Document Document Title
US09441241B2 Methods and compositions for transgenic plants with enhanced resistance to biotic and abiotic stress
The present invention provides methods and compositions for producing transgenic plants having increased resistance to biotic and/or abiotic stress and comprising an exogenous nucleotide sequence encoding a cysteine protease inhibitor.
US09441239B2 Methods and means for obtaining modified phenotypes
Methods and means are provided for reducing the phenotypic expression of a nucleic acid of interest in eucaryotic cells, particularly in plant cells, by introducing chimeric genes encoding sense and antisense RNA molecules directed towards the target nucleic acid, which are capable of forming a double stranded RNA region by base-pairing between the regions with sense and antisense nucleotide sequence or by introducing the RNA molecules themselves. Preferably, the RNA molecules comprises simultaneously both sense and antisense nucleotide sequence.
US09441236B2 Transgenic bioluminescent plants
Transgenic plants, and a method for making the same, wherein genes encoding the enzyme luciferase and its corresponding substrate luciferin are incorporated into a native plant genome. Once transformed into plant cells, these genes may be regulated such that under certain endogenous or exogenous conditions, their expression in the mature plant results in bioluminescence. Different luciferin/luciferase complexes and/or mechanisms of regulation may be utilized for these transgenic plants, depending on a variety of factors such as plant species and the circumstances under which a biolmuniescent reaction is desired. Phototransformation may be utilized to vary the wavelength of light emitted from the mature plant.
US09441235B2 Feruloyl-CoA:monolignol transferase
The invention relates to nucleic acids encoding a feruloyl-CoA:monolignol transferase and the feruloyl-CoA:monolignol transferase enzyme that enables incorporation of monolignol ferulates, for example, including p-coumaryl ferulate, coniferyl ferulate, and sinapyl ferulate, into the lignin of plants.
US09441231B2 Chimeric and proline rich protein promoters for expression in plants
The present invention provides regulatory polynucleotide molecules isolated from plant proline rich protein genes and linked to a viral enhancer molecule. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds containing the regulatory polynucleotide sequences, and methods for preparing and using the same.
US09441226B2 Methods and compositions for panic disorders
Methods and compositions that down regulate the activity of orexins to treat panic disorder and panic-like responses associated with hypercapnic conditions are disclosed.
US09441225B2 Compositions and methods for inhibiting expression of factor V
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of Factor V, comprising an antisense strand having a nucleotide sequence which is less that 25 nucleotides in length and which is substantially complementary to at least a part of Factor V. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of Factor V using the pharmaceutical composition; and methods for inhibiting the expression of Factor V in a cell.
US09441224B1 Long noncoding RNAS and cell reprogramming and differentiation
Long noncoding RNAs (lncRNAs) are identified that enhance pluripotency reprogramming of somatic cells as well as differentiation of pluripotent cells. Induced pluripotent stem (iPS) cell generation from somatic cells leads to the upregulation and downregulation of identified lncRNAs. The modulation of these lncRNAs are capable of enhancing pluripotency of somatic cells as well as enhancing differentiation of a pluripotent cell.
US09441223B2 Transposable elements, TDP-43, and neurodegenerative disorders
A method that includes measuring the expression level of at least one transposon in a biological sample from a subject; and determining whether the measured transposon expression exceeds a predetermined level, and if so, administering to the subject a transposon inhibitor in an amount effective to reduce the expression level of a transposon.
US09441218B2 Salt tolerant lucerne
A salt tolerant Medicago sativa plant designated as “Silverosa” representative seed of which having been deposited under NCIMB Accession No. 41909, NCIMB Accession No. 41910 and NCIMB Accession No. 41911.
US09441214B2 Polypeptide having beta-glucosidase activity and uses thereof
The invention relates to a polypeptide comprising the amino acid sequence set out in SEQ ID NO: 2 or an amino acid sequence encoded by the nucleotide sequence of SEQ ID NO: 1, or a variant polypeptide or variant polynucleotide thereof, wherein the variant polypeptide has at least 96% sequence identity with the sequence set out in SEQ ID NO: 2 or the variant polynucleotide encodes a polypeptide that has at least 96% sequence identity with the sequence set out in SEQ ID NO: 2. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional polypeptide and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins.
US09441209B2 Down-regulation of a polynucleotide encoding a Sou2 sorbitol utilization protein to modify lipid production in microbial cells
Recombinant microbial cells are disclosed herein that comprise (i) a down-regulation of an endogenous polynucleotide sequence encoding Sou2 sorbitol utilization protein, and (ii) a polyunsaturated fatty acid (PUFA) biosynthetic pathway. The down-regulation of the polynucleotide sequence encoding Sou2 sorbitol utilization protein can increase the lipid content of the microbial cells and/or decrease the total amount of sugar alcohols produced by the microbial cells. Also disclosed are methods of using the recombinant microbial cells to produce oil containing omega-3 polyunsaturated fatty acids such as EPA.
US09441206B2 Cell line for production of adeno-associated virus
This invention relates to a HEK293 cell line that grows under animal component-free suspension conditions. The cell line is ideal for rapid and scalable production of adeno-associated virus (AAV) and supports production of all serotypes and chimera of AAV.
US09441205B2 Two plasmid mammalian expression system
Reverse engineering has offered new ways of studying the pathology of RNA viral infections, new more efficient devices of synthesizing recombinant viruses and developing vaccines and also demonstrated the versatility and efficiency of RNA dependent RNA polymerase RDRP system as an expression system. However, the currently used methods require a repertoire of complex, difficult-to-use tools. Present invention describes, a simpler plasmid based mammalian expression system that uses the RDRP enzyme activity for expression of recombinant proteins or RNA from viral minigenomes and rescue of recombinant viruses from cDNAs encoding entire genome(s) of negative stranded RNA viruses. This system will be useful for expression of recombinant proteins, therapeutic RNA molecules including anti-sense and/or selecting interfering RNA and Ribozymes. This system can also be used for gene therapy and producing recombinant viruses for production of new vaccines.
US09441203B2 Medium for the protein-free and serum-free cultivation of cells
A medium is described for the protein-free and serum-free cultivation of cells, especially mammalian cells, whereby the medium contains a proportion of soy hydrolysate.
US09441202B2 Molecules with effects on cellular development and function
This invention relates to methods to stabilize and/or improve the function of parenchymal cells. Also provided are systems of co-cultures of hepatocyte-stabilizing non-parenchymal cells used in bioreactor microenvironments to identify hepatic stabilizing factors by gene-expression profiling.
US09441200B2 Compositions and methods for implantation of adipose tissue and adipose tissue products
The invention provides compositions and methods for the preparation of biocompatible biomaterials from adipose tissue. Biocompatible biomaterials are cellular or acellular biomaterials. The invention further provides methods of use of the biocompatible biomaterials.
US09441199B2 Cells exhibiting neuronal progenitor cell characteristics and methods of making them
Disclosed are cells exhibiting neuronal progenitor cell characteristics, and methods of making them from marrow adherent stem cells by regulating cellular pathways in the marrow adherent stem cells that are associated with glial transdifferentiation of the marrow adherent stem cells.
US09441194B2 Device for producing a three-dimensional structural cell
A device 2 for producing a three-dimensional structural body has an accommodating plate 3 in which an accommodating recess portion 3a for accommodating a cell mass 1 is formed, a support body 4 provided with a plurality of needle-shaped bodies 6 penetrating the cell mass, a suction nozzle 19 for adsorbing/holding the cell mass, and structure 20 for moving the suction nozzle.
US09441192B2 Cell culture methods and devices utilizing gas permeable materials
Gas permeable devices and methods are disclosed for cell culture, including cell culture devices and methods that contain medium at heights, and certain gas permeable surface area to medium volume ratios. These devices and methods allow improvements in cell culture efficiency and scale up efficiency.
US09441191B2 Omni-functional high-efficient solid-state fermentation method for edible and medicinal microorganisms
A solid-state fermentation method is provided. The method is provided for edible and medicinal microorganisms. A commensurate device is used for processing sterilization, inoculation, cultivation, drying, and collection. Cultivation substrates are filled in cultivation plates and placed on trays of a movable layer rack in a reaction fermenter for fermentation. Inner pipes provide inoculation, fluid nutrient, and air for fermentation of microorganisms. The reaction fermenter is accompanied with a dry circulation unit and a production collection unit for drying and collection. The solid-state fermentation processes are thus effectively integrated without the need of transferring fermented products between stations, which largely reduces contamination rate. Even more, there is no need to purchase automatic production equipments of high mechanical technologies. Thus, the present invention reduces labor requirement, saves time and energy, deducts cost of automatic equipments, achieves low contamination rate, and processes automatic mass production even without automatic production equipments.
US09441185B2 Perfume systems
The present application relates to perfume delivery systems and consumer products comprising perfume delivery systems and or perfume raw materials, as well as processes for making and using such perfume delivery systems and consumer products.
US09441183B1 Wash-out resistant underwater grease
A novel lubricating grease that is useful for underwater applications is made up of lubricating oil that contains a co-polymer of a hydrocarbon backbone for promoting good adhesion and a fluorine containing backbone for promoting lubricity. The grease formulation is resistant to water washout and does not off-gas toxic compounds. In addition to the lubricating oil, the grease formulation includes fumed silica, and may contain one or more corrosion inhibitors, an extreme pressure filler such as boron nitride, and optionally one or more polyurethane initiators.
US09441178B2 Materials as additives for advanced lubrication
This invention relates to carbon-based materials as anti-friction and anti-wear additives for advanced lubrication purposes. The materials comprise carbon nanotubes suspended in a liquid hydrocarbon carrier. Optionally, the compositions further comprise a surfactant (e.g., to aid in dispersion of the carbon particles). Specifically, the novel lubricants have the ability to significantly lower friction and wear, which translates into improved fuel economies and longer durability of mechanical devices and engines.
US09441174B2 Multistage resid hydrocracking
Processes for upgrading resid hydrocarbon feeds are disclosed. The upgrading processes may include: hydrocracking a resid in a first reaction stage to form a first stage effluent; hydrocracking a deasphalted oil fraction in a second reaction stage to form a second stage effluent; fractionating the first stage effluent and the second stage effluent to recover at least one distillate hydrocarbon fraction and a resid hydrocarbon fraction; feeding the resid hydrocarbon fraction to a solvent deasphalting unit to provide an asphaltene fraction and the deasphalted oil fraction.
US09441173B2 Process for making diesel by oligomerization
Disclosed is that by oligomerizing C4 olefins over a uni-dimensional 10-ring pore structured zeolite catalyst, at least 70 wt % oligomers having at least 9 carbons can be produced in a single pass.
US09441170B2 Device and method for upgrading petroleum feedstocks and petroleum refinery streams using an alkali metal conductive membrane
A reactor has two chambers, namely an oil feedstock chamber and a source chamber. An ion separator separates the oil feedstock chamber from the source chamber, wherein the ion separator allows alkali metal ions to pass from the source chamber, through the ion separator, and into the oil feedstock chamber. A cathode is at least partially housed within the oil feedstock chamber and an anode is at least partially housed within the source chamber. A quantity of an oil feedstock is within the oil feedstock chamber, the oil feedstock comprising at least one carbon atom and a heteroatom and/or one or more heavy metals, the oil feedstock further comprising naphthenic acid. When the alkali metal ion enters the oil feedstock chamber, the alkali metal reacts with the heteroatom, the heavy metals and/or the naphthenic acid, wherein the reaction with the alkali metal forms inorganic products.
US09441167B2 Boron oxide in FCC processes
Fluid catalytic cracking (FCC) processes are described, the processes utilizing one or more boron oxide components. Also described are FCC compositions and methods of manufacture. One or more boron oxide components on FCC compatible inorganic particles are added to a FCC unit to crack hydrocarbon feeds, resulting in lower hydrogen and coke yields.
US09441159B2 Method for producing composition
A raw material composition containing a hindered phenol compound having a specified structure and a compound constituting a liquid crystal material is prepared, the raw material composition is brought into contact with a purifying agent after being dissolved in an organic solvent or without the addition of an organic solvent to the raw material composition, and then the purifying agent is removed, and when a composition after the purifying agent is removed does not contain the organic solvent, the composition is provided as a target composition, and when the composition after the purifying agent is removed contains the organic solvent, the organic solvent is distilled off to provide a target composition.
US09441151B2 Wellbore servicing materials and methods of making and using same
A method of servicing a wellbore in a subterranean formation comprising placing a wellbore servicing fluid in the wellbore and/or subterranean formation, wherein the wellbore servicing fluid comprises a hydrophobically modified relative permeability modifier, an oxygenated alkylating agent, and an aqueous base fluid, and allowing the wellbore servicing fluid to modify the permeability of at least a portion of the wellbore and/or subterranean formation.
US09441147B2 Hybrid cement set-on-command compositions
The present invention relates to methods and compositions useful for isolating a portion of a wellbore. In one embodiment, a method includes preparing a sealant composition containing two phases. The sealant composition is placed into the wellbore where one phase sets upon subjecting the sealant composition to a thermal source followed by the setting of the other phase.
US09441142B2 Hydrophilic adhesives and tapes and devices containing the same
Hydrophilic adhesive compositions are disclosed that contain a surfactant that is miscible, but not fully soluble in the polymer matrix of the adhesive. This permits the surfactant to continuously replenish at the surface of the adhesive as other surfactant is removed, such as when it is carried away by an aqueous sample flowing over that surface in an in-vitro diagnostic device, resulting in adhesive compositions that are inherently hydrophilic on their surfaces and do not rely on the bloom mechanism of known hydrophilic adhesives. This provides greater design options for in-vitro diagnostic device manufacturers, including the use of hydrophilic adhesive spacers in lieu of or in combination with hydrophilic top covers.
US09441132B2 Methods for preparing highly viscous ionomer-poly(vinylalcohol) coatings
Disclosed are methods to form coatings on a substrate, the coatings comprising a blend of a poly(vinyl alcohol) composition comprising a poly(vinyl alcohol) characterized by a hydrolysis level of from about 85 to about 93 mole % and a 4 weight % aqueous viscosity at 20° C. of about 16 to about 75 centipoise; and an ionomer comprising a parent acid copolymer that comprises ethylene and about 18 to about 30 weight % of acrylic acid or methacrylic acid, the acid copolymer having a melt flow rate from about 200 to about 1000 g/10 min., wherein about 50% to about 70% of the carboxylic acid groups of the copolymer are neutralized to carboxylic acid salts comprising potassium cations, sodium cations or combinations thereof. Multilayer structures comprising the blend composition on a substrate are also disclosed.
US09441131B2 CNT/fluoropolymer coating composition
Exemplary embodiments provide nanotube-containing coating compositions and methods for making and using the coating compositions. In an exemplary embodiment, the coating composition can include a plurality of nanotubes (e.g., carbon nanotubes (CNTs)) dispersed stably and uniformly in a polymer matrix containing fluoropolymers. The coating composition can further include stabilizers to allow a stable and/or uniform dispersion of the plurality of nanotubes in the fluoropolymers. The nanotube coating composition can be coated on an article surface to improve mechanical robustness, and electrical and thermal conductivity of the coated article. The coated article can be used as, for example, a fuser member, a fixing member, a pressure roller, or a release agent donor member in an electrostatographic printing machine or process.
US09441130B2 Easily dispersible formulations of pigments and their use in tinting base media
Formulations of easily dispersible (ED) pigments comprising a combination of a carboxylic acid polymer and a non-ionic alkoxylated surfactant are disclosed. The combination is used in the formulation of a plurality of pigments. The formulations are suitable for mixing with a base medium at the point-of-sale (PoS) or by the end user.
US09441129B2 Ink for inkjet recording, ink container, and inkjet recording device
An ink for inkjet recording contains water, an organic solvent, a pigment, and a compound represented by the following Chemical formula 1: In Chemical formula 1, M+'s each, independently represent protons, cations of alkali metals, ammonium ions, or organic ammonium ions.
US09441125B2 Photo-curable ink composition
A photo-curable ink composition including UV curable polyurethane dispersions, water, photo-initiator, colorant and hydrophobic radiation-curable monomers. Also disclosed herein is a method for forming a printed article and an inkjet printing system using said photo-curable ink composition.
US09441118B2 Water soluble polymer powders with improved dispersibility
The presently disclosed and claimed inventive concept(s) relates to a dry powder composition comprising water soluble polymer powders, and a component in powder form. The dry powder composition shows improved water dispersibility compared to the water soluble polymer powders. The presently disclosed and claimed inventive concept(s) further relates to an aqueous protective coating composition comprising the dry powder composition.
US09441117B2 Mixtures, methods and compositions pertaining to conductive materials
This invention pertains to mixtures and methods that can be used to produce materials comprising an electrically and/or thermally conductive coating as well as compositions that are materials that possess an electrically and/or thermally conductive coating. The mixtures and methods can be used to fabricate transparent conductive films and other transparent conductive materials.
US09441115B2 Aqueous phase pore sealing agent imroving PCB coating oxidation-resistant and corrosion-resistant properties and method for using same
The present invention relates to a water-based pore sealing agent enhancing PCB coating anti-oxidation and anti-corrosion properties, consisting of, by weight, 4-12 parts of a corrosion inhibitor, 15-25 parts of a mixed surfactants system, 10-20 parts of an ion chelating agent, 6-15 parts of a pH regulator, 20-40 parts of a builder, and the rest being purified water. When used to perform pore sealing on a PCB, the water-based pore sealing agent is diluted with purified water first to be diluted 10-100 times, preferably, 100/8-100/3 times. The pH value is 7-11, and is preferably 7.5-9.5. The surface tension is 18-28 dyn/cm. The pore sealing treatment uses a immersion process, and preferably ultrasonic waves are added at the same time to assist in cleaning the pores. For the pore sealing treatment, the temperature is 20-60° C., and the time is 60-150 seconds. After pore sealing, the temperature for drying the coated piece is 80-150° C., and the time is 60-120 seconds. The PCB treated with the water-based pore sealing agent of the present invention undergoes the neutral salt spray test, the nitric acid vapor test, the mixed gas test, and the sulfur dioxide and bonding tensile strength test, and the results have indicated that the anti-oxidation and anti-corrosion properties of the coating thereof are significantly enhanced.
US09441114B2 High temperature bond coating with increased oxidation resistance
A bond coating having high corrosion and oxidation resistance and good compatibility with a thermal barrier coating is disclosed. The bond coating may be an optimized NiCrAlY material with additional materials that eliminates the presence of beta phase for oxidation by replacing the beta phase with a gamma/gamma prime system. The bond coating may also decrease the presence of phases that are detrimental to the mechanical and oxidation properties of the system, such as the sigma and BCC chromium phases. The bond coating may also have a gamma/gamma prime transition temperature that is about 400 degrees Celsius higher than conventional bond coatings, which enables local stresses to be reduced.
US09441108B2 Thermoset polyurethane foam containing brominated polymeric flame retardant
Prepare a thermoset polyurethane foam containing a brominated polymer with aliphatic bromine as a flame retardant.
US09441105B2 Biodegradable resin composition, and biodegradable film
There are disclosed a biodegradable resin composition including a starch (a1), a biodegradable resin (a2) other than a polylactic acid-based polymer and a non-crystalline polylactic acid-based polymer (b), a mass ratio of the starch (a1) to the biodegradable resin (a2) other than a polylactic acid-based polymer (a1/a2) being from 20/80 to 50/50, and a mass ratio of a sum of the components other than the polymer (b) to the polymer (b) (sum of components other than polymer (b)/polymer (b)) being from 95/5 to 50/50, and a biodegradable film using the biodegradable resin composition.
US09441101B2 Fluororubber composition
Provided is a fluororubber composition which does not deteriorate workability during roll kneading, does not cause foaming during crosslinking and molding, and is capable of giving a crosslinked molded article which exhibits desired hardness and sealing property without using a reinforcing inorganic filler such as carbon black and silica. The fluororubber composition includes, relative to 100 parts by weight of a vinylidene fluoride-copolymerized, fluorine-containing elastomer copolymer having a glass transition temperature and a melting point, no reinforcing inorganic filler, 5 to 100 parts by weight of a PTFE filler, 0.5 to 10 parts by weight of a polyol crosslinking agent, 1 to 15 parts by weight of magnesium oxide, and 0.1 to 2 parts by weight of hydrotalcite. Preferably, 0.1 to 10 parts by weight of a quaternary onium salt crosslinking accelerator is further included.
US09441097B2 Rubber composition and tire produced by using the same
A rubber composition containing 100 parts by mass of a rubber component (A) comprising at least one rubber of natural rubber and synthetic diene base rubbers and 5 to 120 parts by mass of a low molecular weight aromatic vinyl compound-diene compound copolymer (B) having a weight average molecular weight (measured by gel permeation chromatography and reduced to polystyrene) of 1,000 to 300,000 and, wherein the copolymer (B) comprises 0 to 80% by mass of an aromatic vinyl compound and has a vinyl bond content of 0 to 80% by mass in the part of the diene compound, and has a cross-linkable functional group at an end. Further, tires produced by using the rubber composition are provided.
US09441093B2 Acrylic rubber composition, and crosslinked product thereof
Provided is an acrylic rubber composition having further improved compression set resistance and comprising, based on 100 parts by mass of (a1) an acrylic rubber obtained by copolymerizing 0.1 to 10% by mass of a crosslinkable group-containing monomer, (a2) 0.4 to 50.0% by mass of a liquid fluororubber, and the crosslinked product thereof.
US09441086B2 Curable silicone compositions, electrically conductive silicone adhesives, methods of making and using same, and electrical devices containing same
A curable silicone composition containing a curable organosiloxane composition, silver, and at least one electrically conductive metal other than silver, the curable silicone composition being characterizable by a total silver concentration of from 50 to less than 60 weight percent and a thixotropic index that is adjustable from 3 to 10 measured according to TI Test Method while the composition remains curable to an electrically conductive silicone adhesive having a volume resistivity of less than 0.001 Ohm-centimeter measured according to Volume Resistivity Test Method without increasing the total concentration of electrically conductive metal in the curable silicone composition to 72 weight percent or higher, the electrically conductive silicone adhesive, an electrical device comprising the electrically conductive silicone adhesive, and a method of manufacturing the electrical device.
US09441085B2 Polyamides compositions featuring improved thermal stability
The present invention relates to polyamide compositions featuring improved thermal stability comprising at least one semi-aromatic polyamide, PA 6 and/or PA 6,6, and elemental iron. These new compositions are very well suited for the manufacture of articles exposed to high temperature environments such as articles used in automotive applications.
US09441082B2 Polyimide film and process for producing the same
A process includes the steps of: casting or coating a polyamic acid organic solvent solution on a support and drying the polyamic acid organic solvent solution thereon, so as to form a partially cured and/or partially dried polyamic acid film; dipping the polyamic acid film in tertiary amine or a solution of tertiary amine, or coating tertiary amine or a solution of tertiary amine on the polyamic acid film; and drying the film while imidizing the polyamic acid. In another process, a chemical converting agent and a catalyst are mixed in an organic solvent solution of polyamic acid. After casting and heating the mixture on a support, a partially cured and/or partially dried polyamic acid film is detached from the support. The film contains, with respect to the remaining volatile component, not less than 50 parts of catalyst, not more than 30 parts of solvent, and not more than 20 parts of chemical converting agent and/or a chemical converting agent derived component. The remaining amic acid is imidized and the film is dried.
US09441079B2 Block copolymer comprising polyorganosiloxane block and polyolefin block
Presently described are block copolymers suitable for use as a low adhesion backsize (“LAB”) coating. The block copolymers comprise at least one polyorganosiloxane block and at least one polyolefin block. The polyolefin block is semi-crystalline having a melt point of at least 110° C. The block copolymer typically has the structure: A[-L-B]n wherein A is a polyorganosiloxane block and B is a polyolefin block. L is a covalent bond or a divalent linking group. In some embodiments, L is the reaction product of an amine or hydroxyl and an anhydride.
US09441078B2 Self-assembling polymers—I
Disclosed are self-assembling diblock copolymers of the formula (I): wherein R1-R4, n, and m are as described herein, which find use in preparing porous membranes. Embodiments of the membranes contain the diblock copolymer self-assembled into a cylindrical morphology. Also disclosed is a method of preparing such copolymers.
US09441076B2 Multifunctional graphene-silicone elastomer nanocomposite, method of making the same, and uses thereof
A nanocomposite composition having a silicone elastomer matrix having therein a filler loading of greater than 0.05 wt %, based on total nanocomposite weight, wherein the filler is functional graphene sheets (FGS) having a surface area of from 300 m2/g to 2630 m2/g; and a method for producing the nanocomposite and uses thereof.
US09441074B2 Arc-extinguishing insulation material molded product and gas circuit breaker including the same
The present invention relates to an arc-extinguishing insulation material molded product provided in the vicinity of a contact point between contactors in a gas circuit breaker. The arc-extinguishing insulation material molded product includes a polymer which contains a carbon-oxygen bond in the main chain, and in which a part of or all of terminal atoms are non-hydrogen atoms.
US09441067B2 Process for making long fiber-reinforced polyurethanes that contain particulate fillers
Fiber-reinforced polyurethane structures are made with a polyol composition that contains a particulate filler such as calcium carbonate, in addition to the fibers. The polyol composition and the polyisocyanate composition are selected such that the polymer formed in their reaction has a calculated molecular weight between crosslinks (Mc) of from 300 to 420. The polyisocyanate component contains a urethane-modified MDI and/or a urethane-modified polymeric MDI.
US09441065B2 Curable composition for imprints, cured product and method for manufacturing a cured product
Provided is a curable composition for imprints having good patternability and dry etching resistance. Disclosed is a curable composition for imprints comprising a polymerizable monomer (Ax) having a substituent having an aromatic group and having a molecular weight of 100 or more, and a photopolymerization initiator.
US09441064B2 Curable composition, transparent heat-resistant material, and use thereof
The present invention provides a curable composition, which contains a crosslinking aid (B) containing three or more allyl groups in the molecule in an amount of 1 to 50 parts by mass, polyfunctional (meth)acrylic compound (C) in an amount of 5 to 50 parts by mass, and photopolymerization initiator (D1) and/or thermal polymerization initiator (D2) in an amount of 0.1 to 10 parts by mass, respectively, as a polymerization initiator (D) to 100 parts by mass of allyl group-terminated allyl ester oligomer (A); wherein the crosslinking aid (B) containing allyl group is a compound containing three or more allyl groups in a molecule; wherein the content of impurities derived from the crosslinking aid (B) in the curable composition is less than 0.1 mass %; wherein the content of the (meth)acrylic compound containing a hydroxyl group in a molecule (C1) in the curable composition is 0.5 to 30 mass %.
US09441061B2 Polymer films having improved heat sealing properties
A polymer composition comprising an ethylene alpha-olefin copolymer, wherein the polymer composition is characterized as having (a) a density in the range of from greater than about 0.910 g/cc to about 0.930 g/cc, as determined according to ASTM D1505; (b) a melt index in the range of from greater than about 0.5 g/10 min to about 3 g/10 min, as determined by ASTM D1238, Condition 190° C./2.16 kg; (c) a molecular weight distribution of from about 3.4 to about 12, as determined by gel permeation chromatography (GPC); (d) a weight average molecular weight of from greater than about 85 kg/mol to about 160 kg/mol, as determined by gel permeation chromatography (GPC); and (e) a z-average molecular weight of from greater than about 210 kg/mol to about 500 kg/mol, as determined by gel permeation chromatography (GPC).
US09441059B2 Metathesis catalysts and methods thereof
The present application provides, among other things, compounds and methods for metathesis reactions. In some embodiments, a provided compound has the structure of formula I, II or III. In some embodiments, R1 of formula I, II or III comprises an electron-withdrawing group. In some embodiments, the present invention provides methods for preparing provided compounds.
US09441057B1 High-pressure polymerization process of ethylenically unsaturated monomers in a tubular reactor
The present technology relates to a process for polymerizing or copolymerizing ethylenically unsaturated monomers in the presence of free-radical polymerization initiators, wherein the polymerization is carried out in a continuously operated tubular reactor at temperatures from 100° C. to 350° C. and pressures from 180 MPa to 340 MPa, with a specific reactor surface area Asp of 2 m2/(t/h) to 5.5 m2/(t/h), and the tubular reactor has a specific ratio RDsp of 0.0050 MPa−1 to 0.0069 MPa−1 and an inner surface which has a surface roughness Ra of 2 μm or less.
US09441055B1 Arylcyclobutenes
Arylclobutene-containing multi-functional monomers are useful in the preparation of arylcyclobutene-based polymer coatings. Compositions comprising one or more arylclobutene-containing multi-functional monomers and one or more oligomers comprising as polymerized units one or more arylcyclobutene monomer provide arylcyclobutene-based polymer coatings having reduced stress. Such compositions are useful in the manufacture of electronic devices.
US09441054B2 Vinylidene fluoride copolymers
The present invention pertains to a fluoropolymer [polymer (F)] comprising: recurring units derived from vinylidene fluoride (VDF), and from 0.01% to 5% by moles of recurring units derived from at least one (meth)acrylic monomer [monomer (MA)] having formula (I) here below: wherein: R1, R2 and R3, equal to or different from each other, are independently selected from a hydrogen atom and a C1-C3 hydrocarbon group, and ROH represents a hydrogen atom or a C1-C5 hydrocarbon moiety comprising at least one hydroxyl group, said polymer (F) comprising end groups having formula —CF2H and/or —CF2CH3 in an amount of at least 30 mmoles per Kg of vinylidene fluoride (VDF) recurring units. The invention also pertains to a process for the manufacture of said polymer (F) and to use of said polymer (F) as binders for the manufacture of electrodes or for the manufacture of membranes.
US09441045B2 Affinity matured anti-CCR4 humanized monoclonal antibodies and methods of use
The present invention provides affinity matured humanized monoclonal antibodies, bi-specific antibodies, antibody conjugates, and fusion proteins that bind to the chemokine receptor CCR4. This antibody is derived from mAb 1567 and recognizes the same epitope. Binding of the antibodies disclosed herein to CCR4 inhibits ligand-mediated activities and is used to treat symptoms of cancer. Moreover, the antibody is used in combination with vaccines to suppress the activity of regulatory T cells.
US09441042B2 Anti-KDR antibodies and methods of use
The present invention provides anti-KDR monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of a variety of cancers, rheumatoid arthritis, diabetic retinopathy and other diseases associated with aberrant VEGF or KDR expression and/or activity.
US09441041B2 Use of antagonists of the interaction between HIV GP120 and α4β7 integrin
Methods are provided for the treatment of a HIV infection. The methods can include administering to a subject with an HIV infection a therapeutically effective amount of an agent that interferes with the interaction of gp120 and α4 integrin, such as a α4β1 or α4β7 integrin antagonist, thereby treating the HIV infection. In several examples, the α4 integrin antagonist is a monoclonal antibody that specifically binds to a α4, β1 or β7 integrin subunit or a cyclic hexapeptide with the amino acid sequence of CWLDVC. Methods are also provided to reduce HIV replication or infection. The methods include contacting a cell with an effective amount of an agent that interferes with the interaction of gp120 and α4 integrin, such as a α4β1 or α4β7 integrin antagonist. Moreover, methods are provided for determining if an agent is useful to treat HIV.
US09441031B2 Oriented collagen/apatite material and method for producing oriented collagen/apatite material
It is an object of the present invention to provide an oriented collagen/apatite material wherein an orientation is controlled, and a method of the oriented collagen/apatite material wherein an orientation is controlled. A method of producing an orientated collagen/apatite material according to the present invention, is characterized in that the method comprises; preparing a collagen having an orientation, seeding an osteoblast or a mesenchymal stem cell to produce and fix an apatite having an orientation similar to or almost the same as a direction of an orientation of the collagen on a surface and/or inside of the collagen. Furthermore, in a preferred embodiment of above mentioned method of producing an orientated collagen/apatite material according to the present invention, is characterized in that the osteoblast is an osteoblast like cell or an osteoblast obtained from a living organism.
US09441030B2 Process for producing and purifying factor VIII and its derivatives
Disclosed is a method for producing proteins having factor VIII procoagulant activity in serum-free medium by in vitro culturing of mammalian cells, wherein the serum-free medium contains an inhibitor against the protease released from cultured cells. In accordance with this invention, the inhibitor can protect the cleavage of a target protein during cultivation and increase homogeneity of a target molecule, wherein the inhibitor can be a dextran sulfate. This invention also relates to a method of purifying target molecules from the culture medium containing both a target molecule and selected inhibitors by affinity chromatography.
US09441028B2 Counter current purification of polypeptides
The present invention relates to methods for the purification of polypeptides using counter current chromatography. In particular the present invention relates to the use of counter current chromatography for the purification of recombinant GLP-1.
US09441026B2 Polypeptides targeting vascular endothelial growth factor receptor-2 and alpha V beta 3 integrin
Polypeptides comprising variant vascular endothelial growth factor sequences are provided. The polypeptides are useful in cancer imaging, cancer diagnosis, monitoring and treatment as well as treatment of diseases characterized by excessive neovascularization.
US09441024B2 Glycosylated polypeptide and drug composition containing said polypeptide
[Problem] To provide a glycosylated polypeptide having affinity to somatostatin receptors and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least two amino acids in a somatostatin or an analogue thereof being replaced by glycosylated amino acids.
US09441021B2 Process for the preparation of hypoallergenic major birch pollen allergen rBet v 1
The invention relates to a process for the preparation of hypoallergenic major birch pollen allergens by means of one or more chromatographic purification steps using essentially unbuffered aqueous bases as eluent and subsequent neutralization. The hypoallergenic major birch pollen allergens are distinguished by a lack of, but at least by reduced immunoglobulin E binding with simultaneous retention of therapeutically relevant T-cell stimulation. They can therefore be employed as low-side-effect therapeutic agents for specific immunotherapy.
US09441017B2 Water-soluble polypeptides comprised of repeat modules, method for preparing the same and method for a target-specific polypeptide and analysis of biological activity thereof
The present invention relates to a soluble polypeptide comprised of repeat modules. More particularly, the present invention relates to a soluble fusion polypeptide of the N-terminal domain of internalin and LRR (Leucine rich repeat) family protein, a method for preparing the polypeptide, a vector comprising a nucleic acid sequence encoding the polypeptide, a host cell comprising the vector, a method for producing a solubility and folding-improved fusion polypeptide by expressing the vector in the host cell, and a method for improving the solubility and folding of the fusion polypeptide. Further, the present invention relates to a method for preparing the polypeptide bound with a specific target and analyzing the efficacy of the soluble polypeptide.
US09441015B2 Recombinant fusion antigen gene, recombinant fusion antigen protein and subunit vaccine composition having the same against infection of porcine reproductive and respiratory syndrome virus
The present invention is directed to a recombinant fusion antigen gene, a recombinant fusion antigen protein and a subunit vaccine composition having the same against infection of porcine reproductive and respiratory syndrome virus (PRRSV). A recombinant fusion antigen gene, which encodes glycoprotein GP5 with truncated N′-terminal decoy epitope, a linker sequence and membrane protein M, followed by codon optimization, is expressed by a baculovirus expression system in vitro, thereby enhancing a yield of the recombinant fusion antigen protein. The recombinant fusion antigen protein can be applied in a subunit vaccine composition, for providing vaccinated animals with better protection ability without the risks of virulent spread and virulent recovery.
US09441013B2 Melanocortin 1 receptor ligands and methods of use
The subject invention pertains to a modified MC1R peptide ligand comprising a peptide that is a melanocortin 1 receptor (MC1R) ligand and a functionality or linker, such as a click functionality, for conjugation to a surface or agent. The modified MC1R peptide ligand can be coupled, e.g., via a click reaction with a complementary click functionality attached, to a moiety to form an MC1R-targeted agent. Drugs, contrast agents, polymers, particles, micelles, surfaces of larger structures, or other moieties can be targeted to the MC1R. The subject invention also pertains to a MC1R peptide ligand-micelle complex comprising a peptide that is a melanocortin 1 receptor ligand connected via a click reaction product to a micelle. The micelle is stable in vivo and can target melanoma tumor cells by association of the peptide ligand with the MC1R or the tumor and selectively provide a detectable and/or therapeutic agent (such as an imageable contrast agent and/or anti-cancer agent) selectively to the tumor cell.
US09441011B2 Method for purification of antibody using porous membrane having amino group and alkyl group both bound to graft chain immobilized on porous substrate
A method is disclosed for purifying an antibody monomer, comprising providing a porous membrane comprising a hydrophobic porous substrate, a hydrophilic molecular chain of a different material from that of the porous substrate, immobilized on the surface of pores of the porous substrate, and a side chain of the molecular chain, containing a nitrogen atom to which one to three alkyl groups each having two or three carbon atoms are bonded; passing an antibody solution containing antibody aggregates of dimers or higher-order multimers through the porous membrane to adsorb the antibody aggregates to the porous membrane; and recovering the purified antibody monomer in the passed solution.
US09441001B2 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom
There is provided herein a method of making hydroxymethylphosphonate comprising reacting paraformaldehyde, at least one dialkyl phosphite and at least one trialkyl phosphite, in the presence of at least one amine catalyst.
US09441000B2 Use of metallocene compounds for cancer treatment
Metallocene compounds and pharmaceutical compositions containing these metallocene compounds are disclosed and described. Methods of treating cancer employing such metallocene compounds and pharmaceutical compositions also are provided.
US09440999B2 Activation of metal salts with silylhydrides and their use in hydrosilylation reactions
The invention relates generally to transition metal salts, more specifically to iron, nickel, cobalt, manganese and ruthenium salts, activated with silylhydrides, and their use as efficient hydrosilylation catalysts.
US09440990B2 1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases
The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof. The present invention relates to a compound represented by the formula (I) wherein each symbol is as defined in the specification, or a salt thereof.
US09440989B2 Antifibrinolytic compounds
It relates to spirocyclic compounds of formula (I), or pharmaceutically or veterinary acceptable salts thereof, or any stereoisomers either of the compounds of formula (I) or of their pharmaceutically or veterinary acceptable salts, wherein A and B form a spirocyclic ring system wherein the spiro atom connecting A and B is a carbon atom and wherein A is a known 3- to 8-membered carbocyclic or heterocyclic monocyclic ring or a known 6- to 18-membered carbocyclic or heterocyclic polycyclic ring system; B is a known 4- to 7-membered carbocyclic or heterocyclic monocyclic ring; C is phenyl or a known 5- to 6-membered heteroaromatic ring; and R1-R7 are as defined herein. It also relates to a process for their preparation, as well as to the intermediates used in this process; to pharmaceutical or veterinary compositions containing them, and to their use in medicine, in particular as antifibrinolytic and antihemorragic agents.
US09440988B2 Regulators of the hedgehog pathway, compositions and uses related thereto
The present invention makes available, inter alia, methods and reagents for modulating smoothened-dependent pathway activation. In certain embodiments, the subject methods can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function mutations.
US09440983B2 Pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione derivatives
This invention relates to novel Pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione derivatives of Formula (I): and their use as TRPC5 modulators, pharmaceutical compositions containing the same, and methods of using the same as agents for the treatment of TRPC5 receptor mediated disorders or conditions. R1, R2, R3 R4 and R5 have meanings given in the description.
US09440981B2 Pyrrolo[2, 1-F] [1,2,4]triazine derivative and use thereof for treating tumors
Disclosed are a pyrrolo[2,1-f][1,2,4]triazine derivative of Formula (I) and use thereof for treating tumors. The compound has remarkable antiproliferative activity for a variety of human tumor cell lines, and is useful for treating cancers, especially solid tumors such as gastric cancer, lung cancer, liver cancer, breast cancer, colon cancer, prostatic cancer, and oral cancer.
US09440977B2 Compositions, uses and methods for their preparation
The present invention relates to novel compounds and pharmaceutical compositions thereof which may be useful in the treatment and/or prevention of various conditions. The present invention also provides methods of preparing such compounds and compositions, and methods of using the same.
US09440974B2 Kinase inhibitors
Compounds of formula (I) described herein are p38 MAPK inhibitors and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
US09440971B2 Solid state forms of vemurafenib hydrochloride
Provided herein are solid state forms of Vemurafenib hydrochloride, processes for preparing the solid state forms, as well as pharmaceutical compositions and formulations comprising said solid state forms.
US09440969B2 Compounds and methods for kinase modulation, and indications therefor
Compounds and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof are described. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof are active on each of B-Raf, B-Raf V600E and c-Raf-1 protein kinase. In certain aspects and embodiments, the described compounds are active in inhibiting proliferation of a Ras mutant cell line. Also described are methods of use thereof to treat diseases and conditions, including melanoma, glioma, glioblastoma, pilocytic astrocytoma, liver cancer, biliary tract cancer, cholangiocarcinoma, colorectal cancer, lung cancer, bladder cancer, gallbladder cancer, breast cancer, pancreatic cancer, thyroid cancer, kidney cancer, ovarian cancer, adrenocortical cancer, prostate cancer, gastrointestinal stromal tumors, medullary thyroid cancer, tumor angiogenesis, acute myeloid leukemia, chronic myelomonocytic leukemia, childhood acute lymphoblastic leukemia, plasma cell leukemia, and multiple myeloma.
US09440965B2 Process for the synthesis of benzothiadiazole compounds
The invention relates to a significantly improved process for the preparation of benzothiadxazole compounds which can be used in the production of Luminescent Solar Concentrators, (LSC). In particular, the synthesis process of the present invention is oriented towards the preparation of 4,-di-2-thienyl-2,1,3-benzo-thiadiazole.
US09440964B2 Pesticidal compositions and processes related thereto
This document discloses molecules having the following formula (“Formula One”) The molecules disclosed in this document are related to the field of processes to produce molecules that are useful as pesticides (e.g., acaricides, insecticides, molluscicides, and nematicides), such molecules, and processes of using such molecules to control pests.
US09440963B2 Compositions, formulations and methods for treating ocular diseases
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
US09440962B2 Benzisoxazoles
The present invention relates to compounds of general formula wherein Ar1/Ar2 are phenyl or a 5 or 6-membered heteroaryl; R1/R2 is hydrogen, halogen, lower alkyl, CF3 or lower alkoxy; n,m are 1 or 2; or to a pharmaceutically acceptable acid addition salt, to a racemic mixture or to its corresponding enantiomer and/or optical isomers thereof, with the exception of the compound 2,1-benzisoxazole, 3-(4-chlorophenyl)-5-(1-phenyl-1H-pyrazol-5 -yl)-. The compounds may be used for the treatment of schizophrenia, obsessive-compulsive personality disorder, major depression, bipolar disorders, anxiety disorders, normal aging, epilepsy, retinal degeneration, traumatic brain injury, spinal cord injury, post-traumatic stress disorder, panic disorder, Parkinson's disease, dementia, Alzheimer's disease, mild cognitive impairment, chemotherapy-induced cognitive dysfunction, Down syndrome, autism spectrum disorders, hearing loss, tinnitus, spinocerebellar ataxia, amyotrophic lateral sclerosis, multiple sclerosis, Huntington's disease, stroke, radiation therapy, chronic stress, abuse of neuro-active drugs, such as alcohol, opiates, methamphetamine, phencyclidine and cocaine.
US09440960B2 Substituted oxetanes and their use as inhibitors of cathepsin C
This invention relates to a compound of formula I and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
US09440956B2 Indole, indazole and benzimidazole arylamides as P2X3 and P2X2/3 antagonists
Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, X, Y, Z, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.
US09440954B2 Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors
Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols according to formula (I) are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme.
US09440953B2 Substituted amino triazoles useful as acidic mammalian chitinase inhibitors
Disclosed are amino triazole compounds substituted by a carboxylate functional group or an bioisosteric polar functional group. Compounds having the carboxylate moiety or carboxylate bioisostere inhibit acidic mammalian chitinase. Also provided are methods of using the compounds to treat asthma reactions caused by allergens.
US09440952B2 Compounds inhibiting leucine-rich repeat kinase enzyme activity
The present invention is directed to indazole compounds which are potent inhibitors of LRRK2 kinase and useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK-2 kinase is involved.
US09440941B2 Substituted chroman-6-yloxy-cycloalkanes and their use as pharmaceuticals
The present invention relates to substituted chroman-6-yloxy-cycloalkanes of the formula (I) in which Ar, R1 to R4, p and q are as defined in the claims. The compounds of the formula (I) are inhibitors of the sodium-calcium exchanger (NCX), especially of the sodium-calcium exchanger of subtype 1 (NCX1), and are suitable for the treatment of diverse disorders in which intracellular calcium homeostasis is disturbed, such as arrhythmias, heart failure and stroke. The invention furthermore relates to processes for the preparation of the compounds of the formula (I), their use as pharmaceuticals, and pharmaceutical compositions comprising them.
US09440940B2 Methods for synthesis of psoralen derivatives
Methods for the synthesis of psoralen derivatives are provided. In one embodiment, the method may include acetylating a compound of formula (II) to form a compound of formula (III), subjecting the compound of formula (III) to a Fries rearrangement to form a compound of formula (IV), and subjecting the compound of formula (IV) to cyclization, reduction and aromatization, to form a compound having the following formula (I):
US09440938B2 Sulfonamide derivative having PGD2 receptor antagonistic activity
The present invention provides an sulfonamide derivative having DP receptor antagonistic activity and a pharmaceutical composition comprising the said compound as an active ingredient, and further a therapeutic agent for treating allergic diseases.A compound of the general formula (II): wherein the ring A is an aromatic carbocyclic ring etc.; the ring B is a nitrogen-containing non-aromatic heterocyclic ring etc.; the ring C is an aromatic carbocyclic ring etc.; R1 is carboxy etc.; R2 is independently a halogen atom etc.; R3 is optionally substituted alkyloxy etc.; R4 is independently a halogen atom etc.; R5 is independently optionally substituted alkyl etc.; M is sulfonyl etc.; Y is a single bond etc.; L1 is a single bond etc.; L2 is a single bond etc.; k is 0, 1, 2, 3 or 4; n is 0, 1 or 2; and q is 0, 1, 2 or 3; provided that a) k is not 0 when the ring B is a 6-membered nitrogen-containing heterocyclic ring containing one or two nitrogen atom(s) and the ring C is a benzene ring, etc.; a pharmaceutically acceptable salt or a hydrate thereof.
US09440925B2 SDP-containing heterobifunctional agents
The present disclosure is directed to a reactive ester agent for conjugating a click-reactive group to a carrier molecule or solid support. The reactive ester agent has the general formula IA, wherein the variables R1, R2, R3, Ra and L are described throughout the application.
US09440921B2 3-N-butyl-1-isoindolinone and use thereof for preventing or treating cerebral infarction
3-n-Butyl-1-isoindolinone and use thereof for preventing or treating cerebral infarction. The compound is prepared by: 1) employing phthalimide as a starting reactant, contacting a nucleophilic Grignard reagent with the original reactant to add an alkyl group to a carbonyl carbon of an amide bond of the original reactant, thus yielding an intermediate; and 2) removing an oxygen atom connected to a third carbon atom of the intermediate in the presence of boron trifluoride diethyl etherate as a catalyst and triethylsilane as a reductant.
US09440919B2 Difluorolactam compositions for EP4-mediated osteo related diseases and conditions
Disclosed herein are compositions and methods of treating osteoporosis, bone fracture, bone loss, and increasing bone density by administration of compounds of formula (I) or compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier, wherein L1, L2, L4, R1, R4, R5, R6, and s are as defined in the specification.
US09440918B2 Method for purifying (S)-Oxiracetam
A method for purifying (S)-oxiracetam is disclosed. Crude (S)-oxiracetam with the purity of 89% is dissolved in water; the solution is allowed to stand for 1 to 3 days at 0° C. to 18° C.; a colorless transparent crystal is precipitated; the solution is filtered and top-washed with cold water to 0° C. to 5° C.; and the product is dried in vacuum to obtain high-purity (S)-oxiracetam.
US09440915B2 Method for preparing methanedisulfonic acid
Disclosed is a method for preparing methanedisulfonic acid, comprising an acidification, wherein the acidification comprises that methanedisulfonate reacts with an acidifier to form a mixture containing methanedisulfonic acid. The disclosure has high yield, low cost, and the process are environmental friendly.
US09440913B2 Dihydroxybenzene derivatives and antiprotozoal agent comprising same as active ingredient
Novel compounds below are useful for preventing or treating diseases caused by protozoans. At least one of a compound represented by Formula (I) (wherein, X represents a hydrogen atom or a halogen atom; R1 represents a hydrogen atom; R2 represents a hydrogen atom or a C1-7 alkyl group; R3 represents —CHO, —C(═O)R5, —COOR5 (wherein R5 represents a C1-7 alkyl group), —CH2OH or —COOH; and R4 represents a C1-16 alkyl group having one or more substituents on a terminal carbon atom and/or non-terminal carbon atom(s), a C2-16 alkenyl group having one or more substituents on a terminal carbon atom and/or non-terminal carbon atom(s), or a C2-16 alkynyl group having one or more substituents on a terminal carbon atom and/or non-terminal carbon atom(s)), an optical isomer thereof, and a pharmaceutically acceptable salt is used.
US09440912B2 Pentenenitrile isomerization
Disclosed is a process for isomerizing cis-2-pentenenitrile to 3-pentenenitrile in the presence of a non-aluminum metal oxide catalyst, wherein: (a) the metal in the catalyst has an oxidation state in the range from +1 to +4; (b) the metal has a cation radius in the range from 0.35 to 1.0 Å; (c) the metal of the catalyst has a polarizing power, C/r, is in the range from 2 to >8, wherein C is the charge of the metal and r is the ionic radius in Å; (d) the bond network of the catalyst has a % ionicity of >20; (e) the metal oxide has an acidity strength in the range from strong to very weak; and (f) the metal oxide has a basicity (nucleophilicity) strength of weak to strong.
US09440909B2 Sulfide scavengers, methods for making and methods for using
Methods for making sulfide scavenging compositions are provided. The method comprises reacting at least one secondary amine with at least one aldehyde and solvent in the presence of a catalyst to form a reaction composition, wherein a reaction temperature is less than or equal to 90° C. Sulfide scavengers using the above method are also disclosed. Methods for removing sulfides from fluid streams are also provided. The methods include adding the above sulfide scavengers to fluid streams.
US09440908B2 Process for preparing N-(5-chloro-2-isopropylbenzyl)cyclopropanamine
The present invention relates to a process for preparing N-(5-chloro-2-isopropylbenzyl)cyclopropanamine by hydrogenation of N-[(5-chloro-2-isopropylphenyl)methylene]cyclopropanamine over specific platinum catalysts.
US09440907B2 Production method for 2-alkenylamine compound
Provided is a method for producing a 2-alkenylamine compound efficiently and at low cost, using a primary or secondary amine compound and a 2-alkenyl compound as the starting materials therefor. The 2-alkenylamine compound is produced by adding Bronsted acid when 2-alkenylating by reacting the primary or secondary amine compound with the 2-alkenyl compound, and 2-alkenylating in the presence of a catalyst comprising a complexing agent and a transition metal precursor stabilized by a monovalent anionic five-membered conjugated diene.
US09440906B2 Crystalline ingenol mebutate
The present invention relates to a novel crystalline form of ingenol mebutate, methods of preparation thereof, and to its use. More specifically, the invention relates to the conversion of amorphous ingenol mebutate (ingenol-3-angelate, PEP005) to a crystalline form, which was characterized by single crystal X-Ray crystallography (XRC), attenuated total reflectance Fourier transform infrared (FTIR-ATR) spectroscopy and Differential Scanning calorimetry (DSC).
US09440902B2 Method for producing carbonyl compound
To provide a production method for suppressing the reduction in production rate of a carbonyl compound due to transferring a noble metal component into liquid phase. A method for producing a carbonyl compound, including: a reaction step of reacting a carbonylation raw material with CO in liquid phase including a solid catalyst having noble metal complex on a resin carrier containing quaternized nitrogen to produce a carbonyl compound; a distillation step of distilling a reaction product liquid to recover gas phase distillate including the carbonyl compound; and a circulation step of circulating a bottom product from the distillation to reaction step. After part of the bottom product contacts with an acidic cation-exchange resin to remove nitrogen compound, liquid having higher moisture concentration than the bottom product contacts with the resin to extract noble metal complex captured by oligomer adsorbing the resin, and the complex is returned to the reaction step.
US09440900B2 α,α-difluoroacetaldehyde production method
A production method of α,α-difluoroacetaldehyde according to the present invention includes reaction of an α,α-difluoroacetic acid ester with hydrogen gas (H2) in the presence of a ruthenium catalyst. It is possible to selectively obtain α,α-difluoroacetaldehyde as a partially reduced product of the hydrogenation reaction by the adoption of specific reaction conditions (in particular, reaction solvent and reaction temperature). This hydrogenation process can be alternative to the industrially unpractical hydride reduction process.
US09440896B2 Dehydrochlorination of HCFC-336 isomers to 1,1,1,4,4,4-hexafluoro-2-butyne
Disclosed is a process for producing hexafluoro-2-butyne comprising, reacting HCFC-336 with an aqueous solution of an alkali metal hydroxide in the presence of a quaternary alkylammonium salt which comprises at least one alkyl group of at least 8 carbons, and recovering the hexafluoro-2-butyne, wherein the conversion of dichloro-1,1,1,4,4,4-hexafluorobutane is at least 50% per hour. Also disclosed is a process for producing hexafluoro-2-butyne comprising, reacting HCFC-336 with an aqueous solution of an alkali metal hydroxide in the presence of a quaternary alkylammonium salt having alkyl groups of from four to ten carbon atoms, and mixtures thereof, and a non-ionic surfactant, and recovering the hexafluoro-2-butyne, and wherein the conversion of dichloro-1,1,1,4,4,4-hexafluorobutane to hexafluoro-2-butyne is at least 20% per hour.
US09440894B2 Integration of residue hydrocracking and hydrotreating
A process for upgrading residuum hydrocarbons is disclosed. The process may include: contacting a residuum hydrocarbon fraction and hydrogen with a first hydroconversion catalyst in a first ebullated bed hydroconversion reactor system; recovering a first effluent from the first ebullated bed hydroconversion reactor system; solvent deasphalting a vacuum residuum fraction to produce a deasphalted oil fraction and an asphalt fraction; contacting the deasphalted oil fraction and hydrogen with a second hydroconversion catalyst in a second hydroconversion reactor system; recovering a second effluent from the second hydroconversion reactor system; and fractionating the first effluent from the first ebullated bed hydroconversion reactor system and the second effluent from the second hydroconversion reactor system to recover one or more hydrocarbon fractions and the vacuum residuum fraction in a common fractionation system.
US09440891B2 Palladium-catalyzed decarbonylation of fatty acid anhydrides for the production of linear alpha olefins
The present invention is directed to methods of forming olefins, especially linear alpha olefins from fatty acids or anhydrides, each method comprising: contacting an amount of precursor carboxylic acid anhydride with a palladium catalyst comprising a bidentate bis-phosphine ligand in a reaction mixture so as to form an olefin in a product with the concomittant formation and removal of CO and water from the reaction mixture, either directly or indirectly, wherein the reaction mixture is maintained with a sub-stoichiometric excess of a sacrificial carboxylic acid anhydride, an organic acid, or both, said sub-stoichiometric excess being relative to the amount of the precursor carboxylic acid anhydride. The precursor carboxylic acid anhydride may be added to the reaction mixture directly or formed in situ by the reaction between at least one precursor carboxylic acid with a stoichiometric amount of the sacrificial acid anhydride.
US09440887B2 Silicon nitride sintered body and wear resistant member using the same
The present invention provides a silicon nitride sintered body comprising a silicon nitride crystalline particle and a grain boundary phase, the silicon nitride sintered body having an area ratio of the grain boundary phase per 100 μm×100 μm unit area of 15 to 35% when an arbitrary cross section thereof is photographed. Further, it is preferable that the area ratio of the grain boundary phase per 100 μm×100 μm unit area is 15 to 25%. Furthermore, the silicon nitride sintered body is suitable for a wear resistant member. Due to above structure, there can be provided a silicon nitride sintered body and a wear resistant member having a high processability (workability) and an excellent sliding property.
US09440886B2 Rare-earth oxide based monolithic chamber material
A solid sintered ceramic article may include a solid solution comprising Y2O3 at a concentration of approximately 30 molar % to approximately 60 molar %, Er2O3 at a concentration of approximately 20 molar % to approximately 60 molar %, and at least one of ZrO2, Gd2O3 or SiO2 at a concentration of approximately 0 molar % to approximately 30 molar %. Alternatively, the solid sintered ceramic article a solid solution comprising 40-100 mol % of Y2O3, 0-50 mol % of ZrO2, and 0-40 mol % of Al2O3.
US09440884B1 Epoxy grout systems for standard and chemically resistant installations
An epoxy grout system comprises a first epoxy resin component comprising a novolac epoxy resin, a bisphenol F epoxy resin, and a non-reactive diluent, and a second epoxy curing agent component comprising an amidoamine. The epoxy grout system has excellent chemical resistance while maintaining good installation properties. Another epoxy grout system comprises a first epoxy resin component which is resistant to a mixture of oleic acid and water, a second epoxy resin component which is less resistant to a mixture of oleic acid and water than the first component, and a third amine-containing curing agent component operable to cure both the first and second epoxy resin components. Optionally, the curing agent component can be provided as a plurality of amine-containing curing agent components of respective colors, whereby a user can select a curing agent component of a desired color for use with either the first or second epoxy resin component.
US09440880B2 Method of manufacturing light-emitting device
A method of manufacturing a sealed structure with excellent hermeticity and a method of manufacturing a light-emitting device sealed with the sealed structure. In the methods of manufacturing a sealed structure and a light-emitting device using a glass frit layer, a first step of forming a buffer layer for preventing a crack generated in a substrate and the glass frit layer by laser light irradiation, a second step of forming the glass frit layer to overlap with the buffer layer over the substrate, and a third step of welding the substrates by irradiating the glass frit layer or the buffer layer with laser light are performed, whereby a sealed structure with high hermeticity and a reliable light-emitting device sealed with the sealed structure can be manufactured. By applying the method of manufacturing a light-emitting device especially to an organic EL element, a highly reliable light-emitting device can be obtained.
US09440876B2 Electron sensitive glass and optical circuits, microstructures formed therein
An electron definable glass or an electron sensitive glass for microstructures is provided with microstructures and optical waveguides formed therein. The microstructures are formed by electron beam irradiation in selected areas in the electron definable glass followed by a high temperature heat treatment and chemical etching, whereas the optical waveguides are formed by irradiating the electron definable glass by an electron beam followed by a low temperature heat treatment.
US09440875B2 Glass composition having high thermal and chemical stability
Described herein are alkali-free, boroalumino silicate glasses exhibiting desirable physical and chemical properties for use as substrates in flat panel display devices, such as, active matrix liquid crystal displays (AMLCDs) and active matrix organic light emitting diode displays (AMOLEDs). In accordance with certain of its aspects, the glasses possess good dimensional stability as a function of temperature.
US09440874B2 Glass base material elongating method and glass base material elongating apparatus
Provided is a glass base material elongating method of using a glass base material elongation apparatus including a heating furnace, a feeding mechanism, and a pulling mechanism to elongate the rod-shaped glass base material to form a thinner glass rod, the method comprising gripping a pulling dummy rod connected to a bottom end of the glass base material with first pulling rollers of the pulling mechanism and, together with the feeding mechanism, feeding the glass base material to the heating furnace; and before a pulling force necessary for pulling the pulling dummy rod to elongate the glass base material reaches a load force that causes slipping between the pulling dummy rod and the first pulling rollers, gripping and pulling the pulling dummy rod with second pulling rollers of the pulling mechanism in addition to the first pulling rollers.
US09440873B2 Method for cooling optical fiber
In one embodiment, an optical fiber cooling system includes a first cooling tube oriented substantially in parallel with and spaced apart from a second cooling tube such that an optical fiber pathway is positioned between the first cooling tube and the second cooling tube. The first cooling tube includes a plurality of cooling fluid outlets positioned along an axial length of the first cooling tube which are oriented to direct a flow of cooling fluid across the optical fiber pathway towards the second cooling tube. The second cooling tube includes a plurality of cooling fluid outlets positioned along an axial length of the second cooling tube which are oriented to direct a flow of cooling fluid across the optical fiber pathway towards the first cooling tube.
US09440871B2 Treatment agent for salt-containing organic waste liquid, salt concentration-reducing agent, treatment method for salt-containing organic waste liquid, and entrapment immobilization carrier
A treatment agent for salt-containing organic waste liquid, the treatment agent including: Scuticociliatida, wherein the treatment agent treats salt-containing organic waste liquid; and a treatment method for salt-containing organic waste liquid, the treatment method including: bringing Scuticociliatida and salt-containing organic waste liquid into contact with each other to treat the salt-containing organic waste liquid.
US09440862B1 Method and apparatus for accelerated open air evaporation of wastewater
A device and method of accelerating the evaporation of wastewater and concentration of solids wherein an evaporative material contacts wastewater allowing the wastewater to migrate onto the surface of the evaporative material where the sun and wind evaporates the wastewater in an accelerated manner due to the configuration of the evaporative material.
US09440859B2 Silicon carbide powder comprising alpha phase silicon carbide granules of trimodal particle size distribution and low impurities
A silicon carbide powder includes at least one group selected from a first group comprising an alpha phase silicon carbide pulverulent body of which a granule size (D50) is greater than 0 μm and less than 45 μm with impurities less than 10 ppm, a second group comprising an alpha phase silicon carbide pulverulent body of which a granule size is greater than 45 μm and less than 75 μm with impurities less than 10 ppm, and a third group comprising an alpha phase silicon carbide pulverulent body of which a granule size is greater than 75 μm and less than 110 μm with impurities less than 10 ppm. In addition, a method for preparing a silicon carbide powder includes adding seeds to a beta silicon carbide powder, and forming an alpha silicon carbide powder by heat treating the beta silicon carbide powder.
US09440858B2 Carbon particles
A composition generally includes carbon particles. The particles are prepared by dissolving a carbohydrate-based precursor in water to form a precursor solution and placing the precursor solution in a pressure vessel. The precursor solution is placed in a pressure vessel. The pressure vessel is heated to a reaction temperature to form carbon particles. The carbon particles are subjected to a chemical activation and a physical activation. The composition includes, by weight, about 5% to about 30% oxygen.
US09440856B2 Process for producing graphene
A process for producing graphene by providing a plurality of metallic particles as templates for graphene formation and providing a carbon source; reacting the metallic particles and carbon source under conditions suitable for graphene formation; and forming graphene particles on the metallic particles. The graphene particles formed on the metallic particles are of a size and shape substantially corresponding to the size and shape of the metallic particles.
US09440854B2 Chiral or achiral, mesoporous carbon
A composition and a method for producing mesoporous carbon materials with a chiral or achiral organization. In the method, a polymerizable inorganic monomer is reacted in the presence of nanocrystalline cellulose to give a material of inorganic solid with cellulose nanocrystallites organized in a chiral nematic organization. The cellulose can be carbonized through thermal treatment under inert atmosphere (e.g., nitrogen or argon) and the silica may subsequently be removed using aqueous solutions of sodium hydroxide (NaOH) or hydrogen fluoride (HF) to give the stable mesoporous carbon materials that retain the chiral nematic structure of the cellulose. These materials may be obtained as free-standing films with very high surface area. Through control of the reaction conditions the pore-size distribution may be varied from predominantly microporous to predominantly mesoporous materials. These are the first materials to use cellulose as both the structural template and carbon source for a mesoporous carbon material. These are also the first carbon materials to combine mesoporosity with long-range chiral ordering. Possible applications for these materials include: charge storage devices (e.g. supercapacitors and anodes for Li-ion batteries), adsorbents, gas purifiers, light-weight nanocomposite materials, catalyst supports (e.g., for chiral transformations), gas storage, and as a hard-template to generate other materials, preferably with chiral structures.
US09440850B2 Carbon material for hydrogen storage
The present invention relates to carbon based materials that are employed for hydrogen storage applications. The material may be described as the pyrolysis product of a molecular precursor such as a cyclic quinone compound. The pyrolysis product may then be combined with selected transition metal atoms which may be in nanoparticulate form, where the metals may be dispersed on the material surface. Such product may then provide for the reversible storage of hydrogen. The metallic nanoparticles may also be combined with a second metal as an alloy to further improve hydrogen storage performance.
US09440849B2 Nanoparticle organic hybrid materials (NOHMS)
A nanoparticle organic hybrid material (NOHM) containing an organic polymeric corona having a molecular weight in a range of 100-50,000 g/mol, wherein the organic polymeric corona is covalently attached to an inorganic nanoparticle core, wherein the NOHM exhibits liquid-like properties so that the NOHM moves freely and flows in a manner so that when the NOHM is in a container, the NOHM takes the shape of the container, and wherein the NOHM has a volume fraction (fc) of the inorganic particle ranging from about 0.05 to 0.75, methods of making the NOHMs, and compositions containing the NOHMs.
US09440846B2 System on a chip using integrated MEMS and CMOS devices
An integrated MEMS system in which CMOS and MEMS devices are provided to form an integrated CMOS-MEMS system. The system can include a silicon substrate layer, a CMOS layer, MEMS and CMOS devices, and a wafer level packaging (WLP) layer. The CMOS layer can form an interface region, one which any number of CMOS MEMS devices can be configured.
US09440840B2 Water dispenser
A water dispenser includes a raw water container having an inner tube a water outlet port of the raw water container. The inner tube is provided with a stepped portion having a smaller diameter at its portion closer to the interior of the raw water container, and a fastening belt portion formed contiguous to the stepped portion on the smaller diameter side thereof. The water server also includes a joint portion in the form of a cylindrical member including a straight portion (73) configured to be fitted tightly to the fastening belt portion, and provided with a water flow hole formed in a size so as not to cover the entire axial width of the fastening belt portion while the straight portion is being inserted into the fastening belt portion.
US09440839B1 Preferential distribution of cooling capacity
A cooling system for a beverage comprises an enclosure for housing a beverage container, a cold plate through which the beverage flows, and a refrigeration system that controllably cools the enclosure and the cold plate in a differential manner. In preferred embodiments, preference is given during normal operation to cooling the cold plate, and only cooling the enclosure when the cold plate is determined to be at or below a desired temperature. In some embodiments a special defrost cycle warms the cold plate while continuing to cool the enclosure. Controls can be mechanical, electronic or any combination of the two, and preferably utilizes information from both pressure and temperature sensors.
US09440838B1 Interactive liquid drip catcher for bag-in-the-box liquid containers
An interactive device for catching drips from a spout commonly associated with bag-in-the-box liquid containers. The apparatus attaches to features of the spout and a pendulum element blocks access to the liquid flow path beneath the spout. A cup makes contact with the pendulum, forcing it aside to gain access to the liquid flow path. The pendulum returns beneath the spout, via gravity, when interaction is complete.
US09440837B2 Beverages dispenser and a method for dispensing beverages
A beverages dispenser, particularly for carbonated beverages, comprises a cooled tank where beverage is stored, an inlet pipe to the tank, an inlet valve on the inlet pipe, a pump downstream the inlet valve for feeding a beverage to the tank in order to maintain a predetermined level wherein, an outlet pipe from the tank to a beverage dispensing nozzle, and an outlet valve on the outlet conduit. An auxiliary pipe is disposed between the inlet pipe downstream the inlet valve and the outlet pipe downstream the outlet valve and a control unit is adapted to close the inlet valve and to run the pump in order to empty the outlet pipe into the tank after the beverage is dispensed in order to prevent dripping.
US09440835B2 Fluid transfer assembly and methods of fluid transfer
A fluid dispensing assembly, including a valve, a housing, a user interface, and a fitting to couple to a fluid source. The valve may include a first sensor detecting proper placement of the fluid container based on a magnetic material positioned at the bottom of the fluid container, a plunger having a plunger shaft coupled thereto, the plunger selectively placing the valve in fluid communication with the fluid container, and a solenoid coupled to the plunger shaft and moving the plunger shaft to transition the plunger between an open position and a closed position. The user interface may be coupled to the valve to enable selection of at least a fluid container size and a dispensing mode.
US09440822B2 Wheel transporting assembly
A wheel transporting assembly includes a cradle. The cradle comprises a central section, a top section and a bottom section each coupled to and extending away from the central section. The cradle may engage a wheel while the wheel is mounted on a vehicle. The cradle avoids contact with a body of the vehicle while the wheel is removed from the vehicle. A mount is coupled to the cradle. The mount may be engaged to a lift to facilitate the wheel to be transported away from the vehicle. A loop is coupled to the cradle. The loop may have a cord coupled between the loop and the wheel to facilitate the wheel to be retained on the cradle.
US09440813B2 Winding device and print winding system
The winding device has a winding shaft 205 that rewinds roll paper S conveyed from a printer 100, which has a conveyance unit 115 that conveys the roll paper S; a power input unit 206 to which power from the conveyance unit 115 is input; a winder-side power transfer mechanism that transfers power input to the power input unit 206 to the winding shaft 205; and a lever 208 that can move between a first position P1 where the lever 208 bends the conveyance path of the roll paper S from the printer 100 to the winding shaft 205, and a second position P2 where the lever 208 bends the conveyance path a shallower angle than at the first position P1, and to which is applied a force moving the lever 208 toward the first position P1.
US09440812B2 Web longitudinal position sensor
Methods and systems for determining longitudinal position of an elongated web are described. Sensors are used to detect one or more substantially continuous fiducial marks disposed longitudinally on the web. The sensors generate signals associated with the fiducial marks. A position detector receives the signals and determines a longitudinal position of the web using the sensor signals. The fiducial marks may be periodic fiducial marks, such as sine and/or cosine marks on the web and/or may be piecewise continuous marks. The coarse longitudinal position of the web can be determined based on periodically recurring features of the fiducial marks. The fine longitudinal position can be determined based on continuous portions of the fiducial marks between the periodically recurring features.
US09440810B2 Image forming apparatus and sheet tray
An image forming apparatus includes a housing, a sheet conveyance passage, a main tray, a downstream tray, and an elastic member. The main tray includes a first fastening portion and a first support portion, and is pivotable about an axis of the first support portion to thereby be openable and closeable with respect to the housing. The downstream tray includes a second fastening portion, and a second support portion disposed further inside the housing than the first support portion, the downstream tray overlapping the main tray, and being pivotable about an axis of the second support portion and thereby relatively movable with respect to the main tray. The elastic member is expandable and contractible and fastened on the first fastening portion of the main tray and the second fastening portion of the downstream tray.
US09440797B1 Conveyor chain map for a mining system
A mining system that includes a conveyor and controller. The conveyor includes a first sprocket and a second sprocket, a chain, a drive mechanism, and a sensor. The chain is associated with the first sprocket and the second sprocket and includes a plurality of chain components. The drive mechanism is coupled to the first sprocket or the second sprocket and is operable to drive the first sprocket or the second sprocket. The sensor is operable to generate a signal related to a characteristic of the conveyor. The controller is operable to receive the signal from the sensor, determine a number of chain components that have passed a datum point based on the signal, determine the location of at least one of the plurality of chain components based on the number of chain components that have passed the datum point, and update a map of the chain based on the location.
US09440792B2 Component mounting apparatus
A component mounting apparatus includes a plurality of transport conveyor units that are arranged in parallel and transports boards, each transport conveyer unit including a pair of transport rails of a fixed rail and a movable rail, a fixed side transport motor that drives a fixed side transport belt provide on the fixed rail, and a movable side transport motor that drives a movable side transport belt provide on the movable rail. The fixed side transport motor is provided on a side surface of the fixed rail that faces the movable rail, and the movable side transport motor is provided on a side surface of the movable rail that faces the fixed rail. The fixed side transport motor and the movable side transport motor are arranged so as not to interfere with each other when the distance between the pair of transport rails is changed.
US09440790B2 Inter-facility transport in inventory management and fulfillment systems
In an infrastructure that uses a mobile order fulfillment system, robotic drive units may be dispatched and instructed to bring inventory holders to a workstation where at least one of the inventory holders is packed and prepared for shipment. The robotic drive units are then instructed to move the prepared inventory holder to a transport vehicle such as a truck. Fiducial marks may be removably placed within the transport vehicle to aid navigation of the robotic drive units. At a destination facility, additional robotic drive units may be instructed to move the inventory holders from the truck and place the inventory holders at appropriate storage locations.
US09440789B2 Portotrash (portable personal garbage storage/disposal unit)
The Portotrash garbage disposal unit comprises a hollow ring forming a mouth of the garbage disposal unit. Legs capable of connecting to and supporting the mouth and allowing the unit to stand in an upright standing position are provided. A bag that fits over and is kept in place by the hollow ring is provided and occupies at least some of the space formed in between the legs. Preferably, there are four legs identified as a first leg, a second leg, a third leg, and a fourth leg. The first and the third leg are connected to each other by a first connecting member forming a first leg pair, and the second and fourth legs are connected to each other by a second connecting member, forming a second leg pair. The first leg pair and the second leg pair are pivotally connected to each other through their respective connecting members. Hollow ring comprises a clasp or other fitting mechanism corresponding to each leg to which it connects. When in a completely folded position, the first leg is in touch with the second leg and the third leg is in touch with the fourth leg. Connecting members can be in the lower or middle portion of their corresponding legs. In one embodiment, the trash bag is made of plastic with odor control properties.
US09440788B2 Waste packing system and method of use
The present invention is directed to a waste packaging system, a method of storing waste and to a film for use in this system and method.
US09440787B1 Platform for supporting and moving a bulk seed container or the like
A platform for supporting and moving a bulk seed container or the like including a horizontally disposed worker support platform frame having at least one worker support platform positioned thereon. The platform frame has a supporting structure for supporting a bulk seed container thereon. The platform frame may have a discharge chute thereon.
US09440785B2 Method of delivering, storing, unloading, and using proppant at a well site
A proppant discharge system has a container with an outlet formed at a bottom thereof and a gate slidably affixed at the outlet so as to be movable between a first position covering the outlet to second position opening the outlet, and a support structure having an actuator thereon. The container is removably positioned on the top surface of the support structure. The actuator is engageable with gate so as to move the gate from the first position to the second position. A conveyor underlies the container so as to receive proppant as discharged from the container through the outlet. The container is a ten foot ISO container.
US09440784B2 Automobile safety kit and methods of using the same
The present invention relates to an automobile safety kit and methods of using the same. Specifically, the present invention comprises safety articles contained within a rigid, resilient and easily-openable container having items therein useful for protecting automobile passengers during a flood or other natural disaster event. The kit preferably comprises a length of resilient rope having a carabineer or other connector on an end thereof, a seatbelt cutter, a window hammer for breaking an automobile window, and a pair of magnetic clamps having handles thereon for utilization by a user to remain on or in proximity to the automobile or other metal structure, especially during a flood.
US09440782B2 Plant organizing and growing assembly
A plant organizing and growing assembly includes a housing that has a bottom wall and a perimeter wall which is attached to and extends upwardly from the bottom wall. The perimeter wall has an inner surface and an outer surface. The perimeter wall bounds an enclosed space and the bottom wall has a generally rectangular shape. A plurality of legs is coupled to and extends downwardly from a bottom surface of the bottom wall. The legs are spaced apart and include four corner legs each positioned adjacent to one of the corners of the bottom wall. Each of the corner legs has a bottom surface having an aperture extending therein. Each of the apertures terminates before extending through the bottom wall such that the apertures are spaced from an upper surface of the bottom wall.
US09440773B2 Device with one-way valve
A dispenser for dispensing a substance, such as a liquid lipstick or other cosmetic, pharmaceutical or cosmeceutical product, has a body with a variable-volume storage chamber for storing the product. A dispensing portion is connected with the body and a one-way valve for dispensing amounts of product therethrough. The dispensing portion defines a compression chamber in fluid communication with the storage chamber for receiving product therefrom, and an outlet aperture coupled in fluid communication with the compression chamber. The one-way valve has a valve seat, and a visco-elastic valve cover seated on the valve seat and defining a normally-closed, axially-extending seam therebetween forming a fluid-tight seal between the valve cover and valve seat. The flexible valve cover is movable relative to the valve seat, and the seam is connectable in fluid communication with the outlet aperture to allow the passage of product through the seam and out of the dispenser. An actuator is drivingly connected to the compression chamber for pressurizing product within the compression chamber and dispensing an amount of product within the compression chamber.
US09440764B2 Method of deploying a retail ready container
A method of deploying a retail ready container from a single container blank utilizes a container having a container body portion and a protective cover portion. The container in the assembled state is configured so that the finished sides of left and right side cover panels are respectively positioned adjacent to and opposed from respective finished sides of left and right side container body panels. The container is deployed in a retail environment by lifting the protective cover portion upwardly with respect to the container body portion in a pivotal movement, at least partially tearing the frangible connections between the respective container body panels and cover panels.
US09440758B2 Inspection device for a production machine
The invention relates to an inspection device for a production machine, in particular, a bottling plant 1 with a filling device 7 or a filling and sealing device 13, with a stream of products (5) consisting of one or more columns, wherein the inspection device is arranged in the production machine, advantageously in the bottling plant 1, directly after the filling device 7 or the filling and sealing device 13 or before a separating device 23, so that the products 5 are inspected before the separation 23 or packaging 25 of the products 5. Furthermore, the invention relates to an inspection method for a production machine, in particular, for a bottling plant 1, in which an inspection device consisting of a source 17 and a sensor 19 scans several products 5 perpendicular or diagonal to the product motion B.
US09440749B1 Emergency mechanical and communication systems and methods for aircraft
A system for rapid separation of a flight data recorder from an aircraft comprises a flight data recorder; an emergency detection system comprising a plurality of sensors for detecting flight parameters and at least one computer processor for analyzing the flight parameters and determining, based on the analysis, that an emergency event is occurring; a rapid ejection system comprising a pneumatic system configured to eject the flight data recorder out of an opening in a housing and through the skin of the aircraft when the emergency detection system determines that the emergency event is occurring; and a soft landing system, said soft landing system being attached to the flight data recorder and configured to reduce force of impact upon landing and increase buoyancy of the flight data recorder.
US09440748B1 Notification management systems and methods of notifying an aircraft crew member using the same
A method of notifying an aircraft crew member using a notification management system includes creating a rule based on at least one flight condition and transmitting the created rule to the aircraft. The at least one flight condition may include air travel data. The method also includes receiving aircraft data generated by one or more aircraft systems, comparing the received aircraft data with the rule, and issuing a notification to the aircraft crew member based on the comparison between the received aircraft data and the at least one condition in the rule. The notification may include at least one action to be performed in response to the notification.
US09440746B2 Aircraft vapour trail control system
An aircraft propulsion control system for an aircraft having a plurality of combustion engines is provided. The system has a plurality of sensors for sensing a condition indicative of properties and/or formation of vapor trails which may be formed by the plurality of engines. A controller is arranged to control one or more operational variable for each of the plurality of engines. The controller is arranged to undertake a search of trial values of the operational variable by instructing different concurrent values of said operational variable across the plurality of engines and determining the resulting impact on the vapor trail formation and/or properties as sensed by the sensors. A population-based search may be performed, for example in parallel over all the engines at once so as to reduce the time taken to achieve vapor trail mitigation.
US09440738B2 Dry lubricated rotary actuator for in blade rotor control
A rotor blade assembly includes a rotor blade, a rotatable flap portion disposed along a span of the rotor blade. A rotary actuator is located inside the rotor blade and is operably connected to the flap portion to rotate the flap portion about a flap axis. A rotary-winged aircraft includes an airframe and a main rotor assembly operably connected to the airframe. The main rotor assembly includes a plurality of rotor blade assemblies rotatable about a rotor assembly axis. At least one rotor blade assembly of the plurality of rotor blade assemblies includes a rotor blade and a rotatable flap portion disposed along a span of the rotor blade. A rotary actuator located inside the rotor blade and is operably connected to the flap portion to rotate the flap portion about a flap axis. The rotary actuator is absent oil, grease or other fluid lubricant.
US09440736B2 Special personal electric helicopter device with integral wind turbine recharging capability
Disclosed is a Personal Electric Helicopter device with an integral wind turbine recharging capability. The device is a relatively small, lighter weight powered aircraft capable of vertical take-offs and propulsion across various terrain at low altitudes. The device is uniquely capable of re-charging its power source by connection to an electrical grid or by using its uplift components as a wind turbine for re-charging. The preferred embodiment is comprised of a rechargeable uplift and propulsion power system with components and features; a frame structure to carry an operator and/or payload; a means to connect the structure to the power system; and a means to control the uplift and propulsion system wherein the vehicle may be used to elevate and propel a payload at low altitudes across various terrains and may be positioned to reverse power the wind turbine to recharge the batteries.
US09440732B2 Spring assembly for aircraft components
A spring assembly elongate along a longitudinal direction includes a first spring that includes a first spring member and a first elongate member that extends from the first spring member along the longitudinal direction. The spring assembly includes a second spring including a second spring member and a second elongate member that extends from the second spring member along the longitudinal direction. The second elongate member extends through the first spring member, and the first elongate member extends through the second spring member such that the first and second spring members are spaced apart with respect to each other along the longitudinal direction.
US09440730B2 Latching apparatus and methods
Latching apparatus and methods are disclosed herein. An example apparatus includes a first latch portion including a first tooth and a first pin disposed in a first aperture defined by the first tooth and a second latch portion including a second tooth and a second pin disposed in an second aperture defined by the second tooth. The second tooth of the second latch portion is to mesh with the first tooth of the first latch portion to substantially orient the first pin and the second pin along an axis. The example apparatus further includes an actuator adjacent a first end of one of the first latch portion or the second latch portion to move the first pin and the second pin along the axis to lock the first latch portion to the second latch portion.
US09440727B2 Telescoping aircraft panel door
A telescoping aircraft door is disclosed having first and second panels that slide relative to one another to extend and retract as the door closes and opens, respectively. The first panel is hinged to the door frame in a traditional manner, and the second panel is fixed to the door frame by a linkage that limits the arc of the second panel. By selecting the location and length of the linkage, the relative movement of the two panels can be predictably controlled to reduce the depth of the door when closed and the length of the door when opened.
US09440720B1 Tommy power paddle
A paddle device, where this principle described may be configured to accommodate canoe, kayak, paddle boards or any similar watercraft using a paddle type device. This paddle device comprises a shaft having a first end and a second end with a paddle-like blade having a proximal end and a distal end and coupled to the second end of the shaft. This paddle blade device is equipped with one or more multi-blade propellers that are mounted on the paddle blade. The multi-blade propeller or multi-blade propellers are driven by the pulling motion of the paddler or driven by the action of the natural water current the paddler is navigating. The propeller is designed to swivel so as to keep the propeller blade more in direct alignment with the force of the water driving it. This insures that the propeller is at the most efficient angle to help propel and control the watercraft. The propeller or propellers are protected with a lattice type guard on both sides of the paddle blade.This paddle blade is also equipped with orifices devices through the paddle blade that have a center cone like shape. The larger orifice opening is on the pulling side of the paddle blade and the smaller water discharging orifice is on the opposite side. These orifice devices are made with a center rotating cone shape that has inner ribs and grooves and mounted in the orifice housing. This device also has a capability for the center rotating cone shape to swivel so as to keep the generated water force more in direct alignment with the force of the water driving it. In this manner the force of the water is increased through the paddle blade to give the water increased pressure to help propel the watercraft device the paddler is navigating. This force also lessens the amount of force required to pull the paddle through the water. The orifice rotating device is also protected with a lattice type guard on both sides of the paddle blade.This paddle device can also be used in a reverse fashion by rotating the paddle blade 180 degrees so as to be used when navigating a watercraft with the water current in order to help stabilize the watercraft by using the force of the current against the propeller blades and the energy generated by the orifices to aid in controlling the watercraft.
US09440719B2 Magnus rotor
Various embodiments provide a Magnus rotor having a carrier arranged in the interior of the Magnus rotor, a rotor which rotates about the carrier in operation of the Magnus rotor, a plate which horizontally closes off the rotor, and a bearing which carries the rotor on the carrier. The rotor has at least one opening in the plate. The carrier has at least one fixing point for lifting the Magnus rotor by means of at least one fixing means and a lifting apparatus.
US09440718B1 System and methods of using unmanned underwater vehicles (UUVs) along with tethers and tethered devices
The present invention comprises a plurality of UUVs, tethers and tethered devices. The devices that are tethered comprise explosive devices or acoustic devices. The UUV provides mobility and controllability for the tethers and the tethered devices. The tether is also used as a means to entangle target vessel's propeller. The entangled propeller's revolution moves the explosive device closer to the target vessel for denotation. The tether is made with high strength material whereby once entangled, it is difficult for the propeller itself or intervention to disentangle. The system has a detachable housing with fluid dynamic shape. The whole system is designed to submerge during operation. The system can be wirelessly controlled by a remote command center via satellite link, or by a nearby command center directly.
US09440717B2 Hull robot
A hull cleaning robot includes at least one cleaning apparatus for cleaning the hull of a vessel, at least one drive track holding the robot on the hull as the robot maneuvers about the hull, and at least one turbine actuatable by water flowing past the hull for operating the at least one drive track and, optionally, the cleaning apparatus.
US09440716B1 Enhanced system and method for automatically deploying boat fenders
A system for automatically deploying boat fenders, comprising a basket for lowering fenders, said fender attached to a line, said line coupled to a winch, said winch coupled to a motor, and said motor controlled by a controller, said controller being activated via a wire line or wireless control signals, wherein a computing device with a software is used to control one or more controllers of the baskets.
US09440714B2 Forward propelled hover board
A forward water propelled hover board comprising a rigid board having greater length than width. The rigid board having a rear end with a high pressure water outlet nozzle and a central pipe connecting a water hose inlet, wherein the outlet nozzle when fed with a high pressure water source from the water hose inlet provides a forward thrust to the water propelled hover board.
US09440711B2 Self-securing, vertically mounted marine anchor stowage device and method of use thereof
A self-securing, vertically mounted marine anchor stowage device may comprise a bracket, forming a generally U-shaped channel and having an alignment guide designed and configured to capture the shaft of a marine anchor, a plurality of mounting slots which, in coordination with mounting hardware such as U-bolts, washers and nuts, enable the anchor stowage device to be mounted to a vessel, and a plurality of adjustment slots which, in coordination with bolt, washer and wing nut combinations, provides a means of adjustably mounting one or more rollers within the U-shaped channel, the bolts forming axes about which the rollers may rotate, the anchor stowage device being designed and configured to accommodate vertical stowage of an anchor by capturing the shaft of the anchor between the bracket and the one or more rollers, the anchor being held in the stowed condition solely by the force of gravity.
US09440709B1 Vessel and shelter assembly
A vessel and shelter assembly system that quickly converts a low profile boat into a floating teepee/tent that is capable of multiple functions and can enable a boater/passenger to spend multiple days/nights out on protected waters, marsh, or swamp without limiting the functions of the boat.
US09440703B2 Clamp assembly for fixing handlebar grip
A clamp assembly is provided for fixing a handlebar grip to a handlebar. The clamp assembly has a fixing member that is configured to be mounted on the handlebar. The fixing member has at least one mating grip locking structure and a component attachment structure.
US09440698B2 Foldable motorized scooter
The disclosure is directed to a foldable motorized scooter having at least one front wheel and at least one rear wheel, configured to operate between an extended rideable position where the front wheel and the rear wheel are aligned along a longitudinal axis, and a folded stowed position wherein the at least one front wheel and the at least one rear wheel are concentrically parallel to each other along a transverse axis, the foldable motorized scooter equipped with a rechargeable power source.
US09440697B1 Motorcycle front structure
A motorcycle includes a front fender for covering above a front wheel and a headlamp device positioned forwardly of a handlebar. At a portion of an upper surface of the front fender forwardly of the headlamp device, a recess is formed which is depressed downwardly and extends in a forward and rearward direction. A projection protruding upwardly towards the rear is formed in an intermediate portion of a rear half portion of the recess with respect to a motorcycle widthwise direction. The headlamp device has a lower end formed with a recessed area in which the projection is engageable.
US09440693B2 Air-hardenable bainitic steel part
A method of producing a forged steel part is disclosed. The method includes providing a steel billet that can be selectively hardened to different hardness levels by varying the air cooling rate. The method also includes heating the steel billet to an austenization temperature of the steel billet. The method further includes hot forging the steel billet to form the steel part including a first region and a second region. The method yet further includes selectively cooling the hot forged steel part by air cooling the first region at a first cooling rate and air cooling the second region at a second cooling rate that is less than the first cooling rate.
US09440692B2 Pin assembly for a tracked work vehicle suspension system
An undercarriage for a tracked work vehicle is provided that includes a roller wheel beam. The roller wheel beam includes a clevis having a first arm and a second arm. Additionally, the first arm includes a first opening, and the second arm includes a second opening. The undercarriage further includes a bushing mount which has a third opening and is configured to be disposed between the first arm and the second arm. Also, the undercarriage includes a pin assembly configured to couple the roller wheel beam to the bushing mount. Moreover, the pin assembly includes a first pin configured to be inserted into the first opening and a first end of the third opening. The pin assembly also includes a second pin configured to be inserted into the second opening and a second end of the third opening. Furthermore, the first pin is configured to abut the second pin when the first pin and the second pin are inserted into respective openings.
US09440680B2 Vehicle cowl structure
There is provided a vehicle cowl structure including: a cowl main body section that forms an S-shaped cross-section configured from an upper side curved portion a lower side curved portion curving, and in which an upper portion extending from the upper side curved portion toward the vehicle front-rear direction rear side is joined to a lower face of a lower end portion of a front windshield, and a lower portion is joined to a dash panel; and a front side reinforcement member that curves to as to bulge out toward the vehicle front-rear direction front side, in which an upper end portion is joined to a location between the upper side curved portion and the lower side curved portion, and a lower end portion is joined to a location between the lower side curved portion and the lower portion joined to the dash panel.
US09440679B2 Lightweight roof for vehicle
A roof for a vehicle is provided that includes a roof frame and a reinforcement frame that is disposed on an upper part of the roof frame, shaped to correspond to an upper surface of the roof frame, and provided with a bush unit formed integrally with a bolting mechanism, respectively, to be connected to the roof frame. In addition, a reinforcement fiber tow is processed to correspond to a shape of the roof frame through the bush unit. A roof panel that is formed as a plate shape to cover the roof frame is disposed at an upper end of the reinforcement frame to be connected thereto.
US09440676B1 Tie rod assembly with integrated safety tip
Disclosed is a tie rod having a threaded shaft at a proximal end and a body at a distal end. The body has a spherically expanded, substantially empty interior and having a truncated top and a truncated bottom. Each truncated top and bottom having a hole wherein the holes are in alignment transverse to the longitudinal extent of the tie rod. A tie rod pin has a distal end that extends through the truncated bottom body hole and terminated with a threaded distal end, an intermediate spherical section movably nested within the spherically expanded truncated tie rod body, and a distal end that extends from the spherical section through the truncated top body hole and being terminated with a plate being larger in diameter than the hole that penetrates the upper truncated body so that the tie rod pin is restrained from pulling through the tie rod body.
US09440674B2 Methods, systems and apparatus for steering wheel vibration reduction in electric power steering systems
Methods, system and apparatus are provided for reducing steering wheel vibrations (SWVs). At least one heterodyning operation is performed during the generation of a gain-and-phase-compensated motor drive command signal. The gain-and-phase-compensated motor drive command signal is generated at a particular angular frequency, based on an angular velocity and an angular position of a wheel. The gain-and-phase-compensated motor drive command signal is communicated to an electric power steering system to control motor torque to reduce periodic content in a periodic electrical torque signal at the particular angular frequency.
US09440672B2 Electric power steering assembly
A rack drive assembly adapted for use in a vehicle electric power steering assembly includes a ball nut assembly having at least a first end portion and an opposite second end portion, a bearing assembly carried by the ball nut assembly for rotatably supporting the ball nut assembly, a pulley assembly configured to be carried by the ball nut assembly, and at least a first spanner nut configured to be carried by the first end portion of the ball nut for securing the bearing assembly on the ball nut assembly. The ball nut includes a flange provided on an outer portion thereof configured to connect the ball nut to a pulley of a pulley assembly for rotation therewith. The flange is spaced remote from an end of the second end portion of the ball nut.
US09440670B2 Bracket for support structure for steering column, and support structure for steering column
A bracket is used in a support structure for a steering column. The support structure includes an instrument panel reinforcement, a steering support bracket, and a floor brace. In one aspect, the bracket includes a first portion and a second portion, which are configured to be arranged spanning between the steering support bracket and the floor brace. The first portion is arranged between the steering support bracket and the floor brace at a first angle with respect to horizontality. The second portion is arranged between the steering support bracket and the floor brace at a second angle, which is different from the first angle.
US09440669B2 Stroller
A stroller assembly is provided that includes a frame. The stroller assembly may also include a plurality of wheel assemblies that are operable to mount to the frame. In addition, the stroller assembly may include a front seat module and a back seat module comprised of a plastic material. The front seat module and the back seat module may include integral fastener members that are operative to engage with each other when the front seat module and the back seat module are mounted to the frame.
US09440665B2 Top of rail foam bar
A rail applicator assembly includes a rail having a head portion, a base portion, and a web portion extending between the head portion and the base portion. The head portion defines an outer surface. An applicator for applying a friction modifying material to the surface of the rail includes a foam body and an applicator support. The foam body is secured to the applicator support and defines a flow passageway that extends through the foam body for friction modifying material to flow through.
US09440661B2 Integrated ceiling assembly for railcars
A ceiling assembly for a vehicle includes a plurality of supporting elements for fastening components, and a plurality of connecting elements connecting the supporting elements. The plurality of connecting elements is integrally designed with the plurality of the supporting elements forming an integrated ceiling assembly. Further, a vehicle and a method for manufacturing a ceiling assembly to a ceiling of a vehicle are disclosed.
US09440660B2 Method for remote communication with and through a vehicle
A system for a vehicle includes an interactive display subsystem operable to generate output for display on a vehicle window, the output associated with a two-way communication interface for remote communication with a user input subsystem. A method of operating a system for a vehicle includes displaying a two-way communication interface on a vehicle window for remote communication with a user input subsystem.
US09440659B2 Driver advice system for a vehicle
A driver advice system for a vehicle having at least one vehicle subsystem comprises a selector for receiving at least one driving condition indicator for the vehicle and for selecting, from a plurality of settings, a preferred setting for the at least one vehicle subsystem in response to the at least one driving condition indicator. The driver advice system includes an indication device for providing to the driver an indication of the preferred setting for one or more of the vehicle subsystems.
US09440658B2 System and method for controlling an automobile using eye gaze data
A system or method capable of using automobile camera system data to generate biometric information for the use in identifying authorized drivers and customizing and controlling automobile components. The system is versatile enough to distinguish between a new or unauthorized person in the automobile and respond accordingly.
US09440657B1 Advanced vehicle operator intelligence system
The method, system, and computer-readable medium cause the monitoring of a vehicle operator during the course of vehicle operation to determine whether the vehicle operator is impaired and causes a mitigating response when an impairment is determined to exist. The vehicle operator, the environment surrounding the vehicle, or forces acting on the vehicle may be monitored using a variety of sensors, including optical sensors, accelerometers, or biometric sensors (e.g., skin conductivity, heart rate, or voice modulation). When the vehicle operator is determined to be impaired, an alert or other mitigating response is implemented, based on the sensor data. In some embodiments, mitigating actions may be taken to avoid vehicle operator impairment. In further embodiments, a training period may be used to generate a profile for the vehicle operator.
US09440655B2 Method of selecting modes of operation for a hybrid vehicle
A method for enabling a user of a hybrid vehicle to assign different modes of operation to different segments of a particular route instead of, for example, simply operating the vehicle in an electric mode until its battery is depleted and then switching to an engine or charge-sustaining mode. This method may be useful in situations where a plug-in hybrid electric vehicle (PHEV) is being frequently driven on a particular route whose distance exceeds the PHEV's electric mode range. The customized route, complete with operating mode selections for certain route segments, can be stored at the vehicle and automatically implemented when the vehicle recognizes the stored route. Other potential features include evaluating the route after it has been developed and/or driven and providing the user with some feedback so that they can make it more efficient.
US09440646B2 System and method for responding to driver behavior
Methods of assessing driver behavior include monitoring vehicle systems and driver monitoring systems to accommodate for a driver's slow reaction time, attention lapse and/or alertness. When it is determined that a driver is drowsy, for example, the response system may modify the operation of one or more vehicle systems. The systems that may be modified include: visual devices, audio devices, tactile devices, antilock brake systems, automatic brake prefill systems, brake assist systems, auto cruise control systems, electronic stability control systems, collision warning systems, lane keep assist systems, blind spot indicator systems, electronic pretensioning systems and climate control systems.
US09440642B2 Drive system for hybrid vehicle
A drive system for a hybrid vehicle includes a planetary gear unit, a first rotating machine connected to a sun gear of the planetary gear unit, an engine connected to a carrier of the planetary gear unit, a second rotating machine and drive wheels connected to a ring gear of the planetary gear unit, a regulating mechanism that regulates rotation of the carrier, a first running mode in which the vehicle runs using the second rotating machine as a power source, and a second running mode in which the vehicle runs using the first rotating machine and the second rotating machine as power sources while the regulating mechanism regulates rotation of the carrier. The carrier is rotated by the first rotating machine when the vehicle shifts from the first running mode to the second running mode.
US09440635B2 System and method of speed-based downspeed coasting management
A velocity profile can be used in conjunction with vehicle operating condition data to determine a gear shift schedule that mitigates the amount of service brake effort required to slow a vehicle by making optimal use of engine speed, friction and engine brakes. The gear shift point drives the engine to a higher operating speed and greater frictional torque, slowing the vehicle, which can then coast to a desired speed. The gear shift point can be timed to minimize fuel consumption during the maneuver. Thus, a vehicle downshift event is created based on the transmission gear recommendation. The benefit is increased freight efficiency in transporting cargo from source to destination by minimizing fuel consumption and maintaining drivability.
US09440634B2 Control device for vehicle and method of controlling vehicle
A control device for a vehicle includes a control unit configured to: implement a first travelling mode of engaging a power connecting/disconnecting device at a time an accelerator opening is greater than a fully closed state and not greater than a first opening; implement a second travelling mode of releasing the power connecting/disconnecting device at a time the accelerator opening is greater than the first opening and smaller than a second opening; implement a third travelling mode of stopping a fuel supply to an engine with the power connecting/disconnecting device engaged at a time the accelerator opening is fully closed; and control an output of the engine so that a vehicle deceleration at a time of implementing the first travelling mode gradually changes.
US09440630B2 Pneumatic brake distributor valve assembly for a rail vehicle
A pneumatic brake valve unit for a rail vehicle, includes: a main device (20) that selectively controls a communication path between a brake pipe connector (18) and either an atmospheric exhaust line (19) or an auxiliary reservoir connector (16), such that the pressure at the brake pipe connector (18) is k times the difference between the pressure at a control reservoir connector (14) and the pressure at a main brake pipe connector (12), k being a proportionality factor; a cut-off valve (21) that controls a communication path between the main brake pipe connector (12) and the control reservoir connector (14); an accelerator device (22) that controls a communication path between the main brake pipe connector (12) and an air discharge member (19); and a driving pilot (39) which is common to both the valve (21) and the accelerator device (22) and which controls their respective communication paths.
US09440628B2 Brake device for vehicle
A brake device for a vehicle includes: a cylinder body in which brake oil is compressed; a first piston pressurizing brake oil while moving along the inside of the cylinder body; a connection part having a smaller outer diameter than the first piston, and including one side connected to the first piston and the other side extended to the outside of the cylinder body; a pipe line part connecting the cylinder body and a wheel brake, and transferring the brake oil compressed through the movement of the connection part to the wheel brake; and a valve controlling the flow of the brake oil transferred along the pipe line part.
US09440625B2 Parking lock arrangement and motor vehicle transmission
A parking lock arrangement for a motor vehicle transmission has a blocking arrangement actuatable between a release position and a blocking position. The blocking arrangement is designed to immobilize a motor vehicle in the blocking position. The parking lock arrangement has an arrangement for actuating the blocking arrangement. The actuating arrangement has a cam disc supported on a housing and driveable for rotation and has an actuating cam portion that extends over a first circumferential region of the cam disc that is greater than 5° and less than 180°. The actuating arrangement has a lever supported pivotably on the housing and coupled to the blocking arrangement. The lever is connected to a driving feature that is coupled to the cam disc, such that, when the cam disc is rotated, the driving feature is taken along by the actuating cam portion in such a way that the lever is pivoted in order to actuate the blocking arrangement.
US09440619B2 Steering lock device
A steering lock device includes a lock bolt configured to correspond to rotation of a key cylinder and to unlock a steering shaft, and an ignition switch configured to correspond to the rotation of the key cylinder and to perform switch operation. In the steering lock device, the lock bolt is provided to a rear side of a body in a direction of a body side orthogonal to a rotation axis of the key cylinder. Also, the ignition switch includes a first switch and a second switch and is arranged to a side part of the body in a direction different from the forward movement direction of the lock bolt. The first switch is configured as the ignition switch and the second switch is configured as a key detection switch.
US09440618B2 Vehicle opening monitoring device
A vehicle opening monitoring device for monitors and indicates the presence of unclosed openings of a vehicle when the vehicle is being locked. The device includes a vehicle having a plurality of openings. Each of the openings has a closed position and an open position. A vehicle locking assembly is coupled to the vehicle for locking doors of the vehicle. Each of a plurality of monitors detects when an associated one of the openings is in the closed position. Each monitor is communicatively coupled to a processor operationally coupled to the vehicle locking assembly. The processor allows locking of the vehicle locking assembly when the monitors detect all the openings are in the closed position.
US09440615B2 Initiator assemblies
An initiator assembly for placement in an associated opening in an initiator-containing device includes an initiator device having at least one igniter element and an elastomeric overmoulding. The initiator device includes at least one of a thermoplastic initiator base and a thermoplastic adapter integrally joined to a base of the initiator-containing device. The elastomeric overmoulding is integral with at least one structural component such as the initiator base, the adapter and the base of the initiator-containing device. The elastomeric overmoulding serves to sealingly mate the initiator assembly in an initiator-accepting opening in the initiator-containing device. Also provided are corresponding methods of making an initiator assembly.
US09440612B2 Dual-chambered passenger airbag
An airbag includes an outer shell defining an interior, at least one vent opening structured to enable fluid communication between the interior and an exterior of the airbag, and a divider dividing the airbag interior into an upper chamber and a lower chamber. The divider is deflectable in a first direction toward the lower chamber and in a second direction toward the upper chamber. A vent cover is coupled to the at least one vent opening and to the divider so as to close over and restrict a flow of gas through the at least one vent opening when the divider is deflected in the first direction, and so as to permit the vent cover to open so as to enable an unobstructed flow of gas through the at least one vent opening when the divider is deflected in the second direction.
US09440611B2 Gas bag arrangement for a vehicle occupant restraint system
A gas hag arrangement for a vehicle occupant restraint system comprises an inflatable gas hag, wherein the gas bag includes at least one vent device for venting gas from the gas bag, wherein the vent device in a first condition has a first outflow cross-section and in a second condition a second outflow cross-section; as well as a release mechanism which initially fixes the vent device and which releases the same after activation. The release mechanism includes an element to be filled with gas, with which the vent device is connected such that before filling of the tillable element it is fixed at the same and during filling of the fillable element is detached from the same, wherein the vent device is directly or indirectly connected with the tillable element via a releasable connection which will tear during filling of the fillable element and release the vent device.
US09440610B2 Curtain airbag apparatus
Provided is a curtain airbag apparatus that prevents a head of an occupant from being moved forward. To this end, according to the curtain airbag apparatus according to the exemplary embodiment of the present invention, an auxiliary airbag is installed on an outer surface of a curtain airbag in order to prevent the head of the occupant from being moved forward.
US09440609B2 Airbag module and module housing
A housing for an airbag module includes an extrusion incorporating a body portion and a cover extruded integrally with the body portion so as to form a single monolithic unit.
US09440608B2 Seat occupant determining apparatus
A seat passenger determination apparatus includes: a first determination processing unit configured to determine a passenger is not seated on a vehicle seat by having gotten out of the vehicle and transfer the mode to a not-seated recognition mode when a load variation width detected by a load detection apparatus falls within a first threshold value in a state in which a non-fastened state of a seatbelt is detected; and a second determination processing unit configured to determine the passenger is not seated on the vehicle seat by having gotten out of the vehicle and transfer the mode to the not-seated recognition mode when the load variation width detected by the load detection apparatus falls within a second threshold value which is larger than the first threshold value during a predetermined time when the fact that the seatbelt has changed from the fastened state to the non-fastened state is detected.
US09440607B1 Energy diverting bumper structures for bumpers and methods of connecting energy diverting bumper structures
A bumper includes a bumper reinforcement beam and a reinforcement bracket positioned on a front side of the bumper reinforcement beam at an outboard end of the bumper reinforcement beam. An energy diverting bumper structure is positioned on a front side of the reinforcement bracket. The energy diverting bumper structure is connected directly to the reinforcement bracket and is connected indirectly to the bumper reinforcement beam through the reinforcement bracket.
US09440605B2 Configurable rental vehicle
A rental vehicle has features that can be activated or deactivated wirelessly. Additional features can be purchased and activated after a customer has paid for an initial set of features and started to use the vehicle. Configuration of the vehicle is automated by transmitting a configuration message to the vehicle.
US09440603B2 Location sensitive learning interface
A vehicle control system is provided that is able to (i) identify a particular driver from other potential drivers and (ii) monitor various vehicle functions in order to determine if the identified driver repeatedly performs the same behavior when the vehicle is at or near the same location. When the control system determines that the identified driver repeats the same behavior in response to the vehicle being at or near the same location, the controller learns that behavior and associates it with the identified driver so that it can be automatically performed, without driver interaction, when the vehicle is at or near the same location in the future.
US09440600B2 Fail operational power system with multiple energy storage devices
Method for operating a fail operational power system for a vehicle includes monitoring voltages on first and second power distribution paths arranged in parallel. Each path includes a respective first or second isolator switch effective when operative in a closed state to power the respective path by a respective energy storage device for supplying electrical power to one or more loads partitioned on each of the paths. A third isolator switch controllably operative between open and closed states is monitored. The closed state of the third isolator switch connects the paths and the open state opens the connection between the paths. When a predetermined operating mode requiring fail operational power is enabled, the third isolator switch is controlled to the open state when at least one of the monitored voltages violates a reference voltage and is controlled to the closed state when neither one of the monitored voltages violate the reference voltage.
US09440595B2 Instrument panel substrate with pin positioning pattern for correct placement of multiple ECU attachments
A panel-ECU bracket attachment system that prevents the placement of an ECU at an incorrect location within a motor vehicle. The panel-ECU bracket attachment system includes a panel, e.g. an instrument panel, with a first ECU bracket attachment site and a second ECU bracket attachment site. The first ECU bracket attachment site has a first pair of alignment pins spaced apart by a first distance therebetween and the second ECU bracket attachment site has a second pair of alignment pins spaced apart by a second distance therebetween. The second distance is not equal to the first distance. The instrument panel-ECU bracket attachment system also includes a first ECU bracket with a first pair of pin apertures that are spaced apart from each other by the first distance and a second ECU bracket with a second pair of pin apertures that are spaced apart from each other by the second distance.
US09440593B2 Vehicle mounting structure for electronic device
The vehicle mounting structure comprises an electronic device, a first bracket, a drive train and a first vibration isolating bush. The electronic device is fixed on the drive train via the first bracket, and the electronic device and the drive train define a gap therebetween. The first vibration isolating bush is provided between the first bracket and the electronic device.
US09440586B2 Multi-camera vision system for a vehicle
A multi-camera vision system for a vehicle includes a rear-mounted video camera, a front-mounted video camera, and first and second side-mounted video cameras at respective sides of the vehicle. Captured image data is processed at a central data processor to generate video images for display on a video screen. The captured image data is processed at the central data processor in order to detect objects that are within the combined field of view of the video cameras. At least one non-visual sensor captures sensor data in a region external of the vehicle and the captured sensor data is provided to the central data processor. An alert to the driver of the equipped vehicle is generated when, via processing at the central data processor of at least one of received image data and received sensor data, a potential hazard is determined to exist.
US09440584B2 Photoluminescent vehicle console
A vehicle illumination apparatus is disclosed. The vehicle illumination apparatus comprises a console rotatably connected to a portion of a seat. The console is operable to rotate from a first position to a second position. A light source is disposed proximate the console and configured to emit a first emission of light. The illumination apparatus further comprises at least one light guide configured to direct the first emission to a first photoluminescent portion disposed on the console when the console is oriented in the first position.
US09440581B2 Navigation system activation of a vehicular directional signal
Devices, methods and systems describe a turn signal activation system. As the navigation system determines that the vehicle is approaching a turn or other operation, the turn signal may be automatically activated in the appropriate direction (e.g., right-turn signal for a right turn, and a left-turn signal for a left turn). Once the navigation system determines that it is appropriate to deactivate the turn signal, the turn signal may be automatically deactivated. In this fashion, other drivers on the road may be able to anticipate the actions of the vehicle based on the activation and deactivation of the turn signals, and thereby prevent accidents from occurring.
US09440580B2 Optic assembly having virtual external common focus
An optic assembly has a reflector with a reflective surface, one or more light sources, and a mask with one or more apertures. Facets on the reflective surface direct light rays so that a substantial portion of the light rays within the optic assembly can be managed as if they were emitted from a focal point located outside the optic assembly.
US09440579B2 Photoluminescent step handle
A vehicle illumination apparatus is disclosed. The illumination apparatus comprises a retractable handle having a proximal end portion in connection with a tailgate. The retractable handle forms an internal passage therethrough from the proximal end portion to a distal end portion of the retractable handle. A light source is disposed proximate the proximal end portion and configured to emit a first emission through the internal passage. At least one light emitting portion is disposed along a length of the retractable handle and configured to output light derived from the first emission to an outside environment.
US09440577B2 Vehicle wrecker with improved controls
A wrecker-type recovery vehicle for recovering other, disabled vehicles, and a method for doing so, which may use a CAN Bus, and which may employ wrecker controls located a distance from a side surface of the vehicle exterior. Traveler rollers may be used to facilitate longitudinal movement of a travel base assembly supporting the boom, relative to the vehicle frame.
US09440573B1 Cup holder assemblies
A cup holder assembly includes a pair of planar bodies each defining a rim, and a pair of fabric pouches that are each attached to one of the rims. The planar bodies are pivotably attached to each other and are configured such that, in a folded position, the rims are stacked and the fabric pouches are nested within each other, and in a deployed position, the rims and fabric pouches are side-by-side.
US09440566B2 Lightweight acoustic enclosures
The technology described in this document can be embodied in an acoustic enclosure for a speaker system disposed in a portion of a vehicle seat. The acoustic enclosure includes a rigid plate configured to be attached to a frame, a first section, and a second section. The rigid plate configured to support a speaker disposed in part within the acoustic enclosure. The first section is constructed from expanded resin, and disposed in contact with the rigid plate. The second section is disposed in contact with the first section, between the second section and the rigid plate. The first and second section together define a housing of the acoustic enclosure that includes at least one cavity configured to accommodate a portion of the speaker.
US09440563B2 Occupant support system
Human support systems for one or more of the safety, convenience, comfort of the user.
US09440561B2 Recliner
A recliner includes a first and second connecting members assembled together, and a ring member that holds the assembled connecting members. A dowel fitted in a fitting portion of a frame is formed in a region of an axially outer surface of the second connecting member. A radially outer portion of the second connecting member has an expanded portion expanding radially outward in a region at a circumferential position where the dowel is formed, and a recessed portion recessed radially inward in a region at a circumferential position where the dowel is not formed. A joint portion of the ring member is placed on an outer circumferential surface of the recessed portion, and the expanded portion is placed, from an inside in the axial direction, against a weld zone of the frame in which the dowel is welded.
US09440558B2 Hinge mechanism for a vehicle seat and method for operating a vehicle seat
A hinge mechanism for a vehicle seat includes an actuating lever, a disengaging lever, a main rotary axis, a deflection lever and a deflection rod. It also includes a separate first operating element for folding a backrest over in the direction of a seat part in the case of a fixed seat part, and a separate second operating element for folding over the backrest in the case of a simultaneous or subsequent pivot movement of the seat part. A method is provided for operation of a vehicle seat with a hinge mechanism.
US09440555B2 Battery pack thermal management
An exemplary assembly includes a blend structure moveable between a first position and a second position. The blend structure in the first position permits a first flow of air. The blend structure in the second position permits a second flow of air. The first flow includes more air that has moved through an engine compartment of an electrified vehicle than the second flow.
US09440554B1 Power management in electric vehicles
Various techniques described herein relate to electric vehicle power management system for managing a plurality of battery modules in a battery pack. Such electric vehicle power management system may include a plurality of battery management systems corresponding to a plurality of battery modules, and an energy management system for managing the plurality of battery management systems. The energy management system and the plurality of battery management systems may adopt master-slave wireless communication, and may use a single wireless frequency channel or a plurality of assigned wireless frequency channels.
US09440553B2 Energy management method for a vehicle and energy management device
An energy management method for a vehicle having an energy store and consumers, in which the energy reserve in the energy store is detected and a predicted actual range of the vehicle is calculated, a graphic object which visualizes the predicted actual range is generated and displayed, a user input is detected with which a setpoint range is set in that the graphic object is changed by an input device, after the setting of the setpoint range, on the basis of the difference between the setpoint range and the predicted actual range it is calculated by which changes in state of at least one subset of the consumers the setpoint range can be achieved, and the calculated changes in state are output as a proposal. Also disclosed is an energy management device for carrying out this energy management method.
US09440550B2 Battery use optimization utilizing a reserve fleet
A system for the management of a fleet of battery powered vehicles using a paradigm of a reserve pool of vehicles as opposed to a reserve fleet of batteries. In this system, a reserve pool of vehicles is always maintained in a ready state such that vehicles being returned with depleted batteries may be replaced with a vehicle having a fully-charged battery. The system maintains a balance between reserve fleet size and charging time (and therefore the life of the batteries) to provide optimal performance and cost savings. The system has the added advantages of capital efficiency in that that the time and labor required to change batteries, and the need to maintain extra batteries is eliminated.
US09440549B2 System and method for detecting vehicle proximity in an electrical vehicle supply equipment
A system and method is provided for detecting vehicle proximity in an electric vehicle supply equipment (EVSE). A sensor may be configured to detect a presence of a vehicle within a predetermined distance of the EVSE. A processor may be configured to determine that the vehicle is in proximity of the EVSE in response to the sensor detecting the presence of the vehicle. The processor may be further configured to generate an alert in response to a determination that the vehicle is in proximity of the EVSE.
US09440548B2 Method and system for managing and controlling electrical vehicle charging events
A system and method for managing and controlling charging of electric vehicles via charging stations over an advanced metering infrastructure is provided. Smart meters are deployed in the charging stations. Electric vehicle clusters which are logical representations of at least the charging stations are created. Policies for controlling electric vehicle charging based on data obtained using the electric vehicle clusters are generated. Further, it is analyzed if meter data obtained from the smart meters using the electric vehicle clusters comply with the generated policies. The meter data is obtained using the electric vehicle clusters identified with electric vehicle charging events. Policy violation action data is generated by applying predetermined rules if it is determined that the policies are violated. The policy violation action data is then sent to the identified electric vehicle clusters for controlling electric vehicle charging.
US09440533B2 Control apparatus for a vehicular 4-wheel drive system
A control apparatus for a vehicular 4-wheel drive system provided with: primary drive wheels to which a drive force is transmitted from a drive power source; auxiliary drive wheels to which the drive force is selectively transmitted; a first clutch configured to selectively place a first power transmitting path in a power transmitting state and a power cutoff state; and a second clutch disposed in a second power transmitting path to selectively place the second power transmitting path in a power transmitting state and a power cutoff state. The first and second clutches are placed in fully released states to establish a 2-wheel drive mode. The control apparatus includes a first-clutch control portion configured to bring the first clutch into a partially engaged state when a predetermined condition in which the vehicular 4-wheel drive system generates or is considered to generate a noise is satisfied in the 2-wheel drive mode.
US09440530B2 Vehicle body structure
A vehicle body structure (10) is provided with: an exhaust pipe (18) disposed between a fuel container (16) and a right framework member (12) so as to extend in the front-rear direction of the vehicle body; and a slide member (23) provided to the framework side wall (25) of the right framework member (12). The slide member (12) is provided to the portion (27) of the framework side wall (25), which is overlapped by the fuel container (16) and a chamber (42) in the width direction of the vehicle. The slide member (23) has a slide slope section (64). The slide slope section (64) is tilted inward in the width direction of the vehicle from the lower end (64b) toward the upper end (64a) so as to approach the fuel tank (16).
US09440529B2 Conformable fuel gas tank
A conformable fuel gas storage tank includes a housing that has exterior walls surrounding an interior. First and second base walls are spaced apart in a direction along a normal axis, side walls extend between the base walls and are spaced apart in a direction along a lateral axis, and end walls extend between the base walls and the side walls and are spaced apart in a direction along a longitudinal axis. Interior walls divide the interior and extend in a direction between the base walls and the end walls, and are spaced apart in a direction along the lateral axis. The interior walls establish elongate, laterally spaced, through channels extending longitudinally between the end walls. A gas storage material is located within the channels, and a gas permeable flow guide ex tends along at least one of the channels and through the gas storage material.
US09440527B1 Utility vehicle
A utility vehicle according to the invention includes a body frame supporting a cabin disposed between a pair of left and right front wheels and a pair of left and right rear wheels, a cabin front wall extending substantially throughout a vehicle width at a front end of the cabin, and an inner fender covering a lower surface of a front chamber located ahead of the cabin and above the front wheels and extending substantially throughout the vehicle width. The cabin front wall and the inner fender are connected to each other substantially throughout the vehicle width and form a front wheel space including wheel housings of the front wheels and a space between the front wheels.
US09440513B2 Absorption plate for an air conditioner
An absorption plate for a vehicle is crossed by a stream of liquid absorbent fluid flowing between two exchange surfaces arranged relatively opposite one another. The exothermal absorption of a coolant fluid in vapor phase takes place through the exchange surfaces by increasing a concentration of the coolant fluid in the absorbent fluid. The relative arrangement of the two exchange surfaces forces at least one portion of the stream of absorbent fluid to pass at least once through one of the exchange surfaces and causes mixing of the stream of the absorbed fluid.
US09440511B2 Sound deadening baffle for a ventilation valve
A baffle (10) for a venting valve for reducing the admission of sound into the interior in particular of a motor vehicle, including at least one air guiding channel (16, 18, 20, 22) having a labyrinth geometry.
US09440510B2 Mobile air cleaning unit and distribution system
A mass transit vehicle includes a frame and a cabin mounted to the frame. The cabin includes a roof and a passenger zone defining a passenger zone length. An air cleaning unit includes an air cleaner housing mounted to the roof. The air cleaning unit is operable to draw in air through an inlet, through an air cleaning device, and discharge a flow of cleaned air out of an outlet. An air conditioning unit includes an air conditioner housing separate from the air cleaner housing. The air conditioning unit is operable to draw in air through an inlet, through an air conditioning device, and discharge a flow of conditioned air out of an outlet. The outlet of the air conditioning device is in communication with a duct system to direct the flow of conditioned air to the cabin substantially evenly along the passenger zone length.
US09440508B2 Active vehicle suspension system and method for managing drive energy
A vehicle drive energy management and active suspension control system and operative methodology in which ground/pathway anomalies are sensed and the relationship thereof to the vehicle chassis is used to enable or automatically effect adjustment of chassis supporting actuators to reduce resisting effects and/or increase assisting effects of the encountered ground/pathway anomalies and thus reduce the vehicle drive energy that would otherwise be required to efficiently move the vehicle in the intended direction, yet maintain the stability of the vehicle.
US09440506B2 Modular control system
A modular control system is adapted to adjust an aftermarket system in a vehicle via the vehicle head unit. The head unit includes a user interface operable by the user to control the aftermarket system. An aftermarket control unit is in communication with the user interface of the vehicle head unit, the aftermarket control unit receiving an aftermarket control signal from the vehicle head unit as a results of an input by the user at the head unit. The aftermarket control unit is in communication with the aftermarket system, wherein the aftermarket control unit may operate the aftermarket system in response to the user input. The aftermarket system may be an air suspension system.
US09440504B2 Two-wheeled vehicle
A two-wheeled vehicle includes a frame having a front frame portion, a mid-frame portion, and a rear frame portion. The mid-frame portion is coupled to the rear frame portion and the front frame portion. The vehicle further includes a plurality of ground-engaging members for supporting the frame. The front frame portion is removably coupled to the mid-frame portion with a plurality of frame members extending between the front frame portion and the mid-frame portion.
US09440503B2 Inflation work station
An inflation work station for inflating a tire-wheel assembly including a tire mounted to a wheel is disclosed. The inflation work station includes at least one inflation probe including a female portion and a male portion. The male portion is arrangeable with respect to the female portion in one of a non-mated orientation such that the at least one inflation probe is arranged in an offline orientation and a mated orientation such that the at least one inflation probe is arranged in an online orientation. The inflation work station further includes a working device including a controller, at least one movement actuator connected to the controller and the at least one inflation probe. The at least one movement actuator imparts movement to the male portion to result in the online/offline orientation of the at least one inflation probe. The inflation work station includes at least one valve connected to the controller and the at least one inflation probe. The inflation workstation includes at least one pressurized fluid source connected to the at least one inflation probe by way of the at least one valve to permit or deny communication of a pressurized fluid of the at least one pressurized fluid source to a cavity formed by the tire-wheel assembly for inflating the tire-wheel assembly. A method is also disclosed.
US09440494B2 Airless tire construction having multiple layers
An airless tire has a wheel portion and a webbing extending from the wheel portion towards an axis of rotation of the airless tire. The diameter of an annular outer surface of the wheel portion varies along an axial direction of the airless tire.
US09440491B1 Tire lift caddy
This tire lift caddy has a rectangular frame supported on casters, and a pair of rollers mounted therein across the frame. The rollers are guided along a respective pair of inclined slots in the side of the frame. A threaded rod extends along a length of the frame. A pair of push bar assemblies are mounted to the threaded rod and to the axles of said rollers for moving the rollers in unison along the slots upon a rotation of the threaded rod. The threaded rod has a left-hand thread thereon and a cylindrical handle on a working end thereof. The cylindrical handle can be worked with the palm of the hand, or finely adjusted with the fingers to raise the rollers to a desired level. The rollers have a central groove in surfaces thereof for nesting the threaded rod therein when the rollers are in their lowermost positions.
US09440488B1 Hubless wheel system for motor vehicles
The hubless wheel system includes an inner ring assembly having a main stationary ring and a plurality of inner ring mounting brackets positioned within the main stationary ring, a first bearing and a second bearing mounted onto the main stationary ring, a side plate positioned in communicating relation with the second bearing, a middle ring assembly mounted onto the bearings of the inner ring assembly, and an outer ring mounted on the middle ring assembly. The middle ring assembly has a middle ring and a brake disc positioned in communicating relation with the middle ring. The outer ring has an inner portion and a plurality of outer ring mounting brackets positioned on the inner portion of the outer ring, and a bracket assembly positioned within the main stationary ring. The hubless wheel system can include a drive assembly, a step-lock assembly, a side wheel assembly, and a suspension assembly.
US09440487B2 Cardboard made wheel
Some embodiments are directed to a generally planar wheel, including a multi-layer cardboard body having at least one layer of a high-density cardboard sheet sandwiched between at least two layers of low-density cardboard sheet.
US09440485B2 Paint caddy
A paint caddy includes a base having at least two walls and a pole coupled to and extending upwardly from the base. The base has at least one base support extending between the walls for capturing and supporting a paint tray therebetween. The pole has at least a substantially vertical portion and a substantially horizontal portion, with the substantially horizontal portion serving as a handle for carrying a paint tray. A hook extends from the pole and is positioned below and spaced from the handle.
US09440480B2 Double-layered sheet systems
A magnetic sheet system providing flexible magnetic sheets that are digitally printable on both sides and that serve as magnetic postcard stocks for production of customized magnetic postcards.
US09440478B2 Paper binding device, paper processing apparatus, image forming apparatus, and image forming system
A paper binding device comprises: a pair of binding members that has a pair of teeth portions, and presses to bind a bundle of paper sheets; a moving unit that causes one of the pair of binding members to move along with the other of the pair of binding members between a binding position at which the bundle of paper sheets is bound and a retracted position; a separating unit that moves coordinating with movement of the one of the pair of binding members, and when the one of the pair of binding members moves from the binding position to the retracted position, that contacts with the bundle of the paper sheets and causes the bundle of paper sheets to separate from the one of the pair of binding members; and a restricting member that stops the separating unit at a restricting position between the binding position and the retracted position, when the one of the pair of the binding members moves from the binding position to the retracted position.
US09440470B2 Printing apparatus and printing method
A printing apparatus measures spectral intensity of a printed medium before an image is printed thereon, and calculates Mahalanobis distances with respect to plural types of reference printing media stored in advance. Then, the type of the printed medium is determined from the reference printing media based on the Mahalanobis distances and the image is printed thereon.
US09440469B2 Paper discharge mechanism, printing device, and terminal equipment
The paper discharge mechanism comprises: a first side passage plate and a second side passage plate between which an S-shaped paper conveying passage is formed, wherein the second side passage plate comprises a paper jam detection plate and a paper pullout detection plate both pivotally connected on a frame; a first elastic element biasing the paper jam detection plate and a second elastic element biasing the paper pullout detection plate; and a first sensor and a second sensor. A surface of the paper jam detection plate facing paper is concave and is held against the paper and rotates in the direction away from the first side passage plate during paper jam; a surface of the paper pullout detection plate facing the paper is convex and is held against the paper and rotates in the direction away from the first side passage plate during paper pullout.
US09440466B2 Transport mechanism and method for transporting a print medium in a printing system
A transport mechanism is provided for transporting sheets of a print medium in a printing system. The transport mechanism include a first conveyor device having a first conveyor body which is configured to support a plurality of sheets of print medium, the first conveyor body being movable to convey the sheets along the transport path in the printing system; and a transfer system including a second conveyor device having a movable second conveyor body for supporting the sheets of print medium and conveying the sheets further along the transport path, the transfer system being configured to transfer the sheets of print medium from the first conveyor body to the second conveyor body in a transfer region. The second conveyor body is arranged adjacent or proximate to the first conveyor body in the transfer region, and the transfer system includes spacer means which is configured to maintain a predefined spacing between the first conveyor body and the second conveyor body in the transfer region. An associated method of transporting sheets of a print medium in a printing system is also disclosed.
US09440465B2 Printing apparatus, method of controlling the same, and storage medium
A printing apparatus includes: a printing unit having a plurality of printing elements arranged in a conveyance direction of the printing sheet and configured to print the printing sheet; a conveyance control unit configured to control conveyance of printing sheets so that a trailing edge of a preceding sheet as a printing sheet precedingly fed from the stacking unit and a leading edge of a succeeding sheet as a printing sheet fed after the preceding sheet overlap each other; a determination unit configured to determine, under a predetermined condition, whether to convey the succeeding sheet to a position facing the printing unit while keeping an overlap state between the preceding sheet and the succeeding sheet; and a printing control unit configured to control, based on a determination result of the determination unit, printing elements of the printing unit to be used.
US09440461B2 Printing apparatus
An inkjet printing apparatus is selectively composed of a plurality of transportation units, i.e., an inlet unit, a first intermediate unit, a second intermediate unit, and an outlet unit, having a transport path with slopes in side view of a transportation direction from a paper feeder to a take-up roller. When the transportation units are connected, a connecting part of the transportation unit is an inclination change point VP of the transport path. This achieves maintained tension to the print medium. As above, the inkjet printing apparatus may be selectively composed of a plurality of transportation units. Accordingly, the inkjet printing apparatus is constructible by combination of the units for various type productions, leading to a suppressed stock.
US09440459B1 System and method for treating surface of media with a digitally addressable dryer array to reduce moisture gradient and media cockle
A printer comprises at least one printhead having a plurality of inkjets, a dryer having an array of radiators including a plurality of rows of radiators and a plurality of columns of radiators, a media transport configured to move media past the at least one printhead and the dryer, and a controller operatively connected to the at least one printhead, the dryer, and the media transport. The controller is configured to activate selectively the radiators in the array of radiators to heat the portions of the surface of the media on which ink has been ejected. A method for operating the printer is also disclosed.
US09440458B2 Liquid application apparatus and image forming system
A liquid application apparatus includes a first container, an applicator, a squeezer, a second container, a retreat passage, a filter, an on-off valve, and a sensor. The first container stores a pretreatment liquid before image forming. The retreat passage communicates the first container with the second container. The filter is disposed on the retreat passage to remove foreign substances from the liquid. The on-off valve is disposed between the second container and the filter on the retreat passage. The sensor is disposed at the first container to detect a liquid level of the first container in at least two positions different in height and obtain a flow rate of the liquid in the retreat passage based on a period during which the liquid level moves between the positions when the on-off valve is opened and the liquid stored in the first container is transferred to the second container.
US09440456B2 Dual purpose printing apparatus
According to one embodiment, a dual purpose printer has a housing, a printing medium supporting section, a first printing section, and a second printing section. The housing has a discharge port and an entrance port. The printing medium supporting section is arranged inside the housing, and rotatably supports a rolled printing medium. The first printing section is configured to print on a top surface of a first continuous sheet printing medium drawn from the rolled printing medium supported on the printing medium supporting section, and to print on a second printing medium carried in through the entrance port. The second printing section is arranged inside the housing, and is configured to print on the bottom surface of the first continuous sheet printing medium.
US09440454B2 Printer
The disclosure discloses a printer including a storage part, a feeding roller, a printing head, a core driving device, and a controller. The controller is configured to execute a feeding process, a printing process, a taking-up process, and a torque correction process. In the feeding process, the feeding roller is driven to feed the print-receiving tape fed out from the print-receiving tape roll. In the printing process the printing head is controlled to form a desired print, thereby a printed tape is formed. In the taking-up process, the core driving device is driven to sequentially take up the printed tape around an outer circumferential portion of a second core. In the torque correction process, a drive torque of the core driving device is corrected from a first drive torque to a second drive torque corresponding to a tape width of the print-receiving tape.
US09440451B2 2-D straight-scan on imaging surface with a raster polygon
A 2-D scanning system uses a fast-rotating raster-polygon as a single scanning component to produce straight scan lines over a 2-D image surface. An approach angle of incident light beams to the raster-polygon is selected to minimize pin-cushion distortion of scan lines introduced by polygon scanning on the image surface, and a tilt angle of the rotational axis of the raster-polygon is selected to position said polygon-scanning distortion symmetrically on the image surface. In addition, scan optics are configured to generate a predetermined amount of barrel distortion of scan lines on the image surface to compensate for pin-cushion distortion introduced by polygon scanning.
US09440448B2 Sheet processing apparatus, and method and computer-readable medium therefor
A sheet processing apparatus including a controller configured to move a carriage from an initial position to such a position that an optical sensor traverses one of two side edges of a sheet in a scanning direction, in a direction along the scanning direction, in response to the sheet reaching a position opposed to the optical sensor, adjust a light emitting quantity of the optical sensor while the carriage is being moved, within a period from when the carriage begins to move from the initial position to when the optical sensor traverses the one side edge, calculate a position of the one side edge traversed by the optical sensor after the adjustment, based on detection values, corresponding to the light receiving quantity, output from the optical sensor after the adjustment, and identify edge positions of the two side edges based on the calculated position of the one side edge.
US09440444B2 Liquid management system
A liquid management system for supplying or receiving liquid at a controlled pressure, comprising: a closed reservoir having an inlet for receiving liquid from a first remote location and an outlet for supplying liquid to a second remote location; and a pumped outlet disposed in the reservoir and arranged to remove liquid and gas contained within the reservoir, the pumped outlet being disposed such that the level of liquid in the reservoir can be maintained at a constant height.
US09440443B2 Liquid ejecting head and liquid ejecting apparatus
A liquid ejecting head is provided with a suction port capable of avoiding the return of mists, which have already been sucked through a suction port, back to the suction port. In view of this, the inner diameter of a suction tube for allowing liquid mists taken in through the suction port to pass is designed such that a meniscus is formed before a liquid droplet adhering to the inside of the suction tube grows enough to move toward the suction port.
US09440442B2 Printhead assembly datuming
In one example, a datuming system to position a printhead assembly relative to a component external to the printhead assembly includes first primary datum points and second primary datum points. The first primary datum points establish a first datum plane to position the printhead assembly relative to a first component external to the printhead assembly. The second primary datum points establish a second datum plane to position the printhead assembly relative to a second component external to the printhead assembly.
US09440439B2 Ink-jet head and ink-jet recording apparatus
The inkjet head for discharging a water-based ink for inkjet recording is disclosed, the inkjet head including two or more types of metal members used at portions to be brought in contact with the water-based ink, wherein at least two of the two or more types of the metal members are electrically connected, and the two or more types of the electrically connected metal members have spontaneous potentials each of which is measured with a reference electrode Ag/AgCl in the water-based ink and which provide an absolute value of a maximum difference therebetween, the absolute value being not more than 60 mV. An ink jet head is provided, in which any corrosion of a metal member is suppressed.
US09440437B2 Liquid discharge apparatus and method for driving liquid discharge head
A liquid discharge apparatus comprises: a liquid discharge head that discharge a liquid by varying a volume of a pressure chamber with an actuator; a control unit that generates a drive signal that varies the volume of the pressure chamber; and an actuator driving unit that drives the actuator with the drive signal, wherein the drive signal includes a plurality of discharge pulses and a non-discharge pulse, the non-discharge pulse is applied at a time point at which a vibration velocity of a composite residual vibration that is of a liquid near a nozzle and that is generated by the discharge pulses peaks in a direction toward an inside or outside of the nozzle, the time point being synchronized with an intermediate time point between a fall time point and a rise time point of the non-discharge pulse.
US09440435B2 Liquid discharge control apparatus and liquid discharge control method
A liquid discharge control apparatus includes a discharge control unit that controls the discharge of the liquid through the nozzle. In the case that the discharge control unit allocates, to a first nozzle, the pixel of a first ratio in a pixel column that represents one raster line, and allocates, to a second nozzle, the pixel of a second ratio in the pixel column, and in the case that one nozzle of the first nozzle and the second nozzle is an abnormal nozzle, and the ratio of the pixel in the pixel column allocated to the one nozzle is more than or equal to a predetermined ratio with respect to a total of the first ratio and the second ratio, the discharge control unit increases the ratio of the pixel in the pixel column allocated to the other nozzle of the first nozzle and the second nozzle.
US09440434B2 System and method for using ink drop modulation to compensate for media surface height variations in an inkjet printer
A printer attenuates banding visual defects arising from a lack of flatness in media as ink is ejected onto the media. The printer includes a detector that generates a signal corresponding to the slope in the media and a controller that modulates a volume of the ink drops ejected by one or more printheads in the vicinity of the slope in the media.
US09440433B2 Liquid discharging apparatus, head unit, and control method of liquid discharging apparatus
Provided is a liquid discharging apparatus which includes a modulation circuit which generates a modulation signal which is obtained by pulse-modulating a source signal, a transistor which generates an amplified modulation signal by amplifying the modulation signal, a low pass filter which generates a drive signal by smoothening the amplified modulation signal, a piezoelectric element which is displaced by receiving the drive signal, and a circuit substrate on which the transistor is mounted. The transistor includes a first electrode, a second electrode, a third electrode, and a clip which has conductivity, is electrically connected to the first electrode. Furthermore, the circuit substrate has a first land corresponding to the first electrode, a second land corresponding to the second electrode, and a third land corresponding to the third electrode. In addition, a part of the clip is connected to the third land.
US09440432B2 Image recording device
In an image recording device, in a case where a J-th nozzle (H2 [3]) of a certain image recording head (H2) among plural image recording heads (H1, H2) is in a discharge defect state, a dot size of an image recording droplet discharged from a J-th nozzle (H1 [3]) of an image recording head (H1) other than the image recording head (H2) is changed to a size within dot sizes used in normal image recording in a high-speed image recording mode, which is larger than a dot size of an image recording droplet to be discharged from the discharging nozzle (H2 [3]). In a low-speed image recording mode, the dot size of the image recording droplet discharged from the discharging nozzle (H1 [3]) is changed to a size which is larger than the largest dot size among dot sizes used in the normal image recording.
US09440426B2 Ink proofing system
An ink proofing system may include a hand holdable support member, an anilox roll coupled to the support member and an impression roll coupled to the support member. A photopolymer printing plate with an etched outer surface can be coupled to the outer circumferential surface of the impression roll. An adjustment device coupled to the support member can be provided to set a fixed nip between the printing plate and the ink-receiving substrate.
US09440424B2 Methods to form and to dismantle hermetically sealed chambers
Embodiments generally relate to methods for forming and dismantling a hermetically sealed chamber. In one embodiment, the method comprises using room temperature laser bonding to create a hermetic seal between a first element and a second element to form a chamber. A bond interface of the hermetic seal is configured to allow the hermetic seal to be opened under controlled conditions using a release technique. In one embodiment, the chamber is formed within a microfluidic chip and the chamber is configured to hold a fluid. In one embodiment a chip comprises a first hermetic seal bonding first and second elements to create a first chamber and a second hermetic seal bonding third and fourth elements to create a second chamber encompassing the first chamber. The first hermetic seal may be broken open independently of the second hermetic seal by the application of a mechanical or thermal technique.
US09440423B2 Vacuum lamination machine suitable for all generations and operation method thereof
A vacuum lamination machine suitable for all generations is disclosed. The vacuum lamination machine includes a stage on which a transfer device, a positioning device, an adhesive application device, a turn-over device, and at least one vacuum lamination device are arranged. The stage has a size that is sufficiently large for all sizes of substrate. The transfer device includes a fork that is adjustable for spacing distance to suit for substrate sizes. The turn-over device includes sufficiently densely arranged vacuum suction pins to suit for substrate sizes. The positioning device includes a size identification system that identifies a rough location of a substrate on the stage and a mark position identification system that carries out precise alignment of the substrate.
US09440422B2 Peel-resistant mechanism for use in bonding components
A peel-resistant mechanism includes a body and a plurality of arms extending from the body such that a recess is defined between each pair of adjacent arms. At least one of the arms is positionable to facilitate restricting an edge disbond from spreading across the body of the patch.
US09440419B2 Photochromic polyurethane laminate
Photochromic polyurethane laminates and methods for the formation of same wherein a photochromic polyurethane layer of the laminate is interposed between two primer coated transparent resin sheets.
US09440417B2 Method of making a metal-strip laminate
A metal laminate is made by first laying at least one first metal strip of at least one first metal having a thickness of 40 μm to 750 μm on at least one second metal strip of a second metal different from the first metal to form a multilayer stack having a total thickness between 2 mm and 15 mm. Then the first and second strips of the multilayer stack are bonded together by rolling. Finally a finished laminate is formed by reducing a thickness of the bonded-together first and second strips by rolling in at least one pass such that the one first metal strip has a thickness of 0.5 to 10 μm.
US09440416B2 Weight-bearing adhesives with adjustable angles
The invention provides unique releasable adhesive devices that are high-load bearing and highly stable while allowing adjustment of the weight-bearing angle in a wide range, thereby greatly expanding the scope of applications for technology. Adhesive systems and devices of the invention can be designed to fit applications ranging from household weight-bearing shelves and holders, components for transportation, athletic equipment, labels and advertising posts, automobile interior trims, permanent or reversible fasteners, as well as instruments and devices for industrial, commercial, medical or military applications.
US09440411B2 Living roof and wall systems using cultivated mineral wool mats to support BLAVEs, methods of cultivation and innoculants therefor
Soil-free living roof and wall systems comprising a living layer of Bryophytes, Lichen, And Vascular Epiphytes (BLAVE) on the surface of a thin, light-weight, flexible, fire-resistant mat of mineral wool having a density in the range of about 6-12 lbs/cu ft and thickness in the range of about ⅜″ to about ¾″. Mats are provided in modular units on the order of 2′×4′; no irrigation or growth medium is used. The mats are adhered to a roof or wall with adhesive or mastic, or may be secured with fasteners. In the preferred embodiment, modular units include flexible mineral wool mats over a base sheet of non-woven plastic fibers, on the order of from 2-4 mm thick, and a wide-mesh plastic netting over the BLAVE layer, sewn through to the base layer. Methods of mat module manufacture, innoculant mix production, installation and cultivation/propagation of BLAVE are disclosed.
US09440410B2 Cardboard container
The present invention relates to a container, particularly a cup, with a base and a first sidewall, wherein the first sidewall comprises at least a first, at least partially circumferential shaping directed inwardly and/or outwardly. The container may also include a second sidewall attached to the shaping of the first sidewall at a connection point thereby providing an air gap between the first sidewall and second sidewall. The shaping of the first sidewall may include a tip to which the second sidewall is sealed or glued.
US09440406B2 Pneumatic tire and method of forming circumferential belt layer of the same
The present invention relates to a method of forming at least one circumferential belt layer of a pneumatic tire comprising: winding the strip for a half length of an outer circumferential length of the crown portion of the carcass along the tire equatorial plane from a widthwise inner side of the belt end region; winding the strip for the remaining half length while shifting the strip for the width of the strip from a widthwise inner to outer side; winding the strip for the outer circumferential length of the crown portion of the carcass along the tire equatorial plane; winding the strip for the half length of the outer circumferential length of the crown portion of the carcass while shifting the strip for the width of the strip from the widthwise outer to inner side; and winding the strip for the remaining half length along the tire equatorial plane.
US09440400B2 Plural-component, composite-material highway dowel bar fabrication methodology
A method for making a plural-component, composite-material, highway dowel-bar including (1) preparing an elongate core train possessing endo-abutting, longitudinally alternating, (a) elongate, high-shear-strength, cylindrical cores having a common cross section, and (b) elongate, but shorter, cylindrical, fiber-reinforced plastic-resin end-plug blanks having opposite ends, and each having a cross section matching the cross section of the cores, (2) using the core train as a longitudinally moving mandrel, pultrusion-forming a fiber-reinforced plastic-resin sleeve continuously and bondedly around the core train so as to produce a pultrusion-result, intermediate, dowel-bar product, and (3) following pultrusion-forming, cross-cutting the intermediate, dowel-bar product at each longitudinal location therein which is intermediate the opposite ends of the end-plug blanks, thereby to form completed dowel bars.
US09440394B2 Methods of mechanically deforming materials
Methods of mechanically deforming a material are disclosed. The methods of mechanically deforming a material involve using forming members that are moving at different surface speeds relative to each other to form deformed web materials.
US09440392B2 Blow mold unit, blow molding machine and blow mold unit fixing method
A blow mold unit in which, when clamping first and second blow cavity split molds which are fixed to first and second fixing plates and bottom molds which are fixed to a bottom mold fixing plate, pressure receiving members fixed to the first and second fixing plates are brought into engagement with the bottom plate fixing plate. Guide plates are fixed to the bottom mold fixing plate, and guided members capable of being brought into abutment with the guide plates are supported by first and second pressure receiving plates. The bottom mold fixing plate includes a first connecting portion to be connected to a bottom mold opening/closing unit and a second connecting portion to be connected to a moving and biasing member.
US09440391B2 Pellet press with a cutting-to-length device for biogenic fibrous pellets
A cutting-to-length device for a pellet press has at least one cutting-to-length means for biogenic fibrous pellets, especially wood pellets, and a fastening area, in which the cutting-to-length device can be fastened to a stationary housing part of the pellet press. The cutting-to-length means can be arranged in the radially outer area of a rotation annular die of the pellet press and at a distance from the annular die which has radial through-holes. The cutting-to-length mechanism has a concave arched contour and is attached on the radially outer area of the annular die by means of the fastening area so that the cutting-to-length mechanism extends largely helically with its curvilinear contour over the area of the radial through-holes of the annular die. Furthermore, the invention refers to a pellet press with at least one such cutting-to-length device.
US09440387B2 Nozzle of injection machine and heating apparatus of the nozzle
A heating apparatus for a nozzle of an injection machine includes a helical-spring shaped heating portion, a first sleeve, and a second sleeve. The first sleeve includes a first blocking portion and forms internal threads. The second sleeve includes a second blocking portion and forms external threads. The heating portion is received in the second sleeve. The internal threads are screwed into the external threads. The first blocking portion and the second blocking portion sandwich the heating portion.
US09440382B2 Method of manufacture of polytetrafluoroethylene stretched film, and polytetrafluoroethylene stretched film
A method of manufacturing a PTFE stretched film that has higher tensile strength at its breaking point. In the method, a resin composition is obtained by mixing an emulsion of PTFE (A) with a number average molecular weight of 5×106 or more and an emulsion of PTFE (B) with a number average molecular weight of 1×106 to 4×106 so that the solid content ratio (A/B) of the PTFE (A) and the PTFE (B) is 99/1 to 10/90. The mixed emulsion is subjected to compression molding in a melted state under a reduced-pressure atmosphere to obtain a film.
US09440380B2 Component and associated production method
A method for producing an intake module may include providing a housing and at least one intercooler arranged therein; forming at least two housing parts via injection molding from plastic; inserting at least one intercooler into at least one of the housing parts; wherein the housing parts, with at least one intercooler inserted therein, are welded together to form the housing; and wherein the intercooler has contact points to at least two of the housing parts.
US09440378B2 Planar electronic device and method for manufacturing
A method of manufacturing a planar board substrate for receiving a magnetic core. The method includes providing a cover layer having a layer side and providing a base layer having first and second sides. The base layer includes a material hole that extends completely through the base layer between the first and second sides. The method also includes coupling the cover and base layers to each other along the first side and the layer side. The cover layer extends over at least a portion of the material hole. The method also includes providing a dielectric member within the material hole, wherein a core-holding channel exists between the dielectric member and the base layer. The core-holding channel extends circumferentially around the dielectric member and is configured to have a magnetic core therein.
US09440375B2 Blank for mold production and method for manufacturing mold
A hard mask film 2 provided on substrate 1 is formed by tin-containing chromium-containing material. In the chromium-containing material including tin, which forms the hard mask film 2, the etching resistance to fluorine-containing dry etching is equal to or higher than the etching resistance of the tin-free chromium-containing material, and it shows a significantly high etching rate as compared with a chromium-containing material free of tin under conditions for chlorine-containing dry etching. As a result, the time for chlorine-containing dry etching is shortened, and damage to a resist pattern is reduced. Thus, high-precision pattern transfer can be performed. The present invention provides a novel technique for increasing etching process-ability by increasing a dry-etching rate of a hard mask film made of a chromium-containing material while assuring a hard mask function of the hard mask film.
US09440374B2 Device and method for producing polymer agglomerates
The invention relates to a device (1) for producing polymer agglomerates, comprising a compounder (2) having a housing (21) and a twin screw (22) arranged therein as well as a plurality of material inlets (3, 4) for admission of a polymer and additives, tempering units for heating the mix comprising polymer and additives, at least one degassing unit (5) and an outlet (23) and an agglomerating vessel (11) having an agglomerating tool (8) and a cooling tool (10). The agglomerating vessel (11) is connected via a connection channel (6) to the outlet (23) of the compounder (2), wherein the twin screw (22) of the compounder (2) is designed as a co-rotating twin Screw (22) and the agglomerating tool (8) of the agglomerating vessel (11) is arranged in the fall direction of the mix below the connection channel (6) and comprises mutually engaging rotors (81) and stators (82) for producing agglomerates of defined particle size. The invention further relates to a method for producing polymer agglomerates.
US09440372B2 Process for treating wood
The proposed invention relates to a method for fluid treatment of wood comprising the steps of placing the wood in an airtight tank, evacuating the airtight tank to establish a vacuum environment for the wood, applying a fluid to the wood. Additionally, the method may further comprise the subsequent step of pressurizing the airtight tank to establish a pressurized environment for the wood. The method may further comprise the subsequent step of subjecting the wood to a subsequent heating, and/or the prior step of subjecting the wood to a prior heating by electromagnetic radiation through one or more electrodes.
US09440369B2 Device to remove binding materials from packaged bulk goods
The invention relates to a device 1 to remove binding materials 2 from packaged bulk goods 3, particularly binding wire or binding cord from compressed cuboid bales as packaged bulk goods. In order to have an automated process during removal of binding materials, a transport unit 4 is provided to transport the packaged bulk goods 3 into a gripping and cutting station 6 at which the package of bulk goods 3 is affixed on the one side by a clamping device 8 and on the other side of the package of bulk goods by a cutting device 7, and binding materials 2 are gripped by the clamping device 8 and cut by the cutting device 7.
US09440365B2 Reciprocating linear razor
The present invention pertains to a razor, which includes: a gripping section combined with a housing; a head section coupled at one side of the housing; a razor blade cartridge mounted at a front surface of an upper end of the head section; and an eccentric cam module, which moves the razor blade cartridge to reciprocate in a cutting direction.
US09440363B2 Robot and manufacturing method of the same
A robot according to an aspect of an embodiment includes a robot arm, an attaching portion, an end effector, an end-effector-side cable, and a robot-side cable. The attaching portion is provided on a leading end of the robot arm. The end effector is attached to the attaching portion. The end-effector-side cable extends from the end effector. The robot-side cable is arranged along the robot arm and is connected to the end-effector-side cable by terminal connection at a position closer to the end effector than the attaching portion.
US09440362B2 Robotic arm with spherical linkage
A robotic arm includes first and second bent links and a tool link pivotally connected in order, first to third wheels, and first to fourth imaginary axes intersecting at a center of spherical rotation. The first bent link and wheel are driven to rotate about the first and third imaginary axes respectively. A first flexible rope is wound around the first and second wheels and fixed to the second bent link for driving the second wheel and bent link to rotate about the second imaginary axis when the first wheel rotates. A second flexible rope is wound around the second and third wheels and fixed to the first bent link for driving the third wheel and the tool link to rotate about the fourth imaginary axis when the second wheel rotates. The robotic arm is relatively smaller, obstructs the operator less and produces a wider sphere of action.
US09440361B1 Activation element and method
An apparatus has a first member and a second member that is movable relative to the first member. The apparatus also has an activation element connected to the first member. The activation element also is wrapped about at least a portion of the second member.
US09440360B2 Change-over coupling
A change-over coupling (1) for robot-guided vehicles (3) has a plurality of media couplings (11, 12) and has coupling parts (4, 5) having basic supports (6, 7), media coupling supports (13, 14) and a coupling mechanism (8), and also peripherally arranged interfaces (16) having a fitting element for the media couplings (11, 12). The interfaces (16) have a plurality of fitting elements (19, 19′, 20, 20′), which act in a plurality of different directions or axes and which are arranged preferably at a periphery, in particular on a circumference of a disc-like or annular basic support (6, 7).
US09440357B2 System for stabilization control of mobile robotics
A system comprises a platform being configured for locomotion in a plurality of directions over a surface. A robotic unit is configured for dexterous manipulation comprising at least lifting of objects. The robotic unit is joined to the platform. At least one extender unit is joined to the platform and is configured for controlled extension beyond the platform to contact the surface to stabilize the system at least during the manipulation by the robotic unit. At least one controlling unit is configured to be operable for at least determining a center of gravity and a zero moment point for the system and for at least controlling an extension of the extender unit.
US09440356B2 Customizable robotic system
A telepresence robot uses three separately controlled omni-wheels and a computer processing arrangement to reposition the robot based on received positional signals. The telepresence robot captures and transmits visual information of a limited field of view and visual information of a broad field of view. The visual information is received and displayed on a remote input device and portions of the displayed information are selected to send an appropriate signal to reposition the robot based on the selected portion. A method of remotely controlling a telepresence robot is also disclosed.
US09440354B2 Localization by learning of wave-signal distributions
A robot having a signal sensor configured to measure a signal, a motion sensor configured to measure a relative change in pose, a local correlation component configured to correlate the signal with the position and/or orientation of the robot in a local region including the robot's current position, and a localization component configured to apply a filter to estimate the position and optionally the orientation of the robot based at least on a location reported by the motion sensor, a signal detected by the signal sensor, and the signal predicted by the local correlation component. The local correlation component and/or the localization component may take into account rotational variability of the signal sensor and other parameters related to time and pose dependent variability in how the signal and motion sensor perform. Each estimated pose may be used to formulate new or updated navigational or operational instructions for the robot.
US09440349B2 Automatic tire loader/unloader for stacking/unstacking tires in a trailer
An automatic tire loader/unloader for stacking/unstacking tires in a trailer is disclosed. In one embodiment, a mobile base structure provides a support framework for a drive subassembly, conveyance subassembly, an industrial robot, a distance measurement subassembly, and a control subassembly. Under the operation of the control subassembly, tires advance through a powered transportation path to an industrial robot which places the tires within the trailer in a vertical stacking pattern or a rick-stacking pattern, for example. The control subassembly coordinates the selective articulated movement of the industrial robot and the activation of the drive subassembly based upon the distance measurement subassembly detecting objects, including tires, within a detection space, dimensions of the trailer provided to the control subassembly, and dimensions of the tires provided to the control subassembly.
US09440344B2 Dust collecting device and impact tool
A dust collection device, that collects dust particles generated by an impact tool, has a feature that enables the attachment of the device to the impact tool, which is not provided with an attachment section for the device. The dust collection device has a tool body and an auxiliary handle, attached removably to the tool body, and is attached to an electric hammer that, in the lengthwise direction, linearly operates a tool bit mounted to the tip region of the tool body, and collects dust generated by the electric hammer. The dust collection device has: a dust collection unit that has a dust intake port at the tip; a dust collection hose, connected to the dust collection unit, for transferring dust to the downstream side; and a hose-holding unit that holds the dust collection hose. The hose-holding unit can be attached to and removed from the auxiliary handle.
US09440333B2 Methods of forming polycrystalline elements from brown polycrystalline tables
Methods of forming a polycrystalline table may involve disposing a plurality of particles comprising a superabrasive material, a substrate comprising a hard material, and a catalyst material in a mold. The plurality of particles may be partially sintered in the presence of the catalyst material to form a brown polycrystalline table having a first permeability attached to an end of the substrate. The substrate may be removed from the brown polycrystalline table and catalyst material may be removed from the brown polycrystalline table. The brown polycrystalline table may then be fully sintered to form a polycrystalline table having a reduced, second permeability. Intermediate structures formed during a process of attaching a polycrystalline table to a substrate may include a substantially fully leached brown polycrystalline table. The substantially fully leached brown polycrystalline table may include a plurality of interbonded grains of a superabrasive material.
US09440330B2 Shot blast cleaning wheel blade and blade and wheel combination
An improved shot blasting blade is disclosed with an attachment portion designed to slide into a radial slot in a shot blasting wheel. The blade has rails that contactingly ride on a top surface of the wheel just outside the slot, and two sets of opposed runners that extend into the slot and contact the top inner surface of the slot.
US09440321B2 System for positioning a workpiece on a machine worktable
A system for positioning a workpiece on the worktable of a machine including at least one stop device mounted on such machine, including a first component provided with a fluid passageway having an inlet connected to a fluid pressure line including a pressure sensor, and an outlet disposed in an abutment surface thereof, and a second component displaceable relative to such abutment surface, into and out of obstructive relation with such outlet, affecting the pressure in such supply line and correspondingly effecting a hold down of a workpiece positioned on such worktable.
US09440320B2 Support and gripping device of a mechanical part, suitable for a machine tool
A machine tool (2) comprising a mobile table (11) and a support and gripping device (200) fitted to one said machine tool (2) and which comprises:—pincer means (210) for blocking the part;—a support (250) which contains and supports the pincer means (210) and is blocked to the mobile table (11). The pincer means (210) comprise a part blocking pincer (212) and an intermediate pincer (211), respectively one inside the other, both elastic. The part blocking pincer (212) has a structure for gripping the part following interaction between the intermediate pincer (211) and the support. (250); in addition the pincer means (210) are suitable for being placed in rotation around the pincer axis (P-P).
US09440316B2 Circular galley drain strainer
A drain strainer assembly includes a housing having a circular cross-section, with an inlet port, an outlet port, and a plurality of first engagement tabs. The drain strainer assembly also includes a strainer member assembly having a circular cross-section. The strainer member assembly includes a strainer member with a solid front surface having a handle and a plurality of second engagement tabs interlocked with the first engagement tabs on the housing. The strainer member also includes cylindrical strainer sidewalls defining a circular opening at the back of the strainer member, and has an upper conduit aligned with the inlet port of the housing. The strainer member assembly also includes a circular strainer disk coupled to the strainer member with a fastener and covering the circular opening at the back of the strainer member.
US09440315B2 Aluminum alloy heat exchanger and method of producing refrigerant tube used for the heat exchanger
An aluminum alloy heat exchanger is produced by applying a coating material that is prepared by adding a binder to a mixture of an Si powder and a Zn-containing compound flux powder to a surface of an aluminum alloy refrigerant tube, assembling a bare fin that is formed of an Al—Mn—Zn alloy with the refrigerant tube, and brazing the refrigerant tube and the bare fin by heating in an atmosphere-controlled furnace, the refrigerant tube being an extruded product of an aluminum alloy that comprises 0.5 to 1.7% (mass %, hereinafter the same) of Mn, less than 0.10% of Cu, and less than 0.10% of Si, with the balance being Al and unavoidable impurities, a mixing ratio of the Si powder to the Zn-containing compound flux powder being 10:90 to 40:60, the binder being added in an amount of 5 to 40% based on the total amount of the coating material, the coating material being applied to an outer surface of the refrigerant tube so that the total amount of the Si powder and the Zn-containing compound flux powder is 5 to 30 g/m2, the surface of the refrigerant tube subjected to brazing having a potential lower than that of an area of the refrigerant tube that is deeper than a diffusion depth of Si and Zn by 20 to 200 mV, and a potential of the fin being lower than that of a deep area of the refrigerant tube.
US09440314B2 Laser welding assembly and method
A hybrid laser arc welding assembly including a gas metal arc welding torch and a laser arc welding laser head. The torch and laser head are disposed adjacent one another and aimed at targets of a pair of work pieces spaced from one another such that the melted material produced by the torch overlaps with the melted material produced by the laser head, and therefore, the torch and laser head combine to create a hybrid laser arc weld to join the work pieces. The laser head is adjustable dynamically relative to the work-pieces to optimize the hybrid laser arc weld.
US09440313B2 Hard drive data destroying device
Three systems for the destruction of the data storage portion of electronic media storage devices such as hard disk drives, solid state drives and hybrid hard drives. One system utilizes a mill cutter with which the hard drive has relative motion in the direction of the axis of the mill cutter to destroy the data storage portion. A second system utilizes a laser to physically destroy the data storage portion. The third system utilizes a chemical solvent to chemically destroy the data storage portion.
US09440311B2 Methods and apparatus for separating a substrate
This invention relates to slicing a thin semiconductor substrate from side wall into two substrates of half thickness. The substrate slicing process involves a laser irradiation step. The substrate slicing process can also involve a mechanical cleaving process after the laser irradiation step. The apparatus for substrate slicing comprises two opposite-facing substrate chucks, with a gap in between for the substrate to pass through. One portion of the two substrate chucks are in parallel to each other to center the substrate sidewall. The gap can increase between the second portion of the two substrate chucks after the location for substrate separation, to spread out the resulting two substrates after the slicing and to facilitate the continuous substrate separation process. The present invention is further directed to methods and apparatus of separating a continuous thin layer of materials from side wall of a rotating ingot. It can be accomplished by a laser irradiation on the ingot side wall from a tangential direction for materials ablation. In an alternative method, a high-intensity short-pulse laser irradiates on the ingot side wall from a radial direction and converges under the ingot sidewall surface to form a plane of modified region inside the substrate, and a thin layer of materials is separated from the ingot side wall along the plane of modified region in a subsequent mechanical cleaving step. A film can be deposited/bonded to the ingot side wall prior to the separation of the thin film layers. The resulting thin layer of materials can be pulled away from the ingot by a substrate chuck.
US09440308B2 Resistance welding electrode
A welding electrode according to the disclosure includes a body. A head is secured to the body and includes an aperture through which a pin extends. A polymer insulating sleeve is arranged between the pin and the head, for example. The sleeve material extends radially from an inner diameter to an outer diameter. The outer diameter engages the head, and the inner diameter is in close proximity to and engagement with the pin, which slides axially relative to the sleeve. The head and sleeve include first and second interlocking features that cooperate with one another to retain the sleeve in the aperture. The sleeve is arranged inboard from an outer face of the head, which is used to support a work piece.
US09440306B2 Spot welding system including spot welding gun
A spot welding system (1) includes a welding pressure command generating unit (31) which generates a reference welding pressure command for a spot welding gun by applying pressure to workpieces to be welded between two electrode tips and at least one detective welding pressure command, an elastic displacement quantity deviation calculating unit (32) calculating, as an elastic displacement quantity deviation, a rotational position deviation between the rotational position of a servomotor when the reference welding pressure command is used and the rotational position of the servomotor when at least one detective welding pressure command is used, and an estimating unit (34) which estimates that there is an abnormality in the spot welding gun when the deviation between the elastic displacement quantity deviation based on the reference welding pressure command and at least one detective welding pressure command and the reference displacement quantity deviation is greater than a predetermined value.
US09440303B2 Heat processing device
A reflow furnace (1) has a decompression chamber (5), and air bubbles contained in a molten solder on a substrate (7) are removed in this decompression chamber (5). The substrate (7) supported on a first conveying rail (8) is fed into the decompression chamber (5) by a first conveyance rod (18). The substrate (7) in the decompression chamber (5) is taken out by a second conveyance rod (32) and is conveyed to the exit of the reflow furnace (1) while being supported on the second conveying rail (9). Before the treatment of substrates (7) having different widths, the width of the first conveying rail (8) and the width of the second conveying rail (9) are adjusted. During this adjustment, the second conveyance rod (32) is displaced in the width direction of the substrate (7), with the second conveyance rod (32) kept in the decompression chamber (5), and in association with this, the spacing between right and left rail portions (12a, 12a) in the decompression chamber (5) is adjusted.
US09440301B2 Sinker electric discharge machining apparatus
A sinker electric discharge machining apparatus includes a quill 10, to which a tool electrode is attached, and a linear motor device configured to generate a linear movement of the quill towards a workpiece. The quill includes a plate member 11 made of a metal or an alloy, a first reinforcing member 51 fixed to a front surface 14 of the plate member, a second reinforcing member 52 fixed to the front surface of the plate member, a third reinforcing member 53 fixed to a back surface 15 of the plate member and disposed opposite to the first reinforcing member across the plate member, and a fourth reinforcing member 54 fixed to the back surface of the plate member and disposed opposite to the second reinforcing member across the plate member. The quill has a cross-section that is symmetric in a width direction of the plate member.
US09440299B2 Method of manufacturing multiple identical gears using a gear cutting machine
The invention relates to method of manufacturing a multiple of identical gears by means of cutting machining, in particular hob cutting or hob grinding, on a gear-cutting machine, wherein workpieces are machined by means of a rotating tool which is brought into engagement with the workpiece via the control of NC axes of the gear cutting machine. In accordance with the invention, deviations from workpiece to workpiece are compensated by a respective different control of at least one of the NC axes of the gear cutting machine.
US09440294B2 Modular cutting insert and method of making same
A cutting insert for use on a tool body includes a first member formed in a predetermined shape and a second member formed separate from the first member in a second predetermined shape and coupled to the first member. At least one of the first member or the second member comprise a number of cutting portions adapted to perform cutting operations on a workpiece.
US09440287B2 Coatings for high temperature components
A method for forming a coating on a substrate is provided. To an assembly 10 including a substrate 12, a porous matrix 14 on the substrate 12, and an impregnating material 16 on or within the porous matrix 14, the method includes applying an amount of energy 18 from an energy source 20 effective to melt the impregnating material 16 and a portion of the substrate. In this way, the impregnating material 16 impregnates the porous matrix 14. The method further includes cooling the assembly 10 to provide a coating 26 comprising the porous matrix 14 integrated with the substrate 12.
US09440285B2 Device for forming thin films and method for using such a device
The invention relates to a device for forming at least one thin film made of a powder material (14). The device includes a storage area, a deposition area (7), and a cylinder (1) having a circular base for depositing and compacting the powder material (14), the latter having been previously moved from a storage area to a deposition area (7). The device further includes a cylinder (1) having a smooth cylindrical surface, said cylinder being rotatably movable (F1) about the axis of revolution (A) thereof, as well as translatably movable in at least one direction (F5) parallel to a main plane in the deposition area (7), between the storage and deposition (7) areas; a scraper (3) that is movable in a direction perpendicular to the main plane of the deposition (7) area, as well as translatably movable in the same direction (F5) as the cylinder (1), between the storage and deposition (7) areas, the scraper (3) being adapted to move the powder material from one area to another (7).
US09440284B2 Riveting tool and method with electromagnetic bucking bar normalization
A riveting tool including a magnet, a magnetically attractive housing, a non-magnetically attractive bucking bar received in the housing, the bucking bar being moveable relative to the housing along a bucking bar axis, and an actuation mechanism to move the bucking bar along the bucking bar axis.
US09440275B2 Spring means for device for working sheet-like material
The invention relates to a device for working sheet-like material, such as a press brake for bending steel sheet. The device includes: a frame; two, relative to each other movable, substantially parallel beams for working the sheet-like material, which beams are connected to the frame; driving means for driving the substantially parallel beams away or towards each other; at least one spring means, connected at a horizontal position along said beams for urging the beams away from each other; wherein the spring means have a spring constant that is adjustable.
US09440268B2 Apparatus for laying and anchoring a sheet of material on a ground surface
A machine (20) for laying a film (122) on a ground surface such as a landfill has a pair of opposed, support arms (84) each having a respective film roll support mechanism (94). In some embodiments the support arms are pivotable. Each film roll support mechanism (94) has a moveable arm (102) with a film roll support bracket (106), and a hydraulic system (98, 104) controllable by an operator of the machine for retracting and extending the moveable arm (102). The machine has means (120, 124) for holding the roll (96) of film between the brackets (106) for unwinding the film onto the ground. The machine may include a film cutter assembly (154) for cutting the laid film.
US09440266B2 Washer / disinfector having a water inlet diffuser
A washer having a plurality of water inlet diffusers, each diffuser connected to a water inlet line for directing the flow of fluid into the washing chamber. The water is directed, i.e., sprayed against the surfaces of the washing chamber to modify (adjust) the temperature of the washing chamber gradually prior to the start of a particular phase of a washing cycle.
US09440258B2 Thin film ultrasound transducer
The present invention relates to a transducer (11) comprising—a membrane (31) configured to change shape in response to a force, the membrane (31) having a first major surface (16) and a second major surface (17), —a piezoelectric layer (18) formed over the first major surface (16) of the membrane (31), the piezoelectric layer (18) having an active portion, —first and second electrodes (19) in contact with the piezoelectric layer (18), wherein an electric field between the first and second electrodes (19) determines the mechanical movement of the piezoelectric layer (18), —support structures (40) at the second major surface (17) of the membrane (15) on adjacent sides of the active portion of the piezoelectric layer (18), at least part of the support structures (40) forming walls perpendicular, or at least not parallel, to the second major surface (17) of the membrane (31), so as to form a trench (41) of any shape underlying the active portion, so that an ultrasound transducer is obtained with a high output pressure at the support side than at the opposite side. The invention also relates to a method of forming such a transducer, and an array comprising at least one transducer of the like.
US09440257B2 Method of coating an element with glue
The invention relates to a method for producing a glue-coated element, to the glue-coated element, to an adhesive compound and to a method for producing glue-coated derived timber panels, as well as to panels produced according to the method. The method for producing a glue-coated element that can be glued with other similarly glue-coated elements, comprises the steps of applying a one-component adhesive to at least one surface section of the element and drying the applied one-component adhesive. According to a preferred embodiment of the invention, draw-out resistance elements are provided on the glue-covered element.
US09440256B2 Method for producing laminate including metallic ink layer
A laminate is provided that includes a metallic ink layer having excellent glossiness. A method for producing a laminate includes forming a metallic ink layer by irradiating ultraviolet light to a metallic ink applied onto a medium, forming a smoothing ink layer by applying a smoothing ink onto the metallic ink layer after forming the metallic ink layer, and forming a color ink layer by applying a color ink onto the smoothing ink layer.
US09440251B2 Apparatus for producing reconfigurable walls of water
The present invention is directed to an apparatus for producing a water maze from walls of falling water that can be reconfigured to change the maze. In one embodiment, the apparatus is comprised of a plurality of spray bars that are each capable of producing a separate wall of falling water droplets and a plurality of water valves that are each associated with only one spray bar. The water valves can be used to define at least two different paths between the entrance and exit of the maze. The apparatus is also capable of being used to create interesting visual effects by projecting light/images on to multiple screens created by walls of falling water droplets.
US09440248B2 Fluid dispenser device
The invention relates to a fluid dispenser device, comprising: a body for mounting in stationary manner on the fluid reservoir; an actuator rod that is moved axially down and up inside the body; and a pusher that is mounted on the actuator rod by connection means including magnetizing means so as to generate a connection, by magnetic attraction, between the actuator rod and the pusher. The connection means comprises a rod organ engaged around the actuator rod and a pusher organ secured to the pusher, the actuator rod defining an internal fluid duct. The pusher forming a connection sleeve defining an internal fluid channel that leads to a dispenser orifice. The rod organ is deformed by the connection sleeve of the pusher, thus joining the duct to the channel in leaktight manner.
US09440244B2 Fiber reinforced porous metal centrifuge rotor
The present invention relates to a centrifuge rotor, in particular a laboratory centrifuge rotor, including a rotor body, wherein the rotor body at least partially includes a porous metal or a porous metal alloy and an armoring located radially outside with respect to the rotation axis of the rotor body is provided.
US09440243B2 Apparatus for centrifugation and methods therefore
A centrifuge vessel is configured to have at least two chambers therein separated by a divider, and with a spillway around a lip at an end of the divider to join the chambers. After centrifugation differing density phases of an original sample remain on opposite sides of the divider. Separate extraction ports are provided for removal of differing density phases of the original sample from opposite sides of the divider. A method of use of the centrifuge vessel includes centrifugation and extraction at differing orientations of the vessel for convenient and reliable extraction of differing density fractions from the original sample.
US09440242B2 Frothers for mineral flotation
The invention provides methods and compositions for improving a froth flotation type separation. The method uses a microemulsion to improve the effectiveness of a frother. The improvement allows for low dosages of frother to work as well as much greater amounts of non-microemulsified frother.
US09440238B2 Shredder with media detector
A shredder includes a housing having an opening for the insertion of media to be shredded. A cutting assembly for the shredding of media is disposed in the housing. A media detector including an infrared emitter and an infrared sensor is disposed about the opening for the detection of the presence of media to be shredded in the opening. A controller is disposed in the housing and is in responsive communication with the media detector for controlling the operation of the cutting assembly. The controller is programmed with a dynamic media detection threshold that is at least in part passed upon an emission sensed value and a background sensed value.
US09440235B2 Genetic testing method and testing apparatus
A genetic testing method and an apparatus therefor are provided, in which temperatures of a plurality of reaction tubes are independently controlled using a thermostat, a temperature detecting device, and a heating and cooling device provided on each of the reaction tubes, the reaction tubes each accommodate an amplification liquid and a component necessary for amplification, temperature is controlled at individual positions to hold the reaction tubes and at a predetermined temperature set at the individual positions according to an analysis and testing protocol predetermined at individual positions of the reaction tubes, a controlled temperature value is monitored in a reaction tube unit and a corrected value of controlled temperature is computed and stored on a reaction tube unit, a temperature of the reaction tube is controlled based on the computed value, and light emission of the amplification liquid accommodated in the reaction tube is measured.
US09440233B2 Microfluidic device for serial fluidic operations
An integrated microfluidic device for carrying out a series of fluidic operations includes a housing including a plurality of n microfluidic conduits, wherein n is at least three, and a rotating valve having an internal channel with an entrance port and an exit port that are angularly separated. The rotating valve is positionable in a first position to connect two of the n fluidic conduits via the internal channel, and upon rotating the valve to a second position, two other of the n fluidic conduits are connected by the internal channel. The device further may include one or more fluidic chambers in fluid communication with respective fluidic conduits. Fluid contained in one fluidic chamber is transferrable by application of positive or negative gas pressure through associated fluidic conduits into another fluidic chamber via the internal channel. The device may be utilized to perform a variety of fluidic operations.
US09440232B2 Manipulation of fluids and reactions in microfluidic systems
Microfluidic structures and methods for manipulating fluids and reactions are provided. Such structures and methods may involve positioning fluid samples, e.g., in the form of droplets, in a carrier fluid (e.g., an oil, which may be immiscible with the fluid sample) in predetermined regions in a microfluidic network. In some embodiments, positioning of the droplets can take place in the order in which they are introduced into the microfluidic network (e.g., sequentially) without significant physical contact between the droplets. Because of the little or no contact between the droplets, there may be little or no coalescence between the droplets. Accordingly, in some such embodiments, surfactants are not required in either the fluid sample or the carrier fluid to prevent coalescence of the droplets. Structures and methods described herein also enable droplets to be removed sequentially from the predetermined regions.
US09440231B2 Polymer microfluidic biochip fabrication
Provided are microfluidic devices and methods for fabricating and bonding such devices. Also provided are kits for analyzing analyte-containing samples and for lysing cells.
US09440226B2 Method for preparing methyl acetate
The present invention provides a method for preparing methyl acetate, in which a feed gas containing an organic amine, dimethyl ether, carbon monoxide and optional hydrogen gas goes through a reactor loaded with a H-type mordenite catalyst, to produce methyl acetate; wherein said H-type mordenite catalyst is a H-type mordenite catalyst with adsorption of an organic amine. The method in the present invention improves the catalyst stability and prolongs the catalyst life, by using the H-type mordenite catalyst with adsorption of an organic amine as the catalyst and adding the organic amine in the feed gas to replenish the organic amine desorbed from the catalyst during the reaction.
US09440218B2 Methods and active materials for reducing halide concentration in gas streams
The present disclosure relates generally to methods and active materials for purifying gas streams containing halide as a contaminant, for example, in amounts as low as parts-per-million (ppm) or even parts-per-billion (ppb). In one aspect of the invention, an active material includes (a) one or more first metals each present as a metal oxide or metal hydroxide, the first metals being selected from the group consisting of iron, cobalt, nickel, copper, ruthenium, rhodium, palladium, silver, osmium, iridium, platinum, and gold; and (b) one or more second metals each present as a metal oxide or metal hydroxide, the one or more second metals being selected from the group consisting of alkali metals, alkaline earth metals, scandium, yttrium, titanium, zirconium, hafnium, vanadium, niobium, tantalum, chromium, molybdenum, tungsten, manganese, technetium, and rhenium.
US09440216B2 Minimal surface area mass and heat transfer packing
Mass transfer packing with a minimal surface or a triply periodic minimal surface which enables significantly improved performance for separation and mixing applications particularly with respect to distillation, liquid-liquid contacting, and heat exchange applications.
US09440212B2 Integrated cyclone assembly
Integrated primary and secondary cyclone assembly includes a secondary cyclone having an outlet tube extending therefrom and a primary cyclone operatively coupled with the secondary cyclone. The outlet tube has a cross dimension and length and is configured to be secured to a pressure vessel closure head to support the secondary cyclone therefrom. The primary cyclone has a tubular support member extending therefrom. The tubular support member is aligned substantially parallel with and has a length similar to the outlet tube of the secondary cyclone and is configured to be joined to the pressure vessel closure head to support the primary cyclone therefrom.
US09440197B2 Crosslinked thermally rearranged poly(benzoxazole-co-imide), gas separation membranes comprising the same and preparation method thereof
Provided is a crosslinked thermally rearranged poly(benzoxazole-co-imide) obtained through the transesterification crosslinking of an ortho-hydroxy polyimide copolymer and a diol compound, followed by thermal rearrangement, a gas separation membrane (excluding a membrane for flue gas separation), and a method for preparing the same. The crosslinked thermally rearranged poly(benzoxazole-co-imide) according to the present invention allows less packing of polymer chains and has a structure with a larger space, and thus shows increased possibility of permeation and diffusion of small molecules therethrough. In addition, the gas separation membrane (with the proviso that a membrane for use in flue gas separation is excluded) including the crosslinked thermally rearranged poly(benzoxazole-co-imide) according to the present invention has excellent gas permeability and selectivity, and particularly shows gas separation quality in terms of carbon dioxide/methane separation corresponding to a level exceeding the so-called 2008 upper bound.
US09440195B2 Biomimetic membrane formed from a vesicle-thread conjugate
The present invention relates to a method for producing man-made devices which have the properties and functions of biological membranes and membrane proteins, and to the structure of such devices.Briefly, in one aspect of the invention, natural or genetically engineered proteins are incorporated into a polymeric vesicle that is conjugated to a thread to form a vesicle-thread conjugate. The engineered protein is preferably a transmembrane protein embedded in the wall of the polymeric vesicle. The vesicle-thread conjugate is then formed into a membrane or thin fabric having a wide variety of inherent functionality, including the ability to selectively transport and/or filter compounds between fluids. By selecting proteins with specific properties, membranes can be fabricated with a defined functionality including molecular scale addressability via directed electrostatic, electromagnetic, and chemical forces.
US09440194B2 Exhaust gas purification apparatus for an internal combustion engine
A decrease in the NOx removal or reduction rate is suppressed, while suppressing the outflow of particulate matter from a filter after regeneration of the filter. To this end, in an exhaust passage of an internal combustion engine, there are provided a filter, an NOx storage reduction catalyst, and an NOx selective reduction catalyst which is arranged at the downstream side of the NOx storage reduction catalyst, wherein when a reducing agent is supplied to the NOx storage reduction catalyst or the NOx selective reduction catalyst, rich control in which an air fuel ratio of exhaust gas is controlled to a rich air fuel ratio is carried out, and the lowest value of the air fuel ratio of the exhaust gas, at the time of carrying out the rich control in a predetermined period of time from a point in time at which the regeneration of the filter has ended, is made higher than the lowest value or an average value of the air fuel ratio of the exhaust gas at the time of carrying out the rich control in a period of time from the lapse of the predetermined period of time until when the next regeneration of the filter is carried out.
US09440193B2 Urea spray selective catalytic reduction control system
A urea spray selective catalytic reduction (“SCR”) control system includes an SCR catalyst provided in a discharge pipe of an engine, a dosing valve for injecting urea water at an upstream side of the SCR catalyst, and NOx sensors, wherein the system controls injection of the urea water from the dosing valve. The system includes a plurality of NOx model maps corresponding to an atmospheric pressure condition, an outdoor air temperature, and an engine water temperature, and determines an amount of NOx from each NOx model map on a basis of detection values of an atmospheric pressure detector, an outdoor air temperature detector, and an engine water temperature detector, and controls an amount of injection of the urea water from the dosing valve on a basis of the amount of NOx thus determined.
US09440192B2 Diesel oxidation catalyst and use thereof in diesel and advanced combustion diesel engine systems
An oxidation catalyst composite, methods and systems for the treatment of exhaust gas emissions from an advanced combustion engine, such as the oxidation of unburned hydrocarbons (HC), and carbon monoxide (CO) and the reduction of nitrogen oxides (NOx) from a diesel engine and an advanced combustion diesel engine are disclosed. More particularly, washcoat compositions are disclosed comprising at least two washcoat layers, a first washcoat comprising a palladium component and a first support containing cerium and a second washcoat containing platinum and one or more molecular sieves.
US09440188B2 Method for removing contaminants from exhaust gases
An exhaust gas stream from a combustion process is conveyed through a gas distributor at an inlet of a wet horizontal spray scrubber where it is partitioned into a plurality of spaced apart gas streams. The gas stream is partitioned in the scrubber without the need for any physical partitions. A preselected number of the partitioned gas streams are mixed with ozone to oxidize the contaminants. The oxidized gas streams are then sprayed with an aqueous medium to capture the oxidized contaminants and remove them from the treated gas streams. The treated gas streams are then recombined with the untreated gas streams. Excess ozone present in the treated gas streams is consumed by oxidation of contaminants in the untreated gas streams before the combined gas stream is released to the atmosphere.
US09440184B2 Apparatus for removing air contaminants
The present invention relates to an apparatus for removing air contaminants, which adsorbs dust and harmful substances contained in the air contaminants using an absorbing unit connected to an inlet pipe inserted in a tank.
US09440183B2 Method of controlling a wet scrubber useful for removing sulphur dioxide from a process gas
A wet scrubber (1) for cleaning a process gas containing sulphur dioxide comprises an absorption vessel (2) for contacting the process gas with an absorption liquid to absorb sulphur dioxide from the process gas, a sulphite sensor (68, 74) for measuring a sulphite concentration in the absorption liquid, and a control unit (52). The control unit (52) is adapted to receive a measurement signal from the sulphite sensor (68, 74) and to control, based on the measured sulphite concentration, at least one wet scrubber operating parameter influencing the sulphite concentration in the absorption liquid.
US09440178B2 Pleated filter media
A filter element includes a center tube and a blank of a filter media. The center tube has a first end and a second end. The blank is folded into a plurality of triangles. Each triangle is disposed adjacent to another of the plurality of triangles to form a series of triangular pleats to form a pleated filter media. The pleated filter media is disposed about the center tube. A cross sectional area of the pleated filter media proximal to each of the first end and the second end is greater than a cross sectional area of the pleated filter media at a point between the first end and the second end.
US09440177B2 Crankcase ventilation filter systems; components; features; and, methods of assembly and use
Crankcase ventilation filter assemblies are described and shown. Components, features and methods of assembly and use are described. Many of the principles relate to preferred cartridge configurations for engagement with selected housings. Selected optional features described can be used to provide indication to a service provider that a proper cartridge is not positioned appropriately in the housing for use.
US09440169B2 Fuel filtration system, filter exchange module therefor, and method of replacing fuel filters
A fuel filtration system includes an electric pump, a filter assembly, and conduits for fluidly connecting the pump and filter assembly in series with a fuel tank to define a kidney filtration loop. The filter assembly includes a filter assembly head, including attachment openings therethrough, and a filter exchange module, including a mounting plate having externally threaded mounting connectors extending outwardly from one face thereof and internally threaded bores opening through another face thereof. In a mounted configuration, a fuel filter is threaded onto each mounting connector such that the filter is fluidly aligned with a fuel flow opening through the mounting plate, fasteners are positioned through the attachment openings and threadably received within the bores, and fuel flow passages of the filter assembly head define a flow distribution in which one pair of filters is fluidly in parallel and another pair of filters is fluidly in series.
US09440164B2 System and method for water treatment
System and method of treating waste water includes: receiving waste water at a first pressure and temperature, the waste water comprising dissolved solids and VOCs; pressurizing, by a pump, the received waste water to a second pressure greater than the first pressure; preheating, by a preheater, the waste water to a second temperature greater than the first temperature producing distilled water; further heating, by a condenser, the pressurized/preheated waste water to a fourth temperature greater than the second temperature; still further heating, by a heater, the pressurized/further heated waste water to a third temperature greater than the fourth temperature; and removing, by a flash evaporator, dissolved solids from the pressurized/heated waste water by evaporation producing steam and brine water, the brine water having a TDS content greater than a TDS content of the received waste water. The brine water may be crystallized to a solid mass.
US09440162B2 System and method for water treatment
A system and method for treating waste water includes: receiving waste water at a first pressure and a first temperature, the waste water including dissolved solids and volatile organic compounds; pressurizing, by a pump, the received waste water to a second pressure greater than the first pressure; preheating, by a preheater, the pressurized waste water to produce distilled water and a pressurized/preheated waste water; heating, by a heater, the pressurized/preheated waste water to a second temperature greater than the first temperature to produce pressurized/heated waste water; removing, by a flash evaporator, dissolved solids from the pressurized/heated waste water by evaporation to produce steam and brine water, wherein the brine water has a total dissolved solids content greater than a total dissolved solids content of the received waste water; and crystallizing, by a plasma crystallizer, the brine water to produce a solid mass of waste product and steam.
US09440160B1 Wave simulating apparatus
The invention features an event wave simulating apparatus used at an event, concert or performance etc. by spectators, fans, etc. to show their enthusiasm and/or support for the event. Users may express their enthusiasm or support by simulating a wave when the apparatus is waved. The apparatus includes a first section which is connected with a second section which includes a closed enclosure. The apparatus also includes two sleeves within the first section, where each sleeve is configured to receive a user's arms and where the sleeves extend into the first section.
US09440156B2 Flying roller coaster with vertical load and launch
A method of operating a ride system to provide passengers a flying roller coaster experience. The ride system includes a train of vehicles, with each of the vehicles including seat assemblies that have a seat and seat back for receiving a passenger. The vehicles are supported by the track to roll along the track, and the ride path is adapted for gravity-based movement of the train of vehicles in at least portions of the ride path. The track includes a vertical segment, and the ride system includes a station including a platform assembly with horizontal platforms vertically spaced-apart to provide multi-level loading. The train is positioned on the vertical segment with each of the vehicles proximate to an end of one of the horizontal platforms. The seat backs are substantially parallel to a longitudinal axis of the track to provide vertical loading and, then, vertical launching from the station.
US09440150B2 Game device
A game device includes: a first requirement achievement determining unit operative to determine whether or not a requirement of gameplay predefined in a game is achieved based on a progress status of the game; a second requirement achievement determining unit operative to determine whether or not a result of determination by the first requirement achievement determining unit meets a predetermined condition; a display processing unit operative to display information related to the requirement of gameplay determined by the first requirement achievement determining unit as being achieved, and information related to the predetermined condition determined by the second requirement achievement determining unit as being met, where the first requirement achievement determining unit is implemented by game software and the second requirement achievement determining unit is implemented by system software.
US09440146B1 Managing location-based meta games
In a method of managing a location-based meta game, a presence of a device is detected at a location. The device is configured to execute a computer-implemented game. Based on the detecting of the presence of the device, the device is instructed to present a user of the computer-implemented game with an option to participate in a computer-implemented meta game associated with the location.
US09440142B2 Blocking mechanism for amusement game with multiple lifting pins
A blocking mechanism for a table-type amusement game, and a table-type amusement game equipped with a blocking mechanism. The blocking mechanism utilizes a series of blocking pins goes from a closed position, which blocks a playing piece from scoring to an upper open position, which permits the playing piece to score. The blocking mechanism may be manually or electrically operated. When the blocking mechanism is electrically operated, it may be activated by the insertion of a coin into a coin and/or bill acceptor of the type found on table-type amusement games.
US09440140B1 War game using cards and dice
The war game using cards and dice includes a plurality of game cards having a distinct first subset of game cards including a plurality of Soldier game cards, a plurality of Base game cards, and a plurality of Supply game cards, a distinct second subset of game cards including a plurality of Area game cards, a distinct third subset of game cards including a plurality of Action game cards, and at least one dice. The goal of the game is to acquire two sets of “Area” cards. Each Area card is identified by an Area name, a corresponding Area flag, a numerical value, and a group area designation as discussed further below. A “set” of Area cards includes three Area cards having the same area name and/or flag. The game can further require that the two sets be in the same group area.
US09440139B1 Method of playing a bonus
A method of playing a game bonus triggered by the rank of the player hand. In a first embodiment, a number of bonus hands is displayed, each assigned a bonus value. A number of bonus hands are chosen, the number chosen being dependent on the rank of the player hand. The values of the chosen bonus hands are revealed. Alternatively, a number of bonus hands is displayed, the number being dependent on the rank of the player hand. After the bonus values are revealed, the player is paid an amount based on the bonus values.
US09440137B2 Toe-piece for ski-touring bindings
A toe-piece for ski-touring bindings includes a base plate coupled to two jaws. The base plate provided with holes for fixing by screws to the surface of a ski extending in the longitudinal direction from a front tip to a rear tail-end. The two jaws situated opposite each other and symmetrically with respect to a longitudinal axis. Each of the two jaws having a transverse arm and a vertical arm provided with a respective transverse conical pin, which arms are configured to rotate about an axis substantially parallel to the base plate and to the longitudinal direction between a closed and/or open position for retaining and/or inserting and releasing the toe of a ski-boot and an open and/or closed position for releasing and inserting and/or retaining the toe.
US09440136B2 Goal tender leg pad
A goaltender leg pad providing profile adjustment, toe attachment and/or toe thickness adjustment. The leg pad can include an adjuster element that configures adjacent pads at a user selected angle or configuration to provide a desired front profile of the leg pad. The leg pad can include an optionally elastic toe attachment strap joined with a foot pad and/or boot, and a redirection element slidably engaging the strap. The strap can secure the foot pad to the user's skate, and generally centrally locate the foot pad over the user's skate when the user transitions to a standing position and/or a crouching position. The leg pad can include a foot pad configured to engage the top of a user's skate. The foot pad can define a cavity within which a secondary pad can be selectively installed or removed to alter the toe thickness of the foot pad and provide desired performance.
US09440131B2 Sports training device
A device for training a baseball/softball player to swing a bat with a positioning apparatus affixed to the bat and a guide component tethered to an adjustable cuff on the upper arm of the trailing arm. Interconnection of guide component and positioning apparatus prevents the hands and bat from casting away from torso through midpoint in the swing and Prevents barrel of the bat from preceding knob end of the bat prior to the point of contact with ball. Positioning apparatus disengages from guide component prior to point of contact with ball allowing player to complete the swing.
US09440130B2 Shuttlecock and manufacturing method thereof
A shuttlecock includes: a set of feather units, a shuttlecock head, and a connecting arrangement which including a feather planting arrangement. The feather planting arrangement includes a set of feather planting members of the same number as the number of the feather units, each feather planting member has a feather planting end portion and an insertion end portion, a shaft member of each feather unit is inserted in the feather planting end portion while the insertion end portion of each feather planting member is inserted in the shuttlecock head. Further disclosed is a method of manufacturing the shuttlecock.
US09440129B2 Animal shaped golf bag
An animal-shaped golf bag is a golf bag that houses, transports, and protects golf clubs and additional items. In addition to maintaining the original functionality of a golf bag, the animal-shaped golf bag additionally provides the aesthetic appearance of an animal. The animal-shaped golf bag features a main animal-shaped body with a club-receiving cavity for storing golf clubs. A rigid base is provided for stability when resting on a surface. A plurality of animal feature-shaped pockets is also present for storing the user's items and providing the aesthetic appearance of an animal. Additionally, the animal-shaped golf bag features a plurality of aesthetic ornaments and a plurality of aesthetic displays that further enhance the aesthetic appearance of an animal provided by the animal-shaped golf bag. The animal-shaped golf bag may be conveniently transported by means of a carry handle and a carry strap.
US09440127B2 Golf clubs and golf club heads
Golf clubs according to at least some example aspects of this disclosure may include a golf club head and a shaft configured to engage with the golf club head which includes a grip engaged with the shaft. Further, the golf club may include a monitoring device, which includes a sensor and a transmitter. Additionally, the monitoring device may be configured to determine data related to the characteristics of a golf swing. Further, the monitoring device may be configured to transmit the data related to the characteristics of a golf swing to a remote computer.
US09440122B2 Golf clubs and golf club head structures having contoured backstop
Golf club and golf club head structures include an inner wall or backstop arranged behind a ball striking surface of the golf club head and defining a gap between the inner wall and a rear surface of the ball striking surface. In some arrangements, the size of the gap may vary along a heel-to-toe length of the inner wall or backstop. For instance, the size of the gap may gradually increase from a first end of the inner wall toward a central region of the inner wall, and may gradually decrease from the central region toward a second end of the inner wall. In some examples, the inner wall or backstop may be connected to the golf club head, for instance, at a first end and/or a second end.
US09440121B2 Coated golf club head/component
A golf club component, such as a golf club head and/or a golf club shaft, can comprise a golf club component substrate having an outer layer of titanium carbide, typically comprising at least forty percent (40%) carbon content. Alternatively, a golf club component can comprise a golf club component substrate, at least a portion of which is enveloped by a first coating layer of, for example, electroplated nickel, a second coating layer of, for example, electroplated chromium or palladium, and a third coating layer of titanium carbide applied by physical vapor deposition. The titanium carbide layer is durable and can provide the golf club component with a desired aesthetic appearance, such as a black color. Additionally, the golf club component can be coated with a fourth coating layer, such as a layer comprising a sealant or clear coat material.
US09440115B2 Dimple patterns for golf balls
The present invention provides a method for arranging dimples on a golf ball surface in which the dimples are arranged in a pattern derived from at least one irregular domain generated from a regular or non-regular polyhedron. The method includes choosing control points of a polyhedron, generating an irregular domain based on those control points, packing the irregular domain with dimples, and tessellating the irregular domain to cover the surface of the golf ball. The control points include the center of a polyhedral face, a vertex of the polyhedron, a midpoint or other point on an edge of the polyhedron and others. The method ensures that the symmetry of the underlying polyhedron is preserved while minimizing or eliminating great circles due to parting lines.
US09440113B2 Cardio-based exercise systems with visual feedback on exercise programs
In general, a computing device disposed in a cardio exercise machine receives data related to a fitness level of a user. The computing device selects a workout program based at least in part on the data. The operations of the cardio exercise machine are controlled based at least in part on the workout program. The computing device generates visual feedback based on at least one of the user's operation of the cardio exercise machine and the selected workout program measured against performance criteria.
US09440106B2 Apparatus for positioning a component of an exercise device
An exercise device including at least one positionable component configured to be positioned by a user. The exercise device includes a frame to which a collar is mounted. The positionable component includes a member that is slidably received within the collar and may be positioned by sliding the member to a selected position. A locking assembly is coupled to the collar and is operable to lock the member in a selected position within the collar, to release the member from the locked position, and when released, to allow the member to slide within the collar. The locking assembly includes a cam pivotably mounted to the collar and a cam follower assembly selectively biased by the cam against a portion of the member disposed inside the collar. The locking assembly also includes a pair of engagement members disposed inside the collar opposite the cam against which the cam biases the member.
US09440101B2 Flame dispersant canister mounting system for under-microwave location
A fire extinguisher apparatus and related system is described for automatically suppressing stovetop fires. The fire extinguisher apparatus includes a canister restrained in a first location where the canister is operable to suppress fires on a rear burner of a stovetop. The canister is biased and movable to a second location where the canister is operable to suppress fires on a front burner of the stovetop. A trigger mechanism is provided for automatically moving the canister to the second location in response to a fire on the front burner. The fire extinguisher system includes an arrangement of fire extinguisher apparatuses wherein canisters are movable between the apparatuses to prevent collisions with external obstacles.
US09440100B2 Fire and/or smoke blocking device
A fire door assembly is provided for covering a structure opening in a sidewall of a structure. The fire door assembly has a roller assembly to be mounted to a portion of the structure defining a portion of the structure opening and a curtain panel disposed on the roller assembly. The curtain panel is operable between a retracted position where the curtain panel is wound onto the roller assembly and an extended position where the curtain panel is unwound from the roller assembly to cover the structure opening. The curtain panel includes first and second panel portions with mutually opposing edge portions in a closed position. A fastener is provided to releasably attach the first and second panel portions to each other. The first and second panel portions are separable from each other in response to an egress force exerted thereon to form an egress through the curtain panel. Upon relaxation or removal of the egress force, the panel portions return to the closed position to close the egress.
US09440093B2 More dermal retraction with intersecting electromagnetic radiation pathways
A method and device for stimulating human dermal tissue retraction and collagen and elastin production is provided. One or more lasers or other electromagnetic radiation devices produce at least two output beams (split or independent beams) that can be directed to deliver electromagnetic energy to a desired subsurface depth of dermal tissue, thereby disrupting the same, without causing excessive damage to the adjacent epidermis, subcutaneous fatty tissue, or blood vessels of the skin.
US09440089B2 Apparatus and method for electromagnetic treatment of neurological injury or condition caused by a stroke
Described herein are methods of treating neurological injury and conditions, in particular symptoms and complications arising from or caused by a stroke. These treatment methods can include the steps of generating a pulsed electromagnetic field from a pulsed electromagnetic field source and applying the pulsed electromagnetic field in proximity to a target region.
US09440088B2 Implanted lead analysis system and method
The technology disclosed herein relates to a method for lead analysis for an implanted medical device. A summary data record is retrieved associated with one or more episodes from an implanted medical device through a communication module. Episode selection criteria are applied to the summary data record by a processing module. One or more episode data records are retrieved from the implanted medical device for one or more episodes for which the episode selection criteria was satisfied. Noise detection criteria are applied to the episode data record. A notification module is configured to generate an alert if the noise detection criteria are satisfied.
US09440087B2 AED with alternate shock switch
A semi-automated AED with a second shock switch. In an illustrative embodiment, programming running on the AED after prompting a user of the AED to push a shock switch looks to see if an event associated with pushing the shock switch, such as the delivery of a shock, has occurred. If the event being monitored for has not occurred within a given time, the user is prompted to push another button to initiate the event.
US09440086B2 Optimized flash memory device for miniaturized devices
An implantable medical device have an associated memory device is disclosed. The implantable medical device utilizes techniques for optimizing one or more embedded operations of the memory device, such operations including programming, reading or erasing data. The techniques for optimizing the embedded operations include controlling the operations as a function of an energy source of the implantable medical device.
US09440082B2 Microfabricated neurostimulation device
Described herein are microelectrode array devices, and methods of fabrication and use of the same, to provide highly localized and efficient electrical stimulation of a neurological target. The device includes multiple microelectrode elements arranged along an elongated probe shaft. The microelectrode elements are dimensioned and shaped so as to target individual neurons, groups of neurons, and neural tissue as may be located in an animal nervous system, such as deep within a human brain. Beneficially, the neurological probe can be used to facilitate location of the neurological target and remain implanted for long-term monitoring and/or stimulation.
US09440071B2 Systems and methods for facilitating binaural hearing by a cochlear implant patient
An exemplary system for facilitating binaural hearing by a cochlear implant patient includes 1) a spectral analysis facility configured to divide a first audio signal presented to a first ear of the patient and a second audio signal presented to a second ear of the patient into first and second sets of analysis channels, respectively, and 2) a processing facility configured to process acoustic content contained in a first analysis channel included in the first set of analysis channels and acoustic content contained in a second analysis channel included in the second set of analysis channels, mix the processed acoustic content contained in the first and second analysis channels, and direct a cochlear implant to apply electrical stimulation representative of the mixed acoustic content to the first ear by way of a stimulation channel that corresponds to the first analysis channel.
US09440070B2 Wearable transdermal electrical stimulation devices and methods of using them
Apparatuses (e.g., devices, systems), and methods for transdermal electrical stimulation (TES). Apparatuses described herein can be self-contained, lightweight, and wearable. The apparatus may include a primary unit (TES stimulator) and an electrode portion that includes a first transdermal electrode and a second transdermal electrode and mates with the TES stimulator. The first electrode and secondary electrode are placed at two locations on the skin of a user, for example on the head and/or neck of a user. Electrical stimulation driven between the two electrodes may induce a cognitive effect in a user of the device.
US09440068B2 Treating bacteria with electric fields
Cells that are in the process division are vulnerable to damage by AC electric fields that have specific frequency and field strength characteristics. The selective destruction of rapidly dividing cells can therefore be accomplished by imposing an AC electric field in a target region for extended periods of time at particular frequencies with particular filed strengths. Some of the cells that divide while the field is applied will be damaged, but the cells that do not divide will not be harmed. This selectively damages rapidly dividing cells like bacteria, but does not harm normal cells that are not dividing. Improved results can be obtained when the field is sequentially imposed in different directions.
US09440066B2 Systems and methods for making and using connector assemblies for implantable medical device systems
A lead extension for an electrical stimulation system includes a lead-extension body, terminals, and a connector. The connector includes a contact housing and a gasket housing. Multiple connector contacts are disposed in the contact housing and are coupled to the terminals. A retention member is disposed along one end of the contact housing and is receivable by a retention socket defined in the gasket housing. A deformable gasket is disposed in the retention socket. A lumen extends through the connector and is suitable for receiving an electrical stimulation lead. The received lead is retained in the lumen by using the retention member to compress the gasket along a longitudinal length of the connector. The longitudinal compression of the gasket causes a corresponding radial expansion of the gasket, which retains the electrical stimulation lead within the lumen.
US09440062B2 Medical site cover
A medical site cover for a needle-free intravenous connector having a septum area and external threads. The medical site cover includes an elastomeric cap having an opening to an inner cavity. The inner cavity includes a first chamber adapted for receiving and surrounding the connector and a second chamber located between the first chamber and a closed end of the cap. A compressible member formed of an absorbent material is located in the second chamber, wherein the compressible member is a sphere.
US09440057B2 Therapeutic applications of cold plasma
The present disclosure relates to methods of treating diseases and disorders comprising applying a therapeutically effective dose of cold plasma. In particular examples, the diseases and disorders include, but are not limited to, diseases and disorders of the skin, musculoskeletal, and immune systems.
US09440056B2 Device and method for dispensing a drug
A device for dispensing a topically administered drug has a spreader which is used to actuate a pump to release the drug and then to spread the drug on the skin and. The spreader is coupled to a lock that prevents it from actuating the pump after a number of drug doses have been dispensed. The pump can be actuated to release no more than the selected quantity of drug per day or actuation.
US09440054B2 Expandable transapical sheath and method of use
Disclosed is an expandable transluminal sheath, for introduction into the body while in a first, small cross-sectional area configuration, and subsequent expansion of at least a part of the distal end of the sheath to a second, enlarged cross-sectional configuration. The sheath is configured for use in the vascular system and has utility in the introduction and removal of implant delivery catheters. The access route is through the ventricular myocardium, more specifically at the left ventricular apex, into the aortic root. The distal end of the sheath is maintained in the first, low cross-sectional configuration during advancement to the arteries into the aorta. The distal end of the sheath is subsequently expanded using a radial dilatation device, which is removed prior to the introduction of implant delivery catheters. In an exemplary application, the sheath includes a supported proximal end, a supported distal end, and a collapsible center section. Certain configurations of the sheath are capable of being inserted in a first, small cross-sectional configuration, being expanded diametrically to a second, larger cross-sectional configuration, and then being reduced to a diametrically small size for removal.
US09440053B2 Needle tip protector assembly for safety IV catheter assembly
The invention relates a safety IV catheter assembly comprising a catheter tube having a distal end and a proximal end; a catheter hub having a distal end and a proximal end; a needle extending through the catheter hub and the catheter tube having opposite proximal and distal ends defining an axial direction A, wherein the proximal end is joined to the needle hub and the distal end forms a needle tip and a change in profile is provided between the proximal and distal ends of the needle; and a tip protector assembly being arranged movably on the needle in-between the catheter hub and needle hub outside the catheter hub in an arrangement engaging with one or more second locking means provided on the catheter hub in its ready position, wherein the first arm is deflected radially outwards by the needle against a restoring force, wherein the tip protector assembly is configured to entrap the needle tip upon withdrawal of the needle from the catheter hub.
US09440050B2 Fluid infuser
A fluid infuser includes an introduction needle having a projection on a peripheral surface, and an infusion tube configured to cover the introduction needle. The projection of the introduction needle is installed at a position where the introduction needle comes into contact with the infusion tube, and includes a first surface and a second surface. The first surface is arranged at a picking end side of the introduction needle with respect to the second surface, and an angle of inclination of the first surface is larger than an angle of inclination of the second surface. The fluid infuser is configured to guide an infusion tube to an object of insertion adequately, and allow the introduction needle to be pulled out easily from the infusion tube.
US09440049B2 Apparatus and method for accessing a sinus cavity
A system for accessing a sinus cavity of a subject includes an access tool configured to penetrate into the sinus cavity from a location external the subject. The system further includes an access sheath having a distal tubular portion, a lumen extending through the access sheath and the distal tubular portion and dimensioned to receive the access tool, the distal tubular portion comprising one or more cutting surfaces disposed about an external surface thereof. The one or more cutting surfaces may include a plurality of longitudinally oriented grooves for flutes disposed about the periphery of the distal tubular member.
US09440046B2 Venous insufficiency treatment method
The method of treating varicose veins and other vascular diseases provides sclerosant fluid through a catheter into the body vessel to be treated. The catheter has a lumen and a plurality of sidewall exits. The sclerosant fluid is provided under sufficient pressure so that it comes out of each exit as a jet of fluid with sufficient velocity to impinge on the vessel wall substantially orthogonal to the wall and thus minimize dilution of the sclerosant fluid and optimize coverage. A movable sheath on the catheter permits selecting a portion of the exits to be uncovered and thus create an infusion zone for the jets of sclerosant fluid which approximately match a desired treatment zone.
US09440043B2 Catheter having a tapered structure and balloon formed above a lower drainage hole
A indwelling or Foley catheter is provided that has a tapered structure. In an aspect, the catheter includes an elongated cylindrical body having a proximal end configured to lie inside the bladder when inserted into the urinary tract and a distal end configured to extend outside the urinary tract, wherein an outer diameter of the proximal end is larger than an outer diameter of the distal end.
US09440041B1 Medicinal healing booth system
A medicinal healing booth system for treating a user with medicated steam features a booth. A side panel of the booth features a transparent or translucent top panel section from a panel midpoint to a roof panel. A base panel of the booth features raised grating. The system features a door located in the side panel of the booth. The system features a control system and a steam generation system having a water tank with a heating element, a medicine tank, and a steam distribution nozzle. The medicine tank is fluidly connected to steam piping having the steam distribution nozzle located on a terminating end. The system features a temperature regulation system having an infrared light, a vent, and an automated vent valve. The system features a sterilization system having an ultraviolet light. A seat is located on the booth base panel.
US09440039B2 Gas delivery device
A gas delivery device (1 or 101 or 201) having a substantially U-shaped nasal cavity component (3 or 103 or 203) that fits inside the patient's nostril is in fluid communication with a tubular guidance-stabilization system (8 or 108) that extends from the nasal cavity component (3 or 103 or 203), across the patient's cheek, and over the patient's ear. The tubular guidance-stabilization system (8 or 108) has a flexible wire or flexible strap that is embedded (or otherwise inserted) within the wall (33 or 120 or 220) of the tubular guidance-stabilization system (8 or 108) for the purpose of supporting the integrity of the gas delivery device (1 or 101 or 201) in order to maintain the tubular nasal cavity component (3 or 103 or 203) in the patient's nostril. A stabilization patch (17 or 18 or 118) further secures the tubular guidance-stabilization system (8 or 108) to the cheek and/or behind the ear of the patient.
US09440034B2 Drug condensation aerosols and kits
The present invention provides novel condensation aerosols for the treatment of disease and/or intermittent or acute conditions. These condensation aerosols have little or no pyrolysis degradation products and are characterized by having an MMAD of between 1-3 microns. These aerosols are made by rapidly heating a substrate coated with a thin film of drug having a thickness of between 0.05 and 20 μm, while passing a gas over the film, to form particles of a desirable particle size for inhalation. Kits comprising a drug and a device for producing a condensation aerosol are also provided. The device contained in the kit typically, has an element for heating the drug which is coated as a film on the substrate and contains a therapeutically effective dose of a drug when the drug is administered in aerosol form, and an element allowing the vapor to cool to form an aerosol. Also disclosed, are methods for using these aerosols and kits.
US09440032B2 Safety device for a pre-filled syringe and injection device
A safety device for a pre-filled syringe comprises a hollow support body to retain the pre-filled syringe, a retaining collar and a rotating collar arranged within the support body. The retaining collar is releasably mounted to the support body. The rotating collar is slidable along an axial length of the support body and rotatable around a central axis of the safety device. The retaining collar is movable with respect to the support body in a proximal direction when the retaining collar is released from being mounted to the support body by the rotating collar.
US09440022B2 Cassette with infusion set containing anti-freeflow ball valve for peristaltic infusion pump
Flow control devices and methods of using the flow control devices are provided. In a general embodiment, the present disclosure provides a cassette (30) comprising a housing (32) having a constrictor (34), a tube (36) attached to the housing and positioned through the constrictor, and a ball positioned inside the tube. The constrictor can be constructed and arranged to prevent the ball (38) from moving through the tube at the location proximate the constrictor. The ball can prevent fluid flow in one position and be dislodged to allow fluid flow when the cassette is positioned inside a pumping device. As a result, the cassette is designed to prevent free flow of fluid when an enteral feeding tube set is not installed in a pumping device.
US09440021B2 Removable controller for an infusion pump
Some embodiments of an infusion pump system include a controller device that is configured to removably attach to a pump device in a manner that provides a secure fitting, an overall compact size, and a reliable electrical connection. In particular embodiments, the controller device can be secured to the pump device in a generally side-by-side arrangement. The compact size can enhance the discreteness and portability of the infusion pump system.
US09440019B2 Sorbent for endotoxins
The invention relates to a sorption agent for removing endotoxins from a biological fluid, comprising a water-insoluble, porous carrier having a neutral hydrophobic surface wherein the surface of the carrier has an adsorptive coating made of polymyxin and albumin, wherein polymyxin and albumin are bonded to the surface of the carrier in a noncovalent manner. The invention further relates to a method for producing such a sorption agent. The sorption agent is used in extracorporeal blood purification, in particular in order to treat individuals, who have sepsis.
US09440014B2 Heart help device, system and method
The present invention relates to an implantable device for improving the pump function of the heart of a human patient by applying an external force on the heart muscle, said device comprising at least one pump device comprising: a first part having a first surface, and a second part having a second surface. The first part is displaceable in relation to the second part and said first and second surfaces abut each other, at least partially. The second part exerts, directly or indirectly, force on an external part of said heart muscle.
US09440010B2 Drape having microstrain inducing projections for treating a wound site
Systems and apparatuses for administering reduced pressure treatment to a tissue site include a reduced pressure source, a drape having a plurality of projections for contacting the tissue site, and an adhesive connected to at least a portion of the drape for sealing the drape to a portion of a patient's intact epidermis.
US09440007B2 Tissue scaffold
A tissue scaffold includes a first film having a plurality of cell openings and a second film adjacent the first film and having a plurality of cell openings larger than the cell openings of the first film. The cell openings of the first film interconnect with the cell openings of the second film to define pathways extending through the first and second films.
US09440006B2 Porous tissue scaffolds
A method for forming a porous tissue material.
US09440005B2 Substrate for feeding cells and/or tissues, cell/tissue-feeder and method for the production of the same, method for the regeneration of tissues, and method for the production of porous bodies
A substrate for feeding cells and/or tissues which is composed of a porous body having a thin film surface and a porous surface and which can be used in the regenerative medical techniques. A cell/tissue feeder is produced by cultivating tissues on the porous surface of the porous body. Cells are seeded on the porous surface of the body, followed by the cultivation of the cells to thus form and/or regenerate tissues. An aqueous solution of silk proteins, to which a water-soluble organic solvent is added, is introduced into a mold whose bottom or top surface is surface-roughened, followed by freezing the aqueous solution and then thawing the frozen aqueous solution to form a porous body having a thin film surface and a porous surface.
US09440000B2 Biocompatible phase invertible proteinaceous compositions and methods for making and using the same
Biocompatible phase invertible proteinaceous compositions and methods for making and using the same are provided. The subject phase invertible compositions are prepared by combining a crosslinker and a proteinaceous substrate. The proteinaceous substrate includes one or more proteins and a polyamine, where the polyamine and a proteinaceous substrate are present in synergistic viscosity enhancing amounts, and may also include one or more of: a carbohydrate, a tackifying agent, a plasticizer, or other modification agent. In certain embodiments, the crosslinker is a heat-treated dialdehyde, e.g., heat-treated glutaraldehyde. Also provided are kits for use in preparing the subject compositions. The subject compositions, kits and systems find use in a variety of different applications.
US09439996B2 Light source disinfection in a pneumatic transport system
Provided herein are systems, apparatuses and methods for use in disinfecting pneumatic tube system (PTS) components and/or disinfecting air displaced during the operation of a PTS. More specifically, various aspects are directed to the use of light source disinfection systems for disabling bacteria, viruses and/or other micro-organisms (hereafter “pathogens”) in a PTS. The light source disinfection systems allow of cleaning pneumatic carriers, cleaning the interior of pneumatic tubes and PTS components and/or cleaning air, which is used to propel pneumatic carriers in a PTS.
US09439993B2 Apparatus for delivering a volatile material
An apparatus for delivering a volatile material in a continuous manner is disclosed. The apparatus includes a delivery engine having a reservoir for containing a volatile material; a rupturable substrate secured to the reservoir; a rupture element positioned adjacent to the rupturable substrate; and a breathable membrane enclosing the reservoir, rupturable substrate and rupture element. In some embodiments, the apparatus includes a housing having a notch for compressing the rupture element and breaching the rupturable substrate as it is inserted into the housing.
US09439989B2 Disinfecting light fixture
Disclosed herein is a light fixture. The light fixture includes at least one first light source that emits at a peak wavelength in a range of approximately 380 nm to approximately 420 nm and at least one second light source that emits at a different peak wavelength, wherein a combined light output of the at least one first light source and the at least one second light source emits a colored light that is perceived as white light. The white light is defined by having a color rendering index (CRI) value of more than approximately 50. The at least one second light source that emits at a different peak wavelength consists of an xy coordinate on a International Commission on Illumination (CIE) 1931 xy color space diagram above a black body curve within a bounded area defined by a first line of approximately y=2.23989x−0.382773 and a second line of approximately y=1.1551x−0.195082. The combined light output has a proportion of spectral energy measured in the approximately 380 nm to approximately 420 nm range of greater than approximately 20%.
US09439987B2 Device and method for ultra-high temperature sterilization of an emulsion
A method for high temperature sterilization of an emulsion, in particular a dermocosmetic preparation. The method comprises the steps of gradually pre-heating, performing ultra-high temperature sterilization and gradually cooling the emulsion. The emulsion is heated up to a pre-heating temperature, which is the temperature of the emulsion at the stability limit. Ultra-high temperature sterilization is performed by infusion of the pre-heated emulsion by heating the emulsion up to a sterilization temperature, maintaining the emulsion at the sterilization temperature, and cooling the emulsion under a vacuum at an end-of-sterilization temperature. The emulsion is gradually cooled with agitation to a storage temperature.
US09439974B2 Conjugated biological molecules and their preparation
Novel biologically active compounds of the general formula (I) in which one of X and X′ represents a polymer, and the other represents a hydrogen atom; each Q independently represents a linking group; W represents an electron-withdrawing moiety or a moiety preparable by reduction of an electron-withdrawing moiety; or, if X′ represents a polymer, X-Q-W— together may represent an electron withdrawing group; and in addition, if X represents a polymer, X′ and electron withdrawing group W together with the interjacent atoms may form a ring; each of Z1 and Z2 independently represents a group derived from a biological molecule, each of which is linked to A and B via an amine group; or Z1 and Z2 together represent a single group derived from a biological molecule which is linked to A and B via two amine groups; A is a C1-5 alkylene or alkenylene chain; and B is a bond or a C1-4 alkylene or alkenylene chain; are formed by conjugating a suitable polymer to a suitable biologically active molecule via amine groups in said molecule, preferably via a disulphide bridge.
US09439968B2 Amine-containing lipidoids and uses thereof
Provided herein are lipidoids that may be prepared from the conjugate addition of alkylamines to acrylates. In some embodiments, provided lipidoids are biodegradable and may be used in a variety of drug delivery systems. Given the amino moiety of the lipidoids, they are well-suited for the delivery of polynucleotides, in addition to other agents. Nanoparticles containing the inventive lipidoids and polynucleotides have been prepared and have been shown to be effective in delivering siRNA.
US09439966B2 Multi-component nanochains
A multi-component nanochain for use in diagnostic and therapeutic applications includes at least three nanoparticles linked together to form the nanochain. At least one nanoparticle of the nanochain has an asymmetric surface chemistry defined by asymmetrically disposed first linkers and second linkers. The nanoparticles are linked to form the nanochain by linking first linkers and/or second linkers disposed on separate nanoparticles.
US09439965B2 Thermal treatment of the skin surface with metal nanoparticles in surfactant containing solutions
Treatment of skin tissue with photoactive materials and light, such as nanoparticles and formulations which are useful for cosmetic, diagnostic and therapeutic applications to mammals such as humans. In particular, embodiments of thermal treatment of the skin surface with metal nanoparticles in surfactant containing solutions are disclosed.
US09439964B2 Thermal treatment of the skin surface with coated metal nanoparticles
Treatment of skin tissue with photoactive materials and light, such as nanoparticles and formulations which are useful for cosmetic, diagnostic and therapeutic applications to mammals such as humans. In particular, embodiments of thermal treatment of the skin surface with coated metal nanoparticles are disclosed.
US09439959B2 Chimeric influenza virus-like particles
Chimeric Influenza virus-like particles including gag polypeptides are described. Virus-like particles are generated with a gag polypeptide, a neuraminidase polypeptide and optionally a hemagglutinin polypeptide. Preferred methods of generation include expression in insect cells.
US09439956B2 Application of mRNA for use as a therapeutic against tumour diseases
The present invention relates to a pharmaceutical composition comprising at least one mRNA comprising at least one coding region for at least one antigen from a tumor, in combination with an aqueous solvent and preferably a cytokine, e.g. GM-CSF, and a process for the preparation of the pharmaceutical composition. The pharmaceutical composition according to the invention is used in particular for therapy and/or prophylaxis against cancer.
US09439952B2 Rapid-acting insulin compositions
The invention is a composition of human insulin or insulin analog that includes treprostinil and that has faster pharmacokinetic action than commercial formulations of existing insulin analog products.
US09439948B2 Degradable cage coated with mineral layers for spinal interbody fusion
A cage for facilitating fusion of bones, such as vertebrae, or fusion of adjacent bone surfaces is disclosed. In one form, the cage includes a plurality of spaced apart walls comprising a biodegradable polymeric material (e.g., polycaprolactone); an osteoconductive mineral coating (e.g., a calcium compound) on at least a portion of the walls; and a bioactive agent (e.g., a bone morphogenetic protein) associated with the polymeric material and/or the coating. The bioactive agent is present in amount that induces ossification between the bones or adjacent bone surfaces. The cage may also include a fixation plate connected to at least one of the walls.
US09439945B2 Isolated nucleotide sequences encoding GDF traps
In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
US09439943B2 Use of melanocortins to treat insulin sensitivity
The present invention relates to peptide ligands of the melanocortin receptors, in particular the melancortin-4 receptor, and as such, are useful in the treatment of disorders responsive to the activation of this receptor, such as insulin resistance.
US09439939B2 Heavy metals defense
A dietary supplement comprising powdered ingredients: a) dehydrated seaweed: 40-60 wt. %, b) seawater extract: 20-40 wt. %, c) grape seed powder: 10-20 wt. %, d) Chlorella: 5-10 wt. %, e) Spirulina: 5-10 wt %, methods of making and using the composition.
US09439938B2 Use of avocado skin for obtaining an avocado unsaponifiable material enriched with saturated aliphatic hydrocarbons and with sterols
The present invention relates to the use of avocado peels in order to obtain avocado unsaponifiable enriched in saturated aliphatic hydrocarbons and in sterols, said avocado peels accounting for 5 to 50% by weight relative to the total weight of avocado used. The invention also relates to a method for obtaining avocado unsaponifiable enriched in saturated aliphatic hydrocarbons and in sterols from at least avocado peels, said avocado peels accounting for 5 to 50% by weight relative to the total weight of avocado used. The invention also relates to an avocado unsaponifiable enriched in saturated aliphatic hydrocarbons and in sterols, obtainable by this method. Lastly, the invention relates to an avocado unsaponifiable enriched in saturated aliphatic hydrocarbons and in sterols, for use as a drug, advantageously in the in the prevention and/or treatment of conjunctive tissue disorders such as arthrosis, articular pathologies such as rheumatism, or periodontal diseases such as gingivitis or periodontitis.
US09439929B2 Treatment of graft-versus-host disease
This present application describes a therapeutic agent for treating acute or chronic graft-versus-host disease using clonal marrow stem cells (cMSCs) as active ingredient.
US09439928B2 Method for combined conditioning and chemoselection in a single cycle
A method of radiation-free hematopoietic stem cell (HSC) transplantation comprises administering to a mammalian subject one or two doses of 2 to 10 mg/kg body weight of a purine base analog, such as 6TG as a pre-conditioning step. The method further comprises engrafting into the subject hypoxanthine-guanine phosphoribosyltransferase (HPRT)-deficient donor HSCs within 48 to 72 hours of the pre-conditioning step; and administering to the subject about 1 to 5 mg/kg of the purine base analog every two to four days for two to eight weeks following the engrafting step. The method is performed in the absence of pre-conditioning via radiation. The subject is therefore not treated with myeloablative radiation in preparation for transplantation, and thus the subject is free of myeloablative radiation-induced toxicity.
US09439926B2 Topical systems and methods for treating sexual dysfunction
The present invention generally relates to compositions and methods for topical or transdermal delivery, and treatment of sexual dysfunction. The compositions can be used in a variety of applications, including treating erectile dysfunction or sexual dysfunction. In some cases, the composition may include nitric oxide and/or peptides. The nitric oxide and/or peptide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other vesicles containing nitric oxide, peptides, or both. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin, e.g., onto the penis, vulva, or other suitable portion of the skin. The composition can also be applied to a mucosal surface in some instances. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like.
US09439924B2 Therapeutic miRNAs for treating heart and skeletal muscle diseases
The present disclosure describes the role for miR-322(424)/503 in the differentiation of cardiac precursor cells. Thus, the use of these molecules in the programming of resident stem/progenitor cells into cardiomyocytes, both in vitro and in vivo. Such methods find particular use in the treatment of patients post-myocardial infarction to prevent or limit scarring and to promote myocardial repair.
US09439922B2 Tat DNA sequences, gene constructs, vaccine and processes thereof
The present invention relates to non toxic, immunogenic viral Tat DNA sequences comprising wherein the Tat Sequence is rendered non toxic and immunogenic by insertion of T-Helper Epitope into the Cysteine-rich domain, or Basic domain or Core domain of said Tat DNA sequence, optionally along with insertion of a synthetic Intron between C-terminal region and Exon II region of the Tat DNA Sequence. The present invention also relates to elongation factor promoter constructs and process thereof. Also the present invention relates to a process of obtaining the non toxic and immunogenic Tat DNA sequence and vaccine and a method thereof.
US09439920B2 Composition for the management of nausea and vomiting
A pharmaceutical dosage system comprising (a) an effective amount of one or more of Doxylamine, an analog thereof, a derivative thereof, a prodrug thereof, a metabolite thereof and/or a salt thereof; (b) an effective amount of one or more of (i) Pyridoxine, (ii) an analog thereof, (iii) a derivative thereof, (iv) a prodrug thereof, (v) a metabolite thereof and (vi) a salt of any of (i)-(v); and (c) an effective amount of one or more compounds of formula (I) wherein R is H, PO3- or The system exhibits an improved pharmacokinetic profile relative to the current Diclectin®/Diclegis® formulation and is useful for example for the alleviation of the symptoms of nausea and vomiting, for example in the case of nausea and vomiting of pregnancy (NVP).
US09439913B1 Fat-soluble vitamin formulations
The present disclosure generally pertains to formulations containing two or more fat-soluble vitamins, lemon oil, and zinc. Also disclosed are kits containing such formulations and methods for administering such formulations to treat malabsorption in subjects diagnosed with CF, Crohn's Disease, Colitis, Irritable Bowel Syndrome, Celiac Disease, and other like conditions.
US09439909B2 Compositions and methods for sensitizing a neoplastic cell to radiation
The invention provides for the use of radiation sensitizing agents in combination with radiation for the treatment of neoplasia, methods for the identification of genotype-specific radiation sensitizing agents, and methods of identifying patients who could benefit from therapy with a genotype-specific radiation sensitizing agent.
US09439908B2 Cross-linking composition delivered by iontophoresis, useful for the treatment of keratoconus
An improved formulation of an ophthalmic composition contains riboflavin, as cross-linking agent of corneal collagen, administered by corneal iontophoresis, able to guarantee an increased capacity of permeation of riboflavin of the corneal stroma and therefore greater therapeutic efficacy in the treatment of keratoconus.
US09439900B2 Abuse-resistant pharmaceutical composition for the treatment of opioid dependence
There is provided pharmaceutical compositions for the treatment of e.g. opioid dependency comprising microparticles of a pharmacologically-effective amount of buprenorphine, or a pharmaceutically-acceptable salt thereof, in associative admixture with particles comprising a weak acid, or particles comprising weakly-acidic buffer forming materials. The composition may further comprise a disintegrant and/or particles of a pharmacologically-effective amount of naloxone, or a pharmaceutically-acceptable salt thereof. The compositions are useful in the treatment of opioid dependency/addiction and/or pain.
US09439898B2 Methods for novel drug discovery, treatment and selective targeting for gefitinib-resistant non-small-cell lung cancer harboring T790M mutation
The present invention relates to methods for novel drug discovery, treatment and selective targeting for Gefitinib-resistant non-small-cell lung cancer (NSCLC) harboring an additional mutation, in particular, to the discovery of a drug candidate or agent identified by the presently claimed method for use in treating and selective targeting Gefitinib-resistant NSCLC harboring T790M mutation.
US09439897B2 Use of psoralen derivatives and combination therapy for treatment of cell proliferation disorders
Methods for the treatment of a cell proliferation disease or disorder in a subject, involving applying a psoralen derivative lacking a DNA cross-linking motif to cancer cells, applying a psoralen or a derivative thereof and lapatinib, or applying a psoralen or derivative thereof and neratinib, to a subject and further applying initiation radiation energy form an energy source.
US09439886B2 Methods for producing crosslinked flavonoid hydrogels
There is provided methods for producing a hydrogel comprising conjugates of a hydrogel forming agent and a flavonoid including a method for producing a hydrogel that is capable of adhesion of cells and which comprises enzymatically cross-linked conjugates of a hydrogel forming agent and a flavonoid. There is also provided a method for producing a hydrogel comprising conjugates of a hydrogel forming agent and a flavonoid without the addition of an exogenous peroxide or peroxidase or without the addition of an exogenous peroxide. Hydrogels produced by such methods and methods of using the hydrogels are also described herein.
US09439882B2 Compounds and compositions for the treatment of cancer
New uses for phenylketone carboxylate compounds and substituted aromatic compounds of Formula I, Formula I.1, Formula I.2, Formula IA, Formula IB, Formula IC and Formula II and their pharmaceutical acceptable salts for the treatment of cancer. The use of a combination of two of these compounds is described and the use of the combination of one of these compounds with an anticancer agent such as decarbazine, doxorubicin, daunorubicin, cyclophosphamide, busulfex, busulfan, vinblastine, vincristine, bleomycin, etoposide, topotecan, irinotecan, taxotere, taxol, 5-fluorouracil, methotrexate, gemcitabine, cisplatin, carboplatin and chlorambucil.
US09439875B2 Anxiolytic effect of pterostilbene
We report for the first time that pterostilbene, a natural analog of resveratrol, shows anxiolytic-like action by downregulating phosphorylated levels of ERKs in the hippocampus of mice. Mice administered pterostilbene (1-10 mg/kg BW) by oral gavage were subjected to the Elevated-plus maze (EPM) test. Pterostilbene manifested anxiolytic activity at 1 and 2 mg/kg doses, demonstrated by an increase in percent permanence time and number of entries in open arms, critical determinants correlated with anxiety. This anxiolytic activity of pterostilbene was comparable to that of diazepam at 1 and 2 mg/kg in the EPM. The percent traveled distance and the percent permanence time in the enclosed arms were decreased with the 1 and 2 mg/kg doses. The 5 and 10 mg/kg doses did not show any anxiolytic effect. Locomotor activity was unaffected in all doses. Western blot analysis corroborated the observed behaviors in the EPM, revealing a decrease in both ERK1 and ERK2 phosphorylation in hippocampal homogenates from mice treated with 1 and 2 mg/kg doses; the 5 and 10 mg/kg doses showed no significant effect on the phosphorylation of ERKs. Pterostilbene was detected in serum and brain tissue following a single oral administration, demonstrating that the compound can cross the blood-brain barrier to reach the brain regions, including hippocampus, and thereby exert its anxiolytic effect. Resveratrol, the parent molecule of pterostilbene, did not have any anxiolytic effect.
US09439873B2 Application aid
The invention relates to a transdermal therapeutic system (10) comprising an active ingredient depot (11) that contains at least one active ingredient, comprising an application face which is designed for applying on a skin and which is adhesive on at least some parts of the surface, and comprising a protective film (14) which covers the application face and which comprises a first protective film part (14a) and a second protective film part (14b). The first protective film part (14a) differs from the second protective film part (14b) in terms of physical properties.
US09439869B2 Nanoshells on polymers
Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided.
US09439865B2 Coating film, and granules and tablets each utilizing same
A coating film comprising ethyl cellulose as a component A and an (ethyl acrylate)-(methyl methacrylate) copolymer or a plasticized vinyl acetate polymer as a component B, and having a tensile elongation of 150% or more and a tensile strength of 9 N or more.
US09439863B2 Pharmaceutical dosage form
This invention relates to pharmaceutical dosage forms, particularly to pH dependent pharmaceutical dosage forms with enhanced and/or prolonged distribution of a pharmaceutical compound at a target site. More specifically, this invention relates to a controlled release intravaginal pharmaceutical dosage form and, more particularly, to a pharmaceutical dosage form which comprises microspheres encapsulated and/or embedded within a bioerodible polymeric matrix, together the microspheres and the matrix are formed into a caplet and/or tablet.
US09439860B2 Fenofibrate formulation
Various fenofibrate dosage forms contain a plurality of beads or particles, where the beads or particles include a pharmaceutical composition comprising fenofibrate; from 0.3% to 10% by weight of the beads or particles of a surfactant; and from about 5% to about 15% by weight of the beads or particles of a water soluble or water dispersible cellulosic binder. The mass ratio of the drug to the binder in the dosage form is between about 3.5:1 and 4.5:1; and the dosage form produces a first Cmax in vivo that is between about 10% and about 50% higher than a comparative Cmax produced by a comparative dosage form. The comparative dosage form comprises the drug and the binder in a ratio of between about 5:1 and 15:1.
US09439859B2 Adjuvant incorporation in immunoanotherapeutics
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface and an immunostimulatory moiety. In some embodiments, the immunostimulatory moiety is adjuvant. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof.
US09439858B2 Temperature sensitive liposome including cationic lipid and use thereof
Provided are a liposome including a cationic lipid, a pharmaceutical composition for the delivery of anionic drugs, and a method for delivering anionic drugs to a target site.
US09439857B2 Foam containing benzoyl peroxide
The present invention relates to foamable compositions for treating acne comprising benzoyl peroxide; to a therapeutic kit comprising such compositions; and to a method of treating acne using such compositions.
US09439856B2 Method of preparing composition for delivering an anionic drug
Disclosed is an effective method of preparing a composition for delivering an anionic drug, the composition comprising an anionic drug as an active ingredient, a cationic lipid, and an amphiphilic block copolymer, wherein the anionic drug forms a complex with the cationic lipid, and the anionic drug/cationic lipid complex is entrapped in a micelle structure formed by the amphiphilic block copolymer.
US09439849B2 Composition for preventing or alleviating skin wrinkles containing honeybush extract or fermented honeybush as an active ingredient
Provided is a composition for preventing or alleviating skin wrinkles containing honeybush (Cyclopia intermedia) extract, a fraction thereof, or a fermented honeybush as an active ingredient. More particularly, the honeybush extract or fermented honeybush of the claimed subject matter can reduce the length and depth of skin wrinkles caused by UV irradiation and reduce the thickness of the epidermal layer, in addition to suppress collagen tissue breakdown reactions, indicating it is excellent in alleviating skin wrinkles, so that it can be effectively used as an active ingredient of a composition for preventing or alleviating skin wrinkles.
US09439847B2 Composition for preventing hair loss or enhancing hair growth comprising cyclophilin A
The present invention relates to a composition for preventing hair loss or enhancing hair growth which comprises a cyclophilin A (CypA) protein, a nucleic acid having a nucleotide sequence encoding the CypA protein, or a CypA protein expression recombinant vector. The composition of the present invention is administered into skin cells to inhibit the IL-1 expression of the skin cells, to modulate the activities of ERK and c-jun, and to increase the expression of NF-kB p65, thereby promoting the growth and development of hair follicles. Therefore, the composition of the present invention can be useful in preventing hair loss or enhancing hair growth.
US09439839B2 Cosmetic solution, method for producing cosmetic solution, and cosmetic method
Provided are a cosmetic solution and a method for producing the cosmetic solution, the cosmetic solution being easy to store and also easy to handle during use, and moreover having a high moisturizing function, without the use of a preservative. Hyaluronic acid/or a hyaluronic acid compound is dispersed in a polyvalent alcohol, also, an organic acid and/or organic acid salt different from the hyaluronic acid and/or hyaluronic acid compound is dispersed in a polyvalent alcohol such that it contains no water. The solution contains 0.01 to 2.0 wt % hyaluronic acid and/or hyaluronic acid compound 97 wt % or more polyvalent alcohol, is weakly acidic; i.e. 5≦pH<7 due to the organic acid and/or organic acid salt.
US09439837B2 Composition
The present invention relates to a photosensitive composition comprising synthetic nanocrystalline hydroxyapatite or a synthetic precursor thereof doped with a rare earth ion, the use of the composition in restorative or cosmetic dentistry, a process for preparing the composition and a method of generating an image of an exposed dentinal surface of a tooth.
US09439834B2 Medicine distributing system
A medicine distributing system includes a cassette placement portion for temporary placement of an individual distributing cassette including a large number of cells, a medicine container placement portion for temporary placement of a container for medicines, a medicine transporting device configured to put the medicines into the cells, and a distribution control device configured to acquire individual medicine distribution information to control an operation of the medicine transporting device. The medicine distributing system additionally includes a carrier placement portion for temporary placement of a medicine container carrier capable of housing medicine containers in a vertical column, and a medicine container transporting device configured to transport the medicine containers from the carrier placement portion to the medicine container placement portion.
US09439828B2 Foot compression system
Methods and systems for dynamic compression of venous tissue enable improved blood movement in the extremities. In accordance with an exemplary embodiment, a pressure pad provides a compressive force to the venous plexus region of the foot. The pressure pad is successively withdrawn and re-pressed against the foot. Improved blood circulation may reduce the occurrence of undesirable complications such as deep vein thrombosis, ulcers, and the like.
US09439827B2 Tissue compression device with pressure indicator
Tissue compression devices having pressure indicators and methods of using the same. The tissue compression devices provide feedback to a user with respect to the pressure being applied to selected tissue at a selected location such as a radial artery to assist the user in applying the desired amount of pressure to the tissue (such as the pressure needed to achieve hemostasis at an access site). The pressure indication may be provided by a ring indicator that moves between two configurations (e.g., a concave configuration and a convex configuration), a bellow chamber in a housing, a bladder located below a bladder window, etc.
US09439825B2 Walker docking station
A walker stabilizing platform including a movement restrictor assembly for assisting a user of a walker in transitioning from a sitting position to a standing position wherein the movement restrictor assembly automatically moves from a position of engagement with the walker to a position of disengagement with the walker, and further includes means for allowing the user of the walker to move the movement restrictor assembly from the disengaged position to the engaged position without assistance.
US09439824B1 Back stretching device
A device for promoting the extension of the sacrospinal muscles of a person resting on a horizontal surface includes stand having a horizontal cross bar fixed at opposing ends thereof with one each of a front pair legs and a rear pair of legs. Each front leg is pivotally fixed with the cross bar and configurable in both collapsed and extended configurations. At least one rigid post projects away from the cross bar, and at least one elastomeric band, when suspended from the at least one post, is capable of supporting the person around his sacrospinal muscles above the horizontal surface. The front and rear legs rest on the horizontal surface such that the cross bar is elevated above the horizontal surface sufficiently high enough to accommodate the person thereon in a supine position.
US09439823B2 Patient transfer device
A patient transfer device for transferring a patient resting on a sheet from a first resting device to a second resting device.
US09439822B1 Lifting assembly
A lifting assembly includes a pillow that may be positioned between a user and a support surface after the user has fallen onto the support surface. The pillow may support a weight ranging between approximately 250 pounds and 500 pounds. A valve is attached to the pillow and a pump is selectively attached to the valve. The pump selectively urges air into the pillow thereby facilitating the pump to inflate the pillow. The pillow lifts the user upwardly from the support surface as the pillow is inflated thereby facilitating the user to stand up. The pillow reaches a height ranging between approximately 18 inches and 25 inches with respect to the support surface when the pillow is inflated.
US09439816B2 Structured fibrous web
The present disclosure is directed to disposable absorbent articles comprising a structured fibrous web, the structured fibrous web comprising thermally stable, hydrophilic fibers that are thermally bonded together using heat producing a base substrate that is thermally stable. The base substrate is textured via mechanical treatment to increase its thickness and optionally modified via over bonding to improve its mechanical and fluid handling properties. The structured fibrous web provides optimal fluid wicking and fluid acquisition capabilities and is directed toward fluid management applications.
US09439814B2 Elastic absorbent sanitary article for absorbing bodily fluids
An absorbent hygiene product for acquiring fluids, having a flexurally yielding topsheet and a flexurally yielding backsheet, has, disposed between these sheets, an absorbent laminate, which in turn has two flexurally yielding outer plies, arranged adheringly between which are at least two diagonally intersecting, pre-tensioned plies of elastic filaments, a quantity of a superabsorbent polymer being incorporated in each of the discrete sections thus formed, and the topsheet-side outer ply of the laminate consists of a hydrophobic material, and the backsheet-side outer ply of the laminate consists of a hydrophilic material.
US09439809B2 Method of sterilization of wound dressings
Methods of sterilizing articles such as wound dressings, include the steps of providing an article that includes a polymer layer, applying an aqueous solution to the polymer layer and applying electron beam radiation to the article. The polymer layer includes a hydrophobic organic matrix that includes an elastomeric polymer and hydrophilic polymeric microparticles dispersed within the elastomeric polymer. Applying the aqueous solution to the polymer layer at least partially swells the hydrophilic microparticles of the polymer layer. In some articles the polymer layer includes an elastomeric polymer, hydrophilic polymeric microparticles dispersed within the elastomeric polymer, and hydrophilic polymer particles with greater than 10 micrometers average particle size dispersed within the hydrophobic organic matrix. These articles may be sterilized by applying either electron beam or gamma radiation.
US09439806B2 Foot pedal system and apparatus
A phacoemulsification system and method, and a foot pedal device, system and method. The devices, systems and methods may include a console comprising a plurality of modes for at least one physically associated surgical instrument, and a foot pedal communicatively associated with said console and suitable for varying ones of the plurality of modes. The foot pedal may include a foot pedal base, and at least two electronically actuated sensors physically associated with the foot pedal base, communicatively connected to the console, and suitable for receiving physical indications of variations in ones of the plurality of modes.
US09439805B2 Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
Methods, devices, and systems employ cryolysis of oropharyngeal adipose tissues to selectively remove fat cells from the tissues causing obstructive sleep apnea. In various embodiments, a chilled liquid—e.g., a liquid or air—is applied to the target tissue at a temperature and for a duration sufficient to cause cryolysis.
US09439799B2 Joint support device
A joint support device is provided. The joint support device may include a first tubular layer and a second tubular layer both made of crisscrossing fibers. The crisscrossing fibers of the first tubular layer may be oriented in a spiral in a first direction and the crisscrossing fibers of the second tubular layer may be oriented in a spiral in an opposite direction of the first direction. The first and second tubular layers may be layered together and may be attached to an existing elastic knee brace.
US09439798B2 Prefabricated walking boot
The present invention includes a walking boot device which immobilizes the ankle at about a 90° angle using a single anterior post that is angled at about 90° at an ankle joint from a lateral view, and encompasses an anterior one half of a calf proximally, and a dorsal one half of a forefoot distally. The post includes medial and lateral wings. The present invention defines an area for a medial and lateral malleolus and is narrow at the ankle and wider at the calf for a more anatomical fit. The present invention is secured to a leg using hook and loop fastener (Velcro®) strapping attached proximally around the calf posteriorly, away from any bony prominences. The hook and loop fastener (Velcro®) strapping is attached to the medial and lateral wings through brackets that are riveted into the wings. The present invention further includes foam inserts and a pneumatic bladder.
US09439795B2 Retainers for transcatheter heart valve delivery systems
A delivery device 10 for a collapsible prosthetic heart valve includes a catheter assembly 16 including a shaft 26 around which a compartment 23 is defined, the compartment 23 being adapted to receive the valve in an assembled condition, and a retainer 30 including a pusher 32 and a holder 34 adapted to retain a stent portion 106 of the valve. The catheter assembly 16 also includes a distal sheath 24 adapted to selectively cover and uncover the compartment 23 and the valve, the distal sheath 24 extending around the shaft 26 at least when the distal sheath 24 covers the compartment 23. The pusher 32 includes one or more recesses 40 in a retention edge 33 thereof, each recess 40 being adapted to receive a junction 107 at an end of the stent portion 106 of the valve. The holder 34 includes one or more elongated ribs 50, each rib 50 being adapted to fit into a cell opening 108 of the stent portion 106 of the valve.
US09439793B2 Extension for iliac branch delivery device and methods of using the same
Methods for accessing the common and internal iliac arteries and delivering and deploying an endovascular graft therein are disclosed. A system including a pre-loaded delivery and deployment device with an extension sheath is described which enables such a method to be practiced is also disclosed.
US09439792B2 Method of making implantable prosthesis with depot retention feature
A prosthesis for intraluminal drug delivery can comprise a plurality of interconnected struts that form a tubular scaffold structure. The struts include through-holes with an inner surface configured to retain a bioabsorbable depot. The bioabsorbable depot includes a drug-polymer composition that hydrolytically degrades upon implantation. The inner surface of the through-hole can be an entirely smooth and continuous area that is concave or convex, with no geometric discontinuities. The inner surface of the through-hole can include any number of constricted and distended regions to form grooves of a size and shape carefully selected to engage a corresponding geometric feature of the bioabsorbable depot.
US09439791B2 Stent and stent delivery device
In one embodiment according to the present invention, a stent is described having a generally cylindrical body formed from a single woven nitinol wire. The distal and proximal ends of the stent include a plurality of loops, some of which include marker members used for visualizing the position of the stent. In another embodiment, the previously described stent includes an inner flow diverting layer.
US09439790B2 Stent with anti-migration feature
An intraluminal prosthesis includes an outer three-dimensional (3D) anti-migration structure that is attached to the outer wall of a fully covered or partially covered stent to prevent migration and still allow stent removal at a later period of time. A method of manufacturing the intraluminal prosthesis includes attaching the anti-migration structure by usage of a polymer such as polyurethane.
US09439789B2 Implantable medical device having enhanced endothelial migration features and methods of making the same
An implantable medical device having enhanced endothelial migration features, generally comprises: a structural member including a leading edge and a trailing edge interconnected by a third surface region, the leading edge including a second surface region in a generally curvilinear cross-section, and the trailing edge including a fourth surface region in a generally curvilinear cross-section, whereby blood flow over the second surface region generate shear stress at the second surface region without an eddy region in the second surface region.
US09439787B2 Method of coating a stent
A method of coating a stent is provided that minimizes damage to the coating. The stent is self-expanding and made of a superelastic material. The stent is initially cooled so that at least part of the structure of the stent transforms to a martensitic phase. The stent is then compressed, coated and loaded while the structure of the stent remains at least partially martensitic. After the stent is loaded into a tubular restraint, the loaded stent is allowed to warm to room temperature.
US09439781B2 Patient-matched guides for orthopedic implants
Systems, devices, and methods are provided for implanting and aligning orthopedic implants. A patient-matched alignment guide is used to orient tools and implants intraoperatively. In certain embodiments, the systems, devices, and methods include an orthopedic guide comprising a body having a bottom surface, wherein at least a portion of the bottom surface has predetermined surface characteristics that correspond to respective characteristics of a patient's bony anatomy, and a pliable flange that extends from the bottom surface and is shaped to be received within an undercut of an implant to releasably couple the orthopedic guide to the implant.
US09439776B2 In-situ formed intervertebral fusion device and method
An orthopedic device for implanting between adjacent vertebrae comprising: an arcuate balloon and a hardenable material within said balloon.In some embodiments, the balloon has a footprint that substantially corresponds to a perimeter of a vertebral endplate. An inflatable device is inserted through a cannula into an intervertebral space and oriented so that, upon expansion, a natural angle between vertebrae will be at least partially restored. At least one component selected from the group consisting of a load-bearing component and an osteobiologic component is directed into the inflatable device through a fluid communication means.
US09439775B2 Artificial intervertebral disc with lower height
An intervertebral disc is provided having an upper plate, a lower plate, and a core. The upper and lower plates include outer vertebral body contacting surfaces which are provided with attachment enhancing features to ensure bone integration. The attachment enhancing features shown include one or more fins, serrations and teeth. An opposite surface of the plates from the vertebral body contacting surfaces is formed with a recess which serves as a bearing surface for the core. In order to form an intervertebral disc with a lower disc height, at least one of the recesses is provided opposite a corresponding dome shaped portion on the vertebral body contacting surfaces. This allows the plates to be formed with a thinner profile for a smaller overall disc height. In addition to providing a lower overall height to the artificial disc, the dome shaped portion of the plates also provides a more anatomically shaped outer vertebral body contacting surface.
US09439771B2 Laterally expandable spinal prosthesis
An expandable spinal prosthesis is disclosed, including a first surface having a first plurality of tissue anchors; a second surface opposite the first surface, the second surface having a second plurality of tissue anchors; a first wall between the first and second surfaces, and a second wall between the first and second surfaces, the second wall located opposite the first wall and being movable with respect to the first wall. A surgical instrument is also provided, including an elongated shaft defining a proximal end and a distal end; a first prosthesis engagement element accessible from the proximal end and extending from the distal end; and a second prosthesis engagement element accessible from the proximal end and extending from the distal end, the second prosthesis engagement element including a plurality of gear teeth.
US09439768B2 Glenoid vault fixation
A joint prosthesis system, specifically a shoulder prosthesis, for shoulder replacement, revision and repair. The implants provide fixation into the best bone available to a surgeon. The implants are used in a superior-inferior and anterior-posterior construct forming a type of cross or X-shape. The implants allow for interchangeability of the articulating component as well as rotational orientation. The systems will allow for augments to accommodate bone loss. The implants may allow for additional security using screws or anchors inserted into the scapula.
US09439767B2 Patient-adapted and improved articular implants, designs and related guide tools
Methods and devices are disclosed relating improved articular models, implant components, and related guide tools and procedures. In addition, methods and devices are disclosed relating articular models, implant components, and/or related guide tools and procedures that include one or more features derived from patient-data, for example, images of the patient's joint. The data can be used to create a model for analyzing a patient's joint and to devise and evaluate a course of corrective action. The data also can be used to create patient-adapted implant components and related tools and procedures.
US09439766B2 Multi-layered prosthetic constructs, kits, and methods
Multi-layered prosthetic constructs, kits, and methods are disclosed. A prosthetic construct can include a first ceramic component having a first surface, the first ceramic component comprising a first ceramic material, and a second ceramic component having a second surface disposed on the first surface of the first ceramic component, the second ceramic component comprising a second ceramic material. The second ceramic material of the second ceramic component can exert a compressive force on the first ceramic material. A ceramic material of the second ceramic component can include a different coefficient of thermal expansion than a ceramic material of the first ceramic component. Optionally, a ceramic construct can include a ceramic component and a membrane disposed onto and bonded to at least a portion of the ceramic component, the membrane configured to provide fracture reinforcement to the ceramic component.
US09439765B2 Method for subchondral treatment of joint pain using implantable devices
Implantable devices for the surgical treatment of bone, and particularly to a bone defect at a joint region, and even more particularly at the subchondral bone level of the joint region, are disclosed. The implantable devices may be formed of a bone material, and configured to serve the dual functions of providing mechanical strength and structural integrity to the area to be treated, while also facilitating the dispersal of a flowable material in the same area. Associated delivery tools are also provided.
US09439763B2 Prosthetic valve for replacing mitral valve
Embodiments of prosthetic valves for implantation within a native mitral valve are provided. One embodiment of a prosthetic valve includes a radially compressible main body and a one-way valve member. In some cases, the prosthetic valves also include ventricular anchors and/or an atrial portion coupled to and disposed outside of the main body. Methods, devices, and systems for delivering such prosthetic valves to the native mitral valve and implanting them therein are also provided.
US09439761B2 Stentless support structure
A stentless support structure capable of being at least partly assembled in situ. The support structure comprises a braided tube that is very flexible and, when elongated, becomes very long and very small in diameter, thereby being capable of placement within a small diameter catheter. The support structure is preferably constructed of one or more thin strands of a super-elastic or shape memory material such as Nitinol. When released from the catheter, the support structure folds itself into a longitudinally compact configuration. The support structure thus gains significant strength as the number of folds increase. This radial strength obviates the need for a support stent. The support structure may include attachment points for a prosthetic valve.
US09439758B2 Blood vessel prosthesis and delivery apparatus
A prosthesis for locating at a branch region of a blood vessel. The prosthesis comprises a main conduit (10) having a tubular portion (11) with first and second ends (12,13), and at least one projecting portion (14,15,16) projecting from the first end of the tubular portion. One or more branch conduits (17,18) are connected to, and extend from the projecting portions or the tubular portion at a position adjacent the projecting portions. Portions of the prosthesis to which the branch conduits are attached may be more flexible and/or elastic than other portions of the prosthesis.
US09439756B2 Device for inserting an intra-ocular lens
An IOL injector system includes an injector; a holder for holding an IOL; and a container for holding the holder. The injector has an injection channel and a plunger movable down the channel; and a holder receiving space for snappingly receiving the holder, and the holder has a channel part with a channel forming part of the injection channel of the injector when the holder is snapped into the receiving space of the injector in line with the injection channel, the IOL being provided in the channel of the holder when holding the IOL; and opposite openings for allowing the IOL to pass, allowing the plunger to urge the IOL out of the holder and through the injection channel. The container has a reservoir for holding a storage liquid and holder; closing walls for closing the opposite openings of the holder; and retaining parts for holding the holder.
US09439753B2 Graft anchor system and method
A graft anchor has first and second arms each having a leading end, a trailing end, an inner surface, and an outer bone contactable surface. The graft anchor also has a resilient bridge extending between the inner surface of the first arm and the inner surface of the second arm to space apart the first arm and the second arm. The resilient bridge defines a graft receiving pathway between the inner surfaces of the first and second arms. The resilient bridge also defines a deflection point about which a force acting upon the resilient bridge in a direction from the leading end to the trailing end causes the leading ends of the first and second arms to move toward one another and the trailing ends of the first and second arms to move away from one another.
US09439751B2 Hemostasis valve and delivery systems
A hemostasis valve includes a longitudinal valve housing, a gasket, a grip assembly and an interference element. A x-valve includes a valve housing, at least one sealing component and a support layer. Stent graft delivery systems include a handle, an internal lead screw assembly, a lead screw nut, a support member fixed to the handle body, a sheath and a hemostasis valve.
US09439749B2 Knit with zones without barbs, method of making same and prostheses obtained therefrom
The present invention relates to an openwork prosthetic knit (1) made from a single piece based on first yarns of biocompatible polymer materials that define a first face (2) and a second face that are opposite one another and on a second biocompatible yarn that generates barbs (3) that protrude outwards from at least said first face, characterized in that said first face comprises at least one zone in which it is provided with said barbs and at least one zone (5) in which it is free of such barbs. It also relates to a process for manufacturing such a knit (1) and to a prosthesis comprising such a knit (1).
US09439748B2 Pessary device
A pessary device having a top, a base, a length, a longitudinal axis, and a hollow interior. The pessary device has a hollow interior containing a protuberance.
US09439747B2 Adjustable medical assembly for implant tension adjustment
The present invention discloses a medical assembly and method to deliver and place a bodily implant inside a patient's body. The medical assembly includes an insertion tool such that a portion of the insertion tool defines a lumen. The medical assembly further includes a carrier configured to be coupled to the insertion tool and including a passageway. The medical assembly also includes a flexible elongate member configured to pass through the passageway of the carrier and the lumen. The elongate member is also configured to be coupled to the bodily implant such that a portion of the elongate member between the bodily implant and the carrier defines a length.
US09439743B2 Fluid delivery device
There is a concern that a mechanical switch could be switched OFF due to movement of a body in which the switch is embedded. If the switch is switched OFF after being embedded, it is difficult to switch the switch back ON. Provided is a fluid delivery device that is used by being embedded within a body, including a fluid delivery mechanism for discharging fluid from a reservoir that contains the fluid to outside of the reservoir; a sending and receiving section that sends and receives information relating to control of the fluid delivery mechanism to and from an external apparatus; a power supply section that supplies power to at least one of the fluid delivery device and the sending and receiving section; and a mechanical switch that is capable of changing a supply path of the power only from a cutoff state to a conductive state.
US09439739B2 Method of producing a dental restoration, dental restoration and use thereof
The invention relates to a method of producing a dental restoration (40), the method comprising the steps of providing a metallic frame (21) having an inner and an outer surface, applying one or more opaque layer(s) (23) or composition on the outer surface of the metallic frame, providing a facing precursor (31) having a volume A, mating the facing precursor on the outer surface of the metallic frame coated with the opaque layer using a mating composition to obtain a dental restoration intermediate, firing the dental restoration intermediate to a temperature where the facing precursor sinters to obtain a sintered facing having the volume B, and optionally applying a stain and/or glacing layer on the outer surface of the sintered facing. The invention also relates to a dental restoration obtainable by such a process.
US09439735B2 MRI-guided interventional systems that can track and generate dynamic visualizations of flexible intrabody devices in near real time
MRI guided cardiac interventional systems are configured to generate dynamic (interactive) visualizations of patient anatomy and medical devices during an MRI-guided procedure and may also include at least one user selectable 3-D volumetric (tissue characterization) map of target anatomy, e.g., a defined portion of the heart.
US09439733B2 Surgical robot system
A surgical robot system includes a slave device provided with a surgical instrument and a master device to control motion of the surgical instrument. The master device includes a master manipulation module having a manipulation tool, to which a pose recognizer is attached, and a master control module that estimates a pose of the manipulation tool using pose information acquired via the pose recognizer, generates a surgical instrument pose control signal corresponding to the estimated pose of the manipulation tool, and transmits the control signal to the slave device.
US09439731B2 Methods for reshaping cartilage structures
Described are methods and systems for reshaping a cartilage structure. Such methods comprise treating the cartilage structure with electromagnetic energy and fitting a device to the cartilage structure to retain it in the desired place, form, and/or orientation. Systems comprise an emitter of electromagnetic energy and a device to the cartilage structure to retain it in the desired place, form, and/or orientation.
US09439730B2 Dual-band dipole microwave ablation antenna
A triaxial microwave antenna assembly is disclosed. The triaxial microwave antenna includes a feedline having an inner conductor, a central conductor disposed about the inner conductor and an outer conductor disposed about the central conductor and a radiating portion including a high frequency radiating section and a low frequency radiating section.
US09439726B2 Methods for therapeutic renal neuromodulation
Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney.
US09439724B2 Resonating radio frequency ablation device
The invention relates to methods, systems, and devices for ablating a tumor with heat delivered from a non-ferrous metallic rod having a length adapted to support resonating radio frequency waves along the longitudinal axis of the rod. The tumor ablation may be carried out in an MRI where the radio frequency transmitter of the MRI wirelessly delivers the energy to heat the metallic rod.
US09439723B2 Variable stiffness catheter
A device and method for inserting a variable stiffness catheter into a subject with a catheter body being in relatively stiff state at a first temperature and a more flexible state at a second temperature. A temperature sensitive polymer is incorporated into the catheter that varies in stiffness depending on the temperature. The stiffness of the catheter is regulated by being in thermal contact with a circulating fluid within the catheter, or by being connected to resistive members in thermal contact with temperature sensitive alloys or polymers. The variable stiffness catheter can therefore be guided through the vasculature while in a relatively flexible state, but be changed into a relative stiff state during ablation procedures.
US09439715B2 Electrosurgical instrument
An electrosurgical instrument is provided for the treatment of tissue, the instrument comprising an instrument shaft (10) having a longitudinal axis, and an electrode assembly at one end of the shaft. The electrode assembly comprises first and second active electrodes (11), (14) and at least one return electrode (25), the electrodes being electrically insulated one from another by means of one or more insulation members (12). The first and second active electrodes (11, 14) each have an exposed surface for treating tissue, the exposed surface (19) of the first active electrode being such as to treat tissue disposed laterally of the longitudinal axis at a first radial position with respect to the instrument shaft. The exposed surface (15) of the second active electrode is such as to treat tissue disposed laterally of the longitudinal axis at a second radial position with respect to the instrument shaft. The instrument has a first set of connections by which the first active electrode (11) can be placed in circuit with the return electrode (25), and a second set of connections by which the second active electrode (14) can be placed in circuit with the return electrode (25).
US09439714B2 Vacuum coagulation probes
A surgical device integrating a suction mechanism with a coagulation mechanism is provided for improving lesion creation capabilities. The device comprises an elongate member having an insulative covering attached about means for coagulating soft tissue. Openings through the covering expose regions of the coagulation-causing elements and are coupled to lumens in the elongate member which are routed to a vacuum source. A fluid source to passively transport fluid along the contacted soft tissue surface may be provided in order to push the maximum temperature deeper into tissue.
US09439712B2 Heat-distribution indicators, thermal zone indicators, electrosurgical systems including same and methods of directing energy to tissue using same
An electrosurgical system includes an electrosurgical power generating source, an energy applicator operably associated with the electrosurgical power generating source, a heat-distribution indicator adapted to change echogenic properties in response to heat generated by energy delivered by the energy applicator, and a processor unit configured to generate at least one electrical signal for controlling at least one operating parameter associated with the electrosurgical power generating source. The system also includes an imaging system capable of acquiring image data. The imaging system is communicatively-coupled to the processor unit. The processor unit is adapted to determine an ablation rate at least in part based on analysis of one or more images acquired by the imaging system.
US09439707B2 Spray nozzle design for a catheter
A catheter-based medical device including controlled refrigerant dispersion is disclosed. The device includes a fluid injection tube that carries refrigerant from a coolant supply to the distal portion of the device. A fluid dispersion unit is disposed on the distal end of the fluid tube to control the angle of distribution for refrigerant that is expelled from the fluid injection tube. Controlling the angle of distribution for the refrigerant facilitates dispersion of the fluid in a predetermined spray pattern. The disclosure further relates to cryoablation treatment systems incorporating such a catheter, and to cryoablation treatment methods for tissue treatment to address various conditions suitably treatable with cryoablation.
US09439706B2 System and method for monitoring bioimpedance and respiration
A method of treating tissue is provided, including positioning a portion of a catheter in proximity to cardiac tissue; measuring an impedance value with the catheter; determining a respiratory rate based at least in part on the measured impedance value; and thermally treating the cardiac tissue with the catheter.
US09439704B2 Methods and devices for bone preparation
A manifold has at least one manifold aperture extending therethrough and selectively placed in fluid communication with a fluid source. An insertion structure has at least one interior cavity at least partially defined by a structure shell and is selectively placed in fluid communication with a corresponding manifold aperture. The insertion structure is configured for selective placement in a penetrating relationship with a patient tissue below a surface of the patient tissue. At least one shell perforation extends through the structure shell and places the interior cavity in fluid communication with a surrounding ambient space. At least one fluid path extends from the fluid source, through the manifold aperture, into the interior cavity, through at least one shell perforation, and at least one of a proximate relationship and a contacting relationship with the patient tissue beneath the outer surface thereof. A fluid is directed along the fluid path.
US09439697B2 Method of dynamically compressing a fracture
A system, devices and methods are provided for facilitating stabilization of periarticular fractures. The system includes a compression plate and one or more of a cerclage cable for encircling the bone and securing the compression plate to the bone, a crimp lug for securing the cable in tension relative to the bone and/or a plate, and a supplemental plate coupled to the compression plate and adapted to receive bicortical or unicortical bone screws to further secure the compression plate relative to the bone. In addition, the system includes a cable tensioner for temporarily retaining the cable in tension and then applying a tension to the cable until a desired compression is effected between a plate and bone and while a cable retaining structure is secured to the cable to retain the applied tension on the cable. Also provided is a jig for use with plates for minimally invasive fracture stabilization.
US09439694B2 Electrical intramedullary nail system
An intramedullary nail system including an elongated nail member comprising a cavity and electrically conductive at least in part, a coil assembly, a first electrode connected to a first pole of the coil assembly and a second electrode connected to a second pole of the coil assembly. To improve such an intramedullary nail system the coil assembly is provided in an end cap assembly that is proximally releasably connected to the nail member and with at least one electrically conductive outer contact surface. At least one section of the electrically conductive outer contact surface forms the first electrode and at least one section of the nail member forms the second electrode.
US09439693B2 Steerable needle assembly for use in vertebral body augmentation
Disclosed herein are devices for minimally invasive vertebral augmentation and restoration of spinal lordosis using a steerable cannula assembly. When deployed, the articulating cannula, including an outer cannula and an inner cannula extending into a central lumen of the outer cannula and coupled to each other at their distal ends, can be manipulated to curve/bend the body of the articulating cannula. This manipulation is used to create a void within the interior body and may also be used to control delivery of a treatment element to the interior body.
US09439692B1 Minimally invasive spinal fixation system and method therefor
A minimally invasive spinal fixation system comprises first and second bone screws each including a threaded shaft for respective engagement with a vertebra and a yoke articulatingly attached to the shaft, each yoke including a pair of upstanding opposed arms defining a slot therebetween. A connecting element has opposite ends and a longitudinal axis extending therebetween, the connecting element including a tab adjacent each end projecting from the connecting element transversely to the longitudinal axis. Bone screw extensions are provided for guiding the placement of the connecting element into the yoke slots, each extension having a pair of opposing slots that are sized to pass the tabs through the extensions when oriented in a first position and to prevent passage when the tabs are oriented in a second different position.