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US08969906B2 |
Active matrix electroluminescent device within resin sealed housing
In the present invention, a semiconductor film is formed through a sputtering method, and then, the semiconductor film is crystallized. After the crystallization, a patterning step is carried out to form an active layer with a desired shape. The present invention is also characterized by forming a semiconductor film through a sputtering method, subsequently forming an insulating film. Next, the semiconductor film is crystallized through the insulating film, so that a crystalline semiconductor film is formed. According this structure, it is possible to obtain a thin film transistor with a good electronic property and a high reliability in a safe processing environment. |
US08969905B2 |
Semiconductor light emitting device and method for manufacturing semiconductor light emitting device, and lamp
A semiconductor light-emitting device (1) of the present invention includes: a substrate (101); a laminated semiconductor layer (20) containing a light-emitting layer, which is formed on the substrate (101); a first electrode (111) formed on the upper surface (106c) of the laminated semiconductor layer (20); and a second electrode (108) formed on an exposed surface (104c) that is formed by partially cutting the laminated semiconductor layer (20), wherein the first electrode (111) includes a transparent electrode (109) containing a hole portion (109a) through which the upper surface (106c) of the laminated semiconductor layer (20) is exposed, a junction layer (110) formed on a bottom surface (109b) and an inner wall (109d) of the hole portion (109a), and a bonding pad electrode (120) formed to cover the junction layer (110). |
US08969904B2 |
Organic light emitting display device
An organic light emitting display device includes a first substrate, an organic light emitting diode array, a thin film encapsulation layer, a second substrate, a sealant member and a buffer layer. First substrate has a light emitting region and a non-light emitting region. OLED array is configured in light emitting region covered by encapsulation layer. Second substrate has a color filter array and is arranged opposite first substrate. Sealant member is disposed between first and second substrates. Buffer layer has a first light shielding layer disposed thereon, is arranged between first and second substrates, and is configured in light emitting region. Light shielding layer is arranged between buffer layer and encapsulation layer. The sum of the buffer layer's thickness and a gap distance from buffer layer to encapsulation layer has a range from 5 to 20 μm. Buffer layer has hardness smaller than that of the color filter array. |
US08969903B2 |
Optical element and semiconductor light emitting device using the optical element
An optical element includes a phosphor layer containing a phosphor which is excited by light of a first wavelength and radiates light of a second wavelength different from the first wavelength, a first optical member provided on a first surface of the phosphor layer and configured to concentrate light in the phosphor layer, and a second optical member provided on the first surface of the phosphor layer or the same side to which the first surface faces, or on a second surface opposite to the first surface, and configured to convert light radiated from the phosphor layer into parallel light. |
US08969899B2 |
Method for forming a light conversion material
A method and system for manufacturing a light conversion structure for a light emitting diode (LED) is disclosed. The method includes forming a transparent, thermally insulating cover over an LED chip. The method also includes dispensing a conversion material onto the cover to form a conversion coating on the cover, and encapsulating the LED, the silicone cover, and the conversion coating within an encapsulant. Additional covers and conversion coatings can be added. |
US08969895B2 |
Semiconductor light emitting device and manufacturing method thereof
A semiconductor light emitting device includes: a light emission structure in which a first conductive semiconductor layer, an active layer and a second conductive semiconductor layer are sequentially stacked; a first electrode formed on the first conductive semiconductor layer; an insulating layer formed on the second conductive semiconductor layer and made of a transparent material; a reflection unit formed on the insulating layer and reflecting light emitted from the active layer; a second electrode formed on the reflection unit; and a transparent electrode formed on the second conductive semiconductor layer, the transparent electrode being in contact with the insulating layer and the second electrode. |
US08969893B2 |
Light emitting device, light emitting device package, and lighting system
Provided are a light emitting device, a light emitting device package, and a lighting system. The light emitting device includes a light emitting structure, a non-periodic light extraction pattern, and a phosphor layer. The light emitting structure includes a first conductive type semiconductor layer, a second conductive type semiconductor layer over the first conductive type semiconductor layer, and an active layer between the first conductive type semiconductor layer and the second conductive type semiconductor layer. The non-periodic light extraction pattern is disposed over the light emitting structure. The phosphor layer is disposed over the non-periodic light extraction pattern. The phosphor layer fills at least one portion of the non-periodic light extraction pattern. |
US08969890B2 |
Solid state light emitting devices based on crystallographically relaxed structures
The present invention discloses a method for manufacturing a solid state light emitting device having a plurality of light-sources, the method comprising the steps of: providing a substrate having a growth surface; providing a mask layer on the growth surface, the mask layer having a plurality of openings through which the growth surface is exposed, wherein a largest lateral dimension of each of said openings is less than 0.3 μm and wherein the mask layer may comprise a first mask layer portion and a second mask layer portion, having the same surface area and comprising a plurality of openings wherein the first mask layer portion exhibits a first ratio between an exposed area of the growth surface and an unexposed area of the growth surface, and wherein the second mask layer portion exhibits a second ratio between an exposed area of the growth surface and an unexposed area of said growth surface, the second ratio being different from the first ratio; growing a base structure on the growth surface in each of the openings of the mask layer; and growing at least one light-generating quantum well layer on the surface of each of the base structures. |
US08969888B1 |
Flat panel display apparatus and method of manufacturing the same
A flat panel display apparatus including a substrate on which a display unit is formed, an encapsulation member that covers the display unit, a sealant that is formed between the substrate and encapsulation member while the sealant encapsulates the display unit by surrounding the display unit, and a metal layer that is formed on the substrate and located along with the sealant, the metal layer having irregular widths. |
US08969887B2 |
Light emitting device
A light emitting device includes: a support substrate; at least one light emitting laminate having a structure in which semiconductor layers are laminated and formed on the support substrate; a wall unit formed on the support substrate and surrounding the at least one light emitting laminate; and a wavelength conversion layer disposed above the at least one light emitting laminate. |
US08969882B1 |
Transistor having an ohmic contact by screen layer and method of making the same
A transistor includes a substrate, a channel layer over the substrate and an active layer over the channel layer. The active layer includes a first portion and a screen layer over the first portion. The transistor includes a metal layer over the screen layer. |
US08969881B2 |
Power transistor having segmented gate
There are disclosed herein various implementations of a transistor having a segmented gate region. Such a transistor may include at least one segmentation dielectric segment and two or more gate dielectric segments. The segmentation dielectric segment or segments are thicker than the gate dielectric segments, and is/are situated between the gate dielectric segments. The segmentation dielectric segment or segments cause an increase in the effective gate length so as to improve resistance to punch-through breakdown between a drain electrode and a source electrode of the transistor when the transistor is off. |
US08969877B2 |
Semiconductor device
A semiconductor device includes a semiconductor layer made of first conductivity type SiC; a second conductivity type well region formed on the semiconductor layer and having a channel region; a first conductivity type source region formed on the well region and including a first region adjacent to the well region and a second region adjacent to the first region; a gate insulating film formed on the semiconductor layer and having a first portion that contacts the first region; a second portion that contacts the well region and that has a thickness that is the same as that of the first portion; and a third portion that contacts the second region and that has a thickness that is greater than that of the first portion; and a gate electrode formed on the gate insulating film and opposed to the channel region where a channel is formed through the gate insulating film. |
US08969876B2 |
Array substrate for liquid crystal display device and method of fabricating the same
An array substrate includes first and second lines on a substrate and formed of a metallic material; a gate electrode connected to the first line; a gate insulating layer on the first and second lines and the gate electrode and including a groove exposing the substrate and positioned between the first and second lines; a semiconductor layer on the gate insulating layer and corresponding to the gate electrode; a data line crossing the first and second lines and on the gate insulating layer; a source electrode connected to the data line; a drain electrode spaced apart from the source electrode; a passivation layer on the data line, the source electrode and the drain electrode and including an opening, the opening exposing the gate insulating layer and the drain electrode; and a pixel electrode positioned on the gate insulating layer and in the opening and contacting the drain electrode. |
US08969873B2 |
Electrophoretic display and pixel structure therein
A pixel structure is formed in a pixel area and coupled to a scan line and a data line. The pixel structure includes a first transistor, a second transistor and a pixel electrode. The first transistor is formed in the pixel area and coupled to the scan line and the data line. The second transistor is formed in the pixel area and coupled to the first transistor. The pixel electrode is formed in the pixel area and coupled to the second transistor. The pixel electrode includes a main portion and a first branch portion. The first branch portion is disposed between the first transistor and the second transistor. An electrophoretic display including the pixel structure is also disclosed herein. |
US08969867B2 |
Semiconductor device
The semiconductor device includes a transistor including an oxide semiconductor film having a channel formation region, a gate insulating film, and a gate electrode layer. In the transistor, the channel length is small (5 nm or more and less than 60 nm, preferably 10 nm or more and 40 nm or less), and the thickness of the gate insulating film is large (equivalent oxide thickness which is obtained by converting into a thickness of silicon oxide containing nitrogen is 5 nm or more and 50 nm or less, preferably 10 nm or more and 40 nm or less). Alternatively, the channel length is small (5 nm or more and less than 60 nm, preferably 10 nm or more and 40 nm or less), and the resistivity of the source region and the drain region is 1.9×10−5 Ω·m or more and 4.8×10−3 Ω·m or less. |
US08969864B2 |
Organic light emitting device having a bulk layer comprising a first and second material
Disclosed is an organic light emitting diode device including an anode, a cathode, an emission layer between the anode and the cathode, and a buffer layer positioned between the emission layer and the anode. The buffer layer includes an oxide, fluoride, quinolate, or acetoacetate compound of an alkaline metal or an alkaline-earth metal, as well as a material having a work function of about 2.6 to about 4.5 eV. The buffer layer also has a thickness of about 30 Å to about 400 Å. |
US08969859B2 |
Display device and semiconductor device
An object is to provide a display device with a high aperture ratio or a semiconductor device in which the area of an element is large. A channel formation region of a TFT with a multi-gate structure is provided under a wiring that is provided between adjacent pixel electrodes (or electrodes of an element). In addition, a channel width direction of each of a plurality of channel formation regions is parallel to a longitudinal direction of the pixel electrode. In addition, when a channel width is longer than a channel length, the area of the channel formation region can be increased. |
US08969857B2 |
Luminance-enhancing polarising plate for an organic light-emitting element
There is provided a polarizer for organic light emitting diodes (OLED) having improved brightness. The polarizer, which comprises a linear polarizer and a ¼ retardation plate, comprises a reflective polarizer film disposed between the linear polarizer and the ¼ retardation plate and transmitting a polarized light horizontal to the transmission axis of the linear polarizer while reflecting a polarized light vertical to the transmission axis of the linear polarizer. The polarizer may be useful to highly improve the brightness of the OLED device when the polarizer is used in the OLED device. |
US08969856B2 |
OLED devices with internal outcoupling
Optoelectronic devices that have enhanced internal outcoupling are disclosed. The devices include a substrate, an anode, a cathode, an electroluminescent layer, and a hole injecting layer. The hole injecting layer includes inorganic nanoparticles that have a bimodal particle size distribution and which are dispersed in an organic matrix. |
US08969851B2 |
Detection device, photodiode array, and method for manufacturing the same
The present invention provides an image pickup device used to capture an image of an object by receiving light in a near infrared region reflected from the object. The image pickup device includes semiconductor light-receiving elements each having a light-receiving layer with a band gap wavelength of 1.65 to 3.0 μm. |
US08969850B2 |
Nano-structure arrays for EMR imaging
An electro-magnetic radiation detector is described. The electro-magnetic radiation detector includes a detector material and a voltage biasing element. The detector material includes a substantially regular array of nano-particles embedded in a matrix material. The voltage biasing element is configured to apply a bias voltage to the matrix material such that electrical current is directly generated based on a cooperative plasmon effect in the detector material when electro-magnetic radiation in a predetermined wavelength range is incident upon the detector material, where the dominant mechanism for decay in the cooperative plasmon effect is non-radiative. |
US08969849B2 |
Nitride semiconductor light emitting device and fabrication method thereof
Provided is a nitride semiconductor light emitting device including: a first nitride semiconductor layer; an active layer formed above the first nitride semiconductor layer; and a delta doped second nitride semiconductor layer formed above the active layer. According to the present invention, the optical power of the nitride semiconductor light emitting device is enhanced, optical power down phenomenon is improved and reliability against ESD (electro static discharge) is enhanced. |
US08969845B2 |
Memory cells having storage elements that share material layers with steering elements and methods of forming the same
A memory cell is provided that includes a steering element, a metal-insulator-metal stack coupled in series with the steering element, and a conductor above the metal-insulator-metal stack. The steering element includes a diode having an n-region and a p-region. The metal-insulator-metal stack includes a reversible resistivity-switching material between a top electrode and a bottom electrode, and the top electrode includes a highly doped semiconductor material. The memory cell does not include a metal layer disposed between the metal-insulator-metal stack and the conductor. The bottom electrode includes the n-region or the p-region of the diode, and the reversible resistivity-switching material is directly adjacent the n-region or the p-region of the diode. Numerous other aspects are provided. |
US08969840B2 |
Droplet generator with actuator induced nozzle cleaning
Systems (and methods therefor) for generating EUV radiation that comprise an arrangement producing a laser beam directed to an irradiation region and a droplet source. The droplet source includes a fluid exiting an orifice and a sub-system having an electro-actuatable element producing a disturbance in the fluid. The electro-actuatable element is driven by a first waveform to produce droplets for irradiation to generate the EUV radiation, the droplets produced by the first waveform having differing initial velocities causing at least some adjacent droplets to coalesce as the droplets travel to the irradiation region, and a second waveform, different from the first waveform, to dislodge contaminants from the orifice. |
US08969835B2 |
Particle beam system including a supply of process gas to a processing location
A system for supplying a process gas to a processing location of a particle beam system is disclosed. The system for supplying the processing gas includes a gas reservoir, a gas conduit, a pipe located close to the processing location, a valve between the gas conduit and the pipe, and a controller configured to open and to close the valve to switch the system from a first mode of operation in which process gas is not supplied to the processing location to a second mode of operation in which process gas is supplied to the processing location. The controller can alternately open and close the valve in cycles. Each cycle can include a first duration in which the valve is open and a second duration in which the valve is closed. The ratio of the first duration to the second duration can be changed. |
US08969834B2 |
Charged particle therapy patient constraint apparatus and method of use thereof
The invention comprises a rapid patient positioning system including a computer and motor controlled patient constraint system, such as a patient head and/or back support system having multiple adjustable degrees of freedom that facilitates accurate, precise, and rapid alignment of a patient relative to a support or table. The patient support system is preferably integrated with a rapid patient positioning system including steps of: positioning a patient relative to the table in a substantially vertical orientation, transitioning the table through a semi-vertical orientation, such as with a robot arm, and orientating the patient and the table in a substantially horizontal orientation, such as in a position for charged particle tumor therapy. Preferably, the robot arm is in common with an arm used to move the patient in traditional proton therapy. |
US08969833B1 |
Method and system for perceiving a boundary between a first region and a second region of a superabrasive volume
Methods of evaluating a superabrasive volume or a superabrasive compact are disclosed. One method may comprise exposing a superabrasive volume to radiation and detecting a response of the radiation when it interacts with the superabrasive volume. In one embodiment, a boundary may be perceived between a first region and a second region of the superabrasive volume in response to detecting the response of the radiation. In one particular embodiment, a boundary between a catalyst-containing region and a catalyst-diminished region of a polycrystalline diamond volume may be perceived. Additionally, a depth to which a catalyst-diminished region extends within a polycrystalline diamond volume of a polycrystalline diamond compact may be measured based on the monitored response of the radiation. In a further embodiment, a non-planar boundary between the two regions may be mapped. A system configured to evaluate a superabrasive volume is also disclosed. |
US08969830B2 |
Ophthalmic lens disinfecting base unit with programmable and communication elements
The present invention provides for a programmable processor in a disinfecting radiation base unit for working in conjunction with a storage case for an ophthalmic lens. The processor is operative via executable software to provide disinfecting radiation base radiation for disinfecting an ophthalmic lens. A disinfecting radiation base unit and storage case may also include sensors for providing data and a digital storage for storing the data. |
US08969829B2 |
Method and apparatus for aligning a multi-modality imaging system
A target object for aligning a multi-modality imaging system includes a body having a cavity therein, a first imaging source being disposed within the cavity, the first imaging source including a body having a cavity defined therein and an emission responsive material disposed within the first imaging source cavity, the first imaging source having a first shape, and a second imaging source being disposed within the cavity, the second imaging source including a body having a cavity defined therein and a magnetic resonance responsive material disposed within the second imaging source cavity, the second imaging source having a second shape that is different than the first shape. A method of aligning a multi-modality imaging system is also provided. |
US08969828B2 |
Scanning electron microscope with a table being guided by rolling friction elements
This invention stabilizes positioning and provides improved positioning accuracy in a scanning electron microscope provided with stage-driving means utilizing an effect of rolling friction.In this scanning electron microscope that includes a sample stage equipped with an x-table, a y-table, a z-table, a rotation table, and a tilting table, and moved by means of stepping motors each connected to a ball screw via a coupling, a sliding friction element is disposed at a position close to the ball screw, between the x-table and the y-table and between a tilting base and the x-table. |
US08969826B2 |
Flowthrough labyrinth device for use in detection of radiation in fluids and method of using same
The present invention provides a continuous flowthrough labyrinth device that has a detector well formed therein in which a radiation detection device may be placed. The continuous flowthough labyrinth device allows a fluid sample to be introduced into the flow path of the device so that the fluid sample evenly surrounds the top and side surfaces of the detector well, which results in the fluid sample being evenly distributed around the radiation detection device. The continuous flowthrough labyrinth device may be connected to any radiation level fluid monitoring system, for example systems used by municipalities and/or industries. The continuous flowthrough labyrinth device may be placed such that fluids entering and/or exiting systems are monitored for radiation, or even placed to determine the radiation levels of fluids within systems. |
US08969824B2 |
CsLiLn Halide scintillator
Li-containing scintillator compositions, as well as related structures and methods are described. Radiation detection systems and methods are described which include a Cs2LiLn Halide scintillator composition. |
US08969822B2 |
Two-dimensional and three-dimensional position sensing systems and sensors therefor
Two and three dimensional position sensing systems and sensors for use in such systems are disclosed. The sensors incorporate linear array sensors and an aperture plate to block light or other radiation from reaching most elements of the sensors. A direction of a radiation source relative is determined based on illuminated sensor elements in each sensor. The sensors are combined in systems to allow the position of a radiation source to be estimated. |
US08969821B2 |
Apparatus for detecting X-ray
An apparatus for detecting an X-ray includes a photo diode having an anode electrode and a cathode electrode, a switching transistor, and a first storage capacitor that has one end connected to the cathode electrode and another end connected to the switching transistor. |
US08969814B2 |
System and method of determining timing triggers for detecting gamma events for nuclear imaging
Systems and methods of generating timing triggers to determine timing resolutions of gamma events for nuclear imaging includes receiving a pulse signature representing a succession of triggers associated with a photomultiplier. When a number of triggers occurring within a predetermined time interval matches a predetermined number, an event trigger can be initiated. A delayed version of the pulse signature can be generated and compared to a predetermined timing trigger level. When the delayed version matches the predetermined timing trigger level, a timing trigger can be generated. Based on the timing trigger level, the timing trigger can be generated at the pulse of the delayed version that corresponds to the first photoelectron of a gamma event. The timing trigger can correspond to a timestamp for the first photoelectron so that a data acquisition system can identify the pulse from which to acquire energy information to generate a nuclear image. |
US08969811B2 |
Device to detect thermal radiation with high resolution method to manufacture and use the device
A device to detect thermal radiation has a membrane and at least two detector elements that are respectively set up to transduce thermal radiation into an electrical signal and are mounted situated next to one another on the membrane, wherein at least one heat dissipation path is provided on the side of the membrane facing towards the detector elements and/or on the side of the membrane facing away from the detector elements, which heat dissipation path has a higher heat conductivity than the membrane and is connected with the detector elements in a heat-conductive manner via the membrane so that heat can be discharged from the detector elements with the heat dissipation path, whereby the response time of the detector elements is short; and wherein at least one heat barrier that has a lower heat conductivity than the membrane and extends between the detector elements is provided integrated into the membrane, such that a heat conduction in the membrane from the one detector element to the other detector element is prevented by the heat barrier; whereby the crosstalk of the detector elements is low. |
US08969809B2 |
Thermo-optical array devices and methods of processing thermo-optical array devices
Thermo-optical array devices and methods of processing thermo-optical array devices are disclosed. One method of processing thermo-optical array devices includes forming an (001) oriented titanium dioxide material on a bolometer material, and forming a vanadium dioxide material on the (001) oriented titanium dioxide material. One thermo-optical array device includes a bolometer material, a titanium dioxide material on the bolometer material, and a vanadium dioxide material on the titanium dioxide material, wherein the vanadium dioxide material has an optical transition temperature of less than 67 degrees Celsius. |
US08969807B2 |
Carrier and adhesion amount measuring apparatus, and measuring method, program, and recording medium of the same
A carrier includes attachment holes to which a catalyst attaches, and non-attachment holes to which the catalyst does not attach. An attachment quantity measurement device includes an electromagnetic wave output device that outputs a terahertz wave toward the carrier, an electromagnetic wave detector that detects the terahertz wave which has transmitted through the carrier, a reference value obtainer that obtains, based on a result detected by the electromagnetic wave detector, any one of an absorption rate, a group delay, and a dispersion of the terahertz wave in the non-attachment holes, and an attachment quantity obtainer that obtains, based on the result detected by the electromagnetic wave detector and the result obtained by the reference value obtainer, a weight or a density of the catalyst present in the attachment holes. |
US08969797B2 |
MS/MS type mass spectrometer
The length of a delay time d from a suspension period starting point t1 until the application of a pulse voltage is begun is changed according to the length of the suspension period during which no data is collected at the time of m/z switching. It is thus ensured that the amount of product ions can be reliably restored at a suspension period termination point t2. In addition, the peak value of the pulse voltage is also changed according to the ionic strength immediately before entering the suspension period. The ion removal rate is thus increased when the amount of remaining ions is high, and the amount of remaining ions is reliably brought to zero within the same pulse width. As a result, crosstalk can be completely removed. |
US08969794B2 |
Mass dependent automatic gain control for mass spectrometer
Systems and methods for automatic gain control in mass spectrometers are disclosed. An exemplary system may include a mass spectrometer, comprising a lens configured to receive a supply of ions, and a mass analyzer. The mass analyzer may include an ion trap for trapping the supplied ions. The mass analyzer may also include an ion detector for detecting ions that exit the ion trap. The lens may focus the ions non-uniformly based on mass of the ions to compensate for space charge effects reflected in a measurement output of the mass spectrometer. An exemplary method may include focusing an ion beam into a mass analyzer. The method may also include obtaining a mass spectrum and identifying a space charge characteristic based on the mass spectrum. The method may further include defocusing the lens based on the identified space charge characteristic, wherein defocusing the lens is configured to divert lighter ions away from the entrance aperture. The method may include obtaining a mass spectrum of a defocused ion beam generated from the sample. |
US08969793B2 |
Downhole neutron activation measurement
Systems and methods for measuring neutron-induced activation gamma-rays in a subterranean formation are provided. In one example, a downhole tool for measuring neutron-induced activation gamma-rays may include a neutron source and a gamma-ray detector. The neutron source may emit neutrons according to a pulsing scheme that includes a delay between two pulses. The delay may be sufficient to allow substantially all neutron capture events due to the emitted neutrons to cease. The gamma-ray detector may be configured to detect activation gamma-rays produced when elements activated by the emitted neutrons decay to a non-radioactive state. |
US08969792B2 |
Apparatus and methods for measuring formation characteristics
An apparatus can measure characteristics of a formation surrounding a borehole. The apparatus includes a tool body having a neutron measurement section and a density measurement section. The neutron measurement section includes a neutron source and a neutron detector arrangement spaced in an axial direction from the neutron source. The density measurement section includes a gamma ray source and a gamma ray detector arrangement spaced in an axial direction from the gamma ray source. The neutron measurement section and the density measurement section are positioned in the tool body so that the sections overlap in the axial direction and are azimuthally spaced apart in the tool body. The tool body also includes shielding to block a direct signal path from the neutron source to the gamma ray detector arrangement and to block a direct signal path from the gamma ray source to the neutron detector arrangement. |
US08969789B2 |
Rotary encoder and method of detecting abnormality of rotary encoder
A signal output unit generates an A phase output signal of a rectangular wave and a B phase output signal of a rectangular wave from the A phase sinusoidal wave signal and the B phase sinusoidal wave signal, respectively and outputs the generated signals. An internal signal generating unit (comparator) generates an A phase internal signal of a rectangular wave and a B phase internal signal of a rectangular wave from the A phase sinusoidal wave signal and the B phase sinusoidal wave signal, respectively, which are further processed by counters, and an abnormality detector. Each counter resets in response to a pulse edge of a signal for detection. The abnormality detector detects an abnormality when the count value of at least one of counters reaches a prescribed value. |
US08969787B2 |
Optical detecting apparatus for computing location information of an object according to the generated object image data with a side light source for minimizing height
An optical detecting apparatus, which comprises: a detecting surface; a first light source, for providing light parallel to the detecting surface; an image sensor, for detecting an object close to the detecting surface, to generate object image data; and an object location determining apparatus, for computing location information of the object according to the object image. |
US08969785B2 |
Easily assembled optical-electrical converting device having engaged locating elements for an optical coupling lens
An optical-electrical converting device includes a printed circuit board (PCB), a light emitting module, a light receiving module, an optical coupling lens, and a locating frame positioned on the PCB. The PCB has two first locating elements. The optical coupling lens includes a first converging lens and a second converging lens. The locating element has two second locating elements. The two first locating elements and the two second locating elements cooperate to position the locating frame on the PCB. The locating element further has two third locating elements. The optical coupling lens has two fourth locating elements. The two third locating elements and the two fourth locating elements cooperate to position the coupling lens on the locating frame, and thus the first converging lens is aligned with the light emitting module, and the second converging lens is aligned with the light receiving module. |
US08969783B2 |
Optical receiver having positive feedback loop from photocurrent to bias for photodiode
An optical receiver is disclosed, in which a PD is biased by a positive feedback loop with respect to the photocurrent generated thereby. The optical receiver includes the PD, a current mirror to reflect the photocurrent into a mirror current, a current detector to convert the mirror current into a voltage signal, and a bias source stabilized by the negative feedback loop by sensing the output voltage thereof superposed with the voltage signal output by the current detector. The PD, the current mirror, the current detector and the bias source comprises the positive feedback loop for the photocurrent. |
US08969779B2 |
Photodetecting structure with photon sensing graphene layer(s) and vertically integrated graphene field effect transistor
In accordance with an example embodiment of the present invention, an apparatus is provided, including a photodetecting structure with one or more photon sensing layers of graphene; and an integrated graphene field effect transistor configured to function as a pre-amplifier for the photodetecting structure, where the graphene field effect transistor is vertically integrated to the photodetecting structure. |
US08969777B2 |
Method for processing images using object signals to estimate transfer functions of optical fibers
A method for processing images acquired by image detectors with non-uniform transfer functions and irregular spatial locations includes the steps of accumulating data from multiple images, defining an affinity graph which edges define pairs of detectors that measure related signal, performing statistical analysis on the accumulated data with respect to each pair of detectors, and solving a system of equations constructed from the results of the statistical analysis to estimate each detector transfer function, a set of solutions to the system of equations comprising a calibration of an imaging system. |
US08969776B2 |
Solid-state imaging device, method of manufacturing the same, and electronic apparatus having an on-chip micro lens with rectangular shaped convex portions
A solid-state imaging device includes a light sensing portion which is formed on a substrate and generates a signal electric charge according to incident light; a rectangular or gradient-index on-chip micro lens formed on a light incident side above the light sensing portion; and a planarized lens layer which covers the on-chip micro lens and is formed in such a manner that a light incident surface is planarized. |
US08969775B2 |
High dynamic range pixel having a plurality of amplifier transistors
A pixel cell for use in a high dynamic range image sensor includes a photodiode disposed in semiconductor material to accumulate charge in response to light incident upon the photodiode. A transfer transistor is disposed in the semiconductor material and is coupled between a floating diffusion and the photodiode. A first amplifier transistor is disposed in the semiconductor material having a gate terminal coupled to the floating diffusion and a source terminal coupled to generate a first output signal of the pixel cell. A second amplifier transistor is disposed in the semiconductor material having a gate terminal coupled to the floating diffusion and a source terminal coupled to generate a second output signal of the pixel cell. |
US08969774B2 |
Conversion circuitry for reducing pixel array readout time
An image sensor includes a pixel array having pixels arranged in rows and columns, a first successive-approximation-register (“SAR”) analog-to-digital-converter (“ADC”), a second SAR ADC, and first and second control circuitry. The first SAR ADC includes a first capacitor array (“FCA”) that shares a first common terminal coupled to a first comparator and coupled to receive first analog pixel signals. The second SAR ADC includes a second capacitor array (“SCA”) that shares a second common terminal selectably coupled to a second comparator and coupled to receive second analog pixel signals. The first and second control modules are coupled to selectably switch bottom plates of the FCA from a low reference voltage to the high reference voltage at a same time as selectably switching bottom plates of the SCA from a high reference voltage to the low reference voltage. |
US08969771B2 |
Imaging system and imaging device
An imaging system includes an A/D converter including a holding unit holding a pixel signal as a voltage level, a comparator comparing the voltage level held with a reference level, a circuit capable of changing the voltage level so as to approach the reference level at first and second rates, wherein the voltage level is changed at the first rate to determine higher bits in accordance with inversion of a relationship between the reference level and the voltage level, after that, the voltage level is changed at the second rate to determine lower bits in accordance with inversion of the relationship between the reference level and the voltage level, and an adjusting unit which adjusts the voltage level during a period until the voltage level is changed at the second rate after determination of the higher bits so that the lower bits and the voltage level hold a linear relationship. |
US08969770B2 |
Correlated double sampling to include a controller to increment and invert a count during a first period and a second period
Apparatus and a method for correlated double sampling using an up-counter for parallel image sensors. All bits of a counter are set to one. An offset signal is compared to a first reference signal to define a first period during which the counter is incremented. After the first period, all bits of the counter are inverted. A sensor signal is compared to a second reference signal to define a second period during which the counter is incremented to generate a correlated double sampling value. |
US08969766B2 |
Systems and methods for controlling an adaptive heating system with exchangeable heat sources
An adaptive heating system for optimizing energy resources while heating a confined area. The adaptive heating system includes at least the following components: a controller, a first heat source, a switch device, and a wireline system. The wireline system is configured to connect the controller to the first heat source, a second heat source, and the switch device. The controller is configured to receive an input from the switch device, determine whether the input indicates a selection of the first heat source or a selection of the second heat source, and then initiate operation of either the first or the second heat source, based on the determined selection. The first heat source is associated with an electric heater and the second heat source is associated with a gas furnace. |
US08969765B2 |
Anti-icing system for radomes
An ice protection system for a structure has at least one electro-thermal heating element carried by the structure and a controller for selectively controlling the operation of each heating element. The controller operates each heating element according to a selected duty cycle defined by a pattern of time intervals, the controller selecting the duty cycle at least partially in response to measurements of ambient conditions about the structure. |
US08969760B2 |
System and method for manufacturing an airfoil
A system for manufacturing an airfoil includes a laser beam and a first fluid column surrounding the laser beam to create a confined laser beam directed at the airfoil. A gas flowing inside the airfoil disrupts the first fluid column inside the airfoil. A method for manufacturing an airfoil includes confining a laser beam inside a first fluid column to create a confined laser beam and directing the confined laser beam at a surface of the airfoil. The method further includes creating a hole through the surface of the airfoil with the confined laser beam, flowing a gas inside the airfoil, and disrupting the first fluid column with the gas flowing inside the airfoil. |
US08969758B2 |
Laser machining apparatus and method for forming a surface on an unfinished product
A method and apparatus for the laser machining of an unfinished object into a cutting tool with a cutting edge and a free surface. A laser generates laser beam impulses which are directed by a redirecting arrangement onto a surface of the unfinished object. An impulse reaches an impact location on the surface of the unfinished object under an inclination angle between the laser beam direction (R) of the impulse and the surface to be formed. The redirecting arrangement is controlled so that the laser beam impulses impact at adjacent impact locations and form a pulse zone. With a positioning arrangement a relative movement between the pulse zone and the unfinished object of predetermined speed is established so that the pulse zone formed by the impact locations moves along the surface of the unfinished object and an ablation layer of a layer thickness (dS) is removed with each contour pass. |
US08969757B2 |
Relief manufacturing apparatus and relief manufacturing method
A relief manufacturing apparatus includes: a laser beam irradiating device configured to irradiate laser beam on an engraving material; a scanning device configured to move at least one of the engraving material and the laser beam irradiating device; a numerical value acquiring device configured to acquire a numerical value including a first inclination angle indicating inclination of the inclined face of the relief; a control device configured to control the scanning device and the laser beam irradiating device so that the laser beam is irradiated on a surface of the engraving material to form an initial inclined face having a second inclination angle smaller than the first inclination angle and thereafter the laser beam is irradiated on the initial inclined face to enlarge the inclination of the inclined face from the second inclination angle to the first inclination angle. |
US08969756B2 |
Laser cutting system
A workpiece cutting apparatus includes a laser source, a first suction system, and a first finger configured to guide a workpiece as it moves past the laser source. The first finger includes a first end provided adjacent a point where a laser from the laser source cuts the workpiece, and the first end of the first finger includes an aperture in fluid communication with the first suction system. |
US08969754B2 |
Methods for automated application of hardfacing material to drill bits
Methods for depositing hardfacing material on portions of drill bits comprise providing a vertically oriented plasma transfer arc torch secured to a positioner having controllable movement in a substantially vertical plane. A rolling cutter is secured to a chuck mounted on an articulated arm of a robot. A surface of a tooth of the rolling cutter is positioned in a substantially perpendicular relationship beneath the torch. The torch is oscillated along a substantially horizontal axis. The rolling cutter is moved with the articulated arm of the robot in a plane beneath the oscillating torch. A hardfacing material is deposited on the tooth of the rolling cutter. |
US08969753B2 |
Plasma treatment installation
A plasma treatment installation including at least two stationary workpiece holders adapted for controlled rotation about their respective axis and having supporting plates for supporting workpieces for the treatment thereof, at least one hood to be set on a workpiece holder that is adapted to enclose each of a plurality of workpiece holders to form a sealed treatment space, and a manipulator for automatically equipping the supporting plates of a workpiece holder with workpieces, while the other workpiece holder is covered by the hood to perform the plasma treatment of the workpieces. |
US08969750B2 |
Method and apparatus for controlling electrode arms of a welding device
The invention relates to a compensation cylinder unit that acts as a drive for the electrode arms of a welding device. The unit comprises a cylinder and at least two pressure chambers, which are sub-divided by a piston assembly and which can be alternately supplied with a pressurized medium by means of a valve assembly for controlling the drive displacement. According to the invention, the valve assembly comprises a proportional valve which can be controlled by a control unit, first in accordance with harmonized path signals that represent the position of the piston assembly and then by pressure signals that respectively represent the pressure in the pressure chambers, in such a way that the difference between the pressures that prevail in the pressure chambers in a predeterminable position of the piston assembly assumes a constant value that represents the weight compensation force of at least one electrode arm. |
US08969749B2 |
Push and lock unit and input device using the same
A push & lock unit includes cam sections mounted on an outer wall of a rotary body that is disposed on an underside of an operating body, and each one of the cam sections contacts a saw-tooth section disposed on a lower end of a rib on an inner wall of a cover and a projection disposed at a bottom center of a housing in response to an up and down movement of the operating body, whereby the rotary body is rotated. When the operating body is pushed, a push face thereof is locked at a position almost flush with an outer face of a panel. When the operating body is pushed once more, it is released from the lock, and restores to a state where the operating body projects from the outer face of the panel. |
US08969741B2 |
Damming device for cable sealing
A damming device for a conductor in a cable gland connector is described herein. The damming device can include a first portion having a first thickness of a flexible elastomeric material disposed between a first diameter and a second diameter. The damming device can also include a second portion having a second thickness of the flexible elastomeric material disposed between a third diameter and the second diameter. The damming device can also include a hole having the third diameter. The first diameter is greater than the second diameter, and the second diameter is greater than the third diameter. Further, the first thickness is greater than the second thickness. The damming device can be disposed, under tension, within a slot formed between a top portion of a compound chamber and a bottom portion of a union body. |
US08969735B2 |
Flexible metal interconnect structure
A flexible metal interconnect structure for transmitting signals between IC devices in flexible electronic devices is formed between two compliant flexible material layers that are laminated together form a multi-layer flexible substrate. The interconnect structure is formed by two rows of spaced-apart conductive pads (metal islands) attached to the inside (facing) surfaces of the flexible material layers. Compliant micro-contact elements such as micro-springs provide sliding metal pressure contacts that maintain electrical connections between the islands during stretching of the composite sheet. Specifically, at least two micro-contact elements are attached to each metal island in one of the rows, with one element in sliding pressure contact with an associated first metal island in the opposing row and the second element in sliding pressure contact with an associated second metal island. The islands and sliding contacts can be patterned into high density traces that accommodate large strains. |
US08969733B1 |
High power RF circuit
The present invention is directed to an RF device that includes a ceramic layer characterized by a ceramic layer dielectric constant and includes an RF circuit arrangement having a predetermined geometry and predetermined electrical characteristics. The ceramic layer dissipates thermal energy generated by the RF circuit via substantially the entire ceramic surface area. A first dielectric layer comprises a thermoplastic material and has a predetermined first thickness and a first dielectric constant. The predetermined electrical characteristics of the RF circuit arrangement are a function of the ceramic layer dielectric constant. A relative softness of the thermoplastic material is a function of the RF device operating temperature. |
US08969730B2 |
Printed circuit solder connections
Printed circuits may be electrically and mechanically connected to each other using connections such as solder connections. A first printed circuit such as a rigid printed circuit board may have solder pads and other metal traces. A second printed circuit such as a flexible printed circuit may have openings. Solder connections may be formed in the openings to attach metal traces in the flexible printed circuit to the solder pads on the rigid printed circuit board. A ring of adhesive may surround the solder connections. The flexible printed circuit may be attached to the rigid printed circuit board using the ring of adhesive. An insulating tape may cover the solder connections. A conductive shielding layer with a conductive layer and a layer of conductive adhesive may overlap the solder joints. The conductive adhesive may connect the shielding layer to the metal traces on the rigid printed circuit board. |
US08969729B2 |
High-voltage bushing with conductive inserts for DC voltage and method for producing the bushing
A high-voltage bushing with conductive inserts for a DC voltage has a bushing body surrounding a high-voltage conductor and containing a paper insulation. The bushing body tapers conically, at least at one end region thereof, from a ground-potential-side location to a high-voltage-side end and is surrounded by an insulating barrier. In order to provide a high-voltage bushing of this type with a particularly good potential distribution, the outside of the bushing body is coated at least in the region of the at least one end region with a coating to form a coating layer, which has a greater electrical conductivity than the bushing body. |
US08969727B2 |
Battery module
A battery module including a plurality of rechargeable batteries each having terminals; and a connection member electrically connecting terminals of neighboring ones of the rechargeable batteries, wherein the connection member includes a terminal hole into which one of the terminals is inserted, and a mounting portion that protrudes inwardly at the terminal hole, and wherein each terminal includes a support portion contacting the mounting portion and supporting the mounting portion. |
US08969723B2 |
Electric junction box
The invention provides an electric junction box with an enhanced thermal insulation between neighboring part-receiving chambers without causing excessive increase in the size of a case. In order to attain the objective, there is provided an electric junction box, which includes a case provided with a case body, a lower cover coupled to the lower end of the case body, and first and second upper covers and coupled to the upper end of the case body. The case includes neighboring first and second part-receiving chambers and. A through-hole is located between the first and second part-receiving chambers and extends from an upper end of the case to a lower end of the case. The through-hole has an enlarging portion, which is disposed at a lower end thereof and has increasing cross-sectional area as approaching to the lower end of the through-hole. |
US08969722B2 |
Thermally tuned coaxial cable for microwave antennas
A coaxial cable, including an inner conductor and an outer conductor surrounding the inner conductor and a thermally responsive material positioned between the outer conductor and the inner conductor. The outer conductor is in a generally concentric relationship to the inner conductor and the inner and outer conductors are adapted to connect to an energy source. A thermal change in the thermally responsive material alters the generally concentric relationship between the outer conductor and the inner conductor. |
US08969721B2 |
Boom tip cover
A protector for a boom tip for use within an electrical power transmission system, the protector including: one or more walls having a boom tip enclosure side, an exterior side, and one or more terminal edges that define a boom tip entrance; and a guide shoulder contoured along the boom tip enclosure side to define an installation path for a part of the boom tip to contact and follow relative to the protector. A method of installing a protector on a boom tip for use within an electrical power transmission system, the method including: positioning the protector so that the boom tip is between one or more terminal edges of the protector, and a part of the boom tip is adjacent an initial portion of a guide shoulder contoured along a boom tip enclosure side of the protector; and advancing the protector into an installed position over the boom tip by allowing the part to follow an installation path defined by the guide shoulder. |
US08969719B2 |
Chalcogenide-based photovoltaic devices and methods of manufacturing the same
In one example embodiment, a method includes sputtering one or more absorber layers over a substrate. In a particular embodiment, the substrate is pre-heated to a substrate temperature of at least approximately 300 degrees Celsius prior to the sputtering and during the sputtering of each of one or more of the absorber layers, and the sputtering of at least one of the absorber layers is performed in a sputtering atmosphere having a pressure of at least 0.5 Pascals. Additionally, in a particular embodiment, the sputtering of at least one of the absorber layers comprises sputtering from a sputter target that comprises a chalcogenide alloy that comprises copper (Cu) and one or more of sulfur (S), selenium (Se), or tellurium (Te). |
US08969716B2 |
Photovoltaic device and method for producing a concentrator lens system
The invention relates to a photovoltaic device for direct conversion of solar energy into electrical energy, which comprises a concentrator lens system and at least one solar cell. Furthermore the invention relates to a method for producing a concentrator lens system which can be used in a corresponding photovoltaic device but also in other devices for, e.g. thermal, use of radiation. |
US08969713B2 |
Method of manufacturing photoelectric conversion device
Disclosed herein is a photoelectric conversion device having a semiconductor substrate including a front side and back side, a protective layer formed on the front side of the semiconductor substrate, a first non-single crystalline semiconductor layer formed on the back side of the semiconductor substrate, a first conductive layer including a first impurity formed on a first portion of a back side of the first non-single crystalline semiconductor layer, and a second conductive layer including the first impurity and a second impurity formed on a second portion of the back side of the first non-single crystalline semiconductor layer. |
US08969711B1 |
Solar cell employing nanocrystalline superlattice material and amorphous structure and method of constructing the same
A solar cell employing nanocrystalline superlattice material and amorphous structure and method of constructing the same provides improved efficiency when converting sunlight to power. The photovoltaic (PV) solar cell includes an intrinsic superlattice material deposited between the p-doped layer and the n-doped layer. The superlattice material is comprised of a plurality of sublayers which effectively create a graded band gap and multi-band gap for the superlattice material. The sublayers can include a nanocrystalline Si:H layer, an amorphous SiGe:H layer and an amorphous SiC:H layer. Varying the thickness of each layer results in an effective energy gap that is graded as desired for improved efficiency. Methods of constructing single junction and parallel configured two junction solar cells include depositing the various layers on a substrate such as stainless steel or glass. |
US08969706B2 |
Adhesive tape and solar cell module using the same
The present invention provides an adhesive tape 10 for electrically connecting a plurality of solar battery cells, which adhesive tape has a metal foil 1 and an adhesive layer 2 composed of an adhesive provided on at least one surface of the metal foil 1, and a solar battery module using the adhesive tape. The adhesive tape of the present invention can suppress the decrease in the product yield and can improve the connection workability of solar battery cells. |
US08969703B2 |
Distributed thermoelectric string and insulating panel
Inexpensive, lightweight, flexible heating and cooling panels with highly distributed thermoelectric elements are provided. A thermoelectric “string” is described that may be woven or assembled into a variety of insulating panels such as seat cushions, mattresses, pillows, blankets, ceiling tiles, office partitions, under-desk panels, electronic enclosures, building walls, refrigerator walls, and heat conversion panels. The string contains spaced thermoelectric elements which are thermally and electrically connected to lengths of braided, meshed, stranded, foamed, or otherwise expandable and compressible conductor. The elements and a portion of compacted conductor are mounted within the insulating panel On the outsides of the panel, the conductor is expanded to provide a very large surface area of contact with air or other medium for heat absorption on the cold side and for heat dissipation on the hot side. |
US08969702B2 |
Pickup unit of electric stringed instrument
A pickup unit of an electric stringed instrument is constituted of a vibrator supporting strings, a support which is installed inside the recess of a lower bridge so as to support the vibrator, and a plurality of piezoelectric elements which convert vibrations of strings transmitted thereto via the vibrator into electric signals. At least one presser member is interposed between the vibrator and the support. The presser member is constituted of a screw that is put into the lower surface of the vibrator from the lower surface of the support, thus upwardly pressing the piezoelectric elements onto the vibrator. This makes it possible to efficiently transmit vibrations of strings to the piezoelectric elements, thus improving the tone color and sound quality of an electric stringed instrument. |
US08969701B1 |
Musical instrument pickup with field modifier
A magnetic pickup for a stringed musical instrument with a secondary magnetic source that modifies the primary magnetic field distribution of the pickup. The secondary source comprises at least one permanent magnet and may further comprise a ferromagnetic loss component. A method for retrofitting and changing the tone of a pickup by attaching one or more secondary magnetic sources to the pickup. |
US08969697B2 |
Heel driven pedal apparatus
A heel driven pedal apparatus includes a base member and a footboard pivotally coupled to the base member. The footboard is pivotally movable between a released configuration at which the rear end is displaced from the base member and a compressed configuration at which the rear end is adjacent the base member. A spindle shaft includes a proximal end operatively coupled to the front end of the footboard with a linkage assembly, and an opposed distal end. A beater head is coupled to the distal end of the spindle shaft, the linkage assembly and the spindle shaft being configured to move the beater head toward a percussion instrument when the footboard is moved toward the compressed configuration and away from the percussion instrument when the footboard is moved toward the released configuration. The beater head is rotatable to position a desired beater head surface for contact with the percussion instrument. |
US08969695B1 |
System for controlling the tension and travel of a saxophone player's fingers
A saxophone having a body, a neck including a plurality of keys mounted thereon, each of said keys including an actuating surface and a bell including a valve protector, the improvement comprising a system for controlling the tension and travel of a saxophone player's fingers of both hands with a right hand device and a left hand device. The right hand device has an anchorage assembly mounted to the valve protector and a travel stopper elongated portion integrally extending from the anchorage assembly and kept at a substantially parallel and spaced apart relationship with respect to an actuating surface's plurality of keys thereby limiting the extension movement of a user's fingers as he or she actuates the keys. The left hand device includes an elongate stopper member with anchorage assemblies at its ends. The left hand device is rotatably mounted to facilitate its storage in storage cases. |
US08969692B2 |
Acoustic string tension compensating method and apparatus
An apparatus and method are disclosed for compensating for string tension acting upon the body of an acoustic instrument. An acoustic instrument incorporating the string tension compensating apparatus is also disclosed. |
US08969691B1 |
Extension block for a stringed instrument
A device is provided for assisting beginning players of an unfretted stringed instrument that can be removably attached to the shoulder of an unfretted stringed instrument and is sized such that the device extends out from the shoulder of the instrument a distance of approximately the distance between the first position and third position of the stringed instrument and such that its thickness is approximately the thickness of the body of the instrument. |
US08969690B1 |
Knee-rest for use with Indian classical violin
A violin knee-rest comprising a support with a connecting member attached. A rigid having an elongated opening member is attached to the connecting member. A sliding member is attached to a screw with a U shaped head and a screw thread. The sliding member is configured to slide across the rigid member through the first elongated opening. The sliding member having an elongated opening is configured to be fastened at a desired location on the sliding member by a first wing nut and a first washer arrangement. The violin receiving member has a first end which is threaded. The violin receiving member has a second end which is concave shaped to hold a base of the violin. The receiving member is configured to slide across the second elongated opening of the sliding member. The violin receiving member is configured to be fastened at a desired location on the sliding member. |
US08969688B2 |
Wheat cultivar WB6341
The invention relates to the wheat cultivar designated WB6341. Provided by the invention are the seeds, plants and derivatives of the wheat cultivar WB6341. Also provided by the invention are tissue cultures of the wheat cultivar WB6341 and the plants regenerated therefrom. Still further provided by the invention are methods for producing wheat plants by crossing the wheat cultivar WB6341 with itself or another wheat cultivar and plants produced by such methods. |
US08969683B2 |
Plants and seeds of hybrid corn variety CH213919
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH213919. The invention thus relates to the plants, seeds and tissue cultures of the variety CH213919, and to methods for producing a corn plant produced by crossing a corn plant of variety CH213919 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH213919. |
US08969677B2 |
Plants and seeds of corn variety CV721761
According to the invention, there is provided seed and plants of the corn variety designated CV721761. The invention thus relates to the plants, seeds and tissue cultures of the variety CV721761, and to methods for producing a corn plant produced by crossing a corn plant of variety CV721761 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV721761 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV721761. |
US08969672B2 |
Plants and seeds of sorghum variety GSV672338
The invention relates to the sorghum variety designated GSV672338. Provided by the invention are the seeds, plants and derivatives of the sorghum variety GSV672338. Also provided by the invention are tissue cultures of the sorghum variety GSV672338 and the plants regenerated therefrom. Still further provided by the invention are methods for producing sorghum plants by crossing the sorghum variety GSV672338 with itself or another sorghum variety and plants produced by such methods. |
US08969668B2 |
Pepper hybrid DRP 1630
The invention provides seed and plants of pepper hybrid DRP 1630 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of pepper hybrid DRP 1630 and the parent lines thereof, and to methods for producing a pepper plant produced by crossing such plants with themselves or with another pepper plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants. |
US08969665B1 |
Soybean cultivar S130091
A soybean cultivar designated S130091 is disclosed. The invention relates to the seeds of soybean cultivar S130091, to the plants of soybean cultivar S130091, to the plant parts of soybean cultivar S130091, and to methods for producing progeny of soybean cultivar S130091. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S130091. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S130091, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S130091 with another soybean cultivar. |
US08969659B2 |
Soybean cultivar AR0902412
The present invention is in the field of soybean variety AR0902412 breeding and development. The present invention particularly relates to the soybean variety AR0902412 and its progeny, and methods of making AR0902412. |
US08969658B2 |
Method for producing haploid, doubled haploid and/or dihaploid plants by gynogenesis
The invention relates to a method for producing haploid H, doubled haploid HD and/or dihaploid DH plants, the HD and DH being homozygous or essentially homozygous, this method being a method such as those which come under the technique of gynogenesis induced by irradiated pollen. This method comprises a step of irradiating the reproductive material of the male parent at a dose of between 160 and 190 gamma ray and/or a step of selecting the haploid H and/or DH plants by using one or more molecular marker(s). The invention also relates to a method for producing homozygous haploid, doubled haploid and/or dihaploid plants, comprising a step of determining the appropriate irradiation dose(s) for increasing the yields of said plants according to multiple given factors such as the plant species, the genotypes of the male parent and of the female parent, the climatic and weather conditions, the time at which the fruits are harvested, the level of growth of the embryos collected with a view to the culturing thereof, the level of development of the embryos placed in culture. Moreover, the invention concerns the molecular marker(s) used in the selection step and also the haploid embryos and the dihaploid embryos obtained by means of the method of the invention, and the progeny and the seeds of the plants obtained by means of the method of the invention. |
US08969656B2 |
Genes that increase plant oil and method for using the same
This invention is intended to be used to search for a transcription factor having novel functions of increasing the weight of an individual plant, increasing the weight of a given tissue per individual plant, or improving the productivity of a given substance per individual plant and to improve such properties in the plant. The weight of an individual plant is increased, the weight of a given tissue per individual plant is increased, the productivity of a given substance per individual plant is improved, or the content of a given substance per given tissue of a plant is increased via expression of a transcription factor that has been modified to suppress transcription accelerating activity. |
US08969655B1 |
Modulation of flavonoid content in cacao plants
Methods and materials for modulating (e.g., increasing or decreasing) flavonoid levels in cacao plants are disclosed. For example, nucleic acids encoding flavonoid-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also provided are methods for accelerating breeding of Theobroma cacao plants of the porcelana variety with modulated levels of proanthocyanidin, its precursors and it polymers, useful in various medical and skin care products. Also provided are plants having modulated flavonoid levels and plant products produced from plants having modulated flavonoid levels. |
US08969653B2 |
Extracellular vesicles derived from gram-positive bacteria, and use thereof
The present application relates to extracellular vesicles (EVs) derived from gram-positive bacteria. In detail, the present application provides animal models of disease using extracellular vesicles derived from gram-positive bacteria, provides a method for screening an active candidate substance which is capable of preventing or treating diseases through the animal models of disease, provides vaccines for preventing or treating diseases caused by extracellular vesicles derived from gram-positive bacteria, and provides a method for diagnosing the causative factors of diseases caused by gram-positive bacteria using extracellular vesicles. |
US08969651B2 |
Absorbent core
An absorbent core structure for disposable absorbent articles, having improved fluid handling properties. |
US08969649B2 |
Integrated dressing device
A device for the dressing of wounds and insertion sites of percutaneous and drug delivery devices provides 360 degree or complete circumferential protection of a wound or insertion site of a percutaneous or drug delivery device. In particular, the device is an integrated dressing for catheters comprising a pad and an adhesive dressing. |
US08969648B2 |
Blood clotting substrate and medical device
A blood clotting substrate and device which has a plurality of oxygen plasma-treated polypropylene pillars extending from the surface of a polypropylene film. |
US08969645B2 |
Process for reducing chloride in hydrocarbon products using an ionic liquid catalyst
We provide a process comprising: a. feeding a chlorinated-hydrocarbon and an ionic liquid catalyst to a treatment unit; b. operating the treatment unit at an elevated temperature to produce dechlorinated-hydrocarbon and HCl; and c. collecting the dechlorinated-hydrocarbon, wherein at least 90 wt % of the chlorides are removed. A second process comprises: a. creating an ionic liquid catalyst-rich zone in a distillation unit; b. passing chlorinated-hydrocarbon to the distillation unit; c. operating the unit under conditions causing removal of alkyl chloride to produce dechlorinated-hydrocarbon having a final boiling point close to a first final boiling point. A third process comprises: a. feeding alkylate gasoline blending component and ionic liquid catalyst to a treatment unit; b. operating the treatment unit; and c. collecting a dechlorinated-hydrocarbon, wherein at least 90 wt % of the chlorides have been removed and the dechlorinated-hydrocarbon has a second RON that is close to a first RON. |
US08969643B2 |
Method for conversion of aromatic hydrocarbons
A method of converting hydrocarbons requires contacting a hydrocarbon stream containing alkylated aromatic hydrocarbons with a catalyst of a phosphorus-containing pentasil zeolite in a reactor. The phosphorus-containing pentasil zeolite having a phosphorus content of 7.5% or less by weight of zeolite, a pore volume of at least 0.2 ml/g, and a 27Al MAS NMR spectrum characterized by a peak at or near 50 ppm that is greater than any other peak in said spectrum. A benzene-enriched output stream is recovered from the reactor. |
US08969641B1 |
Isomerization of tetrahyd rotricyclopentadienes to missile fuel
Tetrahydrotricyclopentadienes are isomerized to a low pour point, high energy missile fuel. Aluminum trichloride is the catalyst and an inert chlorinated hydrocarbon solvent is present. The mole ratio of AlCl3 to the diene is in the range between from about 0.005 to about 1.0. The isomerization temperature is in the range from between about −20° C. to about 25° C. |
US08969640B2 |
Dehydrogenation of alkanols to increase yield of aromatics
The present invention provides methods, reactor systems, and catalysts for increasing the yield of aromatic hydrocarbons produced while converting alkanols to hydrocarbons. The invention includes methods of using catalysts to increase the yield of benzene, toluene, and mixed xylenes in the hydrocarbon product. |
US08969638B2 |
Depolymerizatin of plastic materials
A styrene monomer reclamation process and system is described. The styrene monomer reclamation process includes providing a waste plastic. The waste plastic includes styrenic polymers. The waste plastic is formed into polymer particles. At least a portion of the polymer particles are dissolved in a solvent to form a polymer stream. The dissolved polymer particles are depolymerized to form a styrene monomer stream. |
US08969635B2 |
Alkane enhancement of waste using microbial pre-treatement
A method of: providing a mixture of fecal waste and a bacterium; incubating the mixture to produce a fatty acid enriched mixture; removing water from the fatty acid enriched mixture to produce a dried mixture; and pyrolyzing the dried mixture in an inert atmosphere to produce an alkane from the C5-C32 fatty acid. The bacterium is a type that produces a C5-C32 fatty acid in the presence of any microbes in the fecal waste. |
US08969632B2 |
Passivation of a homogeneous hydrogenation catalyst for the production of ethylene glycol
A process for making ethylene glycol by feeding reactants including 1,2-dioxygenated organic compounds, an organometallic homogeneous catalyst, and hydrogen to a hydrogenation reactor, reacting at least a portion of the reactants with hydrogen in the presence of the organometallic homogeneous catalyst to produce a reaction product mixture containing ethylene glycol, and passivating the catalyst by contacting the catalyst with a carbon monoxide to thereby suppress the formation of by-product diols other that the ethylene glycol primary product, and suppress the formation of by-product tetrols and by-product glycolaldehyde acetals; and separating at least a portion of the ethylene glycol from the reaction product mixture. |
US08969628B2 |
Method for enriching a homogeneous catalyst from a process flow
The invention relates to a method for enriching a homogenous catalyst from a process flow comprising said homogenous catalyst as a component, wherein the process flow is conducted over at least one membrane and wherein the membrane wholly or partially comprises a polymer that has planar polymer units connected to one another via a rigid link and wherein the linker is contorted, such that at least one planar polymer unit is connected to at least one second planar polymer unit via the link, in a non-co-planar arrangement. The invention furthermore relates to a method for producing tridecanal. |
US08969627B2 |
Method for producing 4,4'-diformyldiphenylalkane
A method for producing a 4,4′-diformyldiphenylalkane represented by the following formula (2), containing formylating a diphenylalkane represented by the following formula (1) with carbon monoxide in the presence of hydrogen fluoride and boron trifluoride, in which the reaction temperature of the formylation is from −50 to 5° C., from 5 to 30 mol of hydrogen fluoride is used per 1 mol of the diphenylalkane, and from 1.5 to 5 mol of boron trifluoride is used per 1 mol of the diphenylalkane: wherein R represents an alkanediyl group having from 1 to 6 carbon atoms, wherein R represents an alkanediyl group having from 1 to 6 carbon atoms. |
US08969625B1 |
Method for producing redox shuttles
A single step method for producing a redox shuttle having the formula 2,5-di-tert-butyl-1,4-phenylene tetraethyl bis(phosphate) is provided, the method comprising phosphorylating tert butyl hydroquinone with a phosphate-containing reagent. Also provided is method for producing 2,5-di-tert-butyl-1,4-phenylene tetraethyl bis(phosphate), the method comprising solubilizing tert-butyl hydroquinone and tetrabutylammonium bromide with methyltetrahydrofuran to create a mixture; heating the mixture while adding base to the mixture in an amount to turn the mixture orange; and adding diethyl chlorophosphate to the orange mixture in an amount to phosphorylate the hydroquinone. |
US08969622B2 |
Dendritic molecular intracellular transporters and methods of making and using same
In accordance with the purpose(s) of the invention, as embodied and broadly described herein, the invention, in one aspect, relates to compounds comprising the structure: and at least one guanidinium residue, wherein m is zero or a positive integer. Also disclosed are methods of preparing the disclosed compounds. Also disclosed are methods of intracellular delivery comprising administering the disclosed compounds and compositions to a subject. Also disclosed are pharmaceutical compositions comprising a therapeutically effective amount of one or more compounds or compositions of the invention and a pharmaceutically acceptable carrier. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
US08969618B2 |
Process for producing unsaturated aldehyde and/or unsaturated carboxylic acid
A catalyst and a catalyst packing schedule are designed so that a relation between the raw material conversion rate at which the yield of the objective product becomes maximum and the raw material conversion rate at which a high and low correlation between maximum temperature of the catalyst layer present closest to a reaction gas inlet side Zin and maximum temperature of the catalyst layer present closest to a reaction gas outlet side Zout is reversed satisfies a specific condition of 0.5≦Cmax−Ccrs≦5, in which Cmax: a raw material conversion rate at which yield of the objective products becomes maximum; and Ccrs: a raw material conversion rate at which, when maximum temperature of the catalyst layer Zin is regarded as Tin, maximum temperature of the catalyst layer Zout is regarded as Tout, and the raw material conversion rate is changed, a high and low correlation between Tin and Tout is reversed. |
US08969617B2 |
18β-Glycyrrhetinic acid derivatives and synthetic method thereof
The present invention provides a chemical compound having the structure being one selected from a group consisting of wherein R1 is one selected from a group consisting of COOCH3, COOCH2Ph, CONHCH(CH3)2 and CONHC6H5, R2 is one selected from a group consisting of H, CH3 and CH(CH3)2, R3 is one selected from a group consisting of H, CH3, CH(CH3)2 and CH2Ph, and R4 is one of CH(CH3)2 and C6H5. |
US08969616B2 |
Process for preparation of isosulfan blue
A process for the preparation of isosulfan blue (Active Pharmaceutical Ingredient) is provided. A process is also provided for preparation of the intermediate, 2-chlorobenzaldehyde-5-sulfonic acid, sodium salt of formula (2), used in the preparation thereof and a procedure for the isolation of benzaldehyde-2,5-disulfonic acid, di-sodium salt of the formula (3). Also provided is a process for the preparation of an isoleuco acid of formula (4), which upon mild oxidation gives rise to isosulfan blue of pharmaceutical grade which can be used for preparation of pharmaceutical formulations. The isolation and purification procedures provided in the process provide substantially pure isosulfan blue with HPLC purity 99.5% or greater. |
US08969613B2 |
Removal of aldehydes in acetic acid production
A system and method for removing acetaldehyde from an acetic acid system, including providing a solution from the acetic acid system, the stream having methyl iodide and acetaldehyde, and contacting the solution with an ion-exchange resin and/or liquid catalyst. |
US08969603B2 |
Oxidative cleavage of unsaturated carboxylic acids
Provided are processes for the oxidative cleavage of a double bond in an unsaturated carboxylic acid. The process includes contacting the unsaturated carboxylic acid with a mild oxidizing agent and agitating the unsaturated carboxylic acid and the mild oxidizing agent for a time sufficient to cleave a double bond of the unsaturated carboxylic acid and produce a product comprising an aldehyde. The process is typically carried out in a mill, such as a ball, hammer, attrition, or jet mill. |
US08969599B2 |
Cerium-containing zeolites and coke reduction methods
The invention provides a catalyst system for catalytic fast pyrolysis comprising a cerium-incorporated HZSM-5 zeolite (Catalyst 1), and methods of making and using the same. The invention also provides a process for reducing coke formation during catalytic fast pyrolysis of biomass using HZSM-5, wherein the process can include incorporating cerium into the HZSM-5 zeolite to produce Catalyst 1 prior to the catalytic fast pyrolysis. |
US08969597B2 |
Process for preparing nebivolol
The present invention relates to a process for preparing Nebivolol and, more in particular, to a fractional distillation method of a mixture of stereoisomers of formula intermediates useful in the preparation of nebivolol. |
US08969596B2 |
Synthesis of equol
Subject of the invention is a method for the production of isoflavanes from isoflavones, whereby in a first reaction step (a) the 4-keto group of the isoflavone is reduced in a enantioselective manner, whilst the 2,3-double bond is maintained, to the 4-hydroxy compound. |
US08969591B2 |
Method for producing cyclic sulfonic acid ester and intermediate thereof
The present invention is directed to provide an efficient production method which is capable of not only obtaining a cyclic sulfonic acid ester (sultone) at low cost and in high yield, but also the sulfonic acid ester (sultone) stably even in a commercial scale. The present invention relates to a method for producing hydroxysultone comprising a first step where a diol having a specified structure and a thionyl halide are reacted to obtain a cyclic sulfite having a specified structure, and a second step where the cyclic sulfite is reacted with water or/and alcohol; a method for producing an unsaturated sultone having a specified structure comprising a third step where a hydroxylsultone having a specified structure is reacted with an acid halide or an acid anhydride to obtain an intermediate, subsequently the intermediate is treated with a base; as well as a cyclic sulfite having a specified structure. |
US08969590B1 |
Autotaxin inhibitors
Classes of compounds that exhibit effective inhibition of autotaxin enzymes are provided. Such classes include thioureas, diphenyldiazerenes, xanthenes, and isoindoles and exhibit reactivity with autotaxin to ultimately reduce the size of the reactive sites thereon to prevent conversion of lysophosphatidyl choline to lysophophatidic acid. Furthermore, such compounds can be incorporated within delivery forms for human ingestion. As such, these compounds accord an excellent manner of potentially reducing generation of certain cancers attributable to the presence of naturally occurring autotaxin within the human body. Methods of inactivating autotaxin to certain degrees therewith such compounds are encompassed within invention as well. |
US08969589B2 |
Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response
The present invention provides a compound that is represented by the following general formula wherein R1, R2, R4, R5, R6, R7, X, W, X and Y are as defined in the specification. The compounds may be administered to treat DP1, FP, EP1, TP and/or EP4 receptor mediated diseases or conditions. |
US08969582B2 |
Preparation of febuxostat
Processes for preparing febuxostat. |
US08969579B2 |
Oxadiazole derivative, and light-emitting element, light-emitting device, electronic device, and lighting device using the oxadiazole derivative
An object of one embodiment of the present invention is to provide a novel oxadiazole derivative as a substance having high excitation energy, in particular, a substance having high triplet excitation energy. One embodiment of the present invention is an oxadiazole derivative represented by General Formula (G1) below. In General Formula (G1), R1 represents either an alkyl group having 1 to 4 carbon atoms or a substituted or unsubstituted aryl group having 6 to 13 carbon atoms. In General Formula (G1), R21 to R27 separately represent any one of a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, and a substituted or unsubstituted aryl group having 6 to 13 carbon atoms. In General Formula (G1), α represents a substituted or unsubstituted arylene group having 6 to 13 carbon atoms. In General Formula (G1), Z represents either a sulfur atom or an oxygen atom. |
US08969572B2 |
Process for preparing tetrazole-substituted anthranilamide derivatives and novel crystal polymorphs of these derivatives
The present invention relates to a process for preparing tetrazole-substituted anthranilamide derivatives of the formula (I) in which R1, R2, R3, R4, R5 and Z are each as defined in the description, and to a novel crystal polymorph of these derivatives and to the use thereof in agrochemical formulations. |
US08969567B2 |
Nitrogen containing compounds and their use
Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed. |
US08969564B2 |
Aryl ether-base kinase inhibitors
The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1. |
US08969560B2 |
Process for the carbonylation of ethylenically unsaturated compounds, novel carbonylation ligands and catalyst systems incorporating such ligands
A novel bidentate ligand of general formula (I) is described together with a process for the carbonylation of ethylenically unsaturated compounds. The group X1 may be defined as a univalent hydrocarbyl radical of up to 30 atoms containing at least one nitrogen atom having a pKb in dilute aqueous solution at 18° C. of between 4 and 14 wherein the said at least one nitrogen atom is separated from the Q2 atom by between 1 and 3 carbon atoms. The group X2 is defined as X1, X3 or X4 or represents a univalent radical of up to 30 atoms having at least one primary, secondary or aromatic ring carbon atom wherein each said univalent radical is joined via said at least one primary, secondary or aromatic ring carbon atom(s) respectively to the respective atom Q2. Q1 and Q2 each independently represent phosphorus, arsenic or antimony. |
US08969557B2 |
ACC inhibitors and uses thereof
The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same. |
US08969554B2 |
6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides
Disclosed are compounds exhibiting sufficient herbicidal activity at low application dosage when they are applied to soils and foliage, and an agrochemical composition using the same, in particular herbicides. The compounds are triazine derivatives represented by following Formula 1 or salts thereof, and the herbicides containing them: [Chem. 28] wherein in the formula, R1 represents a hydrogen atom; a C1-C12 alkyl group; a C2-C6 alkenyl group, etc., R2 represents a C1-C12 alkyl group, etc., Y and Z represent an oxygen atom or a sulfur atom, and A represents a 5- or 6-membered cyclic group which may contain a nitrogen atom, an oxygen atom, or a sulfur atom. |
US08969553B2 |
Method for producing N-sulfonyl-substituted oxindoles
Process for the selective N-sulfonylation of oxindoles, in particular process for the N-sulfonylation of 3-triazinyloxindoles, and also N-sulfonyl-substituted 3-triazinyloxindoles and the use of N-sulfonyl-substituted oxindoles and of N-sulfonyl-substituted 3-triazinyloxindoles as intermediates for the synthesis of fine chemicals and of active ingredients in the field of pharmacy and agriculture, and also the use of these compounds as active ingredients in the field of agriculture. |
US08969549B2 |
Antioxidant small molecules aimed at targeting metal-based oxidative stress in neurogenerative disorders
Amine chelates capable of antioxidant capacity and amyloid disaggregation are shown which may be useful in targeting metal-based oxidative stress in neurodegenerative disorders. Pyclen, a backbone commonly investigated for contrast agent imaging, may be repurposed as an anti-oxidant chelator for disaggregating amyloid. The antioxidant capacity of pyclen is enhanced dramatically via conversion of the pyridine backbone to a pyridol with cellular studies showing superior antioxidant capacity while retaining chelation ability to protect amyloid from metal ions aggregation and also disaggregate amyloid aggregates. Another family of molecules based upon hybrid heterocyclic amine ligands is also presented. |
US08969547B2 |
Method for preparing fluticasone furoate
Method for preparing fluticasone furoate (6α,9α-difluoro-11β-hydroxy-16α-methyl-17α-[(2-furoyl)oxy]-3-oxo-androsta-1,4-diene-17β-carbothioic acid S-fluoromethyl ester) by directly subjecting a compound of Formula III and a complex of a fluoromethylating reagent in presence of an organic base to a replacement reaction to obtain the target compound. Generation of impurities in a process via Compound IV is avoided; the method is simple with mild reaction conditions, suitable for industrial production, and yields products with purity of 98% by HPLC. |
US08969546B2 |
Compounds useful in imaging and therapy
Provided in the following specification are precursors or synthons that are useful for the synthesis of various arabinose based chemical and radiochemical derivatives of nitroimidazole-containing azomycin arabinosides, such as radioiodinated 1-#-D-(5-deoxy-5-[I*]-iodoarabinofuranosyl)-2-nitroimidazole (*IAZA), and radiofluorinated 1-#-D-(5-deoxy-5-[18F]-iodoarabinofuranosyl)-2-nitroimidazole (18FAZA). Such compounds are useful in imaging, therapy, or radiotherapy. Further, various syntheses of said precursors/synthons and the incorporation of said precursors/synthons into kits is provided. The precursors/synthons provided herein allow for an improved and facile manufacturing process for nitroimidazole-containing azomycin arabinosides. |
US08969544B2 |
Combined use of PRAME inhibitors and HDAC inhibitors
The invention relates to the cancer antigen PRAME (PReferentially expressed Antigen in MElanoma) and its use in a method of treatment of a tumour which comprises administering to a subject in need of treatment an effective amount of an inhibitor of PRAME, in combination with a second agent selected from the group of an inhibitor of HDAC (an HDACi) and a retinoid. |
US08969540B2 |
Tumor specific antibody
The present invention provides the amino acid and nucleic acid sequences of heavy chain and light chain complementarity determining regions of a tumor specific antibody. In addition, the invention provides tumor-specific antibodies and immunoconjugates comprising the tumor-specific antibody attached to a toxin or label, and methods and uses thereof. The invention also relates to diagnostic methods and kits using the tumor-specific antibodies of the invention. |
US08969539B2 |
Expression vectors
This present invention provides an expression vector system that uses alternative RNA processing to express in a single cell a polypeptide in both membrane-bound and soluble forms. By incorporating a mimetic structure of the 3′ terminal region of human mu gene and introducing other exogenous genetic elements, an artificial gene can be constructed that is capable of simultaneously expressing membrane-bound and secreted forms of polypeptides in myeloma cells and other cells of the B lymphocyte lineage, as well as in non-B cells. If an immunoglobulin heavy chain is co-expressed with a light chain using this vector, whole antibodies can be produced that are both displayed on the surface of a single cell and secreted into the cell culture supernatant. Membrane-bound antibodies facilitate isolation and expansion of those cells displaying antibodies with desired antigen binding characteristics, while secreted antibodies facilitate identification of antibodies having desired biological function(s). |
US08969538B2 |
Albumin fusion proteins
The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention. |
US08969537B2 |
Single-stranded nucleic acid aptamers specifically binding to E. coli
Provided are a single-stranded nucleic acid aptamer specifically binding to E. coli and a method for detecting E. coli using the same. The method, kits or sensors of the present disclosure enable E. coli to be specifically detected among microorganisms existing in a water system, but also be applied in fields such as food sanitation or medical diagnosis. |
US08969536B2 |
Torque teno virus (TTV) isolates and compositions
The present invention is directed to novel nucleotide and amino acid sequences of Torque teno virus (“TTV”), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine TTV genotypes and isolates. Diagnostic and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention, as are infectious clones useful in the propagation of the virus and in the preparation of vaccines. Particularly important aspects of the invention include vaccines that provide TTV ORF1 protein, or peptide fragments thereof, as antigen. |
US08969532B2 |
Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
The present invention provides processes for the manufacturing of polypeptide conjugates. In particular, the invention provides methods for the purification of polypeptide conjugates, which include at least one polymeric modifying groups, such as a poly(alkylene oxide) moiety. Exemplary poly(alkylene oxide) moieties include poly(ethylene glycol) (PEG) and poly(propylene glycol). In an exemplary process, hydrophobic interaction chromatography (HIC) is used to resolve different glycoforms of glycoPEGylated polypeptides. |
US08969528B2 |
Antibodies to hepatocyte growth factor activator
The invention provides methods and compositions for modulating hepatocyte growth factor activator function. |
US08969526B2 |
Antibody Fc variants
The invention relates to engineered polypeptides comprising Fc variants and their uses. More specifically, Fc variants are described exhibiting reduced effector function. These variants cause a benefit for a patient suffering from a disease which could be treated with an antibody for which it is desirable to reduce the effector function elicited by antibodies. |
US08969523B2 |
Sebum secretion-blocking composition, and food or beverage containing same
An object is to provide a sebum secretion inhibiting composition and a food or drink product using the same. The present inventors have conducted extensive studies and consequently found that the sebum secretion is inhibited by orally ingesting a collagen peptide, which is hydrolyzed collagen, and provide an oral sebum secretion inhibiting composition comprising a collagen hydrolysate and a food or drink product containing the composition. |
US08969522B2 |
Method for producing collagen-like polypeptide
An object is to provide a method for producing an ever-larger molecular weight collagen-like polypeptide single strand. Another object is to provide a method for controlling a molecular weight of a product to be obtained in desired magnitude upon producing a collagen-like polypeptide single strand. A solution is a method for producing a polypeptide including a step for allowing a condensation reaction of peptide oligomers represented by any one of formulas (1) to (3) (SEQ ID No:1 to SEQ ID No:3), wherein the condensation reaction is carried out in an aqueous solvent containing a phosphate ion in the range of 0 M to less than 0.01 M in the presence of a condensing agent, or a condensing agent and a condensing auxiliary: H-(Pro-Y-Gly)n-OH (1); H-(Y-Gly-Pro)n-OH (2); and H-(Gly-Pro-Y)n-OH (3); wherein, in formulas (1) to (3), Y is hydroxyproline or proline, and n is an integer from 1 to 10. |
US08969517B2 |
Method for processing vegetable raw materials
The inventive method for processing vegetable raw materials consisting in organic solvent-extracting said materials, isolating it by retention which is associated with cooling and wax filtration, separating free oxides from the thus obtained solution of extractive substances by alkali solution action, dividing the obtained neutralized solution into a neutral substance solution in the hydrocarbon solvent and a water-alkali solution of organic acid salts, acidifying said salt solution, isolating chlorophilline acids and a fatty and resin acid fraction therefrom by retention, dividing the sum of diterpenic and higher fatty acids, distilling the solvent from neutral substances and in dividing said neutral substances. The diterpenic and higher fatty acid sum is treated in a low-molecular alcohol by adding a sulphuric acid in the form of a catalyst. Said method also consists in distilling alcohol and neutralizing the diterpenic acids and catalyst, extracting the higher fatty acid ethers, acidifying the water-alkali solution and extracting isolated diterpenic acids, distilling said solvent and in producing a rodent repellent. The neutral substances are subsequently extracted into acetone and C1-C3 alcohol. Afterwards, during acetone treatment, the concentrates of higher fatty acid esters are produced in association with triterpenic alcohols, stearins, higher fatty alcohols and an acetone-soluble residue. During the residue treatment by alcohol, the sum of diterpenic acids is separated, and the saponification of said acids makes it possible to produce a polyprenol concentrate for separating polyprenols therefrom by chromatography. |
US08969511B2 |
Polyether block copolymers and compositions that can be obtained therefrom
Polyether block copolymers of the general structure B-(A-OH)n are described, where n is greater than or equal to 2 and blocks A are made up of polyoxypropylene units and the central block B of polyoxytetramethylene, polyoxyethylene, polybutadiene, polyisoprene, polyacrylate, polymethacrylate, polyamide, polyurethane, or polyester units. These polyether block copolymers are suitable for the manufacture of compositions that serve as the basis for preparations for use as a one-component moisture-hardening or two-component adhesive or sealant, for assembly bonding, for areal bonding, and/or for coating, as a reactive melt adhesive or as a laminating adhesive. |
US08969496B2 |
Method for controlling chain structure of copolymer
The present invention provides a method for controlling the chain structure of a copolymer. The disclosed method is capable of controlling the arrangement of monomeric units in a copolymer, and of selectively forming a random copolymer, tapered copolymer, multiblock copolymer and block copolymer. In the method for controlling the chain structure of a copolymer of a conjugated diene compound and a non-conjugated olefin, the introduction of the conjugated diene compound is controlled in the presence of the non-conjugated olefin so as to control the chain structure of the copolymer. |
US08969493B2 |
Process and apparatus for continuously polymerizing cationically polymerizable monomers
The present invention relates to a process and to an apparatus for continuous living polymerization of cationically polymerizable monomers, in which at least three feedstocks are mixed in one or more mixers with microstructures and then polymerized in at least one reaction zone. |
US08969492B2 |
Flourine-free aqueous dispersion for treating textile fabrics
Aqueous dispersions comprise a specific copolymer based on acrylate, a specific paraffin wax and one or more dispersants. The dispersions have high stability and are useful for treating textile fabrics, conferring outstanding water-repellent properties thereon. |
US08969491B2 |
Aqueous dispersion
An aqueous dispersion containing a vinylidene chloride polymer (P1) containing vinylidene chloride in a proportion of at least 50% by weight, and at least one random, alternating or gradient copolymer (C1) having: a) at least one monomer unit (m1) carrying at least one phosphonate group —PO(OH)(OR1) with R1 being a hydrogen atom or an alkyl radical comprising from 1 to 11 carbon atoms, and b) monomer units (m2) which represent at least 50% by weight of the copolymer (C1), derived from at least one monomer (M2) chosen from styrene, maleic anhydride, itaconic acid and the (meth)acrylic monomers corresponding to the general formula CH2=CR2R3 in which R2 and R3 are described herein, copolymer (C1) not containing monomer units derived from vinylidene chloride. |
US08969490B2 |
Epoxy resin composition, resin sheet, prepreg, multilayer printed wiring board and semiconductor device
An object of the present invention is to provide an epoxy resin composition that provides, when used for an insulation layer of a multilayer printed wiring board, a multilayer printed wiring board which is excellent in plating adhesion, heat resistance and moisture resistance reliability and capable of forming fine wiring. Another object of the present invention is to provide a resin sheet, a prepreg, a method for producing a multilayer printed wiring board, a multilayer printed wiring board and a semiconductor device.These objects are achieved by an epoxy resin composition comprising (A) an epoxy resin, (B) a phenoxy resin having a specific bisphenol acetophenone structure and (C) a curing agent, wherein the content of the phenoxy resin (B) is 10 to 30% by weight of the total solid content of the resin composition. |
US08969488B2 |
Method of mixing and device useful thereof
The invention generally relates to a method of substantially homogeneously mixing ingredients comprising solid thermoplastic particulates and a viscous material in a container and apparatus useful therein. The invention also generally relates to a non-clogging device and mixing apparatus comprising same. |
US08969487B2 |
Thermally stable oleophobic low adhesion coating for inkjet printhead face
A coating for an ink jet printhead front face, wherein the coating comprises an oleophobic low adhesion coating having high thermal stability as indicated by less than about 15 percent weight loss when heated to up to 300° C., and wherein a drop of ultra-violet (UV) gel ink or a drop of solid ink exhibits a contact angle of greater than about 45° and sliding angle of less than about 30° with a surface of the coating, wherein the coating maintains the contact angle and sliding angle after the coating has been exposed to a temperature of at least 200° C. for at least 30 minutes. In particular, the coating shows no oil on the coating surface after curing. |
US08969485B2 |
Surface induced ring-opening polymerization and medical devices formed therefrom
The present disclosure relates to coated biodegradable materials having a reduced amount of residual catalysts and methods thereof. |
US08969484B2 |
Methods of producing mono- and multi-functional polymers from terpene-based initiators
Provided herein are methods for the preparation of mono- and multi-functional telechelic polyolefins via polymerization reaction with a terpene-based initiator. |
US08969480B2 |
Polymer alloy and rubber product, and production method thereof
To provide a polymer alloy formed of a non-polar rubber and a polar rubber, and a rubber product, which are improved in ozone resistance (weather resistance) while having oil resistance and can achieve high mechanical strength (in particular, tensile strength), and a production method thereof.A rubber product in which an organic peroxide or other cross-linking agent is used to cross-link a polymer alloy comprising: a modified rubber in which EPDM, NR, or another non-polar rubber having a non-conjugated double bond is modified with 2-methoxy-1-naphthonitrile oxide, 2,6-dimethoxybenzonitrile oxide, or another nitrile oxide of an aromatic nitrile oxide derivative; and nitrile rubber, acrylic rubber, or another polar rubber. |
US08969478B2 |
Curable composition
Provided is a curable composition and its use. The curable composition may exhibit excellent processibility and workability. The curable composition has excellent light extraction efficiency, crack resistance, hardness, thermal and shock resistance and an adhesive property after curing. The curable composition may provide a cured product exhibiting stable durability and reliability under severe conditions for a long time and having no whitening and surface stickiness. |
US08969474B2 |
Thermoplastic acrylic resin composition
Provided is a thermoplastic acrylic resin composition comprising a methacrylic resin (A) and a polyvinyl acetal resin (B) obtained by acetalizing a polyvinyl alcohol resin with an aldehyde having 4 or more carbon atoms and an aldehyde having 3 or less carbon atoms in which the total amount of the vinyl alcohol units acetalized with the aldehyde having 4 or more carbon atoms and the aldehyde having 3 or less carbon atoms is 65 to 85 mol % of all repeating units, and the molar ratio of the vinyl alcohol unit acetalized with the aldehyde having 4 or more carbon atoms to the vinyl alcohol unit acetalized with the aldehyde having 3 or less carbon atoms is from 90/10 to 0/100. Furthermore, provided are an article molded from the thermoplastic acrylic resin composition and a method of producing the thermoplastic acrylic resin composition comprising the steps of mixing a methacrylic resin (A) and a polyvinyl acetal resin (B), increasing the resin temperature to 160° C. or more, and then decreasing the resin temperature to 120° C. or less. |
US08969471B2 |
Process for the preparation of dispersions of cross-linking agents in water
A process for the preparation of stable aqueous polycarbodiimide dispersions to be used as cross-linking agents, in which initially an isocyanate functional polycarbodiimide is prepared from a polyisocyanate and a mono- or polyisocyanate which contains a hydrophobic group. Thereafter the polycarbodiimide chain is capped and/or extended by reaction of the isocyanate functions or a part thereof with a hydrophilic amine- or hydroxy functional compound and of the remaining isocyanate functions with an amine- or hydroxy functional compound which contains hydrophobic groups, after which the obtained product is dispersed in water and the pH is adjusted to 9-14. The hydrophobic groups are hydrocarbons with 4-25 carbon atoms, fluorinated hydrocarbons, silicone functional hydrocarbons or polysilicones. Further, the invention relates to a coating mixture in which the polycarbodiimide dispersion is used as cross-linking agent and to the cured material obtained with the coating mixture. |
US08969470B1 |
Quantum dot-polymer nanocomposite for optical sensing
A quantum dot-polymer nanocomposite for optical chemical and biological sensing is formed by stably incorporating functionalized quantum dots into a pH sensitive hydrogel polymer network. At least one monomer of the pH sensitive hydrogel has functional groups selectively chosen to correspond to functionalized groups on the quantum dots to enable conjugation between the hydrogel polymer network and the functionalized quantum dots. The resulting quantum dot-polymer nanocomposite is placed in a solution having a known pH and addition of a chemical composition or biological agent of interest generates a change in pH of that solution. The nanocomposite expands or contracts responsive to the pH change. The pH change is optically detected by measuring the intensity level of fluorescence from the quantum dots when the nanocomposite is subjected to an excitation light source. |
US08969467B2 |
Materials having a controllable degree of crosslinking
The present invention relates to innovative materials which can be crosslinked by means of two different crosslinking mechanisms, the first crosslinking mechanism being an irreversible crosslinking. The second crosslinking mechanism is a thermoreversible mechanism.As a result of this thermoreversible change in the arc length, properties of the crosslinked material can be decisively changed and controlled, including flexibility, elasticity and other mechanical properties, but also chemical properties, the gas permeability and vapor permeability and storage capacity of the network. In this way it would be possible, for example, to store energy sources such as fuels. |
US08969459B2 |
White coating composition, and device employing coating made therefrom
The disclosure provides a white coating composition, and a device employing a coating made of the composition. The white coating composition includes 20-55 parts by weight of silicon dioxide particles, 40-75 parts by weight of inorganic material, and 5-40 parts by weight of silsequioxane, wherein the silsequioxane is prepared from monomers comprising a first monomer represented by the Formula (I) and a second monomer represented by the Formula (II) wherein, R1 is independently the same or different methyl or ethyl, and R2 is independently the same or different C1-6 alkyl. |
US08969456B2 |
Method of making a hot melt pressure-sensitive adhesive
A method of making a pressure-sensitive hot melt adhesive. The method includes extruding a melt composition that includes a polymer, wherein the polymer has acidic groups covalently attached thereto, and a metal salt hydrate, wherein the metal salt hydrate has a melting point that is less than the maximum processing temperature. |
US08969449B2 |
Discolour-free silanol condensation catalyst containing polyolefin composition
The present invention relates to a polyolefin composition comprising a crosslinkable polyolefin with hydrolysable silane groups and a silanol condensation catalyst, and (A) a compound containing one or more POm(OnR)(OoR)(OpR″) groups, wherein R, R′, and R″ are the same or different organic residues; m is 0 or 1; n, o, and p each are 0 or 1; and n+o+p=1 to 3; a master batch for a crosslinkable polyolefin composition comprising a polymer and a silanol condensation catalyst and component (A), a stabilized polyolefin containing cross-linked silane groups wherein cross-linking has been performed by the use of a silanol condensation catalyst, further comprising component (A), and to the use of component (A) for stabilizing a polyolefin composition comprising a crosslinkable polyolefin with hydrolysable silane groups and a silanol condensation catalyst. The polyolefin composition of the invention can be used for pipe, wire & cable, film, fiber and molding applications. |
US08969448B2 |
PC/ABS compositions having a good resistance to heat and chemicals
The present invention relates to moulding compositions of polycarbonates and graft polymers and optionally further additives and components, which have, in addition to a high resistance to chemicals, a good resistance to heat, in particular a low tendency towards yellowing and a low tendency towards degradation when exposed to heat.In a particular, flameproofed embodiment, the after-burn time in a UL94 classification is furthermore reduced. |
US08969446B2 |
Flame retardant polyurethane composition
The present invention is a flame-retardant polyurethane composition comprising (a) a thermoplastic polyurethane-based resin component, (b) a phosphorus flame retardant particulate filler, and (c) a low melting temperature phosphorus flame retardant agent. |
US08969441B2 |
Cationic microfibrillated plant fibre and manufacturing method for same
The present invention provides a novel cationized microfibrillated plant fiber and a method for manufacturing the same. A cationic microfibrillated plant fiber that is cationically modified with a quaternary-ammonium-group-containing compound, and that has an average diameter of 4 to 200 nm. |
US08969438B2 |
Pigment concentrate
Non-aqueous pigment concentrate comprising one or more pigments, one or more dispersants, and at least one resin, characterized in that the resin is a polyester comprising at least one oligo-ester building block with a hydrophobic tail linked thereto, wherein the hydrophobic tail is selected from the group consisting of: (a) branched hydrocarbons, (b) hydrocarbons containing a cyclic group, and (c) linear hydrocarbons, provided that when said linear hydrocarbon is linked to the oligo-ester building block via an ester group, the linear hydrocarbon contains 3 to 12 carbon atoms. |
US08969435B2 |
Method and apparatus for enhanced minimal shear molding utilizing extrusional, pelletization, and melt rheological control of pellets and micropellets and molded objects made therefrom
The present invention relates to a method for enhancement of the minimal shear molding process utilizing pellets and/or micropellets produced through controlled extrusional and pelletization processes in combination with nonpowder melt flow rheology that incorporates reduced molding temperature and/or reduced cure time, reduced rotation axis ratios and/or reduced rotation rates. Molding can be uniaxial, biaxial, or multiaxial rotational or oscillatory or both. The molded items produced can be single or multiple layers and can be produced in one or more molding sequences using similar or different chemical compositions. |
US08969433B2 |
Thermoplastic compositions, method of manufacture, and articles therefrom
This disclosure relates to thermoplastic compositions, in particular polycarbonate thermoplastic compositions containing a surface-treated talc, methods for the manufacture of such compositions, and articles formed from the compositions. |
US08969432B2 |
Modified polytetrafluoroethylene particles, method for producing the same, and modified polytetrafluoroethylene molded product
Provided are modified polytetrafluoroethylene particles having excellent moldability and processability. The modified polytetrafluoroethylene particles each have a core-shell structure that includes a particle core and a particle shell, the particle core having repeating units of tetrafluoroethylene and a comonomer (a), the particle shell having repeating units of tetrafluoroethylene and a comonomer (b), the comonomer (a) being a (perfluoroalkyl)ethylene represented by the following formula (I): CH2═CH—Rf (I) wherein Rf represents a C1 to C10 perfluoroalkyl group, the comonomer (b) being at least one monomer selected from the group consisting of 1,1,3,3,3-pentafluoro-1-propylene and 1,2,3,3,3-pentafluoro-1-propylene. |
US08969427B2 |
Surface modification method and surface-modified elastic body
The present invention aims to provide a surface modification method for a rubber vulcanizate or a thermoplastic elastomer, which can impart excellent sliding properties and excellent durability against repeated sliding motion and can allow the surface to maintain the sealing properties, without using expensive self-lubricating plastics. The present invention relates to a surface modification method for modifying a rubber vulcanizate or a thermoplastic elastomer as an object to be modified, the method including: step 1 of forming polymerization initiation points on the object to be modified; step 2 of radically polymerizing a monomer, starting from the polymerization initiation points, by irradiation with LED light at 300 nm to 400 nm to grow polymer chains on a surface of the object to be modified; and step 3 of esterifying, transesterifying or amidating side chains of the polymer chains. |
US08969424B2 |
Anion exchange membranes and process for making
Embodiments of the present invention provide for anion exchange membranes and processes for their manufacture. The anion exchange membranes described herein are made the polymerization product of at least one functional monomer comprising a tertiary amine which is reacted with a quaternizing agent in the polymerization process. |
US08969423B2 |
Process for the production of substitute natural gas
In a process for the production of substitute natural gas, a feed gas is provided to a first and/or second and/or subsequent bulk methanator. The feed gas is subjected to methanation in the presence of a suitable catalyst. An at least partially reacted stream from the first bulk methanator is removed and supplied to the second and/or subsequent bulk methanator where it is subjected to further methanation. A product stream from the final bulk methanator is passed to a trim methanator train where it is subjected to further methanation. A recycle stream is removed downstream of the first, second or subsequent bulk methanator, and, in any order, passed through a compressor, subjected to cooling and then supplied to a trim and/or recycle methanator for further methanation before being recycled to the first and/or second and/or subsequent methanator. |
US08969420B2 |
Treatment of pervasive developmental disorders with redox-active therapeutics
Methods of treating or suppressing pervasive developmental disorders (PDDs) including; autistic disorder, Asperger's syndrome, childhood disintegrative disorder (CDD), Rett's disorder, and PDD—not otherwise specified (PDD-NOS) or attention deficit/hyperactivity disorder (ADHD) comprising administering to a subject in need thereof a therapeutically effective amount of one or more compounds as disclosed herein. |
US08969412B2 |
Use for a composition comprising chloroprocaine HCL, a new composition comprising chloroprocaine HCL and a method for its manufacture
The present invention concerns a new use for a composition containing chloroprocaine HCl, and in particular its use for the manufacture of a drug for intrathecal narcosis. The present invention also concerns a new composition containing chloroprocaine HCl, being particularly suited to this new use, as well as a new method for manufacturing the composition. |
US08969410B1 |
Pharmaceutical composition for alleviating or treating gout and uses thereof
A pharmaceutical composition for alleviating or treating gout and the applications thereof are provided. The pharmaceutical composition includes p-coumaryl diacetate as an active ingredient. |
US08969409B2 |
Treatment for pulmonary hypertension
One embodiment relates to a method of treating pulmonary hypertension based upon co-administering to a subject in need thereof a pharmaceutically effective amount of an oral therapeutic agent for treating pulmonary hypertension and a pharmaceutically effective amount of an inhaled therapeutic agent for treating pulmonary hypertension. The benefit of the co-administration of these agents is to eliminate or reduce one or more side effects associated with mono-therapy of either agent, as well as one or more side effects associated with other administration routes such as subcutaneous or intravenous administration. |
US08969408B2 |
Use of lignan-type compounds or extract of nutmeg or aril of nutmeg comprising the same
The present invention relates to a new use of lignan-type compounds or an extract of nutmeg or aril of nutmeg comprising the same. More particularly, the present invention relates to a composition for skin whitening comprising a lignan-type compound or an extract of nutmeg or aril of nutmeg comprising the same. Because the lignan compound represented by Chemical Formulas 1 to 3 or the extract of nutmeg or aril of nutmeg has superior skin whitening activity by inhibiting melanin production and tyrosinase activity, it can be used for the preparation of a cosmetic composition, food composition or pharmaceutical composition for skin whitening. |
US08969403B2 |
Crystalline forms of a 3-[2-methanesulfonyl-1-(4-trifluoromethyl-phenoxy)ethyl]pyrrolidine compound
The invention provides crystalline hydrochloride salts of (S)-3-[(S)-2-methanesulfonyl-1-(4-trifluoromethylphenoxy)ethyl]pyrrolidine. This invention also provides pharmaceutical compositions comprising the crystalline salts, processes and intermediates for preparing the crystalline salts, and methods of using the crystalline salts to treat diseases. |
US08969402B2 |
Combined acetylcholinesterase inhibitor and quaternary ammonium antimuscarinic therapy to alter progression of cognitive diseases
A method administers quaternary ammonium anti-cholinergic muscarinic receptor antagonists in combination with acetyl-cholinesterase inhibitors to treat either cognitive impairment or acute delirium. This therapy results in a modification of a cognitive disorder or disease, namely a slow down in the disease progression. In one preferred embodiment, the disease is dementia with Lewy Bodies. New formulations for quaternary ammonium anti-cholinergic muscarinic receptor antagonists are also disclosed. |
US08969401B2 |
Sulfonylpyrroles
Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors. |
US08969400B2 |
Pharmaceutical compositions of 5-hydroxytryptophan and serotonin-enhancing compound
This invention relates to novel pharmaceutical compositions comprising a therapeutically effective amount of a slow-release formulation of 5-hydroxytryptophan (5-HTP) and a serotonin-enhancing compound. The pharmaceutical compositions for use according to the invention are contemplated particularly useful for combating CNS disorders, including depressive disorders, bipolar disorders, anxiety disorders, obesity and pain. |
US08969392B2 |
Pesticide composition comprising propamocarb-fosetylate and an insecticidally active substance
The present invention relates to a pesticide composition intended for protecting plants, crops or seeds against phyto-pathogenic fungi or damaging insects, and the corresponding methods of treatment using the said composition. More precisely, the subject of the present invention is a pesticide composition based on propamocarb-fosetylate, an insecticide active substance and optionally a further fungicide active substance. |
US08969377B2 |
Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
The present disclosure is directed to compounds of the structure (X): wherein: n is 2 or 3; NHE has the structure wherein: R1 is H or —SO2—NR7R8—; R2 is selected from H, —NR7(CO)R8, —SO2—NR7R8— and —NR7R8; R3 is hydrogen; R7 is hydrogen; R8 is a bond linking to L; L is a polyalkylene glycol linker; and Core has the following structure: wherein: X is selected from the group consisting of a bond, —O—, —NH—, NHC(═O)—, —NHC(═O)NH— and —NHSO2—; and Y is selected from the group consisting of a bond, optionally substituted C1-6 alkylene, optionally substituted benzene, pyridinyl, a polyethylene glycol linker and —(CH2)1-6O(CH2)1-6—, and methods of using such compounds for the treatment of irritable bowel syndrome, chronic kidney disease and end-stage renal disease. |
US08969375B2 |
CDK9 kinase inhibitors
Disclosed are compound of Formula (Ia), wherein R1A, R1, R2, R10, J, L, T, X, Y, and Z are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds may be used as agents in the treatment of diseases, including cancer. Also provided are pharmaceutical compositions, comprising one or more compounds of Formula (Ia). |
US08969374B2 |
Iso-ergoline derivatives
Provided herein are novel iso-ergoline derivatives and compositions thereof. In other embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders such as, for example, migraine using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of agonizing receptors such as, for example, the 5-HT1D and/or the 5-HT1B receptor, without agonizing the 5-HT2B receptor using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing or inhibiting activity at receptors such as, for example, the adrenergic alpha2A and/or the alpha2B receptors using the compounds and compositions disclosed herein. |
US08969373B2 |
HCV protease inhibitors
A compound of general formula (I); A is O, S, CH, NH or NR′, when O links with Z3, Z1 is N or CRZ1, Z2 is CRZ2, when Z1 links with O, Z2 is CH, Z3 is C—Ar; Ra, Rb, Rc and Rd independently is H, OH, halogen or —Y1—Rm; A1 is NH or CH2; R1′ is alkyl, aryl, cycloalkyl, heterocycloalkyl or heteroaryl; A2 is N, O or linking bond; R1 is hydrogen, or, R1 linking covalently with R3 forms C5-C9 saturated or unsaturated hydrocarbon chain substituted by O or N; R3 is alkyl, cycloalkyl, heterocycloalkyl, alkyl substituted by cycloalkyl etc; R4 is alkoxy-CO, alkyl-NHCO, (alkyl)2NCO, or formyl substituted by aryl, cycloalkyl, heterocycloalkyl. |
US08969366B2 |
Substituted pyrimidinylpyrrolopyridinone derivatives, process for their preparation and their use as kinase inhibitors
Pyrimidinylpyrrolopyridinone derivatives of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer. |
US08969364B2 |
Inhibitors of catechol O-methyl transferase and their use in the treatment of psychotic disorders
The present invention relates to 4-pyridinone compounds which are inhibitors of catechol O-methyltransferase (COMT), and are useful in the treatment and prevention of neurological and psychiatric disorders and diseases in which COMT enzyme is involved. The present invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which COMT is involved. |
US08969363B2 |
Heterocyclic compounds and uses thereof
Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. |
US08969359B2 |
Gyrase and topoisomerase IV inhibitors
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti-bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity. |
US08969357B2 |
Methods for treating HCV
The present invention features interferon-free therapies for the treatment of HCV. Preferably, the treatment is over a shorter duration, such as no more than 12 weeks. In one aspect, the therapies comprise administering at least two direct acting antiviral agents and ribavirin to a subject with HCV infection. For example, the therapies comprise administering to the subject effective amounts of therapeutic agent 1, therapeutic agent 2 (or therapeutic agent 3), an inhibitor of cytochrome P450 (e.g., ritonavir), and ribavirin. |
US08969355B2 |
1-[2-(2,4 dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1a activity for the treatment of cognitive impairment
This disclosure relates to a method of treating a disease selected from the group consisting of affective disorders, depression, major depressive disorder, anxiety, general anxiety disorder, social anxiety disorder, obsessive compulsive disorder, panic disorder, and panic attacks. The method includes administering a therapeutically effective amount of Compound I or a pharmaceutically acceptable salt thereof to a patient in need thereof, in which Compound I is 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine. |
US08969354B2 |
Fatty acid fumarate derivatives and their uses
The invention relates to Fatty Acid Fumarate Derivatives; compositions comprising an effective amount of a Fatty Acid Fumarate Derivative; and methods for treating or preventing cancer, a metabolic disorder or neurodegenerative disorder comprising the administration of an effective amount of a Fatty Acid Fumarate Derivative. |
US08969353B2 |
Aminoalcohol lipidoids and uses thereof
Aminoalcohol lipidoids are prepared by reacting an amine with an epoxide-terminated compound are described. Methods of preparing aminoalcohol lipidoids from commercially available starting materials are also provided. Aminoalcohol lipidoids may be prepared from racemic or stereochemically pure epoxides. Aminoalcohol lipidoids or salts forms thereof are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the amino moiety of these aminoalcohol lipidoid compounds, they are particularly suited for the delivery of polynucleotides. Complexes, micelles, liposomes or particles containing the inventive lipidoids and polynucleotide have been prepared. The inventive lipidoids may also be used in preparing microparticles for drug delivery. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings. |
US08969352B2 |
Substituted 2-azabicycles and their use as orexin receptor modulators
The present invention is directed to compounds of Formula I: wherein X is N or CR1; Y is N or CR2; R1 is H, alkoxy, halo, triazolyl, pyrimidinyl, oxazolyl, isoxazole, oxadiazolyl, or pyrazolyl; R2 is H, alkyl, alkoxy, or halo; Z is NH or O; R3 is H, alkyl, alkoxy, halo, or triazolyl; R4 is H or alkyl; or R3 and R4, together with the atoms to which they are attached, form a 6-membered aryl ring or a 5- or 6-membered heteroaryl ring; R5 is pyridyl, pyrazinyl, or pyrimidinyl, wherein the pyridyl, pyrazinyl, or pyrimidinyl is optionally substituted with halo or alkyl; and n is 1 or 2. Methods of making the compounds of Formula I are also described. The invention also relates to pharmaceutical compositions comprising compounds of Formula I. Methods of using the compounds of the invention are also within the scope of the invention. |
US08969350B2 |
Pharmaceutical product comprising a p38 kinase inhibitor and a second active ingredient
The invention provides a pharmaceutical product, kit or composition comprising a first active ingredient which is N-Cyclopropyl-3-fluoro-4-methyl-5[3-[[1-[2-[2-(methylamino)ethoxy]phenyl]cyclopropyl]amino]-2-oxo-1(2H)-pyrazinyl]-benzamide or a salt thereof, and a second active ingredient selected from: a non-steroidal Glucocorticoid Receptor (GR Receptor) Agonist; an antioxidant; a β2 adrenoceptor agonist; a CCR1 antagonist; a chemokine antagonist (not CCR1); a corticosteroid; a CRTh2 antagonist; a DPI antagonist; an Histone Deacetylase activator; an IKK2 kinase inhibitor; a COX inhibitor; a lipoxygenase inhibitor; a leukotriene receptor antagonist; a MABA compound; an MPO inhibitor; a muscarinic antagonist; a PDE4 inhibitor; a PPARγ agonist; a protease inhibitor; a Statin; a thromboxane antagonist; a vasodilator; or, an ENAC blocker (Epithelial Sodium-channel blocker); and its use in the treatment of respiratory disease. |
US08969347B2 |
Compounds and methods for treating inflammatory and fibrotic disorders
Disclosed are compounds and methods for treating inflammatory and fibrotic disorders, including methods of modulating a stress activated protein kinase (SAPK) system with an active compound, wherein the active compound exhibits low potency for inhibition of the p38 MAPK; and wherein the contacting is conducted at a SAPK-modulating concentration that is at a low percentage inhibitory concentration for inhibition of the p38 MAPK by the compound. Also disclosed are derivatives and analogs of pirfenidone, useful for modulating a stress activated protein kinase (SAPK) system. |
US08969334B2 |
Nitrogen containing compounds and their use
Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed. |
US08969330B2 |
Steroids as agonists for FXR
The invention relates to compounds of formula (I): wherein R is ethyl, propyl or allyl, and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof. The compounds of formula (I) are useful as FXR agonists. |
US08969327B2 |
Substituted androst-4-ene diones
The disclosure relates to novel C4 and C6 substituted androst-4-ene diones as well as andros-1,4-diene diones and derivatives thereof, their process of preparation, pharmaceutical compounds containing them, and the use of said compounds for the treatment of hormone-related disorders in mammals. This includes hormone-dependent cancers, particularly those caused by elevated levels of estrogen and its intermediates. These compounds can also be used in the treatment of other hormone-related disorders, including benign prostatic hyperplasia, cardiovascular disease, and neurodegenerative disorders. |
US08969326B2 |
Estrogen antagonists as treatments for sclerosing disorders
The present invention relates to methods and compositions for treating a subject suffering from a sclerosing disorder, comprising administering, to the subject, an effective amount of an estrogen receptor antagonist (“ERANT”), wherein said ERANT has essentially no estrogen receptor agonist activity under physiologic conditions. |
US08969325B2 |
TRPV1 antagonists
Disclosed herein are compounds of formula (I): or pharmaceutically acceptable salts thereof, wherein X1, L, Rx, Ry, G, Z, A, m, n, and p are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed. |
US08969323B2 |
Priming solutions for cardiopulmonary bypass
The present invention relates to priming solutions used during cardiopulmonary bypass procedures. In particular, the present invention relates to a cardiopulmonary bypass priming solution comprising a balanced salt solution and a combination of oncotic and non-oncotic dextran molecules. The present invention also relates to the use of the priming solution in a cardiopulmonary bypass method, a method of maintaining oncotic pressure in a patient during a cardiopulmonary bypass procedure, and a combination of cardiopulmonary bypass priming solution and cardiopulmonary bypass apparatus. |
US08969321B2 |
Medical and nutritional applications of highly refined cellulose
The present invention provides a method for using processed cellulose. Preferably, the processed cellulose is a highly refined cellulose (HRC). The HRC is useful in a number of medical and nutritional applications. These medical and nutritional applications can include, but are not limited to, administering effective amounts of the HRC for lowering values of risk factor measurements for such diseases as arteriosclerotic cardiovascular disease and diabetes. Treatment of other diseases and conditions with the HRC is also possible. |
US08969320B2 |
Hyaluronic acid derivatives containing groups able to release NO
Disclosed are hyaluronic acid derivatives functionalized with S-nitrosothiol groups of the general formula: wherein HA indicates hyaluronic acid and G indicates a suitable spacer. |
US08969314B2 |
Methods for use in modulating miR-122a
Methods are provided for the treatment of cardiovascular or metabolic diseases characterized by elevated serum total cholesterol, elevated serum LDL-cholesterol, or elevated serum triglycerides, through the administration of an oligomeric compound which modulates the levels or activity of miR-122a. Further provided are methods for reducing hepatic steatosis or liver tissue triglyceride accumulation through the administration of an oligomeric compound which modulates the levels or activity of miR-122a. Such methods employ oligomeric compounds which hybridize with or sterically interfere with nucleic acid molecules comprising or encoding miR-122a. Such oligomeric compounds may include one or more modifications thereon, which may improve the activity, stability, or nuclease resistance of the oligomeric compound. These modified oligomeric compounds are used as single compounds or in compositions, including pharmaceutical compositions, to modulate or mimic the targeted nucleic acid comprising or encoding miR-122a. |
US08969312B2 |
Low side effect pharmaceutical composition containing antituberculosis drugs
A pharmaceutical composition for treating tuberculotic diseases with no side effect/low side effect is provided by the present invention, which pharmaceutically effective amount of one or more compounds chosen from isoniazid, rifampin, pyrazinamide and ethambutol, and pharmaceutically effective amount of substances which can reduce the side effect of the antituberculosis agents. |
US08969308B2 |
Treatment of T-cell mediated diseases
The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of synthesizing diketopiperazines and pharmaceutical compositions comprising certain diketopiperazines. The invention further provides methods of making improved pharmaceutical compositions of proteins and peptides by either increasing or decreasing the content of diketopiperazines in the compositions and the resultant improved pharmaceutical compositions. |
US08969304B2 |
Compositions and methods for the prevention of cancer in high risk patients
This relates to the prevention of cancer initiation. More specifically, the invention provides compositions and methods useful for altering the genetic signature in breast tissue, said alteration being correlated with a reduced risk for the development of breast cancer. |
US08969302B2 |
Low frequency glatiramer acetate therapy
A method of alleviating a symptom of relapsing-remitting multiple sclerosis in a human patient suffering from relapsing-remitting multiple sclerosis or a patient who has experienced a first clinical episode and is determined to be at high risk of developing clinically definite multiple sclerosis comprising administering to the human patient three subcutaneous injections of a therapeutically effective dose of glatiramer acetate over a period of seven days with at least one day between every subcutaneous injection so as to thereby alleviate the symptom of the patient. |
US08969296B2 |
TGFP-CAP peptide and its uses
The present invention relates to a GFP-CAP peptide having an amino acid sequence derived from TGF-β1 (transforming growth factor-β1) and a cell adhesion sequence, wherein the amino acid sequence derived from TGF-β1 consists of the amino acid sequence of SEQ ID NO:1 and the TGFP-CAP peptide is represented by the following formula I: Ile-Trp-Ser-Leu-Asp-Thr-Gln-Tyr-Cell adhesion sequence (I). The TGFP-CAP peptide of the present invention exhibits excellent anti-angiogenic activity. In addition, the TGFP-CAP peptide of the present invention prevents effectively melanin generation in skin to have skin whitening effects. The present peptide shows much higher stability and permeability to skin than natural-occurring TGF-β1. Such plausible activities and safety of the present peptide enable advantageously to application to drugs, quasi-drugs and cosmetics. |
US08969295B2 |
Identifying and modulating molecular pathways that mediate nervous system plasticity
The present invention provides methods for identifying genes and pathways involved in plasticity. The invention applies some of these methods to identify genes that are differentially regulated in at least a portion of the nervous system of an individual subjected to conditions known to result in altered nervous system plasticity, i.e., dark rearing (DR) or monocular deprivation (MD). The genes are targets for pharmacological agents that modify plasticity. The invention also identifies biological pathways that are enriched in genes that are differentially regulated under conditions known to result in altered nervous system plasticity. The present invention further provides methods and compositions for modifying plasticity in the nervous system of a subject. The invention includes a method for modifying plasticity in the nervous system of a subject comprising administering a plasticity-modifying agent to the subject, wherein the plasticity-enhancing agent modulates a gene or pathway that is differentially regulated in developmental conditions that alter nervous system plasticity (e.g., DR or MD). The methods and compositions may be administered to a subject suffering from damage to the nervous system or from a neuropsychiatric disorder in order to enhance recovery, reorganization, or function of the nervous system. The methods optionally include administering a proteolysis-enhancing agent to the subject. |
US08969291B2 |
Methods for decreasing leptin levels or activity for treating inflammation
The present invention is directed to methods for modulating the Th1 /Th2 cell balance toward anti-inflammatory cytokine producing cells in a subject comprising decreasing the amount, the expression, or the activity of leptin in a subject sufficient to modulate the Th1 /Th2 cell balance toward anti-inflammatory cytokine producing cells. The invention is also directed to methods of treatment of an immune-related disorder in a subject comprising decreasing the amount, the expression, or the activity of leptin in the subject sufficient to treat the immune-related disorder. |
US08969283B2 |
Low odor, hard surface sporicides and chemical decontaminants
A low odor, liquid disinfectant composition comprising multiple components, which, upon mixing, provide an aqueous solution comprising low levels of peracetic acid for use in decontaminating articles and surfaces contaminated with bacteria, viruses, fungi and other chemical and biological contaminants including, but not limited to, spores, such as Clostridium difficile (C. diff), Clostridium sporogenes, and anthrax, mouse parvo virus, and mustard, nerve and other chemical and biological warfare agents. The disinfectant composition is prepared just prior to use by combining two or more separately packaged components, one component which is an acetyl donor comprising TAED or DAMA, and the other component which is a hydrogen peroxide solution. |
US08969278B2 |
Composition with surface modifying properties
The present invention refers to an aqueous composition comprising one or more amphoteric, organic polynitrogen-compounds having at least 3 nitrogen atoms contained in the molecule in the form of an amine and/or amide and one or more types of inorganic nanoparticles, a concentrate comprising said composition and to a method for treating and/or cleaning a surface which uses said composition. |
US08969271B2 |
Polyakylene glycols useful as lubricant additives for groups I-IV hydrocarbon oils
Certain polyalkylene glycols, useful as lubricant additives, are soluble with all four types of hydrocarbon base oils (Groups I-IV) at a wide variety of ratios of oil to polyalkylene glycol and under a variety of conditions. These polyalkylene glycols are prepared by reacting a C8-C20 alcohol and a mixed butylene oxide/propylene oxide feed, wherein the ratio of butylene oxide to propylene oxide ranges from 3:1 to 1:1. The invention provides a means of providing desirable lubricant compositions which may pose fewer environmental problems. |
US08969269B2 |
Lubricating grease composition
A lubricating grease composition for extreme pressure applications requiring extended lubrication intervals comprises a major amount of a lubricating base oil; a lithium complex thickener; and a polar compound selected from the group consisting of a rust inhibitor, a non-ionic surfactant, and mixtures thereof; wherein the concentration of the polar compound in the lubricating grease composition is no more than 0.5 wt. %, based on the total weight of the lubricating grease composition. |
US08969266B2 |
Lubricating composition containing a carboxylic functionalised polymer
The invention provides a lubricating composition comprising an oil of lubricating viscosity and an amine-functionalized additive, wherein the amine-functionalized additive is derived from an amine having at least 3 aromatic groups, at least one —NH2 functional group, and at least 2 secondary or tertiary amino groups. The invention further provides for the additive to have improved thermal and oxidative stability modifying properties. The lubricating composition may include circulating oils, turbine oils, hydraulic fluids, transformer oils and greases as well as others that require good oxidation stability and good rust inhibition properties. |
US08969265B2 |
Lubricating oil compositions
A lubricating oil composition is disclosed which comprises (a) a major amount of an oil of lubricating viscosity; (b) one or more non-halogen-containing oil-soluble titanium complexes comprising at least one ligand comprising an anion of a carboxylic acid; (c) one or more dispersants; and (d) one or more detergents, wherein the lubricating oil composition is free of any zinc dialkyldithiophosphate. |
US08969264B2 |
Oil or gas treatment fluid containing a chelate or coordination complex that sets
A treatment fluid comprises: a metal oxide, wherein the metal oxide is capable of forming a chelate complex or coordination complex with a ligand, wherein the chelate complex or coordination complex has a setting time of less than 90 minutes at a temperature of 71° F. and a pressure of 1 atmosphere. A method of treating a portion of a subterranean formation comprises: introducing the treatment fluid into the subterranean formation; allowing or causing a chelate complex or coordination complex to form between the metal oxide and a ligand; and allowing or causing the chelate complex or coordination complex to set. |
US08969259B2 |
Bio-based synthetic fluids
A method is provided involving altering the viscosity of bio-derived paraffins to produce a paraffinic fluid, where the altering step includes oligomerizing bio-derived paraffins, unsaturating bio-derived paraffins, chlorinating bio-derived paraffins, or a combination of any two or more thereof; the bio-derived paraffins are produced by hydrodeoxygenating a bio-based feed; the bio-based feed comprises bio-derived fatty acids, fatty acid esters, or a combination thereof; the bio-derived paraffins comprise n-paraffins; and the n-paraffins have a biodegradability of at least 40% after about 23 days of exposure to microorganisms. Also provided are methods of protecting a substance by applying a paraffinic fluid and a method of producing an orifice in a substrate by at least injecting a paraffinic fluid into the substrate. |
US08969258B2 |
Methods of localizing nucleic acids to arrays
Methods are disclosed relating to localizing nucleic acids to arrays such as silane-free arrays, and of sequencing the nucleic acids localized thereby. |
US08969256B2 |
Solution microarrays and uses thereof
The present invention relates to solution microarrays. In particular, the present invention relates to an aqueous 2-phase system for solution microarrays and uses thereof. The present invention further relates to systems and methods for performing assays within the solution microarrays (e.g., diagnostic assays). |
US08969255B2 |
Compound arrays for sample profiling
The invention provides arrays of compound for use in profiling samples. The arrays include compounds bind to components of the samples at relatively low affinities. The avidity of compounds binding to components of the samples can be increased by forming arrays such that multivalent components of the samples (e.g., antibodies or cells) can bind to more than one molecule of a compound at the same time. When a sample is applied to an array under such conditions, the compounds of the array bind to component(s) of the sample with significantly different avidities generating a profile characteristic of the sample. |
US08969248B2 |
5-iodotriazole derivatives
The present invention relates to novel 5-iodotriazole derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators. |
US08969247B2 |
Method for controlling aquatic weeds
The invention relates to a method for controlling aquatic weeds by applying a herbicidally effective amount of at least one inhibitor of p-hydroxyphenylpyruvate dioxygenase (HPPD) or an agriculturally acceptable salt, ester or amide thereof to aquatic weeds and/or their aqueous habitat containing seeds or other propagating organs of said aquatic weeds. |
US08969246B2 |
Pesticidal mixtures
Pesticidal mixtures comprising, as active components, 1) an anthranilamid compound of the formula I wherein the variables are defined according to the description, and 2) at least one fungicidal compound II selected from the following groups: strobilurins, carboxamides, heterocylic compounds and other active compounds according to the description, in a synergistically effective amount, methods for controlling pests, and harmful fungi, methods of protecting plants from attack or infestation by insects, acarids or nematodes, methods for treating, controlling, preventing or protecting an animal against infestation or infection by parasites, compositions containing these mixtures, and methods for their preparation. |
US08969244B2 |
Metallized thermal dye image receiver elements and imaging
A thermal dye image receiver element has a substrate comprising a voided compliant layer and metalized layer. Disposed on the metalized layer is an opacifying layer that includes an opacifying agent and a dye receiving layer. This thermal dye image receiver element can be a duplex element with image receiving layers on both sides of the substrate, and it can be used in association with a thermal donor element to provide a thermal image on either or opposing sides of the receiver element. The metalized layer provides increased specular reflectance under resulting thermal dye images. |
US08969243B2 |
Hybrid topcoat formulations for paper products
Hybrid topcoat formulations comprising a water soluble polymer and a water dispersible polymer provide improved adhesion to underlying surfaces. Paper products coated with these formulations, such as thermal paper, achieve high stain resistance and improved adhesion of UV cured silicone release layers. |
US08969231B2 |
Fischer-Tropsch catalysts
A method of producing an alumina-supported cobalt catalyst for use in a Fischer-Tropsch synthesis reaction, which comprises: calcining an initial γ-alumina support material at a temperature to produce a modified alumina support material; impregnating the modified alumina support material with a source of cobalt; calcining the impregnated support material, activating the catalyst with a reducing gas, steam treating the activated catalyst, and activating the steam treated catalyst with a reducing gas. |
US08969230B2 |
Cyclic process for absorption and regeneration of acidic gases
The present invention describes the process of preparing ceramics for the absorption of ACIDIC gases, which worsen the greenhouse effect, that are released in combustion systems, or that are present in closed environments. In relation to carbon dioxide, principal target of the present invention, the process of absorption, transport, processing and transformation of the gas into other products is described. The process uses ceramic materials prepared through the solid mixture of one or more metallic oxides, with one or more binding agents and an expanding agent. The product generated can be processed and the absorbent system regenerated. The carbon dioxide obtained in the processing can be used as analytic or commercial carbonic gas, various carbamates and ammonium carbonate. |
US08969229B2 |
Gas separation adsorbents and manufacturing method
The present invention generally relates to high rate adsorbents and a method for their manufacture involving the steps of component mixing, extrusion, spheronization and calcination. The component mixing can involve both dry mixing in addition to wet mixing of an adsorbent with a binder, if required, and a fluid such as water. The paste so formed from the mixing stage is extruded to produce pellets which are optionally converted to beads by spheronization using in one embodiment, a marumerizer. The product is harvested and calcined to set any binder or binders used and/or burn out any additives or processing aids. This basic manufacturing scheme can be augmented by extra processing steps including ion exchange and activation to alter the composition of the adsorbents, as required. |
US08969225B2 |
Incorporation of nanoparticles in composite fibers
A method includes a providing a molten glass fiber core and disposing a plurality of nanoparticles that include a transition metal oxide on the molten glass fiber core at or above the softening temperature of the glass fiber core, thereby forming a nanoparticle-laden glass fiber. The plurality of nanoparticles are embedded at the surface of said glass fiber core. A method includes providing a mixture of molten glass and a plurality of nanoparticles. The plurality of nanoparticles include a transition metal. The method further includes forming nanoparticle-laden glass fibers, in which the plurality of nanoparticles are embedded throughout the glass fibers. |
US08969223B2 |
Woven preform, composite, and method of making thereof
A three dimensional woven preform, a fiber reinforced composite incorporating the preform, and methods of making thereof are disclosed. The woven preform includes one or more layers of a warp steered fabric. A portion of the warp steered fabric is compressed into a mold to form an upstanding leg. The preform includes the upstanding leg and a joggle in a body portion. The body portion and upstanding leg are integrally woven so there is continuous fiber across the preform. A portion of the warp steered fabric includes stretch broken carbon fibers in the warp direction, and another portion includes conventional carbon fibers. The warp steered fabric can be woven on a loom equipped with a differential take-up mechanism. The warp steered fabric can be a single or multilayer fabric. The preform or the composite can be a portion of an aircraft window frame. |
US08969219B2 |
UV-curable inorganic-organic hybrid resin and method for preparation thereof
The present invention relates to a method for preparation of an ultraviolet (UV)-curable inorganic-organic hybrid resin containing about or less than 4% volatiles and less than 30% organic residues. The UV-curable inorganic-organic hybrid resin obtained according to this method can be UV-cured within a markedly very short time and enables, upon curing, the formation of a transparent shrink-and crack-free glass-like product having high optical quality, high thermal stability and good bonding properties. In view of these properties, this hybrid resin can be used in various applications such as electro-optic, microelectronic, stereolithography and biophotonic applications. |
US08969217B2 |
Methods of treating semiconductor substrates, methods of forming openings during semiconductor fabrication, and methods of removing particles from over semiconductor substrates
Some embodiments include methods of treating semiconductor substrates. The substrates may be exposed to one or more conditions that vary continuously. The conditions may include temperature gradients, concentration gradients of one or more compositions that quench etchant, pH gradients to assist in removing particles, and/or concentration gradients of one or more compositions that assist in removing particles. The continuously varying conditions may be imparted by placing the semiconductor substrates in a bath of flowing rinsing solution, with the bath having at least two feed lines that provide the rinsing solution therein. One of the feed lines may be at a first condition, and the other may be at a second condition that is different from the first condition. The relative amount of rinsing solution provided to the bath by each feed line may be varied to continuously vary the condition within the bath. |
US08969216B2 |
Method for single side texturing
A method for single side texturing of a crystalline semiconductor substrate (10) comprises: providing a substrate (10), for example a semiconductor substrate, comprising a first surface (12) and a second surface (14) opposite to one another with respect to the substrate (10); providing a masking layer (21) with a random pattern on the first surface (12) of the substrate (10); and etching the substrate (10) in a polishing solution, thereby texturing the first surface (12) of the substrate (10) and polishing the second surface (14) in a single wet etching step. |
US08969211B2 |
Method and apparatus for plasma processing
The present invention provides a plasma processing method that uses a plasma processing apparatus including a plasma processing chamber in which a sample is plasma processed, a first radio-frequency power supply that supplies a first radio-frequency power for generating plasma, and a second radio-frequency power supply that supplies a second radio-frequency power to a sample stage on which the sample is mounted, wherein the plasma processing method includes the steps of modulating the first radio-frequency power by a first pulse; and controlling a plasma dissociation state to create a desired dissociation state by gradually controlling a duty ratio of the first pulse as a plasma processing time elapses. |
US08969210B2 |
Plasma etching apparatus, plasma etching method, and semiconductor device manufacturing method
There is provided a plasma etching apparatus provided for performing an etching in a desirable shape. The plasma etching apparatus includes a processing chamber 12 for performing a plasma process on a target substrate W; a gas supply unit 13 for supplying a plasma processing gas into the processing chamber 12; a supporting table positioned within the processing chamber 12 and configured to support the target substrate thereon; a microwave generator 15 for generating a microwave for plasma excitation; a plasma generation unit for generating plasma within the processing chamber 12 by using the generated microwave; a pressure control unit for controlling a pressure within the processing chamber 12; a bias power supply unit for supplying AC bias power to the supporting table 14; and a control unit for controlling the AC bias power by alternately repeating supply and stop of the AC bias power. |
US08969209B2 |
Method for removing oxide
A method for removing oxide is described. A substrate is provided, including an exposed portion whereon a native oxide layer has been formed. A removing oxide process is performed to the substrate using nitrogen trifluoride (NF3) and ammonia (NH3) as a reactant gas, wherein the volumetric flow rate of NF3 is greater than that of NH3. |
US08969208B2 |
Method to form convex structure on surface of semiconductor material
A process to form a lens on a semiconductor material is disclosed. The process includes steps of: forming double layers of an intermediate layer on the semiconductor material and a mask layer made of hard-baked photoresist on the semiconductor substrate; the first transcribing the convex shape of the mask layer on the intermediate layer; and the second scribing the convex shape of the intermediate layer on the semiconductor material. |
US08969207B2 |
Methods of forming a masking layer for patterning underlying structures
One illustrative method disclosed herein includes forming a patterned hard mask layer comprised of a plurality of discrete openings above a structure, wherein the patterned hard mask layer is comprised of a plurality of intersecting line-type features, forming a patterned etch mask above the patterned hard mask layer that exposes at least one, but not all, of the plurality of discrete openings, and performing at least one etching process through the patterned etch mask and the at least one exposed opening in the patterned hard mask layer to define an opening in the structure. |
US08969201B2 |
Contact structure of semiconductor device priority claim
The invention relates to a contact structure of a semiconductor device. An exemplary structure for a contact structure for a semiconductor device comprises a substrate comprising a major surface and a trench below the major surface; a strained material filling the trench, wherein a lattice constant of the strained material is different from a lattice constant of the substrate; an inter-layer dielectric (ILD) layer having an opening over the strained material, wherein the opening comprises dielectric sidewalls and a strained material bottom; a semiconductor layer on the sidewalls and bottom of the opening; a dielectric layer on the semiconductor layer; and a metal layer filling an opening of the dielectric layer. |
US08969193B2 |
Method of producing a semiconductor device having an interconnect through the substrate
A semiconductor substrate (1) is provided on a main surface (14) with an intermetal dielectric (4) including metal planes (5) and on an opposite rear surface (15) with an insulation layer (2) and an electrically conductive connection pad (7). An etch stop layer (6) is applied on the intermetal dielectric to prevent a removal of the intermetal dielectric above the metal planes during subsequent method steps. An opening (9) having a side wall (3) and a bottom (13) is formed from the main surface through the substrate above the connection pad. A side wall spacer (10) is formed on the side wall by a production and subsequent partial removal of a dielectric layer (11). The insulation layer is removed from the bottom to uncover an area of the connection pad. A metal layer is applied in the opening and is provided for an interconnect through the substrate. |
US08969190B2 |
Methods of forming a layer of silicon on a layer of silicon/germanium
Disclosed herein are various methods of forming a layer of silicon on a layer of silicon/germanium. In one example, a method disclosed herein includes forming a silicon/germanium material on a semiconducting substrate, after forming the silicon/germanium material, performing a heating process to raise a temperature of the substrate to a desired silicon formation temperature while flowing a silicon-containing precursor and a chlorine-containing precursor into the deposition chamber during the heating process, and, after the temperature of the substrate reaches the desired silicon formation temperature, forming a layer of silicon on the silicon/germanium material. |
US08969189B2 |
Contact structure employing a self-aligned gate cap
After formation of a replacement gate structure, a template dielectric layer employed to pattern the replacement gate structure is removed. After deposition of a dielectric liner, a first dielectric material layer is deposited by an anisotropic deposition and an isotropic etchback. A second dielectric material layer is deposited and planarized employing the first dielectric material portion as a stopping structure. The first dielectric material portion is removed selective to the second dielectric material layer, and is replaced with gate cap dielectric material portion including at least one dielectric material different from the materials of the dielectric material layers. A contact via hole extending to a source/drain region is formed employing the gate cap dielectric material portion as an etch stop structure. A contact via structure is spaced from the replacement gate structure at least by remaining portions of the gate cap dielectric material portion. |
US08969187B2 |
Self-aligned contacts
A method of forming a gate structure with a self-aligned contact is provided and includes sequentially depositing a sacrificial layer and a secondary layer onto poly-Si disposed at a location of the gate structure, encapsulating the sacrificial layer, the secondary layer and the poly-Si, removing the sacrificial layer through openings formed in the secondary layer and forming silicide within at least the space formally occupied by the sacrificial layer. |
US08969185B2 |
Manufacturing apparatus and manufacturing method for quantum dot material
A manufacturing apparatus and a manufacturing method for a quantum dot material. The manufacturing apparatus adds an optical device capable of generating an interference pattern in an existing epitaxial apparatus, so that a substrate applies an interference pattern on an epitaxial layer while performing epitaxial growth. By means of the interference pattern, a regularly distributed temperature field is formed on the epitaxial layer, so that on the epitaxial layer, an atom aggregation phenomenon is formed at dot positions with higher temperature, but no atoms are aggregated on areas having relatively lower temperature. Therefore, according to the temperature distribution on the surface of the epitaxial layer, positions where quantum dots generate can be controlled manually without introducing defects, thereby achieving a defect-free and long-range ordered quantum dot manufacturing. |
US08969184B2 |
Method for fabricating a porous semiconductor body region
A method for fabricating a porous semiconductor body region, including producing at least one trench in a semiconductor body, starting from a surface of the semiconductor body, producing at least one porous semiconductor body region in the semiconductor body starting from the at least one trench at least along a portion of the side walls of the trench, and filling the trench with a semiconductor material of the semiconductor body. |
US08969180B2 |
Method and system for junction termination in GaN materials using conductivity modulation
A semiconductor structure includes a GaN substrate having a first surface and a second surface opposing the first surface. The GaN substrate is characterized by a first conductivity type and a first dopant concentration. The semiconductor structure also includes a first GaN epitaxial layer of the first conductivity type coupled to the second surface of the GaN substrate and a second GaN epitaxial layer of a second conductivity type coupled to the first GaN epitaxial layer. The second GaN epitaxial layer includes an active device region, a first junction termination region characterized by an implantation region having a first implantation profile, and a second junction termination region characterized by an implantation region having a second implantation profile. |
US08969173B2 |
Method of fabricating electronic component
A method of fabricating an electronic component includes: mounting a device chip on an upper surface of an insulative substrate; forming a sealing portion that seals the device chip; cutting the insulative substrate and the sealing portion; and forming a plated layer covering the sealing portion by barrel plating. |
US08969172B2 |
Method for forming isolation structure
[Problem] To provide a method for forming an isolation structure having a low shrinkage percentage and a low tensile stress.[Means for Solving] A first polysilazane composition containing a porogen is cast on the surface of a substrate to form a coat, and then the coat is fired to form a porous siliceous film having a refractive index of 1.3 or less. Thereafter, the surface of the porous siliceous film is soaked with a second polysilazane composition, and then fired to form an isolation structure of a siliceous film having a refractive index of 1.4 or more. |
US08969171B2 |
Method of making deep trench, and devices formed by the method
A method for forming a semiconductor device includes providing a semiconductor-on-insulator (SOI) structure, and forming at least one hard mask (HM) layer over the SOI structure. The SOI structure includes an insulator layer and a semiconductor layer over the insulator layer. The method further comprises forming a trench inside the at least one HM layer and the semiconductor layer, and depositing a spacer layer in the trench. The spacer layer comprises a bottom surface portion over the bottom surface of the trench, and a side wall portion along the side wall of the trench. The method further comprises etching the bottom surface portion of the spacer layer while the side wall portion of the spacer layer remains, and etching the insulator layer to extend the trench into the insulator layer. |
US08969165B2 |
Self-aligned insulating etchstop layer on a metal contact
A semiconductor device comprising a substrate having a transistor that includes a metal gate structure; a first oxide layer formed over the substrate; a silane layer formed on the first oxide layer; and a non-conductive metal oxide layer grown on the metal gate structure, wherein the silane layer inhibits nucleation and growth of the non-conductive metal oxide layer. |
US08969164B2 |
Semiconductor structure and method for manufacturing the same
A semiconductor structure comprises a substrate, a gate stack, a base area, and a source/drain region, wherein the gate stack is located on the base area, the source/drain region is located in the base area, and the base area is located on the substrate. A supporting isolated structure is provided between the base area and the substrate, wherein part of the supporting structure is connected to the substrate; a cavity is provided between the base area and the substrate, wherein the cavity is composed of the base area, the substrate and the supporting isolated structure. A stressed material layer is provided on both sides of the gate stack, the base area and the supporting isolated structure. Correspondingly, a method is provided for manufacturing such a semiconductor structure, which inhibits the short channel effect, reduces the parasitic capacitance and leakage current, and enhances the steepness of the source/drain region. |
US08969162B2 |
Three-dimensional semiconductor device and method for fabricating the same
Provided is a three-dimensional semiconductor device and method for fabricating the same. The device includes a first electrode structure and a second electrode structure stacked sequentially on a substrate. The first and second electrode structures include stacked first electrodes and stacked second electrodes, respectively. Each of the first and second electrodes includes a horizontal portion parallel with the substrate and an extension portion extending from the horizontal portion along a direction penetrating an upper surface of the substrate. Here, the substrate may be closer to top surfaces of the extension portions of the first electrodes than to the horizontal portion of at least one of the second electrodes. |
US08969161B2 |
Semiconductor device and method for fabricating semiconductor device
A semiconductor device includes: an active region configured over a substrate to include a first conductive-type first deep well and second conductive-type second deep well forming a junction therebetween. A gate electrode extends across the junction and over a portion of first conductive-type first deep well and a portion of the second conductive-type second deep well. A second conductive-type source region is in the first conductive-type first deep well at one side of the gate electrode whereas a second conductive-type drain region is in the second conductive-type second deep well on another side of the gate electrode. A first conductive-type impurity region is in the first conductive-type first deep well surrounding the second conductive-type source region and extending toward the junction so as to partially overlap with the gate electrode and/or partially overlap with the second conductive-type source region. |
US08969154B2 |
Methods for fabricating semiconductor device structures and arrays of vertical transistor devices
A semiconductor device structure is disclosed. The semiconductor device structure includes a mesa extending above a substrate. The mesa has a channel region between a first side and second side of the mesa. A first gate is on a first side of the mesa, the first gate comprising a first gate insulator and a first gate conductor comprising graphene overlying the first gate insulator. The gate conductor may comprise graphene in one or more monolayers. Also disclosed are a method for fabricating the semiconductor device structure; an array of vertical transistor devices, including semiconductor devices having the structure disclosed; and a method for fabricating the array of vertical transistor devices. |
US08969149B2 |
Stacked semiconductor nanowires with tunnel spacers
A structure is provided that includes at least one multilayered stacked semiconductor material structure located on a semiconductor substrate and at least one sacrificial gate material structure straddles a portion of the at least one multilayered stacked semiconductor structure. The at least one multilayered stacked semiconductor material structure includes alternating layers of sacrificial semiconductor material and semiconductor nanowire template material. End segments of each layer of sacrificial semiconductor material are then removed and filled with a dielectric spacer. Source/drain regions are formed from exposed sidewalls of each layer of semiconductor nanowire template material, and thereafter the at least one sacrificial gate material structure and remaining portions of the sacrificial semiconductor material are removed suspending each semiconductor material. A gate structure is formed within the areas previously occupied by the at least one sacrificial gate material structure and remaining portions of the sacrificial semiconductor material. |
US08969148B2 |
Method for producing a transistor structure with superimposed nanowires and with a surrounding gate
The present invention relates to a method for producing a microelectronic device having a channel structure formed from superimposed nanowires, in which a nanowire stack having a constant transverse section is firstly formed, followed by a sacrificial gate and insulating spacers, where source and drain areas are then formed by growth of semiconductor material on areas of the stack which are not protected by the sacrificial gate and the insulating spacers (FIG. 4D). |
US08969145B2 |
Wire-last integration method and structure for III-V nanowire devices
In one aspect, a method of fabricating a nanowire FET device includes the following steps. A layer of III-V semiconductor material is formed on an SOI layer of an SOI wafer. Fins are etched into the III-V material and SOI layer. One or more dummy gates are formed over a portion of the fins that serves as a channel region of the device. A gap filler material is deposited onto the wafer. The dummy gates are removed selective to the gap filler material, forming trenches in the gap filler material. The SOI layer is removed from portions of the fins within the trenches thereby forming suspended nanowire channels in the channel regions of the device. The trenches are filled with at least one gate material to form one or more replacement gates surrounding the nanowire channels in a gate-all-around configuration. |
US08969143B2 |
Semiconductor package and method of manufacturing the same
A light-emitting device package including a lead frame formed of a metal and on which a light-emitting device chip is mounted; and a mold frame coupled to the lead frame by injection molding. The lead frame includes: a mounting portion on which the light-emitting device chip is mounted; and first and second connection portions that are disposed on two sides of the mounting portion in a first direction and connected to the light-emitting device chip by wire bonding, wherein the first connection portion is stepped with respect to the mounting portion, and a stepped amount is less than a material thickness of the lead frame. |
US08969142B2 |
Switching materials comprising mixed nanoscopic particles and carbon nanotubes and methods of making and using the same
An improved switching material for forming a composite article over a substrate is disclosed. A first volume of nanotubes is combined with a second volume of nanoscopic particles in a predefined ration relative to the first volume of nanotubes to form a mixture. This mixture can then be deposited over a substrate as a relatively thick composite article via a spin coating process. The composite article may possess improved switching properties over that of a nanotube-only switching article. A method for forming substantially uniform nanoscopic particles of carbon, which contains one or more allotropes of carbon, is also disclosed. |
US08969141B2 |
Programmable poly fuse using a P-N junction breakdown
According to one exemplary embodiment, a programmable poly fuse includes a P type resistive poly segment forming a P-N junction with an adjacent N type resistive poly segment. The programmable poly fuse further includes a P side silicided poly line contiguous with the P type resistive poly segment and coupled to a P side terminal of the poly fuse. The programmable poly fuse further includes an N side silicided poly line contiguous with the N type resistive poly segment and coupled to an N side terminal of the poly fuse. During a normal operating mode, a voltage less than or equal to approximately 2.5 volts is applied to the N side terminal of the programmable poly fuse. A voltage higher than approximately 3.5 volts is required at the N side terminal of the poly fuse to break down the P-N junction. |
US08969139B2 |
Lead frame array package with flip chip die attach
A small form factor near chip scale package is provided that includes input/output contacts not only along the periphery of the package, but also along the package bottom area. Embodiments provide these additional contacts through use of an array lead frame coupled to under die signal contacts through the use of flip chip bonding techniques. The array lead frame contacts are electrically isolated through the use of a partial sawing process performed during package singulation. |
US08969134B2 |
Laser ablation tape for solder interconnect formation
A tape capable of laser ablation may be used in the formation of microelectronic interconnects, wherein the tape may be attached to bond pads on a microelectronic device and vias may be formed by laser ablation through the tape to expose at least a portion of corresponding bond pads. The microelectronic interconnects may be formed on the bond pads within the vias, such as by solder paste printing and solder reflow. The laser ablation tape can be removed after the formation of the microelectronic interconnects. |
US08969129B2 |
ReRAM cells including TaXSiYN embedded resistors
Provided are resistive random access memory (ReRAM) cells and methods of fabricating thereof. A ReRAM cell includes an embedded resistor and a resistive switching layer connected in series with this resistor. The resistor is configured to prevent over-programming of the cell by limiting electrical currents through the resistive switching layer. Unlike the resistive switching layer, which changes its resistance in order to store data, the embedded resistor maintains a substantially constant resistance during operation of the cell. The embedded resistor is formed from tantalum nitride and silicon nitride. The atomic ratio of tantalum and silicon may be specifically selected to yield resistors with desired densities and resistivities as well as ability to remain amorphous when subjected to various annealing conditions. The embedded resistor may also function as a diffusion barrier layer and prevent migration of components between one of the electrodes and the resistive switching layer. |
US08969125B2 |
Solar cell and method for manufacturing the same
A method for manufacturing a solar cell includes texturing a front surface of a semiconductor substrate having a first conductive type dopant by using a dry etching method, forming an emitter layer by ion-implanting a second conductive type dopant into the front surface of the semiconductor substrate, forming a back passivation film on a back surface of the semiconductor substrate; and forming a first electrode electrically connected to the emitter layer and a second electrode being in partial contact with the back surface of the semiconductor substrate. |
US08969121B2 |
Method for manufacturing solar cell
A method for manufacturing a solar cell according to an embodiment of the present invention includes preparing a semiconductor substrate having a first conductivity type dopant; ion-implanting a pre-amorphization elements into a front surface of the semiconductor substrate to form an amorphous layer; and forming an emitter layer by ion-implanting second conductivity type dopant into the front surface of the semiconductor substrate. The method then further includes heat-treating the layers to activate the second conductivity type dopant. The method further includes forming a back surface field layer at a back surface of the semiconductor substrate by ion-implanting a first conductivity type dopant. |
US08969118B2 |
Integrated carbon nanotube field effect transistor and nanochannel for sequencing
A mechanism is provided for base recognition of an integrated transistor and nanochannel. A target molecule is forced down to a carbon nanotube a single base at a time in the nanochannel by applying a gate voltage to a top electrode, and/or a narrow thickness of the nanochannel. The nanochannel exposes an exposed portion of the carbon nanotube at a bottom wall, and the top electrode is positioned over the exposed portion. The exposed portion of the carbon nanotube is smaller than the distance between bases to only accommodate the single base at a time. The target molecule is stretched by the narrow thickness and by applying a traverse voltage across a length direction of the nanochannel. The target molecule is frictionally restricted by the narrow thickness of the nanochannel to stretch is restrictedly translocates in the length direction. Current is measured to determine an identity of the single base. |
US08969117B2 |
Method for forming a buried p-n junction and articles formed thereby
Methods for forming a buried p-n junction and avalanche photodiodes incorporating same are disclosed. The method includes forming a well in a semiconductor layer, wherein a depth of the well is selected as a function of the desired shape of the p-n junction in the edge region of the avalanche photodiode. A diffusion mask is then formed on the semiconductor layer, wherein the diffusion mask includes at least two openings per APD formed, wherein one opening is a diffusion window and the other is a diffusion sink. The depth of the p-n junction in the active region of the APD is based, in part, on an attribute of the diffusion mask relating to the diffusion sink. |
US08969115B2 |
Transparent conductive electrode stack containing carbon-containing material
A transparent conductive electrode stack containing a work function adjusted carbon-containing material is provided. Specifically, the transparent conductive electrode stack includes a layer of a carbon-containing material and a layer of a work function modifying material. The presence of the work function modifying material in the transparent conductive electrode stack shifts the work function of the layer of carbon-containing material to a higher value for better hole injection into the OLED device as compared to a transparent conductive electrode that includes only a layer of carbon-containing material and no work function modifying material. |
US08969113B2 |
Optical device structure using GaN substrates and growth structures for laser applications
Optical devices having a structured active region configured for selected wavelengths of light emissions are disclosed. |
US08969112B2 |
Optoelectronic device with light directing arrangement and method of forming the arrangement
An optoelectronic device comprises a body of an indirect bandgap semiconductor material having a surface and a photon active region on one side of the surface. A light directing arrangement is formed integrally with the body on an opposite side of the surface. |
US08969111B2 |
Method for manufacturing display device
An IZO layer (113) is formed on an a-ITO layer (112), and resist patterns (202R, 202G) having different film thicknesses are formed in at least sub-pixels (71R, 71G). The a-ITO layer (112) and the IZO layer (113) are etched by utilizing (i) a reduction in thickness of the resist patterns (202R, 202G) by ashing and (ii) a change in etching tolerance due to transformation from the a-ITO layer (112) into a p-ITO layer (114). |
US08969110B2 |
Method of manufacturing organic light-emitting display apparatus
A method of manufacturing an organic light-emitting display apparatus includes: providing an organic light emission part on a substrate; providing a first inorganic layer including a first low temperature viscosity transition (“LVT”) inorganic material on the substrate to cover the organic light emission part; and adding fluoride into the first inorganic layer using a fluorine group material such that the first inorganic layer is converted into a second inorganic layer comprising a second low temperature viscosity transition inorganic material. |
US08969108B2 |
Light emitting diode and forming method thereof
A light emitting diode (LED) and a forming method thereof are provided. The method for forming the LED includes: providing a semiconductor substrate (20) and a sapphire substrate (30) respectively, wherein a first bonding layer (21) is formed on the silicon substrate (20), and a sacrificial layer (32), an LED die (33) and a second bonding layer (35) are formed in turn on the sapphire substrate (30); bonding the first bonding layer (21) and the second bonding layer (35); removing the sacrificial layer (32) and lifting off the sapphire substrate (30). The method increases the effective lighting area of the LED, improves heat radiation, and enhances lighting efficiency. |
US08969107B2 |
Method of manufacturing a nano-rod and method of manufacturing a display substrate
A method of manufacturing a nano-rod and a method of manufacturing a display substrate in which a seed including a metal oxide is formed. A nano-rod is formed by reacting the seed with a metal precursor in an organic solvent. Therefore, the nano-rod may be easily formed, and a manufacturing reliability of the nano-rod and a display substrate using the nano-rod may be improved. |
US08969105B2 |
Forming a device having a curved piezoelectric membrane
Processes for forming an actuator having a curved piezoelectric membrane are disclosed. The processes utilize a profile-transferring substrate having a curved surface surrounded by a planar surface to form the curved piezoelectric membrane. The piezoelectric material used for the piezoelectric actuator is deposited on at least the curved surface of the profile-transferring substrate before the profile-transferring substrate is removed from the underside of the curved piezoelectric membrane. The resulting curved piezoelectric membrane includes grain structures that are columnar and aligned, and all or substantially all of the columnar grains are locally perpendicular to the curved surface of the piezoelectric membrane. |
US08969103B2 |
Method for manufacturing silicon carbide substrate and method for manufacturing semiconductor device
A silicon carbide substrate is made of silicon carbide. In the silicon carbide substrate, a normal line of one main surface of the silicon carbide substrate and a normal line of a {03-38} plane form an angle of 0.5° or smaller in an orthogonal projection to a plane including a <01-10> direction and a <0001> direction. In this way, there can be provided the silicon carbide substrate allowing for both improvement of channel mobility of a semiconductor device and stable characteristics thereof. |
US08969101B1 |
Three axis magnetic sensor device and method using flex cables
A method and structure for a three-axis magnetic field sensing device. An IC layer having first bond pads and second bond pads can be formed overlying a substrate/SOI member with a first, second, and third magnetic sensing element coupled the IC layer. One or more conductive cables can be formed to couple the first and second bond pads of the IC layer. A portion of the substrate member and IC layer can be removed to separate the first and second magnetic sensing elements on a first substrate member from the third sensing element on a second substrate member, and the third sensing element can be coupled to the side-wall of the first substrate member. |
US08969100B2 |
Method for detecting afferent lymph vessel inflow regions and method for identifying specific cells
Regions where metastatic cancer cells can exist are detected with high accuracy in a sentinel lymph node. Quantum dots are injected into the vicinity of a cancer in a living body, thereby identifying the location of the sentinel lymph node by means of fluorescence. Subsequently, the sentinel lymph node is extracted. With respect to the sentinel lymph node extracted with quantum dots injected, structural analysis is conducted by means of precision fluorescence measurement which uses a confocal fluorescence microscope for monomolecular observation. Specifically, the fluorescence intensity is measured with respect to each of multiple areas in the sentinel lymph nodes, and out of the multiple areas measured, one or more areas are detected as afferent lymph vessel inflow regions in descending order of fluorescence intensity. |
US08969098B2 |
Methods and systems providing reagent mixing
Disclosed are methods and systems adapted to provide mixing of a liquid reagent in an automated clinical analyzer. The methods include aspirating an air separator (e.g., an air slug) into the interior of a probe. A relatively small volume of reagent liquid is also aspirated into the probe adjacent to the air separator; the volume of liquid reagent being entirely contained within the probe. The volume of liquid reagent may be repeatedly aspirated and dispensed at a relatively high frequency to accomplish reagent mixing in the reagent container. Improved sample and reagent mixing may be promoted using a similar method. Systems carrying out the methods are provided, as are other aspects. |
US08969097B2 |
Analyte detection devices and methods with hematocrit-volume correction and feedback control
Disclosed are devices, arrangements and methods for quantifying the concentration of an analyte present in bodily fluid, including: an assay pad having at least one chemical reagent capable of producing a detectable signal in the form of a reaction spot upon reaction with the analyte; a light source; a detector array; a processor; and a memory in communication with the processor, the memory comprising: (a) at least one value indicative of one or more of: (i) the level of hematocrit contained in the sample; (ii) the volume of the sample applied to the assay pad; or (iii) imperfections present in the reaction spot; and (b) at least one algorithm for calculating the concentration of the analyte contained in the sample. |
US08969095B1 |
Method and system for explosive detection
The present invention is directed to methods and systems for detecting the presence of explosive elements. A sample element may be used to swipe an object for a test sample. The sample element may be positioned in a sample holder of a testing device having a heater. The heater may be programmed to heat the sample element and sample in a controlled manner through two or three temperature increases from approximately 35 degrees to 165 degrees centigrade in approximately 40 seconds. Prior to each temperature increase a first, second and third reagent fluid is applied to the sample holder, and during the temperature rise the sample holder is observed for the presence of various explosive elements by detecting colors as compared to a color chart. The color observations may be based on time and temperature variations using a testing device. |
US08969093B1 |
Calibration method and device for remote location testing instruments
Constant calibration methods and apparatuses for analytical devices that are located in remote positions in order to allow for reliable and automated measurements of various contaminants within water or other liquid samples. The proposed calibration systems allow for certain methods to measure total amounts of certain trihalomethane and haloacetic acid contaminants, at least, in drinking water samples from such remote locations, through the utilization of a standard addition introduction of known concentrations of such contaminant compounds within target samples, followed by separation through a capillary membrane sampling device and measurement of such different contaminants via flow injection analysis (FIA). In such a manner, the on-line, remote system provides the necessary reliability for a water utility or like entity on which to base any further needed water treatment activities without having to perform such measurements in a distinct lab setting. |
US08969092B2 |
Gel particle measurement reagent and measurement method using same
Provided is a gel particle measurement reagent effective in quickly measuring a time point of initiation of production of gel particles. A gel particle measurement reagent R is a gel particle measurement reagent to be used to be agitated continuously with a sample S containing a target substance St as a measuring object to turn the target substance St into gel particles, including: a reagent base material 1 that undergoes a gelation reaction with the target substance St; and a biologically inactive particle formation accelerating factor 2 that is added to the reagent base material, has solubility in the sample S and dissolves therein at a concentration of 0.002 to 1%, and accelerates production of gel particles G whose particle sizes are centered in a predetermined range. |
US08969091B2 |
Study of polymer molecules and conformations with a nanopore
The invention features methods for evaluating the conformation of a polymer, for example, for determining the conformational distribution of a plurality of polymers and to detect binding or denaturation events. The methods employ a nanopore which the polymer, e.g., a nucleic acid, traverses. As the polymer traverses the nanopore, measurements of transport properties of the nanopore yield data on the conformation of the polymer. |
US08969089B2 |
Analysis of amino acids in body fluid by liquid chromatography-mass spectrometry
This disclosure provides methods for quantifying individual amino acids in various bodily fluids obtained from a human patient. Also provided are reference ranges for normal amino acid levels in the various bodily fluids (e.g., blood plasma, urine, cerebrospinal fluid, and saliva) and for various age groups (e.g., neonates, infants, children, and adults). |
US08969088B2 |
Substrate mimicking intercellular lipids in stratum corneum and method of evaluating skin roughening using the same
A substrate mimicking intercellular lipids in stratum corneum consisting of a substrate and a lipid membrane formed on the substrate, wherein the lipid membrane is formed from ceramide, palmitic acid and cholesterol, and the ceramide, palmitic acid and cholesterol are present at a mass ratio of 20-70%:10-60%:20-40% (ceramide:palmitic acid:cholesterol). |
US08969087B2 |
Method of pre-treatment and staining of a biological sample and device for support of a biological sample and methods of using such device
There is disclosed a method of pre-treatment and staining, according to a protocol, of a biological sample disposed upon the surface of a carrier, the method comprising the step of recording at least one parameter relating to at least one protocol step in a non-volatile memory located either upon or within the carrier or a device incorporating the carrier. Also disclosed is a device comprising: a non-volatile memory; a surface of the device adapted to carry a biological sample; and communications means electrically coupled to the memory for enabling data transmission to or from an external apparatus. Also disclosed is a method of controlling processing of a biological sample disposed upon a carrier, comprising: providing, upon or within the carrier or an apparatus holding the carrier, a non-volatile memory having information relating to sample processing priority or protocol; reading the information; and scheduling the processing based upon the information. |
US08969086B2 |
Enhanced scheduling sample processing system and methods of biological slide processing
A sample processing system 101 that may be automated and methods are disclosed where sample(s) 198 are arranged on a carrier element 197 and a process operation control system 171 automatically processes the sample(s) perhaps robotically according to an desired aggregation of event dictated by an input 173. Alteration of an initial aggregated event topology may be accepted while the system is processing an initial aggregation and varied-parameter robotic control simulation functionalities 606 may be accomplished to determine an enhanced sequence for processing. Suggested operator actions may be displayed that might further enhance the scheduling of the altered aggregated event topology together with an automatic operator need prompt 608 that may inform an operator of a need for a particular action in order to accomplish the desired tasks. Reversibility to proposed changes may be made available so that an operator may avoid having to activate proposed changes if they cause a processing result that is not acceptable. |
US08969085B2 |
Portable nanoparticle based assay for rapid detection of food antioxidants (NanoCerac)
Methods and assay for the portable colorimetric detection of an antioxidant in a food sample. The method includes the steps of providing a colorimetric reagent, the reagent including a plurality of ceria nanoparticles immobilized to a support, contacting the colorimetric reagent with the food sample, and detecting an optical property of the colorimetric reagent, where a change in the optical property of the colorimetric reagent is associated with the presence of antioxidant in the food sample. The change in the optical property of the colorimetric reagent is dependent upon the concentration of the antioxidant in the food sample. |
US08969084B2 |
Method for detecting sweet odor from air conditioner, reproducing sweet odor and preparing corresponding sweet odor composition
A method that identifies the compounds contributing to a sweet odor from an air conditioner, reproduces the sweet odor, and prepares a corresponding sweet odor composition. Through the analysis method of the present invention, the compounds contributing to the sweet odor from an air conditioner are identified and quantified. The sweet odor is reproduced from a combination of the compounds identified by the analysis method of the present invention. The reproduced sweet odor provides significant data required for development of an apparatus and a method for removing specific odor. |
US08969083B2 |
Method for detecting fish-like odor from air conditioner, reproducing fish-like odor and preparing corresponding fish-like odor composition
A method that identifies the compounds contributing to a fish-like odor from an air conditioner and artificially reproduces the fish-like odor, and prepares a corresponding fish-like odor composition. Through the analysis method of the present invention, the compounds contributing to the fish-like odor from an air conditioner are identified and quantified. The fish-like odor is reproduced from a combination of the compounds identified by the analysis method of the present invention. The reproduced fish-like odor provides significant data required for development of an apparatus and a method for removing specific odor. |
US08969082B2 |
Expression of surrogate light chains
The present invention concerns surrogate light chain (SURROBODY™) constructs comprising surrogate light chain sequences with heterologous signal sequences. |
US08969080B2 |
Remedy for the treatment of cardio-vascular diseases or disorders
Disclosed is the use of inhibitors of β-catenin expression or activity or modulators downregulating β-catenin expression or activity for the treatment of cardiovascular diseases or disorders and their use in the treatment of cardiovascular diseases and disorders, such as heart failure syndrome. The use of those agents resulted in particular in cardiomyocyte differentiation of endogenous cardiac stem cells. |
US08969079B2 |
Method for inducing human blood-born hematospheres through aggregate culture and expanding blood adult stem cells and progenitor cells, and stem cell prepared by the same
The present invention relates to a technique of using monocytic blood cells to effectively culture and proliferate blood adult stem cells and progenitor cells that only exist in small quantities to effectively obtain large quantities of stem cells. According to the present invention, the limitation of being able to derive only small quantities of stem cells from blood can be overcome, and the pluripotency of stem cells can easily be obtained. |
US08969077B2 |
Neuronal specific targeting of caveolin expression to restore synaptic signaling and improve cognitive function in the neurodegenerative brain and motor function in spinal cord
The invention provides an expression system for producing Caveolin-1 in neuronal cells or neural stem cells comprising a neuron-specific regulatory element and a nucleic acid sequence encoding Caveolin-1. |
US08969074B2 |
Electromagnetic bioaccelerator
The present invention relates to an electromagnetic bioaccelerator for obtaining biomass by simulating environmental marine conditions, comprising at least the following elements: octagonal biomass converters (1), seawater reserve tanks (3), particle filters (4), UV light filters (5), feedback and mixture tanks (6), pressurization feed tanks (8), manometers (9), pressure controllers (10), buffer tanks (11), expansion tanks with a safety valve (12), heat exchangers (13), temperature control thermostats (14), recycled water feedback tanks (15), reinjection pumps (16), centrifuges for separating the biomass from the water (17), desuperheaters (18); control panels (25), recirculation pumps (26), densimeters (27), biomass mechanical extraction systems by means of centrifugation (32) and biomass accumulation tanks (33). |
US08969072B2 |
Method for automated unloading of a microbial detection apparatus
The present invention is directed to a method and automated unloading means for unloading a container from an apparatus. The apparatus of the present invention may include a means for automated loading, a means for automated transfer and/or a means for automated unloading of a container (e.g., a specimen container). In one embodiment, the apparatus can be an automated detection apparatus for rapid non-invasive detection of a microbial agent in a test sample. The detection system also including a heated enclosure, a holding means or rack, and/or a detection unit for monitoring and/or interrogating the specimen container to detect whether the container is positive for the presence of a microbial agent. In other embodiment, the automated instrument may include one or more, bar code readers, scanners, cameras, and/or weighing stations to aid in scanning, reading, imaging and weighing of specimen containers within the system. |
US08969070B2 |
Thin-film layered centrifuge device and analysis method using the same
Disclosed herein is a thin-film layered centrifuge device and an analysis method using the same. One example of an embodiment of the present invention is a thin film layered centrifuge device where a device, such as a lab on a chip, a protein chip and a DNA chip, for diagnosing and detecting a small amount of material in a fluid is integrated into a rotatable thin-film layered body, and to an analysis method using the thin-film layered centrifuge device. |
US08969069B2 |
Glycated protein measurement sensor and portable glycated protein measurement apparatus including same
Disclosed are a glycated protein measurement sensor and a portable glycated protein measurement apparatus. The glycated protein measurement sensor includes: a sensing film (300) formed on a predetermined base material (100); and first and second unit sensors (10′, 10″) including a positive (+) electrode (400) and a negative (−) electrode (500) disposed facing each other at a predetermined distance on both ends of the sensing film (300). A ligand composition (600′) including an aromatic boron acid combined with a first target material (700) as an effective component is disposed on the first sensing film (300) of the first unit sensor (10′). Also, a receptor (600″) combined with the first or second target material (700) is disposed on the second sensing film (300) of the second unit sensor (10″). Here, the first target material (700) is a glycated protein (700′), and the second target material (700) is a protein (700″). |
US08969067B2 |
Process for growing biomass by modulating supply of gas to reaction zone
There is provided a process of growing a phototrophic biomass in a reaction zone. Gaseous exhaust material is produced with a gaseous exhaust material producing process, wherein the gaseous exhaust material includes carbon dioxide. A discharge of the gaseous exhaust material is supplied to the reaction zone and is modulated. A bypass gaseous exhaust material, being supplied to another unit operation, is also modulated. |
US08969063B2 |
Herpes simplex viruses and methods of viral replication
A herpes simplex virus is disclosed in which the herpes simplex virus genome comprises a nucleic acid sequence encoding an ING4 polypeptide. |
US08969061B2 |
Compositions, methods and related uses for cleaving modified DNA
Compositions, methods and a kit are described relating to a novel family of enzymes which preferentially bind to a hydroxymethylated cytosine or a glucosylated hydroxymethylated cytosine and cleave double-stranded DNA at a defined distance 3′ of the recognition site to produce a cleavage fragment with a 1-3 base overhang. |
US08969059B2 |
Nucleic acid sample preparation
The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples. |
US08969054B2 |
Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors
The invention provides a non-naturally occurring microbial biocatalyst including a microbial organism having a 4-hydroxybutanoic acid (4-HB) biosynthetic pathway having at least one exogenous nucleic acid encoding 4-hydroxybutanoate dehydrogenase, succinyl-CoA synthetase, CoA-dependent succinic semialdehyde dehydrogenase, or α-ketoglutarate decarboxylase, wherein the exogenous nucleic acid is expressed in sufficient amounts to produce monomeric 4-hydroxybutanoic acid (4-HB). Also provided is a non-naturally occurring microbial biocatalyst including a microbial organism having 4-hydroxybutanoic acid (4-HB) and 1,4-butanediol (BDO) biosynthetic pathways, the pathways include at least one exogenous nucleic acid encoding 4-hydroxybutanoate dehydrogenase, succinyl-CoA synthetase, CoA-dependent succinic semialdehyde dehydrogenase, 4-hydroxybutyrate:CoA transferase, 4-butyrate kinase, phosphotransbutyrylase, α-ketoglutarate decarboxylase, aldehyde dehydrogenase, alcohol dehydrogenase or an aldehyde/alcohol dehydrogenase, wherein the exogenous nucleic acid is expressed in sufficient amounts to produce 1,4-butanediol (BDO). Additionally provided are methods for the production of 4-HB and BDO. |
US08969053B2 |
Mutant YqhD enzyme for the production of a biochemical by fermentation
The present invention concerns a method for the production of a biochemical selected among acetol and 1,2-propanediol, 1,3-propanediol, ethylene glycol and 1,4-butanediol comprising culturing a microorganism modified for an improved production of the biochemical selected among acetol and 1,2-propanediol, 1,3-propanediol, ethylene glycol and 1,4-butanediol in an appropriate culture medium and recovery of the desired biochemical which may be further purified wherein the microorganism expresses a YqhD enzyme which catalytic efficiency toward NADPH is increased.The present invention also relates to a mutant YqhD enzyme comprising at least one amino acid residue in the protein sequence of the parent enzyme replaced by a different amino acid residue at the same position wherein the mutant enzyme has retained more than 50% of the YqhD activity of the parent enzyme and the catalytic efficiency toward NADPH of the mutant YqhD is increased as compared with the catalytic efficiency toward NADPH of the parent enzyme. |
US08969049B2 |
Yarrowia diacylglycerol acyltransferase promoter regions for gene expression in yeast
Promoter regions associated with the Yarrowia lipolytica diacylglycerol acyltransferase 2 (dgat2) gene are disclosed and have been found to be particularly effective for the expression of heterologous genes in yeast. These promoter regions will be useful for driving high-level expression of genes involved in the production of omega-3 and omega-6 fatty acids. |
US08969046B2 |
Methods for detecting epigenetic modifications
A method of detecting a predisposition to, or the incidence of, cancer in a sample comprises detecting an epigenetic change in at least one gene selected from an NDRG4/NDRG2 subfamily gene, GATA4, OSMR, GATA5, SFRP1, ADAM23, JPH3, SFRP2, APC, MGMT, TFPI2, BNIP3, FOXE1, SYNE1, S0X17, PHACTR3 and JAM3, wherein detection of the epigenetic change is indicative of a predisposition to, or the incidence of, cancer. Also described are pharmacogenetic methods for determining suitable treatment regimens for cancer and methods for treating cancer patients, based around selection of the patients according to the methods of the invention. The present invention is also concerned with improved methods of collecting, processing and analyzing samples, in particular body fluid samples. These methods may be useful in diagnosing, staging or otherwise characterizing various diseases. The invention also relates to methods for identifying, diagnosing, staging or otherwise characterizing cancers, in particular gastrointestinal cancers such as colorectal cancers, gastric cancers and oesophageal cancers. The methods of the invention relate, inter alia, to isolating and analyzing the human DNA component from faecal samples and blood-based samples. |
US08969041B2 |
Large scale and stable production of human FVIII in the human cell line Sk-Hep-1
The present invention refers to: 1) the method for the production of recombinant FVIII in human Sk-Hep-1 cells, comprising von Willebrand Factor (vWF) and 2) the population of human cells transduced with a vector encoding the clotting protein (FVIII). The technical object of the present patent application is intended for the cultivation of human cells in suspension and in adhesion and isolation of the culture medium containing the desired protein. The object of the invention is to provide a safer product (free of potential human viruses), that is cheaper and more stable, by means of a method that provides sufficient amounts and on industrial scale to meet the National demand. |
US08969033B2 |
Alteration and modulation of protein activity by varying post-translational modification
Embodiments of the invention include methods of altering the enzymatic activity or solubility of an extremophilic enzyme or post-translationally modifying a protein of interest via using isolated or partially purified glycosyltransferases and/or post-translational modification proteins, extracts of cells comprising glycosyltransferases and/or post-translational modification proteins, and/or in cells comprising one or more glycosyltransferases and/or post-translational modification proteins. |
US08969030B2 |
Process to produce biodiesel and/or fuel oil
The present invention refers to a process to produce biodiesel and/or fuel oil from microbial oilseed and/or algal biomass and/or from sugar cane residues and derivatives. The products according to the present invention are appropriate for direct use in motors and to generate energy or steam. The integrated process of the present invention comprises the use, as raw materials, of microbial oil-producing biomass obtained from sugar cane residues and derivatives, which is integrated with algal biomass and/or glycerol and are processed by steps of production of oil-producing microbial biomass from filamentous fungi and/or yeasts, steps of simultaneous production of algal biomass by fully using residues, CO2 and residual broth of said production of microbial biomass, as well as steps of extraction and transesterification of lipids contained in the biomass, with reuse of the residual glycerol thus produced. The process as disclosed deals with innovative and ecologically sustainable technology, not generating any kind of residue, also providing for the advantage of releasing considerable volumes of oxygen into the atmosphere. |
US08969029B2 |
Biological sterilization indicator, system, and methods of using same
A biological sterilization indicator, system, and methods of determining the effectiveness of a sterilization process. The biological sterilization indicator can include a locus of spores, a reservoir containing a liquid, and a sterilant path positioned to provide fluid communication between ambience and the locus of spores. The reservoir can have a closed state in which the reservoir is not in fluid communication with the locus of spores and an open state in which the reservoir is in fluid communication with the locus of spores. The biological sterilization indicator system can include the biological sterilization indicator and a detection device adapted to be coupled to the biological sterilization indicator. In some embodiments, the method can include assaying the spores for a detectable change in a characteristic, and detecting substantially all of the detectable change. |
US08969027B2 |
Protease assay
The present invention provides a diagnostic reagent or assay for assessing the activity of a protease in vivo or in vitro and methods of detecting the presence of a cancerous or precancerous cell. The assays are comprised of two particles linked via an oligopeptide linkage that comprises a consensus sequence specific for the target protease. Cleavage of the sequence by the target protease can be detected visually or using various sensors, and the diagnostic results can be correlated with cancer prognosis. |
US08969023B2 |
Methods and compositions for treating alzheimer's disease
Aspects of the invention relate to methods and compositions for treating Alzheimer's disease (AD). In some embodiments, the invention provides methods for screening and identifying compounds that selectively inhibit the targeting of the insulin-Akt signaling pathway by Aβ oligomers. |
US08969021B2 |
Methods and compositions for detecting non-hematopoietic cells from a blood sample
The present invention recognizes that diagnosis and prognosis of many conditions can depend on the enrichment of rare cells, especially tumor cells, from a complex fluid sample such as a blood sample. In particular, the present invention is directed to methods and compositions for detecting a non-hematopoietic cell, e.g., a non-hematopoietic tumor cell, in a blood sample via, inter alia, removing red blood cells (RBCs) from a blood sample using a non-centrifugation procedure, removing white blood cells (WBCs) from said blood sample to enrich a non-hematopoietic cell, if any, from said blood sample; and assessing the presence, absence and/or amount of said enriched non-hematopoietic cell. |
US08969011B2 |
Microorganism concentration process and device
A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration device comprising a sintered porous polymer matrix comprising at least one concentration agent that comprises an amorphous metal silicate and that has a surface composition having a metal atom to silicon atom ratio of less than or equal to 0.5, as determined by X-ray photoelectron spectroscopy (XPS); (b) providing a sample comprising at least one microorganism strain; and (c) contacting the concentration device with the sample such that at least a portion of the at least one microorganism strain is bound to or captured by the concentration device. |
US08969010B2 |
In vivo micro-invasive investigation device including a metal guide
The invention relates to an analysis device, wherein said system includes at least one metal guide at one end of which is provided at least one series of pits to which are directly coupled reagents specific to a substrate, said end being a perforating one, while the other end is intended for controlling said guide and is optionally associated with a suction system. The guide may be inserted into a protection system that is removable at the level of the functionalized end, up to the micro-analysis and/or micro-sampling site, and/or into a medical instrument having an inner channel in which said guide may slide. The present invention also relates to the use of such a device for making a tool for diagnosing cancer, an inflammation, an infection, a neurodegenerative disease or a graft rejection in a patient, preferably by transparietal delivery. The invention further relates to a method for the ex vivo analysis of a substrate using such a device. |
US08969008B2 |
Genotoxic testing
The present invention relates to methods for detecting for the presence of an agent that putatively causes or potentiates DNA damage comprising subjecting a cell (containing a DNA sequence encoding a reporter protein operatively linked to a human GADD45α gene promoter and a human GADD45α gene regulatory element arranged to activate expression of the DNA sequence in response to DNA damage) to an agent; and monitoring the expression of the reporter protein from the cell. The invention also concerns expression cassettes, vectors and cells which may be used according to such a method and also modified media that may be employed in fluorescence assays and in preferred embodiments of the method of the invention. |
US08968997B2 |
Benzoxazole-based fluorescent metal ion indicators
Disclosed are benzoxazole-based compounds, kits, and methods of producing and using the described compounds in fluorescence-based detection of analytes (e.g., metal ions). Also disclosed are uses of benzoxazole-based compounds as ratiometric metal ion indicators. |
US08968994B2 |
Method for stem cell culture and cells derived therefrom
There is described a method of promoting the attachment, survival and/or proliferation of a stem cell in culture, the method comprising culturing a stem cell on a positively-charged support surface. There are also provided a cell composition prepared according to the method of the invention. |
US08968984B2 |
Photosensitive resin composition
Disclosed is a photosensitive resin composition for an organic insulating layer. More specifically, the photosensitive resin composition is suitable for forming a substrate of a transflective thin film transistor liquid crystal display (TFT-LCD) or a pattern of an interlayer insulating layer by improving remarkably a pattern property with a high taper angle besides improvement of flatness, sensitivity, heat resistance, and transparency. Particularly, the photosensitive resin composition can provide low power dissipation besides a wide viewing angle and high visibility when being applied to a transflective type display. In addition, the photosensitive resin composition can provide a clear screen under natural light without a backlight by maintaining the brightness of a screen and prominent field visibility. |
US08968980B2 |
Radiation-sensitive resin composition and compound
A radiation-sensitive resin composition includes an acid-dissociable group-containing resin, and a compound shown by the following general formula (1). wherein Z− represents a monovalent anion shown by a general formula (2), M+ represents a monovalent onium cation, R1 represents a linear or branched alkyl group having 1 to 12 carbon atoms substituted or unsubstantiated with a fluorine atom, or a linear or branched alkoxy group having 1 to 12 carbon atoms, and n is 1 or 2. |
US08968979B2 |
Positive resist composition and patterning process
A positive resist composition comprises a polymer comprising repeat units having formula (1) or (2). Herein denotes an aromatic hydrocarbon group, R1 is H, methyl or trifluoromethyl, R2 is H, C1-C12 alkyl or aromatic hydrocarbon group, R3 is C1-C12 alkyl, or R2 and R3 may bond together to form a ring, and a is 1 or 2. When used in the ArF lithography, the resist composition exhibits high resolution. When used in the EB image writing for mask processing, the resist composition exhibits high resolution and sensitivity sufficient to comply with high-accelerating-voltage EB irradiation, and high etch resistance. |
US08968974B2 |
Techniques for coating print media
Techniques for coating print media are described herein. In an example, a photo imaging assembly is to receive a liquid electrophoretic coating composition assembly on a chargeable surface so as to form a coating layer thereon using electrostatic forces. The coating layer is to be transferred to a print medium. |
US08968973B2 |
Color filter and production method thereof, and solid-state image sensor using the same
A method of producing a color filter includes (a) forming a colored pattern on a substrate by exposing and developing a colored curable composition containing a dye, a polymerizable monomer and an organic solvent, (b) forming a transparent protective film on the colored pattern, and (c) irradiating at least the transparent protective film with light after forming the transparent protective film on the colored pattern. |
US08968972B2 |
Photomask blank, process for production of photomask, and chromium-containing material film
In the chromium-containing material film of the present invention, an element is added thereto and is capable of bringing a mixture of the element and the chromium into a liquid phase at a temperature of 400° C. or lower. The use of such a chromium-containing material film as an optical film (e.g., a light-shielding film, an etching mask film, or an etching stopper film) of a photo mask blank can achieve an improvement in chlorine-dry etching while retaining the same optical characteristics and the like as those of the conventional chromium-containing material film, thereby increasing the patterning precision. |
US08968968B2 |
Substantially flat single cells for SOFC stacks
A solid oxide fuel cell includes an anode layer, a cathode layer, and an electrolyte layer partitioning the anode layer and the cathode layer. The anode layer and the cathode layer are of about the same thickness and have about the same coefficient of thermal expansion (CTE). |
US08968967B2 |
Fuel cell catalyst support with fluoride-doped metal oxides/phosphates and method of manufacturing same
A fuel cell catalyst support includes a fluoride-doped metal oxide/phosphate support structure and a catalyst layer, supported on such fluoride-doped support structure. In one example, the support structure is a sub-stechiometric titanium oxide and/or indium-tin oxide (ITO) partially coated or mixed with a fluoride-doped metal oxide or metal phosphate. In another example, the support structure is fluoride-doped and mixed with at least one of low surface carbon, boron-doped diamond, carbides, borides, and silicides. |
US08968966B2 |
Fuel battery
Provided is a fuel battery including: a fuel battery cell assembly having at least two fuel battery cells coplanarly disposed, the fuel battery cell including a membrane electrode assembly having an anode, an electrolytic membrane, and a cathode stacked on one another in this order, and a flow channel plate provided on an anode side and having on an anode-side surface thereof an in-cell fuel flow channel through which liquid fuel flows; and a fuel distributor having an out-cell fuel flow channel connected to each of the in-cell fuel flow channels to distribute the liquid fuel to the fuel battery cells. |
US08968965B2 |
Curable compositions and membranes
A curable composition comprising: (i) 2.5 to 50 wt % crosslinker comprising at least two acrylamide groups; (ii) 12 to 65 wt % curable ionic compound comprising an ethylenically unsaturated group and a cationic group; (iii) 10 to 70 wt % solvent; and (iv) 0 to 10 wt % of free radical initiator; and (v) non-curable salt; wherein the molar ratio of (i):(ii) is >0.10. The compositions are useful for preparing ion exchange membranes. |
US08968959B2 |
Method for fabrication of electrochemical energy converter and the electrochemical energy converter
In a method for fabrication of an electrochemical energy converter, cermet composition layers (2A), (2B) are applied on both sides of a central ceramic plate (1), channels (3A), (3B) are made in the cermet composition layers (2A), (2B), then the channels (3A), (3B) on both sides of the plate are covered with cermet composition layers (4A), (4B). Afterwards, both sides of the ceramic structure are overlaid with conductive structures (5A), (5B) and then with subsequent layers of the cermet composition (6A), (6B) containing nickel, then both sides of the ceramic structure are overlaid with: layers constituting the solid electrolyte (7A), (7B), layers constituting electrodes (8A), (8B) and contact layers (9A), (9B). |
US08968958B2 |
Voltage lead jumper connected fuel cell columns
A fuel cell system includes a plurality of fuel cell stacks, and one or more devices which in operation of the system provide an azimuthal direction to one or more anode or cathode feed or exhaust fluid flows in the system. |
US08968957B2 |
Fuel cell
A fuel cell unit configuring a fuel cell is provided with a first separator, a first electrolyte film/electrode body, a second separator, a second electrolyte film/electrode body, and a third separator. Resin guide members are provided on the outer periphery of the first separator, the second separator, and the third separator. The resin guide members have outer peripheral ends which protrude outwards, and in the aforementioned resin guide members are formed concave reliefs which are spaced inwards from the aforementioned outer peripheral ends. |
US08968954B2 |
Fuel cell system and method of controlling reaction condition of fuel in fuel cell
A target value of each of factors in a fuel cell system is determined based on a correspondence relationship of a change in each of the factors determining reaction conditions of fuel in a fuel cell to a change in an external environment of the fuel cell system, and peripheral devices of the fuel cell affecting the reaction conditions of the fuel in the fuel cell are controlled according to a target value of each of the factors. |
US08968951B2 |
Intelligent system for the dynamic modeling and operation of fuel cells
A system and method for controlling an output of a dynamic fuel cell is provided. A dynamic fuel cell has a membrane wherein a dimension of the membrane is variable during operation of the dynamic fuel cell in response to a control signal from an intelligent controller. By varying the dimension of the membrane, the output voltage of the dynamic fuel cell can be altered. An intelligent controller is provided that can measure a number of outputs and input parameters of the dynamic fuel cell and approximate input parameters using the measured values to adjust the input of the dynamic fuel cell to the approximated values. |
US08968950B2 |
Method of starting operation of solid polymer electrolyte fuel cell
A method of starting operation of a fuel cell stack includes the steps of performing gas replacement by supplying a fuel gas to a fuel gas flow field from a downstream side of the fuel gas flow field through a fuel gas discharge passage, and supplying an oxygen-containing gas to an oxygen-containing gas flow field from an upstream side of the oxygen-containing gas flow field through an oxygen-containing gas supply passage. After the step of performing gas replacement, normal power generation is carried out by supplying the fuel gas to the fuel gas flow field from an upstream side of the fuel gas flow field through a fuel gas supply passage, and supplying the oxygen-containing gas to the oxygen-containing gas flow field from the upstream side of the oxygen-containing gas flow field through the oxygen-containing gas supply passage. |
US08968949B2 |
Method of withdrawing heat from a battery pack
A method for withdrawing heat from a battery pack is provided, wherein the heat is transferred from at least one electrode of each cell comprising the battery pack, via an electrically and thermally conductive tab, through a current collector plate and through a thermal interface layer to a temperature control panel that is coupled to an external temperature control system. |
US08968948B2 |
Energy generation system and related uses thereof
A self contained energy generating system that comprises a galvanic battery and a power distribution system. The energy generating system is used to purify water by using a reverse osmosis device that draws in a source of water and transfers electrolytes to the galvanic battery. Upon contact with the electrolyte, the galvanic battery produces energy by an oxidation-reduction reaction of the cathode and anode and transfers energy to the power distribution system, which in turn provides power to the osmosis device. Additionally, the system includes a hydrogen fuel cell to increase the amount of energy generated and a power storage device for storing excess energy generated. The system also includes a controller which is configured to regulate the overall operation of the system. |
US08968942B2 |
Metal oxygen battery containing oxygen storage materials
A battery system includes a metal oxygen battery. The metal oxygen battery includes a first electrode and a second electrode. The second electrode includes a metal material (M). The metal oxygen battery is in communication with an oxygen storage material. In certain instances, the oxygen storage material is contained within an oxygen containment unit. The metal oxygen battery and the oxygen containment unit may be in a closed-loop with respect to each other. The battery system further includes a conduit for providing fluid communication from one of the metal oxygen battery and the oxygen containment unit to the other of the metal oxygen battery and the oxygen containment unit. |
US08968941B2 |
Li-air batteries having ether-based electrolytes
A lithium-air battery includes a cathode including a porous active carbon material, a separator, an anode including lithium, and an electrolyte including a lithium salt and polyalkylene glycol ether, where the porous active carbon material is free of a metal-based catalyst. |
US08968940B2 |
Redox shuttles for high voltage cathodes
A compound has general Formula I, II, III, or IV: where X and Y are independently a group of Formula (A): and Z a group of Formula (B): The compounds may be used in electrolytes and electrochemical devices. |
US08968937B2 |
Anode for secondary battery and secondary battery having the same
The present invention relates to an anode for a secondary battery, comprising at least two anode wires which are parallel to each other and spirally twisted, each of the anode wires having an anode active material layer coated on the surface of a wire-type current collector; and a secondary battery comprising the anode. The anode of the present invention has an increased surface area to react with Li ions during a charging and discharging process, thereby improving the rate characteristics of a battery, and also release stress or pressure applied in the battery, e.g., the volume expansion of active material layers to prevent the deformation of the battery and ensure the stability thereof, thereby improving the life characteristic of the battery. |
US08968936B2 |
Method for producing lithium-containing composite oxide
The present invention provides a method for producing a lithium-containing composite oxide represented by general formula (1) below, the method at least including a step of preparing a solution by dissolving a lithium source, an element M source, a phosphorus source, and an element X source that serve as source materials in a solvent, the phosphorus source being added after at least the element M source is dissolved; a step of gelating the resulting solution; and a step of calcining the resulting gel: LixMyP1-zXzO4 (1) (where M represents at least one element selected from the group consisting of Fe, Ni, Mn, Zr, Sn, Al, and Y; X represents at least one element selected from the group consisting of Si and Al; and 0 |
US08968934B2 |
Electrode for secondary battery, fabrication method thereof, and secondary battery comprising same
The present invention relates to an electrode for a secondary battery, comprising a collector and a porous electrode active material layer disposed on at least one surface of the collector by spraying metal oxide nanoparticle dispersion, wherein the porous electrode active material comprises one selected from the group consisting of aggregated metal oxide nanoparticles, metal oxide nanoparticles and a mixture thereof, which is capable of undergoing stable high speed charging/discharging cycles under a high-energy-density and high-current condition. |
US08968933B2 |
Process for preparation of anode active material
Disclosed is a method for preparing an anode active material comprising a core composed of a crystalline carbon-based material, and a composite coating layer comprising (a) mixing a precursor for a raw material of one or more materials selected from the group consisting of low crystalline carbon and amorphous carbon with silicon oxide enabling intercalation and deintercalation of ions, followed by purification, to prepare a mixture for coating, (b) mixing the mixture for coating with a crystalline carbon-based material to prepare a core-shell precursor comprising the raw material mixture for coating applied to the core composed of the crystalline carbon-based material, and (c) baking the core-shell precursor to carbonize the raw material of the one or more materials selected from the group consisting of low crystalline carbon and amorphous carbon into the one or more materials selected from the group consisting of low crystalline carbon and amorphous carbon. |
US08968929B2 |
Silicon clathrate anodes for lithium-ion batteries
The present disclosure is directed at an electrode and methods for forming such electrode for a battery wherein the electrode comprises silicon clathrate. The silicon clathrate may include silicon clathrate Si46 containing an arrangement of 20-atom and 24-atom cages fused together through 5 atom pentagonal rings and/or silicon clathrate Si34 containing an arrangement of 20-atom and 28-atom cages fused together through 5 atom pentagonal rings. The silicon clathrate may be present as particles having a largest linear dimension in the range of 0.1 μm to 100.0 μm. |
US08968925B2 |
Metal-doped transition metal hexacyanoferrate (TMHCF) battery electrode
A method is provided for synthesizing a metal-doped transition metal hexacyanoferrate (TMHCF) battery electrode. The method prepares a first solution of AxFe(CN)6 and Fe(CN)6, where A cations may be alkali or alkaline-earth cations. The method adds the first solution to a second solution containing M-ions and M′-ions. M is a transition metal, and M′ is a metal dopant. Subsequent to stirring, the mixture is precipitated to form AxMcM′dFez(CN)n.mH2O particles. The AxMcM′dFez(CN)n.mH2O particles have a framework and interstitial spaces in the framework, where M and M′ occupy positions in the framework. Alternatively, the method prepares AaA′bMyFez(CN)n.mH2O particles. A and A′ occupy interstitial spaces in the AaA′bMyFez(CN)n.mH2O particle framework. A metal-doped TMHCF electrode is also provided. |
US08968921B2 |
Fluoride ion electrochemical cell
Electrochemical cells of the present invention are versatile and include primary and secondary cells useful for a range of important applications including use in portable electronic devices. Electrochemical cells of the present invention also exhibit enhanced safety and stability relative to conventional state of the art primary lithium batteries and lithium ion secondary batteries. For example, electrochemical cells of the present invention include secondary electrochemical cells using anion charge carriers capable of accommodation by positive and negative electrodes comprising anion host materials, which entirely eliminate the need for metallic lithium or dissolved lithium ion in these systems. |
US08968920B2 |
Organic electrolyte solution including silane compound and lithium battery employing the same
Organic electrolyte solutions and lithium batteries employing the same are provided. In one embodiment, an organic electrolyte solution includes a silane compound. The inventive organic electrolyte solutions prevent crack formation caused by volumetric changes in the anode active material during charging/discharging of the battery. This improves charge/discharge characteristics, resulting in improved battery stability, reliability, and charge/discharge efficiency, which is a dramatic improvement over conventional organic electrolyte solutions, which have higher irreversible capacities due to the decomposition of polar solvents. |
US08968913B2 |
Rechargeable battery pack for an electrical load
The invention is directed to a rechargeable battery pack for an electrical load with the load being connected to the rechargeable battery pack by a connection cable. A housing of the rechargeable battery pack has an inner space for accommodating a large number of rechargeable individual cells which are electrically connected to one another and supply the load via the connection cable. To provide the housing with a high level of stability, provision is made for the receiving space in the housing to be subdivided into individual receptacles by partition walls. A cell pack includes a predefined number of the individual cells and is arranged in a corresponding individual receptacle. Each cell pack forms an independent unit which is held in the individual receptacle. The individual cells of a cell pack are electrically and mechanically connected to one another by cell connectors. |
US08968905B2 |
Secondary battery
A secondary battery including an electrode assembly, the electrode assembly including a positive electrode plate, a negative electrode plate, and a separator; a pouch accommodating the electrode assembly; and a dissipation member, the dissipation member contacting the electrode assembly and protruding to an exterior of the pouch from an interior of the pouch. |
US08968900B2 |
Flexible sleeve battery holder apparatus and method
A battery holder apparatus and method includes a sleeve with an inside surface and an outside surface where the sleeve is flexible. A battery receiving space is created within the sleeve where the battery receiving space expands and the sleeve flexes to accommodate a battery when inserted therein and the inside surface at least partially contacts the battery. And a connection device is provided on the outside surface of the sleeve. |
US08968898B2 |
Cap assembly of novel structure and cylindrical battery employed with the same
Disclosed herein is a cap assembly disposed at an open upper end of a cylindrical container of a battery in which an electrode assembly (jelly roll) of a cathode/separator/anode structure is mounted in the cylindrical container, wherein an electrode lead of the jelly roll is electrically connected to the lower end of a safety vent having notches, which are ruptured to discharge high pressure gas when high pressure is generated in the battery, and a safety element to interrupt current at a predetermined temperature is provided between the safety vent and the electrode lead. |
US08968896B1 |
Mitigation of internal shorting for improved battery safety
The present disclosure teaches a method, system, and apparatus for the mitigation of internal shorting for improved battery safety. In one or more embodiments, the disclosed method for mitigating internal shorting in a battery involves sensing, with at least one sensor, an internal shorting condition of the battery. The method further involves producing, by at least one processor, at least one commanding signal to initiate motion of a filament breaking mesh. Also, the method involves moving, by at least one drive mechanism, the filament breaking mesh, upon receiving at least one commanding signal. Further, the method involves breaking, with the filament breaking mesh, at least one filament present within the battery. |
US08968892B2 |
Battery pack
A battery pack includes a plurality of bare cells electrically connected in series or parallel to one another, and a protection circuit module provided with a thermistor. In the battery pack, the protection circuit module is electrically connected to the bare cells, and the thermistor is provided to be parallel in the length direction of the protection circuit module between the bare cells and the protection circuit module so as to measure a variable resistance by sensing a temperature of the bare cells and to transfer the measured resistance as an electrical signal to the protection circuit module. |
US08968888B2 |
Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device
A novel compound having high triplet excitation energy and a bipolar property is provided. Specifically, a phenanthrene compound represented by General Formula (G1) is provided where R11 to R19 and R21 to R27 separately represent any one of hydrogen, an alkyl group having 1 to 4 carbon atoms, and a substituted or unsubstituted aryl group having 6 to 13 carbon atoms, Ar represents a substituted or unsubstituted arylene group having 6 to 13 carbon atoms, and Z represents a sulfur atom or an oxygen atom. The use of the phenanthrene compound as a host material of a light-emitting layer in the presence of a phosphorescent dopant allows the formation of a light-emitting element with high current efficiency. |
US08968877B2 |
Barrier materials for mirror assemblies
Provided herein is a reflective optical construction containing a fluoropolymer barrier layer, wherein the fluoropolymer is selected from the group consisting of homopolymers and copolymers of at least one tetrafluoropropene or pentafluoropropene, preferably 2,3,3,3-tetrafluoropropene. Also disclosed is a method of forming a reflective optical construction including (a) applying a barrier layer comprising one or more fluoropolymers selected from the group consisting of homopolymers and copolymers of at least one tetrafluoropropene or pentafluoropropene, and (b) curing. |
US08968872B2 |
Encapsulated agglomeration of microcapsules and method for the preparation thereof
Microcapsules comprising an agglomeration of primary microcapsules, each individual primary microcapsule having a primary shell and the agglomeration being encapsulated by an outer shell, may be prepared by providing an aqueous mixture of a loading substance and a shell material, adjusting pH, temperature, concentration and/or mixing speed to form primary shells of shell material around the loading substance and cooling the aqueous mixture until the primary shells agglomerate and an outer shell of shell material forms around the agglomeration. Such microcapsules are useful for storing a substance and for delivering the substance to a desired environment. |
US08968867B2 |
Horizontal thermoelectric tape and method for manufacturing same
The present invention relates to a horizontal thermoelectric tape and a method for manufacturing same, and more particularly, to a horizontal thermoelectric tape for an effective blocking of an electromagnetic wave and an excellent heat dissipation effect. The horizontal thermoelectric tape of the present invention unifies the double layer structure of an adhesion layer and a heat dissipation layer, more effectively achieving the heat dissipation effect, and simplifying the manufacturing process thereof, and by using a non-evaporated metal foil as a conductive base material, enables a horizontal thermoelectric tape having an excellent heat conductivity, and using a conductive base material not containing impurities. |
US08968861B2 |
Flame retardant, electrically conductive adhesive materials and related methods
Disclosed are exemplary embodiments of a flame retardant, electrically conductive adhesive material. In an exemplary embodiment, a flame retardant, electrically conductive adhesive material suitable for use as tape generally includes a layer of adhesive. A layer of electrically conductive fabric is on the layer of adhesive. A flame retardant coating is on the layer of electrically conductive fabric. The flame retardant coating includes a carbon-containing resin. |
US08968859B2 |
Heat extensible fiber
A heat extensible fiber comprises a conjugate fiber including a first resin component having an orientation index of 30% to 70% and a second resin component having a lower melting point or softening point than the melting point of the first resin component and an orientation index of 40% or more, the second resin component being present on at least part of the surface of the conjugate fiber in a lengthwise continuous configuration. The conjugate fiber is a heat-treated or crimped fiber and being configured to thermally extend when heated at a temperature lower than the melting point of the first resin component. The heat extensible fiber has higher heat self-extensibility than conventional extensible fibers. |
US08968857B2 |
High hardness imprint material
There is provided an imprint material from which a film having a high hardness can be formed. An imprint material comprising a component (A), a component (B) and a component (C), the component (A) being a compound having, in the molecule thereof, five or more polymerizable groups, the component (B) being a compound having, in the molecule thereof, two polymerizable groups, and the component (C) being a photo-radical generator. |
US08968853B2 |
Pressure-sensitive adhesives including expandable graphite
A building material comprising a substrate layer and a pressure-sensitive adhesive layer, where the pressure-sensitive adhesive layer includes expandable graphite. |
US08968849B2 |
Polyester composition for improved stress crack resistance in polyester articles
Polyester compositions for use in injection stretch blow molded articles having intrinsic viscosities in the range from about 0.65 to about 0.78 dl/g, and carboxyl end group concentrations of about 47 mmole/kg or more are provided. Stretch blow molded articles formed from these polyester compositions and methods to produce these articles are also described. |
US08968848B2 |
Induction heating system
An induction heating system includes a first heating surface and an induction coil located adjacent the first heating surface. The induction heating system also includes food packaging configured to be placed on the first heating surface. The food packaging contains a current conducting material such that the food packaging is inductively heated to a temperature sufficient to heat food when the induction coil is energized. |
US08968847B2 |
Flexible packaging materials and methods of making and using same
Packaging materials are disclosed, along with packages formed therefrom and methods for forming the packages. |
US08968845B2 |
Thermal transfer film
A thermal transfer film and a method of manufacturing an OLED display, the thermal transfer film including a light to heat conversion layer, the light to heat conversion layer being formed of a composition including carbon black having an oil absorption number (OAN) of about 50 cc/100 gram to about 120 cc/100 gram and a mean particle size of about 40 nm to about 200 nm; and a binder. |
US08968844B2 |
Recording medium and image recording process
A recording medium includes a base and an ink receiving layer. The ink receiving layer contains inorganic particles. The surface of the recording medium has an arithmetic mean roughness of 0.8 μm or more in accordance with JIS B 0601:2001. The surface of the recording medium includes openings having a width of 30 μm or less and a length of 500 μm or less. The number of the openings is 5 or more and 30 or less per 1 mm2 of the surface of the recording medium. |
US08968841B2 |
Binaphthyl compound, liquid crystal composition, liquid crystal element, and liquid crystal display device
A binaphthyl compound represented by General Formula (G1) is provided. In General Formula (G1), Ar2 represents any of an arylene group, a cycloalkylene group, and a cycloalkenylene group, and m is any of 0 to 3; R3 represents any of hydrogen, an alkyl group, and an alkoxy group; and one of R and R1 represents a substituent represented by General Formula (G2) and the other thereof represents hydrogen. In General Formula (G2), Ar1 represents any of an arylene group, a cycloalkylene group, and a cycloalkenylene group, and k is any of 1 to 3; and R2 represents any of hydrogen, an alkyl group, and an alkoxy group. |
US08968840B2 |
Liquid-crystalline medium
The present invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy (Δ∈), which is distinguished by the fact that it has a value for the ratio γ1/Δn2 in the range 6-45 with a clearing point of >60° C. and a Δ∈ of ≦−2.3. Media of this type are particularly suitable for electro-optical displays having active-matrix addressing based on the ECB, PA LCD, FFS or IPS effect. |
US08968837B2 |
Method for the plasma-enhanced treatment of internal surfaces of a hollow body, fluid separator, and use thereof
The present invention relates to the treatment of internal surfaces of a hollow body, on the inner surfaces of which areas having different surface properties, for example, having hydrophilic and hydrophobic properties, are produced. The invention further relates to fluid separators that are based on said hollow bodies and that have areas having different surface properties. Such fluid separators are used in medical technology and analysis, in particular biochemical analysis. |
US08968828B2 |
Composite polyamide membrane
A method for making a composite polyamide membrane comprising the steps of applying a polyfunctional amine monomer and polyfunctional acyl halide monomer to a surface of the porous support and interfacially polymerizing the monomers to form a thin film polyamide layer, wherein the method is includes at least one of the following steps: i) conducting the interfacial polymerization in the presence of a C2-C20 aliphatic monomer comprising at least one carboxylic acid functional group or salt thereof, and a single amine-reactive functional group; and ii) applying a C2-C20 aliphatic monomer comprising at least one carboxylic acid functional group or salt thereof, and a single amine-reactive functional group to the thin film polyamide layer. Many additional embodiments are described including applications for such membranes. |
US08968823B2 |
Method of manufacturing a light emitting device
Disclosed is an evaporation method to form a thin film over a substrate, which is characterized in the use of an evaporation source equipped with a plurality of evaporation cells. The evaporation source has a rectangular shape with a long side and a short side wherein the long side is longer than the short side. At least one of the evaporation source and the substrate is relatively moved during the evaporation, which allows the formation of a thin film having a highly uniform thickness in a short time. |
US08968815B2 |
Method for producing fats and oils
The present invention discloses a safer, more effective and industrially suitable method for producing fats and oils rich in a XUX triglyceride wherein the contents of a XXX triglyceride and a XX diglyceride are low which comprises, upon removing by crystallization a XXX triglyceride and a XX diglyceride each of which is contained in fats and oils comprising 50 to 90 mass % of a XUX triglyceride in total triglycerides, the step of conducting such removing by crystallization in the presence of a fatty acid lower alkyl ester. This method is a more efficient and industrially suitable method for producing fats and oils rich in a XUX triglyceride wherein the contents of a XXX triglyceride and a XX diglyceride are low. |
US08968814B2 |
Method for preventing scorching of milk-based product
The invention relates to a method for manufacturing a milk-based product from which whey proteins such as beta lactoglobulm have been substantially removed, and to the use of such a product as a milk product to be heated in cooking. |
US08968812B2 |
Method for producing a mixed product
The invention relates to a method for producing a liquid mixed product from at least one liquid base component and at least one liquid additive, which is added to the base component in a metered manner, wherein the at least one liquid additive is metered into the base component depending on the amount of the mixed product removed from the mixing chamber (2.3). |
US08968807B1 |
Use of ethylene diamine metal complexes to deliver highly absorbable metals for animal nutrition
Use of ethylene diamine metal complexes, preferably of copper, zinc, iron and manganese in highly absorbable formats for animal nutrition. |
US08968804B2 |
Methods for managing weight loss and body mass
The invention provides methods for promoting weight loss by an animal, promoting weight loss by an animal while preventing or minimizing loss of lean body mass by the animal, preventing a reduction in energy metabolism by an animal, reducing the risk of regaining weight by an animal after weight loss, and ameliorating undesirable animal behaviors associated with reduced caloric intake by intermittently feeding an animal a first diet containing calories that meet the animal's maintenance energy requirements and a second diet containing calories that do not meet the animal's maintenance energy requirements. In preferred embodiments, the described feeding pattern and diets are fed in conjunction with one or more weight loss agents. |
US08968800B2 |
Application of american ginseng to enhance neurocognitive function
Disclosed are methods of enhancing neurocognitive function by administering of American Ginseng. Preferred dosages in the range of 5 to 50 mg total genosides enhance cognitive function—including, improvement of working memory (WM) performance, attentional performance (e.g., Choice Reaction Time accuracy), and calmness. |
US08968794B2 |
Antiseptic compositions and uses thereof
Antiseptic compositions and kits containing a source of silver ions and menthol, which act in synergy such that a concentration of silver ions in the composition is substantially reduced, are disclosed. Further disclosed are uses of the antiseptic compositions as disinfectants and in the treatment of wounds. |
US08968791B2 |
Dietary supplements for promotion of growth, repair, and maintenance of bone and joints
The present invention provides a dietary supplement that promote the growth, repair, and maintenance of mammalian bone and joint connective tissue. In particular, the dietary supplement comprises a combination of at least one metal chelate and at least one chondroprotective agent. |
US08968787B2 |
Composition comprising biodegradable polymers for use in a cosmetic composition
The present invention relates to certain novel polymer powder compositions suitable for personal care and cosmetic compositions. The present invention also relates to cosmetic compositions comprising such novel polymer powders. The present invention also relates to processes for manufacturing the polymer powders, methods of making cosmetic and personal care compositions and the use of such cosmetic compositions in topical applications. |
US08968784B2 |
Method for preparing hydro/organo gelators from disaccharide sugars by biocatalysis and their use in enzyme-triggered drug delivery
A method for preparing hydro/organo gelators from disaccharide sugars by biocatalysis and their use in enzyme-triggered drug delivery. Controlled delivery of an anti-inflammatory, chemopreventive drug is achieved by an enzyme-triggered drug release mechanism via degradation of encapsulated hydrogels. The hydro- and organo-gelators are synthesized in high yields from renewable resources by using a regioselective enzyme catalysis and a known chemopreventive and anti-inflammatory drug, curcumin, is encapsulated in the gel matrix and released by enzyme triggered delivery. The release of the drug occurs at the physiological temperature and control of the drug release rate is achieved by manipulating the enzyme concentration and temperature. The by-products formed after the gel degradation clearly demonstrated the site specificity of degradation of the gelator by enzyme catalysis. The present invention has applications in developing cost effective, controlled drug delivery vehicles from renewable resources, with a potential impact on pharmaceutical research and molecular design and delivery strategies. |
US08968779B2 |
Controlled release coat-core tablet
Disclosed is a controlled release nucleated tablet which is composed of an inner nucleus and an outer layer that covers the inner nucleus and is capable of maintaining the level of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid in the blood to a certain value or higher for a long period of time. The controlled release nucleated tablet is characterized in that the inner nucleus contains 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid and the outer layer contains 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid and a gel-forming water-soluble polymer that is in an amount of 16 (w/w) % or more relative to the weight of the outer layer. |
US08968777B2 |
Tranexamic acid formulations with reduced adverse effects
Tranexamic acid formulated in an oral dosage form with at least one agent that decreases tranexamic acid release in the stomach. Such formulations minimize nausea, vomiting, and other adverse gastric effects that may accompany tranexamic acid therapy, for example, to treat heavy menstrual bleeding. One embodiment is an extended release formulation with waxes, polymers, etc. that prevent a bolus release of tranexamic acid in the stomach. An alternative embodiment is a delayed release formulation with polymers that prevent release of tranexamic acid in the acid environment of the stomach and delay its release until the formulation reaches the less acid environment of the intestines. Such formulations enhance patient compliance with therapy because adverse effects of tranexamic acid therapy are reduced. |
US08968768B2 |
Phytosterol nutritional supplements
The invention provides a nutritional supplement which includes phytosterol to facilitate reduction of cholesterol. The nutritional supplement may be a swallowable tablet, chewable tablet, sachet, capsule or suspension. The invention further provides a method for tableting one fourth to one half of the daily effective dosage of a phytosterol containing nutritional supplement in a practical sized swallowable tablet and a method for reducing blood cholesterol in humans. |
US08968767B2 |
Drug depots having different release profiles for reducing, preventing or treating pain and inflammation
Effective treatments of pain and/or inflammation are provided. Through the administration of an effective amount of at least analgesic and/or at least one anti-inflammatory agent at or near a target site, one can reduce, prevent or treat inflammation and pain. |
US08968766B2 |
Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods
Biocompatible intraocular implants include a tyrosine kinase inhibitor and a biodegradable polymer that is effective to facilitate release of the tyrosine kinase inhibitor into an eye for an extended period of time. The therapeutic agents of the implants may be associated with a biodegradable polymer matrix, such as a matrix that is substantially free of a polyvinyl alcohol. The implants may be placed in an eye to treat or reduce the occurrence of one or more ocular conditions. |
US08968763B2 |
Block biodegradable copolymers for medical devices
Disclosed herein are implantable medical devices comprising controlled release biodegradable block copolymers or coated with controlled release block copolymers and at least one drug releasable from the block copolymer. The controlled release block copolymers comprise least two blocks selected from the group consisting of polyesters, polyethers, and polyurethanes. |
US08968754B2 |
Titanium dioxide dispersion and cosmetics containing the same
The present invention provides a titanium dioxide dispersion having a good dispersibility and also provides a cosmetic containing the same. The titanium dioxide dispersion comprises (a) a hydrophobized, treated titanium dioxide powder; (b) one or more oils selected from isohexadecane, isododecane, 2-ethylhexyl 2-ethylhexanoate, isononyl isononate, 2-ethylhexyl isononanoate, isononyl 2-ethylhexanoate, and polypropylene glycol dipivalate; and (c) a siloxane compound represented by the following formula (1), preferably polyoxyalkylene/alkyl comodified organopolysiloxane. R1aR2bR3cSiO(4-a-b-c)/2 (1) |
US08968753B2 |
Ceftolozane-tazobactam pharmaceutical compositions
Pharmaceutical compositions can include ceftolozane lyophilized in the absence of tazobactam. |
US08968747B2 |
Injection paradigm for administration of botulinum toxins
Disorders such as headaches can be treated by administration of a botulinum toxin to a patient suffering therefrom, such as a migraine headache. A combined a fixed site/fixed dose and an optional follow the pain variable dosage and injection site paradigm is disclosed for optimizing clinical effectiveness of botulinum toxin administration for patients suffering headache, particularly chronic migraine. |
US08968746B2 |
Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation
The present invention is directed to a polymeric carrier cargo complex, comprising as a cargo at least one nucleic acid (molecule) and disulfide-crosslinked cationic components as a (preferably non-toxic and non-immunogenic) polymeric carrier. The inventive polymeric carrier cargo complex allows for both efficient transfection of nucleic acids into cells in vivo and in vitro and/or for induction of an (innate and/or adaptive) immune response, preferably dependent on the nucleic acid to be transported as a cargo. The present invention also provides, pharmaceutical compositions, particularly vaccines and adjuvants, comprising the inventive polymeric carrier cargo complex and optionally an antigen, as well as the use of such the inventive polymeric carrier cargo complex and optionally an antigen for transfecting a cell, a tissue or an organism, for (gene-)therapeutic purposes as disclosed herein, and/or as an immunostimulating agent or adjuvant, e.g. for eliciting an immune response for the treatment or prophylaxis of diseases as mentioned above. Finally, the invention relates to kits containing the inventive polymeric carrier cargo complex and/or the inventive pharmaceutical composition, adjuvant or vaccine in one or more parts of the kit. |
US08968744B2 |
Aqueous composition comprising a biological antigen and an acrylic acid polymer
The current invention pertains to an aqueous composition containing a biological antigen and an acrylic acid polymer, wherein the composition comprises an electrolyte to provide an osmolarity higher than the osmolarity of a 0.9% (w/v) sodium chloride solution in water. The invention also pertains to the acrylic acid polymer for use in a one shot vaccine against porcine circo virus 2 (PCV2) and optionally Mycoplasma hyopneumoniae and in an aqueous composition for reducing fever induced by the biological antigens present in the aqueous composition when the composition is administered to a subject animal. |
US08968741B2 |
Anti-CD22 antibodies and immunoconjugates and methods of use
Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided. |
US08968734B2 |
Protofibril-binding antibodies and their use in therapeutic and diagnostic methods for Parkinson's disease, dementia with lewy bodies and other α-synucleinopathies
Antibodies and fragments thereof have high affinity for human α-synuclein protofibrils and low binding of α-synuclein monomers, wherein the antibodies or fragments have specified Complementarity Determining Region (CDR) sequences. Compositions comprise such an antibody or fragment and methods of detecting α-synuclein protofibrils use such an antibody or fragment. In further embodiments, methods of preventing, delaying onset of or treating a neurodegenerative disorder with α-synuclein pathology comprise administering such an antibody or fragment, and such an antibody or fragment is used in the manufacture of a pharmaceutical composition for treatment of a neurodegenerative disorder with α-synuclein pathology. Such an antibody or fragment is used in the diagnosis or monitoring of the development of a neurodegenerative disorder with α-synuclein pathology, and in methods for reducing or inhibiting α-synuclein aggregation by administration of such an antibody or fragment. |
US08968733B2 |
Functionalized surgical adhesives
A bioadherent composition includes a first mixture containing a plurality of reactive members of a specific binding pair, said reactive members being bound to a ligand capable of binding a receptor on biological tissue, and a second mixture containing a plurality of complementary reactive members of the specific binding pair, said complementary reactive members being bound to a ligand capable of binding a receptor on biological tissue, said reactive members capable of forming covalent bonds with said complementary reactive members via a reaction selected from Huisgen cycloaddition reactions, Diels-Alder reactions, and/or thiol-alkene reactions. A method for bonding biological tissue involves utilizing the bioadherent composition. |
US08968729B2 |
Date pit composition for the treatment of animals
A method of treating or preventing bacterial infection in an animal comprises administering an effective amount of degraded date pits. Degraded date pits can be produced by the treatment of date pits with fungi. |
US08968727B2 |
Telomerase activity inhibiting peptide and manufacturing method and application thereof
The present invention provides a telomerase activity inhibiting polypeptide. The expression of the polypeptide in tumor cells can inhibit significantly tumor cell telomerase activity, tumor cell growth, and lead to the death of such cells. The present invention further provides a preparation method for the polypeptide and an application thereof in targeted treatments of tumors. |
US08968725B2 |
Genipin cross-linked fibrin gels
The invention provides a genipin cross-linked fibrin gel. The ratio of genipin to fibrin in the gel ranges from about 0.1:1 to about 10:1 (genipin:fibrin). The gel can be hydrogel. Also provided is method for repairing tissue defects by administering the gel to site of tissue defect. |
US08968724B2 |
Compositions suitable for treatment of spinal disease, disorder or condition
The invention relates to the use of viral inactivated-plasma cryoprecipitate concentrate (VIPCC) comprising a suitable fibronectin/fibrinogen ratio for treating a spine disease, disorder or condition such as intervertebral disc degeneration. |
US08968722B2 |
Milk-based nutritional compositions containing lactoferrin and uses thereof
The present disclosure relates to milk-based nutritional compositions comprising lactoferrin and/or a prebiotic component, wherein, when combined, the lactoferrin and prebiotic component may exhibit additive or synergistic beneficial effects on the health and development of a pediatric subject. The disclosure further relates to methods comprising the administration of said milk-based nutritional compositions to pediatric subjects. |
US08968719B2 |
Live, oral vaccine for protection against Shigella dysenteriae serotype 1
The invention relates to Salmonella typhi Ty21a comprising core-linked Shigella dysenteriae serotype 1 O-specific polysaccharide (O-Ps) and DNA encoding O antigen biosynthesis, said DNA selected from the group consisting of: a) the DNA sequence set out in any one of SEQ ID NOs: 1 and 2 and species homologs thereof; b) DNA encoding Shigella dysenteriae serotype 1 polypeptides encoded by any one of SEQ ID NOs: 1 and 2, and species homologs thereof; and c) DNA encoding a O antigen biosynthesis gene product that hybridizes under moderately stringent conditions to the DNA of (a) or (b); and related sequences, compositions of matter, vaccines, methods of using, and methods of making. |
US08968715B2 |
Drug delivery systems for photodynamic therapy
The invention is generally related to the field of photodynamic therapy by use of photosensitizers and stabilized formulations of the photosensitizers. These formulations may be used to deliver a photosensitizer as a pharmaceutical, agricultural, or industrial agent. The photosensitizer containing formulations and compositions of the invention comprise one or more block copolymers. Furthermore, the invention relates to processes for the production of, and application of, said formulations and compositions as photosensitizer drug delivery systems. |
US08968714B2 |
Carrier nanoparticles and related compositions, methods and systems
Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems. |
US08968710B1 |
Topical anesthetic
A topical anesthetic is provided containing about 3 wt % to 10 wt % tetracaine in a vehicle suitable for administration to the skin or mucosa. The vehicle for transporting the tetracaine includes a water soluble mucoadhesive or a combination of mucoadhesives such as a high molecular weight poly(ethylene oxide) homopolymer and a cellulose polymer. The vehicle also includes propylene glycol. The tetracaine is ground into a powder and is suspended in a plasticized hydrocarbon gel which completes the vehicle. |
US08968707B2 |
Composition packaged in an aerosol device, comprising at least one anionic fixing polymer, at least one silicone oxyalkylenated in the alpha and omega positions of the silicone chain, and at least one propellant
The present disclosure is directed to a composition packaged in an aerosol device comprising at least one anionic fixing polymer, at least one α and ω oxyalkylenated silicone and at least one propellant, and also to a cosmetic hair treatment process using such compositions and to a process of styling the hair using such a composition. |
US08968701B2 |
Usage of low to medium-pressure liquid chromatography for the purification of radiotracers
The invention relates to a process for the production of radiotracers. In particular, this invention relates the isolation of radiotracers with containers filled with a stationary phase. |
US08968700B2 |
Imaging of protease activity in live cells using activity based probes
Methods and materials for the imaging of cells containing active proteases such as cathepsin are disclosed. The present materials include activity based probes that bind to an enzyme and are subsequently cleaved. Cleavage results in a fluorescent signal due to removal of a quenching group which, when present on the probe causes altered or no fluorescence. The probes employ an acyloxymethyl ketone reactive group, one or more amino acids for determining specificity, a fluorophore and a quencher. The probes are cell permeable and may use, for example, a QSY7 (diarylyrhodamine) quencher and a BODIPY (bora-diaza-indecene) dye. |
US08968699B2 |
Switchable nano-vehicle delivery systems, and methods for making and using them
The invention provides nanodevices or products of manufacture for use as drug delivery vehicles. In one aspect, the invention provides nanodevices or products of manufacture having on-off release mechanisms, e.g., that are “switchable”, or “actuatable” (for example magnetically or ultrasonically switchable), for compounds contained within, e.g., for use as drug delivery nano-vehicles having on-off drug release mechanisms, and their therapeutic applications. |
US08968692B2 |
Regenerable removal of sulfur from gaseous or liquid mixtures
The present invention relates to a method for removing sulfur from a gaseous or liquid mixture. This method involves contacting the gaseous or liquid mixture with an iron-enriched matrix under conditions effective to remove sulfur from the mixture through adsorption of the sulfur to the matrix. The iron-enriched matrix used in this method is a lignocellulosic material that is enriched with iron. The present invention also relates to a system, composition, and plant fertilizer that contain the iron-enriched matrix. Methods of making the composition and preparing a plant fertilizer are also disclosed. |
US08968689B2 |
Method for recovering potassium sulphate from biodiesel production
A method is disclosed for treating residues from biodiesel production for the isolation of highly pure potassium sulphate from potassium sulphate-containing sludge. First, potassium sulphate-containing sludge from biodiesel production is heated in the first stage under non-oxidizing conditions to a material temperature between 400 and 700° C.; in a second stage the product from the first stage is heated under oxidizing conditions to material temperatures between 700 and 900° C. |
US08968686B2 |
Oxidation system with sidedraw secondary reactor
Disclosed are process and apparatus for vertical splitting of the oxygen supply to a post-oxidation reactor. Further disclosed are process and apparatus for supplying reaction medium to a post-oxidation reactor at a mid-level inlet. Such apparatus and process can assist in reducing oxygen pinch throughout the post-oxidation reactor. |
US08968685B2 |
Fuel processing system and related methods
A fuel processing system for converting a logistical fuel and air into a liquid product comprising methanol. One such system comprises a fuel injection system configured to combine a logistical fuel and ambient air to produce a logistical fuel and air mixture, a synthesis gas production system configured to convert the logistical fuel and air mixture to synthesis gas, and a methanol synthesis system configured to convert the synthesis gas to a crude methanol liquid. Related methods are additionally disclosed. |
US08968683B2 |
Tissue sample handling apparatus
The invention relates to a tissue sample handling apparatus, in particular for grasping histological samples after infiltration of an embedding medium such as, for example, paraffin, which is characterized in that a sample is immobilizable on the handling apparatus, in particular in a sample holding position, by means of negative pressure. |
US08968679B2 |
Receiver plate with multiple cross-sections
A multi-well assembly including a filter plate and receiver plate. Each plate includes a plurality of wells, which, when the filter plate is placed in nesting relationship with the receiver plate, each filter plate well has a corresponding receiver plate well into which it extends. The receiver plate wells are of a non-uniform cross-section in order to increase the gap between the outer walls of the filter plate wells and the inner walls of a corresponding receiver plate well when the receiver plate and filter plate are in nesting relationship. The increased gap size reduces wicking and cross-contamination. A multi-section well of maximum cross-section in an upper region and a minimized cross-section in a lower region, with a gradual transition between the regions, is thus provided. The multi-well assembly of the present invention also improves the repeatability of positioning the filter plate and receiver plate in proper nesting relationship and provides stability during handling, mixing and shaking operations. |
US08968678B2 |
Microfluidic detection of analytes
An apparatus and methods for concentrating samples for application to microfluidic devices are disclosed. The methods involve electrophoresing charged molecules from a high volume sample into a smaller volume. The analyte of interest can be a charged molecule or can be modified to be charged using, for example, one or more ionic moieties. |
US08968676B2 |
Method of measuring an analyte concentration in a sample of a body liquid
A hand-held device for measuring an analyte concentration in a sample of a body liquid includes a display means for displaying measured values; a measured-value storage for storing measured values; a measuring unit for generating measured values through measurements of the analyte concentration; a clock; a control unit for generating measured value datasets, each containing a measured value supplied by the measuring unit as well as the date and hour of the measurement by which the measured value was obtained, and for writing them into the measured-value storage; and operating elements that can be actuated by the user to set the clock, in which case the control unit will generate a time-correction dataset indicating the amount and direction of the setting effected. The control unit writes time-correction datasets into the measured-value storage so that a chronologically ordered sequence is generated containing time-correction datasets and measured value datasets. |
US08968675B2 |
Sample processing system
In accordance with an embodiment of a system for handling and processing chemical and/or biological samples, a MicroChamber comprises a substrate, a reservoir formed on the substrate for receiving a chemical and/or biological sample, and an encoder such as a barcode or other suitable device. The encoder encodes information describing at least one characteristic of the substrate and/or reservoir. |
US08968674B2 |
Fluid sensor preventing generation of air bubbles
Provided herein is a fluid sensor, which includes a closed reaction unit in which reaction of a fluid sample takes place. The reaction unit is tapered on a side through which the fluid is injected so as to prevent generation of air bubbles during the injection of the fluid. Thus, the sensor has improved sensitivity. |
US08968668B2 |
Arrays of metal and metal oxide microplasma devices with defect free oxide
A microplasma device of the invention includes a microcavity or microchannel defined at least partially within a thick metal oxide layer consisting essentially of defect free oxide. Electrodes are arranged with respect to the microcavity or microchannel to stimulate plasma generation in said microcavity or microchannel upon application of suitable voltage and at least one of the electrodes is encapsulated within the thick metal oxide layer. Large arrays can be formed and are highly robust as lack of microcracks in the oxide avoid dielectric breakdown. |
US08968663B2 |
Monitoring membrane-bound proteins
An apparatus for examining membrane-bound proteins in a cell can include a chamber with an insulating partition dividing the chamber into an upper well and a lower well, and a pore penetrating the insulating partition. The pore can have a size and shape so as to snugly hold a cell in place therein. The apparatus can further include circuitry for delivering a radio frequency signal to the cell. A belt electrode for delivering electrical signals to the cell can be located within the insulation partition and substantially encircling the pore. A measuring circuit for measuring cell membrane impedance to the radio frequency signal is also provided, and changes in the impedance can signal a change in state of a protein in the cell membrane. |
US08968662B2 |
Time temperature indicator
The present invention is generally in the field of measuring and indicating techniques and relates to a time-temperature indicator and methods of manufacturing and use thereof. More specifically, the time-temperature indicator comprises at least one metal layer or metal containing layer, and in direct contact to the metal layer or to the metal containing layer at least one pad member affixed onto a pad carrier layer,wherein the pad member comprises a pad made of an absorbent material and a dopant medium, whereby the dopant medium comprises a liquid medium or a viscous medium or a viscoelastic medium which is doped with a dopant that destroys the metal/metal containing layers such as an acid, a base or a salt or a photolatent acid or a photolatent base. |
US08968660B2 |
Chemical analyzer
A chemical analyzer analyzes a sample for a target chemical. The sample and reagent are added to a measurement cell until a detectable change is observed. A reference compound, which does not take part in the reaction between the target chemical and reagent, is added to the reagent. By measuring the concentration of the reference compound, the amount of reagent used may be determined. In one embodiment, a mechanism introduces the sample, adds reagent, mixes, cleans, and flushes the measurement cell, which incorporates a longitudinal chamber having inlets for the sample and reagent and an outlet for measured sample/reagent mixtures. A detector located in or adjacent to the chamber between the inlets and outlet and a piston movable in the chamber carries seals such that movement of a piston sequentially opens the inlets and expels the fluid. The analyzer also includes a device that delivers reagent to a measurement cell. |
US08968657B2 |
Transport and handling retention member
The transport and handling retention member comprises an adapter ring which has a central opening for receiving a tubular container for receiving samples, a gripping member for gripping the adapter ring, and a transfer head which can be moved between a rest position and an operating position, the transfer head in the operating position coming into operational contact with a tubular container which is received in the adapter ring. |
US08968652B2 |
Oxygenator
An oxygenator that inhibits or prevents bubbles in blood from exiting through a blood outlet includes an oxygenator part which performs gas exchange on blood and a heat exchanging part which performs heat exchange on the blood. The oxygenators part has a housing that is generally in a rectangular parallelepiped form, with a hollow fiber membrane bundle positioned in the housing. The hollow fiber membrane bundle is formed by a multiplicity of hollow fiber membranes adapted to perform gas exchange. Blood flows along a blood passage comprised of gaps between the hollow fiber membranes and contacts the surface of the hollow fiber membranes where gas exchange occurs with gas flowing through the lumens of the hollow fiber membranes. In addition, a filter member is arranged on a downstream side of the hollow fiber membrane bundle so that bubbles present in the blood are caught by the filter member. |
US08968644B2 |
NdNi5 alloys for hydrogen storage and Ni-MH batteries
A hydrogen storage alloy having the atomic formula AB4.75-5.25. Where A may comprise at least 85 atomic percent Nd and less than 15 atomic percent other rare earth elements and Mg and B may comprise Ni, Co, and at least one element selected from the group consisting of Mn and Al. The atomic percentages of Mn and Al may be governed by the following formulas where Mn and Al are in atomic percent: 1) Mn+1.5 Al≧6 atomic percent; and 2) Mn+Al≦12 atomic percent. The total percent of Mn and Al may provide the alloy with a 20° C. plateau pressure of between 4 and 25 psi, preferably between 6 and 20 psi. The hydrogen storage alloy allows a nickel metal hydride battery into which it is incorporated to maintain a voltage of at least 1.2 V at a depth of discharge of 90%. |
US08968642B2 |
Cermet body and a method of making a cermet body
A TiC-based cermet body includes TiC and WC so that the atomic ratio Ti/W is between 2 to 5, and cobalt as the binder phase is present in an amount of between 5 to 25 vol %. Further, the cermet body has at least one element from group V of the periodic table, Mx, so that the atomic ratio Ti/Mx is between 4 to 20 and the atomic ratio W/Mx is between 1 to 6. The cermet body also has Cr in an amount such that the atomic Cr/Co ratio is from 0.025 to 0.14. The cermet body includes both undissolved TiC cores with a rim of (Ti,W,Mx)C alloy as well as (Ti,W,Mx)C grains which have been formed during sintering. A method of making a cermet body is also disclosed. |
US08968638B2 |
Apparatus for injecting slurry and method therefor
The apparatus for injecting slurry contains the first member having the cavity therein; and the second member having a plurality of convex sections, each of the convex sections having the injection hole formed therein communicating with the cavity, wherein the protrusion length of the convex section is in a range from 3 to 5 mm, and the distance between centers of adjacent convex sections is in a range from 3 to 13 mm. |
US08968635B2 |
Preform for large container, large container, and method for producing large container
A preform 20 for a large container, used for producing a large container which is made of a polyethylene terephthalate resin and which is formed by stretch blow molding, is formed by injecting molding to have a wall thickness of 6 mm to 9 mm and have a longitudinal axis length longer than that of the large container which is a final molded product. |
US08968633B2 |
Method for manufacturing footwear last, and footwear last manufactured by the method
Provided is a footwear last, being of a structure where its interior is hollow. The method includes steps of installing a parison for manufacturing a plastic vessel between left/right molds for manufacturing the footwear last, with the left/right molds opened; injecting a last manufacturing material into a tube of the parison; blowing air while closing the left/right molds; molding the material in a temperature of about 400 C to 70° C. and under an injection pressure of about 600 kg/cm2 to 1400 kg/cm2; and completing the last whose interior is hollow. |
US08968628B2 |
Methods for making oxidation resistant polymeric material
The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein. |
US08968625B2 |
Process for building three-dimensional objects
A process for building three-dimensional objects based on electrophotographic printing is disclosed, comprising the steps of depositing a first layer of powdered base material on a substrate, operating an imaging member, a charging device, an image generating device and an image developing device, in that order, to deliver and deposit filler material onto the layer of powdered base material in an image-wise manner to produce a layer of bonded base material that correspond to the first cross-section of the three-dimensional object being built, repeating all the above steps for as many times as required to form successive layers that constitute the three-dimensional object, said filler material further causing adjacent layers to be bonded with one another; and removing unbonded material to cause the three-dimensional object to appear. |
US08968624B2 |
Method for producing a three dimensional green article
A method for producing a three dimensional green article includes: (a) providing a slurry composition that contains an inorganic powder, a binder, and a solvent; (b) forming a slurry layer made of the slurry composition; (c) removing the solvent of the slurry layer from an upper surface of the slurry layer so as to form the slurry layer into a green layer with a plurality of pores; (d) scanning the green layer with an energy beam having a power sufficient to vaporize or burn the binder such that the vaporized binder or the burnt binder escapes from the green layer through the pores, while leaving the inorganic powder which is not bound by the binder; and (e) repeating steps (b) to (d). |
US08968621B2 |
Method and apparatus for producing a multilayer cementitious product
Gypsum plasterboard is produced by combining calcium sulphate hemihydrate (stucco) with water to form an aqueous slurry. Uncalcined gypsum having a specific surface area below 0.3 m2/g is added to the slurry and the slurry is discharged onto a support so as to form a sheet of gypsum plasterboard. |
US08968620B2 |
Safe separation for nano imprinting
Control of lateral strain and lateral strain ratio (dt/db) between template and substrate through the selection of template and/or substrate thicknesses (Tt and/or Tb), control of template and/or substrate back pressure (Pt and/or Pb), and/or selection of material stiffness are described. |
US08968618B2 |
In-mold label forming surfaces for molded articles
A method of making a molded article having a curved surface, such as plates or serving trays, and the resulting molded articles. The in-mold label (IML) is a laminated film that includes a backing layer, a printed surface incorporating one or more designs thereon, a protective film layer, and one or more notches each having adjacent edges separated by a gap of predetermined distance and configured to intersect to ensure conformance of the IML to the angled or curved peripheral portion of the article. The article has front and back sides and a central portion bounded by a peripheral portion having a perimeter that is raised on the front side of the article wherein the peripheral portion transitions from the perimeter to the central portion by an angled surface, a curved surface or combinations thereof, with the article including the IML at least peripheral portion of the molded article. |
US08968617B2 |
Thermo-rheological fluid valve for resin infusion
A resin flow-controlling apparatus for infusing composite reinforcement material with resin. The resin flow-controlling apparatus may have at least one viscosity valve to speed, slow, allow, or deny resin flow through the viscosity valve to the composite reinforcement material depending on the temperature of the viscosity valve. The viscosity valve may fluidly couple a resin reservoir with an enclosed chamber in which the composite reinforcement material resides. The viscosity valve may be thermally coupled with heating and/or cooling elements selectively variable between at least two different temperatures to affect viscosity of the resin and control resin flow from the resin reservoir into the composite reinforcement material. A vacuum port at an opposite end of the composite reinforcement material from the viscosity valve may fluidly couple with the enclosed chamber and a vacuum source may pull atmosphere and/or resin from the enclosed chamber and/or the resin reservoir. |
US08968613B2 |
Method of making an earplug
A method of making personal protective equipment, such as a push-in earplug, is disclosed. The method includes the steps of covering a substrate with an outer layer that includes an unactivated foaming agent, positioning at least a portion of the outer layer in a mold, and activating the foaming agent such that a portion of the outer layer expands. |
US08968611B2 |
Process for solidification of phosphoric ester-based flame retardants
The present invention provides a process of solidifying a phosphoric ester-based flame retardant in which high-level purification is not required and stress load is not employed.In the process of solidifying a phosphoric ester-based flame retardant, a seed crystal is added at a temperature of not higher than 55° C. and at an amount of 1 to 50 parts by mass with respect to 100 parts by mass of a phosphoric ester compound in a molten state, which compound is represented by the following Formula (I): (wherein, R1 and R2 each independently represent a hydrogen atom or a methyl group; and n represents a number of 1 to 5). It is preferred that the amount of the phosphoric ester compound represented by the aforementioned Formula (I) wherein n is 1 be less than 90% by mass and that R1 and R2 be a hydrogen atom. |
US08968610B2 |
Polymer composition having heat-absorbing properties and high stability to weathering
The invention relates to a polymer composition which absorbs infrared radiation (IR), containing a transparent thermoplastic plastic, an inorganic infrared absorber, also referred to as IR absorber hereinbelow, at least one inorganic nano-scale pigment, and the combination of at least two organic coloring agents of a specific structure, and to the preparation and use of the polymer compositions according to the invention and to products produced therefrom. |
US08968605B2 |
Conductive polymer composition for PTC element with decreased NTC characteristics, using carbon nanotube
The present invention relates to a conductive polymer composition for a PTC element with decreased NTC characteristics, using carbon nanotubes, a PTC binder resin, and a cellulose-based or polyester-based resin for fixing the carbon nanotubes and the PTC binder, and to a PTC element, a circuit and a sheet heating element using the same. |
US08968600B2 |
Light emitting composite with phosphor components
Disclosed herein are phosphor compositions having high gadolinium concentrations. Some embodiments include a thermally stable ceramic body comprising an emissive layer, wherein said emissive layer comprises a compound represented by the formula (A1-x-zGdxDz)3B5O12, wherein: D is a first dopant selected from the group consisting of Nd, Er, Eu, Mn, Cr, Yb, Sm, Tb, Ce, Pr, Dy, Ho, Lu and combinations thereof; A is selected from the group consisting of Y, Lu, Ca, La, Tb, and combinations thereof; B is selected from the group consisting of Al, Mg, Si, Ga, In, and combinations thereof; x is in the range of about 0.20 to about 0.80; and z is in the range of about 0.001 to about 0.10. Also disclosed are thermally stable ceramic bodies that can include the composition of formula I. Methods of making the ceramic body and a lighting device including the ceramic body are also disclosed. |
US08968599B2 |
Glassy cholesteric liquid crystalline metal acetylides
A cholesteric liquid crystal. The liquid crystal includes a metal acetylide, of which the metal is a square, planar transition metal. The metal acetylide includes first and second acylphosphine ligands and first and second phenyl acetylene ligands. Each of the first and second phenyl acetylene ligands have a meta- or para-substituent, which are selected from the group consisting of H, F, CN, OCH3, C≡C—C6H5,(COO—C34H50O2), and COO—C5H10—C))—C34H50O2. |
US08968598B2 |
Liquid crystal composition and liquid crystal display device
A liquid crystal composition satisfying at least one of characteristics such as a high maximum temperature of a nematic phase, a low minimum temperature of the nematic phase, a small viscosity, a suitable optical anisotropy, a large dielectric anisotropy, a large specific resistance, a high stability to ultraviolet light and a high stability to heat, or having a suitable balance regarding at least two of the characteristics is provided; and an AM device having a short response time, a suitable pretilt, a large voltage holding ratio, a large contrast ratio, a long service life and so forth is provided. A solution is a liquid crystal composition containing a specific compound having a high maximum temperature and a large dielectric anisotropy as a first component and a polymerizable compound as a second component, and a liquid crystal display device including the composition. |
US08968597B2 |
Liquid crystal composition and liquid crystal display device
A liquid crystal composition that satisfies at least one of characteristics such as a high maximum temperature of a nematic phase, a low minimum temperature of a nematic phase, a small viscosity, a suitable optical anisotropy, a large negative dielectric anisotropy, a large specific resistance, a high stability to ultraviolet light and a high stability to heat or that is suitably balanced between at least two of the characteristics, is described. The liquid crystal composition includes a compound having three or more polymerizable groups as a first component and a compound having one or two polymerizable groups as a second component in a suitable ratio, and that may include a specific compound having a large negative dielectric anisotropy and a low minimum temperature as a third component or a specific compound having a small viscosity or a high maximum temperature as a fourth component. |
US08968596B2 |
Liquid crystal reactive monomer and liquid crystal panel
The present invention provides a liquid crystal reactive monomer on a polyimide surface of an alignment film and a liquid crystal panel. The liquid crystal reactive monomer has a hard core and is contained in a liquid crystal composition. The liquid crystal reactive monomer is represented by the formula (I) or the formula (II), and the molecular weight thereof is greater than or equal to 300. The solubility of the liquid crystal RMs is significantly improved in a liquid crystal matrix while the returning force of liquid crystal molecules is increased, so as to solve the image sticking issue, increase the polymerization capacity of the liquid crystal molecules, raise the curing speed of the curing reaction between the liquid crystal RMs and the polyimide surface and shorten the curing time, so that the purpose of energy saving and carbon reduction can be achieved. |
US08968593B2 |
Product and method for enhancing the biophysical effects of water
A product-by-process produces a product having a vibrational frequency to balance the chemistry of water when untreated water is exposed to the product to thereby enhance the biophysical properties of water, without adding any compound to the water. The result of the exposure is that the physical properties of specific gravity, conductivity, and resistivity of water are modified, and the biophysical properties of the treated water in organisms such as humans, including but not limited to hydration, oxygenation, and detoxification, are enhanced as verified by human clinical tests. |
US08968590B2 |
Cobalt carbide-based nanoparticle permanent magnet materials
A composition of a crystalline ferromagnetic material based upon nanoscale cobalt carbide particles and to a method of manufacturing the ferromagnetic material of the invention via a polyol reaction are disclosed. The crystalline ferromagnetic cobalt carbide nanoparticles of the invention are useful for high performance permanent magnet applications. The processes according to the invention are extendable to other carbide phases, for example to Fe-, FeCo-carbides. Fe- and FeCo-carbides are realizable by using as precursor salts Fe-, Co-, and mixtures of Fe- and Co-salts, such as acetates, nitrates, chlorides, bromides, citrates, and sulfates, among others. The materials according to the invention include mixtures and/or admixtures of cobalt carbides, as both Co2C and Co3C phases. Mixtures may take the form of a collection of independent particles of Co2C and Co3C or as a collection of particles which consist of an intimate combination of Co2C and Co3C phases within individual particles. The relative proportions of these two phases as well as the morphology of each phase contribute to their attractive permanent magnet properties, particularly at low temperatures through room temperature and up to over 400 K. |
US08968589B2 |
Filled-skutterudite composite material and method of preparing the same
A composite material comprises a filled skutterudite matrix of formula (I) IyCo4Sb12 in which (I) represents at least one of Yb, Eu, Ce, La, Nd, Ba and Sr, 0.05≦y<1; and GaSb particles within the filled skutterudite matrix, wherein the composite material comprises 0.05-5 mol % GaSb particles. Compared with conventional materials, the composite material exhibits a substantially increased Seebeck coefficient, a slightly decreased overall thermal conductivity, and a substantially increased thermoelectric performance index across the whole temperature zone from the low temperature end to the high temperature end, as well as a greatly enhanced thermoelectric efficiency. |
US08968585B2 |
Methods of fabrication of cartridges for biological analysis
Methods to fabricate reaction cartridges for biological sample preparation and analysis are disclosed. A cartridge may have a reaction chamber and openings to allow fluids to enter the chamber. The cartridge may also have handles to facilitate its use. Such cartridges may be used for polymerase chain reaction. |
US08968584B2 |
Method for manufacturing liquid ejection head
A method for manufacturing a liquid ejection head includes the steps of: disposing an etching mask layer on a substrate having a first face and a second face that is on an opposite side of the first face, the etching mask layer being disposed on the second face; forming a concave line pattern at a region of the etching mask layer other than a region where an opening for the support port is to be formed; providing an etching opening at the etching mask layer; performing anisotropic etching from a side of the second face using the etching mask layer provided with the etching opening as a mask, thus forming the supply port at the substrate; comparing the line pattern with a recess generated at the substrate, thus selecting a device chip for liquid ejection; and connecting the selected device chip to a liquid supply part. |
US08968571B2 |
Method and device for converting horizontal tanks into gas flotation separators
A gas flotation separator for use in horizontal tanks, such as those used for oil storage on board Floating Production Storage and Off-loading (FPSO) vessels, includes dividing the tank into a plurality of chambers operating in series. Prior to entering each chamber, the contaminated aqueous phase is mixed with a stream containing gas bubbles to aid in flocculation and flotation of the immiscible phase contaminant. The gas bubble recycle stream can be generated by injecting a controlled rate of a pressurized gas into a liquid stream of the clean produced water in a process external to the tank or by induction of a gas phase internal to the tank. The mixture flows into the first chamber and impinges on an angled inlet water weir. A portion of the immiscible phase and the gas phase rises to the top of the chamber while the remaining immiscible contaminants flow downward with the aqueous phase to the bottom of the chamber. The aqueous phase makes a 180° turn upward by entering a plurality of parallel flow conduits formed into the wall of the baffle that separates the each series chamber. In each parallel duct a second gas bubble stream is injected to further aid in flocculation and flotation of the immiscible contaminants. The aqueous phase remixes at the top of the second chamber where it impinges on a second angled weir. This process is repeated in each series chamber until the last chamber where the cleaned water is pumped out of the chamber via a liquid pump. Varying the rate of water removal there from controls the water level in last chamber. The flocculated and floating oil contaminant can be removed by either 1) periodic skimming into an over-flow weir by raising the water level in the chamber, or 2) a continuously rotating paddle or brush object that lifts or carries the floating oil layer away from the water surface and transfers it to a collector system. |
US08968567B2 |
Column packing material, column using the same, and method of separation using the same
Aimed at readily and exactly separate 8-hydroxy-2′-deoxyguanosine (8-OHdG) contained in a sample, a column packing material used for separating 8-OHdG, which contains a packing material composed of a material having a straight-chain hydrocarbon group having 6 or more and 30 or less carbon atoms as a functional group, and having a carbon content over the surface of carrier of 18% or less by element ratio, wherein the packing material contains 1 cumulative percent or more and 20 cumulative percent or less, on the particle-count basis, of particles having a circle-equivalent diameter, measured using a flow-type particle image analyzer, of 0.5 μm or larger and 10 μm or smaller, is used. |
US08968563B2 |
Fractionating and refining device
A fractionating and refining device includes a solution sending flow path for supplying a solution, including a fractionated target component, a gas supply flow path, a collecting vessel, a warming mechanism for warming the collecting vessel, and a probe formed by integrating tip end portions of the solution sending flow path and the gas supply flow path with each other. A lid of the vessel includes a solution inlet to which the tip end portion of the solution sending flow path is connected, gas inlets to which the tip end portion of the gas supply flow path is connected, and gas discharge ports connecting an inside and an outside of a vessel main body of the vessel. |
US08968562B2 |
Hydrophilic polymer microparticle, filler for ion exchange liquid chromatography, and method for production of filler for ion exchange liquid chromatography
The present is a hydrophilic polymer microparticle, which has a DW/DA ratio of 2.0 or less, the DW representing a particle diameter of the hydrophilic polymer microparticle dispersed in water, the DA representing a particle diameter of the hydrophilic polymer microparticle dispersed in acetone, each of the particle diameters measured by a particle size distribution analyzer after the hydrophilic polymer microparticle is dispersed in water or acetone, subjected to irradiation with ultrasonic waves for 15 minutes, and allowed to stand at a temperature of 25° C. for 240 hours for equilibration; and has a contact angle with water of 70° or less, the contact angle measured using a contact angle measurement apparatus at a temperature of 25° C. by forming a droplet of pure water on a single layer of the hydrophilic polymer microparticles arranged with no space therebetween. |
US08968561B2 |
Preparative separation/purification system
A mixed liquid passage (31) is connected to a trapping passage (22) at a point upstream of a trap column (23). A mixture of a diluting liquid and an additive agent, which are respectively drawn and sent by pumps (35) and (36), is supplied into the mixed liquid passage (31). When an eluate containing a target compound is passed through the trap column (23), the eluate is diluted with the diluting liquid and hence its elution capability decreases, so that the target compound can be easily captured in the trap column (23). Meanwhile, the solubility of the mobile phase in the eluate decreases, causing not only the target component but also foreign compounds to more easily precipitate. However, their precipitation is prevented by the effect of the additive agent. Thus, clogging of the trap column (23) or pipes is prevented. |
US08968560B2 |
Chromatography using multiple detectors
Methods and related apparatuses and mixtures are described for chromatographic analysis. The described system includes a pressurized source of a mobile phase and a flow path in fluid communication with the pressurized source such that the mobile phase flows through the flow path. The system also includes an injector in fluid communication with the flow path and downstream of the pressurized source, the injector being configured to inject a sample into the flow path. A first column located downstream of the injector, contains a stationary phase, and forms part of the flow path. A first detector is positioned to detect properties of fluid in the flow path at a location downstream of the injector and upstream from the first column. A second detector is positioned to detect properties of fluid in the flow path at a location downstream of the first column. |
US08968556B2 |
Process for extracting bitumen and drying the tailings
A process for separating bitumen from bitumen ore material includes extracting bitumen with a hydrocarbon solvent to produce a bitumen-enriched solvent phase and tailings. The tailings are dried or stripped in a dryer to remove any remaining hydrocarbon solvent. The amount of solvent discharged in the tailings may be less than 4 bbl per 1000 bbl of recovered bitumen. |
US08968555B2 |
Desulfurization of heavy hydrocarbons and conversion of resulting hydrosulfides utilizing copper sulfide
The present invention is a process for desulfurizing hydrocarbon feedstreams with alkali metal compounds and regenerating the alkali metal compounds via the use of a copper sulfide reagent. The present invention employs the use of a copper sulfide reagent to convert alkali metal hydrosulfides in the generation or regeneration of the alkali hydroxide compounds which may be utilized in a desulfurization process for hydrocarbon feedstreams. Additionally, in preferred embodiments of the processes disclosed herein, carbonates which form as byproducts of the desulfurization process, and are non-regenerable with copper sulfide, are removed from the alkali hydroxide stream. |
US08968548B2 |
Method of forming multicolor surface
A method of producing a multicolor surface is described herein. The method includes the following steps: providing an aluminum-based substrate having an outer and inner surfaces; performing a mechanical process on the substrate; forming at least one fixing portion on the inner surface of the substrate; forming at least one conductive hole on the fixing portion; performing a first anodization on the substrate to form a first oxide layer that can be dyed with a first color on the outer surface of the substrate; removing at least some of the first oxide layer from the fixing portion and the outer surface of the substrate; performing a second anodization on the substrate to form a second oxide layer that can be dyed with a second color on the exposed outer surface of the substrate stripped of the first oxide layer; and removing the fixing portion. |
US08968546B2 |
Capacitive deionization cell with radial flow
A water treatment apparatus comprising a stack of circular electrodes with a central through hole, the electrodes are supplied with electricity so as to form anodes and cathodes in alternating intercalation. The anodes and cathodes so arranged to lie in such close-spaced parallel face to face relationship as to form a capacitive deionization cell. Water to be treated is passed from the outside of the stack, radially inward through between the electrodes into the central through hole and then axially out of the stack. |
US08968539B2 |
Methods for voltage-induced protein incorporation into planar lipid bilayers
Disclosed here are methods useful for incorporating protein into lipid bilayers using voltage induced insertion. The methods presented herein can decrease time and costs associated with incorporation of proteins into naturally derived or artificially created lipid bilayers. A method for incorporating a protein capable of translocating a ligand also is disclosed herein. |
US08968533B2 |
Electroplating processor with geometric electrolyte flow path
An electroplating processor includes an electrode plate having a continuous flow path formed in a channel. The flow path may optionally be a coiled flow path. One or more electrodes are positioned in the channel. A membrane plate is attached to the electrode plate with a membrane in between them. Electrolyte moves through the flow path at a high velocity, preventing bubbles from sticking to the bottom surface of membrane. Any bubbles in the flow path are entrained in the fast moving electrolyte and carried away from the membrane. The electroplating processor may alternatively have a wire electrode extending through a tubular membrane formed into a coil or other shape, optionally including shapes having straight segments. |
US08968532B2 |
Electrochemical processor alignment system
A substrate plating processor has a vessel on a support structure and a head support fixed in place relative to the support structure. A head having a rotor is attached to the head support. A lifter associated with the head support moves the head into and out of engagement with the vessel. An alignment assembly attachable to the rotor has at least one sensor adapted to detect a position of an inside surface of the vessel when the head is engaged with the vessel. The sensor may be a physical contact sensor positioned to contact the inside surface of the vessel. |
US08968531B2 |
Electro processor with shielded contact ring
In an electro processor for plating semiconductor wafers and similar substrates, a contact ring has a plurality of spaced apart contact fingers. A shield at least partially overlies the contact fingers. The shield changes the electric field around the outer edge of the workpiece and the contact fingers, which reduces or eliminates the negative aspects of using high thief electrode currents and seed layer deplating. The shield may be provided in the form of an annular ring substantially completely overlying and covering, and optionally touching the contact fingers. |
US08968529B2 |
Production method for forming an antibacterial film on the surface of an object
A production method combining cathode arc and magnetron sputtering methods to form an antibacterial film on the surface of an object. Inside the vacuum chamber, both a cathode arc target source and a magnetron sputtering target source are configured. On the cathode arc target source, at least one of a zirconium, titanium, or chromium target is installed. On the magnetron sputtering target source, a silver target is installed. Argon and nitrogen are filled into the vacuum chamber to respectively ionize the silver target and one of the zirconium target, titanium target, or chromium target. Remote control is used to adjust the ionization proportion between one of the zirconium, titanium, or chromium target and the silver target to be 90-99%:1-9%. The surface of the object is formed with one of the zirconium nitride-silver mixed antibacterial film, titanium nitride-silver mixed antibacterial film, or chromium nitride-silver mixed antibacterial film. |
US08968528B2 |
Platinum-modified cathodic arc coating
A process for coating a part comprises the steps of providing a chamber which is electrically connected as an anode, placing the part to be coated in the chamber, providing a cathode formed from a coating material to be deposited and platinum, and applying a current to the anode and the cathode to deposit the coating material and the platinum on the part. |
US08968525B2 |
Methods of flash reduction and patterning of graphite oxide and its polymer composites
A method of reducing a film of graphite oxide. In one embodiment, the method includes the steps of providing a film of graphite oxide with a thickness d0; and delivering optical energy in a single pulse to the film of graphite oxide at a distance no more than 1.0 cm away from the film of graphite oxide to reduce the film of graphite oxide to a film of graphene with a thickness d, wherein the optical energy has a radiant exposure in the range of between 0.1 and 2 J/cm2, and wherein the thickness d is greater than the thickness d0. In one embodiment, the thickness d≧10×d0. |
US08968524B2 |
Method for fabricating divided wall columns
The invention relates to a method producing a portioned column by forming a first segment and a third segment into arcuate segments, and attaching these arcuate segments to a second z-shaped segment to from two contiguous volumes with approximately semi-circular cross-sections that combine to form a partitioned, approximately cylindrical segment. |
US08968523B2 |
Recovery of butanol isomers from a mixture of butanol isomers, water, and an organic extractant
A process for recovering butanol from a mixture of a water-immiscible organic extractant, water, butanol, and optionally a non-condensable gas, is provided. The butanol is selected from 1-butanol, isobutanol, and mixtures thereof. An overhead stream from a first distillation column is decanted into two liquid phases. The wet butanol phase is refined in a second distillation column; the aqueous phase is returned to the first distillation column. A portion of the wet butanol phase from the decanter is also returned to the first distillation column. The extractant may be C7 to C22 fatty alcohols, C7 to C22 fatty acids, esters of C7 to C22 fatty acids, C7 to C22 fatty aldehydes, and mixtures thereof. |
US08968516B2 |
Methods of making a belt-creped absorbent cellulosic sheet prepared with a perforated polymeric belt
A method of making a belt-creped absorbent cellulosic sheet that has an upper surface and a lower surface. A papermaking furnish is compactively dewatered to form a dewatered web having an apparently random distribution of papermaking fiber orientation. The dewatered web is applied to a translating transfer surface. The web is belt creped from the transfer surface at a consistency of from about 30% to about 60% utilizing a generally planar polymeric creping belt having a plurality of perforations. The belt-creping step occurs under pressure in a belt creping nip defined between the transfer surface and the creping belt. The belt is traveling at a belt speed that is slower than the speed of the transfer surface, and the web is creped from the transfer surface and redistributed on the creping belt to form a web. |
US08968513B2 |
Plasma processing apparatus
An intensity distribution of an electric field of a high frequency power used for generating plasma is controlled by using an electrode made of a homogeneous material and a moving body. There is provided a plasma processing apparatus for introducing a processing gas into an evacuable processing chamber 100 and generating plasma by a high frequency power and performing a plasma process on a wafer W by the plasma. The plasma processing apparatus includes a dielectric base 105a having a multiple number of fine holes A; a varying member 200 as the moving body provided with a multiple number of rod-shaped members B capable of being inserted into and separated from the fine holes A; and a driving mechanism 215 configured to drive the varying member 200 to allow the rod-shaped members B to be inserted into and separated from the fine holes A. |
US08968511B2 |
Medical device and technique for using the same
An inflatable balloon cuff may be adapted to seal a patient's trachea when associated with an endotracheal tube. These cuffs may include indicia that facilitate attachment of the cuff relative to the tube to reduce manufacturing variability for such characteristics as rotational and length alignment. Such indicia may include protrusions that are formed in the wall of the cuff collars or may include visual indicators, e.g., colorimetric or shape-wise indicators. Cuffs with improved attachment relative to the tube may have increased sealing performance. |
US08968508B2 |
Joining polymeric materials
Systems and methods for joining polymeric materials together may use lasers or broadband infrared heat sources. The polymeric materials are arranged in an overlapping manner and then are exposed to the heat producing radiation for a sufficient time to join the polymeric materials together at the overlapped area. Such systems and methods may avoid the need to add an energy absorbing dopant to the materials being joined. Such systems and methods also may be used on transparent materials. |
US08968503B2 |
Electrostatic chucks and methods for refurbishing same
Novel methods for extending electrostatic chuck lifetimes are provided. The methods involve providing a chuck having a metal cooling plate attached to a ceramic top plate, and after a period of use, disassembling the chuck, and providing a new chuck including the used metal cooling plate. In certain embodiments, the use of a low temperature bond material uniquely allows the described disassembly and reassembly without damage to other parts of the chuck. |
US08968496B2 |
Method of press hardening a steel sheet blank
In a press-hardening plant, a contact-cooling press (12) is provided between the furnace (11) and the press-hardening press (13). Preselected parts of the blank (18) are contact-cooled such that corresponding parts of the finished product are softer and display a lower yield point. |
US08968493B2 |
Gas generator case repair
A method of reforming an annular attachment flange of an outer annular portion of a gas generator case, including inserting a first fixture element within the annular portion, the first fixture element conforming to an inner surface of the flange and forcing the flange radially outwardly passed a desired orientation, pressing the attachment flange against the first fixture element with a second annular fixture element surrounding the flange and conforming to an outer surface of the flange, heating the outer portion pressed by the fixture elements to a temperature and time period corresponding to an annealing of the material of the outer portion, forcing cooling of the outer portion, and disengaging the cooled outer portion from the fixture elements so that the released flange extends at the desired orientation. A gas generator case including a reformed outer portion and an unused inner portion is also discussed. |
US08968491B2 |
Sputtering target and method for producing same
[Problems to be Solved]To provide a sputtering target that is capable of forming a Cu—Ga film to which Na is favorably added by a sputtering method, and a method for producing the same.[Means to Solve the Problems]The sputtering target is provided wherein 20 to 40 at % of Ga, 0.05 to 2 at % of Na, and 0.025 to 1.0 at % of S are contained and a remaining portion has a component composition consisting of Cu and unavoidable impurities. Also, a method for producing the sputtering target includes the step of hot pressing a mixed powder of Na2S powder and Cu—Ga alloy powder or a mixed powder of Na2S powder, Cu—Ga alloy powder, and pure Cu powder in a vacuum atmosphere or an inert gas atmosphere or sintering a mixed powder of Na2S powder and Cu—Ga alloy powder or a mixed powder of Na2S powder, Cu—Ga alloy powder, and pure Cu powder by hot isostatic pressing. |
US08968489B2 |
Ferromagnetic amorphous alloy ribbon with reduced surface defects and application thereof
A ferromagnetic amorphous alloy ribbon, a method of fabricating a ribbon and a wound transformer core are provided. The ribbon includes an alloy of FeaSibBcCd where 80.5≦a≦83 at. %, 0.5≦b≦6 at. %, 12≦c≦16.5 at. %, 0.01≦d≦1 at. % with a+b+c+d=100, and is cast from a molten state of the alloy, having a-surface tension of greater than or equal to 1.1 N/mi,. A defect length along a direction of the ribbon's length is between 5 mm and 200 mm, a defect depth less than 0.4 ×t μm and a defect occurrence frequency less than 0.05 ×w times within 1.5 m of ribbon length, where t is the ribbon thickness and w is the ribbon width in mm. The ribbon has a saturation magnetic induction exceeding 1.60 T and a magnetic core loss of less than 0.14 W/kg when measured at 60 Hz and at 1.3 T induction level in an annealed straight strip form, and a core magnetic loss of less than 0.3 W/kg and an exciting power of less than 0.4 VA/kg in an annealed wound transformer core form and is suitable for use in transformer cores, rotational machines, electrical chokes, magnetic sensors and pulse power devices. |
US08968486B2 |
Rinse aid release detection method
A dishwashing machine configured to detect the presence of rinse aid in fluid in a washing chamber of the dishwashing machine. An electronic controller selects the drying stage of the dishwashing cycle based on whether rinse aid is present. |
US08968483B2 |
Method of using liquid in a dishwasher
A method of operating a dishwasher having a treating chamber for washing dishes includes dispensing a detergent, supplying liquid to mix with the detergent to form a wash liquid, storing a first portion of the wash liquid in a reuse tank and using a second portion of the wash liquid in the treating chamber, supplying the first portion of the wash liquid from the reuse tank to the treating chamber. |
US08968478B2 |
Pretreatment method for saccharification of plant fiber material and saccharification method
A pretreatment method for saccharification of plant fiber materials includes: immersing the plant fiber material in a solution that contains an organic solvent, in which a cluster acid is dissolved, prior to saccharifying cellulose contained in the plant fiber material; and distilling off the organic solvent from the immersed plant fiber material to obtain a pretreated mixture that contains the cluster acid and the pretreated plant fiber material. |
US08968477B2 |
Deposition mask and method for manufacturing organic light emitting display using the same
A deposition mask for manufacturing an organic light emitting display (OLED) using the same are provided. The deposition mask is intended for preventing an organic film from being damaged due to touching of a blocked-off portion of the mask to an emission layer (EML), or chemical transition from being generated at the organic film. For that purpose, the deposition mask stuck to a substrate of the OLED to deposit an organic EML includes an opening and an indentation. The opening is opened so as to deposit the organic EML. The indentation is indented a predetermined depth from a plane facing the substrate. |
US08968476B2 |
Atomic layer deposition apparatus
An atomic deposition apparatus is provided for simultaneously loading/unloading a plurality of substrates. The atomic deposition apparatus which may load/unload the plurality of substrates when transmitting the plurality of substrates to a process module, includes a loading/unloading module for loading/unloading a substrate, a process module including a plurality of process chambers for simultaneously receiving a plurality of substrates and performing a deposition process, each of the plurality of process chambers including a gas spraying unit having an exhaust portion by which an exhaust gas is drawn in from inside the process chamber and the drawn in gas is exhausted above the process chamber, and a transfer module including a transfer robot provided between the loading/unloading module and the process module, the transfer robot being adopted for simultaneously holding the plurality of substrates while transporting the substrate. |
US08968474B2 |
Substrate processing apparatus and method of disassembling and assembling the same
A substrate processing apparatus includes: a chamber including a body having an open portion and a door for blocking the open portion; a substrate supporter connected to the door; and a door operating means including a rotation shaft for straightly moving and rotating the door, the door and the body separated in parallel from each other by straightly moving the door. |
US08968469B2 |
Semiconductor device and method of manufacture thereof
A structure including a substrate, an intermediate layer provided and formed directly onto the substrate, a transition region, and a group II-VI bulk crystal material provided and formed as an extension of the transition region. The transition region acts to change the structure from the underlying substrate to that of the bulk crystal. In a method of manufacture, a similar technique can be used for growing the transition region and the bulk crystal layer. |
US08968467B2 |
Method and system for controlling resistivity in ingots made of compensated feedstock silicon
Techniques for controlling resistivity in the formation of a silicon ingot from compensated feedstock silicon material prepares a compensated, upgraded metallurgical silicon feedstock for being melted to form a silicon melt. The compensated, upgraded metallurgical silicon feedstock provides semiconductor predominantly of a single type (p-type or n-type) for which the process assesses the concentrations of boron and phosphorus and adds a predetermined amount of boron, phosphorus, aluminum and/or gallium. The process further melts the silicon feedstock with the boron, phosphorus, aluminum and/or gallium to form a molten silicon solution from which to perform directional solidification and maintains the homogeneity of the resistivity of the silicon throughout the ingot. A balanced amount of phosphorus can be optionally added to the aluminum and/or gallium. Resistivity may also be measured repeatedly during ingot formation, and additional dopant may be added in response, either repeatedly or continuously. |
US08968463B2 |
Hydrogen-trapping material, method of preparation and uses
A material capable for trapping a flammable gas such as hydrogen comprising at least one metal oxide in a cementitious matrix is disclosed. According to some aspects, the preparation of such a material and its different uses are also disclosed. |
US08968455B2 |
Dental investment material
A new investment material for the pressing loss wax technique for dental glass ceramics. It has been found that the addition of fillers to a magnesium phosphate investment, specifically metal oxides with elevated melting points ranging from 1800 to 2800° C., provides a protection barrier against the reaction between the high alkaline content of the glass ceramic and the investment during the pressing process in the range of 800 to 950° C. Specifically, it has been found that the addition of aluminum oxide of about 2 to 5 percent of the total dry mix in combination with any of the zirconium oxide, yttrium stabilized zirconium, titanium dioxide and boron nitride in proportions of about 3.5%, enhances the barrier against a surface reaction and improves the thermal properties of the investment. |
US08968454B2 |
Magenta quinacridone pigments
The invention relates to single phase solid solutions containing 65 to 98 wt.-% unsubstituted quinacridone, 1 to 34 wt.-% 2,9-dimethylquinacridone and 1 to 10 wt.-% 2,9-dichloroquinacridone, relative to the total weight of the single phase solid solution. |
US08968451B2 |
Apparatus for concentrating a solution
An apparatus for concentrating solution includes a plurality of nozzles (1) to spray solution into minute particle mist, a gas supplier (2) to transfer gas-mist mixture containing mist by supplying carrier gas to mist sprayed from the nozzle (1), and a separator (3) to separate a component with a low boiling point from a component with a high boiling point by supplying gas-mist mixture transferred using the gas supplier (2). The gas supplier (2) defines a plurality of apertures (9) to supply carrier gas to the plurality of nozzles (1). In this apparatus for concentrating solution, the plurality of nozzles (1) are spraying mist into carrier gas supplied from the apertures (9). |
US08968450B1 |
Wet scrubber design
The present invention is a wet scrubber having a forced mixing chamber on top of an immersed packed bed, significantly increasing the scrubbing efficiency of acid gases and other pollutants by maximizing gas to liquid contact. A mixing fan located outside of the wet scrubber being connected to a mixing zone through an inlet duct to receive fluid from the mixing zone and an exhaust duct to blow fluid back into the mixing zone, thereby enhancing the mixing process inside the mixing zone. |
US08968449B2 |
Spout, system, and method for producing a foam
A spout, system, and method for producing a foam from a pressurized mixture of a liquid containing gas bubbles, e.g., air bubbles. The spout consists of a spout enclosure defining the body of the spout, and which receives the pressurized mixture and conveys the foam out of the spout enclosure. The spout enclosure houses a plurality of screens disposed in series that successively screen the pressurized mixture. Each screen is separated from a consecutive screen by a screen spacing. The screening of the pressurized mixture progressively transforms the gas bubbles in the liquid into foam bubbles of a smaller and generally uniform size. The system uses a manifold having a plurality of intakes which introduce under pressure into a chamber gas, and a solute, solvent or liquid, thereby generating the pressurized mixture containing gas bubbles. This mixture is conveyed out of the chamber via an outtake to the spout enclosure. |