Document Document Title
US08810118B2 Spark plug
A spark plug includes a tubular insulator, a center electrode, a tubular metal shell, a ground electrode, and a pillar body tip. The tubular insulator has an axial hole penetrating in the direction of an axis. The pillar body tip includes one end face that is welded to the ground electrode and another end face that forms a gap with a front end portion of the center electrode. The ground electrode includes a part where the tip is to be welded. The surface forms a clearance with a part including a constituent material of the tip. The ground electrode includes a surface where a plating layer is disposed. The plating layer covers a surface excluding a formation part of the clearance. The clearance has a size A that is equal to or more than 0.01 mm and equal to or less than 0.5 mm.
US08810114B2 Optical unit and organic light emitting diode display having the same
An optical unit on a light emitting unit includes a first polarizing plate on the light emitting unit, a second polarizing plate on the first polarizing plate, the second polarizing plate having a higher polarization degree than the first polarizing plate, and a plurality of phase shift plates between the first polarizing plate and the second polarizing plate.
US08810109B2 Piezoelectric actuator, motor, robot hand, and robot
A motor includes a vibrating plate having a projection part to be pressed against a driven member and a piezoelectric material provided on the vibrating plate, wherein a Young's modulus EL in the pressing direction of the vibrating plate and a Young's modulus ES in a direction crossing the pressing direction are different.
US08810104B2 Acoustic wave device and method for fabricating the same
A surface acoustic wave device includes a piezoelectric substrate, at least one interdigital transducer (IDT) electrode provided on the piezoelectric substrate, and an insulator layer to improve a temperature characteristic arranged so as to cover the IDT electrode. When a surface of the insulator layer is classified into a first surface region under which the IDT electrode is positioned and a second surface region under which no IDT electrode is positioned, the surface of the insulator layer in at least one portion of the second surface region is higher than the surface of the insulator layer from the piezoelectric substrate in at least one portion of the first surface region by at least about 0.001λ, where the wavelength of an acoustic wave is λ.
US08810102B2 Rotor for an electric machine with reduced detent torque
The invention relates to an electric machine, in particular to a generator for supplying the electrical system of a motor vehicle, comprising a laminated rotor (20) with an energiser winding (29), which provides the energisation for the machine preferably in conjunction with permanent magnets (24, 25) arranged on the rotor periphery. According to the invention, the rotor laminate bundle (21) is made up of at least two part bundles (21a, b) in the axial direction with grooves (40) running into each other and with poles offset relative to each other (32 to 38). A machine with reduced detent torque is thus obtained with grooves (40) aligned parallel to the axis, in which the energiser windings (29) can be placed with a high filling factor and without production difficulties and without the risk of damaging the winding insulation.
US08810099B2 Power magnetic planetary gear set
A power magnetic planetary gear set uses stator of a motor to provide electrically generated magnetic sections. The electrically generated magnetic sections are variable under the excitation control of coils and driver so that either the outer stator or the sun stator of the magnetic planetary gear set may be stationary and still provide self-revolutionary magnetic forces toward the planet gears disposed therebetween. The planet gears are also mounted on planet arms so as to revolve on their own axes and have orbital revolution with respect to the sun stator.
US08810098B2 Magnetic gear arrangement having a variable gear ratio
A magnetic gear arrangement is provided having a magnetically active gear member that generates a first magnetic field, which is modulated by interpoles. The modulated magnetic field generates magnetic poles on a magnetically passive gear member, and these poles form a second magnetic field. The material of the passive gear member is sufficiently magnetically hard that the first and second magnetic fields interact to couple the motion of the active and passive gear members according to a given gear ratio.
US08810095B2 Spindle motor with fluid dynamic bearing and storage disk drive
A dynamic pressure bearing is defined in a first gap between a shaft portion and a sleeve portion. An upper seal portion extending upward and a lower seal portion extending downward are arranged radially outward of the dynamic pressure bearing. Each of the upper seal portion and the lower seal portion includes a surface including a lubricating oil located therein. The upper seal portion and the lower seal portion are arranged in communication with each other through a communicating hole defined in the sleeve portion. The communicating hole and a space ranging from the upper seal portion to the lower seal portion through the first gap are filled with the lubricating oil. The axial distance between the surfaces of the lubricating oil in the upper seal portion and the lower seal portion is arranged to be shorter than the axial distance between an upper end and a lower end of the dynamic pressure bearing.
US08810094B2 Linear vibration motor
Disclosed herein is a linear vibration motor. The motor includes a stator and a vibrator. The stator includes a magnet. The vibrator includes a coil facing the magnet. A weight is coupled to the coil. A PCB is connected to the coil and the stator. An elastic member is coupled to stator and the coil. A damper is provided on the weight at a position facing the elastic member. The damper may be provided between the elastic member and the weight or between the elastic member and the inner surface of a casing. The damper can mitigate metallic high frequency noise attributable to friction between the elastic member and the weight or between the elastic member and the casing. Furthermore, the spatial utilization is increased, thereby enhancing the degree of freedom in designing the linear vibration motor.
US08810087B2 Motor unit
The invention relates to a motor unit (5) comprising a motor (1), a heat exchanger (2) and an inverter (3) for the motor (1). In order to provide a compact, low-cost motor unit it is proposed that the heat exchanger (2) is embodied for cooling both the motor (1) and the inverter (3).
US08810085B2 Electric power tool including a plurality of circuit boards
An electric power tool, which uses a DC brushless motor as a drive source and controls the DC brushless motor by a switching element, can include a tubular housing main body portion accommodating the DC brushless motor, and a grip portion protruding from a side portion of the housing main body portion. The switching element is arranged inside the grip portion, and is spaced apart from an electronic circuit board for an electronic component for operating the switching element.
US08810082B2 Linear motor
The invention relates to a small size and lightweight linear motor having small thrust ripples, in which the magnetic attraction working between an armature and a mover is canceled out and therefore is small. A thrust generation mechanism includes a stator (3) and a mover (5). The mover (5) includes permanent magnets (4) installed in a row so that the magnetic poles at the front and backsides of the magnets are alternately reversed along the traveling direction. The stator (3) includes upper and lower pole teeth (6), (7) having a plurality of magnetic poles (2) and arranged so as to sandwich the permanent magnets (4) of the mover (5), cores for connecting the pole teeth, and a winding (1) wound around a set of a plurality of the cores. Thrust ripples are reduced by adjusting the magnetic pole pitch (Pc) of the magnetic poles (2).
US08810080B2 Battery module of excellent structural stability
Disclosed is a battery module including a base plate on which unit modules, each with two or more secondary batteries therein, are stacked in a vertically erected state, a pair of end plates disposed in tight contact with outer surfaces of outermost unit modules while bottoms of the end plates are fixed to the base plate, and supporting bars connected between opposite sides of upper or side parts of the end plates so as to support the end plates, wherein each of the end plates includes a main body contacting a corresponding one of the unit modules, and a top wall, a bottom wall, and a pair of side walls protruding outward from the perimeter of the main body, the thickness of each of the side walls being increased from the top to the bottom wall, thereby dispersing pressure (bending load) from the unit modules and the supporting bars.
US08810078B2 Analog current output circuit
In the analog current output circuit according to the present invention, a rising start position and a tilt of an internal control voltage are set such that it crosses, at the maximum of an analog output current, a load end voltage obtained when the resistance of a load is the one near the center of a specification range. According to a comparison result in a comparator, a switch causes a DC/DC converter to input a high reference voltage and causes an output transistor to output a high power supply voltage when the internal control voltage is smaller than the load end voltage and causes the DC/DC converter to input a low reference voltage and causes the output transistor to output a low power supply voltage when the internal control voltage is larger than the load end voltage.
US08810076B2 Electrical appliance holder system
An appliance holder system for electrical handheld appliances of the type having a flexible electrical power cord attached thereto is provided. The appliance holder system includes an appliance holder assembly having at least one receptacle for receiving and storing at least one electrical handheld appliance having a flexible electrical power cord attached thereto. A power cord storage assembly of the system has a pair of spaced apart cord wrapping elements about which the flexible electrical power cord may be wrapped for storage. At least one of the cord wrapping elements is movable between a storage and release position. The cord wrapping elements are configured to retain the wrapped power cord upon the power cord storage assembly when the at least one of the cord wrapping elements is in the storage position and wherein the wrapped power cord may be removed from the power cord storage assembly without unwrapping the wrapped power cord when the at least one of the cord wrapping elements is moved to the release position.
US08810075B2 Power off delay circuit and power supply system
A power off delay circuit includes a first diode with an anode receiving input power and a boost transformer circuit connected to a cathode of the first diode. The boost transformer circuit outputs power signals to a load circuit, and includes a capacitor, a primary winding, a first secondary winding, and a second secondary winding. The capacitor is charged when an input power is on, and discharges when the input power is off. The first secondary winding boosts power flowing through the primary winding and the first switch branch to charge the capacitor via the third switch branch when the input power is on. The capacitor discharges via the second secondary winding and the fourth switch branch when the input power is off, and the primary winding boosts discharging power of the capacitor, and outputs boosted discharging power to the load circuit via the second switch branch.
US08810071B2 Wireless power transmission system
A Wireless power transmission system comprises a base unit (1) with multiple magnetic field generator circuits and a device (10), separable from said base unit (1) having a receiving inductor, adapted to receive power inductively when said device (10) is in proximity to one of said generator circuits, wherein said base unit (1) comprises a controller (3), configured to determine a transmission circuit (2′) from said generator circuits when said receiving inductor is in proximity to said transmission circuit (2′), whereupon said transmission circuit (2′) is operated to generate a first magnetic field (8), having a first phase, to induce a current in said receiving inductor and at least one of the remaining generator circuits is operated as a compensation circuit (2″, 52, 82) to generate a second magnetic field (21), having an opposite phase to said first phase.
US08810066B2 Power storage system and method of controlling the same
A power storage system and method of controlling the system is disclosed. The power storage system is connected to a power generation system and a grid. If a remaining amount of power of a battery is insufficient when the grid is in a quasi-normal state, the battery is charged by directly receiving electric power from the grid, and thus electric power is available for the if the grid subsequently goes back into the abnormal state.
US08810063B2 Power source connecting device
A power source connecting device includes an adapter, a rail and a plurality of power cables. The adapter connected to an external power source converts the alternating current output from the external power source to direct current. The rail electrically connects to the adapter. One end of each of the power cable connected to an electronic device, and another end of each of the power cable connects to the rail and is configured for slide along the rail together with the electronic device. The power cable remains in electrical connection with the rail during the sliding.
US08810060B2 Charging device for vehicle
A charging device for a vehicle includes a connector configured such that a coupler for transmitting electric power from an external power supply to the vehicle is connectable to the connector, a charging circuit for transmitting electric power from the connector to a power storage device, a charging control unit for charging the power storage device by controlling the charging circuit while in an operating state, and for halting control of the charging circuit while in a halting state, and an activation control unit for keeping the charging control unit in the halting state until detecting that the connector receives electric power, in a case where connection of the coupler and the connector is detected, and for switching the charging control unit from the halting state to the operating state when it is detected that the connector receives electric power.
US08810059B2 Effective low voltage to medium voltage transmission on PRIME band
Coupling and interface circuits for powerline modems are disclosed. A powerline modem may be coupled to a low voltage (LV) line or a medium voltage (MV) line using a circuit that is designed to compensate for signal attenuation and loss that is created by the a LV/MV transformer and/or a MV coupler. In one embodiment, separate coupling transformers may be used by the modem for reception and transmission. In other embodiments, a capacitance is switched on the transmission line before the modem transmits to lower the line impedance.
US08810053B2 Method and apparatus for efficient fuel consumption
A method for efficient fuel consumption comprises recharging batteries or operating a device carrying out a task, with an engine through an electrical connection. The method also includes monitoring at least one of (i) current in the electrical connection, (ii) voltage of the batteries, and (iii) length of time of the recharging or task, to determine if the recharging has reach a preselected endpoint or the task has been completed. The method further includes generating a signal through a communication link to cause the engine to stop operating by: (a) preventing operation of a spark plug, (b) preventing delivery of fuel to the engine, or (c) preventing delivery of oxygen to the engine.
US08810046B2 Silicone resin composition, encapsulating layer, reflector, and optical semiconductor device
A silicone resin composition contains a cage octasilsesquioxane having a group represented by the following formula (1), an alkenyl group-containing polysiloxane containing an alkenyl group having a number of moles larger than that of a hydrosilyl group in the cage octasilsesquioxane, a hydrosilylation catalyst, and an organohydrogenpolysiloxane. (where, in formula, R1 represents a monovalent hydrocarbon group selected from a saturated hydrocarbon group and an aromatic hydrocarbon group. R2 represents hydrogen or a monovalent hydrocarbon group selected from a saturated hydrocarbon group and an aromatic hydrocarbon group. The molar ratio of the monovalent hydrocarbon group:hydrogen in R2 in the cage octasilsesquioxane as a whole is, as an average value, in the range of 6.5:1.5 to 5.5:2.5).
US08810045B2 Packaging substrate and semiconductor package
A packaging substrate and a semiconductor package each include: a metal board having a first surface and a second surface opposite to the first surface, wherein the first surface has a plurality of first openings for defining a first core circuit layer therebetween, the second surface has a plurality of second openings for defining a second core circuit layer therebetween, each of the first and second openings has a wide outer portion and a narrow inner portion, and the inner portion of each of the second openings is in communication with the inner portion of a corresponding one of the first openings; a first encapsulant formed in the first openings; a second encapsulant formed in the second openings; and a surface circuit layer formed on the first encapsulant and the first core circuit layer.
US08810044B2 Dicing tape-integrated wafer back surface protective film
The present invention provides a dicing tape-integrated wafer back surface protective film including: a dicing tape including a base material and a pressure-sensitive adhesive layer formed on the base material; and a wafer back surface protective film formed on the pressure-sensitive adhesive layer of the dicing tape, in which the wafer back surface protective film is colored. It is preferable that the colored wafer back surface protective film has a laser marking ability. The dicing tape-integrated wafer back surface protective film can be suitably used for a flip chip-mounted semiconductor device.
US08810043B2 Semiconductor device
A semiconductor device includes a semiconductor element having a main surface where an outside connection terminal pad is provided. The semiconductor element is connected to a conductive layer on a supporting board via a plurality of convex-shaped outside connection terminals provided on the outside connection terminal pad and a connection member; and the connection member commonly covers the convex-shaped outside connection terminals.
US08810037B2 Semiconductor device and method for manufacturing the same
The semiconductor device includes a semiconductor substrate including a first region straightly connected to a cell string region and a second region adjacent to the first region, a first conductive pattern having a first pitch in the first region, a second conductive pattern connected to the first conductive pattern in the first region and having a structure in which S shaped characters are continuously connected in a zigzag shape, and a third conductive pattern spaced from the second conductive pattern in the second region and having an essentially oval shape in which a central portion thereof is divided. An exposure process margin is improved in an X-decoder region and a failure such as a bridge is reduced to improve characteristics of the semiconductor device.
US08810032B2 Semiconductor device and method for manufacturing of same
A method for manufacturing a semiconductor device, includes: forming a first metal layer on a semiconductor substrate, the semiconductor substrate including a diffusion layer; forming an insulating layer having an opening on the first metal layer; forming a second metal layer on the first metal layer in the opening of the insulating layer; removing the insulating layer; covering an exposed surface of the second metal layer with a third metal layer, the third metal layer including a metal having an ionization tendency lower than that of the second metal layer; and forming an electrode interconnect including the first metal layer, the second metal layer, and the third metal layer by removing the first metal layer using the third metal layer as a mask.
US08810031B2 Wafer-to-wafer stack with supporting pedestal
An electronic device having a stacked structure is provided. The electronic device includes a first electronic layer, a second electronic layer disposed on the first electronic layer, and at least a post. The first electronic layer has a first interface, and including a first substrate and a first device layer disposed on the first substrate. The first interface is located between the first substrate and the first device layer, and the first device layer has a surface opposite to the first interface. The post is arranged in the first device layer, and extending from the first interface to the surface of the first device layer.
US08810029B2 Solder joint flip chip interconnection
A flip chip interconnect has a tapering interconnect structure, and the area of contact of the interconnect structure with the site on the substrate metallization is less than the area of contact of the interconnect structure with the die pad. Also, a bond-on-lead or bond-on-narrow pad or bond on a small area of a contact pad interconnection includes such tapering flip chip interconnects. Also, methods for making the interconnect structure include providing a die having interconnect pads, providing a substrate having interconnect sites on a patterned conductive layer, providing a bump on a die pad, providing a fusible electrically conductive material either at the interconnect site or on the bump, mating the bump to the interconnect site, and heating to melt the fusible material.
US08810028B1 Integrated circuit packaging devices and methods
Integrated circuit packaging devices and methods are disclosed. An embodiment package lid is formed from a single piece of material. The lid includes a planar rectangular main body having a bottom surface, and a leg disposed at each corner of the main body and within a perimeter of the main body. Each leg has a wall projecting downwardly from the main body and a non-planar bottom surface disposed at a bottom of the wall. The non-planar bottom surface of the leg faces a same direction as the main body bottom surface.
US08810026B2 Semiconductor module
A semiconductor module which includes a semiconductor device; a wiring member that is connected to the semiconductor device; a cooling plate that includes a first surface on a side of the semiconductor device and a second surface on a side opposite to the first surface and has a fastening portion at an end thereof in a first direction; and a molded portion that is formed by molding a resin on the semiconductor device, the wiring member and the cooling plate, wherein the fastening portion is exposed out of the molded portion, and a terminal portion of the wiring member is exposed out of the molded portion such that the terminal portion of the wiring member extends in a second direction which is substantially perpendicular to the first direction.
US08810025B2 Reinforcement structure for flip-chip packaging
The present disclosure provides a carrier substrate, a device including the carrier substrate, and a method of bonding the carrier substrate to a chip. An exemplary device includes a carrier substrate having a chip region and a periphery region, and a chip bonded to the chip region of the carrier substrate. The carrier substrate includes a reinforcement structure embedded within the periphery region.
US08810021B2 Semiconductor device including a recess formed above a semiconductor chip
A semiconductor device, includes a substrate with a first surface, a semiconductor chip disposed over the first surface of the substrate, the semiconductor chip including a first region and a second region, and an encapsulant resin formed over the first surface of the substrate and encapsulating the semiconductor chip. The encapsulant resin has a thickness that is less at the first region of the semiconductor chip than that at the second region.
US08810014B2 Semiconductor package including conductive member disposed between the heat dissipation member and the lead frame
There is provided a semiconductor package including: a lead frame having an electronic component mounted on one surface thereof; a heat dissipation substrate disposed downwardly of the lead frame; an insulating member disposed upwardly of the electronic component such that the electronic components are electrically connected to one another; a conductive member disposed between the insulating member and the lead frame and electrically connecting the electronic component to the lead frame; and a molded portion hermetically sealing the insulating member and the heat dissipation substrate.
US08810013B2 Integrated power converter package with die stacking
An integrated circuit for implementing a switch-mode power converter is disclosed. The integrated circuit comprises at least a first semiconductor die having an electrically quiet surface, a second semiconductor die for controlling the operation of said first semiconductor die stacked on said first semiconductor die having said electrically quiet surface and a lead frame structure for supporting said first semiconductor die and electrically coupling said first and second semiconductor dies to external circuitry.
US08810007B2 Wiring board, semiconductor device, and method for manufacturing wiring board
A wiring board provided with a silicon substrate including a through hole that communicates a first surface and a second surface of the silicon substrate. A capacitor is formed on an insulating film, which is applied to the silicon substrate, on the first surface and a wall surface defining the through hole. A capacitor part of the capacitor includes a first electrode, a dielectric layer, and a second electrode that are sequentially deposited on the insulating film on the first surface and the wall surface of the through hole. A penetration electrode is formed in the through hole covered by the first electrode, the dielectric layer, and the second electrode of the capacitor part.
US08810006B2 Interposer system and method
A system and method for providing an interposer is provided. An embodiment comprises forming a first region and a second region on an interposer wafer with a scribe region between the first region and the second region. The first region and the second region are then connected to each other through circuitry located over the scribe region. In another embodiment, the first region and the second region may be separated from each other and then encapsulated together prior to the first region being connected to the second region.
US08810004B2 Methods, systems and devices for electrostatic discharge protection
A resistor-equipped transistor includes a package that provides an external collector connection node (114, 134), an external emitter connection node (120, 140) and an external base connection node (106, 126). The package contains a substrate upon which a transistor (102, 122), first and second resistors, and first and second diodes are formed. The transistor has an internal collector (118, 138), an internal emitter (120, 140) and an internal base (116, 136) with the first resistor (104, 124) being electrically connected between the internal base and the external base connection node and the second resistor (108, 128) being electrically connected between the internal base and the internal emitter. The first and second diodes are electrically connected in series between the external base connection node and the external collector connection node with the first diode (112, 132) having a first cathode-anode orientation that is opposite of a second cathode-anode orientation corresponding to the second diode (110, 130).
US08810002B2 Vertical metal insulator metal capacitor
A capacitor includes a first electrode. The first electrode includes a bottom conductive plane and a plurality of first vertical conductive structures. The bottom conductive plane is disposed over a substrate. The capacitor includes a second electrode. The second electrode includes a top conductive plane and a plurality of second vertical conductive structures. The capacitor includes an insulating structure between the first electrode and the second electrode. The first vertical conductive structures and the second vertical conductive structures are interlaced with each other thereby providing higher capacitance density.
US08810000B2 Semiconductor device comprising capacitive element
A capacitive element formed within a semiconductor device comprises an upper electrode, a capacitive insulating film containing an oxide and/or silicate of a transition metal element, and a lower electrode having a polycrystalline conductive film composed of a material having higher oxidation resistance than the transition metal element and an amorphous or microcrystalline conductive film formed below the polycrystalline conductive film.
US08809993B2 Semiconductor device having isolation region
A semiconductor device can include an isolation region that defines a plurality of active regions. The plurality of active regions can include an upper surface having a short axis in a first direction and a long axis in a second direction. The plurality of active regions can be repeatedly disposed along the first direction and along the second direction, and can be spaced apart from each other. The isolation region can include a first insulating layer being in contact with side walls of a short axis pair of active regions which can be the closest active regions in the first direction among the plurality of active regions, and continuously extending along a first shortest distance between the short axis pair of active regions.
US08809984B2 Substrate connection type module structure
The present invention provides a substrate connection type module structure comprising a substrate with a through hole structure and a first contact pad. A chip is configured on the through hole structure of the substrate, with a second contact pad and a sensing area. The first contact pad is coupled to the second contact pad via a wire. A second substrate is electrically connected to the first substrate. The second substrate and the chip are located at the same layer. A lens holder is disposed on the substrate, and a lens is located on the top of the lens holder. A transparent material is disposed within the lens holder. The lens is substantially aligning to the transparent material and the sensing area.
US08809983B2 Semiconductor device, manufacturing method therefor, and electronic apparatus
A semiconductor device includes: a first semiconductor chip; and a second semiconductor chip that is stacked on the first semiconductor chip. The first semiconductor chip includes a first wiring portion of which a side surface is exposed at a side portion of the first semiconductor chip. The second semiconductor chip includes a second wiring portion of which a side surface is exposed at a side portion of the second semiconductor chip. The respective side surfaces of the first wiring portion and the second wiring portion, which are exposed at the side portions of the first semiconductor chip and the second semiconductor chip, are covered by a conductive layer, and the first wiring portion and the second wiring portion are electrically connected to each other through the conductive layer.
US08809982B2 Robust high aspect ratio semiconductor device
The invention relates to an semi-conductor device comprising a first surface and neighboring first and second electric elements arranged on the first surface, in which each of the first and second elements extends from the first surface in a first direction, the first element having a cross section substantially perpendicular to the first direction and a sidewall surface extending at least partially in the first direction, wherein the sidewall surface comprises a first section and a second section adjoining the first section along a line extending substantially parallel to the first direction, wherein the first and second sections are placed at an angle with respect to each other for providing an inner corner wherein the sidewall surface at the inner corner is, at least partially, arranged at a constant distance R from a facing part of the second element for providing a mechanical reinforcement structure at the inner corner.
US08809973B2 Chip package comprising a microphone structure and a method of manufacturing the same
In various embodiments, a method for manufacturing a chip package is provided. The method includes arranging a chip over a substrate, the chip including a microphone structure and an opening to the microphone structure; and encapsulating the chip with encapsulation material such that the opening is kept at least partially free from the encapsulation material.
US08809970B2 Semiconductor device and method for manufacturing the same
A semiconductor device includes a semiconductor substrate, a source region, a drain region, an insulating film and a gate electrode. The source region is formed in the semiconductor substrate. The drain region is formed in the semiconductor substrate and being separate from the source region. The insulating film is formed between the source region and the drain region and on or above the semiconductor substrate. The insulating film includes lanthanum aluminate containing at least one element selected from Si, Ge, Mg, Ca, Sr, Ba and N. The lanthanum aluminate contains at least one element selected from Ti, Hf and Zr. The gate electrode is formed on the insulating film.
US08809969B2 Semiconductor device
A semiconductor device using one or more guard rings includes a p-type guard ring region surrounding a pn junction region, an insulating film covering the p-type guard ring region, one or more conductive films electrically connected with the p-type guard ring region through one or more contact holes made in the insulating film, and a semi-insulating film covering the insulating film and the conductive films. Thus, a desired breakdown voltage characteristic can be ensured even if a foreign matter or the like adheres to a surface of the conductive films.
US08809965B2 Semiconductor device
A semiconductor device includes a first MIS transistor and a second MIS transistor. The first MIS transistor includes first offset sidewalls formed on side surfaces in a gate width direction of a first gate electrode, second offset sidewalls formed on side surfaces in a gate length direction and the side surfaces of the gate width direction of the first gate electrode with the first offset sidewalls being interposed between the second offset sidewalls and the first gate electrode, and first extension regions. The second MIS transistor includes third offset sidewalls formed on side surfaces in a gate length direction and a gate width direction of a second gate electrode, fourth offset sidewalls formed on the side surfaces in the gate length and width directions of the second gate electrode with the third offset sidewalls being interposed between the fourth offset sidewalls and the second gate electrode, and second extension regions.
US08809964B2 Method of adjusting the threshold voltage of a transistor by a buried trapping layer
An electronic subassembly and associated method for the production of an electronic subassembly include a semiconductor layer bearing at least a first transistor having an adjustable threshold voltage is joined to an insulator layer and in which a first trapping zone is formed at a predetermined first depth. The first trapping zone extends at least beneath a channel of the first transistor and includes traps of greater density than the density of traps outside the first trapping zone, in such a way that the semiconductor layer and the first trapping zone are capacitively coupled. The useful information from the first transistor includes the charge transport within this transistor. A second trapping zone can be formed that extends at least beneath a channel of a second transistor that is formed by a second implantation with an energy and/or a dose and/or atoms that differ from those used to form the first trapping zone.
US08809962B2 Transistor with reduced parasitic capacitance
Scaled transistors with reduced parasitic capacitance are formed by replacing a high-k dielectric sidewall spacer with a SiO2 or low-k dielectric sidewall spacer. Embodiments include transistors comprising a trench silicide layer spaced apart from a replacement metal gate electrode, and a layer of SiO2 or low-k material on a side surface of the replacement metal gate electrode facing the trench silicide layer. Implementing methodologies may include forming an intermediate structure comprising a removable gate with nitride spacers, removing the removable gate, forming a layer of high-k material on the nitride spacers, forming a layer of metal nitride on the high-k material, filling the opening with insulating material and then removing a portion thereof to form a recess, removing the metal nitride layers and layers of high-k material, depositing a layer of SiO2 or low-k material, and forming a replacement metal gate in the remaining recess.
US08809960B2 Semiconductor device and method for manufacturing
A semiconductor device includes a gate structure penetrating an interlayer insulating layer formed on a semiconductor substrate, an epitaxial growth layer grown on the interlayer insulating layer, a first transistor including a first channel region in the semiconductor substrate formed by a bias applied to source/drain contacts penetrating the interlayer insulating layer, and a second transistor including a second channel region formed in the epitaxial growth layer by the bias applied to the source/drain contacts and sharing the gate structure. A current flowable path flows more current at any given time, so that operation current is increased and operation speed is improved. A smaller area of the semiconductor device is necessary to cause the current to flow, and the effective net die area is increased.
US08809956B2 Vertically oriented semiconductor device and shielding structure thereof
The present disclosure involves a semiconductor device. The semiconductor device includes a substrate; a capacitor disposed over the substrate; an inductor disposed over the substrate and having a coil feature surrounding the capacitor; and a shielding structure over the substrate and configured around the coil feature.
US08809955B2 Semiconductor structure and method for manufacturing the same
Semiconductor structures and methods for manufacturing the same are disclosed. The semiconductor structure comprises: a gate stack formed on a semiconductor substrate; a super-steep retrograde island embedded in said semiconductor substrate and self-aligned with said gate stack; and a counter doped region embedded in said super-steep retrograde island, wherein said counter doped region has a doping type opposite to a doping type of said super-steep retrograde island. The semiconductor structures and the methods for manufacturing the same facilitate alleviating short channel effects.
US08809951B2 Chip packages having dual DMOS devices with power management integrated circuits
Chip packages having power management integrated circuits are described. Power management integrated circuits can be combined with on-chip passive devices, and can provide voltage regulation, voltage conversion, dynamic voltage scaling, and battery management or charging. The on-chip passive devices can include inductors, capacitors, or resistors. Power management using a built-in voltage regulator or converter can provide for immediate adjustment of the voltage range to that which is needed. This improvement allows for easier control of electrical devices of different working voltages and decreases response time of electrical devices. Related fabrication techniques are described.
US08809947B1 Integrated circuits and methods for fabricating integrated circuits with cladded non-planar transistor structures
In an exemplary embodiment, a method for fabricating integrated circuits includes providing a semiconductor substrate. The method etches the semiconductor substrate to form a non-planar transistor structure having sidewalls. On a standard (100) <110> substrate the fin sidewalls have (110) surface plane if the fins are aligned or perpendicular with the <110> wafer notch. The method includes depositing a sacrificial liner along the sidewalls of the non-planar transistor structure. Further, a confining material is deposited overlying the semiconductor substrate and adjacent the sacrificial liner. The method includes removing at least a portion of the sacrificial liner and forming a void between the sidewalls of the non-planar transistor structure and the confining material. A cladding layer is epitaxially grown in the void. Since the sidewall growth is limited by the confining material, a cladding layer of uniform thickness is enabled on fins with (110) sidewall and (100) top surface.
US08809946B2 Wide trench termination structure for semiconductor device
A wide trench termination structure for semiconductor device includes a wide trench structure defined on a semiconductor substrate and having a width larger than that of narrow trench structures on an active region of the semiconductor device, an oxide layer arranged on an inner face of the wide trench structure, at least one trench polysilicon layer arranged on the oxide layer and on inner sidewall of the wide trench structure, a metal layer arranged on the oxide layer not covered by the trench polysilicon layer and on the trench polysilicon layer, and a field oxide layer arranged on the semiconductor substrate and outside the wide trench structure.
US08809945B2 Semiconductor device having angled trench walls
A MOSFET includes: a substrate provided with a trench having a side wall surface having an off angle of not less than 50° and not more than 65° relative to a {0001} plane; an oxide film; and a gate electrode. The substrate includes a source region, a body region, and a drift region formed to sandwich the body region between the source region and the drift region. The source region and the body region are formed by means of ion implantation. The body region has an internal region sandwiched between the source region and the drift region and having a thickness of 1 μm or smaller in a direction perpendicular to a main surface thereof. The body region has an impurity concentration of 3×1017 cm−3 or greater.
US08809943B2 Three dimensional semiconductor memory devices and methods of fabricating the same
A three dimensional semiconductor memory device includes an electrode structure having a plurality of conductive electrode patterns and insulating patterns alternatingly stacked on a substrate. Opposite sidewalls of the electrode structure include respective grooves therein extending in a direction substantially perpendicular to the substrate. First and second active patterns protrude from the substrate and extend within the grooves in the opposite sidewalls of the electrode structure, respectively. Respective data storing layers extend in the grooves between the conductive electrode patterns of the electrode structure and sidewalls of the first and second active patterns adjacent thereto. Related fabrication methods are also discussed.
US08809942B2 Semiconductor device having trench structure
According to an embodiment, a trench structure and a second semiconductor layer are provided in a semiconductor device. In the trench structure, a trench is provided in a surface of a device termination portion with a first semiconductor layer of a first conductive type including a device portion and the device termination portion, and an insulator is buried in the trench in such a manner to cover the trench. The second semiconductor layer, which is of a second conductive type, is provided on the surface of the first semiconductor layer, is in contact with at least a side on the device portion of the trench, and has a smaller depth than the trench. The insulator and a top passivation film for the semiconductor device are made of the same material.
US08809941B2 Semiconductor device and method for fabricating the same
A semiconductor device includes a semiconductor substrate having an active region defined by a device isolation structure. A recessed channel is formed on the semiconductor substrate under the active region. A recessed junction region is formed between the recessed channel and the device isolation structure adjacent to the recessed channel.
US08809933B2 Bit line structure, semiconductor device and method of forming the same
A semiconductor device including a substrate, a plurality of stacked gate structures, a plurality of doped regions, a plurality of liner layers, a plurality of conductive layers, a plurality of dielectric layers and a plurality of word lines is provided. The substrate has a plurality of trenches therein. The stacked gate structures are on the substrate between the trenches. The doped regions are in the substrate at sidewalls or bottoms of the trenches. The liner layers are on at least a portion of sidewalls of the stacked gate structures and on sidewalls of the trenches. The conductive layers are in the trenches and electrically connected to the doped regions. The dielectric layers are on the conductive layers and between the stacked gate structures. The word lines are on the substrate and electrically connected to the stacked gate structures.
US08809927B2 Semiconductor memory device
A highly integrated DRAM is provided. A circuit for driving a memory cell array is formed over a substrate, a bit line is formed thereover, and a semiconductor region, word lines, and a capacitor are formed over the bit line. Since the bit line is located below the semiconductor region, and the word lines and the capacitor are located above the semiconductor region, the degree of freedom of the arrangement of the bit line is high. When an open-bit-line DRAM is formed, an area per memory cell less than or equal to 6F2, or when a special structure is employed for a cell transistor, an area per memory cell less than or equal to 4F2 can be achieved.
US08809926B2 Semiconductor memory devices including vertical transistor structures
A semiconductor memory device may include a common source region on a substrate, an active pattern between the substrate and the common source region, a gate pattern facing a sidewall of the active pattern, a gate dielectric pattern between the gate pattern and the active pattern, a variable resistance pattern between the common source region and the active pattern, and an interconnection line.
US08809924B2 Imaging device, method for fabricating imaging device, and imaging apparatus
According to an aspect of the invention, an imaging device includes a plurality of photoelectric conversion elements and a read-out portion. The photoelectric conversion elements are arranged above a substrate. The read-out portion reads out signal corresponding to charges which are generated from each of the photoelectric conversion elements. Each of the photoelectric conversion elements includes a first electrode that collects the charge, a second electrode that is disposed opposite to the first electrode, a photoelectric conversion layer that generates the charges and disposed between the first electrode and the second electrode, and an electron blocking layer that is disposed between the first electrode and the photoelectric conversion layer. Distance between the first electrodes of adjacent photoelectric conversion elements is 250 nm or smaller. Each of the electron blocking layers has a change in surface potential of −1 to 3 eV from a first face to a second face.
US08809921B2 Solid-state imaging apparatus, method of manufacturing same, and electronic apparatus
A solid-state imaging apparatus includes a plurality of pixels each including a photoelectric conversion unit and pixel transistors, which are formed on a semiconductor substrate; a floating diffusion unit in the pixel; a first-conductivity-type ion implantation area for surface pinning, which is formed over the surface on the side of the photoelectric conversion unit and the surface of the semiconductor substrate; and a second-conductivity-type ion implantation area for forming an overflow path serving as an overflow path for the floating diffusion unit, the second-conductivity-type ion implantation area being formed below the entire area of the first-conductivity-type ion implantation area. An overflow barrier is formed using the second-conductivity-type ion implantation area. A charge storage area is formed using an area in which the second-conductivity-type semiconductor area and the second-conductivity-type ion implantation area superpose each other.
US08809920B2 Prevention of fin erosion for semiconductor devices
A dielectric metal compound liner can be deposited on a semiconductor fin prior to formation of a disposable gate structure. The dielectric metal compound liner protects the semiconductor fin during the pattering of the disposable gate structure and a gate spacer. The dielectric metal compound liner can be removed prior to formation of source and drain regions and a replacement gate structure. Alternately, a dielectric metal compound liner can be deposited on a semiconductor fin and a gate stack, and can be removed after formation of a gate spacer. Further, a dielectric metal compound liner can be deposited on a semiconductor fin and a disposable gate structure, and can be removed after formation of a gate spacer and removal of the disposable gate structure. The dielectric metal compound liner can protect the semiconductor fin during formation of the gate spacer in each embodiment.
US08809918B2 MOSFETs with multiple dislocation planes
A method includes forming a metal-oxide-semiconductor field-effect transistor (MOSFET), which includes forming a first dislocation plane adjacent to a gate electrode of the MOSFET, and forming a second dislocation plane adjacent to the gate electrode of the MOSFET. The first and the second dislocation planes are on a same side of the gate electrode, and extend into source/drain regions of the MOSFET.
US08809917B2 Memory elements and cross point switches and arrays of same using nonvolatile nanotube blocks
Under one aspect, a covered nanotube switch includes: (a) a nanotube element including an unaligned plurality of nanotubes, the nanotube element having a top surface, a bottom surface, and side surfaces; (b) first and second terminals in contact with the nanotube element, wherein the first terminal is disposed on and substantially covers the entire top surface of the nanotube element, and wherein the second terminal contacts at least a portion of the bottom surface of the nanotube element; and (c) control circuitry capable of applying electrical stimulus to the first and second terminals. The nanotube element can switch between a plurality of electronic states in response to a corresponding plurality of electrical stimuli applied by the control circuitry to the first and second terminals. For each different electronic state, the nanotube element provides an electrical pathway of different resistance between the first and second terminals.
US08809915B2 Gate conductor with a diffusion barrier
A gate conductor structure is provided having a barrier region between a N-type device and a P-type device, wherein the barrier region minimizes or eliminates cross-diffusion of dopant species across the barrier region. The barrier region comprises at least one sublithographic gap in the gate conductor structure. The sublithographic gap is formed by using self-assembling copolymers to form a sublithographic patterned mask over the gate conductor structure. According to one embodiment, at least one sublithographic gap is a slit or line that traverses the width of the gate conductor structure. The sublithographic gap is sufficiently deep to minimize or prevent cross-diffusion of the implanted dopant from the upper portion of the gate conductor. According to another embodiment, the sublithographic gaps are of sufficient density that cross-diffusion of dopants is reduced or eliminated during an activation anneal such that changes in Vt are minimized.
US08809908B2 Semiconductor wafer, semiconductor wafer manufacturing method, and electronic device
A high-quality GaAs-type crystal thin film using an inexpensive Si wafer with good thermal release characteristics is achieved. Provided is a semiconductor wafer comprising an Si wafer; a Ge layer that is crystal-grown on the wafer and shaped as an isolated island; a buffer layer that is crystal-grown on the Ge layer and is a group 3-5 compound semiconductor layer containing P; and a functional layer that is crystal-grown on the buffer layer. The Ge layer may be shaped as an island having a size that does not exceed double a distance moved by crystal defects as a result of annealing the Ge layer at a certain temperature for a certain time. The Ge layer may be shaped as an island having a size for which stress due to a difference relative to a thermal expansion coefficient of Si, which is material of the wafer, does not cause crystal defects when the Ge layer is annealed at a certain temperature.
US08809906B2 Semiconductor optical device
A semiconductor optical device includes a first clad layer, a second clad layer and an optical waveguide layer sandwiched between the first clad layer and the second clad layer, wherein the optical waveguide layer includes a first semiconductor layer, a second semiconductor layer disposed on the first semiconductor layer and extending in one direction, and a third semiconductor layer covering a top surface of the second semiconductor layer, and wherein the first semiconductor layer includes an n-type region disposed on one side of the second semiconductor layer, a p-type region disposed on the other side of the second semiconductor layer, and an i-type region disposed between the n-type region and the p-type region, and wherein the second semiconductor layer has a band gap narrower than band gaps of the first semiconductor layer and the third semiconductor layer.
US08809902B2 Power semiconductor diode, IGBT, and method for manufacturing thereof
A power semiconductor diode is provided. The power semiconductor diode includes a semiconductor substrate having a first emitter region of a first conductivity type, a second emitter region of a second conductivity type, and a drift region of the first conductivity type arranged between the first emitter region and the second emitter region. The drift region forms a pn-junction with the second emitter region. A first emitter metallization is in contact with the first emitter region. The first emitter region includes a first doping region of the first conductivity type and a second doping region of the first conductivity type. The first doping region forms an ohmic contact with the first emitter metallization, and the second doping region forms a non-ohmic contact with the first emitter metallization. A second emitter metallization is in contact with the second emitter region.
US08809901B2 Nanowire light emitting device and method of manufacturing the same
The invention provides a nanowire light emitting device and a manufacturing method thereof. In the light emitting device, first and second conductivity type clad layers are formed and an active layer is interposed therebetween. At least one of the first and second conductivity type clad layers and the active layer is a semiconductor nanowire layer obtained by preparing a layer of a mixture composed of a semiconductor nanowire and an organic binder and removing the organic binder therefrom.
US08809897B2 Solid state transducer devices, including devices having integrated electrostatic discharge protection, and associated systems and methods
Solid state transducer devices having integrated electrostatic discharge protection and associated systems and methods are disclosed herein. In one embodiment, a solid state transducer device includes a solid state emitter, and an electrostatic discharge device carried by the solid state emitter. In some embodiments, the electrostatic discharge device and the solid state emitter share a common first contact and a common second contact. In further embodiments, the solid state lighting device and the electrostatic discharge device share a common epitaxial substrate. In still further embodiments, the electrostatic discharge device is positioned between the solid state lighting device and a support substrate.
US08809895B2 Light emitting device and method of fabricating the same
Provided are a light emitting device and a method of fabricating the same. The light emitting device includes a first conductive type semiconductor layer, a second conductive type semiconductor layer, and an active layer between the first conductive type semiconductor layer and the second conductive type semiconductor layer, the active layer being formed of a semiconductor material. Also, the light emitting device further includes a current spreading layer comprising a plurality of carbon nanotube bundles physically connected to each other on one of the first and second conductive type semiconductor layers.
US08809894B2 Semiconductor light emitting diode and method of producing the same
A semiconductor light emitting diode including: a support substrate; an intermediate layer including an intermediate electrode portion, a second conductive semiconductor layer, an active layer, a first conductive semiconductor layer and an upper electrode portion sequentially disposed on the upper surface side of the support substrate in this order; and a lower electrode layer provided on the lower surface side of the support substrate, where: the intermediate layer has at least one intermediate electrode portion extending linearly or in an island-like shape; and the upper electrode portion and the intermediate electrode portion are disposed in such a positional relationship that these electrode portions are in parallel with and offset from each other and a distance between the upper electrode portion and the intermediate electrode portion is within the range of 10 μm to 50 μm.
US08809892B2 Light emitting diode and method of fabricating the same
The present invention relates to a light emitting diode and a method of fabricating the same, wherein the distance between a fluorescent substance and a light emitting diode chip is uniformly maintained to enhance luminous efficiency. To this end, there is provided a light emitting diode comprising at least one light emitting diode chip, lead terminals for use in applying electric power to the light emitting diode chip, and a frame that is used for mounting the light emitting diode chip thereon and is formed to have a predetermined height and a shape corresponding to that of the light emitting diode chip.
US08809888B2 Light emitting element with improved light extraction efficiency, light emitting device comprising the same, and fabricating method of the light emitting element and the light emitting device
Provided is a light emitting element, a light emitting device including the same, and fabrication methods of the light emitting element and light emitting device. The light emitting device comprises a substrate, a light emitting structure including a first conductive layer of a first conductivity type, a light emitting layer, and a second conductive layer of a second conductivity type which are sequentially stacked, a first electrode which is electrically connected with the first conductive layer; and a second electrode which is electrically connected with the second conductive layer and separated apart from the first electrode, wherein at least a part of the second electrode is connected from a top of the light emitting structure, through a sidewall of the light emitting structure, and to a sidewall of the substrate.
US08809884B2 Light emitting device including an electrode on a textured surface, light emitting device package and lighting system
Disclosed are a light emitting device, a light emitting device package and a lighting system. The light emitting device of the embodiment includes a light emitting structure including a first conductive semiconductor layer, a second conductive semiconductor layer and an active layer between the first and second conductive semiconductor layers; a second electrode under the second conductive semiconductor layer; a first texture over a first region of the first conductive semiconductor layer; an A-electrode over the first region of the first conductive semiconductor layer; and a B-electrode over a second region of the first conductive semiconductor layer, wherein the B-electrode includes a pad electrode connected to a wire.
US08809883B2 LED lamp
A LED lamp is disclosed which has a plurality of light unit, each of the light unit has at least one flat metal lead for heat dissipation and the lower part of the metal lead is mounted on a heat sink for a further heat dissipation.
US08809879B2 Light-emitting device and a method of manufacturing light-emitting device
To provide a highly reliable light-emitting device and especially a light-emitting device which can be formed without use of a metal mask and includes a plurality of light-emitting elements. A structural body at least an end of which has an acute-angled shape is provided so that the end can pass downward through an electrically conductive film formed over the insulating layer and can be at least in contact with an insulating layer having elasticity, thereby physically separating the electrically conductive film, and the electrically conductive films are thus electrically insulated from each other. Such a structure may be provided between adjacent light-emitting elements so that the light-emitting elements can be electrically insulated from each other in the light-emitting device.
US08809870B2 Semiconductor device
A conventional DRAM needs to be refreshed at an interval of several tens of milliseconds to hold data, which results in large power consumption. In addition, a transistor therein is frequently turned on and off; thus, deterioration of the transistor is also a problem. These problems become significant as the memory capacity increases and transistor miniaturization advances. Another problem is that an increase in memory capacity leads to an increase in the area, despite an attempt at integration through advancement of transistor miniaturization. A transistor is provided which includes an oxide semiconductor and has a trench structure including a trench for a gate electrode and a trench for element isolation. In addition, a plurality of memory elements each including the transistor having a trench structure and including an oxide semiconductor is stacked in a semiconductor device, whereby the circuit area of the semiconductor device can be reduced.
US08809868B2 Group-III nitride semiconductor device, method for fabricating Group-III nitride semiconductor device, and epitaxial substrate
Provided is a Group III nitride semiconductor device, which comprises an electrically conductive substrate including a primary surface comprised of a first gallium nitride based semiconductor, and a Group III nitride semiconductor region including a first p-type gallium nitride based semiconductor layer and provided on the primary surface. The primary surface of the substrate is inclined at an angle in the range of not less than 50 degrees, and less than 130 degrees from a plane perpendicular to a reference axis extending along the c-axis of the first gallium nitride based semiconductor, an oxygen concentration Noxg of the first p-type gallium nitride based semiconductor layer is not more than 5×1017 cm−3, and a ratio (Noxg/Npd) of the oxygen concentration Noxg to a p-type dopant concentration Npd of the first p-type gallium nitride based semiconductor layer is not more than 1/10.
US08809866B2 Light emitting device and electronic apparatus
An organic EL device as a light emitting device includes: a first light emitting element that is disposed on a first surface of a substrate and that has a first pixel electrode; a second light emitting element that has a second pixel electrode; and an insulating layer that is provided with a first opening which exposes the first pixel electrode and a second opening which exposes the second pixel electrode. Further, in the organic EL device, the first opening is configured so that the insulating layer covers equal to or more than 50% of the circumferential edge portion of the first pixel electrode, and the second opening is configured so that the insulating layer covers less than 50% of the circumferential edge portion of the second pixel electrode.
US08809865B2 Display device
A display device including a base substrate, a pixel disposed on the base substrate, and a color filter part disposed between the base substrate and the pixel. The color filter part includes a color filter corresponding to the pixel and a black matrix disposed at at least a side of the color filter. The pixel includes a cover layer defining a tunnel-shaped cavity on the base substrate, an image display part disposed in the tunnel-shaped cavity, and first and second pixel electrodes and a common electrode applying an electric field to the image display part. The tunnel-shaped cavity is formed by forming a sacrificial layer and wet-etching the sacrificial layer.
US08809863B2 Thin-film transistor array substrate, organic light-emitting display having the same, and method of manufacturing the organic light-emitting display
A thin-film transistor array substrate, an organic light-emitting display having the same, and a method of manufacturing the organic light-emitting display are disclosed. In one embodiment, the thin-film transistor array substrate includes a buffer layer formed on a substrate, a first insulating layer formed on the buffer layer, a pixel electrode formed on the first insulating layer using a transparent conductive material, an intermediate layer that covers an upper side and outer side-surfaces of the pixel electrode and includes a organic light-emitting layer, a gap formed by etching the first insulating layer and the buffer layer at a peripheral of the pixel electrode, and a facing electrode that is formed on an upper side and outer side-surfaces of the pixel electrode to cover the intermediate layer and the gap.
US08809860B2 III-V compound semiconductor material passivation with crystalline interlayer
The present disclosure reduces and, in some instances, eliminates the density of interface states in III-V compound semiconductor materials by providing a thin crystalline interlayer onto an upper surface of a single crystal III-V compound semiconductor material layer to protect the crystallinity of the single crystal III-V compound semiconductor material layer's surface atoms prior to further processing of the structure.
US08809857B2 Thin film transistor comprising oxide semiconductor
Provided are a thin film transistor in which an oxide semiconductor combined with a nitride containing boron or aluminum is applied to a channel layer and a method of fabricating the same. The thin film transistor in which an oxide semiconductor combined with a nitride containing boron or aluminum is applied to a channel layer exhibits significantly improved mobility and increased stability at a high temperature.
US08809850B2 Semiconductor device having switching transistor that includes oxide semiconductor material
One object is to provide a new semiconductor device whose standby power is sufficiently reduced. The semiconductor device includes a first power supply terminal, a second power supply terminal, a switching transistor using an oxide semiconductor material and an integrated circuit. The first power supply terminal is electrically connected to one of a source terminal and a drain terminal of the switching transistor. The other of the source terminal and the drain terminal of the switching transistor is electrically connected to one terminal of the integrated circuit. The other terminal of the integrated circuit is electrically connected to the second power supply terminal.
US08809847B2 Photoelectric conversion device and imaging device
A photoelectric conversion device includes an organic photoelectric conversion layer, and suppresses sensitivity degradation caused by the light irradiation. A photoelectric conversion device 100 is formed by stacking a first electrode layer 104, a photoelectric conversion layer 15 including an organic material, and a second electrode layer 108 on a substrate 101, in which the photoelectric conversion layer 15 has a bulk hetero structure of a P-type organic semiconductor and an N-type organic semiconductor, and a difference between an ionization potential of the P-type organic semiconductor and an apparent ionization potential of the bulk hetero structure is 0.50 eV or less. Accordingly, it is possible to suppress sensitivity degradation caused by the light irradiation.
US08809843B2 Nickel-based electrocatalytic photoelectrodes
A photoelectrode, methods of making and using, including systems for water-splitting are provided. The photoelectrode can be a semiconductive material having a photocatalyst such as nickel or nickel-molybdenum coated on the material.
US08809840B2 Organic light emitting device
An organic light emitting device may include an emission layer between a reflecting electrode and one of a transmitting or transflective electrode, and an optical control layer formed with an organic material that is 5000 to 10,000 Å thick between the transmitting or transflective electrode and the emission layer.
US08809839B2 Organic semiconductor polymer, transistor including an organic semiconductor polymer and methods of fabricating the same
An organic semiconductor polymer, a transistor including an organic semiconductor polymer and methods of fabricating the same are provided, the organic semiconductor polymer including an aromatic or heteroaromatic main chain and at least one of a fluoro or a perfluoroalkyl at a polymer terminal end.
US08809834B2 Photodetector capable of detecting long wavelength radiation
Apparatuses capable of and techniques for detecting long wavelength radiation are provided.
US08809832B1 Method of selective photo-enhanced wet oxidation for nitride layer regrowth on substrates and associated structure
Various embodiments of the present disclosure pertain to selective photo-enhanced wet oxidation for nitride layer regrowth on substrates. In one aspect, a method may comprise: forming a first III-nitride layer with a first low bandgap energy on a first surface of a substrate; forming a second III-nitride layer with a first high bandgap energy on the first III-nitride layer; transforming portions of the first III-nitride layer into a plurality of III-oxide stripes by photo-enhanced wet oxidation; forming a plurality of III-nitride nanowires with a second low bandgap energy on the second III-nitride layer between the III-oxide stripes; and selectively transforming at least some of the III-nitride nanowires into III-oxide nanowires by selective photo-enhanced oxidation.
US08809831B2 On/off ratio for non-volatile memory device and method
A switching device includes a first dielectric material formed overlying a substrate. A bottom wiring material and a switching material are sequentially formed overlying the first dielectric material. The bottom wiring material and the switching material are patterned and etched to form a first structure having a top surface region and a side region. The first structure includes a bottom wiring structure and a switching element having the top surface region including an exposed region. A second dielectric material is formed overlying the first structure. A first opening region is formed in a portion of the second dielectric layer to expose a portion of the top surface region. A dielectric side wall structure is formed overlying a side region of the first opening region. A top wiring material including a conductive material is formed overlying the top surface region to be directly contact with the switching element.
US08809828B2 Small footprint phase change memory cell
An example embodiment disclosed is a phase change memory cell in a semiconductor wafer. The semiconductor wafer includes a first metalization layer (Metal 1). The phase change memory cell includes an insulating substrate defining a non-sublithographic via. The non-sublithographic via is located on the first metalization layer and includes a bottom and a sidewall. Intermediate insulating material is positioned below the insulating substrate. The intermediate insulating material defines a sublithographic aperture passing through the bottom of the non-sublithographic via. A bottom electrode is positioned within the sublithographic aperture, and is composed of conductive non-phase change material. The non-sublithographic via includes phase change material positioned within. The phase change material is electrically coupled to the bottom electrode. A liner is positioned along the sidewall of the non-sublithographic via. The liner is electrically coupled to the phase change material and is composed of the conductive non-phase change material.
US08809827B1 Thermally assisted MRAM with multilayer strap and top contact for low thermal conductivity
A mechanism is provided for a thermally assisted magnetoresistive random access memory device (TAS-MRAM). The device includes a magnetic tunnel junction configured to store data, a first multilayer contact structure positioned on one end of the magnetic tunnel junction, and a second multilayer contact structure positioned on an opposite end of the magnetic tunnel junction. The first multilayer contact structure and the second multilayer contact structure each include multiple layers of metals. The multiple layers of metals are structured to inhibit thermal conductivity between the magnetic tunnel junction and surrounding structures, and the multiple layers of metals are structured to electrically conduct electrical current.
US08809823B1 System and method for controlling droplet timing and steering in an LPP EUV light source
A method and apparatus for improved control of the trajectory and timing of droplets of target material in a laser produced plasma (LPP) extreme ultraviolet (EUV) light system is disclosed. A droplet illumination module generates a laser curtain, and sensors detect the droplets as they pass through the curtain. One sensor in combination with a controller detects the position of the droplets relative to a desired trajectory to the irradiation site so that a signal can be sent to an actuator of a droplet generator to adjust orientation of the droplet generator and direct subsequent droplets to the irradiation site, as in the prior art. A second sensor, or droplet detection module, also detects each droplet as it passes through the curtain, and in combination with a controller determines when the source laser should generate a pulse so that the pulse will arrive at the irradiation site at the same time as the droplet, and sends a signal to the source laser to fire at the correct time.
US08809819B2 Target supply unit and extreme ultraviolet light generation apparatus
A target supply unit may include: a target storage unit for storing a target material thereinside; a target output unit having a through-hole formed therein, through which the target material stored inside the target storage unit is outputted; an electrode having a through-hole formed therein arranged to face the target output unit, the electrode being coated with an electrically conductive material at least on a part of a surface facing the target output unit; and a voltage generator for applying a voltage between the target material and the electrode.
US08809816B2 Multipurpose device for transmitting radiation from a source to an object
A multipurpose device for transmitting radiation from a source to an object comprises two antennas, each designed as a truncated segment of a spherical or cylindrical surface, a radiation source provided in the aperture plane of one of the antennas, and an object placed in the combined focal area of the two antennas. The antennas are positioned opposite one another at a distance of from 0.6 to double the radius of the spherical or cylindrical surface, and the radiation source is of a distributed type. The antenna design effectively concentrates radiation emitted by a distributed source on an object placed in the focal area of the antenna, providing greater efficiency of radiation transmission, the possibility of radiation power variation, a more uniform concentration of radiation, an increase in the volume of the focal area without replacing the radiation source, increased reliability of the system, and reduced power requirements.
US08809814B2 Irradiation or irradiation planning system for a rescanning method using a particle beam
A method for irradiating a target volume includes defining a target region having a plurality of target points. The target points are individually approachable. The method includes defining a number of rescanning passes, in which the target region is scanned multiple times, such that the plurality of target points of the target region is approached variously often during the rescanning passes. At least some target points of the plurality of target points are not approached in all of the rescanning passes. The approaching of the plurality of target points is distributed among the rescanning passes such that for a target point of the plurality of target points that is not approached in all of the rescanning passes, at least one further rescanning pass, in which the target point is not approached, is located before a final rescanning pass, in which the target point is approached.
US08809808B2 Stimulated emission-based optical detection system
The present invention provides an optical detection system comprising an illumination unit and a detection unit. The illumination unit comprises two laser beams of two different wavelengths. One beam is used to excite targeted molecules in a sample to their excited states. The other beam is used to induce the excited molecules in the sample to generate a stimulated emission signal. The stimulated emission signal can be used for long-distance detection due to its coherent property. Its extraction from the detection unit can be realized by demodulating the second beam's intensity change.
US08809806B1 Portable sterilization assembly
A portable sterilization assembly includes a housing that has a bottom wall and a perimeter wall that is attached to and extends upwardly from the bottom wall. A container has an upper wall, a lower wall, and an exterior wall extending between the upper and lower walls. The exterior wall is adjoined to the perimeter wall and the bottom and lower walls are co-planar with each other. The upper wall has a pump aperture extending therethrough. A pump is mounted on the housing and extends through the pump aperture to be in fluid communication with an interior of the container. An ultraviolet light is mounted within the housing. An actuator mounted on the housing is electrically coupled to the ultraviolet light. The housing may have eating utensils inserted inside and the actuator actuated such that the ultraviolet light directs ultraviolet light into the housing to sterilize the eating utensils.
US08809805B2 Radiation shield lid for self-aligning radioisotope elution system
A radiation shield lid for shielding a radioisotope generator. The radiation shield lid includes an alignment structure configured to align the shield lid to a radioisotope generator.
US08809804B2 Holder and tool for radioisotope elution system
A holder for a vial containing a sterile liquid for use with a radiopharmaceutical elution system includes a holder body. The body has a top, an opposing bottom, an opening in the top and a vial chamber. The vial chamber extends from the opening in the top toward the bottom and is sized and shaped for receiving the vial therein. An access opening extends through the bottom to the vial chamber and is aligned with a septum of the elution vial when the sterile vial is received in the vial chamber. A cap is removably secured to the top of the holder body for selectively opening and closing the vial chamber. The holder body includes plastic and has a density less than the density of the cap.
US08809803B2 Inductively coupled plasma ion source with multiple antennas for wide ion beam
A wide ion beam source includes a plurality of RF windows arranged in a predetermined relationship, a single plasma chamber disposed on a first side of the plurality of RF windows, a plurality of RF antennas, each RF antenna of the plurality of RF antennas disposed on a second side of a respective RF window of the plurality of RF windows, the second side being opposite the first side, and a plurality of RF sources, each RF source coupled to a respective RF antenna of the plurality of RF antennas, wherein a difference in frequency of a first RF signal produced by a first RF source coupled to a first RF antenna from that of a second RF signal produced by a second RF source coupled to an RF antenna adjacent to the first RF antenna is greater than 10 kHz.
US08809802B2 Portable ion generator
An ion generator is disclosed. The ion generator has improved portability and ion generation efficiency. As is apparent from the above description, the ion generator according to the present invention is configured so that the discharge unit is constituted by the felts, and the piezoelectric element, not the coil type transformer, is used in the high voltage generation unit which generates high voltage. Consequently, the present invention has the effect of improving portability of the ion generator and the present invention has the effect of improving ion generation efficiency although the portability of the ion generator is improved by configuring the ion generator according to the present invention so that the discharge unit is constituted by the felts, and the piezoelectric element, not the coil type transformer, is used in the high voltage generation unit which generates high voltage.
US08809800B2 Ion source and a method for in-situ cleaning thereof
An ion source and method of cleaning are disclosed. One or more heating units are placed in close proximity to the inner volume of the ion source, so as to affect the temperature within the ion source. In one embodiment, one or more walls of the ion source have recesses into which heating units are inserted. In another embodiment, one or more walls of the ion source are constructed of a conducting circuit and an insulating layer. By utilizing heating units near the ion source, it is possible to develop new methods of cleaning the ion source. Cleaning gas is flowed into the ion source, where it is ionized, either by the cathode, as in normal operating mode, or by the heat generated by the heating units. The cleaning gas is able to remove residue from the walls of the ion source more effectively due to the elevated temperature.
US08809799B2 Charged particles beam apparatus and charged particles beam apparatus design method
Problems to be solved: To obtain higher brightness than Langmuir limit. Adjust brightness to the optimum value.Method of resolution: To obtain such beams, the following means and methods are effective. A charged particles beam apparatus consisting of a charged particle source, a beam drawing electrode, and a beam control electrode, wherein; after the charged particles beam source a condenser lens is designed, and brightness of the charged particles beam is adjusted by adjusting a magnification factor of said condenser lens.
US08809798B2 Methods to enhance nuclear spectroscopy analysis
Methods, systems and devices for estimating a parameter of interest from a gamma ray spectrum relating to a volume of matter using standard gamma ray spectra from reference samples, wherein there is at least one non-elemental characteristic that is different between the volume and at least one of the reference samples, wherein the non-elemental characteristic difference affects gamma ray interactions. Methods may include deconvolving a gamma ray spectrum obtained from the analysis volume into a plurality of elemental spectral yields, wherein deconvolution includes compensating for effects of the non-elemental characteristic difference. Methods may include using at least one compensation standard spectrum configured to compensate for the effects of the non-elemental characteristic of the at least one of the reference samples.
US08809796B2 Lag compensating X-ray detector and method of driving the same
An X-ray detector and a method of driving the X-ray detector, which accurately compensate for an image lag of an X-ray scanning by using an X-ray image and a dark image, are provided. A stand-by time for the X-ray scanning may be reduced by increasing the accuracy of the image lag compensation.
US08809794B2 Radiation detector
A radiation detector comprises a scintillator 2A having a first end face 11, a second end face 13 disposed on a side opposite from the first end face 11, and a plurality of light-scattering surfaces 21 formed with an interval therebetween along a first direction P from the first end face 11 side to the second end face 13 side; a first photodetector 12 optically coupled to the first end face 11; and a second photodetector 14 optically coupled to the second end face 13. The light-scattering surfaces 21 are formed so as to intersect the first direction P. The light-scattering surfaces 21 include modified regions 21R formed by irradiating the inside of the scintillator 2A with laser light.
US08809789B2 Infrared sensor and air conditioner
In an infrared sensor 1 including a condenser lens 3 and a multi-element light-receiving unit 2 with a plurality of light-receiving elements 2a to 2h aligned therein on a straight line, a position of receiving an intensity distribution peak of infrared rays which have passed through the condenser lens 3 is deviated from the center position of the multi-element light-receiving unit 2 to a desired light-receiving element position. Especially when the infrared sensor 1 is included in an air conditioner, the position of receiving the intensity distribution peak of the infrared rays is set to the position of a light-receiving element used for detecting heat in a location far from the installment position of the air conditioner.
US08809787B2 Gunshot detection system and method
A device and a method for use in detection of a muzzle flash event is described. The device can include a Photo Detector Array (PDA), sensitive in at least a portion of the NIR and SWIR spectrum, and a filter of electromagnetic radiation selectively passing in this portion a spectral range of low atmospheric transmission, the PDA has an integration time shorter than a duration of the muzzle flash event.
US08809785B2 Pane with optically transparent sensor field
A pane having an optically transparent sensor field including: at least one panel; at least one optically transparent sensor field on the pane; at least one hydrophilic coating applied on the optically transparent sensor field; and at least one encapsulation applied to the optically transparent sensor field and at least one sensor applied in the encapsulation.
US08809781B1 Method of electron beam imaging of a specimen by combining images of an image sequence
A method of imaging of a specimen exposed to an electron beam signal includes acquiring an image sequence of sequential images of the specimen. Each subsequent image in the image sequence represents increased cumulative electron beam signal exposure on the specimen. The method includes collecting cumulative exposure data for each image of the image sequence. The method includes applying a low-pass image processing filter to the images of the image sequence using the cumulative exposure data corresponding to each image to which the filter is being applied to produce processed images. The method includes combining the processed images to produce a final image. A method of imaging is also provided that includes selectively discarding images in the image sequence.
US08809780B2 Electron beam layer manufacturing using scanning electron monitored closed loop control
A process (and apparatus for performing the process) for layer manufacturing a three-dimensional work piece comprising the steps of: feeding raw material in a solid state to a first predetermined location; exposing the raw material to an electron beam to liquefy the raw material; depositing the raw material onto a substrate as a molten pool deposit, the deposit having a forward edge region in an x-y plane with a forward edge region width and a trailing edge region in the x-y plane with a trailing edge region width, under at least one first processing condition; monitoring the molten pool deposit for at least one preselected condition using detecting of scatter from a scanning electron beam contemporaneously with the depositing step; solidifying the molten pool deposit; automatically altering the first processing condition to a different processing condition based upon information obtained from the comparing step; and repeating steps at one or more second locations for building up layer by layer, generally along a z-axis that is orthogonal to the x-y plane, a three-dimensional work piece.
US08809779B2 Method and system for heating substrate in vacuum environment and method and system for identifying defects on substrate
A method for heating a substrate in a vacuum environment and a system therefor is provided. The system includes a chamber capable of holding the substrate located in the vacuum environment and a light source capable of projecting a light beam only on a portion of the substrate. The method includes the following steps. First, the substrate is placed in the vacuumed chamber. Thereafter, the light beam emitted from the light source is projected on the portion of the substrate, such that the portion is significantly heated before whole the substrate is heated. When the light beam is a charged particle beam projected by a charged particle beam assembly and projected on defects located on the substrate, the defects are capable of being identified by an examination result provided by an examination assembly after termination of light beam projection.
US08809773B2 Membrane interface apparatus and method for mass spectrometry
The disclosed method and apparatus couple a membrane interface directly to a mass spectrometer at atmospheric pressure. The membrane may be in capillary or sheet form and allows the introduction of a liquid or gaseous sample to one side of the membrane while the other side of the membrane is bathed with a solution that can easily be used in an atmospheric pressure ionization source. Volatile molecules permeate through a suitable membrane such as poly-dimethyl silicone (PDMS), mix into the appropriate solvent, and are ionized. Because of the rules governing abstracts, this abstract should not be used in construing the claims.
US08809772B2 Systems and methods for using variable mass selection window widths in tandem mass spectrometry
Systems and methods are used to analyze a sample using variable mass selection window widths. A tandem mass spectrometer is instructed to perform at least two fragmentation scans of a sample with different mass selection window widths using a processor. The tandem mass spectrometer includes a mass analyzer that allows variable mass selection window widths. The selection of the different mass selection window widths can be based on one or more properties of sample compounds. The properties may include a sample compound molecular weight distribution that is calculated from a molecular weight distribution of expected compounds or is determined from a list of molecular weights for one or more known compounds. The tandem mass spectrometer can also be instructed to perform an analysis of the sample before instructing the tandem mass spectrometer to perform the at least two fragmentation scans of the sample.
US08809771B2 Devices, systems, and methods for dispersive energy imaging
Devices, systems, and methods for dispersive energy imaging are disclosed. The full three-dimensional velocity distribution function of a flowing particle stream may be measured and properties of the particle stream characterized. In some devices, an aperture system controls the entry of a stream of particles into the sensor where an electrostatic deflector separates the stream of particles into different species, and a detector system senses the separated species.
US08809769B2 Apparatus and method for cross-flow ion mobility spectrometry
A cross-flow ion mobility spectrometer consists of two parallel plates defining a volume between them. Analyte ions flow along an axis from an entrance end to an exit end through the volume. An RF confining field tends to guide ions along the axis. An analytical gas flow is established orthogonal to the axis. A DC electrostatic analytical field is oriented in opposition to the analytical gas flow such that the “drag force” on ions of the selected mobility due to the analytical gas flow is balanced by the force on the ions due to the electrostatic analytical field. The selected ions are thereby able to follow a stable path to the exit end of the cross-flow mobility analyzer. However, the force on ions of other than the selected mobility is unbalanced and these ions are deflected and lost.
US08809768B2 Mass spectrometer with bypass of a fragmentation device
A method for analyzing a mixture of components includes forming precursor ions from the components, alternately causing the precursor ions to pass to and to by-pass a fragmentation device, to form product ions from the precursor ions that pass to the device and to form substantially fewer product ions from precursor ions that by-pass the device, and obtaining mass spectra from product ions received from the device and from precursor ions that by-passed the device. An apparatus for analyzing a sample includes an ion source for forming precursor ions from the components of the sample, a fragmentation device for forming product ions from the precursor ions, a by-pass device disposed upstream of the fragmentation device for switchable by-pass of the fragmentation device, and a mass analyzer.
US08809766B2 Methods and systems for detecting or collecting particles
Methods and systems for detecting and/or collecting particles are disclosed. At least some of the particles are electrically charged by a charger (122). At least some of the charged particles are collected by a collector (140). Information indicating the number of the detected/collected particles based on measured electrical charges of the charged particles is obtained by a processor (170).
US08809765B2 Sensor protector
A sensor protector is intended to reduce the sensitivity of the optical sensor (4) to radiation products which, for example, are formed during sterilization with gamma radiation and to ensure simple and cost-effective manufacture. The sensor protector includes an upper part (1), a lower part (3) and an optical sensor (4). The optical sensor (4) situated on the lower part is positionable in an offset manner with respect to an opening (2) situated in the upper part and movable by means of displacement toward the opening (2) of the upper part (1). The sensor protector is suitable for use in containers and laboratory products that are sterilized by gamma radiation, for example disposable bioreactors.
US08809764B2 Absolute position measuring encoder
An absolute position measuring encoder having an ABS/INC integrated pattern obtained by integrating an absolute pattern and an incremental pattern together is provided. The absolute position measuring encoder includes an imaging optical system (lens) designed to generate an amplitude difference between a light and dark signal derived from the absolute pattern and light and dark signal derived from the incremental pattern, and a signal processing system (comparator) for separating a received light signal from the ABS/INC integrated pattern into an absolute pattern signal and an incremental pattern signal by utilizing the amplitude difference. Accordingly, an absolute pattern signal and an incremental pattern signal can be separated off from the ABS/INC integrated pattern at a high speed with a simple processing circuit.
US08809763B1 Optical position sensor for determining the angular position of a rotating device
An optical position sensor system is disclosed for determining the angular position of a rotary member having a longitudinal rotation axis that extends in an axial direction. The system includes a single light source aligned along the rotation axis. A collimating element is adjacent the light source a predetermined distance, the collimating element aligned along the rotation axis to collimate light from the light source along the rotation axis. A detection element is adjacent the collimating element a predetermined distance to receive collimated light from the collimating element and to provide a linear output. A light blocker is inserted between the collimating element and the detection element, the light blocker coupled to the rotary member to rotate therewith about the rotation axis to block portions of the collimated light from the light source and the collimating element from reaching the detection element in direct relationship to the rotary position of the light blocker.
US08809758B2 Light field image sensor with an angle-sensitive pixel (ASP) device
An angle-sensitive pixel (ASP) device that uses the Talbot effect to detect the local intensity and incident angle of light includes a phase grating disposed above a photodiode assembly or a phase grating disposed above an analyzer grating that is disposed above a photodiode assembly. When illuminated by a plane wave, the upper grating generates a self-image at a selected Talbot depth. Several such structures, tuned to different incident angles, are sufficient to extract local incident angle and intensity. Arrays of such structures are sufficient to localize light sources in three dimensions without any additional optics.
US08809747B2 Current peak spreading schemes for multiplexed heated array
A method of operating a heating plate for a substrate support assembly used to support a semiconductor substrate in a semiconductor processing apparatus, wherein the heating plate comprises power supply lines and power return lines and respective heater zone connected between every pair of power supply line and power return line. The method reduces maximum currents carried by the power supply lines and power return lines by temporally spreading current pulses for powering the heater zones.
US08809744B2 Wax removers for scent warmers and related methods
A wax remover for removing solidified wax within a wax container of a scent-warmer device includes a base having a size and shape configured to fit within a wax container of a scent-warmer device, and at least one tab attached to and extending from the base for removing the base from a wax container of a scented warmer device. Such wax removers are used to remove wax from a wax container of a scent-warmer device. A scent-warmer assembly includes a scent-warmer device that comprises a base housing a heat source, and a wax container configured to be heated by the heat source during operation of the scent-warmer device. The assembly further includes a wax remover disposed within the wax container, and a wax disposed at least partially over the wax remover within the wax container.
US08809743B2 Heater with temperature detecting device, battery structure with heater, and heater unit
There are provided a heater with temperature detecting device capable of accurately detecting the temperature of a laminated sheet heater (the temperature of a heater element) by a temperature detecting device, a battery structure provided with this heater with temperature detecting device, and a heater unit. A first heater with temperature detecting device includes a first laminated sheet heater and a temperature detecting device. In this first heater, a first metal sheet includes a part protruding outward in a lamination direction of a laminated heater to provide at least part of an accommodation space in which the temperature detecting device is accommodated.
US08809742B2 Coated disk having a heatable communication window
A transparent disk that can be electrically heated over a large surface area, comprising: a large-surface-area, electrically conductive, transparent coating, which is applied to a transparent substrate, at least two bus ribbons, which are electrically connected to the electrically conductive transparent coating, at least one locally delimited region free from the coating, wherein at least one heating conductor having two poles is applied inside the free region, and wherein the first pole is electrically connected to the electrically conductive, transparent coating and the second pole is electrically connected to the electrically conductive, transparent coating or a bus ribbon. A method for the production of the disk is also described.
US08809740B2 Two-electrode welding method
In a two-electrode welding method of the present invention, a leading electrode is used to perform gas-shielded arc welding and a trailing electrode is an energized filler. A trailing electrode wire protrudes from a guide lead or guide tip and is energized from an energizing tip. The distance between a welding surface and the energizing tip is 100 mm or more and 1500 mm or less. The distance between electrodes is 10 mm or less. The electric current of the leading electrode is 250 A or more, and the electric current of the trailing electrode is 10 A or more and 50% or less of the electric current of the leading electrode. The feeding speed of the trailing electrode wire is 20% or more and 50% or less of the feeding speed of the leading electrode wire.
US08809737B2 Method, apparatus and software for gas metal arc welding with a continuously fed electrode
A welding method for gas metal arc welding is provided with continuous electrode feeding and control for short arc welding and/or spray arc welding and also short pulsing in which the control cyclically alternates between short pulsing and short arc or spray arc welding, and time for carrying out the respective control being programmed by a user. A welding power source and software for carrying out this method are also provided.
US08809735B2 Consumable electrode arc welding method and consumable electrode arc welding device
If a short circuit does not occur during deceleration of a wire feed speed in forward feed of a welding wire before the wire feed speed reaches a predetermined wire feed speed, a cyclic change is stopped and the wire feed speed is constantly controlled at the first feed speed. If a short circuit occurs during forward feed at the first feed speed, deceleration from the first feed speed starts, and the cyclic change is resumed for welding. This achieves uniform weld bead without increasing spatters even if any external disturbance such as change of distance between a tip and base material occurs.
US08809728B2 Method and apparatus for automatic gas control for a plasma arc torch
A method and apparatus for controlling a gas supply to a plasma arc torch uses a proportional control solenoid valve positioned adjacent the torch to manipulate the gas flow to the torch, thereby extending electrode life during arc transfer and shutdown. Swirl ring design can be simplified and gas supply and distribution systems become less complicated. The invention also allows manipulation of shield gas flow to reduce divot formation when making interior cuts. The system can be controlled with a digital signal processor utilizing a feedback loop from a sensor.
US08809723B2 Insertion element, gas lens with such an insertion element, and welding torch with such a gas lens
For a WIG/TIG welding torch, gas distribution across a cross-section of the gas lens and/or the gas nozzle, is improved and as small a size and as low a weight of the components as possible can be achieved, when an insertion element with a bore in the center through which an electrode is to be guided is arranged, with fan-shaped flow elements being positioned around the bore and twisted relative to the plane of the bore so as to provide for radial deviation of a gas flowing therethrough. The gas lens consists of a base body having a gas distribution channel with at least one gas-lens filter, with an above-described insertion element being arranged in the gas-distribution channel, and with a gas-lens filter, seen in the out-flow direction of the gas, being arranged downstream of the insertion element.
US08809714B2 Switching device and instrument having the same
A manipulation knob is molded from a resin material and is manually depressible by a user. A switch is depressible through the manipulation knob to execute a corresponding switching operation when the manipulation knob is depressed by the user. The manipulation knob includes a resin spring portion, which is molded integrally with the manipulation knob and projects in an axial direction of the manipulation knob. The resin spring portion is resilient and is adapted to exert a resilient reaction force against the switch when the manipulation knob is depressed by the user to depress the switch.
US08809712B2 Switch case with partitioned passages
A switch designed for dustproof performance by minimizing a route of entry of dust from a terminal portion, includes a plurality of terminals, a movable contact piece that is supported in a manner allowing displacement between a non-conduction position and a conduction position, and a contact actuating member that displaces the movable contact piece in response to an externally applied pressing force. A main body of the switch includes an opening communicating with the outside, partition walls formed between the opening and the movable contact piece, barrier walls formed between the opening and the movable contact piece, and passages formed by ends of the barrier walls and walls that are opposite the ends of the barrier walls. Each partition wall extends across the corresponding passage and each terminal includes a connection portion and a blocking portion that is bent from the connection portion and blocks the corresponding passage.
US08809710B2 Actuation unit
The invention relates to an actuation unit of a moving part (1) of a motor vehicle, in particular a rear hood (1), comprising an actuation part (10) that is fastened to a housing part (20), at least two conductor elements (21) disposed on the housing part (20), an elastically deformable contact element (22) that cooperates with the conductor elements (21), a plunger (11), which is disposed at the actuation part (10), for deforming the contact element (22). According to the invention, the actuation part (10) and the housing part (20) delimit an internal space (2) that is totally closed off from the environment (3), and the actuation part (10) is mounted pivotably about an axis (4) that runs axisymetrically with respect to the internal space (2).
US08809707B2 Combination pressure switch with manual shutoff
A combination pressure switch including a pressure switch moveable between open and closed positions in response to a working pressure of a fluid, the pressure switch including a contact assembly having first and second terminals electrically connected through a current-carrying member movable by the pressure switch, and a manual switch configured to move the current-carrying member independent of the movement of the pressure switch.
US08809706B2 Integrating impact switch
An integrating impact switch that can discriminate between accelerations due to different stimuli is provided. Embodiments of the present invention actuate only in response to an acceleration whose magnitude is equal to or greater than an acceleration threshold for a predetermined continuous period of time. Embodiments of the present invention comprise an impact switch having a throw that is operatively coupled with a viscous damper that dampens motion of the throw. As a result, a stimulus that imparts an acceleration that meets or exceeds an acceleration threshold for a time period less than a predetermined time-period threshold does not actuate the switch. A stimulus that imparts an acceleration whose magnitude is equal to or greater than the acceleration threshold for a time period equal to the time-period threshold, however, does actuate the switch.
US08809703B2 Keys with double-diving-board spring mechanisms
Keys may be formed for keyboards. The keyboards may be attached to electronic devices such as computers or may be formed within a portable computer or other electronic equipment. A keyboard may be provided with a planar housing member such as a top plate. The top plate may have openings through which key caps protrude. Each key cap may be attached to a respective spring mechanism. The spring mechanism for each key may have first and second diving-board structures that flex about respective parallel flex axes. A dome switch may be mounted under each spring mechanism. The dome switch is compressed when the key cap is pressed and the first diving-board structure moves towards the dome switch. The top plate may have edge portions surrounding each key opening that form upstop structures that prevent the key caps and spring mechanisms from tilting when the dome switch is compressed.
US08809700B2 Protection part for the electronic circuit of a survey meter, and high range gamma-ray survey meter having same inserted therein
Provided is a protection part for an electronic circuit of a survey meter and a high range gamma-ray survey meter into which the protection part is inserted, in which the protection part is easily mounted in the survey meter to prevent the electronic circuit from being short-circuited when a conductive material is introduced into the electronic circuit. The protection part includes an insulator part for interrupting electricity other than that used for a signal transmission cable, an elastic stainless steel sheet part inserted into the insulator part, and a cable hole part through which the signal transmission cable passes when the protection part is inserted into the high range gamma-ray survey meter. Also, the protection part is inserted into the high range gamma-ray survey meter such that a telescopic part hole and a display part of the high range gamma-ray survey meter are physically separated from each other.
US08809699B2 Junction box and solar cell array
A junction box of a solar cell array/solar module, having a plurality of solar cells connected in multiple strings and including a separate top part mechanically connected to a bottom part, and in one of the bottom and top parts, first contact elements, some being connected in the installed state to solar cells and two of which are connected to a connecting cable of the solar cell array, and in another one of the bottom and top parts, interconnected second contact elements electrically contact first contact elements in the installed state and join them are situated there, and an actuator for releasing the mechanical connection between the bottom and top parts, for completely separating the top and bottom parts and for disconnecting the contact between the first and second contact elements and a control unit assigned to the actuator at the input side for generating an actuator control signal.
US08809698B2 Housing-captured component carrier for reducing fasteners
An electrical control module provides a plastic insert fitting inside a housing and compressed by assembly of the housing lid and base to be held securely therein. Elastic components on the plastic insert are compressed during the assembly provide a secure retention in the face of normal manufacturing tolerances. The plastic insert includes features for attaching electrical components such as electrical contactors, motor starters, disconnect switches, circuit breakers, and overload switches without conventional screw fasteners or the like through channels and elastic detents.
US08809697B2 Passive cooling and EMI shielding system
An electronics enclosure is disclosed that provides passive cooling of electronic components while reducing electromagnetic interference (EMI) emissions. The electronics enclosure includes an electronics assembly with at least one electronic component and a heat sink coupled to the electronics assembly. The heat sink has a base portion configured to thermally couple to the at least one electronic component when the heat sink is coupled to the electronic assembly. The electronics enclosure also includes a conductive enclosure forming an enclosed volume around the electronics assembly. The enclosure has a first opening configured to fit around the heat sink and at least one second opening. All non-conductive passages from the volume to the external environment have at least one cross-sectional opening having a continuous conductive perimeter with a maximum linear length within the opening of less than one quarter wavelength of a determined maximum shielding frequency.
US08809693B2 Three-dimensional circuit board
A three-dimensional circuit board is formed by comprising a board, a first wiring-electrode group provided on a plurality of steps above the board, and a second wiring-electrode connected to the first wiring-electrode group at least in an altitude direction, in which at least a connecting portion between the first wiring-electrode group and the second wiring-electrode is integrated in a continuously identical shape.
US08809691B2 Wired circuit board having first and second conductive patterns with respective connecting portions formed on first and second insulating layers
A wired circuit board includes an insulating layer, and a conductive layer formed on the insulating layer. The insulating layer includes a first insulating layer, and a second insulating layer formed on the first insulating layer. The conductive layer includes a first conductive pattern, and a second conductive pattern. The first conductive pattern includes a first connecting portion formed on the first insulating layer and under the second insulating layer, and at least one pair of first terminals configured continuously to the first connecting portion so as to electrically connect to an external electronic element and spaced apart from each other to allow the electronic element to extend therebetween. The second conductive pattern includes a second connecting portion formed on the second insulating layer, and a second terminal configured continuously to the second connecting portion so as to electrically connect to a magnetic head provided on an external slider.
US08809690B2 Dielectric bond plies for circuits and multilayer circuits, and methods of manufacture thereof
A bond ply, comprising a first outer layer comprising a thermosetting composition and a filler composition; a second outer layer comprising a thermosetting composition and a filler composition that is of the same type as that of the first outer layer; and an intermediate layer disposed between the first and the second outer layers, and comprising a thermosetting composition and a filler composition that is of the same type as the first and second outer layers, wherein the thermosetting composition of the intermediate layer has a degree of cure that is greater than a degree of cure for each of the thermosetting compositions of the first and the second outer layers.
US08809689B2 Systems and methods for composite structures with embedded interconnects
A composite interconnect assembly includes a body structure formed from a composite material (e.g., a carbon graphite material) with one or more conductive traces embedded therein (e.g., a copper or copper alloy). One or more contact regions are provided such that the conductive traces are exposed and are configured to mechanically and electrically connect to one or more electronic components. The body structure may have a variety of shapes, including planar, cylindrical, conical, and the like.
US08809688B2 Polyamic acid solution, polyimide resin and flexible metal clad laminate using the same
Disclosed are a polyamic acid solution, a polyimide resin prepared by imidization of the polyamic acid solution, a flexible metal clad laminate using the polyimide resin, and a printed circuit board including the flexible metal clad laminate, wherein the polyamic acid solution includes (a) 3,3′,4,4′-biphenyltetracarboxylic acid dianhydride (BPDA), and pyromellitic dianhydride (PMDA) as aromatic tetracarboxylic acid dianhydride; (b) at least one aromatic diamine; (c) an organic solvent; and (d) an inorganic filler.
US08809684B2 Insulated wire
There is provided an insulated wire including a wire conductor and an insulation coating formed on the wire conductor by extrusion coating a resin composition. The resin composition is a mixture of a polyphenylene sulfide-based resin (A) and a polyamide-based resin (B), in which a ratio of parts by mass of the resin (B) to that of the resin (A), i.e. (B)/(A), is not less than 5/95 and not more than 30/70.
US08809683B2 Leaky coaxial cable
A leaky coaxial cable includes an inner conductor member extending in axis direction, to propagate signal; an insulator member covering the inner conductor member; a first outer conductor member having conductor wires on circumference surface of the insulator member with shielding density so as to leak a part of the signal to outside thereof; and a plurality of second outer conductor members contacting the first outer conductor member and arranged with constant pitch in the axis direction, to shield the signal; wherein, in the axis direction, each electrical length of the second outer conductor members is the same as electrical length between adjacent second outer conductor members; and the pitch is in range of 1/(1+0.766ν) times to 3/(1+ν) times of propagation wavelength of the signal in the inner conductor member, where ν is wavelength shortening coefficient of the propagation wavelength to free-space wavelength of the signal.
US08809680B2 Grounding bridge
By providing a single housing, component or element incorporating a plurality of passageways or receiving zones formed therein in cooperating association with a mounting ring or clamp constructed for being quickly and easily secured to a clamp, conductor or conduit mounted to an electrical box, junction box, meter box, or similar enclosure, an efficient, easily manufactured and easily assembled bonding bar or grounding bridge is achieved. Preferably, the plurality of passageways/receiving zones are constructed with each passageway or receiving zone cooperatively associated with a locking screw or set screw configured to enable grounding conductors to be inserted through the passageway/receiving zone and securely mounted therein. In this way, grounding conductors from telephones, cable televisions, satellite receivers, radios, television antennas, and the like may be inserted into the passageways/receiving zones and securely mounted in the desired position.
US08809673B2 Stacked photovoltaic cell module
A stacked photovoltaic cell module includes, sequentially stacked, a substrate, a first electrode layer, a first carrier transport layer, a first light absorption layer, a connecting layer with a reflectivity of 10-60%, a second carrier transport layer, a second light absorption layer, and a second electrode layer. The second carrier transport layer has a first refraction index n1 and a first thickness D1, and the second light absorption layer has a second refraction index n2 and a second thickness D2, and the second carrier transport layer and the second light absorption layer satisfy Φ1+Φ2−2π(n1D1+n2D2)/λ=2mπ. Φ1 represents a reflective phase difference between the second electrode layer the second light absorption layer, Φ2 represents a reflective phase difference between the second carrier transport layer and second light absorption layer, λ represents an absorption wavelength of the first light absorption layer, and m represents 0 or an integer.
US08809672B2 Nanoneedle plasmonic photodetectors and solar cells
The present disclosure provides a catalyst-free growth mode of defect-free Gallium Arsenide (GaAs)-based nanoneedles on silicon (Si) substrates with a complementary metal-oxide-semiconductor (CMOS)-compatible growth temperature of around 400° C. Each nanoneedle has a sharp 2 to 5 nanometer (nm) tip, a 600 nm wide base and a 4 micrometer (μm) length. Thus, the disclosed nanoneedles are substantially hexagonal needle-like crystal structures that assume a 6° to 9° tapered shape. The 600 nm wide base allows the typical micro-fabrication processes, such as optical lithography, to be applied. Therefore, nanoneedles are an ideal platform for the integration of optoelectronic devices on Si substrates. A nanoneedle avalanche photodiode (APD) grown on silicon is presented in this disclosure as a device application example. The APD attains a high current gain of 265 with only 8V bias.
US08809667B2 Thermoelectric semiconductor component
A thermoelectric semiconductor component, comprising an electrically insulating substrate surface and a plurality of spaced-apart, alternating p-type (4) and n-type semiconductor structural elements (5) which are disposed on said surface and which are connected to each other in series in an electrically conductive manner alternatingly at two opposite ends of the respective semiconductor structural elements by conductive structures, in such a way that a temperature difference (2ΔT) between the opposite ends produces an electrical voltage between the conductive structures or that a voltage difference between the conductive structures (7, 9; 13, 15) produces a temperature difference (2ΔT) between the opposite ends, characterized in that the semiconductor structural elements have a first boundary surface between a first and a second silicon layer, the lattice structures of which are considered ideal and are rotated by an angle of rotation relative to each other about a first axis perpendicular to the substrate surface and tilted by a tilt angle about a second axis lying parallel to the substrate surface, in such a way that a dislocation network is present in the region of the boundary surface.
US08809666B1 Electronic drum induction structure
The present invention relates to an electronic drum induction structure, and more particularly to a structure eliminating noise generated from a drumhead of an electronic drum so as to transmit electronic induction sound only. The electronic drum induction structure of the present invention is mainly formed by combining an induction ring with a woven net, where the induction ring is an annular foam, inside which an induction sheet is sandwiched, and an induction signal line is connected; the woven net is formed by weaving resin fibers, and an induction ring is attached on the rear face of the woven net at the inner diameter of the circumference thereof.
US08809665B2 Electronic percussion gestures for touchscreens
Methods, computer program products, and systems for receiving gestures and producing percussion instrument signals are disclosed. An exemplary method includes receiving a gesture on an area of a touchscreen representing a percussion instrument and generating a signal based on the gesture and area. The gesture can be a single point initiation touch on an area, and a drag into another area. The gesture can be a two-touch point initiation touch on a first area, and a change in distance between the points to change a first parameter such as repeat rate. Such gestures can further include translation of the touch points as a group along an axis to change a second parameter such as volume, pitch, or reverb.
US08809659B2 Keyboard device for electronic musical instrument
A keyboard device includes plural white and black keys 11w, 11b that rock according to a key depression/release operation. Positions of key support portions 13w, 13b supporting the plural white and black keys 11w, 11b in the longitudinal direction are set to be different from one another. The keyboard device also includes hammers 16w, 16b that rock with the rocking movement of the plural white and black keys 11w, 11b. The plural white and black keys 11w, 11b include drive units 11w1, 11b1 that drive the hammers 16w, 16b. The pivot centers of the hammers are located on the same straight line extending in the lateral direction. The drive unit 11b1 is located anterior to the drive unit 11w1. An upper-limit stopper 21 and a lower-limit stopper 20, which restrict the rocking movement of the hammers 16w, 16b, are provided to extend in the lateral direction.
US08809658B2 Keyboard device for electronic musical instrument
A keyboard device includes plural white and black keys 11w, 11b that rock according to a key depression/release operation. Positions of key support portions 13w, 13b supporting the plural white and black keys 11b, 11w in the longitudinal direction are set to be different from one another. The keyboard device also includes hammers 16w, 16b that rock with the rocking movement of the plural white and black keys 11w, 11b. The plural white and black keys 11w, 11b include drive units 11w1, 11b1 that drive the hammers 16w, 16b. The drive units 11w1, 11b1 and the pivot centers of the hammers are located on the same straight line extending in the lateral direction. An upper-limit stopper 21 and a lower-limit stopper 20, which restrict the rocking movement of the hammers 16w, 16b, are provided to extend in the lateral direction.
US08809653B2 Inbred corn line BC110
An inbred corn line, designated BC110, is disclosed. The invention relates to the seeds of inbred corn line BC110, to the plants and plant parts of inbred corn line BC110 and to methods for producing a corn plant, either inbred or hybrid, by crossing inbred corn line BC110 with itself or another corn line. The invention also relates to products produced from the seeds, plants, or parts thereof, of inbred corn line BC110 and/or of the hybrids produced using the inbred as a parent. The invention further relates to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other inbred corn lines derived from inbred corn line BC110.
US08809652B2 Inbred corn line LM3
An inbred corn line, designated LM3, is disclosed. The invention relates to the seeds of inbred corn line LM3, to the plants and plant parts of inbred corn line LM3 and to methods for producing a corn plant, either inbred or hybrid, by crossing inbred corn line LM3 with itself or another corn line. The invention also relates to products produced from the seeds, plants, or parts thereof, of inbred corn line LM3 and/or of the hybrids produced using the inbred as a parent. The invention further relates to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other inbred corn lines derived from inbred corn line LM3.
US08809650B1 Maize variety inbred PH1MHD
A novel maize variety designated PH1MHD and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1MHD with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1MHD through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1MHD or a locus conversion of PH1MHD with another maize variety.
US08809649B1 Maize variety hybrid X13B607
A novel maize variety designated X13B607 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X13B607 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X13B607 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X13B607, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X13B607. This invention further relates to methods for producing maize varieties derived from maize variety X13B607.
US08809646B1 Maize hybrid X13C726
A novel maize variety designated X13C726 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X13C726 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X13C726 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X13C726, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X13C726. This invention further relates to methods for producing maize varieties derived from maize variety X13C726.
US08809644B1 Maize hybrid X03C201
A novel maize variety designated X03C201 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X03C201 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X03C201 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X03C201, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X03C201. This invention further relates to methods for producing maize varieties derived from maize variety X03C201.
US08809643B1 Maize hybrid X00C222
A novel maize variety designated X00C222 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X00C222 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X00C222 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X00C222, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X00C222. This invention further relates to methods for producing maize varieties derived from maize variety X00C222.
US08809642B1 Maize hybrid X13C788
A novel maize variety designated X13C788 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X13C788 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X13C788 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X13C788, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X13C788. This invention further relates to methods for producing maize varieties derived from maize variety X13C788.
US08809641B1 Maize inbred PH1MB5
A novel maize variety designated PH1MB5 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1MB5 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1MB5 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1MB5 or a locus conversion of PH1MB5 with another maize variety.
US08809639B2 Soybean variety D2011909
The invention relates to the soybean variety designated D2011909. Provided by the invention are the seeds, plants and derivatives of the soybean variety D2011909. Also provided by the invention are tissue cultures of the soybean variety D2011909 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety D2011909 with itself or another soybean variety and plants produced by such methods.
US08809634B1 Lettuce variety crispita
The present invention provides novel lettuce cultivar Crispita and plant parts, seed, and tissue culture therefrom. The invention also provides methods for producing a lettuce plant by crossing the lettuce plants of the invention with themselves or another lettuce plant. The invention also provides lettuce plants produced from such a crossing as well as plant parts, seed, and tissue culture therefrom.
US08809632B2 Lettuce cultivar Carlsbad
A lettuce cultivar, designated Carlsbad, is disclosed. The invention relates to the seeds of lettuce cultivar Carlsbad, to the plants of lettuce cultivar Carlsbad and to methods for producing a lettuce plant by crossing the cultivar Carlsbad with itself or another lettuce cultivar. The invention further relates to methods for producing a lettuce plant containing in its genetic material one or more transgenes and to the transgenic lettuce plants and plant parts produced by those methods. This invention also relates to lettuce cultivars or breeding cultivars and plant parts derived from lettuce cultivar Carlsbad, to methods for producing other lettuce cultivars, lines or plant parts derived from lettuce cultivar Carlsbad and to the lettuce plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid lettuce seeds, plants, and plant parts produced by crossing cultivar Carlsbad with another lettuce cultivar.
US08809625B2 Compositions and methods for the suppression of target polynucleotides from Lygus
Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a pest from the Lygus genus, is capable of decreasing the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides various target polynucleotides from specific polypeptide families as disclosed herein, or active variants thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest. Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
US08809621B2 Yield traits for maize
Methods for introgressing an allele of interest of a locus associated with a yield trait into Zea mays germplasm are provided. In some embodiments, the methods include providing a Zea mays plant that contains an allele of interest of a locus associated with a yield trait, wherein the locus associated with the yield trait is identifiable by PCR amplification of a Zea mays nucleic acid with a pair of oligonucleotides primers as disclosed herein, and introgressing the allele of interest into Zea mays germplasm that lacks the allele. Also provided are methods for identifying Zea mays plants that contain at least one allele associated with improved yield, improved maize plants, elite Zea mays plants, biomass produced from improved Zea mays plants, isolated and purified genetic markers, and compositions that include an amplification primer pair capable of amplifying a Zea mays nucleic acid to generate a Zea mays marker amplicon.
US08809619B2 Knockout mice for a P450 gene cluster
The invention relates to the generation of mouse models of drug metabolism in which clusters of genes that are involved in drug metabolism have been knocked out. The development of new drugs and chemicals for therapeutic use or for other purposes is extremely complex. Of particular importance is the understanding of how these chemical agents are handled in the body, whether they have appropriate pharmacokinetics and whether, as a consequence of metabolism, any safety issues arise. Many of the proteins that are involved in the metabolism, disposition and elimination of drugs are members of multigene families that exhibit very marked species differences in gene number, function and regulation. For these reasons, experiments carried out in laboratory animals to establish routes of metabolism or toxicity can be severely compromised and, as a consequence, do not faithfully represent the human situation. One example of this complexity is reflected in the mammalian cytochrome P450 system, where the sizes of multigene families of proteins which carry out particular metabolic functions vary enormously between species.
US08809615B2 Adhesive preparation
An adhesive preparation comprising a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a interlock woven fabric subjected to crimping processing, the adhesive layer contains 10% by mass or more of methyl salicylate with respect to the total mass of the layer, the whole adhesive preparation has moisture permeability of 1 to 350 g/m2·24 hr measured at a temperature of 40° C. and a relative humidity of 90%, and the methyl salicylate has a plasma AUC0-24 ranging from 3.0 to 60.0 ng·hr/mL in terms of a mean±standard deviation, and salicylic acid as a metabolite of the methyl salicylate has a plasma AUC0-24 ranging from 5000 to 13000 ng·hr/mL in terms of a mean±standard deviation, when the adhesive preparation is applied to a human skin for 8 hours such that an application amount of the adhesive layer applied is 50 to 300 g/m2 and a contact area is 280 cm2.
US08809613B2 Method for preparing linear alpha-olefins
The present invention relates to a method for preparing linear alpha-olefins (LAO) by oligomerization of ethylene in the presence of a solvent and homogeneous catalyst, comprising the steps of: (i) feeding ethylene, solvent and catalyst into an oligomerization reactor, (ii) oligomerizing the ethylene in the reactor, (iii) removing a reactor outlet stream comprising solvent, linear alpha-olefins, optionally unreacted ethylene and catalyst from the reactor via a reactor outlet piping system, (iv) dosing at least one additive selected from the group consisting of alcohols, poly-ethylene glycols, polyethylene glycol monoethers, polyethylene glycol diethers, polyamines, amines, amino alcohols and surfactants, (v) transferring the reactor outlet stream containing the additive to a catalyst deactivation and removal section, and (vi) deactivating the catalyst with caustic and removing the deactivated catalyst from the reactor outlet stream, wherein the residence time of the additive in the reactor outlet stream prior to mixing with caustic is at least 1 second preferably at least 5 seconds, more preferably at least 10 seconds.
US08809612B2 Purification of an olefinic fraction by adsorption on alumina-faujasite co-granules
Method for preparation of an adsorbent that comprises successive shaping stages by co-granulation of a faujasite-type zeolite powder A, with a powder B that consists of alumina, whereby the ratio per unit of mass of the powder A in the mixture of powders A and B is between 10 and 70%, for treatment under water vapor and drying.The invention also relates to a process for adsorption of organic contaminants that contain at least one heteroatom and that are present in an olefinic feedstock that comprises at least 50% by volume of hydrocarbons, whereby this process comprises the stage for bringing the olefinic feedstock into contact with the adsorbent that is obtained by the preparation method according to the invention.
US08809611B2 Method for removal and recovery of organic amines from a hydrocarbon stream
A method for removal and recovery of an organic amine from a hydrocarbon stream containing the amine, including: i) mixing the hydrocarbon stream containing the amine with an aqueous inorganic acid in a volumetric ratio of hydrocarbon stream:aqueous inorganic acid of greater than 1:1-5:1, preferably 1.5:1-4:1, more preferably 3:1, ii) phase separating of hydrocarbon and aqueous phase; iii) removing the hydrocarbon phase and optionally further purifying thereof, iv) optionally recycling at least a part of the hydrocarbon phase obtained in step (iii) into mixing step (i), v) mixing the aqueous phase obtained in step (iii) with an aqueous alkaline solution, vi) phase separating of an aqueous phase and an organic phase formed, vii) removing the organic phase obtained in step (vi) and optionally further purifying thereof.
US08809610B2 Process for producing paraffinic hydrocarbons
A process for producing paraffinic hydrocarbons from a feedstock comprising triglycerides, diglycerides, monoglycerides and/or fatty acids, the process comprising the following steps: (a) hydrode oxygenating the triglycerides, diglycerides, monoglycerides and/or fatty acids in the feedstock by contacting hydrogen and the feedstock with a hydrogenation catalyst at a temperature in the range of from 250 to 380° C. and a total pressure in the range of from 20 to 160 bar (absolute), to obtain an effluent comprising paraffinic hydrocarbons and water; (b) separating a liquid stream rich in paraffinic hydrocarbons from the effluent obtained in step (a); and (c) hydroisomerising the paraffinic hydrocarbons in the liquid stream rich in paraffinic hydrocarbons by contacting hydrogen and the liquid stream with a hydroprocessing catalyst comprising sulphided Ni and sulphided W or Mo as hydrogenation components on a carrier comprising amorphous silica-alumina and/or a zeolitic compound at a temperature in the range of from 280 to 450° C. and a total pressure in the range of from 20 to 160 bar (absolute).
US08809604B2 Sugar alcohol split injection conversion
A method of hydrotreating liquefied biomass feedstock with diesel feedstock to produce alkanes is demonstrated that prevents damage to the reactor catalyst, reduces coke production, and converts nearly all of the polyols to alkanes. In order to mitigate the potential coking issue and to moderate the temperature of the catalyst bed while maintaining high conversion for sugar alcohol to hydrocarbon via a hydrotreating process, a diesel feedstock is fed over the reactor catalyst with multiple injections of polyol feedstock along the reactor.
US08809594B2 Dual catalyst system for the self-condensation of alcohols
Disclosed is a process for the production of higher aldehydes from lower alcohols using a two-stage vapor phase heterogeneous catalyst system. Ethanol feeds afford aldehydes such as butyraldehyde and crotonaldehyde while butanol feeds yield 2-ethylhexanal and 2-ethylhexenal. Higher product selectivities are obtained when the alcohol is first dehydrogenated in the upper catalyst stage followed by aldol condensation of the resulting lower aldehyde to a higher aldehyde.
US08809591B2 Process for the manufacture of TMHQ
The present invention is directed to a process for the manufacture of 2,3,5-trimethyl-hydro-p-benzoquinone comprising the following steps: a) hydrogenating 2,6-dimethyl-p-benzoquinone with hydrogen in the presence of a hydrogenation catalyst in an organic solvent to obtain 2,6-dimethyl-hydro-p-benzoquinone; b) reacting 2,6-dimethyl-hydro-p-benzoquinone with a secondary amine and formal-dehyde in an organic solvent to obtain 2,6-dimethyl-3-(N,N-disubstituted aminomethyl)-hydro-p-benzoquinone; c) reacting 2,6-dimethyl-3-(N,N-disubstituted aminomethyl)-hydro-p-benzoquinone with hydrogen in the presence of a hydrogenolysis catalyst in an organic solvent to obtain 2,3,5-trimethylhydro-p-benzoquinone; wherein the organic solvent in all steps a), b) and c) is independently selected from the group consisting of methyl tert.-butyl ether, ethyl tert.-butyl ether, methyl tert.-amyl ether, methoxycyclopentane and any mixtures thereof. Preferably the organic solvent used in all steps a), b) and c) is the same.
US08809588B2 Method for producing aromatic amines
The invention relates to a process for preparing aromatic amines by catalytically hydrogenating the corresponding aromatic nitro compound, which comprises using a copper catalyst with a support comprising SiO2, the SiO2 having been prepared by wet grinding and subsequent spray drying.
US08809585B2 Synthesis scheme for lacosamide
The present invention is concerned with an improved method of producing (R)-2-acetamido-N-benzyl-3-methoxypropionamide (lacosamide) comprising the 0-methylation of a compound of formula (I) to produce a compound of formula (II) in a single step reaction.
US08809584B2 N-substituted-N-phenylethylsulfonamides for the identification of biological and pharmacological activity
Novel compounds are continually sought after to treat and prevent diseases and disorders. The invention relates to N-substituted-N-phenylethylsulfonamides useful for being biologically and pharmacologically screened, and to contribute to the exploration and identification of new lead molecules that are capable of modulating the functional activity of a biological target.
US08809581B2 Method of making 6-aminocaproic acid as active pharmaceutical ingredient
The present invention provides a method for making 6-aminocaproic acid as an active pharmaceutical ingredient. The method comprises: performing a hydrolysis procedure to have ε-caprolactam react with acid or base to generate a first reaction mixture, performing a modification procedure to have a solubility regulating agent reacts with 6-aminocaproic acid in the first reaction mixture to form a second reaction mixture including an aminocaproic acid intermediate, performing a separation procedure to have the intermediate separated from the second reaction mixture and performing a hydrogenation procedure to have the aminocaproic acid intermediate hydrogenated to form a 6-aminocaproic acid product.
US08809580B2 Methods of preparing fluorinated carboxylic acids and their salts
A method for preparing fluorinated carboxylic acids and theirs salts is described comprising subjecting a fluorinated to at least one first and at least one second oxidizing agent to produce a highly fluorinated carboxylic acid or their salts. The first oxidizing agent is a compound that can be converted, by action of the second oxidizing agent, into a reactive species capable of oxidizing the fluorinated alcohol.
US08809578B2 Compound ramalin and use thereof
The present invention relates to a novel compound having excellent antioxidant activity, isolated from Ramalina terebrata, and more particularly to a novel compound, RAMALIN™, having excellent antioxidant activity, isolated from the Antarctic lichen Ramalina terebrata, a method for preparing the RAMALIN™, and a pharmaceutical composition, a functional food and a functional cosmetic composition, which contain the RAMALIN™ as an active ingredient. The RAMALIN™ according to the invention has significantly excellent antioxidant effects compared to commercially available antioxidants, and thus can be widely used in agents for treating oxidation-related diseases, anti-aging functional foods, functional cosmetic products for skin whitening and wrinkle reduction, etc.
US08809573B2 Carbonylation process
A process for the production of acetic acid and/or methyl acetate by the carbonylation of methanol, methyl acetate and/or dimethyl ether with carbon monoxide in the presence of a desilicated mordenite catalyst.
US08809571B2 Process for the production of 2-amino-2-[2-(4-C2-20-alkyl-phenyl)ethyl]propane-1,3-diols, and to compounds for use therein
The present invention relates to improved processes for the production of 2-amino-2-[2-(4-C2-20-alkyl-phenyl)ethyl]propane-1,3-diols, and to compounds for use therein.
US08809562B2 Use of metallocene compounds for cancer treatment
Metallocene compounds and pharmaceutical compositions containing these metallocene compounds are disclosed and described. Methods of treating cancer employing such metallocene compounds and pharmaceutical compositions also are provided.
US08809561B2 Hybrid, organic-inorganic, crystalline, porous silicates and metal-silicates
The present invention relates to new hybrid, organic-inorganic hybrid silicates and metal-silicates characterized by a crystalline structure containing structural units having formula (a), wherein R is an organic group possibly containing one or more element T selected from Group IIIB, IVB, VB and from transition metals. A process starting from cyclic trisilanes for the preparation of said materials, is also described. These materials can be used as molecular sieves, adsorbents, in the field of catalysis, in the field of electronics, in the field of sensors, in the area of nanotechnology.
US08809554B2 Process for the preparation of sulfamide derivatives
The present invention is directed to a process for the preparation of sulfamide derivatives.
US08809553B2 Process for the preparation of pteridine derivatives
The application discloses a process for the preparation of 5-deoxy-L-arabinose of formula (VI); comprising the conversion of a compound of formula (XII); wherein n is 0, 1 or 2; which can be used as intermediate for the synthesis of sapropterin.
US08809552B2 Azetidine compounds, compositions and methods of use
Provided are compounds of Formula I, R1-L1-A-L2-R2  (I), and stereoisomers, tautomers and pharmaceutically acceptable salts thereof, wherein A, L1, L2, R1 and R2 are defined herein. The present invention also provides a pharmaceutical composition and methods of using such compounds. The compounds are useful for therapy and/or prophylaxis in a patient, and in particular to inhibitors of Soluble Epoxide Hydrolase (sEH).
US08809551B1 Polymethine compounds and their use as fluorescent labels
The present disclosure relates to new polymethine compounds and their use as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
US08809548B2 Hepatitis C virus inhibitors
The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
US08809547B2 Heterocyclic compounds as pesticides
The present application relates to the use of heterocyclic compounds, some of which are known, for controlling animal pests, including arthropods and in particular insects, furthermore to novel heterocyclic compounds and to processes for their preparation.
US08809543B2 Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge for electrophotographic image forming apparatus
An N-phenyl-diphenylisoindole derivative having the following formula (1): wherein each of R1 and R2 represents a hydrogen atom, a substituted or an unsubstituted alkyl group, a substituted or an unsubstituted alkoxy group, a substituted or an unsubstituted phenyl group, or a substituted or an unsubstituted phenoxy group; R3 represents a hydrogen atom, a substituted or an unsubstituted alkyl group, a substituted or an unsubstituted alkoxy group, a substituted or an unsubstituted phenyl group, a substituted or an unsubstituted phenoxy group, or has the following formula (2): wherein each of R4 and R5 represents a substituted or an unsubstituted alkyl group, or a substituted or an unsubstituted phenyl group; 1 represents an integer of from 1 to 4; and each of m and n represents an integer of from 1 to 5.
US08809541B2 Heterocyclic compound, and composition for treating inflammatory diseases using same
Provided are heterocyclic compounds, having effects of treating and preventing inflammatory diseases and treating skin wounds, and particularly, exhibiting effects of recovering disrupted skin barriers, mitigating inflammation, and pruritus. Also, a composition containing the compound as an effective component can be used to mitigate various inflammatory diseases and protease activated receptor-2 (PAR-2)-overexpressed diseases, and can be particularly used as a composition having an anti-inflammatory function in inflammatory skin diseases including atopic dermatitis and the like, by inhibiting PAR-2 activity.
US08809536B2 2,3-dihydrobenzo[1,4] dioxin-2-ylmethyl derivatives as alpha2C antagonists for use in the treatment of peripheric and central nervous system diseases
Compounds of formula I wherein X, Z, R1-R4, and m are as defined in the claims, exhibit alpha2C antagonistic activity, and are thus useful as alpha2C antagonists. Methods for the treatment of diseases and conditions of the peripheric system and the central nervous system are also disclosed.
US08809533B2 Bi- or tricyclic sterically hindered alkoxyamines and process for their preparation
The instant invention pertains to novel bi- or tricyclic sterically hindered alkoxyamines, their precursors, a process for their preparation and their use as light stabilizers for polymers or coatings, as flame retardants, as peroxide substitutes (rheology modifiers) or carbon radical scavengers.
US08809529B2 Imidazo[1,2-α]pyrazine derivatives
The present invention provides, among other things, imidazo[1,2-α]pyrazine derivatives according for Formula (Ia) or Formula (Ib). The derivatives are useful in any method which other coelenterazines have been used. For example, the derivatives may be used in a bioluminogenic method to detect the presence of certain compounds or molecules.
US08809527B2 Modulators of toll-like receptors
Provided are modulators of TLRs of Formula II: pharmaceutically acceptable salts thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.
US08809526B2 Synthesis of cyclopentaquinazolines
A method of producing 6-amino-cyclopenta[g]quinazolines, in enantiomerically enriched form, is provided. In particular, the method may be applicable to the synthesis of N—{N-{4-[N-((6S)-2 -hydroxymethyl-4-oxo-3,4,7,8-tetrahydro-6H-cyclo-penta[g]quinazolin-6-yl)-N-(prop-2 -ynyl)amino]benzoyl}-L-γ-glutamyl}-D-glutamic acid (ONX-0801).
US08809523B2 Method of making nanosized particles of phthalocyanine pigments
Nanoscale pigment particles of phthalocyanine pigments are prepared by providing a unsubstituted phthalocyanine chromogen material and a substituted phthalocyanine chromogen material, reacting the unsubstituted phthalocyanine chromogen material and the substituted phthalocyanine chromogen material to form a mixture of unsubstituted phthalocyanine dye molecules and substituted phthalocyanine dye molecules, and causing the substituted phthalocyanine dye molecules to non-covalently associate with the unsubstituted phthalocyanine dye molecules, so as to limit an extent of particle growth and aggregation and result in nanoscale pigment particles.
US08809522B2 Method of preparing a glycoside of a mono- or diacylglycerol product from a plant material
The present invention provides a method of preparing a glycoside of a mono- or diacylglycerol product from a plant material. The method comprises the steps of: (i) optionally milling the plant material, (ii) extracting the optionally milled plant material with a first aqueous extraction solution obtaining a first liquid phase and a first solid phase, (iii) separating the liquid phase from the solid phase to obtain a glycoside of mono- or diacylglycerol product, (iv) extracting the solid phase from step (iii) with a second extraction solution obtaining a second liquid phase and a second phase, and (v) separating the second liquid phase from the second solid phase to obtain a second and a third glycoside of mono- or diacylglycerol product, wherein the second extraction solution further comprises a cell wall degrading enzyme or a mixture of cell wall degrading enzymes.
US08809517B2 Method of inhibiting Alu RNA and therapeutic uses thereof
The presently-disclosed subject matter includes methods of identifying an Alu RNA inhibitor, and methods and compositions for inhibiting Alu RNA. Methods and compositions can be used for the treatment of geographic atrophy and other conditions of interest.
US08809514B2 Tripartite oligonucleotide complexes and methods for gene silencing by RNA interference
Provided herein are tripartite oligonucleotide complexes which can be administered to a cell, tissue or organism to silence a target gene. The tripartite oligonucleotide complexes of the disclosure may include a conjugate moiety that facilitates delivery to a cell, tissue or organism without the aid of a transfection reagent.
US08809512B2 RNA complexes, methods of their production and sensors and analytical methods involving same
The invention includes RNA complexes comprising at least three monomeric units of an RNA molecule, each monomeric unit comprising an RNA polymer having first and second helical domains that have respective first and second binding sites, wherein the first binding sites are adapted to binding to one another and are not adapted to bind to the second binding sites, and the second binding sites are adapted to binding to one another and are not adapted to bind to the first binding sites; such that the at least three monomeric units are adapted to self-assemble by forming pairs of cognate interactions and so as to form the RNA complex in a circular closed complex. The invention also includes derivatives of these complexes including aptamers, and analytical methods and devices using same.
US08809506B2 Antibodies and vaccines for use in therapeutic and diagnostic methods for α-synuclein-related disorders
A vaccine for delaying an onset of or for treatment of an α-synuclein-related disorder in an individual comprises a therapeutically effective amount of isolated stabilized soluble α-synuclein oligomer having a lower formation rate to a non-soluble aggregated form than a non-stabilized oligomer of the α-synuclein. An antibody for delaying an onset of or for treatment of an α-synuclein-related disorder in an individual binds soluble α-synuclein. Methods for delaying an onset of for treatment or for prevention of an α-synuclein-related disorder employ the vaccine or antibody. Methods of detecting α-synuclein oligomers employ the antibody.
US08809505B2 Mutant alpha-synuclein, and methods using same
The present invention relates to a mutant human alpha-synuclein with increased toxicity compared to wild-type alpha-synuclein, or a homologue thereof, wherein the mutant alpha-synuclein or homologue thereof comprises at least one amino acid substitution selected from the group consisting of a substitution at the alanine at position 56 (A56), at the alanine at position 76 (A76), at the methionine at position 127 (M127) and/or at the valine at position 118 (V118), as defined in the claims. Further, the invention relates to a polynucleotide encoding the mutant alpha-synuclein or homologue thereof, or an expression vector comprising said polynucleotide, a cell comprising the polynucleotide or expression vector, as defined in the claims. Also, a non-human animal comprising the cell of the invention is provided, as defined in the claims. Finally, the invention provides methods for identifying a substance that prevents or reduces toxicity of alpha-synuclein, as defined in the claims.
US08809504B2 Inhibitor which is deactivatable by a reagent produced by a target cell
The invention relates to molecules inhibiting biologically active compounds and further comprising moieties specifically cleavable by a reagent produced by a target cell. The invention relates to inhibitors that bind, inhibit, suppress, neutralize, or decrease activity of a biologically active agent. Inhibitors comprise at least one moiety that bind, inhibit, suppress, neutralize, or decrease activity of a biologically active agent and at least one moiety that can be cleaved specifically by a reagent produced by target cells. The cleavage deactivates the inhibitor. Following cleavage, the active agent is liberated into the local environment. Administration of the inhibitor alone or together with the active agent suppress the compound's activity until it reaches the proximity of a target cell. Targeted specific release enables the agent concentration in specific site to reach levels that have desired therapeutic effects without systemic toxicity.
US08809503B2 Optimized Fc variants and methods for their generation
The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
US08809499B2 Fusion protein of human fibroblast growth factor-21 and exendin-4
Provided is a fusion protein, which comprises human fibroblast growth factor 21 and glucagon-like-peptide-1 or its analogs. Also provided is the medicament composition comprising the fusion protein, which can be used for treating or preventing obesity, diabetes, hyperglycemia and hyperlipidemia etc.
US08809495B2 Peptides imparting cell permeability to lipid membrane structure and/or enhancing cell permeability of lipid membrane structure, and lipid membrane structure comprising lipid bound to such peptide as constituent lipid and having cell permeability or showing enhanced cell permeability
Provided are peptides imparting cell permeability to a lipid membrane structure and/or enhancing the cell permeability of a lipid membrane structure, and a lipid membrane structure which comprises, as a constituent lipid, a lipid bound to such a peptide and has cell permeability or shows enhanced cell permeability. The amino acid sequences of the peptides imparting cell permeability to a lipid membrane structure and/or enhancing the cell permeability of a lipid membrane structure are represented by: LX1X2X1X1X1L, LLX2X1X1X1L and LX1X2X1X1L (wherein L represents a leucine residue; X1 represents a polar amino acid residue; and X2 represents a polar, non-charged and branched chain amino acid residue).
US08809493B2 Resin extract, extraction process and uses thereof
The present invention generally relates to resins and uses thereof in composite materials and products. The present invention also relates to extraction processes for obtaining resins from plants and plant materials. The invention also relates to resin extracts obtained from a plant of the genus Triodia, commonly known as Spinifex, processes for obtaining resins, modified resins and composite products incorporating resins.
US08809488B2 Carboxylated polymers of intrinsic microporosity (PIMs) with tunable gas transport properties
A film of a carboxylated polymer of formula (I): wherein the sum of x, y and z is an integer from 10 to 10,000 and degree of hydrolysis is 0.05 or greater provides gas separation materials in which the degree of hydrolysis may be used to tune the selectivity of the gases to an optimal required range. Such films may be prepared by casting a film of a polymer of formula (II): wherein n is an integer from 10 to 10,000, and hydrolyzing all or a portion of the —CN groups to form —COOH groups.
US08809487B2 Process for manufacture of conjugated polymer compositions for solar cell applications
The present disclosure relates to a process for the synthesis of a conducting polymer comprising a benzothiadiazole acceptor and indeno-fluorene donor of formula [IV].
US08809483B1 Functionalization of poly(phenylene) by the attachment of sidechains
A composition and an anion exchange membranes including a composition and a method of forming a composition including a compound including a poly(phenylene) backbone represented by the following formula: wherein each of R1, R2 and R3 may be the same or different and is H or an unsubstituted or inertly-substituted aromatic moiety; wherein each of Ar1 and Ar2 may be the same or different and is an unsubstituted or inertly-substituted aromatic moiety; wherein each of R6, R7, R8, R9, R10 and R11 is H or a monovalent hydrocarbon group including two to 18 carbon atoms, with the proviso that each R6, R7, R8, R9, R10 and R11 cannot be H; and wherein each of Y6, Y7, Y8, Y9, Y10 and Y11 may be the same or different and is H or a functional group.
US08809479B2 Moisture curable silylated polymer compositions containing reactive modifiers
A moisture-curable resin composition comprising (a) a moisture-curable polymer having at least one hydrolysable silyl group; (b) a reactive modifier; (c) a catalyst for catalyzing the reaction between the moisture-curable polymer (a) and reactive modifier (b) under curing conditions; and optionally, the composition can contain one or more conventional components, including pigments, fillers, curing catalysts, dyes, plasticizers, thickeners, coupling agents, extenders, volatile organic solvents, wetting a agents, tackifiers, crosslinking agents, thermoplastic polymers, ultraviolet stabilizers, and combination thereof. The moisture-curable resin composition is useful in the production of adhesives including hot melt adhesives, primers, sealants and coatings.
US08809477B2 Formaldehyde-free protein-containing binder compositions
A wood-containing composite are described that may include a lignocellulosic material, and a formaldehyde-free binder in contact with at least a portion of the lignocellulose material. The binder is formed from a binder composition that includes a soy flour, a polymer, and a crosslinking agent, at least a portion of each of which are covalently crosslinked to each other in the binder. Also described are methods of making wood-containing composites by providing a pre-mixed, one-part binder composition of at least 60 wt. % soy flour, a polymer, and a crosslinking agent. The binder composition is applied to lignocellulosic material, and the combination may be heated at a temperature of about 100° C. or more to cure the binder composition into a binder. The cured binder has the soy protein, polymer, and crosslinking agent covalently bonded to each other.
US08809474B2 Carboxyl group-containing polymer composition
The present invention provides a carboxyl group-containing polymer composition that exhibits excellent anti-soil redeposition ability in fabric washing. The carboxyl group-containing polymer composition contains a carboxyl group-containing polymer, which includes specific ratios of a structure unit (a) derived from an acrylic acid-based monomer (A) and a structure unit (b) derived from a sulfonic acid group-containing monomer (B) and has a specific weight average molecular weight, and a specific amount of an adduct of a hydrogen sulfite to the acrylic acid-based monomer (A).
US08809472B2 Process of melt index control
A method comprising contacting an olefin in the presence of a catalyst and a melt index modifier (MIM) under conditions suitable to form a polyolefin and recovering the polyolefin, wherein the polyolefin melt index is increased by at least about 25%, wherein the normalized catalyst activity is decreased by less than about 10%, and wherein the MIM is characterized by the general formula R1—HC═CH—R2 or R3R4C═CH2 where R1, R2, R3, R4 are each selected from the group consisting of a non-aromatic organyl group.
US08809471B2 Synthesis of making 2,3,3,3-tetrafluoropropene containing fluoropolymers
The invention relates to a method for synthesizing 2,3,3,3-tetrafluoropropene containing fluoropolymers using non-fluorinated surfactants in an emulsion process. No fluorinated surfactants are used in the process, and a persulfate initiator is used as the primary initiator. The process produces high molecular weight copolymers.
US08809465B2 Thermoplastic resin pellets and method for preparing same
The present invention relates to resin pellets which comprises a thermoplastic resin (A) and an oxidation catalyst (B) which is not supported by any carrier, wherein if the peak area in the vicinity of 1715 cm−1 is defined to be Ic and the peak area observed in the vicinity of 1470 cm−1 is defined to be Im in the IR spectroscopic measurement of the pellets, the ratio: Ic/Im observed for the surface of the pellet is greater than that observed for the interior thereof. The pellets are thermoplastic resin pellets excellent in the oxygen-absorbing capacity and accordingly, they can suitably used as pellets for molding an oxygen absorptive resin article.
US08809464B2 Polymers functionalized with halosilanes containing an amino group
A method for preparing a functionalized polymer, the method comprising the steps of preparing a reactive polymer, and reacting the reactive polymer with a halosilane compound containing an amino group.
US08809463B2 Method of preparing rubber latex having high polymerization stability
Disclosed is a method for preparing a rubber latex which includes adding a basic solution to an initial reaction hydrophilic monomer and a small amount of fat-soluble monomer when a polymerization conversion ratio is 90% or more to form particles having a small diameter and superior stability, ionizing an end of the particles to secure stability of the particles and growing the formed particles, and thereby obtains a stable latex with a large particle diameter using a minimal amount of emulsifying agent and minimizes gas generation and heat discoloration derived from the emulsifying agent.
US08809462B2 Ethylene-α-olefin copolymer, molded article, catalyst for copolymerization, and method for producing an ethylene-α-olefin copolymer
An ethylene-α-olefin copolymer comprising monomer units derived from ethylene and monomer units derived from an α-olefin having 3 to 20 carbon atoms, having a density (d) of 860 to 950 kg/m3, having a melt flow rate (MFR) of 0.01 to 100 g/10 min, having a bimodal molecular weight distribution, and having a single melting peak measured by a differential scanning calorimeter (DSC).
US08809456B2 Polyolefin compositions and methods of production thereof
This invention relates to methods for producing an alkene terminated polystyrene, including: contacting a styrenic block copolymer and an alkene in the presence of a metathesis catalyst under conditions sufficient to produce an alkene terminated polystyrene having an unsaturation functionality of at least 0.7 and a MWD of about 1.5 or less. Methods for producing functionalized polymers and polyethylene blend composition comprising these functionalized polymers are also disclosed.
US08809452B2 Damage self-reporting polymer materials having at least two phases
A synthetic material (22), a sensor comprising the synthetic material (22) and a method for making the synthetic material (22) and the sensor, respectively, as well as the use of this synthetic material (22) as a construction material and/or a high performing material, especially in the areas of aeronautics, aerospace, automotive, wind turbines and sporting goods. The synthetic material (22) comprising at least two phases (2, 9) and an optical detectable component (26, 16), wherein at least one of said phases is a solid phase building a matrix (20) of the synthetic material (22), and wherein the optical detectable component (26, 16) changes its optical properties (symbol 5, 7) when its intact structure is perturbed (8/26′), said optical detectable component (26, 16) is bond to both phases (2, 9) of the synthetic material (22).
US08809451B2 Fluorinated dicarboxylic acid derivative and polymer obtained therefrom
According to the present invention, a polymer is obtained by polycondensation of a fluorinated dicarboxylic acid derivative of the general formula (M-1) or an acid anhydride of the fluorinated dicarboxylic acid with a polyfunctional compound having two to four reactive groups corresponding in reactivity to carbonyl moieties of the fluorinated dicarboxylic acid derivative or acid anhydride. [Chem. 134] AOCF2C-Q-CF2COA′  (M-1) In the above formula, Q represents a divalent organic group having a substituted or unsubstituted aromatic ring; and A and A′ each independently represent an organic group. This polymer exhibits a sufficiently low dielectric constant for use as a semiconductor protection film and has the capability of forming a film at a relatively low temperature of 250° C. or lower.
US08809448B2 Aqueous polymer dispersions and products from those dispersions
A method for forming a heat sealable coating on a substrate, wherein the substrate is formed from at least one oriented polymer is shown. The method includes depositing an aqueous polymer dispersion on the substrate, wherein the aqueous polymer dispersion includes (A) at least one thermoplastic resin; (B) at least one dispersing agent; and (C) water; wherein the dispersion has a pH of less than 12, and drying the dispersion to form a first layer.
US08809446B2 Substituted 3-oxopentanoates and their uses in coating compositions
Substituted 3-oxopentanoates are disclosed that correspond to the following formula 1: in which R is hydrogen, or a methyl group; X is a straight-chain, branched, or cyclic alkyl or alkyl ether group having from 1 to 15 carbon atoms or aromatic group having from 6 to 15 carbon atoms; and Y1 and Y2 are independently hydrogen or an alkyl having 1 to 2 carbon atoms. Also disclosed are emulsion polymers, suspension polymers, and solution polymers that comprise residues from the substituted 3-oxopentanoate monomers, and that may also include one or more additional ethylenically unsaturated monomers. Also disclosed are coating compositions that include a latex emulsion polymer and the substituted 3-oxopentanoate monomer of formula 1 provided as a coalescent.
US08809445B2 Room temperature cured vinyl silazane compositions
A polysilazane composition, formulated from a vinyl silazane and an organometallic accelerator, and associated methods thereof.
US08809443B2 Dispersant composition
The present invention relates to a composition containing a particulate solid, a non-polar organic medium, and a compound obtained/obtainable by reacting an aromatic amine with hydrocarbyl-substituted acylating agent, wherein the hydrocarbyl-substituted acylating agent is selected from the group consisting of an oligomer or polymer from condensation polymerization of a hydroxy-substituted C10-30 carboxylic acid into a polyester, an optionally hydroxy-substituted C10-30 carboxylic acid, a C10-30-hydrocarbyl substituted acylating agent, and a polyolefin-substituted maleic anhydride. The invention further provides compositions for inks, thermoplastics, plasticizers, plastisols, crude grinding and flush.
US08809437B2 Method of manufacturing nanoparticle dispersion liquid
The present invention provides a method of producing a nanoparticle dispersion liquid, including: altering a surface of a nanoparticle in the presence of an ion by contacting a complex that includes the nanoparticle and a solid material present around the nanoparticle with a surface altering agent-containing liquid, that includes a surface altering agent for altering the surface of the nanoparticle and a solvent for dissolving the solid material and that has a viscosity of 1.10 mPa·s or more at 25° C.; and a dispersing step of dispersing the surface-altered nanoparticle in the solvent.
US08809435B2 Process enhancement via stimuli responsive particle surfaces
Methods for enhancing the processing of a polymer composite are provided herein. in some embodiments, a method for enhancing the processing of a polymer composite may include masking a at least one functional group on a surface of a particle by using a at least one protective group; mixing the particles into a polymer to form a composite; processing the composite; and applying a at least one stimulus to the composite during the processing of the composite or after processing of the composite is complete in order to remove the at least one protective group from the functional group.
US08809433B2 Barrier properties of substantially linear HDPE film with nucleating agents
Disclosed is a method for improving the barrier properties of polyethylene films. The method comprises mixing a substantially linear, high density polyethylene with a nucleating agent and converting the mixture into a film. The film made by the method of the invention has at least a 15% improvement on the water vapor barrier property and/or in the oxygen barrier property compared with the control film made from the same substantially linear, high density polyethylene but does not contain the nucleating agent.
US08809424B2 Process for preparing compositions based on a starchy component and on a synthetic polymer
Process for preparing a composition based on a synthetic polymer includes: introducing, into a reactor containing a softened or molten synthetic polymer, a non-plasticized starchy component and a plasticizer of the latter; and kneading the mixture obtained under conditions sufficient to obtain the plasticization of the starchy component by the plasticizer, and a homogeneous mixture of the synthetic polymer and of the plasticized starchy component. The reactor may especially be a co-rotating or counter-rotating single-screw or twin-screw extruder, for example a co-rotating twin-screw extruder. The synthetic polymer may advantageously be chosen from the group including polyethylenes (PE) and polypropylenes (PP), which are functionalized or unfunctionalized, polyamides (PA), thermoplastic polyurethanes (TPU), styrene-ethylene-butylene-styrene (SEBS) copolymers, preferably that are functionalized, amorphous polyethylene terephthalates (PETG) and blends thereof. The resulting compositions have improved characteristics, especially in terms of coloration and of mechanical properties, for example in terms of elongation at break.
US08809422B2 Epoxy resin curing indicator composition
Compositions comprising at least one epoxy resin and/or reactive diluents, at least one hardener for the at least one epoxy resin, at least one curing indicator, wherein the color of the composition changes depending on the curing degree, a process for determining sufficient cure of a composition comprising providing a composition comprising at least one epoxy resin and a hardener for the epoxy resin, adding a curing indicator, applying curing conditions to the colored composition until the composition changes its color and use of polymeric colorants as curing degree indicator, wherein the curing indicator is a polymeric colorant consisting of chromophores which are chemically bound to polymers having reactive groups.
US08809420B2 Method for preparing organic-inorganic composite materials
A method for preparing organic-inorganic composite materials is provided. It is a dispersion method that the inorganic phase is introduced into the polymer matrix uniformly. The core-shell structure, in which the inorganic materials are core and the organic materials are shell, is formed by first wrapping the inorganic materials with the organic materials in the same reactor. Therefore, the match between the polarity of inorganic phase and the polarity of polymer phase is increased.
US08809418B2 Methods, materials and apparatus for treating bone and other tissue
A bone cement comprising a first component and a second component, wherein contacting the first component and the second component produces a mixture which attains a high viscosity an initial period and the viscosity of the mixture remains relatively stable for a working time of at least 5 minutes after the initial setting period, and the mixture is suitable for in-vivo use.
US08809417B2 Soft shapeable adhesive paste
The present invention relates to a pressure sensitive paste composition for skin application. The paste comprises 10-50% (w/w) based on the total paste formulation of a blend of polar polyethylene copolymer(s) and polar oil.
US08809416B2 Waterborne coating composition comprising a polyester and a metal salt of a fatty acid
The invention relates to a waterborne coating composition comprising between 10 and 50% by weight of a water-dispersible and hydrophobic polyester resin, between 50 and 90% by weight of a metal salt of a fatty acid (with the amounts being based on the total solids content in the waterborne coating composition), and a base in an amount of between 70% and 130% of the number of carboxylic acid groups in the resin. It furthermore relates to a process for the preparation of said waterborne coating composition, and to its use.
US08809415B2 Golf ball having a cover layer with a purposed hardness gradient
Compositions for golf balls that include polyurethane and/or polyurea linkages and that are crosslinked in the soft segments of the polymer backbone to improve the crosslink density and effect a hardness gradient throughout the molded article.
US08809414B2 Photocurable composition and cured product
It is an object of the present invention to provide: a curable composition that has photocurability and provides a cured product excellent in insulating properties; and the cured product. This can be achieved by a photocurable composition that contains, as essential components, (A) a modified polyorganosiloxane compound having a photopolymerizable functional group and an SiH group, (B) a compound having a carbon-carbon double bond, and (C) a photopolymerization initiator. A thin film produced from the curable composition of the present invention has excellent insulating properties. Since the curable composition of the present invention can form a film by solution coating, it is applicable to provide thin-film insulating materials that can be formed by solution coating.
US08809409B2 Microporous polymers, methods for the preparation thereof, and uses thereof
A method for preparing a conjugated microporous polymer comprises the coupling of an alkynyl aryl monomer having a plurality of terminal alkyne groups with an iodo-or bromo-aryl monomer having a plurality of halogen atoms in the presence of a palladium (0) catalyst. The conjugated microporous polymer comprises nodes comprising at least one aryl unit and struts comprising at least one alkyne unit and at least one aryl unit, wherein a node is bonded from its aryl unit or units to at least two struts via alkyne units. Such polymers are useful in numerous areas such as separations, controlled release, gas storage and supports for catalysts.
US08809404B2 Siloxane polyether copolymers
The present invention is related to the preparation and use of moderately cross-linked (chin-extended), reverse (or “inverted”) surfactants, wherein the reverse surfactants comprise a polyether backbone with oligomeric or polymeric silicon-containing substitutions along the backbone. The present invention further describes crosslinked versions of the inverted surfactants, reaction products of alkenyl (allyl, vinyl, methallyl) functional copolymers (polyethers), silicone hydrides and cross-linking agents, which may be optionally reacted with water to react the remaining alkoxy groups. The crosslinking agent contains either SiH or Si-alkoxy groups or both. The compounds of the present invention exhibit only moderate cross-linking in order to be soluble or dispersible in appropriate solvents.
US08809401B2 Composition with improved skin penetration for transdermal delivery of tolterodine
Disclosed is a composition for transdermal administration containing tolterodine. The composition comprises lidocaine or a pharmaceutically acceptable salt thereof to achieve enhanced skin penetration. The composition enhances the skin penetration of tolterodine. Therefore, a successful commercial application of a tolterodine-containing transdermal preparation based on the composition can be expected.
US08809395B2 Methods for making valerenic acid derivatives and their use
The present invention is directed to compounds, intermediates and methods for making valerenic acid and its derivatives as well as the use of such compounds as GABAA receptor ligands.
US08809389B2 Substituted alkynyl phenoxy compounds as new synergists in pesticidal compositions
A composition comprising an alkynyl phenoxy compound of Formula (I) as a synergist and a pesticidal active ingredient is described, wherein R1 and R2, similar or different, are (C1-C4)alkyl or R1O— and R2O— together represent a group —O—CH2—O—, —O—CH(CH3)—O, —O—CH2—CH2—O—, —O—CH2—CH2—, R3 is (C1-C6)alkyl, (C3-C6)alkenyl or —B—(CH2—CH2—O)z-R6 where B is —CH2—O— or —O—, z is 0, 1 or 2 and R6 is (C1-C4)alkyl; R4 is hydrogen or methyl; R5 is hydrogen or methyl; x is an integer from 1 to 2; y is 0, 1 or 2; with the proviso that when R3 is —B—(CH2CH2—O)z-R6, y is 1 and 5-(propargyloxy)-benzo[1,3]dioxole is excluded.
US08809388B2 Vegetable oil composition containing palm mid-fraction fat and method of reducing plasma cholesterol
A method and composition for reducing the cholesterolemic effect in mammals of ingesting a blended nutritional fat composition containing a palm mid-fraction (PMF) hardstock fat combined with an unsaturated vegetable oil. The composition is solid or semi-solid at 20° C. and fluid at 35° C., and includes between 15% and 45% by weight linoleic acid. The weight ratio of disaturated triglyceride (DST) molecules to trisaturated triglyceride (TST) molecules is greater than 10:1, and the PMF hardstock fat contains approximately 50% to 95% by weight DST molecules, the majority of which contain either palmitic acid or a combination of palmitic and stearic acids at the sn-1 and sn-3 triglyceride positions and either oleic acid or linoleic acid at the sn-2 molecular position.
US08809385B2 Crystalline form of (2S)-(-)-N-(6-chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-sulfamide
The present invention is directed to a novel crystalline form of (2S)-(−)-N-(6-chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-sulfamide, pharmaceutical compositions containing said crystalline form and the use of said crystalline form in the treatment of anxiety and related disorders; bipolar depression and mania; depression; epilepsy and related disorders; epileptogenesis; glucose related disorders; lipid related disorders; migraine; obesity; pain; substance abuse; or for neuroprotection. The present invention is further directed to a process for the preparation of the novel crystalline form.
US08809384B2 Azaspirodecanone compounds
The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5 and A are as described herein, compositions including the compounds and methods of using the compounds.
US08809383B2 Pyrazole compound
The present invention relates to a novel serotonin reuptake inhibitor which also exhibits 5-HT2C antagonistic action (antidepressive and anxiolytic effects), in particular, 5-HT2C inverse agonistic action comprising Compound (1): or a pharmaceutically acceptable salt thereof wherein R1, R2, R3 and R4 are independently hydrogen or C1-6 alkyl etc.; R5 is C4-7 alkyl or —(CR8R9)r-E; R6, R7, R8 and R9 are independently hydrogen, fluorine or C1-6 alkyl; A is C6-10 aryl or heteroaryl etc.; r is 1, 2, 3 or 4; E is C3-8 cycloalkyl or C6-10 aryl etc.; L is oxygen, sulfur or —NR10—; n is 1, 2 or 3; R10 is hydrogen or C1-6 alkyl etc.; and X is hydrogen or halogen etc.
US08809382B2 5-oxo-ETE receptor antagonist compounds
The present invention relates to novel pharmaceutically-useful compounds which are antagonists of the 5-oxo-ETE receptors, such as the OXE receptor. These compounds have use as therapeutic and/or prophylactic agents for diseases characterized by tissue eosinophilia, such as inflammatory conditions including respiratory diseases. The invention also relates to pharmaceutical compositions, to the use of such compounds and compositions as medicaments, and to therapeutic methods.
US08809375B2 Spot-on pesticide composition
A spot-on pesticide composition for animals, specifically mammals, including dogs and cats, which composition comprises a combination of active components, including fipronil and a pyrethroid, and optionally an insect growth regulator, in doses and proportions which are parasiticidally effective against a variety of insects and pests, and in a formulation which is convenient for local application to the animal's skin, preferably localized over a small surface area.
US08809370B2 AMPK-activating heterocyclic compounds and methods for using the same
Disclosed are substituted pyridine compounds as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure wherein E, J, T, the ring system denoted by “B”, T, R3, R4, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.
US08809369B2 Tetrahydroquinoline derivatives
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt or ester thereof, wherein R1 to R8, A1 to A3 have the are as described herein and compositions including the compounds.
US08809366B2 Thienopyridine ester derivative containing cyano group, preparation method, use and composition thereof
A compound with the structure of the formula (I) or a pharmaceutically acceptable salt, a preparation method and use thereof are disclosed in the present invention, wherein R is cyano group. The compound provided by the present invention has an antiplatelet aggregation activity and can be used in preparing a medicament for preventing or treating cardiac and cerebral vascular diseases such as coronary artery syndromes, myocardial infarction and myocardial ischemia which are caused by platelet aggregation.
US08809363B2 Inhibitors of HIV replication
The present invention relates to novel 2,3,4-substituted 5,6,7,8-tetrahydro[1]benzothieno[2,3-b]pyridine compounds and pharmaceutically acceptable salts thereof, to compositions containing such compounds and to the use of such compounds as inhibitors of HIV replication.
US08809359B2 Phenyl amino pyrimidine bicyclic compounds and uses thereof
The present invention relates to phenyl amino pyrimidine bicyclic compounds formula I which are inhibitors of protein kinases including JAK kinases. In particular the compounds are active against JAK1, JAK2, JAK3 and TYK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.
US08809355B2 GABAA receptor modulators
The present invention relates to novel compounds of the general formula (I) having anxiolytic, anticonvulsant, sedative-hypnotic and myorelaxant conditions as well as anxiogenic, somnolytic and convulsant conditions in mammals, including humans, as GABAA receptor modulator.
US08809353B2 Quinazolines useful as modulators of voltage gated ion channels
The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
US08809351B2 Antiviral compound and cox-2 inhibitor combination therapy for functional somatic syndromes, including combination of famciclovir and celecoxib
The present invention relates to methods of treating fibromyalgia, by administering a therapeutically-effective combination of an antiviral component and a COX-2 inhibitor component. The invention is further related to pharmaceutical compositions comprising a combination of a therapeutically-effective amount of the antiviral compound famciclovir and a therapeutically-effective amount of the COX-2 inhibitor celecoxib. The invention is also related to methods of treating functional somatic syndromes by administering a therapeutically-effective combination of famciclovir and celecoxib.
US08809350B2 Purine and pyrimidine CDK inhibitors and their use for the treatment of autoimmune diseases
The present invention relates to the use of an inhibitor of CDK2 and/or CDK7 and/or CDK9, or a pharmaceutically acceptable salt thereof, in the preparation of a medicament for treating a disease associated with antinuclear antibodies, wherein the inhibitor of CDK2 and/or CDK7 and/or CDK9 or pharmaceutically acceptable salt thereof is administered in an amount sufficient to down-regulate the levels of antinuclear antibodies. A further aspect of the invention relates to a combination comprising an inhibitor of CDK2 and/or CDK7 and/or CDK9, or a pharmaceutically acceptable salt thereof, and methylprednisolone, and its use in the treatment of diseases associated with antinuclear antibodies, such as SLE.
US08809349B2 Processes for preparing isoquinolinones and solid forms of isoquinolinones
Polymorphs of chemical compounds that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including P13 kinase activity, are described herein. Also provided herein are processes for preparing compounds, polymorphs thereof, and pharmaceutical compositions thereof.
US08809348B2 6-arylmethyl substituted pyrazolo[3,4-d]pyrimidines
The invention relates to novel 6-arylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.
US08809347B2 Bicyclic aryl and bicyclic heteroaryl substituted triazoles useful as AXL inhibitors
Bicyclic aryl substituted triazoles or heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl. Methods of using the compounds in treating diseases or conditions associated with Axl activity are also disclosed.
US08809346B2 ANT-ligands molecules and biological applications
The invention relates to molecules ANT-ligands having a substituted nitrogeneous heterocycle A wherein A is a substituted pyrazinone of formula I wherein R1 is —(CH2)n—CO—OH; —(CH2)n—CO—OR; —(CH2)n—CO—NHR; —(CH2)n—CO—N(R,R′); —(CH2)n—OH; —(CH2)n—OR; —(CH2)n—OAr; —(CH2)n—C(R,R′)—(CH2)n—OH, R and R′, in the above radicals, being identical or different and representing H or a C1-C12 alkyl or cycloalkyl radical; and Ar is a phenyl or Het., Het. representing an heterocyclic radical with one or several hetero atoms selected between N, S and O, said phenyl or heterocycle being optionally substituted by one or several atoms, groups or radicals selected from halogen atoms such as Cl, Br, I, or halogenated groups such as —CCl3 or —CF3; one or several —OH, —OR, —COOH or —COOR groups; a phenyl; a linear or branched C1-C12 alkyl radical; —NH—COR; or —CN; said groups occupying the same or different positions on the phenyl or heterocyclic radical; a linear or branched C1-C12 alkyl radical; a linear or branched C2-C12 alkylene radical; —(CH2)n—C3-C6 cycloalkyl radical; —(CH2)nAr or —(CH2)nHet.; —(CH2)n—NH—CO—R; —(CH2)n—NH2; —(CH2)n—N(R,R′); —(CH2)n—NH—CO—OH; —(CH2)n—NH—CO—OR; —NH—(CH2)n—CO—OH; —NH—(CH2)n—CO—OR; R2 is —(CH2)n—Ar, Ar being such as above defined and being optionally substituted such as above defined; a linear or branched C1-C12 alkyl or C2-C12 alkylene radical with one or several double bonds; —(CH2)n—OH; —(CH2)n—OR; —(CH2)n—CO—Het; —(CH2)n—NH—CO—R; —(CH2)n—NH2; —(CH2)n—N(R,R′); —(CH2)n—CO—OH; —(CH2)n—CO—OR; a linear or branched C1-C12 alkyl radical; —(CH2)n—C(R)═CH—C(R)═CH2, R3 forms a phenyl or an heterocyclic condensed group with the two adjacent carbons of the pyrazinone residue, said condensed group being optionally substituted such as above defined for Ar and Het.; and/or condensed to a cyclohexyl or oxanyl group, in turn optionally substituted such as above defined for Ar; n is 0 or an integer from 1 to 5; or A is a substituted pyrazine of formula II wherein R4 is a —CO—NH—Ar radical, optionally substituted such as above defined; R5 forms a phenyl or heterocyclic group condensed to the two adjacent carbon groups of the pyrazine residue, said phenyl or heterocyclic group being optionally substituted such as above defined, and Ar being such as above defined with respect to formula I or A is a substituted pyridine group of formula III wherein, Ar and R2 are as above defined with respect to formula I.
US08809343B2 Pyrimidine derivative, preparation method and use thereof
A pyrimidine derivative and the preparation method and use thereof. The said pyrimidine derivative is a diaryl pyrimidine derivative or a diaryl benzo pyrimidine derivative which has the structure shown as the Formula I and IV. Present pyrimidine derivative can be used for the prevention or the treatment of HIV.
US08809338B2 1,2,3-triazole-based peptidomimetic integrin inhibitors for the diagnosis and therapy of tumors
The present invention refers to the field of chemical compounds bearing a 1,2,3-triazole ring of formula (I) and possessing guanidino and carboxylic groups or their isosteres, their preparation by Cu-catalyzed “click-chemistry”, and medical-diagnostic use in pathologies where angiogenesis is altered, for example pathologic conditions of tumor origin, tumor metastasis, osteoporosis, and rheumatoid arthritis.
US08809334B2 Therapeutic compositions containing macitentan
The invention relates to a product containing the compound of formula (I) below or a pharmaceutically acceptable salt of this compound, in combination with at least one compound having prostacyclin receptor (IP) agonist properties, or a pharmaceutically acceptable salt thereof.
US08809333B2 Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents
The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.
US08809332B2 Method for treating anxiety with a dosage form of besylate salts of zopiclone or eszopiclone
Besylate salts of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) are provided.
US08809329B2 Detection and treatment of schizophrenia
The present invention provides a method for diagnosing schizophrenia, and a schizophrenia diagnostic reagent or device for use in the method. The present invention further provides a therapeutic or ameliorating agent for schizophrenia, which is effective for the treatment or amelioration of schizophrenia. The therapeutic or ameliorating agent for schizophrenia contains a carbonyl scavenger or a carbonyl-modified protein formation inhibitor as an active ingredient. The method for diagnosing schizophrenia according to the present invention includes measuring at least one parameter in a subject, the parameter being selected from the group consisting of: (1) a genetic abnormality of glyoxalase I gene; (2) the expression level or activity of glyoxalase I in a biological sample; (3) the amount of a carbonyl compound or a carbonyl-modified protein that is a protein modified with the carbonyl compound; and (4) the amount of pyridoxal in a biological sample.
US08809326B2 Isoquinolinone Rho kinase inhibitors
Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compositions comprising such compounds, methods for using such compounds and processes for making such compounds.
US08809325B2 Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
Disclosed is a benzyl-oxathiazine derivative, as shown in Formula I, the derivative being substituted with adamantane or noradamantane: the variables of which are as described herein; also disclosed is a method of preparation and use of same.
US08809324B2 Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
The invention relates to the compounds of formula (I) and to the physiologically acceptable salts thereof. Said compounds are suitable e.g. for the treatment of hyperglycemia.
US08809315B2 Combination medicaments for treating bacterial infections
Use of a monobactam antibiotic of formula (I) wherein the oxyimino group i.e. >C═N—O— has Z-orientation, or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of a bacterial infection in combination with a carbapenem antibiotic or a pharmaceutically acceptable salt thereof.
US08809314B1 Cephalosporin compound
The cephalosporin compound of formula (I) is disclosed, which exhibits antibiotic activity against Gram-negative (e.g., Pseudomonas aeruginosa) and Gram-positive (e.g., methicillin-resistant Staphylococcus aureus) bacteria. Methods of manufacturing the compound of formula (I), and uses of the compound in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.
US08809312B2 Composition and method for affecting obesity and related conditions
A composition including an effective amount of a compound including manganese [III]tetrakis(4-benzoic acid)porphyrin (MnTBAP), derivatives or analogs thereof to induce a reduction in body weight of a mammal or to improve insulin sensitivity of an obese mammal. A method including introducing an effective amount of a compound including manganese [III]tetrakis(4-benzoic acid)porphyrin (MnTBAP), derivatives or analogs thereof to a mammal to induce a reduction in body weight or to induce an increase in metabolism or insulin sensitivity of the mammal.
US08809310B2 Use of rasagiline for the treatment of multiple system atrophy
Disclosed is a method for the treatment of Multiple System Atrophy comprising administering to a subject an amount of R(+)-N-propargyl-1-aminoindan or a pharmaceutically acceptable salt thereof.
US08809309B2 Use of 5α-androstane (alkyl)-3β,5,6β-triol in preparation of neuroprotective drugs
Disclosed is the use of 5α-androstane(alkyl)-3β,5,6β-triol in preparing neuroprotective drugs. The compound has significant protective effect against neuron injuries caused by cerebral ischemia, spinal cord ischemia or hypoxia and has no obvious toxic reaction within effective dose thereof.
US08809307B2 Pharmaceutical formulations containing corticosteroids for topical administration
The potency of a topical corticosteroid in a pharmaceutical formulation is maintained even when the concentration of the corticosteroid is substantially reduced by providing the corticosteroid in a formulation containing a liquid oil component that includes a dicarboxylic acid ester and/or a monocarboxylic acid ester.
US08809299B2 Combination therapy for the treatment of cancer
Described are methods and compositions for treating cancer that include a dopamine receptor (DR) antagonist such as thioridazine and a chemotherapeutic agent. Optionally, the chemotherapeutic agent is a DNA synthesis inhibitor such as cytarabine or a microtubule inhibitor such as paclitaxel or docetaxel. The methods and compositions are useful for the treatment of cancers such as acute myeloid leukemia.
US08809297B2 Anticancer composition
Disclosed is an anticancer composition, comprising an inhibitor against WIG1 and/or YPEL5 or against a protein encoded by the gene. A composition for screening an anticancer agent comprising a nucleic acid having a sequence complementary to an mRNA of WIG1 and/or YPEL5, or an antibody to a protein encoded by the gene is also provided. Also, a method is provided for screening an anticancer agent, which comprises: (A) quantitatively analyzing expression of WIG1 and/or YPEL5 at an mRNA or protein level in a tumor cell which is not treated with a candidate for an anticancer agent; (B) quantitatively analyzing expression of the gene at an mRNA or protein level in a tumor cell after treatment of the candidate for an anticancer agent; and (C) selecting the candidate if the expression level of the gene is increased in step (B), compared to step (A).
US08809296B2 Apoptosis inducer for cancer cell
The present invention revealed that by suppressing the expression of the WRN gene, the BLM gene, or the RecQ1 gene, which belong to the RecQ helicase family, apoptosis is induced in various cancer cells and their proliferation is suppressed. Compounds that suppress the expression of RecQ helicase family genes or the functions of RecQ helicase proteins are thought to have the activity of inducing apoptosis.
US08809293B2 Compositions and methods for inhibiting gene expression of hepatitis B virus
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a Hepatitis B Virus gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by Hepatitis B Virus infection using said pharmaceutical composition; and methods for inhibiting the expression of a Hepatitis B Virus gene in a cell.
US08809290B2 Methods and compositions to generate and control the effector profile of T cells by simultaneous loading and activation of selected subsets of antigen presenting cells
The present invention is directed to novel compositions that cause effective redirection of class I-immunity to Tc1 effectors, that take advantage of the unexpected loading of MHC I by peptide within IgG backbone combined with appropriate instruction of antigen presenting cells. Such compositions are able to transform a seemingly ineffective therapeutics into a highly effective one, associated with generation of class I-restricted cytolytic cells and IFN-γ, IL-2 producing T cells, further associated with protection against a highly virulent microbe or recovery from malignant tumoral process.
US08809288B2 Method for increasing immunoreactivity
The invention relates to an in vitro or ex vivo method for increasing the immunoreactivity of cells of the immune system, which were contacted with an antigen, said method comprising the reduction or inhibition of the Cbl-b function of said cells, thereby increasing the immunoreactivity of the cells towards the antigen.
US08809287B2 Compositions and methods for altering Wnt autocrine signaling
The present invention relates to compounds and methods for treating cancers in which the autocrine Wnt canonical signaling pathway is activated. In particular, there is provided a method for inhibiting growth of a tumor cell or sensitizing a cancer cell to treatment by contacting such a tumor cell with a compound that alters Wnt signaling. The compound that alters Wnt signaling can be a Wnt antagonist, a Wnt receptor antagonist, or a combination thereof.
US08809282B2 Method of reducing titers of antibodies specific for a therapeutic agent
The present invention relates, in general, to a method of treating patients undergoing enzyme replacement therapy (ERT) or other therapy involving the administration of a proteinaceous therapeutic agent as well gene replacement therapy with non-viral or viral vectors, or other therapeutic modality or modalities, used alone or in combination, which involve the administration of exogenous substances for potential therapeutic benefit, including, but not limited to DNA vaccines, siRNA, splice-site switching oligomers (SSOs) as well as RNA-based nanoparticles (RNPs) and nanovaccines. The invention further relates to compounds and compositions suitable for use in such methods.
US08809277B2 Dual secured therapeutic peptide delivery system
A delivery system is described that includes a polymer network that can incorporate a therapeutic peptide for targeted delivery to a cell, e.g., a cancer cell. The polymer network can secure the therapeutic peptide via two different mechanisms. First, a polymer of the network can interact with the therapeutic peptide via charge/charge interaction to form a complex with the peptide, thereby holding the peptide within the network. Second, the polymer network can be crosslinked, providing another level of securement for holding the therapeutic peptide within the network. The two levels of securement can be reversible, and following delivery of the network to the interior of a targeted cell reversal of the securement mechanisms can release the therapeutic peptide within the cell.
US08809275B2 Peptoids and methods for treating alzheimer's disease
Provided herein are peptoids capable of inhibiting or reversing amyloid β (Aβ) fibril or plaque production. The peptoids form a helical structure with three monomers per helical turn and have at least two monomers with a side-chain having an arylalkyl group having the same chirality positioned such that the side-chains are on the same side of the peptoid. Also provided are methods of using the peptoids to inhibit or reverse aggregation of Aβ and methods of treating subjects with Alzheimer's disease (AD) or slowing the progression of AD.
US08809271B2 Therapeutic agent preparations comprising liraglutide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.
US08809270B2 Method for reducing cardiovascular morbidity and mortality in prediaetic patients and patients with type 2 diabetes
This invention relates to a method of reducing cardiovascular morbidity and mortality in a prediabetic or Type 2 Diabetes patient population. The method comprises administering an effective dosage of a long acting insulin, preferably insulin glargine, to a prediabetic or Type 2 Diabetes patient.
US08809269B2 Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.
US08809263B2 Anti-infective hydroxy-phenyl-benzoates and methods of use
The invention provides a method for preventing or treating a disease caused by an extracellular microorganism, said method comprising systemically administering to a subject in need thereof a prophylactically or therapeutically effective amount of a salicylic acid (SAL) or a SAL analogue. The extracellular microorganism can be of the bacterial genus Staphylococcus, for example, Staphylococcus aureus. The extracellular microorganism can be a strain that is resistant to at least one antibiotic. The strain can be selected from the group consisting of methycillin-resistant Staphylococcus aureus (MRSA), vancomycin-intermediate Staphylococcus aureus (VISA) and vancomycin-resistant Staphylococcus aureus (VRSA). The invention also provides a method for preventing or treating an infectious disease caused by of methycillin-resistant Staphylococcus aureus (MRSA), vancomycin-intermediate Staphylococcus aureus (VISA) or vancomycin-resistant Staphylococcus aureus (VRSA), comprising systemically coadministering in a synergistic combination to a subject in need thereof prophylactically or therapeutically effective amounts, individually or collectively, of a salicylic acid (SAL) or a SAL analogue and at least one additional antimicrobial agent, for example, vancomycin and/or linezolid.
US08809257B2 Compositions and methods for promoting wound healing and tissue regeneration
Provided herein are compositions and methods for use in promoting wound healing and tissue regeneration following tissue injury in a subject.
US08809250B2 Concentrated film delivery systems
A water soluble strip that includes a carrier film that include water soluble polymer, one or more actives and one or more agents such as heat forming agent and/or degrading accelerator. The water soluble strip can optionally include other additives. The actives includes antimicrobial agent, cleaning agent and/or surfactant. The water soluble strip can include other materials. The heat forming agent and/or degrading accelerator, when used, are designed facilitate in degrading or dissolving the water soluble strip and/or increase the activity of the one or more actives. The water soluble film can be used for a variety of applications such as a hard surface cleaning strip, dishwashing strip, laundry cleaning strip, stop removing strip, drain unclogging strip, toilet bowl cleaning strip and the like. The water soluble strip eliminates the need to purchase and store numerous containers and/or heavy containers of cleaner that take up large amounts of shelf space.
US08809247B2 Cleaning composition and method for cleaning substrate for electronic device
A cleaning composition which is capable of removing both organic soiling and particulate soiling adhered to a substrate for an electronic device with a high degree of cleanliness, and which also has minimal impact on the environment, as well as a method of cleaning a substrate for an electronic device. The present invention relates to a cleaning composition used for cleaning a substrate for an electronic device including a water-soluble salt (A) containing a transition metal, a chelating agent (B) and a peroxide (C), wherein the amount of the chelating agent (B) is not less than 0.5 molar equivalents relative to the amount of the water-soluble salt (A) containing a transition metal.
US08809239B2 Detection of target nucleic acid sequences by PTO cleavage and extension assay
The present invention relates to the detection of a target nucleic acid sequence by a PTOCE (PTO Cleavage and Extension) assay. The present invention detects a target nucleic acid sequence in which the PTO (Probing and Tagging Oligonucleotide) hybridized with the target nucleic acid sequence is cleaved to release a fragment and the fragment is hybridized with the CTO (Capturing and Templating Oligonucleotide) to form an extended duplex, followed by detecting the presence of the extended duplex. The extended duplex provides signals (generation, increase, extinguishment or decrease of signals) from labels indicating the presence of the extended duplex and has adjustable Tm value, which are well adoptable for detection of the presence of the target nucleic acid sequence.
US08809234B1 Drift reduction compositions for agricultural use
The present disclosure relates generally to the field of agricultural chemicals and, more particularly, to compositions which can be added to agricultural chemicals for the purpose of improving efficacy and reducing drift of sprayed chemicals away from target areas. Further disclosed are processes for preparing combination water conditioning adjuvant and drift reduction compositions as well as methods of drift reduction utilizing such compositions.
US08809232B2 Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and halosulfuron, pyrazosulfuron and esprocarb
Provided herein are synergistic herbicidal compositions containing and methods of controlling undesirable vegetation utilizing (a) a compound of formula (I): or an agriculturally acceptable salt or ester thereof and (b) halosulfuron-methyl, pyrazosulfuron-ethyl or esprocarb, or an agriculturally acceptable derivative thereof. The compositions and methods provided herein provide control of undesirable vegetation, e.g., in direct-seeded, water-seeded and transplanted rice, cereals, wheat, barley, oats, rye, sorghum, corn or maize, sugarcane, sunflower, oilseed rape, canola, sugar beet, soybean, cotton, pineapple, oilseed rape, vegetables, pastures, grasslands, rangelands, fallowland, turf, tree and vine orchards, aquatics, plantation crops, vegetables, industrial vegetation management (IVM) or rights of way (ROW).
US08809231B2 Method for making alkali activated carbon
A method for activating carbon via alkali activation processes includes the introduction of water vapor during the activation phase to control the formation of highly reactive by-products. The method includes heating the mixture of a carbon-containing first material and a alkali-containing second material, introducing water vapor at a first threshold temperature and stopping water vapor introduction at a second threshold temperature. The activated carbon material is suitable for carbon-based electrodes and for use in high energy density devices.
US08809225B2 Iron-based fischer-tropsch catalyst
An iron-based Fischer-Tropsch catalyst comprising magnetite and characterized by integrable X-ray diffraction reflections corresponding to (311), (511), (440), and (400), such that the relative intensity of the (400) reflection to the (300) reflection is less than about 39%. A method of preparing an activated iron-based Fischer-Tropsch catalyst by providing a precipitated catalyst comprising oxides including at least iron oxide; and activating the precipitated catalyst to provide the activated iron-based Fischer-Tropsch catalyst, wherein activating the precipitated catalyst comprises exposing the precipitated catalyst to an activation gas and increasing the temperature from a first temperature to a second temperature at a ramp rate, whereby the ratio of the intensity of the (400) reflection of the activated iron-based Fischer-Tropsch catalyst to the intensity of the (311) reflection thereof is less than 38%.
US08809224B2 Catalyst for the decomposition of nitrogen protoxide
A catalyst for removing nitrogen protoxide from gas mixtures which contain it, comprising mixed oxides of cobalt, manganese and rare earth metals having composition expressed as percentage by weight of CoO, MnO and transition metal oxide in the lowest state of valence as follows: MnO 38-56%, CoO 22-30%, rare earth metal oxide 22-32%.
US08809218B2 Zeolite-palladium complex, method for producing the same, catalyst containing the complex, and method for producing a coupling compound by using the catalyst
There is provided a substance having much higher catalytic activity for a Suzuki-Miyaura coupling reaction than conventional heterogenous catalysts. The present invention provides a zeolite-palladium complex including USY-zeolite and Pd supported on the USY-zeolite, the Pd having a Pd—Pd coordination number of 4 or less and an oxidation number of 0.5 or less.
US08809216B2 Catalyst for converting acid-containing inferior crude oil and process for making and using the same
The present invention relates to a catalyst for converting inferior acid-containing crude oil. Based on the total amount of the catalyst, said catalyst comprises from 1 to 50 wt % of a mesopore material, from 1 to 60 wt % of molecular sieves and from 5 to 98 wt % of thermotolerant inorganic oxides and from 0 to 70 wt % of clays. Said mesopore material is an amorphous material containing alkaline earth oxide, silica and alumina, and has an anhydrous chemical formula of (0-0.3)Na2O.(1-50)MO.(6-58)Al2O3.(40-92)SiO2, based on the weight percent of the oxides, wherein M is one or more selected from Mg, Ca and Ba. Said mesopore material has a specific surface area of 200-400 m2/g, a pore volume of 0.5-2.0 ml/g, an average pore diameter of 8-20 nm, and a most probable pore size of 5-15 nm. The catalyst provided in the present invention is suitable for the catalytic conversion of crude oil having a total acid number of greater than 0.5 mgKOH/g and for the removal of organic acids, carbon residues and metals in crude oil, and thus has very good economic benefits.
US08809215B2 Catalysts
A process for regenerating a spent cobalt Fischer-Tropsch synthesis catalyst includes subjecting a spent particulate cobalt Fischer-Tropsch synthesis catalyst sequentially to a dewaxing treatment, an oxidation treatment at a pressure of 4 to 30 bar(a) and a reduction treatment, thereby regenerating the catalyst.
US08809209B2 Fluorinated copolymers
A stain resistant, oil and water repellent composition comprising a copolymer prepared from fluorinated methacrylate, carbonate methacrylate, and methacrylic acid or salt thereof, a method of providing stain resistance, oil and water repellency to substrates, and a treated substrate.
US08809208B2 Nano-tube thermal interface structure
A structure, comprising: a semiconductor structure having an electrically and thermally conductive layer disposed on one surface of the semiconductor structure; an electrically and thermally conductive heat sink; a electrically and thermally conductive carrier layer; a plurality of electrically and thermally nano-tubes, a first portion of the plurality of nano-tubes having proximal ends disposed on a first surface of the carrier layer and a second portion of the plurality of nano-tubes having proximal ends disposed on an opposite surface of the carrier layer; and a plurality of electrically and thermally conductive heat conductive tips disposed on distal ends of the plurality of nano-tubes, the plurality of heat conductive tips on the first portion of the plurality of nano-tubes being attached to the conductive layer, the plurality of heat conductive tips on the second portion of the plurality of nano-tubes being attached to the heat sink.
US08809207B2 Pattern-forming method and method for manufacturing semiconductor device
A pattern-forming method for forming a predetermined pattern serving as a mask when etching film on a substrate includes the steps of: an organic film pattern-forming step for forming an organic film pattern on a film to be processed; forming a silicon nitride film on the organic film pattern; etching the silicon nitride film so that the silicon nitride film remains only on the lateral wall sections of the organic film pattern; and removing the organic film, thereby forming the predetermined silicon nitride film pattern on the film to be processed on a substrate. With the temperature of the substrate maintained at no more than 100° C., the film-forming step excites a processings gas and generates a plasma, performs plasma processing with the plasma, and forms a silicon nitride film having stress of no more than 100 MPa.
US08809206B2 Patterned dummy wafers loading in batch type CVD
A method for semiconductor device fabrication is provided. The present invention is directed towards using at least one patterned dummy wafer along with one or more product wafers in a film deposition system to create a sidewall layer thickness variation that is substantially uniform across all product wafers. The at least one patterned dummy wafer may have a high density patterned substrate surface with a topography that is different from or substantially similar to a topography of the one or more product wafers. Furthermore, in a batch type Chemical Vapor Deposition (CVD) system, the at least one patterned dummy wafer may be placed near a gas inlet of the CVD system. At least one patterned dummy wafer may be placed near an exhaust of the CVD system. Additionally, the patterned dummy wafers may be reusable in subsequent film deposition processes.
US08809193B2 Method for the formation of Co film and method for the formation of Cu interconnection film
A Co film is formed by supplying cobalt alkylamidinate, and a combined gas containing H2 gas with at least one member selected from the group consisting of NH3, N2H4, NH(CH3)2, N2H3CH, and N2 as a reducing gas, or at least one gas selected from the group consisting of NH3, N2H4, NH(CH3)2, N2H3CH, and N2 as a reducing gas, on the surface of a base material, which consists of an SiO2 film or a barrier film serving as a primary layer. A Cu interconnection film is formed on the surface of the Co film.
US08809184B2 Methods of forming contacts for semiconductor devices using a local interconnect processing scheme
One method disclosed herein includes forming a plurality of source/drain contacts that are conductively coupled to a source/drain region of a plurality of transistor devices, wherein at least one of the source/drain contacts is a local interconnect structure that spans the isolation region and is conductively coupled to a first source/drain region in a first active region and to a second source/drain region in a second active region, and forming a patterned mask layer that covers the first and second active regions and exposes at least a portion of the local interconnect structure positioned above an isolation region that separates the first and second active regions. The method further includes performing an etching process through the patterned mask layer to remove a portion of the local interconnect structure, thereby defining a recess positioned above a remaining portion of the local interconnect structure, and forming an insulating material in the recess.
US08809177B2 Semiconductor device and method for manufacturing the same
A semiconductor device and a method for manufacturing the same are provided. The semiconductor device includes a gate pattern formed by patterning a tunnel insulating layer, a conductive film for a floating gate, a dielectric film, a conductive film for a control gate, and a gate metal film sequentially formed on a semiconductor substrate; a first barrier film formed on side walls of the gate metal film; and a second barrier film formed on an upper surface of the gate metal film.
US08809173B1 Fin field-effect transistors and fabrication method thereof
A method is provided for fabricating a fin field-effect transistor. The method includes providing a semiconductor substrate; and forming a plurality of fins on top of the semiconductor substrate. The method also includes forming isolation structures between adjacent fins; and forming doping sidewall spacers in top portions of the isolation structures near the fins. Further, the method includes forming a punch-through stop layer at the bottom of each of the fins by thermal annealing the doping sidewall spacers; and forming a high-K metal gate on each of the fins.
US08809164B2 Method of large-area circuit layout recognition
Methods for detecting the physical layout of an integrated circuit are provided. The methods of the present disclosure allow large area imaging of the circuit layout without requiring tedious sample preparation techniques. The imaging can be performed utilizing low-energy beam techniques such as scanning electron microscopy; however, more sophisticated imaging techniques can also be employed. In the methods of the present disclosure, spalling is used to remove a portion of a semiconductor layer including at least one semiconductor device formed thereon or therein from a base substrate. In some cases, a buried insulator layer that is located beneath a semiconductor layer including the at least one semiconductor device can be completely or partially removed. In some cases, the semiconductor layer including the at least one semiconductor device can be thinned. The methods improve the detection quality that the buried insulator layer and a thick semiconductor layer can reduce.
US08809162B2 Method for manufacturing a semiconductor device comprising a guard ring between a cell region and a peripheral region
A semiconductor device including a cell region and a peripheral region, the semiconductor device comprising: a guard ring region provided between the cell region and the peripheral region, the guard ring region having a barrier structure.
US08809160B2 Methods for forming high-K crystalline films and related devices
This disclosure provides a method of fabricating a semiconductor stack and associated device, such as a capacitor or DRAM cell. In such a device, a high-K zirconia-based layer may be used as the primary dielectric together with a relatively inexpensive metal electrode based on titanium nitride. To prevent corruption of the electrode during device formation, a thin barrier layer can be used seal the electrode prior to the use of a high temperature process and a (high-concentration or dosage) ozone reagent (i.e., to create a high-K zirconia-based layer). In some embodiments, the barrier layer can also be zirconia-based, for example, a thin layer of doped or un-doped amorphous zirconia. Fabrication of a device in this manner facilitates formation of a device with dielectric constant of greater than 40 based on zirconia and titanium nitride, and generally helps produce less costly, increasingly dense DRAM cells and other semiconductor structures.
US08809157B2 Methods of forming a programmable region that comprises a multivalent metal oxide portion and an oxygen containing dielectric portion
A method of forming a memory cell includes forming one of multivalent metal oxide material or oxygen-containing dielectric material over a first conductive structure. An outer surface of the multivalent metal oxide material or the oxygen-containing dielectric material is treated with an organic base. The other of the multivalent metal oxide material or oxygen-containing dielectric material is formed over the treated outer surface. A second conductive structure is formed over the other of the multivalent metal oxide material or oxygen-containing dielectric material.
US08809152B2 Germanium oxide free atomic layer deposition of silicon oxide and high-k gate dielectric on germanium containing channel for CMOS devices
A semiconductor device including a germanium containing substrate including a gate structure on a channel region of the semiconductor substrate. The gate structure may include a silicon oxide layer that is in direct contact with an upper surface of the germanium containing substrate, at least one high-k gate dielectric layer in direct contact with the silicon oxide layer, and at least one gate conductor in direct contact with the high-k gate dielectric layer. The interface between the silicon oxide layer and the upper surface of the germanium containing substrate is substantially free of germanium oxide. A source region and a drain region may be present on opposing sides of the channel region.
US08809148B2 EEPROM-based, data-oriented combo NVM design
A nonvolatile memory device has a combination of FLOTOX EEPROM nonvolatile memory arrays. Each FLOTOX-based nonvolatile memory array is formed of FLOTOX-based nonvolatile memory cells that include at least one floating gate tunneling oxide transistor such that a coupling ratio of the control gate to the floating gate of the floating gate tunneling oxide transistor is from approximately 60% to approximately 70% and a coupling ratio of the floating gate to the drain region of the floating gate tunneling oxide transistor is maintained as a constant of is from approximately 10% to approximately 20% and such that a channel length of the channel region is decreased such that during the programming procedure a negative programming voltage level is applied to the control gate and a moderate positive programming voltage level is applied to the drain region to prevent the moderate positive programming voltage level from exceeding a drain-to-source breakdown voltage.
US08809147B2 Dual conducting floating spacer metal oxide semiconductor field effect transistor (DCFS MOSFET) and method to fabricate the same
Dual Conducting Floating Spacer Metal Oxide Semiconductor Field Effect Transistors (DCFS MOSFETs) and methods for fabricate them using a process that is compatible with forming conventional MOSFETs are disclosed. A DCFS MOSFET can provide multi-bit storage in a single Non-Volatile Memory (NVM) memory cell. Like a typical MOSFET, a DCFS MOSFET includes a control gate electrode on top of a gate dielectric-silicon substrate, thereby forming a main channel of the device. Two electrically isolated conductor spacers are provided on both sides of the control gate and partially overlap two source/drain diffusion areas, which are doped to an opposite type to the conductivity type of the substrate semiconductor. The DCFS MOSFET becomes conducting when a voltage that exceeds a threshold is applied at the control gate and is coupled through the corresponding conducting floating spacer to generate an electrical field strong enough to invert the carriers near the source junction. By storing charge in the two independent conducting floating spacers, DCFS MOSFET can have two independent sets of threshold voltages associated with the source junctions.
US08809145B2 Semiconductor cells, arrays, devices and systems having a buried conductive line and methods for forming the same
Semiconductor arrays including a plurality of access devices disposed on a buried conductive line and methods for forming the same are provided. The access devices each include a transistor having a source region and drain region spaced apart by a channel region of opposite dopant type and an access line associated with the transistor. The access line may be electrically coupled with one or more of the transistors and may be operably coupled to a voltage source. The access devices may be formed in an array on one or more conductive lines. A system may be formed by integrating the semiconductor devices with one or more memory semiconductor arrays or conventional logic devices, such as a complementary metal-oxide-semiconductor (CMOS) device.
US08809141B2 High performance CMOS transistors using PMD liner stress
A silicon nitrate layer (110) is formed over a transistor gate (40) and source and drain regions (70). The as-formed silicon nitride layer (110) comprises a first tensile stress and a high hydrogen concentration. The as-formed silicon nitride layer (110) is thermally annealed converting the first tensile stress into a second tensile stress that is larger than the first tensile stress. Following the thermal anneal, the hydrogen concentration in the silicon nitride layer (110) is greater than 12 atomic percent.
US08809138B2 Method of forming a semiconductor device
A semiconductor device is disclosed. In one aspect, the device has a first and second active layer on a substrate, the second active layer having a higher bandgap than the first active layer, being substantially Ga-free and including at least Al. The device has a gate insulating layer on a part of the second active layer formed by thermal oxidation of a part of the second active layer. The device has a gate electrode on at least a part of the gate insulating layer and a source electrode and drain electrode on the second active layer. The device has, when in operation and when the gate and source electrode are at the same voltage, a two-dimensional electron gas layer between the first and second active layer only outside the location of the gate electrode and not at the location of the gate electrode.
US08809137B2 Leakage barrier for GaN based HEMT active device
An improved HEMT formed from a GaN material system is disclosed which has reduced gate leakage current and eliminates the problem of current constrictions resulting from deposition of the gate metal over the step discontinuities formed over the gate mesa. One or more GaN based materials are layered and etched to form a gate mesa with step discontinuities defining source and drain regions. In order to reduce the leakage current, the step discontinuities are back-filled with an insulating material, such as silicon nitride (SiN), forming a flat surface relative to the source and drain regions, to enable to the gate metal to lay flat. By back-filling the source and drain regions with an insulating material, leakage currents between the gate and source and the gate and drain are greatly reduced. In addition, current constrictions resulting from the deposition of the gate metal over a step discontinuity are virtually eliminated.
US08809136B2 Semiconductor device and method for manufacturing the same
A semiconductor device having a source electrode and a drain electrode formed over a semiconductor substrate, a gate electrode formed over the semiconductor substrate and disposed between the source electrode and the drain electrode, a protection film made of an insulating material and formed between the source electrode and the gate electrode and between the drain electrode and the gate electrode, and a gate side opening formed at least in one of a portion of the protection film-between the source electrode and the gate electrode and a portion of the protection film between the drain electrode and the gate electrode and disposed away from all of the gate electrode, the source electrode and the drain electrode.
US08809134B2 Semiconductor structure and method for manufacturing the same
A method of manufacturing a semiconductor structure, which comprises the steps of: providing a substrate, forming a fin on the substrate, which comprises a central portion for forming a channel and an end portion for forming a source/drain region and a source/drain extension region; forming a gate stack to cover the central portion of the fin; performing light doping to form a source/drain extension region in the end portion of the fin; forming a spacer on sidewalls of the gate stack; performing heavy doping to form a source/drain region in the end portion of the fin; removing at least a part of the spacer to expose at least a part of the source/drain extension region; forming a contact layer on an upper surface of the source/drain region and an exposed area of the source/drain extension region. Correspondingly, the present invention also provides a semiconductor structure. By forming a thin contact layer in the source/drain extension region, the present invention can not only effectively reduce the contact resistance of the source/drain extension region, but also effectively control the junction depth of the source/drain extension region by controlling the thickness of the contact layer, thereby suppressing the short channel effect.
US08809132B2 Capping layers for metal oxynitride TFTs
A capping layer may be deposited over the active channel of a thin film transistor (TFT) in order to protect the active channel from contamination. The capping layer may affect the performance of the TFT. If the capping layer contains too much hydrogen, nitrogen, or oxygen, the threshold voltage, sub threshold slope, and mobility of the TFT may be negatively impacted. By controlling the ratio of the flow rates of the nitrogen, oxygen, and hydrogen containing gases, the performance of the TFT may be optimized. Additionally, the power density, capping layer deposition pressure, and the temperature may also be controlled to optimize the TFT performance.
US08809131B2 Replacement gate fin first wire last gate all around devices
In one aspect, a method of fabricating a nanowire FET device includes the following steps. A wafer is provided. At least one sacrificial layer and silicon layer are formed on the wafer in a stack. Fins are patterned in the stack. Dummy gates are formed over portions of the fins which will serve as channel regions, and wherein one or more portions of the fins which remain exposed will serve as source and drain regions. A gap filler material is deposited surrounding the dummy gates and planarized. The dummy gates are removed forming trenches in the gap filler material. Portions of the silicon layer (which will serve as nanowire channels) are released from the fins within the trenches. Replacement gates are formed within the trenches that surround the nanowire channels in a gate all around configuration. A nanowire FET device is also provided.
US08809128B2 Methods and apparatus for layout of three dimensional matrix array memory for reduced cost patterning
The present invention provides apparatus, methods, and systems for a memory layer layout for a three-dimensional memory. The memory layer includes a plurality of memory array blocks; a plurality of memory lines coupled to the memory array blocks; and a plurality of zia contact areas for coupling the memory layer to other memory layers in a three-dimensional memory. The memory lines extend from the memory array blocks and are formed using a sidewall defined process. The memory lines have a half pitch dimension smaller than the nominal minimum feature size capability of a lithography tool used in forming the memory lines. The zia contact areas have a dimension that is approximately four times the half pitch dimension of the memory lines. The memory lines are arranged in a pattern adapted to allow a single memory line to intersect a single zia contact area and to provide area between other memory lines for other zia contact areas. Numerous additional aspects are disclosed.
US08809122B2 Method of manufacturing flip chip package
A method of manufacturing a flip chip package includes: providing a board including a conductive pad disposed inside a mounting region of the board on which the electronic device is to be mounted, and a connection pad disposed outside the mounting region; forming a resin layer on the board; forming a trench by removing a part of the resin layer or forming an uneven portion at a portion of a surface of the resin layer; forming, on the trench or uneven portion, a dam member preventing leakage of an underfill between the mounting region and the connection pad; and mounting the electronic device on the mounting region.
US08809121B2 Singulation of IC packages
A method of dividing a two dimensional array of encapsulated integrated circuits into individual integrated circuit packages uses a first series of parallel cuts (32) extending fully through the leadframe (16) and encapsulation layer (14), and defining rows of the array. The cuts terminate before the beginning and end of the rows such that the integrity of the array is maintained by edge portions (34) at the ends of the rows. After plating contact pads (18), a second series of parallel cuts (36) is made extending fully through the leadframe (16) and encapsulation layer (14). This separates the array into columns thereby providing singulation of packages between the edge portions (34).
US08809117B2 Packaging process tools and packaging methods for semiconductor devices
Packaging process tools and packaging methods for semiconductor devices are disclosed. In one embodiment, a packaging process tool for semiconductor devices includes a mechanical structure including a frame. The frame includes a plurality of apertures adapted to retain a plurality of integrated circuit dies therein. The frame includes at least one hollow region.
US08809114B2 Memory cell that employs a selectively grown reversible resistance-switching element and methods of forming the same
A method of forming a memory cell is provided that includes forming a steering element above a substrate, forming a material layer on the substrate, patterning and etching the material layer, and oxidizing the patterned and etched material layer to form a reversible resistance-switching material. Numerous other aspects are provided.
US08809112B2 Selectively etching of a carbon nano tubes (CNT) polymer matrix on a plastic substructure
The present invention refers to a method for selectively structuring of a polymer matrix comprising CNT (carbon nano tubes) on a flexible plastic substructure. The method also includes a suitable etching composition, which allows to proceed the method in a mass production.
US08809105B2 Method of processing a semiconductor assembly
A method for processing a semiconductor assembly is presented. The method includes thermally processing a semiconductor assembly in a non-oxidizing atmosphere at a pressure greater than about 10 Torr. The semiconductor assembly includes a semiconductor layer disposed on a support, and the semiconductor layer includes cadmium and sulfur.
US08809099B2 Light sensor having IR cut interference filter with color filter integrated on-chip
Techniques are described to furnish a light sensor that includes a patterned IR interference filter integrated with a patterned color pass filter. In one or more implementations, the light sensor includes a substrate having a surface. An IR interference filter configured to block infrared light is disposed over the surface of the substrate. The light sensor also includes one or more color pass filters placed above or below the IR interference filter. The color pass filters are configured to filter visible light to pass light in a limited spectrum of wavelengths to the one or more photodetectors.
US08809094B2 Method of manufacturing solid-state image sensor
A method of manufacturing a solid-state image sensor, comprising preparing a semiconductor substrate including a photoelectric converter and an insulating film which includes an opening and is formed in a region above the photoelectric converter, depositing a material having a refractive index higher than the insulating film in the opening, and annealing the material deposited in the opening by irradiating the material with one of light and radiation, wherein a light waveguide which is configured to guide an incident light to the photoelectric converter is formed through the depositing and the annealing.
US08809084B2 Laser induced thermal imaging method and a method of fabricating organic light emitting display
A laser induced thermal imaging method includes preparing a donor element and a substrate; facing a transfer layer of the donor element to the substrate and then patterning the transfer layer onto the substrate; and annealing the patterned substrate.
US08809082B2 Method for producing lamps
A method for producing luminous means proposes providing a carrier serving as a heat sink, said carrier comprising a planar chip mounting region. The planar chip mounting region is structured for the purpose of producing a first partial region and at least one second partial region. In this case, the first partial region has a solder-repellent property after structuring. Afterward, a solder is applied to the planar chip mounting region, such that said solder wets the at least one second partial region. At least one optoelectronic body is fixed into the at least one second partial region with the solder at the carrier. Finally, contact-connections are formed for the purpose of feeding electrical energy to the optoelectronic luminous body.
US08809081B2 Electronic device and method of manufacturing an electronic device
An electronic device comprising at least one die stack having at least a first die (D1) comprising a first array of light emitting units (OLED) for emitting light, a second layer (D2) comprising a second array of via holes (VH) and a third die (D3) comprising a third array of light detecting units (PD) for detecting light from the first array of light emitting units (OELD) is provided. The second layer (D2) is arranged between the first die (D1) and the third die (D3). The first, second and third array are aligned such that light emitted from the first array of light emitting units (OLED) passed through the second array of via holes (VH) and is detected by the third array of light detecting units (PD). The first array of light emitting units and/or the third array of light detecting units are manufactured based on standard semiconductor manufacturing processes.
US08809080B2 Electronic assembly
An electronic assembly includes a first substrate and a second substrate, a hole through the first substrate, the second substrate having a trace with an indentation, an electronic device mounted over the indentation in the trace, and the first substrate is attached to the second substrate such that the electronic device is positioned within the hole through the first substrate.
US08809075B2 Method for applying liquid material utilizing capillary phenomenon
The method for filling a liquid material, and the apparatus and the program make it possible, without changing a moving speed of an ejection device, to correct a change in ejection amount and to stabilize an application shape. The method fills a liquid material into a gap between a substrate and a work by using the capillary action. The method includes the steps of: generating an application pattern consisting of a plurality of application areas continuous to one another; assigning a plurality of ejection cycles, each obtained by combining the number of ejection pulses and the number of pause pulses at a predetermined ratio therebetween, to each of the application areas; and measuring an ejection amount at correction intervals and calculating a correction amount for the ejection amount.
US08809072B2 Sub-resolution assist feature arranging method and computer program product and manufacturing method of semiconductor device
According to a sub-resolution assist feature arranging method in embodiments, it is selected which of a rule base and a model base is set for which pattern region on pattern data corresponding to a main pattern as a type of the method of arranging the sub-resolution assist feature for improving resolution of the main pattern formed on a substrate. Then, the sub-resolution assist feature by the rule base is arranged in a pattern region set as the rule base and the sub-resolution assist feature by the model base is arranged in a pattern region set as the model base.
US08809071B2 Method for immobilizing biologic molecules on solid surfaces
The invention provides a method for immobilization of biological molecules such as nucleic acids, peptides and proteins onto the surface of a glass or plastic solid support.
US08809070B2 Dispensing method
A dispensing method which dispenses a first liquid contained in a first vessel which stores the first liquid and a second liquid to introduce the first liquid into a second vessel by using a tube.
US08809063B2 Fluorescent carbazole oligomers nanofibril materials for vapor sensing
A fluorescence based sensor (10) is disclosed and described. The sensor (10) can include nanofibril materials (12) fabricated from a linear carbazole oligomer and a fluorescence detector (14). The linear carbazole oligomer can have the formula (I) wherein n is 3 to 9, R are independently selected amine sidegroups, and at least one, but not all, R is a C1 to C14 alkyl. The carbazole-based fluorescence based sensors (10) can be particularly suitable for detection of explosives and volatile nitro compounds.
US08809062B2 Method and apparatus for fractionation-based chemical analyses
A method (100) for analyzing chemicals includes fractionating a complex sample into at least two sample portions that each includes potions of two polypeptides though in different concentration ratios, digesting and performing LC/MS on each of the sample portions (110, and associating precursor ions observed via LC/MS with their corresponding polypeptide in response to LC/MS provided intensity data (170). A set of precursor ions that has substantially similar intensity ratios in both sample portions is determined to be associated with the same polypeptide.
US08809061B2 Liquid living body phantom and method of making the same
A living body phantom according to the present invention, which is used as a testing sample in a prepared slide in estimating the performance of a microscope objective lens with the image of the testing sample in the prepared slide acquired by an imaging means via the microscope objective lens and with optical characteristics obtained from the image of the testing sample, includes a non-gel-like solution at least including: a solvent which at least includes water, a refractive index adjustment agent, and a scattering body or which at least includes a refractive index adjustment agent and a scattering body; and a thickener.
US08809058B2 Helper virus-free AAV production
A method for the production of adeno-associated virus stocks and recombinant adeno-associated virus stocks that are substantially free of contaminating helper virus is described. The method utilizes transfection with helper virus vectors to replace the infection with helper virus used in the conventional method.
US08809057B2 Methods of evaluating gene expression levels
Described herein are methods of evaluating the expression levels of DNA parts encoding proteins in test circuits. In particular, the methods disclosed herein are useful to evaluate the expression of an output protein regulated by a regulatory protein-genetic element pair.
US08809055B2 Process for concentration of a polypeptide
The present invention comprises a method of concentrating a composition comprising a polypeptide of interest and the use of such a concentrated composition for the treatment of diseases in mammals, in particular by subcutaneous injection.
US08809054B2 Cell-culture-bag
The present invention is directed to a method to expand adherent cells comprising addition of adherent cells to an expansion container comprising microcarriers and culture medium; removing medium from the expansion container through a 8-20 mm filter; allowing cells to attach to microcarriers and keeping the expansion container in motion with an angle of between 30 to 90° and −30 to −90°. The present invention is also directed to a device suitable in the method. The advantage of the present invention is that fewer steps are needed to expand adherent cells, including stem cells like MSC opening the way for the use of autologeous and allogenous stem cell therapy. In addition, contamination risk is limited since the present invention may be carried out in a closed, disposable system.
US08809053B2 Cardiomyocyte culture support
Methods and reagents are described for myocardial regenerative therapy using cardiomyocytes that are cultured ex vivo to have a controlled orientation of beating. This is achieved by growing the cardiomyocytes on a culture support that is coated with a polymerizable liquid crystal which is oriented so as to be in a liquid crystal phase state prior to curing with ionizing radiation or ultraviolet rays.
US08809051B2 Transgenic mammals having human Ig loci including plural VH and Vκ regions and antibodies produced therefrom
The present invention relates to transgenic non-human animals that are engineered to contain human immunoglobulin gene loci. In particular, animals in accordance with the invention possess human Ig loci that include plural variable (VH and Vκ) gene regions. Advantageously, the inclusion of plural variable region genes enhances the specificity and diversity of human antibodies produced by the animal. Further, the inclusion of such regions enhances and reconstitutes B-cell development to the animals, such that the animals possess abundant mature B-cells secreting extremely high affinity antibodies.
US08809048B2 Plasmid vector
The object is to provide a technique for modifying a bacterium belonging to the genus Kocuria through genetic engineering for industrially effectively utilizing the bacterium belonging to the genus Kocuria. The above object can be achieved by providing a cyclic plasmid, which has a replication region comprising the base sequence of a DNA-binding protein-like protein gene, the base sequence of a replicase-like protein gene, and the base sequence represented by SEQ ID NO:45, and is autonomously replicable in bacteria. As an example of the aforesaid plasmid, a plasmid containing a base sequence represented by SEQ ID NO:3 or 4 which originates in Kocuria sp. MBE131 strain (FERM P-21885) can be cited.
US08809044B2 Highly efficient gas permeable devices and methods for culturing cells
This invention relates to methods and devices that improve cell culture efficiency. They include the use of gas permeable culture compartments that reduce the use of space while maintaining uniform culture conditions, and are more suitable for automated liquid handling. They include the integration of gas permeable materials into the traditional multiple shelf format to resolve the problem of non-uniform culture conditions. They include culture devices that use surfaces comprised of gas permeable, plasma charged silicone and can integrate traditional attachment surfaces, such as those comprised of traditional tissue culture treated polystyrene. They include culture devices that integrate gas permeable, liquid permeable membranes. A variety of benefits accrue, including more optimal culture conditions during scale up and more efficient use of inventory space, incubator space, and disposal space. Furthermore, labor and contamination risk are reduced.
US08809036B2 Secretion expression of antibiotic peptide CAD in Bacillus subtilis and expression system of recombination Bacillus subtilis
The present invention relates to a method for expressing antimicrobial peptide CAD by means of a recombinant Bacillus subtilis expression system. The SUMO protease expression operon is first artificially synthesized. The protein expression operon genes of Saccharomyces cerevisiae small ubiquitin-related protein is then fused with the antibacterial peptide AD. The fusion protein is further cloned into the pNF11 plamid to be introduced into Bacillus subtilis, thereby ensuring the induced expression of recombined Bacillus subtilis in shake flasks. The method has the advantages of a simple expression system, large-scale production, low production cost, strong biological activity and no toxic or harmful substance production. Moreover, the method provides a medicine with low price and strong antibacterial capacity for clinic disease prevention and treatment. This invention can also be used as a feedstuff additive.
US08809035B2 Canine probiotic Bifidobacterium
According to the invention there is provided a strain of lactic acid bacteria of the species Bifidobacterium globosum obtainable by isolation from resected and washed canine gastrointestinal tract having a probiotic activity in animals. Methods of use and compositions comprising the Bifidobacterium globosum of the present invention are also provided.
US08809026B2 Processes for producing lipids
The present invention relates to processes for extracting lipid from vegetative plant parts such as leaves, stems, roots and tubers, and for producing industrial products such as hydrocarbon products from the lipids. Preferred industrial products include alkyl esters which may be blended with petroleum based fuels.
US08809025B2 Algae processing
A method for culturing algae comprising, forming an emulsion comprising a gaseous stream and a media utilizing a high shear device, wherein the emulsion comprises gas bubbles, and wherein the high shear device comprises at least one toothed rotor and at least one stator; introducing the emulsion into a bioreactor; and introducing an algae into the bioreactor for growing the algae culture. Additionally, a method for producing liquids from an algae culture, the method comprising forming an emulsion comprising a buffer and algal components, wherein the emulsion comprises algal component globules; separating algal hydrocarbons; and processing algal hydrocarbons to form liquid hydrocarbons. Additionally, a system for producing liquids from an algae culture comprising at least one high shear device.
US08809024B2 Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor
A process for production of cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV is provided which employs a BOC-protected amine of the structure prepared by subjecting an acid of the structure to reduce amination by treating the acid with ammonium formate, nicotinamide adenine dinucleotide, dithiothreitol and partially purified phenylalanine dehydrogenase/formate dehydrogenase enzyme concentrate (PDH/FDH) and without isolating treating the resulting amine of the structure 2 with di-tert-butyl dicarbonate to form the BOC-protected amine.
US08809022B2 Modified RNA ligase for efficient 3′ modification of RNA
The invention provides a novel truncated mutated T4 RNA ligase 2. In addition, methods are provided for ligating pre-adenlylated donor molecules to the 3′ hydroxyl group of RNA in the absence of ATP using the ligase.
US08809020B2 Method enabling the use of extracellular ribonucleic acid (RNA) extracted from plasma or serum to detect, monitor or evaluate cancer or premalignant conditions
This invention relates to the use of tumor-derived or associated extracellular ribonucleic acid (RNA) found circulating in blood plasma or serum fraction for the detection, monitoring, or evaluation of cancer or premalignant conditions. Specifically, this invention enables the extraction of circulating RNA from plasma or serum and utilizes nucleic acid amplification assays for the identification, detection, inference, monitoring, or evaluation of any neoplasm, benign, premalignant, or malignant, in humans or other animals, which might be associated with that RNA. Further, this invention allows the qualitative or quantitative detection of tumor-derived or associated extracellular RNA circulating in the plasma or serum of humans or animals with or without any prior knowledge of the presence of cancer or premalignant tissue.
US08809018B2 Modified nucleotide molecules of xylanase and application thereof
Modified nucleotide molecules of xylanase and the application of the nucleotide molecules in constructing recombinant vectors, host cells or producing xylanase are disclosed, wherein the nucleotide molecules contain nucleotide sequences having greater than 80% identity with nucleotide sequence shown by SEQ ID NO: 1.
US08809017B2 IRES mediated multicistronic vectors
This invention relates to nucleic acid molecules comprising at least one nucleic acid sequence encoding for a peptide or protein of interest, at least one nucleic acid sequence encoding for a selectable marker, and at least one IRES sequence, wherein the at least one IRES sequence is located between the at least one nucleic acid sequence encoding for the peptide or protein of interest and the at least one nucleic acid sequence encoding for the selectable marker. Furthermore, this invention relates to host cells comprising such nucleic acid molecule and to methods of recombinant protein expression using such host cells.
US08809016B2 Nucleic acids encoding modified vitamin K-dependent polypeptides
The invention provides vitamin K-dependent polypeptides with enhanced membrane binding affinity. These polypeptides can be used to modulate clot formation in mammals. Methods of modulating clot formation in mammals are also described.
US08809014B2 Method for assessing the condition of skin and/or scalp
Method for assessing condition of skin and/or scalp by resulted color from the interaction of protein detecting composition with skin and/or scalp sample. Also disclosed is a method for comparing condition of different skin and/or scalp using the above method. Such conditions include, for example, skin healthiness and dandruff condition of scalp.
US08809013B2 Stable NAD/NADH derivatives
The present invention provides for stable nicotinamide adenine dinucleotide (NAD/NADH) and nicotinamide adenine dinucleotide phosphate (NADP/NADPH) derivatives of formula (I), enzyme complexes of these derivatives and their use in biochemical detection methods and reagent kits.
US08809007B2 Method for determining the activity of a proteolytic coagulation factor in a sample
A method for determining the activity of a proteolytic coagulation factor in a sample may include (a) providing and incubating a reaction mixture comprising (i) the sample, (ii) an agent for direct or indirect activation of the proteolytic coagulation factor in the sample, (iii) a cleavable substrate which has at least one cleavage site for the activated coagulation factor, (iv) a solid phase to which the cleavable substrate is bound or becomes bound during the incubation; (b) separating off the solid phase; and (c) determining the amount of solid-phase-bound, uncleaved substrate, wherein the determined amount of solid-phase-bound, uncleaved substrate indicates a quantitative measure of the activity of the proteolytic coagulation factor in the sample.
US08809006B2 Hemostasis assay
Provided is a hemostasis assay comprising a reaction mixture comprising a blood product to be tested, a trigger molecule for inducing thrombin generation, a thrombin-specific substrate which, upon cleavage by thrombin, produces a measurable thrombin-specific signal, a trigger molecule for inducing plasmin generation, a plasmin-specific substrate which, upon cleavage by plasmin, produces a measurable plasmin-specific signal, a phospholipid-containing surface, and calcium ions. The assay allows determination of the amount of thrombin and the amount of plasmin generated in the reaction mixture in time, starting at t=0, by measuring the thrombin-specific and plasmin-specific signals.
US08809002B2 MUC1, caspase-8, and DED-containing proteins
The disclosure features a variety of compositions and methods for modulating an interaction between MUC1 and caspase-8 and/or an interaction between MUC1 and a DED-containing protein (e.g., an anti-apoptotic DED-containing protein or a pro-apoptotic DED-containing protein). Such methods and compositions are useful for the treatment or prevention of e.g., a variety of pathological disorders characterized by elevated or decreased levels of apoptosis. Moreover, the compositions and methods are also useful to identify, design, and generate compounds that modulate the interactions. The compounds and/or pharmaceutical compositions containing the compounds can be used in the treatment of disease.
US08809000B2 Methods of screening heteromeric T1R2/T1R3 receptors for compounds which modulate sweet taste signaling
Newly identified mammalian taste-cell-specific G protein-coupled receptors which function as hetero-oligomeric complexes in the sweet taste transduction pathway, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in sweet taste signaling as hetero-oligomeric complexes, and the genes and cDNA encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for identifying putative taste modulating compounds using such hetero-oligomeric complexes also described, as is a novel surface expression facilitating peptide useful for targeting integral plasma membrane proteins to the surface of a cell.
US08808998B2 Diagnostic method for atherosclerosis
The invention relates to a method of identifying/monitoring active atherosclerotic plaques associated with blood vessel walls wherein the plaques comprise activated macrophages having accessible binding sites for a ligand. The method comprises the steps of administering to a patient being evaluated for atherosclerosis an effective amount of a composition comprising a conjugate of a ligand and a chromophore capable of emitting light under predetermined conditions, allowing sufficient time for the ligand conjugate to bind to the activated macrophages, subjecting the blood vessels to the predetermined conditions using a catheter-based device, and identifying active plaques by detecting light emitted by the chromophore using a catheter-based device or by using an external imaging technique. The invention also relates to a similar method wherein a chemical moiety capable of emitting radiation is conjugated to the ligand.
US08808995B2 Methods for genotyping selected polymorphism
Methods for genotyping polymorphisms using a locus specific primer that is complementary to a region near a selected polymorphism are described. Methods for synthesizing pools of locus specific primers that incorporate some degenerate positions are also disclosed. A plurality of different sequence capture probes are synthesized simultaneously using degenerate oligonucleotide synthesis. The sequence of the locus specific regions of the capture probes are related in that they have some bases that are identical in each sequence in the plurality of sequences and positions that vary from one locus specific region to another. The sequences are selected based on proximity to a polymorphism of interest and because they conform to a similar sequence pattern.
US08808994B2 Genes involved in estrogen metabolism
The invention concerns genes that have been identified as being involved in estrogen metabolism, and are useful as diagnostic, prognostic and/or predictive markers in cancer. In particular, the invention concerns genes the tumor expression levels of which are useful in the diagnosis of cancers associated with estrogen metabolism, and/or in the prognosis of clinical outcome and/or prediction of drug response of such cancers.
US08808993B2 Methods and kits to detect new H1N1 “swine flu” variants
Methods and kits used in the detection of the H1N1/09 influenza virus are provided. The methods include the use of nucleic acids to detect H1N1/09 generally as well as H1N1/09 variants resistant to antiviral compositions.
US08808992B2 SHOC2 mutations causing noonan-like syndrome with loose anagen hair
The present invention is directed to methods of diagnosing Noonan-like syndrome with loose anagen hair comprising detecting a mutation in SHOC2 gene. One specific diagnostic mutation disclosed is an A-to-G transition at position 4 resulting in a mutation at position 2 of SHOC2 amino acid sequence from serine to glycine. The invention also provides related sequences and kits.
US08808987B2 Method for identifying olfactory receptor included in one olfactory cell
The present invention provides a novel method for identifying an olfactory receptor included in one olfactory cell. In the present invention, amplified is the cDNA derived from the mRNA of the one olfactory cell by a PCR method using a forward primer represented by SEQ ID: 01 and a reverse primer represented by SEQ ID: 02. Subsequently, determined is whether or not a gene sequence of the amplified cDNA is identical to one gene sequence included in gene sequences coding for olfactory receptors included in the mouse olfactory receptor group A. Finally, determined is that, if the gene sequence of the cDNA is identical to the one gene sequence in the previous step, the olfactory receptor included in the one olfactory cell is the olfactory receptor corresponding to the one gene sequence which is identical to the gene sequence of the cDNA in the previous step.
US08808986B2 Methods and devices for high fidelity polynucleotide synthesis
Disclosed are methods for synthesizing and/or assembling at least one polynucleotide product having a predefined sequence from a plurality of different oligonucleotides. In exemplary embodiments, the methods involve synthesis and/or amplification of different oligonucleotides immobilized on a solid support, release of synthesized/amplified oligonucleotides in solution to form droplets, recognition and removal of error-containing oligonucleotides, moving or combining two droplets to allow hybridization and/or ligation between two different oligonucleotides, and further chain extension reaction following hybridization and/or ligation to hierarchically generate desired length of polynucleotide products.
US08808982B2 Compositions and methods for reprogramming eukaryotic cells
The present invention relates to methods for changing the state of differentiation of a eukaryotic cell, the methods comprising introducing mRNA encoding one or more reprogramming factors into a cell and maintaining the cell under conditions wherein the cell is viable and the mRNA that is introduced into the cell is expressed in sufficient amount and for sufficient time to generate a cell that exhibits a changed state of differentiation compared to the cell into which the mRNA was introduced, and compositions therefor. For example, the present invention provides mRNA molecules and methods for their use to reprogram human somatic cells into pluripotent stem cells.
US08808979B2 Methods related to liver enzyme induction as a predisposition for liver toxicity and diseases or disorders associated therewith
The present invention pertains to the field of toxicological assessments for risk stratification of chemical compounds. Specifically, it relates to a method for diagnosing the pro-pathological effect of compounds which are inducing liver enzymes. It also relates to a method of determining whether a compound is capable of exhibiting pro-pathological effects on the liver by enzyme induction in a subject and to a method of identifying a drug for treating the pro-pathological effect of liver enzyme induction. Furthermore, the present invention relates to a data collection comprising characteristic values of at least five analytes, a data storage medium comprising said data collection, and a system and a device for diagnosing the pro-pathological effect of liver enzyme induction. Finally, the present invention pertains to the use of a group of analytes or means for the determination thereof for the manufacture of a diagnostic device or composition for diagnosing the pro-pathological effect of liver enzyme induction in a subject. For each sex, a different metabolome pattern, i.e. a different set of analytes is disclosed. The liver enzyme induction markers are mainly selected from free fatty acids, but also include various phosphatidylcholines, galactose, 3- and 5-Methoxysphingosine, Cholesterol, Threonic acid, 1,2-Dioleoyl-sn-glycero-3-phosphatidyl-L-serine, Glycerol, Glycerophosphate, Dodecanol, myo-Inositol-2-monophosphate.
US08808975B2 Positive resist composition for immersion exposure and pattern-forming method using the same
A positive resist composition for immersion exposure comprises: (A) a resin capable of increasing its solubility in an alkali developer by an action of an acid, and (B) a compound capable of generating an acid upon irradiation with actinic ray or radiation, wherein the acid satisfies conditions of V≧230 and V/S≦0.93 taking van der Waals volume of the acid as V (Å3), and van der Waals surface area of the acid as S (Å2).
US08808973B2 Method of forming pattern
According to one embodiment, there is provided a method of forming a pattern including forming a polymer layer on a substrate, the polymer layer including a first and second regions, selectively irradiating either of the first and second regions with energy rays or irradiating the first and second regions with energy rays under different conditions to cause a difference in surface free energy between the first and second regions, thereafter, forming a block copolymer layer on the polymer layer, and causing microphase separation in the block copolymer layer to simultaneously form first and second microphase-separated structures on the first and second regions, respectively.
US08808971B2 Method for forming fine patterns of semiconductor device
A method for forming fine patterns of a semiconductor device employs a double patterning characteristic using a mask for forming a first pattern including a line pattern and a mask for separating the line pattern, and a reflow characteristic of a photoresist pattern.
US08808969B2 Method of making radiation-sensitive sol-gel materials
Radiation-sensitive sol-gel compositions are provided, along with methods of forming microelectronic structures and the structures thus formed. The compositions comprise a sol-gel compound and a base generator dispersed or dissolved in a solvent system. The sol-gel compound comprises recurring monomeric units comprising silicon with crosslinkable moieties bonded to the silicon. Upon exposure to radiation, the base generator generates a strong base, which crosslinks the sol-gel compound in the compositions to yield a crosslinked layer that is insoluble in developers or solvents. The unexposed portions of the layer can be removed to yield a patterned sol-gel layer. The invention can be used to form patterns from sol-gel materials comprising features having feature sizes of less than about 1 μm.
US08808967B2 Compositions and processes for photolithography
Topcoat layer compositions are provided that are applied above a photoresist composition. The compositions find particular applicability to immersion lithography processing.
US08808964B2 Nitrogen-containing organic compound, chemically amplified positive resist composition, and patterning process
An aralkylcarbamate of imidazole base is effective as the quencher. In a chemically amplified positive resist composition comprising the carbamate, deprotection reaction of carbamate takes place by reacting with the acid generated upon exposure to high-energy radiation, whereby the composition changes its basicity before and after exposure, resulting in a pattern profile with advantages including high resolution, rectangular shape, and minimized dark-bright difference.
US08808959B2 Resist composition, method of forming resist pattern, novel compound, and acid generator
A resist composition including a base component (A) which exhibits changed solubility in an alkali developing solution under action of acid and an acid-generator component (B) including a compound represented by (b1-1), a compound represented by (b1-1′) and/or a compound represented by (b1-1″) (R1″-R3″ represents an aryl group or an alkyl group, provided that at least one of R1″-R3″ represents a substituted aryl group being substituted with a group represented by (b1-1-0), and two of R1″-R3″ may be mutually bonded to form a ring with the sulfur atom; X represents a C3-C30 hydrocarbon group; Q1 represents a carbonyl group-containing divalent linking group; X10 represents a C1-C30 hydrocarbon group; Q3 represents a single bond or a divalent linking group; Y10 represents —C(═O)— or —SO2—; Y11 represents a C1-C10 alkyl group or a fluorinated alkyl group: Q2 represents a single bond or an alkylene group; and W represents a C2-C10 alkylene group).
US08808957B2 Carrier for developing electrostatic image, developer for electrostatic image, developing device, cartridge, process cartridge, image forming method, and image forming apparatus
A carrier for developing an electrostatic image, includes: magnetic core material particles and a coated layer coated on the magnetic core material particles, the coated layer containing a resin having a monomer unit represented by formula (A): wherein R1 represents a hydrogen atom or a methyl group; R2 to R4 each independently represent a hydrogen atom, an alkyl group, an aryl group or an aralkyl group; R5 independently represents an alkyl group, an aryl group or an aralkyl group; n represents an integer of from 0 to 7; and L1 represents a single bond or an alkylene group, provided that at least one of R3 and R4 is not a hydrogen atom.
US08808952B2 Composition for forming charge transporting film, electrophotographic photoreceptor, process cartridge, and image forming apparatus
Provided is a composition for forming a charge transporting film, including a solvent having a dielectric constant of 5.0 or more, at least one kind of compound selected from a group consisting of the following compounds (I-a), (I-b), (I-c), and (I-d) and a compound represented by the following Formula (II), fluorine-containing resin particles, and a fluorine-containing dispersant, (I-a): a compound represented by the following Formula (III) (I-b): a compound represented by the following Formula (V) (I-c): a compound represented by the following Formula (V) (I-d): a compound represented by the following Formula (V)
US08808949B2 Dye dispersion liquid, photosensitive resin composition for color filters, color filter, liquid crystal display device and organic light emitting display device
A photosensitive resin composition comprising a dye (A), a dispersant (B), a solvent (C), and a photosensitive binder component (D), the dye (A) being dispersed in the solvent (C) by the dispersant (B), wherein the dye (A) is a dye having a sulfonic acid group; the dispersant (B) is a block polymer that contains a block portion comprising a repeating unit having a tertiary amine; the solvent (C) is a solvent having a solubility of the dye (A) of 0.2 (g/100 g solvent) or less at 23° C.; and a micelle is formed by an acid-base interaction between the tertiary amine of the dispersant (B) and the sulfonic acid group of the dye (A).
US08808948B2 Dispersion composition, photosensitive resin composition for light-shielding color filter, light-shielding color filter, method of producing the same, and solid-state image sensor having the color filter
A method of producing a dispersion composition containing titanium black, a solvent and a dispersant including at least a first dispersant and a second dispersant, and the method includes dispersing a mixed liquid containing the titanium black, the first dispersant and the solvent, and adding the second dispersant to the dispersed mixed liquid and dispersing the same, wherein at least a part of the dispersant has an acid value of 50 mgKOH/g or more.
US08808946B2 Urethane acrylate having a high refractive index and reduced double bond density
The invention relates to novel specially substituted urethane acrylates based on tris(p-isocyanatophenyl)thiophosphate having a high refractive index and reduced double bond density, and to a method for the production and use thereof.
US08808945B2 Fabrication process for cholesteric liquid crystal media having a volume hologram
A volume hologram layer (2) is formed on a substrate (1), and a cholesteric liquid crystal layer (3) is then formed on the hologram layer (2). After the substrate (1) is peeled off the volume hologram layer (2), an adhesive layer (4) is formed on the surface of the volume hologram layer (2) with the substrate (1) peeled off, and another substrate (5) is then formed on the adhesive layer (4). Finally, a label form of cholesteric liquid crystal medium having a volume hologram is shaped out of the resulting multilayer structure; it is thus possible to fabricate cholesteric liquid crystal media having a volume hologram with efficiency yet without recourse to any complicated steps such as an alignment step.
US08808943B2 Membrane electrode assembly including porous catalyst layer and method of manufacturing the same
A membrane electrode assembly for a fuel cell including a porous catalyst layer, and a method of manufacturing the same in which an electrode includes a catalyst layer formed adjacent to a surface of an electrolyte membrane, and the catalyst layer has a uniform porosity as pluralities of pores are uniformly distributed on the catalyst layer.
US08808942B2 Adhesive for fuel cell and membrane-electrode assembly produced using the same
An adhesive suitable for solid polymer fuel cells is provided that has sufficient bond durability, so that the solid polymer electrolyte membrane and the gas diffusion layer do not separate, even with the solid polymer electrolyte fuel cell repeatedly wetting and drying, and changing in dimension. An adhesive including a base compound, a cross-linking agent, an adhesion promoting agent, and a reaction catalyst is employed using a specific base compound having alkenyl groups, and a specific cross-linking agent having Si—H groups, in which the ratio of moles of the above Si—H group relative to moles of the above alkenyl group (moles of Si—H group/moles of alkenyl group) is adjusted to the range of 1.0 to 5.0.
US08808940B2 Solid oxide fuel cell with sealed structure
This invention relates to the presence of slightly or non-porous zones in the electrode layer around gas inlets, in order to improve the leak tightness between the different individual cells making up a fuel cell with a plane geometry. The fuel cell comprises a first electrode layer having a non-porous zone forming a passage therethrough for gas flow and an electrolyte layer having a protuberance which extends into the first electrode layer for forming the non-porous zone with the non-porous zone representing a gas tight passage. Nested contact between the bipolar plate and the ceramic triple layer making up the basic cell is also described and is another possible means of avoiding mixes of gasses.
US08808935B2 Fuel cell system
A fuel cell system including a fuel cell, a reformer, a combustor that heats the reformer using anode off-gas of the fuel cell as a fuel, and a ratio controller that controls a ratio of a combustion component supplied to the combustor in accordance with a temperature distribution in a gas flow direction inside the combustor.
US08808933B2 Semiconductor wire array structures, and solar cells and photodetectors based on such structures
A structure comprising an array of semiconductor structures, an infill material between the semiconductor materials, and one or more light-trapping elements is described. Photoconverters and photoelectrochemical devices based on such structure also described.
US08808931B2 Ion exchange filter for fuel cell system
The present invention is directed toward ion exchange filters useful in fuel cell systems, fuel cell systems including ion exchange filters and methods for treating fluid of fuel cells. One embodiment of the invention includes a cartridge containing an anion exchange resin in bicarbonate form. The invention is particularly useful in connection with vehicle mounted fuel cell systems.
US08808926B2 Electrode active material for all-solid-state secondary battery and all-solid-state secondary battery using the same
An all-solid-state secondary battery that includes a positive electrode, a negative electrode, and a solid electrolyte, and which has good moldability and favorable battery characteristics. In the all-solid-state secondary battery, a carbon material having carbon particles with a fracture strength of 100 MPa or less is used for an electrode active material.
US08808925B2 Microporous polymer membrane modified by aqueous polymer, manufacturing method and use thereof
Microporous polyolefin membrane modified by aqueous polymer of the invention is obtained by the following steps: copolymerizing 100 parts of a water-soluble polymer, 30-500 parts of a hydrophobic monomer, 0-200 parts of a hydrophilic monomer and 1-5 parts of an initiator into polymeric colloid emulsion; adding 0-100% of an inorganic filler and 20-100% of a plasticizer based on 100% solid content of the polymeric colloid emulsion to obtain slurry; and coating the slurry on one or two surfaces of the surface modified microporous polyolefin membrane and then drying. The microporous polyolefin membrane modified by aqueous polymer has thermal shutdown effect and little thermal shrinkage, and improves the main problem of shrinkage of the microporous polyolefin membrane at high temperature.
US08808923B2 Separator for non-aqueous electrolyte secondary battery and non-aqueous electrolyte secondary battery using the same
Disclosed is a separator for a non-aqueous electrolyte secondary battery, the separator including a biaxially-oriented polyolefin porous film including extended-chain crystals and folded-chain crystals, wherein the extended-chain crystals and the folded-chain crystals form a shish-kebab structure. The average distance between the extended-chain crystals adjacent to each other is 1.5 μm or more and less than 11 μm, and the average distance between the folded-chain crystals adjacent to each other is 0.3 μm or more and less than 0.9 μm. A heat resistant porous film may be laminated on the polyolefin porous film. The heat resistant porous film includes a resin having heat resistance or a melting point higher than a melting point of the polyolefin porous film.
US08808922B2 Electrode assembly and secondary battery using the same
An electrode assembly and a secondary battery using the same. In an embodiment, the electrode assembly includes one or more first electrodes each having a first tab provided to one surface thereof, and one or more second electrodes each having a second tab provided to one surface thereof. The second electrodes are alternately stacked with the first electrodes. A separator is interposed between the first and second electrodes and folded a plurality of times so that the same surfaces of the separator face each other. The separator has one or more tab through-holes through which the first and second tabs protrude at folded portions of the separator.
US08808921B2 Current collector for flexible electrode, method of manufacturing same, and negative electrode including same
Disclosed are a current collector for a flexible electrode, a method of manufacturing the same, and a negative electrode including the same. The current collector for a flexible electrode includes: a flexible polymer substrate; a cross-linkable polymer layer disposed on the polymer substrate; and a metal layer disposed on the cross-linkable polymer layer, wherein the surface of the cross-linkable polymer layer includes a plurality of protrusions and grooves.
US08808920B2 Positive electrode active material, positive electrode, nonaqueous electrolyte cell, and method of preparing positive electrode active material
Disclosed herein is a positive electrode active material prepared by mixing a lithium-containing compound, a compound containing a transition metal to be put into a solid solution, and a compound containing a metallic element M2 different from the transition metal, and firing the mixture to form composite oxide particles, depositing a compound containing at least one element selected from among sulfur (S), phosphorus (P) and fluorine (F) on surfaces of the particles, and firing the particles, whereby each of the particles is provided with a concentration gradient such that the concentration of the metallic element M2 increases from the center toward the surface of the particle, and at least one element selected from among (S), (P) and (F) is made present in the form of being aggregated at the surfaces of the composite oxide particles.
US08808914B2 Lead-acid battery design having versatile form factor
An electrochemical storage device comprises a plurality of layer electrodes, wherein each layer electrode includes a first charged sector and a second charged sector, wherein the second charged sector is charged oppositely compared to the first charged sector, and wherein the plurality of layer electrodes are assembled with respect to each other such that the first charged sector of a first plate of the plurality of layer electrodes is laid below the second charged sector of a second plate of the plurality of layer electrodes located immediately above the first plate, wherein the charges of the first charged sectors of the first and second plates have a first sign and the charges of the second charged sectors of the first and second plates have a second sign that is opposite the first sign; a separator sector located, and enabling ionic charge exchange between the first charged sector of the first plate and the second charged sector of the second plate.
US08808913B2 Composite positive electrode active material, electrode for lithium secondary battery including composite positive electrode active material, and lithium secondary battery
Provided are a composite positive electrode active material, an electrode for a lithium secondary battery including the composite positive electrode active material, and a lithium secondary battery, and more particularly, a composite positive electrode active material including lithium composite oxide, activated carbon, and carbon black, an electrode for a lithium secondary battery including the composite positive electrode active material, and a lithium secondary battery. The present disclosure may provide a lithium secondary battery having improved rate characteristics in a low-temperature atmosphere.
US08808912B2 Surface protected lithium-metal-oxide electrodes
A lithium-metal-oxide positive electrode having a layered or spinel structure for a non-aqueous lithium electrochemical cell and battery is disclosed comprising electrode particles that are protected at the surface from undesirable effects, such as electrolyte oxidation, oxygen loss or dissolution by one or more lithium-metal-polyanionic compounds, such as a lithium-metal-phosphate or a lithium-metal-silicate material that can act as a solid electrolyte at or above the operating potential of the lithium-metal-oxide electrode. The surface protection significantly enhances the surface stability, rate capability and cycling stability of the lithium-metal-oxide electrodes, particularly when charged to high potentials.
US08808905B2 Cylinder type lithium ion secondary battery
A cylinder type lithium ion secondary battery has a center pin that is inserted into an electrode assembly after the injection of electrolyte to increase impregnation of the electrolyte. The battery includes an electrode assembly, a case to accommodate the electrode assembly, a center pin inserted into the center of the electrode assembly, a cap assembly to seal an upper end opening of the electrode assembly, and an upper insulating plate disposed between the electrode assembly and the cap assembly. The upper insulating plate has a hollow formed in the center through which the center pin can penetrate, and the hollow has a center pin separation preventing unit bendable only toward the electrode assembly when the center pin penetrates through the hollow.
US08808904B2 Secondary battery with protective circuit module and secondary protective element assembly
A secondary battery with a protective circuit module including a rechargeable bare cell having a first electrode and a second electrode and a protective circuit module having a protective circuit for the rechargeable bare cell. A conductive bonding layer is located on the protective circuit module and a secondary protective element assembly is attached to the protective circuit module by the conductive bonding layer. A first lead plate electrically connects the secondary protective element assembly to the first electrode, and a second lead plate electrically connects the protective circuit module to the second electrode.
US08808903B2 Battery with wound electrode group and positive and negative electrode insulating covers
According to one embodiment, there is provided a battery. The battery includes a metallic outer can, a wound electrode group, a positive electrode-lead, a negative electrode-lead, a positive electrode insulating cover, and a negative electrode insulating cover.
US08808898B2 Battery pack for an electric powertrain vehicle
A battery pack includes at least a first stack of battery modules, and a second stack of battery modules, each stack including a plurality of battery modules arranged in parallel in side by side relationship extending in a longitudinal direction, the battery pack further including at least one heat exchanger interposed between the first and second stacks, the heat exchanger being in thermal contact with interstack coupling surfaces extending in a longitudinal and transversal plan [L-T] of the battery modules. The invention also relates to a corresponding heat exchanger.
US08808896B2 Battery pack of excellent structural stability
Disclosed is a battery pack including a battery module array having battery modules which are arranged in a lateral direction in two or more rows, each of the battery modules configured with battery cells or unit modules, each of which has two or more battery cells mounted therein, are stacked in a state in which the battery cells or the unit modules are erected vertically, a base plate on which the battery modules are stacked in a vertically erected state, a pair of main members provided at the front and rear of the battery module array, opposite ends of each of the main members being fastened to an external device, a pair of end plates disposed in contact with the front and rear of the battery module array such that the lower end of each of the end plates is fixed to the base plate, and supporting bars.
US08808892B2 Temporary insulator for battery packs and associated systems and methods
Battery packs having electrically insulating material between conductive surfaces of electrical components are described herein. In some embodiments, a battery pack includes a battery cell with a first conductive surface, an electrically conductive member with a second conductive surface, and electrically insulating material positioned between the first and second conductive surfaces. The electrically insulating material has at least one passage that enables the first and second conductive surfaces to be electrically connected. For example, the passage in the electrically insulating material may be formed by, during, or as a result of a process in which the first and second conductive surfaces are attached, such as by a welding process that both ablates a portion of the electrically insulating material to form the through passage and that physically joins the first and second conductive surfaces, thereby creating an electrical connection therebetween.
US08808890B2 Battery system and battery safety alarm system
A battery system that can prevent a burst of a battery and a battery safety alarm system therefor are provided. A battery system includes a lithium ion battery formed in a cylindrical shape and including an organic electrolytic solution as an electrolyte. A laser beam source emits a laser beam. An optical fiber of a single mode is wound around an outer circumferential portion of the lithium ion battery in a plurality of lines and via which the laser beam emitted from the light source is transmitted. A detector receives the laser beam transmitted via the optical fiber and detects abnormality of the lithium ion battery on the basis of a loss of the laser beam due to the optical fiber or a change with time of the loss. An alarm warns a user of the abnormality when abnormality of the lithium ion battery is detected by the detector.
US08808888B2 Flow battery systems
Embodiments of the invention generally provide for flow battery cells and systems containing a plurality of flow battery cells, and methods for improving metal plating within the flow battery cell, such as by flowing and exposing the catholyte to various types of cathodes. In one embodiment, a flow battery cell is provided which includes a cathodic half cell and an anodic half cell separated by an electrolyte membrane, wherein the cathodic half cell contains a plurality of cathodic wires extending perpendicular or substantially perpendicular to and within the catholyte pathway and in contact with the catholyte, and each of the cathodic wires extends parallel or substantially parallel to each other. In some examples, the plurality of cathodic wires may have at least two arrays of cathodic wires, each array contains at least one row of cathodic wires, and each row extends along the catholyte pathway.
US08808887B2 Battery pack
A battery module includes a plurality of battery cells aligned in one direction, each battery cell having electrode terminals, a bus bar coupling the electrode terminals, a terminal shielding unit covering the bus bar, the terminal shielding unit including an upper shielding unit and a lower shielding unit with at least one opening, a pair of first and second end plates arranged outside outermost battery cells, and at least one coupling member coupling the first and second end plates.
US08808882B2 Coated article having boron doped zinc oxide based seed layer with enhanced durability under functional layer and method of making the same
A coated article is provided with at least one functional layer, such as an infrared (IR) reflecting layer(s) of or including silver and/or gold. A dielectric and substantially transparent seed layer is provided under and directly contacting the functional layer. In certain example embodiments, the seed layer includes an oxide of zinc and boron for increasing the hardness of the layer and thus improving durability of the overall coating. The seed layer may further include aluminum and/or gallium, for enhancing the electrical properties and/or reducing the stress in the resulting coating. The seed layer may be deposited by a substantially metallic target in the presence of oxygen in certain examples.
US08808872B2 Germanium-containing solder, a component comprising a solder and a process for soldering
A germanium containing nickel-based solder having a similar composition to a nickel-based superalloy is provided. As a result of which the proportion of γ′ formed in the solder is reduced. The solder also includes chromium, cobalt, molybdenum, tungsten, aluminum, and titanium. A component including the solder is also provided.
US08808871B2 Rotation tool
A sintered cermet of a rotary tool has a hard phase with a first hard phase and a second hard phase comprising a carbide, a nitride, and a carbonitride of at least one of group 4, 5, and 6 metals of the periodic table of which metals the metal titanium is a main component. The result of an X-ray diffraction measurement in a surface region of the sintered cermet provides a first peak intensity Ib on a high angle side that is attributable to a (220) plane of the first hard phase and a second peak intensity Ia on a low-angle side that is attributable to a (220) plane of the second hard phase, and an intensity ratio Ib/Ia of the first peak intensity Ib to the second peak intensity Ia is in the range of 0.5 to 1.5.
US08808869B2 Treatment agent for use in lignocellulose material
An objective of the present invention is to provide a lignocellulose material exhibiting superior dimensional stability and having a reduced water-absorbing property, as well as provide a lignocellulose hybrid material, a paper product or a wood product, with superior dimensional stability and a reduced water-absorbing property. In the present invention, a lignocellulose material is treated with a treatment agent for use in a lignocellulose material containing: (A) a polyvalent carboxylic acid or a derivative thereof; and (B) a silicon compound containing a functional group binding to a silicon atom, and thereby, a lignocellulose hybrid material is obtained. In addition, a paper product or a wood product is obtained by using the aforementioned lignocellulose hybrid material.
US08808864B2 Coated article with IR reflecting layer and method of making same
An IG window unit includes a coating supported by a glass substrate. The coating includes at least the following on the glass substrate moving from the glass substrate outwardly: at least one dielectric layer; a layer comprising zinc oxide; an infrared (IR) reflecting layer comprising silver; a layer comprising an oxide of Ni and/or Cr; an overcoat comprising a layer comprising tin oxide located over the oxide of Ni and/or Cr and a layer comprising silicon nitride.
US08808862B2 Resin composition for insulation film
A resin composition includes (A) 100 parts by weight of epoxy resin; (B) 20 to 100 parts by weight of polybutadiene styrene divinylbenzene graft terpolymer resin; (C) 2 to 20 parts by weight of di-tert-butylhydroquinone (DTBHQ); (D) 5 to 50 parts by weight of polyphenyl ether modified cyanate ester resin; and at least one of (E) inorganic filler, (F) chain extending sealing agent, and (G) catalyst. The resin composition is characterized by specific ingredients and proportions thereof to attain high heat resistance, low dielectric constant Dk, and low dielectric dissipation factor Df, and being halogen-free, and therefore is applicable to protective film of printed circuit boards, insulating protective film of electronic components, and resin insulation film of leadframes.
US08808857B1 Carbon nanotube array interface material and methods
An interface material employing carbon nanotube (CNT) array and a method of fabricating the same. A first CNT array is provided on a first substrate. A second CNT array is provided on a second substrate. A first support layer is disposed on the first CNT array, wherein the first CNT array is between the first support layer and the first substrate. A second support layer is disposed on the second CNT array, wherein the second CNT array is between the second support layer and the second substrate. The first support layer is attached to the second support layer. The first and second substrates are removed, thereby providing the interface material.
US08808854B2 Matte biaxially oriented polylactic acid film
A biaxially oriented laminate film including a core layer including a blend of crystalline polylactic acid polymer and a minority amount of polyolefin with a compatibilizing resin which is biaxially oriented such that a matte or opaque appearance is obtained. The laminate film may further have additional layers such as a heat sealable layer disposed on one side of the core layer including an amorphous polylactic acid resin and/or a polylactic acid resin-containing layer disposed on the side of the core layer opposite the heat sealable layer, a metal layer, or combinations thereof.
US08808853B2 Coated article and method for making same
A coated article includes a substrate, a color layer formed on the substrate and a ceramic layer deposited on the color layer. The color layer substantially includes metal Zn and O. The ceramic layer substantially includes substance M, O, and N, wherein M is Al or Si.
US08808850B2 Water resistant intumescent fire retardant coating
A fire retardant intumescent coating composition is disclosed, which includes expandable graphite, an aromatic polyamine resin, and a phosphorous-containing compound. An overlay for applying to a wood substrate is also disclosed, which includes a core layer comprising a substrate and a resin composition, a top layer on one side of the core layer comprising the fire retardant intumescent coating composition, and an optional bottom layer on the opposite side of the core layer from the top layer. A process of forming the overlay is also disclosed, which includes applying the resin composition to the core layer substrate to form a resinated core layer, and applying a coating composition on the resinated core layer, directly or indirectly, to form the top layer; wherein the coating composition comprises expandable graphite, an aromatic polyamine resin, and a phosphorous-containing compound.
US08808845B2 Cleansing polyester fabrics, and a process of preparing the same
The cleansing polyester fabric of the present invention (AAA). The cleansing fabric of the present invention is useful as a makeup cleansing fabric or as a wiping fabric for precision products and optical devices since it exhibits excellent cleansing performance, is soft to the touch and does not damage the surface of a products to be cleansed.
US08808842B2 Offset-printable coated white paper having a high fluorescent intensity and method for producing same
The invention concerns a coated white sheet having a fluorescence intensity of more than 55, measured in accordance with international standard ISO 11475: 2004, by the difference between the value for the CIE whiteness under D65 illuminant and the value for this same CIE whiteness after interposing a filter that eliminates wavelengths shorter than 420 nm, and being offset-printable with no mottling, said coated sheet comprising at least one base sheet and a printable white surface coat having a pigmented composition which comprises: —at least some white coating pigments and at least one coating binder; —at least one fluorescent whitening agent in a total quantity of 1% dry weight or more with respect to the dry weight of said pigments; —at least one support substance for said whitening agent in a total quantity of dry weight of more than 2% with respect to the dry weight of said pigments. The invention also concerns a method for producing said coated sheet by curtain coating said pigmented composition.
US08808831B2 Sandwich-type, structural, composite component including at least one hingedly-connected portion, cargo management system and automotive vehicle load floor utilizing the component
A sandwich-type, structural, composite component including at least one hingedly connected portion which pivots with reduced or eliminated hinge binding and a cargo management system and vehicle load floor utilizing the component are provided. Elongated first and second interior portions of the component are locally crushed by the press molding to form a living hinge having a pivot axis and an elongated depression, respectively. The component includes an elongated cut-out which extends completely through the component at the elongated depression to obtain a clearance between a first portion of the component hingedly connected to a second portion of the component by the living hinge. The living hinge and the clearance allow pivotal movement of the first portion between different use positions relative to the second portion with reduced or eliminated hinge binding during the pivotal movement about the pivot axis.
US08808825B2 Rotating device
The present invention comprises a rotating device which comprises two pairs of disks. Each pair has a first disk in a first plane and a second disk in a second plane rigidly joined to the first disk. The second plane is perpendicular to the first plane and the first disk in each pair are detachably attached to one another and the second disk in each pair are detachably attached to one another so that each pair connectedly rotates with respect to each other. Their respective circumferential edges are in contact with one another.
US08808823B2 Device and method for repairing structural components
A device and method to repair a structural component. The device includes a plug that bonds to the structural component. The plug includes a flange and a solid shank extending from the flange, the solid shank being disposable in an opening of the structural component. The device further includes disc that bonds to the structural component such that, when bonded, the disc covers the solid shank of the plug. The method includes bonding the plug to the structural component such that the solid shank of the plug is disposed in the opening of the structural component. The method further includes bonding the disc to the structural component.
US08808822B2 Joint structure for fiber reinforced resin and metal, and joining method for fiber reinforced resin and metal
There is provided a joint structure for a fiber reinforced resin and a metal. In the structure, multiple single elements are laminated such that the step-shaped structures are superposed in a thickness direction. Each element is constituted by a metallic material including a step-shaped structure having an end portion that gradually becomes thinner towards an end surface thereof so as to form a step-shaped joint surface, and a fiber reinforced plastic laminated such that an end portion thereof covers the step-shaped structure smoothly. A main welding portion is formed on an outer end of the metallic material by welding mating surfaces of adjacent metallic materials. A secondary welding portion is formed on the plastic side of the main welding portion on all the metallic materials by welding them in the thickness direction.
US08808818B2 Molded foam
The present invention is a molded foam (foam duct (1)) having a tubular section (100a) with an open end (120a). A parting line (PL), which is formed during molding, extends to the open end (120a). The molded foam includes a protruding portion protruding from the parting line (PL) on one side of the parting line (PL) at least in the proximity of the open end (120a).
US08808816B2 Coating liquid, gas-barrier multilayer structure and gas-barrier shaped article therefrom, and process for producing gas-barrier multilayer structure
Gas-barrier multilayer structures and gas-barrier shaped articles are sufficiently prevented from clouding even when exposed to cold water at 30° C. or below and have excellent gas barrier properties. Processes for producing such gas-barrier multilayer structures, and coating liquids (A) of excellent coating properties that are used to produce the multilayer structures are also provided. A coating liquid (A) includes a solvent mixture of water and an organic solvent and a polycarboxylic acid polymer partially neutralized with a polyvalent metal wherein the polymer is both dissolved and dispersed as particles in the solvent mixture and wherein the particles dispersed account for 5 to 80 wt% of 100 wt% of the polycarboxylic acid polymer partially neutralized with a polyvalent metal.
US08808813B2 Method of producing liquid crystalline coating liquid, and optically anisotropic film
The present invention provides a method of producing a liquid crystalline coating liquid that substantially does not contain a fine crystal. The method of producing a liquid crystalline coating liquid of the present invention contains a heating step of heating a treatment liquid containing a lyotropic liquid crystalline compound containing an impurity, and a solvent, a depositing step of depositing a deposit by cooling the treatment liquid after the heating step to a temperature lower than 40° C., and a removing step of removing the deposit from the treatment liquid.
US08808809B2 Method for applying hot melt adhesive powder onto a shoe or sole part
A method for applying hot melt adhesive powder onto a sole or shoe part includes the steps of applying a cleaning agent, irradiating, applying a conductive liquid which has a conductivity at least 100 times higher than purified water which has a conductivity of 5.5·10−6 S/m, spraying hot melt adhesive powder; and heating. The method can save energy, reduce the working space, reduce the labor intensity and improve the working environment by continuously carrying out the spraying and the melting operation of the hot melt adhesive.
US08808806B2 Inks and coatings that prevent the migration of heavy metals
A composition which cures in ambient conditions to form a film substantially impenetrable to heavy metals, contains water, a water-miscible organic solvent, a water-borne primary resin having a glass transition temperature of 25 degrees C. or less, and a hydrophobic surfactant.
US08808805B2 Coating agent with high scratch resistance and weathering resistance
The present invention relates to a coating composition comprising (d) at least one binder (A) having reactive groups, (e) at least one crosslinking agent (B) which is able to react, with crosslinking with the reactive groups of the binder (A), and at least one catalyst (C) for the crosslinking of silane groups, one or more constituents (A) and/or (B) and/or at least one further constituent of the coating composition containing hydrolyzable silane groups, wherein the catalyst (C) is a phosphoric acid compound, more particularly phosphoric acid or phosphonic acid, which is blocked with an amine having a pKb≧3 and a boiling point >100° C.
US08808804B2 Water-entrained-polyimide chemical compositions for use in high-performance composite fabrication
Water-entrained compositions comprising colloidal or suspensoidal solutions comprising polyimide pre-polymers/oligomers are described. These compositions are obtained in water by initial dispersion of the resin constituents in water to from colloids or suspensoids. The water-entrained polyimide compositions can be applied to numerous surfaces or more beneficially used for composite fabrication. The coated surfaces or polyimide-pre-polymer impregnated reinforcing materials are subsequently cured and are ideal for providing thermal protection.
US08808798B2 Coating method
A coating method includes supplying a coating liquid from a coating nozzle onto a front side central portion of a substrate held on a substrate holding member, rotating the substrate holding member about a vertical axis to spread the coating liquid toward a peripheral portion of the substrate by a centrifugal force and thereby form a film of the coating liquid, forming a liquid film of a process liquid for preventing a contaminant derived from the coating liquid from being deposited or left on a back side peripheral portion of the substrate, and damping a vertical wobble of the peripheral portion of the substrate being rotated, by a posture regulating mechanism, while delivering a gas from delivery holes onto a back side region of the substrate on an inner side of the peripheral portion on which the liquid film is formed.
US08808797B2 Method of manufacturing a gas barrier plastic container
Methods of manufacturing a gas barrier plastic container include a method in which the inside of a vacuum chamber which houses a plastic container is exhausted to form a pre-set pressure, and while maintaining a state where electricity is supplied to a thermal catalyst arranged inside the vacuum chamber to generate heat above a pre-set temperature, a source gas is blown on the thermal catalyst to decompose the source gas and create chemical species, whereby a gas barrier thin film is formed by the chemical species reaching at least one of either the inner surface or the outer surface of the plastic container.
US08808794B2 Method of applying gelcoat and an arrangement performing said method
The present invention relates in general to a method of manufacturing fibre-reinforced parts for a wind power plant, such as a blade, in an open mould. More specifically the invention relates to a process step of applying at least one layer of gelcoat on a interior surface of said open mould prior to arranging at least one layer of material comprising fibre and to an arrangement that can be used in performing said method. The process step comprises to apply the gelcoat from a first end portion of the mould and to a second end portion of the mould and to cover the open mould from said first end portion to said second end portion gradually as gelcoat is applied. The arrangement comprises means for applying gelcoat to the interior surface of the mould (1) and a covering means (6) arranged to gradually cover the open mould (1) as gelcoat is applied.
US08808789B2 Process for forming conductive features
Methods and compositions for preparing highly conductive electronic features are disclosed. When organoamine-stabilized silver nanoparticles are exposed to an alkaline composition, the resulting electronic feature is highly conductive. Such methods are particularly advantageous when applied to aged silver nanoparticle compositions.
US08808788B2 Processing a wafer with a post application bake (PAB) procedure
An Exhaust Gas Analyzer (EGA) subsystem for monitoring exhaust gasses, for controlling and rapidly adjusting the processing conditions within a processing chamber in a thermal processing unit used for heating-treating wafers before and/or during Post Application Bake (PAB) procedures. The EGA subsystem can be used to control and/or optimize the heat-treating of coated wafers at different bake plate temperatures, and the EGA subsystem can provide a high wafer throughput.
US08808784B2 Shortening compositions
Disclosed herein are shortening compositions comprising from about 40% to about 90% sucrose polyester, by weight, wherein said shortening compositions may comprise, based on total weight of the shortening composition, a Solid Fat Index of from about 5% to about 10% solids at 40° C. and a Firmness of from about 90,000 Pa to about 1,500,000 Pa.
US08808780B2 Method and apparatus for making a food chip product
An apparatus (1) for making shaped food chip products (2) including hotplates (3) (4) that are arranged in such way that, when in use, food snacks are hold between the hotplates and where at least one hotplate surface is covered with a steam permeable membrane (5). Also a method for making food chip product (2) including feeding slices of food in a monolayered between hotplates (3, 4) where at least one of the hotplate surfaces pressing on the food snack is covered with a membrane (5) that guidance the steam away.
US08808779B2 Method for reducing the oil content of potato chips
A method is disclosed which reduces the oil content of a potato chip. The method teaches that a steeper, faster temperature drop upon initial introduction of the potato slice to the fryer, followed by a longer period of exposure to lower temperatures before increasing to standard frying temperatures, reduces oil content of a potato chip. The invention further discloses a pre-treatment method which involves submerging the potatoes in a hot water bath which results in decreased oil content. Additionally, the invention discloses a post-treatment method involving subjecting the potato chip to superheated steam that further reduces oil content. The two pre and post-treatment methods, combined with the primary temperature scheme method for reducing oil content, yield a potato chip with significantly reduced oil content.
US08808774B2 pKa buffered flavor enhanced reduced moisture fruits and vegetables
The described pKa process creates a unique combination of active ingredients. The calcium carbonate carrier is impregnated with various proportions of active ingredients and the compounds are made more effective by the sheer and absorption action as they are combined in the described process. The calcium carrier is adjusted to incorporate small amounts of highly efficient/effective pH adjusters. No natural solution exists in Nature with a pH of 10.6 that is optimal for adjusting the pKa naturally in foods. The present invention effects a change in the pKa of most acids and therefore impacts pH which can positively affect flavor, color and taste. The reduced moisture process in combination with the invention solution applied as a treatment results in fruits and vegetables that exhibit cleaner flavors, better texture, enhanced color and lower microbial counts than is found in standard IQF vegetables currently available.
US08808768B2 Development of biochemically standardized extracts from fresh rhizomes of turmeric (Curcuma longa) for treatment of diseases caused by hyperuricemia
The present invention demonstrates the ethanol extracts of fresh rhizome of turmeric (Curcuma longa) strongly inhibit xanthine oxidase, a key biological enzyme responsible for the production of uric acid and superoxide radicals. The dose-response data demonstrate the turmeric extracts prepared with 40% and 50% ethanol are much stronger inhibitors of xanthine oxidase than curcumin. Based on the enzyme-inhibitory data (IC50 values), a biochemical method is developed to standardize turmeric extracts/products as Enzyme-Inhibitory Units (EIU), which has many commercial and biological applications, including, identification and development of pharmacologically effective turmeric products; use of turmeric extracts/products with EIU values >50 per mg to prevent the production of harmful uric acid and superoxides in diseases caused by hyperuricemia and gout; determination of the stability (shelf-life) of turmeric products stored at the retail stores by comparing their EIU values.
US08808767B2 Nematode control agent
A composition for the control of nematodes consisting of salicylaldehyde and a surfactant. Garlic extract added to the salicylaldehyde provides a composition that demonstrates a more potent control action against potato cyst nematodes.
US08808766B2 Herbal compositions for the control of hematophagous parasites
There is described an herbal hematophagous parasite control composition which comprises Picraena excelsa (Quassia), Foeniculum vulgare (fennel) and Azadirachta indica folium (Neem) provided that the composition is substantially free Juglans nigra folia (black walnut) and/or Allium sativim (garlic). There are also described a method of controlling hematophagous parasites.
US08808765B2 Cosmetic compositions and methods for using same to improve the aesthetic appearance of skin
The present invention relates to compositions useful in treating the various signs of dermatological aging in human skin. The present invention also relates to cosmetic compositions and methods of using such compositions that improve the aesthetic appearance of skin. Further, the present invention relates to methods of applying the compositions to the skin to effect treatment and to improve the aesthetic appearance of skin, particularly, by providing anti-aging benefits to the skin. Suitable anti-aging agents include 3,3′-thiodipropionic acid and/or its derivatives.
US08808761B2 Composition of skin external application containing rose extract and epigallocatechin gallate(EGCG)
The present invention relates to a composition of skin external application comprising rose extracts and epigallocatechin gallate (EGCG) as effective ingredients, more particularly to a composition of skin external application that contains rose extracts and EGCG, thereby promoting the synthesis of collagen fiber to promote superior skin elasticity and skin wrinkle improvement with long-lasting effect.
US08808760B2 Extract from palm leaves and a method for producing the same
A method for preparing an herbal extract comprises the steps of pre-treating foliages derive from a plant of Arecaceae family; extracting the pre-treated foliages by using a polar solvent; removing the pre-treated foliages from the used polar solvent; and concentrating the used polar solvent to acquire the herbal extract.
US08808759B1 Stabilized colloidal preparations, pre-mix and process for preparing skin care compositions, improved skin care composition, method for treating the skin
The present invention provides an approach for stabilizing and/or smoothing preparations containing colloidal materials, a pre-mix and a process for preparing skin care compositions and an improved skin care composition, said composition being presented in semi-solid or wet form and comprising more than 1% (w/w) of colloidal material. In one embodiment of the invention the composition comprises more than 1% of colloidal material such as colloidal oatmeal, said composition being particularly useful for treating the skin and ameliorating skin disorder symptoms.
US08808757B2 Herbal ointment for musculoskeletal and joint-related conditions
An herbal ointment. The herbal ointment may include about 45 weight percent of herb-infused oil, water or alcohol, or any desired combination thereof, about 30 weight percent purified water, about 10 weight percent emulsifier wax, about 5 weight percent menthol, about 3 weight percent dimethyl isosorbide, about 2 weight percent glycerin, about 2 weight percent hydrogenated methyl abietate, about 0.5 weight percent lonicera caprifolium and lonicera japanica extract, about 0.5 weight percent tocopherol, about 0.35 weight percent vanillyl butyl ether, about 0.35 weight percent xanthan gum, about 0.3 weight percent citric acid 50% aqueous solution, and about 0.25 weight percent menthyl lactate, the herb-infused oil, water or alcohol including a 1:5 dilution of herbal extracts in a solvent, wherein the herbal extracts are of German Chamomile (Matricaria recutita), Valerian (Valeriana officinalis), Ginger (Zingiber officinale Roscoe), Peppermint (Mentha×piperita), Feverfew (Tanacetum parthenium), and Lemon Balm (Melissa officinalis).
US08808753B2 Methods for treating pustular psoriasis
The invention is directed to methods for treating pustular conditions of the skin, for example, acne. Such methods utilize novel compositions, including but not limited to extraembryonic cytokine secreting cells (herein referred to as ECS cells), including, but not limited to, amnion-derived multipotent progenitor cells (herein referred to as AMP cells), conditioned media derived therefrom (herein referred to as amnion-derived cellular cytokine solution or ACCS), cell lysates derived therefrom, and cell products derived therefrom, each alone or in combination.
US08808752B2 Controlled release particles and method for producing the same
Controlled release particles are obtained by dissolving a hydrophobic antibiotic compound in a hydrophobic polymerizable vinyl monomer without the presence of a solvent, thereby preparing a hydrophobic solution, the hydrophobic antibiotic compound having a melting point of 100° C. or less, a polar term δp,compound of 2 to 8 [(J/cm3)1/2] of a solubility parameter (δ) and a hydrogen bonding term δh,compound of 5.5 to 9.5 [(J/cm3)1/2] of the solubility parameter (δ), the solubility parameter (δ) defined by Hansen and calculated by van Klevelen and Hoftyzer method; dispersing the hydrophobic solution in water; and polymerizing the polymerizable vinyl monomer in the presence of an oil-soluble initiator by radical polymerization, thereby producing a polymer having a polar term δp,polymer of 5 to 7 [(J/cm3)1/2] and a hydrogen bonding term δh,polymer of 8 to 10 [(J/cm3)1/2] of the solubility parameter (δ).
US08808745B2 Morphine polymer release system
A pharmaceutical composition for controlled release of an active substance is provided. The active substance is released into an aqueous medium by erosion of at least one surface of the composition. The composition comprises i) a matrix comprising a) polymer or a mixture of polymers, b) an active substance and, optionally, c) one or more pharmaceutically acceptable excipients, and ii) a coating.
US08808743B2 Benzonatate compositions and methods of use
Benzonatate resinates of weak acid ion exchange resins having the same distribution of butyl 4-aminobenzoate homologs as exist in the benzonatate listed in the F.D.A. Orange Book as Application No. N011210. These resinates, in simulated gastrointestinal dissolution, release essentially the same distribution of butyl-4 aminobenzoate homologs as exist in the benzonatate listed in the F.D.A. Orange Book as Application No. N011210.
US08808742B2 Compositions and methods for preparing and using same
This invention relates to compositions, methods for preparing the compositions and methods for treating or preventing diseases, comprising administering the compositions.
US08808738B2 Aliphatic amine polymer salts for tableting
The tablets, compositions and methods of the present invention, comprising a carbonate salt of an aliphatic amine polymer and s monovalent anion can prevent or ameliorate acidosis, in particular acidosis in patients with renal disease. The tablets and compositions of the present invention maintain a disintegration time of no greater than 30 minutes at 37° C. and at pH of at least 1 for a period of at least ten weeks at 60° C. Furthermore, the tablets are stable for extended periods of time without the need for specialized storage conditions.
US08808735B2 Fast wet-massing method for the preparation of calcium-containing compositions
The present invention relates to a novel process for the preparation of a granulate comprising a calcium-containing compound as an active substance. The method comprises a method for the preparation of a granulate comprising a calcium-containing compound as an active substance, the method comprising, i) feeding a granulation chamber with a composition comprising the calcium-containing compound, ii) wet-massing the composition with a granulation liquid optionally comprising a pharmaceutically acceptable binder for a time period of at the most 30 sec to obtain a wet granulate, iii) drying the thus obtained wet granulate. A granulate obtained by the present method is especially suitable in the preparation of solid dosage forms, in particular in the preparation of tablets.
US08808734B2 Cannabinoid formulations
The present invention provides stable, fast-acting liposomal and micelle formulations of cannabinoids that are suitable for pharmaceutical and nutraceutical applications.
US08808730B2 Composite material for tissue repair
The present disclosure provides a biocompatible composite and method for its use in repairing tissue defects, including defects in cartilage. The biocompatible composite includes a fibrous polymeric component and a polymerizable agent, which is capable of forming the biocompatible composite in situ at the site of a tissue defect. In embodiments, the repair site at which the biocompatible composite is to be applied may be treated with a priming agent, permitting polymerization of the polymerizable agent to the tissue located at the repair site.
US08808727B2 Posterior segment drug delivery
A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side.
US08808724B2 Antimicrobial coatings with preferred microstructure for medical devices
A medical device having an antimicrobial coating. The device has a first coating layer having an antimicrobial agent over at least part of the outer surfaces of the device. The first coating has an outer surface. There is a second discontinuous polymeric coating containing an antimicrobial agent, which is on top of and covering part of the outer surface of the first coating. The second discontinuous coating has a microstructure.
US08808721B2 Bed bug attractants and methods for trapping bed bugs
The present invention relates to compositions and methods for attracting bed bugs with novel attractants and new and improved methods to enable their use to attract, monitor or trap bed bugs for surveying, monitoring, mitigation and management purposes. Known mammal pheromones were discovered to be useful as bed bug kairomone attractants. A method of delivering non-volatile attractants by using the attractive heat source to heat and volatilize the attractants was discovered to be the optimal method to disseminate the kairomones. A new method of generating low levels of carbon dioxide is disclosed, and the combination of kairomones, carbon dioxide and heat is shown to attract bed bugs.
US08808711B2 Meningococcal outer membrane vesicles
OMVs targeted against specific epidemic strains can be highly effective in controlling localized outbreaks of disease. In combination with large-scale and reproducible manufacturing techniques, a vaccine can be rapidly produced after an outbreak. The invention provides a method for preparing a meningococcal outer membrane vesicle (OMV) vaccine, comprising the steps of: (i) identifying the serosubtype of a meningococcal strain associated with an outbreak of meningococcal meningitis; (ii) preparing OMVs from a meningococcal strain having the serosubtype identified in step (i) for use in vaccine manufacture. The method may comprise one or both of the further steps of (iii) formulating said OMVs as a vaccine; and (iv) distributing said vaccine in a geographical area affected by or likely to be affected by said outbreak. The meningococcal strain will typically be in serogroup B, but may be instead by in serogroup A, C, W135, Y, etc.
US08808709B2 Use of a modified poxvirus for the rapid induction of immunity against a poxvirus or other infectious agents
The present invention relates to the rapid induction of a protective immune response against infectious agents using a poxvirus. An immune response can be induced by administering the poxvirus 7 to 2 days prior to infection with the infections agents.
US08808708B2 Multivalent pneumococcal polysaccharide-protein conjugate composition
An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate contains a capsular polysaccharide prepared from a different serotype of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F) conjugated to a carrier protein. The immunogenic composition, formulated as a vaccine, increases coverage against pneumococcal disease in infants and young children globally, and provides coverage for serotypes 6A and 19A that is not dependent on the limitations of serogroup cross-protection.
US08808701B2 Methods of inhibiting the interaction of C5aR with C5a with anti-C5aR antibodies
The present invention is directed to humanized antibodies which bind the human C5a receptor and their use as therapeutic and diagnostic agents. The present invention is further directed toward nucleic acid sequences which encode said humanized antibodies, and their expression in recombinant host cells. In particular, the present invention is directed towards humanized antibodies derived from murine antibody 7F3 which specifically binds to the human C5a receptor.
US08808696B2 Methods for the treatment and prevention of abnormal cell proliferation using TACI-fusion molecules
The present invention provides methods and compositions for treatment of hyperproliferative disorders and cancers, including multiple myeloma and Waldenström's macroglobulinemia, comprising administering to a patient in need of the treatment a TACI-Ig fusion molecule in amount sufficient to suppress proliferation-inducing functions of BlyS and APRIL.
US08808695B2 Monoclonal antibodies to progastrin
The present invention provides progastrin-binding molecules that are useful therapeutically for passive immunization against progastrin in gastrin-promoted diseases or conditions. The progastrin-binding molecules are specific for progastrin but do not bind gastrin-17(G17), gastrin-34(G34), glycine-extended gastrin-17(G17-Gly) or glycine-extended gastrin-34(G34-Gly). The progastrin-binding molecules include monoclonal antibodies (MAbs) selective for sequences at the N-terminus and the C-terminus of the gastrin precursor molecule, progastrin.
US08808694B2 Therapeutic peptidomimetic macrocycles
The present invention provides biologically active peptidomimetic macrocycles for the treatment of cell proliferative disorders such as cancer and immunoproliferative disease.
US08808693B2 Semaphorin 3C (Sema3C) inhibitor therapeutics, methods, and uses
Provided are methods, uses and pharmaceutical compositions for treatment of prostate cancer with a SEMA3C inhibitor in a biologically effective amount sufficient to cause cell death of a prostate cancer cell or to inhibit proliferation of the prostate cancer cells. The prostate cancer may be an androgen receptor (AR) positive prostate cancer and the SEMA3C inhibitor may be selected from one or more of the following: an antibody, a SEMA3C peptide, an antisense RNA, a siRNA, a shRNA or a small molecule.
US08808692B2 Compositions comprising immunoreactive reagents and saponins, and methods of use thereof
The present invention relates to pharmaceutical compositions that are useful for the prevention and treatment of infectious diseases, primary and metastatic neoplastic diseases (i.e., cancer), neurodegenerative or amyloid diseases, or any other disease wherein the treatment of such disease would be improved by an enhanced immune response, and methods of formulating the compositions. The compositions comprise an immunoreactive reagent (i.e., an antigen binding protein comprising an antigen binding region and a region or regions of an antibody that mediate antibody dependent immunological processes) and a saponin. The present invention also relates to methods of using the compositions of the invention for the prevention and/or treatment of infectious diseases, primary and metastatic neoplastic diseases (i.e., cancer), neurodegenerative or amyloid diseases, or any other disease wherein the treatment of such disease would be improved by an enhanced immune response.
US08808690B2 Methods of treating infections originating from viruses in the herpesviridae family
Three RNases (ranpirnase, the second embodiment disclosed in U.S. Pat. No. 5,728,805, and recombinant Amphinase-2) are tested against identified herpesviridae infections. With some exceptions, quantitative PCR assays indicate that the RNases have anti-viral activity against many of these viruses.
US08808685B2 Method of treatment using organotypically cultured skin tissue comprising NIKS cells that express exogenous HIF-1α
The present invention relates to in vitro cultured skin tissue, and in particular to cultured skin tissue comprising exogenous genes encoding angiogenic growth factors. In some embodiments, the keratinocytes express exogenous angiopoietin-1, HIF-1α, or a member of the VEGF family, preferably VEGF-A. In particularly preferred embodiments, the keratinocytes are incorporated into cultured skin tissue.
US08808682B2 Method for inducing migration of adipose-derived adult stem cells
The present invention relates to the ability of adipose tissue-derived adult stem cells to migrate, and more particularly to the novel use of adipose tissue-derived adult stem cells primed with a specific chemokine or growth factor and their specific secretory products, which more effectively migrate to a disease site in vivo. The inventive composition containing either adipose-derived adult stem cells or adipose tissue-derived adult stem cells primed with a specific chemokine or growth factor can be administered by a simple method such as intravenous administration and are able to induce the targeting of the stem cells to a disease site. Thus, the composition is useful as a cell therapeutic agent.
US08808672B2 Liquid cosmetic
To provide a liquid cosmetic which is loaded into a liquid applicator having an applying part and suitably used as a cosmetic for eye-makeup around the eyes, the liquid cosmetic comprises, at least, 1 to 20% by mass of high-brightness particles, 2 to 10% by mass of film-forming resin, 0.3% by mass or more of an anionic polymer compound having a thickening effect, and water, and is configured such that the viscosity at 25° C. and a shear rate of 76.8 s−1 in an EMD type viscometer falls within the range of 250 to 1,000 mPa·s.
US08808669B2 Gastroretentive, extended release composition of therapeutic agent
A gastroretentive, extended release composition which floats and swells at acidic pH prevalent in the stomach. The composition includes a pH dependent graft copolymer, a gellable polymer, a therapeutic agent, a gas generating system and pharmaceutically acceptable ingredients. The disclosed composition is useful to deliver the therapeutic agent within the stomach for an extended period of time.
US08808667B2 Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses
The present invention relates to the use of a milled homogenate and/or a suspension and/or a cell lysate, stemming from a tumor resistant to at least one anti-tumoral compound in order to immunize and generate in vitro an antibody, or one of its functional fragments, directed against a tumoral antigen specifically expressed at the surface of said resistant tumor and being possibly involved in the resistance of said resistant tumor. More particularly, the present invention is directed to such antibodies obtained by applying the method, such as the antibodies 1A6, 1A9, 2E11, 3C11 and 3G7, as well as to their use for treating cancer.
US08808655B2 Bifunctional active sites for adsorption of NOx
Immobilized nitronyl nitroxide active sites on the surface of a porous inorganic oxide support act as efficient and rapid oxidants for NO, reacting with >99% of the NO under flow conditions through a packed bed; and, in a parallel configuration with nitroxyl radical active sites, act to remove >99% of both NO and NO2 from a gas mixture, with >95% of the active sites participating in NOx trapping.
US08808654B2 Process for sulfur removal from refinery off gas
Organic sulfur compounds contained in refinery off gas streams having either high ort low concentrations of olefins are converted to hydrogen sulfides which can be then be removed using conventional amine treating systems. The process uses a catalytic reactor with or without a hydrotreater depending on the olefin concentration of the off gas stream. The catalytic reactor operates in a hydrogenation mode or an oxidation mode to convert a majority of organic sulfur compounds into hydrogen sulfides.
US08808651B2 Industrial salt and apparatus and process for producing industrial salt
To provide a low price industrial salt by reducing facility and operation costs without electro-deposition and crystallization and through reduction in quantity of chemicals used. An industrial salt S obtained by the steps of: extracting a part of combustion gas from a kiln exhaust gas passage running from an inlet end 12b of a cement kiln 12 to a bottom cyclone 13; recovering dust D from the extracted gas G2 and washing recovered dust; and drying a filtrate L1 after the washing in a gas stream. The industrial salt can be obtained by removing a calcium component from the filtrate and drying the filtrate from which the calcium component is removed in a gas stream. Further, from the filtrate can be removed sulfate radical, and drying the filtrate from which the calcium component is removed in a gas stream to obtain the industrial salt. For the drying can be used an exhaust gas discharged from a clinker cooler 12a and a spray drier 43 may be used for the drying. Drying in a stream provides industrial salt whose particle size is larger or equal to 20 μm and smaller or equal to 500 μm.