled according to different approaches.
US09593668B2 Methods and systems for reducing amplitude modulation in wind turbines
A wind turbine system is presented. The wind turbine system includes a rotor comprising a plurality of blades and a hub, and a turbine controller configured to reduce an abnormal amplitude modulation of the wind turbine by adjusting pitch angles of the plurality of blades during a rotation of the rotor based upon aerodynamic loads acting on the rotor.
US09593667B2 Wind turbine generator
A wind turbine generator is disclosed herein. In a described embodiment, the wind turbine generator comprises an electrical generator 101 configured to generate AC signals, a plurality of power converters 110,112,111 operated by a gating signal with each power converter configured to convert the AC signals from the electrical generator 101 into fixed frequency AC signals. The wind turbine generator further comprises a controller configured to enter a fault mode when a grid voltage falls outside an acceptable threshold, and during the fault mode the controller is configured to provide a reactive current reference dependant on a grid voltage distant from the wind turbine generator. A method of controlling a wind turbine generator is also disclosed.
US09593665B2 Hydro-kinetic transport wheel
A turbine wheel designed to exploit the head of watercourses that operates partially or totally submerge with means for a wheel mounting enclosure having a cavity equal to 50% of the height of the runner where the runner rest exposing the upper end into the bed of the flowing body of water and said cavity mask the runner from the water incident flow allowing the wheel to perform fully submerged gaining its power and momentum through water current acting upon an array of multifaceted cells attached to spokes radiating from a central circular body member to the outer perimeter of a wheel, distributed wall-to-wall occupying the peripheral annulus of the water stream always presenting a new facet as it rotate around it axis covering 180 degrees of the water incident flow. The outside surface of the runner attaches to a multiplicity of similar runners by means of mechanical devices and to the central circular body member. The plurality of cells ensures the wheel remains constantly engage with the incoming water flow which causes it to rotate. The kinetic energy stored in the wheel while rotating is harnessed through a drive shaft connected to the central circular body member that connects to a generator placed perpendicular to the central circular body member. The apparatus can be used in multiple environments with a multiplicity of water currents able to generate electricity from the kinetic energy contained therein.
US09593663B2 Photo-ignition torch for combustion initiation and gas generation
A photo-ignition torch is provided including a light source configured to generate at least one of ultraviolet, visible, and infrared light. A photo-ignitable sub-micron particle mix is contained in capsule configured to receive the at least one of ultraviolet, visible, and infrared light generated by the light source or alternatively the photo-ignitable sub-micron particle mix is in direct contact with the light source. The exposure of the photo-ignitable sub-micron particle mix to the at least one of ultraviolet, visible, and infrared light initiates a photo-ignition process causing a release of burning byproducts of the photo-ignition process.
US09593662B2 Corona ignition device and method for producing an ignition head for a corona ignition device
The invention relates to a corona ignition device for igniting fuel in a combustion chamber of an engine by means of a corona discharge, comprising an insulator, a center electrode, which plugs into the insulator and carries an ignition head having a plurality of ignition tips, a coil, which is connected to the center electrode, and a housing, which surrounds the coil and into which the insulator plugs, wherein the ignition head has main body formed from sheet metal. In accordance with the invention, the ignition tips consist of a different material compared to the main body and are fastened to a side face of the main body. The invention also relates to an ignition head for such a corona ignition device and to a method for production thereof.
US09593661B2 Preheater assembly, a cylinder head, a piston engine, and an aircraft
A preheater assembly of a glowplug and a hollow sheath extending longitudinally from a bottom external zone to a top external zone, the sheath extending radially from an inside surface defining a cavity towards an outside surface, the glowplug being inserted in the cavity, the tip projecting from the sheath through the bottom external zone, the inside surface of the sheath presenting a second thread meshing with a first thread of the glowplug, the inside surface of the sheath presenting a first conical seat bearing against the first conical bearing surface of the glowplug, the outside surface of the bottom external zone having a third thread screwed into a cylinder head and a second bearing surface that bears against the second seat of a cylinder head.
US09593659B2 Method and system for controlling warm-up of clutch fluid in hybrid electrical vehicle
A system and a method that control warm-up of clutch fluid in a hybrid electric vehicle. The hybrid electric vehicle includes a clutch that controls power delivery between an engine and a motor and an oil pump that is operated by the motor and generates hydraulic oil pressure operating the clutch. The method includes determining, by a controller, whether delivery of power from the engine and motor in a transmission is cut and detecting temperature of the fluid using an oil temperature detector. In addition, the motor is maintained by the controller at a predetermined target speed to operate the oil pump connected to the motor when the detected temperature of the fluid is equal to or less than a predetermined temperature, wherein the predetermined target speed is a motor speed at which sufficient pressure for flowing the fluid is generated in the oil pump operating with the motor.
US09593657B2 Drive unit of fuel injection device
In a drive unit of a fuel injection device, an electric current is supplied to the fuel injection device by applying a high voltage to the fuel injection device from a high voltage source whose voltage is boosted to a voltage higher than a battery voltage at the time of opening a valve of the fuel injection device. Thereafter, the electric current supplied to the fuel injection device is lowered to a current value at which a valve element cannot be held in a valve open state by stopping the applying of the high voltage from the high voltage source. Thereafter, in a stage where a supply current is switched to a hold current, another high voltage is applied to the fuel injection device from the high voltage source.
US09593656B2 Fuel injector and calibration tube thereof
A fuel injector includes a valve member for selectively preventing and permitting flow of fuel through a valve seat by selectively engaging and disengaging the valve seat, an actuator for selectively applying a force to the valve member in order to unseat the valve member from the valve seat, and a return spring which biases the valve member into contact with the valve seat when the actuator is not applying the force to the valve member. A calibration tube is positioned within the fuel tube and holds the return spring in compression so as to set a force on the return spring to achieve a desired dynamic flow of fuel through the fuel injector. The calibration tube includes at least one protrusion extending outward therefrom such that the protrusion engages the fuel tube, thereby creating a spring fit between the calibration tube and the fuel tube.
US09593652B2 Fluid injector and method and apparatus for operating the fluid injector
A fluid injector has a longitudinal axis (L) and a valve needle (12), which is axially moveable and operable to prevent a fluid injection in a closing position and to permit the fluid injection in further positions. The fluid injector also has an armature (14) which is mechanically coupled to the valve needle (12). Furthermore, the fluid injector has a solenoid assembly (30) which has at least a first and second coil (34, 36) and which is operable to magnetically actuate the armature (14) via an electrical signal (V) applied to at least one predetermined assortment of the at least two coils (34, 36).
US09593646B2 Exhaust-gas distributor
An exhaust gas distributor is disclosed. The distributor includes a distributor housing having a first exhaust gas path fluidically connecting a first inlet opening to a first outlet opening, a second exhaust gas path fluidically connecting a second inlet opening to a second outlet opening, and a third exhaust gas path fluidically connecting the second exhaust gas path to a third outlet opening, and an adjustable control element controlling the distribution of an exhaust gas flow from the second inlet opening to the second outlet opening and the third outlet opening. The control element in its end positions cooperates with stop contours. The control element is supported in a control housing that is manufactured separately from the distributor housing and which is installed in the distributor housing.
US09593642B2 Composite cam carrier
A cam carrier assembly includes a cylinder head having valves and a camshaft having lobes. A cam carrier has a first side coupled with the cylinder head engaging around the valves and a second side with bearing surfaces supporting the camshaft. A series of apertures extend between the first and second sides for the lobes to interface with the valves. The cam carrier is made of carbon fiber composite insulating the camshaft from the cylinder head and providing substantial weight reduction to an upper section of an associated engine.
US09593637B2 Method of diagnosing injector variability in a multiple injector system
Various systems and methods are described for diagnosing injector variability in a dual fuel, multi-injector system. In one example, a single injector in one cylinder is enabled while remaining cylinders are fueled with a first fuel and subsequently, a second fuel is injected via the enabled injector into the one cylinder in a predetermined sequence and fuel rail pressure drops are measured. Further, measured pressure drop after each injection event is corrected for an increase in injector closing delay.
US09593636B2 Throttle learning control apparatus
There is obtained a throttle learning control apparatus that raises the reliability of throttle fully closed and opened learning even when a self-shutoff delay abnormality occurs and can suppress various defects that occur when a throttle fully closed learning value or a throttle fully opened learning value is not updated. After a self-shutoff delay abnormality occurs, an electronic control unit implements fully closed learning 1 and fully opened learning 1 while the engine is operated in a non-engine-stall period and implements fully closed learning 2 and fully opened learning 2 for compensating the fully closed learning 1 and fully opened learning 1. Fully closed learning is completed when the fully closed learning 1 or the fully closed learning 2 has once been implemented; similarly, fully opened learning is completed when the fully opened learning 1 or the fully opened learning 2 has once been implemented.
US09593634B2 Heat release rate waveform generating device and combustion state diagnostic system for internal combustion engine
In a diesel engine, an inside of a cylinder is divided into intra-cavity and extra-cavity regions. Ideal heat release rate waveform models, each formed of an isosceles triangle in which each oblique line gradient is a reaction rate, an area is a reaction amount and a base length is a reaction period with a reaction start temperature as a base point, are generated respectively for a vaporization reaction, low-temperature oxidation reaction, thermal decomposition reaction and high-temperature oxidation reaction of injected fuel for each region. An ideal heat release rate waveform of the reaction modes is generated by smoothing the ideal heat release rate waveform models through filtering and combining the ideal heat release rate waveforms, and is compared with an actual heat release rate waveform obtained from a detected in-cylinder pressure. A reaction mode having a deviation larger than or equal to a predetermined amount is diagnosed as being abnormal.
US09593633B1 Combustion pre-chamber and method for operating same
An internal combustion engine includes a pre-chamber assembly including a wall having an internal surface opposite an external surface, the internal surface of the wall defining a combustion pre-chamber and at least one orifice extending to an aperture through the external surface of the wall; a block having an internal surface defining a bore therein; a piston disposed within the bore and configured for reciprocal translation within the bore, the piston, the bore, and the external surface of the wall at least partly defining a main combustion chamber, and the combustion pre-chamber being in fluid communication with the main combustion chamber via the at least one orifice; an energy source operatively coupled to the combustion pre-chamber; and an exhaust gas recirculation (EGR) valve fluidly coupled to the combustion pre-chamber and an exhaust conduit of the internal combustion engine.
US09593632B2 System and method for operating an exhaust gas recirculation valve
A method of operating an Exhaust Gas Recirculation (EGR) valve of an engine is provided. The method includes monitoring an operating condition of the engine based at least on a speed of the engine and a load of the engine. The method also includes determining an amount of Carbon Monoxide (CO) in an exhaust from the engine and comparing the amount of CO with a threshold CO value. The method further includes adjusting open loop parameters of the EGR valve based on the comparison during a predetermined operating condition for the engine. The EGR valve is controlled based on the open loop parameters during switching between a closed loop control and an open loop control of the EGR valve.
US09593623B2 System and method for controlling operation of an engine
The method involves receiving a plurality of current operating parameters of an engine during operation of engine and determining at least one of a current substitution ratio and a current peak cylinder pressure based on the plurality of current operating parameters. The method also involves determining at least one of a target substitution ratio and a predefined peak cylinder pressure based on the plurality of current operating parameters and comparing at least one of the current substitution ratio with the target substitution ratio and the current peak cylinder pressure with the predefined peak cylinder pressure. The method also involves controlling a first power output from a plurality of engine cylinders and a second power output from an electric turbo-compounding system, based on the comparison of at least one of the current substitution ratio with the target substitution ratio and the current peak cylinder pressure with the predefined peak cylinder pressure.
US09593617B2 Method for diagnosing an exhaust gas catalytic converter, diagnosis device and motor vehicle having such a device
A method for diagnosing an exhaust-gas catalytic converter (28) arranged in an exhaust-gas system (20) of an internal combustion engine (12) for the catalytic conversion of at least one exhaust-gas component from the internal combustion engine (12), which has an exhaust-gas recirculation means with which a partial stream of the exhaust gas can be drawn off downstream of the catalytic converter (14) and fed into the combustion air of the internal combustion engine (12), involves determining the current raw emission (NOx—raw) of the internal combustion engine (12) in of the exhaust-gas component; measuring the current concentration of the exhaust-gas component (NOx—meas) in the exhaust gas upstream of the catalytic converter (28); and determining a diagnostic value for the catalytic converter (28) in terms of the conversion of the exhaust-gas component as a function of the modelled raw emission (NOx—raw) from the internal combustion engine (12) and the measured concentration of the exhaust-gas component (NOx—meas). The invention further relates to a diagnostic device configured to perform the method and a motor vehicle having such a device.
US09593613B2 Recessed exhaust reductant injector with cover plate
An aftertreatment system comprises a housing defining an internal volume. The housing includes an inlet, an outlet and a first sidewall. A sleeve is positioned within the internal volume and protrudes through the first sidewall. An inner shell is positioned within an inner region defined by the sleeve and defines a recess therein. The inner shell spaced apart from the sleeve so as to define a channel therebetween. A base is positioned within the recess and includes an injection port which is in communication with the internal volume. An injector is disposed on the base and is disposed completely within the recess. The injector is in fluidic communication with the internal volume via the injection port. The injector is configured to inject an exhaust reductant into the internal volume via the opening. A cover plate can be disposed over the recess and structured to prevent objects from impacting the injector.
US09593612B2 Internal combustion engine
The phenomenon of resonance in a catalyst converter due to a flow of an exhaust gas is reduced without causing problems with vehicle layout, problems with manufacturing (higher manufacturing cost), or adverse influences on other facets of performance. An internal combustion engine includes an internal combustion engine main body having a fuel chamber formed in an interior, and a catalyst converter arranged in an exhaust flow channel of the internal combustion engine main body and provided with a catalyst for purifying the exhaust gas. The exhaust flow channel, which is upstream of the catalyst of the catalyst converter, is provided with a protuberance for disturbing the flow of the exhaust gas in the exhaust flow channel to reduce pressure pulsations of the exhaust gas.
US09593611B2 Exhaust gas control apparatus for internal combustion engine
It is possible to decrease the amount of NOx emitted into the air. The amount of ammonia adsorbed on an SCR catalyst is calculated by subtracting the amount of ammonium nitrate produced on the SCR catalyst from the amount of ammonia adsorbed on the SCR catalyst at the time of starting of an internal combustion engine, and the amount of NO2 flowing into the SCR catalyst is decreased when an NOx purification rate estimated from the amount of ammonia adsorbed on the SCR catalyst is less than a threshold value compared to when the NOx purification rate is equal to or greater than the threshold value.
US09593609B2 System and method for urea decomposition to ammonia in a side stream for selective catalytic reduction
A method for reducing NOx emissions in the exhaust of a combined cycle gas turbine equipped with a heat recovery boiler and a catalyst effective for NOx reduction, wherein a slip stream of hot flowing exhaust gases is withdrawn from the primary gas flow after the catalyst at a temperature of 500° F. to 900° F. and directed through a fan to a continuous duct into which an aqueous based reagent is injected for decomposition to ammonia gas and the outlet of the continuous duct is connected to an injection grid positioned in the primary exhaust for injection of ammonia gas into the primary exhaust stream at a location upstream of the catalyst.
US09593607B2 Muffler for an exhaust system of an internal combustion engine
A muffler for an exhaust system of an internal combustion engine comprises: a casing having an inner space, an inlet pipe for sound to enter the muffler, an outlet pipe for sound to exit the muffler, and a separation wall arranged to extend from the inlet pipe to the outlet pipe and being embodied in a manner such as to define first and second acoustical ducts extending through the casing to allow sound propagating along the first acoustical duct to enter the inner space of the casing and to thereafter exit the inner space of the casing again, and to allow sound propagating along the second acoustical duct to acoustically bypass the inner space of the casing.
US09593606B2 Suppressor for gaseous fuel system
A suppressor for a gaseous fuel system is disclosed. The suppressor may include a cylindrical body having a first end opposite a second end along an axis. A vent opening may be disposed at the second end. A conduit may pass through the first end and may have an inlet disposed outside the cylindrical body and an outlet disposed inside the cylindrical body. The suppressor may include an acoustic core between the outlet of the conduit and the vent opening and configured to reduce a sound level of fluids exiting the conduit. The suppressor may include a thermal mass between the outlet of the conduit and the vent opening, wherein the thermal mass includes fluid channels and is configured to transfer heat energy to fluids exiting the conduit.
US09593603B2 Camshaft phase adjuster including a camshaft with helical grooves
A camshaft phase adjuster assembly is provided that includes at least one helical groove for adjusting a phase position between a camshaft and a drive sprocket. The camshaft phase adjuster assembly includes a camshaft including at least one helical groove extending between a bore and a radially outer surface of a sprocket support portion, and the helical groove includes circumferentially offset first and second ends. A drive sprocket includes at least one axially extending drive sprocket groove on a radially inner surface of the drive sprocket arranged facing the at least one helical groove. An actuator selectively moves an actuator pin axially such that a radially extending rotation pin slides within the helical groove and the drive sprocket groove from a first phase position to a second phase position.
US09593600B2 Hybrid supercritical carbon dioxide geothermal systems
Provided herein are geothermal power generating systems utilizing supercritical carbon dioxide as a working fluid and superheating the extracted the emitted carbon dioxide utilizing external combustion of the hydrocarbons concurrently extracted with the emitted carbon dioxide to increase enthalpy and thermodynamic cycle efficiency. Methods for producing power are also provided.
US09593597B2 System and method of waste heat recovery
A novel Rankine cycle system configured to convert waste heat into mechanical and/or electrical energy is provided. The system provided by the present invention comprises a novel configuration of the components of a conventional Rankine cycle system; conduits, ducts, heaters, expanders, heat exchangers, condensers and pumps to provide more efficient energy recovery from a waste heat source. In one aspect, the Rankine cycle system is configured such that three distinct condensed working fluid streams are employed at various stages in the waste heat recovery cycle. A first condensed working fluid stream is vaporized by an expanded first vaporized working fluid stream, a second condensed working fluid stream absorbs heat from an expanded second vaporized working fluid stream, and a third condensed working fluid stream removes heat directly from a waste heat-containing stream. The Rankine cycle system is adapted for the use of supercritical carbon dioxide as the working fluid.
US09593595B2 Method of remanufacturing a machine component
A method is provided for remanufacturing a machine component having multiple holes. The holes are provided to match in alignment with corresponding holes of an adjacent component in a machine assembly. First and second sets of holes are selected from the holes of the machine component on the basis of being located within first and second limits of positional tolerance with respect to corresponding holes of the adjacent component. Each hole from the first set of holes is bored to define openings in axial alignment with holes of the adjacent component. Each hole from the second set of holes is bored to an enlarged diameter and then plugged with a deformable insert. Each of these inserts is then drilled to define openings in axial alignment with holes of the adjacent component.
US09593594B2 Method and apparatus for decongealing a lubricating fluid in a heat exchanger apparatus
A decongealing channel for use in a heat exchanger apparatus, including a supersaturated solution contained therein and an actuation component in fluid communication with a lubricating fluid coupled to the decongealing channel. The actuation component is responsive to a change in pressure exerted thereon by the lubricating fluid so as to actuate an exothermic response in the supersaturated solution. The heat exchanger apparatus is disposed in a bypass fan duct of an aircraft engine. The heat exchanger apparatus including a manifold portion, one or more flow through openings extending therethrough the manifold portion to define one or more flow through channels having contained therein the lubricating fluid. In addition, the manifold portion including one or more additional openings extending therethrough to define one or more decongealing channels. Further disclosed is an engine including the heat exchanger apparatus and a method of decongealing a lubricating fluid in the heat exchanger apparatus.
US09593585B2 Seal assembly for a gap between outlet portions of adjacent transition ducts in a gas turbine engine
A seal assembly for sealing a circumferential leakage gap between outlet portions of first and second adjacent transition ducts in a gas turbine engine includes a first seal member affixed to the outlet portion of the first transition duct and a second seal member movable with respect to the first seal member. The second seal member is positionable in a non-sealing first position and a sealing second position. While in the first position, the second seal member is circumferentially spaced from the outlet portion of the second transition duct. While in the second position, the second seal member extends across the leakage gap and creates a seal with the outlet portion of the second transition duct to substantially prevent leakage through the leakage gap.
US09593583B2 Nickel-base superalloy
A nickel-base superalloy for turbine vanes or turbine blades is provided. The nickel-base superalloy has in wt %: C: equal to or greater 0.1; Si:
US09593581B2 Combined sealing and balancing arrangement for a turbine disc
A turbine disc for a turbine is provided with a first protrusion and a second protrusion. The first protrusion and the second protrusion are formed in such a way that a balancing weight is coupleable between the first protrusion and the second protrusion. The first protrusion has a sealing section that is capable of sealing a fluid passage between the turbine disc and a further turbine part of the turbine.
US09593578B2 Compressed gas motor and lavage system
A compressed-gas motor has a cylindrical inner chamber closed gas-tight at a first base surface, and a piston arranged so as to be movable along the cylinder axis in the cylindrical inner chamber. A first opening feeds a compressed gas into the inner chamber, and a second opening discharges a gas from inside the inner chamber. The openings are arranged in the cylinder casing of the cylindrical inner chamber, wherein the first opening is arranged between the second opening and the closed first base surface. The first opening is closable by a first piston part and the second opening by a second piston part. The compressed-gas motor has a resetting device which exerts a force on the piston in the direction of the first base surface of the cylindrical inner chamber if the second piston part does not completely close the second opening.
US09593574B2 Well completion sliding sleeve valve based sampling system and method
A well completion system includes tubing, and packers that seal the annulus of the well outside the tubing. The packers are spaced to define voids in the annulus that are substantially free from hydrostatic pressure. Also included are hollow sleeve valves having upper and lower sealing elements, and that have closed and open positions. Each sleeve valve is positioned within the tubing at a depth corresponding to a void in the annulus. Ports extend through the sleeve valve and tubing, so that when the sleeve valve is closed, the port is closed, and when the sleeve valve is open, the port is open. Also included is a sampling tool having top and bottom sealing elements, the bottom sealing element for engaging the lower sealing element of a sleeve valve, and the top sealing element for engaging the upper sealing element of the sleeve valve when the sleeve valve is open.
US09593567B2 Automated drilling system
A drilling system comprises a drilling parameter sensor in communication with a sensor application 22 that generates processed data from raw data that is received from the drilling parameter sensor. A process application 24 is in communication with the sensor application 22 and generates an instruction based on the processed data. A priority controller is in communication with the process application 24 and evaluates the instruction for release to an equipment controller 14 that then issues the instruction to one or more drilling components.
US09593566B2 Semi-autonomous drilling control
A method of facilitating a drilling operation includes: receiving a current set point for a drilling operation, the current set point indicating a value of an operational parameter at which the drilling operation is being performed; receiving a global limit indicating at least one of a maximum and a minimum value of the operational parameter that is permitted to be applied for the drilling operation; defining a local limit for the operational parameter, the local limit indicating at least one of a local maximum value and a local minimum value of the operational parameter; receiving a parameter change value, the parameter change value indicating a proposed change to the operational parameter from the current set point; and selecting a level of automation by which the operational parameter can be adjusted, the level of automation based on a comparison of the parameter change value and the local limit.
US09593564B2 Processing hydrocarbons
Systems and methods that include providing, e.g., obtaining or preparing, a material that includes a hydrocarbon carried by an inorganic substrate, and exposing the material to a plurality of energetic particles, such as accelerated charged particles, such as electrons or ions.
US09593563B2 Method and apparatus for generating steam for the recovery of hydrocarbon
The instant disclosure provides a method of generating steam for the recovery of hydrocarbon from a hydrocarbon producing system including (i) generating supercritical steam from water; (ii) converting the supercritical steam to a subcritical steam; and (iii) injecting the subcritical steam into the system.
US09593562B2 Downhole fuel cell with steam adsorption and pressure compensation
A fuel cell for use in downhole applications stores steam created by the chemical reaction in a desiccant like Zeolite. The fuel cell also uses ambient hydrostatic pressure to increase cell voltage and power-density.
US09593561B2 Hanger and penetrator for through tubing ESP deployment with a vertical production tree
A hanger assembly for use in a vertical production tree that includes an annular piping spool member having a side opening, and a hanger having an outer surface profiled to selectively land in the piping spool member and a side opening registered with the side opening of the piping spool member. The hanger assembly also includes a vertical penetrator having an end selectively connected to a submersible device and an opposing end inserted into the hanger, and that is in communication with the side openings.
US09593555B2 Auto-filling of a tubular string in a subterranean well
A system can include at least one check valve which prevents outward flow through a wall of a tubular string in a well, the wall surrounding a longitudinally extending flow passage of the tubular string. The check valve can include a ball or poppet which sealingly engages a seat. Another system can include multiple redundant check valves which prevent outward flow through a wall of a tubular string in a well. A well tool can include multiple redundant check valves which prevent flow in one direction through the wall, and which permit flow in an opposite direction through the wall. Each of the multiple redundant check valves can include a ball or poppet which sealingly engages a seat.
US09593552B2 Cementing a wellbore using cementing material encapsulated in a shell
A system for cementing a wellbore penetrating an earth formation into which a pipe extends. A cement material is positioned in the space between the wellbore and the pipe by circulated capsules containing the cement material through the pipe into the space between the wellbore and the pipe. The capsules contain the cementing material encapsulated in a shell. The capsules are added to a fluid and the fluid with capsules is circulated through the pipe into the space between the wellbore and the pipe. The shell is breached once the capsules contain the cementing material are in position in the space between the wellbore and the pipe.
US09593548B2 System and method for safely conducting explosive operations in a formation
Method and system that permits explosive operations to be conducted concurrently with drilling and other wellsite operations involving an electrical top drive mechanism or other components that utilize electricity are disclosed. A platform is placed at a location where subterranean operations are to be performed. A first well bore is drilled in a formation using drilling equipment on the platform by activating a top drive. Concurrently with drilling the first well bore, a perforating operation is performed in a second well bore extending from the platform. The perforating operation is performed using a perforating gun that comprises at least one of an electric isolator and an explosive isolator. The perforating gun is activated when the perforating gun reaches a safe depth.
US09593544B2 Clamp assembly
A clamp assembly which includes two spaced apart jaw systems each of which has two sets of spaced apart relatively pivotal grip formations, wherein the jaw systems are relatively pivotally movable to position the four sets of grip formations at spaced apart locations on a circumference of a circle, wherein the size of the circumference is determined at least by the extent of relative pivotal movement of the jaw systems.
US09593539B2 Methods of forming downhole tools having features for reducing balling
Downhole tools are provided with a topographical pattern, and anti-balling material is provided over the topographical pattern. The topographical pattern may be defined by at least one of a plurality of recesses extending into a surface of a body of the tool and a plurality of protrusions protruding from the surface. Downhole tools include an insert disposed within a recess in a body, and the insert comprises an anti-balling material having a composition selected to reduce accumulation of formation cuttings on the tools when the tools are used to form or service a wellbore. Downhole tools include anti-balling material disposed over a porous mass provided over the surfaces of the tools. Methods of forming downhole tools include providing anti-balling material over features on and/or in a surface of a body of a tool. Methods of repairing downhole tools include removing an insert therefrom and disposing a replacement insert therein.
US09593531B2 Ladder securing apparatus, ladders incorporating same and related methods
A ladder is provided having a securing apparatus for securing the ladder to a horizontally extending support structure (e.g., a utility cable), a vertically extending support structure (e.g., a utility pole) or both. In accordance with one embodiment, the securing apparatus includes a pair of spaced apart engagement mechanisms, wherein each engagement mechanism is pivotally coupled with an associated rail of the ladder. Each engagement mechanism includes a frame member, an engagement member pivotally coupled with the frame member and a pole grasping structure coupled with the frame member. In one embodiment, each engagement member is configured to rotate from a first position, wherein an open gate is formed between the engagement member and its associated frame member, to a closed position.
US09593525B1 Articulated overhead door systems and methods
An articulated door system includes one or more door sections; a lifting block associated with a lower door section of the one or more door sections; a frame supporting the one or more door sections and engaging the lifting block; and a lead screw system including a rotatable lead screw that is configured to engage the lifting block and lift the lower door section up and down based on rotation of the lead screw.
US09593524B2 Window mounting system
The invention relates to a window mounting system comprising: a building facade having an interior face and an exterior face and comprising a window opening; and a window mounting collar formed from rigid thermal insulating material, the mounting collar having at least one inside face, at least one outside face, a first open end and a second open end; wherein the window mounting collar is affixed to the exterior face of the building facade so as to surround the window opening and extend outwards from the exterior face of the facade, such that the first end of the mounting collar is proximal to the building facade and the second end of the mounting collar is distal from the building facade; wherein the system further comprises a window frame arranged in the mounting collar such that the window frame is separated from the plane of the exterior face of the building facade by at least 10 mm.
US09593522B1 System including a hand-held communication device having a motion sensor for remotely controlling the position of a door of a land vehicle and key fob for use in the system
A system for remotely controlling the position of a land vehicle door is provided. The system includes a mobile communication device supported on the vehicle for movement therewith and a hand-held communication device such as a key fob including a motion sensor operative to provide motion signals as a function of motions made by a pedestrian carrying the hand-held device. Control logic is coupled to the devices and is operative to detect a sequence of step motions made by the pedestrian carrying an authorized hand-held device when the pedestrian carrying the authorized hand-held device is located within a predetermined, short range of the mobile device and to generate a door-opening control signal based on command data contained within a command signal transmitted by the hand-held device and/or when the control logic recognizes the detected sequence of step motions as a door-opening pedestrian command.
US09593519B2 Magnetic levitation system for doors and windows
A magnetic levitation system for sliding door and window, includes at least a movable module for the lower part of the sliding door and window which includes one or more permanent magnets; several fixed modules for the lower part of the frame of the sliding door and window, which includes one or more electromagnets to produce a variable repulsive magnetic field of the magnetic field of said magnets of the movable module. It has the advantage of eliminating the friction, mechanical wear and noise associated to the sliding, allowing, when deactivated, a greater air and water tightness and terminal and acoustic insulation, allowing the electromagnetic closure or locking of the door and window, increasing the security, and as is a modular system its operation and construction are simpler and more economical.
US09593514B2 Seamless exterior handle for a vehicle door
A vehicle door includes a lock cylinder having an actuator member that is operably connected to a door latch mechanism. A door handle moves from a first or home position covering an outer end of the lock cylinder to a partially open position wherein the outer end of the lock cylinder is exposed. When the door handle is in the partially open position, a user can access the lock cylinder and insert a key into the lock cylinder to unlock the door. Thus, the lock cylinder is covered and hidden behind a portion of the door handle when the door handle is in the first position to provide an uncluttered, visually appealing appearance.
US09593513B2 Lock release apparatus
A lock release apparatus has a handle and a cable. The handle has a gripping portion and a cable receiving portion. The cable, which is capable of a path of movement over the cable receiving portion, has a cable end which is retained within the handle through an opening of the cable receiving portion. The cable receiving portion includes at least one retention portion which is deflectable in response to compressive force and a blocking portion that blocks engagement of the cable with the at least one retention portion. In another aspect, the cable receiving portion includes at least one retention portion, without a blocking portion, where the at least one retention portion is located out of the path of movement of the cable with respect to the handle.
US09593508B2 Craft dome
The quickly erectable dome shelter includes an extendible perimeter truss assembly with link members connected between adjacent legs, a central truss assembly of link members, and a roof framework, including pairs of curved upper and lower peak truss members, that is movable between a lowered, collapsed configuration and a raised, upwardly arching position. The shelter also includes telescoping peak pole members coupled to the central truss assembly of link members and the roof framework, and may also include telescoping peak truss brace members connected between a peak truss member and a link member of the perimeter assembly of link members.
US09593506B2 Method of modular pole construction and modular pole assembly
A method of modular pole construction an elongate modular pole structure is disclosed. A first step of the method involves providing hollow tapered pole section modules, each module having a first open end and an opposed second open end. A cross-section of the second end is less than a cross-section of the first end. The modules are stacked to form an elongated modular pole structure of a selected length by mating the second end of a first module with the first end of a second module. The first and second modules may have different structural properties, such that poles having desired structural properties can be constructed by selectively combining modules having differing structural properties.
US09593486B2 Structural component
A structural component for use in building construction including a first and second support material member, an insulating material, and a first securing member. The first support material member may have a first length, a first side, and an opposing second side. The second support material member may have a second length, a first side, and an opposing second side. The second support material member may oppose the first support material member. The insulating material may be disposed between the first support material member and the second support material member. The first securing member may be adapted to secure the first support material member to the second support material member.
US09593482B2 Bar of a support structure for a false ceiling and working process for working the bar
A bar of a support structure for a false ceiling is described. The bar has an elongated shape along a longitudinal direction and includes at least two sheet metal portions located side by side or overlapped, in contact or adherent, with each other along said longitudinal direction, or short side direction. In the bar a transverse direction, or short-side direction, extending transverse to, or intersecting, said longitudinal direction is defined. At least one of the sheet metal portions has cuts defining partially cut parts, wherein a partially cut part of said at least one of the sheet metal portions protrudes towards the other of said sheet metal portions in a thickness direction so as to determine an interference of parts in the thickness direction. The cuts are arranged, are directed, or extend along said transverse direction and the partially cut parts have, when viewed in perspective, an at least partially curvilinear or concave profile.
US09593481B2 Wall-mounted devices, systems, and methods for selectively positioning objects
Implementations of the present invention relate to systems, methods, and apparatus for positioning and/or selectively repositioning one or more objects within an individual space. More specifically, a functional wall module can at least partially define the individual space. Furthermore, the functional wall module can include a single or multiple movable platforms that may support or secure one or more objects. As such, movement of the movable platform(s) may position and/or selectively reposition such objects within the individual space.
US09593478B2 Non-bearing modular construction system
Methods and apparatus facilitate the construction of a building using prefabricated building units, each having a horizontal upper exterior surface and a plurality of vertical wall surfaces, wherein at least some of the prefabricated building units have at least one hollow column formwork structure. The prefabricated building units are lowered onto a pre-existing base at a construction site. A first story of the building is created by arranging a plurality of the prefabricated building units adjacent to each other on the base. Structural bearing material is applied to fill the hollow column formwork structures to create structural columns connected to the structural deck. Structural bearing material is applied to the horizontal upper exterior surfaces of the adjacent prefabricated building units to create a single structural deck over the prefabricated building units.
US09593475B2 Plumbing elbow
A pipe system has an elbow 70 with a snake-passing opening 72 (FIG. 3) that is normally closed by a plug 88, with the walls of the snake opening and plug constructed to avoid harmful wear during use of the snake. The elbow forms a nipple 82 that surrounds the snake opening. The nipple has threads (102, FIG. 4) on its outside so snake-caused wear does not initially occur in the threads. The snake opening has an axis 108, and the plug middle forms a cup 112 that extends axially inward to block a majority of the volume within the inner end of the nipple.
US09593471B2 Sanitary hydrant
A freeze resistant sanitary hydrant is provided that employs a reservoir for storage of fluid under the frost line or in an area not prone to freezing. To evacuate this reservoir, a means for altering pressure is provided that is able to function in hydrant systems that employ a vacuum breaker.
US09593470B2 Bucket corner, ground engaging tool and mutual mechanical attachment thereof
An earthmoving equipment bucket corner has a first portion, a second portion and an intermediate portion between the first and second portions, all in different planes to one another. A boss or lug is provided on the leading edge of the intermediate portion. The intermediate portion is angled relative to both the first and second portions, which alleviates the load stresses otherwise created in a traditional 90° corner. The first portion has a wall with a taper or bevel towards a forward edge. The second portion has a wall with a leading flared wall portion that widens the corner at the front. The intermediate portion is preferably at an included angle of around 120° to 170° with respect to the respective walls of the first and second portions.
US09593463B1 Mine management system and mine managing method
Provided is a mine management system for a mine where an unmanned vehicle operates in an operation area of the mine, including determining based on position data of a moving body which is different from the unmanned vehicle whether the moving body enters the operation area, starting monitoring abnormality including abnormality of at least one of communication state and position detection state of the moving body based on manipulation on an input device installed in the moving body, setting an entrance prohibited area where entrance of the unmanned vehicle is prohibited to include a position of the moving body and activating a function of expanding the entrance prohibited area when an abnormality is detected, and activating an alarm device installed in the moving body when it is determined that the moving body enters the operation area and the input device is not manipulated.
US09593462B2 Construction machine
A construction machine includes an engine unit, a body frame, and mounting portions. The engine unit includes an engine, a hydraulic pump driven by drive force of the engine, and a generator motor disposed between the engine and the hydraulic pump. The generator motor has a rotary shaft connected to an input shaft of the hydraulic pump and to an output shaft of the engine and a first housing fixed on an engine side and a second housing fixed on a hydraulic pump side. The engine is installed on the body frame. The mounting portions are provided to the engine and to the first housing to support the engine unit on the body frame.
US09593460B2 Fluid conveyance system for industrial machine
An industrial machine includes a frame supporting a boom, an elongated member movably coupled to the boom, an attachment, a conduit, and a reel supporting at least a portion of the conduit. The boom includes a first end coupled to the frame and a second end opposite the first end. The elongated member is movably coupled to the boom and includes a first end and a second end. The attachment is coupled to the second end of the elongated member. The conduit extends between the frame and the attachment. The reel is rotatably supported on a support shaft. The reel rotates about an axis of rotation to reel in and pay out the conduit as the elongated member moves relative to the boom.
US09593457B2 Method and system to manufacture native soil flowable fill
A method to manufacture native soil flowable fill includes hydro excavating native soil to form a hole at a first excavation, and transferring the native soil from the first excavation to a mixing tank. The method also includes adding a pozzolan component, cement and water to the mixing tank, mixing the native soil in the mixing tank with the added pozzolan component, cement and water to form the native soil flowable fill, and transferring the native soil flowable fill back to the first excavation and into the hole.
US09593456B2 Sheet piling and installation method
A sheet piling for mandrel-installed engagement with an identical adjacent sheet piling. The mandrel has a guide hook and a rotating toe protector. The sheet piling has a female interlocking feature with a pair of hooks and an engagement hook for releasably engaging the mandrel guide hook. The sheet piling also has a male interlocking feature with a pair of hooks configured to engage the pair of female hooks of an adjacent sheet piling in a multi-piling wall structure.
US09593455B2 Geotextile sheeting stabilized fiberglass swimming pool body
A preformed swimming pool assembly, including a preformed swimming pool body outer surface and a plurality of stabilizing sheets connected to the preformed swimming pool body outer surface. The stabilizing sheets may be extended away from the preformed swimming pool body for anchoring underground.
US09593451B2 Movable foil blade for papermaking on a fourdrinier, including the lead blade on the forming board box
A method for operably adjusting a forming board lead blade of a paper sheet forming machine of the type having a headbox for impinging a jet of slurry from a slice opening of the headbox onto the surface of a porous wire moving continuously in a horizontal machine direction over the forming board.
US09593449B2 Screening device
A screening device for fibrous stock suspensions of the paper industry includes at least two separate screening baskets which are connected axially behind one another in the interior of a reinforcing device in the form of a back-up cylinder. A variable-diameter intermediate ring is arranged between the screening baskets. The reinforcing device has a cover part and a bottom part. By way of axial tensile force loading of the arrangement, the intermediate ring is loaded so as to bear radially in the circumferential direction in a gap-free manner against the associated axial ends or screening basket flanges of the screening baskets. The screening baskets are then clamped and fixed in a centrally positioned manner by the intermediate ring in cooperation with the end-side flange of the reinforcing device, the cover part, the bottom part and the intermediate ring.
US09593446B2 Method of producing wire rope
With a wire rope comprising at least one plastic core (11) and a number of wire strands (15) twisted around the latter a helical groove (20) is respectively produced by machining around the periphery of the plastic core (11) for each wire strand (15). The cross section of these helical grooves (20) is respectively matched to the outside diameter of the wire strands (15). The plastic core (11) is provided with the helical grooves (20) for receiving the wire strands (15) by this machining directly before the wire strands (15) are wound onto said core. By thus forming the wire rope by means of this machining in order to produce helical grooves of the plastic core, optimal guiding of the wire strands in the twisted state is achieved, and so overall there are improvements to the properties of the wire rope.
US09593444B2 Method for producing sizing agent-coated carbon fibers, and sizing agent-coated carbon fibers
Disclosed is a method for producing a sizing agent-coated carbon fibers, wherein at least one kind of sizing agent that is selected from the group consisting of sizing agents (a), (b) and (c) is used for coating, in each of the sizing agents a bi- or higher functional epoxy compound (A1) and/or an epoxy compound (A2) being used as a component (A), and the epoxy compound (A2) having a mono- or higher functional epoxy group and at least one functional group that is selected from among a hydroxyl group, an amide group, an imide group, a urethane group, a urea group, a sulfonyl group and a sulfo group. The sizing agent is applied to carbon fibers and the resulting is subjected to a heat treatment within the temperature range of 160-260° C. for 30-600 seconds.
US09593442B2 Method to control a drying cycle of a laundry treating appliance
An apparatus and method for controlling a drying cycle of a laundry treating appliance by monitoring a temperature of the exhaust air flow.
US09593441B2 Lint catching system and exhaust assembly
A lint catching system is provided for a clothes dryer. The lint catching system filters lint from exhaust air expelled from the clothes dryer.
US09593440B2 Method and apparatus for controlling the liquid filling in a laundry treating appliance
Disclosed is a method of operating a horizontal axis laundry treating appliance to correct for an error in sensing an amount of supplied liquid caused by a determined change in the attitude of an associated wash tub.
US09593437B2 Level cut loop looper and clip assembly
A level cut loop looper or hook and clip assembly for a tufting machine includes at least one module carrying a series of level cut loop loopers or hooks. Each level cut loop looper or hook generally can include a looper body along which a clip is slidably moved. Each clip will be moved between retracted and extended positions as the level cut loop loopers or hooks are reciprocated toward and away from engagement with their associated needles of the tufting machine. Actuators can be engaged to secure the clips in their extended positions as needed to selectively form cut and loop pile tufts in a backing material.
US09593435B2 Grafted para-aramid fiber and method of making
A fiber comprising poly(p-phenylene terephthalamide) having monomers such as N-(4-vinylphenyl)maleimide grafted onto the fiber surface.
US09593434B2 Alkyl push flow for vertical flow rotating disk reactors
In a rotating disk reactor (1) for growing epitaxial layers on substrate (3), gas directed toward the substrates at different radial distances from the axis of rotation of the disk has substantially the same velocity. The gas directed toward portions of the disk remote from the axis (10a) may include a higher concentration of a reactant gas (4) than the gas directed toward portions of the disk close to the axis (10d), so that portions of the substrate surfaces at different distances from the axis (14) receive substantially the same amount of reactant gas (4) per unit area. A desirable flow pattern is achieved within the reactor while permitting uniform deposition and growth of epitaxial layers on the substrate.
US09593431B2 Electroplating systems
Electroplating systems that include a plurality of electrodes, a power supply operably coupled to the plurality of electrodes, a platen for bearing a substrate on which metal features are to be formed, and an electrode support are disclosed. The electrode support may be configured for suspending the electrode assembly over an upper surface of the substrate disposed on the platen in spaced relation to and in alignment with the substrate or for supporting the electrode assembly in a stationary position over the substrate when the voltage is applied across the plurality of electrodes. The electrodes may be adjacent, mutually spaced and electrically isolated and connected in series so as to be oppositely polarized when the voltage is applied thereacross or may be connected so as to have alternating polarities when the voltage is applied thereacross.
US09593430B2 Electrochemical deposition method
The present invention is to provide a substrate holder which can effect a more complete sealing with a sealing member and makes it possible to take a substrate out of the substrate holder easily and securely, and also a plating apparatus provided with the substrate holder. The substrate holder includes: a fixed holding member and a movable holding member for holding a substrate therebetween; a sealing member mounted to the fixed holding member or the movable holding member; and a suction pad for attracting a back surface of the substrate held between the fixed holding member and the movable holding member.
US09593429B2 Methods of fabricating photonic crystal
Provided are a method of fabricating a photonic crystal having a desired photonic bandgap, and a method of fabricating a color filter, including providing a photonic crystal solution in which a plurality of colloidal particles that are electrically charged are dispersed, mixing a photopolymerizable monomer mixture in the photonic crystal solution to form a photopolymerizable monomer-crystal mixture, applying an electric field to the photopolymerizable monomer-crystal mixture to electrically control intervals between the plurality of colloidal particles, and irradiating ultraviolet light to the photopolymerizable monomer-crystal mixture to photopolymerize the monomer mixture to form the photonic crystal or the color filter.
US09593427B2 Method for forming pattern and catalyst and electronic element using method therefor
Provided are a method for forming a pattern, and a catalyst and an electronic element using the method. The method for forming a pattern comprises the steps of: preparing, on a surface, a substrate sequentially including a photoconductive material layer and an oxide layer; making an area, on which a pattern is to be formed, on the oxide layer of the substrate, come into contact with an electrolyte; connecting the substrate and the electrolyte to a first electrode and a second electrode connected to a power source, respectively; and selectively irradiating light from a light source to the electrolyte and applying a voltage to the first electrode or the second electrode, thereby directly forming the pattern on the oxide layer of the substrate.
US09593426B2 Through silicon via filling using an electrolyte with a dual state inhibitor
A method for electrofilling large, high aspect ratio recessed features with copper without depositing substantial amounts of copper in the field region is provided. The method allows completely filling recessed features having aspect ratios of at least about 5:1 such as at least about 10:1, and widths of at least about 1 μm in a substantially void-free manner without depositing more than 5% of copper in the field region (relative to the thickness deposited in the recessed feature). The method involves contacting the substrate having one or more large, high aspect ratio recessed features (such as a TSVs) with an electrolyte comprising copper ions and an organic dual state inhibitor (DSI) configured for inhibiting copper deposition in the field region, and electrodepositing copper under potential-controlled conditions, where the potential is controlled not exceed the critical potential of the DSI.
US09593425B2 Confinement of reaction components at electrode surface
A CO2 reduction electrode includes an active layer on an electrode base. The active layer includes a polymer that includes one or more reaction components selected from a group consisting of a CO2 reduction catalyst and an activator that bonds CO2 so as to form a CO2 reduction intermediate.
US09593420B2 System for manufacturing graphene on a substrate
A method and apparatus for manufacturing a lattice structure of a material on a substrate, wherein the process may be performed at atmospheric pressure, may not require a metallic substrate, may be capable of continuously generating the lattice structure as long as desired, may be as thin as a single layer of the lattice material, and may create the lattice structure with any material that is capable of being vaporized to create a stream of ionized particles and then condensed to form the lattice structure.
US09593417B2 Gas line weldment design and process for CVD aluminum
A system of gas lines for a processing chamber and a method of forming a gas line system for a processing chamber are provided. The system of gas lines includes electropolished multi-way valves that connect electropolished linear gas lines. By using multi-way valves rather than tee-fittings and electropolishing the linear gas lines, the nucleation of contaminating particles in the system of gas lines may be reduced.
US09593413B2 Composite materials for battery applications
A process for producing nanocomposite materials for use in batteries includes electroactive materials are incorporated within a nanosheet host material. The process may include treatment at high temperatures and doping to obtain desirable properties.
US09593409B2 Dielectric film forming apparatus and method for forming dielectric film
A dielectric film forming apparatus and a method for forming a dielectric film so as to form a dielectric film with a (100)/(001) orientation. A dielectric film forming apparatus includes a deposition preventive plate heating portion that heats a deposition preventive plate disposed in a position where particles discharged from a target adhere. Sputtering gas is introduced from a sputtering gas introduction unit into a vacuum chamber. The deposition preventive plate is heated to a temperature higher than a film forming temperature so as to emit vapor from a thin film adhered to the deposition preventive plate. After a seed layer is formed on a substrate, the substrate is heated to the film forming temperature, and AC voltage is applied to the target from a power supply and then, the target is sputtered so as to form a dielectric film on the substrate.
US09593407B2 Direct liquid deposition
Liquid precursor material of a coating substance and a solvent is provided in a reservoir (STEP1, STEP1′). In one variant the liquid precursor material is distilled (STEP2), the resultant liquid coating substance is vaporized (STEP3) and ejected through a vapor distribution nozzle arrangement (7) into a vacuum recipient (3) and onto substrate 5 to be coated. Alternatively, the liquid precursor material is directly vaporized (STEP3′). From the two-component vapor coating substance vapor is applied to substrate 5′ to be coated. In this variant separation of solvent vapor and coating substance vapor is performed especially downstream vaporizing (STEP2′).
US09593406B2 Optical device and manufacture thereof
The invention provides an optical device and manufacture thereof. The optical device of the invention includes a transparent substrate, a seeding layer, a plurality of nano-rods and a protection layer. The seeding layer is formed to overlay an entrance surface and an exit surface of the transparent substrate. The plurality of nano-rods are formed on the seeding layer. The protection layer is formed to completely overlay the plurality of nano-rods.
US09593403B2 Method for ejecting molten metals
In a method for ejecting droplets of a molten metal, the metal is an alloy including a first metal and a second metal. During a jetting operation, the second metal segregates from the first metal. A method of using such alloy is also disclosed herein.
US09593402B1 System including a pump for treating wire in molten fluids
A system for treating wire includes an elongated vessel that contains a molten fluid. A pump is disposed in the molten fluid in the vessel. The pump includes an elongated discharge conduit extending for at least a portion of the length of the vessel. Conveyance structure enables the wire to be conveyed through the molten fluid. Operation of the pump enables a temperature of the molten fluid in the vessel to be changed. The wire is heat treated as a result of passing through the molten fluid.
US09593401B2 Continuous annealing furnace for steel strip, continuous annealing method, continuous galvanizing apparatus and method for manufacturing galvanized steel strip (as amended)
Provided is a vertical annealing furnace, in which a heating zone and a soaking zone are communicated with each other in the upper part of the furnace, in which a part of the furnace other than the communicated parts is separated by a dividing wall, in which part of the furnace gas is suctioned into a refiner having a deoxidation device and a dehumidification device which is placed outside the furnace to decrease the dew point of the gas by removing oxygen and moisture from the gas and such that the resultant gas having a decreased dew point is returned into the furnace, in which a gas suction port into the refiner is located in the lower part of the connection part between the soaking zone and the cooling zone and in which one or more gas suction ports are located in the parts of the heating zone and/or the soaking zone outside of an area within 6 m in the vertical direction and 3 m in the longitudinal direction of the furnace from the steel strip entrance in the lower part of the heating zone.
US09593397B2 Magnesium alloy with adjustable degradation rate
An alloy and an implant having a three-dimensional structure based on such alloy. The alloy comprises a MgZnCa alloy containing nanosized precipitates being less noble than the Mg matrix alloy and having a Zn content ranging 0.1 wt. % Zn to 2 wt. % Zn and a calcium content ranging from 0.2 wt. % to 0.5 wt. %, and having less than 0.04 wt. % of one or more other elements with the remainder being Mg. For these micro-alloys, any second phase generated during the solidification process can be completely dissolved by a solution heat treatment. Finely dispersed nanosized precipitates can then be generated by a subsequent aging heat treatment step. These precipitates are used to “pin” the grain boundaries and to prevent the coarsening of the grain structure during further processing to achieve grain sizes below 5 μm.
US09593391B2 Strip, sheet or blank suitable for hot forming and process for the production thereof
Disclosed is a strip, sheet or blank suitable for hot forming at a temperature of 700° C. or above, including a substrate of hot formable steel, optionally coated with an active corrosion protective coating. The optionally coated steel substrate is provided with a ceramic based coating having a thickness of at most 25 micron. Also disclosed is a process to produce such strip, sheet or blank.
US09593390B2 Heat treatment method
The heat treatment method of the present invention includes: a first step of mist cooling a treatment object retained at a prescribed temperature by supplying mist-like coolant, to a target temperature near to and higher than a first transformation point at which a structure of the treatment object begins to be transformed into a prescribed structure; a second step, following the first step, of retaining the treatment object for a prescribed time in a state where supply of mist-like coolant is stopped; and a third step, following the second step, of cooling the treatment object to a temperature lower than or equal to the first transformation point. According to the present invention, it is possible to provide a heat treatment method capable of suppressing irregularity and deformation in the structure of the treatment object.
US09593389B2 Steel wire rod for bearing steel, manufacturing method of steel wire rod for bearing steel, heat treatment method of steel bearing, steel bearing and soaking method of bearing steel
A heat treatment method of manufacturing high carbon bearing steel having excellent abrasion resistance and fatigue resistance, a steel wire rod for high carbon bearing steel subjected to the heat treatment, a manufacturing method of the steel wire rod, high carbon bearing steel manufactured by the heat treatment and a soaking method of a steel bloom used for manufacturing the steel wire rod. The heat treatment method of bearings includes the steps of: quenching a bearing-shaped steel part containing, by weight, 0.5% to 1.20% carbon and 1.0% to 2.0% silicon; and partitioning the quenched steel part at a temperature ranging from Ms−100° C. to Ms for at least 10 minutes, where Ms represents a temperature at which formation of martensite will start.
US09593386B2 Virus causing respiratory tract illness in susceptible mammals
The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single-stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.
US09593385B2 Selective detection of Haemophilus influenzae
A process for detecting Haemophilus influenzae nucleic acid in a sample includes producing an amplification product by amplifying a Haemophilus influenzae nucleotide sequence and measuring the amplification product to detect Haemophilus influenzae in the sample. Some embodiments allow direct serotype determination in a single step assay. Also provided are reagents and methods for detecting and distinguishing Haemophilus influenzae from other infectious agents. A kit is provided for detecting and quantifying Haemophilus influenzae in a sample.
US09593375B2 Nucleic acid analysis using emulsion PCR
The present invention provides methods for analyzing large nucleic acids including chromosomes and chromosomal fragments. In one aspect, the present invention provides a method of nucleic acid analysis comprising the steps of (a) obtaining a sample of nucleic acid comprising at least one chromosome or fragment greater than about 1000 base pairs in length and containing a target region; (b) creating an emulsion in which each drop of the emulsion contains an average of between about 0-2, 0-1.75, 0-1.5, 0-1.0, 0-0.75, 0-0.5, or fewer chromosomes or fragments of step (a), (c) performing emulsion PCR, (d) quantifying the number of emulsion droplets containing amplified nucleic acid from the target region; (e) calculating the ratio of droplets containing amplified nucleic acid from the target region to total droplets; and (f) comparing the ratio of step (e) to a reference ratio representing a known genotype.
US09593372B2 Nanopore based sequencer
The present invention is directed to systems, devices and methods for identifying biopolymers, such as strands of DNA, as they pass through a constriction such as a carbon nanotube nanopore. More particularly, the invention is directed to such systems, devices and methods in which a newly translocated portion of the biopolymer forms a temporary electrical circuit between the nanotube nanopore and a second electrode, which may also be a nanotube. Further, the invention is directed to such systems, devices and methods in which the constriction is provided with a functionalized unit which, together with a newly translocated portion of the biopolymer, forms a temporary electrical circuit that can be used to characterize that portion of the biopolymer.
US09593369B2 Direct nucleic acid analysis
The present disclosure provides methods, systems, and apparatuses for collecting and/or amplifying nucleic acids. In general, provided methods, systems, and apparatuses involve contacting a sample including a nucleic acid with a nucleic acid amplification reagent without purification of nucleic acids from the sample.
US09593368B2 Methods for amplifying nucleic acids on substrates
A method is provided herein, the method includes: applying a sample comprising target nucleic acids to a sample application zone of a substrate; applying an aqueous buffer to the sample application zone of the substrate to washes away one or more inhibitors present on the sample application zone; and applying an isothermal nucleic acid amplification reaction mixture to the sample application zone to amplify the target nucleic acid to form a nucleic acid amplification product. The target nucleic acid having a first molecular weight is substantially immobilized at the sample application zone and wherein the amplification product having a second molecular weight.
US09593364B2 Detecting a target molecule in a sample using a dual-antibody quantitative fluorescence-based detection method
A kit and method for detection of a target in a sample. An assay mixture provided in the kit and used in the method includes a first probe with a first antibody recognizing a first epitope of the target and conjugated to an RNA oligonucleotide; a second probe with a second antibody recognizing a second epitope of the target and conjugated to a DNA oligonucleotide; a reverse primer with a first region complimentary to the RNA oligonucleotide and a second region complimentary to the DNA oligonucleotide; and a reverse transcriptase that creates a DNA transcription product from the RNA oligonucleotide using the reverse primer only if the RNA oligonucleotide and the DNA oligonucleotide are in close proximity. If the target is present in the sample, the reverse primer binds the RNA oligonucleotide and the DNA oligonucleotide to bring the RNA oligonucleotide and the DNA oligonucleotide in close proximity.
US09593363B2 Methods and models for assessing anti-aging benefits of agents
A screening method for identifying an agent as effective for providing an anti-aging skin benefit is provided. The screening method includes culturing first and second human skin samples from about 3 days to about 19 days, wherein the first and second human skin samples are derived from a human skin surgical waste tissue. The first human skin sample is contacted with at least one test agent. The second human skin sample is contacted with a positive control. Transcriptional profiles are generated from the first and second human skin samples, and the at least one test agent is identified as effective for providing an anti-aging skin benefit when the transcriptional profiles of at least two genes show a similar directional change in comparison to one or more untreated control tissue samples.
US09593360B2 Measurement of brain CDP-diacylglycerol synthase 1 enzyme and uses thereof
Provided herein are methods of diagnosing depressive disorders in a subject by comparing a CDP-diacylglycerol synthase 1 enzyme activity or expression level to enzyme activity or expression level of CDP-diacylglycerol synthase 1 in a control subject. Also herein are methods of predicting therapeutic efficacy of an antidepressant drug in a subject with depressive disorders by monitoring enzyme activity or expression level of CDP-diacylglycerol synthase 1 in the subject. Further provided herein are methods of identifying a compound effective to treat or alleviate the symptoms of depression by monitoring enzyme activity or expression level of CDP-diacylglycerol synthase 1 in a tissue. Further provided are kits for diagnosing depressive disorders.
US09593359B2 Liquid to liquid biological particle concentrator with disposable fluid path
Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrate biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. All conduits by which the disposable tip attaches to the instrument are combined into a single connection point on the upper end of the tip.
US09593358B2 Method and medium for detecting Shiga toxin-producing Escherichia coli bacteria
The present invention relates to a method for specific and direct detection of Shiga toxin-producing Escherichia coli bacteria in a sample using a selective and differential isolation medium for Shiga toxin-producing Escherichia coli bacteria comprising at least one chromogenic agent and tellurite.
US09593355B2 Process for the production of optimised liquefied lignocellulosic substrate
The present invention concerns a production of liquefied lignocellulosic substrate by enzymatic reaction. 10% to 40% by weight dry matter of pre-treated lignocellulosic substrate is contacted, with water and enzymes at 0.1 to 60 mg of enzymes per gram of cellulose for a period of 1 to 24 hours. Over time, at least the value of one of the rheological characteristics of the reaction medium is measured. If a reduction of the value is detected over time, the following step a) is carried out: a) the feeding flow rate of pre-treated lignocellulosic substrate is increased, with or without modification of the flow rate of enzymes and/or water; If an increase of the value is detected over time, a step b) is carried out: b) the feeding flow rate of water and/or enzymes is increased, with or without modification of the flow rate of pre-treated lignocellulosic substrate.
US09593353B2 Microorganisms for production of O-succinylhomoserine and method for production of O-succinylhomoserine using the same
The present invention relates to a polypeptide having a resistant to feedback inhibition by methionine and an activity of homoserine O-succinyltransferase, a O-succinyl homoserine-producing microorganism expressing the polypeptide, and a method for producing O-succinyl homoserine using the same.
US09593350B2 Lactate dehydrogenase mutant, polynucleotide coding for the mutant, yeast cell including the polynucleotide, method of preparing the mutant, and method of producing the lactate using the same
A lactate dehydrogenase mutant, a polynucleotide encoding the mutant, a recombinant yeast cell including the polynucleotide, and a method of preparing the mutant and a method of producing lactate by using the same.
US09593349B2 Fermentative production of alcohols
The invention relates to the development of microorganisms capable of producing fermentation products via an engineered pathway in the microorganisms. The invention also relates to microorganisms with improved cell viability and methods to improve cell viability and cell productivity of a microorganism.
US09593348B2 System and method for continuous enzyme addition to a fermentation process
A method for controlling a fermentation process includes injecting a mash into a fermenter and injecting an enzymatic additive into the fermenter on a continuous basis. The enzymatic additive is injected on a continuous basis during at least two time periods: during a batch fill and after the batch fill. The method may be used to control the fermentation processes of one or more fermenters operating in parallel.
US09593347B2 Identification of mutations in herpes simplex virus envelope glycoproteins that enable or enhance vector retargeting to novel non-HSV receptors
The invention provides modified HSV vectors that exhibit enhanced entry of cells, either through direct infection and/or lateral spread. In one aspect, HSV vectors of the present invention can directly infect cells through interaction with cell proteins other than typical mediators of HSV infection. In another aspect, the invention provides an HSV vector, which exhibits lateral spread in cells typically resistant to HSV lateral spread, such as cells lacking gD receptors. The invention further provides DNA encoding mutant forms of the HSV gB and gH glycoproteins, stocks of the inventive virus, and methods for effecting viral targeting and efficient entry of cells. The invention also pertains to the use of the inventive vectors for treating cancers.
US09593345B2 Bacillus thuringiensis gene with coleopteran activity
The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests including, but not limited to, insect pests belonging to the orders Coleoptera and Lepidoptera. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, polynucleotide constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.
US09593342B2 Methods for producing polypeptides in enzyme-deficient mutants of Fusarium venentatum
The present invention relates to methods of producing a polypeptide, comprising: (a) cultivating a mutant of a parent Fusarium venenatum strain in a medium for the production of the polypeptide, wherein the mutant strain comprises a polynucleotide encoding the polypeptide and one or more (several) genes selected from the group consisting of pyrG, amyA, and alpA, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of orotidine-5′-monophosphate decarboxylase, alpha-amylase, and alkaline protease, respectively, compared to the parent Fusarium venenatum strain when cultivated under identical conditions; and (b) recovering the polypeptide from the cultivation medium. The present invention also relates to enzyme-deficient mutants of Fusarium venenatum strains and methods for producing such mutants.
US09593339B1 Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment
The present invention uses co-expression of protease inhibitors and protease sensitive therapeutic agents including phage and phagemids delivering peptides, therapeutic antibodies, DNA and RNA-based therapeutics that results in treating inflammation of a variety of disorders including psoriasis, atopic dermatitis and inflammatory bowel disease. The invention also provides bacteria that inhibit the growth of intestinal parasites such as worms, and deliver siRNA or miRNA that have specific anti-parasitic effects that results in the reduction or elimination of the parasite.
US09593338B2 Synthetic transcriptional control elements and methods of generating and using such elements
Provided herein are nucleic acid constructs that contain a synthetic control element that includes a cis-regulator of translation, and an adapter translation-coupled regulator of transcription. Further provided herein are nucleic acid constructs that contain nucleic acid sequences under the control of the synthetic control elements. Also provided are compositions and methods related to the nucleic acid constructs.
US09593337B2 Method for identifying biologically active oligonucleotides capable of modulating the immune system
The present invention relates to methods of identifying oligonucleotides capable of modulating the immune system in a mammalian subject, comprising analysis of which tertiary structural type said oligonucleotide adopts, in phosphate-buffered saline solution. Further, the invention provides oligonucleotides identifiable by the methods of the invention and to their use in methods of treating diseases, such as inflammatory diseases, autoimmune diseases, infectious diseases, neurodegenerative diseases and cancer.
US09593336B2 Compositions and methods for treating cancer and other diseases
Aptamers and improved aptamers are provided with enhanced efficacy for binding to target molecules in vivo or for treating cancer or other diseases. Such improvements in aptamers are provided that enhance in vivo efficacy such as binding to the target molecule or enhancing anti-cancer activity. Such improvements also include stability to serum nucleases, reduced binding to a soluble form of the target molecule, increased avidity, affinity or specificity to the target molecule on a cell surface, increased lifetime in circulation, or any combination of the foregoing. Improvements are provided by truncation, multimerization, including at least one non-natural nucleic acid, adding a 3′ or 5′ polyethylene glycol, or any combination thereof. Aptamers for treatment of autoimmune diseases are also provided.
US09593332B2 Methods and compositions for targeting immunoglobulins
The present invention relates to compositions and methods for targeting immunoglobulins and immunoglobulin-producing plasma cells. In particular, the present invention provides nucleic acid based compounds for targeting immunoglobulins for research, screening, and therapeutic applications.
US09593331B2 Double-stranded nucleic acid molecule for gene expression control
Provided are an improved double-stranded nucleic acid molecule involved in gene expression control mediated by a gene silencing mechanism, a method of producing the molecule, and a pharmaceutical composition comprising the double-stranded nucleic acid molecule. The double-stranded nucleic acid molecule for gene expression control comprises an antisense strand having a length of 18 to 28 nucleotides and a sense strand including a complementary moiety composed of a sequence sufficiently complementary to the antisense strand and a protruding single-stranded 5′-end moiety having a length of 2 to 100 nucleotides. The sense strand and the antisense strand form base pairs via the complementary moiety. The method produces such a double-stranded nucleic acid molecule, and the pharmaceutical composition contains such a double-stranded nucleic acid molecule as an active ingredient.
US09593328B2 Method of nucleic acid amplification
A nucleic acid molecule can be annealed to an appropriate immobilized primer. The primer can then be extended and the molecule and the primer can be separated from one another. The extended primer can then be annealed to another immobilized primer and the other primer can be extended. Both extended primers can then be separated from one another and can be used to provide further extended primers. The process can be repeated to provide amplified, immobilized nucleic acid molecules. These can be used for many different purposes, including sequencing, screening, diagnosis, in situ nucleic acid synthesis, monitoring gene expression, nucleic acid fingerprinting, etc.
US09593327B2 Identification of antigen or ligand-specific binding proteins
The present invention discloses novel methods for the generation, expression and screening of diverse collections of binding proteins such as antibodies or fragments thereof in vertebrate host cells in vitro, for the identification and isolation of ligand- or antigen-specific binding proteins. The methods disclosed herein allow the expression of diverse collections of binding proteins from at least one vector construct, which optionally can give rise to collections of diverse binding proteins upon transfer and expression into vertebrate host cells in situ.
US09593314B2 Binding molecules with antitumoral activity
The present invention relates to a binding molecule that specifically binds to two different epitopes of an antigen expressed on tumor cells, wherein the binding molecule comprises: (a) a first binding (poly)peptide that specifically binds to a first epitope of said antigen expressed on tumor cells, wherein said first binding (poly)peptide is a Fyn SH3-derived polypeptide; and (b) a second binding (poly)peptide that specifically binds to a second epitope of said antigen expressed on tumor cells. The present invention further relates to a nucleic acid molecule encoding the binding molecule of the invention, a vector comprising said nucleic acid molecule as well as a host cell or a non-human host transformed with said vector. The invention further relates to a method of producing a binding molecule of the invention as well as to pharmaceutical and diagnostic composition. Moreover, the present invention also relates to the binding molecule, the nucleic acid molecule, the vector or the host cell of the invention for use in the treatment of tumors.
US09593309B2 Media for culturing, preserving, and administering regenerative cells
A culture media, media supplement, or soluble matrix for cryopreservation or enhanced regenerative cell growth in culture and maintenance of multi-lineage differentiation potentiation. The inventive culture media, media supplement, or soluble matrix comprises a GAG composition comprising a sulfated GAG, such as chondroitin sulfate. A soluble matrix, a cell administration package or kit comprising the soluble matrix and a device for cell administration, and a method of use thereof, for administration of regenerative cells for treating a joint disease or other weakened or damaged tissue comprising the specified GAG compositions are further provided.
US09593306B2 Differentiation of pluripotent stem cells
The present invention is directed to methods to differentiate pluripotent stem cells. In particular, the present invention is directed to methods and compositions to differentiate pluripotent stem cells into cells expressing markers characteristic of the definitive endoderm lineage comprising culturing the pluripotent stem cells in medium comprising a sufficient amount of GDF-8 to cause the differentiation of the pluripotent stem cells into cells expressing markers characteristic of the definitive endoderm lineage.
US09593304B2 Three-dimensional discontinuous entity for cell culturing
The present invention is related to methods and materials for culturing and transporting stem cells in a three-dimensional culture. The materials comprise cellulose nanofibrils in a form of three-dimensional discontinuous entities in a biocompatible hydrogel.
US09593302B1 Method and system for harvesting micro organisms
In an embodiment of the invention, aqueous growth medium in a pond can be used to grow algae which can be pumped to a primary dewatering device where the algae can be separated from the harvested growth media based on the flow of the harvested growth media and gravity. The flow through the primary de-watering device can be optimized to maintain log phase growth in the pond, while minimizing the pumping cost and maximizing the concentration of total solids in the primary de-watered algae.
US09593298B2 Composition comprising fatty acyl isethionate and synthetic wax and method producing the same
A method of preparing a component of a personal care bar, the method comprising: (a) providing a composition comprising an isethionate surfactant at a temperature of at least 20° C.; (b) combining the composition comprising the isethionate surfactant with a synthetic 5 wax and optional further components at a temperature of at least 120° C.; and (c) cooling the mixture obtained in step (b).
US09593297B2 Compositions for removing residues and related methods
Compositions for removing residues from a semiconductor structure. The compositions comprise water, a base, a polydentate chelator, a degasser, and a fluorine source. The compositions comprise greater than or equal to approximately 99 wt % of the water and are formulated to exhibit a pH of from approximately 10.0 to approximately 12.0. Methods of forming and using the compositions are also disclosed.
US09593295B2 Surfactants with lower CMC, and surfactant systems and detergents containing said surfactants
The invention relates to surfactants of the formula (I), in which R1 stands for —H or —CH3; R2, R3, R4, R5, R6 independently stand for —H, —CH3, —CH2CH3, —CH2CH2CH3, —CH(CH3)2, —CH2CH2CH2CH3, —CH2CH(CH3)2, —CH(CH3)CH2CH3, —C(CH3)3, —OH, —OCH3, —OCH2CH3, —OCH2CH2CH3, —OCH(CH3)2, a linear or branched alkyl group containing 8 to 20 C atoms, or —SO3−X+; X+ stands for a monovalent cation or the nth part of an n-valent cation; exactly one radical R2, R3, R4, R5, R6 stands for —SO3−X+; and exactly one radical R2, R3, R4, R5, R6 stands for a linear or branched alkyl radical containing 8 to 20 C atoms.
US09593292B2 Engine lubricants containing a polyether
A lubricant comprising (a) an oil of lubricating viscosity; (b) a polyether of number average molecular weight 1000 to 10,000; said polyether comprising alkylene oxide monomer units, where the alkylene group contains 3 to 6 carbon atoms, and ethylene oxide monomer units; and (c) one or more anti-foam agents, where the lubricant has a sulfated ash content of less than about 0.7 percent, is useful for lubricating a stationary gas engine where the engine drives a compressor and where both the engine and the compressor are lubricated with the same lubricant.
US09593289B2 Corrosion inhibiting hydraulic fluid additive
Corrosion inhibiting hydraulic fluid additives, kits, and methods are disclosed. The hydraulic fluid additive may be adapted for use with brake fluid in vehicular brake systems. The kits may include an additive, a hydraulic fluid tester, and/or correlated information on test results and hydraulic fluid service actions.
US09593283B2 Method of and apparatus for controlling a gasifier
A method of controlling a circulating fluidized bed gasifier includes feeding first and second portions of particulate material to be gasified through inlets in a gasifier. Oxygen and steam are fed through a bottom grid into a lower portion of the gasifier to fluidize the bed. Product gas and entrained particles are discharged from an upper portion of the gasifier. Particles are separated from the product gas and a portion of the separated particles is returned to the lower portion. A portion of the returned particles is oxidized to generate heat. Heat and oxidizing products from the lower portion are transferred to the center portion to generate the product gas. A ratio of the first and second portions of particulate material to be gasified is determined on the basis of a measured temperature profile so as to control the vertical temperature distribution in the gasifier.
US09593282B2 Removal of hydrogen sulfide as ammonium sulfate from hydropyrolysis product vapors
A system and method for processing biomass into hydrocarbon fuels that includes processing a biomass in a hydropyrolysis reactor resulting in hydrocarbon fuels and a process vapor stream and cooling the process vapor stream to a condensation temperature resulting in an aqueous stream. The aqueous stream is sent to a catalytic reactor where it is oxidized to obtain a product stream containing ammonia and ammonium sulfate. A resulting cooled product vapor stream includes non-condensable process vapors comprising H2, CH4, CO, CO2, ammonia and hydrogen sulfide.
US09593276B2 Reversibly coagulatable and redispersable polymer including at least one monomer including a switchable-amphiphilic functional group and methods of using the same
The present invention relates to a polymer including at least one monomer comprising a switchable-amphiphilic functional group. Various embodiments provide a methods of treating a subterranean formation with the polymer, compositions including the polymer, and methods of making compositions including the polymer.
US09593273B2 Refrigerant mixtures
Use of a gaseous mixture, selected from the group consisting of—propylene in a concentration from 90% to 99% by weight and a gas selected from the group consisting of butene, ethylene and ethane or mixtures thereof in a concentration from 1% to 10% by weight; as replacement or alternative refrigerant gas for R404A, R507A and/or R407C, and/or other replacement or alternative refrigerants for R404A, R507A and R407C containing HFC (hydrofluorocarbons), HFO (hydrofluoro olefins) and HFE (hydrofluoro ethers).
US09593272B2 Silica for CMP, aqueous dispersion, and process for producing silica for CMP
To reduce scratches during polishing while ensuring an appropriately high polishing rate, provided are a silica for CMP satisfying the following (A) to (C), an aqueous dispersion using a silica for CMP, and a method of producing a silica for CMP: (A) a BET specific surface area of 40 m2/g or more and 180 m2/g or less; (B) a particle density measured by a He-gas pycnometer method of 2.24 g/cm3 or more; and (C) a coefficient of variation in primary particle diameter calculated by TEM/image analysis of 0.40 or less.
US09593266B2 Method of manufacturing a self-sealing composition
A self-sealing elastomer composition that includes a diene elastomer, a hydrocarbon resin with a given softening temperature, and a liquid plasticizing agent, is manufactured according to a process that includes successive stages. In one stage, the hydrocarbon resin is incorporated in the diene elastomer by kneading the resin and the elastomer in a mixer at or up to a temperature referred to as “hot compounding” temperature, which is greater than the softening temperature of the resin, in order to obtain a masterbatch. In another stage, the liquid plasticizing agent is incorporated in the masterbatch by kneading the agent and the masterbatch in the same mixer or in another mixer, in order to obtain the self-sealing composition. The self-sealing composition then is formed dimensionally.
US09593265B2 Adhesive composition
The invention provides for an adhesive composition that can both be used as melt adhesive composition and as drying adhesive composition. Such an adhesive composition comprises a thermoreversible gelling starch, a bonding starch and a plasticizer.
US09593264B2 Electrically conductive heat-activated adhesive compound
An adhesive film, which can be bonded when heat-activated, comprising a) a polymer-metal blend comprising at least one adhesive which can be bonded when heat-activated, and at least one metal component melting in the temperature range from 50° C. to 400° C., and b) at least one fibrous, electrically conductive filler, the filler being present at least partly in the form of a bound fiber network with the metal component.
US09593262B2 Shrink films and related combinations and methods
The present subject matter provides a shrink film free of silicon-containing material, fluorine-containing material, and solvent-formed seams. The shrink film utilizes a water soluble layer covering an adhesive layer. The water soluble layer is in dry form and non-tacky, allowing processing of the shrink film subsequent to adhesive application to the shrink film. When the water soluble layer is dissolved, the adhesive layer is exposed and is capable of forming a permanent bond. The adhesive can be used to form a seam in the film and/or can be used to form a bond between the film and a substrate. The water soluble layer facilitates removal of an optional release liner from the adhesive. A substrate with the shrink film attached thereto and a related method of attaching a heat shrinkable film to a substrate are also disclosed.
US09593261B2 Polishing agent, polishing method, and liquid additive for polishing
The present invention relates to a polishing agent including: cerium oxide particles; a water-soluble organic polymer having at least one selected from a carboxylic acid group and a salt of carboxylic acid; a water-soluble polyamide having at least one selected from a tertiary amino group and an oxyalkylene chain in a molecule thereof; and water, in which the polishing agent has a pH of 7 or less.
US09593259B2 Polishing composition
A polishing composition of the present invention contains: a polyvinyl alcohol resin having a 1,2-diol structure in its side chain, the polyvinyl alcohol resin being a copolymer of a monomer represented by Formula (1) below and a vinyl ester monomer; an organic acid; and abrasive grains whose surfaces are chemically modified so as to have a minus zeta potential on the surfaces in a solution with a pH of 2.0 or more and to have no isoelectric point: (where R1 to R6 each independently denote a hydrogen atom or an organic group, X denotes a single bond or a linking group, and R7 and R8 each independently denote a hydrogen atom or R9—CO— (where R9 denotes an alkyl group)).
US09593256B2 Low-solvent polyacrylate copolymer dispersions
The present invention relates to an aqueous secondary copolymer dispersion comprising a copolymer (P) synthesized from a mixture of free-radically polymerizable monomers (M) comprising (M1) cycloaliphatic esters of acrylic and/or methylacrylic acid; (M2) vinyl esters of aliphatic carboxylic acids; (M3) hydroxy-functional, free-radically polymerizable monomers; (M4) carboxyl-functional, free-radically polymerizable monomers and (M5) hydroxyl- and carboxyl-free (meth)acrylic esters having C1 to C12 hydrocarbon radicals in the alcohol moiety and/or vinylaromatics. The mixture further comprises glycidyl esters of aliphatic carboxylic acids. The invention also relates to a method for the production of such a dispersion, to the use of the dispersion as a coating and as a binder in 2K polyurethane coatings.
US09593253B2 Resin composition for golf balls
A golf ball resin composition includes (A) (I) an olefin-C3-8 α,β-unsaturated carboxylic acid copolymer or a metal neutralization product thereof and/or (II) an olefin-C3-8 α,β-unsaturated carboxylic acid-C3-8 α,β-unsaturated carboxylic acid ester terpolymer or a metal neutralization product thereof; (B) isocyanuric acid or a haloisocyanuric acid; and (C) a fatty acid or a fatty acid metal salt. When this resin composition is used as a cover material, the paint film adhesion between the cover material and various types of paint, including urethane-based paints, is excellent, enabling various properties of the golf ball to be improved.
US09593252B2 Ink jet recording apparatus
Provided is an ink jet recording apparatus including: a base metal pigment ink composition; and a first nozzle that ejects the base metal pigment ink composition, in which the base metal pigment ink composition contains a flat base metal pigment of which a 50% average particle diameter D50 is in a range of 100 nm to 1 μm, and an organic compound of which a surface tension at 20° C. is 35 mN/m or greater, and an ejection interval T1 after the base metal pigment ink composition is ejected from the first nozzle and before the base metal pigment ink composition is ejected again from the first nozzle is within 100 μs.
US09593251B2 Non-aqueous pigment ink
A non-aqueous pigment ink includes a pigment, a non-aqueous solvent, a non-water-soluble resin and a water-soluble resin, wherein the non-water-soluble resin is an acrylic polymer formed by a copolymer of a monomer mixture containing at least an alkyl (meth)acrylate (A) having a C8 to C18 alkyl group and a monomer (B) having a β-diketone group or β-keto acid ester group.
US09593248B2 Ink, ink cartridge, ink jet recording device, ink jet ink printed matter, compound, and composition
Ink contains at least one of a compound represented by the following chemical formula 1, a compound represented by chemical formula 2, a compound represented by chemical formula 3, or a compound represented by chemical formula 4.
US09593236B2 Preparation method of thermoplastic resin composition and thermoplastic resin composition prepared therefrom
Provided are a preparation method of a thermoplastic resin composition and a thermoplastic resin composition prepared therefrom. The preparation method includes: feeding a first thermoplastic resin in a molten state into a first hopper and feeding an impact reinforcing agent including a predetermined content of moisture into a second hopper, followed by kneading and extruding processes, and removing the moisture in a first vent port and a second vent port, wherein the first hopper, the first vent port, the second hopper, a first kneading zone, and the second vent port are sequentially formed in a moving direction of an extruder. The thermoplastic resin composition prepared therefrom can have improved appearance property and improved color property by removing moisture of an impact reinforcing agent added to the thermoplastic resin composition.
US09593235B2 Reaction product of propylene polymer and wax, graft copolymers derived from polypropylene polymer and wax, hot melt adhesive compositions including the same, and methods of using and making the same
A reaction product and hot melt adhesive compositions that include the reaction product are disclosed. The reaction product includes the reaction product of a first polymer that includes at least one of polypropylene homopolymer and polypropylene-alpha-olefin copolymer, a first wax that includes at least one of polyethylene wax, Fischer Tropsch wax and paraffin wax, and a free radical initiator and has a viscosity of no greater than 12,000 centipoise at 177° C.
US09593229B2 Polylactic acid resin composition and resin molded article thereof
A polylactic acid resin composition excellent in impact resistance, migration resistance, and heat resistance, and excellent in productivity at the time of the mold forming thereof, and a resin molded article thereof. The polylactic acid resin composition includes a polylactic acid; a reaction product of at least one selected from the group consisting of sorbitol, mannitol, and dehydration condensates thereof, an alkylene oxide mainly formed of ethylene oxide, and a fatty acid having 12 to 24 carbon atoms; and a crystal nucleating agent comprising at least one compound selected from: an organic phosphonic acid salt compound, an amide compound having a ring structure, an organic hydrazide compound, an organic sulfonic acid salt compound, a phthalocyanine compound, and a melamine compound.
US09593224B2 Porogen compositions, methods of making and uses
Provided are porogen compositions and methods of using such porogen compositions in the manufacture of porous materials, for example, porous silicone elastomers. The porogens generally include comprising a core material and shell material different from the core material. The porogens can be used to form a scaffold for making a resulting porous elastomer when the scaffold is removed.
US09593220B2 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom
There is provided herein a method of making hydroxymethylphosphonate comprising reacting paraformaldehyde, at least one dialkyl phosphite and at least one trialkyl phosphite, in the presence of at least one amine catalyst.
US09593207B2 Polyamic acid, polyimide, and method for manufacturing graphite sheet
Disclosed is a method of fabricating a graphite sheet, including: polymerizing diamines and a dianhydride to form a polyamic acid. The polyamic acid is solvent casted on a substrate and hot baked to form a polyamic acid film or gel film. The polyamic acid film or gel film is biaxially stretched at a high temperature imidization or chemical imidization to form the polyimide film. The polyimide film is then carbonized and graphitized to form a graphite sheet. The diamines include a diamine of Formula 1 and a diamine of Formula 2, and the dianhydride includes a dianhydride of Formulae 3, Formula 4, Formula 5, Formula 6, Formula 7, Formula 8, Formula 9, or combinations thereof.
US09593206B2 Aerogel insulation panels and manufacturing thereof
The present invention provides articles and methods related to insulation panels made from aerogels, and specifically polyimide based aerogels. Such insulation panels have a wide variety of applications, including specifically in aerospace applications.
US09593203B2 Metal complexes
The present invention provides novel metal complexes, methods of making, and methods of using the same.
US09593201B2 Biodegradable polymers with pendant functional groups attached through amide bonds
Amide compounds are defined and are polymerized to create polyesters and polyurethanes having amide units bearing a pendant functional group, where the nitrogen atom of the amide group is part of the polymer backbone. The pendant functional group of the functionalized amide polymer may be modified or added by post polymerization functionalization of the functionalized amide polymer. The pendant functional group of the functionalized amide polymer may include a protecting group that may be removed after polymerization. The pendant functional groups of the functionalized amide polymers may be used to modulate the physical, chemical and biological properties of the polymers.
US09593199B2 Production and use of new thermoplastic polyurethane elastomers based on polyether carbonate polyols
The invention relates to a method for producing a thermoplastic polyurethane elastomer, comprising the reaction of at least A) one organic diisocyanate containing two isocyanate groups with B) a polyol having a number-average molecular weight Mn>=500 and <=5000 g/mol, which has at least two isocyanate-reactive groups, and C) one or more chain extenders having a molecular weight >=60 and <=490 g/mol, which have two isocyanate-reactive groups, and optionally D) a monofunctional chain stopper, which has one isocyanate-reactive group, and/or E) a catalyst, wherein the molar ratio of the isocyanate groups from A) to the sum of the groups reactive to isocyanate in B), C), and, if applicable, D) is >=0.9:1 and <=1.2:1, and component B) contains at least one polyether carbonate polyol, which can be obtained by adding carbon dioxide and alkylene oxides to H-functional starter substances. The invention further relates to a thermoplastic polyurethane elastomer produced in accordance with the method according to the invention, the use of said thermoplastic polyurethane elastomer to produce extruded or injection molded items, and the items produced by extrusion or injection molding.
US09593197B2 Trigger-responsive chain-shattering polymers
Disclosed are polymers containing a backbone comprising alternating N-protected hydroxymethylaniline units (“spacer”) and linker units.
US09593196B2 Zinc(II) complex compounds as catalysts for polyurethane compositions
The present invention relates to zinc(II) complex compounds of the formula Zn(L)x(Y)2-x, wherein the ligand L has the formula (I). Such complex compounds are particularly suitable as catalysts for two-component polyurethane compositions. The invention also relates to two-component polyurethane compositions including at least one polyisocyanate as a first component, at least one polyol as a second component and at least one such zinc(II) complex compound as a catalyst. In addition, the invention relates to various uses of these two-component polyurethane compositions.
US09593192B2 Method for producing modified polymer and hydrogenated product thereof
A method for producing a modified polymer or a hydrogenated product thereof, includes polymerizing a monomer in a polymerization solvent which includes a hydrocarbon-based solvent, using a polymerization initiator to obtain a reaction solution. A functional group is introduced into the modified polymer or the hydrogenated product thereof, using a compound having the functional group protected with a silyl group. The reaction solution is separated into a solvent fraction including the hydrocarbon-based solvent, and a solid fraction including the modified polymer or the hydrogenated product thereof. The solvent fraction separated from the reaction solution is distilled to obtain a low-boiling fraction including the hydrocarbon-based solvent and a silanol compound. At least part of the silanol compound is removed from the low-boiling fraction by liquid-liquid extraction. At least part of a raffinate of the low-boiling fraction is recycled as a polymerization solvent.
US09593191B2 Use of 2-octyl acrylate polymer as a binding agent in a coating composition
The present invention relates to the use of a polymer from the polymerization of 2-octyl acrylate of renewable origin and optionally at least one other monomer, as a binding agent in or for the production of a coating composition.
US09593189B1 Pressure control to reduce pump power fluctuations
In an embodiment, a polymerization process comprises circulating, with a pump, a reaction mixture slurry in a polymerization loop reactor during a polymerization process, detecting a pressure change in the reaction mixture slurry downstream of the pump, generating, by a pressure controller, a takeoff valve actuation signal for a takeoff valve based on the pressure change, generating, by the pressure controller, a correction to the takeoff valve actuation signal, generating, by the pressure controller, a time delay for the correction, applying the correction to the takeoff valve actuation signal to generate a corrected takeoff valve actuation signal, providing the corrected takeoff valve actuation signal to the takeoff valve after the time delay, and adjusting a position of the takeoff valve in response to providing the corrected takeoff valve actuation signal. The reactor pressure is based on the takeoff valve position.
US09593188B2 Production method for solid catalyst component for polymerizing olefins, catalyst for polymerizing olefins, and production method for polymerized olefins
A method produces a novel solid catalyst component for olefin polymerization that achieves excellent olefin polymerization activity and activity with respect to hydrogen during polymerization, and can produce an olefin polymer that exhibits a high MFR, high stereoregularity, and excellent rigidity. The method includes a first step that brings a magnesium compound, a tetravalent titanium halide compound, and one or more first internal electron donor compounds into contact with each other to effect a reaction, followed by washing; a second step that brings one or more second internal electron donor compounds into contact with a product obtained by the first step to effect a reaction; and a third step that brings a tetravalent titanium halide compound and one or more third internal electron donor compounds into contact with a product obtained by the second step to effect a reaction.
US09593187B2 Chromium catalysts for olefin polymerization
Mineral oil is added to a supported chromium catalyst in amounts which maintain a free flowing particulate material. Chromium catalysts so treated, provide polyethylene in a gas phase ethylene polymerization process with reduced reactor fouling or static.
US09593183B2 Preparation method of catalyst for polymerization of polyolefin and process for polymerization of polyolefin using the same
This disclosure relates to a method for preparing a catalyst for synthesis of a polyolefin and a process for synthesis of a polyolefin using the same. More particularly, this disclosure relates to a method for preparing a catalyst for synthesis of a polyolefin including: reacting a magnesium compound with an alkane diol having a carbon number of 3 to 15 unsubstituted or substituted with an alkyl group having a carbon number of 1 to 5, and a benzoyl halide compound to prepare a magnesium compound solution; reacting the magnesium compound solution with a first transition metal compound to prepare a support; and reacting the support with a second transition metal compound to produce a solid catalyst, and a process for synthesis of a polyolefin using the same.
US09593182B2 Process of polymerization catalyst production with controlled catalyst properties and use of same in olefin polymerizations
Solid catalyst components for use in olefin polymerization, systems incorporating the same, methods of producing the same, and methods of use are disclosed. The solid catalyst components are formed by (a) dissolving a magnesium compound and an auxiliary intermediate electron donor in at least one first solvent to form a solution; (b) contacting a first titanium compound with said solution to form a precipitate of the magnesium compound and the first titanium compound; (c) washing the precipitate with a mixture of a second titanium compound and at least one second solvent and optionally an electron donor at a temperature of up to 90° C.; and (d) treating the precipitate with a mixture of a third titanium compound and at least one third solvent at 90-150° C. to form a solid catalyst component.
US09593181B2 Rubber composition for tires, and pneumatic tire using same
Provided is a rubber composition for a tire, comprising: diene rubber contained in a quantity of 100 parts by mass; silica contained in a quantity of 60 to 200 parts by mass; polysiloxanes represented by the average composition formula of Formula (1): (A)a(B)b(C)c(D)d(R1)eSiO(4-2a-b-c-d-e)/2 contained in a quantity from 1 to 20 mass % relative to the quantity of silica; and a thiuram disulfide vulcanization accelerator contained in a quantity from 0.05 to 3.0 parts by mass.
US09593179B2 Amorphous propylene-ethylene copolymers
Amorphous propylene-ethylene copolymers are described herein that can include high amounts of ethylene and exhibit desirable softening points and needle penetrations. The desirable combinations of softening points and needle penetrations in these propylene-ethylene copolymers allow them to have a broad operating window. Due their broad operating window, the propylene-ethylene copolymers can be utilized in a wide array of applications and products, including hot melt adhesives.
US09593178B2 Pre-polymerized catalyst components for the polymerization of olefins
A pre-polymerized catalyst component for the polymerization of olefins endowed with high activity and morphological stability comprises a non-stereospecific solid catalyst component containing Ti, Mg and a halogen, and an amount of an ethylene/alpha-olefin block (co)polymer ranging from 0.1 up to 5 g per g of said solid catalyst component, said prepolymerized catalyst component being characterized by a mercury porosity, due to pores having radius up to 1 μm, ranging from 0.15 to 0.5 cm3/g and by the fact that at least 55% of said porosity is due to pores having pore radius up to 0.2 μm.
US09593177B2 Polyethylene
The present invention relates to a low density polyethylene having a molecular weight distribution Mw/Mn which is greater than 15, a storage modulus G′ (5 kPa) which is above 3000 and a vinylidene content which is at least 15/100 k C, compositions, a process for production of the low density polyethylene, a continuous ethylene polymerization method for introducing vinylidene in a low density polyethylene, a method for an extrusion coating process, an article, e.g. an extrusion article, and use in extrusion coating.
US09593175B2 Solid titanium catalyst component for ethylene polymerization, ethylene polymerization catalyst and ethylene polymerization method
Provided are a solid titanium catalyst component for ethylene polymerization which can polymerize ethylene at a high activity and which can provide an ethylene polymer having an excellent particle property, an ethylene polymerization catalyst and an ethylene polymerization method in which the catalyst is used.The solid titanium catalyst component (I) for ethylene polymerization according to the present invention is obtained by bringing a liquid magnesium compound (A) including a magnesium compound, an electron donor (a) having 1 to 5 carbon atoms and an electron donor (b) having 6 to 30 carbon atoms into contact with a liquid titanium compound (C) under the presence of an electron donor (B) and includes titanium, magnesium and a halogen. The ethylene polymerization catalyst of the present invention includes the component (I) and an organic metal compound catalyst component (II). Further, the ethylene polymerization method of the present invention is a method for polymerizing ethylene under the presence of the catalyst.
US09593174B2 Acetoacetyl group-containing polyvinyl alcohol resin powder composition, and production method therefor
Acetoacetyl group-containing polyvinyl alcohol resin powder composition containing a C1 to C3 alcohol in an amount of 0.5 to 4 wt % is produced by allowing a powdery polyvinyl alcohol resin to react with diketene, washing the resulting acetoacetyl group-containing polyvinyl alcohol resin particles with the C1 to C3 alcohol to remove an unreacted portion of the diketene, and drying the intermediate acetoacetyl group-containing polyvinyl alcohol resin particles composition at a temperature of 40° C. to 120° C. at a pressure of not higher than 20 kPa after the washing. The acetoacetyl group-containing polyvinyl alcohol resin powder composition thus produced is highly soluble in water.
US09593163B2 Oncostatin M receptor antigen binding proteins
The invention provides anti-oncostatin M receptor-β (OSMR) antigen binding proteins, e.g., antibodies and functional fragments, derivatives, muteins, and variants thereof. OSMR antigen binding proteins interfere with binding of OSM and/or IL-31 to OSMR. In some embodiments, anti-OSMR antigen binding proteins are useful tools in studying diseases and disorders associated with OSMR and are particularly useful in methods of treating diseases and disorders associated with OSMR and binding of OSM and/or IL-31 to OSMR.
US09593159B2 Human binding molecules capable of neutralizing influenza A viruses of phylogenetic group 1 and phylogenetic group 2 and influenza B viruses
Described are binding molecules, such as human monoclonal antibodies, that bind to an epitope in the stem region of hemagglutinin of influenza A viruses of phylogenetic group 1 and group 2, as well as influenza B viruses, and have a broad neutralizing activity against such influenza viruses. Provided are nucleic acid molecules encoding the binding molecules, their sequences, and compositions comprising the binding molecules. The binding molecules can be used, for example, in the diagnosis, prophylaxis, and/or treatment of influenza A viruses of phylogenetic groups 1 and 2, as well as influenza B viruses.
US09593158B2 Process for the preparation of gelatin
The present invention relates to a process for preparing gelatin comprising a step of incubating a material comprising collagen with an enzyme composition comprising an acid protease which has at least 70% identity to the amino acid sequence of SEQ ID NO:1, and preparing the gelatin. The invention also relates to gelatin obtained by a process as disclosed herein.
US09593157B2 Chimeric polypeptides comprising G protein-coupled receptors and VHH antibodies
Described are polypeptides and their use for screening and drug discovery. More specifically, the disclosure provides chimeric polypeptides comprising a membrane protein, in particular a GPCR, fused to a binding domain, wherein the binding domain is directed against and/or specifically binds to the membrane protein. In particular, the chimeric polypeptides are single proteins wherein, in an intramolecular reaction, the binding domain stabilizes the membrane protein in a conformation of interest. Also provided are nucleic acid sequences encoding such chimeric polypeptides, cells capable of expressing such chimeric polypeptides as well as cellular compositions derived thereof. Also screening methods for compounds using the chimeric polypeptides.
US09593153B2 Modified apelin polypeptides
The present invention relates to polypeptides and their uses as apelin inhibitors. More particularly, the present invention relates to a polypeptide comprising the sequence as set forth in SEQ ID NO:1 wherein at least one arginine residue at position 18, 19, 22 or 23 has been substituted or deleted.
US09593149B2 Amylin and calcitonin receptor agonist
The present invention relates to peptides comprising an amino acid sequence SEQ ID NO: 1 (EASELSTAALGRLSAELHELATLPRTETGPESP), analogs and derivatives thereof and pharmaceutical compositions comprising such peptides and derivatives. This invention further regards the use of these peptides according to SEQ ID NO: 1, analogs and derivatives thereof as medicaments.
US09593148B2 DPP8 and DPP9 peptide inhibitors
The present invention relates to non-competitive allosteric peptide inhibitors of DPP9 and/or DPP8, competitive peptides binding to SUMO1, nucleic acid molecules and expression vectors coding said peptide inhibitors, host cells expressing said inhibitors, kits comprising said inhibitors, as well as methods of producing said inhibitors, and uses of said peptide inhibitors; as further defined in the Claims.
US09593144B2 FPR1 antagonist derivatives and use thereof
A dipeptide derivative as formyl peptide receptor 1 (FPR1) antagonist is provided. The dipeptide derivative is represented by formula (I), wherein: the chiral centers in formula (I) are S and R configurations respectively; each of RK and RT is selected from a group consisting of a hydrogen, a hydroxyl group, a C1-C4 alkyl-substituted hydroxyl group, a C1-C4 alkoxyl group, a carboxylic acid group, a C1-C4 alkyl nitrile-substituted, C1-C4 alkyl-substituted or C1-C4 alkoxyl-substituted amido group, a C1-C4 alkyl-substituted ester group and a benzoyl group having a C1-C4 alkyl-substituted benzene ring; and each of RM and RS is selected from a group consisting of a hydrogen, a hydroxyl group, a phenyl group, a pyridinyl group, a carboxylic acid group, a C1-C4 alkoxyl substituted ester group, and a benzoyl group having a hydroxyl-substituted, a halogen-substituted, a C1-C4 alkoxyl-substituted or a C1-C4 alkyl-substituted benzene ring.
US09593137B2 Guanine analogs as telomerase substrates and telomere length affectors
This invention relates to compounds useful for inhibiting telomere elongation. More specifically, the invention provides nucleotide analogs that are incorporated into telomeres by telomerase thereby inhibiting elongation of telomeres. The compounds are useful in treating cancer and other cell proliferative diseases.
US09593135B2 Compositions comprising alkoxysilane-containing isocyanates and acid stabilisers
The present invention relates to a composition comprising (A) an isocyanate of formula (I) OCN-A-SiR1R2R3 (I), wherein A is straight-chain, branched, substituted and/or unsubstituted aliphatic hydrocarbyl of 1 to 12 carbon atoms or substituted or unsubstituted cycloaliphatic hydrocarbyl of 4 to 18 carbon atoms, wherein R1 is selected from the group comprising —O—Ralk, wherein R2 and R3 are each independently selected from the group of substituents comprising —Ralk and —O—Ralk, and wherein —Ralk is hydrocarbyl of 1 to 6 carbon atoms, and B) a Bronstedt or Lewis acid or a compound which releases a Bronstedt or Lewis acid at room temperature; and also to a process for producing a stabilized alkoxysilane-containing isocyanate comprising the step of adding a Lewis or Bronstedt acid or a compound which releases a Bronstedt or Lewis acid at room temperature to an alkoxysilane-containing isocyanate.
US09593129B2 Piperidinone derivatives as MDM2 inhibitors for the treatment of cancer
The present invention provides MDM2 inhibitor compounds of Formula I, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.
US09593128B2 Tetrazole-substituted arylamides as P2X3 and P2X2/3 antagonists
Compounds of the formula V: or a pharmaceutically acceptable salt thereof, wherein, R2 is optionally substituted phenyl, optionally substituted pyridin-2-yl or optionally substituted thienyl, and R3, R4, R5, R6 and R13 are as defined herein. Also provided are methods of using the compounds for treating diseases associated with the P2X3 and/or a P2X2/3 receptor antagonist and methods of making the compounds.
US09593124B2 Transition metal-catalyzed processes for the preparation of N-allyl compounds and use thereof
The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine.
US09593119B2 Process for the preparation of dipeptidylpeptidase inhibitors
The present invention provides a process for the preparation of linagliptin, a compound of Formula I, the process comprising deprotecting a compound of Formula II wherein R1 and R2 together with the nitrogen to which they are attached form a phthalimido group, wherein the aromatic ring of the phthalimido group is substituted with one or more R3 substituents selected from the group consisting of halogen, alkyl, nitro and amino; or R1 is H and R2 is selected from the group consisting of trialkylsilyl, 2-trialkylsilylethoxycarbamates, acetyl, trihaloacetyl, 9-fluorenylmethoxycarbonyl, trityl, alkylsulfonyl, arylsulfonyl, diphenylphosphine and sulfonylethoxycarbonyl.
US09593117B2 Crystalline form of N,N-dicyclopropyl-4-(1,5-dimethyl-1H-pyrazol-3-ylamino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide for the treatment of myeloproliferative disorders
Crystalline form, Form HI.5-4, of N,N-di-cyclopropyl-4-(1,5-dimethyl-1H-pyrazol-3-ylamino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide, (Compound I) is provided. Also provided are a pharmaceutical composition and an oral dosage form comprising Form HI.5-4 of Compound I as well as a method of using the Form HI.5-4 of Compound I in the treatment of myeloproliferative disorders, which include polycythaemia vera, thrombocythaemia and primary myelofibrosis.
US09593116B2 Crystalline forms of N,N-dicyclopropyl-4-(1,5-dimethyl-1H-pyrazol-3-ylamino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide for the treatment of myeloproliferative disorders
Crystalline form, Form T1H1.5-4, of N,N-dicyclopropyl-4-(1,5-dimethyl-1H-pyrazol-3-ylamino)-6-ethyl-1-methyl -1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide (Compound (I)) is provided. Also provided is a pharmaceutical composition and an oral dosage form comprising Form T1H1.5-4 of Compound (I) as well as a method of using the Form T1H1.5-4 of Compound for the treatment of myeloproliferative disorders, which include polycythaemia vera, thrombocythaemia and primary myelofibrosis.
US09593113B2 Imide and acylurea derivatives as modulators of the glucocorticoid receptor
Novel non-steroidal compounds are provided which are useful in treating diseases or disorders associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-KB activity, including metabolic and inflammatory and immune diseases or disorders, having the structure of formula (I): an enantiomer, diastereomer, or tautomer thereof, or a pharmaceutically-acceptable salt thereof, in which the variables are as defined in the specification.
US09593104B2 Process for the preparation of oxazolidinone derivatives
The present invention relates to an improved process for the preparation of Oxazolidinone derivatives. More specifically, the present invention relates to an improved process for preparing (S)-N-[[3-[3-fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]phthalimide, an intermediate used in the preparation of Oxazolidinone derivatives.
US09593101B2 Avanafil preparation method
Disclosed is a method for preparing avanafil (I) by using cytosine as the starting material. The preparation steps comprise: using cytosine as the raw material, and enabling the cytosine to react with side chain 3-chlorine-4-methoxybenzyl halogen, N-(2-methylpyrimidine)methanamide and S-hydroxymethyl pyrrolidine, to prepare the target product avanafil (I). For the preparation method, the raw material is easily obtained, and the process is simple, economical, and environmentally friendly, so the method meets the requirement of industrial boost.
US09593099B2 Compounds and compositions as protein kinase inhibitors
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
US09593098B2 Compounds and compositions for modulating EGFR mutant kinase activities
The present invention provides a new group of protein kinase inhibitors, aminopyrimidine derivatives, and pharmaceutically acceptable salts thereof that are useful for treating cell proliferative disease and disorder such as cancer and immune disease. The present invention provides methods for synthesizing and administering the protein kinase inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the protein kinase inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefore. The invention also provides useful intermediates generated during the syntheses of the aminopyrimidine derivatives.
US09593095B2 Methods for the treatment of bacterial infections
This invention relates generally to the discovery of a method of inhibiting, preventing or treating bacterial infections. The invention also relates to a method of inhibiting bacterial capsule biogenesis.
US09593094B2 Liquid crystal medium, optical device, and liquid crystal compound
A liquid crystal medium having stability to heat, light and so forth, a wide liquid crystal phase temperature range, a low driving voltage and a small permittivity and exhibiting an optically isotropic liquid crystal phase is described. An optical device or the like having a short response time, a large contrast ratio, a low driving voltage and a small permittivity is also described. The liquid crystal composition contains an achiral component (T) and a chiral agent, and exhibits an optically isotropic liquid crystal phase. The achiral component (T) includes at least one compound represented by formula (1): wherein, for example, R1 is alkyl having 1 to 12 carbons, A1 and A2 are 1,4-phenylene, Z1 and Z2 are single bonds, Z3 is —COO— or —CF2O—, L11 is hydrogen, fluorine or chlorine, Y1 is fluorine, chlorine, —CF3 or —OCF3, n1 and n2 are each independently 0 or 1, and n1+n2≧1.
US09593093B2 Methods for the manufacture of acetals and ketals, and the acetals and ketals produced thereby
A method for producing a product that comprises glycerol ketal of ethyl levulinate or propylene glycol ketal of ethyl levulinate comprises reacting either glycerol or propylene glycol with ethyl levulinate in the presence of a homogenous or heterogeneous catalyst system in a reactor system. The ethyl levulinate and either glycerol or propylene glycol are heated to remove water, polyol, and excess ethyl levulinate. The excess ethyl levulinate and polyol is recycled back to the reactor. The product is distilled in a specific fashion and optionally treated by means of a stabilizing agent or acid species removal bed, to obtain a composition comprising glycerol ketal of ethyl levulinate or propylene glycol ketal of ethyl levulinate wherein the composition comprises less than or equal to about 2 wt % contaminants.
US09593090B2 Alkylene oxide separation systems, methods, and apparatuses
A propylene oxide separation system that comprises a distillation column, a decanter, and water wash system. The distillation column is configured to receive a crude propylene oxide stream, discharge an impurity stream that comprises methanol and water, and discharge a bottoms stream that comprises a majority of the propylene oxide entering in the crude propylene oxide stream. The decanter is configured to receive at least a portion of the impurity stream and a hydrocarbon solvent to provide for formation in the decanter of an organic phase and an aqueous phase. The organic phase comprises propylene oxide and hydrocarbon solvent, and is sent to the distillation column. The aqueous phase comprises a majority weight percent of the methanol and the water entering in the impurity stream. The water wash system is configured to receive and purge the aqueous phase from the propylene oxide separation system.
US09593089B2 Process for preparing TDI isocyanurate
The present invention relates to a method for preparing TDI (toluene diisocyanate) isocyanurate by using TDI, monohydric alcohol, solvent, antioxidant, catalyst and termination agent as the raw materials. The properties of the isocyanurate are improved by the process comprising the modification by monohydric alcohol and addition of the catalyst and solvent in several stages at an appropriate temperature. By adding the catalyst and solvent in batches at the condition of controlling both NCO % and the viscosity in the preparation process, and adjusting the solid content at each step, the resulting TDI isocyanurate has low content of free TDI, high xylene tolerance, small product color number, and high performance stability, which makes the product obtained by the isocyanurate have good application properties such as the drying, polishing and extinction properties of coating film, and such isocyanurate has good compatibility with other components.
US09593087B2 Materials for organic electroluminescent devices
The present invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic devices which comprise these compounds.
US09593084B2 Chloro-pyrazine carboxamide derivatives with epithelial sodium channel blocking activity
This invention provides compounds of the formula I: and their pharmaceutically acceptable salts, useful as sodium channel blockers, compositions containing the same, therapeutic methods and uses for the same and processes for preparing the same.
US09593083B2 Crystalline erlotinib hydrochloride process
The present invention provides process for preparation of Crystalline Erlotinib HCl (I) Form-SE characterized by X-ray powder diffraction pattern comprising at least 5 characteristic 2θ° peaks selected from the XRPD peak set of 5.60, 10.00, 11.40, 13.00, 13.50, 15.20, 18.40, 20.65, 21.86, 23.5, 31.80, 32.13, 32.80, 34.40±0.20 2θ°, DSC isotherm comprising the endothermic peaks ranging between 213 to 217° C. (Peak −1) and 225 to 235° C. (Peak −2) and IR absorption characteristic peaks at approximately 3278 cm−1, 1948 cm−1, 1871 cm−1, 1632 cm−1, 1164 cm−1, 1024 cm−1, 940 cm−1 and 742 cm−1 useful as active pharmaceutical ingredient in pharmaceutical compositions for the treatment cancer.
US09593079B2 Stabilized multi-functional antioxidant compounds and methods of use
Disclosed are novel stable compounds having anti-oxidant properties and methods of using the compounds for the treatment of diseases or injuries associated with oxidative stress.
US09593078B2 Crystal forms
The present invention features crystalline forms of Compound I. In one embodiment, a crystalline form of Compound I has characteristic peaks in the PXRD pattern as shown in one of FIGS. 1-10.
US09593073B2 Method for the preparation of diazoalkanes
The present invention relates to a method of forming diazoalkanes. One aspect of the present invention provides a method for the production of a N-alkyl-N-nitroso compound from a starting material, comprising the use of a tribasic acid to acidify an amine. A second aspect of the present invention provides a method for the production of a diazoalkane, comprising reacting a N-alkyl-N-nitroso compound with a base and a phase transfer catalyst, wherein no organic solvent is used.
US09593072B2 Process for preparing N-acyl amino acid salts
N-Acyl amino acid salt compositions and an improved process for making them from fatty alkyl esters are disclosed. The process comprises reacting a fatty alkyl ester with an amino acid salt in the presence of an alkoxide catalyst at a pressure of at least 5 psig. At least 10 mole percent of catalyst is used based on the amount of fatty alkyl ester used as a reactant. Pressure and a minimum level of alkoxide catalyst are needed to give high fatty alkyl ester conversions and good yields of the desired N-acyl amino acid salt. The resulting N-acyl amino acid salt compositions have low color, an acceptable level of fatty acid soaps, and a small proportion of di-acylated by-products. Single-phase mixtures produced by combining various amino acid salts with glycinates, or by using an excess of either the fatty alkyl ester or amino acid salt, promote high conversions when the mixtures are reacted to give the desired N-acyl amino acid salt.
US09593067B2 Method for recovering intracellular components from fermented microorganisms
The present invention relates to a method for the recovery of intracellular components of materials of a biological origin, such as yeasts, algae, bacteria and/or mildews, after fermentation/cultivation, which comprises a thermal lysing treatment via nebulization and the use of a nebulization solvent capable of extracting said intracellular components once the nebulization has been completed.
US09593064B2 Conversion of alcohols to alkyl esters and carboxylic acids using heterogeneous palladium-based catalysts
Disclosed are methods for synthesizing an ester or a carboxylic acid from an organic alcohol. To form the ester one reacts, in the presence of oxygen gas, the alcohol with methanol or ethanol. This reaction occurs in the presence of a catalyst comprising palladium and a co-catalyst comprising bismuth, tellurium, lead, cerium, titanium, zinc and/or niobium (most preferably at least bismuth and tellurium). Alternatively that catalyst can be used to generate an acid from that alcohol, when water is also added to the reaction mix.
US09593062B2 Means and methods for treating and/or preventing natural AHR ligand-dependent cancer
The present invention relates to the field of cancer therapeutics and treatment of cancer. In particular, it relates to a method for treating and/or preventing a natural AHR ligand-dependent cancer comprising administering to a subject suffering from said cancer a therapeutically effective amount of an AHR inhibitor. Moreover, contemplated is a AHR inhibitor for use in treating and/or preventing a natural AHR ligand-dependent cancer.
US09593061B2 Synthesis of intermediates for producing prostacyclin derivatives
The present disclosure provides regioselective methods for synthesizing intermediates useful in making prostacyclin derivatives, such as treprostinil.
US09593058B2 Method for producing 1,1-dibromo-1-fluoroethane
An object of the present invention is to provide a production method that makes it possible to produce 1,1-dibromo-1-fluoroethane easily and sustainably.The present invention provides a method for producing 1,1-dibromo-1-fluoroethane, the method comprising step A of reacting 1,1-dibromoethylene with hydrogen fluoride to obtain 1,1-dibromo-1-fluoroethane.
US09593055B2 Method for preparing linear alpha-olefins
The present invention relates to a method for preparing linear alpha-olefins (LAO) by oligomerization of ethylene in the presence of solvent and homogenous catalyst, comprising the steps of: (i) feeding ethylene, solvent and catalyst into an oligomerization reactor, (ii) oligomerizing the ethylene in the reactor, (iii) removing a reactor outlet stream comprising solvent, linear alpha-olefins, ethylene, and catalyst from the reactor via a reactor outlet piping system, (iv) transferring the reactor outlet stream to a catalyst deactivation and removal step, and (v) deactivating and removing the catalyst from the reactor outlet stream, characterized in that at least one organic amine is added into the oligomerization reactor and/or into the reactor outlet piping system.
US09593053B1 Photoelectrosynthetically active heterostructures
A two-step process, consisting of a photoelectrosynthetic process combined with a thermochemical process, is configured to produce a reduction product (e.g., methane gas, methanol, or carbon monoxide) from carbon dioxide and liquid waste streams. In a first step, photoelectrosynthetically active heterostructures (PAHs) and sunlight are used to drive oxidation/reduction reactions in which one primary product is hydrogen gas. In the second step, hydrogen generated in the first step is thermally catalytically reacted with carbon dioxide to form a reduction product from carbon dioxide (e.g., CO, formaldehyde, methane, or methanol). Synthesis gas (CO and H2) can be further reacted to form alkanes. The methods and systems may employ PAHs known in the art or improved PAHs having lower costs, improved stability, solar energy conversion efficiency, and/or other desired attributes as disclosed herein.
US09593051B2 Coating systems for cement composite articles
A method for making a coating composition by mixing one or more latex polymers and an aliphatic epoxy resin system having an epoxy equivalent weight less than 1000 and being distinct from the one or more latex polymers to provide an aqueous first component, and providing a second component having reactive groups that can react with the one or more epoxy resins. A mixture of the first and second components provides a film-forming curable coating composition that may be used on substrates including cement, cement fiberboard, wood, metal, plastic, ceramic, glass and composites.
US09593050B2 System, method and apparatus for entraining air in concrete
A method of preparing a concrete composition for downhole injection includes utilizing a controller to control a process including circulating process water in a process water supply loop for a predetermined period while monitoring and controlling the temperature and flow rate of the process water, circulating aqueous-based air entrainment solution in an aqueous-based air entrainment solution supply loop for the predetermined period and controlling the flow rate of the aqueous-based air entrainment solution and after the predetermined period of time in which the flow of process water and aqueous-based air entrainment solution have stabilized, simultaneously actuating valves to divert and mix the process water, the aqueous-based air entrainment solution and compressed air to produce an air-entrained foam and mixing the foam with a concrete composition to be deployed downhole.
US09593049B2 Method for incorporating refractory metal element into ceramic matrix composite
A method of forming a ceramic matrix composite are described herein. The method may include infiltrating a fiber preform with a solution comprising a refractory precursor in solution with a solvent. The refractory precursor may include a compound having at least one refractory metal element. The method may further include removing the solvent from the fiber preform, and reducing the refractory precursor to form a refractory metal that includes the refractory metal element.
US09593041B2 Transparent composite material and a production method therefor
A colorless composite material according to an embodiment includes glass fibers, and inorganic-organic hybrid resin having inorganic bonds and organic bonds, wherein the inorganic bonds are M-O-M bonds and M denotes a metallic element, wherein the metallic element is one of Ti, Zr and Al.
US09593040B2 Non-opaque arsenic-free beta-spodumene glass ceramic exhibiting brown-grey coloration
Methods, compositions, and articles provide for LAS-type glass-ceramics having specific thermo-mechanical, optical and coloration characteristics to yield generally brown-grey products. The glass-ceramic materials may include as colorants iron oxide, vanadium oxide, chromium oxide, cobalt oxide, nickel oxide and/or cerium oxide.
US09593038B2 Glass compositions and fibers made therefrom
Embodiments of the present invention provides fiberizable glass compositions formed from batch compositions comprising amounts of one or more glassy minerals, including perlite and/or pumice.
US09593036B2 Methods and apparatuses for forming optical preforms from glass soot
Methods and apparatuses for forming optical preforms from silica glass soot are disclosed. According to one embodiment, a method for forming an optical preform may include loading silica glass soot in a mold cavity of a mold body. The mold body may be rotated at a rotational speed sufficient to force the silica glass soot towards an inner wall of the mold body. Thereafter the silica glass soot is compressed in an inward radial direction as the mold body is rotated to form a soot compact layer.
US09593030B2 Liquid treatment apparatus and liquid treatment method
A liquid treatment apparatus includes a dielectric tube through which water to be treated flows, a first electrode at least a part of which is disposed in the dielectric tube, a second electrode at least a part of which is disposed in the dielectric tube at a position upstream of the first electrode, a gas supplier operative to generate a bubble by supplying a gas into the water to be treated, and a power supply operative to apply a voltage between the first electrode and the second electrode in a state in which the bubble covers a conductor-exposed portion of the first electrode.
US09593025B2 Wastewater evaporator
The wastewater evaporator provides for effluent evaporation in a septic system to eliminate need for a drain field. The evaporator tank contains a plurality of evaporator trays in a vertical array. Solids settle in the septic tank, and liquid effluent flows from the septic tank to the evaporator tank and cascades sequentially from the uppermost to the lowermost tray. The multiple trays increase the surface area of liquid contained therein, thereby greatly enhancing evaporation. An above-surface air pump and vent may be provided for air flow through the evaporator tank. An ultrasonic generator may be installed in each tray to increase the surface area of the effluent to enhance evaporation. An additional intermediate pump tank may be provided between the septic tank and the evaporator tank to control effluent flow and delivery to the evaporator tank. A sump pump in the pump tank periodically delivers effluent to the evaporator tank.
US09593023B2 Process for treating a sodium carbonate purge
A method for treating a purge stream derived from a sodium carbonate, sesquicarbonate, wegsheiderite, or bicarbonate crystallizer,said purge stream comprising sodium carbonate and/or sodium bicarbonate and at least 1% by weight of sodium chloride and/or sodium sulfate,the method comprising: causticizing at least 50 mol. % of the sodium from sodium carbonate and/or sodium bicarbonate into a caustic solution and into a calcium carbonate mud with lime and water, separating the calcium carbonate mud from the caustic solution; concentrating the caustic solution by removing part of the water to obtain a concentrated caustic solution comprising at least 25% NaOH, and a crystallized solid comprising sodium carbonate and sodium chloride and/or sulfate, separating the crystallized solid from the concentrated caustic solution, said crystallized solid to be disposed of or to be further valorized, recycling part of the concentrated caustic solution to the sodium carbonate, sesquicarbonate, wegsheiderite, or bicarbonate crystallizer.
US09593021B2 Method for processing finely divided solids during production of chlorosilanes
The invention provides a method for the processing of finely divided solids during the production of chlorosilanes, which is characterized in that the finely divided solids are hydraulically pressed to give bodies of increased density. Moreover, also provided is the compact obtained by the process according to the invention which is characterized by a filling factor of the finely divided solids to be hydraulically pressed of 3.9 to 4.5.
US09593016B2 Method for producing difluorophosphate, non-aqueous electrolyte for secondary cell and non-aqueous electrolyte secondary cell
A difluorophosphate effective as an additive for a nonaqueous electrolyte for secondary battery is produced by a simple method from inexpensive common materials.The difluorophosphate is produced by reacting lithium hexafluorophosphate with a carbonate in a nonaqueous solvent. The liquid reaction mixture resulting from this reaction is supplied for providing the difluorophosphate in a nonaqueous electrolyte comprising a nonaqueous solvent which contains at least a hexafluorophosphate as an electrolyte lithium salt and further contains a difluorophosphate. Also provided is a nonaqueous-electrolyte secondary battery employing this nonaqueous electrolyte.
US09593015B2 Sulfur recovery process for treating low to medium mole percent hydrogen sulfide gas feeds with BTEX in a Claus unit
An enrichment apparatus and process for enriching a hydrogen sulfide concentration in an acid gas stream to create a hydrogen sulfide rich stream for feed to a Claus. The enrichment apparatus comprises a hydrocarbon selective separation unit operable to separate the acid gas stream into a hydrocarbon rich stream and a purified acid gas stream, wherein the acid gas stream comprises hydrogen sulfide, carbon dioxide, and hydrocarbons, a hydrogen sulfide selective separation unit operable to separate the purified acid gas stream to create the hydrogen sulfide rich stream and a hydrogen sulfide lean stream, the hydrogen sulfide rich stream having a concentration of hydrogen sulfide, and the Claus unit operable to recover sulfur from the carbon dioxide lean stream. The enrichment apparatus can include a carbon dioxide selective separation unit in fluid communication with the hydrogen sulfide selective separation unit, operable to separate the hydrogen sulfide rich stream.
US09593011B2 Micromechanical component and method for producing a micromechanical component
A method is described for producing a micromechanical component. The method includes providing a first substrate, providing a second substrate, developing a projecting patterned element on the second substrate, and connecting the first and the second substrate via the projecting patterned element. The method provides that the connecting of the first and the second substrate includes eutectic bonding. Also described is a micromechanical component, in which a first and a second substrate are connected to each other.
US09593009B2 Apparatus comprising and a method for manufacturing an embedded MEMS device
A system and a method for forming a packaged MEMS device are disclosed. In one embodiment a packaged MEMS device includes a MEMS device having a first main surface with a first area along a first direction and a second direction, a membrane disposed on the first main surface of the MEMS device and a backplate adjacent to the membrane. The packaged MEMS device further includes an encapsulation material that encapsulates the MEMS device and that defines a back volume, the back volume having a second area along the first direction and the second direction, wherein the first area is smaller than the second area.
US09593002B2 Work vehicle, and control method for work vehicle
A work vehicle includes an accelerator operation amount generator receiving an actual accelerator operation amount of an accelerator operator to generate a control accelerator operation amount; an engine controller controlling the engine according to the control accelerator operation amount; and a storage storing a table in which an increasing speed for the control accelerator operation amount is set, wherein the accelerator operation amount generator obtains a difference between a converted accelerator operation amount of the accelerator operator converted from a rotating speed of the engine in a current control cycle and a control accelerator operation amount obtained in the last control cycle, determines an increasing speed of the control accelerator operation amount from the difference by referring to the table, and changes the control accelerator operation amount to an actual operation amount in the current control cycle with the determined increasing speed.
US09593001B2 Mechanism for translation/rotation in X-Y directions
A mechanism is disclosed for controlling the position of a heavy object, such as a part of a vehicle, in an x, y, z coordinate plane. The mechanism includes linear positioners, such as rail-guided carriage assemblies spanning the width of the mechanism, as well as longitudinal rails and blocks running the length of the mechanism. A lift table is mounted to the linear positioners such that the mechanism can be used to move the heavy object to virtually any desired position and orientation in the x, y, z coordinate plane.
US09592998B2 Apparatus for transporting commercial and industrial appliance units
Disclosed are various embodiments of an apparatus for raising, suspending, transporting, and lowering appliance units for installation and removal. Two support frame assemblies, each having telescopic legs attached to wheels and upper support brackets from which the appliance unit is suspended, are connected by a removable frame connector. The apparatus may then be rolled across a rooftop to move and place the appliance unit. The frame connector may be replaced with a retention connector and supplemented with a lower retention connector for efficient storage and transport of the apparatus.
US09592990B2 Informational item forming method
A method of using a folding apparatus to form an outsert having product information printed thereon comprises applying a plurality of parallel lines of water to a sheet of paper using a plurality of spray nozzles and being applied at positions at which folds are to be made; making a plurality of folds in a first direction in the sheet of paper with a first folding apparatus; making a plurality of folds in a second direction perpendicular to the first direction; and making a fold in in the second direction to form an outsert including causing a movable member of a folding apparatus to make contact with and move a folded article towards a folding roller, and so that the folded article makes contact with the folding roller to form a fold in the folded article.
US09592989B2 High speed multi-bin card collation system
An automated high speed multi-bin card collation system that takes die cut greeting cards at high speeds and diverts them on a customer by customer basis into multiple bins. A series of diverters are included that actuate between customer jobs to divert and collate the jobs independently into the bins. Each bin has a retractable floor that allows the individualized jobs to be collated prior to dropping onto a conveyor system. The conveyor then conveys the collated card jobs to a downstream location.
US09592984B2 Image forming apparatus with a conveyance section movable in a width direction
An image forming apparatus includes: a first conveyance section disposed on an upstream side of the image formation position in a sheet conveyance direction of the long sheet, and configured to convey the long sheet to the image formation position; a second conveyance section disposed on a downstream side of the image formation position in the sheet conveyance direction, and configured to convey the long sheet on which the toner image is formed; a displacement detection section configured to detect displacement of the long sheet in a sheet width direction; and a control section configured to move the first conveyance section in the sheet width direction to orient the long sheet in the sheet width direction, and move the second conveyance section in a direction identical to a direction along which the first conveyance section is moved based on a detection result of the displacement detection section.
US09592983B2 Missort prevention system in a conveying system
A missort prevention system prevents missorts in a sortation conveying system. The missort prevention system includes a sensor for detecting the presence of an unexpected article on a chute transitioning articles off of a conveyor and a missort preventer for blocking the further passage of the unexpected article on the chute.
US09592982B2 Medium detection mechanism, medium detection method, and printing apparatus
A medium detection mechanism includes a medium guide that holds a medium and an optical sensor including an irradiation section that emits irradiation light to the medium guide and a light receiving section that receives reflected light. An amount of received light that is received by the light receiving section from among reflected light of external light that enters the medium guide and reflected light of the irradiation light is smaller than or equal to a predetermined value.
US09592980B2 Paper conveying apparatus, jam detection method, and computer-readable, non-transitory medium
There is provided the paper conveying apparatus, jam determining method, and computer program, which can suppress the mistaken determining of the occurrence of a jam by sound due to a sound generated by a moving member driven in relation to conveyance of a paper. The paper conveying apparatus according to an embodiment includes a moving member driven in relation to conveyance of a paper, a drive module for driving the moving member, a sound signal generator for generating a sound signal corresponding to a sound generated by a paper during conveyance of the paper, a sound jam detector for determining whether a jam has occurred based on the sound signal, and a control module for stopping conveyance of a paper when the sound jam detector determines that a jam has occurred. The control module controls so that the sound jam detector determines whether a jam has occurred by a determining method different from a determining method used while the drive module is not driving the moving member, or the sound jam detector does not determine whether a jam has occurred, while the drive module is driving the moving member.
US09592978B2 Medium protection device and medium separating and stacking device
The present invention provides a medium protection device and a medium separating and stacking device capable of avoiding damage to a medium when moving the medium along a guide. In a banknote cassette, a guide body is attached to a circumferential side face of a central body of a tongue piece roller in a range not provided with tongue pieces. When feeding out banknotes, the banknote cassette stops the tongue piece roller in a retracted state, thereby positioning an outer circumferential face of the guide body in the vicinity of the surface of a front upper curved portion of a hole in the conveyance guide, such that the hole can be placed in an almost completely blocked state. The present invention can accordingly prevent the vicinity of a corner of a banknote from entering the hole, enabling creasing during conveyance to be forestalled.
US09592973B2 Sheet feeding apparatus and image forming apparatus
A sheet feeding apparatus includes a stacking portion, a lifting portion, a feeding portion, and a control portion. The sheet feeding apparatus further includes a first height detecting portion configured to output a signal corresponding to a position in a height direction of the topmost sheet of sheets stacked on the stacking portion, a sheet presence detecting portion configured to output a signal corresponding to presence or absence of the sheets stacked on the stacking portion, and a second height detecting portion configured to output a signal corresponding to a position in a height direction of the stacking portion. The control portion performs control for sheet feeding operation using the signal from the sheet presence detecting portion if the position of the stacking portion is above a predetermined height based on the signal from the second height detecting portion and, if the position of the stacking portion is below the predetermined height, the control portion performs control for sheet feeding operation not using the sheet presence detecting portion.
US09592971B2 Pick and bond method and apparatus for attachment of adhesive element to substrate
A method and apparatus for transferring formed adhesive elements from a reservoir (30) containing plural formed adhesive elements (12) to a bonding part attachable to a glass surface or other substrate through the use of adhesives. Transfer of the formed adhesive element to the bonding part (14) is accomplished by use of a vacuum tool (10) having a vacuum outlet, an internal plenum, and a series of vacuum lines formed in an adhesive element holding face. The vacuum tool is positioned over a reservoir of formed adhesive elements. Once the formed adhesive elements have been captured by the vacuum tool (10) the tool is used to place them into contact with the heated bonding part (14) directly or indirectly by intermediate placement onto a matrix (60) having a plurality of ejector pins (72) movably fitted therein. The ejector pins move the formed adhesive elements into position against the bonding part.
US09592970B2 Robotic gantry with end effector for product lifting
A robotic gantry system, end-effector for a robotic gantry system and method of transporting products using a robotic gantry system is provided. The end-effector includes a movable floor that can be positioned below picked products to prevent products from being dropped during transport. The movable floor also permits selecting individual rows of products from a given layer of products of a product stack. The end-effector may include a vacuum assembly for vacuum adhering to the products. The method permits selection of varying portions of a stack of products with the end-effector and protecting the selected portions of products using the movable floor.
US09592968B2 Conveying and alignment nozzle
A nozzle system that includes an improved air nozzle is provided. In one embodiment, the nozzle has an inlet and an outlet. An air source is connected with the nozzle through a conduit and generates an air flow using a high flow centrifugal blower. The nozzle is connected with and part of an air-driven orientation device.
US09592967B2 Preform conveying apparatus and method
An apparatus and a method for conveying preforms, to a blow molding machine. The apparatus includes a conveying device which conveys preforms away from a supply of preforms, a feeding device that receives preforms from the conveying device, and a sorting device that sorts the preforms and conveys them in a direction of travel. The conveying device ends above the sorting device. The inlet end of the feeding device has a holding zone which the preforms reach as they arrive from the conveying device, and the discharge end of the feeding device has a transfer zone via which the preforms reach the sorting device. The feeding device has an orienting zone with an orienting device designed so that the flow of preforms is oriented in the direction of the flow of the preforms in the sorting device (direction of travel), and the oriented preforms run through the transfer zone.
US09592959B2 Article transport facility with intermediate rack
An intermediate transfer device is located upwardly of an article delivering and receiving portion and downwardly of a ceiling transport vehicle. A transfer device grip is provided such that the intermediate transfer device is in vertical alignment with the ceiling transport vehicle and the article delivering and receiving portion and is capable of traveling, while guided and supported by a guiding support, to and among a transfer position for the delivering and receiving portion, a transfer position for the intermediate rack, a transfer-time retracted position, and a temporary-storage-time retracted. The guiding support is configured to form a space through which the grip portion and an article can pass in the vertical direction when the ceiling transport vehicle transfers the article.
US09592951B2 Container for food items
A combination of a container and a plurality of food items nested within the container may include base and a first cavity in the base. A first food item may be nested in the first cavity. The first food item may include a decorated section. The first food item may include a disposable wrapper having an exposed upper wrapper edge. The container may include a lid moveable between a closed position and an open position. A first retainer may be on the lid. When the lid is in the closed position the first retainer may overlie a first portion of the upper wrapper edge. When the container is inverted with the lid in the closed position relative axial movement between the first food item and the first cavity may be limited by contact between the first retainer and the upper wrapper edge.
US09592949B2 Device for dispensing a fluid product
A fluid dispenser device comprising: a fluid dispenser orifice (31); an air duct (32, 51, 52) for air under pressure, said air duct including an upstream end and a downstream end that opens out in the proximity of the orifice (31); an air expeller (4) that is suitable for being subjected to elastic squeezing and relaxation stages, the air expeller (4) being connected to the air duct (32, 51, 52) so that, during elastic squeezing stages, it delivers a flow of air through the air duct until it reaches the orifice (31); and a fluid channel (25, 33) that is connected to the air duct (32, 51, 52), the fluid in the channel (25, 33) being sucked up by the flow of air under pressure by the Venturi effect; the device being characterized in that the air expeller (4) has only a single opening (43) that is provided with a connection sleeve (5) that includes an incoming-air passage (53) that is provided with an air-inlet valve (56; 56b; 56c; 56d) that is suitable for allowing outside air to enter into the air expeller during elastic relaxation stages.
US09592946B2 Packaged solid object and method for manufacturing thereof
A packaged product which comprises a solid object and a packaging that seals and holds the solid object, wherein a replacement gas is contained in a space sealed by the packaging when the packaging is sealed and wherein the solid object has absorbed a part of or all of the replacement gas.
US09592943B2 Advertising package
Disclosed is an advertising package that consists of two trays that are hingedly attached along a longitudinal and transverse axis. One tray includes two compartments formed from substantially rectangular shapes to allow inclusion of items that are not distinctive in shape such as a coin, key or the like. The compartments are depressions which eliminates the need for upstanding side walls and the need for a circumscribing channel or coupling passageways. Printed material can be placed on the entirety of the first tray which provides a background to the compartments and allows viewing through the package sidewalls. The package is constructed and arranged to be sent as non-machinable flat through the United States Postal Service (USPS).
US09592942B2 Carton and carton blank
A carton has panels including a top panel (12/20), a base panel (16), a first side panel (14) and a second side panel (18) forming a tubular structure. One of the panels includes a handle structure (h) defined in it. The handle structure includes a first pair of folding structures (R, R) each having at least one first fold line (X, Y, Z) defining a first edge of a handle strap and a second pair of folding structures each having at least one second fold line defining a second edge of the handle strap. Each of the at least one first fold lines and the at least one second fold lines is defined, at least in part, in the one of the panels, wherein the carton includes a mandrel panel (22) disposed in face contacting relationship with the inner surface of the one (20) of the panels.
US09592941B2 Systems and methods for providing a thermoplastic product that includes packaging therefor
Systems and methods for providing a thermoplastic product that includes packaging therefore. Implementation of the present invention takes place in association with packaging of one or more ingredients of a thermoplastic product, wherein the packaging is used to contain the ingredients during storage and/or transportation, and wherein at least a portion of the packaging itself is an ingredient for inclusion into the thermoplastic product. In some implementations, the entire packaging is incorporated into the thermoplastic product for utilization thereof.
US09592940B2 Ingredient release spout
The present application provides an ingredient release spout with an ingredient therein for use on a container. The ingredient release spout may include a cap with the ingredient therein and a nozzle. The cap may include a diaphragm with a capsule insert extending therefrom. The nozzle may include a cutting device therein such that rotating the cap pulls the diaphragm and the capsule insert towards the cutting device.
US09592937B1 Tamper-evident container structure
Disclosed is a tamper-evident container for food storage that uses a round male to female post lock on a single corner. After the cover is locked to the tray base, it requires breaking the corner tray tab to open the container. This tab tear off provides positive evidence of container opening to indicate the container has been opened or tampered with.
US09592933B1 Gift container with insert for ejecting particulate material
An apparatus for containing a gift includes an outer container, such as a gift bag, having an opening for receiving the gift and an insert, such as a flexible packet, for containing a particulate material. The insert is adapted for attaching to the outer container to release the particulate material upon opening of the outer container to retrieve the gift. Related methods are disclosed.
US09592928B2 Reclosing mechanism for containers, particularly beverage containers
The reclosing mechanism for containers, particularly beverage containers, has the latch (3) fitted slidingly in the opening (5). Formed on the top side of the latch (3) there is an attachment (14) shorter than the opening (5) and narrower than the latch (3), where the attachment (14) is fitted with a pull tab (4) longer than the attachment (14) and fixed to the attachment (14) with a hinge (6) and a connector (7) which serves as the seal before the first opening. Formed on the opposite longitudinal sides of the attachment (14) there are catches (8) fitted slidingly on the guides (13) formed on the longer side walls of the opening (5). On the top surface of the element in which the opening (5) is made there are protrusions (10) formed on the side of the pull tab (4) front, on which the pull tab (4) rests and blocks the sliding of the latch (3) in the closed position.
US09592922B2 Satellite support structure comprising a damping connecting device
A satellite support structure to support at least one device of the satellite. The support structure includes structural elements with at least one of the structural elements being a damping connector linking at least two other structural elements of the support structure. The damping connector includes an elastomer element and at least one flat angle bracket having at least two wings to be linked by the respective connectors to the damped structural elements. The elastomer element is made from elastomer material with loss angle δ greater than ten degrees and is arranged such that the transmission of forces between one of the wings of the flat angle bracket and the connectors is achieved entirely via the elastomer element.
US09592921B2 Graphical representation of in-flight messages
A graphical in-flight message representation system comprises a sensor configured to measure a characteristic of a flight of an aircraft and a communication device configured to send and receive in-flight messages. An in-flight message is a message communicated during the flight of the aircraft. The system also comprises a display unit configured to display a graphical flight progress indicator and one or more message icons, each of the one or more message icons corresponding to a respective in-flight message. The graphical flight progress indicator is representative of the characteristic of the flight measured by the sensor. Each of the one or more message icons are displayed in location relative to the graphical flight progress indicator based on the measured characteristic of the flight when the respective in-flight message was communicated.
US09592919B2 Adapter for aircraft fluid transmission lines
One example of an aircraft fuel line assembly clamp member includes a c-shaped outer shell and a plurality of spokes. The c-shaped outer shell is sized to be positioned within an outer tube of an aircraft fuel line assembly. The plurality of spokes is arranged on an inner surface of the outer shell. The plurality of spokes protrudes from the inner surface towards a center of the outer shell to define a shape to receive an inner tube of the aircraft fuel line assembly. The plurality of spokes is also spaced apart on the inner surface.
US09592916B2 Aircraft air conditioning system and method for controlling an aircraft air conditioning system using a bypass valve
In a method for controlling an aircraft air conditioning system, a heating or cooling demand of an aircraft region to be air conditioned is determined. A volume flow of recirculation air discharged from the aircraft region to be air conditioned and a volume flow of compressed air into a mixing chamber of the aircraft air conditioning system is controlled such that the heating or cooling demand of the aircraft region to be air conditioned is met, while the volume flow of compressed air into the mixing chamber of the aircraft air conditioning system is minimized.
US09592915B2 System for securing an aircraft seat and aircraft seat comprising such a system
A device for securing an aircraft seat includes a base linked to the seat. The base includes a mechanism for fastening the base to a rail of an aircraft. The mechanism can be moved between locked and unlocked positions by an operating lever. The operating lever includes a visual indicator for indication of the locked and unlocked positions of the mechanism.
US09592913B2 Lightweight aircraft passenger seat assembly
A lightweight aircraft passenger seat assembly comprises at least one seat portion and at least one supporting portion for supporting the at least one seat portion relative to an aircraft structure. In order to provide an improved lightweight aircraft passenger seat assembly having a reduced weight, size and complexity as compared to conventional lightweight passenger seat designs, the invention provides a lightweight aircraft passenger seat assembly, comprising at least one seat portion with at least one seat shell for an aircraft passenger and at least one supporting portion for supporting the at least one seat portion relative to an aircraft structure, wherein the at least one seat shell and the at least one supporting portion are constructed as lightweight components.
US09592911B2 Context-based flight mode selection
Systems and methods for controlling an unmanned aerial vehicle within an environment are provided. In one aspect, a system comprises one or more sensors carried by the unmanned aerial vehicle and configured to provide sensor data and one or more processors. The one or more processors can be individually or collectively configured to: determine, based on the sensor data, an environment type for the environment; select a flight mode from a plurality of different flight modes based on the environment type, wherein each of the plurality of different flight mode is associated with a different set of operating rules for the unmanned aerial vehicle; and cause the unmanned aerial vehicle to operate within the environment while conforming to the set of operating rules of the selected flight mode.
US09592909B2 Antivibration suspension device for a mechanical element, and an aircraft
A suspension device (10) provided with at least one suspension means (20) comprising a flapper (21) performing pendulum motion, the flapper (21) being provided with a mass support (25) supporting at least one flapping mass (30). The mass support (25) is hinged to a carrier structure (2) for isolating and to a holder bar (15) for holding said mechanical assembly. The suspension device (10) includes at least one force generator (70), said suspension device (10) having at least one computer (50) connected to a measurement system (55) measuring the levels of vibration, and to said force generator (70) to regulate said amplitude and said phase actively by controlling the force generator (70) as a function of at least one measurement signal coming from said measurement system (55).
US09592903B2 Telescopic seat rail cover
A seat rail cover for a seat rail includes a first longitudinal section and a second longitudinal section. The first longitudinal section includes a first cover element and a first support element. The first support element extends in a longitudinal direction of the seat rail cover and protrudes from the first cover element transversely to the longitudinal direction. The second longitudinal section includes a second cover element and a second support element. The second support element extends in longitudinal direction and protrudes from the second cover element transversely to the longitudinal direction. The first longitudinal section is movable in longitudinal direction of the seat rail cover with respect to the second longitudinal direction from a non extended state to an extended state. Such a seat rail cover provides a variable length and may improve the dispersion of loads applied to the cover elements of the seat rail cover.
US09592897B2 Support of propeller unit for a vessel
The present invention relates to a rim driven propeller unit for a vessel, where a number of permanent magnets (4) are arranged round the propeller unit's rotatable rotor housing (1), comprising a number of propeller blades (3), and a number of permanent magnets round the propeller unit's external, stationary casing (2) housing the rotatable rotor housing, where the permanent magnets round parts of the rotatable rotor housing and the external, stationary casing's circumference are provided located above one another with like polarity, while other parts of the rotatable rotor housing and the external, stationary casing are provided located facing one another with opposite polarity, whereby the rotor housing and the stationary casing are repelled by and attracted to one another respectively, thereby being prevented from coming into contact with one another.
US09592896B1 Waterproof floatation case for outboard motor
A waterproof floatation case is provided for an outboard motor which is suitable for use during deployment for covert operations with an inflatable motor craft. The encased propulsion unit can be mounted without the need for removing the case and the two panels of the case butterflied between the motor and watercraft to permit full operation of the motor. A 2-way valve permits suction to be drawn down on the case evacuating excess air and corrosive fluids from the encased motor.
US09592891B2 Fluid transfer device, ship including the same, and fluid for use in transfer device
The present invention includes: first and second tanks and each configured to store a fluid containing fine powder; a communication pipe through which the first and second tanks and communicate with each other; and a transfer portion configured to transfer the fluid stored in a desired one of the first and second tanks to the other tank. Each of the tanks and includes a first chamber and a second chamber that are separated by a deformable dividing wall. Each of the first chambers stores an incompressible fluid, and each of the second chambers stores the fluid having higher specific gravity and viscosity than the incompressible fluid. The second chambers of the first and second tanks communicate with each other through the communication pipe. When the incompressible fluid is supplied to the desired first chamber, the transfer portion can discharge the incompressible fluid from the other first chamber.
US09592887B2 Watercraft with translationally shifting stern platform
A watercraft includes a hull provided with a stern compartment inside the hull, the compartment being closed at least on the bottom by a movable portion of a stern platform arranged at one end of the compartment itself which opens up astern of the watercraft, wherein the movable portion can be lowered relative to the hull into the water where the watercraft is floating. The movable portion of the stern platform shifts with a translational motion along the hull without moving away therefrom.
US09592883B2 Elliptical drive mechanism and a steering mechanism, applicable to velocipedes in general
“IMPROVEMENTS INTRODUCED IN AN ELLIPTICAL DRIVE MECHANISM AND A STEERING MECHANISM, APPLICABLE TO VELOCIPEDES IN GENERAL,” more specifically, it is about elliptical velocipedes (1) of the bicycle, tricycle, and scooter type, with said velocipedes having a tubular crossmember (2A) where the basic components are mounted, namely: fork (2b), handlebar mounting (2c), front wheel, rear wheel, center sprocket, and cranks, as well as an elliptical drive mechanism (M1) and a steering mechanism (M2). The structural frame (2) has a crossmember (2A), whose end is aligned with the imaginary center of the rear wheel, a tubular transverse shaft with tubular connections (3a) installed on its end portions, while a guide rod (3) that functions as a path for the sliding of the respective block (4) is attached to each of said connections. Each rod (3) is parallel to the crossmember (2A), while each sliding block (4) constitutes a platform whose lower bottom portion can be attached to a crank arm, which is, in turn, installed on the center sprocket of the velocipede (1), which drives a chain (5) that is responsible for transmitting motion to the ratchet mechanism. The lower surface of each plate (4) has at least two pairs of mountings (4a) with cross-sections in the shape of an inverted “L” on the side edges of the plate (4a), and they have pulleys (7) whose sections correspond to the sections of each guide rod (3). Because of the fact that the blocks (4) are mounted on the ends of the crank arms, sliding of said shoes on each guide rod (3) is in reverse, and, on account of the fact that the aforementioned rods (3) are linked to the transverse shaft, they produce an alternating upward and downward angular motion, thereby causing rotary motion of the cranks and, consequently, rotation of the center sprocket, the chain (5), and the ratchet mechanism, which, in this instance, is mounted on the front wheel, so as to constitute the elliptical drive mechanism (M1).
US09592880B2 Bicycle operating apparatus
A bicycle operating apparatus is provided with a base member, a ratchet, a pawl member and an operating member. The ratchet is rotatably disposed around a ratchet axis, and biased in a first direction about the ratchet axis. The operating member moves the pawl member from a first position to a second position. The pawl member has a pawl portion and first and second support portions. The pawl portion engages with the ratchet teeth while the pawl member is in the second position to regulate rotation of the ratchet in the first direction. The first support portion pivotally supports the pawl member around a first axis as the pawl member moves from the first position to the second position. The second support portion pivotally supports the pawl member around a second axis while the pawl member is in the second position.
US09592878B2 Scooter-type vehicle
A scooter-type vehicle including a front wheel, a steering mechanism, a vehicle frame, a saddle, a vehicle cover and a main switch unit. The vehicle frame includes a head pipe, a front frame and a rear frame. The front frame extends rearwards and downwards from a rear portion of the head pipe, and, in a front view, overlaps the front wheel when the steering mechanism is in a non-rotating state. The vehicle cover includes a flat-shaped pedal or footboard, which is further forwards than the saddle above the rear frame, and a front cover extending upwards from a front end of the flat-shaped pedal or footboard. In a side view, at least a part of the main switch unit is further forwards than an imaginary line connecting a rear end of an upper edge of the head pipe and a rear end of a lower edge of the front frame.
US09592872B2 Motorcycle
A motorcycle is provided which can enhance a cooling effect of a radiator while suppressing traveling resistance generated by a front fender. In a motorcycle which includes a front fender which is arranged between the left and right fork assemblies which constitute a front fork, and covers the front wheel from above, radiators are provided as a pair of left and right radiators, respective inner edges of the left and right radiators and the front fender overlap with each other as viewed from a front side, and a pair of left and right openings which extends in a vertical direction is formed in a rear portion of the front fender.
US09592870B2 Bicycle with an intelligent system
An intelligent system for a bicycle is provided with a control assembly including a seat bag control device, a sensor device, a digital camera, a lighting device, a warning device, and a power supply for supplying DC power to above components; and a display assembly including an LCD screen, a processing module, a communications module, and a power module for electrically interconnecting the LCD screen, the processing module, and the communications module. The seat bag control device includes a microprocessor, a memory, and a wireless communications module. The sensor device includes an optical sensor, a thermometer, an acceleration sensor, a barometer, a gyroscope, an electronic compass, a radar, and a GPS. The digital camera includes a rear camera. The lighting device includes an auxiliary light, a rear light, a directional light, and a decoration light. The warning device includes a loudspeaker and a vibration module.
US09592869B2 Seat peripheral structure for saddle type vehicle
A rear seat for a saddle type vehicle that is readily adjustable without changing the position of a main seat to improve the riding comfort of the rear seat. A saddle type vehicle includes a head pipe, a main frame provided behind the head pipe and a seat rail extending to the rear of the main frame. A main seat is provided with a rear seat provided behind the main seat and formed as a separate member from the main seat. The rear seat is attached to a rear seat holding portion provided at a rear portion of the seat rail through a base plate for holding the rear seat thereon. The rear seat can be moved forwardly and rearwardly by making it possible for the base plate to be fixed at a plurality of positions in the forward and rearward direction with respect to the rear seat holding portion.
US09592866B2 Track assembly having a wear monitoring system
A track assembly may have a chain assembly including a plurality of track links, a traction assembly including track shoes secured to the plurality of track links, a drive sprocket, an idler assembly including an idler and a mount, and a roller assembly including a plurality of rollers and a roller frame. A wear monitoring system may have a wear sensor configured to generate a signal indicative of a current position of a first component of the track assembly, and a controller in communication with the at least one wear sensor, the controller being configured to determine an amount of wear experienced by the track assembly based on the signal. The first component may be configured such that wear of at least a second component causes the first component to move to the current position from a previous position.
US09592861B2 Axle mounted spare tire assembly apparatus and method of use
An axle mounted spare tire assembly is disclosed for use in replacing a damaged vehicle tire or tire support structure to permit a vehicle to then travel to a vehicle repair shop. The apparatus is comprised of a saddle which surrounds and bolts onto a vehicle's axle. A support tire is mounted below the saddle on a self-locking axle and will rotate as the vehicle is driven. The saddle is provided with a plurality of bolts to facilitate attachment to round, U-shaped, and square vehicle axles. The saddle is also equipped with a detachable handle to allow for ease of attachment and transfer of the assembly to and from the damage site.
US09592860B1 Pick up truck elongator
A replacement tailgate for the purpose of elongating the pickup truck may be installed on a truck bed wherein the replacement tailgate can be unfolded in order to elongate a length of the truck bed. The replacement tailgate may have front and rear shells that are used to support objects placed in the truck bed as well as act as the new tailgate when the truck bed length is elongated. Various panels may be unfolded in order to trap objects within the truck bed when the replacement tailgate is unfolded in order to elongate the truck bed length.
US09592859B1 Trailer with lower level load space and upper level living quarters
A multipurpose trailer including a trailer structure, a wheel assembly and a hitch assembly is disclosed, wherein the lower level includes a first cargo space such as for containing and transporting livestock. An upper level is located above the lower level, and includes a second cargo space adapted and constructed to provide, for instance, living space for humans. A roof assembly is connected to the upper level, whereby the roof assembly is convertible between a first, closed position in which the roof assembly is folded over the second cargo space of the upper level, and a second, open position in which the roof assembly is open to the ambient environment.
US09592857B2 Closing plug for an opening in a body structure of an automobile
A closing plug for an opening in a body structure of an automobile, wherein the closing plug closes the opening against a passage of fluid and/or gas up to a limit pressure which acts on the closing plug, and allows a passage of fluid and/or gas above the limit pressure, characterized in that the closing plug comprises a base body consisting of a first plastic material, which has a holding section with holding means for holding the closing plug in the opening and a plate-shaped head section provided on one end of the holding section with at least one opening and that the closing plug comprises a sealing body of a second plastic material molded onto the base body in a plastic injection molding process.
US09592854B2 Vehicle front portion structure
There is provided a vehicle front portion structure including (1) a suspension member having (i) a front cross member and a rear cross member, and (ii) a side rail that couples vehicle width direction outside end portions of the front cross member and the rear cross member, (2) a lower arm whose vehicle width direction outside end portion is coupled to a front wheel and whose vehicle width direction inside end portion is coupled at least to a front side coupling portion and a rear side coupling portion of the suspension member, and (3) a weak portion that is formed in the front cross member on the vehicle width direction inside of a coupling point at which the lower arm and the front side coupling portion are coupled to each other and that is to be broken by a load input from the vehicle body front side.
US09592853B2 Corrugation designs
Provided is a load-carrying or non-load carrying structural component for a vehicle having improved impact resistance, such as a gas tank protection shield, an underbody shield, a structural panel, an interior floor, a floor pan, a roof, an exterior surface, a storage area, a glove box, a console box, a trunk, a trunk floor, a truck bed, and combinations thereof. The component has a support structure with ridges, each spaced apart from one another at predetermined intervals, to form a corrugated surface capable of load-carrying. The ridges are longitudinally extending, raised ridges and define top and side walls. A plurality of strategically thickened areas is on at least one of the top wall and side walls.
US09592849B2 Electric power steering system with motor controller
An electric power steering system for a vehicle works to determine an assist command based on steering torque to produce assist torque through an electric motor for assisting in turning a steering wheel of the vehicle, also determines a tracking command for producing automatic steering torque which brings a value of a given physical quantity associated with steering of the vehicle into agreement a target value, and calculates a vibration correction command for use in producing vibration correction torque which suppresses vibration of the steering torque which arises from output of the torque from the electric motor based on a transfer characteristic of transmission of the output of torque from the electric motor as a part of the steering torque through the steering mechanism. A motor driver works to actuate the electric motor based on the sum of the assist command, the tracking command, and the vibration correction command.
US09592844B2 Locomotive driver's cab
A locomotive driver's cab allows a locomotive driver a comparatively long time for observing a route by providing the locomotive driver's cab with a front vision display for displaying rail-vehicle-relevant information in the field of vision of the locomotive driver.
US09592843B2 System and method for identifying point detection calibration prior to point detector lock-out and switch machine failure
A detection and indication system for use in a railway switch machine which utilizes one or more roller members which physically interact with a point detector bar coupled to one or more switch points to provide an indication of a point failure upon movement of the point detector bar a predetermined distance from an initial position. The system includes a mounting structure structured to be coupled to a housing of the switch machine and a first sensing device coupled to the mounting structure. The first sensing device is positioned and structured to detect movement of the point detector bar a second predetermined distance from the initial position, wherein the second predetermined distance is less than the first predetermined distance.
US09592842B1 Railroad locomotive control system having switch position indication and method of use
A locomotive control system and method of use operable to provide operational control of a locomotive ensuing the detection that the locomotive will enter a railroad switch having the point blades incorrectly positioned. The locomotive control system further includes a point alignment detection sensor being operably coupled to a railroad switch and the point blades thereof. A plurality of track transceivers are mounted adjacent to the railroad switch and extend outward from the railroad switch along the railroad track. At least one engine transceiver is provided and is operably coupled to a locomotive. A controller is included and functions to provide logic and control of the locomotive control system. The method provides monitoring of the point blades of a railroad switch and detection of the movement of an approaching locomotive having entered the detection zone and is operable to prevent movement through the railroad switch if damage will occur thereto.
US09592839B2 Railcar
A railcar includes: a pair of side sills extending in a railcar longitudinal direction; end beams respectively located at railcar-longitudinal-direction end portions of the side sills to extend in a railcar width direction; bolster beams located at a railcar-longitudinal-direction inner side of the end beams to extend in the railcar width direction and respectively placed on bogies; center sills each located between the end beam and the bolster beam to extend in a railcar longitudinal direction; a plurality of cross beams located at a railcar-longitudinal-direction inner side of the bolster beams to extend in the railcar width direction; and a corrugated plate fixed to upper surfaces of the cross beams to be displaceable relative to the bolster beams in the railcar longitudinal direction.
US09592837B2 Valve for outlet gate assembly for hopper cars
An outlet gate assembly includes a body and an elongated discharge opening. An elongated discharge conduit is generally adjacent the discharge opening and is configured to pass material through either of the first discharge end and the second discharge end. A valve assembly controls the flow of material from the discharge opening into the discharge conduit and includes a direct motion component and a lost motion component and a lost motion coupling between the direct motion component and the lost motion component. Each of the direct motion component and the lost motion component is rotatable to move between an open position and a closed position and the valve assembly is operable from either the first end or the second end of the body.
US09592834B2 Vehicle environment recognizing apparatus
A vehicle environment recognizing apparatus comprises an image capturing device, a road shape calculating section and a straight road determining section. The image capturing device is configured to capture an image of a road on which a vehicle is traveling. The road shape calculating section is configured to calculate approximation lines that approximate a shape of the road in at two least regions that are located at different distances in front of the vehicle based on image data captured by the image capturing device. The straight road determining section is configured to determine whether the road on which the vehicle is traveling is straight based on a degree to which the approximation lines of the regions calculated by the road shape calculating section match one another.
US09592828B2 Long term driving danger prediction system
Systems and methods are disclosed to assist a driver with a dangerous condition by creating a graph representation where traffic participants and static elements are the vertices and the edges are relations between pairs of vertices; adding attributes to the vertices and edges of the graph based on information obtained on the driving vehicle, the traffic participants and additional information; creating a codebook of dangerous driving situations, each represented as graphs; performing subgraph matching between the graphs in the codebook and the graph representing a current driving situation to select a set of matching graphs from the codebook; determining a distance metric between each selected codebook graphs and the matching subgraph of the current driving situation; from codebook graphs with a low distance, determining potential dangers; and generating an alert if one or more of the codebook dangers are imminent.
US09592813B2 Actuator assembly for a parking brake system
Disclosed is an assembly that includes a spindle; a brake cable in communication with the spindle; and a spring in communication with the spindle. Movement of the spindle in a first direction causes the brake cable to move so that a clamping force is created. Movement of the spindle in a second direction causes the brake cable to move in a second direction so that the clamping force is released. Movement of the spindle in both the first direction and the second direction causes the spring to compress so that a controller can determine when the clamping force is created and released.
US09592812B2 Method for operating an electromechanical vehicle brake system
A method for operating an electromechanical vehicle brake system is provided. The method includes determining that an activation condition has been met, selecting a pre-charge pressure based at least in part on the activation condition, building up at least an initial portion of the pre-charge pressure in the brake system, and applying at least the initial portion of the pre-charge pressure to at least one wheel brake.
US09592808B2 Pump housing for a motor vehicle hydraulic assembly with a connection for a wheel pressure sensor or a master brake cylinder pressure sensor
A pump housing has at least two inlet valve openings located in a first row, at least two outlet valve openings located in a subsequent second row, and at least one high-pressure switching valve opening and at least one changeover valve opening located in a further subsequent fourth row. At least one connection for a wheel pressure sensor is positioned in a third row between the second and fourth rows. At least one connection for a master cylinder pressure sensor is positioned in a fifth row following the fourth row.
US09592807B2 Brake chamber, boot member, and bush member
A brake chamber includes a rod member that makes reciprocating motion within a cylinder through a pressure of compressed air or an urging force of a spring, thereby causing a pushrod for activating a brake device of a vehicle to proceed into the brake device. The brake chamber further includes a diaphragm that deforms in response to supply of the compressed air to push the rod member, and a housing that forms an accommodation space for the diaphragm. The housing is connected to the cylinder with a first end of the cylinder being inserted in the housing. The brake chamber further includes a boot member connected to the cylinder and the rod member. The boot member includes a sealing portion to prevent entry of foreign matter into a connection portion between the housing and the cylinder by contacting an inner circumferential surface of the housing.
US09592805B2 Method and system for control of auxiliary brakes
A method and a system to control an auxiliary brake system in a vehicle 100 having a service brake system 150 and an auxiliary brake system 160. Also a system for prevention of wheel lock when braking, which may deactivate a braking action provided by the auxiliary brake system 160 and may actively control a braking action provided by the service brake system 150. The system determines whether the vehicle 100 is in a driving mode for which it is acceptable in terms of safety and/or drivability to block the deactivation of the braking action for the auxiliary brake system 160. If a first manual control 170, which is set up solely for activating braking action for the auxiliary brake system 160, is activated, this means it is acceptable, from a safety and/or drivability point of view, for the driving mode in question, to block the deactivation. Also arranging block deactivation for the auxiliary brake system 160 if it is acceptable in terms of safety and drivability to block it.
US09592797B2 Wheel well ice buildup removal assembly
A wheel well ice buildup removal assembly includes a cylinder having a first end, a second end and a perimeter wall. The first and second ends each have an opening extending therethrough. A rod extends through the first end and has an outer end positioned outside of the cylinder and an inner end positioned in the cylinder. A head is attached to the inner end and has a distal end that is pointed extending outwardly of the second end. The distal end is positionable in a retracted condition positioned within the cylinder and a deployed condition positioned outside of the cylinder. A spring is mounted within the cylinder and biases the head away from the first end and outwardly of the second end. The rod is pulled outwardly away from the first end and released to cause the head to forcibly extend from the cylinder.
US09592795B1 Theft deterrence, prevention, and recovery system and method
A theft deterrence, prevention, and recovery system for use in monitoring a theft status of a vehicle includes a cabin module positioned in the interior cabin of a vehicle, the cabin module having a memory, a processor, and an input device such as a touch screen display. The cabin module may include a camera configured to record video in the cabin vehicle and a cabin microphone configured to record audio in the vehicle cabin. The input device may be activated by a driver to indicate the immediate occurrence of an emergency event—such as a carjacking. If the input device is activated, the camera, microphone, and a global position (GPS) device may be activated. Collected data may be transmitted, such as by cellular or electromagnetic infrared signals. A vehicle smoke sensor may also be included.
US09592790B2 Dual stage air bag inflator
An apparatus (12) provides inflation fluid for inflating an inflatable vehicle occupant protection device (14). The apparatus (12) includes a primary housing (20), a primary inflation fluid source (100), a secondary housing (70), and a secondary inflation fluid source (200). The primary housing (20) is constructed from sheet metal by stamping. The primary inflation fluid source (100) is located in the primary housing (20). The primary inflation fluid source (100) is actuatable to effect a primary flow of inflation fluid out of the primary housing (20) to inflate the inflatable device (14). The secondary housing (70) is constructed from sheet metal by stamping. The secondary housing (70) is disposed within the primary housing (20). The secondary inflation fluid source (200) is located in the secondary housing. The secondary inflation fluid source (200) is actuatable to affect a secondary flow of inflation fluid to supplement the primary flow of inflation fluid. The secondary housing (70) has a first portion (77) that moves at least partially out of engagement with a second portion (74) of the secondary housing (70) when the secondary inflation fluid source is actuated.
US09592787B2 Airbag for knee airbag apparatus
An airbag for a knee airbag apparatus which is rapidly deployed upward between the knees of a passenger and instrument panel includes a front panel; a rear panel coupled to the front panel to form an inflation chamber; and a hinge portion having a thin inflation thickness at a position corresponding to a housing connecting portion, at which the instrument panel is coupled to the housing, when the airbag is inflated.
US09592786B2 Clip, curtain airbag mounting structure and pillar garnish mounting structure
A clip includes a clip main body. The clip main body has a pair of locking pawls which are deformable in a direction in which they approach each other. The pair of the locking pawls have internal side faces opposed to each other. A projection/recess is provided on at least part of the internal side face of the pair of the locking pawls. A projection portion of the projection/recess of the locking pawl on one side is opposed to a recess portion of the projection/recess of the locking pawl on the other side.
US09592782B2 Vehicle
A utility vehicle includes front and rear ground-engaging members configured to contact a ground surface, a drivetrain assembly operably coupled to the ground-engaging members, and a frame supported by the ground-engaging members and extending along a longitudinal axis of the utility vehicle. The utility vehicle also includes a rear cargo bed assembly supported by the frame and extending over a portion of the rear ground-engaging member. The rear cargo bed assembly has a rear platform with at least a first seating position. Additionally, the utility vehicle includes a rear cab frame assembly with an upright position and a collapsed position. The vehicle has a first height from the ground surface when the rear cab frame is in the upright position and a second height from the ground surface less than the first height when the rear cab frame is in the collapsed position. The second height is 72-84 inches.
US09592777B1 Positive locating grommet with NVH flap
A grommet configured to pass through a vehicle wall and an acoustic mat is provided. The grommet includes first and second sealing segments, a mounting segment, and a pass-through segment. A flange configured to abut the vehicle wall extends from the first sealing segment. The pass-through segment has a NVH flap that is configured to abut the acoustic mat. The grommet has a grommet installation coupling that includes a mounting hole in the flange for receiving a mounting stud that extends from the vehicle wall and an engagement member that engages the mounting stud. The engagement member applies an installation force to the flange, which moves the grommet longitudinally from a first installation position to a second installation position and pushes the NVH flap against the acoustic mat so that the NVH flap is deflected back toward the flange as the grommet moves to the second installation position.
US09592775B2 Wiring harness protector fixing structure
It is aimed to provide a wiring harness protector fixing structure having a novel structure and capable of firmly positioning and fixing a protector to an end part of a wiring harness with excellent durability while improving waterproofness even if a mounting member such as a vehicle body panel is not present around. Engaging projections are formed on a flange portion of a metal bracket, whereas a wiring harness protector includes a first divided body and a second divided body to be assembled and integrated. By assembling the first and second divided bodies, the engaging projections of the metal bracket are engaged with engaging holes provided on flange wall portions of the first and second divided bodies, and contact surfaces and provided on at least parts of the flange wall portions come into contact with the flange portion of the metal bracket.
US09592774B2 Wire harness
The wire harness according to the present invention comprises electric wires each including a conductor. The electric wire is configured of a low-current electric wire used for a power source circuit, a high-current/ground electric wire used for a high-current power source circuit or a ground circuit and allowing a larger current than that of the low-current electric wire to flow, and a signal electric wire used for a signal circuit. The low-current electric wire and the high-current/ground electric wire are formed of an aluminum electric wire in which the conductor is made of aluminum or an aluminum alloy. The signal electric wire is formed of a copper electric wire in which the conductor is made of copper or a copper alloy.
US09592770B2 Loudspeaker system for a motor vehicle
A loudspeaker system for a motor vehicle has a loudspeaker, which is arranged adjacent to at least one wall of the motor vehicle. At least one pipeline originates from the loudspeaker and runs through the wall. A shut-off device for the at least approximately sound-tight closure of the pipeline is arranged in the pipeline.
US09592767B2 Multipurpose cargo net and hook system
A cargo management system for a vehicle includes a first pair, a second pair, and a third pair of anchors. The first and second pairs of anchors are positioned adjacent each other and the third pair of anchors is positioned remote from the first pair. The system further includes a flexible substrate having a first pair of attachment features coupleable with the first pair of anchors and a second pair of attachment features selectively coupleable with the second pair or third pair of anchors.
US09592762B2 Vehicle driving assistance apparatus
A vehicle driving assistance apparatus includes a coherent light source, a road surface projection optical system, a road surface wet information retention section, and a control circuit. The road surface projection optical system scans a light source beam emitted from the coherent light source to output a projection beam, and thereby project the light pattern on the road surface around the own vehicle, the light source beam being light. The control circuit is configured to stop the output of the projection beam during a period in which the road surface wet information retention section retains information indicating that the road surface around the own vehicle is wet. The projection beam enters the road surface around the own vehicle at a shallow angle, and projects the light pattern toward a road surface near a boundary of a traveling lane where the own vehicle is traveling.
US09592755B2 Vehicle seat
The time until a headrest contacts the head of an occupant in the event of a rear collision is shortened with a simple configuration. In a seat device, a stay (46) (including grommets (22)) is set with bending rigidity towards the vehicle front lower than the bending rigidity towards the vehicle rear. Accordingly, when the headrest oscillates in the event of a vehicle rear collision, the headrest is initially displaced towards the vehicle rear, however the headrest changes direction in a short time and begins to be displaced towards the vehicle front. Moreover, there is a large displacement of the headrest towards the vehicle front since the stay (46) (including the grommets (22)) has a lower bending rigidity towards the vehicle front than the bending rigidity towards the vehicle rear. The time until the headrest contacts the head (H) of the occupant can accordingly be shortened. The headrest can be promptly displaced towards the side of the head (H) of the occupant due to setting the bending rigidity of the stay (46) including the grommets (22), thereby enabling the time until the headrest contacts the head of the occupant to be shortened with a simple configuration.
US09592752B2 Energy-dissipation system
A child restraint includes a juvenile vehicle seat and an energy-absorption apparatus coupled to the juvenile vehicle seat. The energy-absorption apparatus is configured to absorb external energy associated with an external impact force applied to the energy-absorption apparatus.
US09592751B2 Child safety seat for use in a vehicle
A child safety seat comprising a base placeable on and securable to a vehicle seat and a seat element releasably engageable with the base. The base has an inclination adjustor which is selectively adjustable in at least two different positions relative to a base body in order to adjust the inclination of the base with respect to the vehicle seat. The adjustor includes a locking mechanism for locking the adjustor in a selected adjustment position and for releasing the adjustor in order to allow for selection of another adjustment position. An actuator operates the locking mechanism to lock or release the adjustor. The actuator is positioned on the base so that the actuator is covered by the lower surface of the seat element when the latter is fixed to the base. The actuator therefore cannot be accessed without unlocking and separating the seat element from the base.
US09592750B2 Child seat lock device
A child seat lock device has an anchor that is secured to a vehicle body frame and retains a catch of a child seat in a removable manner. A seat cushion is attached to the vehicle body frame independently of the anchor. The seat cushion has a cushion pad that is provided with a groove that houses the catch retained by the anchor and extends in a front-rear direction of the seat. A skin is provided for covering the cushion pad and has, at a location in front of the groove, an insertion slit into which the catch is inserted. A guide is provided for guiding the inserted catch from the insertion slit toward the anchor at the position of the groove. The guide is harder than the cushion pad.
US09592747B2 Method and system for controlling the powertrain of a vehicle
The disclosure relates to a method for controlling the powertrain of a vehicle, which powertrain comprises a first electric drive device for driving of a first drive shaft and a second electric drive device for driving of a second drive shaft of the vehicle, comprising the step of via power electronics providing electricity supply of a first electric motor of the first electric drive device and a second electric motor of the second electric drive device, comprising the step of providing said electricity supply from a common power electronics which supplies said first and second electric motors with electricity, which motors hereby are connected in parallel. The disclosure also relates to a system for controlling the powertrain of a vehicle. The present invention also relates to a motor vehicle. The present invention also relates to a computer program and a computer program product.
US09592746B2 Power net system of fuel cell hybrid vehicle and charge/discharge control method
A power net system of a fuel cell hybrid vehicle includes a fuel cell and an electric vehicle battery (EV battery) connected with each other through a main bus terminal in parallel, and an insulated gate bipolar mode transistor (IGBT) connected to the EV battery and the main bus terminal. The power net system further includes an inverter connected to the main bus terminal and a driving motor connected to the inverter.
US09592744B2 Battery and unmanned aerial vehicle with the battery
The disclosure provides a battery which can include a power supply and power supply circuit, the power supply circuit connected to the power supply. The power supply can discharge through the power supply circuit. An electronic switch can control the power-on or off of the power supply, thereby avoiding the generation of sparks during the power on process and allowing for the normal use of the battery and the safety of the aircraft. The disclosure also provides an aircraft having the battery.
US09592741B2 Charging control apparatus, charging control method, and computer program implementing such
A charging control apparatus (310) controls wireless charging between one charging apparatus (10) and a vehicle (20) which communicates with the one charging apparatus via a communication relay apparatus (30). The charging control apparatus is provided with: an outputting device (320, 330) for transmitting a first signal which is a signal for designating a signal outputted from the one charging apparatuses, to of the one charging apparatuses; a detecting device (320, 330) for detecting a third signal which is transmitted by wireless communication from the vehicle and which is a signal corresponding to a second signal which is a signal outputted from the one charging apparatus due to the transmitted first signal; and a distinguishing device (310) for correlating the one charging apparatus with the vehicle on the basis of the transmitted first signal and the detected third signal.
US09592739B2 Drive control equipment for a vehicle
Drive control equipment for a vehicle comprises: a plurality of power conversion devices respectively connected with a plurality of motors that convert DC power supplied from a DC power source to AC power and output this to said motors; a control device that controls the power conversion devices; a frame that accommodates said power conversion devices and the control device and having a ceiling wall facing below the vehicle floor; and a power unit having a cooler in which are installed a plurality of semiconductor elements constituting the power conversion devices; a first control board provided with a first connector connected with said semiconductor elements, arranged facing the cooler; and a second control board arranged in a direction orthogonal to said first control board and connected with a second connector connected with the first connector of said first control board.
US09592737B2 Redundant drive system
The invention relates to a drive system (1). The drive system (1) has at least two inverters (3, 31, 32, 33) and at least two motors (2). Each of the motors (2), each of which has a stator and a rotor, has at least one first coil system (21) and a second coil system (22) in the stator. Each first coil system (21) is connected to a first inverter (31) in an electrically conductive manner, and each second coil system (22) is connected to a second inverter (32) in an electrically conductive manner. The invention further relates to a method for the redundant operation of a drive system (1), wherein at least one motor exchanges electric energy with the second inverter (32) and/or one or more additional inverters (33) if the first inverter (31) fails.
US09592736B2 Controlling a locking device of an electric charging port
A method for controlling a locking device of an electric charging port of a vehicle. The vehicle has a keyless entry system, which makes it possible for the vehicle to be unlocked without the active operation of a vehicle key. Presence information of the vehicle key in the vicinity of the vehicle is detected and further a state of charge is detected that indicates whether a charging process is currently taking place via the charging port. The locking device is activated depending on the presence information and the state of charge.
US09592734B2 Cluster information output apparatus for vehicle and control method thereof
A cluster information output apparatus for a vehicle may include: a plurality of peripheral control devices having a function of displaying cluster information; a storage unit configured to store the cluster information and priorities for the plurality of peripheral control devices; and a control unit configured to determine operation states for the plurality of peripheral control devices when an error occurs in an operation state sensed from a cluster, and output the cluster information.
US09592732B2 Vehicle powertrain with dual-independent transmissions
A dual-independent powertrain for a vehicle includes a transmission enclosure that houses a first transmission and a second transmission that are mechanically decoupled from each other. The enclosure includes a central frame, a first enclosure cover that interfaces with the central frame to collectively define a first transmission region on a first side of the central frame, and a second enclosure cover that interfaces with the central frame to collectively define a second transmission region on a second side of the central frame. The first transmission is housed within the first transmission region, and the second transmission is house within the second transmission region. Each transmission includes a motor-interfacing shaft that interfaces with a respective electric motor, a drive-interfacing shaft that interfaces with a respective drive wheel of a vehicle, and a multi-stage gear train mechanically coupling the motor-interfacing shaft and the drive-interfacing shaft.
US09592731B2 CNG fuel system for a vehicle
A fuel management module for use with a CNG fuel system for a vehicle includes a housing configured to be connected to the vehicle and a number of connections, receptacles, and controls associated with the module. A defueling receptacle may be positioned on the front panel of the housing, for defueling a fuel tank of the vehicle. A defueling control valve may be positioned on the front panel of the housing for controlling operation of the defueling receptacle, allowing for selective defueling. One or more high pressure connections may be accessible on the housing and configured for connection to one or more separate fuel tanks in a plug and play configuration. A plurality of filling connections may be accessible on the housing for filling the fuel tank(s). A low pressure fuel output connection may be positioned on the back panel of the housing to provide fuel output from the high pressure connections to the engine.
US09592729B2 Fuel tank
The fuel tank according to the present invention is a fuel tank including a fuel supply device for pressure-feeding fuel to an engine of a vehicle; a fuel vapor treating device configured to enable adsorption of fuel vapor; a fuel tank body which stores the fuel; and a cover material which blocks an opening portion formed in the fuel tank body, wherein an inlet portion to which an inlet pipe for guiding the fuel from a fueling port to the fuel tank body is connected is fixed to the cover material in a state of penetrating the cover material, and a pipe and a wire of the fuel supply device and pipes of the fuel vapor treating device are further fixed to the cover material in a state of penetrating the cover material.
US09592728B1 Bushing mount and holding structure for in-vehicle component
A bushing mount for an in-vehicle component disposed on a vehicle body includes a support and an insertion portion. The support includes a support body defining a pin hole therein, and the insertion portion is connected to the support. The support body includes a contact surface that abuts the vehicle body when the insertion portion is inserted into an attachment hole formed in the vehicle body. The support supports, when a pin of the in-vehicle component is inserted into the pin hole, the in-vehicle component while being interposed between the vehicle body and the in-vehicle component. The support includes a removal portion that allows the pin to be removed out of the pin hole in a direction angled from a center axis of the pin hole.
US09592723B2 Vehicle sunroof device
A vehicle sunroof device in which a movable panel is supported by a panel support member and the movable panel is capable of being moved in a tilted manner, the movable panel is prevented from being detached due to an upward load without increasing the thickness and the weight of the cored bar of the panel support member in a low-cost structure. A portion of the cored bar of the panel support member, which is located under cam grooves is bent to form first and second protrusions which protrude laterally in the thickness direction of the cored bar. The first protrusion is formed by notching multiple parts of the cored bar and bending the notched parts.
US09592722B2 Retractable headliner corner
A headliner corner retractor for a convertible top. The corner retractor moves a front corner of the headliner between a covering position concealing a front portion of the side linkage and a contracted position in which clearance is provided for the side linkages to extend and retract the convertible top. The corner retractor is moved by a mechanical actuator including a cable and a hollow tubular housing.
US09592718B2 Integrated cooling system control method
A control method for an integrated cooling system may include determining whether an air conditioner is operated or not, and controlling operations of a water pump for electric devices and a cooling fan by the controller according to a predetermined first map when the air conditioner is not operated, detecting an air conditioner refrigerant pressure when the air conditioner is operated, determining whether the air conditioner refrigerant pressure is within a predetermined range or not, and controlling operations of the water pump for electric devices and the cooling fan according to a predetermined second map when the air conditioner refrigerant pressure is not within the predetermined range, and determining of cooling requirement of the condensers and controlling operations of the water pump for electric devices and the cooling fan according to the cooling requirement of the condensers when the air conditioner refrigerant pressure is within the predetermined range.
US09592713B2 Air intake system for a vehicle
A utility vehicle is disclosed. The utility vehicle may include storage areas under the dash. The utility vehicle may include suspension systems for utility vehicles having shocks with both a fluidic stiffness adjustment and a mechanical stiffness adjustment. The utility vehicle may include an electrical power steering.
US09592712B2 Suspension apparatus
A suspension apparatus includes: a cylinder connected to one of a sprung member and an unsprung member, an interior space of the cylinder being partitioned into a piston upper chamber and a piston lower chamber; a piston connected to the other of the sprung member and the unsprung member; an expansion side friction member configured to damp a movement of the piston, a force of the expansion side friction member for damping the movement of a piston being increased by exerting a pressure of the piston upper chamber on the expansion side friction member; and a contraction side friction member configured to damp the movement of the piston, a force of the contraction side friction member for damping the movement of the piston being increased by exerting a pressure of the piston lower chamber on the contraction side friction member.
US09592707B2 Tire
A tire is provided with multiple projection parts in a groove bottom of a groove portion. The projection parts extend from one side wall to the other side wall opposed to the one side wall, the side walls forming the groove portion. The projection parts are arranged at predetermined intervals in the groove portion. Lateral groove portions that extend from the groove portion to a buttress section, and have openings in the buttress section are formed. Air supply mechanisms that supply air to the lateral groove portions are formed.
US09592706B2 Pneumatic tire
A shoulder land portion is constructed by block rows. Shoulder lateral grooves sectionalize the block rows. The shoulder lateral grooves extend along the tire width direction in such a manner as to cut across ground contact ends. A plurality of projections is provided on a wall surface of the shoulder lateral groove. The projections protrude out of the wall surface of the shoulder lateral groove without reaching a center of a groove width of the shoulder lateral groove and are lined up in a length direction of the shoulder lateral groove in an outside area in the tire width direction from the ground contact end. The projection is formed into a triangular shape or a trapezoidal shape in its plan view and is formed into a triangular shape or a trapezoidal shape in its front elevational view.
US09592702B2 Friction body, writing instrument and writing instrument set
There is provided a friction body which is adapted to rub a thermochromic image or handwriting formed on a paper surface by use of thermochromic ink to thermally discolor the thermochromic image or handwriting by frictional heat resultant from rubbing, a thermal conductivity of a friction portion of the friction body is set to be within 0.05 W/(m·K) to 50 W/(m·K).
US09592694B2 Pressure sensitive coating for image forming
A microencapsulated pigment including a leuco dye system is incorporated as one or more layers in a roll of adhesive tape. The tape is applied and may be rubbed by hand or another object to induce a color change. The change may serve as an indicator that the tape is well adhered for masking purposes in a painting operation, or to present a design where only selected portions of the tape are rubbed to induce the color change. The microencapsulated pigment may be constructed so that the color change is irreversible or reversible.
US09592693B2 Process for decorating the surface of a substrate with a three-dimensional and tactile effect
The process for decorating the surface of a substrate comprises the stages of printing a three-dimensional decorative pattern on one surface of a polymer film using resin, placing the decorated surface of the film and at least one surface of the substrate in contact and providing thermal energy thereto, and detaching the film from the substrate onto the surface of which the three-dimensional decorative pattern has been transferred.
US09592692B2 Tape cassette
A tape cassette that includes a housing, a wound tape, an arm portion, and a first surface. The housing has a top surface, a bottom surface, and a front surface. The front surface extends from the bottom surface toward the top surface in a first direction. The arm portion is defined by a section of the front surface and a first wall. An opening extends through the housing in the first direction. The opening is defined by the first wall, a second wall, and a connection portion. The first surface is provided in the connection portion. The first surface is disposed between the top surface and the bottom surface in the first direction. The housing has a first indentation extending from the bottom surface to the first surface.
US09592690B2 Print head, upgrade kit for a conventional inkjet printer, printer and method for printing optical structures
The invention relates to a print head for printing optical structures on a substrate comprising an ejection device for ejecting at least one droplet of a printing ink towards the substrate in order to build up the optical structure, wherein the print head comprises a measurement means for contactless measuring at least one physical parameter of the at least one deposited droplet.
US09592687B2 Head device, apparatus incorporating the head device, liquid discharge device, and apparatus for discharging liquid
A head device includes a head and a head holder. The head includes a reference face, a first opposing face, and a second opposing face. The head holder is joined to the head. The head holder includes a reference face contacting the reference face of the head, a first opposing face opposing the first opposing face of the head to form a first space, and a second opposing face opposing the second opposing face of the head to form a second space. The second space is smaller than the first space in a mounting direction in which the reference face of the head is brought into contact with the reference face of the head holder. The head is joined to the head holder with adhesive filled in each of the first space and the second space.
US09592686B2 Liquid ejecting apparatus and method of detection
A liquid ejecting apparatus includes: a supporting section capable of supporting a medium; an ejecting section capable of ejecting liquid onto the medium supported by the supporting section; and a first detecting section capable of detecting whether an amount of space between the medium supported by the supporting section and the ejecting section is equal to or more than a first threshold value. The liquid ejecting apparatus thus configured makes it possible to prevent liquid from being ejected from an ejecting section onto a medium in a state where an amount of space between the medium and the ejecting section is too large.
US09592683B2 Sheet supplying apparatus and printing apparatus
A sheet can be securely drawn out of a sheet roll irrespective of an outer diameter of the sheet roll, and then, can be conveyed. A driven roller moves according to the outer diameter of the sheet roll, so as to be brought into press-contact with an outer periphery of the sheet roll from below, with respect to the direction of gravity, irrespective of the outer diameter of the sheet roll. An arm member moves according to the outer diameter of the sheet roll, so as to guide a lower side of the sheet drawn through above the driven roller irrespective of the outer diameter of the sheet roll.
US09592672B2 Liquid ejecting apparatus
Provided is a liquid ejecting apparatus having a wiping device which performs a first wiping operation in which the first surface wipes the nozzle forming surface while setting a contact pressure of a wiper with respect to the nozzle forming surface to a first contact pressure, in a state where the pressurizing portion is driven and the pressure of liquid in the nozzles is set to be equal to or greater than atmospheric pressure and a second wiping operation in which the second surface wipes the nozzle forming surface wiped by the first surface while setting the contact pressure of the wiper with respect to the nozzle forming surface to a second contact pressure less than the first contact pressure.
US09592670B2 Liquid accommodating container, liquid ejecting device and liquid introducing method
There are provided a liquid accommodating container that has a sufficient volume for reserving waste ink and can accommodate therein a sufficient amount of ink used in printing with space-saving, a liquid ejecting device provided therewith and a liquid introducing method. Therefore non-print ink is discharged and reserved in a portion, in which unused ink for printing was reserved, in an ink tank for replacement of the unused ink.
US09592667B2 Printhead substrate and printing apparatus
A printhead substrate, comprising an electrothermal transducer configured to heat a printing material, a first DMOS transistor configured to drive the electrothermal transducer, a MOS structure forming an anti-fuse element, a second DMOS transistor configured to write information in the anti-fuse element by causing an insulation breakdown of an insulating film of the MOS structure, and a driving unit consisted of at least one MOS transistor and configured to drive the second DMOS transistor.
US09592665B1 Multiplexed multilevel converter amplifier
A multiplexed multilevel converter amplifier. The converter is configured to generate a converter voltage. The converter voltage varies among a plurality of voltage levels. A multiplexer is comprised of at least four switches configured to generate a positive output voltage and a negative output voltage according to a configuration of the at least four switches. The positive output voltage varies between the converter voltage and a positive supply rail and the negative output voltage varies between the converter voltage and a negative supply rail. An amplifier is supplied by the multiplexer, and the amplifier generates an output voltage that varies between the positive output voltage and the negative output voltage. A control module is configured to control the configuration of the at least four switches of the multiplexer and the plurality of voltage levels of the converter voltage, such that the converter voltage is synchronized with the output voltage.
US09592662B2 Method to damp an oscillation of a driven roller in a printing system
In a method to damp an oscillation of a roller driven via a drive in a printing system, a printing substrate web is directed across the roller, the roller and the printing substrate web forming a system capable of vibrating. With the drive the roller is driven with a predetermined nominal moment. With a sensor, a real value is determined of a variable representative of a velocity with which the printing substrate web is transported by the roller. In aid of a predetermined calculation rule, a correction moment is calculated from the determined real value such that a damping of the vibration-capable system results like a mechanical viscous damper. The correction moment is added to the predetermined nominal moment upon activation of the drive.
US09592660B2 Heated build platform and system for three dimensional printing methods
An apparatus performing as a base for printing 3D objects using high temperature thermoplastics employing additive manufacturing methods is provided. The apparatus comprises a heated build platform, a thin removable plate secured on top of the build platform, a high temperature polymer coating applied over the removable plate, and surface treatment of high temperature polymer coating to maintain adhesion between 3D object and printing surface. Also, the removable plate has low coefficient of thermal expansion compared to build platform below it, for avoiding bowing of the plate as it is heated due to heated build platform, hence providing flat printing surface. The thin removable plate allows 3D objects to pop off the plate upon cooling, without damaging the polymer coating, the plate, or the object. It also allows for continuous operation of printing, while the plate is released for cooling, a new plate is installed for printing.
US09592658B2 Laminate material having a decorative appearance and method of manufacture
A laminate material having a decorative appearance has a plurality of layers that are bonded together with at least one of the layers having a first orientation. A portion of at least one of the layers adjacent to an exterior surface of the material is deviated into a second orientation differing from the first orientation. The exterior surface of the material is substantially flat, thereby revealing multiple layers at the exterior surface. Each layer may comprise a sheet that is pre-impregnated with a thermosetting resin. A form having a surface feature may be pressed into the exterior surface of the material while the layers are bonded together to deviate a portion of at least one of the layers adjacent to an exterior surface of the material into the second orientation. The invention also includes a method of generating a laminate material having a decorative appearance.
US09592655B2 Method and apparatus for inline adhesive signage
A process to apply pressure sensitive adhesive to cut sheet media and eliminate a separate release liner. A Silicone release layer is applied (post fuser) on a top surface of the media and then UV cured. A pressure sensitive adhesive layer is applied next. The cut sheets are then stacked and a compressive force is applied that transfers the pressure sensitive adhesive from one sheet to another and helps hold the stack together.
US09592653B2 Polymer interlayers having improved optical properties
An interlayer comprised of a thermoplastic resin, at least one high refractive index plasticizer and, optionally, a conventional plasticizer. The use of a thermoplastic resin, a high refractive index plasticizer, and, optionally, a conventional plasticizer reduces or minimizes the optical defects caused by different refractive indices without sacrificing other characteristics of the interlayer.
US09592652B2 Heat-seal failure prevention apparatus
A co-injected molded multi-layer article has inner and outer layers, an interior layer contained within the inner and outer layers and a surface portion to which a closure or other component may be heat-sealed. The article is molded by co-injecting the inner, outer and interior layer materials into a mold cavity of a mold. The interior layer material is caused to flow along a steam line offset from the zero velocity gradient of the combined material flow and biased toward a material flow for forming an outer wall of the multi-layer article. The resultant molded multi-layer article contains an interior layer located in a heat sealable region that avoids a breach or failure during a heat seal operation to seal an opening of the molded article.
US09592647B2 Modular corrugated container having integrated cushioning
A modular corrugated container integrates product cushioning with a product support surface formed from corrugated paper and having features that absorb transverse accelerations. The support surface has scored tabs that bend perpendicular to an interior support portion, forming feet that elevate the interior portion relative to a container bottom. The interior portion has perforations that absorb accelerations, such as a perforations formed around the outside perimeter of the location at which a product rests, perforations extending from corners of the support surface towards a central location of the support surface, and perforations at the scoring of the tabs. Voids formed along the tabs remove portions of the feet from contact with the container bottom to encourage constant dissemination of accelerations across the support surface.
US09592642B2 Method for producing multi-layer polyethylene resin foam sheet
A method for producing a multi-layer foam sheet having a foam layer and a resin layer laminated on at least one side of the foam layer, includes coextruding a foamable molten resin composition which contains a low density polyethylene and a physical blowing agent and a molten resin composition which contains 80 to 20% by weight of a specific ethylene-propylene random copolymer and 20 to 80% by weight of a specific polyethylene resin so that the foamable molten resin composition forms the foam layer and the molten resin composition forms the resin layer.
US09592641B2 Tire sealant bottle assembly
A tire sealant bottle assembly that includes a bottle, a nozzle, and a cap is disclosed. The bottle is designed to hold tire sealant therein. The nozzle removably couples to the bottle and includes a nozzle base, a nozzle head integral with the nozzle base, and a channel extending through the nozzle. The channel includes a substantially cylindrical portion at the terminating end of the nozzle head that is at least 5 mm in length and has an inner diameter between approximately 7 and 8 mm. The cap may be a hollow valve core tool cap having an open first end, a closed second end, and a valve core removal tool extending from the second end away from the first end.
US09592639B2 System for cleaning cart drive components in three-dimensional object printing systems
A cart that helps eliminate contaminants from a printing system with a rail support track includes a platform, a first bearing, and a first blade. The first bearing is operatively connected to the platform, and is positioned and configured to roll along a first cylindrical rail of a rail support track of a printing system to enable the platform to move along the first cylindrical rail. The first blade has a leading edge oriented at an acute angle relative to a curved surface of the first cylindrical rail, and is configured to engage the curved surface to remove contaminant as the cart moves along the first cylindrical rail.
US09592638B2 Top drive mobile cart for three dimensional object printing systems
A mobile cart that moves through a three-dimensional object printing system includes a first member having a pair of surface that slide along a pair of tracks, a receiver mounted to the first member that moves the cart along the tracks, and a planar member that has a surface for forming a three-dimensional object, and that is connected to the first member. The planar member and the first member are configured to enable an ejector head positioned opposite the track to pass between the planar member and the first member as the cart moves along the track.
US09592631B2 Blow molding process and apparatus
In at least some implementations, a blow molding process provides that portions of the parison are engaged by one or more clamping devices disposed on or adjacent to the blow mold parts, and that the blow mold is opened whereby the parison is torn apart between the clamping devices, into two or more pieces of the parison. In other implementations, the clamping devices may be moved relative to the blow mold to tear the parison, or the parison may be torn by a combined movement of the blow mold parts and clamping devices.
US09592619B2 Device for processing or generating break lines in flat products
In a device for processing flat products using a processing tool which processes the product between the tool and a counter-tool, the processing tool is supported by an ultrasonic sonotrode. The processing tool performs a processing movement together with an ultrasonic sonotrode, wherein the processing movement results in a partial separation of the flat product.
US09592616B2 Knife that relieves pressure on metacarpophalangeal joint of index finger
A knife for relieving pressure on the index finger metacarpophalangeal joint of one using the knife by pressing down with the index finger on a top portion of the knife, comprising a handle having a top and bottom portion and two opposing sides and a proximal and distal end, a blade having a top portion and bottom, cutting edge portion and two opposing sides and a proximal and distal end and configured so the handle and blade overlap and the blade proximal end is connected to the handle distal end, a finger rest having a top and front portion and is connected to the blade at a point proximate the proximal end of the blade, and wherein the finger rest, handle and blade are configured to minimize pressure on the index finger metacarpophalangeal joint of one using the knife by pressing down with the index finger on the finger rest.
US09592613B2 Shaving head with multiple shaving units
A shaving head for an electric dry shaver includes a base element for carrying at least three cutter units. Each unit provides an outer cutter and an inner cutter arranged to be moved in sliding contact relative to each other. At least one cutter unit includes a foil-type outer cutter. The shaving head further includes a first trimmer-type cutting unit that has a plurality of slots defined by a plurality of adjacent bar elements featuring cutting edges. The shaving head also includes a second trimmer-type cutting unit having an outer cutter that includes a plurality of teeth featuring cutting edges and spaced apart from each other so as to define a plurality of slits.
US09592596B2 Drive-in device
In accordance with an aspect of the application, a device for the driving in of an affixing element into a substrate has an energy transfer element for the transfer of energy to the affixing element. Preferably, the energy transfer element can be moved between a starting position and a placement position, wherein the energy transfer element is located in the starting position before a driving-in process and in the placement position, after the driving-in process.In accordance with another aspect of the application, the device comprises a mechanical energy storage unit for the storage of mechanical energy. The energy transfer element is then preferably suited for the transfer of energy from the mechanical energy storage unit to the affixing element.
US09592594B2 Socket wrench with retaining mechanism
A socket wrench includes a wrench body, a driving seat and a retaining ring. The driving seat disposed in a head of the wrench body, and has a central hole, an aperture defined in and through an inner wall of the central hole, and a cutout defined in an outer periphery thereof. The retaining ring mounted around the driving seat has a hook portion and a straight leg. The hook portion has a distal end extending through the aperture of the driving seat. The straight leg is rested in the cutout of the driving seat. The straight leg has a distal end extending outside the cutout. The straight leg could be operated to an open position where the distal end of the hook portion is retracted in the aperture of the driving seat.
US09592593B2 Torsion-adjustable impact wrench
A torsion-adjustable impact wrench, includes a housing, a powering unit including an impact mechanism configured to generate an intermittently increasing torque, an adjusting unit configured to manually set a first torsion value and generate a corresponding a first torsion signal, a detecting unit configured to detect a rotational speed of the powering unit and generate a corresponding first rotational speed signal, and a control unit configured to generate a control signal for controlling the output of the rotational speed of the powering unit. The control unit generates a second rotational speed signal according to the first torsion signal outputted by the adjusting unit, compares the first rotational speed signal with the second rotational speed signal, and generates a control signal enabling the rotational speed of the powering unit to approach the second rotational speed.
US09592592B2 Anchor driver
A wedge anchor driver comprising: a first member having a first opening configured to fit onto the nut of a wedge anchor and a second opening configured to receive a predetermined length of the outer end of the wedge anchor's bolt; and a second member associated with the first member, wherein the second member's distal end is configured to fit, and be lockable, into the chuck of a hammer drill, such that, after the wedge anchor driver is locked into the chuck of the hammer drill, a user can drive the wedge anchor into a corresponding hole with the hammer drill in hammer mode and then tighten the nut of the wedge anchor by switching the hammer drill from hammer mode to drill mode.
US09592579B2 Clamping fixture
The invention relates to a clamping fixture comprising a chuck (1) and for locking thereto a workpiece pallet (2). The chuck (1) comprises first centering members in the form of centering spigots (5) whilst said workpiece pallet (2) is provided with a main body (20) and secured thereto a centering disk (23). The centering disk (23) is provided with second centering members in the form of centering openings (24). The centering spigots (5) of the workpiece pallet (2) are adapted to the centering openings (24) of the workpiece pallet (2) that the latter is alignable in the X-direction and Y-direction on clamping to the chuck (1). Provided topping the chuck (1) is a sealing member assembly (7). Disposed between the centering disk (23) and the main body (20) of the workpiece pallet (2) is a sealing disk (21) which overhangs the centering disk (23) radially. The portion of the sealing disk (21) overhanging the centering disk (23) radially is configured such that said portion sealingly comes into contact with a sealing member of the sealing member assembly (7) when clamping the workpiece pallet (2).
US09592575B2 Weld metal having excellent resistance to hydrogen embrittlement susceptibility
The weld metal of the present invention is formed by gas shield arc welding using a flux-cored wire, has a predetermined chemical component composition, and contains 20% or more of Ti. The amount of Ti-containing oxide particles having a circle-equivalent diameter of 0.15-1.0 μm is at least 5000 per square mm, the amount of V per total mass of weld metal present as a compound within the weld metal is 0.002% or more, and the average circle equivalent diameter of V-containing carbide present in the weld metal is 15 nm or less.
US09592569B2 Method and apparatus for forming visible indicium on the tab portion of a beverage container
A method and apparatus for forming a visible symbol or other indicium on a tab portion of a beverage container. The method comprises the steps of advancing a tab stock material through a series of tab-forming stations. The tab portion is at least partially formed from the tab stock at each of the tab-forming stations. The advancement of the tab stock is dwelled or halted while the tab is formed. The tab stock is accelerated from dwell to resume advancement of the tab stock material between the stations. A selected portion of the tab is irradiated with light energy to form the visible indicium. The apparatus comprises a plurality of tab-forming stations, each tab-forming station at least partially forming the tab from a tab stock. A conveyor or track mechanism is configured to advance the tab stock from one tab-forming station to another. An etching apparatus is associated with the conveyor and tab-forming stations to selectively etch the symbol on the tab. A sensor is coupled to the tab stock to sense acceleration of the tab stock from rest during advancement of the tab stock. The sensor is coupled to the etching apparatus to permit the etching apparatus to etch the symbol while the tab stock is accelerated.
US09592566B2 High current AC welder
A welding assembly and method is described which includes a charging circuit and regulator coupled to an input power source; an energy storage element connected in parallel with the charging circuit and regulator to increase the weld current output, wherein the energy storage element is charged by the charging circuit and regulator; and a weld output controller connected in parallel with the energy storage element for controlling a welding arc between an electrode and a workpiece, wherein the weld output controller includes a forward converter/inverter including a series circuit of a primary winding of a transformer, and a switching element which is coupled to the energy storage element, and a rectifier smoothing circuit which rectifies and smoothes a voltage induced in a secondary winding of the transformer according to a switching operation of the switching element, wherein the rectifier smoothing circuit conducts during an ON period of the switching element.
US09592565B2 Integrated electrical components of a welding power supply
A power supply includes an electrical component having at least one pin extending a first distance from a body portion of the electrical component to a circuit board. The power supply also includes a heat sink coupled to the body portion of the electrical component and extending substantially parallel to the at least one pin for approximately the first distance from the body portion to the circuit board. In one embodiment, the at least one pin of the electrical component is not trimmed during assembly of the power supply. In another embodiment, the power supply includes a heat sink hanging over an edge of the circuit board. Moreover, in certain embodiments, a transformer lead is coupled to a diode using a fastener.
US09592561B2 Stroke safety device for a key duplicating machine
A stroke safety device for a key duplicating machine has a fixed mount and a movable mount. The fixed mount is mounted around a connecting shaft of the key duplicating machine and has a first body, multiple first resilient members, multiple pressing elements, and an adjusting element. The first body has a through hole, an inclined segment, and a mounting recess. The movable mount is pivotally connected to the fixed mount and has a second body and an operating element. The second body is pivotally mounted on a base of the key duplicating machine to cover the inclined segment, and has two opposite side segments. The abutting rod is inserted into the mounting recess of the first body to selectively abut against the adjusting element.
US09592559B2 Manual drilling apparatus equipped with a device for control of advance
A manual drilling apparatus equipped with a device for control of advance, which includes a fixed part and a mobile part with movement of translation relative to the fixed part during the drilling, as well as a system for control of the movement of translation of the mobile part relative to the fixed part, wherein the fixed part and the mobile part comprise respectively at least one fixed tube and at least one mobile tube which slide relative to one another, the fixed and mobile tubes being coaxial to the axis of rotation of the tool supported by the apparatus.
US09592557B2 Chuck guard for lathe
A lathe or other rotating machine includes a chuck for holding a work piece or tool. The chuck is operated between grasping and releasing positions. A chuck guard is mounted on a housing of the rotating machine. The chuck guard has a transparent window and is mounted for pivoting movement between a position covering the chuck and a position exposing the chuck. A chuck guard extension with a window is attached at a front lower end of the chuck guard.
US09592553B2 Method for manufacture of a HIP consolidated component and a HIP:ed component comprising a wear resistant layer
A method for manufacturing of a wear resistant component including the steps of providing a form defining at least a portion of the shape of the component; providing a powder mixture comprising 30-70 vol % of a powder of tungsten carbide and 70-30 vol % of a powder of a nickel based alloy, wherein the nickel based alloy consists of, in weight %: C: 0-1.0; Cr: 0-14.0; Si: 2.5-4.5; B: 1.25-3.0; Fe: 1.0-4.5; the balance being Ni and unavoidable impurities, and wherein the powder of tungsten carbide has a particle size of 105-250 μm and the powder of the nickel based alloy has a maximum particle size of 32 μm; filling at least a portion of the form with the powder mixture; and subjecting the form to Hot Isostatic Pressing at a predetermined temperature, a predetermined isostatic pressure and a for a predetermined time so that the particles of the nickel-based alloy bond metallurgically to each other.
US09592552B2 Method of neutralizing amine gas odor in cold box process, and amine gas generator using the same
A method of neutralizing an amine gas odor in a cold box process, and an amine gas generator using the method are disclosed. The method includes: making molding sand by mixing sand and forming resin; putting the molding sand into a mold; hardening the molding sand by injecting an amine gas into the molding sand in the mold; and removing an amine gas odor remaining in the mold by injecting an amine gas odor neutralizer into the mold. Accordingly, it is possible to inject an amine gas odor neutralizer in casting of a core or a mold in order to reduce the amine gas odor that remains and leaks through a gap of a mold in the casting. Further, an odor neutralizer is immediately injected simultaneously with discharging of an amine gas, so it is possible to simply remove an odor.
US09592551B2 Metal transfer trough
A trough for cooling and delivering molten metal to a casting station. The trough comprises a refractory portion for holding the molten metal and heat transfer means associated to external walls of the refractory portion for extracting heat from the molten metal. The heat transfer means may comprise a fluidized bed compartment for holding and fluidizing a fluidization material. Also, the heat transfer means may comprise a cooling jacket, an inner wall of the cooling jacket and the external walls of the refractory portion defining the fluidized bed compartment.
US09592549B2 Thermally directed die casting suitable for making hermetically sealed disc drives
A hermetically sealed disc drive comprising at least one aluminum alloy housing component manufactured with a thermally directed die casting press subassembly is disclosed. In one embodiment, the thermally directed die casting press subassembly comprises a thermally directed funnel gate that is skewed to sample molten material from an off-center portion of the shot sleeve. Disc drive housing components can be manufactured by injecting an aluminum alloy slurry from the shot sleeve through the thermally directed funnel gate and the injection nozzle into the die cavity. The aluminum alloy slurry may be a thixotropic slurry comprising a uniform primary aluminum particle size in the range of approximately 50 to 80 microns. The primary aluminum particles of cast products produced according to the methodology of the present disclosure, with the aforementioned particle size distribution, are free of encapsulated eutectic at the micron scale.
US09592548B2 Calcium hexaluminate-containing mold and facecoat compositions and methods for casting titanium and titanium aluminide alloys
The disclosure relates generally to mold compositions and methods of molding and the articles so molded. More specifically, the disclosure relates to mold compositions, intrinsic facecoat compositions, and methods for casting titanium-containing articles, and the titanium-containing articles so molded, where the mold comprises calcium hexaluminate.
US09592544B2 Draw forming method
A draw bead is formed in a plate-shaped material in which a drawn portion is formed, outside the drawn portion, the draw bead being used to adjust an inflow of the plate-shaped material into a drawing die. The drawn portion is drawn in the plate-shaped material by using the draw bead as formed. The draw bead is crushed and flattened after the drawn portion is drawn.
US09592543B2 Portable gas monitor
A portable monitor used to measure landfill gas and landfill well parameters. The portable monitor includes a control unit and a measuring unit that can communicate wirelessly with one another. The control unit and/or measuring unit can include a heating arrangement to increase the temperature of one or more components in the control unit and/or measuring unit in cold environments.
US09592542B2 Method and apparatus for cleaning the interior of an above ground storage tank
An apparatus and method for cleaning the interior of an above ground storage tank includes a nozzle assembly mounted to a cover on the storage tank sidewall having a horizontally extending wash pipe fixedly and a suction pipe for recirculation of spent fluids. The wash pipe has an interior segment which can be extended to a tank floor and is configured with a bend to extend along the tank sidewall to which is attached a submersible swivel joint fitted with a choked nozzle. The nozzle assembly is attached to a control assembly so that the direction of flow from the nozzle may be manipulated by rotation of the swivel joint from the exterior of the storage tank. The nozzle also may be adjusted so the direction of flow may follow the angle of the tank floor.
US09592538B2 Compact and modular robotic wash system
A compact robotic wash system is provided for cleaning a work piece. The robotic wash system includes an enclosed wash chamber. A robot is fully disposed inside the wash chamber. The robot has a maximum horizontal reach that is at least 40% of the maximum horizontal linear dimension of the wash chamber. The robot may hold a work piece and move the work piece around a plurality of spray devices. Alternately, the robot may hold one or more spray devices, while a work piece is supported on a movable table.
US09592537B2 Residue removal device for narrow necked vessels
The present disclosure relates to a residue removal device for extracting leftover material from a narrow-necked vessel. The residue removal device may include a receptacle adapted for collecting material from sides and bottom of a vessel. The receptacle may include a material collecting channel formed by two side walls connected along a base at an angle, an open top, a distal end, and a proximal end. The residue removal device may further include an elongated shaft having a proximal end and a distal end, and the distal end of the shaft may be connected to the base of the receptacle and offset in a first direction from the proximal end of the shaft. The open top may also be offset from the base of the receptacle in the first direction.
US09592536B2 Surface cleaning
There is herein described an improved contact cleaning surface and an improved method for cleaning surfaces. More particularly, there is described a contact cleaning surface comprising a micro-structured surface adapted to collect and/or remove microscopically sized contaminating material from a contaminated surface.
US09592533B2 Process for tin coating a metallic substrate, process for hardening a tin layer and wire having a tin coating
The present invention is directed to a process for tin coating a metallic substrate, and a process for hardening a tin layer and wire having a tin coatingThe invention relates in particular to a process for tin coating a wire. In the process, firstly a tin layer is applied, and a metal layer made of a metal different to tin is applied thereto. Then, the layers are subjected to a diffusion annealing operation.
US09592532B2 Textured surfaces to enhance nano-lubrication
Embodiments of the present invention may provide textured surfaces to be lubricated, the texturing to enhance the effectiveness of the intended nano-lubrication. The texturing may make asperities and depressions in the surface to be lubricated. This texturing may be executed, for example, by chemical etching, laser etching, or other techniques. This texturing may create locations in the lubricated surface to hold or anchor the intended nano-lubricants, to facilitate the creation of a tribo-film on the surface when the lubricated surface is used under pressure, and resulting in delivery of multiple chemistries from the nano-lubricant.
US09592531B2 Ink curing apparatus
An ink curing apparatus comprising a lamp housing with a lamp fitting for a lamp terminal of a UV lamp at each opposing end, wherein at least one of the lamp fittings is non-conducting and has a non-conducting lamp terminal seat which has a concave profile for receiving a substantially spherical lamp terminal end piece; whereby, in use during the fitting or removal of a lamp, the at least one lamp fitting allows a lamp terminal end piece to rotate about multiple axes, while being retained substantially in position at the lamp fitting.
US09592527B2 Spray texture material compositions, systems, and methods with accelerated dry times
A system for dispensing texture material in an orange peel pattern has an aerosol dispenser and a contained material. The aerosol dispenser is a container assembly, a valve assembly, and an outlet assembly. The contained material is texture material and propellant material. The texture material comprises water as a solvent/carrer, latex binder, fillers, and drier accelerant. The outlet assembly alters the cross-sectional of the outlet opening to correspond to a desired orange peel texture pattern. The valve assembly allows the propellant material to force at least a portion of the texture material out of the outlet opening in a spray pattern corresponding to the desired orange peel texture pattern. The drier accelerant promotes drying of the dispensed texture material.
US09592524B2 Coating device comprising a jet of coating medium which is broken down into drops
A coating device comprises at least one application apparatus to discharge a coating agent from at least one coating agent nozzle. The application apparatus is configured to apply an oscillation to at least one of the coating agent and at least one coating agent jet such that at least one of the coating agent and the at least one coating agent jet break up into droplets.
US09592522B2 Multilevel paint shop for painting objects
To provide a paint shop for painting objects to be painted in the form of vehicle bodies and/or parts of vehicle bodies, there is proposed a paint shop for painting objects to be painted in the form of vehicle bodies and/or parts of vehicle bodies which comprises the following: a building shell, which encloses a building interior, in which are arranged at least one dip tank and at least one open treatment area, which is open in relation to the building interior; a first transport level, on which objects to be painted can be transported through at least one open treatment area; a second transport level, from which objects to be painted can be dipped into at least one dip tank; and at least one intermediate storage unit, wherein at least one object to be painted can be transported from one transport level of the paint shop into the intermediate storage unit and later can be transported out of the intermediate storage unit into another transport level of the paint shop.
US09592521B2 Drain wand
A drain wand includes an elongated wand body having an outside diameter of approximately ¼ inches. The wand body includes a first end that houses a water inlet unit and a valve controller. A sprayer is disposed along the second end of the elongated wand and is connected to the inlet unit and controller via an internal channel. The sprayer includes an elongated longitudinal opening that functions to discharge water at a generally perpendicular angle to the wand and at approximately 125 psi.
US09592519B2 Dual position external charge ring and dual pre-orifice restriction on a dual purge system
A charge ring and fluid restriction arrangement for a paint spray tool. The paint spray tool has a charge ring that is moveable along the axis of the tool body. The paint spray tool also has interchangeable pre-orifices within the tool body.
US09592512B2 Gyratory crusher spider arm shields
A gyratory crusher includes a spider supported at a top shell, the spider having a pair of spider arms protected by respective arm shields. The shields are mounted and dismounted at the respective arms via a locking flange and notch and lug arrangement to avoid attachment by welding or attachment bolts.
US09592508B2 Systems and methods for fluid handling
Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.
US09592507B2 Integrated cartridge housings for sample analysis
The invention relates to a cartridge housing for forming a cartridge capable of measuring an analyte or property of a liquid sample. The housing including a top portion having a first substantially rigid zone and a substantially flexible zone, a bottom portion separate from the top portion including a second substantially rigid zone, and at least one sensor recess containing a sensor. The top portion and the bottom portion are bonded to form the cartridge having a conduit over at least a portion of the sensor. The invention also relates to methods for forming such cartridges and to various features of such cartridges.
US09592506B2 Method of crystallization in aqueous plugs flowing in immiscible carrier-fluid in microfluidic system
A method of crystallization is disclosed, the method comprises the steps of providing a microfluidic system comprising at least three channels having at least one junction; providing within the at least three channels a continuously flowing water-immiscible carrier-fluid, a continuously flowing first aqueous fluid comprising a crystallization target, and a continuously flowing second aqueous fluid comprising a precipitant; forming at least one plug comprising the first and second aqueous fluids by partitioning the aqueous fluids with the flowing carrier-fluid at the junction of the at least three channels, flowing the at least one plug through an outlet port into a tubing, and stopping the flow of the at least one plug in the tubing, wherein the crystallization target forms a crystal in the tubing.
US09592499B2 Process for the isolation of carotenoids
Described herein is a material for reversibly binding to a carotenoid comprising a support coupled to silver ions in an amount to enable reversible binding with carotenoids, and wherein with the exception of silver ions, is substantially free of transition metals. Also described herein is a process for reversibly binding a carotenoid, the process comprising the steps of: providing a support coupled to silver ions in an amount to enable reversible binding with the carotenoid, wherein with the exception of silver, the support is substantially free of transition metals, contacting the support with the carotenoid under binding conditions to bind it thereto and dissociating the carotenoidod from the support under dissociating conditions to release the carotenoid.
US09592495B2 Ammonia synthesis catalyst
An ammonia synthesis catalyst synthesizing ammonia from nitrogen in a presence of moisture is provided. The ammonia synthesis catalysis includes a catalyst particle including an inorganic material that has a photocatalytic function and an inorganic acid. The catalyst particle is preferably an n-type semiconductor and includes oxide material including at least titanium preferably. The inorganic acid preferably corresponds to at least one of perchloric acid, hydrochloric acid, sulfuric acid, and phosphoric acid.
US09592493B2 Forming silver catalytic sites from silver phosphite carboxylates
A non-aqueous metal catalytic composition includes (a) a silver carboxylate-trialkyl(triaryl)phosphite complex comprising reducible silver ions in an amount of at least 2 weight %, (b) a silver ion photoreducing composition in an amount of at least 1 weight %, and (c) a photocurable component or a non-curable polymer or a combination of a photocurable component and a non-curable polymer. This non-aqueous metal catalytic composition can be used to form silver metal particles in situ during suitable reducing conditions. The silver metal can be provided in a suitable layer or pattern on a substrate, which can then be subsequently subjected to electroless plating to form electrically-conductive layers or patterns for use in various articles or as touch screen displays in electronic devices.
US09592490B2 Glass catalysts for soot combustion and methods of manufacturing the same
A simplified method of manufacturing a catalyst for soot combustion includes the synthesis of a catalyst composition. A substrate is prepared for receipt of the composition and a sol solution is created utilizing the composition synthesized. Finally, a catalytic coating is applied to the substrate, through use of the sol solution. The catalyst composition may be any suitable composition including a K2O, CaO, SiO2 (KCS-1) silcate catalyst, and the substrate may be a wire mesh, such as for example, a commercial metallic wire mesh. The application of the coating to the substrate, may be performed through any suitable coating process including, for example, a sol-gel dipping process, spraying, painting, etc.
US09592489B2 Metal-adsorbing gel and adsorbent supporting metal-adsorbing gel
ProblemThe present invention provides, in a metal-adsorbing material used for the removal and recovery of a wide range of heavy metals in treated solutions such as industrial waste water, service water, and environmental water, a gel-like metal-adsorbing material having a large amount of metal adsorption and capable of meeting various demands; and also provide a metal adsorbent having a gel-like metal-adsorbing material supported on a porous carrier.Means for ResolutionA metal-adsorbing polymer selected from polyethyleneimine and polyallylamine is crosslinked with a polyglycidyl ether, whereby a gel-like metal-adsorbing material having a large amount of metal adsorption and capable of meeting various demands is produced. Further, a hydrophilic porous carrier is impregnated with a metal-adsorbing polymer, followed by crosslinking with a polyglycidyl ether, whereby a metal adsorbent having a gel-like metal-adsorbing material supported on the porous carrier, which has a large amount of metal adsorption and can meet various demands, is produced.
US09592486B2 Olefin polymerizer, polyolefin production system, and process for producing polyolefin
An olefin polymerization reactor comprising a tubular portion that extends in a vertical direction; a tapered portion disposed inside the tubular portion, an inside diameter of the tapered portion decreasing downwardly, and including a vertically penetrating orifice at a bottom end thereof; a tubular lower deflector disposed above the orifice of the tapered portion, an outside diameter of the tubular lower deflector increasing downwardly, a bottom end thereof being located away from an inner wall of the tubular portion, and including a vertically penetrating orifice at a top end thereof; and an upper deflector disposed above the orifice of the lower deflector, an outside diameter of the upper deflector increasing downwardly, a top end thereof being closed, a bottom end thereof being located away from the inner wall of the tubular portion, and an outside diameter at the bottom end being equal to or greater than an inside diameter of the orifice of the lower deflector.
US09592483B2 Fluid mixing and rinsing system for a flow cytometer
Disclosed is a system that can mix deionized water and concentrated sheath fluid to provide sheath fluid in a flow cytometer system having a desired concentration. Flow rates are low, which substantially match the flow rate of sheath fluid through the nozzle, so that turbulence and air bubbles are not formed in the sheath fluid. The available deionized water is then used for back flushing and removal of sample cells and deposited salts from the sheath fluid.
US09592480B2 Inner premix tube air wipe
An inner premix tube for a fuel injector of a gas turbine engine includes a transition end, a tip end, and a premix tube inner surface. The transition end includes an annular disk portion with an annular disk shape and a redirection portion extending radially inward and axially from the annular disk portion. The transition end also includes a plurality of wipe passages extending through the transition end. The tip end includes a cylindrical portion with a hollow right circular cylinder shape. The premix tube inner surface is a radially outer surface including the redirection portion outer surface and the cylindrical portion outer surface.
US09592477B2 Membrane comprising self-assembled block copolymer and process for producing the same by hybrid casting (Ib)
Disclosed are membranes formed from self-assembling diblock copolymers of the formula (I): wherein R1-R4, n, and m are as described herein, which find use in preparing porous membranes. Embodiments of the membranes contain the diblock copolymer that self-assembles into a cylindrical morphology. Also disclosed is a method of preparing such a membrane which involves hybrid casting a polymer solution containing the diblock copolymer to obtain a thin film, followed by evaporation of some of the solvent from the thin film, and coagulating the resulting this film in a bath containing a nonsolvent or poor solvent for the diblock copolymer.
US09592475B2 Method for forming perforated graphene with uniform aperture size
A method of forming a filter with uniform pore sizes includes synthesizing a moiety so as to form a plurality of like platelets having a precisely sized pore extending therethrough, distributing the plurality of like platelets about a membrane having apertures therethrough, and bonding the plurality of platelets around the apertures to form precisely sized pores through the membrane. A filtration membrane is also disclosed which provides a porous membrane having a plurality of apertures therethrough, and a plurality of platelets, wherein each platelet has a pore therethrough. The platelets are positioned over or in the apertures.
US09592474B2 Ultrafiltration membranes and methods of making
The present invention is an integral multilayered composite membrane having at least one ultrafiltration layer made by cocasting or sequentially casting a plurality of polymer solutions onto a support to form a multilayered liquid sheet and immersing the sheet into a liquid coagulation bath to effect phase separation and form a multilayered composite membrane having at least one ultrafiltration layer.
US09592468B2 Partitioned distributor tray for offshore gas/liquid contact column
The invention is a distributor tray for a column (1) for heating and/or material exchange between a gas (G) and a liquid (L). At least one wall (6) defines compartments (8) on one of the surfaces of the tray. The walls are perforated (7) to allow part of the liquid to flow between compartments (8). Each compartment has a passage providing flow of the liquid through the tray and for a passage providing flow of the gas through the tray. The invention also relates to a gas/liquid contact column, a gas treatment unit, a CO2 capture unit, a distillation unit, and an offshore floating barge including the distributor tray. The invention also relates to a method of manufacturing the tray.
US09592465B2 Filter material
A filter material for an air filter may include a substrate layer on an inflow side and a fine-fiber layer on an outflow side relative to a flow direction. The filter material may include a connection region arranged between the substrate layer and the fine-fiber layer. The substrate layer, connection region and fine-fiber layer may include pores having an aggregate degressive pore size with respect to the flow direction. A combined thickness of the substrate layer, connection region and fine-fiber layer may be at least 0.35 mm. The substrate layer may include a cellulose material and have an impregnation of resin disposed along the inflow side. The resin may amount to approximately 22% by mass of the substrate layer.
US09592464B2 HVAC filtration system
This invention pertains to interchangeable, disposable, air filtration pads, which work in conjunction with its double-sided flexible magnetic gaskets and mats. This system works both for return and supply side of the HVAC system. This multi-adaptable double-sided magnetic mat system is easily attachable and removable and compatible to current factory vent plates, and HVAC systems.
US09592463B2 Tool-less auto-aligning filter retention system
A filter retention system for releasably retaining a filter cartridge in an operable position within air supply and air exhaust systems is comprised of a filter cartridge, filter retainers, mounting frame with integral sealing knife edge and filter alignment brackets. The filter retainers allow for installation and removal of the filter cartridge without the use of tools. The retention system automatically aligns filter cartridges such that an airtight seal is created between the sealant containing groove in the filter cartridge and the sealing knife edge of the retention system.
US09592461B2 Filter element and fuel filter
The invention concerns a filter element (1), in particular of a fuel filter for motor vehicles. The filter element (1) is received in a filter housing (2) and comprises a filter body (3) with a filter material (5) that is arranged in folds (4). Between two folds (4) a heater installation space is provided and configured to receive a heating element (6) for the fuel.
US09592454B2 Interactive waterslide system and method
An interactive amusement attraction capable of sensing ride vehicle or user interaction or position. The attraction can track user performance and/or location, through use of a ride vehicle or without, and can include a slide for supporting water and a sensor connected with the slide for sensing an interactive element. The tags or interactive element may be passive (e.g., sensed by the sensor merely when within a predetermined proximity) or may require user manipulation (e.g., a button to be pressed when within a predetermined proximity of the sensor). Various lighting elements may be connected or embedded in the slide and may be controlled to illuminate with various colors. These lighting elements, such as LED light strips, can be used to indicate the presence of a sensor and/or that a sensor has been successfully or unsuccessfully interacted with.
US09592452B2 Combination computing device and game controller with flexible bridge section
A device generally directed to a combination computing device and input device. The computing device provides a plurality of sides. The input device providing a structural bridge, and a pair of control modules. The pair of control modules confine the computing device on at least two opposing sides of the plurality of sides. The pair of control modules adaptively and snugly accommodate the width of the computing device, and alternatively, adaptively and snugly accommodate a width of a second computing device, the second computing device having a width greater than the width of the computing device. The structural bridge secures the pair of control modules one to the other, and adaptively and snugly accommodate the length of the computing device and alternatively, adaptively and snugly accommodate a length of the second computing device, the second computing device having a length greater than the length of the computing device.
US09592451B2 Directed communication in a virtual environment
The present invention relates to directed communication between avatars in a virtual environment controlled by end-users from outside the virtual environment. A method in accordance with an embodiment includes: determining a relative location of a first avatar and a second avatar in a virtual environment, wherein at least one end-user of the first avatar and the second avatar wears a headset configured to track head movements thereof, wherein the head movements of the end-user translate to their avatar and influence volume of voice communication from their avatar; adjusting aspects of a voice communication between the first avatar and the second avatar based on the relative location and the track head movements; referring to a list of avatars whose audio characteristics are to be portrayed differently in a voice communication; and further adjusting the audio characteristics of one of the first avatar and the second avatar in accordance with the list.
US09592449B2 Gaming system and method of gaming for controlling the display of appearance characteristics of an avatar
Disclosed is a gaming system comprising a display and a game controller, the game controller being arranged to identify a player from received player identification data, receive associated player game data of the identified player, and control the display of one or more characteristics of, or associated with, an avatar such that the player is provided with a graphical representation of the player game data. A method of gaming is also disclosed.
US09592446B2 Electronic game providing device and non-transitory computer-readable storage medium storing electronic game program
Play information storing play information about an electronic game is transmitted to a client. In response to access from the client, the game effectiveness of the electronic game for a user having accessed from the client is determined. When the game effectiveness for the user holds true, an operation of the electronic game by the user is allowed. When the game effectiveness for the user does not hold true, an operation of the electronic game by the user is not allowed.
US09592444B2 Method for implementing a computer game
A method, implemented as computer code being executed by one or more processors, in which computer game graphics for a casual, social game are shown on a display of a computing device, where the casual, social game is downloaded as an app to a smartphone and/or tablet computer and can be accessed or played using a social network application or environment; and in which one or more of the processors are programmed such that: a notification is automatically generated if a player is stuck at a level for more than a defined time or after more than a defined number of attempts to pass that level, the notification alerting friends of the player so that they can assist him or her.
US09592443B2 Data store for a modular assembly system
A data store for a modular assembly system is described. The data store comprises a number of records, each record relating to a physical module in the modular assembly system and comprising a module ID, an owner ID for the module and one or more properties fields. The properties field(s) define any property of the module and different records may define different properties. At least one of the fields in each data record (e.g. the module ID or owner ID) is verified by an authentication service. A user assembles two or more modules into a coherent physical whole object to act as a user input device to an interactive software experience. The data store communicates with the interactive software experience and causes a change in behavior of the interactive software experience in response to a check of the data records for each of the modules in the object.
US09592438B2 Binding system for recreational board
A binding system is mounted atop a rider-support surface of the board. The binding system comprises: a pair of rails locatable on opposing sides of a generally flattened foot-receiving surface for the rider's foot, each rail comprising a central portion mountable to the recreational board, a toe-side leg which extends from the central portion toward a toe-side of the recreational board and a heel-side leg which extends from the central portion toward a heel-side of the recreational board. Each rail is moveably coupled to a corresponding stand-off flange of a base.
US09592435B1 Attachable golfing aid
An attachable golfing aid is operable to provide a reference for a golfer during a swing. The attachable golfing aid includes an attachable component that is attachable to a body of the golfer or a shirt of the golfer. The attachable golfing aid also includes an outwardly extending visual aid that extends outwardly from the shoulder of the golfer when the attachable component is attached to the body of the golfer or the shirt of the golfer wherein the outwardly extending visual aid is configured to indicate an alignment and/or position of the golfer's shoulder before, during, and/or after a swing of the golfer.
US09592432B2 Gaming system and related method
An exemplary gaming system, in one implementation, provides active interaction between one or more players and the gaming system. Such an exemplary gaming system includes a receptacle with one or more holes to receive first gaming objects thrown at it. Chambers attached to a rigid member on the receptacle receive and store second gaming objects that are later released into one or more different spatial directions. An intermediate surface operably connected to a mechanical or an electrical triggering mechanism is included in the receptacle. When the first gaming object falls into the receptacle and hits the intermediate surface, the intermediate surface causes activation of the triggering mechanism to directly or indirectly propel the second gaming objects, through the chambers, into one or more different spatial directions. A hand or foot lever allows players to reset the triggering mechanism for the next game.
US09592431B2 Gaming system and related method
An exemplary gaming system, in one implementation, provides active interaction between one or more players and the gaming system. Such an exemplary gaming system includes a receptacle with one or more holes to receive first gaming objects thrown at it. Chambers attached to a rigid member on the receptacle receive and store second gaming objects that are later released into one or more different spatial directions. An intermediate surface operably connected to a mechanical or an electrical triggering mechanism is included in the receptacle. When the first gaming object falls into the receptacle and hits the intermediate surface, the intermediate surface causes activation of the triggering mechanism to directly or indirectly propel the second gaming objects, through the chambers, into one or more different spatial directions. A hand or foot lever allows players to reset the triggering mechanism for the next game.
US09592429B1 Tennis court ball retainer
A tennis court ball retainer having a horizontally extending ball gutter along the tennis court back wall which has an upwardly facing channel dimensioned to receive and retain tennis balls. An upright flexible upper backdrop curtain coextends directly above and along the ball gutter for engaging tennis balls striking the upper curtain, thereby dampening the tennis ball impact and directing the engaged tennis balls to fall into the ball gutter for retention. A tennis court floor surface ball retainer is also provided and coextends with and under the ball gutter. The ball gutter extends a uniform distance above the tennis court floor surface and includes an upright flexible lower backdrop curtain coextending below and along the ball gutter for engaging and trapping tennis balls striking this lower curtain by rolling or skidding on the tennis court floor surface. The lower curtain is draped to provide a sagging horizontal droop therein which is positioned a predetermined distance above the tennis court floor surface wherein this distance is dimensioned for thereby capturing and retaining tennis balls between the droop and the tennis court floor surface.
US09592427B2 Ball for ball game
A golf ball includes a spherical body and intersection surfaces. The intersection surfaces intersect with a spherical surface centered on the center of the spherical body, and are formed as conductive intersection surfaces having conductivity. The spherical surface is formed to have a smaller diameter than a diameter of the spherical body, and the conductive intersection surface is formed on an outer side in the radial direction of the spherical surface. The intersection surfaces intersect with a spherical surface centered on the center of the spherical body, and are formed as conductive intersection surfaces having conductivity. The conductive intersection surface is formed by both side surfaces of the annular body, and so the conductive intersection surface is formed to be continuous around the entire circumferential length of the spherical surface in the circumferential direction.
US09592423B2 Measuring system and measuring method for analyzing knee joint motion trajectory during cycling
A measuring system for analyzing a knee joint motion trajectory when a rider is riding a bike (cycling) and a measuring method thereof are disclosed. The measuring system includes a pedal-able device, a light emitting component fixed at a tibial plateau of the rider, an image capturing device, and a knee joint motion trajectory analysis device. When the rider continuously pedals the pedal-able device, the image capturing device captures an image of a central position of the rider's lower limb and a light spot trajectory image of the light emitting component. The motion trajectory analysis device generates an ellipse motion trajectory diagram. After comparing and analyzing a body central line with a trajectory long axis line, a foot force distribution and a shifting data of the knee joint motion trajectory is acquired, and a proper insole is determined.
US09592420B2 Resistance band bench and resistance band orienting and securing device
An exercise bench is provided that facilitates exercises performed with a resistance band. The exercise bench includes a supporting frame and a back support member and a seat support member attached to the frame. The back support member is selectively movable to different angles relative to the seat support member. At least one resistance band securing device attaches to one or both of the supporting frame and the back support member. The resistance band securing device selectively securing the resistance band to the exercise bench. At least one resistance band orienting member adjusts an angle of the resistance band relative to the resistance band securing device.
US09592417B2 Multi-purpose fitness device
The multi-purpose fitness device is provided in a comfortable posture such as being seated, face up or face down, to generate twisting of various body sites, loosen muscle stiffness in hypokinetic people, and promote blood circulation intermixed with muscle training, for recovery, maintenance and promotion of health. Dieting, rehabilitation, massage, stretching, cellulite prevention, and metabolic syndrome prevention exercise are addressed. For generating twisting in various body sites, the multi-purpose fitness device comprises: main body having a rotatably supported strut, a repetitive drive unit connectably disposed below the strut, upper and lower wings fixed to both side surfaces of struts, and a pad driver slidably connected on the top part of strut; and pad parts as accessories. By flexibly transmitting rotation of the main body units movable front-to-back, left-to-right and up-and-down to a human body, twisting exercises become possible in exercise bodily free positions.
US09592414B1 Field-deployable hydrolysis system
A transportable and modular field-deployable hydrolysis system for neutralizing toxic chemical agents is described. The system comprises a transportable chemical process plant that is capable of operating in a remote location without significant site infrastructure. The system is also capable of operating in a maritime, shipboard environment. A flexible design allows processing of chemical agents in both batch and continuous flow modes, as well as collection and accumulation of agents from a variety of containers whose form and size may not be known until the system is on-site.
US09592406B2 Equipment for producing ultraviolet light
Equipment including a lamp for producing UV light in the range 300-314 nm wavelength having spectral power in the range 302-307 nm wavelength across a 5 nm bandwidth of 40% of overall spectral power and spectral power in the range 307-312 nm of 40% of overall spectral power with a reflector of 90% reflectance in the range 300-314 nm wavelength. A key operated arming switch is series connected to a timer switch.
US09592399B2 Deployable multi-electrode leadless electrostimulator
An intravascularly-deliverable electrode assembly can be used to provide electrostimulation. The electrode assembly can include an electrostimulation circuit located in a housing, two or more elongate members coupled to the housing and configured to anchor the housing to a heart, the two or more elongate members including two or more electrodes electrically coupled to the electrostimulation circuit and controllably addressable by the electrostimulation circuit for delivery of an electrostimulation to the heart. The two or more elongate members can be sized and shaped for intravascular delivery to the heart in a first configuration, and in response to a user actuation, the two or more elongate members can move to a second configuration that is expanded relative to the first configuration to securely anchor the intravascularly-deliverable electrode assembly to the heart. Circuitry within the electrode assembly can coordinate electrostimulation, such as for delivery to sites near each electrode.
US09592396B2 Biocompatible bonding method and electronics package suitable for implantation
The invention is directed to a method of bonding a hermetically sealed electronics package to an electrode or a flexible circuit and the resulting electronics package that is suitable for implantation in living tissue, for a retinal or cortical electrode array to enable restoration of sight to certain non-sighted individuals. The hermetically sealed electronics package is directly bonded to the flex circuit or electrode by electroplating a biocompatible material, such as platinum or gold, effectively forming a plated rivet-shaped connection, which bonds the flex circuit to the electronics package. The resulting electronic device is biocompatible and is suitable for long-term implantation in living tissue.
US09592395B2 Electrical isolation in an implantable device
A total implantable hearing aid system is described. The system includes a single transformer that acts as an insulator between simulation circuitry and associated electrodes, and other system elements residing in the tissue. These other system elements include an RF receiver coil, a microphone system, a battery, and a digital signal processor. The transformer also increases the battery output voltage to a level needed by the simulation circuitry with electrodes.
US09592393B2 Leadless pacemaker with end-of-life protection
A leadless cardiac pacing system includes first and second leadless pacing seeds configured to deliver pacing therapy to a first and second location in a patient, respectively. The second seed includes an electrode, a therapy circuit configured to provide electrostimulation energy to the electrode, a communications component, and a power source. The second seed also includes a power manager configured to detect an end-of-life condition associated with the seed and, in response to detecting the end-of-life condition, to communicate a signal that causes the first seed to change from a first operational state to a second operational state, in which the first seed implements one or more operational parameters configured to adapt to a change in an output from the second seed resulting from the second seed entering the end-of-life condition.
US09592391B2 Systems and methods for detecting cardiac arrhythmias
Systems and methods for coordinating detection and/or treatment of abnormal heart activity using multiple implanted devices within a patient. In one example, cardiac activity may be sensed by two or more medical device, including a leadless cardiac pacemaker. Cardiac activity sensed by one of the implanted devices may be communicated to another one of the implanted devices. Abnormal heart activity may then be determined based on the cardiac activity of both of the medical device.
US09592390B2 Ventricular pacing to augment atrial natriuretic hormone production
Intermittent delivery of ventricular pacing pulses synchronized to occur during an atrial diastole time period can be used to provide atrial stretch therapy and augment the production and release of atrial natriuretic hormone.
US09592384B2 Method for the desynchronization of neural brain activity
A method is disclosed for desynchronizing neuronal brain activity of a patient in which the brain activity involves a neuron population firing in a synchronized manner. The method includes measuring a pathological frequency g of the neuronal brain activity of the patient, where the pathological frequency g relates to a pathological disorder of the patient. The method further includes calculating a stimuli frequency f based on the measured pathological frequency g, where the stimuli frequency f is calculated as being equal to the measured pathological frequency g×n/m, where n is 1, 2 or 3 and m is 1, 2 or 3, and controlling an electrode to generate stimuli in sequence with the stimuli succeeding each other at the stimuli frequency f, where the stimuli stimulate the neuron population of the patient.
US09592382B2 Systems and methods for rendering a customized acoustic scene for use in fitting a cochlear implant system to a patient
An exemplary system includes 1) a fitting facility configured to maintain data representative of a library of one or more sounds and data representative of a library of one or more environments, and 2) a detection facility configured to detect a selection by a user of a sound included in the library of one or more sounds an environment included in the library of one or more environments. The fitting facility is further configured to generate, based on the selected sound and the selected environment, an audio signal representative of an acoustic scene and use the audio signal to fit a cochlear implant system to a patient. Corresponding systems and methods are also disclosed.
US09592380B2 Electrical stimulation system with pulse control
An electrical stimulation system to provide pulse stimulation to an area of a living body by way of one or more electrode leads applied to the area, the area including an associated resistance element and an associated capacitance element. The system may include a pulse generating circuit having a controllable output voltage to generate constant voltage pulses to the one or more electrode leads, wherein the corresponding current signal of each constant voltage pulse includes an exponential decay to a steady state current value. The system may include a controller configured to estimate the associated resistance element of the area, determine a specified target steady state current value to be applied to the area, and control the pulse generating circuit to generate a constant voltage pulse to the one or more electrode leads at a calculated voltage level which achieves the specified target steady state current value to the area.
US09592379B2 Collecting gait information for evaluation and control of therapy
A medical device delivers a therapy to a patient. The medical device or another device may periodically determine an activity level or gait parameter of the patient, and associate each determined level or parameter with a current therapy parameter set. A value of at least one activity metric is determined for each of a plurality of therapy parameter sets based on the activity levels or parameters associated with that therapy parameter set. Whether the patient is currently experiencing or anticipated to experience gait freeze caused by their neurological disorder, such as Parkinson's disease, may also be determined. Gait freeze events may be associated with current therapy parameters and used to determine activity metric values. In some examples, the activity metric associated with certain therapy parameters may be presented to a user.
US09592378B2 Micro-reaction chamber microelectrodes especially for neural and biointerfaces
Biocompatible electrodes with smaller geometric area improve the selectivity of the neural recording and stimulation applications. A volume within the electrode back plane of a micro-reaction chamber (μRC) is used to confine and sequester an electrochemical reaction used for charge passage. The μRC electrode decreases impedance and improves charge storage capacity without altering the geometry of the active site.
US09592377B2 Implantable device for the brain
The present invention consists of an implantable device with at least one package that houses electronics that receives input data or signals, and optionally power, from an external system through at least one coil attached to the at least one package, processes the input data and delivers electrical pulses to neural tissue through at least one array of multiple electrodes that is/are attached to the at least one package. The invention, or components thereof, is/are intended to be installed in the head, or on or in the cranium or on the dura, or on or in the brain.
US09592368B2 Introducer sheath and method for using the same
A primary lumen and a secondary lumen, which is formed so as to be expandable, are formed inside a sheath main body having a deformation portion which is disposed so as to include at least a part of the outer peripheral portion of the sheath main body. The deformation portion is deformed so as to be expanded outwardly in accordance with the expansion of the secondary lumen.
US09592364B2 Catheter and method for producing the same
A catheter comprising a steering cable anchor, which is preferably disposed at the distal end of the catheter, and a steering cable. In order to obtain a reliable connection between the steering cable anchor and the steering cable, which is also suitable for use in MRI, a substantially dumbbell-shaped element is disposed between the steering cable anchor and the steering cable and connects the steering cable anchor to the steering cable.
US09592360B2 Gas concentrator with removable cartridge adsorbent beds
A portable oxygen concentrator designed for medical use where the sieve beds, adsorbers, are designed to be replaced by a patient. The concentrator is designed so that the beds are at least partially exposed to the outside of the system and can be easily released by a simple user-friendly mechanism. Replacement beds may be installed easily by patients, and all gas seals will function properly after installation.
US09592353B2 Adaptor/tubing with alarm(s)
The present invention relates to connectors for uses where an indicator/alarm must be activated if the axial force rises above a predetermined value. It can be used in applications where excessive forces on tubings/connectors are not acceptable, for example, in tubes/couplings in fluids, and in electronic/electric, optical and other systems where a strain-relief cannot be employed.
US09592351B2 Medicament delivery device
A medicament delivery device is presented having a housing configured to receive a medicament container having a delivery member and a shield, a protective cap, and wherein the protective cap comprises connecting means for connecting to the shield of the medicament container such that removal of the protective cap from the housing causes removal of the shield from the medicament container. The delivery device is characterized in that a protective cap assembly has a first disconnecting means configured to interact with corresponding second disconnecting means of the housing and of the protective cap such that activation of the first disconnecting means of the protective cap assembly causes the displacement of the protective cap relative to the housing.
US09592348B2 Assembly for a drug delivery device and drug delivery device
An assembly for a drug delivery device, and a drug delivery device, are proposed with a housing having proximal and distal ends. A dose member is displaceable proximally with respect to the housing for setting of a dose of a drug. A clutch member is displaceable proximally with respect to the housing when setting the dose. A stop member is configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, the clutch member, when in the clutch stop position, is prevented from further displacement proximally with respect to the housing, and the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member proximally with respect to the housing during setting of the dose.
US09592345B2 Arrangement and method for determining a stopper position
The invention relates to an arrangement for determining a position (x) of a stopper relative to a container in a drug delivery device, comprising an acoustic source configured to emit an acoustic signal and an acoustic sensor configured to detect an acoustic signal, a processing unit for controlling the acoustic source and processing the detected acoustic signal for determining characteristics of the acoustic signal correlated with the position (x) of the stopper. Furthermore, the invention relates to a method for determining a position (x) of a stopper relative to a container in a drug delivery device, the method comprising the steps of emitting an acoustic signal from an acoustic source, detecting an acoustic signal caused by the emitted acoustic signal by means of an acoustic sensor, and processing the detected acoustic signal for determining characteristics of the acoustic signal correlated with the position (x) of the stopper by means of a processing unit.
US09592342B2 Delivery of two or more medicaments through a single dose selection and dispense interface
An injection system for co-delivery of two medicaments (1, 2) having a drug delivery device (7) containing a primary reservoir (11) containing a first medicament (1) and having a secondary reservoir (5, 17, 30) containing a second medicament (2) where the drug delivery device (7) has only one dose setter (12) for the primary reservoir (11) and that automatically determines the dose of the second medicament (2). Both medicaments (1, 2) are delivered through a single dispense interface (3, 16, 21, 31).
US09592341B2 Arrangement for use in a drug delivery device
The present invention relates to an arrangement for use in a drug delivery device comprising a cartridge holder, the cartridge holder comprising an opening at its distal end, a needle holder and one or more intermediate elements, wherein when the needle holder is mounted to the cartridge holder and the one or more intermediate elements are arranged in the opening of the cartridge holder whereby the size of the free space within the opening is reduced. Furthermore, it relates to a drug delivery device which is comprising such an arrangement and to a method for stabilizing a septum located at the distal end of a medicament cartridge.
US09592340B2 Auto-injector having drive spring switching ground from distal to proximal ends of main body between pushing and retracting syringe needle
An auto-injector for administering a dose of a liquid medicament (M) is presented comprising an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament (M), the housing having a distal end (D) and a proximal end (P) with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the housing. The auto-injector contains a spring means capable of, upon activation, pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P), operating the syringe to supply the dose of medicament (M), and retracting the syringe with the needle into the covered position after delivering the medicament (M). There is also an activating means arranged to lock the spring means in a pressurized state prior to manual operation.
US09592338B2 Infusion site interfaces and insertion devices for infusion site interfaces
A device for inserting an infusion cannula, or sensor, into a patient is presented. The device comprises an insertion needle removable within the infusion cannula, a handle connected to the insertion needle, and a needle cover. The needle cover pivotably mounted on the handle is rotatably movable between a first position, i.e., the front of the insertion needle is in the needle cover, and a second position, i.e., the front is exposed. An infusion site interface comprises a body mounted on a pad attached to the patient; an infusion cannula for inserting into the patient that is connected to the body; a cavity within the body fluidly connected to the cannula; and a septum that seals closed the cavity. The septum is penetrable by an insertion needle in the infusion cannula and by a hollow needle of an infusion tubing connector coupled to the infusion site interface.
US09592337B2 Device for at least one of injection or aspiration
Micro-volume devices, systems, and associated methods that facilitate the injection or aspiration of precisely controlled volumes of materials at precisely controlled rates are provided. In one embodiment, a micro-volume device includes a syringe and a lead screw connected to a plunger of the syringe. A mechanical interface is connected to the lead screw and includes a first set of cams adjacent a proximal portion and a second set of cams adjacent a distal portion. A mechanism is configured to oscillate a structure in a direction parallel to a longitudinal axis of the lead screw such that one or more projections of the structure to alternatively engage cams of the first and second sets of cams in a manner that results in rotation of the mechanical interface in a single direction for highly controlled linear displacement of the plunger.
US09592333B2 Suction device
A suction device includes an outer tube having an inlet at a first end and an inner suction tube located within the outer tube, the inner suction tube having an inlet at a first end corresponding to the first end of the outer tube. The inlet of the inner suction tube is offset by a distance from the inlet of the outer suction tube, such that the inlet of the inner suction tube is located within the outer suction tube.
US09592332B2 Method of removing blood from an extracorporeal blood circuit, treatment apparatus, and tube system
The present invention relates to a method of removing blood from an extracorporeal blood circuit following termination of a blood treatment session, wherein blood is concurrently removed both from an arterial conduit portion and from a venous conduit portion of the extracorporeal blood circuit. It further relates to a method for recognizing and/or eliminating air inclusions in or from an extracorporeal blood circuit and a treatment apparatus as well as a tube system.
US09592330B2 Dialysis apparatus
A dialysis apparatus has a dialysate circuit 4 which is cleaned after dialysis by both opening/closing valves V101 and V102 being closed after a dialysate in the dialysate circuit 4 is replaced with a cleaning liquid. The opening/closing valve V12 is opened, and the cleaning liquid is circulated by pumps P1 and P4 while being heated by a heater H1, to clean the inside of the dialysate circuit 4. A deaeration tank 31 is provided downstream of the pump P1. Air bubbles generated from the cleaning liquid serving as hot water are deaerated by the deaeration tank 31 and are then discharged into a gas storage tank 48 via a deaeration passage 32. The pumps P1 and P4 can be reliably prevented from being unable to operate with the air bubbles generated from the cleaning liquid.
US09592328B2 Skin interface device for cardiac assist device
A skin interface device (“SID”) for a cardiac assist device, including a SID cap having a first housing, an annular sleeve, and a first annular winding disposed over said annular sleeve. The SID further includes a SID base having a second housing formed to include a tubular portion, a cylindrical member disposed in said tubular portion, and a second annular winding disposed around said cylindrical member. The SID cap is configured to be rotationally attached to said SID base. When the SID cap is attached to the SID base, the second annular winding is disposed within the first annular winding, and the relative positions of the first annular winding and the second annular winding are fixed both laterally and vertically.
US09592325B2 Polymeric, degradable drug-eluting stents and coatings
Absorbable stents and absorbable stent coatings have been developed with improved properties. These devices preferably comprise biocompatible copolymers or homopolymers of 4-hydroxybutyrate, and optionally poly-L-lactic acid and other absorbable polymers and additives. Compositions of these materials can be used to make absorbable stents that provide advantageous radial strengths, resistance to recoil and creep, can be plastically expanded on a balloon catheter, and can be deployed rapidly in vivo. Stent coatings derived from these materials provide biocompatible, uniform coatings that are ductile, and can be expanded without the coating cracking and/or delaminating and can be used as a coating matrix for drug incorporation.
US09592318B2 Topical analgesic composition
This invention concerns a synergistic combination of a topical anesthetic and wound barrier forming agent capable of providing extended analgesia of ‘significant open wounds’ (that being, for example, a laceration, surgical incision, abrasion, ulcer or burn, but not being a minor cut, scratch, sting, burn or abrasion) in which conventional management alternatives (such as suturing and/or administration of injected or systemic analgesia) are impractical, unaffordable or otherwise unavailable.
US09592307B2 Compound and photoacoustic imaging contrast medium containing the compound
The present invention provides a compound which exhibits a high degree of accumulation into a tumor even when some extent of time has passed after performing administration and which facilitates an increase in the intensity of photoacoustic signal produced by the tumor.A compound produced by bonding of a polyethylene glycol and a specific cyanine based compound.
US09592299B2 Hydrogel compositions
Fragmented polysaccharide based hydrogel compositions and methods of making and using the same are provided. The subject polysaccharide based hydrogel compositions are prepared by combining a polysaccharide component with a hydrophilic polymer and a cross-linking agent. Also provided are kits and systems for use in preparing the subject compositions.
US09592297B2 Antibody and protein formulations
Provided are salt-free antibody and other protein formulations that are substantially isosmotic and of low viscosity. Also provided are methods for the treatment of diseases using the disclosed formulations.
US09592291B2 Methods for iontophoretically treating nausea and migraine
Methods for treating nausea and migraine by iontophoretically administering triptan compounds are provided.
US09592285B2 Vaccines against multiple subtypes of influenza virus
An aspect of the present invention is directed towards DNA plasmid vaccines capable of generating in a mammal an immune response against a plurality of influenza virus subtypes, comprising a DNA plasmid and a pharmaceutically acceptable excipient. The DNA plasmid is capable of expressing a consensus influenza antigen in a cell of the mammal in a quantity effective to elicit an immune response in the mammal, wherein the consensus influenza antigen comprises consensus hemagglutinin (HA), neuraminidase (NA), matrix protein, nucleoprotein, M2 ectodomain-nucleo-protein (M2e-NP), or a combination thereof. Preferably the consensus influenza antigen comprises HA, NA, M2e-NP, or a combination thereof. The DNA plasmid comprises a promoter operably linked to a coding sequence that encodes the consensus influenza antigen. Additionally, an aspect of the present invention includes methods of eliciting an immune response against a plurality of influenza virus subtypes in a mammal using the DNA plasmid vaccines provided.
US09592284B2 Immunization regimen with E4-deleted adenovirus prime and E1-deleted adenovirus boost
An immunization regimen is provided which involves priming with an E1, E4-deleted adenovirus and boosting with an E1-deleted adenovirus. The second administered adenovirus has a capsid of a serotype which is not cross-reactive with the previously administered adenovirus. Further, a product containing the adenoviruses necessary to perform the immunization regimen is provided.
US09592276B2 Methods for treating neurological conditions and compositions and materials therefor
The present invention generally relates to methods, compositions and materials for treatment of and promotion of neurological functional recovery from neurological conditions including central nervous system injuries and/or diseases.
US09592273B2 Treatment of short bowel syndrome patients with colon-in-continuity
Intestinal absorption is enhanced in short bowel syndrome patients presenting with colon-in-continuity by treatment with a GLP-2 receptor agonist, such as teduglutide.
US09592271B2 Angiopoietin-based interventions for treating cerebral malaria
The present invention provides methods for treating, preventing or reducing the severity of cerebral malaria. The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising a modified angiopoietin molecule such as AngF1-Fc-F1.
US09592269B2 Compounds and methods of modulating angiogenesis
A pharmaceutical composition includes a synthetic peptide consisting of about 10 to about 50 amino acids and having an amino acid sequence substantially homologous to consecutive amino acids of a portion of the cytoplasmic domain of at least one of αvβ3 integrin or VEGFR2 that includes a tyrosine residue, the amino acid sequence of the peptide including a phosphorylated tyrosine residue or a γ-carboxyglutamic acid residue that is substituted for a corresponding tyrosine residue of the portion of the cytoplasmic domain of αvβ3 integrin or VEGFR2.
US09592268B2 Endothelium protective materials and methods of use
Apolipoprotein M forms a complex with sphingosine-1-phosphate (S1P) and is the carrier of S1P in high density lipoprotein particles and mediates its endothelial protective effect. Increasing the concentration of the apoM/S1P complex by administering it, either alone or in HDL particles, can prevent or treat diseases caused by endothelial cell injury, including inflammatory diseases, sepsis, atherosclerosis and acute lung injury, ischemic heart disease, stroke, vital organ failure after ischemic stress.
US09592267B2 Use of IL-18BP for treatment of peripheral vascular diseases
The invention relates to the use of an inhibitor of IL-18 in the preparation of a medicament for treatment and/or prevention of peripheral vascular diseases. The invention further relates to the use of an IL-18 inhibitor for prevention of limb amputation.
US09592261B2 Compartment-specific plant extract combination of ginkgo biloba extract and ginseng extract having a tandem effect
The invention relates to a plant extract combination of ginkgo and ginseng which is effective especially in a (synergistic) over-additive manner and optionally comprises whitethorn extract. Ginseng is used in the form of an ethanol/ethanol/water extract while ginkgo is used in the form of an acetone/acetone-water extract, for example, and the active extracts are prepared at specific quantitative ratios, particularly <1.1:1, thus unexpectedly boosting the prevention or also the treatment of a decline in the mental capacity related to age or also other disorders. This results from an over-additive tandem effect by protecting neural cells and improving blood circulation while increasing energy supply and activating cerebral metabolism, not only in the cognitive-therapeutic field, an effect being obtained against harmful oxidative influences caused especially by decomposition products of effective substances, whereby in particular antioxidative protection extends in a complementary manner to several cell compartments.
US09592259B2 APC-mediated tolerance induction for therapy of multiple sclerosis
The invention relates to transgene expression constructs—particularly self inactivating lentiviral vectors—comprising a dendritic cell specific promoter controlling the expression of autoantigen proteins, namely myelin basic protein, proteolipid protein and myelin oligodendrocyte glycoprotein, for use in the therapy of multiple sclerosis.
US09592258B2 Treatment of neurological injury by administration of human umbilical cord tissue-derived cells
Methods, pharmaceutical compositions and kits for regenerating or repairing neural tissue, decreasing apoptosis and improving neurological function following injury using human umbilical cord tissue-derived cells are disclosed.
US09592257B2 Complete human skin organ generated from culture-expanded cells
Systems and methods can support generation of a full-thickness, human skin organ from tissue culture expanded cells. Human dermal and epidermal progenitor cells can be isolated from human tissues. Isolated cells may be cultured as epidermal cells while other isolated cells may be separately cultured as dermal cells. The cultured epidermal cells and dermal cells may be combined for co-culturing. The co-cultured cells may be suspended within a slurry. The co-cultured cells may be implanted onto a recipient organism for generation of a full-thickness skin organ comprising fully cycling hair follicles, adipose tissue, and other skin organ structures.
US09592254B2 Methods for localized modification of tissue products
Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating select portions of a tissue matrix with a cross-linking agent and/or a proteolytic enzyme to produce a tissue matrix with variable mechanical and/or biological properties.
US09592251B2 Multi-vinylsulfone containing molecule
A multi-vinylsulfone containing molecule is described herein. The multi-vinylsulfone containing molecule can be formed by dissolving a water soluble polymer containing a hydroxyl group in an aqueous solution to form a polymer solution; adding a molecule containing two vinylsulfone groups to the polymer solution; and forming a modified polymer by controlling a number of the vinylsulfone groups that are added to the polymer. A hydrogel is also described herein that can include the multi-vinylsulfone containing molecule and a multi-thiol containing molecule. The hydrogel can be formed from an aqueous solution that includes the multi-vinylsulfone containing molecule and the multi-thiol containing molecule by undergoing gelatation upon delivery to a site in the body. Also described is a drug delivery system that employs the hydrogel.
US09592249B2 Compositions comprising at least one aqueous phase and at least one fatty phase which comprises avermectin compounds
Pharmaceutical/dermatological emulsions containing at least one avermectin compound, notably ivermectin, include at least one fatty phase and at least one aqueous phase, the at least one avermectin compound being solubilized in the fatty phase, which emulsions are useful for the treatment of a variety of dermatological conditions/afflictions, in particular rosacea.
US09592247B2 Method of reducing titers of antibodies specific for a therapeutic agent
The present invention relates, in general, to a method of treating patients undergoing enzyme replacement therapy (ERT) or other therapy involving the administration of a proteinaceous therapeutic agent as well gene replacement therapy with non-viral or viral vectors, or other therapeutic modality or modalities, used alone or in combination, which involve the administration of exogenous substances for potential therapeutic benefit, including, but not limited to DNA vaccines, siRNA, splice-site switching oligomers (SSOs) as well as RNA-based nanoparticles (RNPs) and nanovaccines. The invention further relates to compounds and compositions suitable for use in such methods.
US09592245B2 Very low-dosed solid oral dosage forms for HRT
The present invention relates to a very low-dosed dosage form for hormone replacement therapy (HRT). More particularly, the present invention concerns a solid oral dosage form comprising about 0.5 mg estradiol and about 0.25 mg drospirenone, and at least one pharmaceutically acceptable excipient. Despite the very low E2 and DRSP doses it has surprisingly been found that a high proportion of the women suffering from moderate to severe hot flushes actually respond to this treatment. Accordingly, the dosage form of the invention may be used as maintenance HRT or may be used already when HRT is initiated.
US09592243B2 Medical devices and methods comprising an anabolic agent for treatment of an injury
Improved medical devices and methods are provided comprising an anabolic agent for healing an injury. These improved medical devices and methods can enhance healing in injuries from traumatic soft tissue injury, surgical injuries, burn, traumatic brain injuries, musculotendinous injuries, musculoskeletal conditions, bone injury or other injuries or maladies, which can be chronic or non-chronic in origin. In some embodiments, the medical device comprises a drug depot that releases the anabolic agent over at least 2 days to enhance healing of an injury.
US09592242B2 Methods for treating edema in the eye and intraocular implants for use therefor
Methods for reducing or preventing transplant rejection in the eye of an individual are described, comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer.
US09592241B2 Silicone-based composition for skin treatment
The present embodiments may relate to topically delivered compounded medications for the treatment of scar tissue, skin disorders, and/or other ailments. In one aspect, a transdermal cream or gel may provide for the effective administration of multiple medications simultaneously. Preferably, a silicone-based gel may be provided as a base composition and may have a non-zero percentage of silicone or silicone variant. The silicone-based gel may comprise cyclopentasiloxane, polysilicone-11, dimethicone, and C30-45 alkyl cetearyl dimethicone crosspolymer, and include several active ingredients, such as glucocorticoids, antihistamines, and nerve depressants. The silicone-based gel may include a combination of fluticasone, loratadine, and gabapentin. The concentrations of fluticasone and loratadine may be relatively low, while that of gabapentin moderately high. The silicone-based gel may also have one or more local anesthetics, such as prilocaine and/or lidocaine. The silicone-based gel may include additional active ingredients, such as NSAIDs, anticonvulsants, antidepressants, muscle relaxants, and/or other active ingredients.
US09592240B2 Targeted pyrrolobenzodiazapine conjugates
Provided are Conjugate comprising PBDs conjugated to a targeting agent and methods of using such PBDs.
US09592237B2 Use of CB1 antagonists and/or inverse agonists for the preparation of drugs that increase motor neuron excitability
Use of a CB1 receptor antagonist and/or inverse agonist, preferably rimonabant, for the preparation of drugs useful for increasing motor neuron excitability in the cerebral cortex and/or in the brain stem and/or at the spinal level, as well as a method for increasing motor neuron excitability through the administration of a CB1 antagonist/ inverse agonist receptors, and to the use of a pharmaceutical composition which comprises a CB1 receptor antagonist and/or inverse agonist, preferably rimonabant, for increasing motor neuron excitability in the cerebral cortex and/or in the brain stem and/or at the spinal level.
US09592236B2 Methods of treating hemoglobinopathies
Methods of alleviating the symptoms of hemoglobinopathies, including, but not limited to, sickle cell disease, β-thalassemia, and hemoglobin H disease are provided. In some embodiments, the methods comprise administering an inhibitor selected from an ERK inhibitor, a MEK inhibitor, and a Raf inhibitor. Methods of inhibiting adhesion of sickle red blood cells to endothelial cells are also provided.
US09592234B2 Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration using isothiazolopyrimidinones
The present invention provides methods and compositions comprising compounds useful for stimulating neurogenesis. The methods and compositions comprising compounds are also useful for inhibiting neuronal degeneration. Thus, the present invention can be used in the treatment of diseases and conditions characterized by neuronal loss and reduced neurogenesis including Alzheimer's disease, stroke, traumatic brain injury, traumatic nerve injury, and depression. This invention is useful for research products including single agents or mixtures of agents to promote, proliferate, differentiate, or maintain neurons from stem or progenitor cells.
US09592231B2 Therapy for complications of diabetes
A method for enhancing glycemic control and/or insulin sensitivity in a human subject having diabetic nephropathy and/or metabolic syndrome comprises administering to the subject a selective endothelia A (ETA) receptor antagonist in a glycemic control and/or insulin sensitivity enhancing effective amount. A method for treating a complex of comorbidities in an elderly diabetic human subject comprises administering to the subject a selective ETA receptor antagonist in combination or as adjunctive therapy with at least one additional agent that is (i) other than a selective ETA receptor antagonist and (ii) effective in treatment of diabetes and/or at least one of said comorbidities other than hypertension. A therapeutic combination useful in such a method comprises a selective ETA receptor antagonist and at least one antidiabetic, anti-obesity or antidyslipidemic agent other than a selective ETA receptor antagonist.
US09592228B2 Treatment of inflammation using alpha 7 receptor-binding agonists
Methods of inhibiting release of a proinflammatory cytokine from a macrophage are provided. The methods comprise treating the macrophage with a cholinergic agonist in an amount sufficient to decrease the amount of the proinflammatory cytokine that is released from the macrophage, wherein the cholinergic agonist is selective for an α7 nicotinic receptor. Methods for inhibiting an inflammatory cytokine cascade in a patient are also provided. The methods comprise treating the patient with a cholinergic agonist in an amount sufficient to inhibit the inflammatory cytokine cascade, wherein the cholinergic agonist is selective for an α7 nicotinic receptor. Methods for determining whether a compound is a cholinergic agonist reactive with an α7 nicotinic receptor are also provided. The methods comprise determining whether the compound inhibits release of a proinflammatory cytokine from a mammalian cell. Additionally, methods for determining whether a compound is a cholinergic antagonist reactive with an α7 nicotinic receptor are provided. These methods comprise determining whether the compound reduces the ability of a cholinergic agonist to inhibit the release of a proinflammatory cytokine from a mammalian cell. Oligonucleotides or mimetics capable of inhibiting attenuation of lipopolysaccharide-induced TNF release from a mammalian macrophage upon exposure of the macrophage to a cholinergic agonist are also provided. The oligonucleotides or mimetics consist essentially of a sequence greater than 5 nucleotides long that is complementary to an mRNA of an α7 receptor. Additionally, methods of inhibiting attenuation of TNF release from a mammalian macrophage upon exposure of the macrophage to a cholinergic agonist are provided. These methods comprise treating the macrophage with the above-described oligonucleotide or mimetic.
US09592227B2 Compositions of a polyorthoester and an aprotic solvent
Delivery systems and compositions comprised of a biodegradable polyorthoester polymer, an aprotic solvent, and a drug are described. The solvent is selected to modulate release of drug from the composition, where, in some embodiments, the solvent is rapidly released after administration and provides a corresponding rapid rate of drug release. Alternatively, in other embodiments, the solvent is slowly released from the composition after its administration, and provides a correspondingly slow rate of drug release.
US09592225B2 Crystalline N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mono mesylate monohydrate having a specific particle size distribution range and a specific surface area range for use in pharmaceutical formulations
The present invention relates to the crystalline mono mesylate monohydrate salt of N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide in a definite particle size range, particle size distribution and a specific surface area range, which has demonstrated increased long term stability and release kinetics from pharmaceutical compositions, as well as to pharmaceutical compositions containing said crystalline N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mono mesylate monohydrate having the afore-mentioned particle size range, particle size distribution and specific surface area range. Moreover, the present invention relates to the pharmacokinetic and pharmacodynamic in vivo profiles of the resultant free base of N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]-acetamide after administration of the afore-mentioned crystalline N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]-acetamide mono mesylate monohydrate salt to a subject in need thereof.
US09592223B2 Small molecule inhibitors of MALT1
MALT1 cleavage activity is linked to the pathogenesis of activated B-cell-like diffuse large B-cell lymphoma (ABC-DLBCL), a chemo-resistant form of DLBCL. We developed a MALT1 activity assay and identified chemically diverse MALT1 inhibitors. A selected lead compound MI-2 featured direct binding to MALT1 and suppression of its protease function. MI-2 concentrated within human ABC-DLBCL cells and irreversibly inhibited cleavage of MALT1 substrates. This was accompanied by suppression of NF-KB reporter activity, inhibition of nuclear localization of c-REL and downregulation of NF-KB target gene signature. Most notably, MI-2 was non-toxic to mice, and displayed potent and specific activity against ABC-DLBCL cell lines in vitro, and xenotransplanted ABC-DLBCL tumors in vivo. The compound was also effective against primary human non-GCB-DLBCLs ex vivo.
US09592214B2 Compounds for the treatment of autism in a baby child
The invention relates to a compound which inhibits the importation of chloride into neurons or a compound which improve the outflow of chloride from neurons for use in the treatment of autism in a baby or a fetus in need thereof.
US09592208B2 Formulations comprising 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol
A solid pharmaceutical composition suitable for oral administration, comprising: (a) a S1P receptor modulator; (b) a filler, and (c) a cyclodextrin.
US09592207B2 Intranasal administration of ketamine to treat depression
Methods and compositions for the treatment of treatment-resistant depression are described. More specifically, the invention demonstrates that intranasal administration of ketamine is effective to ameliorate the symptoms of depression in a patient who has not responded to an adequate trial of one antidepressant in the current episode and has recurrent or chronic depressive symptoms (>2 years).
US09592206B2 Methods of using water-soluble inorganic compounds for implants
A method for controlling generation of biologically desirable voids in a composition placed in proximity to bone or other tissue in a patient by selecting at least one water-soluble inorganic material having a desired particle size and solubility, and mixing the water-soluble inorganic material with at least one poorly-water-soluble or biodegradable matrix material. The matrix material, after it is mixed with the water-soluble inorganic material, is placed into the patient in proximity to tissue so that the water-soluble inorganic material dissolves at a predetermined rate to generate biologically desirable voids in the matrix material into which bone or other tissue can then grow.
US09592199B2 Cellulose powder
This cellulose powder has: an average degree of polymerization of 100 to 350; a weight average particle size of over 30 μm, but less than 250 μm; an apparent specific volume of 2 to less than 15 cm3/g; and a particle size distribution sharpness of 1.5 to 2.9.
US09592198B2 Microfluidic liposome synthesis, purification and active drug loading
Microfluidic methods and systems are provided for continuous flow synthesis and active loading of liposomes, which include a liposome formation region configured to form a population of liposomes and a microdialysis region downstream from the liposome formation region and configured to form a transmembrane gradient for active drug loading of the liposomes. Microfluidic methods and systems for high throughput production of liposomes are also provided featuring high aspect ratio microchannels.
US09592197B2 Dosage form containing diphenhydramine and another drug
A pharmaceutical dosage form which comprises diphenhydramine and/or a pharmaceutically acceptable salt thereof and at least one second drug. The dosage form provides a plasma concentration within the therapeutic range of the at least one second drug over a period which is coextensive with a substantial part of the period over which the dosage form provides a plasma concentration within the therapeutic range of diphenhydramine or salt thereof. This Abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.
US09592195B2 Stable effervescent bisphosphonate formulations with rapid solubilization characteristics
A stable effervescent tablet, granule or powder composition free from excipients that may react with an effervescing organic acid component, comprising, an effective amount of a bisphosphonate bone resorption inhibitor, an effervescing organic acid component, an effervescing base component; wherein said composition is free of polyol binders and tableting lubricants; has a loss on drying of 0.25% (m/m) or less; has a complete disintegration time of no more than 180 seconds when placed in 3 to 8 fluid ounces of water at between 5-20° C.; and said bisphosphonate is incorporated as a micronized particle or by spray drying and is completely solubdised in water within 2 minutes without stirring.