Document Document Title
US08866169B2 LED package with increased feature sizes
A light emitter package having increased feature sizes for improved luminous flux and efficacy. An emitter chip is disposed on a submount with a lens that covers the emitter chip. In some cases, the ratio of the width of the light emitter chip to the width of said lens in a given direction is 0.5 or greater. Increased feature sizes allow the package to emit light more efficiently. Some packages include submounts having square dimensions greater than 3.5 mm used in conjunction with larger emitter chips. Materials having higher thermal conductivities are used to fabricate the submounts, providing the package with better thermal management.
US08866160B2 Light-emitting element, device, and manufacturing method including a charge injection layer having a recess for suppressing uneven luminance
A hole injection layer and a light-emitting layer are laminated between a first electrode and a second electrode of a light emitter. A bank defines an area in which the light-emitting layer is to be formed. In the area defined by the bank, a hole injection layer has a recess in an upper surface thereof. An upper peripheral edge of the recess is covered with a part of the bank.
US08866159B1 Low micropipe 100 mm silicon carbide wafer
A high quality single crystal wafer of SiC is disclosed having a diameter of at least about 100 mm and a micropipe density of less than about 25 cm−2.
US08866156B2 Silicon carbide semiconductor device and method for manufacturing same
A silicon carbide semiconductor device includes a silicon carbide substrate and a contact electrode. The silicon carbide substrate includes an n type region and a p type region that makes contact with the n type region. The contact electrode makes contact with the n type region and the p type region. The contact electrode contains Ni atoms and Si atoms. The number of the Ni atoms is not less than 87% and not more than 92% of the total number of the Ni atoms and the Si atoms. Accordingly, there can be provided a silicon carbide semiconductor device, which can achieve ohmic contact with an n type impurity region and can achieve a low contact resistance for a p type impurity region, as well as a method for manufacturing such a silicon carbide semiconductor device.
US08866155B2 Silicon carbide semiconductor device
A collector layer is made of silicon carbide having a first conductivity type. A switching element is provided on the collector layer. The switching element includes a junction gate for controlling a channel having a second conductivity type different from the first conductivity type.
US08866153B2 Functional element and manufacturing method of same
Provided is a functional element which is obtained by forming a lamination film on a substrate and then dividing the substrate and the lamination film into a desired shape. The functional element has a hexagonal substrate, a lamination film formed on a C surface of the substrate, and a plurality of divided surfaces which are exposed by dividing the substrate into quadrilaterals. At least one line of division lines in the case of dividing the substrate into quadrilaterals is perpendicular to any one of equivalent directions of [1-100], [−1010], and [01-01] of the substrate from a [0001] direction of the substrate, and the divided surfaces formed by the division lines are inclined in a direction of other divided surfaces to which at least a part thereof is opposed.
US08866149B2 Method for the reuse of gallium nitride epitaxial substrates
A method for the reuse of gallium nitride (GaN) epitaxial substrates uses band-gap-selective photoelectrochemical (PEC) etching to remove one or more epitaxial layers from bulk or free-standing GaN substrates without damaging the substrate, allowing the substrate to be reused for further growth of additional epitaxial layers. The method facilitates a significant cost reduction in device production by permitting the reuse of expensive bulk or free-standing GaN substrates.
US08866148B2 Vertical GaN power device with breakdown voltage control
A method for fabricating a vertical GaN power device includes providing a first GaN material having a first conductivity type and forming a second GaN material having a second conductivity type and coupled to the first GaN material to create a junction. The method further includes implanting ions through the second GaN material and into a first portion of the first GaN material to increase a doping concentration of the first conductivity type. The first portion of the junction is characterized by a reduced breakdown voltage relative to a breakdown voltage of a second portion of the junction.
US08866144B2 Thin film semiconductor device having silicon nitride film
An object of the present invention is to apply an insulating film of cure and high quality that is suitably applicable as gate insulating film and protective film to a technique that the insulating film is formed on the glass substrate under a temperature of strain point or lower, and to a semiconductor device realizing high efficiency and high reliability by using it. In a semiconductor device of the present invention, a gate insulating film of a field effect type transistor with channel length of from 0.35 to 2.5 μm in which a silicon nitride film is formed over a crystalline semiconductor film through a silicon oxide film, wherein the silicon nitride film contains hydrogen with the concentration of 1×1021/cm3 or less and has characteristic of an etching rate of 10 nm/min or less with respect to mixed solution containing an ammonium hydrogen fluoride (NH4HF2) of 7.13% and an ammonium fluoride (NH4F) of 15.4%.
US08866139B2 Nonvolatile semiconductor memory device
A nonvolatile semiconductor memory device of an embodiment includes: a semiconductor layer; a first insulating film formed on the semiconductor layer; a charge storage film that is formed on the first insulating film, includes C60 fullerenes, and is not less than 0.5 monolayer but is less than 1.0 monolayer; a second insulating film formed on the charge storage film; and a control electrode formed on the second insulating film.
US08866138B2 Display device and electronic device including the same
One embodiment of the present invention provides a highly reliably display device in which a high mobility is achieved in an oxide semiconductor. A first oxide component is formed over a base component. Crystal growth proceeds from a surface toward an inside of the first oxide component by a first heat treatment, so that a first oxide crystal component is formed in contact with at least part of the base component. A second oxide component is formed over the first oxide crystal component. Crystal growth is performed by a second heat treatment using the first oxide crystal component as a seed, so that a second oxide crystal component is formed. Thus, a stacked oxide material is formed. A transistor with a high mobility is formed using the stacked oxide material and a driver circuit is formed using the transistor.
US08866135B2 Anthracene derivative and organic electroluminescent element using the same
An anthracene derivative represented by the following formula (1): In the formula (1), Z is a structure represented by the following formula (2). In the formula (2), at least one pair of adjacent two substituents of R11 to R18 form a ring represented by the following formula (3) or (4):
US08866131B2 Organic light-emitting device and light source apparatus using same
An organic light-emitting device including a first substrate, a second substrate, a light drawing-out layer disposed between the first substrate and the second substrate, a transparent electrode disposed between the light drawing-out layer and the first substrate, a reflection electrode disposed between the transparent electrode and the first substrate, and a first light-emitting unit disposed between the transparent electrode and the reflection electrode. The first light-emitting unit includes a first light-emitting layer that emits a first light-emitting color. In the organic light-emitting device, relations of the equation L1≧λ2/4 and the equation L1 cos θ1=λ1 (¼+n/2) are satisfied, wherein L1 is an optical length from a light-emitting point in the first light-emitting layer to the reflection electrode, λ2 is a wavelength at the longer wavelength side, having an intensity of 1% of the maximum intensity of a light-emitting spectrum of the first light-emitting color, λ1 is a wavelength at the shorter wavelength side, having an intensity of 1% of the maximum intensity of the light-emitting spectrum of the first light-emitting color, n is an integer not less than 0, and 0 <θ1≦60.
US08866121B2 Current-limiting layer and a current-reducing layer in a memory device
A current-limiting layer and a current-reducing layer are incorporated into a resistive switching memory device to form memory arrays. The incorporated current-limiting layer reduces the occurrence of current spikes during the programming of the resistive switching memory device and the incorporated current-reducing layer minimizes the overall current levels that can flow through the resistive switching memory device. Together, the two incorporated layers help improve device performance and lifetime.
US08866118B2 Morphology control of ultra-thin MeOx layer
A nonvolatile memory device contains a resistive switching memory element with improved device switching performance and life and methods for forming the same. The nonvolatile memory device has a first layer on a substrate, a resistive switching layer on the first layer, and a second layer. The resistive switching layer is disposed between the first layer and the second layer and the resistive switching layer comprises a material having the same morphology as the top surface of the first layer. A method of forming a nonvolatile memory element in a ReRAM device includes forming a resistive switching layer on a first layer and forming a second layer, so that the resistive switching layer is disposed between the first layer and the second layer. The resistive switching layer comprises a material formed with the same morphology as the top surface of the first layer.
US08866114B2 Vision measuring device
A vision measuring device includes: an imaging device which images a workpiece; an illumination device which irradiates the workpiece with light; a position control system which controls an in-focus position of the imaging device and outputs the in-focus position as information representing a position in an in-focus axis direction; and a control device which, when the position control system controls the in-focus position, controls the frame rate of the imaging device, and controls at least one of the imaging device and the illumination device such that an amount of light to be received by the imaging device becomes substantially constant.
US08866112B2 Protective shield for protecting skin on a digit from UV radiation
A protective shield is provided for protecting the skin on a digit, such as a finger or a toe of a person, from UV radiation. The protective shield includes a longitudinal shield body that extends from a first end to a second end of the shield body, the shield body being formed of a flexible UV resistant sheet material that is sized to substantially cover the skin on the back of the digit. The first end of the shield body has a notched portion for exposing the nail of the digit and also includes a means of securing the shield body to the digit, for example a gel or an adhesive tape.
US08866110B2 Extreme ultraviolet light source
Techniques are described that enhance power from an extreme ultraviolet light source with feedback from a target material that has been modified prior to entering a target location into a spatially-extended target distribution or expanded target. The feedback from the spatially-extended target distribution provides a nonresonant optical cavity because the geometry of the path over which feedback occurs, such as the round-trip length and direction, can change in time, or the shape of the spatially-extended target distribution may not provide a smooth enough reflectance. However, it may be possible that the feedback from the spatially-extended target distribution provides a resonant and coherent optical cavity if the geometric and physical constraints noted above are overcome. In any case, the feedback can be generated using spontaneously emitted light that is produced from a non-oscillator gain medium.
US08866108B1 Microtagging motor vehicles for identification from a paint sample discovered during a criminal investigation
A vehicle microtagging system employs vehicle paint to assist in tracking vehicles used in criminal activity. Microscopic microtag particles mixed into vehicle paint contain unique alphanumeric code sequences. These particles are designed to be left behind at a crime scene, later to be recovered by law enforcement. When the microtag particles are recovered from a crime scene, law enforcement uses a simple UV light test and a magnification instrument to identify the unique alphanumeric code sequence within the microtag particles.
US08866103B2 Charged particle energy analysers and methods of operating charged particle energy analysers
A charged particle energy analyzer (10) includes inner and outer cylindrically symmetric electrodes (11,12) arranged coaxially on a longitudinal axis (z-z) of the analyzer. A position-sensitive detector (17) has a particle-receiving detection surface located off-axis, at a radial spacing from the longitudinal axis (z-z) less than the radius of the inner electrode (11). Methods of operating the charged particle energy analyzer in first and second order focussing modes are described. A position-sensitive detector (17) suitable for use in “parallel analyzers” is described (FIGS. 7 and 8).
US08866101B1 Radiation image detecting device and operating method thereof, and radiation imaging system
Binning readout reads out electric charge accumulated in pixels to signal lines in blocks of a plurality of adjoining pixel-rows. A correction image generator of a line defect corrector scales up an image size of a reference frame image RP outputted by the binning readout and corrects pixel values of the reference frame image RP, to produce a correction image RPC to be used for correction of a line defect occurring in an X-ray image XP. The scale-up is performed by applying row interpolation processing to the reference frame image RP. The correction of the pixel values is performed by multiplying the reference frame image RP after being subjected to the row interpolation processing by a correction coefficient. An adder adds the correction image RPC to the X-ray image XP, and produces an X-ray image XPC in which the line defect is corrected.
US08866098B2 Radiation detecting unit
An object is to prevent occurrence of an insensitive zone to radiation in parallel arrangement of multiple units. This radiation detecting unit 1 is provided with a PD array 5 including a plurality of PD elements 13 arrayed opposite to a scintillator 3 and output electrode pads 23 arrayed corresponding to the PD elements 13, integrated circuits 7 for processing signals from the PD elements 13, a flexible substrate 9 for mounting of the PD array 5 and integrated circuits 7, and a radiation shield plate 11 provided opposite to the PD array 5 with the flexible substrate 9 in between and formed so that ends thereof 11a are located inside the PD array 5; the output electrode pads 23 have an array pitch made shorter than that of PD elements 13; the flexible substrate 9 is folded along the ends 11a at intermediate regions A3 between mounting regions of the PD array 5 and integrated circuits 7, whereby the integrated circuits 7 are arranged on the opposite side to the PD elements 13 with the radiation shield plate 11 in between.
US08866095B2 Radiographic imaging apparatus
Provided is a radiographic imaging apparatus capable of obtaining more suitable radiological images by reducing the influence of noise generated at a current detecting section which detects current carried by applying radiation. The radiographic imaging apparatus includes a plurality of radiation detection elements two-dimensionally arranged in each region defined by a scanning line and a signal line, a switch section the state of which is switched between on and off states depending on voltage applied to the connected scanning line, a scan drive means having a gate driver that applies on voltage and off voltage to the switch section through the scanning line and a power supply circuit that supplies on voltage and off voltage to the gate driver, a current detecting section for detecting current flowing between the power supply circuit and the gate driver or current flowing through the scanning line, and a control section for detecting at least the start of applying radiation on the basis of the value of the current detected by the current detecting section.
US08866094B2 Radiation detector
There is provided a radiation detector that appropriately corrects an offset within a minute read cell without increasing area while achieving high-speed measurement at a high counting rate. A radiation detector 100 having a plurality of single-photon-counting imaging cells includes, for each imaging cell, a photodiode 3 which is applied with a reverse bias voltage and generates a current signal in response to incidence of radiation, a previous-stage DA converter d1 configured to correct an input signal based on the current signal generated by the photodiode 3, an amplifier k2 configured to amplify the signal corrected by the previous-stage DA converter d1, a subsequent-stage DA converter d2 configured to correct a charge signal amplified by the amplifier k2, a wave height discriminator 9 configured to discriminate output signals based on the signal corrected by the subsequent-stage DA converter d2, and a counter 10 configured to count the discriminated signals.
US08866093B2 Detection device manufacturing method, detection device, and detection system
In a method of manufacturing a detection device including a plurality of pixels arrayed on a substrate, the pixels each including a switch element and a conversion element including an impurity semiconductor layer disposed on an electrode, which is disposed above the switch element, which is isolated per pixel, and which is made of a transparent conductive oxide joined to the switch element, and further including an interlayer insulating layer, which is made of an organic material, which is disposed between the switch elements and the electrodes, and which covers the switch elements, the method includes insulating members each made of an inorganic material and disposed to cover the interlayer insulating layer between adjacent two of the electrodes in contact with the interlayer insulating layer, and forming an impurity semiconductor film covering the insulating members and the electrodes and becoming the impurity semiconductor layer.
US08866090B2 Radiation detecting element and radiographic imaging device
The present invention provides a radiation detecting element and a radiographic imaging device that may reliably detect radiation even when a region where radiation is irradiated is set narrowly. Namely, in the radiation detecting element and the radiographic imaging device of the present invention, plural pixels including radiographic imaging pixels and plural radiation detection pixels are disposed in a matrix in a detection region that detects radiation.
US08866088B2 Radiation image conversion panel
A radiation image conversion panel which can improve its optical output and resolution is provided. A radiation image conversion panel 1 comprises a FOP 2, a heat-resistant resin layer 3 formed on a main face 2a of the FOP 2, and a scintillator 4 formed by vapor deposition on a main face 3a of the heat-resistant layer 3 on a side opposite from the FOP 2 and made of a columnar crystal. In this radiation image conversion panel 1, the main face 3a of the heat-resistant resin layer 3 has a surface energy of at least 20 [mN/m] but less than 35 [mN/m]. This can make the crystallinity of the root part of the scintillator 4 favorable, so as to inhibit the root part of the scintillator 4 from becoming harder to transmit and easier to scatter the output light.
US08866086B2 PET scanner with emission and transmission structures in a checkerboard configuration
Apparatuses, computer-readable mediums, and methods are provided. In one embodiment, a positron emission tomography (“PET”) detector array is provided which includes a plurality of crystal elements arranged in a two-dimensional checkerboard configuration. In addition, there are empty spaces in the checkerboard configuration. In various embodiments, the empty spaces are filled with passive shielding, transmission source assemblies, biopsy instruments, surgical instruments, and/or electromagnetic sensors. In various embodiments, the crystal elements and the transmission source assemblies simultaneously perform emission/transmission acquisitions.
US08866084B2 Infrared non-destructive evaluation method and apparatus
A method of nondestructive evaluation and related system. The method includes arranging a test piece (14) having an internal passage (18) and an external surface (15) and a thermal calibrator (12) within a field of view (42) of an infrared sensor (44); generating a flow (16) of fluid characterized by a fluid temperature; exposing the test piece internal passage (18) and the thermal calibrator (12) to fluid from the flow (16); capturing infrared emission information of the test piece external surface (15) and of the thermal calibrator (12) simultaneously using the infrared sensor (44), wherein the test piece infrared emission information includes emission intensity information, and wherein the thermal calibrator infrared emission information includes a reference emission intensity associated with the fluid temperature; and normalizing the test piece emission intensity information against the reference emission intensity.
US08866079B2 Compact imaging receiver architecture
A system and method is shown for receiving microwave/millimeter-wave signals. The system and method are balanced and can be effectively implemented on a silicon substrate using single pole double throw switches.
US08866077B2 Mass spectrometer
A mass spectrometer having a multi-stage differential pumping system with an ion lens provided in a partition wall separating a second intermediate vacuum chamber and a third intermediate vacuum chamber, the incircle radii of ion guides and the size of the opening of the ion lens are determined so that the circumferential edge of the opening is located outside the circumferential surface of a virtual tubular body straightly connecting the incircle at the rear edge of the second ion guide in the front stage and the incircle at the front edge of the third ion guide in the rear stage. Although the ion lens is located in between, the radio-frequency electric field created by the second ion guide can be effectively connected to the radio-frequency electric field created by the third ion guide through the opening of the ion lens.
US08866072B2 Method and apparatus for detecting and identifying gases by means of ion mobility spectrometry
The invention relates to a method for identifying gases, which are ionized and the drift times of the positive and negative product ions through drift spaces are measured and the measured drift times are evaluated, wherein for measuring the drift times the product ions are accelerated to drift velocities by a resulting electrical field. It is provided that the positive and negative product ions move synchronously and in parallel in the same direction.The invention further relates to a device for identifying gases, which includes at least two drift tubes, wherein each of the drift tubes has at least one respective detector for detecting product ions. For this purpose, at least two drift tubes are arranged in parallel next to each other and are delimited, on one hand, by a common inlet system and, on the other hand, by at least one detector.
US08866069B1 Gamma probe health detection assembly
An improved gamma controller health detection assembly to facilitate reliable downhole measurement of naturally occurring radiation is disclosed. The gamma controller assembly includes one or more gamma sensors, a micro-controller, memory, and input/output ports among other components. The gamma sensors detect radiation and output pulses that are received by the microcontroller. The sensor data can be checked, selected, and averaged by the microcontroller, and sent uphole to another microcontroller or computer that can then further process, communicate, and display the data. The sensor data can be averaged and stored to memory or stored as independent values to memory. The gamma controller health detection assembly can be configured to run algorithms that detect if one or more gamma sensors appear to be malfunctioning or have previously malfunctioned.
US08866066B2 Lock system
Techniques are generally described for a lock system. An example lock system includes a lock with a lock module that controls a lock mechanism. The lock is configured to transmit optical signals to a key. The key reflects the optical signals back to the lock. The key is configured to encode the optical signals with a combination. The lock module is configured to determine whether the combination is valid. The lock module actuates the locking mechanism when the key is determined to be valid.
US08866062B2 Device and method for measuring light energy received by at least one photosite
A method is for measuring light energy received by a pixel including a transfer transistor, and a photodiode including a charge storage region. The method may include encapsulating the gate of the transfer transistor of the pixel in a semiconductor layer, at least one part of which includes a hydrogenated amorphous semiconductor. The method also may include grounding the charge storage region of the pixel, and determining the drift over time in the magnitude of the drain-source current of the transfer transistor.
US08866060B2 Temperature sensor and image sensor having the same
A temperature sensor includes a band gap reference (BGR) circuit, a voltage generation unit and a digital CDS circuit. The band gap reference (BGR) circuit generates a reference voltage proportional to a temperature. The voltage generation unit generates a first voltage and a second voltage based on the reference voltage, where the first voltage and the second voltage are proportional to the temperature. The digital CDS circuit generates a digital signal corresponding to the temperature by performing a digital correlated double sampling (CDS) operation on the first voltage and the second voltage. The temperature sensor is able to detect a temperature accurately.
US08866058B2 Optical transceiver and method of operation thereof
An optical transceiver comprises a substrate having a temperature control device, a light source, a light-guiding fiber, a detector, optics for collimating the light from the light source, coupling optics for focusing the light beam into the light-guiding fiber, and a beamsplitter which sends one part of the collimated light beam into a wavelength stabilization unit and another part of the collimated light beam into the coupling optics. A wavelength stabilization unit detects and compensates for wavelength drift of the light source. The optical transceiver has a superluminescent diode for its light source and may, for example, be integrated in a fiber-optic gyro.
US08866057B2 Fin deployment method and apparatus
An air vehicle that is launched from inside a launcher, includes a release mechanism for releasing fins of the vehicle from a stowed condition to a deployed condition. The release mechanism includes a pin that is located within a cavity in the fuselage of the air vehicle. Pressurized gasses initially fill the cavity in the fuselage. The launcher includes a reduced-pressure portion such as from a muzzle brake. When the air vehicle passes into the reduced-pressure portion of the launcher, the gas pressure behind the air vehicle is reduced. This causes the pressurized gas within the cavity to drive the release mechanism backwards out of the cavity. The length of the pin may be used to control the timing of the fin deployment, the delay between the initial movement of the release mechanism out of the cavity, and when the fins are released.
US08866056B2 Multi-component packaging system and apparatus
A multi-component packaging system includes a lower containing assembly, an upper containing assembly, and a cover. The lower containing assembly defines an interior cavity that is adapted to receive a first food component. The upper containing assembly defines an interior that is adapted to receive a second food component. The upper containing assembly is adapted for engagement with the lower containing assembly. The cover is engaged with at least one of the lower containing assembly and the upper containing assembly. The cover includes a passage portion that defines a plurality of apertures.
US08866054B2 Microwave energy interactive heating sheet
A microwave energy interactive heating sheet includes at least two layers of microwave energy interactive insulating material joined to one another, where each layer includes microwave energy interactive material supported on a first polymer film layer, a support layer joined to the microwave energy interactive material, and a second polymer film layer joined to the support layer in a predetermined pattern, so that a plurality of expandable cells are defined between the support layer and the second polymer film layer. The expandable cells are operative for inflating upon sufficient exposure to microwave energy.
US08866043B2 Method and apparatus for laser drilling holes with Gaussian pulses
An improved method and apparatus for drilling tapered holes in workpieces with laser pulses is presented which uses defocused laser pulses to machine the holes with specified taper and surface finish while maintaining specified exit diameters and improved system throughput. A system is described which can also drill holes with the desired taper and surface finish without requiring defocused laser pulses.
US08866042B2 Welding method and component
A process for welding a component in which a recess is filled by welding tracks is provided. The process includes providing a recess with a contour which delimits an outer upper surface of the component with respect to the recess. The welding tracks are laid such that the welding tracks also reach the surface outside a contour of the recess and that a plurality of welding layers are used in order to fill the recess until a last layer protrudes completely beyond the surface.
US08866039B1 Laser ignitability systems and methods
A laser system simulates heat flux levels of rocket motor output. A laser is mechanically associated with a platform. The laser is configured to emit an electromagnetic beam. A plurality of positions are associated with the platform. Optical elements are associated with the platform. Each optical element is positionable in a plurality of positions without changing a location of the corresponding positioner. The optical elements are arrangeable into a plurality of combinations corresponding to at least one optical path beginning at the laser and terminating at a sample. Each combination corresponds to one of a plurality of distinct permutations of operatively positioned optical elements that reducingly interact with an emitted electromagnetic beam, yielding one of many versions of the emitted electromagnetic beam that is incidented upon the sample. Each version of the emitted electromagnetic beam that is incidented upon the sample has a lower power than the emitted electromagnetic beam.
US08866037B2 Spot welding tongs including a compensation unit equipped with a curved connector element
The invention relates to spot welding tongs with tong compensation, including a tong base body (4), two tong arms (6, 7) and a compensation unit (17) movably connecting one of the tong arms (6, 7) with the tong base body (4) and designed to convert a rotational movement into a linear movement, wherein the compensation unit (17) is composed of a drive unit (18) and a connector element (19), and the connector element (19) is eccentrically and movably fastened to an eccentric disc (23) fastened to the drive unit (18). In order to provide such spot welding tongs (1) with a compensation unit, which converts the rational movement into a linear movement, the connector element (19) is designed to be curved in an end region.
US08866036B2 Welding torch and adapter kit
According to the present invention, an adapter kit is provided in which a welding torch having a single nozzle structure is switched to a welding torch having a double nozzle structure. In an adapter kit (20A) which is installed in a switchable manner in a welding torch (1A) having a single nozzle structure, the present invention includes an attachment (7A) which is mounted to the torch body (5) in a state where the torch nozzle (inner nozzle) (6A) is inserted into the attachment after the gasket is removed and in which a flow channel that supplies a second shielding gas is provided, and an outer nozzle (8A) that is mounted to the attachment (7A) surrounding the periphery of the torch nozzle (6A) and discharges a second shielding gas.
US08866034B2 Arc runner with integrated current path that develops a magnetic field to boost arc movement towards splitter plates
A circuit interrupter for cooling and quenching an electrical arc having a housing with a first contact and a second contact movable with respect to the first contact. An arc splitter is located in an arcing chamber, and an arc runner is located near the second contact. The arc runner has an arc strap facing toward the first contact, a first wall shaped as a rectangular spiral perpendicularly extending from the arc strap, a second wall shaped as a rectangular spiral perpendicularly extending from to the arc strap and opposite the first wall. The arc runner generates a magnetic force on the arc forcing the arc toward the arc splitter.
US08866033B2 Key module and electronic device including the same
An electronic device includes a case and a key module. The key module is mounted on a supporting surface of a housing of the case and includes: a touch pad, a circuit board, a press switch and a transmission member. The press switch is coupled electrically to the circuit board and is disposed at a position corresponding to the middle of the touch pad in a lengthwise direction. The transmission member is mounted between the circuit board and the supporting surface, and includes two levers and a press member disposed between the levers and abutting against the press switch. A corresponding electrical signal can be produced by abutment of the press member against the press switch linked by the transmission member.
US08866032B2 Electrical switch for nautical equipment
The disclosure concerns an electrical switch for nautical equipment. The switch comprises electric actuation means, which in turn comprise at least one control button, able to be connected to an external electric circuit, and a housing of such electric actuation means. Advantageously, the switch also comprises a covering element that is moveable with respect to the housing between a first position, at which the button can be directly activated by the user by just inserting a finger into a suitable recess, and a second position, at which the covering element prevents direct access to the button and is itself moveable by the user in the direction towards the button for its activation. When the covering element is in the second position, the activation of the button can be obtained by pressing the covering element with a foot or with a hand.
US08866028B2 Combination weighing device that divides material treating units into two sections with separate data receiving and delivering communication converters for each section
A combination weighing device and an operating method thereof are disclosed. The device comprises N material treating units, a mainboard, chutes (10, 11, 16, 17) and discharging hoppers (12, 13, 14), wherein the material treating units are used for receiving materials, outputting the weight value of materials and discharging materials according to the discharging control signal from the mainboard; the mainboard is used for selecting materials by combinatorial calculation based on the present-period weight value during every period and outputting the discharging control signal to weighing hoppers (7); the chutes (10, 11, 16, 17) are used for collecting the materials through a discharging route, discharging the materials to the discharging hoppers (12, 13, 14), after a discharging route is determined; the discharging hoppers (12, 13, 14) are used to separately collect materials discharged from the chutes (10, 11, 16, 17) during the same weighing period and send the materials to a packing machine; each material treating unit comprises a linear vibrator (5), a feed hopper (6), a weighing hopper (7), a weighing sensor used to weigh the materials in the weighing hopper (7), a processor and a A/D converter which is connected with the weighing sensor and the processor, N material treating units are connected with the mainboard signal together by two data receiving and delivering communication converters of the mainboard.
US08866025B2 Multilayer wiring board
A multilayer wiring board including a build-up layer comprising a conductor layer and a resin insulation layer that are alternately layered, conductive pads formed on a surface of a resin insulation layer so as to project from the surface, and a solder layer formed over an upper surface of each of the conductive pads is provided. The upper surface of the conductive pads may have a recess, and the entire surface of the solder layer may be situated at an elevated position with respect to an outer periphery portion of the upper surface.
US08866020B2 Method for manufacturing printed circuit board, method for manufacturing printed circuit board assembly sheet, printed circuit board, and printed circuit board assembly sheet
Base insulating layers are formed on a support substrate having a conductive property. The support substrate is etched, to form support substrate board and a plurality of conductive portions in a suspension board. The holding piece and the conductive portions constitute a shape determination unit. The conductive portions have first to fifth conductive portions. The third and fourth conductive portions are spaced apart from each other, and the fifth conductive portion is formed between the third and fourth conductive portions. The first and second conductive portions are respectively formed integrally with one end and the other end of the fifth conductive portion. It is determined whether the first and second conductive portions in the shape determination unit are connected electrically to each other. And it is determined whether the first and third conductive portions are connected electrically to each other.
US08866019B2 Electric wire, coil, device for designing electric wire, and electric motor
An electric wire includes a conductive portion 11 made of a material having a volume resistivity higher than that of copper, wherein the volume resistivity of the conductive portion is specified so that, in a frequency range in which the electric wire is used, a ratio of AC resistance of the conductive portion 11 to AC resistance of reference copper wire is less than 1.
US08866018B2 Passive electrical devices and methods of fabricating passive electrical devices
A thin laminate passive electrical device, such as, a capacitor, and a method of fabricating a thin laminate passive electrical device are provided. The passive electrical device includes two conductors, for example, copper foil conductors, separated by a dielectric having a first layer of a first material having a softening point temperature greater than a first temperature and a first layer of a second material having a softening point temperature less than the first temperature. The first temperature may be at least 150 degrees C. or higher. By providing a first layer having a higher softening point material, shorting across the conductors, that can be promoted by the fabrication process, is prevented. Methods of fabricating passive electrical devices are also disclosed.
US08866015B2 Power cable with conducting outer material
A power cable comprises at least one insulated cable core having an electric conductor, a screen and an outer insulating sheath surrounding the core/cores, and an outer conducting material attached to the exterior of the outer sheath. The outer conducting material includes at least one band attached to the outer sheath extending along the full length of the cable and having a width (W) extending over only a part of an outer periphery of the cable. At least one groove extends along the cable outer sheath and the band/bands of conducting material are received in the groove/grooves, or at least one rib extends along the cable outer sheath and the band/bands of conducting material are attached to an outer surface of said rib/ribs; or at least one band of the outer conducting material is adhered to the outer sheath and requires a stripping force.
US08866014B2 Dead front cable terminal with isolated shield
Provided is a dead front cable terminal comprising a cable assembly and connector device in which the cable insulation shield and cable metallic ground of the cable assembly are electrically isolated from the portion of the outer semi-conductive layer of the connecting device that forms part of a chamber in which at least a portion of the cable assembly is located. The terminal is suitable for cross bonding.
US08866012B2 Sensor lead sealing and strain relief
A sensor system includes a wiring harness including at least one wire, a grommet, a nugget, a sensor, and a harness sleeve, wherein the grommet includes at least one passageway configured to receive the wire and the nugget includes at least one terminal molded into the nugget and coupled to the wire. A mineral insulated cable may be coupled to the sensor and to the terminal and the harness sleeve may define at least one cavity configured to receive the nugget and at least a portion of the grommet. The harness sleeve may be coupled to the mineral insulated cable and may include a first crimp coupling the harness sleeve to the grommet. The harness sleeve may also include a second crimp coupling the harness sleeve to the nugget.
US08866011B2 Electronic device and connection mechanism thereof
A connection mechanism is provided. The connection mechanism includes a first fixing member, a fixer, an elastic element, a second fixing member and a connection element. The first fixing member includes a first side and second side, wherein the first side is opposite to the second side. The fixer passes through the first fixing member and is pivotable relative to the first fixing member along the first direction, wherein the fixer has a head portion and an end portion. The head portion is located on the first side and has an outer surface, and the second portion protrudes from the second side. The elastic element is disposed on the first side of the first fixing member and is abutting the outer surface, to prevent the fixer from rotating along a direction opposite the first direction. The connection element is disposed on the second fixing member and has a hollow structure.
US08866010B2 Differential signal transmission cable and multi-core cable
A differential signal transmission cable includes a pair of center conductors for transmitting a differential signal, an insulator covering peripheries of the center conductors, a shield tape longitudinally wrapped around the insulator, an insulating tape including an adhesive surface and spirally wrapped around the shield tape while the adhesive surface faces inside, and a non-adhesive tape provided between the shield tape and the insulating tape along a longitudinal direction, and non-adhesively covering a part of an outer periphery of the shield tape in a circumferential direction.
US08866007B2 Plasmonic photovoltaics
A surface plasmon polariton photovoltaic absorber. A plasmonic photovoltaic device is provided that has a periodic subwavelength aperture array, for example a thin metal film coated with an array of semiconductor quantum dots. The plasmonic photovoltaic device generates an electrical potential when illuminated by electromagnetic radiation. In some embodiments, the absorber can contain both quantum dots of semiconductors and metal nanoparticles.
US08866005B2 InGaP heterojunction barrier solar cells
A new solar cell structure called a heterojunction barrier solar cell is described. As with previously reported quantum-well and quantum-dot solar cell structures, a layer of narrow band-gap material, such as GaAs or indium-rich InGaP, is inserted into the depletion region of a wide band-gap PN junction. Rather than being thin, however, the layer of narrow band-gap material is about 400-430 nm wide and forms a single, ultrawide well in the depletion region. Thin (e.g., 20-50 nm), wide band-gap InGaP barrier layers in the depletion region reduce the diode dark current. Engineering the electric field and barrier profile of the absorber layer, barrier layer, and p-type layer of the PN junction maximizes photogenerated carrier escape. This new twist on nanostructured solar cell design allows the separate optimization of current and voltage to maximize conversion efficiency.
US08866003B2 Solar cell employing an enhanced free hole density p-doped material and methods for forming the same
A p-doped semiconductor layer of a photovoltaic device is formed employing an inert gas within a carrier gas. The presence of the inert gas within the carrier gas increases free hole density within the p-doped semiconductor layer. This decreases the Schottky barrier at an interface with a transparent conductive material layer, thereby significantly reducing the series resistance of the photovoltaic device. The reduction of the series resistance increases the open-circuit voltage, the fill factor, and the efficiency of the photovoltaic device. This effect is more prominent if the p-doped semiconductor layer is also doped with carbon, and has a band gap greater than 1.85V. The p-doped semiconductor material of the p-doped semiconductor layer can be hydrogenated if the carrier gas includes a mix of H2 and the inert gas.
US08866001B1 Luminescent solar concentrator
A stacked luminescent solar concentrator includes two separate absorption/emission cells, each having a layer of luminophore-type material, wherein a top layer is a high band gap layer comprised of quantum dots in polymer, wherein the quantum dots are engineered so as to absorb a significant percentage of photons above bandgap. The bottom layer is a lower band gap layer comprised of quantum dots in polymer, wherein the quantum dots in the second layer are engineered so as to absorb photons not absorbed in the top layer, thus increasing total percentage of absorbed photons. Photovoltaic cells are located below the layers at the bottom of the cells or at the edges of the cells. The sides and lower surfaces of the cells may include reflective surfaces as discussed further herein. Reflection losses from the top surface thereof may be minimized using a broadband anti-reflective coating (AR) on the surface.
US08865998B2 Photovoltaic electrochromic device
A photovoltaic electrochromic device and a method of manufacturing the same are provided. According to the method, at least one thin-film solar cell is formed on a transparent substrate, wherein the thin-film solar cell at least includes an anode, a photoelectric conversion layer, and a cathode, and a portion of a surface of the anode is exposed from the thin film solar cell. An electrochromic thin film is then deposited on at least one surface of the cathode and the exposed surface of the anode. Thereafter, an electrolyte layer is formed on a surface of the thin-film solar cell to cover the electrochromic thin film. The anode and the cathode of the thin-film solar cell also serve as the anode and the cathode of the photovoltaic electrochromic device.
US08865995B2 Methods for high figure-of-merit in nanostructured thermoelectric materials
Thermoelectric materials with high figures of merit, ZT values, are disclosed. In many instances, such materials include nano-sized domains (e.g., nanocrystalline), which are hypothesized to help increase the ZT value of the material (e.g., by increasing phonon scattering due to interfaces at grain boundaries or grain/inclusion boundaries). The ZT value of such materials can be greater than about 1, 1.2, 1.4, 1.5, 1.8, 2 and even higher. Such materials can be manufactured from a thermoelectric starting material by generating nanoparticles therefrom, or mechanically alloyed nanoparticles from elements which can be subsequently consolidated (e.g., via direct current induced hot press) into a new bulk material. Non-limiting examples of starting materials include bismuth, lead, and/or silicon-based materials, which can be alloyed, elemental, and/or doped. Various compositions and methods relating to aspects of nanostructured thermoelectric materials (e.g., modulation doping) are further disclosed.
US08865994B2 Electronic music system
An electronic music system includes a computer which performs a sequencing function and a remote controller. The remote controller is provided with a start operator and a selection operator. In response to an instruction made by the start operator of the remote controller, the computer or the remote controller adds a new track on a sequencer configured on the computer. The computer or the remote controller then offers options of available different types of tone generators used for the track, and in accordance with a selection made by the selection operator in a state where the available different types of tone generators have been offered, assigns the selected type of tone generator to the track.
US08865993B2 Musical composition processing system for processing musical composition for energy level and related methods
A musical composition processing system may include a storage device for storing reference musical compositions, an energy level characteristic value for each reference musical composition, and an attribute profile for each reference musical composition, and a computing device in communication with the storage device and for processing an input musical composition. The processing of the input musical composition may include determining an attribute profile for the input musical composition based upon transient and ambient sounds in the input musical composition, and determining an energy level characteristic data value for the input musical composition by correlating the attribute profile of the input musical composition to the respective attribute profiles and the energy level characteristic data values of the reference musical compositions.
US08865989B1 Kinetic measurement of piano key mechanisms for inertial properties and keystroke characteristics
Important new descriptors (Down Force Slope and Up Force Slope), which more fully and meaningfully characterize the continuous Down Force and Up Force are revealed. Similar descriptors are also created to more fully characterize the Balance Force and Frictional Force curves. The invention also discloses various methods and means for accurately testing, measuring and determining other parameters (including the position of the at-rest key, key sluggishness, and others characterizing the “let-off” event) in an accurate and efficient manner. Methods of quantifying and measuring the actual inertia of a key action—in a non-invasive manner—are also disclosed, with several inertial parameters being defined. Methods for quantifying and measuring the actual inertia of the major individual components of a key action are also detailed, along with parameters and methods for expressing their contribution “at the key”. All of the various measurement methods of the current invention are performed in a “controlled, kinetic and continuous” manner.
US08865987B2 Percussion instrument
A percussion instrument includes at least one pad and a support frame supporting the pad. The support frame includes a central vertical frame, a left vertical frame located in a left rear direction of the central vertical frame when viewed from the player side, a right vertical frame located in a right rear direction of the central vertical frame when viewed from the player side, a left transverse frame extending between the central vertical frame and the left vertical frame and connecting the central vertical frame with the left vertical frame, and a right transverse frame extending between the central vertical frame and the right vertical frame and connecting the central vertical frame with the right vertical frame. The at least one pad is connected with the central vertical frame.
US08865986B1 Jazz flat ride and methods of making the same
A jazz ride is a flat plate from a mounting hole to a peripheral edge wherein at least one segment is provided with a plurality of narrow annular slots separated by annular webs. The jazz ride may be a circular flat plate provided with multiple segments of different angular length.
US08865984B2 Plants and seeds of common wheat cultivar BZ6W07-458
A wheat cultivar, designated BZ6W07-458, is disclosed. The invention relates to the seeds, plants, and hybrids of wheat cultivar BZ6W07-458, and to methods for producing a wheat plant produced by crossing plants from wheat cultivar BZ6W07-458 with themselves or with plants from another wheat variety. The invention also relates to methods for producing a wheat plant containing in its genetic material one or more transgenes and to the transgenic wheat plants and plant parts produced by those methods. The invention also relates to wheat varieties or breeding varieties and plant parts derived from wheat cultivar BZ6W07-458, to methods for producing other wheat varieties, lines or plant parts derived from wheat cultivar BZ6W07-458, and to the wheat plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid wheat seeds and plants produced by crossing wheat cultivar BZ6W07-458 with another wheat cultivar.
US08865983B2 Plants and seeds of common wheat cultivar BZ6W07-427
A wheat cultivar, designated BZ6W07-427, is disclosed. The invention relates to the seeds, plants, and hybrids of wheat cultivar BZ6W07-427, and to methods for producing a wheat plant produced by crossing plants from wheat cultivar BZ6W07-427 with themselves or with plants from another wheat variety. The invention also relates to methods for producing a wheat plant containing in its genetic material one or more transgenes and to the transgenic wheat plants and plant parts produced by those methods. The invention also relates to wheat varieties or breeding varieties and plant parts derived from wheat cultivar BZ6W07-427, to methods for producing other wheat varieties, lines or plant parts derived from wheat cultivar BZ6W07-427, and to the wheat plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid wheat seeds and plants produced by crossing wheat cultivar BZ6W07-427 with another wheat cultivar.
US08865978B1 Maize variety hybrid X7H292
A novel maize variety designated X7H292 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing maize variety X7H292 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X7H292 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X7H292, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X7H292. This invention further relates to methods for producing maize varieties derived from maize variety X7H292.
US08865976B2 Melon hybrid SV1047MF and parents thereof
The invention provides seed and plants of melon hybrid SV1047MF and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of melon hybrid SV1047MF and the parent lines thereof, and to methods for producing a melon plant produced by crossing such plants with themselves or with another melon plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
US08865974B1 Canola line NS6162
A novel canola variety designated NS6162 and seed, plants and plant parts thereof. Methods for producing a canola plant that comprise crossing canola variety NS6162 with another canola plant. Methods for producing a canola plant containing in its genetic material one or more traits introgressed into NS6162 through backcross conversion and/or transformation, and to the canola seed, plant and plant part produced thereby. Hybrid canola seed, plant or plant part produced by crossing the canola variety NS6162 or a locus conversion of NS6162 with another canola variety.
US08865971B2 Methods of transforming somatic cells of maize haploid embryos
Methods for producing homozygous plants, seeds, and plant cells are provided. The methods comprise transforming a somatic cell of a maize haploid embryo with a polynucleotide of interest and treating the transformed cell with a chromosome doubling agent. One or more growth stimulation proteins, such as, for example, RepA or Lec1, may also be provided.
US08865962B2 Multipurpose medical wrap
The multipurpose medical wrap serves as a dressing, covering, splint holder, and/or various other emergency medical uses. The wrap includes a central pad having two layers of material defining a plurality of internal pockets therebetween for the insertion of various treatment packs and/or splints therein. The pad includes a relatively soft sheet to protect the area to which it is applied, and a relatively thin, non-insulating sheet that allows the pad to be reversed for use in applying hot and cold packs and the like. An end flap extends from each end of the central pad for additional protection and/or treatment. A plurality of laterally overlapping straps extends from each side of the central pad. Corresponding opposite straps are interwoven to secure the wrap to the body, some straps being used to form a sling and/or torso securing swath when the wrap is used as an arm treatment.
US08865961B2 Methods for dissolution and instant neutralization of solid nitrocellulose propellants and plasticized military munitions
Nitrocellulose propellants and plasticized military munitions, equipment, or contaminated soil are placed in a suitable container. A first option consists of adding a strong base to plasticized munitions in a container or militarization/demilitarization equipment or soil containing plasticized munitions or nitrocellulose propellant; adding an organic solvent; and then adding water to mixture. Alternatively, a second option consists of adding organic co-solvent to plasticized munitions in a container or soil containing plasticized munitions or solid nitrocellulose propellant. A strong base is added to mixture and allowed to react. When the reaction stops or is completed, a sulfur based bulk reductant is added to degrade all nitro and amino compounds. The organic solvent is evaporated and recovered for reuse and water is added to the container to make up for the evaporated organic solvent. If pH is higher than 8.5, a suitable acid is added to drop the pH to near neutral.
US08865960B2 Startup procedures for ionic liquid catalyzed hydrocarbon conversion processes
Methods for starting and operating ionic liquid catalyzed hydrocarbon conversion processes and systems to provide maximum process efficiency, system reliability and equipment longevity may include: purging air and free water from at least a portion of the system; introducing at least one reactant into the at least a portion of the system; and re-circulating the at least one reactant through the at least a portion of the system, via at least one feed dryer unit, until the at least one reactant exiting the at least a portion of the system has a water content at or below a threshold value, prior to the introduction of an ionic liquid catalyst and/or additional reactant(s) and feeds into the system.
US08865959B2 Process for synthetic lubricant production
A process for the preparation of oligomeric poly alpha-olefins includes oligomerizing low molecular weight PAO oligomer in the presence of a Lewis acid catalyst such as promoted aluminum trichloride or boron trifluoride under oligomerization conditions. The low molecular weight PAO oligomers used as a feed or feed component of the present process are the light olefinic by-product fractions including the dimers and light fractions from the metallocene-catalyzed PAO oligomerization process which are characterized by a molecular weight of 150 to 600 and a terminal olefin (vinylidene) content of at least 25%.
US08865957B2 Method for producing alpha-methyl styrene from cumene
A method for controlling the production of heavy compounds in the production of alpha-methyl styrene is provided. In one embodiment, the method includes providing a first composition to a distillation column, said first composition comprising acetone, phenol, cumene and alpha-methyl styrene; refining the first composition in the distillation column to produce a second composition comprising at least 1 wt. % alpha-methyl styrene and at least one organic acid, wherein the second composition includes a higher weight percentage of alpha-methyl styrene than the first composition; and adding an amine to the second composition.
US08865954B2 Production of diesel fuel from biorenewable feedstocks with selective separation of converted oxygen
A process has been developed for producing diesel boiling range fuel from renewable feedstocks such as fats and oils from plants and animals where the process provides for sulfur-component management. The process involves catalytically treating a renewable feedstock by hydrogenating and deoxygenating to provide a hydrocarbon fraction useful as a diesel boiling range fuel. A selective separation such as a hot high pressure hydrogen stripper may be used to remove at least the carbon oxides from the first zone effluent and provide a liquid recycle stream at pressure and temperature. A vapor stream is separated from the net process effluent and at least carbon dioxide is removed using at least one selective or flexible amine absorber. The resulting hydrogen-rich stream is recycled to the reaction zone.
US08865953B2 Production of diesel fuel from biorenewable feedstocks with selective separation of converted oxygen
A process has been developed for producing diesel boiling range fuel from renewable feedstocks such as plant and animal fats and oils, the process providing for sulfur management. The process involves catalytically treating a renewable feedstock by hydrogenating and deoxygenating to provide a hydrocarbon fraction useful as a diesel boiling range fuel. The hydrocarbon fraction is isomerized to improve cold flow properties. A selective separation such as a hot high pressure hydrogen stripper is used to remove at least the carbon oxides from the first zone effluent before entering the isomerization zone, and to provide liquid recycle to the treating zone at pressure and temperature. A vapor stream is separated from the isomerization effluent and at least carbon dioxide is removed using at least one selective or flexible amine solution absorber. The resulting hydrogen-rich stream is recycled to the deoxygenation reaction zone.
US08865947B2 Process for producing fluorinated alcohols
The present invention is directed to a process for preparation of fluorinated alcohols of Formula (I) RfCH2CH2OH  (I) by contacting a fluorinated iodide with an alkyl vinyl ether in the presence of an initiator and a base to generate an intermediate hemi-acetal or aldehyde or a mixture thereof, followed by hydrogenation of the hemi-acetal of Formula (II) RfCH2CH(OCxH2x+1)m(OH)p  (II) or aldehyde of Formula (III) RfCH2CHO  (III) or a mixture thereof, to yield a compound of Formula (I).
US08865945B2 Process for the preparation of polyols
The present invention provides polyols which can be obtained by a simple process. These polyols, unless explicitly specified, are to be understood to encompass both polyether polyols and polyether ester polyols. The invention further provides the simple process for the production of the polyols, and also, the production of polyurethanes comprising reacting a polyol according to the invention with a polyisocyanate.
US08865941B2 Process for the preparation of alkyldiamines
Provided is a process for preparing alkyl diamine compounds in high purity. The process utilizes an alkyl amine compound during the reduction of a nitroamine, resulting in reduction of the concentration of undesired byproducts.
US08865940B2 Process for preparing 1,6-hexanediol
Disclosed are processes for preparing 1,6-hexanediol and synthetic intermediates useful in the production of 1,6-hexanediol from renewable biosources. In one embodiment, a process comprises contacting levoglucosenone with hydrogen in the presence of a first hydrogenation catalyst at a first temperature to form product mixture (I); and heating product mixture (I) in the presence of hydrogen and a second hydrogenation catalyst at a second temperature to form product mixture (II) which comprises 1,6-hexanediol. In one embodiment, the 1,6-hexanediol is converted to 1,6-diaminohexane.
US08865938B2 Method for producing bis(aminomethyl)cyclohexanes
A method for producing bis(aminomethyl)cyclohexanes includes a nuclear hydrogenation step of producing hydrogenated phthalic acids or phthalic acid derivatives by nuclear hydrogenation of phthalic acids or phthalic acid derivatives of at least one selected from the group consisting of phthalic acids, phthalic acid esters, and phthalic acid amides; a cyanation step of treating the hydrogenated phthalic acids or phthalic acid derivatives obtained in the nuclear hydrogenation step with ammonia, thereby producing dicyanocyclohexanes; and an aminomethylation step of treating the dicyanocyclohexanes obtained in the cyanation step with hydrogen, thereby producing bis(aminomethyl)cyclohexanes. In the cyanation step, metal oxide is used as a catalyst, and the obtained dicyanocyclohexanes have a metal content of 3000 ppm or less.
US08865937B2 Crystalline forms of (1S,2R)-2-(amino methyl)-N,N-diethyl-1-phenyl cyclopropane carboxamide
The present invention relates to novel crystalline forms of (1S,2R)-2-(amino methyl)-N,N-diethyl-1-phenyl cyclopropane carboxamide. Processes for the preparation of this form, compositions containing the form, and methods of use thereof are also described.
US08865935B2 Purification methods for betulonic acid and Boc-lysinated betulonic acid, and organic synthesis of betulonic acid amides with piperazine derivatives
The present invention provides a method of purifying betulonic acid contained the reaction product of organic synthesis of a Jones oxidation reagent and betulin extracted from the bark of a birch, a method of preparing a piperazine betulonic acid amide derivative, which is used as a chemical having an antibacterial function, using the high-purity betulonic acid obtained by the purification method and a derivative prepared by this method, a method of purifying a Boc-lysinated betulonic acid monomer ester contained in the reaction product of organic synthesis of lysine and the high-purity betulonic acid (starting material) obtained by the purification method, and a method of purifying Boc-lysinated betulonic acid contained in the reaction product of hydrolysis of the high-purity Boc-lysinated betulonic acid monomer ester.
US08865933B2 Method for obtaining optically pure amino acids
This invention relates to a method for obtaining optically pure amino acids, including optical resolution and optical conversion. This method significantly shortens the time taken for optical transformation, and enables the repeated use of an organic solution containing a enantioselective receptor, to thereby obtain optically pure amino acids in a simple and remarkably efficient manner, and to enable the very economical mass production of optically pure amino acids.
US08865931B2 Transesterification process using mixed salt acetylacetonates catalysts
This invention is directed to a process for the production of a variety of esters, particularly acrylate and methacrylate-based esters, by a transesterification reaction. This objective is achieved by reaction of an ester of a carboxylic or a carbonic acid, in particular of a saturated or unsaturated, typically, a 3 to 4 carbon atom carboxylic acid; with an alcohol in the presence of a catalyst comprising the combination of a metal 1,3-dicarbonyl complex (pref. Zn or Fe acetylacetonate) and a salt, in particular an inorganic salt, pref. ZnCl2, LiCI, NaCI, NH4CI or Lil. These catalysts are prepared from readily available starting materials within the reaction medium without the need for isolation (in-situ preparation).
US08865927B2 Method for preparing a diorganodihalosilane
A method of preparing a diorganodihalosilane, the method comprising the following separate and consecutive steps: (a) treating a metal catalyst comprising a metal selected from the groups consisting of i) gold, ii) gold and copper, iii) gold, copper and magnesium, iv) copper, rhodium and gold, v) copper, rhodium, and rhenium, vi) rhenium and palladium, vii) copper, and viii) copper and magnesium with a mixture comprising hydrogen gas and an organotrihalosilane at a temperature from 500 to 1400° C. to form a silicon-containing metal intermediate; and (b) reacting the silicon-containing metal intermediate with an organohalide according to the formula RX, wherein R is C1-C10 hydrocarbyl and X is halo, at a temperature from 100 to 600° C. to form a diorganodihalosilane and a depleted silicon-containing metal intermediate.
US08865915B2 Process for the preparation of the L-arginine salt of perindopril
Process for the preparation of the compound of formula (I):
US08865914B2 Fluorescent probes for detection of copper
The invention provides fluorescent sensors for the selective detection of a metal such as copper. The sensors may be considered to be derivatives of cyanine, fluorescein, rhodamine, rhodol, Tokyo green, or BODIPY. The sensors find particular use in detecting copper in cells and living animals.
US08865911B2 Compounds and their use as BACE inhibitors
The present invention relates to compounds of formula (I) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of Aβ-related pathologies such as Down's syndrome, β-amyloid angiopathy such as but not limited to cerebral amyloid angiopathy or hereditary cerebral hemorrhage, disorders associated with cognitive impairment such as but not limited to MCI (“mild cognitive impairment”), Alzheimer's disease, memory loss, attention deficit symptoms associated with Alzheimer's disease, neurodegeneration associated with diseases such as Alzheimer's disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration.
US08865906B2 Process for the preparation of a compound useful as an inhibitor of TAFIa
The present invention relates to a process for the preparation of a compound of the formula I, which comprises reacting a compound of the formula IV with an oxalic acid diester and to novel intermediate compounds used therein.
US08865904B2 Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use
Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA.
US08865899B2 Chemical process for the synthesis of 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline
The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline (ZD6474)
US08865897B2 Crystal modifications-3-(1H-indol-3-yl)-4- [4-methyl-piperazin-1-yl)-quinazolin-4-yl] -pyrrole-2, 5-D ione
The invention relates to a new crystalline form of the acetate salt of which may be used, for example, for prevention or treatment of transplant rejection.
US08865896B2 Method for preparing adenine compound
A method for producing adenine compound (1): wherein m and n are independently an integer of 2 to 5, R1 is C1-6 alkyl group, R2 and R3 are the same or different, and hydrogen atom, or C1-6 alkyl group, or R2 and R3 are combined with an adjacent nitrogen atom to form pyrrolidine, morpholine, piperidine, piperazine, etc., and R4 is C1-3 alkyl group, which comprises a step of reacting compound (2): and compound (3): in the presence of a boron-containing reducing agent.
US08865893B2 Method for preparing 2-morpholinoisobornane-10-thiol and intermediates formed therein
A method for preparing 2-morpholinoisobornane-10-thiol is disclosed, which has simplified steps and avoids the use of Na metal. Accordingly, it is advantageous to apply the method in a mass production.
US08865890B2 Redox-active structures and devices utilizing the same
A device is presented having reversibly changeable and optically readable optical properties. The device comprises a substrate having an electrically conductive surface and carrying a redox-active layer structure. The redox-active layer structure may be a monolayer or a multi-layer structure and is configured to have at least one predetermined electronic property including at least one of electrodensity and oxidation state. The electronic property of the layer structure defines an optical property of the structure thereby determining an optical response of the structure to certain incident light. This at least one electronic property is changeable by subjecting the redox-active layer structure to an electric field or to a redox-active material. The device thus enables effecting a change in said electronic property that results in a detectable change in the optical response of the layer structure.
US08865882B2 Methods for detecting human papilloma virus-associated cancers
The present invention provides probes and methods of use thereof in the diagnosis and/or prognosis of certain types of cancers, particularly human papillomavirus (HPV)-associated cancers. The probes are designed for hybridization with genomic material in a manner indicative of one or more aberrations in the genetic material present in the test sample. The identified aberrations are biomarkers of HPV-associated cancer. The methods of the invention comprise contacting a sample to one or more probes, allowing any genetic material in the sample to hybridize to the genomic regions provided in the probes, analyzing the hybridizations, and analyzing the hybridizations to identify detected aberrations as biomarkers indicative of HPV-associated cancer progression.
US08865879B2 Chitosan beads and filler comprising such beads
The present invention pertains to chitosan beads consisting of chitosan cross-linked with citrate ions. The present invention furthermore pertains to a filler comprising such chitosan-citrate beads. In one embodiment of the instant invention the filler is a dermal filler. In one further embodiment of the present invention the dermal filler is for the treatment of wrinkles and/or folds. In another embodiment of the instant invention the filler is for use in the treatment of a medical condition. The filler provided in the present invention may further comprise one or more active pharmaceutical ingredients. Further, the present invention pertains to a process for preparing the filler as claimed herein.
US08865876B2 Engineered lectin oligomers with antiviral activity
Engineered lectins and methods of using such reagents for both preventing and treating a broad array of viral infections are provided. The lectins of the invention are engineered in two ways, first through the enhancement of the natural mode of action of lectins against viruses through linked multimerization, and second through the creation of a new class of reagents, hereinafter referred to as a “lectibody” or “lectibodies”, that engage host immune function in addition to simply binding glycosylated viral proteins via the combination of a lectin and the Fc region of an antibody in order to drive Fc-mediated effector functions including ADCC (antibody-dependent cell-mediated cytotoxicity), increased half-life, complement-dependent cytotoxicity (CDC), and antibody-dependent cell-mediated phagocytosis (ADCP) in response to a lectin-mediated carbohydrate-binding event.
US08865875B2 Site-specific attachment of drugs or other agents to engineered antibodies with C-terminal extensions
The present invention provides antibodies (e.g., IgG antibodies) having C-terminal cysteine-containing extensions that facilitate antibody conjugation to a partner molecule (e.g. a drug, toxin, marker molecule, protein, radioisotope, or other therapeutic agent). Methods of making, screening and selecting the antibodies of the invention are provided.
US08865873B2 Internalizing human monoclonal antibodies targeting prostate cancer cells in situ
This invention provides a method that allows selection of antibodies against cells (e.g., tumor cells) in situ using laser capture microdissection. By restricting antibody selection to binders of internalizing epitopes, a panel of phage antibodies was generated that targets clinically represented prostate cancer antigens.
US08865869B2 Collagen and fibrin microthreads in a discrete thread model of in vitro ACL scaffold regeneration
Compositions that include fibrin microthreads are provided. The compositions can include one or more therapeutic agents including cytokines and interleukins, extracellular matrix proteins and/or biologically active fragments thereof (e.g., RGD-containing peptides), hormones, vitamins, nucleic acids, chemotherapeutics, antibiotics, and cells. Also provided are methods of making compositions that include fibrin microthreads. Also provided are methods for using the compositions to repair or ameliorate damaged or defective organs or tissues.
US08865867B2 Lectins and uses thereof
The present invention relates to chemical compounds, methods for their discovery, and their therapeutic and research use. In particular, the present invention provides antiviral and antimicrobial lectin compounds (BanLec) isolated from bananas. These compounds have low mitogenicity and pro-inflammatory activity while maintaining anti-HIV-1 activity.
US08865865B2 N-terminally modified tetrapeptide derivatives having a C-terminal arginine mimetic
The invention refers to multibasic, N-terminally modified tetrapeptide mimetics with a C-terminal P1-arginine mimetic, methods for their production and use for therapy and prophylaxis of diseases, caused by bacterial pathogens or viruses, as well as for therapy and prophylaxis of diabetes, arteriosclerosis, cancer, Alzheimer's or the onset of obesity, as well as the use of these compounds as inhibitors of the proprotein convertases which cleave behind basic P1 residues, especially for inhibition of the protease furin.
US08865863B2 MCR dendrimers
The invention relates to a method for producing peptoidic, peptidic and chimeric peptidic-peptoidic dendrimers by multiple iterative multi-component reactions (MCR), in particular Ugi or Passerini multi-component reactions, to compounds produced in this way and to the use thereof.
US08865858B2 Process for producing a composite material
The present invention relates to a process for producing a composite material composed of a) at least one oxidic phase and b) an organic polymer phase. The copolymerization of at least one compound of the formula I [(ArO)mMOnRrHp]q  (I) in which M is B, Al, Ga, In, Si, Ge, Sn, P, As or Sb, Ar is phenyl or naphthyl, R is alkyl, alkenyl, cycloalkyl or aryl, where aryl is unsubstituted or may have one or more substituents, with formaldehyde or formaldehyde equivalents, in a reaction medium which is essentially anhydrous, to obtain a composite material having an arrangement of phase domains similar to those nanocomposite materials obtainable by twin polymerization, and to the use of the composite material for production of gas storage materials, rubber mixtures, low-K dielectrics and electrode materials for lithium ion batteries.
US08865853B2 Poly(ureaurethane)s, articles and coatings prepared therefrom and methods of making the same
The present invention provides polyurethanes including a reaction product of components including: (a) an isocyanate functional urethane prepolymer comprising a reaction product of components including: (i) about 1 equivalent of at least one polyisocyanate; and (ii) about 0.1 to about 0.5 equivalents of at least one diol having 2 to 18 carbon atoms; and (b) about 0.05 to about 0.9 equivalents of at least one branched polyol having 4 to 18 carbon atoms and at least 3 hydroxyl groups; and (c) up to about 0.9 equivalents of at least one polyol different from branched polyol (b) and having 2 to 18 carbon atoms, wherein the reaction product components are essentially free of polyester polyol and polyether polyol; compositions, coatings and articles made therefrom and methods of making the same.
US08865849B2 Polyethylene and process for production thereof
This invention relates to a process for polymerizing olefins in which the amount of trimethylaluminum in a methylalumoxane solution is adjusted to be from 1 to 25 mol %, prior to use as an activator, where the mol % trimethylaluminum is determined by 1H NMR of the solution prior to combination with any support. This invention also relates to a process for polymerizing olefins in which the amount of an unknown species present in a methylalumoxane solution is adjusted to be from 0.10 to 0.65 integration units prior to use as an activator, where the amount of the unknown species is determined by the 1H NMR spectra of the solution performed prior to combination with any support. Preferably, the methylalumoxane solution is present in a catalyst system also comprising a metallocene transition metal compound.
US08865846B2 Metallocene and half sandwich dual catalyst systems for producing broad molecular weight distribution polymers
Disclosed herein are polymerization processes for the production of olefin polymers. These polymerization processes can use a dual catalyst system containing a zirconium or hafnium based metallocene compound and a titanium based half-metallocene compound containing an indenyl group.
US08865844B2 Electrode, method of preparing the same, binder composition, lithium battery containing the electrode and the binder composition
An electrode including a binder comprising a waterborne polyurethane polymer compound and an electrode active material is provided. The waterborne polyurethane polymer compound improves the binding properties of the electrode. In addition, the polymer compound disperses well in water and is hardened through a crosslinking reaction to increase elastic force, thereby enabling adjustment of elastic and binding forces. As a result, a battery including the polymer compound has excellent recovery and charge/discharge properties.
US08865840B2 Reactive block copolymers
A process for making a block copolymer compatibilizer, comprising reacting an acrylic monomer that has functional groups with one or more vinyl monomers in the presence of a free radical initiator and a stable free radical to form a reaction product that includes residual unreacted acrylic monomer, and reacting one or more vinyl monomers with the reaction product to form a second block that incorporates the residual unreacted acrylic monomer. A blend composition comprising a first thermoplastic polymer, which has functional groups, a reactive block copolymer that has functional groups in two or more blocks, and a second thermoplastic polymer that is compatible with one block of the block copolymer, where the functional groups in the first thermoplastic react with the functional groups in the block copolymer.
US08865839B2 Polytetrafluoroethylene mixture
Provided is a material that can be easily biaxially oriented, homogeneously stretched even with a high draw ratio, and formed into a polytetrafluoroethylene porous membrane with low pressure loss. The present invention relates to a polytetrafluoroethylene mixture comprising: a modified polytetrafluoroethylene; and a fibrillable polytetrafluoroethylene homopolymer, the modified polytetrafluoroethylene having an extrusion pressure to a cylinder, at a reduction ratio of 1600, of 70 MPa or higher.
US08865838B2 Process for forming thermoplastic vulcanizates
Provided are methods for producing a thermoplastic vulcanizate. One method includes charging vulcanizable rubber to a reactor; charging a masterbatch of thermoplastic resin and a catalyst for a phenolic resin curative to the reactor; charging a phenolic resin curative to the reactor; and dynamically vulcanizing the rubber with the phenolic resin curative in the presence of the catalyst. Also provided are thermoplastic vulcanizates made by the methods of the invention.
US08865837B2 Organosilicon compounds, production processes thereof, pressure-sensitive adhesive compositions containing the organosilicon compounds, self-adhesive polarizers and liquid crystal displays
Organosilicon compounds are represented by the following formula: wherein R is a hydrolyzable group, R′ is an alkyl having 1 to 4 carbon atoms, A is an alkylene having 1 to 6 carbon atoms, X is O or S, Y is —NH— or S, L1 and L2 are C or N, Z and M are —NH—, O or S, R1 to R11 are H, alkyl having 1 to 6 carbon atoms, alkoxy or fluoroalkyl, or amino, m is 1 to 3, and n is 0 to 3. R1 and R2 or R2 and R3 may bonded together. R5 and R6 or R9 and R10 may directly bond together. R4 and R7 or R8 and R11 may form a ring skeleton. Their production processes, pressure-sensitive adhesive compositions, self-adhesive polarizers and LCDs are also disclosed.
US08865835B2 Solar cell sealing material and solar cell module produced using the same
There is provided an encapsulant material for solar cells which facilitates production of a solar cell module and is excellent in flexibility, heat resistance, transparency, etc., and a solar cell module produced using the encapsulant material. The present invention relates to an encapsulant material for solar cells which includes a resin composition (C) containing an ethylene-α-olefin random copolymer (A) capable of satisfying the following condition (a) and an ethylene-α-olefin block copolymer (B) capable of satisfying the following condition (b): (a) a heat of crystal fusion is from 0 to 70 J/g as measured in differential scanning calorimetry at a heating rate of 10° C./min; and (b) a crystal fusion peak temperature is 100° C. or higher and a heat of crystal fusion is from 5 to 70 J/g as measured in differential scanning calorimetry at a heating rate of 10° C./min.
US08865832B2 Tin-free aqueous polyurethane dispersions
The present invention relates to radiation-curable coating compositions based on tin-free aqueous polyurethane dispersions based on polyurethane acrylates (i), characterized in that the polyurethane acrylate (i) comprises as builder componentsA) one or more compounds with at least one group which is reactive towards isocyanate and at least one unsaturated group which can undergo free radical polymerization,B) one or more compounds which differ from A) and have at least one group which is reactive towards isocyanate,C) one or more compounds with at least one group which is reactive towards isocyanate and additionally at least one group having a hydrophilizing action,D) one or more organic polyisocyanates,which are reacted in the presence ofF) bismuth(III) salt(s) andG) an acid having a pKa of <2.5,and a process for the preparation thereof, the use of the coating compositions as lacquers and/or adhesives, and objects and substrates provided with these lacquers and/or adhesives.
US08865831B2 Two-component coating compositions
The present invention relates to isocyanate-curing two-component coating compositions containing urethane compounds having at least two —O—CO—NH-groups.The invention relates to coating compositions comprising A) at least one binder having functional groups containing active hydrogen, B) at least one polyisocyanate crosslinking agent having free isocyanate groups and C) at least one urethane compound having at least two —O—CO—NH-groups, wherein the urethane compound has a number-average molecular mass Mn of from 400 to 5,000 and is substantially free from functional groups which are capable of entering into a crosslinking reaction with components A) and/or B). Preferred urethane compounds C) are obtained by reacting polyisocyanate compounds with monohydroxy compounds.
US08865830B2 Curable organosiloxane block copolymer emulsions
The present disclosure provides aqueous silicone emulsions of a “resin-linear” organosiloxane block copolymers. The present disclosure further provides a process for making these emulsions by forming a mixture of an organosiloxane block copolymer, admixing a sufficient amount of water to the mixture from to form an emulsion, and optionally further shear mixing the emulsion. The present invention further relates to the cured and/or coating compositions prepared from the present emulsions.
US08865829B2 Functionalized polymer, rubber composition and pneumatic tire
There is disclosed a functionalized elastomer comprising the reaction product of a living anionic elastomeric polymer; anda polymerization terminator of formula I where R1, R2 and R3 are independently C1 to C8 alkyl or C1 to C8 alkoxy, with the proviso that at least two of R1, R2 and R3 are C1 to C8 alkoxy; R4 is C1 to C8 alkyl; Si is silicon; S is sulfur; and Z is R5 or of formula II where R5 is alkyl, aryl, alkylaryl or arylalkyl. There is further disclosed a rubber composition comprising the functionalized elastomer, and a pneumatic tire comprising the rubber composition.
US08865828B2 Method for producing permeable water-absorbing polymer particles through polymerization of drops of a monomer solution
A process for producing water-absorbing polymer particles by polymerizing droplets of a monomer solution in a surrounding gas phase, wherein the polymer particles are coated with a permeability improver.
US08865827B2 Sulfonic acid monomer based compositions
The present invention relates to a composition comprising a water-soluble dispersant comprising structural units of a sulfonic acid monomer or a salt thereof and a co-monomer. The dispersant of the present invention addresses a need in the art by providing a way to improve the hiding efficiency of coatings compositions.
US08865824B2 Hot melt adhesive
A hot melt adhesive material and articles made using the hot melt adhesive to assemble structures in an article. The adhesive material typically is manufactured by blending amorphous polymer with a heterophase polymer having crystallinity into an adhesive composition.
US08865823B2 Triblock copolymer, method for its formation, and compatibilized compositions comprising it
A poly(phenylene ether)-poly(hydroxy ether)-poly(phenylene ether) (PPE-PHE-PPE) triblock copolymer is formed by reaction of a monohydroxy-terminated poly(phenylene ether) with a diepoxy-terminated poly(hydroxy ether) in the presence of a base. The PPE-PHE-PPE triblock copolymer is useful as a compatibilizer in blends of polar polymers and non-polar polymers. The PPE-PHE-PPE triblock copolymer is also useful as a compatibilizer for non-polar polymers and polar fillers.
US08865820B2 Fluorine-containing curable composition and rubber article
A fluorine-containing curable composition which is less viscous, and which can produce a cured article having excellent heat resistance, chemical resistance, solvent resistance, and mechanical strength is provided. The fluorine-containing curable composition comprises (a) 100 parts by weight of a straight chain fluorine-containing polymer having at least two alkenyl groups per molecule represented by the following formula (1): said polymer having a number average molecular weight of 1,000 to 100,000; (b) a fluorine-containing organosilicon compound having at least 2 hydrogen atoms bonded to the silicon atom per molecule at an amount such that molar ratio of hydrosilyl group (SiH group) in the component (b) to the alkenyl group in the component (a) is in the range of 0.4 to 5.0; (c) a catalytic amount of a hydrosilylation catalyst; and (d) 1 to 100 parts by weight of a silica filler.
US08865818B2 Additive for improving the solvent resistance and other properties of water-based binder systems
Aqueous dispersions which comprise nanoscale ZnO particles and nanoscale particles of a non-ZnO metal oxide, semimetal oxide or oxo salt are used in aqueous binder systems, such as coating materials, adhesives, sealants and binders, to improve the solvent resistance of the dried or cured binder system, and to improve other properties.
US08865811B2 Polyphenylene ether, resin composition, and molded body of resin composition
The polyphenylene ether according to the present invention includes 5 to 20% by mass of a component having a molecular weight of 50,000 or more and 12 to 30% by mass of a component having a molecular weight of 8,000 or less. The resin composition according to the present invention includes the polyphenylene ether (a) and a hydrogenated block copolymer (b) prepared by hydrogenating a block copolymer including at least two polymer blocks A having a vinyl aromatic compound and at least one polymer block B having a conjugated diene compound, wherein the number average molecular weight (Mnb) of the hydrogenated block copolymer is 100,000 or less, and the number average molecular weight (MnbA) of at least one polymer block of the polymer blocks A is 8,000 or more.
US08865808B2 Halogen-free, flame retardant TPU composite
Halogen-free TPU compositions comprise in weight percent based on the weight of the composition: A. 1 to 99% thermoplastic polyurethane (TPU), B. 1 to 50% tris(2-butoxyethyl)phosphate (TBEP), C. 1 to 70% metal hydrate, and D. 1 to 70% organic phosphate ester other than tris(2-butoxyethyl)phosphate. These compositions exhibit better smoke suppression as compared with conventional organic phosphate flame retardant TPU compositions such as those based on resorcinol bis(diphenyl phosphate) (RDP) and bisphenol-A bis(diphenyl phosphate) (BPADP) in the absence of TBEP.
US08865802B2 Chemical modification of lignin and lignin derivatives
In one example implementation, a trans-esterified APL can include an APL and a polyester including polyester chains. The polyester may be an aliphatic polyester, a semi-aromatic polyester, or an aromatic polyester. In other examples, an acetate ester of the APL can be used to swap carboxylic acid groups with the alcohol oligomer units in the polyester chains.
US08865798B2 Self healing composite material and method of manufacturing same
A self-healing material comprises a matrix embedded with micro-pockets of a healing-agent releasable by a crack in the matrix. The healing-agent is able to bond to the matrix to repair the crack. The healing-agent is contained in microcapsules. A corresponding catalyst for the healing-agent is embedded in the matrix and contained in a plurality of microcapsules as an emulsion. The emulsion comprises an oil, a perfluorated solvent, a hydrophobic ionic liquid, or mixtures thereof. A method of manufacturing the self-healing material comprises the steps of identifying an operational temperature range of the material, providing at least one substance as the healing-agent, which substance remaining substantially in a liquid state within the operational temperature range, identifying an operational evaporation rate of the healing-agent and providing the substance with a curing time according to the evaporation rate.
US08865797B2 Hybrid particle composite structures with reduced scattering
A core-shell composite particle for incorporation into a composite wherein the composite has improved transparency is disclosed. The core-shell composite particle includes a core material having a first refractive index and a shell material having a second refractive index where the core-shell particle has an effective refractive index determined by the first refractive index and the second refractive index. The effective refractive index is substantially equal to the refractive index of the envisioned embedding medium. Methods of forming the core-shell particles are also disclosed.
US08865795B1 Copier/printer exterior part using halogen-free flame-retardant resin composition including recycled polycarbonate and recycled polyethylene terephthalate
A copier/printer exterior part uses a halogen-free flame-retardant resin composition. The halogen-free flame-retardant resin composition includes 5 wt % to 50 wt % of unused polycarbonate, 20 wt % to 63 wt % of recycled polycarbonate, 5 wt % to 35 wt % of recycled polyethylene terephthalate, 0.2 wt % to 2 wt % of a styrene-acrylonitrile-glycidyl methacrylate terpolymer, 5 wt % to 15 wt % of a toughener, 10 wt % to 20 wt % of a flame retardant, 0.1 wt % to 0.8 wt % of a flame-retardant antidrip agent, 0.1 wt % to 1 wt % of an antioxidant, and 0.1 wt % to 2 wt % of a lubricant. The styrene-acrylonitrile-glycidyl methacrylate terpolymer includes 1 wt % to 5 wt % of glycidyl methacrylate and 20 wt % to 33 wt % of acrylonitrile.
US08865792B2 Medical glue and method of its production
This invention relates to medicine, more specifically, to surgical devices, and can be used for gluing soft body tissues. The medical glue comprises 3-methacryloxysulpholane, N-butyl-2-cyanoacrylate and at least one stabilizer.
US08865791B2 Endodontic sealing composition
This invention relates to a composition resulting from the mixture of a solid phase, comprising at least one calcium derivative powder in association with at least one radioopacifier and at least one polymer and optionally at least one non-radioopaque filler, all in powder form; and aqueous phase comprising water, at least one water-reducing agent, and at least one set accelerator; the ratio of solid phase to liquid phase ranging from 1.0 to 2.5, preferably from 1.5 to 2.2, more preferably from 2 to 2.15; said composition having a compressive strength of less than 40 MPa, preferably ranging from 1 to 15 MPa, preferably ranging from about 3 to about 12 MPa; this invention also relates to a kit and a method for the manufacture of the composition, and to a method for treating or retreating a canal root.
US08865789B2 Silicone hydrogel contact lenses
Silicone hydrogel contact lenses that have good dimensional stability, are ophthalmically-acceptable, and can be manufactured without the use of alcohol solvents are formed from the reaction product of a polymerizable composition comprising at least one mono-functional acrylate-containing siloxane monomer having a molecular weight of less than 2,000; at least one bi-functional acrylate-containing siloxane monomer having a molecular weight of at least 3,000; and at least one hydrophilic vinyl-containing monomer, wherein the polymerizable composition has a molar ratio of total amount of mono-functional acrylate-containing siloxane monomer to total amount of bi-functional acrylate-containing siloxane monomer of at least 30:1, respectively.
US08865788B2 Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices
A medical prosthesis for use within the body which is formed of radiation treated ultra high molecular weight polyethylene having substantially no detectable free radicals, is described. Preferred prostheses exhibit reduced production of particles from the prosthesis during wear of the prosthesis, and are substantially oxidation resistant. Methods of manufacture of such devices and material used therein are also provided.
US08865786B2 Antireflective coating compositions
Coating compositions, and methods for depositing them on the surface of an article to produce an antireflection coating, are disclosed. In one embodiment, the coating composition includes a (meth)acrylate-functional silicon alkoxide, silica particles, a (meth)acrylate monomer, an epoxy (meth)acrylate oligomer, a photoinitiator, a solvent, an acid, and water. The relative amounts of these constituents are controlled such that, when the coating composition is deposited onto the surface of an article and cured, it has a refractive index less than about 1.60 at a wavelength of 510 nm. In another embodiment, the coating composition includes an organo-metallic compound other than an organo-metallic compound of silicon, an epoxy-functional silicon alkoxide, a non-epoxy-functional silicon alkoxide, a curing agent compatible with epoxy-functional molecules, a solvent, an inorganic acid, and water. The relative amounts of these constituents are controlled such that, when the coating composition is deposited onto the surface of an article and cured, it has a refractive index greater than about 1.70 at a wavelength of 510 nm. The coating compositions are deposited in a process that produces an antireflection coating in less than 90 minutes of processing time.
US08865784B2 Composition for silicone rubber foam, manufacturing method of silicone rubber foam, and silicone rubber foam
There are provided a composition for silicone rubber foam, a manufacturing method of a silicone rubber foam, and a silicone rubber foam in which it is possible to control the foaming states. The composition for silicone rubber foam contains: (A) 100 parts by mass of polyorganosiloxane having a degree of polymerization of 4,000 to 10,000 and having two or more alkenyl groups at a content of 0.001 mmol/g or more and less than 0.3 mmol/g; an amount of polyorganohydrogensiloxane having an average of two or more Si-atom-bonded hydrogen atoms so that a molar ratio of the hydrogen atoms to the alkenyl groups in the (A) component is 0.001 to 5; 0.1 to 10 parts by mass of an organic foaming agent with a decomposition temperature of 50 to 250° C.; 5 to 200 parts by mass of silica powder; and a catalyst amount of a platinum-based metal catalyst activated with ultraviolet rays.
US08865783B2 Flame retardant composition
A liquid flame retardant composition having one or more flame retarding agents, which are the epoxides obtainable by reacting tetrabromobisphenol A with epichlorohydrin and their end-capped derivatives represented by Formula (1), is provided. The liquid composition is especially useful in the preparation of rigid polyurethane foams.
US08865781B2 Processing of waste material
A method of processing waste carpet or matting material to separate constituent materials thereof, includes optionally drying the material and then cooling the material to a temperature at which at least one constituent material therein is embrittled. A mechanical force is applied to the cooled material causing the embrittled constituent material to break into fragments. Optionally, the material from the previous step is dried. The material is then separated to separate the fragments of constituent material from other constituent material. The carpet material can be initially shredded into coarse pieces. The procedure may be repeated optionally with different temperatures to selectively embrittle and fragment different components and facilitate their separation.
US08865780B2 Process for converting biogas to a gas rich in methane
Process for converting biogas to a gas rich in methane comprising the steps of: —mixing a carbon dioxide-comprising biogas with steam to form a mixture comprising carbon dioxide, methane and steam; electrolysing the mixture comprising carbon dioxide, methane and steam in a high temperature solid oxide electrolyser cell unit, to obtain a gas comprising mainly hydrogen and carbon monoxide; catalytically converting hydrogen and carbon monoxide in the gas comprising hydrogen and carbon monoxide to methane in one or more methanation steps to obtain a gas rich in methane.
US08865771B2 Amides useful as inhibitors of voltage-gated sodium channels
The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
US08865770B2 Carbamide peroxide treatments for the reproductive tract
Disclosed are methods of maintaining fertility or treating retained placenta, reproductive tract infection, or reproductive tract inflammation in an animal by administering carbamide peroxide to the reproductive tract of the animal. The carbamide peroxide administration removes placental remains on the uterine wall, protects against or treats reproductive tract infection, and protects against or treats reproductive tract inflammation such as metritis, and thereby maintains fertility in the animal.
US08865769B2 Baclofen and acamprosate based therapy of neurological disorders
The present invention relates to combinations and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid β toxicity. More specifically, the present invention relates to novel combinatorial therapies of Multiple Sclerosis, Alzheimer's disease, Alzheimer's disease related disorder, Amyotrophic Lateral Sclerosis, Parkinson's disease, Huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury, based on Baclofen and Acamprosate combination.
US08865767B2 Nutritional supplement composition promoting, increase, development, elevation and activation of “serotonin”
A Nutritional Supplement Composition promoting the increase, development, elevation and activation of the brain chemical “serotonin” in the “subjects” brain chemistry to improve mood, thought, emotions and, mental stability and functioning comprised of the constituents, Omega 3, Omega 6, Calcium Magnesium, and B-complex is described, as well as the method of administration, the usefulness of the present invention, and who would benefit from the administration of this present invention. This Nutritional Supplement composition may be used for all, in “age appropriate” dosages for different age “subjects”. This Nutritional Supplement Composition when administered daily will reduce and stabilize the “subjects” depression, anxiety, obsessive- compulsive behaviors stress related and other emotional and mental conditions. The above statement about the embodiment of the present invention will be further explained in more specific detail in the body of the description.
US08865762B2 Method for the treatment of bone diseases comprising colforsin daropate
The present invention relates to a pharmaceutical composition for the prevention or treatment of bone diseases comprising colforsin daropate, and more particularly, the present invention relates to a pharmaceutical composition for the prevention or treatment of bone diseases such as bone fracture and osteoporosis, which inhibits osteoclast differentiation and bone resorption caused by osteoclasts and promotes osteoblast differentiation and the activity of osteoblasts, and a health functional food composition comprising colforsin daropate.
US08865761B1 Regulation of cholesterol homeostasis
The invention provides novel compounds of Formulas (I)-(IV), as described herein. Also provided are compositions of these compounds, method of making the compounds, and methods of using the compounds. The compounds can be used to regulate cholesterol homeostasis and to treat conditions and diseases associated with cholesterol homeostasis, including lysosomal lipid storage disorders such as Niemann-Pick Disease type C.
US08865759B2 Use of dithiine-tetracarboximides for controlling phytopathogenic fungi
The present invention relates to the use of novel and of known dithiine-tetracarboximides for controlling phytopathogenic fungi, and to methods of controlling phytopathogenic fungi in plant protection, and to plant protection compositions comprising these dithiine-tetracarboximides.
US08865755B2 Dual-acting antihypertensive agents
In one aspect, the invention relates to compounds having the formula: wherein: Ar, r, Z, X, R3, and R5-7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
US08865752B2 Cytochrome P450 inhibitors and uses thereof
The present invention provides compounds having the general structural formula (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving fibrosis and proliferation, and where anti-fibrotic or anti-proliferative activity is beneficial.
US08865751B2 Thiazoles, imidazoles, and pyrazoles useful as inhibitors of protein kinases
The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and the compositions in the treatment of various disease, conditions, or disorders. The invention also relates to processes for preparing compounds of the inventions.
US08865749B2 Treatment and prevention of Th1 and ‘autoimmune’ diseases effected with antibiotics and/or angiotensin inhibition
This invention is a method of killing the stealthy intra-cellular bacteria which cause many Th1 and ‘Autoimmune’ diseases. The methods described in this invention will treat and prevent the diseases customarily named Diabetes Type 1, Diabetes Type 2, Rheumatic Arthritis, Reactive Arthritis, Osteo Arthritis, Psoriasis, Scleroderma, Osteoporosis, Atherosclerosis, Myocarditis, Endocarditis, Pericarditis, Alzheimer's, Cystic Fibrosis, Hashimoto's Thyroiditis, Graves Disease, Leprosy, Syphilis, Lyme, Chronic Lyme, Borreliosis, Neuro-borreliosis, Inflammatory Bowel Disease (IBD), Tuberculosis, Latent Tuberculosis, Sarcoidosis, Neurosarcoidosis, Lupus, Discoid Lupus, Lupus Pernio, Lupus Nephritis, Systemic Lupus Erythematosis (SLE), Asthma, Macular Degeneration, Uveitis, Crohn's, Irritable Bowel Syndrome, Sjogren's, Fibromyalgia, Chronic Fatigue Syndrom (CFS), Chronic Fatigue Immune Dysfunction Syndrome (CFIDS), Myalgic Encephalitis (ME), Amyotrophic Lateral Sclerosis (ALS), Parkinson's, Multiple Sclerosis, Autism Spectrum Disorder (ASD), Attention Deficit Disorder (ADD), and Attention Deficit Hyperactivity Disorder (ADHD). This invention achieves this by reducing the ability of the stealthy bacteria to produce proteins with their 70S Ribosome. The 30S and 50S subunits of the bacterial ribosome are targeted individually and collectively. Further, this invention reduces the availability of Angiotensin II to the host's Angiotensin receptors, conditioning the immune system to recognize and kill the bacteria. Finally, this invention reduces the availability of Angiotensin II and cytokines to the bacterial pathogens and thus inhibits the ability of their genome to scavenge (from a host patient) the amino acids, and other biochemicals necessary for bacterial survival.
US08865746B2 Methods of treating an overweight or obese subject
The invention herein generally relates to pharmaceutical formulations and methods of treating an overweight or obese subject, and overweight- or obesity-related conditions.
US08865744B1 (Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles
Disclosed are (cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles and their use as CB2 cannabinoid receptor agonists, pharmaceutical compositions containing the same, and their use for the treatment of CB2 receptor mediated disorders or conditions.
US08865743B2 Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
Compositions, systems and methods for administration of small volume sufentanil drug dosage forms to the sublingual mucosa of a subject for treatment of pain using a device are disclosed.
US08865742B2 Intermediate compounds and processes for the preparation of quinoline derivatives such as Laquinimod sodium
The present invention relates to processes for the preparation of quinoline-3-carboxamide derivatives, such as sodium 5-chloro-3-(ethylphenylcarbamoyl)-1-methyl-2-oxo-1,2-dihydroquinolin-4-olate (Laquinimod sodium). The present invention further relates to intermediates formed in such processes.
US08865739B2 Substituted heterocyclic compounds as ion channel modulators
The present invention relates to sodium channel inhibitors of Formula (I): in which R1, R2, R3, R4, R5, X, Y, and Z are as defined herein, and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. The invention also relates to methods for the preparation of the compounds, and to pharmaceutical compositions containing such compounds.
US08865738B2 5-membered heterocyclic compound cyclopenta[C]pyrrolylalkylcarbamate derivatives, preparation thereof, and therapeutic use thereof
The invention relates to compounds of the general formula (I) where: R2 is a hydrogen or fluorine atom or a hydroxyl, cyano, trifluoromethyl, C1-6-alkyl, C1-6-alkoxy, or NR8R9 group; m and p have a value of 1; n and o have the same value which is 0 or 1; A is a covalent bond or a C1-8-alkylene group; R1 is an optionally substituted aryl or heteroaryl group; R3 is a hydrogen or fluorine atom or a C1-6-alkyl group or a trifluoromethyl group; R4 is an optionally substituted 5-membered heterocyclic compound; wherein the compounds can be in the state of a base or an acid addition salt. The present invention can be used in therapeutics.
US08865730B2 Polymorphic forms of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
Polymorphs of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one, compositions thereof, methods for their preparation, and methods for their use are disclosed.
US08865726B2 Substituted pyrazolo[1,5-a]pyrimidine compounds as mTOR inhibitors
Compounds of Formula I: and salts thereof in which R1, R2, R2a, R3, n, X and ring B have the meanings given in the specification, are inhibitors of mTOR and are useful in the treatment of diseases which are sensitive to inhibition of mTOR, such as cancers.
US08865725B2 Substituted imidazopyrimidin-5(6H)-ones as allosteric modulators of MGLUR5 receptors
In one aspect, the invention relates to imidazopyrimidin-5(6H)-one analogs, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US08865724B2 Preparation of 2-methyl-4-amino-5(substituted-1H-1,2,3-triazolyl)methylpyrimidine derivatives and microbicidal activity thereof
Disclosed is a derivative of 2-methyl-4-amino-5-(substituted-1H-1,2,3-triazol)methylpyrimidine of general formula I and microbicidal activity thereof. In the formula, R1 represents hydrogen, I; X represents O or NH; Y represents phenyl of substituted phenyl, benzoyl or substituted benzoyl, phenyloxyacetyl or substituted phenyloxyacetyl; the substituents on the phenyl rings which Y involves are: H, halogen, nitro, cyano, CF3, C1˜4 alkyl, methoxyl, C1˜2 carboxyl or carboxylic ester groups; any position of phenyl rings can be mono- or multi-substituted by identical or different substituents. The compound has a significant inhibition effect on cucumber bacterial angular leaf spot, tomato bacterial leaf spot, cucumber brown blot, cucumber downy mildew, rice sheath blight, Gibberella saubinetii, Alternaria solani, Botrytis cinerea, Alternaria alternate and Colletotrichum orbiculare and it can be used as an effective ingredient of microbicides.
US08865721B2 Delta opioid receptor agonist compounds
Compositions and methods for treatment of sexual dysfunctions by administering to a subject a pharmaceutical composition comprising a delta opioid receptor agonist in an amount effective to delay the onset of ejaculation in the subject during sexual stimulation.
US08865716B2 Dihydropteridinones II
The present invention relates to spiroheterocycl-dihydropyrimidines, their use as modulators of γ-secretase and to pharmaceutical compositions containing said compounds. In particular, the present invention relates to compounds which interfere with γ-secretase and/or its substrate and therefore modulate the formation of Aβ peptides.
US08865714B2 Piperazine compound capable of inhibiting prostaglandin D synthase
This invention relates to a piperazine compound represented by Formula (I), wherein R1 is C1-6 alkyl; R2 is hydroxy, C1-6 alkyl that may have one or more substituents, —(C═O)—N(R3)(R4), or —(C═O)—OR5; R3 and R4 are the same or different, and each represents hydrogen or C1-6 alkyl that may have one or more substituents, or R3 and R4, taken together with a nitrogen atom to which R3 and R4 are attached, may form a saturated heterocyclic group; R5 is hydrogen or C1-6 alkyl that may have one or more substituents; and n is 1 or 2; or a salt thereof.
US08865713B2 Benzoimidazoles as prolyl hydroxylase inhibitors
The present invention is directed to benzoimidazole compounds of the formula: and enantiomers, diastereomers, racemates, and pharmaceutically acceptable salts thereof. Compounds of the present invention are useful in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions modulated by prolyl hydroxylase activity.
US08865708B2 Methods and compositions for inhibition of the transitional endoplasmic reticulum ATPase
Compounds of Formulas I-XLIII are identified as direct inhibitors of p97 ATPase or of the degradation of a p97-dependent ubiquitin-proteasome system (UPS) substrate. Methods and compositions are disclosed for inhibiting p97 ATPase and the degradation of a p97-dependent UPS substrate, and for identifying inhibitors thereof.
US08865705B2 Benzimidazole respiratory syncytial virus inhibitors
Benzimidazoles having inhibitory activity on RSV replication and having the formula the prodrugs, N-oxides, addition salts, quaternary amines, metal complexes and stereochemically isomeric forms thereof, compositions containing these compounds as active ingredient and processes for preparing these compounds and compositions.
US08865699B2 Amino triazoles as PI3K inhibitors
The invention relates to compounds of formula (I) wherein X, T1 and R1 to R3 have the meaning as cited in the description and the claims. Said compounds are useful as protein kinase inhibitors, especially inhibitors of PI3K, for the treatment or prophylaxis of immunological, inflammatory, autoimmune, or allergic disorders. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the production of and use as medicaments.
US08865696B2 Morphine and morphine precursors
Methods and materials related to the use of morphine, morphine precursors (e.g., reticuline), and inhibitors of morphine synthesis or activity to treat diseases, to reduce inflammation, or to restore normal function are provided.
US08865694B2 Topical compositions for treatment of skin conditions
The invention provides a topical formulation adapted for treatment of a skin condition comprising (i) at least one retinoid; and (ii) salicylic acid or an ester, amide, salt, or solvate thereof. The invention also includes a kit for treatment of skin conditions comprising a retinoid and salicylic acid, as well as a method of treating skin conditions utilizing the inventive formulation and kit.
US08865691B2 Pharmaceutical compositions and methods of use 4-pregenen-11β-17-21-triol-3,20-dione derivatives
The present invention relates to pharmaceutical compositions comprising 4-pregenen-11β-17-21-triol-3,20-dione derivatives, and their use as pharmaceuticals as modulators of the glucocorticoid receptors (GR) and/or the mineralocorticoid receptors (MR). The invention relates specifically to the use of these compounds and their pharmaceutical compositions to treat ocular conditions associated with the glucocorticoid receptors (GR) and/or the mineralocorticoid receptors (MR).
US08865690B2 17alfa, 21-dihydroxypregnene esters as antiandrogenic agents
17α,21-Dihydroxypregna-4,9(11)-diene-3,20-dione and 17α,21-dihydroxypregna-4-ene-3,20-dione 17 and/or 21 esters thereof having remarkable antiandrogenic activity, and the processes for the preparation thereof.
US08865689B2 Methods and compositions for treating hyperuricemia and metabolic disorders associated with hyperuricemia
Methods and compositions for treating and/or preventing hyperuricemia or metabolic disorders associated with hyperuricemia comprising administering to a patient in need a therapeutically effective amount of diacerein, rhein, or a pharmaceutically acceptable salt, an analog, a prodrug, or an active metabolite thereof.
US08865688B2 Compositions and methods for treatment of bowel diseases with granulated mesalamine
Disclosed are methods for treating gastrointestinal disorders, e.g., Crohn's disease, ulcerative colitis, and diverticular disease, with a granulated mesalamine formulation. Some formulations use granulated mesalamine in capsule form. Also included are methods to extend remission of ulcerative colitis by administration of a once-daily dosage of granulated mesalamine.
US08865686B2 Tetracycline compounds as tyrosyl-DNA phosphodiesterase I inhibitors
The instant invention is directed towards tetracycline compositions, and methods of inhibiting Tdp1 activity, and methods of treating Tdp1-associated disorders.
US08865683B2 Active compound combinations having insecticidal properties
The invention relates to novel insecticidal active compound combinations comprising, firstly, anthranilamides (group 1) and, secondly, further insecticidal active compounds selected from the group of the (thio)phosphates (group 2) and/or the group of the carbamates (group 3), which combinations are highly suitable for controlling animal pests, such as insects.
US08865682B2 Substituted 3-(5-membered unsaturated heterocyclyl-1, 3-dihydro-indol-2-one's and derivatives thereof as kinase inhibitors
The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.
US08865680B2 Surgical gel system
A surgical gel system for coating and adhering to a wound area to control bleeding while supporting wound healing comprises polyanhydroglucuronic acid or a biocompatible salt in an amount of from 1% to 15% by weight and pectin in an amount of in an amount of from 0.1% to 9% by weight. The gel system may be used for stopping bleeding during or after sinus surgery, for stopping bleeding in ear nose and throat procedures, for stopping bleeding in gynecological procedures, or for stopping bleeding in internal organ procedures.
US08865675B2 Compositions and methods for silencing apolipoprotein B
The present invention provides compositions and methods for the delivery of interfering RNAs such as siRNAs that silence APOB expression in cells such as liver cells. In particular, the nucleic acid-lipid particles provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells such as liver cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of APOB at relatively low doses. In addition, the compositions and methods of the present invention are less toxic and provide a greater therapeutic index compared to compositions and methods previously known in the art.
US08865668B2 Methods and compositions for increasing RNA interference
The present invention relates to compositions containing a combination of a first active component comprising one or more sulfated polysaccharides and/or glycosaminoglycans and a second active component comprising one or more RNAi-inducing molecules, and methods for using these compositions to enhance double-stranded RNA (dsRNA)-mediated gene silencing in pest or pathogen species. The invention further relates to methods for controlling pests or pathogens, methods for preventing pest infestations or pathogen infections and methods for knocking down gene expression in pests or pathogens using the compositions and methods of the invention.
US08865666B2 Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof
This application relates to combination therapies including triciribine and related compounds and bortezomib and derivatives thereof analogs and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation.
US08865664B2 Hydrophobically enhanced aminoglycosides
Hydrophobically enhanced aminoglycosides have been prepared and shown to be effective antibacterial agents. These agents may be used in the treatment or prevention of various bacterial infections. Methods of preparing these agents also permit facile synthetic access. Formula (I).
US08865663B2 Method for the administration of anti-cancer drugs
An administration method comprising: determining a cancer type through (i) first data indicating that an Estrogen Receptor (ER) is negative and a Human Epidermal growth factor Receptor-2 (Her2) is negative, or (ii) second data indicating that at least one of the ER and the Her2 is positive; and when the cancer type is determined through (i) the first data indicating that the ER is negative and the Her2 is negative: first performing a docetaxel administration cycle comprising administrating docetaxel to a patient multiple times at certain intervals; and then performing a 5-fluorouracil, epirubicin, and cyclophosphamide (FEC) administration cycle comprising administrating 5-fluorouracil, epirubicin, and cyclophosphamide to the patient multiple times at certain intervals, and when the cancer type is determined through (ii) the second data indicating that at least one of the ER and Her2 is positive: first performing the FEC administration cycle; and then performing the docetaxel administration cycle.
US08865659B2 Compositions for prevention or treatment of Hepatitis C virus containing ginsenoside Rg3 as an active ingredient
This invention is for the compound containing ginsenoside Rg3 as an active ingredient to prevent and treat Hepatitis C virus infection. Specifically, the ginsenoside Rg3 of this invention demonstrated the predominant antiviral activities and apotosis actions in a dose-dependent manner in the Hepatitis C virus infected cells (Huh 7.5.1). Confirmed that it reduces the levels of TNF-α and thioredoxin significantly, and increases phospho-NFκB. It also demonstrated same effectiveness as PegInterferone alpha-2b(PegIFN a-2b, Hepatitis C therapeutics), and has no cytotoxicity to human bodies. Thus, it may be used safely as an active ingredient of medical/pharmaceutical and health food compounds for preventing or treating Hepatitis C.
US08865652B2 Method of treating solid cancers with pegylated IL-10
Provided are methods of treatment for tumors. In particular, methods are provided for use of a chemically modified IL-10 to treat tumors.
US08865651B2 Cosmetic anti-ageing skin care compositions
The invention is directed to an anti ageing skin care composition, more in particular a cosmetic anti aging skin care composition. The anti ageing skin care composition of the invention comprise, in a physiologically acceptable medium, (i) at least one peptide from Laminin-1 that is able to promote synthesis of Laminin-5; (ii) at least one peptide capable of at least partially inhibiting neuronal exocytosis; and (iii) at least one tripeptide producing a rapid and strong stimulation of collagen synthesis. The compositions of the present invention are effective in reducing existing wrinkles and/or preventing the formation of new wrinkles.
US08865649B2 Preparation for use of aspartate and vitamin B12 or biotin for regulating ketone bodies
It has been found that high amounts of aspartate equivalents in combination with vitamin B12 and/or biotin, especially in relative absence of glutamate equivalents, improve the metabolism of ketobodies and/or lactate in a mammal's body, especially in diseased or traumatic conditions. As a result, levels of ketobodies and lactate can be decreased and unphysicologically high acidity normalised. Thus, it is an object of the invention to provide an enteral nutritional or a pharmaceutical composition for the treatment and/or prevention of disturbed ketone and lactate metabolism, i.e. elevated concentrations of ketone bodies, lactate and/or other organic acids and/or insufficient pH homeostasis, especially elevated concentrations of ketone bodies and/or lactate, in a mammal's blood, wherein the composition comprises high amounts of aspartate equivalents in combination with vitamin B12 and/or biotin, preferably in relative absence of glutamate equivalents.
US08865648B2 Monomeric and dimeric forms of adiponectin receptor fragments and methods of use
Methods are disclosed for determining progression of a condition, onset of a condition, or efficacy of treatment of a condition characterized by an adipocyte imbalance in a patient. In addition, methods are disclosed of treating diabetes, abnormal adipocyte activity, and insulin resistance using monomeric, homodimeric, and heterodimeric forms of certain C-terminal fragments of adiponectin receptor. In addition, methods of treating abnormal adipocyte activity, treating metabolic syndrome, causing insulin secretion, increasing insulin levels, inhibiting insulin degradation enzyme, treating Alzheimer's disease, treating cardiovascular disease associated with adiponectin levels, inhibiting ADAM-17 enzyme, inhibiting a protease, treating a condition associated with TNF-alpha, and treating a condition associated with HER2-neu are disclosed. Compositions, dosage forms, and kits are also disclosed.
US08865647B2 Pharmaceutical solution of non covalently bound albumin and acylated insulin
If albumin is added to a pharmaceutical formulation containing acylated insulin described in WO 2009/022005 and WO 2009/022013, the acylated insulin can be kept in solution after subcutaneous injection.
US08865642B2 Natural plant products for control of cancer metastasis
The invention provides compositions comprising soluble extracts or isolated polypeptides from the edible roots of the plant Colocasia, such as Colocasia esculenta, commonly known as Taro, and from Xanthosoma, such as Xanthosoma sagittifolium, commonly known as Malanga Blanca or Yautia. The compositions exhibit inhibitory effects on metastasis of cancer cells in particular breast and prostate cancer cells and have therapeutic pharmacological activity, Pharmaceutical compositions for the treatment of cancer by inhibiting metastasis which comprises an effective amount of the described extract or isolated polypeptide thereof and optionally a pharmaceutical acceptable carrier are described.
US08865640B2 Fatty acid chain saturation in alkanol amine based esterquat
A composition comprising an esterquat that is a quaternized reaction product of an alkanol amine and a fatty acid having a ratio of fatty acid to alkanol amine of 1.5 to 1.75, wherein 45 to 75% by weight of the fatty acids are saturated. Also, a method of softening a fabric and increasing fragrance delivery comprising treating the fabric with the composition.
US08865639B2 Use of a copolymer as thickener in liquid detergents having lower graying tendency
The invention relates to copolymers which contain a) at least 15% by weight units of an ethylenically unsaturated carboxylic acid, b) at least 15% by weight units of a C4-C8-alkylacrylats, c) less than 5% by weight units of methyl methacrylate, and are used as thickeners in liquid textile detergents. The copolymers can additionally contain units of a non-ionic ethylenically unsaturated surfactant monomer that are incorporated by polymerization. The thickeners are characterized by high thickening action, high shear thinning and low graying of the laundry after the washing process.
US08865637B2 Variants of a lysozyme and polynucleotides encoding same
The present invention relates to variant lysozymes. The present invention also relates to polynucleotides encoding the variant lysozymes and to nucleic acid constructs, vectors, and host cells comprising the polynucleotide.
US08865634B2 4-alkyl substituted pyridines as odiferous substances
The present invention primarily concerns certain 4-alkyl pyridines of the following formula (I), wherein R is C8-C12 alkyl, odiferous substance mixtures and aromatic substance mixtures containing these 4-alkyl pyridines, the respective uses thereof as an odiferous or aromatic substance (mixture) and corresponding perfumed products.
US08865626B2 Synergistically active herbicidal agents that are compatible with cultivated plants and contain herbicides from the group of benzoylpyrazoles
Synergistic and crop-plant-compatible herbicidal compositions comprising herbicides from the group of the benzoylpyrazolesHerbicidal compositions comprising A) a compound from the group of the benzoylpyrazoles, B) at least one further herbicide and C) optionally at least one safener are described as herbicides effective against monocotyledonous and/or dicotyledonous harmful plants. Compared to the herbicides applied individually, these compositions have superior activity, and at the same time they are highly compatible with crop plants.
US08865610B2 Phosphinyl guanidine compounds, metal salt complexes, catalyst systems, and their use to oligomerize or polymerize olefins
The present application relates to N2-phosphinyl guanidine metal salt complexes. The present application also relates to catalyst systems comprising N2-phosphinyl guanidine metal salt complexes and processes for making catalyst systems comprising N2-phosphinyl guanidine metal salt complexes. The present application also relates to utilizing N2-phosphinyl guanidine metal salt complexes in processes of oligomerizing or polymerizing olefins.
US08865609B2 Hydrogenation catalysts
The present invention relates to catalysts, to processes for making catalysts and to chemical processes employing such catalysts. The catalysts are preferably used for converting acetic acid to ethanol. The catalyst comprises a precious metal and one or more active metals on a modified support. The modified support may comprise cobalt tungstate.
US08865608B2 Turndown thermocompressor design for continuous catalyst recovery
Systems and processes for regenerating catalyst are provided herein that include a catalyst regeneration tower having a cooling zone that receives a catalyst cooling stream generated by a cooling gas loop. The systems and processes include a first thermocompressor that utilizes a first motive vapor and a second thermocompressor that utilizes a second motive vapor in order to provide the catalyst cooling stream to the regeneration tower. The second thermocompressor operates in parallel with the first thermocompressor. The first thermocompressor can utilize combustion air as the motive vapor. The second thermocompressor can utilize nitrogen as the motive vapor.
US08865597B2 Ta—TaN selective removal process for integrated device fabrication
Disclosed are a method and a system for processing a semiconductor structure of the type including a substrate, a dielectric layer, and a TaN—Ta liner on the dielectric layer. The method comprises the step of using XeF2 to remove at least a portion of the TaN—Ta liner completely to the dielectric layer. In the preferred embodiments, the present invention uses XeF2 selective gas phase etching as alternatives to Ta—TaN Chemical Mechanical Polishing (CMP) as a basic “liner removal process” and as a “selective cap plating base removal process.” In this first use, XeF2 is used to remove the metal liner, TaN—Ta, after copper CMP. In the second use, the XeF2 etch is used to selectively remove a plating base (TaN—Ta) that was used to form a metal cap layer over the copper conductor.
US08865596B2 Methods for forming semiconductor structures using selectively-formed sidewall spacers
Methods for forming semiconductor structures using selectively-formed sidewall spacers are provided. In one method, a first structure and a second structure is formed. The second structure has a height that is greater than the first structure's height. A first sidewall spacer-forming material is deposited overlying the first structure and the second structure. A second sidewall spacer-forming material is deposited overlying the first sidewall spacer-forming material. A composite spacer is formed about the second structure, the composite spacer comprising the first sidewall spacer-forming material and the second sidewall spacer-forming material. The second sidewall spacer-forming material is removed from the first structure and the first sidewall spacer-forming material is removed from the first structure.
US08865594B2 Formation of liner and barrier for tungsten as gate electrode and as contact plug to reduce resistance and enhance device performance
The invention provides a method of forming a film stack on a substrate, comprising performing a silicon containing gas soak process to form a silicon containing layer over the substrate, reacting with the silicon containing layer to form a tungsten silicide layer on the substrate, depositing a tungsten nitride layer on the substrate, subjecting the substrate to a nitridation treatment using active nitrogen species from a remote plasma, and depositing a conductive bulk layer directly on the tungsten nitride layer.
US08865593B2 Metal silicide layer, NMOS transistor, and fabrication method
Exemplary embodiments provide materials and methods for forming a metal silicide layer and/or an NMOS transistor. The metal silicide layer can be formed by heating a metal layer containing at least a tellurium element on a semiconductor substrate. The metal silicide layer can thus contain at least the tellurium element on the semiconductor substrate. The metal silicide layer can be formed in an NMOS transistor. With the addition of tellurium element in the metal silicide layer, Schottky barrier height between the metal silicide layer and the underling semiconductor substrate can be reduced. Contact resistance of the NMOS transistor can also be reduced.
US08865592B2 Silicided semiconductor structure and method of forming the same
A preferred embodiment includes a method of manufacturing a fuse element that includes forming a polysilicon layer over a semiconductor structure, doping the polysilicon layer with carbon or nitrogen, depositing a metal over the polysilicon layer; and annealing the metal and polysilicon layer to form a silicide in an upper portion of the polysilicon layer.
US08865591B2 N-type contact electrode formed on an N-type semiconductor layer and method of forming same using a second metal electrode layer heat-treated after being formed on a first, heat-treated metal electrode layer
A method for forming an n-type contact electrode, which includes an n-type nitride semiconductor such as AlxInyGazN (with x, y, and z being rational numbers that sum to 1.0 and fulfill the relations 0
US08865589B2 Semiconductor device and manufacturing method of semiconductor device
According to one embodiment, a semiconductor device includes a plurality of wires arranged in parallel at a predetermined pitch, a plurality at first contacts that are each connected to an odd-numbered wire among the wires and are arranged in parallel in an orthogonal direction with respect to a wiring direction of the wires, and a plurality of second contacts that are each connected to an even-numbered wire among the wires and are arranged in parallel in an orthogonal direction with respect to the wiring direction of the wires in such a way as to be offset from the first contacts in the wiring direction of the wires, in which the first contacts are offset from the second contacts by a pitch of the wires in an orthogonal direction with respect to the wiring direction of the wires.
US08865583B2 Manufacturing method of a semiconductor device and method for creating a layout thereof
A method for manufacturing a semiconductor device of one embodiment of the present invention includes: forming an insulation layer to be processed over a substrate; forming a first sacrificial layer in a first area over the substrate, the first sacrificial layer being patterned to form in the first area a functioning wiring connected to an element; forming a second sacrificial layer in a second area over the substrate, the second sacrificial layer being patterned to form in the second area a dummy wiring; forming a third sacrificial layer at a side wall of the first sacrificial layer and forming a fourth sacrificial layer at a side wall of the second sacrificial layer, the third sacrificial layer and the fourth sacrificial layer being separated; forming a concavity by etching the insulation layer to be processed using the third sacrificial layer and the fourth sacrificial layer as a mask; and filling a conductive material in the concavity.
US08865582B2 Method for producing a floating gate memory structure
Disclosed are methods for manufacturing floating gate memory devices and the floating gate memory devices thus manufactured. In one embodiment, the method comprises providing a monocrystalline semiconductor substrate, forming a tunnel oxide layer on the substrate, and depositing a protective layer on the tunnel oxide layer to form a stack of the tunnel oxide layer and the protective layer. The method further includes forming at least one opening in the stack, thereby exposing at least one portion of the substrate, and cleaning the at least one exposed portion with a cleaning liquid. The method still further includes loading the substrate comprising the stack into a reactor and, thereafter, performing an in-situ etch to remove the protective layer, using the at least one exposed portion as a source to epitaxially grow a layer comprising the monocrystalline semiconductor material, and forming the layer into at least one columnar floating gate structure.
US08865577B2 Method for making epitaxial structure
A method for making epitaxial structure is provided. The method includes providing a substrate having an epitaxial growth surface, growing a buffer layer on the epitaxial growth surface; placing a graphene layer on the buffer layer; epitaxially growing an epitaxial layer on the buffer layer; and removing the substrate. The graphene layer includes a number of apertures to expose a part of the buffer layer. The epitaxial layer is grown from the exposed part of the buffer layer and through the apertures.
US08865573B2 Method for fabricating semiconductor device
A method for fabricating a semiconductor device include forming devices on a front side of a semiconductor substrate, forming a hydrogen-containing layer on a back side of the semiconductor substrate, forming an outgassing prevention layer over the hydrogen-containing layer, and performing a hydrogen treatment process to diffuse hydrogen, contained in the hydrogen-containing layer, into the semiconductor substrate.
US08865572B2 Dislocation engineering using a scanned laser
A system for manipulating dislocations on semiconductor devices, includes a moveable laser configured to generate a laser beam locally on a surface portion of the semiconductor body having a plurality of dislocations, the moveable laser being characterized as having a scan speed, the moveable laser manipulates the plurality of dislocations on the surface portion of the semiconductor body by adjusting the temperature and the scan speed of the laser beam.
US08865568B2 Workpiece cutting method
Fractures (17a, 17b) are generated from modified regions (7a, 7b) to front and rear faces (12a, 12b) of a object to be processed (1), respectively, while an unmodified region (2) is interposed between the modified regions (7a, 7b). This can prevent fractures from continuously advancing in the thickness direction of a silicon substrate (12) when forming a plurality of rows of modified regions (7). By generating a stress in the object (1), the fractures (17a, 17b) are connected to each other in the unmodified region (2), so as to cut the object (1). This can prevent fractures from meandering in the rear face (12b) of the object (1) and so forth, whereby the object (1) can be cut accurately along a line to cut the object (5).
US08865564B2 Process for producing vertical interconnections through structured layers
A process is provided for producing at least one interconnecting well to achieve a conductive pathway between at least two connection layers of a component comprising a stack of at least one first substrate and one second substrate which are electrically insulated from one another, the process including defining a surface contact region of a surface connection layer over a surface of the stack and of at least one first contact region embedded in the stack starting from a first embedded connection layer of the first substrate. A region devoid of material is positioned between the first substrate and second substrates and which comprises a stage of producing a interconnecting well which passes through the second substrate and extends between the surface contact region and the first embedded contact region and passes through the region devoid of material, and also a first layer which covers the first embedded connection layer.
US08865550B2 Memory device having buried bit line and vertical transistor and fabrication method thereof
A method of forming a buried bit line is provided. A substrate is provided and a line-shaped trench region is defined in the substrate. A line-shaped trench is formed in the line-shaped trench region of the substrate. The line-shaped trench includes a sidewall surface and a bottom surface. Then, the bottom surface of the line-shaped trench is widened to form a curved bottom surface. Next, a doping area is formed in the substrate adjacent to the curved bottom surface. Lastly, a buried conductive layer is formed on the doping area such that the doping area and the buried conductive layer together constitute the buried bit line.
US08865547B2 Methods of fabricating a semiconductor device including fine patterns
Methods of fabricating a semiconductor device are provided. The method includes forming active lines in a semiconductor substrate, forming contact lines generally crossing over the active lines, forming line-shaped etch mask patterns generally crossing over the active lines and the contact lines, etching the contact lines exposed by the line-shaped etch mask patterns to form contact separation grooves and to form contact patterns generally remaining at intersections between the line-shaped etch mask patterns and the active lines, etching the active lines exposed by the contact separation grooves to form active separation grooves that generally divide each of the active lines into a plurality of active patterns, forming gates that substantially intersect the active patterns, and forming bit lines electrically connected to the contact patterns.
US08865544B2 Methods of forming capacitors
Some embodiments include a method of forming a capacitor. An opening is formed through a silicon-containing mass to a base, and sidewalls of the opening are lined with protective material. A first capacitor electrode is formed within the opening and has sidewalls along the protective material. At least some of the silicon-containing mass is removed with an etch. The protective material protects the first capacitor electrode from being removed by the etch. A second capacitor electrode is formed along the sidewalls of the first capacitor electrode, and is spaced from the first capacitor electrode by capacitor dielectric. Some embodiments include multi-material structures having one or more of aluminum nitride, molybdenum nitride, niobium nitride, niobium oxide, silicon dioxide, tantalum nitride and tantalum oxide. Some embodiments include semiconductor constructions.
US08865537B2 Differential excitation of ports to control chip-mode mediated crosstalk
A differential port and a method of arranging the differential port are described. The method includes arranging a first electrode to receive a drive signal, and arranging a second electrode to receive a guard signal, the guard signal having a different phase than the drive signal and the first electrode and the second electrode having a gap therebetween. The method also includes disposing a signal line from the first electrode to drive a radio frequency (RF) device.
US08865532B2 Active device array substrate and manufacturing method thereof
A method for manufacturing an active device array substrate includes providing a flexible substrate having a transistor region and a transparent region; forming a gate electrode on the transistor region; sequentially forming a dielectric layer and a semiconductor layer to cover the gate electrode and the flexible substrate; removing a part of the semiconductor layer to form a channel layer above the gate electrode and removing a thickness of the dielectric layer disposed on the transparent region, such that a portion of the dielectric layer on the gate electrode has a first thickness, and another portion of the dielectric layer on the transparent region has a second thickness less than the first thickness; respectively forming a source electrode and a drain electrode on opposite sides of the channel layer; and forming a pixel electrode electrically connected to the drain electrode.
US08865530B2 Extremely thin semiconductor on insulator (ETSOI) logic and memory hybrid chip
A method of forming a semiconductor device that includes providing a logic device on a semiconductor on insulating layer of a transfer substrate. The transfer substrate may further include a dielectric layer and a first handle substrate. A second handle substrate may be contacted to the semiconductor on insulating layer of the transfer substrate that includes logic device. The first handle substrate may be removed to expose the dielectric layer. A memory device can then be formed on the dielectric layer. Interconnect wiring can then be formed connecting the logic device with the memory device.
US08865529B2 Thin-film transistor device manufacturing method, thin-film transistor device, and display device
A thin-film transistor device manufacturing method and others according to the present disclosure includes: forming a plurality of gate electrodes above a substrate; forming a gate insulating layer on the plurality of gate electrodes; forming an amorphous silicon layer on the gate insulating layer; forming a buffer layer and a light absorbing layer above the amorphous silicon layer; forming a crystalline silicon layer by crystallizing the amorphous silicon layer with heat generated by heating the light absorbing layer using a red or near infrared laser beam; and forming a source electrode and a drain electrode on the crystalline silicon layer in a region that corresponds to each of the plurality of gate electrodes, and film thicknesses of the gate insulating layer, the amorphous silicon layer, the buffer layer, and the light absorbing layer satisfy predetermined expressions.
US08865522B2 Method for manufacturing semiconductor devices having a glass substrate
A method for connecting a semiconductor chip to a metal layer of a carrier substrate is disclosed. A semiconductor chip is provided which has a first side, a second side opposite the first side, a glass substrate bonded to the second side of the semiconductor chip and including at least one opening leaving an area of the second side of the semiconductor chip uncovered by the glass substrate, and a metallization region arranged in the opening of the glass substrate and electrically contacting the second side of the semiconductor chip. The semiconductor chip with the bonded glass substrate is brought onto a metal layer of a carrier substrate. A firm mechanical and electrical connection is formed between the metal layer of the carrier substrate and the metallization region.
US08865521B2 3D semiconductor package interposer with die cavity
A 3D semiconductor package using an interposer is provided. In an embodiment, an interposer is provided having a first die electrically coupled to a first side of the interposer and a second die electrically coupled to a second side of the interposer. The interposer is electrically coupled to an underlying substrate, such as a packaging substrate, a high-density interconnect, a printed circuit board, or the like. The substrate has a cavity such that the second die is positioned within the cavity. The use of a cavity may allow smaller conductive bumps to be used, thereby allowing a higher number of conductive bumps to be used. A heat sink may be placed within the cavity to aid in the dissipation of the heat from the second die.
US08865520B2 Carrier bonding and detaching processes for a semiconductor wafer
The present invention provides a temporary carrier bonding and detaching process. A first surface of a semiconductor wafer is mounted on a first carrier by a first adhesive layer, and a first isolation coating disposed between the first adhesive layer and the first carrier. Then, a second carrier is mounted on the second surface of the semiconductor wafer. The first carrier is detached. Then, the first surface of the semiconductor wafer is mounted on a film frame. The second carrier is detached. The method of the present invention utilizes the second carrier to support and protect the semiconductor wafer, after which the first carrier is detached. Therefore, the semiconductor wafer will not be damaged or broken, thereby improving the yield rate of the semiconductor process. Furthermore, the simplicity of the detaching method for the first carrier allows for improvement in efficiency of the semiconductor process.
US08865519B2 Method of manufacturing silicon carbide structure
A method of manufacturing a silicon carbide structure includes forming a silicon carbide layer by depositing silicon carbide on a base plate by chemical vapor deposition, removing the base plate, decreasing electrical conductivity by heat-treating the silicon carbide structure, and removing a thickness of 200 μm from an upper surface and a lower surface of the silicon carbide structure. In the present invention, silicon carbide is deposited by a CVD method, and the electrical conductivity of the silicon carbide is reduced to the electrical conductivity required for a protection ring of a plasma device through a post-treatment and a post-process. The electrical conductivity may be adjusted even without using separate additives.
US08865515B2 Preparation method for reduced graphene oxide using sulfonyl hydrazide-based reducing agent and optoelectronic devices thereof
A method for fabricating a graphene thin film by reducing graphene oxide and a method for fabricating an optoelectronic device using the same are provided. The method for fabricating a graphene thin film includes preparing graphene oxide; preparing graphene through reducing the graphene oxide by a sulfonyl hydrazide-based reducing agent; preparing a graphene dispersed solution by dispersing the graphene into an organic solvent; and fabricating a graphene thin film by applying the graphene dispersed solution. The sulfonyl hydrazide-based reducing agent may be a compound having a sulfonyl hydrazide substituent of Chemical Formula 1 in the present disclosure in which A may be any one in Chemical Formula 2 in the present disclosure.
US08865514B2 Post deposition adjustment of chalcogenide composition in chalcogenide containing semiconductors
The concentration of a constituent within a chalcogenide film used to form a chalcogenide containing semiconductor may be adjusted post deposition by reacting the chalcogenide film with a material in contact with the chalcogenide film. For example, a chalcogenide film containing tellurium may be coated with a titanium layer. Upon the application of heat, the titanium may react with the tellurium to a controlled extent to reduce the concentration of tellurium in the chalcogenide film.
US08865511B2 Semiconductor device and method for manufacturing the same
It is an object of the present invention to provide a technique in which a high-performance and high reliable memory device and a semiconductor device provided with the memory device are manufactured at low cost with high yield. The semiconductor device includes an organic compound layer including an insulator over a first conductive layer and a second conductive layer over the organic compound layer including an insulator. Further, the semiconductor device is manufactured by forming a first conductive layer, discharging a composition of an insulator and an organic compound over the first conductive layer to form an organic compound layer including an insulator, and forming a second conductive layer over the organic compound layer including an insulator.
US08865507B2 Integrated visible and infrared imager devices and associated methods
Semiconductor devices having three dimensional (3D) architectures and methods form making such devices are provided. In one aspect, for example, a method for making a semiconductor device can include forming a device layer on a front side of a semiconductor layer that is substantially defect free, bonding a carrier substrate to the device layer, processing the semiconductor layer on a back side opposite the device layer to form a processed surface, and bonding a smart substrate to the processed surface. In some aspects, the method can also include removing the carrier substrate from the semiconductor layer to expose the device layer.
US08865505B2 Diaphragm sheet, method for manufacturing solar cell module using diaphragm sheet, and lamination method using laminator for solar cell module manufacture
The performances and durability of a diaphragm sheet of a solar cell laminator are enhanced, and a favorable lamination work is stably performed over a long period of time. In addition, by stably performing sufficient and uniform lamination over a long period of time, a high-quality module is stably manufactured over a long period of time.A solar cell module is manufactured by using a diaphragm sheet formed of a composition containing an ethylene-propylene-diene rubber (EPDM), which is low in creep deformation and high in durability against an organic peroxide and a silane coupling agent.
US08865502B2 Solar cells with plated back side surface field and back side electrical contact and method of fabricating same
The present disclosure provides a method of forming a back side surface field of a solar cell without utilizing screen printing. The method includes first forming a p-type dopant layer directly on the back side surface of the semiconductor substrate that includes a p/n junction utilizing an electrodeposition method. The p/n junction is defined as the interface that is formed between an n-type semiconductor portion of the substrate and an underlying p-type semiconductor portion of the substrate. The plated structure is then annealed to from a P++ back side surface field layer directly on the back side surface of the semiconductor substrate. Optionally, a metallic film can be electrodeposited on an exposed surface of the P++ back side surface layer.
US08865501B2 Method of fabricating thermoelectric material and thermoelectric material fabricated thereby
The object of the present invention is to provide a method of fabricating a thermoelectric material and a thermoelectric material fabricated thereby. According to the present invention, since carbon nanotubes with no surface treatment are dispersed in the alloy, electrical resistivity decreases and electrical conductivity increases in comparison to surface-treated carbon nanotubes and an amount of thermal conductivity decreased is the same as that in the case of using surface-treated carbon nanotubes, and thus, a ZT value, a thermoelectric figure of merit, is improved. A separate reducing agent is not used and an organic solvent having reducing powder is used to improve economic factors related to material costs and process steps, and carbon nanotubes may be dispersed in the thermoelectric material without mechanical milling.
US08865498B2 Method for manufacturing three-dimensionally shaped comb-tooth electret electrode
A method for manufacturing a three-dimensionally shaped comb-tooth electret electrode, provided with positive ions, includes: forming a three-dimensional movable comb-tooth electrode and a three-dimensional fixed comb-tooth electrode from an Si substrate; contacting a vapor including ions thereto, and forming an oxide layer including ions upon surfaces of the comb-tooth electrodes with heat applied thereto; and applying a voltage between the movable electrode and the fixed electrode with heat applied thereto, and thereby causing the ions included in the oxide layer to shift to a surface of the oxide layer; wherein, the voltage between the movable electrode and the fixed electrode is changed, so that the operation of each of the comb-teeth of the movable electrode being alternatingly pulled in against two opposed comb-teeth of the fixed electrode is repeated, and the pulling in voltage and the pulled-in state release voltage are gradually increased.
US08865497B2 Planar cavity MEMS and related structures, methods of manufacture and design structures
A method of forming at least one Micro-Electro-Mechanical System (MEMS) includes forming a lower wiring layer on a substrate. The method further includes forming a plurality of discrete wires from the lower wiring layer. The method further includes forming an electrode beam over the plurality of discrete wires. The at least one of the forming of the electrode beam and the plurality of discrete wires are formed with a layout which minimizes hillocks and triple points in subsequent silicon deposition.
US08865495B2 Solid state lighting devices grown on semi-polar facets and associated methods of manufacturing
Solid state lighting devices grown on semi-polar facets and associated methods of manufacturing are disclosed herein. In one embodiment, a solid state light device includes a light emitting diode with an N-type gallium nitride (“GaN”) material, a P-type GaN material spaced apart from the N-type GaN material, and an indium gallium nitride (“InGaN”)/GaN multi quantum well (“MQW”) active region directly between the N-type GaN material and the P-type GaN material. At least one of the N-type GaN, InGaN/GaN MQW, and P-type GaN materials is grown a semi-polar sidewall.
US08865494B2 Manufacturing method for compound semiconductor light-emitting element
A compound semiconductor light-emitting element characterized by high transmittance of an electrically conductive film, low contact resistance and low sheet resistance of electrically conductive film is manufactured. The manufacturing method for a compound semiconductor light-emitting element of the present invention includes the steps of: forming a semiconductor layer formed of a group III nitride semiconductor, including a light-emitting layer on a substrate; forming an electrically conductive film on the side of the semiconductor layer opposite to the side contacting the substrate; conducting first annealing on the electrically conductive film in an atmosphere containing oxygen; conducting second annealing on the electrically conductive film in an atmosphere not containing oxygen; and exposing the electrically conductive film to atmospheric air between the step of conducting first annealing and the step of conducting second annealing.
US08865490B2 Method for producing light-emitting diode device
A method for producing a light-emitting diode device includes a step of preparing a sealing layer by sealing in a light-emitting diode with a sealing material; a step of preparing a fluorescent layer by allowing a phosphor-containing resin composition containing phosphor and silicone resin to reach its B-stage; and a step of bonding the fluorescent layer to the surface of the sealing layer.
US08865486B2 Organic light emitting display device and method for fabricating the same
The present application relates to a method for fabricating an organic light emitting display device, comprising: forming a drive thin film transistor on a substrate at a non-light emission region; forming a protective layer on the substrate; forming a color filter on the protective layer; forming a planarizing layer on a protective layer including the color filter; selectively removing the protective layer and the light compensating layer to form a first drain contact hole which exposes a drain electrode of the drive thin film transistor; forming a light compensating layer on the planarizing layer to have a second drain contact hole which exposes the first contact hole, and a dummy hole to expose the planarizing layer; and forming an organic light emitting element on the light compensating layer to be in contact with the drain electrode through the first and second drain contact holes.
US08865484B2 Methods for forming templated materials
Methods of forming layers can comprise defining a plurality of discrete site-isolated regions (SIRs) on a substrate, forming a first layer on one of the discrete SIRs, forming a second layer on the first layer, measuring a lattice parameter or an electrical property of the second layer, The process parameters for the formation of the first layer are varied in a combinatorial manner between different discrete SIRs to explore the possible layers that can result in suitable lattice matching for second layer of a desired crystalline structure.
US08865478B2 Reagents, kits and methods for detecting biological molecules by energy transfer from an activated chemiluminescent substrate to an energy acceptor dye
Reagents, kits and methods for detecting biological molecules by energy transfer from an activated chemiluminescent substrate to an energy acceptor dye such as a J-aggregated dye are described.
US08865471B2 Method for analyzing metal material
A method for analyzing a metal material includes electrolyzing a metal sample in an electrolytic solution, immersing a remaining portion of the metal sample taken out of the electrolytic solution in a dispersible solution to separate at least one substance selected from the group consisting of precipitates and inclusions attached to the remaining portion of the metal sample, filtering the dispersible solution containing the at least one separated substance through filters having straight pores and a porosity of 4% or more to obtain residues trapped on the filters and filtrates, and analyzing at least one of the residues and the filtrates.
US08865466B2 Nanotopographic compositions and methods for cellular organization in tissue engineered structures
The present invention relates to tissue engineered compositions and methods comprising nanotopographic surface topography (“nanotopography”) for use in modulating the organization and/or function of multiple cell types.
US08865462B2 Sustained culture of avian gonocytes
A sustained culture of isolated avian gonocytes is provided, as well as a method of making and using the same. A chimeric avian containing an isolated gonocyte and a transgenic avian produced using the chimeric avian are also provided. The cell and method may be employed to make, among other things, transgenic avian that produce a heterologous protein, e.g., a therapeutic protein.
US08865461B2 Rabies virus vector systems and compositions and methods thereof
Rabies Virus compositions and methods are provided. The full-length sequence of Rabies Virus strain Evelyn-Rokitnicki-Abelseth (ERA) is disclosed. A reverse genetics system for producing recombinant ERA virus and derivatives thereof is provided, along with compositions including ERA and/or ERA derivative strain viruses, nucleic acids and/or proteins. In some instances, the compositions are immunogenic compositions useful for the pre- or post-exposure treatment of Rabies Virus.
US08865458B2 Specimen collection and assay container
The present invention includes but is not limited to a specimen collection device that includes a chamber capable of collecting a specimen, a specimen passage slot, a reservoir, a reservoir seal, and a test device. A sample or specimen added to the chamber flows through the specimen passage slot into the reservoir. Flow into the reservoir may be limited by the reservoir seal. The test device positioned within the reservoir detects the presence or concentration of an analyte within the sample or specimen.
US08865457B2 Active, micro-well thermal control subsystem
Devices and systems for active thermal control of sample holding devices for bDNA testing, polymerase chain reaction testing, chemiluminescent immuno-assay testing, and so forth. The thermal control subsystem includes a fluidic circuit, first and second heater assemblies, a centrifugal pump, and a heat exchange device. The first and second heater assemblies include a heat removal device and a controllable thermo-electric device. One or both of the heater assemblies can include a heat spreader. A controller actively controls the pump, the heat removal device, and the thermo-electric devices, to thermally-control sample-containing vessels retained in the holding device.
US08865455B2 Apparatus and method
An apparatus for investigating a molecule comprising a channel provided in a substrate, a metallic moiety capable of plasmon resonance which is associated with the channel in a position suitable for the electromagnetic field produced by the metallic moiety to interact with a molecule passing therethrough, means to induce a molecule to pass through the channel, means to induce surface plasmon resonance in the metallic moiety; and means to detect interaction between the electromagnetic field produced by the metallic moiety and a molecule passing through the channel. Methods of investigating molecules are also provided.
US08865453B2 Landfill biofiltration system and methods for removal of gas-phase pollutants and contaminants
Biochemical decomposition of undesirable gaseous contaminants, including nitrogen oxides, VOC's, carbon monoxide and sulfur oxides, and malodorous contaminants, is achieved by passing a gas stream through a managed landfill providing microbiological activity capable of degrading the contaminants. Gases suitable for treatment include fuel combustor exhaust, landfill gases, putrescent gases and the like. The landfill functions as a biological reactor (bioreactor), where water is added if or as necessary to achieve concentrations between about 20% and about 65% by weight, and desired microbial contaminant abatement action. By a permeation of the polluted gas through the landfill, there is a consumption of polluting gases by microorganisms present in the landfill. The process enables increased combustion of fuels, such as landfill gases, whose energy values are currently wasted or are not available due to emissions problems. The excess oxygen normally present in exhaust can advantageously result in additional oxidative waste consumption by microorganisms, yielding additional “air space” that is an economic bonus in extending landfill life and/or lessening landfill use.
US08865450B2 Method for producing continuous cell lines
The present invention relates to a method for production of continuous cell lines comprising providing living cells of an animal or a human, irradiating said cells with UV light, proliferating said cells and selecting multiplying cells as cells of a continuous cell line.
US08865448B2 Aspergillus containing beta-glucosidase, beta-glucosidases and nucleic acids encoding the same
A novel microorganism is provided named Aspergillus saccharolyticus. Further, beta-glucosidase enzymes encoded by said microorganism are provided, and the use thereof in the degradation of lignocellulosic material. Also, host organisms comprising the polypeptides of the invention and/or polynucleotides encoding these are provided. In addition, methods, compositions, and kit-of-parts are provided which comprise any component of the invention, and optionally any additional components.
US08865444B1 β-mannanase having improved enzymatic activity
A β-mannanase having increased enzymaic activity is disclosed. The β-mannanase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of Tyrosine at position 216 with Tryptophan.
US08865442B2 Production of isoprene under reduced oxygen inlet levels
This invention relates to methods for producing isoprene by culturing recombinant cells (e.g., cells engineered to produce isoprene) under reduced oxygen inlet levels.
US08865439B2 Microorganisms for the production of methacrylic acid
The invention provides a non-naturally occurring microbial organism having a 2-hydroxyisobutyric acid, 3-hydroxyisobutyric acid or methacrylic acid pathway. The microbial organism contains at least one exogenous nucleic acid encoding an enzyme in a 2-hydroxyisobutyric acid, 3-hydroxyisobutyric acid or methacrylic acid pathway. The invention additionally provides a method for producing 2-hydroxyisobutyric acid, 3-hydroxyisobutyric acid or methacrylic acid. The method can include culturing a 2-hydroxyisobutyric acid, 3-hydroxyisobutyric acid or methacrylic acid producing microbial organism expressing at least one exogenous nucleic acid encoding a 2-hydroxyisobutyric acid, 3-hydroxyisobutyric acid or methacrylic acid pathway enzyme in a sufficient amount and culturing under conditions and for a sufficient period of time to produce 2-hydroxyisobutyric acid, 3-hydroxyisobutyric acid or methacrylic acid.
US08865432B2 Method for preparing cellulose derivatives having solubility improved
Provided is a method for preparing a cellulose derivative having solubility improved and therefore having less undissolved floating portions when the derivative is added into water. More specifically, provided is a method for preparing a cellulose derivative, comprising a step of depolymerizing a cellulose derivative to produce a depolymerized cellulose derivative having a viscosity at 20° C. in a 2% by weight aqueous solution of the depolymerized cellulose derivative reduced by at least 10% compared with that of the cellulose derivative before the depolymerization so that the number of undissolved floating portions in the aqueous solution of the depolymerized cellulose derivative is decreased compared with that of the cellulose derivative before the depolymerization. Depolymerization is effected preferably by an acid, alkali or enzyme.
US08865431B2 Antigen binding domains
A process for the production of an antigen specific antigen binding domain using a transformed host containing an expressible DNA sequence encoding the antigen specific antigen binding domain, wherein the antigen specific antigen binding domain is derived from a variable region of the immunoglobulin isotype NAR found in fish.
US08865430B2 Fusion polypeptides capable of activating receptors
A fusion polypeptide comprising (A)x-M-(A′)y, wherein A and A′ are each polypeptides capable of binding a target receptor. The fusion polypeptides of the invention form multimeric proteins which activate the target receptor. A and A′ may be each be an antibody or fragment derived from an antibody specific for a target receptor, such as the same or different scFv fragments, and/or a ligand or ligand fragment or derivative capable of binding the target protein, M is a multimerizing component, and X and Y are independently a number between 1-10.
US08865420B2 Methods and compositions for risk stratification
The present invention provides an approach for the simultaneous determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of potentiators of cellular activation allows for characterization of such pathways and cell populations.
US08865416B2 Analyte sensors, methods for preparing and using such sensors, and methods of detecting analyte activity
Analyte sensors, methods for producing and using analyte sensors, methods of detecting and/or measuring analyte activity, detecting pH change, and/or, controlling the concentration of an analyte in a system, are disclosed. Embodiments of the analyte sensors according to the disclosure can provide an accurate and convenient method for characterizing analyte activity, detecting pH change, controlling the concentration of an analyte in a system, and the like, in both in vivo and in vitro environments, in particular in living cell imaging.
US08865410B2 Error detection in sequence tag directed subassemblies of short sequencing reads
The invention provides compositions and methods for preparing DNA sequencing libraries. In particular, the method relates to preparing DNA sequencing libraries from kilobase scale nucleic acids. The invention also provides methods for assembling short read sequencing data into longer contiguous sequences. The method is useful for various applications in genomics, including genome assembly, full length cDNA sequencing, metagenomics, and the analysis of repetitive sequences of assembled genomes.
US08865408B2 Signature for the diagnosis of cancer aggressiveness and genetic instability
The present invention relates to a method for diagnosing aggressiveness and/or genetic instability of a cancer in a patient from a cancer sample of the patient. The method includes measuring in vitro the expression level of the POLQ gene and the expression level of a control gene in the patient cancer sample, calculating an expression level ratio of the expression level of POLQ to the expression of the control gene in the patient cancer sample, comparing the expression level ratio to a corresponding threshold value, and diagnosing cancer aggressiveness and genetic instability if the POLQ expression level ratio is superior to a corresponding threshold value. Dedicated microarrays and kits are also described, as well as a method of selecting a suitable treatment.
US08865404B2 Methods for sequencing nucleic acid molecules
Methods and compositions for determining the nucleic acid sequence of polynucleotides that are at least 1500 nucleotides in length are provided.
US08865399B2 Phage-mediated bioluminescent detection of Yersinia pestis
The present disclosure relates to compositions, methods, systems and kits for the detection of microorganisms of the Yersinia species including Yersinia pestis. The disclosure relates to recombinant phage operable to infect a Yersinia microorganism, the phage comprising a detectable reporter. Detection systems of the disclosure may comprise a phage operable to infect a Yersinia microorganism, and may comprise a reporter nucleic acid expressible upon infection of a Yersinia microorganism by the phage. The system may be operable to detect the expression of the reporter. A detectable reporter may comprise any gene having bioluminescent, colorimetric and/or visual detectability. For example, a detectable reporter may comprise one or more luxAB genes detectable by emission, enhancement and/or change in spectrum of bioluminescent light. Live and infectious Yersinia microbes may be detected by the compositions, methods, systems and kits described herein.
US08865393B2 Printed circuit board and method of manufacturing the same
Disclosed herein are a printed circuit board and a method of manufacturing the same, including: forming a protective layer on which a cover film is stacked on a base substrate; exposing the protective layer on which the cover film is stacked to photosensitize the protective layer and photodegrade the cover film; and developing the photodegraded cover film and the photosensitized protective layer to form an opening exposing a pad unit of a circuit layer which is an outermost layer of the base substrate on the protective layer, whereby the productivity of the printed circuit board can be improved without performing a process of separating a cover film.
US08865390B2 Patterning process and resist composition
A negative pattern is formed by coating a resist composition comprising a polymer comprising recurring units of acid labile group-substituted vinyl alcohol and maleic anhydride and/or maleimide, an acid generator, and an organic solvent onto a substrate, prebaking, exposing to high-energy radiation, and developing in an organic solvent developer such that the unexposed region of resist film is dissolved away and the exposed region of resist film is not dissolved. In image formation via positive/negative reversal by organic solvent development, the resist film is characterized by a high dissolution contrast between the unexposed and exposed regions.
US08865387B2 Electrostatic image developing toner
The present invention relates to, in the toner including toner particles having a biding agent resin, colorings and a release agent, an electrostatic image developing toner, its composition, and a preparation method thereof. The electrostatic image developing toner is prepared by the method comprising: (1) preparing an inorganic dispersion medium; (2) dispersing/dissolving a polymerizable monomer mixture; (3) micronizing the liquid obtained in step (2) in the liquid obtained in step (1) with high shear force in order to create droplets; (4) performing radical polymerization of the micronized droplets obtained in step (3); (5) aggregating particles obtained in step (4); (6) fusing the aggregate obtained in step (5); (7) cleaning and drying the toner obtained by step (6); and (8) adding additives to impart electrification and fluidity to a toner obtained by step (7).
US08865384B2 Electrophotographic toner, developer, and image forming apparatus
An electrophotographic toner, including: a binder resin; a colorant; and an organically-modified layered inorganic mineral, wherein the binder resin contains 50% by mass or more of a crystalline resin relative to the binder resin, and the crystalline resin contains a resin having a sulfonic acid group, and wherein an amount of the sulfonic acid group is 0.1% by mass to 2.0% by mass relative to the resin having the sulfonic acid group.
US08865379B2 Marked straws and methods for marking straws
Generally, polymeric members and laser marking methods for producing visible marks on polymeric members, such as on thin and/or curved surfaces. The laser marking methods can include methods of laser marking straws with the step of matching laser source properties to the properties of straws being marked or with the step of laser marking straws having photochromic dyes.
US08865378B2 Photomask blank, photomask, and methods of manufacturing the same
A photomask blank is for use in manufacturing a photomask to be applied with exposure light having a wavelength of 200 nm or less. The photomask blank has a light-transmitting substrate and a light-shielding film formed thereon. The light-shielding film has a light-shielding layer containing a transition metal and silicon and a front-surface antireflection layer formed contiguously on the light-shielding layer and made of a material containing at least one of oxygen and nitrogen. The light-shielding film has a front-surface reflectance of a predetermined value or less for the exposure light and has a property capable of controlling the change width of the front-surface reflectance at the exposure wavelength to be within 2% when the thickness of the front-surface antireflection layer changes in the range of 2 nm. The material of the front-surface antireflection layer having a refractive index n and an extinction coefficient k capable of achieving such property is selected.
US08865376B2 EUVL process structure fabrication methods
Methods are provided for fabricating a process structure, such as a mask or mask blank. The methods include, for instance: providing a silicon substrate; forming a multi-layer, extreme ultra-violet lithography (EUVL) structure over the silicon substrate; subsequent to forming the multi-layer EUVL structure over the crystalline substrate, reducing a thickness of the silicon substrate; and attaching a low-thermal-expansion material (LTEM) substrate to one of the multi-layer EUVL structure, or the reduced silicon substrate. In one implementation, the silicon substrate is a silicon wafer with a substantially defect-free surface upon which the multi-layer EUVL structure is formed. The multi-layer EUVL structure may include multiple bi-layers of a first material and a second material, as well as a capping layer, and optionally, an absorber layer, where the absorber layer is patternable to facilitating forming a EUVL mask from the process structure.
US08865375B2 Halftone phase shift blank photomasks and halftone phase shift photomasks
Halftone phase shift photomasks are provided including a substrate configured to transmit light; a shift pattern on the substrate, the shift pattern including a pattern area on a center portion of the substrate and a blind area disposed on a periphery of the substrate, the shift pattern of the blind area having a greater thickness than a thickness that of the pattern area, and being configured to partially transmit the light; and a light shielding pattern formed on the shift pattern in the blind area and being configured to shield the light. Related methods are also provided herein.
US08865373B2 Cell for solid oxide fuel cell
[OBJECT] In an SOFC cell comprising a Cr-containing alloy or the like and an air electrode bonded together, the invention is to provide a cell capable of effectively restricting occurrence of Cr poisoning of the air electrode and capable also of effectively restricting occurrence of oxidation deterioration due to Cr depletion in the alloy or the like.[SOLUTION] In a cell for a solid oxide fuel cell (SOFC) comprising a Cr (chrome)-containing alloy or oxide and an air electrode bonded together, wherein on the surface of the alloy or oxide, there is formed a coating layer containing a spinel oxide comprised of a first mono metal oxide and a second mono metal oxide, the first mono metal oxide having an equilibrium dissociated oxygen partial pressure at 750° C. ranging from 1.83×10−20 to 3.44×10−13 atm., the second mono metal oxide having a lower equilibrium dissociated oxygen partial pressure at 750° C. than the first mono metal oxide.
US08865367B2 Gas decomposition component
Provided is a gas decomposition component that employs an electrochemical reaction and can have high treatment performance, in particular, an ammonia decomposition component. The gas decomposition component includes a MEA 7 including a solid electrolyte 1 and an anode 2 and a cathode 5 that are disposed so as to sandwich the solid electrolyte; Celmets 11s electrically connected to the anode 2; a heater 41 that heats the MEA; and an inlet 17 through which a gaseous fluid containing a gas is introduced into the MEA, an outlet 19 through which the gaseous fluid having passed through the MEA is discharged, and a passage P extending between the inlet and the outlet, wherein the Celmets 11s are discontinuously disposed along the passage P and, with respect to a middle position 15 of the passage, the length of the Celmets disposed is larger on the side of the outlet than on the side of the inlet.
US08865365B2 Connector and fuel cell
A connector is connected with a connector joint structure formed in separators in a fuel cell. The connector has: a connector casing; a terminal element that is provided in the connector casing and is configured to be in contact with an edge side of the separator and to be elastically deformed in an insertion direction of the connector that is orthogonal to a stacking direction of the separators, when the connector is connected with the connector joint structure; and an engagement element that is formed in the connector casing and is configured to engage with the connector joint structure and restrict motion of the connector in the insertion direction when the connector is connected with the connector joint structure.
US08865363B2 Fuel cell
A fuel cell is provided with a separator that supports an electrolyte/electrode assembly sandwiched therebetween. The separator is provided with: first and second fuel gas supply parts in the center of which fuel gas supply holes are formed; first and second cross-link parts connected to the first and second fuel gas supply parts; and first and second sandwiching support parts connected to the first and second cross-link parts. Each first sandwiching support part is provided with a set of fuel gas exhaust passages that discharge fuel gas that has gone through a fuel gas passage and been used. The cross-sectional areas of the fuel gas exhaust passages are larger on the downstream sides than on the upstream sides, in terms of the direction of fuel gas flow.
US08865358B2 Method for load following operation of fuel cell system
Disclosed method of load-following operation of fuel-cell system comprises pre-determining functions F=f(P) and P=f−1(F), wherein P is the electric output and F is the fuel flow-rate required to output P. If reformable flow-rate FRPM, (2) is performed. (1) If f(PD)≦FR, the output is set at PD, and the fuel flow-rate is set at f(PD); and if f(PD)>FR, the output is set at the maximum value of P lower than PD and computed using P=f−1(FR), and the fuel flow-rate is set at FR. (2) If f(PM)≦FR, the output is set at PM, and the fuel flow-rate is set at f(PM); and if f(PM)>FR, the output is set at the maximum value of P computed using P=f−1(FR), and fuel flow-rate is set at FR.
US08865357B2 Fuel cell system and motor vehicle equipped therewith
A fuel cell system (1), especially in a motor vehicle, is provided with at least one fuel cell (18) for generating electric current from anode gas and cathode gas, with at least one reformer (22) for generating anode gas from oxidant gas and fuel. At least one residual gas burner (26) is provided for burning anode waste gas with cathode waste gas. A recycling device (48) is provided for recycling burner waste gas to the reformer (22).
US08865353B2 Nonaqueous electrolyte and lithium cell using the same
A nonaqueous electrolytic solution of an electrolyte salt dissolved in a nonaqueous solvent, containing a hydantoin compound represented by the following general formula (I) in an amount of from 0.01 to 5% by mass of the nonaqueous electrolytic solution, and excellent in battery characteristics such as high-temperature storage property and cycle property. (In the formula, R1 and R2 each represent a methyl group or an ethyl group; R3 and R4 each represent a hydrogen atom, a methyl group or an ethyl group.)
US08865350B2 Nonaqueous electrolyte battery
A nonaqueous electrolyte battery is provided and includes a positive electrode, a negative electrode having a negative electrode active material layer containing a negative electrode active material, a separator disposed between the positive electrode and the negative electrode, and a non-fluid electrolyte. The non-fluid electrolyte contains an electrolyte salt, a nonaqueous solvent, an orthoester compound represented by the following formula (1), and at least one member selected from the group consisting of cyclic carbonate compounds represented by the following formula (2) to (5). A volume viscosity of the negative electrode active material layer is 1.50 g/cc or more and not more than 1.75 g/cc, and a specific surface area of the negative electrode active material is 0.8 m2/g or more and not more than 4.0 m2/g
US08865349B2 Method of producing positive electrode active material and nonaqueous electrolyte battery using the same
The present invention provides a positive electrode active material that has rate characteristics suitable for nonaqueous electrolyte batteries and particularly nonaqueous electrolyte secondary batteries, a method by which this positive electrode active material can be easily mass produced, and a high-performance nonaqueous electrolyte battery that has a positive electrode active material obtained by this method.The present invention relates to a method of producing a positive electrode active material, the method comprising a step of mixing a carbon source with lithium manganese phosphate LiMnPO4 or a compound LiMn1-xMxPO4 (where, 0≦x<1 and M is at least one metal element selected from the group consisting of Co, Ni, Fe, Zn, Cu, Ti, Sn, Zr, V, and Al) containing lithium manganese phosphate LiMnPO4 as a solid solution composition, and heat treating the obtained mixture under an inert gas atmosphere.
US08865348B2 Positive active material comprising a continuous concentration gradient of a metal composition for lithium battery, method of preparing the same, and lithium battery including the same
A positive active material according to one embodiment of the present invention includes an internal bulk part and an external bulk part surrounding the internal bulk part and has a continuous concentration gradient of the metal composition from an interface between the internal bulk part and the external bulk part to the surface of the active material. The provided positive active material in which the metal composition is distributed in a continuous concentration gradient has excellent electrochemical characteristics such as a cycle life, capacity, and thermal stability.
US08865346B2 Cathode electrode and lithium ion battery
A cathode electrode of a lithium ion battery includes a cathode current collector and a cathode material layer. The cathode material layer is located on a surface of the cathode current collector. The cathode material layer includes a cathode active material. The cathode active material includes sulfur grafted poly(pyridinopyridine). The sulfur grafted poly(pyridinopyridine) includes a poly(pyridinopyridine) matrix and sulfur dispersed in the poly(pyridinopyridine) matrix. The cathode current collector includes a polymer substrate and a graphene layer located on a surface of the polymer substrate adjacent to the cathode material layer. A lithium ion battery using the cathode electrode is also disclosed.
US08865342B2 Polycarbonate resin composition and molded article
Provided a polycarbonate resin composition excellent in flame resistance, impact resistance, and color fastness. A polycarbonate resin composition containing, per 100 parts by mass of polycarbonate resin (A), 0.001 to 30 parts by mass of flame retardant (B), 0.001 to 1 part by mass of fluoropolymer (C), and 0.5 to 10 parts by mass of graft copolymer (D) obtainable by graft-copolymerizing a diene-based rubber with a (meth)acrylate ester compound, the graft copolymer (D) having (i) a sulfur content of 100 to 1500 ppm, and (ii) an average particle size of 70 to 240 nm.
US08865338B2 Battery module and battery device
A battery module includes: a plurality of battery cells; a casing in which the plurality of battery cells are housed; a plurality of conductive members that electrically connect the plurality of battery cells; and a voltage detection conductor that detects voltages at each of the plurality of battery cells. The casing includes at least a pair of resin side plates that sandwich and support the plurality of battery cells from both sides. The voltage detection conductor is formed in a predetermined shape and integrated with the side plates.
US08865329B2 Secondary battery pack of novel structure
Disclosed herein is a secondary battery pack including a battery cell including first and second electrode terminals of specific structures, a protection circuit module (PCM) including connection members A and B connected to the first and second electrode terminals and an electrically insulated top cap, wherein a connection portion of the connection member B connected to the second electrode terminal of the battery cell is located at the bottom of the PCB so that the connection member B is electrically connected to the second electrode terminal via the safety element, the connection member A is coupled to the bottom of the PCB in a state in which the connection member A protrudes from one end of the PCB in the lateral direction so that a connection portion of the connection member A connected to the first electrode terminal of the battery cell is exposed through a corresponding one of the through holes formed at the top cap, a coupling hole is formed at the protruding portion of the connection member A, and wherein coupling members are coupled into the respective coupling grooves of the battery cell through the through holes of the top cap in a state in which the PCM and the top cap are disposed at the top of the battery cell, and the connection member A is mechanically coupled and electrically connected to the first electrode terminal by a corresponding one of the coupling members.
US08865327B2 Perpendicular magnetic disc
A perpendicular magnetic disk that includes, on a base, a soft magnetic layer, an amorphous alloy layer, a preliminary ground layer provided on the amorphous alloy layer, a ground layer formed of Ru or a Ru-type alloy having an hcp crystal structure provided on the preliminary ground layer. A granular magnetic layer is provided on the ground layer. The amorphous alloy layer contains Ta, and the preliminary ground layer includes a first preliminary ground layer formed of Ti or a Ti alloy of microcrystals and a second preliminary ground layer formed of a Ni-type alloy of an fcc crystal structure.
US08865323B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same
A biscarbazole derivative of the invention is represented by a formula (1) below. In the formula (1): A1 represents a substituted or unsubstituted nitrogen-containing heterocyclic group having 1 to 30 ring carbon atoms; A2 represents a substituted or unsubstituted aromatic hydrocarbon group having 6 to 30 ring carbon atoms, or substituted or unsubstituted nitrogen-containing heterocyclic group having 1 to 30 ring carbon atoms; X1 and X2 each are a linking group; Y1 to Y4 each represent a substituent; p and q represent an integer of 1 to 4; and r and s represent an integer of 1 to 3.
US08865322B2 Dendrimer and organic light-emitting device using the same
A dendrimer and an organic light-emitting device including an organic layer having the dendrimer.
US08865317B2 Decorative laminate and method for manufacturing same
A decorative laminate includes a decorative layer and a core layer. The decorative layer is composed of a resin impregnated decorative sheet. The core layer is composed of at least one resin impregnated sheet of core paper. The core paper is impregnated with a resin composed of phenol formaldehyde resin and wood molasses. In this manner, a substantial portion of the resin used to impregnate the core paper is replaced with wood molasses, which results in a reduction of the cost of manufacturing the decorative laminate. The decorative laminate is manufactured by preparing a resin impregnated decorative sheet and preparing at least one resin impregnated core sheet by impregnating a core sheet with a resin composition composed of phenol formaldehyde resin and wood molasses. The decorative sheet and the core sheet are then layered to form a laminate lay-up that is heated and pressed to consolidate and cure the laminate.
US08865316B2 Rubber laminate
A rubber laminate comprises a reinforcing layer and a second rubber layer laminated sequentially on a first rubber layer, at least one outer surface of the first rubber layer and the second rubber layer being covered with an ultra high molecular weight polyethylene layer, wherein the rubber layers covered with the ultra high molecular weight polyethylene layer are formed from a rubber composition comprising from 20 to 40 parts by mass of a softener per 100 parts by mass of a mixed rubber consisting of from 60 to 80% by mass ratio of a diene rubber and 20 to 40% by mass ratio of a ethylene-propylene-diene rubber and/or a butyl rubber.
US08865312B2 Coating composition for solar cell backsheet and solar cell backsheet
A coating composition for a solar cell backsheet of the present invention includes: (a) 10 to 40 mass % of vinyl ester resin or unsaturated polyester resin; (b) 30 to 60 mass % of vinyl monomer and/or (meth)acrylate monomer; (c) 5 to 40 mass % of denaturant (The components (a) to (c) are 100 mass % in total); (d) 0.1 to 15 parts by mass of an ultraviolet curing agent relative to 100 parts by mass in total of the components (a) to (c); and (e) 5 to 20 parts by mass of a white colorant relative to 100 parts by mass in total of the components (a) to (c).
US08865311B2 Resin composition, prepreg, and laminate
A resin composition used to prepare a sheet-like prepreg by impregnating a substrate with the resin composition includes an epoxy resin that contains a naphthalene-modified epoxy resin, and a triazine-modified novolac resin. A sheet-like prepreg is formed by impregnating a substrate with the resin composition. A laminate formed using the prepreg exhibits excellent flame retardancy, solder heat resistance, and lead-free heat resistance, has a small coefficient of linear expansion in the thickness direction, and has excellent adhesion to a conductor circuit.
US08865310B2 Polymer systems with multiple shape memory effect
A polymer material system that consists of multiple SMP layers of different shape memory transition temperatures in a multilayer construction to achieve and tailor a multiple shape memory effect. Wherein two SMP layers of different shape memory transition temperatures are utilized, a triple shape memory effect is achieved.
US08865306B2 Intermediate transfer members containing fluorinated polyamic acids
An intermediate transfer member that includes a fluorinated polyamic acid and a conductive component.
US08865298B2 Article with metal grid composite and methods of preparing
A laminate donor element can be used to transfer a composite of a metal grid and an electronically conductive polymer to a receiver sheet for use in various devices. The laminate donor element has a donor substrate, a metal grid that is disposed over only portions of the donor substrate, leaving portions of the substrate uncovered by the metal grid, and an electronically conductive polymer that covers the portions of the donor substrate that are uncovered by the metal grid. The composite of metal grid and electronically conductive polymer exhibits a peel force of less than or equal to 40 g/cm for separation from the donor substrate at room temperature. The resulting article has a substrate on which a reverse composite of the metal grid and electronically conductive polymer is disposed, which article can be incorporated into various devices.
US08865296B2 Designed defects in laminate composites
Novel methods and kits for creating defects in composite materials, as well as an engineered part or structure with one or more designed defects, are disclosed. The disclosed inventions advantageously permit the intentional introduction of one or multiple defects of any desired size and shape, either between the same two chosen laminae or on different layers within a multi-layer composite, having mechanical and thermal properties that are akin to those found for actual defects. One disclosed method involves creating a mask having a cut-out in the size and shape of a desired defect, placing the mask at a location on a first substrate where the defect is desired, applying a release agent, removing the mask, and adding a second substrate over the first substrate with release agent. The first substrate may be a cured lamina or an uncured lamina pre-impregnated with resin having a barricade in the size and shape of the outline of the desired defect.
US08865293B2 Optically active materials and articles and systems in which they may be used
The inventors of the present application developed novel optically active materials, methods, and articles. One embodiment of the present application is an optically active article, comprising: an infrared-reflecting material positioned adjacent to an optically active substrate such that the infrared-reflecting material forms a pattern that can be read by an infrared sensor when the optically active substrate is illuminated by an infrared light source. Another embodiment of the present application relates to a method of manufacturing an optically active article, comprising: obtaining an optically active sheeting; and positioning an infrared-reflecting material on the optically active sheeting to form a pattern. The optically active article may be, for example, a license plate.
US08865287B2 Rapid curing aldehyde resin-polyisocyanate composition and method for producing hybrid polymer
A hybrid polymer composition and a method for forming it is provided, comprising a first part A comprising a polyurethane catalyst and an aldehyde resin pre-polymer and a second part B comprising a polyisocyanate pre-polymer and an aldehyde resin cure accelerator. Methods are also provided for forming a composite with a two part hybrid polymer composition and a fibrous web material.
US08865286B2 Optical information recording medium
An optical information recording medium includes: a substrate; two or more information signal layers provided on the substrate; and a cover layer provided on the information signal layers. At least one of the two or more information signal layers is provided with an inorganic recording layer including Pd oxide, a first protective layer provided on a first main surface of the inorganic recording layer, and a second protective layer provided on a second main surface of the inorganic recording layer. And at least one of the first protective layer and the second protective layer includes a compound oxide of Si oxide, In oxide and Zr oxide as a main component.
US08865279B2 Reinforced polyphthalamide/poly(phenylene ether) composition
Disclosed herein is a reinforced composition comprising: 55 to 80 wt % of a compatibilized blend of a polyphthalamide and a poly(phenylene ether) wherein said compatibilized blend is formed from a mixture of polyphthalamide and poly(phenylene ether) in a ratio of between 1.5:1 and 7.0:1, and a functionalizing agent in an amount sufficient to effect compatibilization; and 20 to 45 wt % of a nylon glass fiber, wherein the composition contains less than 0.1 wt % of phosphinates and less than 0.1 wt % of impact modifiers and weight percent is based on the total weight of the composition.
US08865278B2 Polymeric material for making a packaging article having oxygen-barrier properties and low light transmission properties
The polymeric material having oxygen barrier properties and low light transmission characteristics, in particular within the UV and visible light wavelengths and comprises (A) a polyester, (B) mineral particles, (C) a polyamide, and (D) at least one transition metal catalyst. Preferably the amount of mineral particles is not more than 26 wt % of the total weight of the material, and is not less than 20 wt % of the total weight of the material.
US08865277B2 Inkjet media
In one example, an inkjet media includes a substrate layer with cellulose fibers, synthetic fibers, and a polymeric binder. A barrier layer is disposed on at least one side of the substrate layer, the barrier layer including pigment fillers and at least 30 percent by weight of a polymer resin.
US08865276B2 Water-pressure transfer printing film
A water-pressure transfer printing film that achieves a smooth image surface on the transfer target by allowing print images such as photographs to be transferred without causing the image quality to degrade, wherein such water-pressure transfer printing film is characterized in that it has at least two layers including an ink-receiving layer and a base layer and that the base layer has a surface roughness Ra of 0.40 μm or less and gloss of 80 or more.
US08865271B2 High rate deposition for the formation of high quality optical coatings
High rate deposition methods comprise depositing a powder coating from a product flow. The product flow results from a chemical reaction within the flow. Some of the powder coatings consolidate under appropriate conditions into an optical coating. The substrate can have a first optical coating onto which the powder coating is placed. The resulting optical coating following consolidation can have a large index-of-refraction difference with the underlying first optical coating, high thickness and index-of-refraction uniformity across the substrate and high thickness and index-of-refraction uniformity between coatings formed on different substrates under equivalent conditions. In some embodiments, the deposition can result in a powder coating of at least about 100 nm in no more than about 30 minutes with a substrate having a surface area of at least about 25 square centimeters.
US08865266B2 Method of coating a porous substrate
The present invention relates to a method of coating a porous substrate. The method includes forming a first coating on the substrate that at least partially fills the pores of the substrate, forming a second coating on the substrate, and optionally at least partially restoring the porosity of the porous substrate.
US08865261B2 Extrusion coating of elongated substrates
The present disclosure relates to extrusion coating systems, extrusion coated substrates, and processes for making the same. In some aspects, extrusion coating systems as described herein may include an at least partially insulated outlet wall, which may facilitate production of coated substrates exhibiting a very desirable surface texture and appearance. Coated substrates of the present invention may be utilized in a variety of end applications, including, but not limited to, interior and exterior construction materials for homes, buildings, and furniture.
US08865260B2 Method of making a coated ceramic cutting insert
A coated ceramic cutting insert for removing material from a workpiece, as well as a method for making the same, that includes a ceramic substrate with a rake surface and at least one flank surface wherein a cutting edge is at the juncture therebetween. A wear-resistant coating scheme that includes an alumina-containing base coating layer region, which has at least one exposed alumina coating layer, deposited by chemical vapor deposition on the substantially all of the surfaces of the ceramic substrate that experience wear during removal of material from the workpiece. The exposed alumina coating layer exhibits a blasted stress condition ranging between about 50 MPa (tensile stress) and about −2 GPa (compressive) as measured by XRD using the Psi tilt method and the (024) reflection of alumina. The exposed alumina coating layer is the result of wet blasting a titanium-containing outer coating layer region from the surface of the alumina-containing base coating layer region.
US08865258B2 Method of manufacturing thin film which suppresses unnecessary scattering and deposition of a source material
The present invention provides a thin film manufacturing method which realizes stable, highly-efficient film formation using a nozzle-type evaporation source while avoiding unnecessary scattering and deposition of a film formation material after the termination of the film formation. Used is a film forming apparatus including: an evaporation chamber 16; a film forming chamber 17 in which a substrate 21 is provided; an evaporation source 19 holding a film formation material 15 and including an opening surface 14; a moving mechanism 35 configured to cause the evaporation source 19 to move; and a conductance variable structure 34. The film formation is performed in a state where the opening surface 14 of the evaporation source 19 holding the heated film formation material is located close to the substrate 21 while evacuating the evaporation chamber 16 and the film forming chamber 17 without shutting off communication between the evaporation chamber 16 and the film forming chamber 17 by the conductance variable structure 34. Next, the evaporation of the film formation material is suppressed by introducing a nonreactive gas to the evaporation chamber 16 and the film forming chamber 17 to adjust pressure in each chamber to predetermined pressure or more. Then, the evaporation source 19 is moved by the moving mechanism 35 such that the opening surface 14 is located away from the substrate 21. The conductance variable structure is activated to shut off the communication between these chambers, and the film formation material is cooled while continuously introducing the nonreactive gas to the evaporation chamber 16.
US08865255B2 Method for assessing the coolant consumption within actively cooled components
A process for setting the average flow rate within a hollow component is provided. The process includes setting a relatively small wall thickness in a first region with a relatively large flow cross section using a first diffusion coating process and setting a relatively large wall thickness by a second different diffusion process in a second region with a relatively small flow cross section. The use of different diffusion coatings in a component allows the flow of coolant through a component to be set in a controlled manner.
US08865254B2 Method for applying a material onto a substrate using a droplet printing technique
The invention provides a method for applying a material onto a substrate using a droplet printing technique, wherein the material is provided in the form of a solution of a precursor of the material or a suspension of the material, droplets are generated from the solution or the suspension and the droplets are heated before they are deposited on the substrate.
US08865250B2 Production of pulverulent coating compositions for stable protective coatings for pharmaceutical dosage forms
Described are processes for producing pulverulent coating compositions comprising providing an aqueous polymer dispersion comprising i) as component A a polymer obtained by radical polymerization of a) N,N-diethylaminoethyl methacrylate, and b) at least one radically polymerizable compound selected from esters of α,β-ethylenically unsaturated mono- and dicarboxylic acids with C1-C8-alkanols; and spray processing the aqueous polymer dispersion in the presence of a drying gas to provide a powder, wherein the entry temperature of the drying gas into the spraying apparatus is at least 20° C. above the glass transition temperature and is at least 20° C. above the minimum film-forming temperature of the polymer and the exit temperature of the drying gas from the spraying apparatus is kept at 40 to 85° C.
US08865249B2 Techniques to improve polyurethane membranes for implantable glucose sensors
The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.
US08865246B2 Oil or fat composition, chocolate and combined confectionery
Provided are: an oil or fat composition, which is capable of preventing the migration of oil or fat in a combined confectionery that comprises a combination of a chocolate with an oil or fat-based food material, has a good tolerance against cold blooming that is caused by the migration of oil or fat and softening of a chocolate, and enables the production of a chocolate having a high meltability in mouth; a chocolate using the oil or fat composition; and a combined confectionery using the chocolate.
US08865244B2 Pellet systems for preparing beverages
Methods, compositions, and articles of manufacture for preparing frozen beverages are described. The methods and articles generally include first and/or second frozen pellets. Upon mixing the frozen pellets with an appropriate liquid for a sufficient time, a frozen beverage is obtained. Articles of manufacture including frozen pellets, as well as optional objects such as straws, spoons, and mixing containers are disclosed. Methods, compositions, and articles of manufacture for preparing frozen pellets are also described.
US08865242B2 Cellulose composite
Disclosed is a cellulose composite which comprises cellulose and a hydrophilic gum, the cellulose composite giving a 1-mass % aqueous dispersion thereof which has a storage modulus (G′) of 0.06 Pa or more when the pH thereof is 4.
US08865240B2 Process for manufacturing chewable dosage forms for drug delivery and products thereof
A palatable, edible soft chewable medication vehicle for delivery of a pharmaceutically acceptable active ingredient, such as a drug, to an animal or human subject. The edible soft chews contain only food grade or better inactive ingredients, and preferably do not contain ingredients of animal origin. Processes for manufacturing the edible soft chews do not require the use of heat or the addition of water during mixing of active and inactive ingredients, provide stable concentrations of the active ingredient, and produce chews of consistent weight and texture.
US08865237B2 Method of preparing dialysed extract of fenugreek seeds which induces hypoglycemia, mediated, in part, via stimulation of insulin signaling pathway
A method of preparing dialysed aqueous extract of fenugreek seeds comprising washing the fenugreek seeds is distilled water, sterilizing the said seeds, subjecting the sterilized seeds to the step of grinding to form powder, suspending the said powder in phosphate buffered saline (PBS), subjecting the said suspension to the step of filtration to obtain the filtrate, treating the filtrate with activated charcoal to obtain clear supernatant, subjecting the supernatant to the step of lyophilization and the powder thus obtained was dissolved in phosphate buffered saline (PBS), dialyzing the aqueous extract of fenugreek seeds to obtain dialysed fenugreek seed extract (FSE) which was aliquoted and stored.
US08865236B2 Solvent-Free Process for Obtaining Phospholipids and Neutral Enriched Krill Oils
The invention discloses a new solvent-free process for obtaining phospholipids and neutral lipids enriched krill oils containing DHA and EPA poly-unsaturated fatty acids and astaxanthin. The process includes cooking fresh krill at high temperature—without agitation and or grinding; decanting the cooked krill for obtaining a partial de-fatted and de-watered solid and a liquid; squeezing the obtained solid to obtain a press liquid and a solid fraction; centrifuging the press liquid to obtain the phospholipids enriched krill oil; centrifuging of the decanter liquid obtained to obtain the neutral lipid enriched krill oil and stickwater.
US08865231B2 Hoya carnosa extracts and methods of use
Methods of using extracts of Hoya carnosa to impart anti-aging benefits to skin and/or improve skin conditions resulting from aging or damaged skin.
US08865230B2 Compositions and methods for treating parasitic infections
Compositions for treating parasitic infections and methods of using the compositions to treat subjects with parasitic infections are provided. Methods of selecting compositions for use in treating parasitic infections are further provided.
US08865226B2 Low foaming enhanced biocidal hydrogen peroxide composition
The present invention discloses a biocidal composition comprising hydrogen peroxide in a concentration of 0.05-50% (w/w) and a compound with a structure according to Formula 1: R—O—(CH(Y)—CH2—O)n—CH2—COOH, wherein R is an alkyl or alkenylene radical containing 6-12 carbon atoms, Y is H or CH3, and n is 3-10, in a concentration of 0.01-60% (w/w). An especially preferred compound according to Formula 1 is R is 6 or 8 and n is 3-8.
US08865222B2 Beta-casein assemblies for enrichment of food and beverages and methods of preparation thereof
The invention relates to a composition for the enrichment of food and/or beverage and to a method of preparing such composition. The composition comprises additive loaded beta-casein micelles which are of a diameter of about 100 nm or less. These nano-sized beta-casein assemblies are formed at pH values which are preferably one or more pH units above or below the pI of the protein (pI=5.3). More preferably the beta-casein nano-assemblies are formed at a pH range between about 6.0 and about 8, or between about 2.0 and about 4.2. The invention provides vehicles for delivery of additives via transparent beverages and other foods and drinks and/or acidic foods and drinks and/or non fat foods and drinks.
US08865221B2 Swellable and degradable microspheres
Swellable and degradable microspheres are described. The microspheres are prepared by a process that is reliable and high yielding, and makes use of a low temperature azo initiator, a small molecule chlorinated solvent as the organic phase, and a heat treatment step, and is carried out in absence of a crosslinking agent. The microsphere preparation made using the process is particularly useful as a degradable embolic material.
US08865219B2 Orodispersible tablets of bitter active principles
The invention concerns coated granules including (A) at least one amine-containing pharmacological active principle, preferably as an acid addition salt, the pharmacological active principle being complexed by low cation-exchange resin containing carboxylic acid groups (COO″), and (B) at least 15 wt. %, based on the total weight of the active principle/low cation-exchange resin complex, of at least one hydrophilic adsorbent, the mixture of the components (A) and (B) being coated with a gastrosoluble polymer. The invention also concerns a method for preparing such granules, as well as orodispesible tablets containing such granules.
US08865215B2 Matrix for tissue repair
Implants include a porous layer made from a composition including a compound wherein collagen is cross-linked to a glycosaminoglycan, the porous layer being optionally joined to a collagen film.
US08865212B2 Stable pharmaceutical formulation of an acid labile compound and process for preparing the same
The disclosed invention provides oral pharmaceutical formulations of an acid labile benzimidazole derivative comprising (a) a core comprising an acid labile benzimidazole derivative, (b) a seal coating layer, and (c) an enteric coating layer, wherein the core of the composition is devoid of any disintegrant.
US08865210B2 Stable dosage formulations of imidazolylalkyl-pyridines
Stable formulations of imidazolylalkyl-pyridines, including controlled-release formulations.
US08865209B1 Combined sublingual and gastro-intestinal delivery method of a liquid medication in a single volume limited dose
A method is disclosed for self-administered delivery of a pre-determined amount of liquid medication where a portion of the liquid medication is administered sublingually and the remaining portion is swallowed for and gastro-intestinal absorption.
US08865208B2 Vesicle useful for external preparation for skin, and external preparation for skin comprising the vesicle
Disclosed is a technique for allowing an active ingredient as an agent for improving or maintaining the dermal environment to reach a dermis. Specifically disclosed is a vesicle comprising the following components 1) to 3): 1) an α,ε-bis(γ-N—(C10-30)acylglutamyl)lysine and/or a salt thereof; 2) ceramide and/or a derivative thereof; and 3) one or more selected from a glycerin fatty acid ester, a polyglycerin fatty acid ester and a pyroglutamic acid glycerin fatty acid ester. The acyl group in the α,ε-bis(γ-N—(C10-30)acylglutamyl)lysine is preferably a lauroyl group. The ceramide or the derivative thereof is preferably ceramide type-2 or ceramide type-3. The vesicle can encapsulate an active ingredient. The vesicle can be contained in an external preparation for the skin.
US08865204B2 Manufacture of lozenge product with radiofrequency
The present invention features a process for making a lozenge product including the steps of forming a powder blend containing an amorphous carbohydrate polymer into the desired shape of the lozenge product and applying radiofrequency energy to the shape for a sufficient period of time to soften or melt said amorphous carbohydrate polymer to fuse the shape into said lozenge product.
US08865202B2 Water soluble film for oral administration with instant wettability
A composition containing therapeutic agents and/or breath freshening agents for use in the oral cavity is disclosed. The carrier comprises water-soluble polymers in combination with certain ingredients and provides a therapeutic and/or cosmetic effect. The film is coated and dried utilizing existing coating technology and exhibits instant wettability followed by rapid dissolution/disintegration upon administration in the oral cavity.
US08865184B2 Vaccine for chikungunya virus infection
The present invention relates to vaccine formulation capable of eliciting protective immune response against Chikungunya virus infection in humans and other mammalian hosts. The immunogenic formulation comprises purified inactivated Chikungunya virus in a stable formulation. Methods of propagation and purification of the virus are discussed. The inactivated virus formulation is non-infectious, immunogenic and elicits protective immune response in mammalian host. The immunogenic composition is formulated for in vivo administration to humans. The invention also discusses the strategy of developing a subunit vaccine using the recombinant viral proteins as antigens for immunization. The recombinant virus antigens that are potentially immunogenic can be used in diagnosing for the presence of the virus.
US08865183B2 Treatment of pigs with PCV2 antigent
The present invention relates to a method for the treatment or prophylaxis of a PCV2 infection or for reduction of clinical symptoms caused by or associated with a PCV2 infection in animals a) having anti-PCV2 antibodies and/or b) being young piglets of 1 to 22 days of age, comprising the step of administering an effective amount of a PCV2 antigen to that animal in need of such treatment. Preferably, those animals are pigs or young piglets.
US08865181B1 Extracting method of Antrodia cinnamomea
An extracting method of Antrodia cinnamomea, being apt to improve extraction rate of dehydrosulphurenic acid, comprises: soaking a sample of raw Antrodia cinnamomea in a salt solution, with the sample of raw Antrodia cinnamomea absorbing the salt solution, to obtain a soaked Antrodia cinnamomea; and further soaking the soaked Antrodia cinnamomea in an alcohol solvent, and obtaining an extract of Antrodia cinnamomea through sonication.
US08865174B2 Methods of treatment using human antibodies that bind IL-12
Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention.
US08865170B2 Anti-human CCR7 antibody, hybridoma, nucleic acid, vector, cell, pharmaceutical composition, and antibody-immobilized carrier
The present invention is novel anti-human-CC-motif-receptor-7 (anti-human-CCR7) antibodies useful for treating tissue fibrosis or cancer, and pharmaceutical compositions containing the anti-human-CCR7 antibodies. The invention includes an anti-human-CCR7 antibody specifically binding to an extracellular domain of human CCR7, having a heavy chain CDR3 containing an amino acid sequence represented by SEQ ID NO: 7, SEQ ID NO: 17, SEQ ID NO: 27, SEQ ID NO: 37, SEQ ID NO: 47, SEQ ID NO: 57, SEQ ID NO: 67, or SEQ ID NO: 77. The invention also includes an anti-human-CCR7 antibody having heavy chain CDRs 1-3 and light chain CDRs 1-3 containing amino acid sequences represented by SEQ ID NOs: 5-10, 15-20, 25-30, 35-40, 45-50, 55-60, 65-70, or 75-80. Preferably, the antibody has an activity of interfering with a CCR7-dependent intracellular signal transduction mechanism caused by CCR7 ligand stimulation.
US08865169B2 Methods and systems for multi-antibody therapies
The present invention relates to methods and systems for administering antibody therapeutic agents. The methods include administering one or more (e.g., two or three) binding agents, wherein each of the binding agents has a binding region that is specific to a portion of a disease agent and one or more copies of a tag. The binding agents can be specific to one or more portions of the same or different disease agents. The tag is the same for each of the binding agents. The methods include administering an anti-tag antibody, wherein the anti-tag antibody has an anti-tag region that is specific to the tag, and can have an immunoglobulin (e.g., IgA, IgD, IgE, IgG, and IgM.). Disease agents include bacterial proteins, viral proteins, cancer cells, and proteins or toxins produced therefrom. In particular, the present invention includes methods and systems for binding agents that are specific to neurotoxins that cause botulism.
US08865167B2 Neutralising antibody molecules having specificity for human IL-17
The invention relates to an antibody molecule having specificity for antigenic determinants of IL-17, therapeutic uses of the antibody molecule and methods for producing said antibody molecule.
US08865160B2 Treatment of disease conditions via administration of DNA repair enzyme
The present invention is directed to compositions and methods of preserving viability of islets of Langerhans for transplantation, and treating various diseases and other abnormal or pathological conditions, including inflammatory bowel disease, ischemic heart disease, acute lung injury, acute respiratory distress syndrome and radiation-induced brain injury, with DNA repair enzymes that are directed to the mitochondria.
US08865156B2 Compositions and methods for the maintenance of oral health
The invention provides compositions comprising one or more isolated LDH-deficient mutans streptococcus strains and one or more isolated S. oralis strains and/or one or more isolated S. uberis strains. Compositions of the invention are useful to maintain oral health, by for example treating and/or preventing one or more symptoms of dental caries, periodontitis and/or other oral cavity diseases or wounds.
US08865154B2 Recombinant factor VIII having enhanced stability following mutation at the A1-C2 domain interface
The invention relates to a recombinant factor VIII that includes one or more mutations at an interface of A1 and C2 domains of recombinant factor VIII. The one or more mutations include substitution of one or more amino acid residues with either a cysteine or an amino acid residue having a higher hydrophobicity. This results in enhanced stability of factor VIII. Methods for making the recombinant factor VIII, pharmaceutical compositions containing the recombinant factor VIII, and use of the recombinant factor VIII for treating hemophilia A are also disclosed.
US08865147B2 Hair cleansing and conditioning composition
The present invention comprises a composition for hair cleansing and conditioning, including at least one anionic surfactant, at least one cationic hair conditioning agent, and an acrylate-based polymer capable of thickening and stabilizing the composition, wherein the composition is essentially free of sulfate-based surfactant and silicone-based hair conditioning agent. In addition, the invention also comprises a method of cleansing and conditioning hair by providing a composition having at least one anionic surfactant, at least one cationic hair conditioning agent, and an acrylate-based polymer capable of thickening and stabilizing the composition, applying the composition to treat the hair of a user and rinsing the treated hair with sufficient amount of water.
US08865146B2 Hair styling method
A hair styling method, including the steps of: applying a hair cosmetic composition containing a component (A) to the hair: Component (A): an organopolysiloxane wherein at least two silicon atoms in organopolysiloxane segments which constitute the main chain of the organopolysiloxane (a) are bound to poly(N-acylalkyleneimine) segments (b) consisting of repeating units represented by the following general formula (1): via respective alkylene groups each containing a hetero atom, wherein the number-average molecular weight of the poly(N-acylalkyleneimine) segments is from 1,200 to 5,500, wherein the mass ratio of the component (a) to the component (b) [i.e., a/b] is from 35/65 to 60/40, wherein the weight-average molecular weights of the organopolysiloxane segments between adjacent two poly(N-acylalkyleneimine) segments (b) are from 1,300 to 5,500, and wherein the weight-average molecular weight of the organopolysiloxane segments (a) is from 7,000 to 100,000; forming the hair style at a hair temperature of 50° C. or higher; and subsequently cooling the hair temperature to lower than 50° C. to fix the formed hair style.
US08865140B2 Soap-based liquid wash formulations with enhanced deposition of make-up agents
The invention relates to soap based liquid body and facial wash compositions. Using high solvent, low water compositions and incompletely neutralized fatty acid to help structure the compositions, all in combination with modified benefit agents, enhanced deposition of make-up agents is achieved.
US08865135B2 Stable dentifrice compositions
A cationic-compatible inorganic particulate comprising silica substantially coated with a non-ionic surfactant, such as an ethoxylated hydrogenated hydrocarbon oil. Compositions comprising the cationic-compatible particulate and a cationic active, such as cetyl pyridinium chloride or an ethyl lauryl arginine ester, are also provided.
US08865133B2 Bi-Layer Pressed Powders Oral Adhering Tablet with Acacia gum adhesive
A bi-layer, oral adhering tablet (troche) made by pressing powders with a bi-layer tablet press, having greater than 80% acacia gum as an adhesive in an adhering layer. In a preferred embodiment, the tablet has about 99% acacia gum.
US08865129B2 Lanthanoid complex capsule and particle contrast agents, methods of making and using thereof
The invention relates to compositions of DOTA derivative compounds, lanthanoid-DOTA derivative molecular complex, and lanthanoid-complex encapsulated solid lipid particles or capsules, and methods of making and using the compositions. The solid lipid particles or capsules contain micelle cores stabilized by a hyperbranched polymer shell based from a crosslinked DOTA derivative compound or crosslinked lanthanoid-DOTA derivative complex. These solid lipid particles or capsules can be used in various applications, such as contrast agents or drug delivery vehicles.
US08865127B2 Simplified and improved method for preparing an antibody or an antibody fragment targeted immunoliposome for systemic administration of a therapeutic or diagnostic agent
Provided herein is an antibody- or antibody fragment-targeted cationic immunoliposome complex prepared by a method comprising the steps of (a) preparing an antibody or antibody fragment; (b) mixing the antibody or antibody fragment with a cationic liposome and to form a cationic immunoliposome wherein the antibody or antibody fragment is complexed with the cationic liposome, but is not chemically conjugated to the cationic liposome and wherein said antibody or antibody fragment does not comprise a lipid tag; and (c) mixing the cationic immunoliposome with a therapeutic or diagnostic agent to form the antibody- or antibody fragment-targeted cationic immunoliposome. Also provided is an antibody- or antibody fragment-targeted cationic immunoliposome comprising an antibody or antibody fragment; a cationic liposome, wherein the antibody or antibody fragment is complexed with the cationic liposome, but is not chemically conjugated to the cationic liposome and wherein said antibody or antibody fragment does not comprise a lipid tag and a therapeutic or diagnostic agent.
US08865124B2 Probe reagent for measuring oxidative stress
The present invention relates to fluorescent or luminescent probe reagents for measuring oxidative stress in a cell or an organism. Examples of the probe reagents include: a fluorescent or luminescent protein and a marker protein; a fluorescent or luminescent protein, a marker protein, and a regulatory factor; or a fluorescent or luminescent protein, a marker protein, a cleavage sequence, and a regulatory factor. In the probe reagents, the marker protein makes it possible to detect the oxidative stress caused by reactive oxygen species and comprises a regulatory factor-binding site and a ubiquitin-binding site; and the regulatory factor is a protein making it possible to regulate degradation of the marker protein in response to the reactive oxygen species. The present invention also relates to a method of measuring oxidative stress in a cell or an organism, or a method of screening a substance which suppresses or promotes the oxidative stress in a cell or an organism by using the probe reagent.
US08865118B2 Continuous hydrogen production device and method thereof
The present invention provides a continuous hydrogen production device and method thereof. The device comprises a reaction chamber, a solid raw material inlet, a liquid raw material inlet, a gas outlet, and a temperature controller. The reaction chamber contains an initiation solution, comprising a saturated aluminum hydroxide solution. The solid raw material inlet is used to add aluminum powders into the reaction chamber and the liquid raw material inlet is used to add water into the reaction chamber. The gas outlet is used to collect the produced hydrogen gas. The temperature controller is used to control the temperature of the reaction chamber within a preset reaction temperature range.
US08865116B2 Method for preparation of hematite iron oxide with different nanostructures and hematite iron oxide prepared thereby
Disclosed is a method for preparing hematite iron oxide having various nanostructures, including: preparing a mixture solution by adding iron chloride and caffeine to a solvent and magnetically stirring; and performing hydrothermal synthesis, wherein the solvent is selected from water, ethanol, propanol and methanol. In accordance with the present disclosure, hematite iron oxide (α-Fe2O3) superstructures of various shapes, including grape, cube, dumbbell and microsphere shapes, can be synthesized in different solvents using caffeine. The shapes can be controlled variously via a simple one-step synthesis route without using a growth-inducing agent and without separation based on size. The prepared hematite iron oxide exhibits high coercivity at room temperature owing to its fine crystal structures and anisotropic shapes. The hematite iron oxide nanoparticles having different nanostructures prepared according to the present disclosure may be widely useful in biological and biochemical applications as a material having peroxidase mimic activity and thus capable of replacing natural enzymes.
US08865112B2 Process and apparatus for multistage thermal treatment of rubber waste, in particular scrap tires
A process for multistage thermal treatment of rubber waste, in particular scrap tires, is proposed. The process comprises several steps of transferring a product granulate of rubber waste into three different sequencing heating zones of a reactor (10). In the heating zones (11a, 11b, 11c) the product granulate is heated at a first temperature between 100° to 200° C., preferably 150° to 180° C., then at a second temperature between 200° to 350° C. and at a third temperature between 300° to 600° C. The temperature is maintained until such time that no further oil is emitted within the respective heating zone. As a final step, the product granulate is removed from the reactor (10) and the desirable solid materials are separated.
US08865109B2 Systems and methods related to the formation of carbon-based nanostructures
Systems and methods for the formation of carbon-based nanostructures are generally described. In some embodiments, the nanostructures may be formed on a nanopositor. The nanopositor can comprise, in some embodiments, at least one of metal atoms in a non-zero oxidation state and metalloid atoms in a non-zero oxidation state. For example, the nanopositor may comprise a metal oxide, a metalloid oxide, a metal chalcogenide, a metalloid chalcogenide, and the like. The carbon-based nanostructures may be grown by exposing the nanopositor, in the presence or absence of a growth substrate, to a set of conditions selected to cause formation of carbon-based nanostructures on the nanopositor. In some embodiments, metal or metalloid atoms in a non-zero oxidation state are not reduced to a zero oxidation state during the formation of the carbon-based nanostructures. In some cases, metal or metalloid atoms in a non-zero oxidation state do not form a carbide during the formation of the carbon-based nanostructures.
US08865108B2 Process for making multi-walled carbon nanotubes and multi-walled carbon nanotubes formed therefrom
A process for making multi-walled carbon nanotubes includes contacting a hydrocarbon-containing gas with an electron beam-treated fly ash catalyst. The electron beam-treated fly ash catalyst contains a total amount of iron oxide and vanadium oxide of up to 5 wt. %. The multi-walled carbon nanotubes may be formed in a low pressure chemical vapor deposition apparatus.
US08865107B2 Highly concentrated nano-reinforcement suspensions for cementitious materials and method of reinforcing such materials
Highly concentrated carbon nanotube or other nano-reinforcement suspensions and/or masses are prepared for use as admixtures in cement base materials to make cementitious composite materials.
US08865106B2 Composite raw material, carbon fiber material and method for forming the same
In one embodiment of the disclosure, a composite raw material and a method for forming the same are provided. The method includes sulfonating a polycyclic aromatic compound to form a polycyclic aromatic carbon sulfonate (PCAS); and mixing the polycyclic aromatic carbon sulfonate and a polyacrylonitrile (PAN) to form a composite raw material. In another embodiment of the disclosure, a carbon fiber containing the composite raw material described above and a method for forming the same are provided.
US08865105B2 Graphene and its growth
The present invention provides graphene nuclei including monolayer single-crystalline graphene nuclei and a method of growing from them two-dimensional graphene dendrites, with aspect ratio of the main branches increasing with growth time, on catalytic metal surface using thermal chemical vapor deposition. By controlling the supply rates of the carbon etching gas and the carbon deposition species, it results in graphene branches being merged to form a two-dimensional monolayer single-crystalline graphene plate and further allows multiple graphene plates to merge and form a large-area continuous monolayer graphene plate.
US08865100B2 Monetizing remote gas using high energy materials
The present application is directed to a method and system for monetizing energy. More specifically, the invention is directed to the economically efficient utilization of remote or stranded natural gas resources. The invention includes importing a high energy density material into an energy market and distributing the high energy density material (HEDM) therein. The HEDM is produced from reduction of a material oxide such as boria into the HEDM, which may be boron. The reduction utilizes remote hydrocarbon resources such as stranded natural gas resources.
US08865099B1 Method and system for removal of mercury from a flue gas
Processes and methods exist for decreasing emissions of mercury upon combustion of fossil fuels such as coal. Halide salts can be effective when used at locations where they are thermally decomposed to form reactive halogen species, or in combination with an adsorbent material such as activated carbon. Halide salts, such as calcium bromide and sodium bromide, are not typically used at locations downstream of the economizer, where the temperature is typically below around 500° C., because these salts are non-thermolabile and do not decompose to produce reactive halogen species. However, in flue gas streams that certain flue gas constituents, such as sulfur trioxide or sulfuric acid, reactive halogen species can be produced via chemical reaction. These species react with elemental mercury through various means to form an oxidized form of mercury that is more easily captured in downstream pollution control devices such as particulate control devices or SO2 scrubbers.
US08865098B2 Method for removing contaminants from exhaust gases
In a method for removing a portion of contaminants, such as nitrogen oxides, from an exhaust gas stream of a combustion process, the exhaust gas stream is separated into two or more gas streams. At least one of the two or more gas streams is treated first by mixing with ozone. The treated gas stream is then fed to a scrubber where it is recombined with the untreated gas stream. Excess ozone present in the treated gas stream is consumed by oxidation of contaminants in the untreated gas stream before the combined gas stream is released to the atmosphere. The portion of the gas stream separated for mixing with ozone directly correlates to the amount of nitrogen oxides that are desired to be removed from the stream.
US08865094B2 Methods for separating medical isotopes using ionic liquids
A method for extracting a radioisotope from an aqueous solution, the method comprising: a) intimately mixing a non-chelating ionic liquid with the aqueous solution to transfer at least a portion of said radioisotope to said non-chelating ionic liquid; and b) separating the non-chelating ionic liquid from the aqueous solution. In preferred embodiments, the method achieves an extraction efficiency of at least 80%, or a separation factor of at least 1×104 when more than one radioisotope is included in the aqueous solution. In particular embodiments, the method is applied to the separation of medical isotopes pairs, such as Th from Ac (Th-229/Ac-225, Ac-227/Th-227), or Ra from Ac (Ac-225 and Ra-225, Ac-227 and Ra-223), or Ra from Th (Th-227 and Ra-223, Th-229 and Ra-225).
US08865093B2 Polymorph, polymorph screening system, and polymorph preparing and screening method
A polymorph, a polymorph screening system, and a polymorph preparing and screening method are disclosed. The polymorph preparing and screening method includes the following steps: providing a plurality of substrates of different materials; causing an organic material to grow crystals on the plurality of substrates through solution-cooling crystallization process, so that a plurality of polymorphs with different characteristics are prepared; and screening the plurality of polymorphs prepared in the previous step to obtain polymorphs with desired characteristics.
US08865092B2 Fixation and storage of biological organic samples
A method for automatically dosing a fixative solution in a flexible bag containing at least one biological organic sample comprises placing the bag with the sample in a dosing system (e.g., on a holder or weighing device), computing a required volume or weight of fixative solution as a function of the sample or the bag with the sample, and automatically transferring the computed volume or weight of fixative solution from a storage container into the bag. A system is also described for automatically dosing a fixative solution in a flexible bag containing at least one biological organic sample, a carrier for said flexible bags, and a storage cabinet for storing the carrier.
US08865091B2 Multilayer processing devices and methods
Sample processing devices that include transmissive layers and control layers to reduce or eliminate cross-talk between process chambers in the processing device are disclosed. The transmissive layers may transmit significant portions of signal light and/or interrogation light while the control layers block significant portions of signal light and/or interrogation light. Methods of manufacturing processing devices that include transmissive layers and control layers are also disclosed. The methods may involve continuous forming processes including co-extrusion of materials to form the transmissive layer and control layer in a processing device, followed by formation of the process chambers in the control layer. Alternatively, the methods may involve extrusion of materials for the control layer, followed by formation of process chambers in the control layer.
US08865085B2 System for maintaining freshness including flexible conducting polymer electrode
A system for maintaining the freshness of an object of preservation comprising an electrode made of a flexible conducting polymer. The system includes: an electrode module comprising a first electrode and a second electrode which face each other; and an electric field supply module generating an electric field between the first electrode and the second electrode by supplying a voltage to the electrode module, and where the first electrode is comprised of a flexible conducting polymer material.
US08865081B2 Method for producing aliphatic polyester having increased molecular weight
The problem to be solved by the present invention is to provide a method for continuously and effectively producing an aliphatic polyester having an increased molecular weight which prevents evaporation of diisocyanate at the step of mixing the diisocyanate with the aliphatic polyester prepolymer in a molten state at a temperature not lower than the melting point of the prepolymer and enables uniform mixing of the diisocyanate with the aliphatic polyester prepolymer. In order to solve this problem, the present invention provides a method for producing an aliphatic polyester having an increased molecular weight comprising the steps of: (i) quantitatively injecting a diisocyanate into an aliphatic polyester prepolymer which has a number average molecular weight of 5000 or higher and has terminal hydroxyl groups and in which at least one acid component is a succinic acid compound, in a molten state at a temperature not lower than the melting point thereof, wherein the amount of diisocyanate is equivalent to between one tenth and two times the amount of the hydroxyl groups in the aliphatic polyester prepolymer, (ii) quantitatively and continuously mixing the diisocyanate-containing aliphatic polyester prepolymer obtained at step (i) by a static mixer, discharging same from the static mixer, and then supplying same to a coupling reaction tank, and (iii) reacting the aliphatic polyester prepolymer with the diisocyanate in the coupling reaction tank.
US08865079B2 Hydrocarbon synthesis reaction apparatus, hydrocarbon synthesis reaction system, and hydrocarbon synthesis reaction method
A hydrocarbon synthesis reaction apparatus includes a reactor, and a synthesis gas supply line through which a synthesis gas is supplied to the reactor, and syntheses hydrocarbons by contacting the synthesis gas and the catalyst slurry in the reactor. The hydrocarbon synthesis reaction apparatus includes a spare supply line which is connected to the synthesis gas supply line, and supplies inert gas or hydrogen gas to the reactor through the synthesis gas supply line when supply of the synthesis gas to the synthesis gas supply line from the synthesis gas supply device is stopped, and a fluid heating device which heats at least one of a fluid which flows through a flowing line of the synthesis gas supply line located closer to the reactor than a portion connected with the spare supply line, and a fluid which flows through the spare supply line.
US08865075B2 Multi-task immunoaffinity device secured to a peripheral box and integrated to a capillary electrophoresis apparatus
The present invention relates to an immunoaffinity device for capturing one or more analytes present at high or low concentrations in simple or complex matrices. The device is designed as a modular, multi-task immunoaffinity device secured to a peripheral box and connected to capillary electrophoresis or liquid chromatography for the isolation, enrichment, separation and identification of polymeric macromolecules, primarily protein biomarkers. In one embodiment, two devices are coupled in-tandem to perform separately and sequentially microreactions and concentrations of proteins. In this embodiment, biological samples containing proteins can be subjected to proteolytic processing in the first device, and the resulting peptides subjected to selective purification and concentration in the second device.
US08865072B2 Analysis apparatus and analysis method
This analysis apparatus includes a transporter transporting the specimens to the first measurement unit and the second measurement unit, and a control portion so controlling the transporter as to transport a first specimen container, stored in the rack, storing a first specimen to the first measurement unit and as to transport a second specimen container, stored in the rack along with the first specimen container, storing a second specimen to the second measurement unit.
US08865070B2 Machine for the production of pharmaceutical products
A machine for the preparation of pharmaceutical products has a pocket conveyor, mobile along a loop-shaped path and provided with a plurality of pockets, each adapted to receive and withhold a respective container, and a transfer device for transferring the containers with a rectilinear motion between the respective pockets and at least one operating station for executing an operation on the containers themselves.
US08865066B2 Sterilization method
A method of sterilizing a material, said method comprising the steps of: a) providing a sterilizing composition comprising (i) peracetic acid and (ii) a stabilizer selected from the group consisting of citric acid, isocitric acid, aconitic acid and propane-1,2,3-tricarboxylic acid; b) introducing such sterilizing composition into a hot gaseous stream to produce a peracetic acid vapor; and c) contacting such peracetic acid vapor with the material to be sterilized. The use of such an organic acid stabilizer results in an unexpected reduction in the amount of residue deposited on the heating surface employed to vaporize the sterilizing composition.
US08865060B2 Austenitic stainless steel
An austenitic stainless steel, which consists of by mass percent, C: not more than 0.02%, Si: not more than 1.5%, Mn: not more than 2%, Cr: 17 to 25%, Ni: 9 to 13%, Cu: more than 0.26% not more than 4%, N: 0.06 to 0.35%, sol. Al: 0.008 to 0.03%. One or more elements selected from Nb, Ti, V, TA, Hf, and Zr in controlled amounts can be included with the balance being Fe and impurities. P, S, Sn, As, Zn, Pb and Sb among the impurities are controlled as P: 0.006 to 0.04%, S: 0.0004 to 0.03%, Sn: 0.001 to 0.1%, As: not more than 0.01%, Zn: not more than 0.01%, Pb: not more than 0.01% and Sb: not more than 0.01%. The amounts of S, P, Sn, As, Zn, Pb and Sb and the amounts of Nb, Ta, Zr, Hf, and Ti are further controlled using formulas.
US08865058B2 Heat treatment furnace
A furnace heats through both infrared radiation and convective air utilizing an infrared/purge gas design that enables improved temperature control to enable more uniform treatment of workpieces. The furnace utilizes lamps, the electrical end connections of which are located in an enclosure outside the furnace chamber, with the lamps extending into the furnace chamber through openings in the wall of the chamber. The enclosure is purged with gas, which gas flows from the enclosure into the furnace chamber via the openings in the wall of the chamber so that the gas flows above and around the lamps and is heated to form a convective mechanism in heating parts.
US08865056B2 Bevel head for controlling a cutting torch to cut plate with weld preparation
A bevel head apparatus includes tilt, rotation, and vertical positioning with a cutting torch of a numerically controlled plate cutting machine. The apparatus has a back panel that attaches to the cutting machine and provides vertical movement of the cutting torch, a drive box coupled with the back panel houses electronics and mechanical components, an arm coupled to the drive box provides rotational movement of the cutting torch, and a pantograph coupled with the arm provides tilt movement to the cutting torch attached to the pantograph. Tilt, rotation, and vertical positioning of the cutting torch is controlled by the electronics and mechanical components. The bevel head apparatus also include a laser for measuring distance to determine and control a height of the cutting torch above the flat plate.
US08865053B2 Process for the production of moldings
The present invention relates to a polymer powder which comprises nylon-11, and to the use of this powder for shaping processes, and also to moldings produced from this polymer powder.The shaping processes are layer-by-layer processes which use powders, where regions of the respective layer are selectively melted via introduction of electromagnetic energy. The selectivity may—with no intention of restricting the invention thereto—be achieved via masks, application of inhibitors, of absorbers, or of susceptors, or via focusing of the energy introduced. After cooling, the regions then solidified can be removed in the form of moldings from the powder bed.Compared with moldings composed of conventional powders, the moldings constructed using the inventive powder by one of the inventive processes exhibit marked advantages in terms of component properties, particularly surface finish. There are also improvements here in processing and in recycling capability when comparison is made with conventional polyamide powders.
US08865048B2 Injection molding nozzle with dynamic seal
A manifold, in a first pocket, defines a manifold orifice to supply material to a nozzle in a second pocket. A support ring in the second pocket maintains the nozzle stationary within the second pocket. A bushing extends between the pockets, fixedly attached to the manifold and laterally movable with respect to the pockets and the nozzle. At ambient temperature, the centers of the nozzle and manifold orifices are laterally offset from one another, a preload is defined between the nozzle and the bushing, another preload is defined between the manifold and the nozzle, and a gap is defined between the support ring and the pocket. In operation, when the various components thermally expand, the manifold moves laterally within the first pocket, and the nozzle remains substantially stationary within the second pocket, such that the centers of the nozzle and manifold orifices are laterally aligned, and the gap is closed.
US08865047B2 Solid freeform fabrication of easily removeable support constructions
A support construction and a method of creating a support construction in a volume generated by solid freeform fabrication, where the support construction includes layers of supporting materials, such layers comprising a continuous strip of material within such volume such that when the strip is lifted or pulled, the layers of supporting materials including the strip are removed together from the volume.
US08865045B2 Multi-layered golf balls having a thin outer cover
Multi-layered golf balls having an inner core, at least one intermediate layer, and outer cover are provided. The outer cover is made from am ultra-low melt index (ULMI) thermoplastic material using an in-molding coating process that involves applying a thin layer of the material to the interior surface of the cover mold members. Preferably, the ultra-low melt index material is a highly neutralized ionomer ethylene-based copolymer. The cover layers made from these highly neutralized polymers (HNPs) are thin and uniform and provide the golf ball with good playing performance properties. Yet, the cover layers also are tough and provide the golf ball with good impact durability.
US08865041B2 Extruder and process for extruding a polymer
Process for extrusion of polymer by feeding a polymer feedstock to the feed port of an extruder having (i) two or more barrel sections arranged sequentially from (a) an upstream feed barrel section to which polymer feedstock to be extruded is fed, the upstream feed barrel section containing two screws each having a diameter of X, to (b) a downstream barrel section from which melted polymer is passed to a die and extruded, and (ii) a feed port for feeding polymer feedstock to be extruded into the extruder at its upstream end. The polymer feedstock is in the form of a powder, and the feed port area is a rectangular shape with width limited by the width of the upstream feed barrel section to 2*X and with a length greater than 2.5*X. The total area of the feed ports through which polymer feedstock is introduced is greater than 5*X2.
US08865039B2 Method of making a concrete block
Molds and processes that permit high-speed, mass production of retaining wall blocks having patterned or other processed front faces, as well as retaining wall blocks formed by such processes. The invention permits the front face of the block to be impressed with a pattern or otherwise directly processed, to allow the formation of pre-determined block front faces, while at the same time facilitating high-speed, high-volume production of blocks. A mirror image of the desired pattern can be created on a stripper shoe by selecting a desired three-dimensional surface from a naturally occurring or man made object and digitally scanning the selected three-dimensional pattern to create scanned data. The scanned data can then be used to machine a face of the stripper shoe that is the mirror image of the selected pattern.
US08865035B2 Method for controlling RF energy applied to molds
Each platform mounted mold assembly for plastic tubing includes a circuit board containing parameters defining elements of the forming, molding, tipping or welding operation to be undertaken on the tubing. A control unit includes an RF generator for providing the RF energy to effect the forming, molding, tipping or welding process, a source of air under pressure to operate the mechanical elements attendant each mold assembly, various sensors and a multiplex unit. In operation, the control unit serially addresses each of the mold assemblies, senses the parameters attendant the mold and applies the appropriate power level of RF energy for a specific duration and temperature while activating the mechanical aspects of the mold assembly. The mold assemblies may be serially activated through a multiplex unit or in a particular sequence that may be operator controlled.
US08865031B2 Method and apparatus for applying a Mid-IR graded-index microstructure to an optical fiber tip to achieve anti-reflective properties
A method and apparatus for applying a mid-IR graded microstructure to the end of an As2S3 optical fiber are presented herein. The method and apparatus transfer a microstructure from a negative imprint on a nickel shim to an As2S3 fiber tip with minimal shape distortion and minimal damage-threshold impact resulting in large gains in anti-reflective properties.
US08865030B2 Microcapsules having a radiation-induced or thermal release
The present invention relates to microcapsules comprising a capsule core comprising a lipophilic substance and also at least one compound which absorbs electromagnetic radiation from the wavelength range from 700 nm to 1 m, and a capsule wall synthesized from 40 to 80% by weight of one or more monomers (monomers I) selected from C1-C24 alkyl esters of acrylic and/or methacrylic acid, acrylic acid, methacrylic acid, and maleic acid, 20 to 60% by weight of one or more di- or polyfunctional monomers (monomers II) which are sparingly soluble or insoluble in water, and 0 to 40% by weight of one or more other monomers (monomers III), based in each case on the total weight of the monomers, and also to microcapsules comprising at least one epoxy tackifier resin and if desired a compound which absorbs electromagnetic radiation from the wavelength range from 700 nm to 1 m, to a process for preparing them, to their use in pressure sensitive adhesives, and also to a method of adhesively bonding at least two substrates.
US08865028B2 ZnO-based varistor composition
Disclosed herein is a ZnO-based varistor composition including zinc oxide (ZnO) as a main component and a calcium (Ca)-containing compound as an accessory component. The varistor composition provides excellent electrostatic discharge (ESD) characteristics because it has excellent physical properties, such as a nonlinear coefficient, a clamping voltage ratio, a surge absorbance and the like, and, particularly, does not include Bi2O3. Further, the varistor composition provides high work safety because it does not include Sb2O3 that is regulated for environmental purposes. Further, the varistor composition can reduce the manufacturing cost of a varistor because it does not Pr-based components that require high-temperature sintering and increase the manufacturing cost of a varistor. Particularly, the varistor composition has a low clamping voltage as well as a low capacitance.
US08865023B2 (HALO)silicate-based phosphor and manufacturing method of the same
Disclosed are a (halo)silicate-based phosphor and a manufacturing method of the same. More particularly, the disclosed phosphor is a novel (halo)silicate-based phosphor manufactured by using a (halo)silicate-based host material containing an alkaline earth metal, and europium as an activator.
US08865019B2 Method of inhibiting free radical polymerization of styrene
The method of inhibiting free radical polymerization of styrene includes adding multi-walled carbon nanotubes are added to the styrene monomer. The addition of the multi-walled carbon nanotubes at a concentration of 5% by weight is found to provide effective inhibition of the polymerization of the styrene. Greater decreases in the conversion rate of styrene to polystyrene are found through the addition of multi-walled carbon nanotubes functionalized with a carboxylic group (COOH). Still greater decreases in the conversion rate of styrene to polystyrene are found through the addition of multi-walled carbon nanotubes functionalized with octadecylamine (C18H39N). The multi-walled carbon nanotubes may also be functionalized with other functional groups, such as octadecanoate, polyethylene glycol or phenol. The functionalized multi-walled carbon nanotubes only require addition at a concentration of 1% by weight to be effective in polymerization inhibition.
US08865016B2 Biodegradable, frost proof heat-transfer fluid, use thereof in near-surface geothermal installations, and a concentrate for preparing same
Biodegradable, frost proof heat-transfer fluid, use thereof in near-surface geothermal installations, and a concentrate: subject matter of the present invention is the use of a triazole-free composition which as well as water comprises a) 9.2% to 49.5% by weight of at least one C2 to C3 alkylene glycol, C2 to C3 polyalkylene glycol or glycerol, b) 0.1% to 4% by weight of at least one corrosion inhibitor, with the provisos that c) the composition is readily degradable biologically in accordance with test method OECD 301 A, d) the composition has an anaerobic biodegradability of at least 75% in accordance with test method OECD 311, e) the corrosion inhibitor or all corrosion inhibitors used are readily degradable biologically in accordance with OECD 301 A (for water-soluble corrosion inhibitors) or OECD 301 B (for corrosion inhibitors of low water-solubility), in near-surface geothermal installations as a heat-transfer fluid.
US08865010B2 Pattern forming method and imprint mold manufacturing method
In one embodiment, a pattern forming method includes: forming a functional layer having a functional group to cross-link a first polymer on a substrate; forming a diblock copolymer layer having the first polymer and a second polymer on the functional layer; self-assembling the diblock copolymer layer to form a self-assembled layer, the self-assembled layer having a first domain corresponding to the first polymer, and a plurality of second domains corresponding to the second polymer and surrounded by or interposed in the first domain; cross-linking the first polymer in the self-assembled layer with the functional group in the functional layer to form a bonding layer disposed in the self-assembled layer and bonded to the functional layer; and washing or etching the self-assembled layer to remain the bonding layer.
US08865007B2 Method for making three-dimensional nano-structure array
A method for making three-dimensional nano-structure array is provided. The method includes following steps. A base is provided. A mask layer is located on the base. The mask layer is patterned, and a number of bar-shaped protruding structures is formed on a surface of the mask layer, a lot is defined between each of two adjacent protruding structures of the number of protruding structures to expose a portion of the base. The exposed portion of the base is etched through the slot so that the each of two adjacent protruding structures begin to slant face to face until they are contacting each other to form a protruding pair. The mask layer is removed.
US08865006B2 Concrete washout separation system
The invention pertains generally to waste management and debris removal, and more particularly to systems and methods for separating and recovering the water and solids from a volume of concrete washout following the washing out of concrete mixer trucks and other concrete mixing and delivery equipment.
US08865004B2 Device for purifying water
The invention relates to a device for purifying water contaminated with organic substances, which is drained or collected from filters, especially fuel filters or elements of a fuel system. Hydroxyl radicals are formed from the water by means of a separating device where the hydroxyl radicals oxidize the impurities, especially organic substances, as much as possible, and convert them into compounds such as CO2.
US08865000B2 Utilization of the naturally occurring magnetic constituents of ores
The present invention relates to a process for separating at least one first material from a mixture comprising this at least one first material, at least one second material and magnetic particles, which comprises the following steps (A) at least partial removal of the magnetic particles by application of a magnetic field gradient, optionally in the presence of at least one dispersing medium, to give a mixture comprising at least one first material and at least one second material and a reduced amount of magnetic particles, (B) contacting of the mixture comprising at least one first material and at least one second material from step (A) with magnetic particles so that the at least one first material and the magnetic particles agglomerate, (C) separation of the agglomeration product from the mixture from step (B) by application of a magnetic field gradient and (D) dissociation of the agglomeration product separated off in step (C) in order to obtain the at least one first material and the magnetic particles separately, and also a control and/or regulation device for a corresponding apparatus.
US08864993B2 Process for removing ammonium from a wastewater stream
A process that utilizes ammonium oxidizing bacteria (AOB) and anaerobic ammonium oxidizing (ANAMMOX) bacteria to remove ammonium from a wastewater stream. Sludge separated from the wastewater in a mainstream is processed in a sidestream that includes an anaerobic digester, a dewatering system, and a biofilm reactor. The anaerobic digester produces digested sludge that is dewatered, producing reject water that includes a relatively high ammonium concentration and a relatively low organic carbon concentration and a relatively high temperature. The reject water is treated in a sidestream deammonification biofilm reactor that includes biofilm carriers seeded with AOB and ANAMMOX bacteria that are effective to remove ammonium from the reject water. AOB and ANAMMOX bacteria on the media carriers is utilized to contact the wastewater in the mainstream and to remove ammonium therefrom.
US08864990B2 Header for module of hollow fiber membranes and method of potting hollow fibers
Hollow fiber membranes are potted by injecting a liquid material into a substantially closed cavity (44) containing the fibers. The cavity may be formed in part by the interaction of a mold a permeate pan (52) and a layer of an adhesive pre-applied to a bundle of the membranes.
US08864987B2 Mechanically agitated, inner circulation reactor for resin ion exchange and adsorption
Disclosed is an internal circulation resin ion exchange adsorption reactor with a mechanical stirrer. The upper part ⅔˜⅘ of the reactor main body is an open cylinder and the lower part ⅕˜⅓ is a cone-shaped body with a slope of 30°±10°. A bell-jar shaped reaction slot with a turbine water stirrer inside is located in the center of the reactor main body. The reactor main body is equipped with a cylindrical guide plate. A water collection weir, an inclined tube separator and an annular resin collection hopper are located between the shell of the reactor main body and the guide plate. The reactor is equipped with a water inlet pipe and a water outlet pipe. A resin removal pipe is connected with the annular resin collection hopper and a resin desorption slot respectively, and a regenerated resin reflux pipe is connected to the bell-jar shaped reaction slot.
US08864982B2 Methods for obtaining bitumen from bituminous materials
A method of extracting bitumen from bituminous material. In some embodiments, the method may include loading a bitumen material in a column, followed by feeding a first quantity of first solvent into the column. The method may also include collecting the bitumen-enriched solvent exiting the column. A quantity of the bitumen-enriched solvent may then be fed into the column. In some embodiments, the method may include simultaneously loading bitumen material and a first solvent in a column, followed by feeding additional first solvent into the column. The method may also include collecting bitumen-enriched solvent exiting the column, and feeding a quantity of the bitumen-enriched solvent into the column.
US08864981B2 Feed mixtures for extraction process to produce rubber processing oil
Deasphalted residual oil (DAO) and the aromatics-rich extract that is derived from DAO have low polycyclic aromatics contents, relatively low aniline points, and high flash points. They form blending stocks that improve properties of mixed feedstocks to consistently produce environmentally qualified rubber processing oil (RPO) by extraction under low solvent-to-oil ratios and moderate extraction temperatures. Distilling a petroleum crude oil under atmospheric pressure generates a bottom residual oil which is then subject to vacuum distillation to yield a bottom residual oil. DAO is produced by removing the asphalt from the vacuum bottom residual oil through extraction with light paraffinic solvent. The extract of DAO is a co-product in the production of the bright stock of the lubricating oil through extraction. The feedstock is mixed with the extract from a petroleum fraction boiling in lube oil range. Liquid-liquid counter-current extraction yields a raffinate stream; removal of solvent therefrom produces the RPO.
US08864980B2 Hydrotreating process
A process for hydrotreating a first aromatics- and sulfur-containing hydrocarbon feed using a fresh supported CoMo catalyst, includes treating the fresh catalyst under first hydrotreating conditions with a second hydrocarbon feed having a lower aromatics content than the first feed.
US08864979B2 Process and apparatus for fluid catalytic cracking
One exemplary embodiment can be a process for fluid catalytic cracking. The process can include sending a first catalyst from a first riser reactor and a second catalyst from a second riser reactor to a regeneration vessel having a first stage and a second stage. The first catalyst may be sent to the first stage and the second catalyst may be sent to the second stage of the regeneration vessel. Generally, the first stage is positioned above the second stage.
US08864978B2 Supercritical water process to upgrade petroleum
Provided is a process for the supercritical upgrading of petroleum feedstock, wherein the process includes the use of a start-up agent, wherein the use of the start-up agent facilitates mixing of the petroleum feedstock and water, thereby reducing or eliminating the production of coke, coke precursor, and sludge.
US08864970B2 Methods and devices of separating molecular analytes
A method of separating a mixture of a plurality of molecular analytes having different isoelectric points (pIs). The method comprises placing a solution containing a mixture of a plurality of molecular analytes in a separation volume, generating a pH profile having a plurality of pH zones across an axis of the separation volume, and adjusting a profile of the pH profile to induce a migration of a first molecular analyte along the axis apart from a second molecular analyte. The first and second molecular analytes having different pIs.
US08864969B2 Electro-diffusion enhanced bio-molecule charge detection using electrostatic interaction
According to one aspect, the disclosure is directed to an example embodiment in which a circuit-based arrangement includes a circuit-based substrate securing a channel, with an effective width that is not limited by the Debye screening length, along a surface of the substrate. A pair of reservoirs are included in or on the substrate and configured for containing and presenting a sample having bio-molecules for delivery in the channel. A pair of electrodes electrically couple a charge in the sample to enhance ionic current flow therein (e.g., to overcome the electrolyte screening), and a sense electrode is located along the channel for sensing a characteristic of the biological sample by using the electrostatic interaction between the enhanced ionic current flow of the sample and the sense electrode. Actual detection occurs by using a charge-signal processing circuit to process the sensed charge signal and, therefrom, provide an output indicative of a signature for the bio-molecules delivered in the channel.
US08864966B2 Coating mask for electrolytically coating a peripheral region on an outer surface of a cylindrical body
The invention relates to a coating mask (1) for electrolytically coating the piston ring groove (39) of a piston (38), which is made of an elastically deformable material and has openings (3 to 10) that are arranged axially and are distributed in a uniform manner over the periphery, into which rods (11 to 18) of an expansion device (19) can be introduced, the rods being arranged in a displaceable manner such that the expansion device (19) can increase the radial diameter of the coating mask (1) and also the inner opening (2) so that the piston (38) can be introduced into the inner opening (2). The radial diameter of the coating mask (1) is selected in such a manner that after the reduction of radial diameter of the coating mask (1) and the inner opening, the elastically tensed coating mask (1) presses sealing lips (44, 45) of the coating groove (37) against the piston (38), on both sides of the piston ring groove (39).
US08864963B2 Carbon dioxide capture using resin-wafer electrodeionization
The present invention provides a resin-wafer electrodeionization (RW-EDI) apparatus including cathode and anode electrodes separated by a plurality of porous solid ion exchange resin wafers, which when in use are filled with an aqueous fluid. The apparatus includes one or more wafers comprising a basic ion exchange medium, and preferably includes one or more wafers comprising an acidic ion exchange medium. The wafers are separated from one another by ion exchange membranes. The fluid within the acidic and/or basic ion exchange wafers preferably includes, or is in contact with, a carbonic anhydrase (CA) enzyme to facilitate conversion of bicarbonate ion to carbon dioxide within the acidic medium. A pH suitable for exchange of CO2 is electrochemically maintained within the basic and acidic ion exchange wafers by applying an electric potential across the cathode and anode.
US08864959B2 Method for manufacturing workpieces with ion-etched surface
Planetary carriers (22) for workpieces mounted on a carousel (19) are provided within a vacuum chamber. A source (24) for a cloud comprising ions (CL) is provided so that a central axis (ACL) of the cloud intercepts the rotary axis (A20) of the carousel (19). The cloud (CL) has an ion density profile at the moving path (T) of planetary axes (A22) which drops to 50% of the maximum ion density at a distance from the addressed center axis (ACL) which is at most half the diameter of the planetary carriers (22). When workpieces upon the planetary carriers (22) are etched by the cloud comprising ions material which is etched off is substantially not redeposited on neighboring planetary carriers but rather ejected towards the wall of the vacuum chamber.
US08864958B2 Method and sputter-deposition system for depositing a layer composed of a mixture of materials and having a predetermined refractive index
A method and sputter-deposition system for depositing a layer composed of a mixture of materials and having a predetermined refractive index are provided. The sputter-deposition system includes a plurality of target cathodes, each of which comprises a target material having a different composition, that are powered by a single DC power supply. The plurality of target cathodes are cosputtered to deposit a layer composed of a mixture of materials on a substrate. The composite refractive index of the layer is controlled by adjusting an operating parameter of the plurality of target cathodes. Suitable operating parameters include cathode power, cathode voltage, cathode current, an angle between a cathode support and the substrate, and a flow rate of a reactive gas.
US08864955B2 Process to apply heater function to plastic substrate
The invention is related to a process to apply a heater function to a plastic glass that was made of a polycarbonate. The process includes a sputtering process that allows producing high performance heater function on a plastic glass. Another aspect of the invention is the plastic glass mirrors produced by the inventive process.
US08864953B2 Cyclonic reactor with non-equilibrium gliding discharge and plasma process for reforming of solid hydrocarbons
A reactor for reforming a hydrocarbon, and associated processes and systems, are described herein. In one example, a reactor is provided that is configured to use non-equilibrium gliding arc discharge plasma. In another example, the reactor uses a vortex flow pattern. Two stages of reforming are described. In a first stage, the hydrocarbon absorbs heat from the wall of the reactor and combusts to form carbon dioxide, carbon monoxide, and water. In a second stage, a gliding arc discharge is use to form syngas, which is a mixture of hydrogen gas and carbon monoxide. The heat generated by the combustion of the first stage transfers to the wall of the reactor and heated products of the second stage mix with incoming hydrocarbon to provide for partial recuperation of the reaction energy.
US08864950B2 Processes for producing acrylic acids and acrylates
A process for producing an acrylate product. The process comprises the step of providing a crude product stream comprising the acrylate product and an alkylenating agent. The process further comprises the step of separating at least a portion of the crude product stream to form an alkylenating agent stream and an intermediate product stream. The alkylenating agent stream comprises at least 1 wt % alkylenating agent and the intermediate product stream comprises acrylate product. The separating is performed in at least one column at an operating pressure ranging from 40 kPa to 80 kPa.
US08864938B2 Vacuum peeling apparatus and method
The invention relates generally to a vacuum peeling apparatus and a vacuum peeling method. The vacuum peeling apparatus may include a chamber, a sealing maintain frame disposed inside the chamber, a first air tube disposed along a bottom end of the sealing maintain frame and configured to be expandable, a peeling prevention panel configured so as to be inserted into a center of the sealing maintain frame, and a second air tube disposed along an end of the peeling prevention panel.
US08864927B2 Method for making carbon nanotube film
A method for making a carbon nanotube film is provided. First, a carbon nanotube array is formed on a grown substrate. The carbon nanotube array is pressed with a first substrate using a first pressing force to form a carbon nanotube film precursor. Then the first substrate and the grown substrate are separated, and the carbon nanotube film precursor is transferred onto the first substrate. After that, the carbon nanotube film precursor is pressed using a second substrate with a second pressing force. Lastly, the first substrate and the second substrate is separated, with part of the carbon nanotube precursor transferred to the second substrate to form the carbon nanotube film.
US08864925B2 Method for producing laminated electronic component, and laminated electronic component
A method of manufacturing a laminated electronic part includes fabricating first and second laminated sheets by laminating an insulating function layer made of an unsintered ceramic material and a conductor layer, having a plurality of conductors two-dimensionally arranged in a vertical direction and in a horizontal direction to make up part of circuit components; cutting the first and second laminated sheets into sticks to create a plurality of first and second laminate sticks; fabricating a third laminated sheet by rotating the second laminate sticks by 90°, arranging the second laminate sticks to be each sandwiched between the first laminate sticks, and thermocompression bonding them for integration; singulating the third laminated sheet into chips and creating sintered bodies by sintering the unsintered chips to integrate the first laminate with the second laminate.
US08864923B1 Ballistic modifier formulation for double base propellant
A double base propellant modifier uses a combination of a lead component, a tin component and a copper component in physical contact to effect super-rate burning of double base propellants with defined plateau and mesa burning rate characteristics.
US08864922B2 Method for manufacturing a precipitation-hardening cold-rolled steel sheet having excellent yield ratios
A method for manufacturing a precipitation hardening cold-rolled steel sheet with an excellent yield ratio. The method may include the steps of hot rolling a steel slab with finish rolling at a temperature of Ar3 transformation point or more to form a hot-rolled steel sheet, coiling the hot-rolled steel sheet at a temperature of 550-600 ° C., cold rolling the hot-rolled steel sheet at a reduction ratio of 50% or more; and recovery-recrystallization annealing the cold-rolled steel sheet at a line speed of 150-200 mpm and at a temperature of 780-820° C. in a continuous annealing furnace. The recovery-recrystallization annealing may provide a recrystallization ratio of 65-75%. The steel slab includes, by weight %: C: 0.07-0.10%, Mn: 1.41-1.70%, P: 0.05-0.07%, S: 0.005% or less, N: 0.005% or less, acid-soluble Al: 0.10-0.15%, Nb: 0.06-0.09%, B: 0.0008-0.0012%, Sb: 0.02-0.06%, and the balance comprising Fe and other unavoidable impurities.
US08864919B2 Nickel based forged alloy, gas turbine member using said alloy and gas turbine using said member
It is an objective of the invention to provide a Ni-based forged alloy having good large ingot formability and good hot formability as well as high mechanical strength at high temperature. There is provided a Ni-based forged alloy comprising: 0.001 to 0.1 mass % of C; 0.001 to 0.01 mass % of B; 16 to 22 mass % of Cr; 0.5 to 1.5 mass % of Al; 0.1 to 6.0 mass % of W; 3.5 to 5.5 mass % of Nb; 0.8 to 3.0 mass % of Ti; 16 to 20 mass % of Fe; 2.0 mass % or less of Mo; and the balance including Ni and unavoidable impurities, in which: a segregation parameter Ps defined by a formula of “Ps (mass %) =1.05×[Al concentration (mass %)]+0.6×[Ti concentration (mass %)]−0.8×[Nb concentration (mass %)]−0.3×[Mo concentration (mass %)]” satisfies a relationship of “Ps≧−3.0 mass %”; and a total amount of W and Mo is 1.75 atomic % or less.
US08864913B2 Filter cleaning system and method
A filter cleaning system for cleaning a filter element is provided. The filter cleaning system includes a set of pulse nozzles and a compressed air supply, which rotate together during a cleaning cycle to release pulse blasts at predetermined time intervals to clean the filter element.
US08864907B2 Silicon substrate and manufacturing method of the same
A condition of a single crystal manufacturing step subjected to the Czochralski method applying an initial oxygen concentration, a dopant concentration or resistivity, and a heat treatment condition is determined simply and clearly on the basis of the conditions of a wafer manufacturing step and a device step so as to obtain a silicon wafer having a desired gettering capability. A manufacturing method of a silicon substrate which is manufactured from a silicon single crystal grown by the CZ method and provided for manufacturing a solid-state imaging device is provided. The internal state of the silicon substrate, which depends on the initial oxygen concentration, the carbon concentration, the resistivity, and the pulling condition of the silicon substrate, is determined by comparing a white spot condition representing upper and lower limits of the density of white spots as device characteristics with the measured density of white spots.
US08864901B2 Calcium sulfoaluminate cement-containing inorganic polymer compositions and methods of making same
Inorganic polymer compositions and methods for their preparation are described herein. The compositions include the reaction product of a reactive powder, an activator, and optionally a retardant. The reactive powder includes fly ash, calcium sulfoaluminate cement, and less than 10% by weight portland cement. In some examples, the composition is substantially free from alkanolamines. In some examples, the ratio of water to reactive powder is from 0.06:1 to less than 0.2:1. Also described herein are building materials including the compositions.
US08864894B2 Resist underlayer film forming composition containing silicone having onium group
There is provided a resist underlayer film forming composition for lithography for forming a resist underlayer film capable of being used as a hard mask or a bottom anti-reflective coating, or a resist underlayer film causing no intermixing with a resist and having a dry etching rate higher than that of the resist. A film forming composition comprising a silane compound having an onium group, wherein the silane compound having an onium group is a hydrolyzable organosilane having, in a molecule thereof, an onium group, a hydrolysis product thereof, or a hydrolysis-condensation product thereof. The composition uses as a resist underlayer film forming composition for lithography. A composition comprising a silane compound having an onium group, and a silane compound having no onium group, wherein the silane compound having an onium group exists in the whole silane compound at a ratio of less than 1% by mol, for example 0.01 to 0.95% by mol. The hydrolyzable organosilane may be a compound of Formula: R1aR2bSi(R3)4−(a+b). A resist underlayer film obtained by applying the composition as claimed in any one of claims 1 to 14 onto a semiconductor substrate and by baking the composition.
US08864889B2 Dust suppression apparatus
A dust suppression apparatus comprising: (a) a turntable; (b) an engine; (c) a water mist blower comprising an air conduit, a plurality of water nozzles positioned so as to supply a spray of water to the air conduit, and a fan positioned so as to supply a stream of air through the air conduit, the water mist blower and the engine mounted on the turntable, the turntable adapted to permit the air conduit to be rotated horizontally, and the air conduit mounted so as to permit the air conduit to tilt vertically; (d) a water conduit adapted to supply pressurized water to the plurality of water nozzles; (e) a belt drive connected to the engine and adapted to supply power to the fan, and (f) a constant velocity joint connecting the belt drive to the fan.
US08864884B2 Contaminant control filter with fill port
Filters, methods, and an apparatus for filling housings and both encapsulated porous and non-porous spaces with contaminant control media for placement in electronic enclosures, such as disk drive enclosures, are disclosed. In one embodiment, a filter assembly includes a housing comprising an internal cavity configured to receive contaminant control media, a fill port in communication with the internal cavity, and an opening in communication with the internal cavity, and filter media at least partially covering the opening; and contaminant control media occupying the internal cavity. Contaminant control media is deposited within the internal cavity via the fill port by means of creating a negative pressure within the internal cavity. The application of a partial vacuum facilitates movement of the contaminant control media into the internal cavity and minimizes the contamination of the filter, housing, and work space common to other loose fill filling methods.
US08864882B2 Inline water trap
An inline water trap including a filter component and a panel connector configured to interface with a patient gas monitor. In one embodiment the inline water trap indicates to the patient gas monitor that it is in place and that the patient gas monitor may begin intaking and analyzing the filtered patient sample. The inline water trap receives a patient sample and filters water and contaminants from the sample before allowing the remaining gas portion of the sample to pass through to the patient gas monitor, thereby protecting the patient gas monitor from damage. One embodiment of the inline water trap additionally contains an RFID tag to indicate to the patient gas monitor that the correct type of inline water trap is engaged.
US08864880B2 Mechanical gas pocket preventer/breaker
Described is an apparatus useful for mechanically delaying formation of or breaking a pocket and a method of delaying formation of or breaking a gas pocket employing the apparatus.
US08864876B2 Indirect and direct method of sequestering contaminates
The invention generally relates to a method for sequestration contaminates. More particularly, the invention relates to a significant performance enhancement over existing mineral carbonation processes through the use of a high mass transfer system and an efficient pH swing reaction. More particularly, aspects of the invention are directed to direct and indirect methods of sequestering contaminates.
US08864874B2 Method for preparing sponge titanium from sodium fluotitanate by aluminothermic reduction
The invention provides a method for preparing sponge titanium from sodium fluotitanate by aluminothermic reduction, comprising the following steps: a reaction step: aluminum and zinc are mixed under a vacuum state, and sodium fluotitanate is then added into the mixture for reaction; a separation step: the product resulting from the complete reaction stands still and is then introduced with inert gas, and NaF and AlF3 in upper-layer liquid phase are extracted; and a distillation step: Zn in the remaining product Zn—Ti is distilled out under a vacuum state, wherein the mass ratio of the aluminum to the zinc is 1:2 to 1:10.
US08864872B2 Method for the recovery of uranium from pregnant liquor solutions
A method for the recovery of uranium from pregnant liquor solutions that comprise levels of chloride of 5 to 80 g/L by using an amino phosphonic functionalized resin. The method includes providing an amino phosphonic functionalized resin; providing a pregnant liquor solution comprising and uranium; passining the pregnant liquor solution over the amino phosphonic functionalized resin to separate the uranium from the pregnant liquor solution; and eluting the uranium.
US08864869B2 Hearth roll in a continuous annealing furnace and its production method
The hearth roll for a continuous annealing furnace is able to suppress the occurrence of buildup on the hearth roll surface and able to be stably used for a long period under the high temperature environment. The hearth roll has a cermet coating comprised 50 to 90 vol % of ceramic and the balance of a heat resistant alloy on its surface, the ceramic containing Cr3C2: over 50 to 90 vol %, Al2O3: 1 to 40 vol %, Y2O3: 0 to 3 vol %, and ZrB2: 0 to 40 vol % and having a balance of unavoidable impurities and pores, the heat resistant alloy containing Cr: 5 to 20 mass %, Al: 5 to 20 mass %, and one or both of Y and Si: 0.1 to 6 mass % and has a balance of one or both of Co and Ni and unavoidable impurities.
US08864866B2 Filter assemblies; components and features thereof; and, methods of use and assembly
Air cleaner assemblies, components therefor, and features thereof are described. Also described are methods of assembly and use. In depicted examples, the air cleaner assemblies and components optionally use advantageous housing seal features. Also, an advantageous resonator/sonic choke arrangement, which is optional and which can be used without the advantageous housing seal, is described. Methods of assembly and use are described.
US08864865B2 Air filter element, filter housing and filter arrangement
An air filter element (10) with a cylindrical central pipe (11) is provided wherein at one end of the central tube (11) a device (18) for transmission of torque from a tool to the air filter element (10) is provided and at the other end of the central tube (11) a fastening device (14) for detachably mounting the filter element (10) in a cylindrical support body (21) by means of an insertion/rotation movement is provided.
US08864860B2 Polishing composition
To provide a polishing composition which can satisfy both suppression of the surface topography and a high stock removal rate, in a polishing step in the production of a wiring structure.A polishing composition comprising abrasive grains, a processing accelerator, a nonionic surfactant represented by R-POE (I) (wherein R is a C10-16 alkyl group having a branched structure, and POE is a polyoxyethylene chain) and having an HLB of from 7 to 12, an anionic surfactant, a protective film-forming agent, an oxidizing agent, and water.
US08864856B2 Circulating fluidized bed gasification furnace
A circulating fluidized bed gasification furnace has a combustion furnace 1, a cyclone collector 4 to which a combustion exhaust gas 3 from the combustion furnace 1 is introduced to collect a circulating medium 5, a fluidized bed gasification furnace 8 for formation of a fluidized bed 10 by introducing the circulating medium 5 collected in the cyclone collector 4 through a downcomer 7 and by supplying a gasification agent 9 from below and for gasification of a raw material 12 by supplying the same to a freeboard 11, and a circulation flow passage 14 for return of the circulating medium and unreacted char not gasified in the gasification furnace 8 to the combustion furnace 1. The downcomer 7 connected to the collector 4 has a lower end connected through a sealer 18 to the freeboard 11 in the gasification furnace 8. A raw material supply unit 20 is arranged to supply the raw material 12 to the circulating medium 5 between the sealer 18 and the freeboard 11.
US08864855B2 Portable hydrogen generator
Portable hydrogen generators are disclosed. In the various embodiments, the generator may include a chamber configured to endothermically decompose a material positioned within the chamber to generate hydrogen gas. A heater may be in thermal communication with the material to stimulate a release of the hydrogen gas. An electrical power source may be controllably coupled to the heater, so that electrical power delivered to the heater may be controlled in response to at least one detected property of the hydrogen gas.
US08864854B2 Pelletization and calcination of green coke using an organic binder
A method of calcining green petroleum coke which includes separating the green coke having a particle size of between 0.1 mm and 50 mm into undersized and oversized fractions, pelletizing the undersized fraction with a binder to form pelletized coke, combining the oversized fraction and the pelletized coke to form a feed mixture, and calcining the feed mixture to form calcined coke. The method includes the addition of a pulverization step wherein all the green coke is pulverized before pelletization and the pellets are then calcined to produce a pelletized calcined coke product.
US08864847B1 Systems and methods for preventing mobile device loss
A computer-implemented method for preventing mobile device loss may include 1) identifying historical data specifying a plurality of past locations of a plurality of mobile computing devices, 2) identifying a current location of a mobile computing device within the plurality of mobile computing devices, 3) determining that the current location deviates from an expected location based on the historical data, and 4) performing a security measure on the mobile computing device in response to determining that the current location deviates from the expected location. Various other methods, systems, and computer-readable media are also disclosed.
US08864845B2 System for control of a prosthetic device
A system for control of a prosthetic device includes at least one Inertial Measurement Unit detecting orientation of a user's foot. The at least one Inertial Measurement Unit is in communication with a device module configured to command at least one actuator of a prosthetic device. The at least one Inertial Measurement unit sends output signals related to orientation of the user's foot to the device module and the device module controls the at least one actuator of the prosthetic device based on the signals from the at least one Inertial Measurement Unit. The device module controls movement of an endpoint of the device within a movement envelope. The device module commanding movement of the end point within the movement envelope through at least simultaneous and/or independent actuation of the plurality of actuators based on the at least one body input signal in accordance with a movement function to achieve the desired directional movement of the endpoint within the movement envelope.
US08864835B2 Multi-component knee implant assembly with multiple articulating and traveling surfaces
A multi-component joint assembly incorporated into reconditioned end surfaces established between an upper bone and an opposing lower bone. A first component is anchored into the upper reconditioned bone end surface and exhibits a first exposed support surface, a second component is anchored into the lower reconditioned bone end surface and exhibits a second exposed support surface. A spherical shaped and multi-directional supporting component is supported between the first and second anchored components.
US08864834B2 Method and apparatus for fitting a shoulder prosthesis
Method and set of surgical instruments for fitting a shoulder prosthesis, and the shoulder prosthesis. The proposed method seeks to interpose a bone graft between the previously prepared glenoid surface (G) of a scapula (S) of a patient's shoulder and the face of a glenoid prosthetic component opposite the articular surface. The set of instruments permit the bone graft to be taken from the upper epiphysis of the humerus (H), either in situ or ex vivo.
US08864833B2 Expandable fusion device and method of installation thereof
The present invention provides an expandable fusion device capable of being installed inside an intervertebral disc space to maintain normal disc spacing and restore spinal stability, thereby facilitating an intervertebral fusion. In one embodiment, the fusion device includes a body portion, a first endplate, and a second endplate, the first and second endplates capable of being moved in a direction away from the body portion into an expanded configuration or capable of being moved towards the body portion into an unexpanded configuration. The fusion device is capable of being deployed and installed in both configurations.
US08864832B2 Posterior total joint replacement
A prosthetic system for implantation between upper and lower vertebrae comprises an upper joint component. The upper joint component comprises an upper contact surface and an upper articulation surface. The system further includes a lower joint component. The lower joint component comprises a lower contact surface and a lower articulation surface configured to movably engage the upper articulation surface to form an articulating joint. The articulating joint is adapted for implantation within a disc space between the upper and lower vertebrae, allowing the upper and lower vertebrae to move relative to one another. The system further includes a bridge component extending posteriorly from one of either the upper or lower joint components and from the disc space. The bridge component has a distal end opposite the one of the either upper or lower joint components. The distal end of the bridge component comprises a connection component adapted to receive a fastener.
US08864831B2 Fixation of elastomer to rigid structures
A surgical implant, especially an artificial intervertebral disc, includes a rigid substrate (513) having a porous attachment structure (512) that covers a portion of the substrate and an elastomeric body (510) that is fastened to the substrate by impregnating the porous attachment structure. The porous attachment structure has a net porosity greater than 21.5%. The porous attachment structure may be, for example, a perforated plate or a screen spaced from a substrate surface, or a layer of trabecular metal or an open-cellular material.
US08864828B2 Interspinous spacer
An implantable spacer for placement between adjacent spinous processes in a spinal motion segment is provided. The spacer includes a body defining a longitudinal passageway. A first arm and a second arm are connected to the body. Each arm has a pair of extensions and a saddle defining a receiving portion configured for seating a spinous process of a scoliotic spine or a spine with misaligned spinous processes. Each arm has a proximal caming surface and is capable of rotation with respect to the body. An actuator assembly is disposed inside the longitudinal passageway and connected to the body. When advanced, a threaded shaft of the actuator assembly contacts the caming surfaces of arms to rotate them from an undeployed configuration to a deployed configuration. In the deployed configuration, the distracted adjacent spinous processes are seated in the superior and inferior arms of the spacer.
US08864826B2 Integrated prosthetic element
Integrated prosthetic element usable for bone implant operations or as a bone filler or replacement, comprising at least a metal support and an insert made of plastic material coupled with at least a first surface of said metal support so as to define a wear surface, or insert, of adjustable thickness. The metal support comprises, on the side opposite said first surface, a second surface intended to be coupled with the bone part on which the prosthesis or bone replacement is installed. The first surface comprises a layer having cavities or holes distributed in a substantially uniform manner and suitable for anchorage and solidarization of the plastic material that makes up the insert, while said second surface comprises a porous layer suitable to optimize the bone anchorage. The first surface and the second surface are separated by a compact layer that stops the plastic material in the step of forming the plastic insert. The cavities or holes of the first surface have bigger shapes and sizes than, and in any case different from, the pores of the second surface.
US08864822B2 Devices and methods for introducing elements into tissue
Systems, devices and methods for securing tissue including the annulus of a mitral valve. The systems, devices and methods may employ catheter based techniques and devices to plicate tissue and perform an annuloplasty.
US08864816B2 Implantable medical devices incorporating x-ray mirrors
An implantable medical device includes a radiolucent member provided with an x-ray mirror that reflects incident x-ray radiation to enable visualization of the device. The x-ray mirror includes a multilayer nanolaminate having alternating layers of a first metal or ceramic layer deposited by atomic layer deposition having a first refractive index, and a second metal or ceramic layer deposited by atomic layer deposition having a second refractive index that is different from the first refractive index. The nanolaminate includes a total of at least four layers.
US08864815B2 Medical devices including metallic film and at least one filament
Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The medical device can include a composite cover formed of a deposited metallic film. The cover may include one or more filaments, e.g., wires, which cooperate with the film to provide desirable mechanical properties. The wires may be integrated with the film by depositing the film over the wires.
US08864812B2 Branched stent delivery system
An interventional delivery system with a first catheter having at its distal end a side branch vessel segment; a second catheter attached around the first catheter and having at its distal end a main vessel segment; a side branch vessel device attached to side branch vessel segment of the first catheter; and main vessel device attached to the main vessel segment of the second catheter. The main vessel device and the side branch vessel device are able to be simultaneously delivered to a treatment site.
US08864804B2 Bent dip fusion screw
Devices and methods are disclosed for the fusion of joints (particularly finger joints or toe joints) in a bent (or angled) position. In certain embodiments, the device is pre-bent and inserted into the joint in its pre-bent configuration. Alternatively, the device may be configured to have a first position wherein it is bent and a second position wherein it is straight. In that case, the device is preferably straightened by inserting a K-wire through a cannula in the device, and the device can be inserted into the joint in its straight position. Once inserted, the device is permitted to move to its bent position, which moves the joint to a bent position. In one embodiment the device moves to its bent position when the K-wire is removed.
US08864789B2 Interventional medical device system having a spiral section and radiopaque marker and method of making the same
A system is provided that includes an elongated introducer navigable through body vessels of a human subject and a pusher component for incorporation within the introducer. The pusher component includes a tubular portion with a spiral ribbon. A radiopaque marker is secured to at least a portion of the spiral ribbon such that an outer surface of the radiopaque marker is substantially flush with an outer surface of the tubular portion immediately proximal and/or immediately distal the radiopaque marker. According to a method of manufacturing such a component, the spiral ribbon is formed by a spiral cutting operation and a pre-assembly radiopaque marker member is crimped onto the spiral ribbon. According to another method of manufacturing such a component, the spiral ribbon is formed by winding a filament and a pre-assembly radiopaque marker member is crimped onto the spiral ribbon.
US08864787B2 Ethmoidotomy system and implantable spacer devices having therapeutic substance delivery capability for treatment of paranasal sinusitis
Substance delivering spacer devices may comprise expandable reservoirs that are implantable in paranasal sinuses and other cavities, openings and passageways of the body to maintain patency and to provide sustained local delivery of a therapeutic or diagnostic substance. Also provided are sinus penetrator devices and systems for performing ethmoidotomy procedures or for creating other openings in the walls of paranasal sinuses or other anatomical structures.
US08864785B2 Method for securing vertebrae
A surgical access system for accessing a surgical target site within a spine includes a retractor and an elongated element. The retractor has a closed configuration defining a lumen with an internal circumference, and an open configuration in which the internal circumference, at least at the distal end of the retractor, is enlarged relative to said closed configuration. The open configuration creates and maintains an operative corridor to said target site. The elongated element is releasably coupled to an interior wall of the retractor and has an extension extending distal of the distal end of the retractor into the surgical target site. When coupled to the retractor, the elongated element covers a body structure at the target site without blocking access to the operative corridor.
US08864782B2 Ophthalmic marking device
An ophthalmic marker having a U-shaped yoke at one end of a cranked axle is disclosed. The axle is rotatable mounted with a co-axial cylindrical handle. The other end of the axle extends beyond the handle and is bifurcated. A plumb bob having a sphere and a stem is pivotally mounted on the bifurcated end of the axle. The yoke has three marker points the upper two of which are maintained in a horizontal plane by a gravitational force urging the plumb bob into a vertical plane notwithstanding the handle not being held exactly horizontal. A method of eye marking and marker making are also disclosed.
US08864775B2 Applying forceps for a clip
An applying forceps for a clip comprises two forceps legs which can be pivoted relative to each other and comprise, on their sides facing each other or facing away from each other, each a depression or a projection for receiving a clip, wherein the depression or projection extends along an arcuate curve.
US08864773B2 Devices and methods for treating vertebral fractures
The present application is directed to devices and methods for treating vertebral fractures with one or more bone pins. In one embodiment of a method, a fractured vertebral body may be accessed through a pedicle portion and an opening may be created therethrough. One or more bone pins may be inserted through the opening. In one embodiment, at least one of the inserted bone pins is inserted to extend across a fracture zone with a proximal portion of the pin engaging a first bone segment and a distal portion engaging a second bone segment. The pin or pins may be manipulated to immobilize the first and second portions of the fractured vertebra.
US08864766B2 Kerrison rongeurs
A Kerrison rongeur employing a shearing/cutting or grasping mechanism, and suited for specific cutting and sampling bone, cartilage and soft tissue. A slideable upper member has on its advancing face a cutting element that moves past an opposing cutting element on a stationary footplate to produce a shearing action of tissue positioned within the jaws. The cutting element of the slideable member may move past the stationary member on the outside in an overbite situation or on the inside in an underbite situation. A hybrid over/underbite jaw is also contemplated along with a guillotine cutting element and a textured grasping element. In operation, the tissue is placed between the jaw and footplate, and the former is advanced towards the latter to cut and/or grasp and remove for a surgical site.
US08864765B2 Kit for reconditioning femur and ilium bones in preparation for installation of a joint implant
A hip implant assembly including a ball and stem. An annular rim separates the ball from the stem and abuts over an exterior reconditioned surface of the femur upon inserting the stem within an interior femur passageway. A cup shaped support seats the ball in articulating fashion via a ligament which extends from the ball and is received within a recess passageway of the cup. The cup includes a mounting surface with a central projecting portion which in turn resistively fits within an undercut recess formed in the ilium bone in communication with a base surface of the reconditioned acetabulum socket. An installation kit assists the preparation of the femur and ilium bones, as well as the installation of the implant body into the conditioned femur end and the cup outer socket support to a reconditioned acetabulum defined in the ilium bone.
US08864764B2 Osteosynthesis clip and insertion tool for use with bone tissue fragments
An osteosynthesis clip for the cicatrization of bone tissue fragments and an insertion tool for inserting the clip are provided. The clip includes at least two engagement legs extending approximately parallel to one another and including respective distal bridging tips and respective proximal insertion tips to be inserted into the bone tissue fragments; and a connecting bridge coupled to the distal bridging tips of the two engagement legs, the connecting bridge including at least two elongated sections extending along side one another, the elongated sections extending along a non-linear trajectory to form a non-linear deformable region, such as a depression or a dome.
US08864762B2 Balloon catheter mesh
A resector balloon includes an outer wall having a resecting surface that resects biological material. The balloon also includes a woven sleeve including at least one woven thread disposed on at least a portion of the outer wall. The woven sleeve forms at least a portion of the resecting surface. In certain embodiments, the woven sleeve includes weft knit threads including crossover points where the threads overlap. In some embodiments, the woven sleeve includes electrically conductive threads.
US08864761B2 System and method for determining proximity relative to a critical structure
A system for determining proximity of a surgical device relative to an anatomical structure includes at least one surgical device having a sensor assembly operably coupled to a processing unit. The sensor assembly is configured to transmit at least one electrical signal through the target anatomical structure to elicit a measurable response from the target anatomical structure. The processing unit is configured to calculate a signature property value of the target anatomical structure based on the measurable response and to determine proximity of the at least one surgical device relative to the target anatomical structure based on a comparison between the signature property value and at least one other signature property. An indicator is operably coupled to the processing unit and is configured to alert a user of the identified target anatomical structure based on the determined proximity.
US08864758B2 Catheter design that facilitates positioning at tissue to be diagnosed or treated
A catheter used for diagnosing and treating, for example, atrial fibrillation. The catheter includes a catheter shaft that has a proximal portion and a distal portion. The distal portion is adapted to be inserted into a body cavity having tissue to be diagnosed or treated and is disposed remotely from the proximal portion. The distal portion, which may be curved or straight, comprises an outer peripheral wall having an active region, and the distal portion has a cross-sectional configuration along the active region. The cross-sectional configuration is adapted to bias the active region against the tissue to be diagnosed or treated.
US08864757B2 System and method for measuring force and torque applied to a catheter electrode tip
A contact sensing assembly including a catheter including an electrode having a base portion mounted adjacent a head portion of the catheter body. A sensor is disposed adjacent the base portion for measuring compression or tensile forces applied to an electrode tip portion, and includes a predetermined sensitivity. The base and head portions include predetermined rigidity so that forces applied to the electrode tip portion are determinable as a function of the sensitivity and a sensor output. A contact sensing assembly also includes an electrode pipe operatively connected to the catheter body for movement and bending with the catheter body, and an electrode wire disposed in the electrode pipe and including insulation. A change in capacitance resulting from movement of the electrode wire toward the electrode pipe or contact of the electrode wire with the electrode pipe during bending of the catheter correlates to a force applied to the catheter.
US08864755B2 Device and method for endovascular treatment for causing closure of a blood vessel
An endovascular treatment method for causing closure of a blood vessel is provided. The method includes inserting into a blood vessel an optical fiber having a core through which a laser light travels and a spacer sleeve arranged around a distal portion of the core. A distal end of the core defines an enlarged light emitting face, which advantageously provides substantially lower power density while providing the same amount of total energy during a treatment session. After the insertion, laser light is applied through the light emitting face while the inserted optical fiber and spacer sleeve are longitudinally moved. The spacer sleeve positions the light emitting face away from an inner wall of the blood vessel and application of the laser light causes closure of the blood vessel.
US08864751B2 Control system for reducing internally generated frictional and inertial resistance to manual positioning of a surgical manipulator
A robotic control system is placed in clutch mode so that a slave manipulator holding a surgical instrument is temporarily disengaged from control by a master manipulator in order to allow manual positioning of the surgical instrument at a surgical site within a patient. Control systems implemented in a processor compensate for internally generated frictional and inertial resistance experienced during the positioning, thereby making movement more comfortable to the mover, and stabler from a control standpoint. Each control system drives a joint motor in the slave manipulator with a saturated torque command signal which has been generated to compensate for non-linear viscous forces, coulomb friction, cogging effects, and inertia forces subjected to the joint, using estimated joint angular velocities, accelerations and externally applied torques generated by an observer in the control system from sampled displacement measurements received from a sensor associated with the joint.
US08864749B2 Surgical instrument
A surgical instrument includes a surgical section that performs a predetermined procedure on a target organ in a body cavity, and an insertion section that includes an active movable section and a switchable tube section, the active movable section being provided with the surgical section at a top end of the active movable section, and the switchable tube section being selectively switchable between a pliable state and a rigid state.
US08864744B2 Medical device having laminate-coated braid assembly
A catheter includes a braid assembly having a dual-laminate coating. The braid assembly includes a plurality of braid members interwoven to provide for interstices between the braid members, each braid member having an electrically conductive element, a flexible non-electrically-conductive polymer coating that insulates the electrically conductive element and a thermoplastic bonding adhesive coating. The braid assembly is formed between an inner polymer layer and an outer polymer layer. One or more of the braid members may be coupled to an energy delivery element.
US08864741B2 Varicose vein treatment
Methods for treating an undesired varicose or spider vein in a venous system of a patient generally includes substantially emptying the vein of blood between its proximal end and distal end; introducing a medically acceptable adhesive into the substantially emptied vein; and applying pressure to the vein to cause the opposing side walls of the vein to be adhered together in a collapsed configuration by the adhesive. Also disclosed are kits for the treatment of undesired varicose or spider vein in a venous system of a patient. The kits include a medically acceptable adhesive; a cannula; a guide wire; and a catheter.
US08864740B2 Needle assembly with release mechanism
A needle assembly comprises a body configured for attachment to a drug delivery device. The body defines a cavity. A septum is positioned within the cavity and a stopper positioned within the cavity such that the cavity, septum, and stopper define a reservoir. A double ended needle is positioned in the stopper and septum, the needle comprising a proximal end and a distal end. A release mechanism is positioned near a distal end of the body. A biasing element is positioned to drive the stopper. During a dose dispensing step, the release mechanism drives the proximal end of the needle out of the septum so that the proximal end resides in said reservoir. The biasing element may also drive the stopper proximally.
US08864739B2 Methods and apparatuses for detecting occlusions in an ambulatory infusion pump
An improved pump, reservoir and reservoir piston are provided for controlled delivery of fluids. A motor is operably coupled to a drive member, such as a drive screw, which is adapted to advance a plunger slide in response to operation of the motor. The plunger slide is removably coupled to the piston. Methods, systems, and articles of manufacture for automatically detecting an occlusion in a medication infusion pump are provided. The electrical current to an infusion pump may be measured. Based on measurements of one or more variables, such as force, the infusion pump detects whether there is an occlusion in the system. The methods of detecting occlusions may be dynamic.
US08864738B2 Devices and methods for agent-assisted medical procedures
Various embodiments of bulking or cushioning agents or material and related medical devices and methods are disclosed. For example, a method of performing a medical procedure in a tract of a body may include injecting a material in a liquid phase proximate a target site between a first tissue layer and a second tissue layer, allowing the material to transition from the liquid phase to the gel phase in response to a raise in temperature of the material to approximately at or above the predetermined temperature, and performing a surgical procedure on the target site. The material may have the liquid phase at temperatures below a predetermined temperature and a gel phase at temperatures approximately at or above the predetermined temperature.
US08864732B2 Tampon
A tampon suitable for feminine hygiene and/or medical purposes having a longitudinal body provided with a dome-shaped insertion end and a withdrawal end, from which a withdrawal cord extends is disclosed. The tampon is made of compressed absorbent fibrous material and has an outer circumferential surface which is at least partially provided with longitudinal grooves that are separated from each other by longitudinal ribs. The path of the grooves and the ribs in the longitudinal direction of the tampon correspond to a continuous curved line that has only one point of inflection defining one convex part and one concave part, and that preferably does not show a maximum and/or a minimum.
US08864729B2 Ostomy closure
Ostomy ports with self closing for prevention of undesired waste leakage which changing bags or covering and uncovering of a port. A valve may be automatically activated by uncovering of the port. Optionally or alternatively, a valve may be automatically opened by covering of the port.
US08864728B2 Multi-conduit manifolds, systems, and methods for applying reduced pressure to a subcutaneous tissue site
The illustrative embodiments described herein are directed to systems, methods, and apparatuses for applying a reduced pressure to a subcutaneous tissue site. In one instance, a manifold for applying reduced pressure to a subcutaneous tissue site includes a plurality of first conduits, each of the plurality of first conduits having a wall with at least one first aperture and at least one second aperture. At least one of the plurality of first conduits is operable to deliver reduced pressure to the subcutaneous tissue site. The plurality of first conduits is coupled in a spaced arrangement that forms an interior space. The manifold further includes a second conduit comprising the interior space and formed by a portion of each wall of the plurality of first conduits. The second conduit is in fluid communication with the plurality of first conduits via the at least one second aperture.
US08864727B2 Transdermal delivery system, method for manufacturing the same, and transdermal delivery method using the system
Disclosed is a transdermal delivery system of multiple adhesive layers having a drug-free adhesive layer as an intermediate layer to control drug delivery rate. The transdermal delivery system enhances transdermal delivery rate in the early stage after application on skin and provides sustained control of the drug delivery rate in the intermediate and later stages. Thus, the drug delivery rate effective for treatment can be controlled in a sustained manner.
US08864726B2 Pressure vented fluid reservoir having a movable septum
Disclosed herein is a fluid infusion device of the type that delivers medication fluid to the body of a patient. The device includes or cooperates with a fluid reservoir, and the device has a sealing assembly to receive and form a fluid seal with the fluid reservoir. A retractable sealing element surrounding a hollow fluid delivery needle may be used to seal a port of the fluid reservoir. The port may include a pressure vent that is sealed by the retractable sealing element. In one variation, the reservoir includes a moving valve sleeve that holds a septum. The septum moves to allow the reservoir to vent, and to form a seal with the port when the needle pierces the septum. In another variation, the device includes a needleless sealing assembly. In yet other variations, the device uses a needled fluid reservoir.
US08864725B2 Hazardous drug handling system, apparatus and method
A system is provided for use and handling a medical liquid (e.g. hazardous drugs) that includes a transfer adapter having a port rotatably interconnectable to a male luer fitting of a needleless syringe or infusion tubing line port, and a patient connector having a port rotatable interconnectable to a female luer fitting of an intravascular catheter access port. Ports of the transfer adapter and patient connector are interconnectable to automatically define a closed fluid passageway. A vial adapter and/or a reservoir adapter may be provided for selective interconnection to the transfer adapter wherein a second closed fluid passageway and/or a third closed fluid passageway are automatically defined upon interconnection with the transfer adapter. The features may be included with restrict disconnection of the transfer adapter from the male luer fitting after initial connection therewith which restricts disconnection of a vial adapter after initial interconnection therewith and/or which restricts disconnection of a reservoir adapter from a fluid reservoir after initial connection therewith. Various methods are provided which utilize one or more of the noted components.
US08864724B2 Catheter with valve
A catheter including one or more bidirectional valves is provided. The catheter includes a tubular body having proximal and distal ends, and inner and outer surfaces, and at least one valve formed near the distal end of the tubular body. The valve includes a deformation portion that defines a slit that is openable and closable. The openable/closable slit communicates from the inner surface to the outer surface of the tubular body, wherein the distance between the inner surface and the outer surface of the tubular body progressively becomes thinner approaching the openable/closable slit within the deformation portion.
US08864720B2 Dose setting element for a drug delivery device and drug delivery device with dose setting element
The invention relates to a dose setting mechanism (1) for a drug delivery device (2), comprising a number of separate dose setting elements (3.1 to 3.n), wherein a dose volume and/or a dose number are/is set by moving at least one of the respective dose setting elements (3.1 to 3.n) from a stack position (I) to an initial position (II), and wherein a medicament dose volume is applied by moving at least one dose setting element (3.1 to 3.n) from the initial position (II) to a dispense position (III) and wherein the movement of the dose setting element (3.1 to 3.n) from the initial position (II) to the dispense position (III) is limited by at least a height (h) of the dose setting elements (3.1 to 3.n) in the initial position (II), wherein each dose setting element (3.1 to 3.n) comprises a plurality of bulges (B1 to Bm) on at least one surface side (S1), wherein the height (h) of each dose setting element (3.1 to 3.n) equals a sum of the thickness (D) of the dose setting element (3.1 to 3.n) and the bulge height (h1).
US08864719B2 Medical cartridge receiver having access device
A needle and receiver assembly for use with a syringe cartridge filled with medicine includes a cartridge receiver having a hollow interior, an open end sized for receiving at least part of the syringe cartridge, and a closed end opposite the open end. The assembly includes a needle mounted on the receiver having a fluid passage extending between a sharp delivery tip at a distal end of the needle and a sharp access tip at a proximal end of the needle opposite the delivery tip positioned inside the hollow interior of the receiver. The assembly includes a cutter movably mounted in the hollow interior of the receiver for movement relative to the receiver and the needle to cut the diaphragm of the cartridge when received in the hollow interior of the receiver.
US08864715B2 Assembly method for catheter with blood control
A system and method for assembling a catheter device, wherein a septum actuator is positioned within the lumen of a catheter adapter to provide a pathway through a septum component, an introducer needle being inserted through the septum via the septum actuator thereby preventing damage to the septum, the septum actuator thereafter being withdrawn from the septum and positioned within a rearward chamber of the catheter adapter lumen.
US08864709B2 Medical liquid supply device
In a medical liquid supply device, a control unit controls a liquid supply driver so that a liquid flows from the liquid supply driver in a liquid supply path regardless of whether a liquid-supply ON mode is selected. All of the liquid flowing from the liquid supply driver flows into a communication path when the liquid-supply ON mode is not selected. At least a part of the liquid flowing from the liquid supply driver does not flow into the communication path and is thereby supplied from a distal end of the liquid supply path when the liquid-supply ON mode is selected.
US08864704B2 Medical balloon
A non-compliant medical balloon, where the non-compliant medical balloon may be changed from a deflated state to an inflated state by increasing pressure within the balloon, is made with a first fiber layer, a second fiber layer over said first fiber layer such that the fibers of the first fiber layer and the fibers of the second fiber layer form an angle and a binding layer coating the first fiber layer and said second fiber layer. The interior surface area of the non-compliant medical balloon remains unchanged when the balloon changes from a deflated state to an inflated state.
US08864703B2 Drug introduction and placement system
A drug introduction sleeve is disclosed that includes a selectively expandable body portion. The body portion is defined by a first open end and a second open end. A hollow interior is formed within the body portion. The body portion is selectively expandable from a first unexpanded configuration to a second expanded configuration whereby the volume of the hollow interior is increased when the body portion is expanded to the second expanded configuration, sufficient to temporarily retain a drug bolus.
US08864700B2 Heat exchanger and heat-exchanger-integrated oxygenator
A plurality of heat transfer pipes have a circumferential portion arranged at a short distance from an inner surface of a heat exchanger case while they are bundled to form a pipe group and a first chord which retracts toward a center in a direction of cylinder diameter from an arc formed by the circumferential portion. The plurality of bundled heat transfer pipes are loaded in the exchange case such that the first chord and an inner surface of the heat exchange case on a side where a heat exchange medium inlet port is attached are opposed to each other. By making a flow of a heat exchange medium to each heat transfer pipe uniform, a heat exchanger capable of obtaining high heat exchange performance is obtained.
US08864699B2 High citrate dialysate and uses thereof
The dose of dialysis in terms of urea clearance is marginal in many hemodialysis patients, and metabolic acidosis as determined by the pre-dialysis serum HCO3 level is common. A dialysate that included citric acid rather than acetic acid as acidifying agent provides superior performance properties. Citrate-containing dialysate was used exclusively in 22 hemodialysis patients. Initially, only 8 of the 22 patients had a pre-dialysis serum HCO3>23 mEq/L (lower limit of normal), however, after 12 weeks of dialysis using the citrate-containing dialysate, the serum HCO3 normalized in 15 patients (p=0.0001, Chi-square). Dialysis variables were kept constant in 19 of the patients, who also used and reused the same dialyzer model throughout. In these patients, the initial average urea reduction ratio (URR) was 68.5±5.9%, and after treatment with the citrate dialysate disclosed herein, this ratio had increased to 73±5.3% (p<0.03). SpKt/V, calculated using the Daugirdas II formula, also increased from 1.23±0.19 to 1.34±0.2 (p=0.01). This increased urea clearance may be the result of the anticoagulant property of citrate maintaining patency of the dialyzer membrane. The increase in pre-dialysis serum HCO3 may represent increased delivery from the dialysate and production from citric acid.
US08864695B2 Adjustable brace apparatus
An adjustable brace apparatus provides, in an exemplary embodiment, a pair of elongate wings configured for wrapping about and substantially conforming to a portion of a body of a user, an adjustment sleeve configured for slidably receiving each of the wings, and a pair of first and second tightening segments removably engagable with each of the wings and slidably engaged and suspended within the adjustment sleeve, thereby enabling the wings to substantially float and selectively overlap atop one another within the adjustment sleeve. In use, the user is able to selectively position, wrap, and engage the wings around the user's body portion, and selectively draw the wings closer against the user's body portion.
US08864693B2 Cervical collar brace with cable adjustment
A cervical collar brace including a main body collar, a first chin side support pivotally mounted to the main body collar, and a second chin side support pivotally mounted to the main body collar. A cable adjuster adjustably secures the first and second chin side supports to the main body collar and includes a rotatable wheel, one or more cables, and one or more lift effectors for lifting the chin side supports in response to rotation of the rotatable wheel in a first rotation direction. A chin piece is provided for supporting a wearer's chin.
US08864691B2 Apparatus, systems, and methods for augmenting the flow of fluid within body vessels
Apparatus, systems, and methods are sized and configured to effectively and efficiently augment the flow of fluid within body vessels, not only during conditions in which a patient is bedbound and immobile, but also in conditions when the individual is out of bed, and completely mobile and ambulatory.
US08864688B2 Probe for enteral nutrition
A probe (1) for enteral nutrition includes a tubular element (2) of elongated shape and flexible, with a first extremity (2a) having a supply mouth (4) for the introduction of nutritional substances or the like and a second extremity (2b) positionable inside the stomach of a patient and having at least a dispensing hole (6) for dispensing the nutritional substances, the tubular element (2) having a main channel (7) of communication between the supply mouth (4) and the dispensing hole (6). The probe (1) includes at least a first and a second reading element (8, 9) for reading the pressure inside the digestive system of the patient at two distinct sections of the tubular element (2).
US08864685B2 Wire guide having two safety wires
A wire guide includes a helically wound coil having a proximal end and a distal end. A mandrel is positioned within the helically wound coil and terminates before the distal end of the helically wound coil. First and second safety wires are positioned within the helically wound coil and have proximal ends attached to the mandrel and distal ends attached to the distal end of the helically wound coil. The first and second safety wires are positioned on opposite sides of a distal tip of the mandrel and have contact surfaces facing the distal tip of the mandrel that have a shape other than convex. The interaction between the mandrel tip and the safety wires during a percutaneous vascular procedure inhibit mandrel protrusion and the potential tissue damage associated therewith.
US08864684B2 Fluid diversion mechanism for bodily-fluid sampling
An apparatus includes a housing, a flow control mechanism, and an actuator. At least a portion of the flow control mechanism is movably disposed within the housing. The apparatus further includes an inlet port and an outlet port, and defines a fluid reservoir. The outlet port is fluidically coupled to a second fluid reservoir and is fluidically isolated from the first fluid reservoir. The actuator is configured to move the flow control mechanism between a first configuration, in which the inlet port is placed in fluid communication with the fluid reservoir such that the fluid reservoir receives a first flow of bodily-fluid, and a second configuration, in which the inlet port is placed in fluid communication with the outlet port.
US08864678B2 Blood pressure measuring method and blood pressure manometer
A blood pressure measuring method, according to which a pulse oscillogram of a patient is defined, the blood pressure is then determined from the pulse oscillogram and displayed. Reliable blood pressure values are obtained without additional cost to the user, by obtaining an evaluation criterion for the presence of haemodynamic stability from the individual pulse oscillogram, the determination of the blood pressure value or the determined blood pressure value being related to the criterion.
US08864677B2 Systems and methods for myocardial ischemia detection
Embodiments of the invention are related to devices and methods for myocardial ischemia detection, amongst other things. In an embodiment, the invention includes an implantable medical device including control circuitry, an electrical field sensor in communication with the control circuitry, the electrical field sensor configured to generate a signal corresponding to cardiac electrical fields. The implantable medical device can also include a chemical sensor in communication with the control circuitry, the chemical sensor configured to generate a signal corresponding to the concentration of a physiological analyte that affects cardiac electrical field waveform morphology. The control circuitry can be configured to monitor for the presence of myocardial ischemia by evaluating both the signal generated by the electrical field sensor and the signal generated by the chemical sensor. Other embodiments are also included herein.
US08864674B2 Circuit architectures and electrical interfaces for rotational intravascular ultrasound (IVUS) devices
Rotational intravascular ultrasound (IVUS) imaging devices, systems, and methods are provided. Some embodiments of the present disclosure are particularly directed to compact and efficient circuit architectures and electrical interfaces for polymer piezoelectric micromachined ultrasonic transducers (PMUTs) used in rotational IVUS systems. In one embodiment, a rotational intravascular ultrasound (IVUS) device includes: a flexible elongate member; a piezoelectric micromachined ultrasound transducer (PMUT) coupled to a distal portion of the flexible elongate member; and an application-specific integrated circuit (ASIC) coupled to the distal portion of the flexible elongate member. The ASIC is electrically coupled to the PMUT and includes a pulser, an amplifier, a protection circuit, and timing and control circuitry for coordinating operation of the pulser, amplifier, and protection circuit.
US08864670B2 Ultrasonic monitoring device for measuring physiological parameters of a mammal
An ultrasonic monitoring device includes a substrate, a plurality of ultrasonic transducer elements, a computer readable memory medium, a microprocessor, and a power source. The ultrasonic transducer elements are coupled to the substrate. Each ultrasonic transducer element is separately configured to transmit a signal to a target area of a mammal and to receive an echo return signal from the target area. The computer readable memory medium includes program instructions. The microprocessor is coupled to the ultrasonic transducer elements and to the computer readable memory medium for executing the program instructions to determine a physiological parameter of the mammal based on a combined analysis of the echo return signals received by the ultrasonic transducer elements. The power source is coupled to at least one of the ultrasonic transducer elements, the computer readable memory medium, or the microprocessor for supplying electrical energy.
US08864669B2 Method and system for tissue imaging and analysis
A method for detecting abnormal tissue in a region of healthy tissue, comprising: a) making a first measurement of ultrasound backscattered from the region; b) heating the region, at least after the first measurement; c) making one or more additional measurements of ultrasound backscattered from the region after some or all of the heating; and d) analyzing the measurements to detect the abnormal tissue by finding differences in changes, caused by the heating, of one or more characteristics of ultrasound backscattering, between the abnormal tissue and the healthy tissue.
US08864666B2 Wireless flow sensor
Devices and methods useful for non-invasively measuring and indicating a rate of fluid flow are disclosed. In one embodiment, a sensor housing adapted to received fluid flow therethrough is provided. A radio frequency tag and a masking element can be disposed in the sensor housing. The masking element and the radio frequency tag can be configured to move relative to one another. The relative positions or movement can alter the response of the radio frequency tag to a wireless signal (which can be emitted from an external reading device, for example) and thereby indicate a rate of fluid flowing through the housing. For example, in some embodiments, the masking element can selectively cover at least part of the radio frequency tag in correspondence to the flow rate, which can change a characteristic of the radio frequency tag's response to the wireless signal.
US08864662B2 Cyclo olefin polymer and copolymer medical devices
Medical retractors including light guides made of cyclo olefin polymer.
US08864659B2 Seal anchor for use in surgical procedures
A surgical apparatus for positioning within a tissue tract accessing an underlying body cavity, includes a seal anchor member comprising a compressible material and being adapted to transition between a first expanded condition to facilitate securing of the seal anchor member within the tissue tract and in substantial sealed relation with tissue surfaces defining the tissue tract and a second compressed condition to facilitate at least partial insertion of the seal anchor member within the tissue tract. The seal anchor member defines a central longitudinal axis and has leading and trailing ends. At least one longitudinal object port extends between the leading and trailing ends and is adapted for reception of a surgical object whereby compressible material defining the at least one longitudinal object port is adapted to deform to establish a substantial sealed relation with the object. The seal anchor member includes at least two separable anchor segments dimensioned to be positioned in adjacent stacked relation to selectively alter the longitudinal length of the seal anchor member to accommodate tissue tracts of different lengths.