Document Document Title
US08895795B2 Acid washed silica supported catalysts and their use in olefin metathesis
Acid washing of silica supports, used for supported tungsten catalysts, improves the activity of the resulting catalyst (i.e., its conversion level at a given temperature) for the metathesis of olefins, without compromising its selectivity to the desired conversion product(s). Exemplary catalysts and processes include those for the production of valuable light olefins such as propylene from a hydrocarbon feedstock comprising ethylene and butylene.
US08895792B2 Process for the preparation of an olefinic product comprising ethylene and/or propylene
An oxygenate to olefins (OTO) process, comprising the steps of: (i) purifying an oxygenate feedstream comprising one or more ionic contaminants by contacting the feedstream with a membrane, resulting in the formation of a retentate and a permeate separated by the membrane, which permeate is a purified oxygenate stream which contains a lower ionic contaminant concentration than the original oxygenate feedstream; (ii) introducing the purified oxygenate stream into an oxygenate to olefins reaction zone; and (iii) contacting the purified oxygenate stream with a molecular sieve catalyst in the oxygenate to olefins reaction zone to form a product stream comprising olefins.
US08895790B2 Conversion of plastics to olefin and aromatic products
A catalyst composition useful for producing olefins and aromatic compounds from a feedstock is formed from a fluidized catalytic cracking (FCC) catalyst and a ZSM-5 zeolite catalyst, wherein the amount of ZSM-5 zeolite catalyst makes up from 10 wt. % or more by total weight of the FCC catalyst and the ZSM-5 zeolite catalyst. The catalyst composition may be used in a method of producing olefins and aromatic compounds from a feedstock by introducing a hydrocarbon feedstock and the catalyst composition within a reactor, at least a portion of the reactor being at a reactor temperature of 550° C. or higher. The feedstock and catalyst composition are introduced into the reactor at a catalyst-to-feed (C/F) ratio of from 6 or greater.
US08895789B2 Fuel composition for use in gasoline engines
A fuel composition for use in gasoline engines which has excellent acceleration characteristics at high speeds and excellent fuel consumption. The fuel composition of this invention for use in gasoline engines satisfies the conditions: (1) the research octane number is not less than 99; (2) the density is in the range of from 0.750 to 0.770 g/cm3; (3) the distillation temperature at 50 vol % distilled is in the range of from 95 to 102° C., the distillation temperature at 90 vol % distilled is in the range of from 160 to 180 ° C., and the distillation end point is in the range of from 180 to 220 ° C.; and (4) the content of aromatic hydrocarbons with 9 or more carbon atoms is in the range of from 15 to 25% by volume, and the indane content is in the range of from 0.5 to 3.0% by volume.
US08895788B2 Process for the manufacture of hydrofluoroolefins
The invention relates to a process for manufacturing 1,1,1,2-tetrafluoropropene (1234yf, CF3—CF═CH2) from 1,1,3,3-tetrachlororopropene (1230za, CCl2═CH—CHCl2) and/or 1,1,1,3,3-pentachloropropane (240fa, CCl3CH2CHCl2). The process comprises a step of isomerization of 1,1,3,3-tetrafluoropropene (1230za) to 1,1,2,3-tetrachloropropene (1230xa) followed by conversion of the 1,1,2,3-tetrachloropropene (1230xa) to 1,1,1,2-tetrafluoropropene (1234yf) via a hydrofluorination process.
US08895787B2 Compositions comprising a dehalogenase substrate and a radionuclide and methods of use
A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein.
US08895785B2 Processes for separating one or more amine byproducts from one or more desired amines
The present invention relates to separating one or more amine byproducts from one or more desired amines. More particularly, the invention involves forming a byproduct component with one or more amine byproducts and a first adjuvant component. The byproduct component has an enhanced separation characteristic relative to separating the amine byproducts from the desired amines in the absence of an adjuvant. Preferably, the byproduct component is separated in the presence of a second adjuvant component that preferably has a boiling point less than the boiling point of the first adjuvant component.
US08895783B2 Monitoring of the stoichiometric ratio in the reaction of nitroaromatics with hydrogen
The present invention relates to a continuous process for preparing at least one aromatic amine by hydrogenation of at least one nitroaromatic by means of hydrogen, where a liquid phase comprising at least the aromatic amine and a gas phase comprising at least hydrogen are present, in the presence of a catalyst suspended in the liquid phase at a temperature of from 50 to 250° C. and a pressure of from 5 to 50 bar, wherein the pressure in the reactor is kept essentially constant by continuous adaptation of the amount of hydrogen fed to the reactor, the total amount of hydrogen fed to the reactor is monitored and the introduction of the at least one nitroaromatic is interrupted if the hydrogen uptake in the reactor is not at least 50 mol % of the amount of hydrogen required for stoichiometric reaction of the at least one nitroaromatic to form the at least one aromatic amine.
US08895781B2 Transition metal-catalyzed C—H amination using unactivated amines
One aspect of the invention relates to a method of animation or amidation, comprising the step of combining a substrate, comprising a reactive C—H bond, and an amine or amide, comprising a reactive N—H bond, in the presence of an oxidizing agent and a metal-containing catalyst, thereby forming a product with a covalent bond between the carbon of the reactive C—H bond and the nitrogen of the reactive N—H bond.
US08895779B2 Processes for producing monoammonium adipate and conversion of monoammonium adipate to adipic acid
A process for making MAA from a clarified DAA-containing fermentation broth includes (a) distilling the broth to form an overhead that includes water and ammonia, and a liquid bottoms that includes MAA, at least some DAA, and at least about 20 wt. % water; (b) cooling the bottoms to a temperature sufficient to cause the bottoms to separate into a DAA-containing liquid portion in contact with a MAA-containing solid portion that is substantially free of DAA; (c) separating the solid portion from the liquid portion; and (d) recovering the solid portion.
US08895778B2 Depolymerization of polylactic acid
The invention provides energy efficient depolymerization of polyesters such as post-consumer polylactic acid. Ultrasonic induced implosions can be used to facilitate the depolymerization. The expanding market of polylactic acid-based plastic products, such as water bottles and packaging materials, has raised concerns of contaminating the recycling stream, which is largely filled with petroleum-based plastics. Thus the development of an energy efficient and economically viable PLA recycling process is urgently needed. Post consumer PLA was exposed to methanol as the suspension media in the presence of organic or ionic salts of alkali metals such a potassium carbonate and sodium hydroxide as depolymerization catalysts to provide high quality lactic acid monomers in high yield.
US08895776B2 Modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto
The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of: pulmonary arterial hypertension (PAH); idiopathic PAH; familial PAH; PAH associated with a collagen vascular disease, a congenital heart disease, portal hypertension, HIV infection, ingestion of a drug or toxin, hereditary hemorrhagic telangiectasia, splenectomy, pulmonary veno-occlusive disease (PVOD) or pulmonary capillary hemangiomatosis (PCH); PAH with significant venous or capillary involvement; platelet aggregation; coronary artery disease; myocardial infarction; transient ischemic attack; angina; stroke; ischemia-reperfusion injury; restenosis; atrial fibrillation; blood clot formation in an angioplasty or coronary bypass surgery individual or in an individual suffering from atrial fibrillation; atherosclerosis; atherothrombosis; asthma or a symptom thereof; a diabetic-related disorder such as diabetic peripheral neuropathy, diabetic nephropathy or diabetic retinopathy; glaucoma or other disease of the eye with abnormal intraocular pressure; hypertension; inflammation; psoriasis; psoriatic arthritis; rheumatoid arthritis; Crohn's disease; transplant rejection; multiple sclerosis; systemic lupus erythematosus (SLE); ulcerative colitis; ischemia-reperfusion injury; restenosis; atherosclerosis; acne; type 1 diabetes; type 2 diabetes; sepsis; and chronic obstructive pulmonary disorder (COPD).
US08895771B2 Methods of making organic compounds by metathesis and hydrocyanation
The invention is directed to methods of making organic compounds by metathesis and hydrocyanation. The method of the invention may be used, for example, to make industrial important organic compounds such as diacids, diesters, acid-amines, acid-alcohols, acid-nitriles, ester-amines, ester-alcohols, and ester-nitriles.
US08895769B2 Silicon-containing carboxylic acid derivative
A compound represented by the formula (I) [R1 to R3 represent an alkyl group, an alkenyl group, and the like; n represents 0 or 1; R4 represents an amino group or —(CX2)m—COOH (m represents 0 to 3, and X represents hydrogen atom); R5 represents —(CY2)p—COOR6 (p represents an 0 to 3, Y represents hydrogen atom, and R6 represents hydrogen atom or an alkyl group)], or a salt thereof.
US08895767B2 Obtaining fatty acids from insect larvae
Extract of oil rich in saturated, monounsaturated and polyunsaturated fatty acids containing oil extracted from insect larvae comprising saturated, MUFA and PUFA fatty acids and procedure for obtaining oil extract.
US08895766B2 Blown and stripped plant-based oils
A method for producing a high viscosity, low volatiles blown stripped plant-based oil is provided. The method may include the steps of: (i) obtaining a plant-based oil; (ii) heating the oil to at least 90C; (iii) passing air through the heated oil to produce a blown oil having a viscosity of at least 200 cSt at 40C; (iv) stripping the blown oil from step (iii) to reduce an acid value of the blown oil to from 5 mg KOH/g to about 9 mg KOH/g; (v) adding a polyol to the stripped oil from (iv); and (vi) stripping the oil from step (v) to reduce the acid value of the oil to less than 5.0 mg KOH/g or less.
US08895765B2 Method and apparatus for preparing alkyl ester fatty acid using fatty acid
A method for preparing fatty acid alkyl ester for bio-diesel fuel is disclosed wherein fatty acid, specifically fatty acid distillate reacts with alcohol. The method does not require the glycerin purification process, and has the superior conversion ratio of fatty acid. The method for preparing fatty acid alkyl ester for bio-diesel fuel comprises the step of carrying out a counter current type esterification reaction of fatty acid and alcohol in each tray of a counter current column reactor at a temperature of 200 to 350° C. and a pressure of 1 to 35 bar. Here the raw material of the fatty acid is fed to an upper part of the counter current column reactor and the alcohol is fed to a lower part of the counter current column reactor. The counter current column reactor has a number of trays which are installed horizontally to have a number of vertical compartments. Each of the number of trays has an opening part at one end thereof to communicate one compartment with an adjoining compartment. The opening parts of two adjoining trays are alternately installed with each other.
US08895764B2 ZnO nanoparticle catalysts for use in biodiesel production and method of making
A method of forming a biodiesel product and a heterogeneous catalyst system used to form said product that has a high tolerance for the presence of water and free fatty acids (FFA) in the oil feedstock is disclosed. This catalyst system may simultaneously catalyze both the esterification of FAA and the transesterification of triglycerides present in the oil feedstock. The catalyst system is comprised of a mixture of zinc oxide and a second metal oxide. The zinc oxide includes a mixture of amorphous zinc oxide and zinc oxide nanocrystals, the zinc nanocrystals having a mean grain size between about 20 and 80 nanometers with at least one of the nanocrystals including a mesopore having a diameter of about 5 to 15 nanometers. Preferably, the second metal oxide is a lanthanum oxide, the lanthanum oxide being selected as one from the group of La2CO5, LaOOH, and combinations or mixtures thereof.
US08895753B2 S1P receptor modulating agent
An object of the present invention is to provide a compound having a modulating activity at an S1P receptor which is useful for preventing and treating autoimmune diseases, allergic diseases, and the like. According to the present invention, a compound represented by formula (I) or a pharmaceutically acceptable salt thereof is provided.
US08895752B2 Alkylsulfonyl-substituted thiazolide compounds
A new class of alkylsulfonyl-substituted thiazolide compounds is described. These compounds show strong activity against hepatitis virus.
US08895751B2 Process of manufacturing benzobisthiazole building blocks for conjugated polymers
A process comprising the step of synthesizing 2,6-dibromo-4,8-dihexylbenzo[1,2-d:4,5-d′]bis(thiazole) from 2,5-dihyxylbenzene-1,4-diamine.
US08895744B2 Alfa-carboline inhibitors of NPM-ALK, RET, and Bcr-Abl
The present invention relates to compounds of formula (I) wherein R1, R2 and R3 are as defined in the description, to their pharmaceutical compositions and use thereof for the treatment of cancer expressing oncogenic ALK protein, particularly anaplastic large cell lymphoma (ALCL), diffuse large B cell lymphoma (DLBCL), inflammatory myofibroblastic tumors (IMT) and non-small cell lung cancer (NSCLC).
US08895743B2 Methysergide derivatives
Provided herein are novel methysergide derivatives and compositions thereof. In other embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders or symptoms thereof, such as, migraine and Parkinson's disease using the compounds and compositions disclosed herein. In still other embodiments, provided herein, such as, for example, are methods for antagonizing the 5-HT2B receptor without agonizing the 5-HT2B receptor using the compounds and compositions disclosed herein. In still other embodiments, provided herein such as, for example, are methods of agonizing the 5-HT1A receptor using the compounds and compositions disclosed herein.
US08895742B2 Metal-mediated reversible self-assembly of carbon nanotubes
There is provided a method and nanocomposite for the reversible assembly of nanotubes, such as oxidized single wall carbon nanotubes, based on metal coordination. The method produces a thermally stable, neutral nanocomposite possessing enhanced mechanical, electrical, physical and chemical properties for example. Disassembly can be provided by treatment with a competing ligand compound.
US08895738B2 Mesoionic pyrido [1, 2-A] pyrimidine pesticides
Disclosed are compounds of Formula 1, wherein R1 is phenyl or pyridinyl, each optionally substituted with Q and up to 3 substituents independently selected from R2; each R2 is independently halogen, cyano, SF5, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkoxy, C1-C4 haloalkoxy, C1-C4 alkylthio or C1-C4 haloalkylthio; and Q is phenyl or pyridinyl, each optionally substituted with up to 5 substituents independently selected from the group consisting of halogen, cyano, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkoxy and C1-C4 haloalkoxy. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention. Further disclosed are methods for increasing vigor of a crop plant comprising contacting the crop plant, the seed from which the crop plant is grown or the locus of the crop plant with a biologically effective amount of a compound or composition of the invention.
US08895734B2 Peptide nucleic acid derivatives with good cell penetration and strong affinity for nucleic acid
The present invention provides a novel class of peptide nucleic acid derivatives, which show good cell penetration and strong binding affinity for nucleic acid.
US08895729B2 Process for making thienopyrimidine compounds
Process methods for making the dual mTOR/PI3K inhibitor GDC-0980, named as (S)-1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one, having the structure: and stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof.
US08895726B2 Compounds derived from indole and pharmaceutical compositions containing them
The present invention relates to a compound derived from indole corresponding to the following formula II: wherein X represents N, CR8 or N+R8, wherein R8 represents a hydrogen atom, a hydroxyl or alkyl or methoxy group optionally substituted with a phenyl group; R2, R3 and R4 independently represent a hydrogen atom or a halogen atom or an optionally substituted alkyl, amine, alkene, ester, sulfonamide, ether or benzyl group; R5 represents a hydrogen atom or an optionally substituted, saturated or unsaturated alkyl group, amine, benzyl group; R6 represents an optionally substituted C1-C3 alkyl group; R7 represents a hydrogen atom or an optionally substituted C1-C3 alkyl group and R7 is absent when the ring A is in the b position, and A represents a ring; R9 and R10 represent together a carbon bond or independently represent an R11 OR11, SR11 group; wherein R11 represents a hydrogen atom, an optionally substituted, saturated or unsaturated, C1-C3 alkyl group, which may contain one or more sulfur, oxygen or nitrogen atoms; pharmaceutically acceptable salts of said compounds, their isomers and/or a mixture thereof; pharmaceutical composition comprising such a compound; the use of such a compound for preparing a drug intended to treat a genetic disease resulting from at least one mutation causing the occurrence of an early termination codon.
US08895723B2 Methods of preparing substituted nucleotide analogs
Disclosed herein are methods of preparing a phosphorothioate nucleotide analog, which are useful in treating diseases and/or conditions such as viral infections.
US08895722B2 Splice-region antisense composition and method
Antisense compositions targeted against an mRNA sequence coding for a selected protein, at a region having its 5′ end from 1 to about 25 base pairs downstream of a normal splice acceptor junction in the preprocessed mRNA, are disclosed. The antisense compound is RNase-inactive, and is preferably a phosphorodiamidate-linked morpholino oligonucleotide. Such targeting is effective to inhibit natural mRNA splice processing, produce splice variant mRNAs, and inhibit normal expression of the protein.
US08895716B2 Viral promoter, truncations thereof, and methods of use
The present disclosure provides compositions and methods for regulating expression of heterologous nucleotide sequences in a plant. Compositions include a novel nucleotide sequence for a promoter. A method for expressing a heterologous nucleotide sequence in a plant using the promoter sequence disclosed herein is provided. The method comprises stably incorporating into the genome of a plant cell a nucleotide sequence operably linked to the promoter of the present invention and regenerating a stably transformed plant that expresses the nucleotide sequence.
US08895712B2 Artificial base pair capable of forming specific base pair
The present invention provides a double-stranded nucleic acid in which at least one nucleic acid strand includes an unnatural base that forms a self-complementary base pair or an unnatural base that forms a base pair with any natural base with substantially the same thermal stability. The present invention also provides a method of hybridizing a first nucleic acid strand with a second nucleic acid strand, wherein the first nucleic acid strand includes an unnatural base that forms a self-complementary base pair or an unnatural base that forms a base pair with any natural base with substantially the same thermal stability, and a method of applying the nucleic acid to SNP detection, a DNA chip, DNA/RNA computing, or an in vitro translation system. The present invention provides a method of introducing an unnatural base into a nucleic acid strand and thereby controlling the thermodynamic stability in hybridization of the nucleic acid strand.
US08895709B2 Isolation and purification of antibodies using protein A affinity chromatography
Disclosed herein are methods for the isolation and purification of antibodies wherein the use of an affinity chromatographic step results in an antibody composition sufficiently pure for pharmaceutical uses. The methods described herein comprise pH viral reduction/inactivation, ultrafiltration/diafiltration, affinity chromatography, preferably Protein A affinity, ion exchange chromatography, and hydrophobic chromatography. Further, the present invention is directed toward pharmaceutical compositions comprising one or more antibodies of the present invention.
US08895706B2 Chromatography matrices including novel Staphylococcus aureus protein A based ligands
The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylooccus aureus Protein A (SpA), as well as methods of using the same.
US08895702B2 Development of masked therapeutic antibodies to limit off-target effects; application to anti-EGFR antibodies
In one embodiment, a masked monoclonal antibody (mAb) is provided, the mAb, encoded by a nucleic acid sequence or an amino acid sequence molecule comprising a signal sequence, a masking epitope sequence, a linker sequence that is cleavable by a protease specific to a target tissue; and an antibody or a functional fragment thereof. In another embodiment, a cross-masked mAb heterodimer complex is provided, comprising a first masked mAb, comprising a first signal sequence, a first masking epitope sequence, a first linker that is cleavable by a protease specific to a target tissue, and a first antibody or fragment thereof; and a second masked mAb, comprising a second signal sequence, a second masking epitope sequence, a second linker that is cleavable by a protease specific to a target tissue, and a second antibody or fragment thereof.
US08895700B2 Monkey homolog of human interferon omega
Cytokine IFNω nucleic acids from the Cynomolgus monkey are useful for expression of IFNω proteins that are functional homologs of human IFNω. The nucleic acids and proteins produced therefrom are useful in screening and safety testing of IFNω, the generation and testing of IFNω modulators and related activities.
US08895696B1 Methods for forming peptides and peptide conjugates and peptides and peptide conjugates compositions formed thereby
Methods for building peptide chains containing sulfonyl modified amines at the N-terminus, or, within amino acid side chains, of a growing peptide in a solid-phase peptide synthesis are described. Further, compositions having a sulfonyl modified amine attached to the N-terminus, or within an amino acid side chain, of a polypeptide containing three or more amino acid residues are described.
US08895693B2 Electron-donating polymers and organic solar cells including the same
An electron-donating polymer including a repeating unit A with a repeating unit represented by Chemical Formula 1 and at least one of repeating units represented by Chemical Formulae 2-4.
US08895690B2 Copolymerized polyamide resin, method for producing same, resin composition, and molded article formed from the copolymerized polyamide resin or the resin composition
A copolyamide resin for molding including a diamine component which includes two or more diamines and a dicarboxylic acid component. The diamine component includes 70 mol % or more of a xylylenediamine which includes 20 mol % or more of p-xylylenediamine and the dicarboxylic acid component includes 70 mol % or more of a straight-chain aliphatic dicarboxylic acid having 6 to 18 carbon atoms. The copolyamide resin contains particles having a major diameter of 50 μm or more in an amount of 1000 particles/g or less, the particles being made of a polyamide having a melting point higher than that of the copolyamide resin by 20° C. or more when measured by a differential scanning calorimetry. The copolyamide resin has very uniform and stable properties and is excellent in any of mechanical properties, heat resistance, chemical and physical properties, and molding properties. An efficient production method of the copolyamide resin, its resin composition, and its molded article are also described.
US08895684B2 Modified polymer compositions
The invention provides a first composition comprising at least the following: i) a modified polymer comprising at least one branched modified polymer macromolecule (b1) and at least one linear modified polymer macromolecule (a1), and wherein the at least one branched modified polymer macromolecule and the at least one linear modified polymer macromolecule each, independently, comprises at least one amine group selected from the group consisting of formulas (1A-1F), each as described above Formula 1A, Formula 1B, Formula 1C, Formula 1D, Formula 1E, Formula 1F, and combinations thereof; and wherein the at least one branched modified polymer macromolecule further comprises one of the structures (ib1-ib4) as described above, and the at least one linear modified polymer macromolecule further comprises one of the structures (iib1-iib2) as described above.
US08895681B2 Processes for preparing low molecular weight hexafluoropropylene-olefin cotelomers
Amorphous hydrofluoroolefin telomers are prepared by a free-radical polymerization process conducted at high temperature and pressure in the presence of non-monomeric chain transfer agent.
US08895680B2 Redox curing-type nonaqueous curable composition
The present invention relates to redox-curing type nonaqueous curable compositions having: at least one liquid radical polymeric monomer (a); an organic peroxide (b); and a powdered water-soluble reducing compound (c), where the powdered water-soluble reducing compound (c) is dispersed in the liquid radical polymeric monomer (a).
US08895676B2 Resin composition and display device using the same
The resin composition of the present invention is a resin composition characterized by including (a) a polyimide, a polybenzoxazole, a polyimide precursor or a polybenzoxazole precursor, (b) 1,5-dihydroxynaphthalene, 1,6-dihydroxynaphthalene, 1,7-dihydroxynaphthalene, or 2,3-dihydroxynaphthalene, and (c) a thermal cross-linking agent having a specific structure. By the use of the resin composition of the present invention, it is possible to reduce the transmittance in the visible region of a cured film while maintaining the transmittance of a resin film before curing.
US08895675B2 Block copolymer
A block copolymer comprising two or more of blocks of the following formula (1), wherein at least two of a plurality of m's present in the copolymer represent a number of 5 or more, Ar's in adjacent two blocks in the copolymer are mutually different, and the copolymer has two Ar's when composed of 2 blocks of the formula (1), has two or more Ar's when composed of 3 blocks of the formula (1) and has four or more Ar's when composed of 4 or more blocks of the formula (1): (in the formula (1), Ar represents a conjugative divalent group and represents the same divalent group in an identical block, and m represents a number of 1 or more showing the number average polymerization degree of Ar present in one block).
US08895673B2 Macromonomers for preparation of degradable polymers and model networks
The present invention relates to methods for preparing degradable model networks from any monomer functionality with any degradation methodology. It is based on the use of Atom-Transfer Radical Polymerization and CLICK chemistry to form the desired product.
US08895672B2 Production of vinylidene-terminated and sulfide-terminated telechelic polyolefins via quenching with disulfides
Provided herein are methods for preparing vinylidene-terminated polyolefins. Further provided herein are sulfide-terminated polyolefins.
US08895671B2 Carbon nanotube containing rubber compositions
The present invention provides a vulcanizable composition containing a specific hydrogenated nitrile rubber, at least one cross-linking agent and carbon nanotubes, a process for preparing such composition and the use thereof for preparing vulcanizates. Said vulcanizates exhibit excellent heat performance, oil resistance and mechanical strength.
US08895667B2 Methods of making reversible crosslinked polymers and related methods
Methods are provided for making reversible crosslinked polymers. Exemplary methods comprise reacting first and second thermoplastic polymers having non-hindered olefins in the presence of a metathesis catalyst under conditions sufficient to form a crosslinked polymer. In certain embodiments, the methods comprise providing a crosslink promoting additive to improve the strength of the crosslinked polymer. In some embodiments, the methods comprise decrosslinking a crosslinked polymer through a metathesis or an ozonolysis reaction.
US08895665B2 Modified conjugated diene polymer and synthesis method thereof
Provided is a synthesis method of a modified conjugated diene polymer. Conjugated diene monomers are reacted in a reaction system. A modifier is added into the reaction system while the reaction proceeds to a predetermined extent. The modifier has a structure represented by formula (1): wherein R1-R11 each independently represent a C1-C5 alkyl group; 1≦m≦300; 0≦a≦65; 0≦b≦65; 0≦c≦40; 0
US08895663B2 Polycarbonate resin composition and molded article thereof
The present invention relates to a polycarbonate resin composition, comprising: a polycarbonate resin containing a structural unit derived from a dihydroxy compound having a moiety represented by the following formula (1) [provided that a case where the moiety represented by formula (1) is a moiety constituting —CH2—O—H is excluded]; and an elastomer composed of a core•shell structure, wherein a core layer of the elastomer is at least one member selected from the group consisting of an alkyl (meth)acrylate and a (meth)acrylic acid, and a polycarbonate resin molded article obtained by molding the polycarbonate resin composition: CH2—O  (1).
US08895662B2 Curable composition and method for manufacturing the same
A curable composition comprises the following: (A) a branched polymer having an average unit formula (I′): [(R″)2SiO2/2]a″[(CH2═CH)(R″)2SiO1/2]b″[R″SiO3/2]c″[O1/2Si(R″)2(CH2CH2)(R″)2SiO1/2]e″; (B) a branched organopolysiloxane having at least one silicon-bonded alkenyl group and having a siloxane unit of formula R4SiO3/2; (C) an organopolysiloxane having an average unit formula (II) being capped with H: (R52SiO2/2)f(R63SiO1/2)g(R7SiO3/2)h(SiO4/2)i(CH2CH2)j; and (D) a catalyst, wherein R″, R4 to R7, a″ to c″, e″ and f to j are as defined in the specification.
US08895661B2 Plastic lens
A plastic lens having excellent weather resistance, formed by polymerization of a composition containing a polyisocyanate compound having an aromatic ring and a polythiol compound is provided. The plastic lens is formed by polymerization of a composition that contains 100 parts by mass in total of (A) a polyisocyanate compound containing a polyisocyanate compound having an aromatic ring and (B) a polythiol compound, from 0.5 to 5.0 parts by mass of (C) a benzophenone compound having a hydroxyl group on at least the ortho position, and from 0.5 to 5.0 parts by mass of (D) a phenol compound.
US08895658B2 Grafted pigment dispersing polymeric additive and paint employing the same with improved hiding
The present invention relates to a grafted pigment dispersing polymeric additive for opacifying pigments, prepared by polymerizing monomers in the presence of a polymeric pigment dispersant. The polymeric pigment dispersant has low molecular weight, high acid number and is dissolvable in alkali solution. When incorporated into paint compositions, hiding is improved with less opacifying pigments.
US08895657B2 Vinyl chloride resin aggregate particles, process for producing same, and glove obtained using same
The present invention provides: vinyl chloride-based resin aggregate particles that can be produced through a heat treatment while inhibiting scale formation within a vessel for the heat treatment and that provide a plastisol with non-infiltrating property and a satisfactory sagging property; a process for producing the particles; and a glove obtained using the particles. The vinyl chloride-based resin aggregated particles are obtained by flocculating a vinyl chloride-based resin through a two-stage heat treatment consisting of a primary heat treatment and a secondary heat treatment.
US08895653B2 Acrylic adhesive composition, and pressure-sensitive adhesive sheet employing the same
There is provided an acrylic adhesive composition which comprises: (A) a vinyl polymer comprising a homopolymer or a copolymer of an alkyl (meth)acrylate having a C4 to C14 alkyl group; (B) an organophilic layered double hydroxide organically treated with an organic anion; and (C) a crosslinking agent. Therefore the obtained adhesive composition has sufficient adhesiveness to an object, excellent heat resistance and excellent adhesive properties particularly at higher temperatures, and is substantially free from variations in adhesiveness.
US08895650B2 Phthalate-free isocyanurate formulations
The present invention relates to novel low-monomer low-viscosity high-activity formulations composed of isocyanurate containing isocyanate groups, exclusively based on 2,4-diisocyanatotoluene and phthalate-free plasticizers, to the use thereof as adhesion promoters with improved adhesion for coating compositions based on plasticized polyvinyl chloride, and to coatings and coated substrates.
US08895646B2 Pigment dispersion and method for producing resin-treated pigment in the pigment dispersion
Disclosed are a resin-treated pigment characterized in that the resin-treated pigment comprises a pigment and a polymer of an unsaturated bond-containing monomer, a weight ratio of the pigment to the polymer (pigment:polymer) is from 50 to 95 to from 5 to 50, and the polymer is a block copolymer comprising from 5 to 70 mass % of an addition-polymerizable monomer having a UV-absorbing group; a production process of the resin-treated pigment; and a pigment dispersion using the resin-treated pigment.
US08895645B2 Polymer-modified asphalt compositions
A modified-asphalt composition prepared by introducing a diene end-capped block copolymer with a molten asphalt composition, where the block copolymer is defined by the formula α-(D-V-d)x where each D is independently a polydiene block, each V is independently a vinyl aromatic block, each d is a polydiene end cap, α is a coupling moiety, and x is an integer from 2 to 10.
US08895642B2 Buoyancy control material for subsea main pipelines and high-density buoyancy control material for subsea main pipelines
The buoyancy control material for subsea main pipelines and high-density buoyancy control material for subsea main pipelines are suggested predominantly for use while manufacturing pipes for subsea pipeline installations. Creation of a buoyancy control material with a density greater than 2800 kg/m3 and the required mobility is an engineering problem solved by this invention. The buoyancy control material for subsea main pipelines contains cement, filler, plasticizing agent and water.
US08895638B2 Ultraviolet ray curable ink jet composition and printed object
An ultraviolet ray curable ink jet composition of the present invention is characterized by being adapted to be ejected using an ink jet method and containing: a polymerizable compound; metal particles subjected to a surface treatment; and a substance A having a partial structure represented by the following formula (1), where R1 is a hydrogen atom, an oxygen radical, a hydrocarbon group or an alkoxy group, and each of R2, R3, R4 and R5 is independently a hydrogen atom or a hydrocarbon group.
US08895632B2 Anthracene derivative, compound obtained therefrom, composition, cured product, and process for producing same
An object of the invention is to provide an anthracene derivative having characteristics peculiar to anthracene such as e.g., high carbon density, high melting point, high refractive index and fluorescent properties for ultraviolet rays, etc., and reaction diversity that results from the bisphenol structure, and a process for producing the same. Disclosed is an anthracene derivative represented by the following general formula (1): in the formula (1), X and Y each independently represent a hydroxyaryl group. The aforementioned X and Y are preferably a hydroxyphenyl group. In addition, the anthracene derivative can be produced by a process including allowing at least one compound selected from phenols and anthracene-9-carboaldehyde to react in the presence of an oxygen-containing inert organic solvent and an acid catalyst.
US08895630B2 Non-ionic associative thickeners containing alkyl cyclohexylols, formulations containing them and their uses
New associative thickeners of the HEUR type (Hydrophobically modified Ethylene oxide URethane) whose hydrophobic monomer is based on alkyl cyclohexylols. These are new polyurethanes that allow a broad thickening of a medium shear gradient aqueous formulation while limiting the increase in the low shear gradient viscosity. The invention also concerns the compositions containing them and their uses in different formulations such as aqueous paints.
US08895628B2 Compositions comprising a retinoid and an NFkB-inhibitor and their methods of use
A composition including a retinoid, an NFκB-inhibitor, and a cosmetically-acceptable topical carrier is provided. Methods of treating the skin are also provided.
US08895627B2 Method to elicit tomato resistance to fungal disease
The present invention provides an essential oil containing cineole for eliciting tomato resistance to disease by fungal infection. The present invention also provides a method to elicit tomato resistance to disease by fungal infection.
US08895625B2 Protective effect of thymoquinone in sepsis
The present invention refers to thymoquinone, a main constituent of the volatile oil of Nigella sativa, and its protective effect against sepsis syndrome morbidity, mortality and associated organ dysfunctions. In particular, the present invention refers to thymoquinone for use in the prevention and/or treatment of sepsis syndrome. The present invention further refers to a pharmaceutical composition and a kit.
US08895616B1 Composition and method for treating neurological disease
Disclosed are compositions comprising amantadine, or a pharmaceutically acceptable salt thereof, and one or more excipients, wherein at least one of the excipients modifies release of amantadine. Methods of administering the same are also provided.
US08895612B2 Methods and compositions for administration of iron
The present invention generally relates to treatment of iron-related conditions with iron carbohydrate complexes. One aspect of the invention is a method of treatment of iron-related conditions with a single unit dosage of at least about 0.6 grams of elemental iron via an iron carbohydrate complex. The method generally employs iron carbohydrate complexes with nearly neutral pH, physiological osmolarity, and stable and non-immunogenic carbohydrate components so as to rapidly administer high single unit doses of iron intravenously to patients in need thereof.
US08895609B2 Methods for treating attention-deficit/hyperactivity disorder
The invention is directed to a method of treating attention-deficit/hyperactivity disorder (ADHD) in a subject, comprising administering a therapeutically effective amount of a carbamoyl compound, or pharmaceutically acceptable salt thereof.
US08895607B2 Inhibitors of the amino acid transporters ASCT1 and ASCT2
The present invention relates to a compound of Formula (I) or (II) or a salt thereof, wherein R is described herein. The compounds are novel hydroxy-proline analog inhibitors of the ASCT1 and ASCT2 neutral amino acid transporters.
US08895606B2 Proline sulfonamide derivatives as orexin receptor antagonists
The present invention relates to (S)-proline sulfonamide compounds of formula (I) wherein R1 and R2 are as described in the description, or pharmaceutically acceptable salts thereof, for use in the prevention or treatment of diseases or disorders related to the orexin system. The present invention also relates to the use of (S)-proline sulfonamide compounds of formula (II) as pharmaceuticals, to pharmaceutical compositions comprising compounds of formula (II), and especially their use in the prevention or treatment of diseases or disorders related to the orexin system.
US08895603B2 Crystalline forms of a dipeptidyl peptidase-IV inhibitor
Novel crystalline forms of (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine are potent inhibitors of dipeptidyl peptidase-IV and are useful for the treatment of non-insulin dependent (Type 2) diabetes mellitus. The invention also relates to pharmaceutical compositions containing these novel forms, processes to prepare these forms and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes.
US08895602B1 6-pyrazolylamido-3-substituted azabicyclo[3.1.0]hexane compounds as calcium channel inhibitors
The present invention relates to a 6-pyrazolylamido-3-substituted azabicyclo[3.1.0]hexane derivatives useful as calcium channel blockers, pharmaceutically acceptable salts thereof and medical use of the calcium channel inhibiting effect of the compounds for treatment of diseases.
US08895601B2 Pyrazolyl quinoxaline kinase inhibitors
The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
US08895599B2 Lipoprotein lipase-activating compositions comprising benzene derivates
The present invention provides pharmaceutical compositions containing benzene compound(s) represented by General Formula (1) below and, particularly, LPL-activating compositions for use in hyperlipidemia therapeutic and preventive agents, anti-obesity agents, and the like: wherein R1, R2, R3 and R4 are as defined in the specification.
US08895592B2 Compounds as cannabinoid receptor ligands
Disclosed herein are cannabinoid receptor ligands of formula (I) wherein L1, A1, R1g, z, R2, R3, and R4 are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also presented.
US08895591B2 Tricyclic compound and pharmaceutical use thereof
The present invention provides a compound represented by the formula which is useful as an agent for the prophylaxis or treatment of diseases related to the action of melatonin, or a salt thereof and the like.
US08895589B2 Pyridinyl amides as P2X3 and P2X2/3 inhibitors
Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted phenyl or optionally substituted pyridinyl, and R2, R3, R4, R5, R6, R7, R8 and R9 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.
US08895587B2 Insecticidal compounds based on arylthioacetamide derivatives
The present invention provides compounds of formula (I) wherein R1, R2, R3, R4, G1, n, A1, A2, A3, A4, Y1, Y2, and Y3 are as defined in the claims. The invention also relates to processes and intermediates for preparing these compounds, to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising these compounds and to methods of using these compounds to control insect, acarine, nematode and mollusc pests.
US08895585B2 Nicotinamide derivative or salt thereof
An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. The present invention provides a nicotinamide derivative represented by the following formula (I) (wherein R1 represents a halogen atom; R2 represents a C1-12 alkyl group, a C2-12 alkenyl group, a C2-12 alkynyl group, a C3-8 cycloalkyl group, an aryl group, an ar-C1-6 alkyl group or a heterocyclic group, each optionally having at least one substituent; R3 represents an aryl group or a heterocyclic group each optionally having at least one substituent; and R4 and R5 each independently represent a hydrogen atom; and R2 and R4 may form a cyclic amino group optionally having at least one substituent together with the nitrogen atom to which they bind) or a salt thereof, and a pharmaceutical composition for use in the treatment of a Syk-related disease which comprises the nicotinamide derivative or a salt thereof.
US08895571B2 Isoindolinone and pyrrolopyridinone derivatives as Akt inhibitors
The present invention provides isoindolinone and pyrrolopyridinone derivatives, as well as their compositions and methods of use, that inhibit the activity of the serine/threonine kinase, Akt, and are useful in the treatment of diseases related to the activity of Akt including, for example, cancer and other diseases.
US08895570B2 Purine derivatives
The invention provides the compound of formula (I) and pharmaceutically acceptable salt thereof, pharmaceutical compositions containing the compound and the use of the compound in therapy.
US08895568B2 Compositions comprising substituted pteridines as agrochemicals
The present disclosure relates to 1- or 2-(4-(aryloxy)-phenyl)ethylamino-oxy- or sulfanyl) pteridines and 1- or 2-(4 Jheteroaryloxy)-phenyl)ethylamino-, oxy- or sulfanyl)pteridines and their use as agrochemicals and animal health products. The disclosure provides compounds of Formula (I-A) and Formula (I-B).
US08895565B2 Heterocyclic compound and use of the same
Provided is a compound represented by general formula (6) and pharmaceutically acceptable salts thereof. (In the formula, R1 is a hydrogen atom or a C1-6 alkyl group; R2 is a hydrogen atom or a C1-6 alkyl group; R3 is a hydrogen atom, a halogen atom, a C1-6 alkyl group, or a C1-6 haloalkyl group.)
US08895564B2 Biguanide derivative compound
Provided is a novel compound which simultaneously inhibits both NMDA receptors and ASIC1a, which are associated with neurodegenerative disease and so on, and thus is useful for the prevention and treatment of various nervous system diseases. A biguanide derivative represented by the following general formula (1), a salt thereof, or a hydrate of the derivative or the salt: wherein, X1 represents a halogen atom, R1 represents an alkyl group, an optionally substituted aryl group, or an optionally substituted aralkyl group.
US08895563B2 Human protein tyrosine phosphatase inhibitors and methods of use
The present disclosure relates to compounds effective as human protein tyrosine phosphatase beta (HPTP-β) inhibitors thereby regulating angiogenesis. The present disclosure further relates to compositions comprising said human protein tyrosine phosphatase beta (HPTP-β) inhibitors, and to methods for regulating angiogenesis.
US08895557B2 Pharmaceutical formulations of ecteinascidin compounds
Ecteinascidin formulations, methods of preparing the same, articles of manufacture and kits with such formulations, and methods of treating proliferative diseases with the same formulations are provided.
US08895555B2 Methods of treating intestinal diseases and inflammatory conditions related to HIV-AIDS
Provided herein are methods of treating intestinal diseases or inflammatory conditions, including HIV-AIDS, in which oxidative stress is a triggering or exacerbating factor by administering GVT to a patient suffering from the condition such that the condition is treated.
US08895549B2 Aminoalcohol substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.
US08895547B2 Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
The invention relates to the compounds of formula (I) and to the physiologically acceptable salts thereof. Said compounds are suitable e.g. for the treatment of hyperglycemia.
US08895545B2 Acrylamide derivatives as Fab I inhibitors
In part, the present invention is directed to antibacterial compounds.
US08895541B2 Methods for inhibiting the development of huntington's disease
This invention relates to Huntington's disease and more specifically to methods for inhibiting the development of or treating Huntington's disease by administering estrogen, testosterone, precursors thereof or combinations thereof.
US08895540B2 Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
This invention relates to local administration of a bone-forming agent and at least one anti-resorptive agent to treat osteoporosis and related disorders.
US08895539B2 Pregnancy hormone combination for treatment of autoimmune diseases
The present invention relates to pregnancy hormone combinations and methods of treatment for autoimmune diseases having at least two hormonal components, a pregnancy hormone (such as estriol), and a gestagen (such as levonorgestrel or norethindrone) thereby providing for the continuous, uninterrupted administration of pregnancy hormones for the treatment for autoimmune disorders, such as multiple sclerosis.
US08895535B2 Pyrrolidinones as MetAP-2 inhibitors
Compounds of the formula I in which R1, R2, R3 and R4 have the meanings indicated in Claim 1, are inhibitors of methionine aminopeptidase and can be employed for the treatment of tumors.
US08895531B2 2′-fluoronucleoside phosphonates as antiviral agents
The present invention includes compounds and compositions of ®-2′-fluoronucleoside phosphonates, as well as methods to treat HIV, HBV, HCV or abnormal cellular proliferation comprising administering said compounds or compositions.
US08895528B2 Treatment of atonal homolog 1 (ATOH1) related diseases by inhibition of natural antisense transcript to ATOH1
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Atonal homolog 1 (ATOH1), in particular, by targeting natural antisense polynucleotides of Atonal homolog 1 (ATOH1). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of ATOH1.
US08895525B2 Preventing hyaluronan-mediated tumorigenetic mechanisms using intronic RNAs
Patterns of microRNA (miRNA) expression are correlated to the degrees of tumor cell differentiation in human prostate cancer. MiRNAs can complementarily bind to either oncogenes or tumor suppressor genes, resulting in targeted gene silencing and thus changes of cellular tumorigenecity. Using miRNA microarray analysis, 8 down-regulated and 3 up-regulated known miRNAs in androgen-independent human prostate cancer cell lines, such as LNCaP C4-2B and PC3, compared to those androgen-dependent cell lines, such as LNCaP and PC3-AR9 were consistently detected. Fluorescent in-situ hybridization assays in human prostate cancer tissue arrays containing sixty patients at different stages also showed the same miRNA expression patterns in hormone-refractory prostate carcinomas (HRPC) compared to androgen-sensitive non-cancerous prostate epithelium. In-vitro tumorigenecity assays using one of the identified miRNAs, mir-146a, were performed to provide validation of its function in prostate cancer. Gain-of-function transfection of mir-146a markedly suppressed its targeted ROCK1 gene expression in androgen-independent PC3 cells, consequently resulting in reduced cancer cell proliferation, invasion and metastasis to human bone marrow endothelial cell monolayers. Since ROCK1 is the key kinase for activating hyaluronan-mediated HRPC transformation in vivo and in PC3 cells, mir-146a should function as a tumor-suppressor gene in modulating the ROCK1-associated tumorigenecity.
US08895523B2 Use of antisense oligonucleotides against CPLA2 in the treatment of cancer
Inhibitors of cPLA2α expression are used in the preparation of pharmaceutical compositions for the inhibition of cancer cell proliferation and for the treatment of cancer; the inhibitors are selected from cPLA2α-specific ribozymes, RNA sequences usable for RNA-interference of the cPLA2α gene, and antisense oligonucleotides directed against cPLA2α.
US08895522B2 Composition and method for the prevention, treatment and/or alleviation of an inflammatory disease
A method for enhancing the clinical responsiveness to an anti-inflammatory therapy in a patient afflicted with an inflammatory condition, comprising administering an oligonucleotide having the sequence 5′-Xm-CG-Yn-3′ in an effective amount to said patient, and wherein X is A, T, C or G; Y is A, T, C or G; m=1-40; n=1-40 and wherein at least one CG dinucleotide is unmethylated. The invention also encompasses the use of such an oligonucleotide for the manufacture of a medicament for enhancing steroid efficacy in the treatment of a patient afflicted with an inflammatory condition.
US08895521B2 Methods and compositions for the treatment of uveitis
Pharmaceutical compositions are disclosed that are of use for the treatment of uveitis. These compositions include a suppressive oligonucleotide. These compositions including an immunosuppressive oligonucleotide can be used for the treatment of uveitis, including anterior, posterior, and diffuse uveitis.
US08895520B2 Method for treating a human patent suffering from Myeloid Neoplasias using 5-aminoimidazole-4-carboxamide
A method of treatment of a human patient suffering from myeloid neoplasias, includes administrating a therapeutically effective amount of 5-aminoimidazole-4-carboxamide (acadesine), acadesine precursors or acadesine derivatives.
US08895517B2 Pesticidal composition and its use
A composition comprising a carboxamide compound represented by following formula (I), wherein R1 represents a hydrogen atom or a methyl group, and R2 represents a methyl group, a difluoromethyl group or a trifluoromethyl group, and abamectin is provided by the present invention, and this composition has an excellent pesticidal effect.
US08895512B2 Composition for improving brain function and method for improving brain function
The present invention provides a composition which may be ingested orally in a small dose for the purpose of improving brain function, and a method for improving brain function. The present invention is a composition for improving brain function, comprising, as an active ingredient, Phe-Pro.
US08895511B2 Use of sarcoplasmic CA2+-ATPase type 2 protein for diagnosing and treating learning or mental disorders
The present invention embraces methods for the diagnosis and treatment of learning or mental disorders, as well as the identification of agents useful in the treatment of such disorders based upon the identified involvement of Sarcoplasmic Ca2+-ATPase type 2 Protein in synaptic plasticity and neurotransmitter release in 22q11 deletion/DiGeorge Syndrome.
US08895506B2 Protein stabilization formulations
The present invention is directed to stabilizing Bone Morphogenetic Protein in various lyophilized formulations and compositions. The present invention comprises formulations primarily including trehalose as an excipient for lyophilized compositions and their subsequent storage and reconstitution, and can also optionally include other excipients, including buffers and surfactants.
US08895505B2 Method of treatment of type 2 diabetes
Provided is a method of treating type 2 diabetes in a subject, comprising administering a polypeptide comprising thymosin, or an active fragment or variant thereof, preferably comprising or consisting of the peptide LKKTETQ (SEQ ID NO: 1).
US08895504B2 Amylin derivatives
Amylin derivatives, pharmaceutical compositions containing such derivatives, as well as methods of treating diabetes and hyperglycaemia are disclosed.
US08895501B2 Eye-drop vaccine containing copolymer 1 for therapeutic immunization
The invention provides an eye-drop vaccine for therapeutic immunization of a mammal comprising Copolymer 1, a Copolymer 1-related peptide, or a Copolymer 1-related polypeptide, for treating neuronal degeneration caused by an injury or disease, disorder or condition in the central nervous system (CNS) or peripheral nervous system (PNS), for preventing or inhibiting neuronal secondary degeneration which may otherwise follow primary injury in the CNS, for promoting nerve regeneration in the CNS or in the PNS after an injury, disease, disorder or condition or for protecting CNS and PNS cells from glutamate toxicity.
US08895499B2 β-hairpin peptidomimetics
β-Hairpin peptidomimetics of the general formula Cyclo(-Xaa1-Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-Xaa8-Xaa9-Xaa10-Xaa11-Xaa12-Xaa13-Xaa14-), enantiomers and pharmaceutically acceptable salts thereof, with Xaa1-Xaa14 being amino acid residues of certain types which are defined in the description and the claims, have anti-infective activity, e.g. to selectively inhibit the growth of or to kill microorganisms such as Bacillus subtilis and/or Shigella boydii. They can be used as medicaments to treat or prevent infections or as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials. These peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.
US08895492B2 Dilutable concentrated cleaning composition comprising a divalent metal salt
This application relates to a dilutable aqueous liquid cleaning composition, typically a dishwashing liquid, which comprises a plurality of surfactants, the surfactants including surfactant active components comprising from greater than 30% to up to 55% by weight, based on the weight of the composition, wherein the composition has a viscosity of 100 to 500 mPas as measured at 25° C., and the composition is dilutable with water to form a non-gelling diluted composition having up to six times the volume of the undiluted composition and a viscosity within the range of 100 to 1600 mPas as measured at 25° C. at any dilution up to the six times dilution.
US08895491B2 Concentrated cleaning compositions and their use
The present disclosure relates to a concentrated acidic floor cleaner and methods of using it to clean floors. The concentrated acidic floor cleaner can be diluted to form a use solution that is effective at removing polymerized grease, including animal and vegetable fats and non-trans fats, and other soils from floors. The use solution is especially useful for cleaning floors in commercial kitchens of full service and quick service restaurants and is effective on a variety of floors, including quarry tile.
US08895488B2 Sliding structural members
A sliding structural member is provided which achieves a good low frictional property. A DLC film 2 containing hydrogen is provided on one member 11 between members sliding against each other, and the one member and a counterpart member 12 are combined in such a way that the DLC film 2 provided on the one member 11 slides against the counterpart member via a lubricant 3 to which organic molybdenum compound and compound containing zinc and sulfur are added as an additive. A root mean square roughness of a surface of the DLC film 2 is set in a range from 5 nm or more to 25 nm or less, and hydrogen content of the DLC film 2 is set in a range from 4.5 at % (atomic %) or more to 30 at % or less.
US08895487B2 Cement composition containing an additive of a pozzolan and a strength retrogression inhibitor
A cement composition comprises: cement; water; and an additive, wherein the additive is a pozzolan and a strength-retrogression inhibitor, and wherein a mixture consisting essentially of: the additive; water; and a source of calcium develops a compressive strength of at least 500 psi at a time of 24 hours, a temperature of 190° F., and a pressure of 3,000 psi. A method of cementing in a subterranean formation comprises: introducing the cement composition into the subterranean formation and allowing the cement composition to set. The compressive strength of the test cement composition consisting essentially of: the cement; the water; and the additive at a final time of 72 hours has a percent change greater than −5% from the compressive strength of the test cement composition at an initial time of 24 hours when tested at a temperature of 300° F. and a pressure of 3,000 psi.
US08895486B2 Methods and compositions comprising cement kiln dust having an altered particle size
Methods and compositions are disclosed that comprise cement kiln dust having a mean particle size that has been altered. An embodiment discloses a method of preparing cement kiln dust comprising: providing cement kiln dust having an original particle size; and altering the mean particle size of the cement kiln dust from the original size by grinding, separating, or a combination thereof. Another embodiment discloses a well treatment fluid comprising: cement kiln dust having a mean particle size that has been altered from its original size by grinding, separating, or a combination thereof; and water.
US08895484B2 Use of biphenyl, terphenyl, and fluorene sulphonic acid based tracers for monitoring streams of fluids
Biphenylmono- and polysulphonic acids and salts thereof, fluorenemono- and polysulphonic acids and salts thereof as well as p-terphenylmono- and polysulphonic acids and salts thereof may be used successfully as tracers for surveying, monitoring and/or measuring movements of aqueous fluids in aqueous and/or non-aqueous media. Said substances are especially suited for surveying or monitoring movements of fluids in oil wells or reservoirs as well as for fluid movements in hydrothermal reservoirs.
US08895483B2 Disproportionate permeability reduction using a viscoelastic surfactant
The invention discloses a method of for changing the water permeability of a subterranean formation of a well, the method comprising: providing a fluid comprising a liquid carrier and a viscoelastic surfactant; introducing the fluid into the well; and contacting the fluid and the subterranean formation wherein the action of the liquid carrier and the viscoelastic surfactant is able to change the water permeability of the subterranean formation. The fluid may further comprise methanol, or a salt which can be embodied within the carrier fluid. Advantageously, no further RPM polymer is used. In a first aspect the method is used for reducing the amount of water produced, in as second aspect for improving the oil recovery.
US08895478B2 Degradable polymer compositions and uses thereof
The invention relates to novel polymers derived from: (A) at least one N-vinyl amide-based unit and/or at least one acrylamide-based unit, and (B) at least one unit comprising: (i) at least one hydroxyl group, and/or (ii) at least one functional group convertible to a hydroxyl group wherein at least one group is converted to hydroxyl functionality in the final polymer product, wherein the polymer comprises at least one ester group. The polymers and compositions are used in oilfield applications, such as an inhibitor of gas hydrates and/or a kinetic inhibitor of gas hydrates. The polymer can assume alternating, block, and/or random configurations of the repeating units, with at least one ester group.
US08895476B2 Thermal insulating fluids
Aqueous and substantially anhydrous fluids having particularly low thermal conductivities and variable densities are disclosed. The fluids include: one or more organic and/or inorganic salts and at least one aprotic polar organic solvent, a mixture of aprotic and protic polar organic solvents, and/or a polar organic solvent having both protic and aprotic polar functional group linkages. The fluids optionally include one or more viscosifying agents and are free of cross-linking agents. Methods for formulating and using the fluids are also disclosed.
US08895475B2 Focused libraries of genetic packages
Focused libraries of vectors or genetic packages that display, display and express, or comprise a member of a diverse family of antibody peptides, polypeptides or proteins and collectively display, display and express, or comprise at least a portion of the focused diversity of the family. The libraries have length and sequence diversities that mimic that found in native human antibodies.
US08895474B2 Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds
Compounds of Formula (I), wherein the substituents are as defined in claim 1, are suitable for use as herbicides.
US08895473B2 Aqueous composition for raising antioxidant enzyme activities and enhancing cell membrane-stability in plants exposed to low temperature
Present invention provides an aqueous composition made from selected biochemical substances that will help with the low temperature tolerance of plants and thus to avoid “chilling injury” and to promote better recovery from such injury, when the solution is applied to crop plants prior to the arrival of cold snap or period of low temperature.
US08895469B2 Alumina support, a process for preparing the support, a silver catalyst prepared from the support, and use thereof
An alumina support comprises alpha-alumina as the main crystal phase of its backbone, and having a specific surface area of no higher than 3.0 m2/g, a pore volume ranging from 0.3 ml/g to 0.8 ml/g, an alkaline earth metal content ranging from 0.05% to 2.0% by weight of the support, wherein the support has such properties that treating the support with an aqueous oxalic acid solution having a concentration ranging from 0.4% to 2.0% by weight and having twice the weight of the support for 30 minutes can produce a leach liquor having an aluminum content of no higher than 60 μg/mL, a sodium content of no higher than 20 μg/mL, and a silicon content of no higher than 40 μg/mL. Processes for preparing the alumina support, silver catalysts comprising the alumina support, and methods of preparing ethylene oxide by ethylene oxidation using the silver catalyst are also disclosed herein.
US08895457B2 Method of manufacturing semiconductor device and substrate processing apparatus
To provide a method of manufacturing a semiconductor device, including: forming a thin film different from a silicon oxide film on a substrate by supplying a processing gas into a processing vessel in which the substrate is housed; removing a deposit including the thin film adhered to an inside of the processing vessel by supplying a fluorine-containing gas into the processing vessel after executing forming the thin film prescribed number of times; and forming a silicon oxide film having a prescribed film thickness on the inside of the processing vessel by alternately supplying a silicon-containing gas, and an oxygen-containing gas and a hydrogen-containing gas into the heated processing vessel in which a pressure is set to be less than an atmospheric pressure after removing the deposit.
US08895455B2 Method for manufacturing semiconductor device and substrate processing apparatus
To form an insulating film with extremely low concentration of impurities such as carbon, hydrogen, nitrogen, chlorine, etc in a film. There are provided the steps of forming a specific element-containing layer on a substrate by supplying source gas containing a specific element into a processing container in which the substrate is accommodated; changing the specific element-containing layer into a nitride layer, by activating and supplying gas containing nitrogen into the processing container; and changing the nitride layer into an oxide layer or an oxynitride layer, by activating and supplying gas containing oxygen into the processing container; with this cycle set as one cycle and performed for at least one or more times.
US08895454B2 Etching method of multilayer film
In an etching method of a multilayer film including a first oxide film and a second oxide film, a high frequency power in etching an organic film is set to be higher than those in etching a first and second oxide films, and high frequency bias powers in the etching of the first and second oxide films are set to be higher than that in the etching of the organic film. In the etching of the first and second oxide films and the organic film, a magnetic field is generated such that horizontal magnetic field components in a radial direction with respect to a central axis line of a target object have an intensity distribution having a peak value at a position far from the central axis line, and a position of the peak value in the etching of the organic film is closer to the central axis line.
US08895450B2 Low resistivity tungsten PVD with enhanced ionization and RF power coupling
Embodiments described herein provide a semiconductor device and methods and apparatuses of forming the same. The semiconductor device includes a substrate having a source and drain region and a gate electrode stack on the substrate between the source and drain regions. In one embodiment, the method includes positioning a substrate within a processing chamber, wherein the substrate includes a source and drain region, a gate dielectric layer between the source and drain regions, and a conductive film layer on the gate dielectric layer. The method also includes depositing a refractory metal nitride film layer on the conductive film layer, depositing a silicon-containing film layer on the refractory metal nitride film layer, and depositing a tungsten film layer on the silicon-containing film layer.
US08895447B2 Semiconductor hole structure
A first dielectric layer is formed over a substrate. A second dielectric layer is formed over the first dielectric layer. A first opening is formed in the second dielectric layer. A second opening is formed in the first dielectric layer.
US08895442B2 Cobalt titanium oxide dielectric films
Electronic apparatus and methods of forming the electronic apparatus include cobalt titanium oxide on a substrate for use in a variety of electronic systems. The cobalt titanium oxide may be structured as one or more monolayers. The cobalt titanium oxide may be formed by a monolayer by monolayer sequencing process such as atomic layer deposition.
US08895441B2 Methods and materials for anchoring gapfill metals
One aspect of the present invention includes a method of fabricating an electronic device. According to one embodiment, the method comprises providing a substrate having dielectric oxide surface areas adjacent to electrically conductive surface areas, chemically bonding an anchor compound with the dielectric oxide surface areas so as to form an anchor layer, initiating the growth of a metal using the electrically conductive surface areas and growing the metal so that the anchor layer also bonds with the metal. The anchor compound has at least one functional group capable of forming a chemical bond with the oxide surface and has at least one functional group capable of forming a chemical bond with the metal. Another aspect of the present invention is an electronic device. A third aspect of the present invention is a solution comprising the anchor compound.
US08895438B2 Method for forming a multi-level surface on a substrate with areas of different wettability and a semiconductor device having the same
The invention relates to a method 10 for forming a multi-level surface on a substrate 2, wherein said surface comprises areas of different wettability, the method comprising the step (A, B) of applying a multi-level stamp to the substrate for forming the multi-level surface, said multi-level stamp having different structural regions 1a arranged along the multi-level surface for locally altering wettability properties of at least a portion of a level of the multi-level surface 2a, 2b. The invention further relates to a semiconductor device and a method for manufacturing a semiconductor device.
US08895436B2 Implementing enhanced power supply distribution and decoupling utilizing TSV exclusion zone
Methods and structures implement enhanced power supply distribution and decoupling utilizing Through-Silicon-Via (TSV) exclusion zone areas for contacting one or more metal wiring layers on a semiconductor chip. A first wiring level in the TSV exclusion zone area includes a first wiring shape having a first hole of a first diameter. A dielectric includes second hole of a second diameter larger than the first diameter is provided above the first wiring level concentric with the first hole. A via hole extends through the first and second holes and an etch is performed to expose a top surface portion of the first wiring shape. A thin oxide is grown over the entire bore of the hole; an anisotropic etch is provided to remove horizontal portions of the thin oxide, exposing wiring shapes. The via hole is filled with a selected material to make TSV electrical connection to the exposed wiring shape.
US08895435B2 Polysilicon layer and method of forming the same
The method of forming a polysilicon layer is provided. A first polysilicon layer with a first grain size is formed on a substrate. A second polysilicon layer with a second grain size is formed on the first polysilicon layer. The first grain size is smaller than the second grain size. The first polysilicon layer with a smaller grain size can serve as a base for the following deposition, so that the second polysilicon layer formed thereon has a flatter topography, and thus, the surface roughness is reduced and the Rs uniformity within a wafer is improved.
US08895434B2 Replacement metal gate structure for CMOS device
A method of fabricating a replacement metal gate structure for a CMOS device including forming a dummy gate structure on an nFET portion and a pFET portion of the CMOS device; depositing an interlayer dielectric between the dummy gate structures; removing the dummy gate structures from the nFET and pFET portions, resulting in a recess on the nFET portion and a recess on the pFET portion; conformally depositing a gate dielectric into the recesses on the nFET and pFET portions; depositing sequential layers of a first titanium nitride, tantalum nitride and a second titanium nitride into the recesses on the nFET and pFET portions; removing the second layer of titanium nitride from the nFET portion only; depositing a third layer of titanium nitride into the recesses on the nFET and pFET portions; and filling the remainder of the cavity on the nFET and pFET portions with a metal.
US08895432B2 Method of fabricating a self-aligned buried bit line for a vertical channel DRAM
A method of fabricating a self-aligned buried bit line in a structure which makes up a portion of a vertical channel DRAM. The materials and processes used enable self-alignment of elements of the buried bit line during the fabrication process. In addition, the materials and processes used enable for formation of individual DRAM cells which have a buried bit line width which is 16 nm or less.
US08895427B2 Substrate having a transparent electrode and method for producing the same
A zinc oxide transparent electroconductive oxide has been difficult to use as a substrate having a transparent electrode because the oxide, when configured as a thin film, because of increased resistivity due to air and/or moisture exposure. Though doping can inhibit increase of resistance to some extent, there has been difficulty in selecting a type and an amount of a doping substance and because doping causes high initial resistance. A substrate having a transparent electrode with stable resistivity against various environments is produced by a magnetron sputtering method using a target composed of a zinc oxide transparent electroconductive oxide containing 0.50 to 2.75% silicon dioxide by weight relative to the oxide.
US08895423B2 Method for making semiconductor diodes with low reverse bias currents
A diode is described with a III-N material structure, an electrically conductive channel in the III-N material structure, two terminals, wherein a first terminal is an anode adjacent to the III-N material structure and a second terminal is a cathode in ohmic contact with the electrically conductive channel, and a dielectric layer over at least a portion of the anode. The anode comprises a first metal layer adjacent to the III-N material structure, a second metal layer, and an intermediary electrically conductive structure between the first metal layer and the second metal layer. The intermediary electrically conductive structure reduces a shift in an on-voltage or reduces a shift in reverse bias current of the diode resulting from the inclusion of the dielectric layer. The diode can be a high voltage device and can have low reverse bias currents.
US08895416B2 Semiconductor device PN junction fabrication using optical processing of amorphous semiconductor material
Systems and methods for semiconductor device PN junction fabrication are provided. In one embodiment, a method for fabricating an electrical device having a P-N junction comprises: depositing a layer of amorphous semiconductor material onto a crystalline semiconductor base, wherein the crystalline semiconductor base comprises a crystalline phase of a same semiconductor as the amorphous layer; and growing the layer of amorphous semiconductor material into a layer of crystalline semiconductor material that is epitaxially matched to the lattice structure of the crystalline semiconductor base by applying an optical energy that penetrates at least the amorphous semiconductor material.
US08895415B1 Tensile stressed doped amorphous silicon
The method and apparatus disclosed herein relate to preparing a stack structure for an electronic device on a semiconductor substrate. A particularly beneficial application of the method is in reduction of internal stress in a stack containing multiple layers of silicon. Typically, though not necessarily, the internal stress is a compressive stress, which often manifests as wafer bow. In some embodiments, the method reduces the internal stress of a work piece by depositing phosphorus doped silicon layers having low internal compressive stress or even tensile stress. The method and apparatus disclosed herein can be used to reduce compressive bow in stacks containing silicon.
US08895413B2 Monolithic integration of photonics and electronics in CMOS processes
Methods and systems for monolithic integration of photonics and electronics in CMOS processes are disclosed and may include fabricating photonic and electronic devices on two CMOS wafers with different silicon layer thicknesses for the photonic and electronic devices bonded to at least a portion of each of the wafers together, where a first of the CMOS wafers includes the photonic devices and a second of the CMOS wafers includes the electronic devices. The electrical devices may be coupled to optical devices utilizing through-silicon vias. The different thicknesses may be fabricated utilizing a selective area growth process. Cladding layers may be fabricated utilizing oxygen implants and/or utilizing CMOS trench oxide on the CMOS wafers. Silicon may be deposited on the CMOS trench oxide utilizing epitaxial lateral overgrowth. Cladding layers may be fabricated utilizing selective backside etching. Reflective surfaces may be fabricated by depositing metal on the selectively etched regions.
US08895410B2 Method of manufacturing semiconductor device and semiconductor manufacturing apparatus
A cause of deteriorating the hydrogen termination on the surface of a wafer is found to be water adsorbed on the surface. By exposing the wafer to an inert gas atmosphere containing an H2 gas so as to suppress the oxidation reaction due to the water, it is possible to improve the hydrogen termination on the wafer surface.
US08895405B2 Method for manufacturing a semiconductor device
A method of manufacturing a semiconductor device includes forming a silicon nitride film having an opening portion on a semiconductor substrate, forming a silicon oxide film on the silicon nitride film and on a side face of the opening portion, performing an etching treatment to the silicon oxide film so that a sidewall is formed on the side face of the opening portion, forming a trench on the semiconductor substrate with use of the sidewall and the silicon nitride film as a mask, and forming an insulating layer in the trench. The step of forming the silicon oxide film includes oxidizing the silicon nitride film with a plasma oxidation method or a radical oxidation method.
US08895401B2 Method of forming a memory device incorporating a resistance variable chalcogenide element
A method of forming a memory device, such as a PCRAM, including selecting a chalcogenide glass backbone material for a resistance variable memory function and devices formed using such a method.
US08895398B2 Method for manufacturing double-gate structures
A method is provided for manufacturing a double-gate structure. The method includes providing a substrate and forming a first gate region on a surface of the substrate using a first gate layer. The method also includes forming a second gate layer on the surface of the substrate, wherein the second gate layer covers the first gate region, forming an etch-stop layer on the second gate layer, and forming a silicide layer on the etch-stop layer. The method also includes forming a second gate region, different from the first gate region, containing the second gate layer and the silicide layer without the etch-stop layer. Further, the etch-stop layer is arranged between the second gate layer and the silicide layer to facilitate even etching of the second gate layer around the first gate region.
US08895396B1 Epitaxial Process of forming stress inducing epitaxial layers in source and drain regions of PMOS and NMOS structures
An epitaxial process includes the following steps. A first gate and a second gate are formed on a substrate. Two first spacers are formed on the substrate beside the first gate and the second gate respectively. Two first epitaxial layers having first profiles are formed in the substrate beside the two first spacers respectively. A second spacer material is formed to cover the first gate and the second gate. The second spacer material covering the second gate is etched to form a second spacer on the substrate beside the second gate and expose the first epitaxial layer beside the second spacer while reserving the second spacer material covering the first gate. The exposed first epitaxial layer in the substrate beside the second spacer is replaced by a second epitaxial layer having a second profile different from the first profile.
US08895395B1 Reduced resistance SiGe FinFET devices and method of forming same
A method for forming a fin field-effect transistor (FinFET) device, comprises forming a plurality of silicon fins on a substrate, depositing silicon germanium (SiGe) on the plurality of fins, forming a gate region by forming a dummy gate stack on a predetermined area of the fins including the SiGe, removing the SiGe from an area of the fins not covered by the dummy gate stack, forming a merged region in the area of the fins not covered by the dummy gate stack to form a source drain region, removing the dummy gate stack to expose the remaining SiGe in the gate region, mixing the SiGe with the silicon fins in the gate region to form SiGe fins, and depositing a gate dielectric and gate metal on the SiGe fins.
US08895394B2 Trench FET with source recess etch
A high voltage vertical field effect transistor device (101) is fabricated in a substrate (102, 104) using angled implantations (116, 120) into trench sidewalls formed above recessed gate poly layers (114) to form self-aligned N+ regions (123) adjacent to the trenches and along an upper region of an elevated substrate. With a trench fill insulator layer (124) formed over the recessed gate poly layers (114), self-aligned P+ body contact regions (128) are implanted into the elevated substrate without counter-doping the self-aligned N+ regions (123), and a subsequent recess etch removes the elevated substrate, leaving self-aligned N+ source regions (135-142) and P+ body contact regions (130-134).
US08895388B2 Method of manufacturing a semiconductor device and a non-volatile semiconductor storage device including the formation of an insulating layer using a plasma treatment
An object is to provide a technique for manufacturing an insulating layer with favorable withstand voltage. Another object is to provide a technique for manufacturing a semiconductor device having an insulating layer with favorable withstand voltage. By subjecting a semiconductor layer or semiconductor substrate mainly containing silicon to a high density plasma treatment, an insulating layer is formed on a surface of the semiconductor layer or a top surface of the semiconductor substrate. At this time, the high density plasma treatment is performed by switching a supply gas in the middle of the treatment from a gas containing a rare gas, oxygen, and hydrogen, to a gas containing a rare gas and oxygen.
US08895387B2 Method of manufacturing nonvolatile semiconductor memory device
According to one embodiment, a method includes forming first and second gate patterns each including a structure stacked in order of a first insulating layer, a floating gate layer, a charge trap layer, a second insulating layer and a dummy layer on a semiconductor layer, implanting impurities in the semiconductor layer by an ion implantation using the first and second gate patterns as a mask, forming a third insulating layer on the semiconductor layer, the third insulating layer covering side surfaces of the first and second gate patterns, and forming first and second concave portions, the first concave portion formed by removing the dummy layer of the first gate pattern, the second concave portion formed by removing the dummy layer, the second insulating layer, the charge trap layer and the floating gate layer of the second gate pattern.
US08895383B2 Multiple-gate semiconductor device and method
A system and method for manufacturing multiple-gate semiconductor devices is disclosed. An embodiment comprises multiple fins, wherein intra-fin isolation regions extend into the substrate less than inter-fin isolation regions. Regions of the multiple fins not covered by the gate stack are removed and source/drain regions are formed from the substrate so as to avoid the formation of voids between the fins in the source/drain region.
US08895379B2 Integrated circuit having raised source drains devices with reduced silicide contact resistance and methods to fabricate same
A structure has at least one field effect transistor having a gate stack disposed between raised source drain structures that are adjacent to the gate stack. The gate stack and raised source drain structures are disposed on a surface of a semiconductor material. The structure further includes a layer of field dielectric overlying the gate stack and raised source drain structures and first contact metal and second contact metal extending through the layer of field dielectric. The first contact metal terminates in a first trench formed through a top surface of a first raised source drain structure, and the second contact metal terminates in a second trench formed through a top surface of a second raised source drain structure. Each trench has silicide formed on sidewalls and a bottom surface of at least a portion of the trench. Methods to fabricate the structure are also disclosed.
US08895373B2 Method for manufacturing flexible semiconductor device having gate electrode disposed within an opening of a resin film
There is provided a flexible semiconductor device. The flexible semiconductor device of the present invention comprising a support layer, a semiconductor structure portion formed on the support layer, and a resin film formed on the semiconductor structure portion. The resin film comprises an opening formed by a laser irradiation therein, and also an electroconductive member which is in contact with the surface of the semiconductor structure portion is disposed within the opening of the resin film.
US08895371B2 Transistor employing vertically stacked self-aligned carbon nanotubes
A fin structure including a vertical alternating stack of a first isoelectric point material layer having a first isoelectric point and a second isoelectric material layer having a second isoelectric point less than the first isoelectric point is formed. The first and second isoelectric point material layers become oppositely charged in a solution with a pH between the first and second isoelectric points. Negative electrical charges are imparted onto carbon nanotubes by an anionic surfactant to the solution. The electrostatic attraction causes the carbon nanotubes to be selectively attached to the surfaces of the first isoelectric point material layer. Carbon nanotubes are attached to the first isoelectric point material layer in self-alignment along horizontal lengthwise directions of the fin structure. A transistor can be formed, which employs a plurality of vertically aligned horizontal carbon nanotubes as the channel.
US08895366B2 Fabrication method of semiconductor package
A semiconductor package and a fabrication method thereof are disclosed. The fabrication method includes the steps of providing a semiconductor chip having an active surface and a non-active surface opposing to the active surface, roughening a peripheral portion of the non-active surface so as to divide the non-active surface into the peripheral portion formed with a roughened structure and a non-roughened central portion, mounting the semiconductor chip on a chip carrier via a plurality of solder bumps formed on the active surface, forming an encapsulant on the chip carrier to encapsulate the semiconductor chip. The roughened structure formed on the peripheral portion of the non-active surface of the semiconductor chip can reinforce the bonding between the semiconductor chip and the encapsulant, and the non-roughened central portion of the non-active surface of the semiconductor chip can maintain the structural strength of the semiconductor chip.
US08895354B2 Method of forming organic semiconductor device that includes forming electrode contact layer by treating electrode surfaces with substance containing substituted arene
Method for producing a semiconductor device such as an organic thin film transistor, and a device produced by the method, the method including the steps of forming conducting electrodes over a substrate, treating a surface of the electrodes with an arene substituted with an electron-withdrawing group to form an electrode contact layer over the electrodes, and forming an organic semiconductor layer over the substrate and electrodes, in which the substrate and electrodes are baked before the organic semiconductor layer is formed so as to reduce contaminants on the electrode contact layer and thereby promote improved crystal nucleation on a surface of the electrode.
US08895353B2 Cationic conjugated polyelectrolyte electron injection layers altered with counter anions having oxidative properties
Counter anions having oxidative properties alter the performance of solution processed multilayer polymer light emitting diodes (PLEDs) that use cationic conjugated polyelectrolytes (CPEs) as electron injection layers (EILs). In some versions, PLEDs with poly(2-methoxy-5-(2′-ethylhexyloxy)-1,4-phenylene vinylene) (MEH-PPV) emissive layers and cationic CPE EILs are altered with halide counter anions to exhibit a systematic increase in device performance. Exemplary oxidative counter anions are halide counter anions with F−>Cl−>Br−>I− in terms of device performance.
US08895351B2 Method and apparatus of forming a conductive layer
The present invention generally includes an apparatus and process of forming a conductive layer on a surface of a host substrate, which can be directly used to form a portion of an electronic device. More specifically, one or more of the embodiments disclosed herein include a process of forming a conductive layer on a surface of a substrate using an electrospinning type deposition process. Embodiments of the conductive layer forming process described herein can be used to reduce the number of processing steps required to form the conductive layer, improve the electrical properties of the formed conductive layer and reduce the conductive layer formation process complexity over current state-of-the-art conductive layer formation techniques. Typical electronic device formation processes that can benefit from one or more of the embodiments described herein include, but are not limited to processes used to form solar cells, electronic visual display devices and touchscreen type technologies.
US08895350B2 Methods for forming nanostructures and photovoltaic cells implementing same
A method for forming a nanostructure according to one embodiment includes creating a hole in an insulating layer positioned over an electrically conductive layer; and forming a nanocable in the hole such that the nanocable extends through the hole in the insulating layer and protrudes therefrom, the nanocable being in communication with the electrically conductive layer. Additional systems and methods are also presented.
US08895343B2 High density capacitor integrated into focal plane array processing flow
Methods and structures of photodetectors are described. The structure may include a readout integrated circuit substrate having an internally integrated capacitor. The structure may additionally include an external capacitor overlying the readout integrated circuit substrate. The external capacitor may be coupled with the internally integrated capacitor of the readout integrated circuit substrate, and configured to operate in parallel with the internally integrated capacitor of the readout integrated circuit substrate. The structure may also include a detector overlying the external capacitor.
US08895342B2 Heterojunction subcells in inverted metamorphic multijunction solar cells
Inverted metamorphic multijunction solar cells having a heterojunction middle subcell and a graded interlayer, and methods of making same, are disclosed herein. The present disclosure provides a method of manufacturing a solar cell using an MOCVD process, wherein the graded interlayer is composed of (InxGa1-x)yAl1-yAs, and is formed in the MOCVD reactor so that it is compositionally graded to lattice match the middle second subcell on one side and the lower third subcell on the other side, with the values for x and y computed and the composition of the graded interlayer determined so that as the layer is grown in the MOCVD reactor, the band gap of the graded interlayer remains constant at 1.5 eV throughout the thickness of the graded interlayer.
US08895340B1 Biosensor and system and process for forming
A process for forming a carbon nanotube field effect transistor (CNTFET) device includes site-specific nanoparticle deposition on a CNTFET that has one or more carbon nanotubes, a source electrode, a drain electrode, and a sacrificial electrode on a substrate with an interposed dielectric layer. The process includes control of PMMA removal and electrodeposition in order to select nanoparticle size and deposition location down to singular nanoparticle deposition. The CNTFET device resulting in ultra-sensitivity for various bio-sensing applications, including detection of glucose at hypoglycemic levels.
US08895333B2 Method for manufacturing semiconductor device with pixel electrode over gate electrode of thin film transistor
The number of photomasks is reduced in a method for manufacturing a liquid crystal display device which operates in a fringe field switching mode, whereby a manufacturing process is simplified and manufacturing cost is reduced. A first transparent conductive film and a first metal film are sequentially stacked over a light-transmitting insulating substrate; the first transparent conductive film and the first metal film are shaped using a multi-tone mask which is a first photomask; an insulating film, a first semiconductor film, a second semiconductor film, and a second metal film are sequentially stacked; the second metal film and the second semiconductor film are shaped using a multi-tone mask which is a second photomask; a protective film is formed; the protective film is shaped using a third photomask; a second transparent conductive film is formed; and the second transparent conductive film is shaped using a fourth photomask.
US08895327B1 Tipless transistors, short-tip transistors, and methods and circuits therefor
An integrated circuit can include a plurality of first transistors formed in a substrate and having gate lengths of less than one micron; and at least one tipless transistor formed in the substrate and having a source-drain path coupled between a circuit node and a first power supply voltage; wherein at least one tipless transistor has source and drain vertical doping profiles without extension regions that extend in a lateral direction under a gate electrode. In addition or alternatively, an integrated circuit can include minimum feature size transistors having gate lengths of less than one micron; a signal driving circuit comprising a first transistor of a first conductivity type having a source-drain path coupled between a first power supply node and an output node, and a second transistor of a second conductivity type having a source-drain path coupled between a second power supply node and the output node, and a gate coupled to a gate of the first transistor, wherein at least one of the first or second transistor is a tipless transistor having source and drain vertical doping profiles without extension regions that extend in a lateral direction under a gate electrode.
US08895326B2 Method of attaching wafer to sheet
A wafer attaching method of attaching a wafer having a warp to a sheet includes a wafer warp detecting step of detecting a surface shape of the wafer, a wafer positioning step of applying a photocuring liquid resin to the sheet and positioning the wafer so that a predetermined surface of the wafer corresponding to attaching conditions preset in a resin bonding apparatus is opposed to the sheet and the liquid resin according to the preset attaching conditions and the surface shape detected above, and a wafer attaching step of pressing the wafer against the liquid resin to thereby spread the liquid resin over the entire area where the wafer and the sheet are superimposed, next removing the pressure applied to the wafer, and next applying light to the liquid resin to cure the liquid resin, thereby attaching the predetermined surface of the wafer to the sheet.
US08895323B2 Method of forming a magnetoresistive random-access memory device
A method for forming MRAM (magnetoresistive random access memory) devices is provided. A bottom electrode assembly is formed. A magnetic junction assembly is formed, comprising, depositing a magnetic junction assembly layer over the bottom electrode assembly, forming a patterned mask over the magnetic junction assembly layer, etching the magnetic junction assembly layer to form the magnetic junction assembly with gaps, gap filling the magnetic junction assembly, and planarizing the magnetic junction assembly. A top electrode assembly is formed.
US08895322B2 Method for making semiconductor device having ferroelectric capacitor therein
A ferroelectric capacitor provided with a ferroelectric film (10a) is formed above a semiconductor substrate, and thereafter a wiring (17) directly connected to electrodes (9a, 11a) of a ferroelectric capacitor is formed. Then, a silicon oxide film (18) covering the wiring (17) is formed. As the silicon oxide film (18), a film which has processability higher than that of an aluminum oxide film is formed. Besides, a degree of damage that occurs in the ferroelectric capacitor when the insulating film is formed is equal to or less than that when an aluminum oxide film is formed.
US08895318B2 Ammonia compound concentration measuring device and ammonia compound concentration measuring method
An ammonia compound concentration measuring device includes: a pipe unit through which the circulating gas flows; a converter which is disposed in the pipe unit and converts an ammonia compound into ammonia; a measurement device which measures a first measurement value as a concentration of ammonia contained in a first circulating gas flowing inside a pipe line passing through the converter in the circulating gas flowing inside the pipe unit and a second measurement value as a concentration of ammonia contained in a second circulating gas flowing inside a pipe line not passing through the converter in the circulating gas flowing inside the pipe unit; and a controller which controls operations of the pipe unit and the measurement device and calculates the concentration of the ammonia compound of the measurement subject contained in the circulating gas from a difference between the first measurement value and the second measurement value.
US08895317B2 Reagent for measuring active nitrogen
A compound represented by the general formula (I) [R1 and R2 are amino groups that substitute at adjacent positions on the benzene ring; R3 and R4 are halogen atoms; R5 and R6 represent hydrogen atom, an acyl group or an acyloxy(C1-6 alkyl) group; R7 and R8 represent —(CH2)p—N(R9)(R10) (p is 1 to 4, and R9 and R10 represent —(CH2)n—COOH (n is 1 to 4))], which is useful for measuring a reactive nitrogen species existing in cells such as nitrogen monoxide or peroxynitrite at high sensitivity over a long period of time.
US08895313B2 Ligands for aggregated tau molecules
Provided are certain benzothiazole, imidazothiazole, imidazopyrimidine and imidazopyridine compounds, including, for example: formula (I) and pharmaceutically and physiologically acceptable salts, hydrates, and solvates thereof. Such compounds can be used as diagnostic ligands or labels of tau protein and PHF.
US08895310B2 L-rhamnose-inducible expression systems
The present invention relates to methods for expressing nucleic acid sequences in prokaryotic host cells, where at least one DNA construct which is capable of episomal replication in a host cell and which comprises a nucleic acid sequence to be expressed under the transcriptional control of an L-rhamnose-inducible promoter, where the promoter is heterologous with regard to the nucleic acid sequence, is introduced into the host cell and the expression of he nucleic acid sequence is induced by addition of L-rhamnose, wherein the prokaryotic host cell is at least deficient with regard to an L-rhamnose isomerase.
US08895308B1 Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation
The invention provides for engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are compositions and methods related to components of a CRISPR complex particularly comprising a Cas ortholog enzyme.
US08895305B2 Water deficit-inducible promoters
Water deficit-inducible promoter sequences were identified that may be used to produce transgenic plants that are more tolerant to water deficit and related hyperosmotic stresses than control plants, and yet are wild-type or nearly wild type in appearance. Any of these water deficit-inducible promoters may be incorporated into an expression vector that comprises a polynucleotide regulated by one such promoter and which encodes a polypeptide that, when ectopically expressed, improves water deficit tolerance in plants that are similar to control plants in their morphology and development.
US08895304B2 Hemostatic device
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
US08895303B2 Method of cell culture and method of treatment comprising a vEPO protein variant
In one aspect the present invention is concerned with a method of cell culture, comprising the steps of (i) obtaining a stem or progenitor cell sample, (ii) culturing the stem or progenitor cell sample in media and under closed conditions appropriate to cause proliferation or differentiation of the stem or progenitor cells, wherein the media comprises a vEPO protein variant, (iii) purifying the stem or progenitor cells ex vivo. The invention relates to a method of increasing the number and survival of stem and progenitor cells in vitro and in vivo using a vEPO protein variant. The invention also relates to improved differentiation of stem and progenitor cells in vitro and in vivo using a vEPO protein variant.
US08895301B2 Exogenous Pax6 nucleic acid expression in primate neural stem cells maintains proliferation without differentiation
A transcription factor both necessary and sufficient for human neuroectoderm specification, Pax6, as well as applications thereof, is disclosed.
US08895300B2 Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof
The present invention relates to methods for production of undifferentiated or differentiated embryonic stem cell aggregate suspension cultures from undifferentiated or differentiated embryonic stem cell single cell suspensions and methods of differentiation thereof.
US08895293B2 Assay device having uniform flow around corners
An assay device includes: a liquid sample zone; a reagent zone downstream and in fluid communication with the sample zone containing a reagent material; a detection zone in fluid communication with the reagent zone having capture elements bound thereto; and a wicking zone in fluid communication with the capture zone having a capacity to receive liquid sample flowing from the detection zone. The sample receiving zone, the reagent zone, the detection zone and the wicking zone define a fluid flow path and at least a part of the fluid flow path has a substrate and projections which extend substantially vertically from the substrate, wherein the projections have a height, cross-section and a distance between one another that defines a space between the projections capable of generating capillary flow parallel to the substrate surface. In addition, the fluid flow path having projections includes a corner section which changes the direction of the flow path. The projections in or around the corner section are modified to maintain the configuration of the flow front of the sample flowing through the flow path after the corner is substantially the same configuration as before the corner.
US08895292B2 Microfluidic chip devices and their use
A microfluidic chip device (MCD) and its use for performing miniaturized assays on magnetic microbeads (MMs) are described. The MCD is particularly useful for carrying out miniaturized transcript analysis by aiding affinity capturing (TRAC) assays, including PCR. The MCD comprises at least one reaction chamber with sealable liquid connections and at least one fluidic pillar filter in each chamber. The fluidic pillar filter comprises rods with spacings allowing MMs to pass. The sealable liquid connections feed liquid to the reaction chamber, wherein air bubbles are removed. The liquid stream contacts the MMs, which are manipulated with a magnetic rod. The liquid connections enable trapping of the MMs behind the pillar filters or in the channel, while the liquid is changed.
US08895291B2 Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
Embodiments described herein generally relate to methods and systems for using an air removal chamber as a control for a process in a cell expansion system. The air removal chamber may be mounted on a fluid conveyance assembly for use with the system. Fluid is pumped into a fluid containment chamber of the air removal chamber, in which the level of fluid in the fluid containment chamber may be monitored through the use of one or more sensors. The sensors are capable of detecting air, a lack of fluid, fluid, and/or a gas/fluid interface, e.g., an air/fluid interface, at measuring positions within the air removal chamber. Protocols for use with the system may include one or more stop conditions. In an embodiment, the stopping of a process is automated based on the detection of air, a lack of fluid, and/or a gas/fluid interface in the air removal chamber.
US08895287B2 Metabolically engineered cells for the production of resveratrol or an oligomeric or glycosidically-bound derivative thereof
A recombinant micro-organism producing resveratrol by a pathway in which phenylalanine ammonia lyase (PAL) produces trans-cinnamic acid from phenylalanine, cinnamate 4-hydroxylase (C4H) produces 4-coumaric acid from said trans-cinnamic acid, 4-coumarate-CoA ligase (4CL) produces 4-coumaroyl CoA from said 4-coumaric acid, and resveratrol synthase (VST) produces said resveratrol from said 4-coumaroyl CoA, or in which L-phenylalanine- or tyrosine-ammonia lyase (PAL/TAL) produces 4-coumaric acid, 4-coumarate-CoA ligase (4CL) produces 4-coumaroyl CoA from said 4-coumaric acid, and resveratrol synthase (VST) produces said resveratrol from said 4-coumaroyl CoA. The micro-organism may be a yeast, fungus or bacterium including Saccharomyces cerevisiae, E. coli, Lactococcus lactis, Aspergillus niger, or Aspergillus oryzae.
US08895285B2 Modified ethylenediamine-N, N′-disuccinate: ethylenediamine lyase
The present invention provides a modified ethylenediamine-N,N′-disuccinate:ethylenediamine lyase. The present invention also provides a protein that comprises the amino acid sequence represented by SEQ ID NO: 1; or a protein that comprises an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 1 by deletion, substitution, or addition of one or more amino acid residues, and has an ethylenediamine-N,N′-disuccinate:ethylenediamine lyase activity.
US08895280B2 Polysilicate-polysilicone enzyme immobilization materials
The present invention generally relates to improvements in enzyme immobilization, particularly for use in the field of carbon dioxide capture and sequestering. It has been discovered that the utilization of sol-gel processes to immobilize enzymes in polysilicate-polysilicone copolymer coatings and particles, and the deposition of these coatings on solid state supports or use of suspensions of these particles, provides significant benefits for use in industrial applications involving enzymatic catalysts.
US08895273B2 Conversion of hexuronic acid to hexaric acid
The present invention relates to a method and microbial host strain for converting a hexuronic acid to a hexaric acid. In particular, the invention relates to the conversion of D-galacturonic acid to meso-galactaric acid (mucic acid). The invention also concerns an isolated nucleotide sequence. According to the present method a microbial host strain genetically modified to express uronate dehydrogenase enzyme (EC 1.1.1.203) is contacted with a biomaterial comprising hexuronic acid and the conversion products are recovered. By using the recombinant microorganisms of the present invention it is possible to treat biomaterials comprising hexuronic acids and thereby decrease the amount of hexuronic acids released to the environment.
US08895271B2 Synthesis of prazole compounds
The present disclosure relates to non-naturally occurring monooxygenase polypeptides useful for preparing prazole compounds, polynucleotides encoding the polypeptides, and methods of using the polypeptides.
US08895261B2 Use of fluorescent saccharide-based derivative
The disclosure provides a use of a fluorescent saccharide-based derivative in cell detection. The fluorescent saccharide-based derivative is obtained from a reactive material through an imine formation reaction, and the reactive material is selected from a composition (A) or a composition (B). The composition (A) includes a reducing sugar compound and an amino group-containing compound having at least one primary amino group. The composition (B) includes an amino sugar compound and a carbonyl group-containing compound, and the amino sugar compound contains at least one primary amino group.
US08895259B2 Method for determination of platelet function under flow conditions
The invention lies in the area of platelet function diagnostics and relates to an in vitro method for the determination of platelet function under flow conditions. The method is particularly suitable for the determination of the effect of clopidogrel after oral intake and of other P2Y(12) antagonists with antithrombotic activity as well as the determination of P2Y(1) receptor antagonists with antithrombotic activity.
US08895258B2 Device for measuring proteins using biosensor
A sensor for measuring a concentration of a specific protein using a biosensor with a measurement speed improved from a conventional impedance measurement. The sensor is capable of efficiently and accurately measuring impedance generated by a selective binding to the protein by Fourier-transforming an electric current signal obtained by applying a potential signal of a delta function waveform. The device for measuring a protein using a biosensor is capable of measuring concentration of the protein with accuracy, measurement time is shortened and the concentration of protein can be accurately measured by removing the influence of dispersion.
US08895257B2 Proteins used for the diagnosis of lyme borreliosis
Chimera proteins including: (i) at least one sequence of a VlsE protein of a Borrelia species selected from B. garinii, B. burgdorferi sensu stricto and B. afzelii, and (ii) at least one sequence including sequences of the IR6 domain of B. burgdorferi sensu stricto, B. afzelii and B. garinii. Also, a method and a kit for the in vitro diagnosis of Lyme borreliosis using said proteins.
US08895255B1 Sensitive and rapid determination of antimicrobial susceptibility
The present invention relates to moving microorganisms to a surface, where they are grown in the presence and absence of antimicrobials, and by monitoring the growth of the microorganisms over time in the two conditions, their susceptibility to the antimicrobials can be determined. The microorganisms can be moved to the surface through electrophoresis, centrifugation or filtration. When the movement involves electrophoresis, the presence of oxidizing and reducing reagents lowers the voltage at which electrophoretic force can be generated and allows a broader range of means by which the target can be detected. Monitoring can comprise optical detection, and most conveniently includes the detection of individual microorganisms. The microorganisms can be stained in order to give information about their response to antimicrobials.
US08895253B2 Integrin heterodimer and a subunit thereof
A recombinant or isolated integrin heterodimer comprising a novel subunit α10 in association with a subunit β is described. The α10 integrin may be purified from bovine chondrocytes on a collagen-type-II affinity column. The integrin or the subunit of α10 can be used as a marker or target of all types of cells, e.g. of chondrocytes, osteoblasts, and fibroblasts. The integrin or the subunit α10 thereof can be used as a marker or target in different physiological or therapeutic methods. They can also be used as active ingredients in pharmaceutical compositions and vaccines.
US08895252B2 High energy radiation insensitive analyte sensors
Enzyme based analyte sensors having radiation stabilizing agents are disclosed and described. More particularly, devices comprising a radiation stabilizing agent and methods for stabilizing sensors to high energy radiation sterilization are disclosed and described.
US08895249B2 Kinetic exclusion amplification of nucleic acid libraries
A method including (a) providing an amplification reagent including an array of sites, and a solution having different target nucleic acids; and (b) reacting the amplification reagent to produce amplification sites each having a clonal population of amplicons from a target nucleic acid from the solution. The reacting can include simultaneously transporting the nucleic acids to the sites at an average transport rate, and amplifying the nucleic acids that transport to the sites at an average amplification rate, wherein the average amplification rate exceeds the average transport rate. The reacting can include producing a first amplicon from a nucleic acid that transports to each of the sites, and producing subsequent amplicons from the nucleic acid or from the first amplicon, wherein the average rate at which the subsequent amplicons are generated exceeds the average rate at which the first amplicon is generated.
US08895248B1 Method for detecting Salmonella species by assaying outer membrane Porin F (ompF)
The invention relates to a method of detecting the presence of Salmonella in a sample using novel oligonucleotide sequences. Also presented is a kit for putting the method into practice and novel nucleic acid sequences for ompF. The ompF gene was found to be 100% inclusive for Salmonella species and 100% exclusive for non-Salmonella species for the strains tested thus making it an excellent marker for identification of both the species of Salmonella: S. enterica and S. bongori. Two hundred and eighteen isolates belonging to Salmonella enterica (subspecies I-VI) and Salmonella bongori were examined using novel primers designed to detect the ompF gene. The target was present in all the 218 Salmonella isolates including all the subspecies of Salm. enterica and Salm. bongori. The ompF gene was absent in 180 non-Salmonella strains tested.
US08895247B2 Method for detection of human papillomavirus (HPV) type
The present invention describes a method for detection of human papillomavirus (HPV) types and a kit for detection of said HPV types.
US08895246B2 Nucleic acid detection method
This invention provides a novel method for amplifying and detecting a target gene rapidly with high sensitivity under isothermal conditions. In such method, a sequence to be amplified can be freely designed regardless of the template sequence, an amplified product can be amplified and detected within a short period of time with high sensitivity, and thus, the gene expression level can be determined more easily than is possible with prior art.
US08895239B2 Genetically engineered biological indicator
The disclosed technology relates to a genetically engineered biological indicator, comprising: at least one test organism and at least one reporter gene suitable for producing an indicator enzyme, the reporter gene being taken up by the test organism; and at least one repressor gene that inhibits expression of the reporter gene until the reporter gene is exposed to at least one inducer. A process and an apparatus for using the biological indicator are disclosed.
US08895234B2 Immersion lithography watermark reduction
Provided is a method of performing a lithography process. The method includes: exposing, through an immersion lithography process, a photo-sensitive material on a substrate, the immersion lithography process using a fluid for the exposing; thereafter treating the photo-sensitive material with a solution to neutralize quenchers that have diffused into the photo-sensitive material through the liquid, wherein the solution contains a substance that diffuses into the photo-sensitive material at a first rate that is dependent on a second at which the quenchers diffuse into the photo-sensitive material; thereafter removing a portion of the photo-sensitive material; thereafter performing a post-exposure bake to the photo-sensitive material; and developing the photo-sensitive material.
US08895231B2 Patterning process and resist composition
A pattern is formed by coating a first positive resist composition comprising a base resin, a photoacid generator, and a base generator having both a 9-fluorenylmethyloxycarbonyl-substituted amino group and a carboxyl group onto a substrate to form a first resist film, patternwise exposure, PEB, and development to form a first resist pattern, heating the first resist pattern for causing the base generator to generate a base for inactivating the pattern to acid, coating a second positive resist composition comprising an alcohol and an optional ether onto the first resist pattern-bearing substrate to form a second resist film, patternwise exposure, PEB, and development to form a second resist pattern.
US08895224B2 Lithographic printing plate precursors and processes for preparing lithographic printing plates
Lithographic printing plates and processes for preparing the lithographic printing plates are provided. The plates have excellent printing durability, staining resistance and staining resistance over time. The lithographic printing plate precursor includes: a substrate; a photosensitive layer provided on the substrate; and an extra layer optionally provided between the substrate and the photosensitive layer. The photosensitive layer or the extra layer adjacent to the substrate contains (A) a copolymer. The copolymer (A) includes: (a1) a repeating unit of formula (a1-1) below in a side chain, and (a2) a repeating unit having at least one of the structures represented by formulae (a2-1) to (a2-6) shown in the specification in a side chain. L1, Z1, R1, and R21, R22 and R23 in formula (a1-1) and the variables in formulae (a2-1) to (a2-6) are as defined in the specification.
US08895221B2 Thermal image receiver elements prepared using aqueous formulations
A thermal image receiver element dry image receiving layer has a Tg of at least 25° C. as the outermost layer. The dry image receiving layer has a dry thickness of at least 0.5 μm and up to and including 5 μm. It comprises a polymer binder matrix that consists essentially of: (1) a water-dispersible acrylic polymer comprising chemically reacted or chemically non-reacted hydroxyl, phospho, phosphonate, sulfo, sulfonate, carboxy, or carboxylate groups, and (2) a water-dispersible polyester that has a Tg of 30° C. or less. The water-dispersible acrylic polymer is present in an amount of at least 55 weight % of the total dry image receiving layer weight and at a dry ratio to the water-dispersible polyester of at least 1:1 to and including 20:1. The thermal image receiver element can be used to prepare thermal dye images after thermal transfer from a thermal donor element.
US08895208B2 Manufacture and calibration process for an interconnect for a fuel cell or a cell stack
The manufacture and calibration of an interconnect for a fuel cell ensures contact in all contact points between the interconnect and the adjacent electrodes.
US08895194B2 Solid electrolyte material of conducting lithium ion, battery device using the solid electrolyte material and all-solid lithium secondary battery provided with the battery device
A solid electrolyte material of conducting a lithium ion comprises a sulfide-based lithium-ion conductor and α-alumina. Such a solid electrolyte material exhibits superior lithium-ion conductivity. Further, a battery device provided with such a solid electrolyte material is also provided. Furthermore, an all-solid lithium-ion secondary battery provided with such a battery device is also provided.
US08895183B2 External terminal assembly including a terminal holder coupled to a protection circuit substrate and battery pack including the same
An external terminal assembly for establishing a connection between a battery pack and an electrical connector of an external device and a battery pack including the same, the external terminal assembly including an external terminal, the external terminal being electrically connectable to the electrical connector of the external device; a terminal holder on a protection circuit substrate, the terminal holder fixing a position of the external terminal; and a top case covering the protection circuit substrate and the terminal holder, the top case including holes exposing the external terminal.
US08895182B2 Battery pack and power tool provided with the same
According to an aspect of the present invention, there is provided a battery pack to be inserted and attached to a power tool, including: a case; a battery cell accommodated inside the case; and an electrode terminal connected to the battery cell and provided on the case so as to be connectable to a tool-side electrode terminal, wherein the case includes: a case main portion; and a case sub portion which is protruded from the case main portion to be inserted into the power tool, and wherein the electrode terminal is provided on an upper surface of the case main portion at a side of the case sub portion.
US08895181B2 Battery module
Provided is a battery module that offsets external power exerted on a rechargeable battery not only to protect the rechargeable battery but also to ensure security. The battery module includes: a casing which comprises an electrode assembly and has an open upper portion; a cap assembly which is disposed at an upper portion of the casing so as to seal the casing; and a first connection cap which is disposed on the cap assembly, wherein the first connection cap includes: a cap base which is fixed to the cap assembly and in which one or more indentations are formed at an outermost edge portion thereof; and a cover which protrudes from the cap base in an opposite direction of the cap assembly and has one or more openings at a lateral portion thereof.
US08895175B2 Intercellular separation structure body and laminate type solid secondary battery provided with the same
An intercellular separation structure body capable of electrically connecting a plurality of unit cells that include a laminate type solid secondary battery with each other, and capable of ion-conductively insulating a positive electrode layer and a negative electrode layer in two adjacent unit cells, as well as a laminate type solid secondary battery provided with the same. The intercellular separation structure body is an intercellular separation structure body disposed between a plurality of unit cells each of which includes a positive electrode layer, a solid electrolyte layer, and a negative electrode layer that are sequentially stacked in a laminate type solid secondary battery. This intercellular separation structure body includes an insulating layer that electroconductively and ion-conductively insulates the plurality of unit cells from each other and an electroconductive section that is formed within the insulating layer and electrically connects the plurality of unit cells with each other.
US08895174B2 Cable-type secondary battery
A cable-type secondary battery is provided. The cable-type secondary battery includes an electrode assembly and a covering capable of surrounding the electrode assembly. The electrode assembly includes a first polarity electrode, a second polarity electrode, and a separator or an electrolyte layer interposed between the two electrodes. Each of the electrodes has an elongated shape and a structure in which an electrode active material is applied to the surface of a current collector whose shape in cross section orthogonal to the lengthwise direction thereof is circular, elliptical or polygonal. The covering includes a thermally conductive cover member as an upper half part and a thermally insulating cover member as a lower half part. The upper half part and the lower half part are divided by a horizontal plane passing the center of the cross section orthogonal to the lengthwise direction of the cable-type secondary battery.
US08895173B2 Battery module for an electric vehicle, and method of assembly thereof
A battery module for an electric vehicle includes an auxiliary power module (APM) and at least one battery pack assembly. The battery pack assembly includes a plurality of battery frames, each with at least one battery cell disposed within it, and a plurality of cooling plates, each in thermal communication with at least one battery cell. The cooling plates have an inlet and an outlet connected by at least one coolant channel through which coolant is circulated to cool the battery cells. The APM may also require cooling, in which case the battery module may further include at least one additional cooling plate in thermal communication with the APM. The APM and the battery pack assembly are held together under compression such that they may share a common cooling system, and coolant may flow through the APM and/or the battery pack assembly to the cooling plates.
US08895164B2 Perpendicular magnetic recording medium
A perpendicular magnetic recording medium, which includes a nonmagnetic substrate, and a first underlayer in the form of a soft magnetic under-layer (SUL), a second underlayer, an intermediate layer, a magnetic recording layer, a protective layer, and a lubricant layer sequentially laminated on the nonmagnetic substrate. The SUL has a plurality of SUL layers including a type-A SUL layer, a plurality of type-B SUL layers including at least two adjacent type-B SUL layers, and a nonmagnetic metal spacer layer disposed between the two adjacent type-B SUL layers. The type-A SUL layer may include a material selected from Co, Fe and Ni, a material selected from Cr, V and Ti, and a material selected from W, Zr, Ta and Nb. Each of the type-B SUL layers is in antiferromagnetic coupling, and may include a material selected from Co, Fe and Ni, a material selected from Cr, V and Ti, and a material selected from W, Zr, Ta and Nb.
US08895163B2 Perpendicular magnetic recording medium
In a perpendicular magnetic recording medium having, over a substrate, a magnetic recording layer, an underlayer made of Ru or a Ru compound and provided below the magnetic recording layer, a pre-underlayer made of a nonmagnetic crystalline material, and a soft magnetic layer provided below the pre-underlayer, when the difference between the highest point and the lowest point of unevenness of the interface between the soft magnetic layer and the pre-underlayer, derived by a cross-sectional TEM image, is given as an interface roughness (nm) and the distance between the soft magnetic layer and the magnetic recording layer, excluding the soft magnetic layer and the magnetic recording layer, is given as a SUL-MAG distance (nm), interface roughness (nm)≦0.4 (nm) and interface roughness×SUL-MAG distance (nm)≦12 (nm) are satisfied.
US08895160B2 Product and method for its manufacture within material processing
The present invention provides an appliance for chip removal applications comprising a vibration-damping material wherein the vibration-damping material is a material arranged by nano-dimensional cluster form. The present invention additionally provides a method for manufacturing said appliance. The present invention provides also an appliance obtainable by said method. Additionally the present invention provides an article or work piece for use in an appliance for chip removal applications. Also a computer program is provided for controlling the above method.
US08895157B2 Host material for lighting devices
Optionally substituted bispyridinylbenzene compounds useful in light-emitting devices include, but are not limited to, 1,3-bis(5-(9H-carbazol-9-yl)pyridin-3-yl)benzene and 9,9′-(5,5′-(5-methyl-1,3-phenylene)bis(pyridine-5,3-diyl))bis(9H-carbazole).
US08895154B2 Organic electroluminescent device
Provided is an organic electroluminescent device in which an organic thin film layer comprising a single layer or plural layers comprising a phosphorescence light-emitting layer containing at least a host material and a phosphorescent organic metal complex is interposed between a cathode and an anode, wherein the total of the halogen element mass concentrations of bromine, iodine and chlorine which are contained as impurities in the host material constituting the light-emitting layer described above is 50 ppm or less. It has a high emission luminance, a high luminous efficiency and a long life.
US08895153B2 Chemical conversion coated plated steel sheet and method for producing same
Disclosed is a chemical conversion coated Al-plated steel sheet which has excellent weather resistance, water resistance and coating film adhesion. Specifically, a chemical conversion coating liquid is applied over and dried on the surface of an Al alloy-plated steel sheet, thereby forming a chemical conversion coating film that has a film thickness of 0.5-10 μm. The chemical conversion coating liquid contains: a fluorine-containing olefin resin, which contains 7-20% by mass of F atoms and 0.05-5% by mass of hydrophilic functional groups that are selected from among a carboxyl group, a sulfonic acid group and salts of carboxyl group and sulfonic acid group and has a number average molecular weight within the range of 1,000-2,000,000; and an oxygen acid salt, fluoride, hydroxide, organic acid salt, carbonate or peroxygenated salt of a group 4A metal.
US08895144B2 Multifunctional thermal conducting and/or radiating particles and array having the same, and fabrication method thereof
Disclosed are a multifunctional thermal conducting and/or radiating particle simultaneously having at least one of various functions, such as electromagnetic wave absorbing property, flame retardency, antistatic property, insulating property, thermal resistance and electrical conductivity, as well as a thermal conductivity, a composite array having the same and a fabrication method thereof. The multifunctional thermal conducting and/or radiating particle is composed of a core and a shell, wherein the core includes a core particle having a lower thermal conductivity than that of a particle included in the shell, and the shell includes high-thermal conductive particles each having a higher thermal conductivity than that of the core particle.
US08895142B2 High surface area and low structure carbon blacks for energy storage applications
The present invention, in part, relates to a carbon black having a) a nitrogen BET surface area (BET) of from about 600 m2/g to about 2100 m2/g, b) a CDBP value in mL/100 g of from about (−2.8+(b*BET)) to about (108+(b*BET)), where b is 0.087 and BET is expressed in m2/g, and c) an apparent density (p, g/cm3) of at least about 0.820+q*BET, where q=−2.5×10−4, as determined at a compressive force (P) of 200 kgf/cm2 on dry carbon black powder. Energy storage devices, such as electrochemical double layer capacitors (EDLC's), containing the carbon black are also disclosed. Methods for making the carbon blacks and EDLC's made with them are also provided.
US08895139B2 Isotropic nano crystallites of polytetrafluoroethylene (PTFE) resin and products thereof that are biaxially planar oriented and form stable
The subject invention concerns the use of staple length nano polytetrafluoroethylene (PTFE) crystallites obtained by liquid shearing PTFE dispersion particles that are wet by a liquid with a surface tension below 30 dynes/cm this liquid will spread on PTFE resin surfaces and has a contact angle of zero (0) degrees with a PTFE surface. Staple length PTFE resin micro-fibers will form rapidly under high liquid shearing force at 125° C. when diluted 1 part PTFE resin to 20 parts liquid. The subject invention also includes the application of products that are multi-directional planar oriented and isotropic as sheet, membranes and structures useful for high performance filtering, fuel and solar cells and related energy applications. It also concerns products made from formulations as coatings and product for forming, shaping and molding sheet and structures of the subject invention and methods of adhering, bond and laminating components of these structures without adhesives.
US08895133B2 Method of forming a coating on a surface of a substrate
A reinforcing underlayment including dry uniform particles evenly applied to a wet bonding material layer on a surface of a substrate. The substrate, including the layers, is then cured to harden the one or more of the layers. A final coating or topcoat is applied to the cured surface of the substrate. The dry particles are evenly distributed onto the bonding material layer creating a uniform surface for subsequent coatings. The dry particles increase the strength of the liquid coatings increasing solid particle density within the coating system and thereby imparting properties not available for the liquid coatings. The present invention enables a user to easily introduce very heavy, dense, strong particles into a liquid coating and allows the user to apply very dense, heavy particles into and onto a wet bonding material layer followed by a subsequent wet topcoat layer which is cured as one contiguous material with reinforcement and underlayment strengthening coming from the added, dry particles.
US08895131B2 Honeycomb structure
A honeycomb structure includes a ceramic block. A plurality of honeycomb fired bodies include first-shaped units, second-shaped units, and third-shaped units. The first-shaped units include peripheral first-shaped units. Each of the peripheral first-shaped units is disposed in such a manner as to have two sides. One side of the two sides faces one of adjacent sides of one third-shaped unit among the third-shaped units with an adhesive layer therebetween. Another side of the two sides faces one of adjacent sides of another third-shaped unit among the third-shaped units with the adhesive layer therebetween. The two sides of each of the peripheral first-shaped units or extensions of the two sides are each neither substantially parallel nor substantially perpendicular to an extension of a second side and an extension of a first side of each of the second-shaped units.
US08895128B2 Small, circular disc for the attachment of papers to a flat surface via push pins
The present invention is an improved corkboard consisting of a small, circular, moveable and removable tack landing pad which is designed to adhere to a flat surface such as a wall or computer by an adhesive strip or to a metal surface like a refrigerator or thing cabinet via a magnetic strip. This landing pad is designed to receive papers of various sizes, shapes, and stock through puncture with a standard push pin tack without damaging walls. The landing pad consists of two components—(1) an outer donut-shaped shell that is sealed at its base and is contoured inward to a narrowing angle at its tack receiving face and (2) an inner foam core. The outer shell operates to both enclose and compress the foam core. This core compression affords the foam greater tack gripping ability as well as enhanced durability by quickly regaining its original shape upon tack removal.
US08895124B2 Rubber composition based on at least one EPDM and a phase-change material, pipe incorporating same and process for preparing this composition
The present invention relates to a crosslinked rubber composition based on at least one elastomer of ethylene-propylene-diene terpolymer type (EPDM) and on at least one phase-change material (PCM), to a process for preparing this composition and to a multilayer pipe incorporating it. This composition includes at least 100 phr (phr: parts by weight per one hundred parts of elastomer(s)) of at least one phase-change material (PCM), and it is such that said at least one PCM is dispersed in the crosslinked composition and is provided with protection means that are capable of preventing its dispersion therein at a temperature above its melting point, which composition has a breaking strength of greater than 3 MPa and/or an elongation at break of greater than 100%, these properties being measured at 23° C. according to standard ASTM D 412.
US08895120B2 Plastic preform and process for the manufacturing thereof to a polychromatic container
Preform for the blow moulding of a container comprising a neck section (1) including a pouring opening (20), an adjacent wall section (2) and a bottom section (3). It consists of a primary plastic raw material in a primary area (A1, A2, A3) and at least one secondary material in at least a secondary area (B1, B2, B3) both having a mutually different coloration. Said preform is remarkable in that said bottom section (3) is composed of a multi-layer structure with primary layers composed of said primary plastic material, and additional secondary layers (6, 7, 8, 9, 10). The latter are composed of said secondary material, two surface secondary layers the one of which (6) is directed outwardly respective the preform, whereas the other one (10) is directed inwardly, and an intermediate secondary layer between them (7, 8, 9), which constitutes a core layer, which is located between two said primary layers. Said preform is in one single piece, the transition (Z1, Z2) from said primary to said secondary material being seamless and uninterrupted. The invention further relates to a manufacturing method of said preform.
US08895119B2 Thermal transfer sheet
Provided is a thermal transfer sheet capable of forming an image having excellent glossiness, and having no printing wrinkle or having a lesser possibility of generating wrinkles. A thermal transfer sheet in which a dyestuff layer or a transcriptive protective layer is formed on one surface of a substrate and a back face layer is formed on another surface of the substrate, wherein the back face layer contains (A) a resin of which weight-average molecular weight (Mw) is more than 15,000; (B) a resin of which weight-average molecular weight (Mw) is not more than 15,000; and (C) a lubricant ingredient; and wherein the (B) resin is contained at an amount range of 3% by weight to 40% by weight on the basis of the total solid content weight of the back face layer.
US08895116B2 Manufacturing method of crystalline semiconductor film and manufacturing method of semiconductor device
The crystalline semiconductor film is formed following steps that supplying a film formation gas to a second gas diffusion area from a gas introduction port provided in an upper electrode; supplying the film formation gas to a first gas diffusion area from the second gas diffusion area through holes provided in a dispersion plate between the first gas diffusion area and the second gas diffusion area; supplying the film formation gas into a treatment room from the first gas diffusion area through holes in a shower plate between the first gas diffusion area and the treatment room; generating glow discharge plasma by supplying high frequency electricity from an electrode surface of the upper electrode; generating crystal nuclei on a substrate provided over a lower electrode facing the upper electrode; and growing the crystal nuclei. A portion of the dispersion plate which faces the gas introduction port has no hole.
US08895115B2 Method for producing an ionized vapor deposition coating
A method of depositing a coating by vapor deposition. The method including ionizing a process gas, generating a metal vapor and creating a metal flow having a metal atom flow density in the range of 1E14 m−3 to 1E24 m−3. The method also includes providing a thermionic emission from a thermionic ionizing grid including thermionic filaments, wherein said ionizing filament grid is at least partially located within said region having a metal atom flow density in the range of 1E14 m−3 to 1E24 m−3, and coating a substrate with the metal vapor.
US08895108B2 Method for forming thin film using radicals generated by plasma
A method for forming a thin film using radicals generated by plasma may include generating radicals of a reactant precursor using plasma; forming a first thin film on a substrate by exposing the substrate to a mixture of the radicals of the reactant precursor and a source precursor; exposing the substrate to the source precursor; and forming a second thin film on the substrate by exposing the substrate to the mixture of the radicals of the reactant precursor and the source precursor. Since the substrate is exposed to the source precursor between the formation of the first thin film and the formation of the second thin film, the rate of deposition may be improved.
US08895107B2 Chemical vapor deposition with elevated temperature gas injection
A chemical vapor deposition reactor and method. Reactive gases, such as gases including a Group III metal source and a Group V metal source, are introduced into a rotating-disc reactor and directed downwardly onto a wafer carrier and substrates which are maintained at an elevated substrate temperature, typically above about 400° C. and normally about 700-1100° C. to deposit a compound such as a III-V semiconductor. The gases are introduced into the reactor at an inlet temperature desirably above about 75° C. and most preferably about 100°-250° C. The walls of the reactor may be at a temperature close to the inlet temperature. Use of an elevated inlet temperature allows the use of a lower rate of rotation of the wafer carrier, a higher operating pressure, lower flow rate, or some combination of these.
US08895105B2 Receptor-catalyst growth process for carbon nanotubes
A method of growing carbon nanomaterials on a substrate wherein the substrate is exposed to an oxidizing gas; a seed material is deposited on the substrate to form a receptor for a catalyst on the surface of said substrate; a catalyst is deposited on the seed material by exposing the receptor on the surface of the substrate to a vapor of the catalyst; and substrate is subjected to chemical vapor deposition in a carbon containing gas to grow carbon nanomaterial on the substrate.
US08895103B2 Shrinkable film and method for manufacturing same
Provided are a film for food packaging, capable of having excellent adhesion with a metal deposition layer and thus retaining moisture barrier property while having superior flexibility, transparency, and biodegradability, and a method for manufacturing the same.
US08895102B2 Method of treating surface of mold
A method of treating a surface of a mold that includes supplying a fullerene into an amorphous carbon layer that covers the surface of the mold and heating the amorphous carbon layer to at least 400° C. while covering a surface of the amorphous carbon layer with a covering member.
US08895101B2 Method for manufacturing cable-type secondary battery
The present invention relates to a method for manufacturing a cable-type secondary battery comprising an electrode that extends longitudinally in a parallel arrangement and that includes a current collector having a horizontal cross section of a predetermined shape and an active material layer formed on the current collector, and the electrode is formed by putting an electrode slurry including an active material, a polymer binder, and a solvent into an extruder, by extrusion-coating the electrode slurry on the current collector while continuously providing the current collector to the extruder, and by drying the current collector coated with the electrode slurry to form an active material layer.
US08895100B2 Method for manufacturing a compound film
A method for manufacturing a compound film comprising a substrate and at least one additional layer is disclosed. The method comprising the steps of depositing at least two chemical elements on the substrate and/or on the at least one additional layer using depositions sources, maintaining depositing of the at least two chemical elements while the substrate and the deposition sources are being moved relative to each other, measuring the compound film properties, particularly being compound film thickness, compound-film overall composition, and compound-film composition in one or several positions of the compound film, comparing the predefined values for the compound film properties to the measured compound film properties, and adjusting the deposition of the at least two chemical elements in case the measured compound film properties do not match the predefined compound film properties.
US08895099B2 Endoprosthesis
Endoprostheses and methods of making endoprostheses are disclosed. For example, endoprostheses are described that include an endoprosthesis body, a biodegradable metallic tie layer, and a polymer coating about the endoprosthesis body. The biodegradable tie layer and the polymer coating can have a high peel strength from the body.
US08895098B2 Coating method and coating device
A device for coating at least regions of a medical implant including a powder having at least one pharmaceutically active substance or one bone growth-promoting substance such that the powder can be transferred to the medical implant when the medical implant is contacted.
US08895096B2 Continuous oven with a cascading conveyor
A continuous oven comprising cascading conveyors. In one embodiment the oven comprises an oven floor, a ceiling, a left panel, and a right panel. The oven floor and ceiling are attached by the left and right sides defining an oven cavity. Located inside the oven cavity is at least one cascading conveyor. Also within the oven cavity is a partition which separates the oven into an upstream end and a downstream end.
US08895093B2 Method for the production of jelly confectionery
A method for making a jelly confectionery comprising preparing a liquid jelly confectionery composition comprising bulk sweetener and a hydrocolloid gelling agent, cooking the liquid jelly confectionery composition, and depositing the liquid jelly confectionery composition into a mold, wherein the viscosity of the liquid jelly confectionery composition is temporarily modified for a period of time commencing prior to deposition of the liquid jelly confectionery into a mold.
US08895091B2 Cover shell for reducing damage to food product
A cover shell and container assembly comprising the cover shell and a tray or pan is disclosed. The cover shell includes inward projecting standoffs which restrict movement of a food product in the pan or tray and reduces damage to decorative elements of the food product during distribution and/or transport.
US08895085B2 Agglomerated oil impregnated psyllium husk
There is provided agglomerated oil impregnated psyllium husk and to a method for manufacturing the agglomerated oil impregnated psyllium husk. Specifically the present invention provides compositions comprising agglomerates of psyllium husks, wherein the husks have been subjected to treatment with an oily component (e.g. vegetable oil, such as rapeseed oil) prior to a drying process, such as a fluidized bed process, wherein the husks are agglomerated with a saccharide containing aqueous suspension/solution sprayed onto the husks.
US08895084B2 Oral care composition containing extract of unoxidized Camellia
An oral composition for at least one or treating and inhibiting an oral inflammatory condition comprising: a Camellia extract including at least about 30% epigallocatechin gallate, at least about 50% total catechins, and at least about 60% total polyphenols; and a substantially water insoluble non-cationic anti-bacterial agent.
US08895083B2 Composition for the maintenance of blood sugar levels comprising cinnamon and ginseng
A composition is disclosed which comprises cinnamon or cinnamon extract such as cinnamon aqueous extract TC 112 and panax ginseng or extract from panax ginseng standardized to 1.5 to 7% ginsenosides and may comprise an artificial sweetener. The composition is embodied in the form of a pill or food product with 120 mg of cinnamon aqueous extract and 120 mg of ginseng standardized to 1.5 to 7% ginsenosides. The composition is used as a daily dosage for improvement of cognitive function, prevention or treatment of Alzheimer's disease, maintenance or lowering of blood-sugar levels, prevention of arterial disease or the improvement of cognitive function in diabetics.
US08895081B2 Formulation for treatment of dry mouth and mouth sores
Serum compositions for application to endothelial tissue are described which contain an amniotic fluid extract in combination with embryonic stem cells. Formulations containing the serum composition are also described. The serum compositions and formulations may be used to treat conditions of the mouth such as dry mouth and mouth sores.
US08895079B2 Combinations of botanical extracts for promoting cardiovascular health
A blood lipid lowering agent that functions through a same mechanism as berberine (e.g. berberine, one or more pharmacologically acceptable salts of berberine or a mixture thereof) and a blood lipid lowering agent that functions through a different mechanism than berberine (e.g. phytosterols, phytostanols, esters thereof or mixtures thereof) act synergistically to improve blood lipid profiles, for example, lowering total cholesterol, LDL-C or nonHDL-C, and triglyceride, and increasing the ratio of HDL-C to nonHDL-C. The two may be used in combination to treat or reduce the chance of contracting cardiovascular disease, hyperlipidemia, atherosclerosis, coronary heart disease, angina, cerebrovascular disease, stroke, overweight or obesity, diabetes, insulin resistance, hyperglycemia, hypertension, arrhythmia, diseases of the central nervous system, diseases of the peripheral nervous system and/or inflammation. The blood lipid lowering agent that functions through a same mechanism as berberine, with or without the blood lipid lowering agent that functions through a different mechanism than berberine, may also be used to control weight.
US08895077B2 Methods for preventing or treating infectious diseases caused by extracellular microorganisms, including antimicrobial-resistant strains thereof, using gallium compounds
The present invention relates to methods for preventing or treating infectious diseases caused by extracellular microorganisms, such as bacteria and fungi, by systemically administering to a patient a compound containing gallium. The extracellular microorganisms targeted by the present methods include methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecalis (VRE), E. coli O157:H7, fluoroquinolone-resistant Salmonella typhi, and the like. Furthermore, in the present methods, gallium compounds can be co-administered with one or more conventional antimicrobial agents to treat infectious diseases with reduced risks of creating multi-drug resistant pathogens. The methods of the present invention is also applicable to those microorganisms, such as ulcer-causing Helicobacter pylori, complete eradication of which so far has been difficult to achieve.
US08895074B2 Therapeutic application of parenteral krill oil
A method of parenterally administering a composition, the method including parenterally administering to a person a composition including krill oil in an oil-in-water emulsion. A parenterally applicable pharmaceutical composition, including an oil-in-water emulsion including a phospholipid obtained from a marine crustacean.
US08895073B2 Hydrogel implant with superficial pores
Implantable biomaterials, particularly hydrogel substrates with porous surfaces, and methods for enhancing the compatibility of biomaterials with living tissue, and for causing physical attachment between biomaterials and living tissues are provided. Also provided are implants suitable for load-bearing surfaces in hard tissue repair, replacement, or augmentation, and to methods of their use. One embodiment of the invention relates to an implantable spinal disc prosthesis.
US08895072B2 Quantum dot barcode structures and uses thereof
The present invention provides novel barcode microstructures and methods for making and using the microstructures for molecular recognition, and/or delivery of therapeutic, diagnostic, contrast, and imaging agents.
US08895069B2 Drug delivery system using hyaluronic acid-peptide conjugate micelle
The present invention relates to a drug delivery composition comprising a hyaluronic acid-peptide conjugate micelle and a production method thereof. According to the drug delivery composition and the production method of the drug-loaded, hyaluronic acid-peptide conjugate micelle of the present invention, the reaction for encapsulating can proceed in a mixed solvent of an aqueous solvent and an organic solvent. Therefore, the present invention can be applied to various types of water-insoluble active components and the biocompatible and biodegradable derivative can encapsulate a drug to provide a drug-loaded micelle, which is safe to be applied for human bodies. Moreover, the micelle has a therapeutic effect from the peptide contained therein, which can act in combination with the drug as packing therein. Therefore, the drug delivery composition and its production method can be utilized in the field of producing a sustained release formulation with an extended duration of the medicinal effect.
US08895061B2 Compositions comprising carisoprodol and methods of use thereof
The present invention provides compositions comprising carisoprodol or pharmaceutically acceptable salts, esters or derivatives thereof. In certain embodiments, the invention provides pharmaceutical compositions comprising the skeletal muscle relaxant carisoprodol and one or more additional active agents, such as one or more nonsteroidal antiinflammatory drugs (NSAIDs). The invention further provides methods of use of such compositions in preventing, alleviating and/or treating musculoskeletal pain, muscle spasms, or other non-malignant painful conditions including methods in which the circulating levels of the active pharmaceutical form of carisoprodol are controlled by use of extended- or controlled-release formulations or by strict control of dosage regimen, so as to reduce the level of somnolence observed with other muscle relaxant compositions.
US08895059B2 Reduction of cross-linking gelatin in gelatin capsules
The invention relates to compositions and methods for reducing cross-linking in the gelatin shell of gelatin capsules by incorporation of free amino acid into the capsule shell and by inclusion of an ester of carboxylic acid either into the capsule filling, and/or into the capsule shell and/or into the lubrication agent, or in combinations thereof. Described are soft gelatin capsules characterized by improved stability as compared with gelatin capsules that do not contain amino acid in the shell and carboxylic acid ester in the filling, shell or in the lubrication agent, or in combinations thereof.
US08895058B2 Low dose topiramate/phentermine composition and methods of use thereof
A method for effecting weight loss by administering a combination of topiramate and phentermine is provided. The phentermine is generally administered in immediate release form, in a daily dose in the range of 2 mg to 8 mg, in combination with a daily dose of topiramate selected to prevent the loss of effectiveness of phentermine alone. Methods for treating obesity, conditions associated with obesity, and other indications are also provided, as are compositions and dosage forms containing low doses of phentermine and topiramate, e.g., 3.75 mg phentermine and 23 mg topiramate.
US08895057B2 Escalating dosing regimen for effecting weight loss and treating obesity
The present invention is drawn to novel topiramate compositions as well as methods for effecting weight loss, e.g., in the treatment of obesity and related conditions, including conditions associated with and/or caused by obesity per se. The present invention features an escalating dosing regimen adapted for the administration of topiramate and optionally a sympathomimetic agent such as phentermine or bupropion, in the treatment of obesity and related conditions.
US08895053B2 Testosterone formulations
The subject invention provides improved testosterone gel formulations.
US08895050B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof
The present invention relates to the discovery that certain non-naturally occurring, non-peptide amide compounds and amide derivatives, such as oxalamides, ureas, and acrylamides, are useful flavor or taste modifiers, such as a flavoring or flavoring agents and flavor or taste enhancer, more particularly, savory (the “umami” taste of monosodium glutamate) or sweet taste modifiers, —savory or sweet flavoring agents and savory or sweet flavor enhancers, for food, beverages, and other comestible or orally administered medicinal products or compositions.
US08895049B2 Extended release biodegradable ocular implants
Biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The implants provide an extended release of an active agent at a therapeutically effective amount for a period of time between 50 days and one year, or longer.
US08895048B2 Templated islet cells and small islet cell clusters for diabetes treatment
Substrates and devices for culturing cells are disclosed, along with methods of using the same. The substrates and devices include top surfaces with one or more divots disposed therein. Each divot is defined by an opening in the top surface, a rounded bottom surface spaced from the opening, and an interior side-wall surface extending between the rounded bottom surface and the opening. The top surface of the substrates and devices are optionally walled to form wells containing one or more divots. The substrates and devices may be used for reaggregating cells, for example, to form small islet cell clusters and for high throughput testing methodologies.
US08895046B2 Orthopaedic implant for supporting tissue growth and methods of forming the implant and tissue
Adult autologous stem cells cultured on a porous, three-dimensional tissue scaffold-implant for bone regeneration by the use of a hyaluronan and/or dexamethasone to accelerate bone healing alone or in combination with recombinant growth factors or transfected osteogenic genes. The scaffold-implant may be machined into a custom-shaped three-dimensional cell culture system for support of cell growth, reservoir for peptides, recombinant growth factors, cytokines and antineoplastic drugs in the presence of a hyaluronan and/or dexamethasone alone or in combination with growth factors or transfected osteogenic genes, to be assembled ex vivo in a tissue incubator for implantation into bone tissue.
US08895042B2 Non-toxic and environmentally compatible photo-protective preparations
The present invention relates generally to methods and compositions for prophylaxis and treatment of skin conditions. Topical compositions which protect the skin from UV radiation damage and treat UV radiation damage done to the skin are provided according to embodiments of the present invention which include at least one cyanin derived from a plant and at least one additional agent selected from the group consisting of: a UV radiation reflector, a UV screening agent, niacinamide, and a combination of two or more thereof.
US08895028B2 Methods and compositions for dengue virus 3 (DV3) infectious clone
The present invention provides a nucleic acid molecule comprising a nucleotide sequence encoding an infectious RNA molecule encoding a live viral strain of a dengue 3 virus (DV3), wherein said nucleotide sequence is the nucleotide sequence of SEQ ID NO:1 or a nucleotide sequence having at least 99% identity with the nucleotide sequence of SEQ ID NO.1.
US08895027B2 Recombinant feline leukemia virus vaccine containing optimized feline leukemia virus envelope gene
The present invention provides vectors that contain and express in vivo or in vitro FeLV antigens that elicit an immune response in animal or human against FeLV, compositions comprising said vectors and/or FeLV polypeptides, methods of vaccination against FeLV, and kits for use with such methods and compositions.
US08895026B2 Attenuated pestivirus
The present invention relates to recombinant attenuated pestiviruses, in particular to recombinant attenuated CSFV, BVDV, or BDV, wherein said recombinant attenuated pestivirus does not produce a dimeric Erns glycoprotein. The present invention also relates to immunogenic compositions comprising such a pestivirus as well to a method of attenuating a pestivirus comprising the step of modifying the Erns glycoprotein by a deletion, insertion or substitution wherein such modification results in a non dimeric Erns glycoprotein.
US08895021B2 Sequences of brachyspira, immunogenic compositions, methods for preparation and use thereof
Novel polynucleotide and amino acids of Brachyspira hyodysenteriae are described. These sequences are useful for diagnosis of B. hyodysenteriae disease in animals and as a therapeutic treatment or prophylactic treatment of B. hyodysenteriae disease in animals. These sequences may also be useful for diagnostic and therapeutic and/or prophylactic treatment of diseases in animals caused by other Brachyspira species.
US08895018B2 Recombinant T-cell receptor ligand for the treatment of cognitive and neuropsychiatric impairment induced by substance addiction
Methods are provided for the treatment of subjects with cognitive or neuropsychiatric impairment induced by substance addiction and for increasing cognitive function in a subject with substance addiction. In some embodiments, the methods include administering to the subject a therapeutically effective amount of a major histocompatibility complex (MHC) molecule including covalently linked first, second, and third domains; wherein the first domain is an MHC class II β1 domain and the second domain is an MHC class II α1 domain; or wherein the first domain is an MHC class I α1 domain and the second domain is an MHC class I α2 domain; and wherein the third domain is covalently linked to the first domain and comprises an antigen of the central or peripheral nervous system.
US08895011B2 Insulin-resistance-improving drug
Provided are a means for the prevention and treatment of obesity and/or insulin resistance and, particularly, pharmaceutical drugs for the treatment of obesity and/or insulin resistance under the influence of Follistatin-like 3 (FSTL3). Specifically, provided is an insulin resistance improving drug comprising an FSTL3 inhibitor as an active ingredient, particularly, the insulin resistance improving drug, wherein the FSTL3 inhibitor is one of (A) a substance specifically binding to FSTL3 to inhibit or suppress a function of FSTL3, (B) an inhibitor for expression of FSTL3, and (C) a competitor of FSTL3.
US08895006B2 Ricin ribosome binding protein compositions and methods of use thereof
Compositions and methods for treatment of toxin poisoning are disclosed.
US08895004B2 Method for the treatment of amyloidoses
The present invention relates to a method for the treatment of an amyloidosis such as Alzheimer's disease in a subject in need thereof, characterized in that it comprises administering an inhibitor of the interaction between Aβ globulomer and the P/Q type voltage-gated presynaptic calcium channel to said subject.
US08895002B2 Hemojuvelin fusion proteins and uses thereof
The present invention provides a hemojuvelin (HJV) fusion protein (e.g., a human HJV.Fc) protein, polynucleotides and vectors encoding such proteins, and methods for making such proteins. Also provided are methods for treating iron-related disorders which include administration of a HJV fusion protein to a patient in need thereof.
US08894997B2 Monoclonal antibodies to influenza H1N1 virus uses thereof
The present invention is directed to particular monoclonal antibodies and fragments thereof that find use in the detection, prevention and treatment of influenza virus infections. In particular, these antibodies may neutralize or limit the replication of H1N1 influenza virus. Also disclosed are improved methods for producing such monoclonal antibodies.
US08894996B2 Immunoadjuvant composition and use thereof
Disclosed is a composition comprising, as an active ingredient, at least one selected from the group consisting of a Zc3h12a gene inhibitor and a Zc3h12a protein inhibitor. This composition can be used as an immunoadjuvant.
US08894986B2 Wound healing compositions including cyanoacrylate monomers and phenytoin
A monomeric adhesive composition includes a stabilized polymerizable monomer, such as a 1,1-disubstituted monomer, including a cyanoacrylate, and a wound healing agent, wherein the wound healing agent is 5,5-disubstitutedhydantoin, including phenytoin; and a method for making said composition.
US08894976B2 Fluorescent membrane intercalating probes and methods for their use
The invention relates to a family of dyes which fluoresce in the UV-VIS, far red and near infrared wavelengths of the spectrum and possess asymmetric lipophilic alkyl chains. The dyes of the invention are soluble in commercially available membrane staining dyes, are useful as probes for rapidly staining lipophilic structures such as membranes in cells or isolated from cells, and are well-retained therein. Methods of utilizing the dyes to detect stained cells both in vivo and in vitro are also disclosed.
US08894973B2 Method and system for differential diagnosis of chronic schizophrenia and chronic alcoholism
The invention is a method for the differential diagnosis of chronic schizophrenia or chronic alcoholism, by imaging the brain of a subject to detect any or all of the markers phosphocreatine (PCr), N-acetyl aspartate divided by the total creatine signal (NA/Crt), and synaptic phosphodiester (sPDE), and determining any increase or decrease in the presence of such markers compared to normal levels in specified anatomic areas of the brain. The output of such a method, resulting from such imaging, is presented to be viewed by a diagnostician in order to support the differential diagnosis based on the data output.
US08894971B2 Iodine radiolabelling method
The present invention provides a novel method of labelling biological targeting molecules (BTMs) of interest with radioiodine. Also provided are novel radioiodinated BTMs prepared using the method, as well as radiopharmaceutical compositions comprising such radioiodinated BTMs. The invention also provides radioiodinated intermediates useful in the method, as well as in vivo imaging methods using the radioiodinated BTMs.
US08894969B2 Method and device for radiotherapy
A radiotherapy method, comprising positioning a predetermined amount of a radionuclide selected from the group consisting of Radium-223, Radium-224, Radon-219 and Radon-220, in proximity to and/or within a tumor of a subject, for a predetermined time period. The predetermined amount and the predetermined time period are selected sufficient for the radionuclide to administering a predetermined therapeutic dose of decay chain nuclei and alpha particles into the tumor.
US08894965B2 Energy recovery in manufacture of sulfuric acid
This invention relates to the recovery of energy in the manufacture of sulfuric acid, and more particularly to enhanced recovery of energy from the absorption of wet SO3 in sulfuric acid. The invention is further directed to control of mist formation during SO3 absorption, and of the sulfuric acid mist content of the gas stream leaving the SO3 absorption step in a process wherein SO3 absorption energy is recovered from absorption acid in useful form.
US08894964B2 Crystalline carbonaceous material with controlled interlayer spacing and method of preparing same
A crystalline carbon material with controlled interlayer spacing and a method of manufacturing the crystalline carbon material are disclosed. The crystalline carbon material has peaks of a (002) plane at 2θ=23°±5.0° and 2θ=26.5°±1.0° when X-ray diffraction is measured using a CuKα ray. The peak height at 2θ=23°±5.0° is higher than the one at 2θ=26.5°±1.0°.
US08894959B2 Silicon Production method
There is provided a silicon production method which comprises producing semiconductor grade silicon while producing solar grade silicon by converting a portion of trichlorosilane into silicon for solar cells.There is also provided an industrially advantageous method that removes contaminants from a chlorosilane circulating system which produces trichlorosilane in producing silicon from trichlorosilane by a vapor deposition method.
US08894957B2 Method of producing nanophosphor particles
Provided is a method of producing spherical nanophosphor particles having a uniform size distribution. When nanophosphor obtained using the method is used in a flat panel display, the flat panel display has higher screen brightness and a higher resolution.
US08894953B2 Carbon dioxide recovery system and method of exhaust gas
Disclosed is a method for recovering carbon dioxide from exhaust gas, more particularly, a method for recovering carbon dioxide from exhaust gas for saving the cost for recovery of carbon dioxide by decreasing energy required for recycling a carbon dioxide absorbent solution. In particular, a circulating solvent, whose heat of vaporization and/or sensible heat is lower than that of a solvent of an absorbent solution introduced to a recycling tower, is supplied to the lower portion of the recycling tower and mixed with the heated absorbent solution. As a result, the pressure inside the recycling tower is maintained so that carbon dioxide released from the absorbent solution is discharged to a storage tank/drum.
US08894950B2 Sealing means for test cassette
Disclosed is a test cassette comprising a continuous length of test carrier tape (22) in a supply chamber (12), the supply chamber (12) having an opening (52) sized so as to allow the test carrier tape (22) to pass through into a test zone (32) into an uptake chamber (14) where the test carrier tape (22) coils itself onto an uptake mandrel (26), the supply chamber (12) being sealed from the environment whereby the opening (52) of the supply chamber (12) allowing the exit of the test carrier tape (22) has a spacer (42) disposed either side of it, filling the remaining width of the opening (52) of the housing (16), a cover plate (34) being biased by a spring (38) to cover the spacer (42) and tape (22), thus covering the opening (52) and sealing the cassette (10).
US08894947B2 Systems and methods for thermal actuation of microfluidic devices
A microfluidic processing device includes a substrate defining a microfluidic network. The substrate is in thermal communication with a plurality of N independently controllable components and a plurality of input output contacts for connecting the substrate to an external controller. Each component has at least two terminals. Each terminal is in electrical communication with at least one contact. The number of contacts required to independently control the N components is substantially less than the total number of terminals. Upon actuation, the components typically heat a portion of the microfluidic network and/or sense a temperature thereof.
US08894946B2 Sample preparation, processing and analysis systems
This disclosure provides an integrated and automated sample-to-answer system that, starting from a sample comprising biological material, generates a genetic profile in less than two hours. In certain embodiments, the biological material is DNA and the genetic profile involves determining alleles at one or a plurality of loci (e.g., genetic loci) of a subject, for example, an STR (short tandem repeat) profile, for example as used in the CODIS system. The system can perform several operations, including (a) extraction and isolation of nucleic acid; (b) amplification of nucleotide sequences at selected loci (e.g., genetic loci); and (c) detection and analysis of amplification product. These operations can be carried out in a system that comprises several integrated modules, including an analyte preparation module; a detection and analysis module and a control module.
US08894941B2 Air pollution control system and method
SOx removal equipment for reducing sulfur oxides from flue gas from a boiler, a cooler provided on a downstream side of the SOx removal equipment, for reducing the sulfur oxides that remain in the flue gas and decrease a gas temperature, CO2 recovery equipment including an absorber for bringing CO2 in the flue gas into contact with a CO2 absorption liquid to be reduced, and a regenerator for causing the CO2 absorption liquid to emit CO2 to recover CO2 and regenerate the CO2 absorption liquid, a heat exchanger which is provided on an inlet passage side of the electric dust collector, for decreasing a temperature of the flue gas are included, and a mist generation material in the flue gas is converted from a gas state to a mist state to cause particulates in the flue gas to arrest and reduce the mist generation material in the mist state.
US08894940B2 Process and apparatus for distributing hydrocarbon feed and catalyst
A process and apparatus for fluid catalytic cracking feeds catalyst to a chamber of a riser. The catalyst exits the chamber and passes through a plenum and into a reaction zone through a plurality of tubes which distribute the catalyst uniformly over a cross section of the reaction zone of the riser. A hydrocarbon feed is fed to the plenum. The hydrocarbon feed passes from the plenum into the reaction zone through a plate comprising a multiplicity of openings which distribute the hydrocarbon feed uniformly over a cross section of the reaction zone of the riser. The feed is contacted with the catalyst in a reaction zone of the riser.
US08894939B2 Three phase reactor
A reactor for carrying out a chemical reaction in a three phase slurry system providing a horizontal reaction vessel with a cross sectional area which is dependent on the vessel length, vessel diameter, and axial position. The vessel has a gas inlet at or near the bottom of the reaction vessel and a gas distributor. The gas product exits the vessel by conduit means at or near the top of the reaction vessel. The vessel includes a plurality of horizontal cooling coils to provide a cooling medium to the slurry. In the reaction vessel, the synthesis gas has an average linear velocity which is a function of the vessel cross sectional area.
US08894937B2 Method for using a deodorizing system
A method of producing a deodorizing or odor neutralizing fog includes a tank with an input port and an exit port, and a fogging portion located within the tank. A deodorizing or odor neutralizing liquid is added to the tank upon which the fogging portion is configured to float. Compressed air is input through said input port and is expelled on the deodorizing or odor neutralizing liquid through at least one nozzle located on the fogging portion, thereby vaporizing the deodorizing or odor neutralizing liquid. The vapor combines with the compressed air within the tank to form the deodorizing or odor neutralizing fog.
US08894935B2 Monitoring system for selective catalyst reduction system
A monitoring system for a selective catalyst reduction system according to the present invention includes a selective catalyst reduction system that reacts with ammonia and reduces NOx, a first NOx sensor that is disposed upstream of the selective catalyst reduction system and measures the amount of the NOx that flows into the selective catalyst reduction system, a second NOx sensor that is disposed downstream of the selective catalyst reduction system and measures the amount of the NOx that is reduced, an injector that is disposed between the first NOx sensor and the selective catalyst reduction system and injects a urea solution, and a control portion that calculates reduction efficiency based on signals that are detected from the first NOx sensor and the second NOx sensor, determines the necessary amount of the ammonia according to the reduction efficiency, and controls the injection amount of the urea solution through the injector. The first and second NOx sensors are mean value sensors having a permissible deviation of ±6.7%.
US08894934B2 Sensing devices and techniques using 3-D arrays based on surface plasmon excitations
Techniques, apparatus, material and systems are described for implementing a three-dimensional composite mushroom-like metallodielectric nanostructure. In one aspect, a surface plasmon based sensing device includes a substrate and a layer of an anti-reflective coating over the substrate. The surface Plasmon based sensing device includes a dielectric material on the anti-reflective coating shaped to form a 2-dimensional array of nanoholes spaced from one another. Also, the surface Plasmon based sensing device includes a layer of a metallic film formed on the 2-dimensional array of nanoholes to include openings over the nanoholes, respectively, wherein the sensing device is structured to support both propagating surface plasmon polariton (SPP) waves and localized surface plasmon resonant (LSPR) modes.
US08894932B2 Reagent preparing device and specimen processing system
A reagent preparing device capable of supplying a predetermined reagent, which includes a first liquid and a second liquid different from the first liquid, to a measurement section for measuring a specimen using the reagent, comprising: a reagent preparing section for preparing the predetermined reagent; a characteristic measurement device for measuring characteristic of the reagent prepared by the reagent preparing section; and a controller configured for performing operations comprising, controlling the supply of reagent prepared by the reagent preparing section to the measurement section according to the measurement result by the characteristic measurement device, and calibrating the characteristic measurement device based on a known characteristic value of a standard liquid having the known characteristic value and a measurement result obtained by measuring the characteristic of the standard liquid by the characteristic measurement device, is disclosed. A specimen processing system is also disclosed.
US08894928B2 Junction, device and process for transporting sample racks
A junction for transporting sample racks in an analytical system having one or more work cells for processing samples and a method thereof are disclosed. In one embodiment, the junction may include multiple main transport lines, a turntable and one or more bypass transport lines. The multiple main transport lines can transport first sample racks and second sample racks having different sizes. The rotatable transport line can alternately connect to one or more of the main transport lines. Each of the one or more bypass transport lines can interconnect two of the main transport lines and bypass the turntable. Each of the bypass transport lines can be curved such that transport of the second sample racks through each of the bypass transport lines is enabled and transport of the first sample racks through each of the bypass transport lines is disabled.
US08894926B2 Sterilization apparatus and sterilization method
It is to provide a mechanism where a sterilization process using a concentrated sterilizing agent and a sterilization process using a sterilizing agent that has not been concentrated can be switched without changing the sterilization process.In the case where the concentrated mode is received by receiving means the transfer of the sterilizing agent to the concentration chamber is controlled according to a first timing, and in the case where the non-concentrated mode is received by the receiving means, the transfer of the sterilizing agent to the concentration chamber is controlled according to a second timing, wherein the first timing is different from the second timing.
US08894922B2 Fireproof ceramic impact pad
The invention relates to a fireproof ceramic impact absorber.
US08894920B2 Methods and apparatus for casting ceramic sheets
A method for making a thin, free-standing ceramic sheet may include drawing a carrier film proximate a casting head and across a casting bed of a tape caster at a rate from about 2 cm/min to about 500 cm/min. Depositing a thin film of ceramic slip less than about 150 μm on the carrier film with the casting head. The ceramic slip may comprises a ceramic powder with an ultimate crystallite size of less than about 10 μm dispersed in a fluid vehicle such that the ceramic slip has a ceramic solids fraction of greater than about 20% by volume. The deposited ceramic slip may be dried on the carrier film thereby forming a green ceramic sheet on the carrier film. After the green ceramic sheet is dried, the green ceramic sheet may be sintered.
US08894919B1 Method for incorporation of insulators and bulk absorbers in high temperature sandwich structures after fabrication
A method for adding insulation or bulk absorbers into high temperature sandwich structures following fabrication is presented. A slurry of ceramic fibers and/or particles, opacified particles, fugitive fibers, organic binders and inorganic binders is prepared as an aqueous solution. The slurry is cast within a prepared sandwich structure, dried, and heated to form a low density ceramic core material to provide insulation or noise absorption. Following incorporation of the ceramic material, aerogels or phase change materials may also be added to provide additional thermal management benefits.
US08894918B2 Methods for producing high-performance silicon carbide fibers, architectural preforms, and high-temperature composite structures
Methods are disclosed for producing architectural preforms and high-temperature composite structures containing high-strength ceramic fibers with reduced preforming stresses within each fiber, with an in-situ grown coating on each fiber surface, with reduced boron within the bulk of each fiber, and with improved tensile creep and rupture resistance properties tier each fiber. The methods include the steps of preparing an original sample of a preform formed from a pre-selected high-strength silicon carbide ceramic fiber type, placing the original sample in a processing furnace under a pre-selected preforming stress state and thermally treating the sample in the processing furnace at a pre-selected processing temperature and hold time in a processing gas having a pre-selected composition, pressure, and flow rate. For the high-temperature composite structures, the method includes additional steps of depositing a thin interphase coating on the surface of each fiber and forming a ceramic or carbon-based matrix within the sample.
US08894914B2 Method for the manufacture of a cermet-containing bushing
One aspect relates to a method for the manufacture of an electrical bushing for use in a housing of an active implantable medical device. The electrical bushing includes an electrically insulating base body and an electrical conducting element. The conducting element is set-up to establish, through the base body, an electrically conducting connection between an internal space of the housing and an external space. The conducting element is hermetically sealed with respect to the base body. The conducting element includes at least one cermet.One aspect provides the method including forming a base body green compact having a through-opening that extends through the base body green compact from a ceramic slurry, generating at least one conducting element green compact from a cermet slurry, producing a bushing blank by combining the conducting element green compact and the base body green compact, and separating the bushing blank into two electrical bushings.
US08894905B2 Heat treat configuration for porous carbon-carbon composites
A method of heat treating a substrate for a fuel cell includes stacking substrates to form a group. A dimension is determined for a plate corresponding to a resulting mass that is less than a predetermined mass. The plate is arranged above the group to apply a weight of the plate to the group. The resulting masses for spacer plates and intermediate lifting plates, for example, are minimized to reduce the pressure differential between the bottom and top substrates in the heat treat assembly. In another disclosed method, a dimension for a plate, such as a top plate, is determined that corresponds to a resulting mass that is greater than a predetermined mass. The plate is arranged above the group to apply a weight of the plate to the group. The top plate resulting mass is selected to minimize a variation in the average pressure of the substrates throughout the heat treat assembly.
US08894901B2 Method of making a sheet of building material
A method of making a sheet of building material, useful for roofing or siding applications, and the sheet material made by such method. A mixture of a thermoplastic resin and mineral filler is prepared, the resin comprising about 10% to 40% by weight of the mixture and the filler comprising about 60% to 90% by weight. The mixture is mixed at a temperature above the melting point of the resin and is formed into a sheet at such temperature. The sheet is allowed to cool until the surface is at a temperature below the midpoint of the melting range of the thermoplastic resin, e.g. in the range of 210 to 220 degrees F. (99 to 104 degrees C.), for polyethylene, at which point it is strained by passing it through calendering rollers. The sheet material made by this process, having a high concentration of mineral filler, is fire resistant, durable, ductile, of moderate weight and resistant to weathering. It can be produced using relatively inexpensive manufacturing equipment. The sheet material can incorporate a high proportion of recycled resin, such as recycled high density polyethylene.
US08894900B2 Stent with flexible sections in high strain regions
A stent for treating a bodily lumen with a flexible section in a high strain region is disclosed. A flexible section may be selectively positioned to reduce an amount of strain in the high strain region when subjected to the applied stress during use to inhibit or prevent fracturing in the high strain region.
US08894899B2 Method of producing friction material
Provided is a method of producing a friction material that can prevent occurrence of dust generation and segregation at the time of mixing raw materials of the friction material and that is resistant to deterioration of the friction material even when a phenol resin is employed as a binder and that also allows the production process to be effected safely and speedily and at a low cost. The method includes a mixing step (A) for stirring the raw materials for the friction material containing a high-ortho phenol resin, slaked lime and 3-10 wt. % of water and a forming step (B) for forming a mixture powder obtained from the mixing step (A) to a desired shape at room temperature.
US08894898B2 Pressed, waxy, solid cleaning compositions and methods of making them
The present invention relates to a method of making a solid cleaning composition. The method can include pressing and/or vibrating flowable waxy particles of a waxy cleaning composition. For a waxy cleaning composition, pressing and/or vibrating flowable waxy particles determines the shape and density of the solid but is not required for forming a solid. The method can employ a concrete block machine for pressing and/or vibrating. The present invention also relates to a solid cleaning composition made by the method and to solid cleaning compositions including particles bound together by a binding agent.
US08894892B2 Mold and manufacturing method therefor
Providing a mold and a manufacturing method therefor wherein protrusions are easy to be pressed into a resin base material and the protrusions are easy to be pulled out from the resin base material. The present invention provides a mold comprising a stamping surface (1a) formed depending on a via pattern and a protruding portion (21, 22) formed in convex shape from the stamping surface (1a), wherein the protruding portion has a base portion (111, 121) merging into a main surface of the stamping surface (1a) to have a curvature and a slope portion (113, 123) progressively decreasing in outer diameter thereof from the base portion (111, 121) to a top portion (112, 122) of the protruding portion (21, 22).
US08894890B2 Titanium dioxide nano particle modified by surface stabilizer, titanium dioxide nano ink comprising the same, solar cell employing the same, and producing method of the same
Disclosed are a titanium dioxide nano ink having such a strong dispersibility as to be applicable by inkjet printing and having adequate viscosity without requiring printing several times, and a titanium dioxide nano particle modified by a surface stabilizer included therein. Inkjet printing of the titanium dioxide nano ink enables printing of a minute electrode. In addition, efficiency of a solar cell may be maximized since occurrence of pattern cracking is minimized.
US08894887B2 Organic photovoltaic devices comprising fullerenes and derivatives thereof
Photovoltaic cells comprising an active layer comprising, as p-type material, conjugated polymers such as polythiophene and regioregular polythiophene, and as n-type material at least one fullerene derivative. The fullerene derivative can be C60, C70, or C84. The fullerene also can be functionalized with indene groups. Improved efficiency can be achieved.
US08894886B1 Reductive-expansion synthesis of graphene
Exemplary embodiments provide materials and methods for forming graphene-based exfoliated products with low oxygen contents by a reductive-expansion reaction from a physical mixture containing graphite-based precursor(s) and a chemical agent. Exemplary embodiments also provide materials and methods for forming graphene-based exfoliated products with controllable amounts of nitrogen and/or other impurities incorporated in the material structure as a result of a reductive-expansion reaction from a physical mixture containing graphite-based precursor(s) and a chemical agent.
US08894881B2 1,8-naphthalimide derivatives as scintillation agents, in particular for discriminating between fast neutrons and gamma rays
The invention relates to the use of 1,8-naphthalimide derivatives and of their salts as scintillation agents and more specifically as agents for discriminating between fast neutrons and gamma rays.It also relates to liquid scintillators comprising these scintillation agents in solution in a solvent and to novel 1,8-naphthalimide derivates of use as scintillation agents, in particular for discriminating between fast neutrons and gamma rays.Applications: all the fields of use of scintillators and in particular industry, geophysics, fundamental physics, in particular nuclear physics, the safety of goods and people, protection from radiation of workers in the industrial, nuclear and medical sectors, medical imaging, and the like.
US08894880B2 Wholly aromatic liquid crystal polyester resin compound having improved insulation properties
Provided is a wholly aromatic liquid crystalline polyester resin compound having excellent electrical insulating properties, heat resistance, and mechanical strength due to the inclusion of an inorganic filler having low electrical conductivity, high heat resistance, and high mechanical strength.
US08894877B2 Method, apparatus and composition for wet etching
A liquid composition for wet etching has improved selectivity for polysilicon over silicon dioxide, even when the polysilicon is heavily doped and/or the silicon dioxide is a low temperature oxide. The composition comprises 0.05-0.4 percent by weight hydrofluoric acid, 15-40 percent by weight nitric acid, 55-85 percent by weight sulfuric acid and 2-20 percent by weight water. A method and apparatus for wet etching using the composition are also disclosed.
US08894875B2 Lubricant for compression refrigerating machine and refrigerating apparatus using the same
The present invention provides a lubricating oil for a compression type refrigerator including a polyvinyl ether-based compound containing an alkylene glycol or polyoxyalkylene glycol unit and a vinyl ether unit in a molecule and having a molecular weight in a range of 300 to 3,000, an epoxy compound having 8 or more carbon atoms The lubricating oil for a compression type refrigerator of the present invention has high miscibility and high viscosity index, and is excellent in stability, and does not have an unpleasant odor under carbon dioxide atmosphere.
US08894874B2 Heat transfer compositions
The invention provides a heat transfer composition comprising (i) from about 45 to about 75% by weight 2,3,3,3-tetrafluoropropene (R-1234yf); and (ii) from about 25 to about 55% by weight 1,1,1,2-tetrafluoroethane (R-134a). A heat transfer composition comprising, optionally consisting essentially of, (i) from about 20 to about 90% by weight R-1234yf; (ii) from about 10 to about 60% by weight R-134a; and (iii) from about 1 to about 20% by weight R-32 is also provided.
US08894871B2 Lithography method using tilted evaporation
The present invention relates to a lithography method using tilted evaporation, and includes: (1) coating a resist on top of a substrate; (2) patterning the resist using a lithography process; (3) tilt-evaporating a first thin film material on an upper layer of the patterned resist to form a modified pattern mask; (4) evaporating a second thin film material on the top of the substrate with the modified pattern mask; and (5) removing the resist coated on the top of the substrate.
US08894870B2 Multi-step method and apparatus for etching compounds containing a metal
A system and method for etching a material, including a compound having a formulation of XYZ, wherein X and Y are one or more metals and Z is selected from one or more Group 13-16 elements, such as carbon, nitrogen, boron, silicon, sulfur, selenium, and tellurium, are disclosed. The method includes a first etch process to form one or more first volatile compounds and a metal-depleted layer and a second etch process to remove at least a portion of the metal-depleted layer.
US08894868B2 Substrate containing aperture and methods of forming the same
A method of forming an aperture (e.g., a through via, a blind via, a trench, an alignment feature, etc.) within a substrate includes irradiating a substrate with a laser beam to form a laser-machined feature having a sidewall. The laser-machined feature is then processed to change at least one characteristic (e.g., the sidewall surface roughness, diameter, taper, aspect ratio, cross-sectional profile, etc.) of the laser-machined feature. The laser-machined feature can be processed to form the aperture by performing an isotropic wet-etch process employing an etchant solution containing HNO3, HF and, optionally acetic acid.
US08894867B2 Method for producing and structuring a zinc oxide layer and zinc oxide layer
Disclosed is a method for producing ZnO contact layers for solar cells. The layers are etched using hydrofluoric acid so as to generate a texture.
US08894860B2 Gallium-68 radioisotope generator and generating method thereof
A Gallium-68 (Ga-68) radioisotope generator includes a generating column and a citrate eluent. The generating column is at least partially filled with an ion-exchange resin with glucamine groups to absorb germanium-68 (Ge-68) and Ga-68 radioisotopes. The citrate eluent is added into the generating column to desorb the Ga-68 radioisotope and form an eluent containing the Ga-68 radioisotope in the form of Ga-68 citrate. A method for generating Ga-68 radioisotope is also disclosed.
US08894859B2 Asymmetric membranes for use in nanofiltration
Improved integrally skinned asymmetric membranes for organic solvent nanofiltration, and their methods of preparation and use are disclosed. Membranes are formed from polyimides by phase inversion and are then crosslinked by addition of amine crosslinking agents that react with the imide groups of the polyimide, creating amide bonds. These stabilize the membranes and allow solvent nanofiltration to be maintained even in the solvents from which the membranes were formed by phase inversion.
US08894853B2 Easy-fit filter device for a water purifier
A filter device for a water purifier including a filter unit having a flange having an inlet, an outlet, an optional discharge port, opposite engaging protrusions, and opposite engaging recesses; a connecting member fitted into the flange so as to be connected with the inlet, the outlet, and optional discharge port and having inner communicating passages so as to be connected with respective connecting holes, a cap member fitted around the flange to cover the connecting member and having on an outer circumference connecting ports communicating with the respective connecting holes, the cap member having opposite engaging holes corresponding to the engaging protrusions and opposite engaging grooves corresponding to the engaging recesses, and a fixing member engaging on an inner end with the engaging recess through the engaging groove.
US08894852B2 Machine tool coolant reconditioning system
A system for producing and supplying a coolant to a filtration sub-system, and for reconditioning and recombining a return flow of used coolant. A main reservoir is in two way communication with the filtration sub-system via a clean coolant outlet and a dirty coolant return. An inlet feeds an untreated water supply to a de-ionization canister. A mixing valve in communication with the inlet recombines a remaining untreated portion of the water supply with the de-ionized portion. A mixing pump intermixes the water supply with a chemical concentrate to produce a coolant delivered to a main reservoir. A volume of coolant is drawn through an outlet from the reservoir and communicates the coolant to a particle filter, a chiller, and prior to outputting to the filtration sub-systems. The used return coolant is filtered and reintroduced to the main reservoir.
US08894847B2 Adapting multipurpose liquid filter
A liquid reclamation assembly is provided for processing a lubricant or other liquid. The assembly includes a housing interior for receiving a filter subassembly. A manifold is in fluid communication with a discharge region of the filter subassembly, the manifold comprising a primary manifold passage for passage of source fluid and a series of draw ports. The cross sectional area of the primary manifold passage is greater than the total cross sectional area of the series of draw ports to create a venturi effect to draw fluid through the assembly. The filter subassembly includes a series of target filtration segment, each segment being designed for a specific reclamation process. An entry manifold governs and distributes the fluid to each of the target filtration segments. Results of an analysis of the fluid can be used to determine which target filtration segments are desired for processing the fluid. Valves within the entry manifold can direct the flow accordingly.
US08894845B2 Alkali metal hydroprocessing of heavy oils with enhanced removal of coke products
Hydrocarbon feedstreams are desulfurized using an alkali metal reagent, optionally in the presence of hydrogen. Improved control over reaction conditions can be achieved in part by controlling the particle size of the alkali metal salt and by using multiple desulfurization reactors. The processes herein allow a simple and effective method for removing the majority of coke formed in the alkali metal reagent reactions with the hydrocarbon feedstreams. This makes it cost effective to run such processes at higher severities (which result in higher coke production) thereby resulting in increased amounts of valuable converted hydrocarbon product yields. The process improvements herein may also be used to increase total throughput through a unit due to the ability to effectively manage higher coke content in the reaction products.
US08894840B2 Process for recovering products from two reactors
A process is disclosed for catalytically converting two feed streams. The feed to a first catalytic reactor may be contacted with product from a second catalytic reactor to effect heat exchange between the two streams and to transfer catalyst from the product stream to the feed stream. The feed to the second catalytic reactor may be a portion of the product from the first catalytic reactor.
US08894839B2 Process, system, and apparatus for a hydrocracking zone
One exemplary embodiment can be a process for a hydrocarbon feed. The process can include passing a stream through a separation zone forming a void for separating one or more gases from one or more liquids and at least partially containing a catalyst. The catalyst may include at least one group VIII noble metal. Typically, the separation zone is downstream of a hydrocracking zone for reducing the operating pressure in the hydrocracking zone.
US08894828B2 FIB process for selective and clean etching of copper
Etch assisting agents for focused ion beam (FIB) etching of copper for circuit editing of integrated circuits both prevent loss of adjacent dielectric due to sputtering by the ion beam, and render sputtered re-deposited copper on adjacent surfaces non-conductive to avoid electrical short circuits. The agents are characterized by having an N—N (N being Nitrogen) bonding in their molecules and boiling points between about 70° C. and about 220° C., and include hydrazine and water solutions, hydrazine derivatives, NitrosAmine derivatives saturated with two hydrocarbon groups selected from Methyl, Ethyl, Propyl and Butyl, NitrosAmine related compounds, and Nitrogen Tetroxide. Preferred agents are Hydrazine monohydrate (HMH), HydroxyEthylHydrazine (HEH), CEH, BocMH, BocMEH, NDMA, NDEA, NMEA, NMPA, NEPA, NDPA, NMBA, NEBA, NPYR, NPIP, NMOR and Carmustine, alone or in combination with Nitrogen Tetroxide. The agents are effective for etching copper in high aspect ratio (deep) holes.
US08894825B2 Sputtering target, method for manufacturing the same, manufacturing semiconductor device
A deposition technique for forming an oxynitride film is provided. A highly reliable semiconductor element is manufactured with the use of the oxynitride film. The oxynitride film is formed with the use of a sputtering target including an oxynitride containing indium, gallium, and zinc, which is obtained by sintering a mixture of at least one of indium nitride, gallium nitride, and zinc nitride as a raw material and at least one of indium oxide, gallium oxide, and zinc oxide in a nitrogen atmosphere. In this manner, the oxynitride film can contain nitrogen at a necessary concentration. The oxynitride film can be used for a gate, a source electrode, a drain electrode, or the like of a transistor.
US08894822B2 Rotary evaporator
A rotary evaporator (1) having a cooler (6), wherein temperature sensors (15, 17) are disposed in the inlet (14) and outlet (16) of the coolant into or out of the cooler (6), and a volume flow rate of the coolant through the cooler (6) is determined. The initiation or termination of condensation in the cooler (6) is derived from an increase or decrease in the difference of the temperatures (X) at the temperature sensors (15, 17). The volume of the condensed distillate (10) is determined from the difference in temperatures (X), and a distillation volume control is performed. By regulating the heating power of the heater (11) and/or the pressure in the system, the loading of the cooler (6) is controlled as a function of the difference in temperatures (X).
US08894810B2 Floating salt farm
A floating salt farm in which its purpose is to produce crystallized salt and bittern at offshore locations through the evaporation process using extracted seawater. The floating salt farm components can be consisted of a seawater tank, an evaporator tank, a heating tank, a deposit tank, a storage tank, and photovoltaic panels, which these components are installed onto the buoyant foundation. The evaporator tank component can consist of an evaporator plate and an evaporator bin. The evaporator plate, which captures the produced crystallized salt during the evaporation process, has a sieve surface. The contents inside the evaporator bin can affect the properties of the produced crystallized salt and bittern, such as their mineral compositions, during the evaporation process. The seawater can be extracted from desired water depths and/or in the proximity of volcanic sites, in which the seawater can have affected mineral compositions due to volcanic activity.
US08894804B2 Plasma unconfinement sensor and methods thereof
An arrangement within a plasma reactor for detecting a plasma unconfinement event is provided. The arrangement includes a sensor, which is a capacitive-based sensor implemented within the plasma reactor. The sensor is implemented outside of a plasma confinement region and is configured to produce a transient current when the sensor is exposed to plasma associated with the plasma unconfinement event. The sensor has at least one electrically insulative layer oriented toward the plasma associated with the plasma unconfined event. The arrangement also includes a detection circuit, which is electrically connected to the sensor for converting the transient current into a transient voltage signal and for processing the transient voltage signal to ascertain whether the plasma unconfinement event exists.
US08894803B2 Apparatus and method for etching the surface of a semiconductor substrate
A process for etching the surfaces of semiconductor substrates utilizes a texturing tank which introduces a process fluid through a circulating system. The process fluid is heated to a desired temperature and maintained at a desired concentration prior to entering a processing area where laminar flow is produced to more quickly and uniformly roughen the surface of semiconductor substrates. The texturing tank permits removal of bubbles and eliminates temperature stratification in the processing area.
US08894802B2 Method for producing composite elements
The invention relates to a method for the production of composite elements comprising at least one outer layer a) and a layer b) firmly bonded to it, an adhesion promoter c) being applied between the outer layer a) and the layer b) firmly bonded to it, the outer layer a) being continuously moved and the adhesion promoter c) and the layer b) firmly bonded to it or the starting materials thereof being applied in succession to the outer layer, the application of the adhesion promoter c) being effected by means of a rotating disk which is mounted horizontally or with a slight deviation from the horizontal of up to 15°, wherein the rotating disk is provided with teeth on the edge.
US08894800B2 Polymeric edge seal for bonded substrates
A layer of polymer material is applied on a peripheral region of at least one of the two substrates to be bonded prior to bonding. The bonded structure formed thereby includes a first substrate, a second substrate in direct contact with the first substrate, and a ring of the polymer material in direct contact with the first substrate at a first interface and in direct contact with the second substrate. The ring of polymer material laterally surrounds and seals the interface at which the first substrate contacts the second substrate. A ring-shaped cavity can be formed within the polymeric ring. Alternately, the first interface and the second interface can be contiguous without a ring-shaped cavity between the first and second substrates.
US08894798B2 Method and apparatus for manufacturing absorbent article
In a case where components such as side flaps and crotch portions are arranged on multiple webs which are being conveyed while being arranged side by side in the width direction of the webs, articles in various sizes can be handled easily by a web conveying step of conveying a front waistline web 11A and a back waistline web 11B the webs being arranged side by side in a width direction of the webs, a flap attaching step of attaching side flaps 30 onto the web 11 of the front waistline web 11A or the back waistline web, a web gap changing step of changing a gap between the front waistline web 11A and the back waistline web 11B by a web gap changing mechanism 500 and a crotch member attaching step of attaching a crotch member 20 between the front waistline web 11A and the back waistline web 11B, wherein the web gap changing step is performed between the flap attaching step and the crotch member attaching step.
US08894792B2 Manufacturing method of functional material using slice stack pressing process and functional material thereby
Disclosed herein are a method for manufacturing a functional material for use in various industrial fields in which anisotropy or physical properties change according to height may be utilized, as well as a functional material manufactured thereby. The method includes the steps of: (1) mixing powders composed of the components of the functional material with a binder to prepare a mixed paste; (2) coating the mixed paste on a substrate, and then separating the coated material from the substrate, thus preparing a slice; (3) repeating step (2) to prepare a plurality of slices, and stacking the slices in a mold; and (4) pressing the stacked slices at a predetermined temperature and pressure. A multifunctional material, such as an anisotropic material having physical properties which change according to the direction of material, or a material having physical properties which change in a graduated manner according to height, may be manufactured in a simple and economical manner.
US08894791B1 Composite rotor blade manufacturing method and apparatus
Apparatus and methods are disclosed for manufacture of a composite structure, such as a composite rotor blade spar or composite rotor blade. A first mold may define a first mold surface and a second mold may include a rigid layer and a heated layer secured to the rigid layer and defining a second mold surface. A plurality of heating elements embedded in the second mold may be activated according to different temperature progressions to cure portions of the uncured composite rotor blade positioned coextensive therewith. In some embodiments, the second mold defines a root portion and first and second branch portions. A shear web placed between the branch portions may be bonded to a blade skin positioned within the mold. The rotor blade may include a rotor blade spar having leading and trailing edge fairings secured thereto or the blade spar may define a complete airfoil contour.
US08894789B2 Method for producing an artificial wood and artificial wood product
The invention relates to a method for producing an artificial wood product from fibers and bonding agent and to an artificial wood product comprising fibers and bonding agent. The objective of the invention is to disclose a new kind of method and a product which allows a production of an artificial wood having an outer appearance just like a natural wood. In the method several fibers are aligned longitudinally to form a strand wire, several said strand wires are bonded with said bonding agent unidirectionally and side by side together to form a fiber sheet, and several said fiber sheets are stacked and bonded with said bonding agent one upon the other in layers to form an elongated wood product in which said sheets replicate the pattern of annular growth rings of a natural wood.
US08894788B2 Decorative element with TPU film and method of its manufacture
A method for producing a decorative element includes the steps of: (a) preparing a thermoplastic polyurethane (abbreviated TPU) film, at least one ornament, and a releasing film coated with a glue layer on a plane thereof; (b) disposing the plane of the releasing film coated with the glue layer facing the ornament; (c) arranging the ornament located between the TPU film and the releasing film to form a stacked array; and (d) hot pressing the stacked array.
US08894784B2 Method of processing a composite patch
A method of processing a patch includes mounting the patch on a surface of a caul plate having at least one suction hole, and drawing a vacuum through the suction hole to maintain the patch in contact with the caul plate.
US08894781B2 Method and apparatus for treating a steel article
A method for forming and treating a steel article of a high strength and high ductility alloy particularly suited for use as armor plate. The method includes the steps of providing a starting material for the steel article, heating the starting material to a peak temperature range in less than ten seconds, holding the heated steel composition at the peak temperature range for between two and six seconds, quenching the heated steel composition from the peak temperature range to below 100° C. (212° F.) at a temperature rate reduction of 400 and 3000° C./sec (752 and 5432° F./sec), removing residual quench media from the surface of the quenched steel composition, tempering the quenched steel composition at a temperature of 100 to 260° C. (212 to 500° F.); and air cooling the tempered steel composition to less than 100° C. (212° F.) to form a steel having desired mechanical properties.
US08894774B2 Composition and method to remove excess material during manufacturing of semiconductor devices
A composition of matter and method to remove excess material during the manufacturing of semiconductor devices includes providing a substrate; applying a metal chelator mixture to the substrate, where the metal chelator mixture comprising a metal chelator and a solvent, where the metal chelator binds to the platinum residue, to render the platinum residue soluble; and rinsing the metal chelator mixture from the substrate to remove the platinum residue from the silicide.
US08894768B2 Apparatus for processing substrate
A substrate processing apparatus that simultaneously forms thin films on a plurality of substrates and performs heat treatment includes: a plurality of substrate holders, each including a substrate support that supports a substrate and a first gas pipe having one or a plurality of injection holes; a boat where the plurality of substrate holders are stacked and including a second gas pipe connected with the first gas pipe of each of the substrate holders; a process chamber providing a space in which the substrates stacked in the boat are processed; a conveying unit that carries the boat into/out of the process chamber; a first heating unit disposed outside the process chamber; and a gas supply unit including a third gas pipe connected with the second gas pipe and supplying a heated or cooled gas into the second gas pipe.
US08894767B2 Flow control features of CVD chambers
Apparatus and methods for gas distribution assemblies are provided. In one aspect, a gas distribution assembly is provided comprising an annular body comprising an annular ring having an inner annular wall, an outer wall, an upper surface, and a bottom surface, an upper recess formed into the upper surface, and a seat formed into the inner annular wall, an upper plate positioned in the upper recess, comprising a disk-shaped body having a plurality of first apertures formed therethrough, and a bottom plate positioned on the seat, comprising a disk-shaped body having a plurality of second apertures formed therethrough which align with the first apertures, and a plurality of third apertures formed between the second apertures and through the bottom plate, the bottom plate sealingly coupled to the upper plate to fluidly isolate the plurality of first and second apertures from the plurality of third apertures.
US08894764B2 Apparatus and method for the selective non-catalytic reduction (SNCR) of NOx in industrial cement production plants
The present invention relates to an apparatus and a method for the selective non-catalytic reduction (SNCR) of NOx in industrial cement production plants. In particular, the method according to the present invention provides for the atomization of an aqueous solution containing the reagent by introducing it into the gas to be treated that is at a high temperature, thus achieving the simultaneous and immediate evaporation of the water and gasification of the reagent. Thanks to this method, there is achieved improved performance of the non-catalytic reduction process of NOx while using the same reagent or, specularly, the same performance with a lesser amount of reagent being required, with consequent reduction of the costs.
US08894762B2 Phase change ink comprising a polyhydroxyalkanoate compound
A phase change ink including an amorphous compound; a crystalline compound; an optional colorant; an optional synergist; an optional dispersant; and at least one polyhydroxyalkanoate compound of the formula wherein R is independently selected from the group consisting of a hydrogen atom, a hydrocarbon group, a heteroatom, and combinations thereof; wherein n represents the number of repeating units of from 1 to about 35,000; and wherein x represents an integer from 1 to about 5.
US08894761B2 Emulsion-based thermal inkjet inks
Emulsion-based thermal inkjet inks include a high boiling point carrier fluid; a colorant; and vesicles comprising a low boiling point expellant fluid, and an ionic surfactant comprising molecules, each having a head with affinity to expellant fluid material and a tail with affinity to carrier fluid, the vesicles having a core defined by the heads of the surfactant molecules, the expellant fluid contained in the core, with the vesicles dispersed in the carrier fluid. A method for preparing the thermal inkjet inks is also disclosed.
US08894759B2 Cogeneration apparatus
A cogeneration apparatus having an engine and an air-cleaning device provided to the engine is disclosed. The air-cleaning device is provided with an air filter and a hollow resonator. The air filter is provided at a position where a space within an air-cleaning case splits into an upstream space and a downstream space, and the resonator is provided to the downstream space and positioned at a predetermined interval with respect to the air-cleaning case. Air is introduced through the downstream space to an internal space of the resonator.
US08894758B2 Gas treating method and apparatus
A method and apparatus for treating natural gas comprises a contactor having a manifold for spreading gas in the contactor vessel, a plurality of perforated plates above the manifold, a spray system for spraying a treating liquid into an upwardly rising column of gas and a liquid level controller for maintaining the treating liquid above the perforated plates. Gas and liquid from the contactor pass through a cooler and are then separated. A treating liquid regeneration system receives the treating liquid and flashes the liquid at low pressure to separate hydrocarbon gases, hydrocarbon liquid and treating liquid. The treating liquid is regenerated by heating and flashing off contaminant gases and is ultimately redelivered to the contactor.
US08894756B2 Collapsible bag vessel with antifoaming device
Disclosed herein are fluid containment systems such as gas delivery configurations, foam control systems and bag molding methods and articles for supported collapsible bag vessels and bioreactors. A vessel may include a device which can reduce the foam produced or contained within the vessel. Sensors and/or controllers may optionally be used to monitor and/or control foaming.
US08894753B2 Carbon dioxide capture systems
Disclosed is a carbon dioxide capture system which includes a first carbon dioxide adsorption/desorption section including a first carbon dioxide adsorption section, a first carbon dioxide desorption section connected to the first carbon dioxide adsorption section, and a first carbon dioxide adsorbent circulating through the first carbon dioxide adsorption section and the first carbon dioxide desorption section; and a second carbon dioxide adsorption/desorption section including a second carbon dioxide adsorption section, a second carbon dioxide desorption section connected to the second carbon dioxide adsorption section, and a second carbon dioxide adsorbent circulating through the second carbon dioxide adsorption section and the second carbon dioxide desorption section.
US08894746B2 Odor killing charcoal box systems
An odor-killing charcoal box system which can eliminate strong odors by absorbing and neutralizing the odors safely and inexpensively thereby improving the air quality in virtually any given interior area. This unique product can comprise a paper cube, which can measure approximately 4″ by 4″ by 4″. The sides of the box can be made of porous, natural breathable fabrics, such as cotton or linen. The box may be opened up on five sides (or less.) By exposing these five sides, the box can create maximum surface area exposure for the activated charcoal powder to absorb odor effectively from the surrounding area.
US08894744B2 System and method of cleaning particulate collection devices used in a flue gas processing system
A system is provided for removing particulate matter from a particulate collection device utilized to collect particulate matter from a flue gas stream. The system includes a pressure vessel for storing a pressurized gaseous medium in an interior area defined by the pressure vessel. A first pressure sensor is in communication with the interior area and configured to measure pressure therein. A particulate collection device for collecting particulate matter from a flue gas stream includes a conduit in communication with the pressure vessel. A valve is disposed in the conduit and adapted to open to release a pulse of the pressurized gaseous medium from the pressure vessel into the particulate collection device. A control system is in communication with the valve and the first pressure sensor, and includes a controller configured to operate the valve based upon at least one pressure measurement received from the first pressure sensor.
US08894743B2 Method for processing flue gas
A method of removing CO2 from an input gas stream, the method comprising reacting a solid sorbent with the input gas stream to remove CO2 from the input gas stream in a carboniser; reacting the solid sorbent from the carboniser in a calciner to release the CO2 into a substantially pure gas stream; exchanging heat between the carboniser and calciner; and controlling a CO2 partial pressure and temperature in the carboniser and a CO2 partial pressure and temperature in the calciner such that the temperature in the carboniser is higher than the temperature in the calciner for providing heat from the carboniser to the calciner.
US08894741B2 Water, light and airflow control system and configuration for a plant air purifier
A plant air purifier and associated method for purifying air, comprising: at least one grow container; a filter bed comprising a surface which is horizontal within 20 degrees of a horizontal plane; at least one plant which grows within the filter bed; a reservoir for containing water for watering the at least one plant; a mechanical watering device which waters the filter bed from the top down; a pump for pumping water from the reservoir to and through the mechanical watering device; and an air propulsion mechanism for propelling air through the filter bed.
US08894737B2 Suspended nutrition composition and manufacturing method thereof
A suspended nutrition composition includes a foamed material, a colloid layer and a nutrient. The foamed material having a plurality of pores includes a starch, a biodegradable polyester and a plasticizer. The pores are formed by bubbles produced from a physical foaming agent. The colloid layer covers a surface of the foamed material. The nutrient is dispersed in the foamed material.
US08894736B2 Gas distributor for granular moving-bed filter
A gas distributor for a granular moving-bed filter comprises a distribution module, arranged inside a granular moving-bed filter. The distribution module comprises at least one flow-distributing curtain to be used for allowing a turbulent gas flow with dust mixed therein to flow therethrough, resulting that before the turbulent gas flow enters the granular moving-bed filter, the turbulent gas flow is transformed into a more uniformly distributed gas flow and the dust contained therein are partially filtered out.
US08894734B2 Cooling air cleaner of an electronic device
The present invention relates to an air cleaner for the removal of pollutants from an air flow by a filter module, the filter module of which includes at least one permeable filter layer for the accumulation of pollutants on the filter layer. A bypass channel will be provided and established such that part of the unfiltered air flow may bypass any filter layer. Such a bypass channel does not compromise the cleaning effect of the filter module, at least as long as the filter layer has not yet been clogged with pollutants since in this case the biggest part of the air flow will take the major path through the filter layer due to lack of resistance. Only if the filter layer is clogged and if resistance for the air flow increases, air will obviously flow through the mentioned bypass channel.
US08894731B2 Abrasive processing of hard and /or brittle materials
Abrasive articles possessing a highly open (porous) structure and uniform abrasive grit distribution are disclosed. The abrasive articles are fabricated using a metal matrix (e.g., fine nickel, tin, bronze and abrasives). The open structure is controlled with a porosity scheme, including interconnected porosity (e.g., formed by leaching of dispersoid), closed porosity (e.g., induced by adding a hollow micro-spheres and/or sacrificial pore-forming additives), and/or intrinsic porosity (e.g., controlled via matrix component selection to provide desired densification). In some cases, manufacturing process temperatures for achieving near full density of metal bond with fillers and abrasives, are below the melting point of the filler used, although sacrificial fillers may be used as well. The resulting abrasive articles are useful in high performance cutting and grinding operations, such as back-grinding silicon, alumina titanium carbide, and silicon carbide wafers to very fine surface finish values. Techniques of use and manufacture are also disclosed.
US08894730B2 Alumina sintered body, abrasive grains, and grindstone
Provided are an alumina sintered compact containing a titanium compound and an iron compound, wherein the total amount of the TiO2-equivalent content of the titanium compound, the Fe2O3-equivalent content of the iron compound and the alumina content is at least 98% by mass, the total amount of the TiO2-equivalent content of the titanium compound and the Fe2O3-equivalent content of the iron compound is from 5 to 13% by mass, and the ratio by mass of the TiO2-equivalent content of the titanium compound to the Fe2O3-equivalent content of the iron compound (TiO2/Fe2O3) is from 0.85/1.15 to 1.15/0.85; and an abrasive grain and a grain stone using the alumina sintered compact.
US08894722B2 Construction of planar rechargeable oxide-ion battery cells and stacks using stainless steel housing structures
Processing steps for constructing a rechargeable oxide-ion battery (ROB) cell using a cell membrane assembly 40 and a hollow metal housing structure 30 wherein assembly steps include: a) forming a membrane assembly 40 of air electrode 20, metal electrode 24 and electrolyte 22 therebetween; b) sealing the membrane assembly 40 to a surrounding frame 26; c) filling the hollow metal housing structure 30 with active material 32; d) forming electrical contact between the framed membrane assembly and the filled housing structure; and e) joining the framed membrane assembly and the active housing structure to form a ROB cell.
US08894720B2 Procedure for the preparation of sulphur-based articles of manufacture
The present invention relates to a process for the preparation of articles of manufacture made of or based on sulphur, which comprises cooling of liquid sulphur in a volume of containment until the sulphur mass solidifies and forming of the product, characterized in that elastic pressure waves are applied to the cooling mass of liquid sulphur to produce a crystalline suspension of solid sulphur in liquid sulphur.
US08894717B2 Surgical prostheses
A prosthesis arranged to be coupled to a bone. The prosthesis comprises a substrate (2) having a surface (6). The surface (6) of the substrate (2) has a first area and a second area, the first area being treated such that osteointegration is promoted more than in the second area. The interface (12) between the first and second areas forms an alignment mark to assist alignment of the prosthesis relative to a bone. The prosthesis is arranged to be at least partially inserted into a bone cavity such that the position of the alignment mark relative to the bone cavity is indicative of the angle of insertion of the prosthesis or the alignment mark provides a position reference for determining the implanted position of the prosthesis in the cavity. A method of manufacturing the prosthesis and a method of implanting the prosthesis are also provided.
US08894715B2 Knee prosthesis
A knee joint prosthesis assembly according to the present disclosure can include a femoral component, a unitary tibial component, a medial bearing, and a lateral bearing. The femoral component can have a medial and a lateral condyle portion connected by a patellar track portion. The femoral component can form an opening between the medial and lateral condyles. The unitary tibial component can have a medial portion that includes a first posterior engagement lip and a first outer securing lip. The tibial component can further include a lateral portion that includes a second posterior engagement lip and a second outer securing lip. The medial bearing can have a first posterior groove formed thereon that selectively engages the first posterior engagement lip and a first outer groove that selectively engages the first outer securing lip.
US08894713B2 Shoulder implant
Apparatus and method for a shoulder implant, for example, for the glenohumeral joint. The implant is expandable and deflatable during implantation. The implant is sized for the glenoid fossa. In an exemplary embodiment of the invention, the selection and/or implantation of the implant include adapting the implant by size and function to a particular patient's need.
US08894712B2 Expandable intervertebral implant and associated surgical method
The present invention provides an expandable intervertebral implant, including: a superior member configured to engage a superior intervertebral body; an inferior member configured to engage an inferior intervertebral body; and an expansion mechanism disposed between the superior member and the inferior member configured to selectively adjust a separation of the superior member from the inferior member; wherein the expansion mechanism includes a proximal wedge structure and a distal wedge structure that are relatively translated between the superior member and the inferior member, wherein the proximal wedge structure and the distal wedge structure are each coupled to the superior member and the inferior member by a plurality of aligned and/or staggered (i.e. nested) track structures and rail structures; and wherein a load-bearing portion of a bottom surface of the superior member is configured to mate vertically with a load-bearing portion of a top surface of the inferior member when the expansion mechanism is undeployed via conformal protruding and recessed features.
US08894708B2 Spinal implant configured for lateral insertion
The embodiments provide a spinal implant that is configured for lateral insertion into a patient's intervertebral disc space. The spinal implant may have a body having a tapered anterior portion and one or more apertures. The tapered anterior portion allows for concomitant distraction of soft tissue during insertion of the implant. In addition, at least some of the apertures are designed to permit a predetermined amount of nutation by a fixation element. The fixations elements that allow nutation enable the fixation element to toggle from one position to another, for example, during subsidence of the implant in situ.
US08894705B2 Balloon mitral spacer
A heart valve implant according to one embodiment may include a shaft and an anchor disposed on one end of the shaft, the anchor configured to engage tissue. The heart valve implant may further include an expandable member disposed over at least part of the shaft, the expandable member comprising a resiliently deformable internal layer and a resiliently deformable external layer disposed over the internal layer, the expandable member defining a chamber and being configured to receive an inflation medium in the chamber to expand the expandable member, the expandable member further configured to deform upon contact with at least a portion of at least one leaflet of a heart valve to at least partially conform to the shape of the leaflet.
US08894703B2 Systems and methods for delivering a medical implant
The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system.
US08894700B2 Abdominal aortic stent
An abdominal aortic stent includes a first sub-stent and a second sub-stent each having a front end. The circumference of the front end of each sub-stent is half of the circumference of the abdominal aorta. When the circumference is gradually reduced to a rear end of each sub-stent, it has entered one side of the bilateral femoral arteries. The rear ends of the sub-stents with full circumference of the cross-sectional area of the femoral artery are included therein. The first and second sub-stents are coated with external removable membrane to compress the sub-stents to generate smaller circumferences. When the removable membrane has been removed, the sub-stents are fully extended to reconstruct the vascular flow path.
US08894696B2 Suprachiasmatic nucleus inducing, melatonin suppressing light emitting device to enhance wake cycle
A light emitting device to awaken or alert an animal by stimulating the Suprachiasmatic Nucleus in the brain to suppress melatonin secretion and change gene expression in the brain. The device can be programmed for an initiation time, color of light, brightness, frequency of pulsating light, and level of gradual intensity. It has the advantage of being silent, does not to disturb other people sleeping in the same room and user is more cognitively alert.
US08894693B2 Orthopaedic fixation component and method
An orthopaedic fixation component attachable to a femur, said femur defining a femur shaft, a femur head and a femur neck extending therebetween, said femur further defining a greater trochanter limiting laterally said femur neck, said orthopaedic fixation component comprising: a shaft section fixation portion and an end section fixation portion extending substantially longitudinally therefrom, said shaft section and end section fixation portions being respectively securable to said femur shaft and said greater trochanter; said end section fixation portion including a pair of end arms, said end arms being configured, sized and positioned to delimit a trochanter receiving recess for substantially fittingly receiving a prominent portion of said greater trochanter.
US08894690B2 Offset connection bone anchor assembly
A bone anchor assembly for coupling an offset bone anchor with a previously inserted spinal fixation element and method of use is provided. Exemplary embodiments of a bone anchor assembly are particularly suited for use in a rod-first spinal surgical technique in which a bone anchor inserted into a patient vertebra may be separated from a previously inserted spinal fixation element by a separation distance.
US08894689B2 Stabilization rod assembly for spine fixation and process of making same
A spine stabilization rod assembly comprises a rod and a sleeve member. The rod has a substantially round cross-sectional profile, a one-piece construction, and a substantially straight longitudinal axis. The rod has a reduced diameter segment between two opposing end segments thereof such that a shoulder is defined between the reduced diameter segment and each one of the end segments. The sleeve member is positioned over the reduced diameter segment of the rod. The sleeve member and the rod are coupled to each other such that translation of the sleeve along the rod causes an end portion of the sleeve to engage a corresponding one of the shoulders for limiting such translation.
US08894687B2 Coupling system for surgical construct
A coupling assembly for use in surgical constructs comprises a first body and a second body. One of the first body and the second body includes a male member and an other of the first body and the second body includes a female member. The male member is sized and shaped to be received within the female member and the female member has an internal bore sized and shaped to receive the male member therein. A raised portion is formed on or attached to the male member. An area of decreased diameter is associated with the internal bore of the female member. The first and second bodies are coupleable to one another by an interference fit when the raised portion of the male member is positioned within the area of decreased diameter associated with the internal bore of the female member.
US08894682B2 PFO clip
Embodiments for a device, system and method for occluding an opening in a septum. Embodiments of the device can include a first control component, a first elongate member that extends from the first control component, a second elongate member, a connecting member that positions the first elongate member adjacent the second elongate member and a retraction member releasably coupled to the first control component. The retraction member can be used to change a relative position of the first elongate member and the second elongate member of the device.
US08894680B2 Balloon catheter
The present invention is primarily directed to a rapid exchange catheter that permits axial movement of an inner conduit within an outer conduit comprising: • an outer conduit; • an inner conduit, suitable for total or partial passage over a guide wire, wherein said inner conduit is movably disposed within the lumen of said outer conduit, wherein the proximal end of said inner conduit is angled such that it pierces the wall of said outer conduit; • means for permitting axial movement of said inner conduit within said outer conduit, such that said movement is not hindered by the passage of the angled proximal part of the inner conduit through said outer conduit; and • means, situated at the proximal end of the outer conduit, for causing axial pushing-pulling movements of said inner conduit.
US08894678B2 Cellulite treatment methods
A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes.
US08894671B2 Hemostatic clip
A hemostatic clip includes: a clip body formed by folding an intermediate section of a belt-like member; and a holding tube. The clip body includes: a first member formed of a first metallic material that is elastically deformable; and a pair of second members that are formed of a second metallic material having a lower elastic strain limit than an elastic strain limit of the first metallic member and are connected to respective both ends of the first member. The holding tube is configured to change an opening width of the clip body by holding part of the clip body in the holding tube.
US08894648B2 Surgical clamping device
A surgical clamping device is provided for receiving distal ends of handles having bone attachment members disposed thereon in a recess disposed in the surgical clamping device. When an adjustment mechanism is in a first state, the distal ends of the handles are able to pivot and, optionally, to move axially within the recess of the surgical clamping device. When the adjustment mechanism is placed into a second state by adjusting the adjusting mechanism, the surgical clamping device applies a clamping force to the distal ends of the handles such that they are fixed within the recess of the surgical clamping device.
US08894647B2 System and method for performing surgical procedures with a reusable instrument module
A surgical instrument is provided including an outer housing shell defining a cavity, the outer housing shell defining an upper outer housing half and a lower outer housing half, wherein the upper outer housing half defines a longitudinal axis and an instrument module selectively insertable into the cavity of the outer housing shell. The instrument module includes an inner housing shell, at least one motor disposed within the inner housing shell, a control board being in electrical communication with the at least one motor and an energy source being in electrical communication with the at least one motor and the control board. The instrument module is inserted into the cavity of the outer housing shell in such a manner that the operative axis of the at least one motor is substantially parallel to the longitudinal axis of the upper outer housing half.
US08894646B2 Sphincter treatment apparatus
An apparatus treats tissue at or near a sphincter. The apparatus has an elongated member having at least one lumen including an inflation lumen, and a basket assembly including a first and a second arm. An inflatable member is coupled to the inflation lumen and has a deployed and a non-deployed state. In the deployed state, the inflatable member expands the basket assembly into contact with tissue. At least one of the first and second arms of the basket assembly has a fluid lumen having an aperture for conveying a fluid from the basket assembly. A source of fluid is coupled to the fluid lumen for conveyance of fluid through the aperture. The fluid can be, e.g., an electrolytic solution, and/or an anti-infection agent, and/or an echogenic media, and/or a steroid, and/or an anesthetic, and/or a medicament, and/or a tissue cooling agent. The source can be a drug delivery device.
US08894641B2 System and method for monitoring ablation size
A system for monitoring ablation size is provided and includes a power source including a microprocessor for executing at least one control algorithm. A microwave antenna is configured to deliver microwave energy from the power source to tissue to form an ablation zone. An ablation zone control module is in operative communication with memory associated with the power source. The memory includes one or more data look-up tables including one or more electrical parameter associated with the microwave antenna. The one or more electrical parameters corresponding to an ablation zone having a radius. The one or more electrical parameters include a threshold value, wherein when the threshold value is met the power source is adjusted to form an ablation zone of suitable proportion.
US08894638B2 Tissue welding and cutting apparatus and method
A surgical apparatus includes an elongated shaft having a pair of relatively movable jaws at a distal end thereof. A first heating element on one of the jaws is adapted to heat up to a first temperature and form a welded region within the tissue, while a second heating element on one of the jaws is adapted to heat up to a second temperature and sever the tissue within the welded region. The first and second heating elements may be provided on the same or opposite jaws. A control handle provided on the proximal end of the elongated shaft includes controls for opening and closing the jaws, and may include an actuator for sending current through the first and second heating elements. The first and second heating elements may be electrically connected in series.
US08894633B2 Modular and cooperative medical devices and related systems and methods
The various embodiments disclosed herein relate to modular medical devices, including various devices with detachable modular components and various devices with pivotally attached modular components. Additional embodiments relate to procedures in which various of the devices are used cooperatively. Certain embodiments of the medical devices are robotic in vivo devices.
US08894632B2 Manually operable portable infusion device
A portable therapeutic fluid delivery device and a method for delivering a therapeutic fluid into a body of a patient are provided. In one aspect the therapeutic fluid delivery device and the method can be implemented using at least one housing securable to the body of the patient, a reservoir coupled to the at least one housing, a therapeutic fluid dispensing mechanism, a memory component, a controller, at least one bolus delivery button configured to signal the controller to initiate the delivery of the therapeutic fluid into the body of the patient; and, an inadvertent initiation prevention mechanism adapted for preventing the patient from activating the at least one bolus delivery button.
US08894623B2 Sterile liquid materials distribution, consumption and material waste disposal method and apparatus
The present invention is directed towards a method and apparatus for packaging or containing, handling and managing of a variety of materials or other contents from a variety of sources which encounter use under various dynamic applications, conditions and for a plurality of purposes. The invention more specifically is directed towards one or more containers or packages, suitably fitted or used for the handling or managing of materials or other contents along one or more cycles or chains of use. The one or more packages or other containers described herein are intended for and/or used in one or more interconnections or associations with not only the “initial purpose” filling, transport, storage, dispensing, pouring, using, releasing of sterile or other fluids or material contents, but also used in association with, and for carrying out, the additional delivering and receiving of said fluids or materials, and receiving and delivering of said fluids or materials via an ingress and egress, by a variety of ways, for a variety of functions and for a plurality of purposes.
US08894617B2 Safety device for an injection device
A safety device for an injection device including a protective sheath driven by a spring, the safety device being capable of taking an injection configuration in which the sheath allows an injection needle to be left uncovered, and a safe configuration in which the sheath enables the injection needle to be covered; retractable catches for retaining the spring, the retractable catches retaining the spring under stress in such a manner as to hold the safety device in the injection configuration; and deactivation mechanism for deactivating the retractable catches, enabling the safety device to take a storage configuration in which the retractable catches are not subjected to stress from the spring.
US08894616B2 Stabilization device
A method and apparatus are disclosed for a stabilization device for maintaining a position of a medical device relative to a body surface of a patient. The stabilization device comprises a support portion that defines a groove for receiving the medical device. The groove is structured to allow for positioning of the medical device at a plurality of angles relative to the body surface of the patient. The groove has opposing wall portions for securing the medical device.
US08894615B2 Introducer sheath and methods of making
An introducer sheath and methods of making the introducer sheath are described. The introducer sheath may include a hub portion and a tubular portion. The hub portion may include a substantially non-planar valve portion in a relaxed state. The valve portion may include an aperture configured to receive a medical device. A hub portion may be formed using a forming device. An aperture may be formed through a distal surface of the valve portion. A valve portion may be formed in a cap defining a cavity sized to elastically receive a proximal end of the hub portion.
US08894611B2 Medical injection device with time delay indicator
The present invention relates to an indicating device for use with medical injection devices for administering a drug into the body of a subject user wherein the indicating device is configured for indicating after administration that a dose of the drug actually has been administered and for maintaining this indication until lapse of a pre-defined time interval. The time delay indicator disclosed is based on a mechanical time delay device and includes a visual indicator that is controlled by the mechanical time delay device for signalling the status of the device during lapse of the pre-defined time interval.
US08894609B2 Bag for mixable liquid solutions
A flexible bag (1) that is partially filled with a basic liquid solution (21) has a first end closure (3) from which a mixing tube (7) extends that is provided with a frangible closure cap (8) and a terminal (9) that is suitable for the connection of a container (22) of active substance (23) to be mixed with the basic liquid solution (21) and a second end closure (5) from which two dispensing tubes (12, 13) extend that are provided with respective frangible closure caps (14, 15). A first dispensing tube (12) has a terminal (18) of the press type and a second dispensing tube (13) has a terminal (19) of the screw type (FIG. 1).
US08894603B2 Ocular delivery systems and methods
Described here are systems and methods for accessing Schlemm's canal and for delivering an ocular device or fluid composition therein. The ocular devices may maintain the patency of Schlemm's canal without substantially interfering with transmural fluid flow across the canal. The fluid composition may be a viscoelastic fluid that is delivered into the canal to facilitate drainage of aqueous humor by disrupting the canal and surrounding trabeculocanalicular tissues. Tools for disrupting these tissues and minimally invasive methods for treating medical conditions associated with elevated intraocular pressure, including glaucoma, are also described.
US08894599B2 Uterine stimulant sticks
The invention discloses a novel uterine stimulant, which is in the form of the stick. The uterine stimulation stick, on administration, helps a woman's uterus to contract, or to increase the frequency and intensity of the contractions. Such medicine can be suitably used to induce (start) or augment (speed) labor; facilitate uterine contractions following a miscarriage; induce abortion; or reduce hemorrhage following childbirth or abortion. The proposed medicine produces normal result for desired purpose, without any significant side effect for the mother or fetus.
US08894598B2 Heel ulcer prevention and cushioning boot
A cushioning boot for bed-ridden patients. The boot includes a thickly-padded leg engaging portion and foot engaging portion with a front opening for easy insertion of a patient foot and leg. A series of stretchable, adjustable closure panels are removably secured to the boot for positioning and inserted leg in the proper orientation and retaining it in place.
US08894597B2 Scapulo-spinal stabilizer with abdominal support for opening the superior thoracic aperture
A scapulo-spinal stabilizer with abdominal support for opening the superior thoracic aperture comprises a shirt-like garment for wearing on the torso, the garment having two elongated, semi-rigid thoraco-lumbar support stays disposed in dual, parallel sheaths in a posterior panel thereof, two posterior flexible scapular straps anchored on and angularly depending from superior shoulder portions of the garment, the scapular straps forming a posterior crossing configuration across the support stays, and anterior ends of the scapular straps detachably attached to opposite lateral ends of an anterior rib margin support disposed on the anterior portion of the garment, the scapular stays, scapular straps and anterior rib margin support stabilizing the posture of a wearer and opening the superior thoracic aperture.
US08894586B2 Snarecoil retrieval device for capturing and retrieving a specimen
A retrieval device for collecting a specimen includes an outer cannula member having an inner lumen and an inner member received within the inner lumen such that the inner member can rotate relative to the outer cannula. The device also includes first and second snarecoil elements that are formed as part of the inner member. Each snarecoil element has an arcuate shape and is attached to an inner surface of the outer cannula. The snarecoil elements being deformable such that rotation of the inner member relative to the outer catheter results in the snarecoil elements collapsing toward a center of the outer cannula member resulting in either the tissue specimen being captured between the two snarecoil elements in one embodiment or being sheared by the two snarecoil elements in another embodiment.
US08894581B2 Performing adaptive frame average process in ultrasound system
There are provided embodiments for performing a frame average process based on a change of a frame rate are disclosed. In one embodiment, an ultrasound system comprises: an ultrasound data acquisition unit configured to sequentially acquire ultrasound data corresponding to a living body; and a processing unit configured to sequentially form a plurality of ultrasound images based on the ultrasound data, estimate a frame average coefficient corresponding to a change of a frame rate based on an ith (i is a positive integer) ultrasound image and an ith frame average image, and perform a frame average process between the ith frame average image and an (i+1)th ultrasound image based on the frame average coefficient to form an (i+1)th frame average image.
US08894577B2 System and method for medical information monitoring and processing
A method of monitoring health parameters of subjects within a defined space and over a period of time includes collecting first data corresponding to a physiological parameter of an ambulatory subject, collecting second data corresponding to a behavioral and cognitive parameter of the ambulatory subject, collecting third data corresponding to an identity and a location of the one of the subjects, collecting fourth data corresponding to the one of the ambulatory subjects from third party sources, generating a data record for the one of the ambulatory subjects based upon the first, second, third, and fourth data, and outputting a modified data record, the modified data record containing portions of the data record, the portions selected based upon an access level of a person requesting the data record and a format of the modified data record selected based upon the access level and community needs.
US08894572B2 Device for examining and surgically operating on body cavities, in particular the anal and vaginal cavities
The device for examining and surgically operating on body cavities, in particular the anal and vaginal cavities, comprises an elongate hollow body (2) exhibiting an insertion portion (3) for at least a partial insertion of the device (1) internally of the cavity and an open portion (4), through which the doctor or surgeon can operate. The hollow body (2) exhibits a longitudinal window (5) through which the pathological site of interest on the cavity wall can be isolated. The hollow body (2) exhibits, along the longitudinal window, a transversal section constituted by a curved sector, ends of which extend in a substantially parallel directions which diverge in such a way as to stretch the affected portion of cavity without invading the viewing space and/or the maneuvering space defined by the hollow body (2).
US08894570B2 Video laryngoscope
A video laryngoscope has a handle and a groove on one side of the handle. The groove is used for guiding a guide wire when the larynogoscope is placed in a patient's mouth. A video camera located near the end of the handle is used to view the area around the glottis. When the guide wire is properly positioned near the glottis, the upper part of the guide wire is disengaged from the groove so as to allow an endotracheal tube to be slipped over the guide wire and to be inserted into part of the trachea through the glottis. When the tube is properly inserted for intubation, the guide wire is removed from the tube. An illuminating light source such as an LED lamp can be installed at the end of the handle to provide illumination for the video camera.
US08894568B2 Normalization and stabilization of balloon surfaces for deflation
A deflation device for use in deflating an inflatable or implantable balloon device, comprising, in combination: an endoscope tube, having a distal end, a proximal end, and a lumen; a cap disposed at the distal end of the endoscope tube and having walls defining a balloon interface chamber; a coring device disposed within the lumen and configured to travel within the lumen such that a distal end of the coring device is extendable beyond the distal end of the cap; wherein the cap is configured to provide a normal surface of a balloon relative to the orientation of the coring device as the coring device is disposed near the distal end of the cap.
US08894565B2 Insertion device, rotating tubular member, and driving unit
An insertion device includes a channel defining portion extended through an inside of an insertion section up to a base portion toward a distal direction and defining a channel that is open to an outside of the insertion section in an opening of an outer peripheral portion of the base portion, and a driving unit extended through an inside of the channel with a driving axis being an axial center and being rotatable in directions around the driving axis when driven. The insertion device includes a driving force receiving portion connected to a gear portion in the opening of the channel, and a support unit supporting the driving unit so that the driving axis is parallel to the longitudinal axis in the gear portion.
US08894563B2 Methods and systems for performing a medical procedure
Method and system for treating a patient using a compressible, pressure-attenuating device. According to one embodiment, the system is used to treat urinary tract disorders and comprises an access device, a delivery device, a pressure-attenuating device, and a removal device. The access device may be used to create a passageway to an anatomical structure, such as the patient's bladder. The delivery device may be inserted through the passageway created by the access device and may be used to deliver the pressure-attenuating device to the anatomical structure. The removal device may be inserted through the passageway created by the access device and may be used to view the bladder and/or to capture, to deflate and to remove the pressure-attenuating device.
US08894562B2 Implantable microphone for hearing systems
An implantable microphone for use in hearing systems includes a housing having a back wall. The back wall has a recess (e.g., blind hole) configured to be coupled to an auditory ossicle. The implantable microphone also includes a membrane coupled to a top portion of the housing and a vibration sensor adjacent to the membrane. The membrane is configured to move in response to movement from the auditory ossicle, and the vibration sensor is configured to measure the movement of the membrane and to convert the measurement into an electrical signal.
US08894561B2 Modular implantable medical pump
An implantable medical pump system can include a blood pump comprising a pump housing defining a passage therethrough and a rotor within the passage. The blood pump further includes one or more elements at least partially contained within the housing adapted to actuate the rotor to drive fluid though the passage. The pump housing includes at least one coupling feature. The system further includes an inflow cannula defining a lumen therethrough. The inflow cannula is adapted to be mechanically coupled to the at least one coupling feature.
US08894556B2 Multi-function handle for weight training machine
A multi-functional handle assembly for an exercise machine includes: a strap arranged in a Figure-8 configuration to form a near loop and a far loop extending in generally opposite directions from a crossing point in the strap; a handle having a cavity formed therethrough, wherein the near loop extends to the near side of the handle and the far loop extends from the far side of the handle, the crossing point of the strap positioned in the cavity; a cushioning cuff attached to the far loop; a bearing member having a slot, wherein portions of the near loop are threaded through the slot, such that the bearing member is slidable relative to the portions of the near loop; and means for attaching the handle assembly to the exercise machine, the means for attaching the handle assembly being attached to the near loop. The handle can be drawn between the bearing member and the cushioning cuff, the strap sliding within the handle, such that the near loop and the far loop change in size with sliding of the handle. Movement of the handle and the bearing member can enable the handle assembly to be used with upper body, triceps extension, and leg/hip exercises.
US08894555B2 Hand-held combination exercise device
In general, various embodiments of hand-held exercise devices that can be used to perform different types of exercises that focus on different muscular groups of the body are disclosed. Specifically, the hand-held exercise devices disclosed herein can be used to perform arm exercises as well as abdominal and core muscle exercises. The hand-held exercise devices can include a first handle and a second handle, which rotate about a central axis relative to one another. The hand-held exercise devices can also include a wheel, which may also rotate about the central axis. Resistance can be applied to the relative rotation of the handles and, optionally, to the rotation of the wheel. The resistance can be selectively varied by a user.
US08894552B2 Strap for adapting a heavy bag to model real-life situations for training
An attachment for a heavy bag to use while practicing power striking techniques in ground fighting. The attachment may be used on a bag that is hanging, resting on a free-standing base, or on a bag that has been removed from the hanger or base.
US08894549B2 Exercise device with adjustable foot pad
An exercise device having a selectively adjustable footpad is disclosed. More specifically, the present invention describes a footpad whose angular orientation is adjustable by a cam having at least two support sides. The cam can be positioned between the footpad and a link arm. The cam can be rotatable about an axis with each support side being a different distance from the axis. The angle of the footpad can be adjusted by selectively rotating the cam so that the footpad is resting on different support sides of the cam.
US08894545B2 Hydraulic control system for an automatic transmission having analog electronic transmission range selection
A hydraulic control system for a transmission includes a source of pressurized hydraulic fluid that communicates with an electronic transmission range selection (ETRS) subsystem. The ETRS subsystem includes an ETRS valve, a park mechanism, a mode valve, a latch valve assembly, and a plurality of solenoids. The ETRS subsystem is configured to provide desired operating conditions during a plurality of potential failure conditions.
US08894544B2 Automatic transmission shift control based on transmission input shaft torque signal
A system and method for minimizing torque disturbances during a shift event for an automatic transmission control actual transmission input shaft torque using a transmission input shaft signal produced by an input shaft torque sensor. The torque sensor provides a signal to a controller that monitors the measured transmission input torque. The torque sensor may be implemented by a strain gauge, a piezoelectric load cell, or a magneto-elastic torque sensor. The system may include a vehicle powertrain having an engine, a transmission coupled to the engine via a torque converter, an input torque sensor coupled to the input shaft of the transmission and a controller configured to control engine torque to cause the measured transmission input shaft torque to achieve a target transmission input shaft torque during the shift event.
US08894540B2 Method and apparatus for controlling engine shutdown in hybrid vehicles
A hybrid vehicle is provided that includes a control system that controls the time required for engine shut down. An electric machine or integrated starter-generator may be used to apply a load to the combustion engine after an engine shut down signal is received. By reducing the time required to shut down the engine in a controlled manner, the catalytic converter can be conditioned by providing a desired volume of air and fuel to the catalyst to reduce emissions and increase fuel economy. If an indication is received that it is no longer desirable to shut down the engine, the engine may be restarted conventionally or started in a quick start mode by refueling the engine is the engine operating at a sufficient speed for a quick restart.
US08894532B2 Arrangement comprising at least one dog clutch
An arrangement comprising at least one dog clutch which is shiftable for coupling and decoupling a shaft and a component at a transmission. An actuating piston (5) is disposed axially movable, at least to some extent, within the shaft for moving a shifting claw (9) of the dog clutch into a disengaged state and an engaged state. The actuating piston (5) can be pressurized, on both sides, with a pressurizing medium so that the actuating piston (5) can be hydraulically actuated in both directions of movement.
US08894530B1 Hypocycloidal crank apparatus
Disclosed is an improved hypocycloidal crank apparatus employing as a stator an internally toothed, continuous, synchronous belt. The apparatus is quiet, easily repaired, and does not require lubrication. It is useful for driving air pumps and the like.
US08894529B2 Journal pin oil supply for gear system
An example journal pin includes a generally cylindrical body disposed on an axis having a supply passage. A first chamber and a second chamber are disposed in the generally cylindrical body and are in fluid communication with the supply passage. A recess on an outer diameter of the cylindrical body is in fluid communication with the first chamber and the second chamber. The first chamber and second chamber are each radially outward of the supply passage and including an outlet to the recess. The first chamber and second chamber each have a first section radially inward of a second section. A cross sectional area of the second section is greater than a cross sectional area of the corresponding first section.
US08894528B2 Powertrain with double epicyclic gear train for a hybrid type motor vehicle
The present invention is a powertrain for a hybrid type motor vehicle comprising an electric machine (22), a thermal engine (10), a speed variation device (14) including an engine epicyclic gear train (26) with a sun gear (36) and a crown (50), each connected to shaft (12) of thermal engine (10) by a controlled clutch (28, 30) and to a fixed portion (48) of the vehicle by a one-way coupling (32, 34), and a motion transmission track (120, 122) for motion transmission to a drive axle (16). The powertrain comprises another epicyclic gear train (96) connecting engine epicyclic gear train (26) to said motion transmission track (120, 122).
US08894526B2 Powertrain for a hybrid electric vehicle
A vehicle powertrain including a planetary transmission including an output, a first member connected an a first power source and a second member connected to a second power source, a brake for alternately releasing the output and holding the output against rotation, a motor including a second output driveably connected to vehicle wheels, and a clutch for opening and closing a drive connection between the output and the vehicle wheels.
US08894523B2 Chainwheel for multi-size crank modules
A chainwheel has a chainwheel body, a first combining hole set and a second combining hole set. The chainwheel body has a center point. The first combining hole set has multiple first combining holes that are formed through the chainwheel body. The first distances between the first combining holes and the center point are equal. The second combining hole set has multiple second combining holes that are formed through the chainwheel body. The second distances between the second combining holes and the center point are equal. The second distance is longer than the first distance. Therefore, the chainwheel can be combined with crank modules of different sizes by the first combining holes and the second combining holes.
US08894520B2 Driven pulley for a continuously variable transmission
The driven pulley is part of a continuously-variable transmission (CVT). The driven pulley comprises two coaxially-disposed sheaves defining between them a belt-receiving groove. It also has at least two axisymmetric ramp surfaces attached to one of the sheaves and at least two axisymmetric followers attached to the other sheave, each ramp surface being engageable by a corresponding one of the followers. At least some of the ramp surfaces are provided on corresponding ramp holders that are independent from the sheaves. A method of modifying the settings of a driven pulley and a method of assembling a driven pulley also disclosed.
US08894519B2 Automatic opening mechanical archery broadhead
Archery broadheads include one or more cutting blades which are folded in when shot from a bow. The blades deploy automatically using stored potential energy upon impact with minimal interaction with the target. The blades are attached to the main body of the broadhead and pivot near the leading or forward edge. The deployment is caused by a plunger tip cam releasing the stored potential energy of an internal spring mechanism and uses only minimal kinetic energy of the arrow to actuate. According to one exemplary embodiment, once actuated, the internal spring slides along a cam shaped part of the blades forcing them open. According to another exemplary embodiment, once actuated, the internal spring operates a slide connecting a toggle-link to the blades forcing them open. In both embodiments, the spring-slide mechanism holds the blades closed during flight, deploys the blades on contact and locks the blades open.
US08894517B2 Sporting goods with graphene material
A racket may include a frame including at least one prepreg layer. The at least one prepreg layer may include reinforcing fibers. The at least one prepreg layer may also include a matrix at least partially surrounding the reinforcing fibers. The at least one prepreg layer may also include graphene material.
US08894510B2 Golf ball dimple profile
Golf ball dimples having a cross-sectional profile shape defined by the envelope of the response of an under damped harmonic oscillator are disclosed.
US08894502B2 Apparatus for housing telemetry, sensing, processing and other electronic components and affixing such apparatus to a golf club
A housing for a sensor includes the sensor; vertical walls surrounding an aperture containing the sensor; a horizontal floor connected to a bottom of the vertical walls, the floor having the sensor located thereon; and a vertical shaft connected to the bottom of the floor and configured to connect the housing to a grip of a golf club. The shaft and at least the horizontal floor define a continuous air passage to vent air pressure from an inside of the golf club to an outside of the golf club.
US08894501B1 Golf club head with luminescent alignment element
In one aspect, golf club heads are described herein. A golf club head described herein can comprise a hitting face, a heel positioned behind the hitting face, a top positioned between the hitting face and the heel, and a luminescent component, wherein the luminescent component is positioned to project a spot of light onto a golf ball at a point on the golf ball tangent to the hitting face of the club head and aligned with the center of the hitting face of the club head.
US08894500B2 Diagnosing method of golf swing
A camera 10 photographs a golf player swinging a golf club to hit a golf ball and the golf club. Image data is obtained by photographing. A calculating part 16 extracts a plurality of frames from the image data. The calculating part 16 determines a check frame in which the golf player is in a predetermined posture from the plurality of frames. The calculating part 16 determines a contour of the golf player from the check frame. The calculating part 16 decides a swing from the contour of the golf player. An extreme value constituting the contour is determined in deciding the swing. A feature point is determined from the extreme value. The swing is diagnosed using the feature point.
US08894493B2 Opt-in proximity alert
A method for alerting a player about a wagering game machine is described herein. In some embodiments, the method can include determining that a wagering game machine is in proximity to the handheld computing device. The method can further include indicating that the wagering game machine is in proximity to the handheld computing device.
US08894492B2 System and method for providing an augmented reality experience
There is provided a system comprising a venue including a mapped physical space; a venue management system configured to control real events occurring within the venue; a transporter designed to transport at least one occupant through the mapped physical space along a known path, the transporter configured to move through the mapped physical space under the control of the venue management system; an augmented reality experience server including a virtual venue generator in communication with the venue management system, the virtual venue generator for producing a virtual venue having a virtual representation of the mapped physical space including virtual events and real events occurring within the venue; the augmented reality experience server configured to provide the at least one occupant of the transporter with an augmented sensory perspective including a selective combination of the real events occurring in the venue and the virtual events produced by the virtual venue generator.
US08894491B2 Multi-stage variable resistance trigger
A multi-stage variable resistance triggers includes an input device comprising a communicative output configured to send control information to a computing device for controlling the computing device. The input device further comprises a multi-stage variable resistance trigger assembly configured to provide a first trigger resistance sub-profile throughout a first stage of a trigger pull and a second trigger resistance sub-profile throughout a second stage of the trigger pull.
US08894489B2 Touch user interface supporting global and context-specific touch gestures that are responsive to at least one finger angle
A user interface method for use with a touch gesture user interface in a system implementing global or universal gestures and application-specific gestures for the control of software executing on a device comprising a touch user interface and a computational processor wherein the touch gestures are responsive to at least one finger angle. In an example implementation, wherein when a gesture with an application-specific association is recognized, the user interface operation is determined by the software application that has a currently active user-interface focus. In an example implementation, a global or universal gesture is used to control the system. In an example implementation, a global or universal gesture is used to control a software application executing on the system. In an example implementation, the user interface operation is context-specific.
US08894487B2 Gaming machine having chair with modular back panel
A gaming system includes a gaming machine and a gaming chair for playing a wagering game. The gaming machine includes at least one display configured to display outcomes of the wagering game. The gaming machine further includes at least one wager input device configured to receive wagers from players. The gaming chair includes a seat assembly attached to a base, a cable harness for providing electrical input, and a backrest assembly having an inner structure and a back housing. The back housing is mounted to the inner structure and has a modular mounting feature for receiving one of at least two modular back panels. The modular back panels are received one at a time and include a non-illuminated back panel and an illuminated back panel. The illuminated back panel has a connector for accepting the cable harness.
US08894486B2 Handheld information processing apparatus and handheld game apparatus
A game apparatus includes a stereoscopic image display device configured to display a stereoscopic image, which is stereoscopically visible by the naked eye, and a planar image display device configured to display a planar image. A touch panel is provided on a screen of the planar image display device. An image of a silhouette of an object in a virtual space is displayed on the planar image display device. The game apparatus causes the object in the virtual space to move according to a touch operation performed on the image of the silhouette displayed on the screen of the planar image display device, and stereoscopically displays the object on the stereoscopic image display device.
US08894482B2 Embedding of games into third party websites
Systems and methods for embedding and tracking revenue from fully operational games into third party websites are disclosed.
US08894479B2 Forage harvester with an arrangement for measuring the harvested material throughput
A forage harvester has an engine which is drivingly connected to a chopper cylinder via first drive belt, and to a first end of a drive shaft of a discharge accelerator. A second end of the drive shaft of the discharge accelerator is drivingly connected to a kernel processor via a second drive belt, is arranged, in the direction of harvested material flow, between the chopper cylinder and the discharge accelerator. The discharge accelerator comprises support disks which extend radially, and paddles. The support disks are attached to a hollow shaft enclosing the drive shaft, and, a sensor is arranged between the drive shaft and the discharge accelerator for the determination of the force transmitted by the drive shaft to the discharge accelerator.
US08894478B1 Environmental improvement system
An environmental improvement system for placement within a room bounded by a floor and a ceiling is provided herein. In one embodiment, the system comprises a duct system that extends through the open volume of the room from the floor to the ceiling. The duct system comprises a base unit at a first end terminating proximate the floor, a support unit at a second end terminating proximate the ceiling, and a duct connecting the base and support units. The base unit defines a first opening, and the support unit defines a second opening. At least one fan is disposed between the first and second openings and draws air from the room into and through the system and discharges the air from the system. The first and second openings are each adapted to selectively act as an intake opening or as a discharge opening.
US08894476B2 System for reducing microbial levels on the hide of an animal
Disclosed is a system for reducing microbial levels on a hide of an animal utilizing a device for contacting the hide of an animal with an alkaline solution having a pH of between about 8 and about 13 after stunning the animal, a second a device for contacting the hide with a second solution that includes one of water, organic acid or hydrogen peroxide and a a device for reusing at least a portion of the alkaline solution or the water/organic acid/hydrogen peroxide.
US08894472B2 Tool for machining surfaces of parts
A tool for machining parts and particularly surfaces of parts includes a machining head and a main, supporting body (3) made of carbon fibers bonded by a polymer binder and additionally contains polyhedral multilayer carbon nanostructures of the fulleroid type having e.g. a layer-to-layer distance of 0.34-0.36 nm, taken in a quantity of 0.05-50 wt % of the mass of the polymer binder. The main body thereby obtains an increased stiffness and strength.
US08894463B2 Toy figure assembly with toy figure and surfboard
A toy figure assembly is disclosed. The toy figure assembly includes a toy figure and a toy surfboard that can be used with the toy figure. In one embodiment, the toy figure can be coupled to the toy surfboard in an upright or surfing orientation that simulates the toy figure surfing on the toy surfboard. In one embodiment, the toy figure can be coupled to the toy surfboard in a lying orientation that simulates the toy figure paddling on the toy surfboard. In one embodiment, a handle is coupleable to the toy figure to allow a user to move the toy figure into different poses.
US08894461B2 System and method for interactive toys based on recognition and tracking of pre-programmed accessories
A system and method for interactive play that includes an object having a visible characteristic such as a color pattern that is recognizable in an image. The color pattern may be associated with an instruction. An imager in a toy captures an image of the object that is processed by a processor in the toy. The processor identifies the visible characteristic and finds the instruction associated with the visible characteristic. The processor may signal an output device of the toy to take an action in accordance with the instruction.
US08894456B2 Compound rotating handle
A paddle apparatus for standup paddling of surfboards or like water craft, having a plurality of hand grip portions rotatably mounted relative to the paddle shaft, and a means of paddling whereby the operator can ergonomically paddle with greater power and control on either side of the water craft without breaking either hand grip. A further improvement includes using the handgrip in the position perpendicular to the paddle shaft to determine the blade position by feel and steer with greater torque. An alternative embodiment includes rotation of the grip itself, further reducing the twisting of the wrists and other joints.
US08894450B2 Connector having a terminal retainer with pressing means
A connector (10) includes a retainer (30) made of synthetic resin for mounting in a housing (11) at a partial locking position for permitting the insertion of a terminal fitting (20) into the housing (11) and at a full locking position for retaining the inserted terminal fitting (20). Locks (16, 35) are formed on the housing (11) and the retainer (30) and are engageable to hold the retainer (30) at the partial locking position. A pressure receiving surface (15) is formed on the housing (11) and is configured to restrict a movement of the retainer (30) toward the full locking position by pressing the retainer (30) in directions intersecting a moving direction of the retainer (30) from the partial locking position to the full locking position when the retainer (30) is at the partial locking position.
US08894449B2 Terminal block
[Problem] To provide a compact terminal block.[Means for solving problem]A terminal block 1 includes: a terminal block main body 2 on which a plurality of seating surfaces 13 are provided; a plurality of fixing members 3 penetrating first and second connection terminals and fixing the first and second connection terminals to the seating surfaces 13 in a manner that the first connection terminals are connected to electronic devices, and the second connection terminals 8 to be electrically connected to the first connection terminals are overlapped with the seating surfaces 13. The seating surfaces 13 are sloped relative to a direction W that the first and second connection terminals are arranged.
US08894444B2 Coaxial electrical connector and coaxial electrical connector assembly including a tubular contact for reducing the height and improving the retention strength against mating or removal
A coaxial electrical connector having a shorter height and improved retention strength against mating and removal with a simple structure is provided. A connector mounting portion P1 is formed as a recess or a through hole in a printed wiring board P, and the connector is mounted such that its insulating housing 11 is inserted into this connector mounting portion P1 of the printed wiring board P, so that the height of the connector is reduced. Load applied when a counterpart electrical connector 20 is mated with or removed from the connector is stably supported by the insulating housing 11 via a connector holding portion 11c, so that components such as conductive contacts are prevented from deformation, and solder joints are prevented from peeling.
US08894443B2 Method of mounting a connector
A board-mountable connector is provided. The connector includes a shield and an insulative housing with a tongue. Terminals are supported by the housing in two rows and the rows extend from a mating interface to a board mounting interface. The terminals may be mounted to the board via surface mount technology in two rows that are at about 0.4 mm pitch. The two rows of terminals are configured in a signal, signal, ground triangular configuration so as to provide a triangular terminal arrangement that extends from the mating interface to the mounting interface.
US08894442B2 Contact modules for receptacle assemblies
A contact module includes a conductive holder and a frame assembly received in the conductive holder with receptacle signal contacts arranged in differential pairs. A ground shield is received in the conductive holder between the frame assembly and the conductive holder. The ground shield has a mounting end with ground pins extending from a mounting edge at the mounting end of the ground shield. Forces are imparted on the ground pins during coupling with a circuit board. The mounting end has a plurality of bearing surfaces proximate to the ground pins. The bearing surfaces engage at least one of the conductive holder and the frame assembly to transfer the forces between the ground shield and at least one of the conductive holder and the frame assembly.
US08894441B2 Cable assembly with new arrangement of terminals
A cable assembly comprises a housing, a plurality of terminals received in the housing and divided into several terminal groups and a cable electrically connected with the plurality of terminals. Each terminal group comprises a pair of signal terminals and a grounding terminal. Each terminal defines a body portion, a mating portion extending forwardly from a front end of the body portion, and a terminating portion extending rearwardly from a rear end of the body portion. The two mating portions of the pair of signal terminals and a mating portion of the grounding terminal of each terminal group are located on two different rows, and two terminating portions of the pair of signal terminals and a terminating portion of the grounding terminal of each terminal group are located on a same row.
US08894439B2 Capacitivly coupled flat conductor connector
A capacitivly coupled flat conductor connector provided with a male connector body and a female connector body. An alignment insert is coupled to the male connector body, the alignment insert dimensioned to support a predefined length of an inner conductor. An alignment receptacle coupled to the female connector body, the alignment receptacle dimensioned to receive a connector end of the alignment insert to seat an overlapping portion of an inner conductor and an inner conductor trace parallel with one another against opposite sides of a spacer.
US08894433B2 Electrical connector assembly with enhanced blind mating features
An electrical connector assembly comprises a first connector unit and a second connector. The first connector unit comprises a first connector having an insulative housing with a plurality of contacts mounted thereon. A printed circuit board, on which the first connector is seated, defines a pair of mounting sections at opposite ends thereof and locate adjacent to the first connector. An insulative cover is attached to a first surface of the printed circuit board which is opposite to the first connector. The insulative cover forms a pair of guiding posts retained in said mounting sections and a pair of stand-off sections located at opposite ends thereof for supporting the first connector during the mating process. A metallic cover is attached to the insulative cover. The second connector defines a pair of guiding apertures at opposite ends thereof for receiving said guiding posts.
US08894432B1 Connector assembly
A connector assembly for fitment to a vehicle. The connector assembly includes a base unit for mounting to a vehicle and an expander unit. The expander unit is configured to attach to and detach from the base unit. The base unit includes a base connector face having at least two opposite edges and having therein a base connector and the expander unit includes an expander connector face having an expander connector. The expander connector is configured to connect with the base connector for communicating a signal therebetween when the expander unit is attached to the base unit. Two pins protrude from the base connector face. Two latch plates are mounted to the expander connector face. The pins and connector have relative positions matching the relative positions of the latch plates and connector so that, with the expander connector connected with the base connector, the pins pass through respective latch plates.
US08894431B2 Connector assembly and corresponding assembly
This connector assembly (4) comprises a connecting plate (12) provided with at least one electrical (16) and/or fluid (14) connection element, which defines a direction of connecting (Z) to a complementary connection element (18, 20), a support (22) and a floating device (26). The plate (12) is able to be displaced in relation to the support (22) in an offset position in a plane (X-Y). The floating device (26) recenters the plate (12) in an idle position in disconnected configuration and comprises a recentering element (28) integral with an element (12, 22) and means of recalling (30) a cam surface (38) of the recentering element (28) in contact with a cam follower surface (40) arranged on an element (12, 22). The surface (38) and/or the surface (40) is inclined (α) in relation to the direction (Z), and the recentering element (28) is mobile according to the direction (Z) in relation to the plate (12) and in relation to the support (22) between the idle and offset positions.
US08894427B2 USB device with a cap
An electronic device, which may be a USB device, includes a body part that is removably connected to a cap. The body part includes a connector for plugging the device into a host computing device. The cap includes a lever part and a main part. The lever part of the cap is attached to the main part and pivots at least partially around a pivot axis. The lever part includes an anchor part on one side of the pivot axis and an unlock part on the other side of the pivot axis. The anchor part includes a hook that engages a cavity in the body part when the cap is connected to the body part. Depressing the unlock part of the cap causes the lever to pivot around the pivot axis thereby disengaging the hook from the first cavity, and thereby releasing the cap from the body part.
US08894424B2 Universal clip apparatus for solar panel assembly
A solar panel assembly attachment apparatus is provided including a strut defining a generally U-shaped channel; an electrically conductive grounding clip; and a panel retainer. Upon insertion of the panel retainer into a housing receptacle of the clip, a clip slot and a panel body slot are aligned to allow passage of the portion of the solar panel frame. Advancing the solar panel frame through the aligned clip slot and panel body slot compresses a spring to secure the solar panel frame while barbs electrically connect and provide a ground to the solar panel frame.
US08894422B2 Socket connector with contact terminal having waveform arrangement adjacent to tail portion perfecting solder joint
An electrical connector includes an insulative housing with a number of through holes extending therethrough, a number of contacts assembled to the insulative housing, and a number of solder balls disposed in the though holes and each is clasped by the tail and insulative housing. Each contact includes a vertical base portion secured to a first side of the through hole, a contact engaging arm extending from a top end of the base portion, and a solder portion extending from a bottom end of the base portion. The solder portion has a wave arrangement below the base portion and projecting from the base portion to a second side of the through hole which opposites to said first side, and a tail extending downwardly from the wave arrangement and capable of moving from the first side to the second side.
US08894415B2 System, method and apparatus for driver training
An application for a system for driver training is includes a computer with at least two graphics displays. A first graphics display simulates a windshield of a target vehicle and a second graphics display simulates a dashboard of the target vehicle. The computer generates images that simulate the dashboard of the target vehicle on the second graphics display. A touch screen interface is connected to the second graphics display and is operatively coupled to the computer thereby signaling the computer with positions of which the second graphics display is touched by a trainee. The trainee is prompted to touch an item on the dashboard (second graphic display) and the touch screen interface is read to determine if the trainee touched the appropriate item (e.g. gauge).
US08894413B2 Architecture, method, and program for generating realistic vehicular mobility patterns
A method, simulator and program for simulating vehicular movement based upon user input parameters related to simulation topology and simulation vehicles including, but not limited to linear vehicular density. The simulator generates the simulation topology having a simulation area using the user input parameters, places a plurality of simulation vehicles within the simulation area at an initial placement using at least two input parameters related to simulation vehicle and the generated simulation topology; and determines movement of the plurality of simulation vehicles starting with the initial placement using a plurality of movement models. Each of the plurality of simulation vehicles has mobility characteristics generated using the plurality of movement models. When vehicle moves outside the simulation area, the vehicle re-emerges at a location within the simulation area. The vehicle re-emerges with new movement characteristics.
US08894412B1 System and method for mechanically activated laser
A firearm simulation system for enhanced firearms training comprises at least one weapon with a mechanically activated laser. The system includes a normally closed laser activation circuit used in conjunction with a recoil kit. The normally closed laser activation circuit comprises a conductive seal, a ball bearing, and a recoil spring. The recoil spring presses or urges the ball bearing into contact with the conductive seal. The function of the laser activation circuit is mechanically triggered and the laser activation circuit is electrically connected to a light source (e.g., a laser light) and configured to activate the light source, simulating a projectile being fired from a weapon. When the trigger of the simulated weapon is pulled, a striker pin dislodges the ball bearing, moving it out of its original position is contact with the conductive seal. The displacement of the ball bearing by the striker pin, away from the conductive seal, creates an open circuit. The open circuit serves to activate the laser, simulating a projectile being fired from the simulated weapon.
US08894411B2 System for preparing and displacing tissue
A dental handpiece to which various tools forming a tool set can be coupled, and more precisely a handpiece coupling, which can be driven by a drive in the dental handpiece at least for an axial oscillating motion The coupling is constituted for a connection of the tools by insertion and securing, and more precisely with a conically tapering opening, into which an adapted coupling section of the tools that tapers in the shape of a truncated cone can be introduced and secured in a suitable manner.
US08894409B1 Colored flame candle
The present invention provides, inter alia, a colored flame candle. This colored flame candle contains: a wick, a body of solid combustible material surrounding the wick except a tip portion of the wick, and a first encapsulated color agent adapted to color a flame of the candle, which color agent is dispersed within the solid combustible material and/or on the wick. Also provided is a wick for a colored flame candle.
US08894407B2 Combustor and method for supplying fuel to a combustor
A combustor includes an end cap, a combustion chamber downstream from the end cap, and a plurality of tubes that extends through the end cap to provide fluid communication through the end cap to the combustion chamber. A casing surrounds the end cap, and a conduit extends from the casing to the end cap. A duct extends around the conduit and inside the end cap to provide fluid communication to the end cap. A method for supplying fuel to a combustor includes flowing a working fluid through a plurality of tubes that extends axially through an end cap, supplying a first fluid through a conduit into the end cap, and supplying a second fluid through a duct spiraling around the conduit into the end cap.
US08894404B2 Blowing mold array, stretch blow molding machine and method
A blowing mold array includes a blowing mold unit forming a cavity, inside of which plastic preforms are expanded to plastic containers. The blow mold unit includes a blowing mold retainer having at least two mold retainer elements for accommodating parts of the blowing mold unit, and a locking mechanism to arrest at least one part of the blowing mold unit against at least one mold retainer element. The locking mechanism includes an engagement element that can be pivoted and/or shifted relative to a default axis, which in an arrested state abuts a segment of a part of the blowing mold unit. The locking mechanism has an actuating element to loosen the arrest between the mold retaining element and the blowing mold unit. Actuation of the actuating element is coupled with actuation of the engagement element.
US08894402B2 Apparatus for vacuum foaming containers for refrigeration
An apparatus for vacuum foaming containers for refrigeration of foodstuffs, in which a polyurethane mixture is injected into hollow walls of a container closed under vacuum condition within a foaming cell. The apparatus includes a main frame for supporting the foaming cell, and an auxiliary frame movable between a lowered opening position and raised closing position of the foaming cell. The foaming cell includes a pallet for supporting a container to be foamed, side shore panels, transversal shore panels, and an internal shore plug member supported by the main frame. The side panels are hingedly connected to slides transversally movable with respect to the auxiliary frame for enabling their distance to be adjusted.
US08894400B2 Stereolithography machine for producing a three-dimensional object and stereolithography method applicable to said machine
A stereolithography machine (1) includes: a container (2) suited to contain a fluid substance (3) that solidifies through exposure to predefined radiation (4a); an emitter (4) suited to emit the predefined radiation and to solidify a layer of the fluid substance having a predefined thickness and arranged adjacent to a bottom of the container; a modelling plate (5) supports the solidified layer (6); an actuator (7) that moves the modelling plate perpendicular to the bottom of the container; a leveler (8) in contact with the fluid substance, associated with a power source suited to move them with respect to the container so as to redistribute the fluid substance in the container. The power source moves the container in each one or the two opposite senses of a direction of movement (Y) and the leveler includes two paddles (9, 10) that are opposite each other with respect to the modelling plate.
US08894393B2 Oil pump for vehicle
An oil pump for a vehicle including a sealing apparatus is provided for preventing leakage of oil from the regulator chamber. The oil pump includes a sealing chamber formed between the outer ring and the housing, a sealing apparatus disposed in the sealing chamber, and an oil passage formed in the outer ring to facilitate a fluid communication of the sealing chamber with the regulator chamber. The sealing apparatus includes a contact portion, first and second sealing members. The first sealing member closely contacts the contact portion if the second sealing member is pushed by the hydraulic pressure of the regulator chamber supplied thereto through the oil passage, and thus prevents leakage of oil from the regulator chamber.
US08894388B2 Compressor having first and second rotary member arrangement using a vane
A rotary compressor is provided that includes an electric motor that supplies electric power and a compression mechanism that compresses a refrigerant while first and second rotary members rotate upon receipt of the electric power from the electric motor. More particularly, the compressor has a compact design by forming a compression space within the compressor by a rotor of the electric motor that drives the compressor, maximizes compression efficiency by minimizing friction loss between rotating elements within the compressor, and has a structure that minimizes leakage of the refrigerant within the compression space.
US08894383B2 Reciprocation compressor
[Object of the Invention] An object of the present invention is to provide a reciprocation compressor comprising an extraction passage connecting a crank chamber with an inlet chamber, an aperture disposed in the extraction passage and a filter capturing foreign matters flowing from the crank chamber to the inlet chamber, wherein the foreign matters captured by the filter is restrained from returning to the crank chamber even if reverse flow of refrigerant from the inlet chamber to the crank chamber is generated, and the filter does not restrict design specifications of other members of the compressor.[Disclosure of the Invention] A reciprocation compressor comprises an extraction passage connecting a crank chamber with an inlet chamber, an aperture disposed in the extraction passage and a filter capturing foreign matters flowing from the crank chamber to the inlet chamber, and the filter is located downstream of the aperture in relation to the flow of the refrigerant in the extraction passage from the crank chamber to the inlet chamber, and the filter is disposed in the inlet chamber.
US08894382B2 Handheld blower apparatus
A handheld blower apparatus includes a housing (2), an axial blower (6) which conveys air through a blower tube (7), and an electric drive motor (4). The drive motor (4) has a rotor (22) and a stator (21) and rotatably drives a drive shaft (16) and at least one fan wheel (23) of the axial blower (6). A simple construction results when the drive shaft (16) is rotatably mounted in the housing (2), when the rotor (22) of the drive motor (4) is connected to the drive shaft (16) in a rotatably fixed manner and the stator (21) of the drive motor (4) is rotatably mounted on the drive shaft (16). The stator (21) is supported relative to the housing (2) to prevent rotation and can tilt in a limited manner relative to the housing (2).
US08894378B2 Systems, methods, and apparatus for sealing a bucket dovetail in a turbine
Certain embodiments of the invention may include systems methods, and apparatus for sealing a bucket dovetail in a turbine. According to an example embodiment of the invention, a method is provided for sealing a gap between a bucket dovetail and a rotor wheel slot. The method can include providing a bucket tab associated with a bucket dovetail, wherein the bucket tab is configured to accept a seal tab; configuring the bucket tab and the seal tab to engage at least one dimension upon insertion of the seal tab into the bucket tab; and sealing a gap between the bucket dovetail and a rotor wheel slot with the seal tab; wherein at least a portion of the seal tab changes as a function of temperature for further sealing gap between the bucket dovetail and the rotor wheel slot.
US08894372B2 Turbine rotor insert and related method of installation
Systems, methods and devices adapted to ease installation of turbine bucket assemblies about a rotor and to reduce related stress concentrations in the rotor are disclosed. In one embodiment, an insert includes: a base portion adapted to complement an entry slot in a rotor of a turbine; and a neck portion extending radially outboard from the base portion, the neck portion adapted to complement a post of the rotor to form a substantially continuous dovetail about the rotor.
US08894370B2 Turbine blade retention system and method
A retention system retains a turbine blade dovetail in a retention ring dovetail slot. The retention system includes a retention opening formed in the blade dovetail. A through hole is formed in the retention ring, wherein the through hole is positioned such that it is aligned with the retention opening when the dovetail is assembled in the dovetail slot. A connector is disposed in the through hole and engages the retention opening. In this manner, undesirable relative movement of parts can be reduced or eliminated, thereby preventing excessive wear.
US08894367B2 Compound cooling flow turbulator for turbine component
Multi-scale turbulation features, including first turbulators (46, 48) on a cooling surface (44), and smaller turbulators (52, 54, 58, 62) on the first turbulators. The first turbulators may be formed between larger turbulators (50). The first turbulators may be alternating ridges (46) and valleys (48). The smaller turbulators may be concave surface features such as dimples (62) and grooves (54), and/or convex surface features such as bumps (58) and smaller ridges (52). An embodiment with convex turbulators (52, 58) in the valleys (48) and concave turbulators (54, 62) on the ridges (46) increases the cooling surface area, reduces boundary layer separation, avoids coolant shadowing and stagnation, and reduces component mass.
US08894366B2 Francis-type hydraulic turbine wheel equipped with a tip-forming member, and method of reducing fluctuations using such a wheel
This wheel comprises a plurality of vanes (2) arranged on a crown (3) and is equipped with a tip-forming member (10) attached to a central region (32) of the crown or hub of the wheel (1), radially inside the vanes (2), the crown defining a wet surface (31) for guiding a flow (E) passing between the vanes. The tip-forming member (10) is provided with at least one opening (121) for diverting a fraction (E1) of the flow towards the internal volume (V10) of this member. This member comprises a frustoconical annular skirt (11) and at least one fin (15) arranged in its internal volume (V10) and able to modify the path of the flow fraction (E1) entering this volume through the opening (121). This fin (15) extends as far as the edge (112) of the skirt (11) which defines an outlet opening (14) of the member (10) for the flow fraction (E1).
US08894359B2 Gas turbine engine with outer case ambient external cooling system
A thermal barrier/cooling system for controlling a temperature of an outer case of a gas turbine engine. The thermal barrier/cooling system includes an internal insulating layer supported on an inner case surface, the internal insulating layer extending circumferentially along the inner case surface and providing a thermal resistance to radiated energy from structure located radially inwardly from the outer case. The thermal barrier/cooling system further includes a convective cooling channel defined by a panel structure located in radially spaced relation to an outer case surface of the outer case and extending around the circumference of the outer case surface. The convective cooling channel forms a flow path for an ambient air flow cooling the outer case surface.
US08894352B2 Ring segment with forked cooling passages
A ring segment is provided for a gas turbine engine includes a panel and a cooling system. Cooling fluid is provided to an outer side of the panel and an inner side of the panel defines at least a portion of a hot gas flow path through the engine. The cooling system is located within that panel and receives cooling fluid from the outer side of the panel for cooling the panel. The cooling system includes a plurality of cooling fluid passages that receive cooling fluid from the outer side of the panel. The cooling fluid passages each have a generally axially extending portion that includes at least one fork. The fork(s) divide each cooling fluid passage into at least two downstream portions that each receives cooling fluid from the respective axially extending portion.
US08894346B2 Skid steer loader blade control
A work vehicle includes a motor associated with selectable movement of a frame by a first operator control. The frame structurally carries a cab structure and a manipulating structure associated with an implement for performing work. The manipulating structure is selectably movable by a second operator control located in the cab structure. All control functions associated with positioning the implement with respect to three different rotational axes are manipulable using the second operator control.
US08894342B1 Automatically retractable boarding ramp assembly for a marine vessel
A retractable boarding assembly for use with a marine vessel mounted on a boat lift includes an elongate ramp pivotally mounted to a dock or other structure adjacent to the boat lift and supported boat. There is a directional pulley supported above a body of water adjacent to the dock. An elongate cable or marine rope engages the pulley. A first end of the cable is secured to a lift platform of the boat lift. An opposite, second end of the cable is secured to the ramp. Raising the boat lift with a boat supported thereon allows the ramp to pull the attached cable across the pulley until the boarding ramp is pivotally deployed to engage a deck of the supported boat. Alternatively, when the boat lift is lowered to introduce the boat into the water, the lift platform pulls the cable through the directional pulley such that the boarding ramp is pivotally retracted and disengaged from the deck of the boat.
US08894337B2 Fastener with display receptacle
The present disclosure illustrates a fastener with an arrangement on the head of the fastener for receiving a medallion, coin or other flat commemorative or decorative item. A threaded stud is secured to a cap which includes a receptacle on a rear surface, complimentary to the head of the stud, and a display pocket on a forward or outer surface for receiving the medallion or coin. The receptacle on the rear side of the cap includes an upstanding rim or lip having an inside diameter slightly larger than the outside diameter of the head of the stud. In the disclosed embodiments, the cap is secured to the stud by swaging or deforming the rim against the head of the stud to rigidly and permanently attach the cap to the stud, forming a fastener with an enlarged head.
US08894332B2 Method for securing a motor vehicle to a transporter
A method for transporting a vehicle having a wheel and a flexible underbody component, such as an air dam or skirt, adjacent the wheel. A chock including at least one wheel positioning bump is placed on a deck of the transporter vehicle (railway car, road vehicle, ship, aircraft, etc.) with the bump projecting upwardly from the deck to contact the wheel when the vehicle is in a pre-tie-down position. The chock further includes a sloped portion extending from positioning bump(s) to be located between the flexible underbody component and the deck. As the vehicle is urged downwardly to a tied-down position, the flexible underbody component contacts the sloped portion and is deflected either away from or toward the wheel to protect it from damaging contact with the deck.
US08894329B1 Wedge anchor bolt
A wedge anchor bolt having a screw member, a wedge member, and a cage member. The bolt is anchored into a drilled hole by wedging the wedge member in the end of the cage member by turning the screw member, with the result being that the wedge member becomes stuck in the cage member. For ejecting the wedge member from the cavity the screw member includes at least one of (1) one or more depressed portions, and (2) one or more projecting portions, defining a step, and the cage member includes one or more corresponding step-engaging portions for making an interference contact with the step, so that further withdrawal of the threads ceases to withdraw the threads relative to the cage member while continuing to withdraw the threads relative to the wedge member, thereby forcing the wedge member distally relative to the cavity.
US08894327B2 Method of reeling and unreeling an internally clad metal pipeline
A method is disclosed for reeling or unreeling a pipeline having an inner corrosion-resistant metallic liner that is tightly fitted within the pipeline. To minimize or avoid wrinkling of the liner during the reeling or unreeling, a length of the pipeline is internally pressurized in a two-stage pressurizing process, and then the length of pipeline is reeled or unreeled, as the case may be. In the first stage of the pressurizing process, the length of the pipeline is filled with fluid at an elevated pressure, and in the second stage the fluid pressure is raised to a higher pressure, which may be 25 bars or more, absolute.
US08894325B2 Submerged hydrocarbon recovery apparatus
A submerged hydrocarbon recovery apparatus for the collection and conveyance of fluids from sub surface leaks to the water body surface. The apparatus comprises a hydrocarbon fluid collector having an opening for receiving and collecting fluids emanating from an underwater hydrocarbon leak; a floatation assembly located below the water surface at a depth not affected by surface disturbances; and a conduit extending between the fluid collector and floatation assembly. The apparatus includes components to prevent the formation of hydrates or accumulation of solids that would obstruct the conveyance of fluids.
US08894324B2 Drainage system, apparatus, and method
Embodiments of the invention provide a drainage system for draining surface liquids from a first surface adjacent to one side of a drainage channel and for providing a transition from the first surface on one side of the drainage channel to a synthetic turf surface or other thick surface material on the other side of the drainage channel.
US08894320B1 Diesel recovery system and method
The apparatus and method provide for the removal of well fluids from well cuttings and a method of disposal thereof. A vibratory separator mechanically shakes the well fluids from the cuttings into a first compartment and the well cuttings fall into a second compartment. Once the well cuttings are dried, cement kiln dust (CKD) is added to neutralize any remaining well fluids on the well cuttings. The neutralized well cuttings are applied to the roadbed of a gravel or dirt road.
US08894317B2 Ball joint and method for the production thereof
A ball joint with a housing formed entirely by a cold forming method. The housing having an inner chamber for receiving the joint ball of a ball pin and an opening through which the ball pin extends, and a contact area on the outer surface area of the housing forms a seal with a bellows. A forming section of the housing secures the joint ball within the inner chamber such that the joint pall can both rotate and pivot. Following completion of the housing, the material displaced during the cold forming method creates the forming section of the housing. The method for producing a ball joint comprises the steps of producing a metallic housing blank with a thickening formed by compression, forming the outer contour of the housing by compression, shaping the inner contour of the housing through dishing, and using the displaced material for creating the forming section.
US08894313B2 Consumer care packaging
A package for a consumer care composition. The package comprises a container containing a consumer care composition, the container having a base for standing the package on a surface, a body portion above the base, a neck portion above the body portion, and a dispensing head above the neck portion. The body portion is aligned along a first axis and the neck portion is aligned along a second axis which is inclined to the first axis so that the dispensing head is directed upwardly and laterally towards a front of the container. The neck portion and the dispensing head have an exterior periphery which is not equal to that of the body portion.
US08894311B2 Eyeliner applicator
An applicator for eyeliner having a stem and an applicator endpiece carried by the stem, the endpiece being of elongate shape along a longitudinal axis and including a flexible zone that deforms while the applicator is in use and that has first and second dimensions dx and dy respectively along first and second axes that are perpendicular to each other and perpendicular to the longitudinal axis of the endpiece, the first and second dimensions dx and dy being substantially equal; the endpiece including a head extending the flexible zone, the head being connected to the remainder of the endpiece solely via the flexible zone, the head being flat in a plane containing the longitudinal axis and the second axis, and measured parallel to the second axis having a maximum width that is greater than the second dimension dy.
US08894307B2 Printing apparatus, printing method and computer readable recording medium storing control program for printing apparatus
There is provided a printing apparatus, including a printing head that prints on a tape, a roller that conveys the tape, and a control circuit that inquires of the user whether or not second printing contents are printed on the tape continuously without any interruption after the printing device is caused to print first printing contents on the tape.
US08894290B2 Retaining cage for the rolling elements of a rolling-contact bearing
A retaining cage for the rolling elements of a rolling-contact bearing, having an annular body featuring seven pockets capable of restraining seven respective rolling elements of a rolling-contact bearing, the rolling elements being spaced apart around a center (O) of the cage, the pockets being spaced from one another according to the following values of angular spacing between two consecutive pockets: 48.3°; 48.5°; 51.2°; 51.8°; 53°; 53.5°; 53.7°.
US08894284B2 System, method, and apparatus for holding a track to a base
A support base for securing a linear motion guide track in a defined location comprises an elongated support body having one or more receiving slots, each slot including inwardly extending deformable teeth-like protrusions that deform upon insertion of the guide track into the slot thereby firmly securing the guide track to the support base without the use of traditional fasteners.
US08894281B2 Lifting bag
A lifting bag having at least one side wall and a closed bottom forming an interior, the bag further having a closable top portion connected to the sidewall and adapted to close the interior of the bag. The opening is a single slit centered on the bag top and closable with a zipper. The lifting bag includes a sling coupled to the bag, generally through a edge strip positioned at ore near the top edge of the bag. The bag can be constructed from a single multilayered sheet. The bag is used in conjunction with a lifting strap system.
US08894278B2 Automated dewpoint oxygen measurement system
An apparatus and method to automate the process of measuring and verifying trace gas levels such as oxygen and dewpoint inside a retort used to coat or heat treat substrates are provided. The apparatus may include an integrated measuring system, and an operator interface. The method may include coupling the apparatus to the retort in which the substrate is coated or heat treated, activating the integrated measuring system to measure and verify atmospheric conditions within the retort, and providing operator access to process parameters and status through the operator interface. The measurement and verification system may be completely autonomous.
US08894275B2 Timepiece barrel
Timepiece barrel for pivotal assembly between a bottom plate and a bridge and including at least one spring housed between a pivoting drum and a ratchet and hooked between this drum at the outer end thereof and an arbour at the inner end thereof, this arbour pivoting integrally with this ratchet about a pivot axis. This barrel includes a single-piece sub-assembly, coaxial with this arbour and grouping together around a hub, this arbour and this ratchet in immediate proximity to this bottom plate, and which is pivoted on an upper shoulder in a bore of this drum on an end pipe whose outer shoulder pivots in a bore of this bridge or of a jewel comprised in this bridge.
US08894274B2 Valve switch modulation for reducing errors due to oscillations of the inlet fluid of a pump system
Described is a method of reducing liquid composition errors in a low-pressure mixing pump system. Packets representing the switching intervals of each component of the desired fluid mixture are provided to an intake of the mixing pump system. For each packet, a switching time associated with at least one of the components in the packet is modulated. Modulated switching times are based on time offsets that are specifically selected according to the undesirable frequency characteristic of an intake response of the mixing pump system. The average of the volumes contributed by the packets thus modulated is equal to a component volume that achieves a desired proportion of the component in the output flow of the mixing pump system. Modulated switching times enable the reduction or elimination of composition error in the output flow of the mixing pump system.
US08894268B2 LED lightbulb
An LED lightbulb is configured to properly illuminate a broader region. The LED lightbulb includes a light emitting unit, a pedestal, a power source unit, a heat dissipator, a base, and a globe swelling toward one side in a first direction for enclosing the light emitting unit. The globe is configured to diffusingly transmit light from the light emitting unit. The light emitting unit provides a light amount not less than 50% of the maximum light amount in a region not exceeding ±60° about the central axis extending in the first direction set as 0°. The globe provides a light amount not less than 50% in a region exceeding ±125° about the central axis set as 0°.
US08894267B2 Panel display device, back frame and manufacturing of back frame
The present invention provides a panel display device, back frame and manufacturing method for back frame. The back frame includes at least two main splicing elements forming back frame, the at least two main splicing elements including main splicing element for disposing light source, wherein light source is disposed on a surface of side wall of main splicing element bended upward for light source disposition, downward hooks are disposed on the other surface of side wall away from light source, main splicing element with light source has a first heat-dissipation capability, and remaining main splicing elements of the at least two main splicing elements without light source have a second heat-dissipation capability, first heat-dissipation capability is better than second heat-dissipation capability. As such, the present invention can reduce material and mold costs as well as better heat-dissipation and easy assembling of front frame and panel.
US08894266B2 Light guide device
A light guide device is provided. The light guide device includes a light guide plate and a light source. The light guide plate includes an incident plane, a bottom plane and a top plane. The bottom plane includes a reflective plane and an inclined bottom plane, wherein the inclined bottom plane connects the bottom of the incident plane and the reflective plane, and the inclined bottom plane is inclined relative to the reflective plane. The top plane includes an inclined top plane, a light-emitting plane and a connecting plane, wherein the inclined top plane connects the top of the incident plane and the connecting plane, the connecting plane connects the inclined top plane and the light-emitting plane, and the inclined top plane is inclined relative to the connecting surface. Furthermore, the light source is located next to the incident plane.
US08894264B2 Spread illuminating apparatus
A spread illuminating apparatus includes: a light guide plate with an emitting surface, a plurality of optical sheets laminated on the emitting surface, a light-blocking member that defines an effective area of the emitting surface, a light source, and a frame for accommodating the above constituents. The plurality of optical sheets are formed such that a position of an edge of each optical sheet on the incident light surface side of the light guide plate is spaced farther apart from the incident light surface of the light guide plate as moving toward a top layer of the optical sheets counted from the emitting surface, and the light-blocking member is fixed to each optical sheet and extends from the incident light surface side of the light guide plate so as to cover a vicinity of the edges of the plurality of optical sheets.
US08894262B2 Blood glucose test strip illumination device and method
A handheld test strip illumination device includes a housing. A strip connector positioned within the housing receives a first portion of a test strip in a test strip test position. A light source is positioned within the housing. A lens/light reflecting device is aligned to receive photons emitted from the light source and direct the photons onto the first portion of the test strip within the strip connector. The first portion of the test strip within the strip connector includes a longitudinal transparent layer receiving the photons emitted from the lens/light reflecting device within the housing. The photons pass through the longitudinal transparent layer and are emitted from the longitudinal transparent layer in a second portion of the test strip positioned outside of the housing, thereby illuminating a dose area of the test strip.
US08894259B2 Dark field illuminator with large working area
An illuminator is described which may be used with large inspection areas and which provides a dark field illumination pattern that is spatially uniform, illuminates from consistent angles, has high efficiency, and is smaller than existing solutions. A light pipe has a first end proximate an object to be illuminated and a second end opposite the first end and spaced from the first end. The light pipe also has at least one reflective sidewall. The first end of the light pipe includes an exit aperture and the second end has at least one opening to allow at least one image acquisition device to view the surface therethrough. At least one light source is configured to provide illumination in the light pipe. The object is illuminated by the first end of the light pipe by illumination at a selected elevation angle and substantially all azimuth angles.
US08894257B2 Headlamp featuring both low-beam and high-beam outputs and devoid of moving parts
A headlight produces low-beam and high-beam outputs without requiring moving parts. Low-beam LED array (7) near first focus (F1) of ellipsoidal reflector (3) directs light laterally against reflector (3) which directs it toward second focus (F2) of reflector. Cut-off edge (4; 5; 63) near second focus forms a bright/dark edge in low-beam output. Cut-off edge is a vertically-oriented light baffle (4) whose top edge forms the bright/dark edge. Cut-off edge is a horizontal light occluding member (16) whose front edge (63) forms bright/dark edge. Cut-off edge is a corner of a heat sink (200). Cut-off edge is located near focal point of lens (2) which transmits low-beam output with a bright/dark edge. Stationary folding mirror (5) near second focus of reflector directs light from high-beam LED array (8) to lens (2). Additive light reflecting from folding mirror (5) transmitting through lens (2) forms high-beam output lacking a bright/dark edge.
US08894256B2 Motor vehicle window having frame with electrical illumination means
A motor vehicle window includes a door frame having a U-shaped top portion defining a channel with outer and inner lips joined by a base wall, and at least one electrically powered light source attached to an outer surface of the inner lip and configured to project light through the window on to the outside of the door. The lights are electrically connected to the car's electrical system and can be illuminated to provide various signals, such as hazard warnings or directions signals.
US08894255B1 Model airplane illumination system
A model airplane illumination system is disclosed. The system includes a plurality of carbon fiber wingtip rods, a wingtip mount configured to secure at least one of the wingtip rods substantially perpendicular to each wingtip of a model airplane, and a plurality of light emitting diodes (“LED”), where at least one LED of the plurality of LEDs is secured to each end of the wingtip rods and configured to illuminate surfaces of the model airplane. In addition, the system includes a carbon fiber tail rod, a tail mount configured to secure the tail rod to a tail of the airplane and configured to illuminate the surfaces of the airplane, and at least one LED of the plurality of LEDs is secured to each end of the tail rod and configured to illuminate the tail and fuselage surfaces of the model airplane.
US08894254B2 Luminaire and lamp apparatus housing
According to one embodiment, a lamp apparatus includes a light-emitting module, housing, and a lighting circuit. The light-emitting module includes a light-emitting element. The housing opens in the direction of irradiation of a light beam and having a cap on a side opposite from the direction of irradiation of the light beam. The cap is provided with a light-emitting module mounting portion projecting in the direction of irradiation of the light beam and the light-emitting module is mounted on the light-emitting module mounting portion. The lighting circuit is accommodated in the housing.
US08894253B2 Heat transfer bracket for lighting fixture
The present disclosure relates to a heat transfer bracket that is configured to mount to a lighting fixture, which includes a heat spreading structure that is formed from a material that efficiently conducts heat and a light source and control electronics that are thermally coupled to the heat spreading structure. The heat transfer bracket includes a base that is thermally coupled to the heat spreading structure of the lighting fixture and multiple petals that extend from the base, wherein heat generated from the light source and control electronics is transferred to the heat spreading structure and from the heat spreading structure to the base of the heat transfer bracket. The heat is then further transferred along the plurality of petals.
US08894250B2 Illuminating device
In an illuminating device, when exiting lights come out from a lens sheet, the optical paths of the exiting lights are deflected in a direction opposite to an optical axis of a light source by means of a plurality of prisms which are included in a first lens group arranged on an inward side of the lens sheet located adjacent to the optical axis of the light source and each of which has a inclined face facing toward the optical axis of the light source, wherein the exiting lights from the light source via the first lens group of the lens sheet are adapted to mix with exiting lights from the light source via a second lens group located outside the first lens group, whereby the degree of color unevenness is reduced, that appears inherently when a pseudo white LED is used as the light source of the illuminating device.
US08894249B2 LED module and method of bonding thereof
The present disclosure provides a method including providing a light-emitting diode (LED) device (e.g., a LED element and PCB) and a heat sink. The LED device is bonded to the heat sink by applying an ultrasonic energy. In an embodiment, the bonding may form a bond comprising copper and aluminum. The PCB may be a metal core PCB (MC-PCB).
US08894246B2 Light emitting apparatus and light emitting unit
A fluorescent lamp type light emitting apparatus is provided. The light emitting apparatus comprises a cover, a light emitting module, radiation pads, and cap parts. The cover comprises a first cover and a transmissive second cover coupled to the first cover. The light emitting module comprises a plurality of light emitting diodes in the cover. The radiation pads are disposed on the light emitting module. The cap parts comprise electrode terminals at both ends of the cover.