Document Document Title
US08816027B2 Catalysts and methods of use thereof to produce vinyl terminated polymers
This invention relates to a homogenous process for making a vinyl terminated propylene polymer, wherein the process comprises: contacting, propylene, under polymerization conditions, with a catalyst system comprising an activator and at least one metallocene compound, where the metallocene compound is represented by the formula: where: M is hafnium or zirconium; each X is a group bound to M as described herein; each R1 and R2 is, independently, a C1 to C10 alkyl group; each R3 is, independently, hydrogen; each R4, R5, and R6, is, independently, hydrogen or a substituted or unsubstituted hydrocarbyl group, a heteroatom or heteroatom containing group; T is a bridging group as described herein; and further provided that any of adjacent R4, R5, and R6 groups may form a fused ring or multicenter fused ring system where the rings may be aromatic, partially saturated or saturated, wherein the activator comprises a non-coordinating anion.
US08816026B2 Method and apparatus for preparing polymer beads of uniform particle size by suspension polymerisation
Monomer solution and liquid solution immiscible with the monomers in the monomer solution are cocurrently jetted upwardly in a pulsating manner in a reaction vessel. Monomer droplets are allowed to rise up in a controlled and smooth manner under the dynamic forces exerted by differential flow rate and differential pressure between the monomer and liquid solutions and the differential densities between the monomer and liquid solutions without causing coalescence, agglomeration and breakup of the monomer droplets and to stabilize by partial polymerization of the droplets at 50-60° C. The monomer droplets flow out horizontally into a polymerization reactor and get polymerized in the polymerization reactor under agitation at 80-85° C. The polymer beads are dried at 80-100° C. and sieved.
US08816025B2 Pressure-sensitive adhesive composition
There is provided a pressure sensitive adhesive composition and a pressure sensitive adhesive. A pressure sensitive adhesive composition example of the present application can provide a pressure sensitive adhesive having, for example, a high shear resistance together with an excellent peeling property or tacking property with respect to an attachment target surface.
US08816024B2 Continuous take off technique and pressure control of polymerization reactors
A polymerization reactor system includes features for operating two or more reactors in series or parallel. The system includes a discharge line coupled to an outlet of a first polymerization reactor, a first conduit connecting the first polymerization reactor to a second polymerization reactor via the discharge line, a second conduit connecting the first polymerization reactor to a flashline apparatus via the discharge line, and a diverter valve coupling the first and second conduits to the discharge line. The diverter valve is configured to selectively open the discharge line to the first conduit and close the discharge line to the second conduit in a first valve state and to selectively open the discharge line to the second conduit and close the discharge line to the first conduit in a second valve state. The diverter valve is capable of switching between the first and second valve states.
US08816023B2 Lightweight particles and compositions containing them
Disclosed are particles that have an exterior surface coated with a thin polymeric coating, such as a coating that includes a sulfur-containing polymer. Also disclosed are compositions, such as fuel-resistant sealant and coating compositions, which include such particles. Aerospace vehicles having an aperture at least partially sealed with a sealant deposited from such a sealant composition are also disclosed.
US08816021B2 Curable composition with rubber-like properties
Low viscosity, radiation curable compositions have been developed that produce plastics with silicone rubber-like properties. These compositions have also been shown to give great adhesion to plastics. The combination of an ethylenically unsaturated oligomer with di- or polythiol compound, reactive diluents and a radical initiator will produce these properties. These materials can find use in many areas such as: Electronics packaging, displays, conformal coatings, seals, gaskets, fiber optics coatings, and golf ball coatings.
US08816019B2 Thermoplastic compositions for laser direct structuring and methods for the manufacture and use thereof
The present disclosure relates to thermoplastic compositions. The disclosed compositions comprise a polycarbonate polymer, a polysiloxane-polycarbonate copolymer, a laser direct structuring additive, and a siloxane additive. Also disclosed are methods for making the disclosed thermoplastic compositions and articles of manufacture comprising the disclosed thermoplastic compositions.
US08816015B2 Low emission polyoxymethylene
Low VOC emission polyoxymethylene and compositions and products that incorporate the polyoxymethylene are described. The polyoxymethylene is end capped with compound that can prevent degradation of the polymer and subsequent emission of VOC degradation products such as formaldehyde. The end-capped polyoxymethylene can include an inorganic linkage within the polymer backbone that is the reaction product of a terminal hydroxyl group of the polyoxymethylene and a hydrolyzable group of the compound. Also disclosed are products as may be formed from the low VOC emission polyoxymethylene.
US08816010B2 Automotive material with excellent flow, high stiffness, excellent ductility and low CLTE
Composition having a melt flow rate MFR2 (230° C.) in the range of 10 to 50 g/10 min. said composition comprises two heterophasic polypropylenes comprising a propylene homopolymer matrix and an elastomeric copolymer, a plastomer and a mineral filler, wherein—said two heterophasic polypropylenes have different melt flow rates, —the first heterophasic polypropylene has a melt flow rate MFR2 (230° C.) in the range of 3.0 to 30.0 g/10 min and—the second heterophasic polypropylene has a xylene cold soluble (XCS) content in the range of 7.0 to 20.0 wt.-%.
US08816009B1 Method of making functionalized elastomer
The present invention is directed to a method of making a functionalized elastomer, comprising the steps of polymerizing at least one diene monomer and optionally a vinyl aromatic monomer in the presence of an initiator of formula (II) to produce a protected hydroxyl end-terminated polymer where R1, R2, R3 can all be the same or different and are selected from the group consisting of alkyls having from 1 to 8 carbon atoms, cycloalkyls having from 3 to 11 carbon atoms, or aryls having from 6 to 14 carbon atoms, R4 is an alkylene having from 1 to 8 carbon atoms, a cycloalkylene having from 3 to 11 carbon atoms, or an arylene having from 6 to 14 carbon atoms, X is S, O or NH, and Li is lithium; de-protecting the protected hydroxyl end-terminated elastomer to produce a hydroxyl end-functionalized polymer; reacting the hydroxyl end-funtionalized polymer with a maleimido acid chloride to produce a maleimido end-functionalized polymer; and reacting the maleimido end-functionalized polymer with a thiol-terminated polymer derived from a monomer having a hydrogen bond donor site and a hydrogen bond acceptor site to produce the functionalized elastomer.
US08816003B2 High plasticization-resistant cross-linked polymeric membranes for separations
This invention involves a composition, a method of making, and an application of high plasticization-resistant chemically cross-linked polymeric membranes such as cross-linked cellulose acetate (CA) membrane. These cross-linked polymeric membranes with covalently interpolymer-chain-connected rigid networks showed no decrease in CO2/CH4 ideal selectivity under 690 kPa (100 psig) pure CO2 pressure and also no CO2 plasticization up to 3447 kPa (500 psig) pure CO2 pressure. By using the method of chemical cross-linking as described in this invention, the separation characteristics of the polymeric membranes can be decisively improved. These new cross-linked polymeric membranes can be used not only for gas separations such as CO2/CH4 and CO2/N2 separations, O2/N2 separation, olefin/paraffin separations (e.g. propylene/propane separation), iso/normal paraffins separations, but also for liquid separations such as pervaporation and desalination.
US08816002B2 Method involving 1-benzotriazolyl carbonate esters of poly(ethylene glycol)
The invention provides for preparing a polymer-active agent conjugate, the method comprising the steps of reacting an amino acid derivative with a biologically active agent under conditions to form a polymer-active agent conjugate.
US08815998B2 Modified natural rubber, production process for the same and rubber composition and tire prepared by using the same
After hydrolyzing a phospholipid bonded to a molecular end of a natural rubber, a compound having a polar group reacting with a hydroxyl group is condensed with a hydroxyl group contained in the phospholipid-hydrolyzed natural rubber to thereby obtain a modified natural rubber in which a polar group is present at a molecular end. The modified natural rubber thus obtained in which a polar group is present at a molecular end is used for a rubber component of a rubber composition, whereby a rubber composition in which carbon black and silica as fillers are bonded to the rubber component to enhance a reinforcing effect and which is excellent in a low hysteresis loss property and abrasion resistance to a large extent is obtained. An enzyme or an alkali is used for hydrolyzing the phospholipid, and a condensing agent is used for condensing the polar group-containing compound.
US08815993B2 Polyester resin composition
A polyester resin composition comprises (A) about 100 parts by weight of polyester resin with a melting point greater than about 200° C. and including repeat units of Formula 1; (B) about 0.1 to about 80 parts by weight of white pigment; and (C) about 0.01 to about 80 parts by weight of filler. The polyester resin composition of the present invention does not exhibit deteriorated reflectance and impact strength and also has good heat resistance, non-yellowing property and humidity resistance and can be used in a light emitting diode (LED) reflector.
US08815991B2 Composition of polymers derived from renewable resources
The present invention relates to a polymer composition comprising polylactide and, based on the weight of this polymer, from 17 to 25 wt % of a chain modifier, from 30 to 55 wt % of an elastomeric polymer and from 20 to 45 wt % of a plasticizer. The invention also relates to the method of preparing said composition as well as to the method of manufacturing an article starting from said composition and the article per se.
US08815988B2 Resin compound, resin composition, and resin-molded product
A resin compound includes a reaction product of (A) aliphatic polyester and/or aliphatic polyamide and (B) an aromatic compound of which a compositional ratio is from 0.1 part by weight to 5 parts by weight with respect to 100 parts by weight of the (A) and which is represented by the following Formula (1), (X)—(CH2OH)n  Formula (1) wherein in Formula (1), X represents an n-valent group having one or more aromatic rings, and n represents an integer of from 2 to 10.
US08815987B2 Polypropylene mineral compound with reduced volatiles
Use of an inosilicate in a polymer composition to accomplish a headspace emission of all volatiles together of said polymer composition of equal or below 120 μgC/g.
US08815984B2 Elastomeric compositions with improved heat resistance, compression set, and processability
An elastomeric composition containing a rubber polymer, an acid acceptor, and a silane-modified needle-like/acircular mineral additive. Compositions according to the present invention have superior heat resistance, compression set resistance, and improved processability (lower compound Mooney) compared to known rubber compositions.
US08815980B2 Ink composition for inkjet recording, inkjet recording method and printed material obtained by inkjet recording
The invention provides an ink composition for inkjet recording, including: a component (A) that is a compound having two or more groups each of which having a specific structure; a component (B) that is at least one selected from the group consisting of organic solvents each of which having a specific structure; and (C) a colorant.
US08815978B2 Process for modifying natural rubber, and modified natural rubber
A process for modifying natural rubber and modified natural rubber with improved processing performance. The process for modifying natural rubber includes at least the following process steps: comminuting the natural rubber in a first process step; blending and purifying the natural rubber in a second process step; further comminuting the natural rubber in a third process step; and, drying the natural rubber in a fourth process step. The modified natural rubber is modified by at least four process steps.
US08815976B2 Humic substances-based polymer system
A system for use in forming polymer compositions, including as a replacement for phenolic based resin systems, for instance, in preparing foundry molds. In a preferred embodiment, the system includes the use of a) a polyermizable hydroxyl-containing component comprising a humic substance (as can be provided by lignite), b) an isocyanate component, and c) a catalyst, and preferably amine catalyst, component adapted to catalyze the polymerization of a) and b). The system is optionally used as binder system in the presence of a filler, such as, in combination with a foundry aggregate such as sand. A polymer system of this invention can be substantially free of formaldehyde or phenol, and preferably contains little or no aromatic solvents.
US08815975B2 Cyanoacrylate tissue adhesive formulations with multipurpose rheology modifiers
Absorbable and non-absorbable cyanoacrylate tissue adhesive/sealant formulations include at least one multipurpose carboxylic, acid-bearing C-succinylated polymeric rheology modifier capable of increasing the viscosity of the liquid formulation, while controlling the anionic polymerization of the cyanoacrylate monomers and increasing the compliance of the cured solid adhesive.
US08815973B2 Cement products and methods of making and using the same
Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component and a second component. The first component comprises a polymerizable resin comprising ethylenic unsaturated double bond, a suitable glycidyl group and/or a suitable isocyanate group. The second component includes a compound comprising more than one type of amine selected from the group consisting of primary amine, secondary amines, tertiary amines and quaternary amines. Alternatively, the second component includes a compound comprising a suitable mercapto (SH—) group, a hindered amine or a dimethylthiotoluenediamine (DMTDA). Optionally, the cement product includes a filler and/or a bioactive component to promote bone formation.
US08815965B2 Processes for recovering rubber from natural rubber latex
Processes for recovering natural rubber from an aqueous natural rubber latex that contains extractables and one or more additives and that is essentially free of lignocellulosic plant material are described. Natural rubber in the latex is separated from the water. Preferably, the amount of non-rubber extractables in the natural rubber is reduced by one or more extraction steps yielding a dried natural rubber.
US08815962B2 Low temperature sulfur tolerant tar removal with concomitant synthesis gas conditioning
A catalyst comprising NiO, a metal mixture comprising at least one of MoO3 or WO3, a mixture comprising at least one of SiO2 and Al2O3, and P2O5. In this embodiment the metal sites on the catalyst are sulfided and the catalyst is capable of removing tar from a synthesis gas while performing methanation and water gas shift reactions at a temperature range from 300° C. to 600° C.
US08815959B2 Oil-in-water emulsion composition and method for producing same
There is provided an oil-in-water emulsion composition whose continuous phase is an aqueous phase, but which has a high moisture evaporation suppressing effect and is also superior in feeling, and a method for producing the same.An oil-in-water emulsion composition containing an oily component having an inorganic value of 2500 or less, an organic value of 5000 or less and an IOB value of 0.3 to 0.5, the oil-in-water emulsion composition containing the following components (A) to (C) in an aqueous phase. (A) a polyoxyethylene alkyl or alkenyl ether having alkyl group or alkenyl group having 20 to 24 carbon atoms and an average molar number of ethylene oxide added of 1.5 to 4 (B) a polyhydric alcohol (C) a water-soluble polymer.
US08815956B2 Sweet flavor modifier
The present invention includes compounds having structural formula (I), or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of enhancing the sweet taste of compositions.
US08815948B2 High volume and alternative methods of delivering homeopathic remedies
An alternative method of delivery of homeopathic medicines by targeting delivery to the MALT's, especially of the intestinal tract and in high volumes.
US08815946B2 Inhibition of proliferation and fibrotic response of activated corneal stromal cells
Provided herein are methods of preventing a fibrotic response and/or scarring in a wound, comprising administering to a subject a composition comprising an amount of an amide or ester of an alpha-ketoalkanoic acid effective to inhibit a proliferative and/or fibrotic response in the wound. In one instance, the wound is to a subject's cornea, such as a wound resulting from refractive surgery. In one embodiment, the amide or ester of an alpha-ketoalkanoic acid is ethyl pyruvate.
US08815944B2 Pharmaceutical composition with gelling properties containing a tyrosine derivative
The present invention relates to an injectable pharmaceutical composition with gelling properties containing: -an active principle; a hydrophobic and bio-compatible organic liquid; and an organogelling substance, the molecules of which have the capacity to bind together via bonds of low energy, wherein the organogelling substance is chosen among L-tyrosine derivatives responding to the following formula (I) wherein: R1 is an alkyl group containing 1 to 3 carbon atoms, linear or branched; and R2 is a hydrophobic group chosen among aliphatic saturated or unsaturated fatty chains or aryl or arylalkyl groups. Its use as a vector for the release of active principles, as well as its process of preparation.
US08815941B2 2,3-fluorinated glycosides as neuraminidase inhibitors and their use as anti-virals
Compounds of structural formula (I) useful for the treatment or prophylaxis of viral infection, particularly viral influenza are provided Pharmaceutical preparations thereof and methods for their preparation are also described. The therapeutic effect is achieved via inhibition of viral neuraminidases, also known as viral sialidases. These neuraminidases are classified under the GH34 family of viral enzymes.
US08815936B2 Pharmaceutical formulations of resveratrol and methods of use thereof for treating cell disorders
Described is a composition for preventing or treating an oxidative stress related disease or condition in a subject. The disease or condition is characterized by the presence of excess oxidative compounds in the subject, and the composition includes a synergistic combination of therapeutically effective amounts of resveratrol to promote NAD+ synthesis in the subject; a chelating agent to reduce production of additional oxidative compounds in the subject; and an antioxidant to minimize the oxidative activity in the subject.
US08815935B2 Inhibitors of protein prenyltransferases
The present invention is directed to novel compounds. These compounds can be useful in inhibiting the activity of protein prenyltransferases including GGTase I and/or RabGGTase. The compounds can also be used as anti-cancer therapeutics including as part of methods for treating cancer, in assays, and in kits.
US08815934B2 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole and estrogen formulations
The present invention relates to new formulations containing one or more estrogens and 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole compounds which are useful as estrogenic agents, as well as pharmaceutical compositions and methods of treatment utilizing these compounds, which have the general structures below:
US08815931B2 Oral formulations for tetrapyrrole derivatives
Oral formulations and method of formulating photosensitive agents for oral administration during photodynamic therapy (PDT) and Antimicrobial photodynamic therapy (APDT) treatment are presented. The oral formulated photosensitizers show increased solubility and permeability, thus improving the bioavailability of photosensitizers at the treatment site. An orally administered photosensitizer is suitably formulated for mucosal adhesion and absorption via gastrointestinal mucosal membranes. Oral formulation provided herein use lipids and known proteins as carriers for photosensitizers by oral route. Carriers for encapsulating preselected photosensitizers include conventional liposomes, pegylated liposomes, nanoemulsions, nanocrystrals, nanoparticles, fatty emulsions, lipidic formulations, hydrosols, SMEDDS, Alpha-Feto protein (AFP), and Bovine-Serum-Albumin (BSA), fatty emulsions, hot-melt-extrudates and nanoparticles. The oral formulation, in case of a hydrophobic photosensitizer in the present invention, is stabilized using suitable surfactants/solubilizers thus preventing aggregation of the drug in the stomach and until it is absorbed in the duodenum and the small intestine. Oral formulations can be administered in the form of liquid, capsule, tablet, powder, paste or gel. Formulated drugs can be administered orally as one single dose or in multiple doses before administering PDT. In one embodiment Temoporfin (m-THPC) is used as a photosensitizer in the oral formulations. Temoporfin like many hydrophobic photosensitizers are especially suitable to be administered orally because there is no known enzyme system in the mammalian body which can metabolize Temoporfin or similar photosensitizers. Temoporfin can reach the blood system unchanged and fully active after absorption of the formulation in the gastrointestinal tract.
US08815929B2 Method and therapeutic/cosmetic topical compositions for the treatment of rosacea and skin erythema using α1-adrenoceptor agonists
The present invention is directed to the treatment of skin erythema as exhibited in rosacea and other conditions characterized by increased erythema (redness) of the skin. These conditions exhibit dilation of blood vessels due to a cutaneous vascular hyper-reactivity. In particular, the present invention is directed to a novel composition and method for the treatment of skin erythema using α1-adrenergic receptor (α1-adrenoceptor) agonists incorporated into cosmetic, pharmacological or dermatological compositions for topical application to the skin.
US08815921B2 Active substance combination based on trifluorobutinyl compounds and exhibiting nematicidal and insecticidal properties
The invention relates to novel active substance combinations consisting of heterocyclic trifluorobutenylen of formula (I), wherein X is halogen and N is 0, 1 or 2, and of known insecticide substances. Said novel active substance combinations are suitable for fighting harmful pests like insects and nematodes.
US08815916B2 Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
The present invention relates to pharmaceutical formulations comprising at least one acid-labile proton pump inhibiting agent and at least one antacid, which have improved bioavailability, chemical stability, physical stability, dissolution profiles, disintegration times, safety, as well as other improved pharmacokinetic, pharmacodynamic, chemical and/or physical properties. The present invention is directed to methods, kits, combinations, and compositions for treating, preventing or reducing the risk of developing a gastrointestinal disorder or disease, or the symptoms associated with, or related to, a gastrointestinal disorder or disease in a subject in need thereof.
US08815912B2 Wound and mucosa antiseptic based on bispyridiniumalkanes
The invention relates to an antimicrobially effective composition which comprises a) 0.001 to 1% by weight of bispyridiniumalkane, b) humectant and c) water. The composition has an osmolality of from 230 to 350 mOsmol/kg and is free from surfactant. It is used as wound and mucosa antiseptic.
US08815910B2 Compounds and methods for inhibiting phosphate transport
Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y and A are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
US08815909B2 Diaminocyclohexane compounds and uses thereof
The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are agonists, partial agonists and modulators of the NPY Y4 receptor and may be used for the treatment and prophylaxis of various diseases and conditions.
US08815907B2 Quaternary ammonium compounds useful as muscarinic receptor antagonists
The invention provides compounds of the formula: in salt or zwitterionic form or a pharmaceutically acceptable salt thereof, wherein R1-6, a, Z and Q are as defined in the specification. These compounds are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes for preparing such compounds and methods of using such compounds to, for example, treat pulmonary disorders such as chronic obstructive pulmonary disease and asthma.
US08815906B2 Tyrosine kinase inhibitors
Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.
US08815892B2 P2X7R antagonists and their use
The present application is directed to novel P2X7R antagonists that are indol-3-carboxamide or azaindole-3-carboxamide compounds, pharmaceutical compositions comprising the same and their use for the prophylactic or therapeutic treatment of diseases mediated by P2X7R activity.
US08815888B2 Forms of rifaximin and uses thereof
The present invention relates to new rifaximin forms kappa, theta, rifaximin:piperazine cocrystal 1 and rifaximin:piperazine cocrystal 2, methods of making same and to their use in medicinal preparations and therapeutic methods.
US08815887B2 Prophylactic or therapeutic method for Sjogren's syndrome
The present invention provides a prophylactic or therapeutic agent and a prophylactic or therapeutic method superior in the prophylaxis or treatment of Sjogren's syndrome. Provided are a prophylactic or therapeutic agent for Sjogren's syndrome, containing a compound represented by the formula (I): wherein each symbol is as defined in the Specification, or a pharmaceutically acceptable salt thereof, and a method for the prophylaxis or treatment of Sjogren's syndrome, including administering an effective amount of the compound represented by the formula (I) or a pharmaceutically acceptable salt thereof, to a subject in need thereof.
US08815885B2 Methods and compositions for modulating IRE1, SRC, and ABL activity
Disclosed herein are, inter alia, compositions for modulating Ire1, Src, or Abl, methods for identifying modulating activity in test compounds, and methods for treating diseases caused by the activity or inactivity of Ire1, Src, or Abl.
US08815878B1 Spiro hemiaminals for treating viral diseases
Substituted spiro hemiaminals and methods for their use in the treatment of viral diseases, including hepatitis C viral infections, are described herein.
US08815877B2 Serine/threonine kinase inhibitors
Compounds having the formula I wherein A, R1a, R1b, R2, R3, R4, R5, R6, R7, R8, Ra, Rb, X1, X2, X3 and n are as defined herein are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.
US08815874B2 Pyrazolopyrimidine derivative
The invention provides a pyrazolopyrimidine derivative of formula (I), wherein, for example, R1 represents —NR1aR1b (wherein R1a and R1b are the same or different and each is a hydrogen atom or aralkyl), R2 represents formula (Ya) [wherein k and m each represents an integer of 0-2, n represents an integer of 0-4, L represents a single bond, R5 represents halogen, R6 represents aryl, X represents —CR8 (wherein R8 represents a hydrogen atom), and R7 represents a hydrogen], R3 represents —SO2R13a [wherein R13a represents lower alkoxy, —NR13dC(═O)R13e (wherein R13d represents a hydrogen atom, and R13e represents lower alkyl)], and R4 represents a hydrogen atom, or a pharmaceutically acceptable salt thereof. The invention also provides a medicament containing the pyrazolopyrimidine derivative, as well as a method of using the pyrazolopyrimidine derivative to prevent and/or treat skin diseases.
US08815873B2 Heterocyclic amides as rock inhibitors
The present invention relates to new kinase inhibitors, more specifically ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In particular, the present invention relates to new ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease.In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including sexual dysfunction, inflammatory diseases, ophthalmic diseases and Respiratory diseases.
US08815872B2 Macrocyclics pyrimidines as aurora kinase inhibitors
Macrocyclic derivative compounds that inhibit protein kinase enzymes are disclosed along with pharmaceutical compositions comprising these compounds and methods for synthesizing the same. Such compounds have utility in the treatment of proliferative diseases resulting from unregulated and/or disturbed kinase activity such as cancers, psoriasis, viral and bacterial infections, inflammatory and autoimmune diseases.
US08815871B2 N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors
The present invention provides a pyrrolidine compound of General Formula (1) or a salt thereof, wherein R101 and R102 are each independently a phenyl group or a pyridyl group, the phenyl group or the pyridyl group may have one or more substituents selected from halogen atoms and lower alkyl groups optionally substituted with one or more halogen atoms, etc. The pyrrolidine compound or a salt thereof of the present invention is usable to produce a pharmaceutical preparation having a wider therapeutic spectrum and being capable of exhibiting sufficient therapeutic effects after short-term administration.
US08815865B2 Substituted 4-hydroxypyrimidine-5-carboxamides
The present invention relates to substituted 4-hydroxypyrimidine-5-carboxamides useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.
US08815863B2 Compounds and therapeutic use thereof for protein kinase inhibition
Novel compound having the following formula: (I) wherein Y is N, O, or S. Also disclosed are a pharmaceutical compositions comprising the same, methods for treating cancer using the same, and methods for the synthesis of the same. The novel compounds of the present invention are found to inhibit protein kinases, especially Checkpoint kinase Chk1/Chk2.
US08815861B2 N-(imidazolidin-2-ylidene)quinoline derivatives as modulators of alpha 2 adrenergic receptors
The present invention relates to novel N-(imidazolidin-2-ylidene)quinoline derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
US08815860B2 Methods for preventing oxidative stress injury of a tissue by a Folate-TEMPOL conjugate
The present disclosure is generally related to methods of preventing oxidative stress injury induced by renal ischemia-reperfusion by a Folate-TEMPOL conjugate.
US08815852B2 Carbamoyloxy arylalkan arylpiperazine analgesics
There is provided a novel carbamoyloxy arylalkanoyl arylpiperazine derivative compound having abundant racemic or enantiomeric characteristics, represented by the Formula 1, and pharmaceutically available salts or hydrates thereof. Also, there are provided a pharmaceutical composition for treating pain, anxiety or depression including an effective amount of the compound, and a method for treating pain, anxiety or depression in mammals by administering an effective amount of the compound to the mammals in need of treatment thereof.
US08815850B2 Process for preparing diaminophenothiazinium compounds
Process for preparing compounds of the diaminophenothiazinium type of formula (II) below. The products have a high degree of purity and are useful for the preparation of medicaments. In which the R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 groups having the same definition as in formula (I), and R representing a group chosen from: a phenyl or benzyl group, optionally substituted with one or more functions chosen from: a C1-C4 alkyl, a halogen atom, a C1-C4 haloalkyl and a nitro group, a linear, branched or cyclic C1-C8 alkyl group, a C1-C8 alkylamino group, a C1-C8 alkoxy group, a phenyloxy or benzyloxy group optionally substituted on the aromatic nucleus with one or more functions chosen from: a C1-C4 alkyl, a halogen atom, a C1-C4 haloalkyl and a nitro group, Z representing an atom chosen from O and S.
US08815849B2 Hetero-bicyclic derivatives as HCV inhibitors
Inhibitors of HCV replication of formula I including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein R and R′ have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HCV inhibitors, in HCV therapy.
US08815846B2 Family of antichagasics derived from imidazo[4,5-C][1,2,6]thiadiazine 2,2-dioxide
Compounds derived from imidazo[4,5-c][1,2,6]thiadiazine 2,2-dioxides, for use as a drug or pharmaceutical composition for treatment of parasitic diseases, preferably of diseases caused by parasites of the Trypanosoma genus, and more preferably for treatment of the Chagas disease. Furthermore, the invention also relates to the pharmaceutical compositions comprising said compounds.
US08815845B2 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
The present invention provides novel chemical compounds characterized as Rho kinase (ROCK) inhibitors, methods for their discovery, and their therapeutic, research, and diagnostic use. In particular, the present invention provides 1,4-benzodiazepine-2,5-dione compounds and related compounds having ROCK inhibitory activity, and methods of using such compounds as therapeutic agents to treat a number of conditions associated with ROCK activity.
US08815843B2 Compounds and methods of treating diabetes
Hydrogenated pyrido[4,3-b]indoles, pyrido[3,4-b]indoles and azepino[4,5-b]indoles are described. The compounds may bind to and are antagonists of the adrenergic receptor α2A. The compounds may also bind to and are an antagonist of the adrenergic receptor α2B; or the compounds are not antagonists of the adrenergic receptor α2B and the compounds are administered in conjunction with a second agent that reduces, or is expected to reduce, blood pressure in an individual. The compounds may find use in therapy, e.g., to regulate blood glucose level, increase insulin secretion and treat diseases or conditions that are, or are expected to be, responsive to an increase in insulin production. Use of the compounds to treat type 2 diabetes is particularly described.
US08815841B2 1,4-Oxazepines as BACE1 and/or BACE2 inhibitors
This invention relates to compounds of the formula wherein and R1 to R3 are as described herein, or to pharmaceutically acceptable salts thereof. These compounds are BACE1 and/or BACE2 inhibitors and can be used as pharmaceuticals for the therapeutic and/or prophylactic treatment of diseases such as Alzheimer's disease, diabetes, particularly type 2 diabetes, and other metabolic disorders.
US08815840B2 Carbazole and carboline kinase inhibitors
The present invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof The Formula (I) compounds inhibit tyrosine kinase activity of Jak2, thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.
US08815838B2 Aerosol fluoroquinolone formulations for improved pharmacokinetics
The present invention relates to the field of antimicrobial agents. In particular, the present invention relates to the use of aerosolized fluoroquinolones formulated with divalent or trivalent cations and having improved pulmonary availability for the treatment and management of bacterial infections of the lung and upper respiratory tract.
US08815837B2 Respiratory disease treatment
There is provided a pharmaceutical composition that is adapted for pulmonary administration by inhalation, which composition comprises a glitazone, such as pioglitazone or rosiglitazone, and one or more pharmaceutically acceptable carriers and/or excipients, and wherein the glitazone content of the composition consists of at least 95% by weight of the 5R enantiomer and less than 5% by weight of the 5S enantiomer. There is also provided a use and kit.
US08815834B2 Use of dendrimers to stimulate cell growth
The present invention relates to the use of dendrimers with monophosphonic or bisphosphonic terminations in order to stimulate the growth of cell cultures or to activate cells in culture.
US08815833B2 Stable amifostine liquid concentrate
A storage stable aqueous solution of amifostine at a pH of at least 10.0, in an amifostine concentration of about 50 to about 250 mg/l, which formulation is storage stable under refrigerated conditions.
US08815824B2 Compositions and methods for treating tumors, fibrosis, and pulmonary alveolar proteinosis
The present disclosure provides pharmaceutical compositions and methods useful for modulating angiogenesis and for inhibiting metastasis, tumors, pulmonary alveolar proteinosis, and fibrosis in a mammalian tissue. Pharmaceutical compositions and methods include inhibitors of LOXL2 expression and activity, such as shRNA targeting LOXL2.
US08815820B2 Anti viral therapy
The present invention provides a method of identifying host cell molecules which may be modulated to inhibit viral replication and method of testing antiviral compounds. In addition, the invention provides compositions, methods and medicaments for treating viral infections and/or diseases or conditions caused or contributed to by viruses.
US08815806B2 Yellow pea seed protein-derived peptides
The instant invention relates to peptides obtained from the enzymatic hydrolysis of yellow pea seed proteins that are capable of lowering the blood pressure and reducing the effects of kidney disease in a subject by inhibiting or reducing the affinity of the enzymes in the renin-angiotensin system for their substrates, specifically renin, to compositions comprising said peptides and to uses thereof.
US08815805B2 Formulations having an antagonist of α5β1 for anti-angiogenesis and cancer treatment
The teachings provided herein generally relate to a combination therapy and are directed to pharmaceutical compositions and methods for administering a combination of an α5β1 antagonist with an α2β1 antagonist to a subject. The methods are for use in inhibiting, preventing, or reversing angiogenesis, as well as in treating cancer. In some embodiments, the compositions and methods include a combined administration of VLO4 and VP12 (ECL12).
US08815803B2 Method for increasing body height comprising systemic administration of CNP-53
This invention provides a composition for increasing a body height of a patient with short stature or an individual other than patients with short stature. More specifically, the invention provides: a composition for increasing the body height of an individual comprising a guanyl cyclase B (GC-B) activator as an active ingredient, the composition being to be administered to an individual free from FGFR3 abnormality; a method for increasing the body height of an individual free from FGFR3 abnormality which comprises activating GC-B; a method for screening an agent for increasing the body height of an individual which comprises selecting an agent for increasing the body height using GC-B activity as an indication; and a method for extending a cartilage bone free from FGFR3 abnormality which comprises activating GC-B in an individual.
US08815800B2 Moisturizing composition comprising an aminopeptide mixture
The invention is directed to skin moisturizing compositions comprising an aminopeptide mixture. The composition replenishes the skins natural moisturization factor and delivers excellent sensory benefits. The composition is not unpleasantly viscous during and after application.
US08815798B2 Insulin analogues containing additional disulfide bonds
The present invention is related to insulin analogs containing additional disulfide bonds and methods of making such.
US08815791B2 Cleaning of a cooking device or appliance with a composition comprising a built-in rinse aid
The present invention discloses a method for cleaning a cooking device or appliance comprising contacting at least the cooking chamber of the cooking device or appliance with a cleaning composition comprising a sheeting polymer that provides a layer on the surfaces of at least the cooking chamber so as to afford a sheeting action in an aqueous rinse step. The sheeting polymer is selected from the group of cationic polysaccharides and maleic acid-olefin copolymers.
US08815788B2 Aerosol deodorizer
A cleaning solution includes an aqueous base, 0.1 wt % to 10 wt % of an organic acid, 0.1 wt % to 35 wt % of a surfactant, 0.1 wt % to 10 wt % of an organic ester derived from a carboxylic acid having at least 4 carbons, and 0.1 wt % to 11 wt % of an ethylene glycol ether.
US08815780B2 Platform for immobilization and observation of subcellular processes
A method of immobilizing matter for imaging that includes providing an array of nanofibers and directing matter to the array of the nanofibers. The matter is immobilized when contacting at least three nanofibers of the array of nanofibers simultaneously. Adjacent nanofibers in the array of nanofibers may be separated by a pitch as great as 100 microns. The immobilized matter on the array of nanofibers may then be imaged. In some examples, the matter may be cell matter, such as protoplasts.
US08815779B2 Transcription biomarkers of biological responses and methods
This invention provides transcription regulatory control sequences, the activity of which function as biomarkers for a variety of biological responses. This invention also provides expression constructs in which a biomarker transcription regulatory sequence is operably linked with a sequence for a reporter. Cells that comprise these expression constructs can be used in assays to identify conditions that modulate activity of the biological response.
US08815773B2 Herbicidal combination
A herbicidal suspension concentrate formulation comprising effective amount of glyphosate acid, effective amount of oryzalin and polyalkylene oxides and their copolymers such as EO/PO copolymer. Also disclosed is a process for the preparation of the herbicidal suspension concentrate formulations according to the present invention.
US08815770B2 Color-stable superabsorber
A superabsorbent produced by polymerizing a monomer mixture which comprises at least one ethylenically unsaturated monomer bearing at least one acid group, at least 0.1% by weight and at most 20% by weight, based on the total amount of ethylenically unsaturated monomers bearing at least one acid group (calculated as the free acid), of at least one alkaline earth metal salt (calculated without water of crystallization) selected from the salts of calcium, strontium or barium having been added before or during the polymerization and/or, if the polymerization is followed by a separate drying step, to the polymer before the drying, exhibits improved stability to discoloration in the course of storage under elevated temperatures and/or elevated air humidity.
US08815767B2 Mixed oxides catalysts
Mixed oxides catalysts usable in particular in the full oxidation to CO2 and H2O of volatile organic compounds (VOC), in the decomposition of nitrogen protoxide to nitrogen and oxygen and the combustion of CO, H2 and CH4 off gases in fuel cells, comprising oxides of manganese, copper and La2O3 and/or Nd2O3, having a percentage composition by weight expressed as MnO, CuO, La2O3 and/or Nd2O3 respectively of 35-56%, 19-31% and 20-37%. The oxides are supported on inert porous inorganic oxides, preferably alumina.
US08815765B2 Dispersed metal sulfide-based catalysts
The invention provides a catalyst composition, which includes an emulsion of an aqueous phase in an oil phase, wherein the aqueous phase comprises an aqueous solution containing a group 6 metal and a group 8, 9 or 10 metal. The metals can be provided in two separate emulsions, and these emulsions are well suited for treating hydrocarbon feedstocks.
US08815761B2 Catalyst mixing process and regenerator relating thereto
One exemplary embodiment can be a process for mixing catalyst in a regenerator. The process can include providing a first stream of catalyst, a second stream of catalyst mixed with the first stream of catalyst, and an oxygen-containing gas to a chamber via a distributor of the regenerator. Generally, the chamber imparts a swirl to at least one of the oxygen-containing gas, the first catalyst, and the second catalyst for regenerating the catalyst.
US08815754B2 Photoresists and methods for use thereof
New photoresists are provided that comprise preferably as distinct components: a resin, a photoactive component and a phenolic component Preferred photoresists of the invention are can be useful for ion implant lithography protocols.
US08815749B2 Method for manufacturing a barrier layer on a substrate and a multi-layer stack
A method for manufacturing a barrier layer (14) on a flexible substrate (6a, 6b), comprising depositing an inorganic layer on the substrate in a treatment space (5), the treatment space (5) being formed between at least two electrodes (2, 3) for generating an atmospheric pressure glow discharge plasma. The barrier layer (14) is characterized in that it is formed by three subsequent depositions of inorganic layers on the substrate (6a, 6b), each layer being at most 150 nm in thickness.
US08815747B2 Methods of forming patterns on substrates
A method of forming a pattern on a substrate includes forming spaced features over a substrate. A polymer is adsorbed to outer lateral surfaces of the spaced features. Either material of the spaced features is removed selectively relative to the adsorbed polymer or material of the adsorbed polymer is removed selectively relative to the spaced features to form a pattern on the substrate. In one embodiment, the polymer is of known chain length and has opposing longitudinal ends. One of the longitudinal ends of the polymer adsorbs to the outer lateral surfaces whereby the adsorbed polymer projects lengthwise from the outer lateral surfaces, with said chain length defining a substantially uniform lateral thickness of the adsorbed polymer on the spaced features. Additional embodiments are contemplated.
US08815746B2 Apparatus and method for producing microcomponents and use of
An apparatus and the use of such an apparatus and method for producing microcomponents with component structures are presented which are generated in a process chamber on a substrate according to the LIGA method for example and are stripped from the enclosing photoresist with the help of a cooled remote plasma source.
US08815736B2 Methods of forming metal silicide regions on semiconductor devices using different temperatures
Disclosed herein are various methods of forming metal silicide regions on semiconductor devices by using different temperatures during the silicidation processes. In one example, the method includes forming a plurality of N-doped source/drain regions and a plurality of P-doped source/drain regions in a semiconducting substrate and performing a first heating process at a first temperature to initially form a first metal silicide region in each of the P-doped source/drain regions. The method further includes performing a second heating process at a second temperature to initially form a second metal silicide region in each of the N-doped source/drain regions, wherein the second temperature is less than the first temperature and performing a third heating process at a third temperature to complete the formation of the first and second metal silicide regions, wherein the third temperature is greater than the first temperature.
US08815735B2 Semiconductor device and method of manufacturing the same
A semiconductor device comprises a substrate, a dielectric layer, an undoped silicon layer, and a silicon material. The substrate comprises a doped region. The dielectric layer is formed on the substrate and comprises a contact hole, and the contact hole corresponds to the doped region. The undoped silicon layer is formed on the doped region. The silicon material fills the contact hole from the undoped silicon layer.
US08815732B2 Wire bonding method and semiconductor device
After forming a pressure-bonded ball and a ball neck by bonding an initial ball to a pad, a capillary is moved upward, away from a lead, and then downward, thereby the ball neck is trodden on by a face portion that is on the lead side of the capillary. Subsequently, the capillary is moved upward and then toward the lead until the face portion of the capillary is positioned above the ball neck, thereby a wire is folded back toward the lead. Then, the capillary is moved downward such that a side of the wire is pressed by the capillary against the ball neck that has been trodden on. After the capillary is moved obliquely upward toward the lead and then looped toward the lead, the wire is pressure-bonded to the lead.
US08815730B1 Method for forming bond pad stack for transistors
A method for forming bond pads on a semiconductor die includes forming a dielectric stack including a bottom and top dielectric layer having a contact hole therethrough over a bond pad. An outer edge of the bottom dielectric layer within the contact hole extends beyond an outer edge of the top dielectric layer to define a bond pad edge. A second metal layer on a first metal layer is deposited. A first photoresist layer is formed exclusively within the contact hole. The second metal layer is wet etched to recess the second metal layer from sidewalls of the bottom dielectric layer in the contact hole. A second photoresist layer is formed exclusively within the contact hole. The first metal layer is wet etched to recess the first metal layer from the top dielectric layer. The first metal layer extends over the bond pad edge onto the bottom dielectric layer.
US08815727B2 Integrated circuit with metal and semi-conducting gate
A method for forming an integrated circuit system is provided including forming a semi-conducting layer over a substrate, forming a spacer stack having a gap filler adjacent to the semi-conducting layer and a inter-layer dielectric over the gap filler, forming a transition layer having a recess over the semi-conducting layer and adjacent to the spacer stack, and forming a metal layer in the recess.
US08815726B2 Method of manufacturing semiconductor device
A method of manufacturing a semiconductor device including forming a mask layer on a polycrystalline silicon film formed on a semiconductor substrate via an insulating film; forming a dense pattern and a sparse pattern on the mask layer to form a mask; etching the polycrystalline silicon film with the mask by controlling a temperature of the semiconductor substrate placed in an etching chamber at 50 degrees Celsius or higher, supplying an etching gas composed of a hydrogen bromide containing gas and a fluoromethane based gas into the chamber, and generating plasma in the chamber.
US08815721B2 Semiconductor device and method of manufacturing the same
A method comprising, introducing a dopant type into a semiconductor layer to define a well region of the semiconductor layer, the well region comprising a channel region, and introducing a dopant type into the well region to define a multiple implant region substantially coinciding with the well region but excluding the channel region.
US08815718B1 Vertical surround gate formation compatible with CMOS integration
A method for fabricating vertical surround gates in a semiconductor device array structure such that the processes are compatible with CMOS fabrication. The array structure includes a CMOS region and an array region. The method includes forming a polish stop layer, a plurality of patterning layers, a CMOS layer over a substrate, array pillars and array trenches. Forming the array pillars and trenches includes removing the CMOS cover layer and patterning layers. The method further includes doping portions of the substrate within the array trenches. The method includes forming vertical surround gates in the array trenches, an array filler layer to fill in the array trenches, and a CMOS photoresist pattern over the array filler layer. The method includes etching the CMOS trenches down through a portion of the substrate, such that the array pillars under the shared trench are etched to form contact holes.
US08815717B2 Vapor deposition method and vapor deposition apparatus
According to one embodiment, a vapor deposition method is disclosed for forming a nitride semiconductor layer on a substrate by supplying a group III source-material gas and a group V source-material gas. The method can deposit a first semiconductor layer including a nitride semiconductor having a compositional proportion of Al in group III elements of not less than 10 atomic percent by supplying the group III source-material gas from a first outlet and by supplying the group V source-material gas from a second outlet. The method can deposit a second semiconductor layer including a nitride semiconductor having a compositional proportion of Al in group III elements of less than 10 atomic percent by mixing the group III and group V source-material gases and supplying the mixed group III and group V source-material gases from at least one of the first outlet and the second outlet.
US08815709B2 Chemical vapor deposition with energy input
Methods of depositing compound semiconductors onto substrates are disclosed, including directing gaseous reactants into a reaction chamber containing the substrates, selectively supplying energy to one of the gaseous reactants in order to impart sufficient energy to activate that reactant but insufficient to decompose the reactant, and then decomposing the reactant at the surface of the substrate in order to react with the other reactants. The preferred energy source is microwave or infrared radiation, and reactors for carrying out these methods are also disclosed.
US08815707B2 Environmentally-assisted technique for transferring devices onto non-conventional substrates
A device fabrication method includes: (1) providing a growth substrate including a base and an oxide layer disposed over the base; (2) forming a metal layer over the oxide layer; (3) forming a stack of device layers over the metal layer; (4) performing interfacial debonding of the metal layer to separate the stack of device layers and the metal layer from the growth substrate; and (5) affixing the stack of device layers to a target substrate.
US08815701B2 Method for manufacturing semiconductor device having SOI substrate
A semiconductor device includes: a SOI substrate including a support layer, a first insulation film and a SOI layer; a first circuit; a second circuit; and a trench separation element. The SOI substrate further includes a first region and a second region. The first region has the support layer, the first insulation film and the SOI layer, which are stacked in this order, and the second region has only the support layer. The trench separation element penetrates the support layer, the first insulation film and the SOI layer. The trench separation element separates the first region and the second region. The first circuit is disposed in the SOI layer of the first region. The second circuit is disposed in the support layer of the second region.
US08815699B2 Fabrication of reverse shallow trench isolation structures with super-steep retrograde wells
Generally, the present disclosure is directed to methods for forming reverse shallow trench isolation structures with super-steep retrograde wells for use with field effect transistor elements. One illustrative method disclosed herein includes performing a thermal oxidation process to form a layer of thermal oxide material on a semiconductor layer of a semiconductor substrate, and forming a plurality of openings in the layer of thermal oxide material to form a plurality of isolation regions from the layer of thermal oxide material, wherein each of the plurality of openings exposes a respective surface region of the semiconductor layer.
US08815698B2 Well region formation method and semiconductor base
A well region formation method and a semiconductor base in the field of semiconductor technology are provided. A method comprises: forming isolation regions in a semiconductor substrate to isolate active regions; selecting at least one of the active regions, and forming a first well region in the selected active region; forming a mask to cover the selected active region, and etching the rest of the active regions, so as to form grooves; and growing a semiconductor material by epitaxy to fill the grooves. Another method comprises: forming isolation regions in a semiconductor substrate for isolating active regions; forming well regions in the active regions; etching the active regions to form grooves, such that the grooves have a depth less than or equal to a depth of the well regions; and growing a semiconductor material by epitaxy to fill the grooves.
US08815697B2 Method of fabricating semiconductor device
Provided is a method of manufacturing a semiconductor device having a capacitor. The method includes forming a composite layer, including sequentially stacking on a substrate alternating layers of first through nth sacrificial layers and first through nth supporting layers. A plurality of openings that penetrate the composite layer are formed. A lower electrode is formed in the plurality of openings. At least portions of the first through nth sacrificial layers are removed to define a support structure for the lower electrode extending between adjacent ones of the plurality of openings and the lower electrode formed therein, the support structure including the first through nth supporting layers and a gap region between adjacent ones of the first through nth supporting layers where the first through nth sacrificial layers have been removed. A dielectric layer is formed on the lower electrode and an upper electrode is formed on the dielectric layer.
US08815696B1 Disturb-resistant non-volatile memory device using via-fill and etchback technique
A method of forming a disturb-resistant non volatile memory device includes providing a substrate and forming a first dielectric thereon, forming a first strip of material separated from a second strip of material from a first wiring material, and forming a second dielectric thereon to fill a gap between the first and second strips of material. Openings are formed in the second dielectric exposing portions of the first wiring material. Filing the openings by p+ polysilicon contact material, and then an undoped amorphous silicon material, and then a metal material. A second wiring structure is formed thereon to contact the metal material in the openings. Resistive switching cells are formed from the first wiring structure, the second wiring structure, the contact material, the undoped amorphous silicon material, and the metal material.
US08815694B2 Inducing channel stress in semiconductor-on-insulator devices by base substrate oxidation
Embodiments include semiconductor-on-insulator (SOI) substrates having SOI layers strained by oxidation of the base substrate layer and methods of forming the same. The method may include forming a strained channel region in a semiconductor-on-insulator (SOI) substrate including a buried insulator (BOX) layer above a base substrate layer and a SOI layer above the BOX layer by first etching the SOI layer and the BOX layer to form a first isolation recess region and a second isolation recess region. A portion of the SOI layer between the first isolation recess region and the second isolation recess region defines a channel region in the SOI layer. A portion of the base substrate layer below the first isolation recess region and below the second isolation recess region may then be oxidized to form a first oxide region and a second oxide region, respectively, that apply compressive strain to the channel region.
US08815691B2 Method of fabricating a gate all around device
The device includes a wafer substrate including an isolation feature, a fin base embedded in the isolation feature, at least one channel disposed above the fin base, and a gate stack disposed around the channel, wherein the gate stack includes a top portion and a bottom portion of the gate stack formed by filling a cavity around the channel such that the top portion and bottom portion are aligned each other. The device further includes at least one source and one drain disposed over the fin base, wherein the channel connects the source and the drain. The device further includes the source and the drain disposed over a fin insulator disposed over the fin base.
US08815688B2 Method of manufacturing power device
A method of manufacturing a power device includes forming a first drift region on a substrate. A trench is formed by patterning the first drift region. A second drift region is formed by growing n-gallium nitride (GaN) in the trench, and alternately disposing the first drift region and the second drift region. A source electrode contact layer is formed on the second drift region. A source electrode and a gate electrode are formed on the source electrode contact layer. A drain electrode is formed on one side of the substrate which is an opposite side of the first drift region.
US08815685B2 Methods for fabricating integrated circuits having confined epitaxial growth regions
Methods are provided for fabricating integrated circuits. In accordance with one embodiment, the method includes forming a portion of a semiconductor substrate at least partially bounded by a confinement isolation material. A liner dielectric is formed overlying the confinement isolation material and is treated to passivate a surface thereof. An epitaxial layer of semiconductor material is then grown overlying the portion of semiconductor substrate.
US08815684B2 Bulk finFET with super steep retrograde well
A method for forming a fin transistor in a bulk substrate includes forming a super steep retrograde well (SSRW) on a bulk substrate. The well includes a doped portion of a first conductivity type dopant formed below an undoped layer. A fin material is grown over the undoped layer. A fin structure is formed from the fin material, and the fin material is undoped or doped. Source and drain regions are provided adjacent to the fin structure to form a fin field effect transistor.
US08815677B2 Method of processing MIM capacitors to reduce leakage current
A method for processing dielectric materials and electrodes to decrease leakage current is disclosed. The method includes a post dielectric anneal treatment in an oxidizing atmosphere to reduce the concentration of oxygen vacancies in the dielectric material. The method further includes a post metallization anneal treatment in an oxidizing atmosphere to reduce the concentration of interface states at the electrode/dielectric interface and to further reduce the concentration of oxygen vacancies in the dielectric material.
US08815675B2 Method of manufacturing nonvolatile semiconductor memory with backing wirings
A nonvolatile semiconductor memory comprises a first memory cell transistor, a second memory cell transistor, a connection layer, protrusion portions and a contact portion. The first memory cell transistor comprises a first gate electrode formed above a first channel region, and a second gate electrode formed on a side of the first gate electrode through an insulating film. The second memory cell transistor comprises a third gate electrode formed above a second channel region, and a fourth gate electrode formed on a side of the third gate electrode through an insulating film and facing the second gate electrode. The connection layer connects the second gate electrode and the fourth gate electrode. The protrusion portions are formed of a material different than that of the second and fourth gate electrodes, and are formed on both ends of the connection layer. The contact portion is formed on the connection layer.
US08815671B2 Use of contacts to create differential stresses on devices
Disclosed herein are various methods and structures using contacts to create differential stresses on devices in an integrated circuit (IC) chip. An IC chip is disclosed having a p-type field effect transistor (PFET) and an n-type field effect transistor (NFET). One embodiment of this invention includes creating this differential stress by varying the deposition conditions for forming PFET and NFET contacts, for example, the temperature at which the fill materials are deposited, and the rate at which the fill materials are deposited. In another embodiment, the differential stress is created by filling the contacts with differing materials that will impart differential stress due to differing coefficient of thermal expansions. In another embodiment, the differential stress is created by including a silicide layer within the NFET contacts and/or the PFET contacts.
US08815670B2 Preventing Fin erosion and limiting EPI overburden in FinFET structures by composite hardmask
A FinFET structure is formed by forming a hardmask layer on a substrate including a silicon-containing layer on an insulating layer. The hardmask layer includes first, second and third layers on the silicon-containing layer. An array of fins is formed from the hardmask layer and the silicon-containing layer. A gate is formed covering a portion but not all of a length of each of the array of fins. The portion covers each of the fins in the array. The gate defines source/drain regions on either side of the gate. A spacer is formed on each side of the gate, the forming of the spacer performed to remove the third layer from portions of the fins in the source/drain regions. The second layer of the hardmask layer is removed from the portions of the fins in the source/drain regions, and the fins in the source/drain regions are merged.
US08815669B2 Metal gate structures for CMOS transistor devices having reduced parasitic capacitance
A method of forming a field effect transistor (FET) device includes forming a gate structure over a substrate, the gate structure including a wide bottom portion and a narrow portion formed on top of the bottom portion; the wide bottom portion comprising a metal material and having a first width that corresponds substantially to a transistor channel length, and the narrow portion also including a metal material having a second width smaller than the first width.
US08815662B2 Method for manufacturing SOI substrate and semiconductor device
An amorphous semiconductor layer is formed over a first single crystal semiconductor layer provided over a glass substrate or a plastic substrate with an insulating layer therebetween. The amorphous semiconductor layer is formed by a CVD method at a deposition temperature of higher than or equal to 100° C. and lower than or equal to 275° C. with use of a silane-based gas not diluted. Heat treatment is performed so that the amorphous semiconductor layer solid-phase epitaxially grows. In such a manner, an SOI substrate including a thick single crystal semiconductor layer is manufactured.
US08815659B2 Methods of forming a FinFET semiconductor device by performing an epitaxial growth process
A method of forming a FinFET device involves performing an epitaxial growth process to form a layer of semiconducting material on a semiconducting substrate, wherein a first portion of the layer of semiconducting material will become a fin structure for the FinFET device and wherein a plurality of second portions of the layer of semiconducting material will become source/drain structures of the FinFET device, forming a gate insulation layer around at least a portion of the fin structure and forming a gate electrode above the gate insulation layer.
US08815658B2 Hetero-structured inverted-T field effect transistor
The present invention provides a method of forming a transistor. The method includes forming a first layer of a first semiconductor material above an insulation layer. The first semiconductor material is selected to provide high mobility to a first carrier type. The method also includes forming a second layer of a second semiconductor material above the first layer of semiconductor material. The second semiconductor material is selected to provide high mobility to a second carrier type opposite the first carrier type. The method further includes forming a first masking layer adjacent the second layer and etching the second layer through the first masking layer to form at least one feature in the second layer. Each feature in the second layer forms an inverted-T shape with a portion of the second layer.
US08815655B2 Method for manufacturing semiconductor device
A method for manufacturing semiconductor device is disclosed. A substrate with a conductive layer is provided, and a dummy layer is formed on the conductive layer. The dummy layer and at least a portion of the conductive layer are patterned to form several trenches. A first dielectric layer is formed to fill into the trenches so as to form several first dielectric elements in the trenches. The dummy layer is removed to expose parts of the first dielectric elements. A second dielectric layer is formed on the exposed parts of the first dielectric elements, and the second dielectric layer is patterned so that a spacer is formed at a lateral side of each exposed first dielectric element. The conductive layer is patterned by the spacers, so that a patterned conductive portion is formed at each lateral side of each first dielectric element.
US08815650B2 Integrated circuit packaging system with formed under-fill and method of manufacture thereof
A method of manufacture of an integrated circuit packaging system includes: providing a substrate; mounting an integrated circuit above the substrate with an interconnect directly connecting between the substrate and the integrated circuit; and forming an under-fill between the integrated circuit and the substrate having a cast side.
US08815649B2 Multi-layer lead frame package and method of fabrication
The present invention features a method for fabricating a lead-frame package, having a first, second, third and fourth electrically conductive structures with a pair of semiconductor dies disposed therebetween defining a stacked structure. The first and second structures are spaced-apart from and in superimposition with the first structure. A semiconductor die is disposed between the first and second structures. The semiconductor die has contacts electrically connected to the first and second structures. A part of the third structure lies in a common plane with a portion of the second structure. The third structure is coupled to the semiconductor die.
US08815646B2 Semiconductor device adapted to improve heat dissipation
A semiconductor device is formed by molding using a resin with a semiconductor element and one or two heat dissipating plates contained therein, said one or two heat dissipating plates being disposed to face one surface or both the surfaces of the semiconductor element. An intermediate layer is formed by spraying a metal powder to the semiconductor element and to one of or both of the heat dissipating plates using a cold spray method, and the semiconductor element and the heat dissipating plate are bonded together using a solder with the intermediate layer therebetween.
US08815643B2 Method of fabricating semiconductor die with through-hole via on saw streets and through-hole via in active area of die
A semiconductor wafer contains a plurality of die with contact pads disposed on a first surface of each die. Metal vias are formed in trenches in the saw street guides and are surrounded by organic material. Traces connect the contact pads and metal vias. The metal vias can be half-circle vias or full-circle vias. Metal vias are also formed through the contact pads on the active area of the die. Redistribution layers (RDL) are formed on a second surface of the die opposite the first surface. Repassivation layers are formed between the RDL for electrical isolation. The die are stackable and can be placed in a semiconductor package with other die. The vias through the saw streets and vias through the active area of the die, as well as the RDL, provide electrical interconnect to the adjacent die.
US08815638B2 Method of manufacturing thick-film electrode
A method of manufacturing a thick-film electrode comprising the steps of: applying onto a substrate a conductive paste comprising a conductive powder, a glass frit, 3.5 to 12.5 weight percent of an organic polymer, and a solvent, wherein the weight percent is based on the total weight of the conductive powder, the glass frit, and the organic polymer; firing the applied conductive paste to form the thick-film electrode, wherein thickness of the thick-film electrode is 1 to 10 μm; and soldering a wire to the thick-film electrode.
US08815636B2 Oxides and glasses for use with aluminum back solar cell contacts
Solar cell contacts having good electrical performance are made by a process involving: (a) providing a silicon wafer substrate; (b) providing a paste comprising: (i) aluminum, (ii) glass frit, and (iii) a separate and distinct amount of at least one oxide, such that, together with the aluminum, the glass frit and oxide forms a paste having an exothermic reaction peak, at a temperature of at least 660° C. to less than 900° C., (c) applying the paste to the silicon wafer substrate to form a coated substrate, and (d) firing the coated substrate for a time and at a temperature sufficient to sinter the aluminum and fuse the glass frit and oxide.
US08815635B2 Manufacturing method of photoelectric conversion device
A photoelectric conversion device has a structure that includes a first amorphous silicon layer and a second amorphous silicon layer that are in contact with a single crystalline silicon substrate, and a first microcrystalline silicon layer with one conductivity type and a second microcrystalline silicon layer with a conductivity type that is opposite the one conductivity type that are in contact with the first and second amorphous silicon layers, respectively. The first and second microcrystalline silicon layers are formed using a plasma CVD apparatus that is suitable for high pressure film formation conditions.
US08815634B2 Dark currents and reducing defects in image sensors and photovoltaic junctions
Dark currents within a photosensitive device are reduced through improved implantation of a species during its fabrication. Dark currents can be caused by defects in the photo-diode device, caused during the annealing, implanting or other processing steps used during fabrication. By amorphizing the workpiece in the photo-diode region, the number of defects can be reduced thereby reducing this cause of dark current. Dark current is also caused by stress induced by an adjacent STI, where the stress caused by the liner and fill material exacerbate defects in the workpiece. By amorphizing the sidewalls and bottom surface of the trench, defects created during the etching process can be reduced. This reduction in defects also decreases dark current in the photosensitive device.
US08815631B2 Solar cell having doped semiconductor heterojunction contacts
A silicon solar cell has doped amorphous silicon contacts formed on a tunnel silicon oxide layer on a surface of a silicon substrate. High temperature processing is unnecessary in fabricating the solar cell.
US08815630B1 Back side illumination (BSI) sensors, manufacturing methods thereof, and semiconductor device manufacturing methods
Back side illumination (BSI) sensors, manufacturing methods thereof, and semiconductor device manufacturing methods are disclosed. In some embodiments, a method of manufacturing a semiconductor device includes providing a workpiece having a front side and a back side opposite the front side. An integrated circuit is formed on the workpiece, and a first insulating material is formed on the back side of the workpiece. A second insulating material is formed over the first insulating material. The second insulating material is patterned to form a grid on the back side of the workpiece.
US08815628B2 Complementary metal oxide semiconductor image sensor and method for fabricating the same
A complementary metal oxide semiconductor (CMOS) device and a method for fabricating the same are provided. The CMOS image sensor includes: a first conductive type substrate including a trench; a channel stop layer formed by using a first conductive type epitaxial layer over an inner surface of the trench; a device isolation layer formed on the channel stop layer to fill the trench; a second conductive type photodiode formed in a portion of the substrate in one side of the channel stop layer; and a transfer gate structure formed on the substrate adjacent to the photodiode to transfer photo-electrons generated from the photodiode.
US08815626B2 Low-profile MEMS thermal printhead die having backside electrical connections
A thermal printhead die is formed from an SOI structure as a MEMS device. The die has a printing surface, a buried oxide layer, and a mounting surface opposite the printing surface. A plurality of ink delivery sites are formed on the printing surface, each site having an ink-receiving and ink-dispensing structure. An ohmic heater is formed adjacent to each structure, and an under-bump metallization (UBM) pad is formed on the mounting surface and is electrically connected to the ohmic heater, so that ink received by the ink-delivery site and electrically heated by the ohmic heater may be delivered to a substrate by sublimation. A through-silicon-via (TSV) plug may be formed through the thickness of the die and electrically coupled through the buried oxide layer from the ohmic heater to the UBM pad. Layers of interconnect metal may connect the ohmic heater to the UBM pad and to the TSV plug.
US08815620B2 Flexible organic light-emitting display device and method of manufacturing the same
In a flexible organic light-emitting display device and a method of manufacturing the same, a photolysis layer and an electrostaticity prevention layer are sequentially formed on a carrier substrate, a first flexible substrate is formed on the electrostaticity prevention layer, a display unit is formed on the first flexible substrate, the display unit is covered with the second flexible substrate, and light is irradiated so as to decompose the photolysis layer and to remove the carrier substrate. The formed flexible organic light-emitting display device may have improved flexibility because a flexible substrate is used instead of a typical strong and thick glass substrate. In addition, occurrence of electrostaticity during the separation of the carrier substrate is suppressed by the electrostaticity prevention layer, and thus, damage of the display unit due to electrical impacts is also reduced.
US08815617B2 Passivation of VCSEL sidewalls
A semiconductor structure configured for use in a VCSEL or RCLED. The semiconductor structure includes an oxidizing layer constructed from materials that can be oxidized during a lithographic process so as to create an oxide aperture. The semiconductor structure further includes a number of layers near the oxidizing layer. A passivation material is disposed on the layers near the oxidizing layer. The passivation material is configured to inhibit oxidation of the layers.
US08815612B2 Ferroelectric memory device and fabrication process thereof, fabrication process of a semiconductor device
A ferroelectric memory device includes a field effect transistor formed on a semiconductor substrate, an interlayer insulation film formed on the semiconductor substrate so as to cover the field effect transistor, a conductive plug formed in the interlayer insulation film in contact with the first diffusion region, and a ferroelectric capacitor formed over the interlayer insulation in contact with the conductive plug, wherein the ferroelectric capacitor includes a ferroelectric film and upper and lower electrodes sandwiching the ferroelectric film respectively from above and below, the lower electrode being connected electrically to the conductive plug, a layer containing oxygen being interposed between the conductive plug and the lower electrode, a layer containing nitrogen being interposed between the layer containing oxygen and the lower electrode, a self-aligned layer being interposed between the layer containing nitrogen and the lower electrode.
US08815610B2 Magnetic nanoparticle detection across a membrane
Magnetic nanoparticles are detected across a thin membrane that separates the nanoparticles from a magnetic sensor. The technique can be used in a medical context, in which an analyte of interest (present in a test fluid, such as blood) is attached to the membrane. Other compounds are in turn bound to the analyte, with one of these compounds including a magnetic nanoparticle that is then detected by the sensor. In this way, the analyte is detected by detecting the magnetic nanoparticle. By counting the number of magnetic nanoparticles, the concentration of the analyte in the test fluid can be determined.
US08815606B2 Thin-layer chromatography and colorimetric analysis of multi-component explosive mixtures
A thin-layer chromatography method for detection and identification of common military and peroxide explosives in samples includes the steps of provide a reverse-phase thin-layer chromatography plate; prepare the plate by marking spots on which to deposit the samples by touching the plate with a marker; spot one micro liter of a first standard onto one of the spots, spot one micro liter of a second standard onto another of the spots, and spot samples onto other of spots producing a spotted plate; add eluent to a developing chamber; add the spotted plate to the developing chamber; remove the spotted plate from the developing chamber producing a developed plate; place the developed plate in an ultraviolet light box; add a visualization agent to a dip tank; dip the developed plate in the dip tank and remove the developed plate quickly; and detect explosives by viewing said developed plate.
US08815604B2 Microchannel chip and method for gas-liquid phase separation using same
A microchannel chip having a microchannel formed in a substrate and a gas-liquid phase separation microchannel whose upper part is covered with a porous film, the gas-liquid phase separation microchannel being connected to the downstream end of the microchannel and having a depth of 10 μm to 100 μm. Also, a gas-liquid phase separation method which is a method for separating a liquid-phase flow from a two-phase flow flowing through a microchannel by removing a gas phase, the two-phase flow composed of the gas phase and the liquid phase, which liquid phase flows in the periphery of the above-described microchannel and which gas phase flows interiorly of the liquid-phase flow.
US08815600B2 Homologous recombination-based DNA cloning methods and compositions
Methods and compositions for cloning a donor DNA molecule into an acceptor vector at a predetermined location are described. The methods are based on homologous recombination mediated by in vitro treatment of the donor DNA and the acceptor vector with an enzyme cocktail containing an exonuclease and a single-stranded DNA binding protein.
US08815598B2 Trophectodermal cell-specific gene transfer methods
The present inventors discovered that genes could be introduced specifically into trophectodermal cells with high efficiency, by infecting blastocysts with viral vectors carrying an arbitrary polynucleotide, or by using a nucleic acid transfection reagent in blastocysts, from which zona pellucida (extracellular matrix covering preimplantation early embryos to protect them from infection of viruses and the like) is removed. This method has no risk of infecting cells of the inner cell mass, which develops into a fetus in the future, with the introduced polynucleotide because the trophectoderm serves as a barrier. The present invention provides methods for introducing foreign genes into only placenta but not fetus, which enables rescue of genetically mutant animals from embryonic lethality due to placental abnormality and allows their birth. Furthermore, it is possible to analyze expression and effect of genes that regulate placental formation or placental function by using these methods.
US08815594B2 Hybrid tissue scaffold for tissue engineering
A hybrid tissue scaffold is provided which comprises a porous primary scaffold having a plurality of pores and a porous secondary scaffold having a plurality of pores, wherein the secondary scaffold resides in the pores of the primary scaffold to provide a hybrid scaffold. The pores of the porous primary scaffold may have a pore size in a range of 0.50 mm to 5.0 mm, and the pores of the porous secondary scaffold may have a pore size in a range of 50 μm to 600 μm. The primary scaffold may provide 5% to 30% of a volume of the hybrid scaffold.
US08815589B2 Methods of generating neural stem cells
The present disclosure provides methods of generating neural stem cells from differentiated somatic cells. The present disclosure also provides induced neural stem cells generated using a subject method, as well as differentiated cells generated from a subject induced neural stem cell. A subject neural stem cell, as well as differentiated cells derived from a subject neural stem cell, is useful in various applications, which are also provided in the present disclosure.
US08815588B2 Mesenchymal stem cell conditioned medium
We disclose a method of preparing a conditioned cell culture medium, the method comprising the steps of: (a) culturing a mesenchymal stem cell (MSC), a descendent thereof or a cell line derived therefrom in a cell culture medium; and (b) optionally isolating the cell culture medium; in which the mesenchymal stem cell (MSC) is obtained by propagating a cell obtained by dispersing a embryonic stem (ES) cell colony, or a descendent thereof, in the absence of co-culture in a serum free medium comprising FGF2.
US08815587B2 Postpartum cells derived from umbilical tissue and methods of making and using the same
Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
US08815585B2 Automated method and apparatus for embryonic stem cell culture
The invention concerns methods for automated culture of embryonic stem cells (ESCs) such as human ESCs. In some aspects, methods of the invention employ optimized culture media and limited proteolytic treatment of cells to separate cell clusters for expansion. Automated systems for passage and expansion of ESCs are also provided.
US08815583B2 Cell lines for expressing enzyme useful in the preparation of amidated products
Cell lines are provided for expressing peptidylglycine alpha-amidating monooxygenase (PAM), or one of its two catalytic domains. High levels of enzyme expression are achieved while utilizing a non-animal source, low protein tissue culture medium. A robust two-step downstream purification results in high enzyme purity. Resulting PAM, or its PHM catalytic domain, is used to catalyze the enzymatic conversion of X-Gly to X-alpha-hydroxy-Gly or X—NH2 (X being a peptide or any chemical compound having a carbonyl group to which a glycine group can be covalently attached). Methods of preparing preferred cell lines are also set forth.
US08815582B2 Mammalian cell expressing Volvox carteri light-activated ion channel protein (VChR1)
Methods, systems and devices are implemented in connection with light-responsive ion channel molecules. One such method is implemented using a light-activated ion channel molecule that responds to a light stimulus. The method includes engineering the light-activated ion channel molecule in a cell; and activating the ion channel molecule, in response to light stimulus that is provided to the ion channel molecule and that has properties that do not activate a ChR2 ion channel, to allow ions to pass through the light-activated ion channel molecule.
US08815581B2 Method for proliferating stem cells by activating c-MET/HGF signaling and notch signaling
The present invention relates to stem cells in which a gene that activates signaling is introduced and to a method for proliferating the stem cells. More specifically, the invention relates to a method of significantly increasing the ability of stem cells to proliferate, either by transfecting stem cells with the Notch intracellular domain (NICD) to activate the Notch signaling pathway, or by transfecting stem cells with the c-MET gene and treating the transfected stem cells with the HGF ligand protein to activate the c-MET/HGF signaling pathway. According to the present invention, as a result of activating the Notch signaling pathway or the c-MET/HGF signaling pathway, stem cells having an excellent ability to proliferate can be produced in large amounts. Particularly, since neural stem cells which have been difficult to culture in vitro can be proliferated in large amounts, thus the neural stem cells will be more useful for the preparation of cell therapeutic agents for treating cranial nerve diseases.
US08815575B2 Stepping optical reduction system
A device and a method for synthesizing a microarray are provided. The device includes a reduction optics assembly and a target assembly. The reduction optics assembly is configured to receive a light array of selectable regions of light and dark areas, to reduce a size of the light array in two-dimensions, and to project a pattern of the light array on a target surface. The target assembly includes a first stage and a second stage. The first stage is configured to move the target surface in at least two directions in plane with the projected pattern with a first precision. The second stage is mounted to the first stage and is configured to move the target surface in the at least two directions in plane with the projected pattern with a second precision that is smaller than the first precision.
US08815572B2 Nucleic acid extraction apparatus
The present invention relates to a nucleic acid extracting apparatus, and the nucleic acid extracting apparatus can include a pipe-shaped tube having an open outlet at one side thereof, and a hydrogel supporting member that is provided inside the tube and filters impurities excluding an extraction target material.
US08815557B2 Compositions and methods for refolding of denatured proteins
Compounds and methods for refolding of proteins in an aqueous solution. In particular, biocompatible multiblock copolymer surfactants such as poloxamers, meroxapols, poloxamines, or polyols are used to catalyze proper refolding without changing the protein composition, and restore the protein to its native conformation and native biological function. The methods can be practiced both in vivo and in vitro. The biocompatible multiblock copolymer surfactants can be used for renaturation of recombinantly expressed proteins, and for renaturation of proteins that are unfolded due to heat, irradiation, mechanical shearing, electrical shock, frostbite, chemical stress, and other abiotic or biotic stresses.
US08815556B2 Compositions and methods for tissue engineering, tissue regeneration and wound healing
In accordance with certain embodiments of the present disclosure, a kit is described. The kit includes primed living cells joined to and at least partially within a three-dimensional hydrogel structure and an isolated polypeptide having the carboxy-terminal amino acid sequence of an alpha Connexin, or a conservative variant thereof, wherein the polypeptide does not include the full length alpha Connexin protein.
US08815553B2 Engineering of yeast for cellulosic ethanol production
The disclosure provides designer cellulosomes for efficient hydrolysis of cellulosic material and more particularly for the generating of ethanol.
US08815544B2 Production of galactosylated glycoproteins in lower eukaryotes
The present invention provides a novel lower eukaryotic host cell producing human-like glycoproteins characterized as having a terminal β-galactose residue and essentially lacking fucose and sialic acid residues. The present invention also provides a method for catalyzing the transfer of a galactose residue from UDP-galactose onto an acceptor substrate in a recombinant lower eukaryotic host cell, which can be used as a therapeutic glycoprotein.
US08815538B2 Method of making cosmetic compositions containing a prebiotic
A method for indentifying test agents that exhibit prebiotic activity on human skin commensal microorganisms and cosmetic compositions that include such agents. The method includes providing a test culture of a test agent, a human skin commensal microorganism and a minimal carbon medium. The method provides a time efficient and cost effective way to predict in vivo prebiotic activity of a test agent on skin commensal microorganisms.
US08815537B2 Method for determining a complete blood count on a white blood cell differential count
Systems and methods analyzing body fluids such as blood and bone marrow are disclosed. The systems and methods may utilize an improved technique for applying a monolayer of cells to a slide to generate a substantially uniform distribution of cells on the slide. Additionally aspects of the invention also relate to systems and methods for utilizing multi color microscopy for improving the quality of images captured by a light receiving device.
US08815535B2 Disk diffusion assay for oritavancin
The present invention is directed to a disk diffusion assay for determining susceptibility of bacteria to a glycopeptide antibiotic. The assay includes improvements over conventional assays due to the inclusion of polysorbate 80 and Span 80 in the antibacterial solution used to impregnate paper disks used in the assay.
US08815534B2 Method for assessing the efficacy of a TR1 cell therapy in a subject
A method for assessing whether a patient subjected to an antigen-specific Tr1 cell therapy is responding to the treatment, includes: determining in vitro the antigen-specific proliferation of T cells contained in a cell sample from the patient; and comparing the antigen-specific proliferation to a standard reference, thereby determining whether the patient is responding or not to the treatment.
US08815532B2 Color-producing diagnostic systems, reagents and methods
Provided herein are novel reagents and their use in color-producing detection systems for performing diagnostic tests and analytical assays.
US08815531B2 Dry test strip and method for measuring creatinine
A dry test strip for measuring creatinine comprises: a support; a reagent layer that is disposed on the support; a reagent holding layer that is disposed on the reagent layer; and a connection layer that is composed of an adhesive which adhesively bonds the reagent layer to the reagent holding layer and is formed in spot form, wherein the reagent layer contains creatininase and 4-aminoantipyrine; the reagent holding layer contains creatinase, sarcosine oxidase, peroxidase, and N-ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethoxyaniline; and the connection layer delays arrival of a liquid sample spot-deposited on the reagent holding layer at the reagent layer.
US08815529B2 Sulfotransferase assay
Assays and methods for detecting and/or quantifying activity of a test sulfotransferase comprising by releasing a free phosphate from the PAP produced by the sulfotransferase reaction and detecting the free phosphate. The assay can includes gPAPP, a free phosphate detector and an optional control sulfotransferase. The method includes combining a test sulfotransferase with the substrate of the sulfotransferase, PAPS and gPAPP and detecting the free phosphate. The level of free phosphate directly correlates to the activity of the sulfotransferase. The assay and methods can be used to screen agents for their effect upon sulfotransferase activity.
US08815526B2 Methods and reagents for identifying/isolating T regulatory (Treg) cells and for treating individuals
An affinity ligand is reactive to the GARP protein may be capable of binding to an extracellular domain of GARP protein expressed on regulatory T (Treg) cells. The affinity ligand may be an antibody and may be used to identify Treg cells. A method comprises providing a blood sample from a subject and determining the amount of Treg cells in that sample. A composition containing Treg cells may be administered to an individual to suppress effector T cell activity in the individual. A composition containing an affinity ligand capable of binding to a GARP domain may be administered to an individual to suppress Treg cell activity and increase effector T cell activity in the individual. A kit for detecting Treg cells may include an affinity ligand reactive with mammalian GARP protein.
US08815525B2 Binding and functional assays that use the T1R3 receptor to screen for taste modulatory compounds
Newly identified mammalian taste-cell-specific G protein-coupled receptors, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in taste signaling, and the genes and cDNA encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for representing taste perception of a particular tastant in a mammal are also described, as are methods for generating novel molecules or combinations of molecules that elicit a predetermined taste perception in a mammal, and methods for simulating one or more tastes. Further, methods for stimulating or blocking taste perception in a mammal are also disclosed.
US08815523B2 Method for live-cell activity assay
Provided are technologies capable of direct measurement of activity of a bioactive substance in cell using nanowires, more particularly, a method for measuring intracellular activity of a bioactive substance using a nanowire support to which cells are immobilized and a nanowire support to which target substances for the subject bioactive substance are immobilized, and a chip for measuring intracellular activity of a bioactive substance including nanowires to which cells are immobilized and nanowires to which a target substance for the subject bioactive substance is immobilized.
US08815522B2 Decoy influenza therapies
The present invention provides umbrella-topology glycan decoys. The present invention provides systems and methods treating influenza infection utilizing inventive umbrella-topology glycan decoys. The present invention provides methods for identifying novel umbrella-topology glycan decoys.
US08815521B2 Apparatus and method for cell disruption
An apparatus for disrupting cells or viruses comprises a container having a chamber for holding the cells or viruses. The container includes at least one flexible wall defining the chamber. The apparatus also includes a transducer for impacting an external surface of the flexible wall to generate pressure waves in the chamber. The apparatus also includes a pressure source for increasing the pressure in the chamber. The pressurization of the chamber ensures effective coupling between the transducer and the flexible wall. The apparatus may also include beads in the chamber for rupturing the cells or viruses.
US08815519B2 Method for predicting cancer and other diseases
The invention concerns a marker for low-grade inflammation and metabolic syndrome (MS) and MS-related diseases and/or low-grade inflammation-related diseases such as cardiovasculardisease, ischemic heart disease and type 2 diabetes. More particularly it concerns the measurement of the concentration of soluble urokinase plasminogen activator receptor (suPAR) in human biological fluids (sputum, cystic fluid, ascites, serum, plasma, urine) as a tool of diagnosing and/or prognosticating low-grade inflammation and metabolic syndrome and the risk of development of the related diseases such as cancer, cardiovascular disease, ischemic heart disease and type 2 diabetes.
US08815514B2 Detection primers for nucleic acid extension or amplification reactions
Disclosed are methods and compositions related to real-time PCR and other nucleic acid extension or amplification reactions.
US08815513B2 Method for rapid detection and identification of bioagents in epidemiological and forensic investigations
The present invention provides methods for rapid forensic investigations by identification of bioagents associated with biowarfare and acts of terrorism or crime. The methods are also useful for epidemiological investigations by genotyping of bioagents.
US08815509B2 Fluorescence-based assay for the rapid detection and quantification of deoxyribonucleoside triphosphates
The inventors have developed a rapid and sensitive fluorescence-based assay to quantify dNTPs. This assay relies on the principle that incorporation of a limiting dNTP is required for primer-extension and polymerase-mediated 5-3′ exonuclease hydrolysis of a quenched fluorophore-labeled probe resulting in fluorescence. The concentration of limiting dNTPs is directly proportional to the fluorescence generated. This assay has important applications in research that investigates the influence of pathological conditions or pharmacological agents on dNTP biosynthesis and regulation.
US08815507B2 Method and materials for the cooperative hybridization of oligonucleotides
A two-stranded intermediary complex and cooperative hybridization method are provided. The complex has been designed so that target oligonucleotides of independent sequence can cooperatively and simultaneously hybridize to it. The cooperative hybridization mechanism is robust and modular, smoothly integrating with other dynamic DNA components to form cascaded reaction networks that can perform a variety of functions.
US08815506B2 Method for the in vitro diagnosis or prognosis of testicular cancer
A method for in vitro diagnosis or prognosis of testicular cancer in a biological sample from a patient suspected of suffering from testicular cancer, having a step of detecting the presence or absence of methylation of CpG dinucleotides in at least one genomic DNA target sequence of the sample, the target sequence being selected from at least one of the sequences identified in SEQ ID NOS: 1 to 7 or from at least one sequence which exhibits at least 99% identity with one of the sequences identified in SEQ ID NOS: 1 to 7 and the sequences complementary thereto; to the DNA sequences and to the use thereof as a testicular cancer marker.
US08815505B2 Use of regulatory sequences for specific, transient expression in neuronal determined cells
The present invention relates to the use of regulatory sequences for mediating specific, early transient expression in proliferative neuronal determined cells. Furthermore, the uses of recombinant nucleic acid molecules comprising said defined regulatory sequences for mediating specific, early transient expression in proliferative neuronal determined cells as well as for the generation of non-human transgenic organisms and/or host cells are disclosed. In addition, the invention provides for transgenic non-human animals and/or host cells comprising said regulatory sequences and/or recombinant nucleic acid molecules. The invention also describes methods for the preparation of such vectors, host cells and transgenic non-human animals as well as methods for the detection and/or isolation of neuronal determined cells. Additionally, methods for screening of compounds capable of regulating neuronal determined cell activity, neurogenesis, stimulating proliferation of neuronally committed precursor cells and/or neuronal differentiation are provided and the invention also relates to methods for the detection and analysis of neuronal differentiation, neuronal migration and/or neuronal determination processes. Finally, the invention relates to diagnostic and pharmaceutical compositions comprising the regulatory sequences, recombinant nucleic acid molecules, host-cells or isolated neuronal determined cells described herein.
US08815504B2 DNA amplification and sequencing using DNA molecules generated by random fragmentation
The present invention is directed to methods to prepare a DNA molecule or a plurality of DNA molecules by random fragmentation. In some embodiments, the present invention regards preparing a template for DNA sequencing by random fragmentation. In specific embodiments, the random fragmentation comprises chemical fragmentation, mechanical fragmentation, or enzymatic fragmentation. In further specific embodiments, a universal sequence is attached to the 3′ end of the DNA fragments, such as by ligation of an adaptor sequence or by homopolymeric tailing with terminal deoxynucleotidyltransferase. In other embodiments, a library is prepared with methods of the present invention.
US08815498B2 Method of forming tight-pitched pattern
The present invention provides a method of forming tight-pitched patterns. First, a target pattern is provided, wherein the target pattern comprises a plurality of first stripe patterns, and each of the first stripe patterns has a first width and a first length. Then, a photomask comprising a plurality of second stripe patterns corresponding to the first stripe patterns is provided, and each of the second stripe patterns has a second width and a second length. Then, a first exposure process with the photomask is provided in an exposure system, wherein the first exposure process uses a first light source that can resolve the second width of each of the second stripe patterns. Lastly, a second exposure process with the photo-mask is provided in the exposure system, wherein the second exposure process uses a second light source that cannot resolve the second width of each of the second stripe patterns.
US08815486B2 Carrier for two-component developer, two-component developer, image forming method, and image forming apparatus
A carrier for a two-component developer, includes: magnetic particles and a resin coating layer that is coated on the magnetic particles, the resin coating layer containing metal nitride particles having a volume average primary particle diameter of from about 300 to about 2,000 nm.
US08815481B2 Imaging member with fluorosulfonamide-containing overcoat layer
An imaging member includes a supporting substrate, an optional hole blocking layer, an optional adhesive layer, an imaging layer, and an overcoat layer, wherein the overcoat layer comprises a fluorosulfonamide. The overcoat layer can further include a charge transport compound and a melamine resin.
US08815479B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of manufacturing electrophotographic photosensitive member
An electrophotographic photosensitive member comprises a charge-transporting layer which is a surface layer of the electrophotographic photosensitive member; wherein the charge-transporting layer has a matrix-domain structure having: a matrix comprising a component [β] and a component [γ] (charge-transporting substances having specific structures), and a domain comprising a component [α](resin [α1], or resin [α1] and resin [α2]).
US08815473B2 Generalization of shot definitions for mask and wafer writing tools
Techniques for reducing the number of shots required by a radiation beam writing tool to write a pattern, such as fractured layout design, onto a substrate. One or more apertures are employed by a radiation beam writing tool to write a desired pattern onto a substrate using L-shaped images, T-shaped images, or some combination of both. By reducing the number of shots required to write a pattern onto a substrate, various implementations of the invention may reduce the write time and/or write complexity of the write process.
US08815468B2 Layered electrodes and membrane electrode assemblies employing the same
According to at least one aspect of the present invention, a layered catalyst having an active area is provided. In at least one embodiment, the layered electrode includes a first catalyst layer having a first noble metal concentration and a first ionomer concentration, and a second catalyst layer disposed next to the first catalyst layer, the second catalyst layer having a second noble metal concentration different from the first noble metal concentration and a second ionomer concentration different from the first ionomer concentration. In at least another embodiment, the metallic alloy includes a metallic alloy of platinum, nickel, and cobalt.
US08815467B2 Membrane electrode assembly and fuel cells with improved lifetime
The present invention relates to a membrane electrode assembly comprising at least two electrochemically active electrodes separated by at least one polymer electrolyte membrane, the aforementioned polymer electrolyte membrane having fibrous reinforcing elements which at least partly penetrate the polymer electrolyte membrane, wherein at least some of the fibrous reinforcing elements have functional groups which have a covalent chemical bond between the fibers and the polymer of the polymer electrolyte membrane.The membrane electrode assembly is suitable for applications in fuel cells, especially in high-temperature polymer electrolyte fuel cells.
US08815464B2 Fuel cell
A fuel cell includes a membrane electrode assembly and a metal separator. The metal separator is stacked with the membrane electrode assembly. A reactant gas passage is provided between the membrane electrode assembly and the metal separator to supply a reactant gas along an electrode surface. The metal separator includes a reactant gas communication hole to communicate with the reactant gas passage. The metal separator further includes a plurality of groove groups each having a plurality of grooves press-formed to allow the reactant gas communication hole to communicate with the reactant gas passage. The grooves adjacent to each other are spaced apart by a first distance. The groove groups adjacent to each other are spaced apart by a second distance larger than the first distance.
US08815463B2 Fuel cell system and its control method
Deterioration of an electrolyte and a sealing member is suppressed taking account of the durable temperature characteristics thereof, while enhancing the starting performance of a fuel cell. For this realization, in a system comprising a gas piping system for supplying a reactant gas to a fuel cell, and a gas supply controller for altering the supply state of the reactant gas in response to a power generation request, a gas supply quantity is altered in accordance with the temperature of the fuel cell. Preferably, the gas supply quantity is altered in accordance with the durable temperature characteristics of a passage member forming a gas passage of the reactant gas. Furthermore, the differential pressure of the gas supply state between the anode side and the cathode side of the fuel cell is preferably taken into account and the differential pressure between both poles is suppressed by altering the gas supply quantity on the cathode side as the case may be.
US08815459B2 Fuel cell stack with stoichiometry determination in individual cells
A fuel system including a fuel cell including a plurality of unit cells supplied with a prescribed gas to generate electricity, a stoichiometric ratio calculating apparatus calculating the stoichiometric ratio of the prescribed gas for each unit cell, and a gas flow increasing apparatus increasing the supply of the prescribed gas when the stoichiometric ratio falls below a prescribed value.
US08815458B2 Fuel cell system and method for controlling stoppage of fuel cell system
A fuel cell system for a vehicle includes a fuel cell, a fuel supply device, an oxidizer supply device, an anode potential measuring device, and a discharge controller. The anode potential measuring device is configured to measure an anode potential of an anode. The discharge controller is configured to control discharge of electric current from the fuel cell as part of a process of stopping the fuel cell during idling of the vehicle. When receiving idle stop permission for the fuel cell, the discharge controller determines whether the fuel cell is permitted to discharge. When the anode potential is equal to or lower than a predetermined threshold value, the discharge controller permits the fuel cell to discharge. When the anode potential is higher than the predetermined threshold value, the discharge controller does not permit the fuel cell to discharge.
US08815456B2 Fuel cell system
A fuel cell system comprising a generation chamber, a plurality of fuel cells arranged in the generation chamber, fuel gas feeding means for feeding a fuel gas to the fuel cells, oxygen-containing gas feeding means for feeding an oxygen-containing gas to the fuel cells, power converter means for converting the DC output of the fuel cells into an alternating current, power control means for controlling the electric power output to the power converter means from the fuel cells, and generation control means for controlling the flow rate of the fuel gas fed to the fuel cells and the flow rate of the oxygen-containing gas fed to the fuel cells. A fuel gas buffer amount specific to the fuel cells is not smaller than a fuel gas amount that is needed within a maximum period of increase-needing time that is necessary until the flow rate of the fuel gas increases to a required amount when the amount of increase in the flow rate of the fuel gas is set to be a maximum. The generation control means sets the flow rate of the fuel gas and the flow rate of the oxygen-containing gas based on an electric current of the fuel cells.
US08815454B2 Lithium secondary battery
A lithium secondary battery includes a positive electrode, a negative electrode, a separator separating the positive electrode and the negative electrode, and an electrolyte. The negative electrode active material of the negative electrode includes a material that is capable of reversibly intercalating and deintercalating lithium ions and a metallic material capable of alloying with lithium. The electrolyte includes a chemical compound containing a nitrile (—CN) radical.
US08815449B2 Positive electrode and non-aqueous electrolyte secondary battery
A material (hereinafter referred to as “positive electrode material”) including sodium manganate powder as a positive electrode active material, carbon black powder as a conductive agent, and polytetrafluoroethylene as a binder is prepared. The positive electrode material is mixed in an N-methylpyrrolidone solution to produce slurry as a positive electrode mixture. A working electrode is produced by applying the slurry on a positive electrode collector. A negative electrode containing tin or germanium is produced. The non-aqueous electrolyte is produced by adding sodium hexafluorophosphate as an electrolyte salt in a non-aqueous solvent produced by mixing ethylenecarbonate and diethyl carbonate.
US08815447B2 Proton-conductive inorganic material for fuel cell and fuel cell anode employing the same
The present invention aims to provide a fuel cell anode, a membrane electrode assembly and a fuel cell, so as to obtain high electric power. The fuel cell anode has an electrode catalyst layer, and the electrode catalyst layer comprises a supported catalyst comprises electrically conductive carriers and fine catalytic particles supported thereon, a proton-conductive inorganic oxide supporting SiO2 on its surface, and a proton-conductive organic polymer binder. The SiO2 supported on the inorganic oxide prevents the oxide particles from growing, to ensure the high electric power. It is necessary to control the mixing ratios among the supported catalyst, the proton-conductive oxide and the proton-conductive binder in particular ranges.
US08815445B2 Cathode active material for lithium secondary battery
Provided is a cathode active material for a lithium secondary battery, which can achieve both of excellent rate characteristic and practically sufficient durability (cycle characteristic) in the lithium secondary battery. The cathode active material for a lithium secondary battery includes therein pores. A particle or film of the cathode active material for a lithium secondary battery has formed therein a large number of pores. The inner wall of each of such pores is coated with a conductive film.
US08815444B1 Composite current collector for an aqueous electrochemical cell comprising a non-metallic substrate
Composite current collectors containing coatings of metals, alloys or compounds, selected from the group of Zn, Cd, Hg, Ga, In, Tl, Sn, Pb, As, Sb, Bi and Se on non-metallic, non-conductive or poorly-conductive substrates are disclosed. The composite current collectors can be used in electrochemical cells particularly sealed cells requiring a long storage life. Selected metals, metal alloys or metal compounds are applied to polymer or ceramic substrates by vacuum deposition techniques, extrusion, conductive paints (dispersed as particles in a suitable paint), electroless deposition, cementation; or after suitable metallization by galvanic means (electrodeposition or electrophoresis). Metal compound coatings are reduced to their respective metals by chemical or galvanic means. The current collectors described are particular suitable for use in sealed primary or rechargeable galvanic cells containing mercury-fee and lead-free alkaline zinc electrodes.
US08815442B2 Textile electrode and accumulator containing such an electrode
The invention relates to an electrode comprising (a) an electron collector containing one or more transition metals from the groups 4 to 12 of the Periodic Classification of the Elements, and (b) a material that is electrochemically active, present on the surface of the electron collector in the form of a nano-structured conversion layer containing nano-particles or agglomerates of said nano-particles, wherein the nano-particles have a mean diameter of between 1 and 1000 nm, preferably between 10 and 300 nm, wherein said electrochemically active material contains at least one compound of the transition metal or transition metals present in the electron collector, characterized by the fact that the electrode is a textile formed by metallic wires or fibers. The invention also relates to a half-accumulator and an accumulator containing such a textile electrode.
US08815440B2 Battery cover member
A battery cover member (10) of the present invention includes a metallic electrode terminal (40), a metallic cover member (30) having through holes (32), and an insulating resin member (50), in which the electrode terminals inserted into the through hole and the cover member are integrally bonded together by the insulating member, wherein at least a sealing area (70) of the electrode terminal that adheres to the insulating member is formed as a columnar shape or an elliptically columnar shape.
US08815437B2 Rechargeable battery
A rechargeable battery is disclosed. In one embodiment, the battery includes: i) a first current collecting plate, ii) a plurality of electrode assemblies electrically connected in parallel with each other via the first current collecting plate, wherein each of the electrode assemblies comprises two opposing ends and an outer side formed between the two ends, and wherein the first current collecting plate is electrically connected to one of the two ends of the electrode assemblies and iii) a can configured to accommodate the first current collecting plate and the plurality of electrode assemblies, wherein the can comprises at least one non-linear portion, and wherein an inner surface of the non-linear portion faces the outer side of at least one electrode assembly.
US08815430B2 Sealed battery and battery stack comprising a plurality of sealed batteries
A sealed battery includes a lid closing a container of a sealed battery, an upper current collecting plate, a lead connecting an upper surface to an inner surface of the lid. A welding point of the lead is outside a position corresponding to a periphery of the cap. The lead includes a cylindrical lateral wall part extending vertically, an annular frame portion extending substantially horizontally from a first end of the lateral wall part, and a plurality of supplementary leads that extends substantially horizontally from a second end part of the lateral wall part. The frame portion extends from the first end part in substantially a first direction along a radial direction of the cylindrical lateral wall part, whereas the plurality of supplementary leads extends from the second end part in substantially a second direction opposite to the first direction along the radial direction.
US08815427B2 Spirally wound non-aqueous electrolyte secondary battery having insulating members
A spirally-wound non-aqueous electrolyte secondary battery including a staked electrode assembly is disclosed. The stacked electrode assembly has first and second current collectors facing region disposed at a winding start end and at a winding terminal end, respectively. A positive electrode current collector exposed portion and a negative electrode current collector exposed portion face each other through the separator in each of the first and second current collector facing regions. At least one of the positive or negative electrode current collector exposed portion has a first insulating member formed thereon in the first current collector facing region at the winding start end. At least one of the positive or negative electrode current collector exposed portion has a second insulating member formed thereon in the second current collector facing region at the winding terminal end.
US08815422B2 Battery pack
A battery pack and a method for fabricating the same are provided. The battery pack includes a plurality of battery cells connected in series or in parallel to each other, a protective circuit module (PCM) controlling charging and discharging of the plurality of battery cells, and a coverlay electrically connecting the plurality of battery cells to the PCM, wherein the coverlay includes a plurality of wires, each of the plurality of wires includes battery connecting pads provided at its one end, the battery connecting pads connected to the battery cells, and module connecting pads provided at it's the other end, the module connecting pads connected to the PCM, and a solder layer is formed on the battery connecting pads.
US08815417B2 Heterocyclic compound and organic light-emitting device including the same
A heterocyclic compound represented by Formula 1 below and an organic light-emitting device including the heterocyclic compound: wherein R1 to R12 are defined as in the specification.
US08815416B2 Organic electroluminescent device using a bipyrimidine compound
Disclosed is an organic electroluminescent device (organic EL device) which is improved in luminous efficiency, fully secured of driving stability, and of simple constitution. Also disclosed is a compound useful for the fabrication of said organic electroluminescent device. This compound for organic electroluminescent device is a bipyrimidyl compound which has a basic skeleton of 2,2′-bipyrimidyl and is substituted by an aromatic hydrocarbon group, an aromatic heterocyclic group, or a substituted amino group. The aforementioned organic electroluminescent device has a light-emitting layer between an anode and a cathode which are piled one upon another on a substrate and the light-emitting layer contains a phosphorescent dopant and the aforementioned bipyrimidyl compound as a host material.
US08815415B2 Blue emitter with high efficiency based on imidazo[1,2-f] phenanthridine iridium complexes
Imidazo[1,2-f]phenanthridine compounds are provided. The compounds have a twisted aryl moiety further substituted by alkyl having four or more atoms. The compounds may be used in organic light emitting devices, particularly as emissive dopants, providing devices with improved efficiency, stability, and manufacturing. In particular, the compounds provided herein may be used in blue devices having high efficiency.
US08815414B2 Polymer compound and polymer light emitting device using the same
A polymer compound having a repeating unit of the following formula (1): (wherein, R1 represents a substituent, Q1 and Q2 represent a group containing a benzocyclobutane structure, a represents an integer of 0 to 3. When there exist a plurality of R1s, these may be the same or different).
US08815413B2 Oxazole triplet emitters for OLED applications
The present invention relates to compounds which can be used in particular as ligands, to complexes of formula (I) and (II) and also to light-emitting devices and in particular to organic light-emitting devices (OLEDs). In particular, the invention relates to the use of luminescent oxazole-chelate metal complexes as emitters in such devices.
US08815410B2 Anthracene derivative, light emitting element using the same, and light emitting device using the same
It is an object of the present invention to provide a light emitting element, which is resistant to repetition of an oxidation reaction. It is another object of the invention to provide a light emitting element, which is resistant to repetition of a reduction reaction. An anthracene derivative is represented by a general formula (1). In the general formula (1), R1 represents hydrogen or an alkyl group having 1 to 4 carbon atoms, R2 represents any one of hydrogen, an alkyl group having 1 to 4 carbon atoms and an aryl group having 6 to 12 carbon atoms, R3 represents any one of hydrogen, an alkyl group having 1 to 4 carbon atoms, and an aryl group having 6 to 12 carbon atoms, Ph1 represents a phenyl group, and X1 represents an arylene group having 6 to 15 carbon atoms.
US08815409B2 Organic electroluminescent device
An organic electroluminescent device including at least one organic layer between a pair of electrodes, wherein the at least one organic layer includes a luminescent layer, at least one layer of the at least one organic layer includes at least one metal complex containing a tri- or higher-dentate ligand, and a compound represented by formula (I) is contained in an organic layer containing the metal complex and/or in other organic layer(s). In formula (I), R11 to R14 each independently represent a hydrogen atom or a substituent group, and at least one of R11 to R14 represents an aryl or heteroaryl group.
US08815408B1 Metal syntactic foam
A syntactic foam comprising hollow metallic shells and a solid metal foam matrix. The metal foam composites show high strength, particularly in comparison to previous metal foams, while maintaining a favorable strength to density ratio. The composite metal foams can be prepared by various techniques, such as powder metallurgy and casting or aspiration casting.
US08815407B2 Sliding bearing having improved lubrication characteristics
The present disclosure relates to a sliding bearing which is usefully applicable to equipment to which high surface pressure is applied, by processing an inner surface of a sliding bearing manufactured in the form of a sintered body to be optimized to lubrication characteristics.
US08815406B2 Display panel equipped with front plate, display device, and resin composition
The present invention provides a display panel equipped with a front plate and a display device, in each of which streak unevenness is sufficiently resolved in the periphery of a display area. The display panel equipped with a front plate of the present invention comprises: a display panel; a front plate; and a cured resin composition layer disposed between the display panel and the front plate, wherein the cured resin composition layer has a loss tangent of 2 or less at 0 to 70° C.
US08815405B2 Exterior deep base paint formulation
The present invention provides increased stain resistance, tannin blocking, adhesion, and various other properties. A composition in accordance with the principles of the present invention comprises at least three binders, nanoparticle pigment, and pigmentary titanium dioxide. In one embodiment, the present invention relates to a coating on a substrate wherein the coating has three binders, nanoparticle metal oxide pigment, and pigmentary titanium dioxide. Various additives may be included to formulate paint as known in the art.
US08815404B2 Protective film and encapsulation material comprising the same
Disclosed herein is a protective film. The protective film is produced by alternate coating of a polysilazane-based polymer and a flexible polysiloxane-based polymer. The polysilazane-based polymer is cured at low temperature to form silica, thereby achieving high hardness and high light transmittance. The protective film has improved interfacial adhesion between the respective coating films, which prevents permeation of moisture and oxygen. In addition, the protective film can be easily produced by low-temperature wet processes. Also disclosed herein is an encapsulation material comprising the protective film.
US08815401B2 Prepreg and laminate
A prepreg for a printed wiring board, comprising a cyanate ester resin having a specific structure, a non-halogen epoxy resin, a silicone rubber powder as a rubber elasticity powder, an inorganic filler and a base material, which prepreg retains heat resistance owing to a stiff resin skeleton structure, has high-degree flame retardancy without the use of a halogen compound or a phosphorus compound as a flame retardant, and has a small thermal expansion coefficient in plane direction without using a large amount of inorganic filler, and a laminate comprising the above prepreg.
US08815397B2 Carbon nanotube film
A carbon nanotube film includes a plurality of carbon nanotube strings and one or more carbon nanotubes. The plurality of carbon nanotube strings are separately arranged and located side by side. Distances between adjacent carbon nanotube strings are changed when a force is applied. One or more carbon nanotubes are located between adjacent carbon nanotube strings.
US08815388B2 Inorganic-organic hybrid material, optical material using the same, and inorganic-organic composite composition
The invention relates to an inorganic-organic hybrid material which comprises an inorganic component and an organic component, has a content of the inorganic component of 20-80% by mass, and has a refractive index of 1.60 or higher, wherein, when preparing a strip specimen having a thickness of 1,000 μm, a width of 5 mm and a length of 70 mm by using the inorganic-organic hybrid material and winding the specimen by 180° on a cylindrical metal rod having a diameter of 10 mm at 25° C., the specimen does not crack.
US08815385B2 Controlling peel strength of micron-scale structures
A fabricated microstructure includes a base and one or more nano-structures disposed on one or more portions of the base to adhere to a contact surface. The one or more portions of the base with the one or more nano-structures are located on the base such that, when the one or more nano-structures adhere to the contact surface and an external force is applied to peel the base from the contact surface, the one or more nano-structures in the one or more portions of the base facilitate or resist peeling of the nano-structures from the contact surface.
US08815382B2 Method and use of organic and mineral admixtures for EMI and radioactive isotope shielding of building materials such as glass fiber wall coverings, gypsum wallboard and electrically conductive or resistive, high performance, high strength concrete
A method is disclosed for the use of an organic admixture composed of a polysaccharide such as hydroxypropylcellulose and a monosaccharide such as ethoxylated methylglucoside and de-ionized water and minerals such as zeolites for electromagnetic; radio and microwave frequency and radioisotope shielding of building materials such as wall liners, gypsum wallboard and high performance, high strength concrete.
US08815381B2 Formation of boron carbide-boron nitride carbon compositions
A composition having nanoparticles of a boron carbide and a carbonaceous matrix. The composition is not in the form of a powder. A composition comprising boron and an organic component. The organic component is an organic compound having a char yield of at least 60% by weight or a thermoset made from the organic compound. A method of combining boron and an organic compound having a char yield of at least 60% by weight, and heating to form boron carbide or boron nitride nanoparticles.
US08815376B2 Surface treatment agent for hydraulic transfer, and hydraulic transfer method and hydraulic transfer products using same
A surface treatment agent for hydraulic transfer to perform hydraulic transfer decoration with high adhesion onto an olefin-type substrate with poor adhesion. They are provided by a surface treatment agent for hydraulic transfer to a polyolefin-type substrate to be used in a hydraulic transfer method for forming a decorative layer, by coating an activator to a dried print pattern on a water-soluble film to recover adhesion of said print pattern, and then by hydraulic transferring said print pattern onto the surface of a surface treatment layer of the polyolefin-type substrate treated with the surface treatment agent, characterized in that said surface treatment agent for hydraulic transfer is consisted of a resin composition including a modified polyolefin (a), a polyfunctional isocyanate (b) and a solvent (c), and a blending ratio of (b)/(a) is 0.005 to 0.5, in weight ratio.
US08815373B2 Bendable polycarbonate resin laminate, optically transparent electromagnetic wave shield laminate, and manufacturing method thereof
The present invention provides a method for manufacturing a laminate, comprising the steps of laminating two or more layers of polycarbonate resin film and/or sheet using a (meth)acrylate-based adhesive composition containing a (A) (meth)acrylate monomer, a (B) meth(acrylate) olygomer, an (C) acrylamide derivative, and a (D) silane compound and/or an (E) organophosphorus compound to form a laminate having a thickness of 0.1 mm to 30 mm; heating the laminate at 130° C. to 185° C. so that a temperature difference between a top surface and a bottom surface of the laminate is within 20° C.; and bending the post-heating laminate into a curved shape having a radius of curvature of 10 mm or greater.
US08815372B2 Gel cushion
A gel cushion, such as may be incorporated in a knee pad or other body-worn pad, that avoids undue accumulation of heat within the cushion, and that provides a stable and comfortable resting surface for at least a portion of a user's body. The cushion may further provide decreasing incremental compression in response to incrementally increasing loads, whereby users of different weights may be comfortably supported thereon.
US08815371B2 Structure and method for forming detailed channels for thin walled components using thermal spraying
A coated substrate with a subsurface cooling channel having no corner disposed proximate a seam between the substrate and the coating. A method for forming such a structure, including forming a groove in a surface of a substrate, forming a preform having a cooperating portion and a protruding portion, inserting the cooperating portion of the preform into the groove, leaving the protruding portion of the preform protruding beyond the surface of the substrate, applying a layer of a coating material to the surface of the substrate and the protruding portion of the perform, and removing the preform, thereby creating a cooling channel.
US08815370B2 Adhesiveless decorative floor tile
A decorative floor tile including at least one decorative layer and a backing layer having an array of resilient annular projections. Each annular projection includes a concave top surface, an outside wall surface, and an inside wall surface. The inside wall surface defines a central, blind passageway area. When the decorative floor tile is installed over an underlying surface, and pressure is applied to the decorative floor tile, a vacuum is created within the blind passageway and the underlying surface. The vacuum increases the amount of frictional drag between the surface covering and the underlying surface, and thus allows the surface covering to remain in place without the need for an adhesive.
US08815363B2 Multilayer protective liner
Disclosed is a multilayer structure useful for preparing highly abrasion-resistant protective liners, including tubular articles such as multilayer tubes or pipes.
US08815362B2 Method for making a reinforced balloon with composite materials
The method for making a reinforced balloon for a balloon catheter involves blending a polymer with a nano composite to form a composite matrix, extruding a parison from the composite matrix, blow molding the parison into a balloon and orienting the nano composite generally axially with respect to the balloon. The balloon formed has a high strength for resisting bursting. The nano composite may be carbon nanotubes, nano-ceramic fibers or a nano clay.
US08815361B2 Silicone urisheath with integrated adhesive
By using an oxidative process, it is possible to apply an adhesive material to silicone. The process is controlled, allowing selective oxidative treatment to a silicone structure, thus enabling treatment to the inside of a tubular structure.
US08815347B2 Antioxidant agent and process for producing metallic material
There is provided an antioxidant agent excellent in anti-dripping property and anti-peeling property. The antioxidant agent in accordance with the present invention contains a plurality of glass frits having different softening points, potter's clay, and bentonite and/or sepiolite. On account of the potter's clay, the antioxidant agent applied to the surface of a metallic starting material is less liable to drip down. Further, on account of the bentonite and/or sepiolite, the antioxidant agent is less liable to peel off the surface of the metallic starting material.
US08815343B2 Highly conductive and stable transparent conducting polymer films
The invention relates to a process for the synthesis of conducting polymer films by vapor phase polymerization. The invention relates particularly to the synthesis of polymerized thiophene films, for example poly(3,4-ethylenedioxythiophene) (PEDOT) films.
US08815342B2 Process for forming a protective coating on the surface of a metal part
The present invention relates to a process for forming on the surface of a metal part a protective coating containing aluminium and zirconium, in which process said part and a cement made of an aluminium alloy are brought into contact with a gas at a treatment temperature in a treatment vessel, the gas comprising a carrier gas and an activator, the activator reacting with the cement to form a gaseous aluminium halide that decomposes on the surface of the part, depositing metallic aluminium thereon, the activator containing a zirconium salt such as ZΓO (¾ obtained from granules of a zirconium salt), disassociation reactions of said zirconium salt taking place within a disassociation temperature range with formation of a Zr metal coating on the surface of the part, the assembly comprising the part, the cement and the zirconium salt granules is progressively heated in the chamber from room temperature up to the treatment temperature, the process being characterized in that the treatment chamber is maintained at an overpressure with no carrier gas flow throughout the temperature range corresponding to the disassociation reactions of the zirconium salt.
US08815341B2 Carbon fiber substrates having carbon nanotubes grown thereon and processes for production thereof
Processes for growing carbon nanotubes on carbon fiber substrates are described herein. The processes can include depositing a catalyst precursor on a carbon fiber substrate, optionally depositing a non-catalytic material on the carbon fiber substrate, and after depositing the catalyst precursor and the optional non-catalytic material, exposing the carbon fiber substrate to carbon nanotube growth conditions so as to grow carbon nanotubes thereon. The carbon nanotube growth conditions can convert the catalyst precursor into a catalyst that is operable for growing carbon nanotubes. The carbon fiber substrate can remain stationary or be transported while the carbon nanotubes are being grown. Optionally, the carbon fiber substrates can include a barrier coating and/or be free of a sizing agent. Carbon fiber substrates having carbon nanotubes grown thereon are also described.
US08815335B2 Method of coating a substrate with nanoparticles including a metal oxide
One exemplary embodiment may include a method comprising: depositing a solution comprising an organometallic compound on a substrate, drying the solution to provide a film of the organometallic compound and at least partially oxidizing an organic component of the organometallic compound to provide nanoparticles including metal oxides on the substrate which would have multiuse industrial applications.
US08815333B2 Manufacturing method of metal structure in multi-layer substrate
Disclosed is a manufacturing method of metal structure in multi-layer substrate. The manufacturing method includes following steps: coating at least one photoresist layer on a surface of a dielectric layer; exposing the photoresist dielectric layer to define a predetermined position of the metal structure; removing the photoresist layer at the predetermined position to undercut an edge of the photoresist layer adjacent to the predetermined position by a horizontal distance of at least 0.1 μm between a top and a bottom of the edge; forming the metal structure at the predetermined position; and forming at least one top-cover metal layer to cover a top surface and two side surfaces of the metal structure. The present invention can form a cover metal layer covering the top surface and the two side surfaces by one single photomask.
US08815331B2 Film-forming apparatus, method of cleaning the same, and method of manufacturing a light-emitting device
A cleaning method of removing a vapor-deposition material adhering to equipments without exposure to the atmosphere is provided. A vapor-deposition material adhering to equipments (components of a film-forming apparatus) such as a substrate holder, a vapor-deposition mask, a mask holder, or an adhesion preventing shield provided in a film-forming chamber are subjected to heat treatment. Because of this, the adhering vapor-deposition material is re-sublimated, and removed by exhaust through a vacuum pump. By including such a cleaning method in the steps of manufacturing an electro-optical device, the manufacturing steps are shortened, and an electro-optical device with high reliability can be realized.
US08815326B2 Temperature telemetry in processing of material
In the process of coating pharmaceutical tablets in a moving bed, the temperature of the tablets is measured by incorporating a temperature transducer in the form of tablet into the bed of tablets, and transmitting temperature data to an external receiver by wireless telemetry.
US08815325B2 Medicinal inhalation device
A medical inhalation device or a component thereof having a diamond-like glass coating comprising hydrogen and on a hydrogen free basis about 20 to about 40 atomic percent of silicon, greater than 39 atomic percent of carbon, and less than 33 down to and including zero atomic percent of oxygen.
US08815321B2 Geranylamine derivatives as flavouring agents
Compounds of the formula (I) A is OH or a carbonyl group, n is 0 or 1, R is an alkyl radical having from 1 to 4 carbon atoms, in particular methyl, ethyl, n-propyl, iso-propyl, n-butyl or t-butyl; or a residue of a hydroxy carboxylic acid, in particular the residue —CH(OH)COOH, —CH(OH)CH2COOH, —CH2CH(OH)COOH or —CH(OH)CH(OH)COOH; and R′ is independently selected from H or OH.
US08815318B2 Packages for dispensing liquid and dry food
Describe are food packages having features such as multiple containers in a single package and multiple pieces for a package; the packages can contain multiple food products including (for example) cereal and milk, for consumption together in a convenient manner.
US08815316B2 Enzyme product for ruminants
A method is described for improving the digestibility of a forage diet for ruminant animals. A forage, including alfalfa, Chinese wildrye, corn silage, straw silage, corn stover, ryegrass or TMR, is treated with an enzyme product having cellulase, xylanase, beta-glucanase, pectinase, mannanase and alpha-galactosidase activities.
US08815315B2 Use of a multi-protease system to improve the protein digestibility of animal feeds containing vegetable meals
Disclosed is a method for improving the digestibility and amino acid profile of proteinaceous animal feed products by the use of a combination of acidic, alkaline and/or neutral proteases. The selection and amounts of the proteases is based on the particular animal feed product and on the conditions of the gastrointestinal tract of the animal to be fed the treated animal feed. Use of the treated animal feed will reduce the amount of amino acid supplementation required, reduce the amount of nitrogen in animal feces, and improve the economical performance of the animal.
US08815313B2 Compositions of rose hips enriched with seeds of rose hips and their use as anti-inflammatory natural medicine for alleviating/reducing symptoms associated with inflammation and joint diseases such as arthritis, rheumatoid arthritis and/or osteo-arthritis
A composition containing rose hip flesh or rose hips including the naturally occurring amount of seeds, or a concentrate is enriched with rose hip seeds for reducing and/or alleviating symptoms of inflammatory diseases. A method of preparing the rose hip seeds involves separating the rose hip seeds from the flesh prior to or after drying. Drying is preferably performed below 50° C. with the rose hip seeds then ground into a powder and mixed with a rose hip composition, a concentrate or an extract containing rose hip shells or Rose hips including their naturally occurring amount of seeds providing a product enriched with Rose hips seeds preferably containing at least 50% up to 85%, (by weight) of rose hip seeds. The composition is useful in the prophylaxis, treatment or alleviation of symptoms related to inflammatory diseases, in particular joint diseases, such as arthritis rheumatoid arthritis and/or osteo arthritis.
US08815311B2 Methods for improving thyroid function in a subject
Embodiments of the invention generally relate to methods for improving thyroid function in healthy human beings.
US08815301B2 Stable iron oligosaccharide compound
The invention relates to an iron oligosaccharide compound with improved stability comprising a hydrogenated oligosaccharide in stable association with ferric oxyhydroxide, the content of dimer saccharide in said hydrogenated oligosaccharide being 2.9% by weight or less, based on the total weight of the hydrogenated oligosaccharide. In further aspects is provided a process for preparing said compound as well as the use of said compound for preparation of a composition for treatment of iron deficiency anaemia.
US08815297B2 Modulation of beta 2 adrenergic receptors by inhibitors of EGLN3 or pVHL
This present invention relates to methods, compositions, and kits useful for treating a patient having or at risk for developing a disorder associated with decreased expression of β2 adrenergic receptors or need for increased 132 adrenergic receptor activity.
US08815294B2 Pharmaceutical compositions of dextran polymer derivatives and a carrier material
Pharmaceutical compositions are provided comprising (a) nanoparticles of an active agent and a dextran polymer derivative, and (b) a carrier material.
US08815293B2 Organic compounds
A depot formulation comprising iloperidone and a biodegradable, biocompatible polymer. Preferably, the polymer is a star polymer.
US08815289B2 Tamper resistant dosage forms
The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.
US08815281B2 Transdermal drug delivery device including an occlusive backing
A transdermal drug delivery system for the topical application of one or more active agents contained in one or more polymeric and/or adhesive carrier layers, proximate to a non-drug containing polymeric backing layer which can control the delivery rate and profile of the transdermal drug delivery system by adjusting the moisture vapor transmission rate of the polymeric backing layer.
US08815279B2 Baby feeding formula and system
A method is provided for reducing the extent of or occurrence of long-term adverse health effects in human infants, comprising feeding to said infants when newborn a nutrient-containing-formula providing not more than 1 gram of protein per 100 ml of formula and/or not more than 50 kcal per 100 ml of formula. Also disclosed are methods of administering the infant formulas to reduce the occurrence or extent of insulin resistance in an individual later in life, to reduce the occurrence or extent of obesity or atherosclerosis in an individual later in life, or combinations thereof, by feeding newborn infants the newborn infant formula described herein.
US08815277B2 In situ forming hydrogel and biomedical use thereof
Disclosed are in situ-forming injectable hydrogel and medical uses thereof. In the in situ-forming injectable hydrogel two or more homogeneous or heterogeneous polymers are bonded to each other by a dehydrogenation reaction between phenol or aniline moieties on adjacent polymers, wherein a polymer backbone is grafted with a phenol or aniline moiety using a linker. In contrast to conventional hydrogel, the in situ-forming injectable hydrogel is superior in terms of in vivo stability and mechanical strength thanks to the introduction of a water-soluble polymer as a linker which leads to an improvement in the reactivity of phenol or aniline moieties. Having the advantage of superior bio stability and mechanical strength, the hydrogel finds a variety of applications in the biomedical field.
US08815275B2 Coatings for medical devices comprising a therapeutic agent and a metallic material
The invention relates generally to an implantable medical device for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. In particular, the invention pertains to an implantable medical device, such as an intravascular stent, having a coating comprising a first coating composition comprising a therapeutic agent and, optionally, a polymer; and a second coating composition comprising a metallic material.
US08815271B2 Pesticidal compositions and processes related thereto
This document discloses molecules having the following formula (“Formula One”): and processes related thereto.
US08815269B2 Insecticidal formulations with improved long-term effect on surfaces
The present invention relates to compositions for the control of pests, in particular insecticidal suspension concentrates and spray solutions made from them, to processes for their preparation, and to the use of such formulations for the sustained control of animal pests (arthropods) on a variety of surfaces. The present invention furthermore relates to the use of certain polymer dispersions in pesticides, in particular to their use for extending the long-term activity of these compositions when they are applied to surfaces. The present invention furthermore relates to the use of the compositions according to the invention for controlling parasites, in particular ectoparasites, in animals.
US08815268B2 Oat extracts: refining, compositions and methods of use
A simple and efficient method for the production of stable, clear, high-potency oat extracts is disclosed. The method employs the use of differential dissociation constants and ultrafiltration to stabilise extracts, prevent hazing, and prevent the loss of functional activity as an anti-irritant and anti-oxidant. Also disclosed are compositions of oat extracts derived from whole oat grains and oatmeal. Further disclosed are compositions of oat extracts for use in cosmetic, nutraceutical, therapeutic medical and veterinary preparations.
US08815266B2 Peptide derivatives useful in the treatment, care or cleansing of the skin, mucosae, scalp or nails
The invention relates to peptide derivatives of general formula (I): R1-AA1-AA2-R3-AA4-R2  (I) their stereoisomers, mixtures thereof, and their cosmetically or pharmaceutically acceptable salts, a method for obtaining them, cosmetic or pharmaceutical compositions containing them and their use for the treatment, care and/or cleansing of those conditions, disorders and/or pathologies of the skin, mucosae, scalp and/or nails resulting from microorganism proliferation or being at risk of microorganism proliferation.
US08815260B1 Treatment of restenosis and stenosis with dasatinib
A method for treating or inhibiting artery obstructive disease, such as restenosis after angioplasty and stenting procedures and stenosis after coronary artery bypass surgery, in a subject by administering to the subject a therapeutically effective amount of dasatinib or a derivative thereof. Also provided are drug-eluting medical devices, including stents, having a therapeutically effective amount of dasatinib.
US08815254B2 Method of detoxification
The present invention relates to a method of detoxifying bacterial cytolysins such as pneumococcal pneumolysin, utilizing chemical cross-linking compounds.
US08815250B2 Clotting factor-Fc chimeric proteins to treat hemophilia
The invention relates to a chimeric protein comprising at least one clotting factor and at least a portion of an immunoglobulin constant region. The invention relates to a method of treating a hemostatic disorder comprising administering a therapeutically effective amount of a chimeric protein wherein the chimeric protein comprises at least one clotting factor and at least a portion of an immunoglobulin constant region.
US08815246B2 Fc receptor binding proteins
This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.
US08815238B2 Methods for Preparing TACI-immunoglobulin fusion proteins
Molecules that interfere with the binding of a tumor necrosis factor receptor with its ligand, such as a soluble receptor, have proven usefulness in both basic research and as therapeutics. The present invention provides improved soluble transmembrane activator and calcium modulator and cyclophilin ligand-interactor (TACI) receptors.
US08815235B2 Tissue-specific imaging and therapeutic agents targeting proteins expressed on lung endothelial cell surface
Methods of delivering an agent in a tissue-specific manner, particularly lung tissue, by targeting a protein expressed on the endothelial cell surface, are described. The methods can be used for detecting, imaging and/or treating pathologies, as well as for diagnostics.
US08815232B2 Compositions and methods for treating cancer
The present invention is based, in part, on our discovery of compositions and methods that can be used to systemically deplete arginine and thereby treat arginine-dependent cancers. Our studies indicate that administering a composition that depletes arginine directly to the patient's small intestine will provide effective treatment for arginine-dependent cancers. Moreover, the methods can be carried out in such a way that various sources of arginine are restricted and side effects are minimized. For example, to deplete arginine, one can not only administer an arginine-depleting enzyme directly to the intestinal lumen but can also inhibit endogenous production of arginine, reduce arginine production by intestinal bacteria and limit arginine intake. To minimize side effects, one can inhibit protein breakdown, which may occur as a compensatory mechanism, provide systemic NO from a nitric oxide donor, provide a pressor peptide, and/or provide prostacycline or an analog thereof.
US08815228B2 Alloplastic injectable dermal filler and methods of use thereof
A composition comprising an alloplastic injectable suspension for use as a dermal filler comprising a biocompatible and pliable material and a physiologically acceptable suspending agent is provided. A method of making a composition comprising an alloplastic injectable suspension for use as a dermal filler comprising a biocompatible and pliable material and a physiologically acceptable suspending agent, said method comprising admixing a biocompatible and pliable material with a physiologically acceptable suspending agent, is also provided. A method of augmenting soft tissue to provide long-term reduction of a skin defect, said method comprising stimulating collagen beneath the skin defect is further provided. In an embodiment of the method of augmenting soft tissue, the stimulation of collagen production is effected by injecting into the deep reticular dermis an a dermal filler, said dermal filler being an alloplastic injectable suspension and comprising a biocompatible and pliable material and a physiologically acceptable suspending agent.
US08815227B2 Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom
The present invention provides, among other things, polymeric reagents suitable for reaction with biologically active agents to form conjugates, the polymeric reagents comprising one or more polymer chains and a plurality of hydroxyapatite-targeting moieties, and optionally the reagents include one or more degradable linkages that serve to divide the polymer chains into polymer segments having a molecular weight suitable for renal clearance.
US08815214B2 Fluorescent imaging agents
Provided is a family of intramolecularly quenched imaging agents for use in both in vivo and in vitro imaging that contain at least one enzymatically cleavable oligopeptide and two fluorophores or a fluorophore and a quencher. When subjected to proteolytic cleavage, at least one fluorophore is unquenched and becomes capable of producing a fluorescent signal upon excitation with light of an appropriate wavelength. Also provided are in vivo and in vitro imaging methods using such imaging agents.
US08815212B2 Nanocarriers for imaging and therapy applications
Nanocarriers and methods of preparation and use of nanocarriers are presented. In some embodiments, a nanocarrier composition comprises an organic liquid comprising a plurality of nanoparticles dispersed therein; and a coating material disposed around the exterior surface of the organic liquid. Biological tissue may be imaged or treated by coming into contact with a nanocarrier composition, and, at least in some embodiments, irradiated.
US08815204B2 Method of preparing material for lithium secondary battery of high performance
Provided is a method for preparing a lithium mixed transition metal oxide, comprising subjecting Li2CO3 and a mixed transition metal precursor to a solid-state reaction under an oxygen-deficient atmosphere with an oxygen concentration of 10 to 50% to thereby prepare a powdered lithium mixed transition metal oxide having a composition represented by Formula I of LixMyO2 wherein M, x and y are as defined in the specification. Therefore, since the high-Ni lithium mixed transition metal oxide having a given composition can be prepared by a simple solid-state reaction in air, using a raw material that is cheap and easy to handle, the present invention enables industrial-scale production of the lithium mixed transition metal oxide with significantly decreased production costs and high production efficiency. Further, the thus-produced lithium mixed transition metal oxide is substantially free of impurities, and therefore can exert a high capacity and excellent cycle stability, in conjunction with significantly improved storage stability and high-temperature stability.
US08815201B2 Process for regenerating a reforming catalyst
The present invention is directed to an in situ process for regenerating a reforming catalyst within a reactor by: (a) removing a carbon containing deposit from the reforming catalyst, (b) contacting the reforming catalyst with oxygen under catalyst rejuvenation conditions to provide a rejuvenated catalyst, (c) purging a portion of the oxygen from the rejuvenated catalyst such that residual oxygen is retained within the reactor, and (d) introducing hydrogen into the reactor at a rate to provide a reactor temperature increase in the range from 25 to 45° F.
US08815198B2 Method of purifying gas streams
A method of purifying a gas stream formed from a process wherein a glyceride containing raw material is converted to hydrocarbon paraffins. The gas stream contains hydrogen or carbon dioxide as a major component and at least one sulphurous component selected from sulphide compounds as an impurity. The gas is contacted with an acidic aqueous wash solution of transition metal ions capable of binding to sulphide ions. A significant portion of the sulphide compounds contained in the gas are bound into practically insoluble transition metal sulphide compounds to remove sulphide compounds from the gas to produce a purified gas. The obtained purified gas is recovered. The method efficiently lowers sulphide concentrations to ppm or sub-ppm level and it can be implemented on an industrial scale with low investment costs. The metal can be recovered.
US08815192B1 Cyclical system and method for removing and storing carbon dioxide obtained from a waste gas source
A cyclical system that uses a metal hydroxide to produce a metal carbonate, remove carbon dioxide from a waste gas source, and produce more metal hydroxide needed for the beginning of the cycle. Initially, the metal hydroxide is mixed with waste gases in a carbon dioxide scrubber. The scrubber reacts the carbon dioxide with the metal hydroxide to produce a metal carbonate. Some of the metal carbon is removed, therein removing carbon dioxide from the environment. Some of the metal carbonate is heated to produce metal oxide and carbon dioxide. The carbon dioxide is drawn away. Oxygen is introduced into the reaction chamber. The oxygen reacts with the metal oxide to produce an oxidized metal oxide and heat. The oxidized metal oxide is reduced with an acid and volatile base to produce metal hydroxide. The metal hydroxide is recycled. The acid is regenerated. The volatile base is recovered and recycled.
US08815191B2 Process for preparing catalysts involving the regeneration of metal carbonate precipitants
A process for manufacturing a catalyst composition includes the steps of (i) combining one or more soluble metal compounds with a solution of an alkaline metal carbonate precipitant to form a precipitate of insoluble metal carbonates, (ii) processing the insoluble metal carbonates into a catalyst or catalyst precursor with the evolution of carbon dioxide, (iii) recovering at least a portion of the evolved carbon dioxide, and (iv) reacting the recovered carbon dioxide with a suitable alkaline metal compound in an absorber column to generate an alkaline metal carbonate, wherein at least a portion of the generated alkaline metal carbonate is used as a precipitant in step (i).
US08815178B2 Integrated device for surface-contact sampling, extraction and electrochemical measurements
The invention relates to a device and method for non-invasive detection of an analyte in a fluid sample. In one embodiment, the device comprises: a collection chamber containing an absorbent hydrogel material; a fluidic channel connected to the collection chamber; a sensing chamber connected to the fluidic channel, wherein the device is comprised of a compressible housing that allows transfer of fluid collected by the collection chamber to be transferred to be extracted and withdrawn to the sensing chamber upon compression of the device, wherein the sensing chamber contains a material that specifically detects the analyte and wherein the sensing chamber is operably linked to a processor containing a potentiostat that allows detection of the analyte using electrochemical sensing.
US08815174B2 Steam sterilizer
A sterilizer having a cassette for holding metal instruments or medical devices. The cassette includes a metallic container that defines a sterilization chamber. The container has at least one outer surface. A plurality of spaced-apart, elongated rails extend along the at least one outer surface of the container. Each of the rails includes a free, longitudinal edge wherein the edges of the rails lie in a first plane. An insulating shell encases the metallic container and the plurality of rails. An outer surface of the insulating shell lies in the first plane. A receiving unit includes a housing having an outer surface and an inner surface. The inner surface engages the edges of the rails and the outer surface of the insulating shell when the cassette is disposed within the inner housing. A plurality of spaced-apart elongated ribs extends along the outer surface of the housing.
US08815166B2 Process and apparatus for mixing two streams of catalyst
A process and apparatus for mixing streams of regenerated and carbonized catalyst involves passing a catalyst stream around an insert in a lower section of a riser. The insert fosters mixing of the catalyst streams to reduce their temperature differential before contacting hydrocarbon feed.
US08815165B2 Systems and methods for distributing particulate material into a particulate vessel and FCC units including the systems
A system for distributing particulate material into a particulate vessel includes a particulate material distributor for introducing the particulate material into the particulate vessel. The particulate material distributor includes a declined header that defines a plurality of orifices that are spaced along a length of the declined header for accommodating flow of particulate material from the declined header. The system also includes a vessel level controller for controlling a level of the particulate material in the particulate vessel. The vessel level controller controls flow of the particulate material through one or more of the orifices in the declined header through adjustment of the level of particulate material in the particulate vessel between the plurality of orifices in the declined header. A FCC unit including the system is also provided, along with a method for distributing particulate material into a particulate vessel using the system.
US08815162B2 Microelectronic sensor device for DNA detection
The invention relates to a microelectronic sensor device and a method for the investigation of biological target substances (20), for example oligonucleotides like DNA fragments. In one embodiment, the device comprises a reaction surface (RS) to which target specific reactants (10) are attached and which lies between a sample chamber (SC) and an array of selectively controllable heating elements (HE). The temperature profile in the sample chamber (SC) can be controlled as desired to provide for example conditions for a PCR and/or for a controlled melting of hybridizations. The reactant (10) and/or the target substance (20) comprises a label (12) with an observable property, like fluorescence, that changes if the target substance (20) is bound to the reactant (10), said property being detected by an array of sensor elements, for example photosensors (SE). The fluorescence of the label (12) may preferably be transferred by FRET to a different fluorescent label (22) or quenched if the target substance (20) is bound.
US08815161B2 Gas sensor
A gas-sensing element configured to measure a concentration of a specific component of a gas is mounted to a first circuit board which includes a driving circuit configured to drive the gas-sensing element. A moisture-proof material is disposed over at least one side of the first circuit board disposed in a tubular gas-sensing element case fixed to a sensor case. A gas-sensing chamber is defined by the first circuit board and an inner tubular surface of the gas-sensing element case, and opens at an open end of the gas-sensing element case to receive the gas to be monitored. A second circuit board which includes a control circuit configured to control the gas-sensing element via the driving circuit is fixed to a sensor case, and disposed in a position separate from the gas-sensing chamber such that the second circuit board is kept out of contact with the gas to be monitored.
US08815160B2 Chemical vapor sensor with improved temperature characteristics and manufacturing technique
A vapor sensor is constructed from a single glass filament less than 2 millimeters in diameter and greater than 1 millimeters in length, the filament having a first end and a second end separated by a long axis and comprising electrodes at each end, coated with a resilient material, and a first layer of conducting particles embedded in the resilient material and forming a conducting path between ends of the filament.
US08815158B2 Granular nanoparticles having bright fluorescence and giant raman enhancements
The present invention provides nanoparticles having bright fluorescence, where the total number of photons emitted from a single nanoparticle upon excitation with an excitation wavelength of the nanoparticle is at least 107, and giant Raman enhancements, where Raman signal for a molecule near a single nanoparticle increases at least 107 times. The nanoparticles of the invention comprise a plurality of crystallites that are each about 0.6 nm to about 10 nm in size. The present invention also provides methods for making the nanoparticles, which include mixing a matrix material with a reactant capable of being thermally reduced to form the nanoparticle; forming a mixed solid phase; and thermally reducing the mixed solid phase to form the nanoparticle.
US08815156B2 Sensor housing and reagent chemistry
A sensor comprises a sensor housing, having a channel; a porous substrate, in the channel; an analysis chemistry reagent, on the porous substrate; and a nozzle, in fluid connection with the channel. The porous substrate fills a cross section of the channel, and the cross-sectional area of the channel at the porous substrate is greater than the cross-sectional area at the nozzle.
US08815148B2 Magnesium-based alloy with improved combination of mechanical and corrosion characteristics
Multi-component magnesium-based alloy consisting essentially of about 1.0-15.0 wt. % of scandium, about 0.1-3.0 wt. % of yttrium, about 1.0-3.0 wt. % of rare-earth metal, about 0.1-0.5 wt. % of zirconium. Purity degree of magnesium base is not less of 99.995 wt. %. Impurities of Fe, Ni and Cu do not exceed 0.001 wt. % of everyone, the contents of other impurity in an alloy does not exceed 0.005 wt. %. The alloy demonstrates an improved combination of strength, deformability and corrosion resistance at room temperature. The alloy does not contain harmful and toxic impurities. The alloy can be used in the various practical applications demanding a combination of high strength, deformability and corrosion resistance, preferably in the field of medicine.
US08815145B2 Methods and systems for fabricating composite stiffeners with a rigid/malleable SMP apparatus
A method and apparatus for fabricating a composite part with a shape memory polymer (SMP) apparatus usable as both a rigid tool and as a bladder. The SMP apparatus may be heated until malleable, shaped, and then cooled in a desired rigid tool configuration. The composite material may be applied onto the SMP apparatus and then placed into a rigid external mold and heated to composite cure temperatures at which the SMP apparatus is malleable. In some embodiments, an impermeable sheet of material may also be placed over portions of the composite material to compress it against the SMP apparatus. A pressure differential may be induced which urges the SMP apparatus to compress the composite material against the rigid external mold. When the composite material is cured, the pressure differential may be equalized and/or reversed and the malleable SMP apparatus may be removed from within the composite part.
US08815141B2 Method for building three-dimensional models with extrusion-based additive manufacturing systems
A method for building a three-dimensional model with an extrusion-based additive manufacturing system having an extrusion head, the method comprising depositing a consumable material from a liquefier assembly at an extrusion rate to substantially normalize a meniscus height within the liquefier assembly.
US08815139B2 Method and apparatus for forming flared tube ends
A method for forming a flare in the end of a flexible tube comprises heating the end of the flexible tube to a near-melted state, inserting the end of the flexible tube into a flare-forming die with a flare forming portion, and pressing a mandrel into the end of the flexible tube, thereby pressure forming a flare in the end of the flexible tube.
US08815138B2 Method of producing a recoil pad for a weapon
A recoil pad having a pad in which the elastomer contains a plurality of pockets having one or more pocket characteristics adjustable over the entirety or portions of the pad to achieve recoil pad characteristics which can be incrementally variably matched to the recoil energy characteristics and recoil energy transfer characteristics of a particular target stock.
US08815134B2 Process for manufacturing polyolefin films
A process for manufacturing a film of ultra-high molecular weight polyolefin comprising: (a) subjecting a starting ultra-high molecular weight polyolefin with a weight average molecular weight of at least 500 000 gram/mole in powder form to a compacting step using an isobaric press; and (b) subjecting the compacted polyolefin to a rolling step and at least one stretching step under such conditions that at no point during the processing of the polymer its temperature is raised to a value above its melting point. The process allows for the manufacture of ultra-high molecular weight polyolefin films of high quality.
US08815132B2 Method of configuring a patch body
A patch for a structure has a rework area with an inconsistency formed therein. The patch comprises a patch body having at least two regions including a fail-safe region and a safe-life region encompassing the fail-safe region. The safe-life region has a mode I interlaminar fracture toughness that is less than the mode I interlaminar fracture toughness of the fail-safe region.
US08815131B2 Apparatus and method for fabricating antimicrobial hybrid materials of natural product and carbon nanomaterials
The present disclosure relates to an apparatus and a method for fabricating an antimicrobial hybrid material of a natural antimicrobial particle and a carbon nanomaterial, capable of fully utilizing the antimicrobial property of a natural antimicrobial material and a carbon nanomaterial by maximizing adsorption of the natural antimicrobial material on the carbon nanomaterial.
US08815130B2 Method for producing a lens
A structure for pattern formation adapted for optically forming a pattern, characterized by comprising: a photocatalyst-containing layer provided on a substrate, the photocatalyst-containing layer containing a material of which the wettability is variable through photocatalytic action upon pattern-wise exposure.
US08815129B2 Device and method for forming lens
In order to realize a device and a method each capable of forming a lens with high accuracy and low costs, a lens forming device of the present invention includes a metal mold, an insulating substrate, a stage, a power source, a switch, and a UV radiating device. Dielectric resin is supplied onto the insulating substrate and a transfer surface of the metal mold is pressed to the dielectric resin so as to transfer a lens shape to the dielectric resin. At that time, the power source applies a voltage on the metal mold to generate an electric field between the metal mold and the insulating substrate so that an electrostatic attraction causes the dielectric resin to be attracted toward the transfer surface of the metal mold while the top of the dielectric resin has a sharp cuspate shape. Consequently, bubbles are less likely to be invade between the transfer surface and the dielectric resin, allowing transferring a highly accurate lens shape to the dielectric resin.
US08815122B2 Polycrystalline scintillator for detecting soft X-rays
A polycrystalline scintillator for detecting soft X-rays, which comprises Ce as a light-emitting element and at least Y, Gd, Al, Ga and O, and has a garnet crystal structure, and a composition represented by the general formula of (Y1-x-zGdxCez)3+a(Al1-uGau)5-aO12, wherein 0≦a≦0.1, 0.15≦x≦0.3, 0.002≦z≦0.015, and 0.35≦u≦0.55, with 0.05-1 ppm by mass of Fe and 0.5-10 ppm by mass of Si by outer percentage, a ratio μ50/μ100 of 3 or more, wherein μ50 is an absorption coefficient of X-rays at 50 keV, and μ100 is an absorption coefficient of X-rays at 100 keV, and afterglow of 800 ppm or less after 3 ms from the termination of X-ray irradiation.
US08815118B2 Lock and key colloids and methods of manufacture
A method and system for assembling building blocks of colloidal particles and also for shaping of colloids for self-assembly for manufacturing, processing and formation of compositions of matter. A first type of particle is selected as a “key” particle constructed to mate with a “lock” particle, the binding arising from depletion forces. A variety of shapes can be used to carry out this method and system to create compositions of matter. Colloids can be shaped by controlled deformation of multiphase colloid particles.
US08815114B2 Phenol stabilizers for fluoroolefins
The present invention relates to compositions comprising at least one fluoroolefin and an effective amount of stabilizer that may be at least one phenol or a mixture of at least one phenol with other stabilizers. The stabilized compositions may be useful in cooling apparatus, such as refrigeration, air-conditioning, chillers, and heat pumps, as well as in applications as foam blowing agents, solvents, aerosol propellants, fire extinguishants, and sterilants.
US08815110B2 Composition and method for polishing bulk silicon
The invention provides a polishing composition comprising (a) silica, (b) one or more compounds that increase the removal rate of silicon, (c) one or more tetraalkylammonium salts, and (d) water, wherein the polishing composition has a pH of about 7 to about 11. The invention further provides a method of polishing a substrate with the polishing composition.
US08815105B2 Method using block copolymers for making a master mold for nanoimprinting patterned magnetic recording disks with chevron servo patterns
A method for making a master mold used to nanoimprint patterned magnetic recording disks that have chevron servo patterns with minimal defects uses directed self-assembly of block copolymers. A pattern of chemically modified polymer brush material is formed on the master mold substrate. The pattern includes sets of slanted stripes and interface strips between the sets of slanted stripes. A block copolymer material is deposited on the pattern, which results in directed self-assembly of the block copolymer as lamellae perpendicular to the substrate that are formed into alternating slanted stripes of alternating first and second components of the block copolymer. This component also forms on the interface strips, but as a lamella parallel to the substrate. One of the components is then removed, leaving the remaining component as a grid that acts as a mask for etching the substrate to form the master mold. The disks nanoimprinted by the master mold have reduced defective areas in the transition regions of the chevron servo patterns.
US08815104B2 Copper-assisted, anti-reflection etching of silicon surfaces
A method (300) for etching a silicon surface (116) to reduce reflectivity. The method (300) includes electroless deposition of copper nanoparticles about 20 nanometers in size on the silicon surface (116), with a particle-to-particle spacing of 3 to 8 nanometers. The method (300) includes positioning (310) the substrate (112) with a silicon surface (116) into a vessel (122). The vessel (122) is filled (340) with a volume of an etching solution (124) so as to cover the silicon surface (116). The etching solution (124) includes an oxidant-etchant solution (146), e.g., an aqueous solution of hydrofluoric acid and hydrogen peroxide. The silicon surface (116) is etched (350) by agitating the etching solution (124) with, for example, ultrasonic agitation, and the etching may include heating (360) the etching solution (124) and directing light (365) onto the silicon surface (116). During the etching, copper nanoparticles enhance or drive the etching process.
US08815103B2 Process for preparing an optical preform
A method of preparing an optical preform includes the steps of: a) etching an optical preform to remove a portion of an oxide material deposited on the preform by using a gas comprising an etchant gas containing fluorine at a sufficient temperature and gas concentration to create a redeposited germanium containing compounds contamination such as GeOx in the remaining oxide material; and b) cleaning the etched preform using a cleaning gas containing at least one halogen gas at a sufficient temperature and gas concentration to remove the redeposited germanium containing compound contamination without any substantial further contamination of the remaining deposited oxide material. Preferably the halogen is either chlorine or bromine.
US08815101B2 Sediment removal tank and system
This invention relates generally to the field of separation of heterogeneous mixtures and, more particularly to a solid-liquid separating tank and system.A settlement tank including: a tank wall defining a tank inner space; an internal wall structure in the inner space and defining a fluid flow path from a center of the inner space to a fluid outlet at the tank wall; and a plurality of drainage pipes having an open internal end and an outer end connected to a drainage manifold, wherein the open internal end is positioned at a bottom of the inner space to remove gravity decanted sediment and hydrostatically decanted water from the inner space.
US08815093B2 Method and system for providing effluent from at least one wastewater treatment plant
Exemplary embodiments of using effluent from a wastewater treatment plant are provided, where treated wastewater can exploit geothermal energy while delivering usable thermal energy to buildings by passing through an effluent distribution system including mains. The effluent distribution system mains can also recover the effluent used in each building and return the thermally exploited effluent to one or more ecological recharge basins, where at each basin the mains can join an infrastructure to distribute effluent to vegetation or exploit geothermal energy throughout the basin before redistributing the geothermally regulated effluent to buildings, or export the effluent to a network of EDS, or import effluent from a network of EDS.
US08815091B2 Spiral wound membrane module for forward osmotic use
A spiral wound membrane module for forward osmotic use is disclosed. The membrane module may generally include a forward osmosis membrane in a spiral wound configuration. The module may include two inlets and two outlets, and may define first and second fluid flow paths. The inlets to each of the fluid flow paths may be generally isolated so as to prevent mixing. In some embodiments, the membrane module may include a distributer region and a collector region.
US08815090B2 Filter with water separation device
A filter, filter element and filter assembly are provided. The filter includes a water separating device for separating water from a dirty fluid flow. The water separator includes a fluid flow path that varies in cross-sectional area to vary pressure of the fluid therethrough. A top portion of the water separator is formed as a structurally independent piece from a bottom portion of the water separator. The top portion may be permanently or releasably secured to filter media of the filter via an end cap coupled to an end of the filter media. The bottom portion may be integrally or releasably secured to a housing of the filter. The bottom portion may also be integrally formed with a center tube upon which a filter element mounts.
US08815089B2 Wastewater purification with nanoparticle-treated bed
Nanoparticle-treated particle packs, such as sand beds, may effectively filter and purify liquids such as waste water. When tiny contaminant particles in waste water flow through the particle pack, the nanoparticles will capture and hold the tiny contaminant particles within the pack due to the nanoparticles' surface forces, including, but not necessarily limited to van der Waals and electrostatic forces. Coating agents such as alcohols, glycols, polyols, vegetable oil, and mineral oils may help apply the nanoparticles to the particle surfaces in the filter beds or packs.
US08815086B2 Fluid filter assembly
A fluid filter assembly prevents the filter from moving when fluid is not flowing through the filter. The filter assembly of the invention includes a mounting ring mountable in the filter opening. The mounting ring has a mounting interface, which includes an axially extending portion and a radially outwardly extending flange that has a diameter greater than the filter opening. A rib extends radially outwardly from and circumscribes the ring. The rib is seatable within an annular groove defined within the filter housing and circumscribing the filter opening. When the rib is positioned in the groove, the filter is releasably secured in the opening.
US08815077B2 Electrochemical sensor for measuring the oxygen partial pressure in a process fluid and a method for testing its function
An electrochemical sensor for measuring the oxygen partial pressure in a process fluid, comprises an electrolyte-filled sensor body, which is covered on one side charged with the process fluid by an oxygen-permeable membrane, a cathode on the membrane, an annular guard electrode surrounding the cathode, which in measuring operation lies at the same potential as the cathode, an anode charged by the electrolyte in the sensor body, a reference electrode charged by the electrolyte in the sensor body, wherein between the anode and cathode a voltage can be applied, which is controlled between the cathode (8) and reference electrode at a constant polarization voltage and the measuring sensor current flowing in measuring operation between the cathode and anode is a measure for the oxygen partial pressure in the process fluid, and a test voltage source which can be switched in a testing mode between the cathode and guard electrode for producing test oxygen in the electrolyte and/or in the process fluid between the cathode and guard electrode for testing the function of the sensor.
US08815075B2 Water electrolysis system and method of operating same
A water electrolysis system includes a water electrolysis apparatus for electrically decomposing water to generate oxygen and high-pressure hydrogen having a pressure higher than the oxygen, a gas-liquid separator connected to a hydrogen pipe which discharges the high-pressure hydrogen from the water electrolysis apparatus, for separating water contained in the high-pressure hydrogen, a high-pressure hydrogen outlet pipe for delivering the high-pressure hydrogen separated from water from the gas-liquid separator, a water drainage line for discharging the water from the gas-liquid separator, and a gas depressurizing line connected to the gas-liquid separator, for degassing the gas-liquid separator before the water is discharged from the water drainage line into the water drainage line.
US08815073B2 Web pressure welding method, pressure welding device, power supply method, power supply device, continuous electrolytic plating apparatus and method for manufacturing web with plated coating film
A web pressure welding method for pressure welding, with respect to a running web, a first belt-shaped annular body which contact surface rotates with running of at least one web, where an area pressure for pressure welding to the web side is applied on the contact surface of the first belt-shaped annular body.
US08815068B2 Mixing method and system for increased coalescence rates in a desalter
The present invention relates to crude oil-water separation processes, specifically desalting in a petroleum refinery. More particularly, the present invention relates to a method and system for increase coalescence rates of water drops in a desalter.
US08815067B2 Electrodeionization device and method comprising control of the electric current by measurement of ion-exchange material expansion
Device for the removal of ions from a polar liquid, e.g. water, comprising at least one compartment which comprises at least one inlet for an entering polar liquid flow and at least one outlet for an outgoing deionized liquid flow, in which said compartment an electrochemically regenerable ion-exchange material fills a zone through which zone a liquid flow is able to pass, the device being characterized in that it comprises one sensor of at least one dimensional change of the ion-exchange material. The sensor can comprise a photo-sensor or a sensor of mechanical stress. Preferably an apparatus connected to the sensor is able to analyze this dimensional change and to control the electric current. Method of using said device, whereby the electrical current applied to the device is controlled according to the expansion of the resin.
US08815059B2 System and/or method for heat treating conductive coatings using wavelength-tuned infrared radiation
Certain example embodiments relate to systems and/or methods for preferentially and selectively heat treating conductive coatings such as ITO using specifically tuned near infrared-short wave infrared (NIR-SWIR) radiation. In certain example embodiments, the coating is preferentially heated, thereby improving its properties while at the underlying substrate is kept at low temperatures. Such techniques are advantageous for applications on glass and/or other substrates, e.g., where elevated substrate temperatures can lead to stress changes that adversely effect downstream processing (such as, for example, cutting, grinding, etc.) and may sometimes even result in substrate breakage or deformation. Selective heating of the coating may in certain example embodiments be obtained by using IR emitters with peak outputs over spectral wavelengths where the conductive coating (or the conductive layer(s) in the conductive coating) is significantly absorbing but where the substrate has reduced or minimal absorption.
US08815058B2 Extractive distillation of AsF5 and PF5 using HF
Arsenic can be an impurity in phosphorous pentafluoride production processes. It is desirable to remove arsenic from phosphorous pentafluoride prior to using of the phosphorous pentafluoride in the production of lithium hexafluorophosphate. The present technology provides methods of removing arsenic from phosphorous pentafluoride by extractive distillation.
US08815057B2 Perforated film clothing
A fabric for a papermaking machine is configured as a belt, the two side edges of which are configured in each case as closed lines. Furthermore, the belt is formed in one layer from a solid material and has pores which form passages between the two surfaces of the belt. The belt has regions with a width of approximately 400 micrometers (μm) or less. These regions extend in the longitudinal direction over the entire circumference of the belt, transversely with respect to the side edges, and include no pores formed therein.
US08815055B2 Press felt for papermaking
Press felts for papermaking include a batt fiber layer and a base fabric. The batt fiber layer is integrated into the base fabric. The base fabric includes a ground warp yarn, a ground weft yarn, and an additional warp yarn. The ground warp yarn and the ground weft yarn include monofilament yarns, and the additional warp yarn includes a material different from a material forming the ground warp yarn. The additional warp yarn is arranged so that, when the base fabric is viewed in cross-section in a warp yarn direction, the additional warp yarn ascends toward a wet paper web-side surface of the base fabric and descends toward a roll-side surface of the base fabric, relative to the at least one ground warp yarn.
US08815054B2 Methods for making fibrous paper structures utilizing waterborne shape memory polymers
The invention relates to the making of a cellulosic fibrous structure by adding a waterborne shape memory polymer to cellulosic papermaking slurry and forming a web from the waterborne shape memory polymer containing slurry. The web can be optionally foreshortened.
US08815053B2 Method of treating liquid flows at a chemical pulp mill
A method of treating and utilizing liquid flows at a chemical pulp mill including stages for: a) chemical pulp is produced in an alkaline cooking process, b) the brown stock generated in the cooking is treated, said treatment comprising washing of the stock and preferably oxygen delignification and subsequent washing of the stock, c) a bleaching process for the brown stock, the bleaching sequence comprising at least one stage using chlorine dioxide and additionally at least one oxidizing bleaching stage and having at least two washing stages for treating the stock with liquids and for producing filtrates, and d) filtrates from stage c) are purified at an effluent treatment plant of the chemical pulp mill, which comprises at least biological treatment, for obtaining purified effluent. The method further includes a stage e), where the purified effluent with a color of 200 mg/l (Pt color) or more and a COD value of over 150 mg/l is used as pulp treatment liquid in stage c).
US08815049B2 Method and apparatus for reduction of contaminants in evaporator distillate
A method and apparatus for producing high purity distillate in evaporators is useful for evaporation of waters where volatile silica or organic compounds are encountered such as in production of hydrocarbons from geological formations. An evaporator having a contaminant reduction system is provided. The contaminant reduction system includes an upflow first mist eliminator portion to remove entrained liquid droplets and produce an intermediate purity water vapor stream. A continuous spray system provides a spray of dilute caustic solution in a selected spray configuration for mass transfer contact with the passing intermediate purity water vapor stream, to remove volatile silica compounds therefrom, and produce a partially decontaminated steam stream having mist particles therein. An upflow second mist eliminator portion is provided to remove the residual mist particles, and produce a high purity water vapor stream. The high purity water vapor stream is condensed to provide a high purity distillate stream.
US08815044B2 Method of manufacturing spars, longerons and fuselage beams having a variable H cross-section
A beam of fiber-reinforced curable thermosetting composite material is preliminarily assembled in an uncured condition. The beam is placed between two forming tools, namely a lower and an upper tool, shaped in such a way as to give the lower and upper flanges a predetermined shape, at least one of the flanges having a non-rectilinear profile viewed in a longitudinal vertical plane. Two longitudinally elongate rigid inserts are placed between the flanges at the sides of the web and are covered in respective airtight tubular bags. The spaces between the upper tool and the lower tool on the two opposite longitudinal sides are sealed. The open opposite ends of the tubular bags are also sealed in such a manner that the pressure applied in an autoclave during the step of curing causes the tubular bags to swell and presses them against the two opposite faces of the web and against the flanges of the beam. On completion of curing, the upper forming tool is removed and the inserts are extracted sideways.
US08815043B2 Dry lamination method and laminate obtained by using the same
Provided is a dry lamination method, and a laminate having superior appearance obtained by the method. The method in which an adhesive having a solid matter content of 35 wt % or more diluted in a solvent is applied onto a film according to a gravure process, the solvent is volatilized, and the resulting film is adhered with another film to obtain a laminate, wherein the adhesive is applied by: a gravure cylinder in which the screen number of gravure cylinder is 135 to 270 lines/inch and cell volume is 10 to 30 cc/m2; a gravure cylinder which is engraved by an electronic engraving machine to have a stylus angle of 120 to 140° and the screen number of gravure cylinder of 120 to 270 lines/inch; or a ceramic roll in which the screen number of gravure cylinder is 135 to 350 lines/inch and cell volume is 10 to 30 cc/m2.
US08815039B2 Application of a processing pin to a gemstone which is to be cut or polished
A next processing pin is applied as a follow-on pin to a stone, wherein the stone is held by a preceding pin and fixed to the stone by way of a first adhesive bonding location. The preceding pin is separated from the stone. The follow-on pin is fixed to the stone by way of a second adhesive bonding location spaced from the first adhesive bonding location. The follow-on pin frontally receives a fluid adhesive at a spacing from the stone and the spacing between the adhesive-coated front end and the stone is reduced until the adhesive front end contacts the stone. The adhesive is hardened at the contact location as the second adhesive bonding location and heat is transferred by way of the preceding pin to the first adhesive bonding location A force component is exerted on the preceding pin to release the pin from the stone and to hold the stone with the next pin.
US08815037B2 Method of manufacturing absorbent articles, apparatus for manufacturing absorbent articles and disposable pant
A method of manufacturing absorbent articles (9) includes feeding a longitudinal web (1) of web material having openings (16) such that spaced apart, opposing margins (18) of web material are formed between the respective opening and opposing longitudinal edges of the web material; carrying out a folding action (20) of folding the web about itself along its longitudinal direction; carrying out a second (30) folding action of folding at least a portion of the web along its longitudinal direction; after the second folding action, forming a joint (46) in the web, the joint being formed at least in a part of the region in which the opposing margins have been brought together by the second folding action; finally separating (8) the web through the joint to separate an individual absorbent article from the end of the web.
US08815027B2 Fe-based shape memory alloy and its production method
An Fe-based shape memory alloy comprising 25-42 atomic % of Mn, 12-18 atomic % of Al, and 5-12 atomic % of Ni, the balance being Fe and inevitable impurities, and an Fe-based shape memory alloy comprising 25-42 atomic % of Mn, 12-18 atomic % of Al, and 5-12 atomic % of Ni, as well as 15 atomic % or less in total of at least one selected from the group consisting of 0.1-5 atomic % of Si, 0.1-5 atomic % of Ti, 0.1-5 atomic % of V, 0.1-5 atomic % of Cr, 0.1-5 atomic % of Co, 0.1-5 atomic % of Cu, 0.1-5 atomic % of Mo, 0.1-5 atomic % of W, 0.001-1 atomic % of B and 0.001-1 atomic % of C, the balance being Fe and inevitable impurities.
US08815024B2 Steel plate or steel pipe with small occurrence of Bauschinger effect and methods of production of same
The present invention provides steel plate or steel pipe with small occurrence of the Bauschinger effect and methods of production of the same, particularly steel pipe used for steel pipe for oil wells or line pipe with a small drop in the compression strength in the circumferential direction due to the Bauschinger effect when expanded and methods of production of the same, that is steel plate or steel pipe with small occurrence of the Bauschinger effect characterized by having a dual-phase structure substantially comprising a ferrite structure and fine martensite which is dispersed in the ferrite structure. Further, this steel plate or steel pipe contains, by mass %, C: 0.03 to 0.30%, Si: 0.01 to 0.8%, Mn: 0.3 to 2.5%, P: 0.03% or less, S: 0.01% or less, Al: 0.001 to 0.01%, and N: 0.01% or less and a balance of iron and unavoidable impurities.
US08815023B2 Boronization process and composition with improved surface characteristics of metals
Embodiments of the disclosed technology provide methods of boronizing titanium and other metals and metal alloys. The method proceeds, in an embodiment of the disclosed technology, by using a boron source, and placing it in a heated environment, followed by a reduced pressure environment, as is described in the disclosure. In a solid phase embodiment of the disclosure, boronized stainless steel alloys are produced having zero galling at 17,000 psi.
US08815022B2 Method for surface treating a heat exchanger, surface treatment agent, and aluminum heat exchanger
A method for surface treating a heat exchanger and an aluminum heat exchanger obtained from this method are provided that can effectively suppress the foul odor characteristic to flux that emanates following degradation of a hydrophilic coating film and a chemical conversion coating film in a non-corrosive flux brazed heat exchanger on which flux easily remains. The method for surface treating a non-corrosive flux brazed heat exchanger made of an aluminum material conducts a pickling treatment step, a chemical conversion treatment step, and a deodorizing treatment step on the heat exchanger, in which the acidic cleaning agent contains nitric acid and sulfuric acid as well as a predetermined amount of ferric salt, and the surface treatment agent contains silica grains coated by a vinyl alcohol polymer and polyallylamine resin such that the total content of the silica grains and the vinyl alcohol polymer is a predetermined amount.
US08815019B2 Bonding wire for semiconductor
It is an object of the present invention to provide a multilayer wire which can accomplish both ball bonding property and wire workability simultaneously, and which enhances a loop stability, a pull strength, and a wedge bonding property. A semiconductor bonding wire comprises a core member mainly composed of equal to or greater than one kind of following elements: Cu, Au, and Ag, and an outer layer formed on the core member and mainly composed of Pd. A total hydrogen concentration contained in a whole wire is within a range from 0.0001 to 0.008 mass %.
US08815015B2 Apparatus and method for fabricating organic light emitting diode display device
An apparatus and method for fabricating an organic light emitting diode display device are provided. The apparatus for fabricating an organic light emitting diode display device includes a chamber, a mask disposed in the chamber to mount a substrate on the upper surface thereof and having a certain pattern of openings, a deposition material source disposed under the mask and supplying a deposition material to the mask through the openings of the mask to form a layer on the substrate, and a holding unit pressing the substrate toward the mask. The holding unit includes a member that is capable of being deformed according to a deformed shape of the substrate such that the mask closely contacts the substrate.
US08815007B2 Alkoxylated polyamines and polyetheramine polyol compositions for foam control
This invention relates to novel compounds derived from the reaction of diamines or polyamines with alkylene oxides. The invention also relates to novel compounds derived from the reaction of amine terminated polyethers with epoxide functional compounds. The novel compounds of the invention are particularly useful as wetting and foam control agents. The disclosed compounds exhibit exceptional antifoaming and defoaming activity while simultaneously reducing the dynamic surface tension when incorporated at low levels in water-based systems.
US08815004B2 Tailings stream treatment processes
A process for treating a tailings stream comprises (a) contacting (1) a gelling agent and (2) an activator with said tailings stream to produce a gel; (b) entrapping solids including sand and clay, and other solid particles with the gel; and (c) allowing the gel to strengthen and solidify to produce a trafficable deposit; wherein the tailings stream comprises water and solids, which solids comprise sand, clay and other solids particles, and wherein 5% by volume to 100% by volume of the solids have a particle size less than 0.05 mm, based on the total volume of the solids. The process may further comprises spreading the gel produced in step (a) or the trafficable deposit produced in step (c) over a surface. The present invention is particularly useful to treat tailings streams produced in processes to extract bitumen from oil sands ores.
US08815001B2 Compound for manufacturing watermark in a textile sheet material and the corresponding composition, material, method and use
The invention relates to a compound for manufacturing watermark in a textile sheet material and the corresponding composition, material, method and use. The compound for manufacturing a watermark in a textile sheet material of formula wherein X is hexamethylene, trimethylhexamethylene, isophorone, dicyclohexylmethyl, tetramethylxylylene, tetramethylenexylene, xylylene, trimethylhexamethylene, hydrogenated 4,4′-diphenylmethylene, 1,12-dodecylene, 1,5-2-methylpentylene; 1,4-butylene; 1,4-cyclohexylene, or a compound of formula R1 is a linear aliphatic C1-C12 alkyl radical or a branched aliphatic C3-C18 alkyl radical R2 is a radical of formula wherein R4 is methoxy or ethoxy R5 and R6 are H, methoxy, ethoxy, methyl or ethyl R7 is cyclohexyl, phenyl or aliphatic C3-C6 alkyl R3 is a linear aliphatic C1-C12 alkyl radical or a branched aliphatic C3-C18 alkyl radical n is 0 or 1.
US08815000B1 Solid inks comprising liquid crystalline materials
A solid ink composition used for ink jet printing. In particular, the solid inks comprise a liquid crystalline material that can be jetted in a molten, amorphous state at elevated temperatures, electrically poled to align the molecules in an intermediate liquid crystalline state at lower temperatures, and then frozen into a robust, high quality image upon cooling.
US08814998B1 Method of preparation and application for flame retarding composition
The present invention teaches a three-step method for an aqua based chemical composition for flame retardation. The composition comprises: Sodium Borate, Boric Acid, Guanylurea Phosphate, Hydrogen Peroxide, Magnesium Chloride, and Sodium Silicate. The referenced salts are dissolved in distilled water, and the resultant flame retarding solution is coated on substrate surfaces to be protected against flame retardation. The flame retarding composition solution from step-1 alone may be used on non-prepared substrate surfaces. The flame retarding composition solution fully satisfies the Federal Aviation Regulation (FAR) 25.853(a) vertical burn test, and Federal Aviation Regulation (FAR) 25.853(d) heat release test. The utility of the present invention extends to numerous commercial and non-commercial applications.
US08814995B2 Electrical screening device for structures near high voltage parts of electrostatic precipitators
An electrostatic precipitator having a collecting electrode plate assembly, including at least two electrode plates disposed substantially in a parallel to each other in the vertical plane within the electrostatic precipitator, forming a space between the collecting electrode plates, and a discharge electrode assembly interposed in said spaces, wherein the electrode assembly passing at least a supporting structure of the collecting electrode plate assembly. The supporting structure is provided with an electrical screening device at least in the area of the supporting structure facing said electrode assembly.
US08814991B2 Powder coating system with easily cleanable cyclone
A powder cyclone separator for use in a powder coating system is contemplated that is formed in two separate and separable sections. An upper section of the cyclone is mounted on a first frame and remains stationary. A lower section of the cyclone is mounted on a second frame that is movable laterally away from the first frame so that an operator has more ready access to clean interior surfaces of the upper section. Optionally, actuators may be provided to vertically raise and lower the cyclone lower section with respect to the cyclone upper section. Various optional alignment means are presented for aligning the cyclone upper and lower sections. Preferably, a control mechanism is mounted on the second frame which includes a switch that is manually operated by the user to raise and lower the lower section with respect to the upper section. This design allows an operator to see, and therefore verify, that virtually all internal surfaces of the cyclone have been effectively cleaned.
US08814989B2 Process for removing carbon dioxide (CO2) from a cycle gas system
A process for removing carbon dioxide (CO2) by means of an absorption medium from a cycle gas system, wherein the CO2 occurs within a process in which, in the gas phase, ethylene is oxidized by oxygen (O2) to ethylene oxide (EO) in the presence of a catalyst, in which, as by product, CO2 is generated, by using as absorption medium an aqueous solution of one or more amines, wherein, for further purification of the cycle gas stream obtained downstream of the CO2 absorption step, this cycle gas stream is brought into intimate contact with water to which no mineral acid and no higher glycol was added.
US08814988B2 Process and apparatus for recovering ammonia from a gas stream
The present invention relates to a process for the recovery of ammonia contained in a gaseous stream, said process comprising the following phases: (a) subjecting the gaseous stream containing ammonia to a washing with an aqueous washing solution having a pH lower than 7.0, with the formation of a purified gaseous stream and an aqueous solution containing an ammonium salt; (b) treating the aqueous solution containing the ammonium salt coming from phase (a) in a vertical falling film heat exchanger at a temperature from 50 to 250° C. and an absolute pressure ranging from 50 KPa to 4 MPa with the formation of a regenerated washing solution and a gaseous stream comprising NH3 and H2O; (c) recycling said regenerated washing solution to phase (a). The present invention also relates to equipment for effecting the above process.
US08814984B2 Process and apparatus for removing contaminants from a gas stream
A gas purification process for treating a gas stream includes supplying the gas stream to at least one membrane unit to produce a permeate stream and a retentate stream. The retentate stream contains a lower concentration of at least one of water, hydrogen sulfide, or carbon dioxide as compared to the gas stream. The retentate stream is supplied to a molecular sieve unit to remove hydrogen sulfide to produce a treated gas product stream.
US08814982B2 Tetrazole functionalized polymer membranes
The present invention discloses a new type of high selectivity UV-cross-linked tetrazole group functionalized polymer nanosieve (TZPIM) membranes, their preparation, as well as their use for gas and liquid separations. The UV-cross-linked TZPIM membrane showed more than 50% improvement in CO2/CH4 selectivity and more than 30% improvement in CO2/N2 selectivity compared to the uncross-linked TZPIM membrane for CO2/CH4 and CO2/N2 separations, respectively.
US08814981B2 Compression of carbon dioxide containing fluid
The present invention relates to a method of pressurizing a fluid comprising carbon dioxide, the method includes: obtaining the fluid from a unit for removing carbon dioxide from a process gas; compressing the fluid to a pressure above the critical pressure of carbon dioxide; and cooling the compressed fluid to a temperature above the critical temperature of carbon dioxide to produce a supercritical fluid. The invention further relates to an apparatus for pressurizing a fluid comprising carbon dioxide, the apparatus including: means for obtaining the fluid from a unit for removing carbon dioxide from a process gas; means for compressing the fluid to a pressure above the critical pressure of carbon dioxide; and means for cooling the compressed fluid to a temperature above the critical temperature of carbon dioxide to produce a supercritical fluid.
US08814979B2 Methods for the production of silver nanowires
Embodiments of the present invention are directed to novel methods for the solution-based production of silver nanowires by adaptation of the polyol process. Some embodiments of the present invention can be practiced at lower temperature and/or at higher concentration than previously described methods. In some embodiments reactants are added in solid form rather than in solution. In some embodiments, an acid compound is added to the reaction.
US08814977B2 Stabilized compositions comprising ammonium nitrate
Preferred aspects of the present invention provide ammonium nitrate compositions comprising ammonium nitrate and at least one stabilizing agent, and preferably a third compound. In certain preferred embodiments, the stabilizing agent, together with third compound, is present under conditions and in amounts effective to substantially reduce the detonation sensitivity of the composition and/or to otherwise improve a desired property of the composition.
US08814973B2 Air cleaner arrangements with end support for cartridge; components; and, methods
An air cleaner assembly is described and shown which includes a housing having an air flow inlet, an air flow outlet and a housing body and access cover. A serviceable filter cartridge is positioned within the housing. A projection/receiver arrangement providing for engagement between the cartridge and the access cover is provided. The projection/receiver arrangement can be configured in a manner that inhibits both cantilevered motion and rotational motion of the cartridge, once installed. An example projection/receiver arrangement is provided, which includes a serpentine receiving groove on the access cover and a serpentine projection on the filter cartridge.
US08814970B2 Trapping device that traps particles in vacuum atmosphere
A trapping device that traps a particle in a vacuum atmosphere includes a plurality of grooves arrayed on a surface of the trapping device. Each of the plurality of grooves has a shape that is obtained by replacing a bottom part of a U-groove is replaced with a V-groove.
US08814967B2 Abrasive article and method of making
An abrasive article includes a bonded abrasive having a body made of abrasive grains contained within a composite bond material. The composite bond material can include an organic material and a metal material. The body can also include a filler material made of a superabrasive material. In an embodiment, the filler material can have an average particle size at least about 10 times less than an average particle size of the abrasive grains.
US08814962B2 Engineered fuel storage, respeciation and transport
Techniques, systems and material are disclosed for thermochemical regeneration of biomass into renewable engineered fuel, storage of the renewable engineered fuel, respeciation of the renewable engineered fuel and transport. In one aspect, a method includes generating low density hydrogen fuel from biomass dissociation at a first location of a low elevation. The low density hydrogen fuel is self-transported in a pipeline to a second location at a higher elevation than the first location by traveling from the first location to the second location without adding energy of pressure. A high density hydrogen carrier is generated at the second location of higher elevation by reacting the low density hydrogen fuel with at least one of a carbon donor, a nitrogen donor and an oxygen donor harvested from industrial waste. The high density hydrogen carrier is delivered to a third location of a lower elevation than the second location while providing pressure or kinetic energy.
US08814955B2 Method for manufacturing lithium ion secondary battery, and packaging thereof containing pre-charged lithium ion secondary battery
There is provided a lithium ion secondary battery exhibiting a high capacity retention rate over a long period. There is also provided a method for manufacturing a lithium ion secondary battery including a positive electrode, a negative electrode containing a negative electrode active material layer containing a graphite, an aprotic electrolyte solution containing a sulfonate ester having at least two sulfonyl groups, and a packaging material including a laminate film involving the positive electrode, the negative electrode and the aprotic electrolyte solution, the method including: enclosing the positive electrode, the negative electrode and the aprotic electrolyte solution in the packaging material to fabricate a lithium ion secondary battery before pre-charge; pre-charging the lithium ion secondary battery; and opening the enclosure of the packaging material of the lithium ion secondary battery after pre-charge, thereafter vacuum sealing the packaging material, and regularly charging the lithium ion secondary battery after pre-charge, wherein the current for the pre-charge is 0.05 to 0.25 C, and the voltage thereof is 3.3 to 3.5 V.
US08814954B2 Method of manufacturing products having a metal surface
The method for manufacturing products having a metal surface by imparting microfeatures onto the metal surface. The method if further described as the steps of: creating a transfer tool from a microstructured intermediate fabricated from a microstructured prototype having microfeatures; and, transferring the microfeatures to said metal surface using the transfer tool.
US08814953B1 System and method for spray dyeing fabrics
A system and method are provided for dyeing fabric, the system including a dye spray station, a dye fixation station downstream of the dye spray station, and at least one rinse station downstream of the dye fixation station. The process includes opening the fabric with a spreader to maintain the fabric flat and taut, spraying the outer surfaces of the fabric with a dye, and exposing the fabric to atmospheric steam to chemically react and affix the dye to the fabric.
US08814948B2 Method for controlling an orthopedic knee joint
The invention relates to an orthopedic knee joint, comprising an upper part (2), on which upper connecting means (20) are disposed, a lower part (3) pivotally supported on the upper part (2), connecting means for orthopedic components (4), and a stop ( ) for delimiting an extension movement, wherein the stop (7) is configured displaceably and coupled to an adjusting device (64), which is coupled to a control device (6), which actuates the adjusting device (64) as a function of sensor data and changes the position of the stop (7).
US08814947B2 Deformable flap catch mechanism for occluder device
Devices, delivery systems, and delivery techniques for an occlusion device for closure of physical anomalies, such as an atrial septal defect, a patent foramen ovale (PFO), and other septal and vascular defects are described. Specifically, an occluder with a catch member that holds the occluder in the deployed, expanded profile configuration is provided within a delivery sheath. The proximal end of the catch member includes a flap that when positioned proximal to the proximal end of the occluder holds the occluder in the expanded profile configuration. The flap is sized and formed of a material that allows the flap to deform by bending back and forth in axial and radial directions. In certain embodiments, the flap has segments divided by notches. In certain embodiments, deforming the flap in the proximal direction requires a different amount of force than deforming the flap in the distal direction.
US08814945B2 Implantable wrist joint assembly with spherical inter-support
A multi-component wrist joint assembly incorporated into reconditioned end surfaces established between an upper radius bone and at least opposing lower scaphoid and lunate bones. A first component is anchored into the upper radius reconditioned end surface and exhibiting a first exposed support surface. A second component is anchored into the lower scaphoid and lunate reconditioned end surfaces and exhibiting a second exposed support surface. A spherical shaped intermediate component is supported in at least one of eccentric or rotational fashion between the first and second anchored components.
US08814944B2 Tibial implant base
An orthopedic prosthesis includes a tibial implant and a tibial insert. The tibial implant includes an upper surface, a medial side, a lateral side and a first locking structure provided on the upper surface where the medial side and the lateral side of the tibial implant are defined by a medial-lateral midline. The tibial insert includes a second locking structure provided on its bottom surface. The first and second locking structures are configured for engaging each other along an engagement direction vector when the tibial insert is inserted into the tibial base towards the posterior side. The engagement direction vector is angled away from the medial-lateral midline of the tibial implant towards the medial side of the tibial implant by a predetermine angle.
US08814942B2 Bone graft applicator
A method for applying bone graft to an orthopaedic implant. The method includes using a bone graft applicator including a pair of arms, a bone graft receptacle coupled to the arms, and a linking mechanism coupled to the bone graft receptacle. The linking mechanism is slid over a portion of the orthopaedic implant. Bone graft is scraped into the bone graft receptacle. The user closes the bone graft receptacle over the portion of the orthopaedic implant and then removes one of the bone graft applicator and the orthopaedic implant from the other of the bone graft applicator and the orthopaedic implant.
US08814940B2 Systems and methods for spinal fusion
A system and method for spinal fusion comprising a spinal fusion implant of non-bone construction releasably coupled to an insertion instrument dimensioned to introduce the spinal fusion implant into any of a variety of spinal target sites.
US08814933B2 Foldable intravascularly inserted blood pump
A foldable intravascularly insertable blood pump employs an impeller with radially delivering vanes in combination with an annular deflection channel. The impeller is driven by a shaft extending through a catheter wherein the impeller and its envelope are foldable by relative displacement of the shaft and catheter.
US08814931B2 Staged deployment devices and methods for transcatheter heart valve delivery systems
A delivery device for a collapsible heart valve includes an operating handle, including a frame defining a movement space therein, a carriage assembly moveable within the movement space, and a first resheathing lock having a locked position and an unlocked position. The delivery device further includes a catheter assembly, including a first shaft around which a valve-receiving compartment is defined, the first shaft being fixedly connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly. The distal sheath is moveable between a closed condition adapted to maintain the valve in the compartment and an open condition adapted to fully deploy the valve. With the resheathing lock in the locked position, the distal sheath is unable to move to the open condition to fully deploy the valve.
US08814927B2 Partially biodegradable stent
A partially biodegradable stent includes a main net body of hollow cylindrical shape formed of elastically deformable wires interlaced with each other, the net body extending in a longitudinal direction and terminating at open opposite ends, and an auxiliary net portion provided at one of the open opposite ends of the main net body, the auxiliary net portion formed of a biodegradable wire which can be degraded and removed by a bodily fluid. The auxiliary net portion is formed by interlacing the biodegradable wire into a cylindrical shape independently of the main net body or by interlacing the biodegradable wire with the elastically deformable wires at one of the open opposite ends of the main net body.
US08814926B2 Methods and apparatus for stenting comprising enhanced embolic protection coupled with improved protections against restenosis and thrombus formation
Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
US08814923B2 Light dispensing apparatus
There is provided an apparatus, a method and a computer program. The apparatus comprises medical imaging unit for generating a group of voxel values of a patient, a voxel value representing an electromagnetically detectable functional state in a brain voxel of the patient, data processing unit for generating from the group of voxel values of the patient an indication that represents a level of a specific medical disorder of the patient, and illumination unit for directing non-invasively a dose of light to the brain of the patient.
US08814922B2 Method for treatment of fingernail and toenail microbial infections using infrared laser heating and low pressure
A method of treating microbial infections, which consists of the steps of sequentially and repeatedly irradiating the microbe with continuous or pulsed infrared radiation and continuous or pulsed cooling such that heat and cold alternatively penetrates to the site of the infection in order to inactivate the pathogen.
US08814921B2 Tissue ablation and cautery with optical energy carried in fluid stream
Methods and systems for modifying tissue use a pressurized fluid stream carrying coherent light energy. The methods and systems may be used for resecting and debulking soft and hard biological tissues. The coherent light is focused within a stream of fluid to deliver energy to the tissue to be treated.
US08814916B2 Method and apparatus for minimally invasive subcutaneous treatment of humerus fractures
The instant invention is a novel method and construct for temporary or definitive minimally invasive treatment of a broken humerus. The method includes the steps of tunneling an elongated plate subcutaneously in the subcutaneous fat layer substantially parallel to the fractured humerus; and attaching the ends of the elongated plate to the fractured humerus. The elongated plate remains disposed in the subcutaneous fat layer and away from, but parallel to the humerus once attached to the humerus.
US08814911B2 Polyaxial bone screw with cam connection and lock and release insert
A polyaxial bone screw assembly includes a threaded shank body having an integral upper portion receivable in a receiver, the receiver having an upper channel for receiving a longitudinal connecting member and a lower cavity cooperating with a lower opening. A retaining member for capturing the shank in the receiver includes a sloping surface for a frictional, press fit, cammed engagement with the shank. A compression insert having a resilient structure provides non-floppy positioning of the shank with respect to the receiver and also independent locking of the shank with respect to the receiver.
US08814909B2 Modular multi-level spine stabilization system and method
A multi-level spine stabilization system is formed by providing a plurality of securing members, providing a plurality of rod segments configured to extend between the plurality of securing members, selecting a first rod segment from the plurality of rod segments based upon a first distance between a first vertebra and an adjacent second vertebra, selecting a second rod segment from the plurality of rod segments based upon a second distance between the second vertebra and an adjacent third vertebra, attaching a first, a second, and a third of the plurality of securing members to the first, the second, and the third vertebrae, respectively, forming a rod using the first and second rod segment, and attaching the rod to the first, the second, and the third securing members.
US08814908B2 Injectable flexible interspinous process device system
An injectable, flexible interspinous process device and a delivery system. The interspinous process device is flexible and can be fillable in situ with a desired amount of biocompatible material. The interspinous process device has a container portion. A support element, such as a self-expanding mesh, is used in conjunction with the container to provide added structural support. The mesh also facilitates deployment of the device when it is properly positioned. A conduit may be coupled to the interspinous process to fill the device. A delivery system is also provided for delivering the flexible interspinous process device to the desired location. The delivery system includes an outer catheter that is disposed over the interspinous process device to maintain it in the undeployed state and thus facilitate delivery of the device to the desired location. An inner removable sleeve and a guidewire may also be used with the delivery system.
US08814905B2 Surgical filament snare assemblies
A surgical filament snare assembly including an anchor capable of being fixated in bone and having a filament engagement feature. A first filament has a noose on a first portion of at least a first limb and has a second portion connected to the filament engagement feature of the anchor. Preferably, at least one free filament limb, which in some embodiments is a length of the first filament and in other embodiments is a second filament, is capable of being passed through tissue to be repaired and has at least one end passable through the noose to enable incremental tensioning of the tissue after the anchor is fixated in bone. The noose strangulates the free filament limb when tension is applied to at least one of the free filament limb and the noose.
US08814898B2 Methods and devices for deploying and releasing a temporary implant within the body
Methods, devices and systems for delivering a device assembly into a gastric or other space within the body, allowing the device to expand to occupy volume within the gastric space and, after an effective period of time, delivering a substance or stimulus to begin breakdown of the expanded device so that it may release from the body.
US08814897B1 Contagion prevention systems
Contagion prevention systems used in oral examinations.
US08814883B2 Minimally invasive surgical stabilization devices and methods
The various embodiments of the present inventions provide stabilization devices and methods for use of the stabilization devices with minimally invasive gynecological procedures such as methods of preventing pregnancy by inserting intrafallopian contraceptive devices into the fallopian tubes.
US08814877B2 Use of micro- and miniature position sensing devices for use in TKA and THA
A system for assisting in a surgical process, comprising: (a) a surgical device taken from a group consisting of a surgical tool and a surgical implant; (b) a positional sensor carried by the surgical device, the positional sensor including a wireless transmitter and associated circuitry for transmitting sensor data from the transmitter; and (c) a computer system including a wireless receiver and signal conditioning circuitry and hardware for converting sensor data received by the wireless receiver into at least one of (i) audio feedback of positional information for the surgical device and (ii) visual feedback of positional information for the surgical device.
US08814874B2 Navigated cut guide for total knee reconstruction
A method and apparatus are disclosed that provides a system to perform a procedure on a patient or on a patient's anatomy. The apparatus can include a guide member that includes at least three degrees of freedom of movement of a guide or alignment portion. The apparatus can be used to guide or form reference points for a guide to resect a portion of an anatomy.
US08814871B2 Surgical tools with extendible and rotatable accessory components
Surgical tools are disclosed for minimally-invasive planing of bone surfaces that will support prosthetic implants, such as cartilage-repair implants. Such planing tools must create smooth surfaces that will closely fit the anchoring surface of an implant. Such tools can use a rotating cylindrical burr, partially covered by a cowl having adjustable components to control grinding depth and bone curvature. Burrs can be mounted on the ends of rotating shafts, or they can be angled, using drive-coupling interfaces. In other embodiments, shaver or burr tools can be supplemented by accessory-type devices (such as suction tubes, cautery tips, and pinchers) that can be extended beyond the normal working tip of a tool, to enable additional functions that will be useful during surgery.
US08814870B2 Hook shaped ultrasonic cutting blade
An ultrasonic surgical blade has a blade body and a shank. The shank is fixed at one end to the blade body and is operatively connectable at an opposite end to a source of ultrasonic vibrations. The shank has a longitudinal axis. The blade body is eccentrically disposed relative to the axis.
US08814868B2 Instrumented orthopaedic implant for identifying a landmark
A system (110, 150) for targeting a landmark (114, 160) is disclosed. The system includes an instrumented medical implant (112, 152), a control circuit (118, 153), a power supply (120, 157), and a landmark identifier (122, 154). The instrumented medical implant (112, 152) has one or more landmarks (114, 160) and each landmark (114, 160) has a corresponding coil (116, 162). The control circuit (118, 153) is electrically connected to the corresponding coil (116, 162), and the power supply (120, 157) is electrically connected to the control circuit (118,153). The landmark identifier (122, 154) has a magnetic sensor (124, 155) for sensing the corresponding coil (116, 162).
US08814866B2 Method for minimally invasive treatment of unstable pelvic ring injuries
The instant invention is a novel method for construct for temporary or definitive pelvic stabilization. The method uses the already established principles of anterior external fixation combined with internal hardware placed in a minimally invasive fashion. Fixation means are affixed to the ilia and both a rigid, subcutaneous anteriorly bowed elongated plate and a subcutaneous posterior plate are connected between the fixation means.
US08814861B2 Electrosurgical electrode and method of manufacturing same
An electrosurgical device coated an epoxy modified rigid silicone powder coating which includes a solvent-free hydroxyl functional solid phenyl silicone resin in the range of about 40% to about 60% parts per weight of the coating; a calcium metasilicate in the range of about 20% to about 40% parts per weight of the coating; an epoxy cresol novalac resin in the range of about 5% to about 15% parts per weight of the coating; an ultra-fine air micronized muscovite mica in the range of about 0% to about 10% parts per weight of the coating; a 60% active powder version of a methyl alkyl polysiloxane in the range of about 3% to about 7% parts per weight of the coating; a high temperature calcination of coprecipitated compound with manganese-copper-iron in the range of about 0% to about 10% parts per weight of the coating; an o-cresol novolac resin in the range of about 0.5% to about 3% parts per weight of the coating; and an acrylate copolymer in the range of about 0.5% to about 3% parts per weight of the coating. This coating is applied to the surfaces of an electrosurgical device minimize the build-up of charred tissue (i.e., eschar) on the surfaces of the electrosurgical device.
US08814856B2 Extension and retraction mechanism for a hand-held device
The disclosure describes a hand-held device that utilizes a mechanical lever system to operate the device with a single hand. The mechanical lever system is coupled to a sliding element within the housing of the hand-held device that slides linearly. The sliding element may be attached to another element that is extended, retracted, or rotated in or out of the device. For example, the hand-held device may be used for prostate ablation therapy. The hand-held device may include an ablation needle electrode that is extended out of a catheter and into a tissue of a patient by depressing an extension lever of the mechanical lever system to deliver ablation therapy. Depressing a retraction lever of the mechanical lever system may retract the needle electrode back into the catheter of the hand-held device. Other variations of the mechanical system and applications of the hand-held device are also described.
US08814851B2 Thermal ablation system
A thermal ablation system comprises a fluid handling unit receiving fluid from a fluid source at a first pressure, the fluid handling unit including a heater heating the fluid to a desired temperature and a pump and an introducer including a sheath which, when in an operative position, is received within a hollow organ, the sheath including a delivery lumen introducing fluid heated by the heater to the hollow organ and a return lumen withdrawing fluid from the hollow organ and returning the withdrawn fluid to the console via a return lumen, wherein the pump increases a pressure of the fluid between the fluid source and the delivery lumen of the introducer.
US08814845B2 Delivery of biological compounds to ischemic and/or infarcted tissue
The delivery of biological compounds to ischemic and/or infarcted tissue are described herein where such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for performing any number of procedures on the tissue for identifying, locating, and/or accessing ischemic and/or infarcted tissue.
US08814844B2 Absorbent article
Disclosed is an absorbent product wherein a pair of folded portions that can be folded back is formed on both sides in the width direction of the absorbent product on portions of a flap. On the pair of folded portions, latch members that can fasten to prescribed areas of a front waistline member or a rear waistline member are respectively disposed. The flap is connected to the front waistline member or the rear waistline member at the two ends in the width direction of the absorbent product. Between the two ends and the folded portions, non-connected regions are provided where the flap is not connected to the front waistline member or the rear waistline member.
US08814838B2 Respiratory secretion retention device, system and method
A novel and non-obvious apparatus, system, and method for managing respiratory secretions and fluids in sections of artificial airways. In an embodiment of the invention, a respiratory secretion retention (RSR) device configured to connect to an artificial airway can be provided. The respiratory secretion retention (RSR) device can include a housing that defines a passageway for the flow of respiratory gases, a chamber that is defined by the housing, where a portion of the chamber is configured to retain exhaled respiratory particulate and liquid, and at least one element configured to provide for repositioning at least a portion of the housing with respect to the artificial airway. In an aspect of this embodiment, the at least a portion of the housing can be repositioned with respect to the artificial airway without opening the artificial airway to the atmosphere.
US08814836B2 Devices, systems and methods for treating the skin using time-release substances
According to some embodiments, a microdermabrasion device for treating skin comprises a handpiece assembly having a distal end and a proximal end. The handpiece assembly includes at least one delivery conduit and at least one waste conduit. The microdermabrasion device additionally comprises a tip configured to be positioned along the distal end of the handpiece assembly, wherein the tip is adapted to contact skin surface. In several embodiments, the tip comprises a lip, a first opening in fluid communication with the fluid delivery conduit and a second opening in fluid communication with the waste conduit. In one embodiment, the device includes one or more abrasive elements positioned along a distal end of the tip, wherein the abrasive elements are configured to selectively remove skin as the tip is moved relative to a skin surface. In some embodiments, the delivery conduit is configured to selectively deliver at least one time-release material to the skin surface being treated.
US08814827B2 Retractable syringe
A syringe including a barrel, a needle subassembly holder positioned in the barrel, and a needle subassembly positioned in the holder. The needle subassembly includes a needle hub releasably connected to the holder and a needle connected to the hub. Further, the syringe includes a piston slidably received by the barrel. The piston includes a piston body and a piston head having a releasable portion temporarily covering a hatchway. The piston also includes a valve positioned proximal of the hatchway and movable between blocking and passing positions. A user may push the piston distally beyond an injected position in which the piston head contacts the holder causing the holder to move distally and the hub to contact the barrel, causing the barrel to bow, thereby storing potential energy. When the potential energy reaches a threshold amount sufficient to overcome forces holding the hub in the holder, the barrel rebounds toward its un-bowed shape thereby propelling the needle hub and needle proximally past the releasable portion and the valve and into the piston body. The valve then automatically returns to the blocking position thereby ensuring that the needle subassembly does not move proximally out of the piston body.
US08814824B2 Steerable short sheath access device
The present invention relates to steerable access sheath assembly (12). Moreover, the present invention relates to a steerable short sheath access device (10) for use in epicardial procedures. Embodiments of the present invention including shorter steerable access sheaths or introducers (10, 12) may provide epicardial access for various ablation tools and devices for the performance of various ablation procedures or procedures involving alternate energy sources. The steerable access device (10) provides an elongated member (20) having a proximal section (26) and a distal section (28), wherein the deflection of the distal section (28) provides a primary curve including an inner radius (r1) that result in a secondary curve of proximal section (26) having an inner radius (r2, r3), wherein the inner radius of curvature (r1) of the primary curve is less than the inside radius of curvature (r2, r3) of the secondary curve.
US08814822B2 Reciprocating delivery of fluids to the body with analyte concentration monitoring
A volume of an analyte-enriched fluid can be withdrawn out of a user's subcutaneous compartment using a patch unit that includes a reversible pumping mechanism. The volume can be withdrawn out of the body and into the patch unit through a cannula inserted into the subcutaneous compartment so that an analyte concentration in the volume can be measured using a sensing element within the patch unit. After analyte concentration analysis, at least the volume can be delivered back into the subcutaneous compartment by operating the pumping mechanism in a forward direction. biologically compatible fluid can optionally be pumped into the subcutaneous compartment from a reservoir in the patch unit and then allowed to partially or completely equilibrate with the analyte concentration in the interstitial fluid of the subcutaneous compartment via a permeable or semi-permeable cannula surface before being drawn back into the patch unit for analysis. Related systems, apparatus, methods, and/or articles are also described.
US08814817B2 Ankle protector
An ankle protector comprises an elastic webbing element, formed with a tubular construction thereby to surround and embrace a user's ankle region. The webbing element is defined by upper and lower apertures to enable a user's foot to pass therethrough when putting the ankle protector on. Each of said upper and lower apertures is formed by overlock-stitching an edge of the elastic webbing material, such that said apertures have no perceptible ribs. A cushioning element is attached to the webbing element (11) and is adapted to cover and protect a user's Achilles tendon. The cushioning element protrudes inwardly relative to the circumference of the tubular webbing element.
US08814813B2 Cranial device with rotary tilt sensor
The invention relates to an improved cranial device with a rotary inclination detector, including a container box which can be secured to the cranium of sleeping person and which contains an electric motor and an eccentric counterweight coupled thereto, forming a vibrator. The device also includes a battery or a battery holder for at least one battery, which is provided with two axially opposed projecting contacts or studs. The container box is provided with inclined formations with dielectric properties, on which the battery or battery holder can roll by means of the studs thereof, and two electric contacts on which the inclined formations terminate, such that, when the battery holder is placed on the electric contacts, the motor circuit is closed, thereby activating the vibrator.
US08814812B2 Reciprocating brace
An apparatus for passive contraction of at least one finger of a patient with an upper arm unit, a lower arm unit, and at least one connective line. The apparatus is configured such that elbow extension of the patient promotes finger flexion. This is accomplished by taking advantage of the geometry of the arm, where the distance from a point on the patient's humeral area to the patient's fingers is greater when the patient's arm is in extension than when it is in flexion. In one aspect, the upper arm unit is configured to connect to a portion of the patient's arm between the patient's elbow and shoulder and the lower arm unit is configured to connect to a portion of the patient's arm intermediate the patient's hand and elbow.
US08814808B2 Body fluid sampling device
Body fluid sampling device comprising a skin-piercing element having a collection zone for receiving body fluid. In one embodiment, the collection zone includes a plurality of holes, e.g., 3 or more holes, or 50 to 100 holes. The hole size may be small, e.g., having a diameter of 0.01 to 0.5 mm. The holes may or may not extend through the lancet. In some embodiments, the holes have a depth of 50 to 500 μm. In other embodiments, the collection zone is porous, or is a roughened area. The collection zone can take up a very small volume of body fluid, e.g., 3 to 10 nL, in a very short time period, e.g., less than 0.5 seconds. In other embodiments, the device further comprises a fluid receiving means spaced apart from the collection zone so that body fluid in the collection zone will not contact the fluid receiving means initially.
US08814807B2 Spinal canal access and probe positioning, devices and methods
Methods and devices for detecting positioning of a probe in a tissue of a patient. A method can include providing a detection device; advancing a device coupled probe through the tissue of the patient and toward the patient's spinal canal; detecting a change in pressure about the distal portion of the coupled probe during advancing, where the detected pressure change indicates probe positioning in the patient's spinal canal; outputting the detected pressure change or indication of probe positioning to a visual display.
US08814806B2 Device for determining a condition of flow in a respiration system
A device for detecting the condition of flow in a respiration system combines the function of a nonreturn valve with the function of flow measurement in a common device. The device includes a valve arrangement (1) with a valve disk (9) and with a valve body (8), wherein the position of a valve disk (9) in relation to a valve seat (11) is detected. An indicator for a flow and a direction of flow (5), (6) is determined from the position of the valve disk (9). The position of the valve disk (9) can be determined inductively, electrically, electromechanically or optically. The flow and direction of flow (5), (6) determined can be used to control the respiration in a medical device.
US08814805B2 Complex signal demodulation and angular demodulation for non-contact vital sign detection
Methods for recovering a detected signal in non-contact vital sign detection are provided. According to one embodiment, a detected reflected signal from a non-contact vital sign detection system can be received and provided along I channel and Q channel signal lines. A complex signal S(t) can then be reconstructed from the I channel and Q channel signal lines through complex signal demodulation. A Fourier transform can be used to obtain the detected signal's spectrum for spectrum analysis. Angular demodulation can be used to recover the information corresponding to original body movement. The complex signal demodulation and angular demodulation techniques used to provide information to determine original body movement are capable of avoiding the null detection point without limitations on frequency tuning or channel selection.
US08814804B2 Interactive blood-alcohol content tester
A blood-alcohol content (BAC) tester for use at a facility serving alcohol. The BAC tester includes a breath-sampling unit having an air-chamber unit defining a closed position and an open position. The air-chamber unit has a first air-chamber block and a second air-chamber block, the first air-chamber block and the second air-chamber block defining an air chamber for receiving air exhaled from a user. The breath-sampling unit also includes a drive unit coupled to the second air-chamber block and an alcohol sensor. The BAC tester also includes a sensor circuit communicatively coupled to the drive unit and the alcohol sensor. The sensor circuit is configured to cause the drive unit to move the second-air chamber block relative to the first air-chamber block so as to cause the air-chamber unit to be in the closed or the open position.
US08814800B2 Apparatus and method for enhancing and analyzing signals from a continuous non-invasive blood pressure device
A system and method of enhancing a blood pressure signal is disclosed. The volume of an artery in a finger is measured by a photo-plesthysmographic (PPG) system, which produces a PPG signal. This PPG system is placed inside a cuff, and the cuff pressure is controlled by the PPG signal. The portion or component of the PPG signal having a frequency higher than a predefined threshold frequency is then modified or enhanced, such as by multiplying the high frequency component by a calibration factor. A blood pressure signal is then calculated using the cuff pressure and the modified PPG signal. A blood pressure contour curve may then be generated, and a variety of parameters may be calculated using the curve.
US08814799B2 Low profile intravascular ultrasound catheter
The present invention provides low profile intravascular ultrasound catheters adapted to access sites within the patient's body through narrow blood vessels, e.g., the radial artery. In an embodiment, a low profile catheter comprises an catheter sheath, a short guidewire receiver attached to the distal end of the catheter sheath, and a telescope assembly at the proximal end. The catheter sheath comprises a main portion and a tapered portion for increased flexibility toward the distal end of the catheter. In one embodiment, a rotatable and translatable imaging core is received within the catheter sheath for ultrasound imaging. A short guidewire receiver is used to allow the imaging core to be advanced farther distally with respect to the distal end of the catheter. In an embodiment, the catheter sheath extends through a portion of the telescope assembly to provide enhanced support of the imaging core within the telescope assembly.
US08814796B2 System and method for tissue ablation in a body cavity
A tissue ablation system and method of forming same includes an ablation device having a substrate with an outer surface and energy transport elements coupled to the outer surface. The substrate is configured to have a shape that approximates an interior shape of a uterus. The system and method further including an energy source electrically coupled to the energy transport elements and at least one ultrasonic transducer positioned in a lateral region of the uterus.
US08814791B2 Systems and methods for monitoring pain management
The present disclosure relates to systems and methods for monitoring pain management using measurements of physiological parameters based on a PPG signal. A reference physiological parameter may be compared against a later measurement to identify a change in condition that may indicate a pain management problem.
US08814786B2 Guiding device for use with laryngoscope
A guiding device for use with a laryngoscope for assisting in the insertion of an endotracheal tube into a patient, the device comprising a guiding means for guiding an endotracheal tube through the patient's upper airways, and an attachment means to attach the guiding means to the blade of the laryngoscope. A laryngoscope comprising the guiding device is also disclosed.
US08814783B2 Illumination lens and endoscope
An illumination lens to be disposed in a front end of a light guide of an endoscope includes an entrance face and an exit face. The entrance face has positive power. The exit face has positive power. The following Expression (1) is satisfied while the following Expression (2) is satisfied. 1.2<1/r1×φ<1.8,  (1) 0.24<1/r2×φ<0.96,  (2) where φ [mm] is a diameter of the lens, r1 [mm] is a curvature radius of the entrance face, and r2 [mm] is a curvature radius of the exit face.
US08814782B2 Solid state variable direction of view endoscope
An endoscope with a wide angle lens that comprises an optical axis that is angularly offset from a longitudinal axis of the endoscope such that the optical axis resides at an angle greater than zero degrees to the longitudinal axis. The wide angle lens system simultaneously gathers an endoscopic image field at least spanning the longitudinal axis and an angle greater than ninety degrees to the longitudinal axis. The endoscope further includes an imager comprising an imaging surface area that receives at least a portion of endoscopic image transmitted by the wide angle lens system and produces output signals corresponding to the endoscopic image field and image forming circuitry that receives the output signal and produces an image signal.
US08814779B2 Stereoscopic endoscope
Two side-by-side optical paths transmit stereoscopic right side and left side images onto the surface of a single image sensing chip. The single image sensing chip may be placed at various orientations with respect to the lens trains in the optical paths. In some embodiments a single prism is used to turn the light for both the right side and left side images onto the single image sensing chip. In other embodiments one prism is used to turn the light for the right side image and another prism is used to turn the light for the left side image, and the reflective surfaces of the two prisms are substantially coplanar such that the right side and left side images are incident on the single image sensor chip.
US08814777B2 Devices for minimally invasive pelvic surgery
The invention, in various embodiments, provides systems, devices, and methods for treating urinary incontinence.
US08814774B2 Radiation treatment method for use with a radiation treatment bra
A method for radiation treatment includes adjusting a plurality of adjustable elements on a radiation treatment bra to establish a reference breast geometry and aligning the patient to a radiation treatment machine by projecting a light field through windows provided in the radiation treatment bra during a radiation treatment planning session. To begin actual radiation treatment, the reference breast geometry is reestablished by repeating the original adjustments of the adjustable elements, as necessary. Alignment is re-established by viewing tattoos through the windows in conjunction with the light field.
US08814771B2 Tool holding and conveying chain
There is provided a tool holding and conveying chain adapted to securely lock and position a tool pot, i.e., a connecting pin, to a pin hole of either an outer or inner link plate so that the tool pot does not to turn and to achieve steady and smooth attachment and removal of a tool in and out of the tool pot with a simple attachment structure. The tool pot has a pair of positioning flat portions formed by cutting a link plate attaching outer circumferential region of the tool pot and the outer link plate has a pair of positioning cooperative flat portions formed so as to bulge out of an inner circumference to a center of a pin hole. The positioning flat portions of the tool pot is fitted into and locked by the positioning cooperative flat portions when the tool pot is attached in the link plate.
US08814770B2 Laser nozzle changing device
A method for processing workpieces with a laser processing machine including a laser processing head having a nozzle receiving member configured to receive a laser nozzle. The method includes holding a workpiece on a workpiece support plane of a workpiece support, transferring a laser nozzle between a nozzle magazine of a nozzle changing device located at a first side of the workpiece support and a nozzle receiving member of the laser processing head located at a second side of the workpiece support such that the laser nozzle is assembled on or disassembled from the nozzle receiving member, and moving the laser nozzle through a through-opening defined in the workpiece support along a transverse direction to the workpiece support.
US08814769B2 Machine tool and tool holder
A machine tool having a turning function and a milling function includes a spindle, a spindle housing supporting the spindle in a rotatable manner, a main clamp provided at the spindle, an auxiliary clamp provided at the spindle housing, and a double arm with a first gripper and a second gripper. The auxiliary clamp clamps a tool holder together with the main clamp during fixing a fixed tool. The double arm exchanges a tool holder grasped at the first gripper for another tool holder grasped at the second gripper by rotating and sliding movements. The auxiliary clamp is arranged at a position not interfering with the double arm that moves during exchanging tool holders. By such a configuration, a machine tool achieving a clamping force sufficient to withstand the load during a turning process, and that allows tool exchange in a short period of time, and a tool holder employed in such a machine tool, can be provided.
US08814767B2 Exercise device and method
An exercise device of the present invention includes a beam; rods removeably affixed and extending from ends of the beam; wheels rotatably mounted on the rods; handles positioned on outer ends of the rods; and a body-part engagement device for engaging a user's hands, feet, or knees with the device. Multiple exercises that exercise various muscle groups of the human body may be performed with the exercise device.
US08814766B2 Skiing exercise apparatus
An apparatus and method for exercising using an apparatus that includes an upper assembly, equipped with pedal platforms or a snowboard attachment, which is pivotally attached to a lower frame assembly. The lower frame assembly includes ski pole attachments that enable a user to maintain balance while using the apparatus. When the user stands on the pedals, elastic members coupled to the lower frame assembly and the upper frame assembly maintain level of the upper assembly while also providing some resistance to lateral movement. As the user shifts weight to simulate downhill skiing, the resistance by the elastic members, and an adjustable brake component, provide strength and core exercises similar to skiing.
US08814765B2 Exercise device and method of use
A hand held exercise device for providing a user with a portable workout. The device may generally comprise a central handle diametrically disposed within and spanning across a ring element having a toroidally shaped inner chamber. Internal bumpers within the inner chamber act to limit the range of motion or travel of at least one mobile element within the inner chamber. Rotational forces imparted by the user upon the handle cause movement of the at least one mobile element that is responded to and countered with user muscle flexion. In this manner, a user may perform a satisfactory workout by continually imparting and then resisting rotation force in alternating clockwise and counterclockwise directions.
US08814759B2 Integrated punching bag system
A punching bag base and punching bag assembly. The base provides multiple areas to store exercise accessories such as weighted dumbbells and weighted ankle weights. In one form, the areas formed in the base to receive weights or related exercise equipment form a shape that is complementary to that of the equipment stored in it. In another form, the base can be of a generally hollow construction to accept ballast to provide additional stability of the base when it is placed on a floor or related support structure. The system may also include an integrated hook placed on the pole that allows the user the ability to hang boxing gloves, towels or other exercise equipment. The system may also include a wheel assembly to facilitate ease of movement.
US08814755B2 Performance information sharing systems and methods
We have disclosed a system for sharing information about a first individual who has engaged or is engaging in a first physical activity. The system may include a first portable performance monitoring system that is capable of being carried with the first individual during the first physical activity. The first portable performance monitoring system may include a first processor configured to determine first performance information for the first individual and a transmitter configured to transmit the first performance information. The system may also include a second portable performance monitoring system that is capable of being carried with a second individual during a second physical activity. The second portable performance monitoring system may include a receiver configured to receive the first performance information and a second processor configured to generate display data based on the first performance information.
US08814746B2 Two-array planetary gear system with flexpins and helical gearing
A planetary gear system (P) includes a sun gear (2), a ring gear (4) a carrier (6) located between the sun and ring gears (2, 4), and planet pinions (8, 10) organized in two arrays and supported on flexpin assemblies (32, 34) in the carrier (6). All of the gearing is helical, with the sun and ring gears (2, 4) having their teeth arranged in at double helix angles (herringbone) and the planet gears (8, 10) at single helix angles. The pinions (8) of the one array engage the teeth of one angle on the sun and ring gears (2, 4) and the pinions (10) of the other array engage the teeth of the other angle on the sun and ring gears (2, 4). Torque transfers through the carrier (6) through two torque paths (a, b)—one to the flexpin assemblies (32) for one array and the other to the flexpin assemblies (34) of the other array—and the paths (a) is stiffer than the path (b). Owing to the helical cut of the teeth the planet pinions (8, 10) of the two arrays exert oppositely directed axial forces (A) on the sun gear (2). The sun gear (2) is free to shift axially or float with respect to the planet pinions (8, 10) of the two arrays, so the axial forces (A) imparted to the sun gear, while opposite, are equal. Hence, the tangential forces (T), which transfer the torque, are likewise equal, notwithstanding the difference in flexibility of the two torque paths (a, b). Even though the carrier (6) may undergo different deflections at the flexpin assemblies (32, 34) for the two arrays of planet pinions (8, 10), the planet pinions (8, 10) of the two arrays transfer torques of equal magnitude.
US08814743B2 Synchronizing disconnect device
A transmission includes an input member, an output member, a set of four planetary gear sets each having first, second, and third members, a plurality of torque transmitting mechanisms each selectively engageable to interconnect at least one of the first, second, and third members with at least one other of the first, second, third members and a stationary member, and a synchronizer assembly that selectively connects and disconnects one member of one of the planetary gear sets.
US08814740B2 Two-speed power take-off unit with mode clutch
A two-speed power take-off unit adapted for installation in an all-wheel drive vehicle having a transversely mounted engine/transaxle powertrain. The two-speed power take-off unit includes a planetary gear reduction unit capable of establishing a high-range and a low-range drive connection between the powertrain and a transfer assembly. The transfer assembly provides drive torque to a front differential assembly driving the front wheels and a PTU gearset driving the rear wheels.
US08814737B2 Wheel driving device
A wheel driving device includes: a reduction mechanism of which at least a part is disposed on an inside of a wheel; a casing; a relative rotation member rotating relative to the casing; a bearing disposed between the casing and the relative rotation member; and an oil seal sealing a space where the reduction mechanism is present, wherein an outer race of the bearing includes a main body portion of which an outer periphery is disposed on an inside of the casing, and an extending portion which extends from the main body portion in an axial direction and of which an outer periphery is exposed from the casing, and the oil seal abuts on the extending portion and the relative rotation member.
US08814735B2 Metal V-belt of continuously variable transmission
Each steel element for a V-belt of a continuously variable transmission has a flank (4a) that comprises a plurality of equally spaced raised portions (41) each being placed between two fine grooves (42). A flat flatness ratio (FR) given by the equation (1) is set to the highest one of values that are capable of practically machining the flank (4a) of the steel element (4) and capable of causing the flank (4a) to exhibit a given and satisfied lubrication oil discharging effect, and a groove pitch (GP) that is a distance between the two fine grooves (42) is set to a value that is capable of practically machining the flank of the steel element and capable of causing the flank to exhibit a given and satisfied lubrication oil discharging effect. The groove pitch thus set is a value that is permitted by the higher value of the flatness ratio thus set. FR (%)=WRP/(WRP+WG)×100  (1) wherein: FR: Flatness ratio WRP: Width of the raised portion (41) WG: Width of the groove (42).
US08814733B2 Baseball or softball bat with modified restitution characteristics
A softball or baseball bat with modified restitution characteristics is provided. The bat can comprise a substantially rigid shell coupled with a single or multi-piece insert. The shell can comprise a tip end, a barrel, a handle taper, and a handle. The insert can be press-fit or adhered to the inside of the barrel of the shell. The insert can be a single or multi-piece design and can be single or multi-layered. The insert can comprise a material capable of impact absorption. Portions of the insert can be separated from the shell with a separation layer to improve restitution in certain areas of the bat. The insert can also comprise multiple layers that are separated from each other with a separation layer to improve restitution in certain areas of the bat. The material and thickness of the insert and the shell can be varied to meet applicable restitution requirements.
US08814729B2 Tackle practice apparatus and a method for practising tackling in a contact sport
Tackle practice apparatus (1) comprises an inflatable dummy element (3) in the shape of a person, and is releasably coupled to an inflatable ground engaging sled (4) from which a rope (5) extends to a harness (6) which is releasably coupleable to a person for pulling the tackle practice apparatus across a playing pitch for tackle practice by a player. The dummy element (3) comprises a base element (9) and an inflatable central bladder (7) extending upwardly from the base element (9). Two inflatable lower peripheral bladders (10) and two inflatable upper peripheral bladders (13) extend around the central bladder (7). The lower peripheral bladders (10) are located below a waist high position (14). The base element (9) comprises an inflatable first base bladder (15) which is inflatable with water to provide ballast to the dummy element (3), and an inflatable second base bladder (16) above the first base bladder (15) from which the central bladder (7) extends. On the dummy element (3) being correctly tackled below the waist high position (14) by a player, air from the central bladder (7) is expelled through a whistle (31), thus indicating a correct tackle. The sled (4) comprises an inflatable ring (21).
US08814728B2 Training and coordination device
A training and coordination device including a projectile member such as a ball or sack secured to an elastic string is described. The first end of the elastic string is attached to a location and the second end is connected to the projectile member. At least an end portion of the elastic string secure to the projectile member comprises multiple strands of an odd number. The multiple strands of the elastic string in conjunction with the elasticity of the string generate a random motion of the sack when the sack moves relative to the string.
US08814723B2 Rotational molded golf club heads
Wood-type golf clubs and/or golf club heads include: (a) a golf club head base member including a face member having a ball striking face; and (b) a polymeric body member engaged with the golf club head base member, wherein the polymeric body member is formed via a rotational molding process (or other centrifugal force inducing molding process) and/or engaged with the golf club head base member via a rotational molding process (or other centrifugal force inducing molding process). The polymeric body member forms at least a portion of a crown member of the club head in some structures.
US08814721B2 Method for making a golf club face
An improved face for a golf club head includes shallow and deep markings configured to provide a pleasing appearance when viewed head on, and to frame the central region of the impact surface of the face when viewed at address. Use of only shallow markings in the central region of the impact surface prevents existence of stress fractures resulting from use of deep markings in the central region. This allows for a face thinner than those incorporating conventional grooves in the central regions of their impact surfaces, resulting in both superior resistance to cracking and improved C.O.R. Specified methods of manufacture are particularly suited for making clubs incorporating these shallow and deep markings.
US08814720B2 Golf club heads with grooves and methods of manufacture
Embodiments of golf clubs, golf club heads, and methods of manufacture are described herein. In one embodiment, a golf club head includes a strike face having one or more grooves with edges, where one or more of the edges is unsmooth. Other embodiments are also described herein.
US08814716B2 Golf practice device
A golf practice device having a simulated putting green surface having artificial turf that is approximately the same height and an appearance similar to an actual grass putting surface. Surrounding the putting surface is a collar of artificial turf with grass blades that are longer than the putting surface portion. The turf surfaces may have the ability to float or a floatable substrate can be disposed below the turf for using the device as a floating target for golf shots.
US08814709B2 Intermodulation-resistant flexible shaft having electrically insulating coated wires
A flexible shaft for torque transfer has a plurality of metal wires that are helically wound in a plurality of layers with an opposite winding direction that alternates from layer to layer. Each of the metal wires is surrounded by an electrically insulating insulation layer. The insulating layer prevents a metal-on-metal contact between adjacent metal wires and thereby prevents unwanted intermodulation products.
US08814708B2 Torque limiter and power transmission device
A torque limiter mounted on a hybrid vehicle includes an output plate, an input plate including a first region facing a first main surface of the output plate and a second region facing a second main surface of the output plate, a friction member provided on the first main surface of the output plate and disposed between the first main surface and the first region, and a biasing member being in contact with the second main surface of the input plate, for biasing the output plate toward the first region.
US08814706B2 Radio candle mount
An electronic gaming machine including a candle mount for securing a candle device to the gaming machine and providing wireless communication capabilities to the gaming machine is described. The candle device can include a number of stages that when activated alone or in combination with other stages convey information about the status of the gaming machine. A gaming machine with an existing candle device can be retrofitted with a candle mount that includes a wireless radio device that is operably coupled to the gaming machine.
US08814705B2 Game control device and storage medium including creating and arranging a character
An event starting unit starts an event which associates characters of first and second players. An event managing unit repeatedly executes alternately a first interaction including transmission of first question information to a communication terminal and reception of first answer information from the communication terminal, and a second interaction including transmission of second question information to the communication terminal and reception of second answer information from the communication terminal. A character creating unit creates a new character based on parameters of the characters of the first and second players when the number of times of the first and second interactions reaches a predetermined value. The new character created by the character creating unit is arranged in the first and second virtual spaces.
US08814703B2 Cross-promotion API
A system and computer-implemented method for promoting an electronic game of electronic games is provided. A user interface module is configured to receive an input from a user relating to playing a first and second electronic game. A processor-implemented association engine, operatively coupled to the user interface, is configured to associate user attributes of the first and second electronic games to the user based on the input. An application programming interface (API) is configured to associate a user attribute of a third electronic game different from the first and second electronic games, the API configured to associate based, at least in part, on rule engine implemented by the API and at least one of the user attributes of the first and second electronic games and game data of the third electronic game.
US08814700B2 Methods and systems for presenting pari-mutuel betting options and constructing wagers
Methods and systems of pari-mutuel wagering are disclosed to facilitate the wager construction process. Methods and systems of pari-mutuel wagering may enable an organization to set rules to display the gaming activity. Methods and systems of pari-mutuel wagering may enable players to make subscription as well as programmed bets.
US08814695B2 Amusement devices including simulated court games or athletic events
Some embodiments include a fantasy sports game. In some embodiments, an expected performance value may be determined. In some embodiments, a same player may appear multiple times in a team. Various other embodiments are described.
US08814694B2 Methods and apparatuses for displaying interactive content through a device
In one embodiment, the methods and apparatuses detect a device; detect a status level corresponding to the device; receive content on the device based on the status level; and display the content on the device based on the status level.
US08814690B2 Game machine having data management ability
A game machine (10) includes a card interface (11) configured so that a magnetic card (20) is detachably attached thereto, an element (12) to record a card ID generated on the basis of time information specifying the date and time when the magnetic card (20) is attached to the card interface (11) in a magnetic data recording area (22) provided in the magnetic card (20), and an element (14) to print an access code uniquely obtained by the calculation of a predetermined function based on the card ID in a printing area (21) of the magnetic card (20).
US08814689B2 Method and/or system for mobile interactive gaming
The subject matter disclosed herein relates to systems for providing an interactive experience to game participants.
US08814687B1 Multi-player music game
A video game allows dynamic transitions in the number of players. A player may join other players already playing the game without interrupting the play of the existing players, and a player may cease playing the game without interrupting the play of players who continue playing. The video game uses a method including providing game play for at least one game player including displaying video information based on game program instructions and inputs from a controller. The method also includes determining whether a further player is joining the video game, and if the further player is joining the video game, displaying player specific information associated with the further player to the video information. The method also includes determining whether a player is quitting the video game, and if the player is quitting the video game, removing display of the player specific information associated with the player.
US08814681B2 Candle device for generating display interfaces on the main display of a gaming machine
A candle device for a gaming machine including a secondary processor is described. The candle device can include a number of stages that when activated convey information about the status of the gaming machine. The secondary processor, disposed within a secure enclosure in the candle device, can be configured to control peripheral devices disposed with a main cabinet of the gaming machine that receive control commands from a game controller. In particular, the secondary processor can be configured to determine a size and a position of windows on the main touch screen display where a first window is for outputting video content from the game controller and a second window is for outputting video content from the secondary processor. The secondary processor can use the second window to add new features to the gaming machine, such as a verification interface for transactions involving mobile devices.
US08814680B2 Controller device and controller system
An example device includes a generally plate-shaped housing, a display provided on the front side of the housing, analog sticks, an L button, and an R button. The analog sticks are provided respectively in left and right portions of the display above the center of the housing. The L button and the R button are provided on the back side of the housing so as to generally correspond to the analog sticks on the front side of the housing.
US08814678B2 Apparatus and method for gyro-controlled gaming viewpoint with auto-centering
An apparatus and method is provided for gyro-controlled gaming viewpoint with auto-centering. A virtual camera is positioned at a first position while the virtual camera views a first object at a first direction. Once the system moves, the virtual camera moves to a second position based on a measurement by an angular velocity sensor. While the virtual camera moves to the second position, the viewing direction of the virtual camera simultaneously so as to keep the first object positioned in a same position of a viewing direction of the virtual camera. The apparatus and method allow the system to move a virtual camera based on a measurement of a gyroscope while keeping an object of importance in the center of the field-of-view of the virtual camera.
US08814677B2 Using real-time constructive solid geometry to provide painting and thinning game mechanics
Techniques are described for providing a painting and thinning mechanic within a computer-generated environment (e.g., in a video game). The painting and thinning mechanic allows geometry within the computer-generated environment to be “painted” or “thinned.” Painting and thinning refers to a mechanic that involves making parts of the virtual environment visibly and collidably transparent (thinning) or visibly and collidably opaque (painting). The painting/thinning mechanic may be achieved using binary space partitioning (BSP) trees.
US08814671B2 Access control for electronic entertainment systems including health metrics and physical activity
Systems and methods are provided for controlling the use of electronic systems based upon monitored physical activity. The method can be implemented in a computer infrastructure having computer executable code tangibly embodied on a computer readable storage medium having programming instructions. The program instructions are operable to: provision rules associated with a user and at least one of health metrics and physical activity of the user; monitor the at least one health metrics and physical activity of the user over a predetermined time; and manage access to any of a plurality of electronic systems based on the monitored at least one health metrics and physical activity being in compliance or non-compliance with the provisioned rules.
US08814670B2 System and method for playing a multiplayer game
A system and method for playing a multiplayer game are disclosed. In one embodiment, the method includes, queuing a player for a multiplayer game, determining that at least one criterion for beginning the multiplayer game has not been met, beginning a queuing game for the queued player, and determining that the criterion has been met. In response to determining that the criterion has been met, the method continues by ending the queuing game for the player, determining a queuing game outcome for the player, and beginning the multiplayer game, wherein the multiplayer game is based, at least in part, on the queuing game outcome.
US08814667B2 Wagering game providing a progressive award having an actual value determined by follow-up game play
A gaming system includes an input device for receiving wagers to lay a wagering game in which the player is eligible to win first and second progressive award levels. At least one display device is configured to display a monetary value for the first progressive award level and a number of free spins for the second progressive award level. The gaming system includes two sets of reels, each set being associated with a respective mathematical model. A controller increments the monetary value and the number of free spins based on plays of the wagering game, and awards current values of the monetary value and the number of free spins in response to respective triggering events.
US08814666B2 Apparent skill games for use with predetermined outcomes
A gaming system having a game outcome generator separate from a gaming machine, where the gaming machine is operably connected to the game outcome generator and, upon a game play request from a player, generates a request for a game play result. The game outcome generator generates a specific game outcome (won amount if the game play is a winning result, or a no-win, o-value result) and sends it back to the gaming machine. The gaming machine uses the predetermined result to mimic or simulate a skill based game. The skill based game is designed to play just like an actual skill based game, which may result in poor players not getting the game to a state that has an equivalent value as that which is supposed to be awarded (equal to the predetermined game play). Each game includes a final game event, consistent with the game just played, which enables the game to make up any difference between the actual result of the skill based and the predetermined amount. This preserves the look and feel of the skill based game while allowing the game to award the player the total amount of the predetermined award.
US08814665B2 Gaming system and method for providing a slot driven video story
A gaming system includes a network server connected to a plurality of gaming devices that are adapted to provide a video payout on each play based on a set of payout parameters. Memory at each gaming device stores payout parameters that correspond to each possible gaming result or outcome. When a play is initiated by a player, a gaming result is generated at a gaming device. The gaming device responds by accessing a corresponding payout parameter from the memory which may be a monetary amount, a video presentation segment or a combination thereof. If the payout is video, the network server receives the payout parameter and transmits video presentation segment to the gaming device accordingly. The gaming device then provides a video payout, in the form of displayed video presentation, to the player. The player thus receives at least one form of payment on each play.
US08814661B2 Gaming machines having normal and hot modes
Various embodiments of the present disclosure provide an electronic gaming machine having a default mode in which the electronic gaming machine provides a default average expected payback percentage for each play of a wagering game, and a different second hot mode in which the electronic gaming machine provides an increased average expected payback percentage for each play that wagering game. In The electronic gaming machine is in the default mode for certain periods of play, and is in the hot mode for certain periods of play when, in certain embodiments, a random determination is made that the hot mode will be employed. In various embodiments, players are not informed that the electronic gaming machine is in the hot mode.
US08814659B2 Techniques for generating a random awards using a plurality of average values
A method of providing a game for a gaming device is provided. The method includes providing a plurality of average values. Average values in the plurality of average values represent different values of a prize pool. A wager amount and an input to initiate game play are received. An average value is selected from the plurality of average values and a random award is determined from the prize pool. The random award is determined from the average value selected from the plurality of average values.
US08814657B2 Wagering game with rule set altered prior to completion of reel spin
A gaming machine for playing a wagering game includes a display and a controller. The display displays a plurality of spinning reels that stop to indicate a randomly selected outcome of a plurality of outcomes in response to accepting a wager input from a player. The controller is in communication with the display and is operative to conduct the wagering game in accordance with a basic set of gaming rules. The controller is further operative to cause a modification to a gaming rule of the basic set of gaming rules and to indicate the modification to the player.
US08814654B2 Gaming system, gaming device and method providing trace symbols
The gaming device includes a plurality of mechanical reels which have a plurality of symbols including a plurality of trace symbols. The gaming device includes at least one light source configured to illuminate portions of the mechanical reels when the mechanical reels generate the trace symbols so that for at least one subsequent spin of the mechanical reels, the gaming device can indicate that the mechanical reels generated the trace symbols during a previous spin of the mechanical reels.
US08814647B2 Gaming device and method of operating a gaming device including player controlled targeting
A gaming machine, system, and method including a game event in which a player aims at a target. In one embodiment, the game event includes a plurality of targets. The gaming device displays the plurality of targets to the player and enables the player to select one of the targets. The gaming device designates the player-selected target as the primary target for the game event. Based on the designated primary target, the gaming device identifies one or more of the other targets as secondary targets for the game event. The gaming device determines for each of the primary and secondary targets a probability that that target will be hit in the game event. The gaming device determines which of the targets is actually hit in the game event based on the probabilities associated with the targets.
US08814646B2 Method and apparatus for increasing potential payout opportunities in card games
Systems, apparatuses and methods for increasing potential payout opportunities using multiple card indicia representing multiple cards. One embodiment involves determining whether any one or more of a plurality of cards of a poker game having multiple poker hands are to be randomly provided with multiple card indicia representing multiple cards, presenting the plurality of cards of the poker hands, including the one or more of the plurality of cards determined to be randomly provided with multiple card indicia, and identifying a plurality of resulting hands for each of the multiple poker hands that include a multiple card indicia, where each of the plurality of resulting hands includes a different subset of a total of the indicia of the other cards in the respective poker hand and any cards provided with multiple card indicia.
US08814641B2 System and method for detecting moment of impact and/or strength of a swing based on accelerometer data
An example system and method is provided for detecting a moment of impact and/or strength of a swing based on moving a hand-held device including an accelerometer arrangement. A moment and a magnitude of simulated striking of the object are determined based on one or more accelerometer arrangement outputs resulting from the moving of the hand-held device. Using one or more of aural, visual and tactile outputs, the striking of the object is simulated in accordance with the determined moment of simulated striking and the determined magnitude of the simulated striking.
US08814640B2 Harvesting device and collecting container with improved filling device
A harvesting system includes a self-propelled harvesting machine and a drivable collecting container equipped with a drive unit, which can be positioned relative to the harvesting machine and moved in parallel therewith. Crop is fed directly or indirectly to the collecting container during harvesting operation from the harvesting machine using a feed pipe equipped with an outlet chute. The collecting container is equipped with a device for loading it with crop in a uniform manner. The collecting container is moved in a constant position relative to the harvesting machine by way of a control device while the crop is being conveyed. The collecting container is preferably a filling device, by way of which uniform distribution of the crop in the collecting container (8) can be attained.
US08814638B2 Variable duct apparatus
A variable duct apparatus that controls outside air flowing in to a radiator includes a variable louver that is provided so as to extend in the vehicle width direction between a grille opening and a radiator of a vehicle, and regulates the amount of outside air admitted to the radiator, a lower louver that is provided so as to extend in the vehicle width direction between an air inlet and the radiator, and regulates the amount of outside air admitted to the radiator, and a link mechanism that coordinates and synchronizes the variable louver and the lower louver with each other, and interrupts the coordination between the variable louver and the lower louver upon application of an external force to the lower louver to thereby permit swinging of the lower louver.
US08814634B2 Conveying apparatus and a blasting machine
This invention provides a conveying apparatus and a blasting machine equipped with the conveying apparatus that can prevent workpieces from being damaged by the used abrasives attached to the conveying rollers.For the conveying apparatus, a peripheral part 33a disposed at the peripheral surface of a rolling member 33 of a rolling roller 31 is made of a softer elastic material than the material of the panel P, wherein when used abrasives get stuck between the peripheral part 33a of the rolling member 33 and the panel P, since the peripheral part 33a acts as a cushioning material that can reduce the force caused by the used abrasives and loaded on the panel P, even if the panel P is made of a fragile material, such as glass, the panel P can be conveyed without flaws being caused by the used abrasives.
US08814631B2 Tracking spectrum features in two dimensions for endpoint detection
A method of polishing includes polishing a substrate, receiving an identification of a selected spectral feature to monitor during polishing, measuring a sequence of spectra of light reflected from the substrate while the substrate is being polished, determining a location value and an associated intensity value of the selected spectral feature for each of the spectra in the sequence of spectra to generate a sequence of coordinates, and determining at least one of a polishing endpoint or an adjustment for a polishing rate based on the sequence of coordinates. At least some of the spectra of the sequence differ due to material being removed during the polishing, and the coordinates are pairs of location values and associated intensity values.
US08814628B2 Toy vehicle track set
A toy track set for a toy vehicle is disclosed herein, the toy track set having: a first track path comprising a first looped vehicle path; a second track path comprising an alternate vehicle path, the second track path having a first segment and a second segment, the second segment being separated from the first segment by a gap, the second segment being pivotally mounted to the track set for reciprocal movement between a first position and a second position, wherein a toy vehicle travelling along the second track path from the first segment to the second segment will travel along a first portion of the second segment when the second segment is in the first position and the toy vehicle traverses the gap and wherein the toy vehicle travelling along the second track path from the first segment to the second segment will be captured in a receiving area of the second segment when the second segment is in the second position and the toy vehicle traverses the gap; a track diverter pivotally mounted to the track set for movement between a first position and a second position wherein the toy vehicle travelling along the first track path will remain on the first track path when the track diverter is in the first position and wherein the toy vehicle travelling along the first track path will be diverted to the second track path when the track diverter is in the second position; and a booster for propelling the toy vehicle along either the first track path or the second track path.
US08814627B2 Toy set, game control program, and game device and toy communication system
A toy set that enables communication between a game device and a toy without changing a hardware configuration of the game device includes a program stored in a storage medium that when executed causes the game device to detect a sequence of single frequency sounds, output a voice corresponding to a combination of the detected sounds, generate a plurality of single frequency sound and generate a control signal by a combination of the sounds. The toy incorporates a sound generation means, a voice input means, a control means and a sensing means. The control means includes a generation means for generating a control signal as a sequence of plurality of single frequency sounds sent out from the sound generation means of the toy. When the control signal is inputted from the game device, the toy performs a predetermined action which corresponds to the control signal.
US08814626B2 Expanding and contracting yo-yo
The expanding and contracting yo-yo is a spool formed by a pair of disks connected by a narrow diameter pin having a string wound around the pin. At least one, and preferably both, of the disks has a plurality of overlapping wings (also referred to as air foils or leaves) pivotally attached to the periphery of the outer face of the disk. A biasing member causes the wings to remain in a closed dome configuration until the disks begin to spin. When the yo-yo is dropped and pulled back in, centrifugal force, centripetal force, alternate lift and drag of air flow, and resilient bias cause the wings to alternately pivot and unfold outward, followed by pivoting inward to a dome shape. In an alternative embodiment, the wings may be formed with a resilient living hinge that permits the wings to expand and contract against the body of the yo-yo.
US08814625B1 Tactile, visual and aural toy for entertainment and learning
A tactile, visual and aural toy for entertainment and learning includes a base with receptacles for receiving a corresponding three dimensional shapes. Each shape is provided with lights and sounds which are energized when motion of the shape is detected. The placing of the first shape in its corresponding receptacle determines which musical rendition will be played by the base when all of the receptacles have been filled by their correct corresponding three dimensional shape. The three dimensional shapes may be coordinated with sections of the base related to a particular receptacle by color or animal. The base also provides a light show visible through a translucent dome on the base. The particular light show which occurs is determined in the same manner as the determination of which musical rendition is played.
US08814616B2 Autonomous vehicle with fuel cell and autonomous flushing system
An autonomous aquatic vehicle with one or more fuel cells, a controller, a plurality of sensors, a battery, and at least one electric motor and propeller. The one or more fuel cells provide power to the battery, and the battery provides power for the vehicle. Seawater is provided to anodes of the fuel cell and air or oxygen is provided to the cathode to produce power for supply to the battery. The seawater-anode reaction creates waste or byproduct that tends to decrease output of the fuel cell. The waste or byproduct is automatically flushed from the fuel cell using seawater.
US08814615B2 Outboard motor
In an outboard motor having a prime mover, a gear mechanism transmitting a driving force of the prime mover to a propeller, and a gear case housing the gear mechanism, it is configured to have a drain bolt fastened to a drain hole bored at the gear case and constituted as a magnetic member; a stacked portion provided at an exposed part of the drain bolt in an inside of the gear case and having a conductor, an insulator and a resistive element partially making contact with the conductor that are stacked in a gravitational direction; a current detector detecting a current value conducted from the conductor to the drain bolt under a condition where voltage is applied to the conductor; and a wear debris amount detector adapted to detect an amount of wear debris of the gear mechanism deposited at the drain bolt based on the conducted current value.
US08814613B2 Ventilation control system
An aeration control system and method for a marine vessel. The system includes a valve configured to be coupled to an aeration conduit of a marine vessel. The valve is configured to be responsive to a valve control signal having a first value so as to be open and to provide air to the aeration conduit, and the valve configured to be responsive to the valve control signal having a second value so as to be closed and not provide air to the aeration conduit. The aeration control system also includes a control device, electrically coupled to the valve, that provides the valve control signal to the valve.
US08814612B2 Crimp terminal
A conductor crimp portion (11) before being crimped to a conductor of an electric wire includes, in an inner surface (11R) of the conductor crimp portion (11), circular recesses (20) as serrations of the conductor crimp portion (11) scattered to be spaced from each other. Each of the recesses (20) is formed through a press machining of the conductor crimp portion (11) by using a metal mold (70) with a protruded portion (72) formed, by a discharge machining, in a position corresponding to each of the recesses (20) or by using a metal mold with a protruded portion (85) formed, by press fitting a pin (83) into a press fit hole (82) formed in a block (81), in a position corresponding to each of the recesses (20).
US08814611B2 Crimp terminal
A conductor crimp portion (11) includes, in an inner surface (11R) of the conductor crimp portion (11), circular recesses (20) as serrations of the conductor crimp portion (11) scattered to be spaced from each other. Each of the recesses (20) before crimping has an elliptical shape (oval shape) having a minor axis oriented in a front-rear direction and a major axis oriented in a direction orthogonal to the front-rear direction, to take on a shape close to a perfect circle after crimping.
US08814599B2 Cable connector assembly with a crimping ring
A cable connector assembly comprises an insulative housing (1), a number of contacts (2), a cable (6) electrically connected with the contacts, and a metallic shell (3) enclosing the insulative housing. The insualtive housing includes a base portion (11) and a tongue portion (12) extending forwardly from the base portion. The metallic shell comprises a front shell (31) and a rear shell (32) combined with each other, the rear shell defines a pair of continued portions (322) extending backwards from an upper surface and a lower surface thereof, the continued portions is pressing on the cable, and the cable connector assembly further has a crimping ring (7) enclosing on the continued portions and the cable.
US08814595B2 High speed, high density electrical connector
A broadside coupled connector assembly has two sets of conductors, each separate planes. By providing the same path lengths, there is no skew between the conductors of the differential pair and the impedance of those conductors is identical. The conductor sets are formed by embedding the first set of conductors in an insulated housing having a top surface with channels. The second set of conductors is placed within the channels so that no air gaps form between the two sets of conductors. A second insulated housing is filled over the second set of conductors and into the channels to form a completed wafer. The ends of the first and second sets of conductors and the blades are jogged in both an x- and y-coordinate to reduce crosstalk and improve electrical performance.
US08814593B2 Connecting element for data lines
Connecting element for data lines with a body with a receiving section with recesses for receiving wires of the data lines, whereby electrical conductors are disposed on the body, whereby the conductors are guided from the recesses to a contact area, whereby the electronic circuit is connected with the conductors, whereby the element is made of molded material.
US08814592B2 Hyperfrequency connection assembly having a body with an inner passage for accommodating a conductive rod surrounded by an insulating ring
The hyperfrequency connection element according to the invention, designed to be electrically connected with a complementary connector, comprises: a body having an inner passage surrounding a central axis, a monolithic conductive contact rod extending along the central axis, an insulating ring surrounding the central axis, The body includes at least one hole that connects an outer surface of the connector to the inner passage. The ring is solid and deformable and includes an outer peripheral slot communicating with the hole. A resin securing the ring with the body is housed in the hole and in the slot of the ring, and the ring is removable before the resin is housed in the hole and in the slot of the ring.
US08814590B2 Electrical connector for flexible LED strip seal
An electrical connector for a flexible LED strip seal comprises a metal body (9) which clamps an end of the strip of flexible material (2) previously covered by a hood made of flexible material (8), and a contact casing (10) made of plastics material mounted on the metal body (9) and movable relative thereto from a raised inoperative position into a lowered operative position in which the contact elements (14) carried by the contact casing (10) pierce the flexible material of said hood (8) and of said strip (2) and contact conductive pads (6) of a PCB (4) incorporated in the LED seal (2).
US08814585B2 Electrical connector having a positioning protrusion with a slanted guiding surface
An electrical connector mountable on a printed circuit board and adapted for mating with a complementary connector, includes an insulating housing and a plurality of contacts. The insulating housing defines a base section, an upper and a lower walls extending forwardly from the base section, and a receiving space defined between the upper and the lower walls. Each contact has a main portion, a contacting portion extending from the main portion and exposed to the receiving space, and a tail portion extending outside of the insulating housing. A positioning protrusion is formed on an inside face of the lower wall and extends into the receiving space, and defines a slanted guiding surface therealong opposing to the upper wall to guide an insertion or rejection of the complementary connector.
US08814584B2 Wet-mateable electrical connector
A wet-mateable electrical connector comprises a vertically movable female connector unit 52 locatable over a vertically fixed male connector unit 50. The female connector unit 52 defines a chamber 62 containing a gas to exclude water and the like therefrom and having a closed upper end and an open lower end for receiving an upper end of the male connector unit 50. An insulating sheath 6 is locatable within the upper end of the female connector unit 52 to move it from a first position that protects a first electrical contactor 4 provided on the upper end of the male connector unit 50 to a second position that exposes the first electrical contactor 4. The upper end of the female connector unit 52 houses a second electrical contactor 3 which is engageable with the first electrical contactor 4 upon movement of the insulating sheath 6 from the first position to the second position.
US08814581B2 Lever type connector
A lever type connector in which workability in inserting terminals is enhanced is provided. A lever type connector 1 includes a connector housing 22 for containing terminals 61 at terminal ends of wires, and a lever 30 which is rotatably mounted on the connector housing 22, and rotated at a wire extending side of the connector housing 22 thereby to move a mating connector to be engaged with the connector housing 22 up to a normally engaged position. The lever 30 includes a pair of arm parts 31 (31a, 31b), and a connecting part 38 for interconnecting respective base end parts 51 (51a, 51b) of the arm parts 31. A recess part 53 for enlarging a distance between the base end parts 51 is provided on at least one of inner walls 50 (50a, 50b) of the base end parts 51 of the arm parts 31 which are opposed to each other.
US08814577B2 Electric connecting structure between substrate and electric component and method of connection between substrate and electric component
An electric connecting structure between a substrate and an electric component includes a substrate mounted in a case, an electric component assembled to a member which the case is mounted, a bus bar fixed to the case and connected to an electric circuit on the substrate at its one end and a spring disposed in compressed state between the bus bar and an electrode formed on the electric component. The substrate is electrical lyconnected to the electric component through the bus bar and the spring and a held portion formed on the spring is held by a spring holding portion integrally formed on the bus bar.
US08814574B2 Male end of a telemetric transceiver
The present invention relates to an electronic device which has a male connection portion for connection with a female snap. The male connection portion comprises a conductive stud which is or can be screwed in to a portion of the electronic device via threading on the stud. Furthermore, an adhesive can be added to the stud or an opening of the electronic device in order to provide a secure and water tight seal between the stud and the electronic device. The stud generally makes an electrical connection between a conductive portion of the female snap and an electronic component within the electronic device. The male portion of the stud may also comprise a cavity or opening for receiving a tool for screwing the stud in to the electronic device and/or for receiving a guiding pin of the female snap portion.
US08814573B2 Cutaneous surgical training model of the head, neck and shoulders
The present invention relates to a high-fidelity three-dimensional surgical training model for demonstrating or practicing surgical techniques. The three-dimensional surgical training model simulates human tissues of the head, neck and shoulders. The three-dimensional surgical training model may comprise a wide variety of defects, including but not limited to various cutaneous defects. The present invention also relates to methods of building and utilizing a three-dimensional surgical training model.
US08814566B2 Prophy angle
The present invention provides a dental prophylaxis angle that includes a housing, a rotor disposed in the housing, and a drive shaft driving the rotor. The drive shaft and the rotor operate together with a sidewall of the housing against a common surface of the rotor to prevent removal of the rotor from the housing in a direction along an axis of rotation of the rotor.
US08814565B1 Surgical device for dental implant installation
This invention provides the safe elevation of the Schneiderian membrane for the tissue regeneration especially bone augmentation for dental implant before surgical placement of the dental implants in the grown maxillary jaw bone in order to obtain adequate volume of osseous structure by addition of the artificial bone draft material. A surgical device can include a main portion, a handle portion, a main element, an adjustment mechanism, an adjustment portion, an outer thread, a free end, a depth measurement marks, the first and second connection sections, a cylinder, the inner and outer threads, the first and second projections, and a handle element with a texture.
US08814562B2 Igniter/thruster with catalytic decomposition chamber
An ignition system and method of igniting the ignition system includes a main catalyst section in a staged relationship with a pilot-catalyst section to stage a decomposition though the pilot-catalyst section which preheats the main catalyst section.
US08814561B2 Method and apparatus for controlling operation of oxyfuel combustion boiler
Stable operation of oxyfuel combustion boiler is ensured and amplification in likelihood of or downsizing of forced draft fan is attained. Upon change of commanded boiler load from start value to target value by target time, a feed amount of oxygen from oxygen producing device is regulated for attainment of oxygen concentration on entry side of the boiler body from reference value to attainment point or target entry-side oxygen concentration within entry-side oxygen concentration regulation range by target time. After attainment to attainment point, control is made to return entry-side oxygen concentration to reference value at return point. Airflow rate of forced draft fan is controlled with change rate smaller than change rate with which air flow rate of forced draft fan reaches target value by target time.
US08814560B2 Device and method for stabilizing the pressure and the flow of a gaseous mixture supplied to a surface-combustion cylindrical burner
The invention relates to a gas burner comprising a perforated cylindrical wall used as a combustion surface, a bottom wall and an inlet opening through which a combustible gaseous mixture is fed inside the burner. The stabilisation device consists of a grid (4a) that can be positioned in the inlet opening of the burner, and that comprises a central ring (5a) surrounded by a series of diverting vanes (6), the grid being thus configured so as to allow the free passage of the central portion of the flow of gaseous mixture entering the burner through the central ring (5a) while said diverting vanes (6) generate an eddy movement in the peripheral portion of the flow entering the burner from the outside of the central ring (5a).
US08814548B2 Mold assembly
A mold assembly that forms an expansion molded body by expanding foam raw material inside a cavity, includes a first die, a second die that closes together with the first die, wherein a sealed cavity is formed between the first die and the second die when the first die and the second die are closed, and a sealing member that is provided on at least one of the first die or the second die and seals the cavity, wherein at least one of a first space that is on a side of the sealing member that faces the cavity and leads to the cavity, or a second space that is formed inside the sealing member and leads to the cavity, is formed when the first die and the second die are closed.
US08814545B2 Scroll-rotation prevention assembly of scroll compressor
A scroll-rotation prevention assembly of a scroll compressor includes a fixed scroll, an orbiting scroll and an Oldham ring. The fixed scroll is positioned in the compressor and has a body. Two blocks extend from the periphery of the body. The orbiting scroll is disposed to correspond to the fixed scroll and has a main body. Two protrusions extend from the periphery of the main body. The Oldham ring is sandwiched between the body of the fixed scroll and the main body of the orbiting scroll. The Oldham ring has a first surface provided with a pair of first troughs and a second surface opposite to the first surface. The second surface is provided with a pair of second troughs. Each protrusion is slidably connected in the first troughs. Each block is slidably connected in the second troughs. Thus, the wear of the Oldham ring can be reduced.
US08814543B2 Conveying device for a fluid using an oscillating body arrangement
The invention relates to a conveying device for conveying a fluid in a conveying direction having one or more drive bodies which can be driven in an oscillating manner by means of a drive system transversely to the conveying direction. An acceleration of the fluid is achieved by a corresponding movement in translation or by a partially pivoting movement of the drive bodies in the manner of the fin principle known from biology (e.g. aerodynamics and hydrodynamics).
US08814540B2 Compressor system and frame
A reciprocating compressor is provided. In one embodiment, a reciprocating compressor frame includes a central body and at least two crosshead guides extending from opposite sides of the central body. Additionally, the compressor frame crosshead guide support structures extending outwardly from the central body along a respective crosshead guide. Other embodiments of compression systems, devices, and frames of such systems are also provided.
US08814536B2 System and method for a variable home position dispense system
Embodiments of the invention provide a system, method and computer program product for reducing the hold-up volume of a pump. More particularly, embodiments of the invention can determine, prior to dispensing a fluid, a position for a diaphragm in a chamber to reduce a hold-up volume at a dispense pump and/or a feed pump. This variable home position of the diaphragm can be determined based on a set of factors affecting a dispense operation. Example factors may include a dispense volume and an error volume. The home position for the diaphragm can be selected such that the volume of the chamber at the dispense pump and/or feed pump contains sufficient fluid to perform the various steps of a dispense cycle while minimizing the hold-up volume. Additionally, the home position of the diaphragm can be selected to optimize the effective range of positive displacement.
US08814532B2 Ejector
A nozzle of an ejector depressurizes and injects fluid, which is supplied to the nozzle. The nozzle is received in a receiving space of a body. The nozzle and the body are formed by press working. The nozzle includes nozzle-side ribs, which extend in an axial direction and project radially outward. The body includes body-side ribs, which extend in the axial direction and project radially outward. In a predetermined cross section of each of the nozzle and the body, which is perpendicular to the axial direction and includes the corresponding ribs, the nozzle or the body is formed seamlessly as a continuous single piece member.
US08814531B2 Pressure washers including jet pumps
A pressure washer includes a prime mover, a water pump, the water pump including a pump inlet for receiving fluid from a fluid source and a pump outlet for supplying a pressurized primary fluid, a jet pump including a primary fluid inlet fluidly coupled to the pump outlet, a secondary fluid inlet, and a fluid outlet, and a spray gun configured to be fluidly coupled to the fluid outlet of the jet pump, the spray gun including a spray gun outlet having a variable effective flow area. Wherein, in operation, in a high pressure operating mode, the pressurized primary fluid flows through the jet pump and exits through the fluid outlet of the jet pump, and in a high flow operating mode, the pressurized primary fluid flows through the jet pump and entrains a secondary fluid supplied through the secondary fluid inlet, resulting in a combined fluid flow.
US08814519B2 Fan, method for assembling a fan wheel and device
The present invention relates to a fan, to a method, and to a device for assembling the fan. The fan has an axis of rotation, which is connected to a dog, wherein the dog is connected to a fan wheel, wherein the dog, in a first number of contact surfaces, is in contact with additional contact surfaces of the fan wheel, wherein the dog and/or the fan wheel have more than the first number of contact surfaces and/or additional contact surfaces, wherein at least two contact surfaces have different height positions with respect to a central axis of the dog and/or the fan wheel.
US08814518B2 Apparatus and methods for cooling platform regions of turbine rotor blades
A platform cooling arrangement in a turbine rotor blade having a platform at an interface between an airfoil and a root, wherein the rotor blade includes an interior cooling passage that extends from a connection at the root to the approximate radial height of the platform, wherein, the interior cooling passage comprises a high-pressure coolant region and a low-pressure coolant region, and wherein a pressure side of the platform comprises a topside extending circumferentially from the airfoil to a pressure side slashface. The platform cooling arrangement may include: a platform cavity formed within the pressure side of the platform, a high-pressure connector that connects the platform cavity to the high-pressure coolant region of the interior cooling passage; a low-pressure connector that connects the platform cavity to the low-pressure coolant region of the interior cooling passage; and a pin bank formed within the platform cavity that includes radial pins.
US08814513B2 Ceiling mounted ventilation fan with illumination
A ceiling mounted ventilation fan with illumination capable of suppressing conduction of noise to inside of a room is provided. In the fan, a restriction member is provided for restricting passage of air between a lighting cover and a periphery of a lighting part, the lighting cover having a reflecting surface for reflecting light from the lighting part to lead the light to the inside of the room. A gap for air intake is formed between a lower end of the lighting cover and an edge of the indoor-side opening. Thus, air introduced into the main housing through the gap is discharged into the duct by the fan unit and conduction of noises produced by the fan unit to the room inside with the noise directivity enhanced in the lighting cover can be suppressed by the restriction member, so that conduction of noise to the room inside can be suppressed.
US08814505B2 Mechanical arrangement
A mechanical arrangement for an engine having two propeller stages, including: a first epicyclic gear stage including a sun gear, a planet gear, a planet carrier and an annulus, wherein the sun gear is driven by a shaft of the engine, the planet carrier is stationary and thereby permits static structure to be located there through, and the annulus outputs torque and/or drive; a second epicyclic gear stage including a second sun gear, a second planet gear, a second planet carrier and a second annulus, wherein the second sun gear is driven by the annulus of the first epicyclic gear stage and is annular to accommodate the static structure, the second planet carrier includes the output to one of the propeller stages and the second annulus includes the output to the other of the propeller stages; wherein the static structure provides mounting for static components on one or both sides of each epicyclic gear stage.
US08814502B2 Dual input drive AGB for gas turbine engines
A mechanical drive system of an aircraft gas turbine engine includes a tower shaft operatively connected to first and second shafts in an accessory drive gearbox. The first shaft rotates at a rotational speed lower than the rotational speed of the tower shaft and the second shaft rotates at a rotational speed equal to or higher than the rotational speed of the tower shaft.
US08814490B2 Article storage facility
An article storage facility is provided, which can reduce required space for installation in the rack fore and aft direction while preventing the configuration to become more complex. An article storage rack 2 having a plurality of storage units 1 arranged in a vertical direction and in a lateral direction, and an article transport device 4 which can transport articles 3 to each storage unit 1 in the article storage rack 2 are provided. The article transport device 4 consists of a movable body 12 movable in the rack lateral width direction of the article storage rack 2, a vertical movement guiding mast 13 movable in the rack fore and aft direction of the article storage rack 2 with respect to the movable body 12, and an article support 14 which is movable to a projected position for article transfer for the storage unit 1 and to a pulled back position away from the storage unit 1 by a movement of the vertical movement guiding mast 13 in the rack fore and aft direction and which is guided and supported by the vertical movement guiding mast 13 for vertical movement.
US08814489B2 Substrate processing system and substrate processing method
A substrate processing system includes a processing chamber that performs a preset process on a plurality of substrates in a batch-type manner; a substrate mounting table, installed within the processing chamber, configured to mount the plurality of substrates on a concentric circle and configured to be rotatable forward and backward; substrate accommodation units configured to accommodate the plurality of substrates in multi-stages in a vertical direction; substrate holders and configured to transfer the substrates between the substrate accommodation units and the processing chamber; elevating mechanisms configured to move the substrate accommodation units up and down. Unprocessed substrates are mounted on the substrate mounting table while the substrate mounting table is being rotated in one direction. After the completion of the processing of the substrates, unloading of processed substrates and loading of new unprocessed substrates are performed while the substrate mounting table is rotated in the another direction.
US08814481B2 Oil supply device for hole cutting apparatus
An inner cylinder, a pin, and a valve body are movable in a reciprocating manner in a direction along the rotational axis in relation to an oil supply pipe. At a proximate position, where a cutter attaching portion is close to the oil supply pipe, a rod portion of the valve body is supported by a pressure receiving portion of the holder inner cylinder due to the elastic force of a compression coil spring, such that an opening-closing portion of the valve body closes a valve port of the oil supply pipe. At a separated position, where the cutter attaching portion is separated from the oil supply pipe, the rod portion of the valve body is supported by the upper end of the pin due to the elastic force of the compression coil spring, instead of the pressure receiving portion, such that the opening-closing portion opens the valve port.
US08814478B2 Tool for turning/turn broaching or external milling of work pieces
The invention relates to a tool for turning/turn broaching or external milling of work pieces rotating about longitudinal axes during machining, comprising a disc-shaped tool support having cassettes (20) disposed peripherally thereon, each of said cassettes containing a cutting insert (12, 13, 14), said cassettes being fastenable to a circular, partially circular or segmented removable support (11) that is fastened either directly to a machine spindle or indirectly to a machine spindle by way of an adapter. According to the invention, the cassette (20) comprises a plate seat with a seating surface (21) and two lateral surfaces (22, 23) as contact surfaces for the cutting insert (12, 13, 14) and can be radially adjusted by way of an adjustment member (27) and can be fastened by way of a clamping member (18); the cassette (20) further comprises a slit-shaped groove (30) parallel to the seating surface (21) for the cutting insert (12, 13, 14), said groove having opposing groove walls with a distance and angle with respect to one another that are adjustable by way of an adjustment screw (33) such that the angular position of the seating surface (20) can be changed.
US08814476B2 Method, system, use of the system and reinforcement member for rock reinforcement
The present invention concerns a method, a system, the use of the system and a reinforcement member for the direct detection of the presence of a cavity in a drill-hole intended for the reception of a reinforcement member. The method comprises the injection of a drill-hole with hardening grout 6, the introduction of a reinforcement member 7, 40 to introduce a pressurized medium 37 and the measurement of the change in pressure or the detection of a flow of medium, whereby the fall in pressure or the presence of a flow of medium indicates the presence of a cavity. The system comprises a container 26 comprising a pressurised medium 37, a reinforcement member 7, 40 comprising a channel 15, 41 through which the pressurised medium in the container is added to the drill-hole at the presence of a cavity, and a pressure gauge 27 or a flow meter 50, where the pressure gauge measures a change in pressure or the flow meter detects a flow of medium, whereby a fall in pressure or a flow of medium indicates the presence of a cavity. The invention is used during the construction of tunnels and mines in order to ensure the quality of rock reinforcement that has been carried out.
US08814459B1 Adjustable adaptor kit for recessed can fixtures
An adaptor kit or system for use with conventional can light fixtures to adapt the can light fixture for use as a hanger assembly for auxiliary fixtures such as a hanging lamp, a flush-mounted lamp, or the like includes a stem member received within a stem-receiver. The stem-member includes a plurality of axial spaced detent positions and the stem-receiver includes a resilient spring clip the yieldable engages a one of the available detent position. Application of a sufficient axial force causes the spring clip to disengage with a current detent and re-engage with another detent to allow controlled extension thereof by an installer.
US08814455B2 Two-dimensional cosmetic system and method with applicator
A cosmetic device for applying makeup onto the lip area. The cosmetic device includes a top layer. The top layer includes a cosmetic applicator. The cosmetic device also includes a bottom layer aligned with and attached to the top layer. The top and bottom layers are attached in a two-dimensional manner so as to seal the cosmetic applicator and a product area between the top and the bottom layer.
US08814452B2 Printer and associated ejection assembly
An ejection assembly for a printer is provided, the ejection assembly being disposed downstream of a print head in order to receive web from the print head. The ejection assembly can include an ejection roller and a door having a closed configuration and an open configuration. The door can be biased toward the closed configuration and toward the ejection roller. Upon rotation of the ejection roller, the ejection roller can force the door from the closed configuration to the open configuration and can eject web past the door from the printer. In some embodiments, the ejection roller is rotated one full cycle, the ejection roller permits accumulation of web received from the print head and subsequently forces the door from the closed configuration to the open configuration and ejects the accumulated web past the door from the printer. Also provided are a corresponding printer and method.
US08814447B1 Moveable lens assembly within a display bezel of a computing device
In one general aspect, the computing device can include a base portion, and a display portion moveably coupled to the base portion, the display portion including a display bezel and an image sensor disposed within the display bezel. The computing device can also include an extension member coupled to the display portion and associated with a lens. The extension member can be configured to move at least a portion of the lens in a direction away from the image sensor to a position disposed outside of the display bezel and to move the portion of the lens in a direction towards the image sensor to a position disposed within the display bezel.
US08814441B2 Optical connector
An optical connector (10), in particular for outside use, for detachably connecting at least two optical cables along a connector axis (43) comprises a socket portion (11) and a plug portion (27), which portions are substantially of cylindrical design with respect to the connector axis (43), can be detachably plugged into one another along the connector axis (43) and can be locked in the plugged-in state. A locking mechanism (19, 20, 32, 33, 36, 46), which is equipped with a latch function and which latches automatically during insertion is provided for the purposes of rapid locking.
US08814439B2 Bearing assembly, clutch assembly and constant velocity transmission
A bearing for engaging an associated shaft and an associated body for axial movement on the associated shaft which includes a housing; a first set of a plurality of mounting shafts carried by said housing, each mounting shaft in said first set of a plurality of mounting shafts having a center line; and a first set of a plurality of rollers, each roller being carried a respective one of said plurality of mounting shafts and mounted for rotation about the centerline of the respective mounting shaft, each roller being dimensioned and configured for abutting relationship with the associated shaft.
US08814437B2 Roller bearing cage and method for the production thereof
A method for producing a roller bearing cage (1) is provided, including the following steps: a base body (2) which is close to a net shape is produced by a stereolithography method or by a 3D-printing method, and the provided base body (2) is coated with a thin, nanocrystalline coating (3). A roller bearing cage, including a base body (2) and a nanocrystalline coating (3) fixed to the base body (2) produced by this method is also provided. This method is suitable for producing roller bearing cages in only small quantities in a small series.
US08814435B2 Bearing unit
A bearing unit includes an outer ring member having an outer periphery on which a flange portion is formed, the flange portion being fitted to a vehicle body side; an inner ring member that is rotatably inserted in the outer ring member; and rolling elements in double rows, which are rollably arranged between the outer ring member and the inner ring member, wherein bolts are press-fitted in bolt holes formed in a peripheral edge portion of a wheel fitting flange that is formed on an outer periphery of the inner ring member, and a recessed portion is formed in an outer peripheral surface of the wheel fitting flange.
US08814433B2 Sliding component
A positive pressure generating mechanism comprising a positive pressure generating groove is provided to a high-pressure side of one of two sliding surfaces that slide relative to each other in a pair of sliding components, and a negative pressure generating mechanism comprising a negative pressure generating groove is provided to a low-pressure side. The positive pressure generating groove and negative pressure generating groove are communicated with a high-pressure fluid side and separated from a low-pressure fluid side by a seal surface.
US08814427B2 Instrumentation and method for optical measurement of samples
An optical measurement instrument includes one or more temperature sensors (122) arranged to measure sample well specific temperatures from sample wells (111-117) arranged to store samples (103-109) to be optically measured. A processing device (121) of the optical measurement instrument is arranged to correct, using a pre-determined mathematical rule, measurement results obtained by the optical measurements on the basis of the measured sample well specific temperatures. Hence, the adverse effect caused by temperature differences between different samples on the accuracy of the temperature correction of the measurement results is mitigated.
US08814419B1 Chesta vortex organizer
Blade systems mix fluids and/or air to create and organize unique vortexes. The vortexes periodically implode to provide superior mixing. The blade structures may comprise four fold lines upon a circular planar surface. The planar surface may be prepared by removal of just one small portion of material, the removed portion spanning approximately one radian of the perimeter.