| Document | Document Title |
|---|---|
| US08773151B2 |
Method and device for multichannel multifrequency analysis of an object
A method for multichannel multifrequency analysis of an object, applying a set of excitation signals to the object and sampling the response signal from the object, using uniform and non-uniform undersampling. Non-uniform sampling of the response signal is performed, i.e., the sampling is performed for two or more different frequencies in one observation time slot. Also, uniform sampling of the response signal is performed, i.e., the sampling of a signal, corresponding to one frequency, is performed for two or more channels within one observation time slot and then sampling the same signal for another frequency for two or more channels within the next observation time slot. |
| US08773148B2 |
Centroid position detector device and wearing type action assistance device including centroid position detector device
Load measuring parts 50 and 52 are provided with reaction sensors 50a, 50b, 52a and 52b to measure loads at two positions, the tiptoe and the heel, on each sole of right and left feet of a wearing person 12. The reaction sensor 50a detects a reaction force to a load on a front side of the right foot (right tiptoe), the reaction sensor 50b detects a reaction force to a load on a rear side of the right foot (right heel), the reaction sensor 52a detects a reaction force to a load on a front side of the left foot (left tiptoe), and the reaction sensor 52b detects a reaction force to a load on a rear side of the left foot (left heel). The reaction sensors 50a, 50b, 52a and 52b are arranged to detect, based on a change of a capacitance, the loads on the right and left feet during a walk action. A change of the load accompanied with a shift of the weight and a contact between the wearing person's foot and the ground can be detected. |
| US08773140B2 |
System and method for inspection of electrical circuits
A system for inspection of electrical circuits including a calibration subsystem operative to apply a time varying voltage to an electrical circuit being inspected during calibration and to sense differences in an electrical state at various different locations in the electrical circuit being inspected, thereby providing an indication of location of defects therein. |
| US08773137B2 |
Method and device to detect the flame in a burner operating on a solid, liquid or gaseous combustible
A method for flame sensing in a solid, liquid or gaseous fuel burner, the flame generated at an ionization electrode, the flame presence resulting in an ionizing effect on the electrode. The electrode is powered by an alternating voltage signal. The ionization phenomenon generates in the electrode a direct current. The current being sensed by a suitable sensing circuit including a control unit. This signal generator being of relatively low internal impedance to enable the measured generated current to have a high value compared with that normally used and of waveform to tend to limit the value of the direct current flowing through the electrode. The sensing and control circuit being such as to enable the presence of a parasitic current on the flame sensing electrode to be measured. A device for implementing the method is also disclosed. |
| US08773136B2 |
Method for evaluating the ability of a battery to start
The charge state of a battery powering a starter of a motor vehicle is evaluated to determine whether the battery voltage is sufficiently high to re-start an internal combustion engine during a stop/start operating mode. The engine is operated to drive a generator so that the generator output voltage is at a level below a setpoint value for a time period. At the end of the time period, the battery voltage is measured and if it exceeds a threshold voltage the battery charge state is determined to be sufficient to re-start the engine. The threshold voltage is approximately equal to the rated battery voltage. If the measured battery voltage is below the threshold voltage value, indicating that the battery will not have sufficient charge to re-start the motor, automatic shut-off of the engine when the vehicle stops is suppressed. |
| US08773135B2 |
Resistivity imaging using phase sensitive detection with a floating reference signal
A device, method and system for measuring characteristics of a geologic formation using a floating reference signal having a mud chamber, an electrode disposed within the mud chamber, and an electrically conductive plate disposed within the mud chamber, the plate separated from the electrode. An alternating current source is provided on the electrode, whereby an electric field is be maintained between the electrode and the conductive plate. An opening in the mud chamber allows drilling fluids to pass there through. |
| US08773133B1 |
Adaptive multichannel locator system for multiple proximity detection
Man-portable locator systems for locating buried or otherwise inaccessible pipes, conduits, cables, wires and inserted transmitters using detector arrays and stochastic signal processing and similar techniques to analyze and display multiple target objects at differing frequencies in a layered user interface (UI) are described. In one embodiment, the locator UI may be adapted to present a target plurality sorted by proximity of target conductor to the locator operator together with other useful information specifying the multiple objects, frequencies and changes in the subterranean landscape by means of a useful combination of graphical, numeric and acoustic representations. |
| US08773128B2 |
Method and apparatus for enhancing signal in magnetic resonance imaging
A method and an apparatus for enhancing signals in magnetic resonance imaging are provided. The method includes the following steps. Applying one or more than one RF pulse, which carries at least two frequency components, and a slice/slab selection gradient to a subject, so that at least two slices/slabs of the subject respectively corresponding to the at least two frequency components are excited simultaneously. Applying a plurality of spatial encoding gradients and one or more than one separation gradients for separating the at least two slices/slabs. Receiving a plurality of responsive RF signals excited from the subject. The responsive RF signals are restored according to a signal restoration function. |
| US08773122B2 |
Hall element control circuit
A first terminal supplies the bias voltage to a high-potential-side input terminal of a hall element. A second terminal supplies the ground potential to a low-potential-side input terminal of the hall element. A P-channel type transistor is configured such that the source terminal is connected to the power supply potential and the drain terminal is connected to the first terminal. An operational amplifier differentially amplifies the voltage between a predetermined set voltage and the voltage at the first terminal so as to control the gate voltage of the P-channel type transistor. |
| US08773116B2 |
Rotation angle detecting device
A rotation angle detecting device includes a rotating body rotating according to rotation of a vehicle pedal; a magnet attached to the rotating body; a magnetism detection element disposed facing the magnet at a predetermined interval from the magnet; and a first control circuit connected to the magnetism detection element. The center of the magnet is placed at the rotation center of the rotating body. The magnetism detection element detects magnetism of the magnet to output a detection signal. The first control circuit outputs an angle signal corresponding to a rotation angle of the rotating body according to the detection signal, and outputs a switching signal according to the rotation angle of the rotating body. The rotation angle detecting device reliably detects a rotation angle and turns a stop lamp on and off for example with a simple structure. |
| US08773114B2 |
Apparatus for detecting displacement of electromagnetic actuator
A displacement detecting apparatus of an electromagnetic actuator, including: an electromagnetic actuator including: a movable core; a drive coil which causes a displacement of the movable core; and a detection coil disposed at a position where a mutual coupling coefficient with the drive coil changes with the displacement, the actuator transmitting a drive force of the movable core to a mechanical system; a drive portion for supplying a drive current to the drive coil on the basis of a pulse width modulation signal; and a displacement detecting portion to which an output voltage of the detection coil is inputted, for outputting a displacement detection signal, wherein the displacement detecting portion includes: a sampling-signal generating portion for generating a sampling signal in synchronism with the pulse width modulation signal; and a synchronous sampling portion for outputting the displacement detection signal by sampling the output voltage in synchronism with the sampling signal. |
| US08773112B2 |
Current sensor
To produce an insulated current sensor for slaving power devices in the field of avionics, use is made of a magnetic core through which there passes an element traversed by a current to be measured. The magnetic core comprises a secondary winding across the terminals of which are connected an oscillator and a measurement device. The cooperation of the oscillator and of the measurement device makes it possible to circumvent all the traditional drifting of current sensors. |
| US08773109B2 |
System, method and device for monitoring capacitor cells connected in series in a capacitor module
A system for monitoring a plurality of capacitor cells connected in series in a capacitor module which are used as electrical energy stores in an energy storage device and which can be charged in same by a charge current flowing through all the capacitor cells or discharged by a discharge current. The system includes a measuring unit which can determine the voltages applied to the individual capacitor cells by measuring voltages, an evaluation unit which sets a nominal voltage for the capacitor cells, and at least one discharge branch connectable to each capacitor cell and controllable by a discharge control unit which discharges a respective capacitor cell onto said discharge branch depending upon the set nominal voltage and the applied voltage. |
| US08773108B2 |
System, method, and apparatus for a safe powerline communications instrumentation front-end
A safe powerline communications instrumentation front end device including a voltage input for receiving a line voltage from a powerline, a voltage reducer for reducing the voltage of the line voltage, a filtering system for extracting a Power Line Communications (PLC) signal from the line voltage, and an analog output for outputting the PLC signal as an analog signal for communications test equipment. |
| US08773105B1 |
Voltage regulators with large spike rejection
A voltage regulator includes a master circuit, first and second filters, and a slave circuit. The master circuit provides a second reference voltage based on a first reference voltage and a supply voltage. The first filter provides a filtered second reference voltage based on the second reference voltage. The second filter provides a filtered supply voltage based on the supply voltage. The slave circuit provides a third reference voltage based on the filtered second reference voltage and the filtered supply voltage. The second filter includes an NMOS transistor and a capacitor. The gate and the drain of the NMOS transistor receive the supply voltage. A first terminal of the capacitor is electrically coupled to a source of the NMOS transistor. A second terminal of the capacitor is electrically coupled to ground. The source of the NMOS transistor provides the filtered supply voltage. |
| US08773096B2 |
Apparatuses and methods responsive to output variations in voltage regulators
A voltage regulator includes an amplifier to generate a difference voltage responsive to a comparison of a reference voltage and a feedback voltage. An output driver is coupled to the amplifier and drives a regulated output voltage responsive to the difference voltage. An impedance circuit is coupled between the output driver and a low power source and establishes the feedback voltage responsive to a current through the impedance circuit. A variation detector is operably coupled between the regulated output voltage and the difference voltage and is configured to modify the difference voltage. In some embodiments, the difference voltage is modified responsive to a rapid change of the regulated output voltage capacitively coupled to the variation detector. In other embodiments, the difference voltage is modified responsive to a rapid change of the feedback voltage capacitively coupled to the variation detector. |
| US08773094B2 |
Alternating current line emulator
An alternating current (AC) line emulator includes an AC power supply and an automatic regulating load. The AC power supply is used for providing an AC line frequency and an AC line voltage. The automatic regulating load is coupled between the AC power supply and a grid-connected power generation system for functioning as a test load of the grid-connected power generation system, and preventing current from reversing to the AC power supply and shutting down the AC power supply. When the grid-connected power system is tested, power consumption of the automatic regulating load is equal to a sum of output power of the grid-connected power generation system and output power of the AC power supply. |
| US08773091B2 |
Dead time modulation technique for the improvement of power conversion efficiency
A method for generating an output voltage from an input voltage with a switched mode power supply at a switching frequency is provided. At the switching frequency, a transistor within a switching circuit is deactivated so as to enter into a dead time interval, where the switching circuit includes a switching node. A negative inductor current is used during the dead time interval so as to slew the switching node, where switching frequency and the input voltage are sufficiently large so as to overcome a loss incurred by using the negative inductor current. |
| US08773090B2 |
Voltage regulator with adaptive hysteretic control
A voltage regulator with adaptive hysteretic control. The voltage regulator may include a top switch (e.g., MOSFET) configured to couple a power supply supplying an input voltage to a load. An adaptive hysteretic control circuit of the voltage regulator may turn on the top switch when the feedback voltage reaches the low threshold and turn off the top switch when the feedback voltage reaches the high threshold. The adaptive hysteretic control circuit may adjust the upper and lower threshold to make the voltage regulator working like a constant on time control circuit in steady state. When a step down transient happens, the top switch could be turned off when the output voltage reaches the upper threshold, and when a step up transient happens, the top switch could be turned on when the output voltage reaches the lower threshold, it makes the voltage regulator working like a hysteretic control circuit. |
| US08773089B2 |
Regulator capable of rapidly recovering an output voltage and a load current thereof
A regulator includes a first amplifier, a second amplifier, a current control circuit, a first P-type metal-oxide-semiconductor transistor, a second P-type metal-oxide-semiconductor transistor, and a feedback circuit. The current control circuit includes a controller and at least one switch, and a second terminal of the first P-type metal-oxide-semiconductor transistor is coupled to a second terminal of the second P-type metal-oxide-semiconductor transistor. The regulator utilizes the controller to turn off the at least one switch during operation of the regulator in a light load mode, and the regulator utilizes the controller to turn on the at least one switch in turn when the regulator changes from the light load mode to a heavy load mode. Thus, the regulator can quickly recover a load current in the heavy load mode. |
| US08773087B2 |
Power supply circuit having switched capacitor units
The invention relates to a power supply circuit (10) and methods for supplying electrical power to at least one load output. The circuit comprises a main power supply unit (12) with a voltage input (14), a main switching element (26) and a reactive element (28). The switching element (26) is controllable to deliver an output voltage or current (I out). Output units (20a, 20b, 20c) with load outputs are connected to a main power supply unit (12). In order to drive loads connected to the load outputs, e.g. LEDs, OLEDs or laser diodes, with exact pulses, each output unit (20a, 20b, 20c) has a load switching element (38) to connect or disconnect the main power supply unit (12) to or from the load output. There are further provided switched capacitor units (34), each with a capacitor (C) and a capacitor switching element (40). The capacitor units may be operated such that the capacitors remain essentially charged at different voltage levels. According to a second aspect of the invention, each output unit (20a, 20b, 20c) has a switched capacitor unit (34) with a capacitor (C) and a capacitor switching element (40) connected to the load output. The load switching element (38) and the capacitor switching elements (40) are controlled synchronously. |
| US08773084B2 |
Buck-boost converter using timers for mode transition control
A DC-to-DC, buck-boost voltage converter includes a duty cycle controller configured to generate control signals for a buck driver configured to drive first and second buck switching transistors at a buck duty cycle and to generate control signals for a boost driver configured to drive first and second boost switching transistors at a boost duty cycle. The duty cycle controller includes at least a duty cycle timer and an offset timer where the duty cycle controller applies the duty cycle timer and the offset timer to control transitions between the buck, the buck-boost and the boost operation modes of the voltage converter. |
| US08773081B2 |
Controller for controlling power generator driven by rotational power of engine
In a controller, a voltage controller operates, in an initial excitation mode, to turn selectively on and off a switch to supply an excitation current as an initial excitation current to the field winding, and operates, in a power generation mode, to selectively increase and reduce the excitation current to be supplied to the field winding to regulate an output voltage of the power generator to a target value. A mode-shift determiner determines, while the voltage controller operates in the initial excitation mode, whether to shift an operation mode of the voltage controller from the initial excitation mode to the power generation mode based on: a measured rotation number of a rotor, a threshold rotation number of the rotor, and a preset time period, the time period being equal to or longer than an expected maximum value of cycle of pulsations of rotation of the engine. |
| US08773079B2 |
Method of and plant for storage and retrieval of electrical energy
A series of capacitors arranged in a way to prevent build up of electric flux between the plates of adjacent capacitors. The capacitors are electrically wired and provided with means to charge them by deriving electrical energy from a power source. The capacitors are also provided with means to discharge them one at a time at predetermined interval and during discharging, momentarily activate a motor. As the motor is activated during the discharge event of a capacitor it rotates a shaft which has means to engage and rotate a second shaft mounted with a flywheel. The first shaft will have means to disengage itself from the second shaft in between the discharge events of any two capacitors. The second shaft is connected to a third shaft through a gear box allowing it to rotate at desired rpm. The third shaft is also connected to a generator to produce electricity. Before the start of the process of discharging the capacitors the second shaft starts rotating with the help of a starter and a starter gear to overcome the inertia of rest of the flywheel. |
| US08773076B2 |
Battery management system, method of removing polarization voltage of battery, and estimating state of charge of battery
A battery management system according to an exemplary embodiment of the present invention includes: a current measuring unit for sampling a charge current and a discharge current of a battery; a charge and discharge amount calculator for calculating a charge and discharge amount corresponding to a difference between the sampled charge current and the sampled discharge current; a polarization voltage calculator for calculating a polarization voltage corresponding to the charge and discharge amount and a temperature of the battery; and a pulse generator for applying a polarization voltage reset pulse for the battery to remove the polarization voltage. |
| US08773072B2 |
Refuelable storage battery
A reversible storage system for electric energy, including charging or discharging surfaces as a positive collector terminal and a charging or discharging area as a negative collector terminal and a flow electrode with a pumpable dispersion with particles storing electric energy and at least one supply line and at least one drain line for the pumpable dispersion. The pumpable dispersion includes particles storing electric energy in a capacitive and/or chemical fashion, having an average grain size distribution: 1 nM to 500 μm. For chemically storing particles, the negative and the positive collector terminals have a planar shape with a single exterior closed border and with their planar sides each contacting an ion-selective diaphragm or spacers, and the pumpable dispersion is arranged on a side facing away from the planar side of the respective collector, contacting the ion-selective diaphragm or spacers, and the dispersion at least partially penetrates the respective collector. |
| US08773071B2 |
System and method for cell voltage balancing
A method for cell voltage balancing is disclosed. A plurality of cells is coupled to a plurality of cell interface circuits, and the cell interface circuits are driven with a balancing transformer such that a balancing current flows between the cell interface circuits. Control gates of the cell interface circuits are driven with a gate drive transformer such that two adjacent circuits of the cell interface circuits are activated with opposite phase. |
| US08773067B2 |
Charging base with drainage features
A charging base has a bottom case, a printed circuit board (PCB) and a top case. The bottom case includes at least one drainage hole. The PCB is mounted in the bottom case and includes a mounting hole, a positioning block and charging terminals. The positioning block is attached to the PCB and has through holes. The charging terminals are secured to the positioning block and have apertures. The top case covers the bottom case and includes terminal holes and a top enclosed wall. The top enclosed wall is secured around the positioning block. Therefore, when water accidentally enters the charging base via the terminal holes, the water will sequentially flow through the apertures of the charging terminals, the through holes of the positioning block and the mounting hole of the PCB and subsequently drain out of the drainage hole of the bottom case. |
| US08773064B2 |
Reverse charging prevention system for mild hybrid vehicle
A charging system for a hybrid vehicle which prevents a super capacitor from being reverse charged. In the illustrative charging system a DC-DC converter is connected to the inverter and configured to receive the DC electricity from the inverter and drop voltage. A battery is configured to receive the DC electricity from the DC-DC converter and to be charged by the DC electricity. Finally, a means for preventing reverse charging is mounted on a path between the super capacitor and the battery and is configured to prevent energy from flowing from the battery to the super capacitor. |
| US08773062B2 |
Polyphase electric motor
A polyphase electric motor has a rotor, a stator with a plurality of slots, a plurality of main windings and a plurality of auxiliary windings installed in slots of the stator, and a main winding and an auxiliary winding that correspond to a selected phase of an alternating current power source. The auxiliary windings are connected to the motor terminals through a plurality of capacitors, and the auxiliary windings and corresponding capacitors are connected in parallel to the main windings. The main winding and the auxiliary winding of the selected phase are offset by about 60 to about 120 electrical degrees. A power of the plurality of main windings is at least 75% of a power of the polyphase electric motor at full load rating and the power of the plurality of main windings is motoring at 25% of the full load rating. |
| US08773060B2 |
Brushless motor drive device and drive method
The invention relates to a brushless motor drive device that performs switching determination of energization modes of a three-phase brushless motor according to a sensorless method, and a drive method thereof. A pulse induced voltage induced in a non-energized phase of three phases by a pulse voltage is compared with a threshold to determine the switching timing of the energization modes. Here, by limiting a duty ratio of a voltage application to equal to or greater than a lower limit, a situation in which the pulse induced voltage is sampled while the pulse induced voltage is oscillating is avoided, and a situation in which the pulse induced voltage falls below a voltage detection resolution is avoided. As a result, determination of energization mode switching timing based on a pulse induced voltage can be performed more stably. |
| US08773057B2 |
Motor control unit and electric power steering system
An ECU that controls a motor includes: a target current value setting unit setting a target current; a voltage detecting unit detecting a detected voltage on the basis of a detection signal from a voltage sensor; a voltage calculation unit calculating an estimated voltage on the basis of a power supply voltage of a battery; and an induced voltage observer calculating an induced voltage generated at the motor using an inter-terminal voltage based on the estimated voltage when the target current is set to a value other than zero; whereas the induced voltage observer calculates the induced voltage using an inter-terminal voltage based on the detected voltage when the target current is set to zero. |
| US08773054B2 |
Hybrid electric vehicle system and method of controlling the same
The present invention is directed to a method of estimating a motor rotation angle that does not affect precision of a detected angle of a crank angle sensor, which is an alternative sensor, when abnormality occurs in a resolver and a peripheral circuit, and performing a motor control without failure of an inverter or peripheral device. A vehicle system includes a motor, a resolver detecting a rotor rotation angle of the motor, a motor control circuit controlling the motor based on information on rotor rotation angle and torque command value, an engine connected to the motor through a crankshaft, and a crankshaft sensor detecting revolutions of the crankshaft, in which the motor control circuit estimates rotor rotation angle based on a variation rate of the number of revolutions of the crankshaft when abnormality of the resolver is detected, and performs a weak field control based on estimated rotor rotation angle. |
| US08773040B2 |
Indicator drive circuit
An indicator drive circuit includes a current mirror circuit including a first transistor located at a control side and a second transistor located at a controlled side, a current through the current mirror circuit being switched by an external control signal, a current source adapted to feed a control current to the first transistor of the current mirror circuit, and a switching element adapted to be driven by a current through the second transistor of the current mirror circuit and to switch on or off an indicator light source. The current source includes two transistors cascode-connected. |
| US08773036B2 |
Projector
A projector that outputs a first picture and a second picture alternately, wherein a control section performs first control and second control, controls a discharge lamp driving section. In the first control and the second control, the absolute value of a drive current is relatively small in a first period and relatively large in a second period. In the first control, the energy provided to a first electrode in the second period is greater than the energy provided to the second electrode in the second period. In the second control, the energy provided to the second electrode in the second period is greater than the energy provided to the first electrode in the second period. |
| US08773034B2 |
Power supply system for electronic loads
The invention relates to a power supply system and a method for providing a load (L) with electrical power from either a first or a second AC grid source (10L, 10H) that supply different first and second AC voltages, respectively. In a particular example, said grid sources may belong to the US and the European mains, respectively, and the load may be a lamp with mains compatible LEDs (Ch1-Ch4). The power supply system comprises a first and a second connector device (30L, 30H) for connecting a converter circuit (20) to the first or the second AC grid source (10L, 10H), respectively. Moreover, the second connector device (30H) comprises a transformation circuit (D1-D4) for transforming the second AC voltage such that it yields a similar output voltage of the converter circuit (20) as the first AC voltage. In a particular example, the converter circuit (20) may comprise a rectifier (D5-D8, C1, C2) with voltage doubling function, and the second connector device (30H) may comprise a rectifier (D1-D4) while the first connector device (30L) is a simple cable. |
| US08773033B2 |
Driving method for backlight unit of liquid crystal display and system thereof
A method for driving the backlight unit of the liquid crystal display includes: comparing the strength of a soft start signal with a predetermined signal through a comparator circuit, and generating a first comparison signal or a second comparison signal according to the comparison result; outputting a first frequency from a frequency modulation circuit according to the first comparison signal; and increasing the rising rate of the output voltage of a boost converter according to the first frequency. Therefore, the rising rate of the output voltage is increased, thereby solving the screen-flickering problem. |
| US08773028B2 |
Direction indication lamp control device, direction indication device, and method of controlling direction indication device
A direction indication lamp control device includes: a pulse signal generation unit that generates a pulse signal; a current control element having one end to which power supply voltage is supplied, a control terminal to which the pulse signal is supplied, and the other end which outputs a drive current, the other end of the current control element being connected to one end of an external direction indication switch, and the other end of the direction indication switch being connected to a direction indication lamp; and a leak detection unit that causes the pulse signal generation unit to decrease the amplitude of the pulse signal in a case where the drive current corresponding to a pulse wave of the pulse signal is equal to or less than a leak detection current value during a leak detection period. |
| US08773026B2 |
Light tube and power supply circuit
A light tube for illumination by a power supply circuit includes a bulb portion and at least one end cap disposed on the bulb portion. A plurality of light emitting diodes is disposed inside the bulb portion for illuminating in response to electrical current to be received from the power supply circuit. The light emitting diodes are arranged in spaced-apart groupings. |
| US08773020B2 |
Apparatus for forming a magnetic field and methods of use thereof
Apparatus for forming a magnetic field and methods of use thereof are provided herein. In some embodiments, a plurality of coils having substantially similar dimensions disposed about a process chamber in a symmetric pattern centered about a central axis of the process chamber, wherein the plurality of coils are configured to produce a magnetic field having a plurality of magnetic field lines that are substantially planar and substantially parallel. In some embodiments, the plurality of coils comprises eight coils disposed about the process chamber, wherein each of the eight coils is offset by an angle of about 45 degrees from respective adjacent coils of the eight coils. |
| US08773019B2 |
Feedback control and coherency of multiple power supplies in radio frequency power delivery systems for pulsed mode schemes in thin film processing
A RF power supply system for delivering periodic RF power to a load. A power amplifier outputs a RF signal to the load. A sensor measures the RF signal provided to the load and outputs signals that vary in accordance with the RF signal. A first feedback loop enables control the RF signal based upon power determined in accordance with output from the sensor. A second feedback loop enables control the RF signal based upon energy measured in accordance with signals output from the sensor. Energy amplitude and duration provide control values for varying the RF signal. The control system and techniques are applicable to both pulsed RF power supplies and in various instances to continuous wave power supplies. |
| US08773016B2 |
Display apparatus including light emitting elements and a light shielding portion disposed on the light emitting elements and an electronic device including same
A display apparatus, includes: a substrate; a plural light emitting elements provided on the substrate and each formed from a lower electrode, a light emitting function layer and an upper layer stacked in this order; a partition for element isolation provided on the substrate and having a plural apertures individually corresponding to the light emitting elements; and a black matrix disposed on the light extraction side of the light emitting elements and having a shape with which the black matrix covers over portions. Each of the apertures of the partition having a side wall is formed in such a tapering shape that the aperture width increases toward the light extraction side of the light emitting elements. The black matrix is provided in such a manner as to cover over an upper edge portion of the tapering shape on at least one side which defines each aperture of the partition. |
| US08773014B2 |
Organic light emitting diode and method for producing an organic light emitting diode
An organic light-emitting diode includes an organic light-emitting layer located between a transparent electrode and one other electrode on a substrate. In some embodiments at least one of the transparent electrode and the other electrode has two layers. The two layers include a structured layer, which is a charge carrier injection layer, and a conductive second layer into which the first layer is embedded. In some embodiments the organic light-emitting layer includes a structured charge carrier blocking layer. |
| US08773010B2 |
Display device
A display device includes at least one light-emitting device and a patterned color filter layer. The light-emitting device is used to provide a white light having a white point chromaticity coordinate (Wx, Wy) where 0.23 |
| US08773009B2 |
Illumination apparatus to reduce insect attractancy
An illumination apparatus includes an LED light source including one or more LEDs. A spectrum of lights emitted from the LED light source has a first peak wavelength in a wavelength band ranging from 380 nm to 470 nm and a second peak wavelength in a wavelength band ranging from 500 nm to 700 nm, and a half width of the first peak wavelength is set to be equal to or less than 20 nm. |
| US08773008B2 |
Discharge lamp bulb having metal band supported by support portion
A discharge lamp bulb includes an arc tube having: a pair of electrodes that are opposed to each other inside a luminous tube; an outer tube having the luminous tube therein; a pair of lead wires connected to the electrodes; and a metal band mounted on an outer periphery of the outer tube, a support plug having: a plug body having a hollow, inner cylindrical section therein that opens at a front end; an arc-tube support portion mounted on a front-end edge of the inner cylindrical section; and a flange, and a lead support wire extending outside the outer tube in the longitudinal direction and connecting one of the lead wires with the support plug, wherein a front-end face of the inner cylindrical section is substantially flush with a front-end face of the flange or positioned on a back-end side with respect to the front-end face of the flange. |
| US08773005B2 |
Quartz-crystal devices exhibiting reduced electrical impedance
Quartz-crystal vibrating devices are disclosed, including vibrating and frame portions separated by a through-slot. An edge surface of the slot has a protrusion preventing unwanted formation of artifact “electrodes.” The vibrating portion and frame are made of AT-cut quartz as a unit. A joining portion couples the frame and vibrating portion together across the through-slot. A package base has two external electrodes. A third frame region has first and second plane surfaces. The protrusion projects toward the vibrating portion and has first and/or second sloped surfaces. First and second extraction electrodes extend from respective excitation electrodes via respective joining portions to respective external electrodes. The extraction electrodes pass across the first plane surface and first sloped surface or across the second plane surface and second slanted surface. |
| US08773004B2 |
Circuit for optimizing the recovery of vibratory energy by a mechanical/electrical converter
An apparatus for converting mechanical vibration energy into electrical energy includes a converter that, when subjected to vibrations, generates an electrical potential difference, and an electrical circuit connected to terminals of the converter. The circuit includes a first arm and a second arm parallel to the first warm. The first arm has a first variable-capacitance capacitor system. The second arm includes an electrical load to be powered. A second variable-capacitance capacitor is series-connected with the electrical load. A control circuit is configured to modify respective capacitance values of the first and second capacitor systems so as to modify the converter's mechanical resonance frequency. |
| US08773003B2 |
Thermoelectric generator
A thermoelectric generator including a sheet of a deformable material containing closed cavities, each of which contains a drop of a vaporizable liquid, and a mechanism for transforming into electricity the power resulting from the deformation of the sheet linked to the evaporation/condensation of the liquid. |
| US08773000B2 |
Acoustic wave device
An acoustic wave device includes a supporting substrate made of lithium tantalate, an element substrate made of lithium tantalate, and having a lower surface bonded to and arranged on an upper surface of the supporting substrate, and a comb-like electrode formed on an upper surface of the element substrate and exciting an acoustic wave. A propagation direction of the acoustic wave in the element substrate is an X-axis of the acoustic wave. A normal direction of the upper surface of the supporting substrate is an X-axis or a Y-axis of the supporting substrate. The propagation direction of the acoustic wave is not parallel to a Z-axis of the supporting substrate. |
| US08772998B2 |
Electric machine
The device comprises a single circular row of permanent magnetic poles and a circular row of electromagnets, magnetic-force-conducting elements of which have central polar part and two lateral polar parts connected to the central polar part and spaced from opposing (in the direction which is essentially perpendicular to the rotation axis) sides of the central polar part. Winding is situated upon central polar part. The part of winding positioned between the polar parts of the magnetic-force-conducting element is more than half the length of the whole winding. Central polar part may have at least one groove. The distance between the centers of adjacent polar surfaces of the magnetic-force-conducting element is set depending on the angle between the magnetic poles in the circular row. The angular dimension of the polar surface of the lateral polar part depends on the angular dimension of the polar surface of the central polar part. |
| US08772994B2 |
Permanent-magnet (PM) rotors and systems
Permanent-magnet (PM) rotors, rotor components, and machines using PM rotors, where the PM rotors have internally coupled PM bulks and/or are configured to have a non-uniform air gap between the rotor and a stator. |
| US08772993B2 |
Electric motor with adhesively bonded ring magnet
An electric motor (20) has a stator (30) and a rotor (26). The latter is equipped with a cup-like rotor part (56) and with a ring magnet (60) adhesively bonded therein, which magnet has an outer circumference (61) on which are provided elevations (84) and depressions (86) that extend at least partly in the longitudinal direction of the ring magnet (60). The outer circumference (61) of the ring magnet (60), that faces toward the cup-like rotor part (56) after assembly, is formed with at least one opening or channel (68; 69, 88), extending in a circumferential direction, that is connected to at least a plurality of the flat depressions (86). Positive mechanical engagement between adhesive and ring magnet enhances durability, and discourages any tendency toward relative rotation between the magnet (60) and the cup-like rotor part (56). |
| US08772992B2 |
Airfoil-magnetic hybrid bearing and a control system thereof
An airfoil-magnetic hybrid bearing, which is a combination of a magnetic bearing and airfoil bearing includes a housing, an airfoil bearing, a magnetic bearing, coils, and a coupling segment. The housing is around a rotating shaft of a rotation device. The airfoil bearing is positioned between the housing and the rotating shaft to form dynamic pressure to levitate the rotating shaft during rotation of the rotating shaft. The magnetic bearing includes cores positioned radially between inner surface of the housing and outer surface of the airfoil bearing. The cores are projected to the center of the rotating shaft. The coils wound to the cores to levitate the rotating shaft using a magnetic attractive force generated by a current application thereto. The coupling segment is configured to couple the airfoil bearing to the magnetic bearing directly. |
| US08772988B2 |
Stator structure for electric machine
An electric machine includes a stator stack of laminations, pierced with a cylindrical passage for housing a rotatable rotor therein. The stator includes a magnetic circuit of laminations stacked between first and second terminal faces crossed by the passage and by a series of slots housing conductors, which are folded over to form coils. An electrically insulating reinforcing wedge piece is interposed between an internal wall of a first tubular end and a corresponding portion of a block of resin surrounding a region of winding heads of the conductors, which follow a looped path in the block of resin. A wedging unit wedges the insulating reinforcing piece in position to prevent the insulating reinforcing piece from protruding axially internally on the internal wall with respect to the region so as to leave a determined annular sector of the internal wall in direct adhering contact with the block of resin. |
| US08772987B2 |
Synthetic jet ejector and design thereof to facilitate mass production
A method is provided for making a synthetic jet ejector. The method comprises (a) providing first and second voice coil bodies (131) having first and second sets of channels defined therein, respectively; (b) inserting first and second sets of electrically conductive terminals (139) into the first and second sets of channels, respectively; (c) wrapping first and second coils of wire (151) around said first and second voice coil bodies, respectively, such that the first coil is in electrical contact with the first set of terminals and such that the second coil is in electrical contact with the second set of terminals; (d) forming a voice coil subassembly by attaching first and second ends of a flexible, electrically conductive connector (161) to said first and second voice coil bodies, respectively, wherein the first end of the connector is attached such that it is in electrical contact with the first set of terminals, and wherein the second end of the connector is attached such that it is in electrical contact with the second set of terminals; and (e) incorporating the voice coil subassembly into a synthetic jet ejector (103) having first and second voice coils such that said first coil forms a portion of said first voice coil, and such that said second coil forms a portion of said second voice coil. |
| US08772982B2 |
Multi-gang capacitive touch switch plate
An apparatus is provided and includes two or more sensor assemblies, each including a sensing unit at a front face thereof, and each being communicatively interconnected and power sharing, a cover plate, mounted adjacent to the front face of the sensor assemblies to entirely cover the sensing units, through which user commands are transmittable, and a wall box, onto which the sensor assemblies and the cover plate are mountable, including a housing in which a space is defined for housing of one or more devices, each device being controllable by the sensor assemblies in accordance with the user commands, and each device being disposed to fit within the space and to be in signal communication with at least one of the sensor assemblies. |
| US08772978B2 |
Power transmitting apparatus, power receiving apparatus, and wireless power transmission system
A power transmitting apparatus includes a power transmitting apparatus side passive electrode and a power transmitting apparatus side active electrode, and a power receiving apparatus includes a power receiving apparatus side active electrode and a power receiving apparatus side active electrode. The power transmitting apparatus side active electrode and the power transmitting apparatus side passive electrode are not parallel with each other in terms of a positional relationship, and the power receiving apparatus side active electrode and the power receiving apparatus side passive electrode are not parallel with each other in terms of a positional relationship. By mounting the power receiving apparatus on the power transmitting apparatus, the power transmitting apparatus side passive electrode and active electrode respectively face the power receiving apparatus side passive electrode and active electrode. |
| US08772971B2 |
Wireless energy transfer across variable distances with high-Q capacitively-loaded conducting-wire loops
Described herein are embodiments of at least one source resonator coupled to an energy source generating an oscillating near field region, and at least one device resonator optionally coupled to an electronic device located at a variable distance within the at least one source resonator's near-field region, where at least two of the resonators comprise high-Q capacitively-loaded conducting-wire loops. |
| US08772970B2 |
Lock arrangement and a method of providing power to a lock
A lock arrangement including an electrically powered lock actuator, a power receiver (30) and a power transmitter (18). The electrically powered lock actuator is adapted for mounting in or on a door (10). The power receiver (30) is adapted for mounting in or on the door (10) in electrical connection with the lock actuator. The power transmitter (18) is adapted for mounting adjacent the door (10) and for transmitting power across an air gap to the power receiver (30). |
| US08772968B2 |
Switching configuration and procedure for the production of one alternating voltage from a majority of unrelated supply terminals with temporally variable output DC voltage
A circuit, having a plurality of regulated, parallel, voltage sources, an a.c.-d.c. converter circuit and a regulating unit, and a method for controlling it. The regulated voltage sources include an unregulated voltage source of a temporally variable output d.c. voltage, a step-up converter and an associated regulating device, where the step-up converter is a three-point step-up converter. The regulating unit measures the intermediate circuit voltage of the a.c.-d.c. converter circuit and is connected with the regulating devices. In the method for control, the regulating unit determines the voltage in the intermediate circuit of the a.c.-d.c. converter circuit and from this determines, as a function of the maximally and minimally permissible intermediate circuit voltage, a set-point value for the output voltage of the regulated voltage sources. This set-point value is transmitted to the regulating devices, from which the regulating devices determine the control conditions for the step-up converter. |
| US08772962B2 |
Powered distribution systems for powered rail vehicles
A power distribution system for a rail vehicle includes a propulsion alternator, a first bus, a Head End Power (HEP) alternator, and a second bus. The propulsion alternator is joined to an engine of the rail vehicle. The first bus is joined with the propulsion alternator and is configured to electrically couple the propulsion alternator with a propulsion electric load that propels the rail vehicle. The HEP alternator is joined to the engine. The second bus is joined with the HEP alternator and is adapted to electrically couple the HEP alternator with a non-propulsion electric load of the rail vehicle. The propulsion alternator generates a first electric current to power the propulsion electric load and the HEP alternator separately generates second electric current to power the non-propulsion electric load. The HEP alternator and the second bus are electrically separate from the propulsion alternator and the first bus. |
| US08772961B2 |
Communication device, communication system, and vehicle
A communication device includes: an oscillating circuit for generating a single including a signal potential that is based on a reference potential; a first terminal for communicating with a vehicle; and a first resistance circuit connected between an output of the oscillating circuit and the first terminal and having a resistance value variable according to a first input signal. Preferably, the vehicle includes: a second terminal connected to the first terminal; and a second resistance circuit connected between a ground node fed with the reference potential and the second terminal. The vehicle is provided with a first signal extraction node on a path connecting the second terminal and the second resistance circuit to each other. |
| US08772953B2 |
Semiconductor device and programming method
The present invention include a semiconductor device and a method therefor, the method includes disposing a sheet-shaped resin at a side opposite to the chip mounting portion mounting semiconductor chips to be mounted on the chip mounting portion, and forming a resin sealing portion between the sheet-shaped resin and the chip mounting portion, to seal the semiconductor chips. According to an aspect of the present invention, it is possible to provide a semiconductor device and a fabrication method therefor, by which it is possible to reduce the size of the package and to prevent the generation of an unfilled portion in a resin sealing portion or a filler-removed portion or to prevent the exposure of wire from the resin sealing portion. |
| US08772952B2 |
Semiconductor device with copper wire having different width portions
To improve reliability of a semiconductor device in which wire bonding using a wire made of copper is performed. A semiconductor device is configured so that one of end parts (wide width part) of a copper wire is joined via a bump on a pad (electrode pad) formed over a main surface (first main surface) of a semiconductor chip of the semiconductor device. The bump is made of gold, which is a metal material having a hardness lower than that of copper, and the width of the bump is narrower than the width of the wide width part of the wire. |
| US08772950B2 |
Methods and apparatus for flip chip substrate with guard rings outside of a die attach region
Methods and apparatus for flip chip substrates with guard rings. An embodiment comprises a substrate core with a die attach region for attaching an integrated circuit die; at least one dielectric layer overlying a die side surface of the substrate core; and at least one guard ring formed adjacent a corner of the substrate core, the at least one guard ring comprising: a first trace overlying the dielectric layer having rectangular portions extending in two directions from the corner of the substrate core and in parallel to the edges of the substrate core; a second trace underlying the dielectric layer; and at least one via extending through the dielectric layer and coupling the first and second traces; wherein the first trace, the at least one via, and the second trace form a vertical via stack. Methods for forming the flip chip substrates with the guard rings are disclosed. |
| US08772948B2 |
Method for manufacturing a layer arrangement, and a layer arrangement
A method for manufacturing a layer arrangement in accordance with various embodiments may include: providing a first layer having a side; forming one or more nanoholes in the first layer that are open towards the side of the first layer; depositing a second layer over the side of the first layer. |
| US08772947B2 |
Methods for packaging microelectronic devices and microelectronic devices formed using such methods
Methods for packaging microelectronic devices and microelectronic devices formed using such methods are disclosed herein. One aspect of the invention is directed toward a method for packaging a microelectronic device that includes coupling an active side of a microelectronic die to a surface of a support member. The microelectronic die can have a backside opposite the active side, a peripheral side extending at least part way between the active side and the backside, and at least one through-wafer interconnect. The method can further include applying an encapsulant to cover a portion of the surface of the support member so that a portion of the encapsulant is laterally adjacent to the peripheral side, removing material from a backside of the microelectronic die to expose a portion of at least one through-wafer interconnect, and applying a redistribution structure to the backside of the microelectronic die. |
| US08772940B2 |
Semiconductor device
In a semiconductor device, a first contact-diffusion-layer is in a first well to be connected to the first well and extends in a channel width direction of a first transistor in a first well. A second contact-diffusion-layer is in the first well so as to be electrically connected to the first well and extends in a channel-length direction of the first transistor. A first contact on the first contact-diffusion-layer has a shape with a diameter in the channel-width direction larger than that in the channel-length direction when viewed from above the substrate. A second contact on the second contact-diffusion-layer has a shape with a diameter in the channel-width direction smaller than that of the first contact and a diameter in the channel-length direction almost equal to that of the first contact when viewed from above the substrate. A wiring is electrically connected to the first transistor through the second contact. |
| US08772938B2 |
Semiconductor interconnect structures
Techniques are disclosed that enable improved shorting margin between unlanded conductive interconnect features and neighboring conductive features. In some embodiments, an etch may be applied to an insulator layer having one or more conductive features therein, such that the insulator layer is recessed below the top of the conductive features and the edges of the conductive features are rounded or otherwise softened. A conformal etch stop layer may then be deposited over the conductive features and the insulator material. A second insulator layer may be deposited above the conformal etch stop layer, and an interconnect feature may pass through the second insulator layer and the conformal etch stop layer to connect with the rounded portion of one of the conductive features. In some embodiments, the interconnect feature is an unlanded via and the unlanded portion of the via may or may not penetrate through the conformal barrier layer. |
| US08772937B2 |
Semiconductor device including inner interconnection structure able to conduct signals or voltages in the semiconductor chip with vertical connection vias and horizontal buried conductive lines
A semiconductor device includes a semiconductor chip and an inner interconnection structure. The semiconductor chip includes a front surface that exposes first connection terminals and a rear surface that is opposite to the front surface and exposes second connection terminals separated from the first connection terminals. The inner interconnection structure includes horizontal buried conductive lines and vertical connection lines disposed to pierce the semiconductor chip to connect the first connection terminals and the second connection terminals. |
| US08772936B2 |
Semiconductor device with a copper line and method for manufacturing the same
A semiconductor device with a copper line comprises a lower portion of a copper pattern buried in an interlayer insulating film, an upper portion of the copper disposed over the upper portion of the lower copper pattern, and an upper barrier metal layer disposed over upper and side surfaces of the upper copper pattern. As a result, the copper pattern is protected by the barrier metal layers, providing a metal line with a stable structure. |
| US08772934B2 |
Aluminum interconnection apparatus
An aluminum interconnection apparatus comprises a metal structure formed over a substrate, wherein the metal structure is formed of a copper and aluminum alloy, a first alloy layer formed underneath the metal structure and a first barrier layer formed underneath the first alloy layer, wherein the first barrier layer is generated by a reaction between the first alloy layer and an adjacent dielectric layer during a thermal process. |
| US08772931B2 |
Dual-function integrated circuit
An electronic circuit in a package, including two functions, the package orientation activating a single one of the two functions. |
| US08772929B2 |
Package for three dimensional integrated circuit
A wafer level package includes a semiconductor die bonded on a supporting wafer. The semiconductor die has at least a step recess at its substrate. An underfill layer is formed between the semiconductor die and the supporting wafer. Moreover, the height of the underfill layer is limited by the step recess. During a fabrication process of the wafer level package, the step recess helps to reduce the stress on the wafer level package. |
| US08772927B2 |
Semiconductor package structures having liquid cooler integrated with first level chip package modules
Semiconductor package structures are provided which are designed to have liquid coolers integrally packaged with first level chip modules. In particular, apparatus for integrally packaging a liquid cooler device within a first level chip package structure include structures in which a liquid cooler device is thermally coupled directly to the back side of an integrated circuit chip flip-chip mounted on flexible chip carrier substrate. The liquid cooler device is mechanically coupled to the package substrate through a metallic stiffener structure that is bonded to the flexible package substrate to provide mechanical rigidity to the flexible package substrate. |
| US08772909B1 |
Isolator with integral transformer
A signal isolator comprises a multilayer substrate with conductive layers separated by insulation. A region within the substrate is defined by upper and lower conductive shields. A transformer, including primary and secondary windings, is formed in the region. Circuitry supported on an upper conductive layer includes a high frequency oscillator for receiving an input signal, the high frequency oscillator being connected to excite the primary winding in response to the signal. A detector circuit coupled to the secondary winding is adapted to provide an output signal in response to the high frequency oscillator excitation of the primary winding. The circuitry may be powered exclusively by power received from the input signal. The oscillator may modulate the primary excitation and the detector may vary the magnitude of the output in response to the modulation. A plurality of isolator channels may be provided on a single multilayer substrate. |
| US08772902B2 |
Fabrication of a localized thick box with planar oxide/SOI interface on bulk silicon substrate for silicon photonics integration
Line trenches are formed in a stack of a bulk semiconductor substrate and an oxygen-impermeable layer such that the depth of the trenches in the bulk semiconductor substrate is greater than the lateral spacing between a pair of adjacently located line trenches. Oxygen-impermeable spacers are formed on sidewalls of the line trenches. An isotropic etch, either alone or in combination with oxidation, removes a semiconductor material from below the oxygen-impermeable spacers to expand the lateral extent of expanded-bottom portions of the line trenches, and to reduce the lateral spacing between adjacent expanded-bottom portions. The semiconductor material around the bottom portions is oxidized to form a semiconductor oxide portion that underlies multiple oxygen-impermeable spacers. Semiconductor-on-insulator (SOI) portions are formed above the semiconductor oxide portion and within the bulk semiconductor substrate. |
| US08772901B2 |
Termination structure for gallium nitride schottky diode
A termination structure for a nitride-based Schottky diode includes a guard ring formed by an epitaxially grown P-type nitride-based compound semiconductor layer and dielectric field plates formed on the guard ring. The termination structure is formed at the edge of the anode electrode of the Schottky diode and has the effect of reducing electric field crowding at the anode electrode edge, especially when the Schottky diode is reverse biased. In one embodiment, the P-type epitaxial layer includes a step recess to further enhance the field spreading effect of the termination structure. |
| US08772900B2 |
Trench Schottky barrier diode and manufacturing method thereof
The present invention discloses a trench Schottky barrier diode (SBD) and a manufacturing method thereof. The trench SBD includes: an epitaxial layer, formed on a substrate; multiple mesas, defined by multiple trenches; a field plate, formed on the epitaxial layer and filled in the multiple trenches, wherein a Schottky contact is formed between the field plate and top surfaces of the mesas; a termination region, formed outside the multiple mesas and electrically connected to the field plate; a field isolation layer, formed on the upper surface and located outside the termination region; and at least one mitigation electrode, formed below the upper surface outside the termination region, and is electrically connected to the field plate through the field isolation layer, wherein the mitigation electrode and the termination region are separated by part of a dielectric layer and part of the epitaxial layer. |
| US08772896B2 |
Semiconductor photodetector that causes avalanche multiplication to occur only at photodetector portion located at central portion of mesa structure
In order to improve reliability by preventing an edge breakdown in a semiconductor photodetector having a mesa structure such as a mesa APD, the semiconductor photodetector includes a mesa structure formed on a first semiconductor layer of the first conduction type formed on a semiconductor substrate, the mesa structure including a light absorbing layer for absorbing light, an electric field buffer layer for dropping an electric field intensity, an avalanche multiplication layer for causing avalanche multiplication to occur, and a second semiconductor layer of the second conduction type, wherein the thickness of the avalanche multiplication layer at the portion in the vicinity of the side face of the mesa structure is made thinner than the thickness at the central portion of the mesa structure. |
| US08772894B2 |
Trench process and structure for backside contact solar cells with polysilicon doped regions
A solar cell includes polysilicon P-type and N-type doped regions on a backside of a substrate, such as a silicon wafer. A trench structure separates the P-type doped region from the N-type doped region. Each of the P-type and N-type doped regions may be formed over a thin dielectric layer. The trench structure may include a textured surface for increased solar radiation collection. Among other advantages, the resulting structure increases efficiency by providing isolation between adjacent P-type and N-type doped regions, thereby preventing recombination in a space charge region where the doped regions would have touched. |
| US08772891B2 |
Lateral overflow drain and channel stop regions in image sensors
A lateral overflow drain and a channel stop are fabricated using a double mask process. Each lateral overflow drain is formed within a respective channel stop. Due to the use of two mask layers, one edge of each lateral overflow drain is aligned, or substantially aligned, with an edge of a respective channel stop. |
| US08772885B2 |
MEMS sensing device and method for the same
The present invention discloses a MEMS sensing device which comprises a substrate, a MEMS device region, a film, an adhesive layer, a cover, at least one opening, and a plurality of leads. The substrate has a first surface and a second surface opposite the first surface. The MEMS device region is on the first surface, and includes a chamber. The film is overlaid on the MEMS device region to seal the chamber as a sealed space. The cover is mounted on the MEMS device region and adhered by the adhesive layer. The opening is on the cover or the adhesive layer, allowing the pressure of the air outside the device to pressure the film. The leads are electrically connected to the MEMS device region, and extend to the second surface. |
| US08772880B2 |
Semiconductor integrated circuit device
A high-speed semiconductor integrated circuit device is achieved by adjusting an offset voltage. For example, dummy NMOS transistors MND1 (MND1a and MND1b) and MND2 (MND2a and MND2b) are connected to drain outputs of NMOS transistors MN1 and MN2 operated according to differential input signals Din_p and Din_n, respectively. The MND1 is arranged adjacent to the MN1, and a source of the MND1a and a drain of the MN1 share a diffusion layer. The MND2 is arranged adjacent to the MN2, and a source of the MND2a and a drain of the MN2 share a diffusion layer. The MND1 and the MND2 function as dummy transistors for suppressing variations in process of the MN1 and the MN2 and, and besides, they also function as means for adjusting the offset voltage by appropriately applying an offset-amount setting signal OFST to each gate to provide a capacitor to either the MN1 or the MN2. |
| US08772879B2 |
Electronic component comprising a number of MOSFET transistors and manufacturing method
An electronic component including a number of insulated-gate field effect transistors, said transistors belonging to at least two distinct subsets by virtue of their threshold voltage, wherein each transistor includes a gate that has two electrodes, namely a first electrode embedded inside the substrate where the channel of the transistor is defined and a second upper electrode located above the substrate facing buried electrode relative to channel and separated from said channel by a layer of dielectric material and wherein the embedded electrodes of all the transistors are formed by an identical material, the upper electrodes having a layer that is in contact with the dielectric material which is formed by materials that differ from one subset of transistors to another. |
| US08772877B2 |
Tunnel field-effect transistor
A tunnel field-effect transistor including at least: a source region including a corresponding source semiconductor material; a drain region including a corresponding drain semiconductor material, and a channel region including a corresponding channel semiconductor material, which is arranged between the source region and the drain region. The tunnel field-effect transistor further includes at least: a source-channel gate electrode provided on an interface between the source region and the channel region; an insulator corresponding to the source-channel gate electrode that is provided between the source-channel gate electrode and the interface between the source region and the channel region; a drain-channel gate electrode provided on an interface between the drain region and the channel region; and an insulator corresponding to the drain-channel gate electrode that is provided between the drain-channel gate electrode and the interface between the drain region and the channel region. |
| US08772873B2 |
Ge-on-insulator structure and method for forming the same
A method for forming a Ge-on-insulator structure is provided, comprising steps of: forming a Ge layer (1200) on a substrate (2000); treating a first surface of the Ge layer (1200) to form a first semiconducting metal-germanide passivation layer (1300); bonding the first semiconducting metal-germanide passivation layer (1300) with a silicon substrate (1100), wherein on a surface of the silicon substrate (1100) an oxide insulating layer is formed; and removing the substrate (2000). Further, a Ge-on-insulator structure formed by the method is also provided. |
| US08772867B2 |
High voltage high side DMOS and the method for forming thereof
A high voltage high side DMOS removing the N-buried layer from the DMOS bottom provides lower Ron*A at given breakdown voltage. The high voltage high side DMOS has a P-type substrate, an epitaxial layer, a field oxide, an N-type well region a gate oxide, a gate poly, a P-type base region, a deep P-type region, an N-type lightly doped well region, a first N-type highly doped region, a second N-type highly doped region and a P-type highly doped region. |
| US08772866B2 |
Semiconductor device and method for fabricating the same
A semiconductor device comprises a buried gate formed by being buried under a surface of a semiconductor substrate, a dummy gate formed on the buried gate, and a landing plug formed on a junction region of the semiconductor substrate being adjacent to the dummy gate. |
| US08772865B2 |
MOS transistor structure
In one embodiment, an MOS transistor is formed to have an active region and a termination region. Within the termination region a plurality of conductors are formed to make electrical contact to conductors that are within a plurality of trenches. The plurality of conductors in the termination region are formed to be substantially coplanar. |
| US08772860B2 |
FINFET transistor structure and method for making the same
A FINFET transistor structure includes a substrate, a fin structure, an insulating layer and a gate structure. The fin structure is disposed on the substrate and directly connected to the substrate. Besides, the fin structure includes a fin conductive layer and a bottle neck. The insulating layer covers the substrate and has a protruding side which is formed by partially surrounding the bottle neck of the fin structure, and a bottom side in direct contact with the substrate so that the protruding side extend to and under the fin structure. The gate structure partially surrounds the fin structure. |
| US08772858B2 |
Vertical channel memory and manufacturing method thereof and operating method using the same
A vertical channel memory including a substrate, a channel, a multi-layer structure, a gate, a first terminal and a second terminal is provided. The channel protrudes from the substrate and has a top surface and two vertical surfaces. The multi-layer structure is disposed on the two vertical surfaces of the channel. The gate straddling multi-layer structure is positioned above the two vertical surfaces of the channel. The first terminal and the second terminal are respectively positioned at two sides of the channel opposing to the gate. |
| US08772848B2 |
Circuit structures, memory circuitry, and methods
A circuit structure includes a substrate having an array region and a peripheral region. The substrate in the array and peripheral regions includes insulator material over first semiconductor material, conductive material over the insulator material, and second semiconductor material over the conductive material. The array region includes vertical circuit devices which include the second semiconductor material. The peripheral region includes horizontal circuit devices which include the second semiconductor material. The horizontal circuit devices in the peripheral region individually have a floating body which includes the second semiconductor material. The conductive material in the peripheral region is under and electrically coupled to the second semiconductor material of the floating bodies. Conductive straps in the array region are under the vertical circuit devices. The conductive straps include the conductive material and individually are electrically coupled to a plurality of the vertical circuit devices in the array region. Other implementations are disclosed. |
| US08772847B2 |
Semiconductor device and method for producing the same
A semiconductor device includes a semiconductor substrate; a first insulating film that is formed over the semiconductor substrate; a capacitor that is formed over the first insulating film and is formed by sequentially stacking a lower electrode, a capacitor dielectric film, and an upper electrode; a second insulating film that is formed over the capacitor and has a hole including the entire region of the upper electrode in plan view; and a conductor plug that is formed in the hole and contains tungsten. |
| US08772841B2 |
Reactive metal implated oxide based memory
Methods, devices, and systems associated with oxide based memory can include a method of forming an oxide based memory cell. Forming an oxide based memory cell can include forming a first conductive element, forming an oxide over the first conductive element, implanting a reactive metal into the oxide, and forming a second conductive element over the oxide. |
| US08772840B2 |
Memory device comprising an array portion and a logic portion
In an embodiment of the present invention, a method comprises patterning a first plurality of semiconductor structures in an array portion of a semiconductor substrate using a first photolithographic mask. The method further comprises patterning a second plurality of semiconductor structures over a logic portion of a semiconductor substrate using a second photolithographic mask. The method further comprises patterning a sacrificial layer over the first plurality of semiconductor structures using the second photolithographic mask. The sacrificial layer is patterned simultaneously with the second plurality of semiconductor structures. |
| US08772836B2 |
Semiconductor device
To provide a semiconductor device in which a rectifying element capable of reducing a leak current in reverse bias when a high voltage is applied and reducing a forward voltage drop Vf and a transistor element are integrally formed on a single substrate.A semiconductor device has a transistor element and a rectifying element on a single substrate. The transistor element has an active layer formed on the substrate and three electrodes (source electrode, drain electrode, and gate electrode) disposed on the active layer. The rectifying element has an anode electrode disposed on the active layer, a cathode electrode which is the drain electrode, and a first auxiliary electrode between the anode electrode and cathode electrode. |
| US08772832B2 |
GaN HEMTs with a back gate connected to the source
The present invention reduces the dynamic on resistance in the channel layer of a GaN device by etching a void in the nucleation and buffer layers between the gate and the drain. This void and the underside of the device substrate may be plated to form a back gate metal layer. The present invention increases the device breakdown voltage by reducing the electric field strength from the gate to the drain of a HEMT. This electric field strength is reduced by placing a back gate metal layer below the active region of the channel. The back gate metal layer may be in electrical contact with the source or drain. |
| US08772830B2 |
Semiconductor wafer including lattice matched or pseudo-lattice matched buffer and GE layers, and electronic device
A high-quality GaAs-type crystal thin film using an inexpensive Si wafer with good thermal release characteristics is achieved. Provided is a semiconductor wafer comprising an Si wafer; an inhibiting layer that is formed on the wafer and that inhibits crystal growth, the inhibiting layer including a covering region that covers a portion of the wafer and an open region that does not cover a portion of the wafer within the covering region; a Ge layer that is crystal-grown in the open region; a buffer layer that is crystal-grown on the Ge layer and is a group 3-5 compound semiconductor layer containing P; and a functional layer that is crystal-grown on the buffer layer. The Ge layer may be formed then annealing with a temperature and duration that enables movement of crystal defects. |
| US08772828B2 |
Trench poly ESD formation for trench MOS and SGT
A semiconductor device includes a semiconductor material disposed in a trench with polysilicon lining at least the bottom of the trench. The semiconductor material includes differently doped regions configured as a PNP or NPN structure formed in the trench with differently doped regions located side by side across a width of the trench. It is emphasized that this abstract is provided to comply with rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. |
| US08772826B2 |
Photoelectric conversion device
It is an object to provide a photoelectric conversion device with high photoelectric conversion efficiency. The photoelectric conversion device includes an electrode layer, and a light absorbing layer located on the electrode layer. The light absorbing layer is comprised of a plurality of stacked semiconductor layers containing a chalcopyrite-based compound semiconductor. The semiconductor layers contain oxygen. A molar concentration of the oxygen in surfaces and their vicinities of the semiconductor layers where the semiconductor layers are stacked on each other is higher than average molar concentrations of the oxygen in the semiconductor layers. |
| US08772824B2 |
Organic light-emitting display system and method of manufacturing the same
An organic light-emitting display system and a method of manufacturing the same are disclosed. In one aspect, the organic light-emitting display system includes a substrate, a display unit that defines an active area on the substrate and includes a plurality of thin film transistor (TFTs), and an encapsulation layer that seals the display unit and has a stacked structure in which at least a first inorganic film, a first organic film, and a second inorganic film are sequentially stacked. The TFTs includes an active layer, a gate electrode, a source electrode, a drain electrode, and an interlayer insulating film that is disposed between the gate electrode and the source electrode and between the gate electrode and the drain electrode, wherein the second inorganic film directly contacts the interlayer insulating film outside the active area. Accordingly, in various embodiments, since an inorganic layer of a thin film encapsulation layer is prevented from being cracked, penetration of external moisture or oxygen into the active area of the display can be reduced or prevents. |
| US08772818B2 |
Radiation-emitting device and method for producing a radiation-emitting device
A radiation-emitting device is provided which comprises a substrate (10), at least one organic functional layer (100) on the substrate (10) and a second electrode (80) on the at least one organic functional layer (100). The substrate (10) includes a plastics film (1) and a metal film (3), and the metal film (3) is arranged between the plastics film (1) and the at least one organic functional layer (100) and is set up as a first electrode. A method is additionally provided for producing such a device. |
| US08772817B2 |
Electronic device submounts including substrates with thermally conductive vias
A submount for an electronic device includes a substrate formed of a bulk material including first and second major surfaces on opposite sides of the substrate, a surface insulating layer on the first major surface of the substrate, and a die attach pad on the surface insulating layer. The die attach pad may be electrically insulated from the substrate by the surface insulating layer. The submount further includes a heatsink contact pad on the second major surface of the substrate, and a thermal conduction member extending from the second major surface of the conductive semiconductor substrate through the substrate toward the first major surface of the substrate. The thermal conduction member has a higher thermal conductivity than a thermal conductivity of the bulk material of the substrate. |
| US08772812B2 |
Curable organopolysiloxane composition and optical semiconductor device
A curable organopolysiloxane composition can be used as a sealant or a bonding agent for optical semiconductor elements. The composition comprises at least the following components: (A) a multi-constituent, alkenyl-containing organopolysiloxane; (B) an organopolysiloxane that contains silicon-bonded hydrogen atoms and comprises constituent (B-1) containing at least 0.5 wt. % of silicon-bonded hydrogen atoms and constituent (B-2) containing at least 0.5 wt. % of silicon-bonded hydrogen atoms, and, if necessary, constituent (B-3), an organopolysiloxane; and (C) a hydrosilylation-reaction catalyst. The composition can form a cured body that possesses long-lasting properties of light transmittance and bondability, and relatively high hardness. |
| US08772811B2 |
Light emitting diode
A light emitting diode and a light emitting diode (LED) manufacturing method are disclosed. The LED comprises a substrate; a first n-type GaN layer; a second n-type GaN layer; an active layer; and a p-type GaN layer formed on the substrate in sequence; the second n-type GaN layers has a bottom surface interfacing with the first n-type GaN layer, a rim of the bottom surface has a roughened exposed portion, and Ga—N bonds on the bottom surface has an N-face polarity. |
| US08772805B2 |
High efficiency light emitting diode and method for fabricating the same
A high-efficiency light emitting diode including: a semiconductor stack positioned on a support substrate, including a p-type compound semiconductor layer, an active layer, and an n-type compound semiconductor layer; an insulating layer disposed in an opening that divides the p-type compound semiconductor layer and active layer; a transparent electrode layer disposed on the insulating layer and the p-type compound semiconductor layer; a reflective insulating layer covering the transparent electrode layer, to reflect light from the active layer away from the support substrate; a p-electrode covering the reflective insulating layer; and an n-electrode is formed on top of the n-type compound semiconductor layer. The p-electrode is electrically connected to the transparent electrode layer through the insulating layer. |
| US08772796B2 |
Panel and method for fabricating the same
A panel is disclosed, in which, a patterned semiconductor layer is formed on an insulation layer. The patterned semiconductor layer includes a portion corresponding to an electrode and another portion corresponding to a wiring trace. The portion corresponding to the electrode may be formed as, for example, a channel, and the other portion corresponding to the wiring trace may protect the wiring trace during fabrication process or in the structure from scratching or corrosion. |
| US08772793B2 |
Light emitting diodes and method for manufacturing the same
An exemplary LED includes an electrode layer, an LED die, a transparent electrically conductive layer, and an electrically insulating layer. The electrode layer includes a first section and a second section electrically insulated from the first section. The LED die is arranged on and electrically connected to the second section of the electrode layer. The transparent electrically conductive layer is formed on the LED die and electrically connects the LED die to the first section of the electrode layer. The electrically insulating layer is located between the LED die and the transparent electrically conductive layer to insulate the transparent electrically conductive layer from the second section of the electrode layer. |
| US08772792B2 |
LED with surface roughening
An LED having a p-type layer of material with an associated p-contact, an n-type layer of material with an associated n-contact and an active region between the p-type layer and the n-type layer, includes a roughened emitting-side surface to further enhance light extraction. |
| US08772791B2 |
Light-emitting device
Disclosed is a light-emitting device, comprising: a first multi-quantum well structure comprising a plurality of first well layers and a first barrier layer stacked alternately, wherein the energy gap of the first barrier layer is larger than that of any one of the first well layers; a second multi-quantum well structure comprising a plurality of second well layers and a second barrier layer stacked alternately, wherein the energy gap of the second barrier layer is larger than that of any one of the second well layers; and a third barrier layer disposed between the first multi-quantum well structure and the second multi-quantum well structure, and the third barrier layer connected with the first well layer and the second well layer, wherein the energy gap of the third barrier layer is larger than that of any one of the first well layers and the second well layers, and the thickness of the third barrier layer is larger than that of any one of the first barrier layer and the second barrier layer. |
| US08772784B2 |
Semiconductor device including pair of electrodes and oxide semiconductor film with films of low conductivity therebetween
One of factors that increase the contact resistance at the interface between a first semiconductor layer where a channel is formed and source and drain electrode layers is a film with high electric resistance formed by dust or impurity contamination of a surface of a metal material serving as the source and drain electrode layers. As a solution, a first protective layer and a second protective layer including a second semiconductor having a conductivity that is less than or equal to that of the first semiconductor layer is stacked successively over source and drain electrode layers without exposed to air, the stack of films is used for the source and drain electrode layers. |
| US08772778B2 |
Semiconductor device and manufacturing method thereof
A high reliability semiconductor display device is provided. A semiconductor layer in the semiconductor display device has a channel forming region, an LDD region, a source region, and a drain region, and the LDD region overlaps a first gate electrode, sandwiching a gate insulating film. |
| US08772774B2 |
Backplane structures for organic light emitting electronic devices using a TFT substrate
There is provided a backplane for an organic electronic device including a TFT substrate having a base substrate, a polysilicon layer, a gate dielectric layer, a gate electrode, an interlayer dielectric, and a data electrode; an insulating layer over the TFT substrate; a multiplicity of first openings in the insulating layer having a depth d1; a multiplicity of pixelated diode electrode structures, wherein a first set of diode electrode structures are in the first openings; and a bank structure defining pixel areas over the diode electrode structures; wherein the first openings and first set of diode electrode structures are in at least a first set of the pixel areas. |
| US08772771B2 |
Method for manufacturing semiconductor device
Miniaturized transistors having high and stable electric characteristics using high precision microfabrication are provided with high yield. Further, high performance, high reliability, and high productivity also of a semiconductor device including the transistor are achieved. A semiconductor device includes a vertical transistor in which a first electrode layer, a first oxide film containing indium, gallium, zinc, and nitrogen as main components, an oxide semiconductor film containing indium, gallium, and zinc as main components, a second oxide film containing indium, gallium, zinc, and nitrogen as main components, and a second electrode layer are stacked in this order, and a first gate insulating film and a first gate electrode layer are provided at one side of the columnar oxide semiconductor film and a second gate insulating film and a second gate electrode layer are provided at the other side of the columnar oxide semiconductor film. |
| US08772767B2 |
Organic light-emitting diode luminaires
There is provided an organic light-emitting diode luminaire. The luminaire includes a patterned first electrode, a second electrode, and a light-emitting layer therebetween. The light-emitting layer includes a first plurality of pixels having an emission color that is blue; a second plurality of pixels having an emission color that is green, the second plurality of pixels being laterally spaced from the first plurality of pixels; and a third plurality of pixels having an emission color that is red-orange, the third plurality of pixels being laterally spaced from the first and second pluralities of pixels. The additive mixing of all the emitted colors results in an overall emission of white light. |
| US08772765B2 |
Electroluminescent organic transistor
An electroluminescent organic transistor is described. The electroluminescent organic transistor has a semiconductor heterostructure constituted by a plurality of layers of semiconductor materials of p-type and n-type, which act, respectively, for the conduction of holes and electrons within the heterostructure, and at least two layers of emitting materials each of which is interposed between, and in direct contact with, one of the layers of p-type semiconductor material and another one of the layers of n-type semiconductor material. |
| US08772763B2 |
Photovoltaic cell
The present invention provides a photovoltaic cell having a large short-circuit current density and a large photoelectric conversion efficiency.This photovoltaic cell comprises: a first electrode; a second electrode; an active layer between the first electrode and the second electrode; wherein the active layer contains a macromolecular compound having a structural unit represented by Formula (1): wherein Ar1 and Ar2 are the same as or different from each other and represent a trivalent aromatic hydrocarbon group or a trivalent heterocyclic group; X1 and X2 are the same as or different from each other and represent —O—, —S—, —C(═O)—, —S(═O)—, —SO2—, —C(R50)(R51)—, —Si(R3)(R4)—, —N(R5)—, —B(R6)—, —P(R7)—, or —P(═O)(R8)—; R50, R51, R3, R4, R5, R6, R7, and R8 are the same as or different from each other and represent a hydrogen atom, a halogen atom, or a monovalent organic group; and X1 and Ar2 are bonded with atoms adjacent to each other on a ring that constitutes Ar1, and X2 and Ar1 are bonded with atoms adjacent to each other on a ring that constitutes Ar2, wherein an inverse of the excitation energy of the macromolecular compound from a ground singlet state to a lowest excited singlet state that is calculated using the time-dependent density functional theory is 0.43 (eV−1) or more. |
| US08772757B2 |
Deep ultraviolet light emitting devices and methods of fabricating deep ultraviolet light emitting devices
Light emitting devices and methods of fabricating light emitting devices that emit at wavelengths less than 360 nm with wall plug efficiencies of at least than 4% are provided. Wall plug efficiencies may be at least 5% or at least 6%. Light emitting devices and methods of fabricating light emitting devices that emit at wavelengths less than 345 nm with wall plug efficiencies of at least than 2% are also provided. Light emitting devices and methods of fabricating light emitting devices that emit at wavelengths less than 330 nm with wall plug efficiencies of at least than 0.4% are provided. Light emitting devices and methods of fabricating light emitting devices having a peak output wavelength of not greater than 360 nm and an output power of at least 5 mW, having a peak output wavelength of 345 nm or less and an output power of at least 3 mW and/or a peak output wavelength of 330 nm or less and an output power of at least 0.3 mW at a current density of less than about 0.35 μA/μm2 are also provided. The semiconductor light emitting devices may have a direct current lifetime of at least 100 hours, at least 500 hours or at least 1000 hours. |
| US08772752B2 |
Semiconductor device
An object is to prevent light leakage caused due to misregistration even when the width of a black matrix layer is not expanded to a designed value or larger. One embodiment of the present invention is a semiconductor device including a single-gate thin film transistor in which a first semiconductor layer is sandwiched between a bottom-gate electrode and a first black matrix layer. The first semiconductor layer and the first black matrix layer overlap with each other. |
| US08772748B2 |
Semiconductor memory device using variable resistance element or phase-change element as memory device
A semiconductor memory device includes a first conductive line, a second conductive line, a cell unit, a silicon nitride film and a double-sidewall film. The first conductive line extends in a first direction. The second conductive line extends in a second direction crossing the first direction. The cell unit includes a phase-change film and a rectifier element connected in series with each other between the first conductive line and the second conductive line. The silicon nitride film is formed on a side surface of the phase-change film. The double-sidewall film includes a silicon oxide film and the silicon nitride film formed on a side surface of the rectifier element. |
| US08772747B2 |
Composite target sputtering for forming doped phase change materials
A layer of phase change material with silicon or another semiconductor, or a silicon-based or other semiconductor-based additive, is formed using a composite sputter target including the silicon or other semiconductor, and the phase change material. The concentration of silicon or other semiconductor is more than five times greater than the specified concentration of silicon or other semiconductor in the layer being formed. For silicon-based additive in GST-type phase change materials, sputter target may comprise more than 40 at % silicon. Silicon-based or other semiconductor-based additives can be formed using the composite sputter target with a flow of reactive gases, such as oxygen or nitrogen, in the sputter chamber during the deposition. |
| US08772746B2 |
Semiconductor memory device
A semiconductor memory device in which the cell area can be decreased and the minimum feature size is not restricted by the thickness of the material forming the memory cell. In a semiconductor memory device, a gate insulating film, a channel extending in a direction X, and a resistance change element extending in the direction X are formed successively above multiple word lines extending in a direction Y, and a portion of the channel and a portion of the resistance change element are disposed above each of the plurality of the word lines. Such configuration can decrease the cell area and ensure the degree of design freedom. |
| US08772745B1 |
X-ray obscuration film and related techniques
An X-ray obscuration (XRO) film comprising one or more metallic wire mesh layers and an adjacent layer of indium foil having portions which extend into openings of the wire mesh and in contact with metallic portions thereof. The XRO film can be capable of absorbing at least a portion of X-ray energy thereby creating an interference pattern when the XRO film is coupled with an electronic circuit and placed between an X-ray source and an X-ray detector and subjected to radiographic inspection. The interference pattern can create sufficient visual static to effectively obscure circuit lines in the electronic circuit when subjected to radiographic inspection techniques. The XRO film can be substantially thinner than existing solutions for preventing X-ray inspection with an exemplary embodiment being no more than 5 mils thick. The metallic XRO film can also provide electromagnetic shielding and/or heat dissipation for electronic circuits. |
| US08772744B1 |
Air-flow activated germicidal UV-C lights in HVAC system
UV-C light assembly is designed to kill germs (bacteria, molds, protozoa, virus, and yeast) in the forced airstreams of HVAC systems, thus preventing the spreading of germs into other rooms or spaces. An air-flow activated switch is invented for turning on the UV-C lights when airstreams pass through and turning off when airstreams stop in the HVAC systems. The UV-C light assembly is installed inside duct through air filter's opening. The UV-C germicidal assembly is an easy add-on to an existing HVAC system for indoor air purification. The UV-C light sources are either LEDs or fluorescent tubes. |
| US08772743B2 |
Control method for electron beam sterilizing device and device performing said method
An electron beam sterilizing device, comprises: an electron-generating filament; a beam-shaper; an output window; a high-voltage supply, capable of creating a high-voltage potential between the electron-generating filament and the output window, for acceleration of electrons; a high-voltage supply for driving current through the electron-generating filament; a control unit for controlling the operation of the electron beam sterilizing device. The electron beam sterilizing device has at least three operational states which include: an OFF-state, where there is no drive current through the electron-generating filament; an ON-state, where the electron-generating filament is kept at a temperature above the emission temperature so as to generate electrons for sterilization; and a standby state, between the OFF-state and ON-state, where the electron-generating filament is kept at a predetermined temperature just below the emission temperature. The control unit controls the device to assume the standby state. |
| US08772740B2 |
UV curing creating flattop and roundtop structures on a single printing plate
A method of imaging a printing plate and curing the printing plate made of or having photo-curable material that includes an ablatable mask. In one embodiment, the method comprises imaging the ablatable mask with a first portion of imaging data to produce a partially imaged uncured plate. Imaging data includes the first portion and a second portion of imaging data. The method includes curing the partially imaged uncured plate using UV with a first set of parameters to produce a partially cured plate with a partially ablated mask thereon, the curing arranged for producing flat tops, imaging the partially ablated mask on the partially cured plate with the second portion of imaging data to produce a totally imaged partially cured plate, and curing the totally imaged partially cured plate with a second set of one or more curing parameters to produce a totally cured plate to produce round tops. |
| US08772738B2 |
Particle analyzing apparatus and particle imaging method
A particle analyzing apparatus, comprising: a flow cell which forms a specimen flow including particles; first and second light sources; an irradiation optical system which applies lights emitted from the first and second light sources so that the lights are applied to the specimen flow; a detector which detects forward scattered light, the forward scattered light being emitted from the first light and scattered by the particle in the specimen flow, and generates a signal according to the detected scattered light; a light blocking member disposed between the flow cell and the detector; a controller which obtains characteristic parameters of the particle based on the signal from the detector; and an imaging device which captures an image of the particle in the specimen flow using the light from the second light source is disclosed. Particle imaging method is also disclosed. |
| US08772737B2 |
Conductive element for electrically coupling an EUVL mask to a supporting chuck
A coupling module may include an upper portion that defines an aperture, mask contact elements, chuck contact elements and an intermediate element that is connected between the mask contact elements and the upper portion. A shape and a size of the aperture may correspond to a shape and size of a pattern transfer area of an extreme ultra violet (EUVL) mask. The coupling module may be shaped and sized so that once the mask contact elements contact the upper portion of the EUVL mask, the chuck contact elements contact a chuck that supports the mask. The coupling module may further provide at least one conductive path between the upper portion of the EUVL mask and the chuck when the EUVL mask is positioned on the chuck. |
| US08772730B2 |
Photon counting detector to generate high-resolution images and high-contrast images, and photon counting and detecting method using the same
A photon counting detector and a photon counting and detecting method using the same is provided. The photon counting detector includes readout circuits configured to count photons in multi-energy radiation incident to a sensor, the photons being counted with respect to each of a plurality of energy bands of the multi-energy radiation, the readout circuits respectively corresponding to pixels of a region onto which the multi-energy radiation is irradiated, each of the readout circuits being configured to count photons in a predetermined one of the energy bands, at least one of the readout circuits being configured to count photons in at least one of energy bands other than the predetermined one of the energy bands. |
| US08772729B1 |
APDs using nano-plasmonic metamaterials
An avalanche photodiode (APD) electro-magnetic radiation (EMR) detector is described. The detector includes an EMR absorption region, a voltage biasing element, and a charge multiplication region. The EMR absorption region includes a substantially regular array of nano-particles embedded in a matrix material. The voltage biasing element is configured to apply a bias voltage to the matrix material such that electrical current is directly generated in the EMR absorption region based on a cooperative plasmon effect in the detector material when electro-magnetic radiation in a predetermined wavelength range is incident upon the detector material, where the dominant mechanism for decay in the cooperative plasmon effect is non-radiative. The charge multiplication region is arranged relative to the EMR absorption region to avalanche multiply the electrical current generated in the EMR absorption region. |
| US08772726B2 |
Apparatus and method for data acquisition using an imaging apparatus
A detector tile (116) of an imaging detector array (112) includes a scintillator array (202), a photosensor array (204), which includes a plurality of photosensitive pixels, optically coupled to the scintillator array (202), and a current-to-frequency (I/F) converter (302). The I/F converter (302) includes an integrator (304) that integrates charge output by a photosensitive pixel during an integration period and generates a signal indicative thereof and a comparator (310) that generates a pulse when the generated signal satisfies predetermined criteria during the integration period. A reset device (316) resets the integrator (304) in response to the comparator (310) generating a pulse. Circuitry (320, 324) samples the generated signal at a beginning of the integration period and/or at an end of the integration period and generates quantized digital data indicative thereof. Logic (322) estimates the charge at the input of the integrator (304) based on the generated digital data. |
| US08772724B2 |
Low power, inexpensive velocity detection using a PIR array
Methods and systems may include a system including a first passive motion sensor having a lateral field of view with a first edge and a second passive motion sensor having a lateral field of view with a second edge that is substantially parallel to the first edge. The first and second edges can define a virtual beam. The system may also include logic to receive signals from the first and second passive motion sensors and determine a gait velocity and level of activity based on the signals from the first and second passive motion sensors. |
| US08772720B2 |
System and method for monitoring unsaturated zone gas and near-surface atmosphere in real time by using isotope analyzer
Disclosed are a system and a method for monitoring unsaturated zone gas and near-surface atmosphere in real time by using an isotope analyzer. The system includes a near-surface atmosphere analyzer including a fixing member, a plurality of near-surface gas inlets, a plurality of gas transfer members communicating with the near-surface gas inlets, an analyzing member including an isotope analyzer, which analyzes an isotope of gas transferred through the gas transfer members, a channel connected to the gas transfer members and the analyzing member to select one gas transfer member and to supply gas transferred through the selected gas transfer member to the analyzing member, and a connection member connecting the channel to the analyzing member, a communication device transmitting components of the isotope output from the isotope analyzer, and a monitoring server outputting the components of the isotope transmitted from the communication device. |
| US08772717B2 |
Radiation detector having a bandgap engineered absorber
A radiation detector is provided that includes a photodiode having a radiation absorber with a graded multilayer structure. Each layer of the absorber is formed from a semiconductor material, such as HgCdTe. A first of the layers is formed to have a first predetermined wavelength cutoff. A second of the layers is disposed over the first layer and beneath the first surface of the absorber through which radiation is received. The second layer has a graded composition structure of the semiconductor material such that the wavelength cutoff of the second layer varies from a second predetermined wavelength cutoff to the first predetermined wavelength cutoff such that the second layer has a progressively smaller bandgap than the first bandgap of the first layer. The graded multilayer radiation absorber structure enables carriers to flow toward a conductor that is used for measuring the radiation being sensed by the radiation absorber. |
| US08772716B2 |
Phase plate for a TEM
A phase plate, specifically a Zernike type phase plate, for use in an electron microscope comprises a central hole, and a thin film causing a phase shift of the electrons passing through said film. This phase shift causes the Contrast Transfer Function (CTF) to change from a sine-like function to a cosine-like function.The phase plate is equipped with a film in the form of an annulus, carried by a much thinner film. As a result only in a small spatial frequency range (for low frequencies) the phase is changed (and thus the CTF), and for other spatial frequencies the phase shift is negligible, and thus the CTF remains unchanged. Due to the much smaller thickness of the carrier film the scattering of electrons is negligible as well. |
| US08772709B2 |
Assembly for an electrospray ion source
An assembly for use in an electrospray ion source includes a capillary for guiding a flow of liquid generally containing analyte(s) of interest, which is to be electrosprayed into an ionization chamber, a first tube at least partially encasing the capillary such that a first conduit for guiding a first heatable gas is created proximate the capillary and a hollow member that has an internal evacuated space and is located at the outer circumference of the capillary such that heat transfer from the first heatable gas flowing proximate the capillary to the liquid in the capillary is impeded. The assembly provides a simple and lean/compact way of preventing excessive heat transfer to the liquid in the capillary of an electrospray ion source. |
| US08772706B2 |
Multiple wavelength configuration for an optical encoder readhead including dual optical path region with an optical path length difference
A readhead and scale arrangement comprises: a readhead comprising a light source configured to output diverging source light comprising a plurality of individually detected wavelengths and at least a first optical signal receiver channel configured to provide a first set of position signals; and a scale track extending along the measuring axis direction on a scale member comprising a scale grating, the scale track configured to diffract the first diverging source light to provide first and second diffracted scale light portions of each of the individually detected wavelengths to the first optical signal receiver channel which provide interference fringes. The readhead comprises an optical path difference element, arranged such that respective wavelengths undergo different phase shifts. Such an encoder is robust to scale track contamination and other signal degradation. |
| US08772705B2 |
Interpolation circuitry for optical encoders
Disclosed are various embodiments of circuitry and methods for generating interpolated signals in an optical encoder. The optical encoder configurations and circuitry disclosed herein permit very high resolution reflective optical encoders in small packages to be provided. Methods of making and using such optical encoders are also disclosed. According to one embodiment, the interpolated signals are generated through the use of signal generation circuitry, peak voltage generation circuitry, reference voltage generation circuitry, slope detection circuitry, and a clocked comparator that is configured to output interpolated output pulses. |
| US08772702B2 |
Detector
A detector contains a housing with at least one window for allowing radiation to enter, at least one outlook sensor for sensing entered radiation, a unit for processing outlook sensor signals, and outlook mirrors that are shaped and mounted in the housing for reflecting onto the outlook sensor radiation from outside detection zones better than radiation from elsewhere. At least some of the outlook mirrors face the window and in operative orientation neighbor each other vertically. The detector further contains one or more window sensors for sensing radiation indicative of the window being masked or having been damaged and a unit for processing window sensor signals. A gap between at least two of the outlook mirrors allows radiation to travel between the window and at least one window sensor or accordant window sender or both. |
| US08772689B2 |
Omnidirectional sun position sensing device with a plurality of optical sensors
A method is provided to track the sun. An omnidirectional sensor is used for acquiring sun's position. The sensor can track sun's position in an omnidirectional way. A controller is also provided to control the tracking. When the sun shines strongly, the sensor is controlled to track the sun's position. When the sun does not shine strongly, the tracking is stopped. Thus, the cost for tracking the sun's position is reduced and accuracy of the tracking is enhanced. |
| US08772686B2 |
Shielding system for microwave ovens and microwave oven using this shielding system
A shielding system for microwave ovens includes a first layer of parallel grounded conductors and a second layer of parallel grounded conductors substantially perpendicular to the conductors of the first layer and, for high frequency, electrically insulated therefrom, each layer presenting a plurality of parallel metal wires connected at one end and grounded. |
| US08772682B2 |
Methods and apparatus for controlling temperature of a multi-zone heater in a process chamber
Methods and apparatus for controlling the temperature of multi-zone heater in a process chamber are provided herein. In some embodiments, a method is provided to control a multi-zone heater disposed in a substrate support, wherein the multi-zone heater has a first zone and a second zone. In some embodiments, the method may include measuring a current drawn by the first zone at a first time; measuring a voltage drawn by the first zone at the first time; calculating the resistance of the first zone based upon the measured current and voltage drawn by the first zone at the first time; determining a temperature of the first zone based upon a predetermined relationship between the resistance and the temperature of the first zone; and adjusting the temperature of the first zone in response to the temperature determination. |
| US08772680B2 |
Adaptive temperature controller
The adaptive temperature controller system includes a device for measuring resistance, an electrically-conductive material, a power supply, and a device for controlling power. In operation, the controller determines the resistance of material at one or more temperatures and therefore determines the resistance of the material through a range of operating temperature. Based on such determination so long as voltage and power are known, the resistance of the material, and therefore its temperature, are known. As a result the voltage or power may be instantly varied to produce near infinite control over material temperature. |
| US08772679B2 |
Method and system for controlling a heating element with temperature sensitive conductive layer
Methods and system for controlling a heater conductor in a heating element including a sensor conductor separated from the heater conductor by an NTC layer. The heating element is coupled to a control circuit and the flow of electricity from a direct current source through the circuit is controlled such that a change of the resistance of the NTC layer is indicative of the temperature of the heater conductor. This resistance is detected based on a time or amplitude analysis and based thereon, a heating mode of the heater conductor is controlled. In a variation, the circuit is operated in a two-period measurement mode wherein the energy transferred through the NTC layer in one period is equal and opposite to the energy transferred through the NTC layer in the other period. |
| US08772676B2 |
Heating blanket
An electric heating blanket including a flexible sheet-like heating element and a shell. The shell covers the heating blanket and includes two sheets of flexible material welded together. |
| US08772666B2 |
Interlock system for switchgear
An interlock system for a circuit-interrupting device. The circuit-interrupting device includes a gearbox, a load-breaker in series with a visible disconnect, and an assembly driving the visible disconnect between an open state and a closed state. The interlock system includes a cam and a bias-driven follower. The cam is coupled to a shaft and is driven by the shaft between a first cam state when the load-breaker is in an open state and a second cam state when the load-breaker is in a closed state. The bias-driven follower has a first follower state when the cam is in the first cam state and has a second follower state when the cam is in the second cam state. In the second follower state, the bias-driven follower blocks movement of at least one component of the assembly. The cam and the bias-driver follower are positioned inside the gearbox. |
| US08772665B2 |
Circuit breaker with arc extinguishing mechanism
A circuit breaker having an arc extinguishing mechanism includes a plurality of grids disposed in a longitudinal direction, each having protruding portions at both ends thereof so as to define a space therebetween, a fixing portion to support the grids, insulating plates fixed to both sides of the grids, a stator located below the grids, the stator including an arc runner and a stationary contact disposed at an upper side of the arc runner, and a mover contactable with or separated from the stationary contact with moving up and down within the space, wherein an interval between the insulating plates within the space is shorter than a width of the mover. |
| US08772664B2 |
Method and device for sorting flat mail items
A method is specified for sorting flat mail items, which allows sorting according to delivery order to be carried out swiftly and reliably. With the method a first sorting pass is carried out in a first segment with at least N storage modules of a sorting device and a second sorting pass is then carried out in a second segment with at least N storage modules of the sorting device. The overflow items, which are assigned to a storage module that has been closed because it is full, are deposited into one of the other storage modules in the first sorting pass and are included in the sorting process of the second sorting pass. |
| US08772659B2 |
Electronic apparatus
Key impact noise produced during data entry operations is abated with a configuration in which the deformable portion of the resilient member can abut the bottom surface of the key top and a gap is formed between the key top and the membrane sheet when the key top is displaced to the lowered position. This allows for the key top to be prevented from abutting the membrane sheet when the key top is displaced by the user from the raised position to the lowered position. As a result, the noise of collision between the key top and the membrane sheet is no longer produced and the key impact noise of the keyboard can be diminished. |
| US08772656B2 |
Acceleration switch
An acceleration switch has a mass body having a space inside, and a counter electrode provided in the space of the mass body. An arc-shaped beam surrounds and supports the mass body. The acceleration sensitivity threshold of the acceleration switch is determined by a cut portion in the mass body or by the area of the top surface of the mass body. In this manner, a plurality of acceleration switches each having a single acceleration sensitivity threshold, for example, in steps of 0.2 G, can be prepared. |
| US08772650B2 |
Systems and methods for coupling sections of an electronic device
This is directed to systems and methods for coupling sections of an electronic device together. Sections of an electronic device can be coupled together via “knuckles.” The particular shape and structure of the knuckles can be based on various design considerations. For example, in some embodiments each section can function as an individual antenna. In this case, the knuckles can be designed in order to provide electrical isolation between the sections, thus allowing proper operation of the antennas. For example, the knuckles can be formed from a dielectric material, etc. As another design example, the knuckles can be designed in order to provide increased strength in areas of high strain, and/or to counteract torsional twisting in areas of high impact. As yet another design example, the knuckle can be designed in a manner that is aesthetically pleasing or which otherwise meets cosmetic requirements. |
| US08772643B2 |
Multilayer wiring substrate, and method of manufacturing the same
A plurality of openings are formed in a resin insulation layer on a top surface side of a wiring laminate portion, and a plurality of openings are formed in a resin insulation layer on a bottom surface side thereof. A plurality of connection terminals are disposed to correspond to the openings. Peripheral portions of terminal outer surfaces of the connection terminals are covered by the resin insulation layer on the top surface side, and peripheral portions of terminal outer surfaces of the connection terminals are covered by the resin insulation layer on the bottom surface side. Each of the second-main-surface-side connection terminals has a concave portion at the center of the terminal outer surface, and the deepest portion of the concave portion is located on the interior side in relation to the peripheral portion of the terminal outer surface. |
| US08772640B2 |
Guarded coaxial cable assembly
A guarded coaxial cable assembly including a micro-coaxial cable and at least one rail. |
| US08772638B2 |
Process for manufacturing a cable resistant to external chemical agents
Process for manufacturing a cable comprising the following steps:(a) conveying at least one conductor to an extruder apparatus;(b) extruding an insulating coating layer radially external to said at least one conductor; (c) longitudinally folding a metal tape around said extruded insulating coating layer, said metal tape bearing at least one adhesive coating layer in a radially external position; (e) extruding at least one continuous coating layer comprising at least one polyamide or a copolymer thereof around and in contact with said folded metal tape; wherein the step (e) is carried out at a draw down ratio (DDR) not higher than 2.5, preferably of from 1.2 to 2.0. |
| US08772635B2 |
Waterproof casing for an electronic device
A waterproof casing for an electronic device has a body, a cover module and multiple fixers. The body has two connecting assemblies respectively mounted on two side surfaces of the body and each connecting assembly has two wings and a trough defined between the wings and the corresponding side surface of the body. The cover module has a first cover and a second cover respectively mounted on two ends of the body. The fixers are respectively inserted into a corresponding one of the first cover or the second cove and are steadily mounted with the body. The types of the cover module can be changed to fit with an electronic device installed in the body. Therefore, the combination between the body and the cover module is variable, and the waterproof casing has good applicability. |
| US08772630B2 |
Solar cell and method of manufacturing the same
The present invention relates to solar cells. Such solar cells include a substrate containing a first impurity of a first conductive type and having a textured surface with a plurality of jagged portions. Such solar cells also have an emitter layer positioned on the textured surface and containing a second impurity of a second conductive type opposite to the first conductive type, a first electrode having a plurality of first metal particles, electrically connected to the emitter layer, and a second electrode electrically connected to the substrate. The diameter of the first metal particles is larger than the peak-to-peak distance between adjacent jagged portions. |
| US08772626B2 |
Nanostructures and methods for manufacturing the same
A solar cell may include an electrically conducting substrate, a plurality of nanowhiskers extending from the substrate and a transparent electrode extending over free ends of the nanowhiskers and making electrical contact with them. Each nanowhisker may have a column with a diameter of nanometer dimension. The column may include a first p-doped semiconductor lengthwise segment and a second n-doped semiconductor lengthwise segment. The first and second semiconductor segments may have an interface between them, which forms a p-n junction. The nanowhiskers may be encapsulated in a transparent material. |
| US08772625B2 |
Encapsulating material for solar cell and solar cell module
Disclosed is an encapsulating material for solar cell containing an ethylene/α-olefin copolymer satisfying the following requirements (a1) to (a4): (a1) the content ratio of structural units derived from ethylene is from 80 to 90 mol % and the content ratio of structural units derived from α-olefin having 3 to 20 carbon atoms is from 10 to 20 mol %; (a2) MFR is from 10 to 50 g/10 minutes as measured under the conditions of a temperature of 190 degrees centigrade and a load of 2.16 kg in accordance with ASTM D1238; (a3) the density is from 0.865 to 0.884 g/cm3 as measured in accordance with ASTM D1505; and (a4) the shore A hardness is from 60 to 85 as measured in accordance with ASTM D2240. |
| US08772621B2 |
System and method for capture and rendering of performance on synthetic string instrument
Synthetic multi-string musical instruments have been developed for capturing and rendering musical performances on handheld or other portable devices in which a multi-touch sensitive display provides one of the input vectors for an expressive performance by a user or musician. Visual cues may be provided on the multi-touch sensitive display to guide the user in a performance based on a musical score. Alternatively, or in addition, uncued freestyle modes of operation may be provided. In either case, it is not the musical score that drives digital synthesis and audible rendering of the synthetic multi-string musical instrument. Rather, it is the stream of user gestures captured at least in part using the multi-touch sensitive display that drives the digital synthesis and audible rendering. |
| US08772619B2 |
Optoelectronic pickup for musical instruments
An optoelectronic pickup for a musical instrument includes at least one light source which directs light to impinge a sound generating element of the musical instrument in at least one photoreceiver located to detect the reflected light, so as to generate an electrical signal that is responsive to sound generating element movement. |
| US08772618B2 |
Mixing automatic accompaniment input and musical device input during a loop recording
Provided are a method, electronic musical instrument, and computer storage device for mixing automatic accompaniment input and musical device input during a loop recording. During a first loop recording, automatic accompaniment information is generated from a storage device having patterns of automatic accompaniment information. First musical device input is received from at least one coupled musical device. The first musical device input and the automatic accompaniment input based on the generated automatic accompaniment information are mixed to produce a first mixed output. The first mixed output in a recording memory. During a second loop recording following the first loop recording, the first mixed output is outputted from the recording memory. Second musical device input from the at least one coupled musical device is received while outputting the first mixed output. The received second musical device input and the first mixed output are mixed to produce second mixed output. The second mixed output is stored in the recording memory. |
| US08772617B1 |
Drum tuner
A drum tuner is described. The drum tuner includes: (i) a hub gear; (ii) two or more differential gears communicatively coupled to the hub gear and at least one of the two or more differential gears capable of engaging a tuning mechanism of a drum; and (iii) wherein, during an operational state of the drum tuner, rotation of the hub gear rotates at least one of the two or more differential gears to activate the drum's tuning mechanism. |
| US08772611B1 |
Wheat variety W020088N1
A wheat variety designated W020088N1, the plants and seeds of wheat variety W020088N1, methods for producing a wheat plant produced by crossing the variety W020088N1 with another wheat plant, and hybrid wheat seeds and plants produced by crossing the variety W020088N1 with another wheat line or plant, and the creation of variants by mutagenesis or transformation of variety W020088N1. This invention also relates to methods for producing other wheat varieties or breeding lines derived from wheat variety W020088N1 and to wheat varieties or breeding lines produced by those methods. |
| US08772609B1 |
Maize hybrid X08C986
A novel maize variety designated X08C986 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X08C986 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X08C986 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X08C986, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X08C986. This invention further relates to methods for producing maize varieties derived from maize variety X08C986. |
| US08772608B1 |
Maize hybrid X13B660
A novel maize variety designated X13B660 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X13B660 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X13B660 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X13B660, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X13B660. This invention further relates to methods for producing maize varieties derived from maize variety X13B660. |
| US08772606B2 |
Non-transgenic tomato varieties having increased shelf life post-harvest
A series of independent human-induced, non-transgenic mutations found in at least one non-ripening (NOR) gene of tomato; tomato plants having these mutations in at least one of their NOR genes; and a method of creating and identifying similar and/or additional mutations in the NOR gene by screening pooled and/or individual tomato plants. The tomato plants of the present invention exhibit fruit that ripen more slowly, rot more slowly, are firmer, and have a longer shelf life post-harvest as a result of non-transgenic mutations in at least one of their NOR genes. |
| US08772605B2 |
Cotton variety 09R348B2R2
The invention relates to the novel cotton variety designated 09R348B2R2. Provided by the invention are the seeds, plants, plant parts and derivatives of the cotton variety 09R348B2R2. Also provided by the invention are tissue cultures of the cotton variety 09R348B2R2 and the plants regenerated therefrom. Still further provided by the invention are methods for producing cotton plants by crossing the cotton variety 09R348B2R2 with itself or another cotton variety and plants produced by such methods. |
| US08772603B1 |
Soybean cultivar S120116
A soybean cultivar designated S120116 is disclosed. The invention relates to the seeds of soybean cultivar S120116, to the plants of soybean cultivar S120116, to the plant parts of soybean cultivar S120116, and to methods for producing progeny of soybean cultivar S120116. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S120116. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S120116, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S120116 with another soybean cultivar. |
| US08772598B1 |
Soybean cultivar 29124801
A soybean cultivar designated 29124801 is disclosed. The invention relates to the seeds of soybean cultivar 29124801, to the plants of soybean cultivar 29124801, to the plant parts of soybean cultivar 29124801, and to methods for producing progeny of soybean cultivar 29124801. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 29124801. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 29124801, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 29124801 with another soybean cultivar. |
| US08772595B2 |
Soybean variety A1026828
The invention relates to the soybean variety designated A1026828. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026828. Also provided by the invention are tissue cultures of the soybean variety A1026828 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026828 with itself or another soybean variety and plants produced by such methods. |
| US08772592B2 |
Soybean variety A1026583
The invention relates to the soybean variety designated A1026583. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026583. Also provided by the invention are tissue cultures of the soybean variety A1026583 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026583 with itself or another soybean variety and plants produced by such methods. |
| US08772589B2 |
Soybean variety D2011912
The invention relates to the soybean variety designated D2011912. Provided by the invention are the seeds, plants and derivatives of the soybean variety D2011912. Also provided by the invention are tissue cultures of the soybean variety D2011912 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety D2011912 with itself or another soybean variety and plants produced by such methods. |
| US08772588B2 |
Soybean variety A1026305
The invention relates to the soybean variety designated A1026305. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026305. Also provided by the invention are tissue cultures of the soybean variety A1026305 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026305 with itself or another soybean variety and plants produced by such methods. |
| US08772579B2 |
Lettuce variety emerson
The present invention relates to a new lettuce (Lactuca sativa) variety, seed designated as 79-11 RZ, which exhibits a combination of an extraordinary high number of leaves, resistance to many Bremia-races, and an extraordinary low number of apices under many growing conditions, the representative seed having been deposited with the National Collections of Industrial, Marine and Food Bacteria (NCIMB) in Bucksburn, Aberdeen AB21 9YA, Scotland, UK and assigned NCIMB Accession No. 41614, The present invention also relates to a Lactuca sativa plant produced by growing the 79-11 RZ (Emerson) seed. The invention further relates to methods for producing the lettuce cultivar, represented by lettuce variety 79-11 RZ. |
| US08772577B2 |
Bacillus thuringiensis gene with lepidopteran activity
The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Lepidoptera. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests. |
| US08772575B2 |
Nucleic acids useful in the manufacture of oil
Novel gene sequences from microalgae are disclosed, as well as novel gene sequences useful in the manufacture of triglyceride oils. Also disclosed are sequences and vectors that allow microalgae to be cultivated on sugar cane and sugar beets as a feedstock. In some embodiments, the vectors are useful for the purpose of performing targeted modifications to the nuclear genome of heterotrophic microalgae. |
| US08772574B2 |
Spinach hybrid RX 06691714 and parents thereof
The invention provides seed and plants of spinach hybrid RX 06691714 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of spinach hybrid RX 06691714 and the parent lines thereof, and to methods for producing a spinach plant produced by crossing such plants with themselves or with another spinach plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the leaf and gametes of such plants. |
| US08772572B2 |
Methods and materials for conferring resistance to pests and pathogens of plants
Methods and materials for conferring pest resistance to plants are provided. Plants are transformed with a silencing construct homologous to a gene of a plant pest that is essential for the survival, development, or pathogenicity of the pest. This results in the plant producing RNAi to the selected gene, which, when ingested by the pest results in silencing of the gene and a subsequent reduction of the pest's ability to harm the plant. In other embodiments, the pest's reduced ability to harm the plant is passed on to pest progeny. Methods and materials for depathogenesis of pests is also provided. |
| US08772569B2 |
Edge fold having substantially uniform gathers for absorbent article and method for making
An absorbent article may have an edge fold having substantially uniform gathers. The edge fold may form a finished edge cuff. The finished edge cuff may be formed around and/or along a portion of a longitudinal edge. The edge fold may be formed by folding and seaming existing material (i.e., without the addition of a discrete part). The edge fold may be extensible, or elastic. The edge fold may completely encircle the portion of the longitudinal edge that defines the leg opening of a diaper. A method and an apparatus for forming an edge fold are also provided. |
| US08772566B2 |
Method of making nanostructured glass-ceramic waste forms
A waste form for and a method of rendering hazardous materials less dangerous is disclosed that includes fixing the hazardous material in nanopores of a nanoporous material, reacting the trapped hazardous material to render it less volatile/soluble, and vitrifying the nanoporous material containing the less volatile/soluble hazardous material. |
| US08772565B1 |
Method of recycling radioactive waste acid
A radioactive waste acid is recycled. The waste acid is a fluoboric waste acid. The waste acid contains a lot of oxides and radioactive nuclei. The waste fluoboric acid is processed to obtain a purified fluoboric acid. The amount of radioactive nuclei is greatly reduced. Thus, the present invention has a simple procedure with low cost and reduced power consumption. |
| US08772558B2 |
Methods and apparatuses for producing aromatic hydrocarbon-containing effluent
Embodiments of methods and apparatuses for producing an aromatic hydrocarbon-containing effluent are provided herein. The method comprises the step of rapidly heating a biomass-based feedstock to a first predetermined temperature of from about 300 to about 650° C. in the presence of a catalyst, hydrogen, and an organic solvent within a time period of about 20 minutes or less to form the aromatic hydrocarbon-containing effluent. The biomass-based feedstock comprises lignocellulosic material, lignin, or a combination thereof. |
| US08772552B2 |
Process for the selective hydroxylation of benzene with molecular oxygen
The present invention provides an improved process for the selective hydroxylation of benzene. The process provides a direct single step selective vapor phase hydroxylation of benzene to phenol using molecular oxygen (air) over Cu—Cr oxide catalysts. The process provides benzene conversion of 10 to 45% and selectivity for phenol up to 100%. |
| US08772547B2 |
Method for producing 1-adamantyl trimethylammonium hydroxide
The present invention relates to a process for preparing 1-adamantyltrimethylammonium hydroxide, by A) reacting 1-adamantyldimethylamine with dimethyl sulfate to give 1-adamantyltrimethylammonium sulfate; and B) subjecting the 1-adamantyltrimethylammonium sulfate obtained in A) to anion exchange with an ion exchanger loaded with OH ions. |
| US08772546B2 |
1,2-diaminocyclohexane and chemical process
Disclosed is a process for the preparation of 1,2-cycloaliphatic diamines from 1,2-aromatic diamines. In one embodiment, the process provides a method for making 1,2-diaminocyclohexane by the reaction of 1,2-phenylenediamine contained in a polar, protic solvent with hydrogen in the presence of a supported rhodium catalyst, ammonia, and an inorganic borohydride, and having enhanced overall conversion and selectivity. |
| US08772545B2 |
Rinsable dyes and methods for their preparation
Rinsable dyes with improved fugitivity are formulated by attaching dyestuff compounds with amine-capped sulfonic solubilizing groups to commercially available ethoxylated aniline, so that the surfactant effect of the ethoxylated aniline counteracts the substantivity of the dyestuff compound, while the neutralization of the sulfonic solubilizing groups reduces substantivity. |
| US08772543B2 |
Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof
Antiproliferative compounds having a structure represented by formula (II), where n, R1, R2, R3, R4, and R5 are as defined herein, can be used to treat tumors, optionally when conjugated to a ligand such as an antibody: |
| US08772541B2 |
Cannabinoid receptor 2 (CB2) inverse agonists and therapeutic potential for multiple myeloma and osteoporosis bone diseases
Cannabionid receptor-2 inverse antagonists include compounds represented by Formula IV, or a pharmaceutically acceptable salt thereof: wherein: R1 and R2 are independently H, alkyl, or alkenyl; R3 is alkyl, alkenyl, aryl, aralkyl, aralkenyl, heterocyclyl, heterocyclylalkyl, heteroaryl, heteroarylalkyl; R4 and R5 are independently a bond, alkylenyl, or alkenylenyl; each R6 and R7 is independently selected from the group consisting of OH, F, Cl, Br, I, (C1-C6)alkyl, alkoxy, amino, COOH, CONH2, SO3H, PO3H2, CN, SH, NO2 and CF3; and p and q are independently 0, 1, 2, 3, 4, or 5. Such compounds may be used to treat osteoporosis or multiple myeloma. |
| US08772537B2 |
Process for producing aminoalkylthiosulfuric acid compound
An aminoalkylthiosulfuric acid compound represented by formula (1): is produced. In step (A1), a hydrochloride of a chloroalkylamine compound represented by formula (2): is reacted with an alkali metal salt of thiosulfuric acid in the presence of 2 to 6 parts by weight of water with respect to 1 part by weight of the hydrochloride between 50° C. and 100° C. R1 and R2 each represents a hydrogen atom and the like, and n represents an integer of 2 to 9. In step (B1), a mixture of a solid containing the aminoalkylthiosulfuric acid compound and a liquid containing an alkali metal chloride is obtained by adjusting the temperature of the mixture of step (A1) to between −15° C. and 50° C. In step (C1), the aminoalkylthiosulfuric acid compound is obtained as solid by separating the solid containing the aminoalkylthiosulfuric acid compound and the liquid containing the alkali metal chloride from the mixture of (B1). |
| US08772528B2 |
Method for producing aminothiazole derivative and production intermediate
Provided is a method for selectively demethylating a 2-methoxy group. Specifically provided is a production method of a compound represented by formula (7) below through the following reactions. |
| US08772525B2 |
Method for preparing a diorganodihalosilane
A method of preparing a diorganodihalosilane comprising the separate and consecutive steps of (i) contacting a copper catalyst with a mixture comprising hydrogen gas and a silicon tetrahalide at a temperature of from 500 to 1400° C. to form a silicon-containing copper catalyst comprising at least 0.1% (w/w) of silicon, wherein the copper catalyst is selected from copper and a mixture comprising copper and at least one element selected from gold, magnesium, calcium, cesium, tin, and sulfur; and (ii) contacting the silicon-containing copper catalyst with an organohalide at a temperature of from 100 to 600° C. to form at least one diorganodihalosilane. |
| US08772523B2 |
Multifunctional chain shuttling agents
The invention generally relates to chain shuttling agents (CSAs), a process of preparing the CSAs, a composition comprising a CSA and a catalyst, a process of preparing the composition, a processes of preparing polyolefins, end functional polyolefins, and telechelic polyolefins with the composition, and the polyolefins, end functional polyolefins, and telechelic polyolefins prepared by the processes. |
| US08772521B2 |
Metal alkyl-arenes and processes for the preparation thereof
Metal alkyl-arene having general formula (I) or (Ia): M (η6-arene)2AlqXrRs (I) M (η6-arene)AlqXrRs (Ia) wherein: —M represents zirconium (Zr), hafnium (Hf), or mixtures thereof, preferably zirconium; —arene represents a benzene, or a benzene 10 substituted with from 1 to 6 linear or branched C1-C6 alkyl groups, or mixtures thereof; —X represents a halogen atom selected from chlorine, bromine, fluorine, iodine, preferably chlorine; —R represents a linear or branched C1-C15 alkyl group; —q is a number ranging from 2 to 6, preferably 3 for a metal alkyl-arene having general formula (I), 2 for a metal alkyl-arene having general formula (Ia); —r is a number ranging from 1 to 20, preferably 9 for a metal alkyl-arene having general formula (I), 6 for a metal alkyl-arene having general formula (Ia); —s is a number ranging from 1 to 6, preferably 2. Said metal alkyl-arene can be advantageously used for the preparation of solid components of catalysts for the (co)polymerization of α-olefins. |
| US08772519B2 |
Process for preparing mono-allyl-functionalized dialkylphosphinic acids, salts and esters thereof with allylic compounds, and the use thereof
The invention relates to a process for preparing mono-allyl-functionalized dialkylphosphinic acids, esters and salts with allylic compounds, characterized in that a) a phosphinic acid source (I) is reacted with olefins (IV) in the presence of a catalyst A to give an alkylphosphonous acid, or salt or ester thereof (II), b) the alkylphosphonous acid, or salt or ester thereof (II) thus formed is reacted with allylic compounds of the formula (V) in the presence of a catalyst B and of a base to give a mono-allyl-functionalized dialkylphosphinic acid derivative (III), where R1, R2, R3, R4, R5, R6, R7, R8, R9 are the same or different and are each independently, inter alia, H, C1-C18-alkyl, C6-C18-aryl, C6-C18-aralkyl, C6-C18-alkylaryl, and X is H, C1-C18-alkyl, C6-C18-aryl, C6-C18-aralkyl, C6-C18-alkylaryl, Mg, Ca, Al, Sb, Sn, Ge, Ti, Fe, Zr, Zn, Ce, Bi, Sr, Mn, Cu, Ni, Li, Na, K and/or a protonated nitrogen base, and the catalysts A and B are transition metals and/or transition metal compounds and/or catalyst systems which are composed of a transition metal and/or a transition metal compound and at least one ligand. |
| US08772514B2 |
Preparation of furfural compounds, and mixture for preparing the same
A method of preparing furfural compounds and a mixture for preparing the same are disclosed. First, a solution is prepared by mixing an organic ammonium salt and a hydroxyl organic solvent. Then, a carbohydrate is mixed with the solution to form a mixture. The mixture is heated to a reaction temperature for conversion of the carbohydrate to produce the furfural compounds. |
| US08772513B2 |
Oxidation process to produce a crude dry carboxylic acid product
Disclosed is a process to produce a dry purified carboxylic acid product comprising furan-2,5-dicarboxylic acid (FDCA). The process comprises oxidizing at least one oxidizable compound selected from the following group: 5-(hydroxymethyl)furfural (5-HMF), 5-HMF esters (5-R(CO)OCH2-furfural where R=alkyl, cycloalkyl and aryl), 5-HMF ethers (5-R′OCH2-furfural, where R′=alkyl, cycloalkyl and aryl), 5-alkyl furfurals (5-R″-furfural, where R″=alkyl, cycloalkyl and aryl), mixed feed-stocks of 5-HMF and 5-HMF esters and mixed feed-stocks of 5-HMF and 5-HMF ethers and mixed feed-stocks of 5-HMF and 5-alkyl furfurals to generate a crude carboxylic acid slurry comprising FDCA, cooling a crude carboxylic acid slurry in cooling zone to form a cooled slurry stream. The cooled slurry stream is routed to a solid-liquid separation zone to generate a crude wet cake stream comprising FDCA that is dried in a drying zone to generate a dry carboxylic acid product stream comprising crude FDCA (cFDCA). |
| US08772511B2 |
Azabicyclic carbamates and their use as alpha-7 nicotinic acetylcholine receptor agonists
The invention relates to novel benzothiophene-, benzofuran-, and indole ureas and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning, and/or memory. |
| US08772508B2 |
Inhibitors of glutaminyl cyclase
Compounds of formula (I), combinations and uses thereof for disease therapy, or a pharmaceutically acceptable salt, solvate or polymorph thereof, including all tautomers, stereoisomers and polymorphs thereof, wherein A, B and R1 are as defined throughout the description and the claims. |
| US08772507B2 |
Imidazole-benzamide anti-cancer agents
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed. |
| US08772497B2 |
Method for producing 1, 2-dihydropyridine-2-one compound
The present inventions provide a method for commercially producing a 1,2-dihydropyridine-2-one compound represented by the following formula (III-a) wherein the ring A represents an optionally substituted 2-pyridyl group, the ring B represents an optionally substituted phenyl group, and the ring C represents an optionally substituted phenyl group. Further, the invention provides crystals of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one and production processes therefore. |
| US08772494B2 |
N-aryl piperidine substituted biphenylcarboxamides as inhibitors of apolipoprotein b
N-aryl piperidine substituted biphenylcarboxamides compounds of formula (I) methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes. |
| US08772493B2 |
Compounds having auditory protective effect
The present invention relates to a compound represented by formula 1 in the present specification or a pharmaceutically acceptable thereof, which inhibits an apoptosis mechanism of auditory hair cells for various ototoxicities leading to deafness, and protects the auditory organ and hearing, a method for preparation thereof, and a composition containing the same. |
| US08772492B2 |
Substituted isoquinoline and isoquinolinone derivatives
The invention relates to 6-substituted isoquinoline and isoquinoline derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds. |
| US08772491B2 |
Process for the preparation of solifenacin succinate
The present invention relates to a process for the preparation of Solifenacin succinate by condensing a compound of formula (IVb) with (RS)-3-quinuclidinol, wherein, R represents methyl, ethyl, isopropyl; to produce a diastereomeric mixture of (1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic acid (3RS)-1-azabicyclo[2.2.2]oct-3-yl ester, which is treated with succinic acid in a solvent or mixture of solvents to produce optically pure Solifenacin succinate, Formula (X). |
| US08772490B2 |
Optically active diazabicyclooctane derivatives and process for preparing the same
Provided are an optically active diazabicyclooctane derivative defined by formula (F) below, which is useful as a pharmaceutical intermediate for β-lactamase inhibitor, and a process for preparing the same. In formula (F) above, R1 represents CO2R, CO2M, or CONH2, wherein R represents a methyl group, a tert-butyl group, an allyl group, a benzyl group, or a 2,5-dioxopyrrolidin-1-yl group, and M represents a hydrogen atom, an inorganic cation, or an organic cation; and R2 represents a benzyl group or an allyl group. |
| US08772484B2 |
Process for producing benzo[f]quinoxaline compounds
A simple process for producing v-coelenterazine compounds has been desired. Described is a process for producing a v-coelenterazine compound represented by general formula (II) comprising (1) the step of reacting a compound of general formula (VIII) with a methyltriphenylphosphonium salt in the presence of a base to give a compound represented by general formula (IX), (2) the step of performing a ring-closing metathesis reaction on any one selected from the group consisting of the compound represented by general formula (IX) and a compound of general formula (X) which is the compound of general formula (IX) wherein the amino is protected with R5, and then deprotecting R4 and, if any, R5 to give a v-coelenteramine compound represented by general formula (XIV), and (3) the step of reacting the compound of general formula (XIV) with a compound represented by general formula (XV) to give the compound of general formula (II). |
| US08772481B2 |
Aza- and diaza-phthalazine compounds as P38 map kinase modulators and methods of use thereof
The present invention comprises a new class of compounds useful for the prophylaxis and treatments of protein kinase mediated diseases, including inflammation and related conditions. |
| US08772477B2 |
Process for preparing lactams
A method for preparing lactams by cyclizing hydrolysis of a corresponding aminonitrile is described. A method for manufacturing a lactam by reacting an aminonitrile with water in the presence of a catalyst involving placing the water and the aminonitrile in contact in vapor phase, passing the mixture of vapors through a bed of catalyst arranged in at least one tube forming a reaction chamber and recovering the lactam at the outlet of the tube is also described. |
| US08772475B2 |
AZA compounds and production method thereof, and metal complexes as MRI contrast agents
A core of a cyclic structure represented by (—N—(CH2)n—)k is bonded to a dendrimer-type side chain with a specific branched structure at all nitrogen atoms in the core to produce a compound with a specific structure for producing a metal complex that exhibits a T1-reducing effect, and the resulting compound is coordinated to a metal ion that has a T1-reducing effect to obtain a metal complex that exhibits an excellent T1-reducing effect which is useful as an effective component of an MRI contrast agent and an MRI contrast agent using the same. |
| US08772474B2 |
Cyclic nucleotide analogs
Disclosed herein are cyclic nucleotide analogs, methods of synthesizing cyclic nucleotide analogs and methods of treating diseases and/or conditions such as viral infections, cancer, and/or parasitic diseases with cyclic nucleotide analogs. |
| US08772472B2 |
SiRNA conjugate and preparation method thereof
Provided are an siRNA-polymer conjugate, and a method for preparing the same, and more specifically, to a hybrid conjugate formed by covalently bonding siRNA and a polymeric compound for improving the in vivo stability of siRNA, and to a preparation method of the hybrid conjugate. The conjugate of the present invention can improve the in vivo stability of siRNA, thereby achieving an efficient delivery of therapeutic siRNA into cells and exhibiting the activity of siRNA even with a small dose of a relative low concentration. Therefore, the conjugate can advantageously be used as not only an siRNA treatment tool for cancers and other infectious disease, but also a novel type siRNA delivery system. |
| US08772470B1 |
Compositions and methods for treatment of prostate and other cancers
Therapeutic agents which target heat shock protein (hsp) 27 in vivo are used to provide treatment to individuals, particularly human individuals, suffering from prostate cancer and other cancers that overexpress hsp27. A therapeutic agent, for example an antisense oligonucleotide or RNAi nucleotide inhibitor with sequence specificity for hsp27 mRNA, for example human hsp27 mRNA, is administered to an individual suffering from prostate cancer or some other cancer expressing elevated levels of hsp 27 in a therapeutically effective amount. The therapeutic agent is suitably formulated into a pharmaceutical composition which includes a pharmaceutically acceptable carrier, and packaged in dosage unit form. A preferred dosage unit form is an injectable dosage unit form. |
| US08772469B2 |
Synthetic double-stranded oligonucleotides for specific inhibition of gene expression
The present invention relates to oligonucleotide derivatives which are at least partly double-stranded and which have a 2′5′-linked oligonucleotide residue on at least one 3′ end and to the use thereof for specific inhibition of gene expression. |
| US08772465B2 |
IRES functioning in plant
It is intended to provide for a polycistronic expression pattern in a plant used as a host. The present invention provides a polynucleotide which comprises the following DNA (a) or (b) and functions as an IRES (internal ribosome entry site) in a plant: (a) DNA of the nucleotide sequence represented by SEQ ID NO: 1, 2, 3, or 4; or (b) DNA of a nucleotide sequence derived from the nucleotide sequence represented by SEQ ID NO: 1, 2, 3, or 4 by the substitution, deletion, addition, and insertion of one or more bases and having a function of positively regulating the translation of a nucleic acid located downstream thereof. |
| US08772457B2 |
BACE1 antibodies
The invention provides antibodies to specific neural proteins and methods of using the same. |
| US08772456B2 |
Fibrous protein fusion and use thereof in the formation of advanced organic/inorganic composite materials
The claimed invention provides a fusion polypeptide comprising a fibrous protein domain and a mineralization domain. The fusion is used to form an organic-inorganic composite. These organic-inorganic composites can be constructed from the nano- to the macro-scale depending on the size of the fibrous protein fusion domain used. In one embodiment, the composites can also be loaded with other compounds (e.g., dyes, drugs, enzymes) depending on the goal for the materials, to further enhance function. This can be achieved during assembly of the material or during the mineralization step in materials formation. |
| US08772454B2 |
Isolation and characterization of novel green fluorescent proteins from copepods
The isolation and characterization of two protein isoforms collected green fluorescent copepods is described herein. The new Pontella mimocerami GFP-like isoforms pmimGFP1 and pmimGFP2 of the present invention are quick to mature and rapidly produce a fluorescent signal. The two isoforms are very similar in molar extinction coefficients (ME) with 105,000 M−1 cm−1 for pmimGFP1 and 103,000 M−1cm−1 for pmimGFP2, respectively. The relative brightness of these two new copepod GFP-like proteins is the highest measured for any isolated GFP-like protein. |
| US08772453B2 |
Compositions for linking zinc finger modules
Disclosed herein are compositions for linking DNA binding modules to allow for specific and selective binding to module subsites separated by 1 or more base pairs. Also described are methods of making and using compositions comprising these linkers. |
| US08772452B2 |
Calcium-binding photoprotein
The invention provides calcium-binding photoproteins which can detect light emission with a higher sensitivity. The proteins of the invention comprising the amino acid sequence of SEQ ID NO: 2 can be used for the detection and measurement of calcium ions. The proteins of the invention are useful as reporter proteins, luminescent markers, etc. The polynucleotides of the invention are useful as reporter genes, etc. |
| US08772451B2 |
Soluble TCR molecules and methods of use
Disclosed are compositions and methods for detecting cells or tissue comprising a peptide antigen presented in the context of an MHC or HLA complex. The invention has a wide range of applications including providing a highly sensitive method for detecting cancer cells. |
| US08772449B2 |
Cell-penetrating peptides
A cell-penetrating peptide of (A) to (D) below gives cell membrane permeability and transmucosal absorbability to a physiologically active substance: (A) a peptide having the amino acid sequence of SEQ ID NO:1; (B) a peptide represented by SEQ ID NO:1 except that one or several basic amino acids are changed; (C) a peptide represented by SEQ ID NO:1 except that 1 to 5 amino acids are changed; (D) a peptide having: the reverse sequence of any of (A) to (C); an amino acid sequence which is the same as the reverse sequence of (A) except that one or several basic amino acids are changed; or an amino acid sequence which is the same as the reverse sequence of (A) except that 1 to 5 amino acids are changed. |
| US08772448B2 |
Peptides immunoreactive with autoantibodies from patients suffering from rheumatoid arthritis
The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies. |
| US08772447B2 |
Chromatography ligand comprising domain C from staphylococcus aureus protein A for antibody isolation
The present invention relates to a chromatography ligand, which comprises Domain C from Staphylococcus protein A (SpA), or a functional fragment or variant thereof. The chromatography ligand presents an advantageous capability of withstanding harsh cleaning in place (CIP) conditions, and is capable of binding Fab fragments of antibodies. The ligand may be provided with a terminal coupling group, such as arginine or cysteine, to facilitate its coupling to an insoluble carrier such as beads or a membrane. The invention also relates to a process of using the ligand in isolation of antibodies, and to a purification protocol which may include washing steps and/or regeneration with alkali. |
| US08772445B2 |
Production and use of antitumoral cyclodepsipeptides
A compound having the general structure R1, R2, R3 and R4 being selected from the group consisting of a hydrogen atom (H) and a C1-C20 alkyl, and R5 being a phenyl radical. |
| US08772444B2 |
Method for producing petroleum resin
A method for producing a petroleum resin including removing a low-molecular mist by means of a filter. |
| US08772442B2 |
Conjugated polymers and their use in optoelectronic devices
Disclosed are certain polymeric compounds and their use as organic semiconductors in organic and hybrid optical, optoelectronic, and/or electronic devices such as photovoltaic cells, light emitting diodes, light emitting transistors, and field effect transistors. The disclosed compounds can provide improved device performance, for example, as measured by power conversion efficiency, fill factor, open circuit voltage, field-effect mobility, on/off current ratios, and/or air stability when used in photovoltaic cells or transistors. The disclosed compounds can have good solubility in common solvents enabling device fabrication via solution processes. |
| US08772438B2 |
Preparation of polyamides
A process for making a polyamide polymer, said process comprising heating, in one or more ionic liquid(s), one or more polyamide precursor(s) selected from: (i) one or more free dicarboxylic acid(s) or ester(s) thereof, with one or more diamine(s); or (ii) one or more salt(s) of a dicarboxylic acid with a diamine; or (iii) one or more lactam(s); or (iv) mixtures of any of the foregoing precursors (i) to (iii). |
| US08772437B2 |
Biodegradable nitric oxide generating polymers and related biomedical devices
Disclosed herein is a biodegradable nitric oxide-generating polymer comprising a nitric oxide-releasing N2O231 (NONOate) functional group. The polymer can be applied to various medical devices for the treatment of various diseases such as thrombosis and restenosis. |
| US08772435B2 |
Dispersants
The present invention relates to dispersants for dispersing a particulate solid for millbases, paints and inks. The present invention provides a composition containing a particulate solid, a polar organic medium and a compound or salts thereof for formula T-(A)m(B)n—X—Z-Q(0-p) wherein T is hydrogen or a polymerization terminating group; A is the residue of a hydroxy carboxylic acid or lactone thereof; B is the residue of an amino carboxylic acid; X is a direct bond or a divalent group; Z is an acidic or basic group or a moiety which contains an acidic or basic group; Q is an optional residue of an oxide, urea or a dibasic acid or anhydride thereof; m and n are positive integers; and p represents the number of residual amino and/or imino groups in Z. |
| US08772434B2 |
Block polyisocyanate and urethane composition containing the same
Disclosed is a block polyisocyanate obtained by blocking at least a part of isocyanate groups of a polyisocyanate, which is derived from an aliphatic diisocyanate and a polyol and satisfies all of the conditions (1)-(5) shown below, with a pyrazole compound. (1) Average number of isocyanate groups: 3.0-20 (2) Diisocyanate monomer trimer concentration: 10-50% by mass (3) Isocyanate group concentration: 5-22% by mass (4) Polyol content concentration: 5-40% by mass (5) Diisocyanate monomer concentration: 3% by mass or less. |
| US08772432B2 |
Aqueous silane systems based on tris(alkoxysilylalkyl)amines and the use thereof
The invention relates to an aqueous composition based on tris-silylated amino-functional silicon compounds, which is substantially free of organic solvents and which substantially does not release any alcohol even during the cross-linking process, and to method for the production thereof, and to the use thereof, for example for the hydrophobization of metal, glass or mineral surfaces, such as concrete and bricks, as adhesion promoter or for rock consolidation, among other things. |
| US08772429B2 |
Biomaterial
The present invention provides a triblock copolymer and a viscoelastic biostable foam comprising the same. |
| US08772422B2 |
Polymer composites of silicone ionomers
A polymer composite composition wherein at least one of the constituents is a silicone ionomer and the other constituent is polymer. |
| US08772421B2 |
Polymers with improved strength comprising mixed oxyalkyl units
The invention relates to compositions that are produced using a mixture from two or more polyols and to a method for producing said compositions. The invention also relates to the use of said compositions as adhesives, sealing compounds, surface-coating agents, fillers or for producing molded parts. |
| US08772420B2 |
Fluorinated polyester blend
A fluorinated polyester blend is prepared by melt blending a fluorovinyl ether functionalized polyester with a non-fluorinated polyester. The fluoroether functionalized polyester can be a homopolymer or a copolymer. The blend is useful for preparing fibers, yarns, fabrics, garments, carpets, and other shaped articles. The shaped articles exhibit durable soil, oil, and water repellency. |
| US08772415B2 |
Hydrogenated block copolymers and crosslinking compositions containing the same
The disclosure provides a hydrogenated straight-chain block copolymer, obtained by selective hydrogenation of a straight-chain block copolymer. |
| US08772413B2 |
Polyacrylic acid (salt)-type water absorbent resin and method for producing of same
Disclosed is a method for producing a water absorbent resin, by which a surface-crosslinked water absorbent resin having excellent physical properties can be efficiently obtained at low cost, while assuring high productivity. When the production scale is increased to a continuous production at 1 t/hr or more, the physical properties are improved and stabilized (for example, standard deviation of the physical properties is reduced) by a surface-crosslinking treatment, and the absorption against pressure (AAP) and liquid permeability (SFC) are further improved. Specifically disclosed is a method for producing a water absorbent resin, which is characterized in that the stirring shaft of the continuous mixing apparatus for the surface-crosslinking agent is heated during the mixing step of the surface-crosslinking agent or that the continuous mixing apparatus for the surface-crosslinking agent is operated at a pressure that is reduced relative to the ambient pressure and a gas flow is passed through the mixing apparatus during the mixing of the surface-crosslinking agent so that the gas flow in the mixing apparatus is 40° C. or more (when defined with respect to the gas temperature at the exit). |
| US08772412B2 |
Meta-stable state nitrogen-containing polymer
A meta-stable state nitrogen-containing polymer formed by reacting Compound (A) and Compound (B) is described. Compound (A) is a monomer having a reactive terminal functional group. Compound (B) is a heterocyclic amino aromatic derivative as an initiator. The molar ratio of Compound (A) to Compound (B) is from 10:1 to 1:10. The meta-stable state nitrogen-containing polymer has a variance less than 2% in its narrow molecular weight distribution after being retained at 55° C. for one month. |
| US08772408B2 |
Binders containing nanoparticles
The present invention relates to aqueous binder dispersions based on silane-modified polymeric binders and inorganic nanoparticles, a process for the preparation thereof and the use thereof for the production of high quality coatings, in particular clear lacquers. |
| US08772406B2 |
Synthetic wood composite
The invention is directed a synthetic wood composite comprising biomimetic macromolecules and methods for the preparation thereof. |
| US08772403B2 |
Food grade marker
A food-grade marking composition useful for marking and labeling surfaces of food processing equipment includes a food grade base polymer, a coloring agent, and a volatile organic solvent. A marker pen is also provided which includes the food grade marking composition in combination with a delivery instrument. The food grade base polymer meets the regulatory requirements of 21 C.F.R. §175.300 for incidental food contact applications. |
| US08772399B2 |
Flexible protective and lustrous spray gel dressing composition
A protective dressing composition which imparts a lustrous and glossy appearance to a flexible or elastic rubber or plastic surface includes water, silicone fluid, a polymeric acrylic emulsifier to hold the silicone fluid in dispersion in the water and a UV stabilizer. Further, the composition is substantially free of nonpolymeric surfactants. The coating does not exhibit stickiness, attract dust or other contaminants, and resist cracking and peeling. The composition provides of a shiny protective coating suitable for application to metal, plastic, wood, and painted surfaces, and is especially well suited for use on flexible substrates such as automotive tires, bumpers, rubber, trim, vinyl, and the like. The coating maintains the flexibility of the coating at low temperatures and reduces and/or eliminates the tacky property on the surface. The acrylic polymer emulsifier does not re-emulsify with rain (water) providing a durable protective coating. The instant composition utilizes a polymer, which acts as an emulsifier and does not require a separate surfactant to hold the solution in suspension as required by conventional formulations, which require a surfactant to form an emulsion. |
| US08772390B1 |
Sprayable polymeric coating system for the protection of complex metal structures against corrosion
A method of applying a protective polymeric coating to a substrate has the steps of mixing a cellulose acetate buterate and a plasticizer and a corrosion inhibitor together to form a solid mixture, heating the solid mixture so as to form a liquid state, painting the substrate with the liquid state, and drying the liquid state on the substrate for a period of time. The step of painting can include spraying the liquid state of the mixture onto the substrate. The plasticizer is an epoxidized fatty acid ester. The corrosion inhibitor is epoxidized canola oil. Additionally, epoxidized soil bean oil, silica amorphous and titanium dioxide can be mixed together. |
| US08772388B1 |
Intermediate resin blend for improved coatings
The invention relates to a waterborne high solids emulsion resin system that can be formulated in a way to provide excellent water proofing, chemical resistance, scratch and mar resistance, resistance to hot tire pickup, while minimizing the possibility of osmotic blistering and being able to use any desired cosolvent to produce a one-coat, clear, high gloss coating or sealant for wood, cement, concrete, stone, stucco and cement-based substrates. Preferably, the resin system comprises ultra-fine particles of a hydrophobic acrylic latex copolymer resin having a high Tg temperature and a low coalescent demand that can produce a final coating or sealant at VOCs of 50 g/l or less. The acrylic resin is combined with an additional water resistance additive formed from an silane/siloxane emulsion blend of a type and amount that provides additional water resistance while simultaneously allowing water vapor pressure in the substrate to pass through the coating. |
| US08772382B2 |
Heavy metal-free stabilizer composition for halogenated polymers
The present invention relates to a stabilizer composition for halogen-containing polymers which is free from heavy metals, the use thereof in the stabilizing of halogen-containing polymers, in particular against an undesirable pink coloration, and shaped articles comprising this stabilizer composition. |
| US08772374B2 |
Preparation of silica reinforced rubber composition and tire with component thereof
The invention relates to the preparation of a rubber composition containing a pre-treated precipitated silica and a tire having a component comprised of such rubber composition. The pre-treated silica is a precipitated silica having been pre-treated with a silica coupling agent comprised of an alkoxyorganomercaptosilane to form a precipitated silica/coupling agent composite prior to its blending with a rubber composition. The rubber composition preparation involves reacting said pretreated silica/coupling agent composite with a combination of bis(3-triethoxysilylpropyl) polysulfides in situ within the rubber composition. |
| US08772371B2 |
Pearlescent pigments coated with a metal oxide/hydroxide layer and an acrylic copolymer
The invention relates to pearlescent pigments comprising a platelet-shaped substrate, a metal oxide coating comprising a metal oxide layer having a refractive index of greater than 1.8 and a protective layer, wherein the protective layer comprises a metal oxide/hydroxide layer and optionally boroxide, applied to which is an organic aftercoat of an acrylic copolymer, to a method for producing said pigments and the use thereof. The outer layer provides a very good photo-stabilisation of the TiO2 coated platelet-shaped substrates, such as mica, combined with a good water resistance and an anti-yellowing performance. |
| US08772370B1 |
Antifreeze agent for tire sealants
An environmentally safe, biodegradable aqueous antifreeze solution and a puncture sealing composition containing the same are provided. The antifreeze solution includes an antifreeze agent selected from trimethylglycine, dimethyl sulfoxide, and derivatives and combinations thereof. The composition is effective in forming and maintaining seals in tube and tire punctures. |
| US08772368B2 |
Bioabsorbable blend for temporary scaffolding of the blood vessel wall
A bioabsorbable blend comprising poly(L-lactide) (PLLA) and a phosphorylcholine group-containing copolymer (PPCP) capable of enduring the mechanical strength of blood vessel walls and applicable for fabricating cardiovascular devices was developed. The blend acts as a scaffold to support blood vessel walls during vascular healing and undergoes biodegradation in vivo after vascular healing is complete. Furthermore, the blend can prevent the formation and adsorption of thrombi. |
| US08772365B2 |
Resin composition for foams and uses thereof
The present invention provides a resin composition capable of providing foams (non-crosslinked and crosslinked foams) which have low specific gravity and low compression set (CS) and are excellent in tensile strength properties, tear strength properties and vibration-damping properties at room temperature to high temperatures, and a foam of the resin composition. The resin composition for foams of the present invention comprises 5 to 95 parts by weight of an ethylene/α-olefin copolymer (A) and 5 to 95 parts by weight of a hydrogenated copolymer (B) obtained by hydrogenating a copolymer comprising a conjugated diene and a vinyl aromatic compound, and is characterized in that the hydrogenated copolymer (B) does not have a glass transition point of not higher than −10° C. when measured at a frequency of 1 Hz in accordance with JIS-K7198. |
| US08772363B2 |
Carrier for fluid treatment and method of making the same
A foam containing 30 to 95% by weight of a polyolefin-based resin and 5 to 70% by weight of a hydrophilizing agent composed of a cellulose-based powder, the surface of the foam being in a melt fractured state. |
| US08772362B1 |
Expanded polystyrene made using D-limonene as a plasticizer
Disclosed is a process for production of expanded polystyrene using D-limonene as a plasticizer, which allows reducing the amount of pentane in the process, yet allows generating beads with similar cell size as if greater quantities of pentane had been used. Pentane is an organic solvent with toxicity associated with organic solvents. |
| US08772361B2 |
Process for producing a purified synthesis gas stream
A process for producing a purified synthesis gas stream from a feed synthesis gas stream comprising besides the main constituents carbon monoxide and hydrogen also hydrogen sulphide, HCN and/or COS, the process comprising the steps of: (a) contacting one part of the feed synthesis gas stream with a water gas shift catalyst in a shift reactor in the presence of water and/or steam to react at least part of the carbon monoxide to hydrogen and carbon dioxide, to obtain a shifted synthesis gas stream enriched in hydrogen and in carbon dioxide; (b) contacting another part of the feed gas stream with a hydrolysis catalyst in the presence of water to remove HCN and/or COS to obtain a hydrolysed synthesis gas stream depleted in HCN and/or COS; (c) removing H2S from the shifted synthesis gas stream and from the hydrolysed synthesis gas stream by contacting these gas streams in a H2S-removal zone with an aqueous alkaline washing liquid to obtain a H2S-depleted synthesis gas stream and a sulphide-comprising aqueous stream; (d) contacting the sulphide-comprising aqueous stream with sulphide-oxidizing bacteria in the presence of oxygen in a bioreactor to obtain a sulphur slurry and aregenerated aqueous alkaline washing liquid; (e) removing carbon dioxide from the H2S-depleted synthesis gas stream, to obtain the purified synthesis gas stream. |
| US08772358B2 |
Lecithin and plasticizer compositions and methods
The present invention is directed towards compositions having lecithin and a plasticizer. Processes for producing such compositions are further disclosed. The present invention is also directed towards uses of the novel compositions as a dispersant in order to disperse compounds, such as in the fields of coatings, inks, cosmetics and the like. In one embodiment, the dispersants of the present invention are used to disperse pigments. |
| US08772349B2 |
Cannabinoid quinone derivatives
Cannabinoid quinone derivatives. The present invention refers to cannabinoid quinone derivatives to be used as medicaments, particularly as PPAR gamma (PPARg) agonists for treating diseases which etiology is based on an impaired PPARg function as transcription factor i.e. PPARg-related diseases. |
| US08772348B2 |
Materials and methods for pest control
The present invention provides a novel insecticide formulation that not only demonstrates strong insecticidal and residual activity against a variety of insects, but also exhibits low mammalian toxicity. In certain embodiments, the present invention relates to the use of pesticidal compounds selected from beta damascone, CYCLEMONE A™, melafleur, and derivatives thereof for killing arthropod pests including, but not limited to, mosquitoes and flies. Specifically exemplified herein is the use of the compounds of the present invention to control three mosquitoes (Aedes aegypti, Ae. albopictus, and Anopheles quadrimaculatus), the house fly (Musca domestica), the stable fly (Stomoxys calcitrans) and the sand fly (Lutzomyia shannoni). |
| US08772344B2 |
Pharmaceutical composition for inhibiting osteoclast growth
A pharmaceutical composition for inhibiting osteoclast growth is disclosed in the present invention. The pharmaceutical composition includes a compound represented by a formula (I), and a pharmaceutically acceptable salt and carrier: wherein R1, R2, R3, R4 can be one selected from a group consisting of hydrogen, halogen, C1˜C10 alkyl group, C2˜C10 alkynyl group, amino group, haloalkyl group and sulfonamide group. |
| US08772342B2 |
Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
The invention provides 1,3-diphenylprop-2-en-1-one derivatives and pharmaceutical compositions comprising the same for treating liver disorders, in particular those requiring the reduction of plasma level of biochemical markers such as aminotransferases. The 1,3-diphenylprop-2-en-1-one derivatives of General Formula (I) have hepatoprotective properties and can be used in methods for treating liver disorders involving the pathological disruption, inflammation, degeneration, and/or proliferation of liver cells, such as liver fibrosis or fatty liver disease. |
| US08772340B2 |
Process for the preparation of fesoterodine or a salt thereof
A process for the preparation of (R)-2-(3-diisopropylamino-1-phenylpropyl)-4-(hydroxymethyl)-phenol isobutyrate (Fesoterodine) or a pharmaceutically acceptable salt thereof having low content in impurities. |
| US08772333B2 |
Fumigillol type compounds and methods of making and using same
The disclosure provides a fumagillol type compound and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of using, e.g. in the treatment of obesity are provided. |
| US08772327B2 |
Phenylpropionic acid derivative and use thereof
A compound represented by the following general formula (1) or a salt thereof, which has superior inhibitory activity against type 4 PLA2, and thus has prostaglandin and/or leucotriene production suppressing action [X represents a halogen atom, an alkyl group which may be substituted, or the like, Y represents hydrogen atom or an alkyl group which may be substituted, and Z represents hydrogen atom or an alkyl group which may be substituted]. |
| US08772322B2 |
Synergistic preservative compositions
A preservative composition comprising: (a) 1,2-Benzisothiazolin-3-one (BIT); (b) 3-Iodo-2-propynyl carbamate (IPBC); and (c) a mixture of 5-Chloro-2-methyl-4-isothiazolin-3-one (CMIT) and 2-Methyl-4-isothiazolm-3-one (MIT). |
| US08772319B2 |
Diagnostic and therapeutic alkyl piperidine/piperazine compounds and process
Described herein are piperidine and piperazine compounds useful for treating neurodegenerated diseases characterized by a lack of dopamine neuron activity. The compounds are also useful for imaging dopamine neurons. |
| US08772318B2 |
Methods and compositions related to targeting monoacylglycerol lipase
This invention provides compounds that selectively inhibit monoacylglycerol lipase (MAGL). The invention also provides methods of using the MAGL selective inhibitors to stimulate 2-Arachidonoylglycerol (2-AG) mediated endocannabinoid signaling in vivo, and to treat conditions that are associated with or linked to endocannabinoid signaling. The invention additionally provides methods of treating cancer or inhibiting tumor growth by targeting MAGL with MAGL specific inhibitors. The invention further provides methods of screening for MAGL inhibitors with improved biochemical and pharmaceutical properties. |
| US08772308B2 |
Non-peptidyl, potent, and selective mu opioid receptor antagonists
Selective, non-peptide antagonists of the mu opioid receptor (MOR) and methods of their use are provided. The antagonists may be used, for example, to identify MOR agonists in competitive binding assays, and to treat conditions related to addiction in which MOR is involved, e.g. heroin, prescription drug and alcohol addiction. |
| US08772302B2 |
GPR 119 agonists
The present invention relates to novel GPR 119 agonists of the general Formula (I), their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, enantiomers, stereoisomers, and polymorphs. The invention also relates to processes for the preparation of the compounds of the invention, pharmaceutical compositions containing the compounds and to methods for treating one or both of diabetes and obesity using the compounds of the invention. The present invention is directed to G-protein coupled receptor (GPCR) agonists that are useful for the treatment of obesity, diabetes and related metabolic disorders. |
| US08772296B2 |
Benzamide derivatives and uses related thereto
Benzamide derivatives of formula I are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders: wherein R1, R2, R3, R4, R5, R6, R7, R8, and n are as defined herein. |
| US08772287B2 |
Pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer therapy
Provided herein are pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides, e.g., compounds of Formulae IA, IB, and IC, and their pharmaceutical compositions, preparation, and use as agents or drugs for cancer therapy, either alone or in combination with radiation and/or other anticancer drugs. |
| US08772286B2 |
MK2 inhibitors
The present invention relates to compounds of general Formula (I) or a pharmaceutically acceptable salt thereof. The compounds can be used in the treatment of immune, autoimmune, inflammatory diseases, cardiovascular diseases, infectious diseases, bone resorption disorders, neurodegenerative diseases or proliferative diseases. |
| US08772282B2 |
Tetrahydropyrrolothiazine compounds
The present invention provides compounds of Formula I: wherein A is selected from the group consisting of; R1 is H or F; R2 is H, —CH2OH, C1-C3 alkyl, R3 is H, F, or CN; R4 is H, F; or CN; and R5 is H, —CH3, or —OCH3; or a pharmaceutically acceptable salt thereof. |
| US08772280B2 |
N-aryl-2-(2-arylaminopyrimidin-4-yl)pyrrol-4-carboxamide derivatives as MPS1 kinase inhibitors
The present invention relates to substituted pyrrolyl-pyrimidines which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular MPS1. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such these compounds or the pharmaceutical compositions containing them. |
| US08772275B2 |
Mediators of hedgehog signaling pathways, compositions and uses related thereto
The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity. |
| US08772274B1 |
Anti-cancer compositions and methods
Anti-cancer compositions and methods are described including one or more compounds having the structural formula I: R2-R—R1, where R is phenyl, where R1 is (CH2)n—Se—C(═NH)—NH2, where R2 is (CH2)n—Se—C(═NH)—NH2 or R2 is H, and where each n is independently 2, 3, 4, 5, 6, 7, or 8. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including one or more compounds having the structural formula I to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including one or more compounds having the structural formula I to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation. Compositions of the present invention inhibit Akt enzymes, iNOS, and increase MAP kinase activity such that cancer cells contacted with the compositions are inhibited. |
| US08772265B2 |
Water soluble curcumin compositions for use in anti-cancer and anti-inflammatory therapy
The present invention relates to the medical field. In a first aspect the present invention relates to novel water soluble cyclodextrin-curcumin complexes having a pharmacological activity, in particular an anti-tumor and/or anti-inflammatory activity, and improved physico-chemical properties. In a second aspect, the present invention relates to a method for preparation of said water soluble curcumin derivatives. The invention further relates in a third aspect to a pharmaceutical composition comprising an effective amount of said water soluble curcumin derivatives. In a fourth aspect, the present invention concerns the use of said water soluble cucumin derivatives as a medicament and the use of said water soluble curcumin derivatives for the preparation of a medicament for the treatment of cancer and inflammatory diseases. In a fifth aspect, the present invention relates to the use of a pharmaceutical composition comprising said water soluble curcumin derivatives in the treatment of cancer and inflammatory diseases and to a new pharmaceutical composition comprising said water soluble curcumin derivatives. |
| US08772264B2 |
Methods of treating hematologic cancers
This disclosure relates to the treatment of hematologic cancers, for example, cancers of the blood, by methods that include administration of EGCG and at least one of a purine nucleoside analog and an alkylating agent. In particular, methods of treating chronic lymphocytic leukemia (CLL) and acute lymphocytic leukemia (ALL) are described. |
| US08772261B2 |
Treatment of tumors with genetically engineered herpes virus
Disclosed are methods for treating cancer by administering an effective amount of a modified Herpes simplex virus. |
| US08772257B2 |
SDF-1 binding nucleic acids and the use thereof
The present invention is related to a nucleic acid molecule binding to SDF-1, whereby the nucleic acid molecule influences migration of cells. |
| US08772254B2 |
Method and constructs for delivering double stranded RNA to pest organisms
The present invention relates in generally to RNAi and its use in gene silencing. In particular, the present invention relates to methods and constructs for delivering double stranded RNA (dsRNA) to pest organisms. |
| US08772253B2 |
Aureolic acid derivatives, the method for preparation thereof and the uses
Aureolic acid derivatives, process for obtaining them and uses thereof. This invention provides a bacterial strain that produces compound belonging to the family of aureolic acids useful in the treatment of cancer or nervous system diseases. |
| US08772243B2 |
Methods for predicting the response to anti-cancer treatment with an agonist of TLR7 or an agonist of TLR8
The present invention relates to methods for predicting the response to treatment with an agonist of TLR7, or an agonist of TLR8 or an anti-cancer agent for treating cancer, in particular non-small cell lung cancer comprising the step of detecting the expression of TLR7 or TLR8 in cancer cells of said patient. |
| US08772242B2 |
Therapy for enteric infections
There is disclosed herein a composition for treating gastrointestinal or neurological disorders, constipation, functional constipation, irritable bowel syndrome, diverticulitis, travelers diarrhea, chronic idiopathic nausea, IBD-associated constipation and diarrhea, pseudo-obstruction, diabetic gastroparesis, cyclic vomiting, reflux oesophagitis, autism enteropathy, flatulence, halitosis, chronic fatigue, bloating, proctalgia fugax, Parkinsons disease, MS, Alzheimers Disease, Motor Neurone Disease or autism, the composition comprising: (i) at least two anti-clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide, colchicine, prucalopride, prokinetic agent and 5-aminosalicylic acid; or (ii) at least one anti-clostridial agent selected from the above combined with an opioid blocking agent. There is also disclosed herein a method of treating various gastrointestinal or neurological disorders, constipation, functional constipation, irritable bowel syndrome, diverticulitis, travelers diarrhea, chronic idiopathic nausea, IBD-associated constipation and diarrhea, pseudo-obstruction, diabetic gastroparesis, cyclic vomiting, reflux oesophagitis, autism enteropathy, flatulence, halitosis, chronic fatigue, bloating, proctalgia fugax, Parkinsons disease, MS, Alzheimers Disease, Motor Neurone Disease or autism, the method comprising administering orally, via enema or by suppository: (i) a composition of the invention; (ii) at least two anti-clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide, colchicine, prucalopride, prokinetic agent and 5-aminosalicylic acid; or (iii) at least one anti-clostridial agent selected from the above and an opioid blocking agent to a patient in need of such treatment. |
| US08772236B2 |
Truncated cystine-knot proteins
The invention relates to the fields of protein chemistry, biology and medicine. More specifically, it relates to the design and preparation of proteinmimics of members of the cystine-knot growth factor superfamily. Further, the invention relates to the use of these proteinmimics as a medicament or prophylactic agent. The invention provides proteinmimics of members of the cystine-knot growth factor superfamily, preferably for use in immunogenic and/or therapeutic compositions. |
| US08772234B2 |
BMP10 propeptides and related methods
In certain aspects, the present invention provides BMP10 propeptides for use in treating a variety of disorders including heart disorders and other disorders associated with unwanted activity of the mature BMP10 polypeptide. The present invention also provides methods of screening compounds that modulate activity of BMP10. |
| US08772228B2 |
Aligned nanofibers and related methods of use
The present invention relates to nanofibers. In particular, the present invention provides aligned nanofiber bundle assemblies. In some embodiments, the aligned nanofiber bundle assemblies are used for tissue regeneration, controlled growth of cells, and related methods (e.g., diagnostic methods, research methods, drug screening). |
| US08772218B2 |
Stain-discharging and removing system
A cleaning composition that can discharge the color of blood, menstrual fluids, or other organic stains is provided. In particular, the present invention achieves a balance between control of unwanted liquid spreading by lateral wicking on a stained textile fabric to lessen the size of wet spots and maintaining the cleaning efficacy of the composition by means of specific kinds of thickening agents. The composition includes an oxidizing agent such as peroxides, a cell-lysing agent, a chelating agent, an antioxidant, a thickener, and other optional ingredients that are selectively employed to achieve an aqueous based composition that exhibits good shelf stability and stain removal properties. The thickening agent may include a cellulosic or clay material, starch, gum, fatty acid, fatty alcohol, hydrophilic colloidal particles, polyoxyethylene glycol or polyoxyethylene glycol derivatives including fatty acid esters and ethers, or a combination thereof. |
| US08772216B2 |
Low VOC hard surface cleaning composition comprising a glycol ether solvent
The present invention relates to a low VOC hard surface cleaning composition comprising a surfactant, a glycol ether organic solvent, an aminoalcohol and fragrance, having a pH from 10.0 to 12.0. The present invention further encompasses a process to prepare a low VOC hard surface cleaning composition. Furthermore, the present invention encompasses a process of cleaning a hard surface with a low VOC hard surface cleaning composition. |
| US08772214B2 |
Aqueous cleaning composition for removing residues and method using same
A composition and method for removing residues such as, without limitation, post etched and/or post ashed photoresist, plasma etching, ashing, and mixtures thereof from a substrate is described herein. In one aspect, there is provided a method for removing residues from a substrate comprising: contacting the substrate with a composition comprising: water; a quaternary ammonium hydroxide compound; a fluoride containing compound; and optionally a corrosion inhibitor wherein the composition is free of an added organic solvent and wherein the composition has a pH greater than 9. |
| US08772213B2 |
Solvent compositions including trans-1-chloro-3,3,3-trifluoropropene and uses thereof
The present invention relates to solvent compositions including an effective amount of 1-chloro-3,3,3-trifluoropropene and uses thereof. In certain aspects, such solvent compositions may be applied to the surface of an article or portion of an article having an ink or ink-based marking so as to remove the ink or ink-based marking without deleteriously impacting the article or surface of the article. |
| US08772206B2 |
Treatment fluids made of halogenisocyanuric acid and its salts for operations in a well
The invention discloses a method comprising providing a fluid comprising a viscosifying agent in an aqueous medium; contacting the fluid with a halogenisocyanuric acid or halogenisocyanurate component; whereby the viscosity of the fluid with the halogenisocyanuric acid or halogenisocyanurate component is reduced compared to the viscosity of the fluid alone; and introducing the fluid into a well. The halogenisocyanuric acid component can be mono chloroisocyanuric acid, dichloroisocyanuric acid or trichloroisocyanuric acid. The halogenisocyanurate component can be an alkali metal monochloroisocyanurate, alkali metal dichloroisocyanurate or alkali metal trichloroisocyanurate. |
| US08772202B2 |
Articles having localized molecules disposed thereon and methods of producing same
Methods of producing substrates having selected active chemical regions by employing elements of the substrates in assisting the localization of active chemical groups in desired regions of the substrate. The methods may include optical, chemical and/or mechanical processes for the deposition, removal, activation and/or deactivation of chemical groups in selected regions of the substrate to provide selective active regions of the substrate. |
| US08772194B2 |
Method for preparing large-sized titanium-silicalite molecular sieve and method for preparing cyclohexanone oxime using the molecular sieve
The present invention provides a method for preparing a large-sized titanium-silicalite molecular sieve, and a method for preparing cyclohexanone oxime using the large-sized titanium-silicalite molecular sieve. The method for preparing a large-sized titanium-silicalite molecular sieve includes preparing a mixture of a titanium source, a silicon source and a template agent; heating the mixture to form a gel mixture; mixing a colloidal silica with the gel mixture; heating the gel mixture mixed with the colloidal silica in a water bath; and calcining the gel mixture mixed with the colloidal silica. In the present invention, the average particle size of the large-sized titanium-silicalitem molecular sieve is more than 10 um, and the particle size distribution is centralized, so as to avoid the formation of titanium-oxygen-titanium bonding. The method for preparing cyclohexanone oxime using the large-sized titanium-silicalite molecular sieve results in high conversion rate, high selectivity and easy recovery. |
| US08772193B2 |
Catalyst for a hydrogenation dewaxing process and method for manufacturing same
The present invention relates to a bifunctional catalyst for a hydrodewaxing process with improved isomerization selectivity, and to a method for manufacturing the same, and more particularly to a bifunctional catalyst and to a method for manufacturing same, which is characterized in that EU-2 zeolite with a controlled degree of phase transformation is used as a catalyst support having an acid site. The EU-2 zeolite, the degree of phase transformation of which is controlled, includes, by controlling synthesis parameters of EU-2, predetermined amounts of materials that are phase-transformed from EU-2 crystals such as cristobalite and quartz. The metal loaded bifunctional catalyst according to the present invention improves selectivity of the isomerization process, rather than a cracking reaction, during a hydroisomerization reaction of n-hexadecane. Therefore, the bifunctional catalyst can be widely used as a catalyst for a dewaxing process such as lubricant base oil and diesel oil. |
| US08772191B2 |
Process for the off site regeneration of solid catalysts
The invention provides a process for the off site regeneration of a solid catalyst, comprising two consecutive steps: a first step of washing the catalyst using one or more fluid(s) in the supercritical state, so as to extract from the catalyst at least a portion of the hydrocarbons present at the surface of the latter, followed by a second step of combustion of at least a portion of the coke present at the surface of the said catalyst by a heat treatment of the latter in the presence of oxygen and at a temperature ranging from 300° C. to 600° C. |
| US08772178B2 |
Technique for forming a dielectric interlayer above a structure including closely spaced lines
By depositing the lower portion of a silicon dioxide interlayer dielectric by means of SACVD or HDP-CVD techniques, the generation of voids may be reliably avoided even for devices having spaces between closely spaced lines on the order of 200 nm or less. Moreover, the bulk silicon dioxide material is deposited by well-established plasma enhanced CVD techniques, thereby providing the potential for using well-established process recipes for the subsequent CMP process, so that production yield and cost of ownership may be maintained at a low level. |
| US08772177B2 |
Semiconductor wafer and method of producing the same
A wafer surface of a semiconductor wafer to be used as a device active region is mirror-polished, and an outer peripheral portion of the mirror-polished wafer surface is further polished, thereby forming an edge roll-off region between the device active region of the wafer surface and a beveled portion formed at the wafer edge. The edge roll-off region has a specific roll-off shape corresponding to an edge roll-off of the oxide film to be formed in a device fabrication process. Thus, a semiconductor wafer can be provided in which reduction in the thickness of an oxide film on the outer peripheral portion of the wafer in a CMP process can be prevented while maintaining high flatness of the wafer surface. |
| US08772176B2 |
Method for forming an adhesive layer and adhesive composition
In a forming method of an adhesive layer including the steps of selectively coating, on a surface to be bonded, an adhesive composition containing a thermosetting composition and an organic solvent using a noncontact coating device; and removing the organic solvent from the adhesive composition coated on the surface to be bonded and in a forming method of an adhesive layer characterized in the thermosetting composition has a hardening property so as to exhibit two kinds of reaction temperatures, the adhesive composition comprising an epoxy resin and an epoxy curing agent which are reacted through a first hardening reaction exhibiting a first DSC peak within a temperature range of 100 to 160° C. and a second hardening reaction relating to a self-polymerization of the epoxy resin and exhibiting a second DSC peak within a temperature range of 140 to 200° C. |
| US08772175B2 |
Method for manufacturing semiconductor device and semiconductor device
A CMOS SGT manufacturing method includes a step of forming first and second fin-shaped silicon layers on a substrate, forming a first insulating film around the first and second fin-shaped silicon layers, and forming first and second pillar-shaped silicon layers; a step of forming n-type diffusion layers; a step of forming p-type diffusion layers; a step of forming a gate insulating film and first and second polysilicon gate electrodes; a step of forming a silicide in upper portions of the diffusion layers in upper portions of the first and second fin-shaped silicon layers; and a step of depositing an interlayer insulating film, exposing the first and second polysilicon gate electrodes, etching the first and second polysilicon gate electrodes, and then depositing a metal to form first and second metal gate electrodes. |
| US08772168B2 |
Formation of the dielectric cap layer for a replacement gate structure
Gate to contact shorts are reduced by forming dielectric caps in replaced gate structures. Embodiments include forming a replaced gate structure on a substrate, the replaced gate structure including an ILD having a cavity, a first metal on a top surface of the ILD and lining the cavity, and a second metal on the first metal and filling the cavity, planarizing the first and second metals, forming an oxide on the second metal, removing the oxide, recessing the first and second metals in the cavity, forming a recess, and filling the recess with a dielectric material. Embodiments further include dielectric caps having vertical sidewalls, a trapezoidal shape, a T-shape, or a Y-shape. |
| US08772161B2 |
Annealing copper interconnects
A method for modifying the chemistry or microstructure of silicon-based technology via an annealing process is provided. The method includes depositing a reactive material layer within a selected proximity to an interconnect, igniting the reactive material layer, and annealing the interconnect via heat transferred from the ignited reactive material layer. The method can also be implemented in connection with a silicide/silicon interface as well as a zone of silicon-based technology. |
| US08772154B2 |
Integrated circuits including barrier polish stop layers and methods for the manufacture thereof
Embodiments of a method for fabricating integrated circuits are provided, as are embodiments of an integrated circuit. In one embodiment, the method includes the steps of depositing an interlayer dielectric (“ILD”) layer over a semiconductor device, depositing a barrier polish stop layer over the ILD layer, and patterning at least the barrier polish stop layer and the ILD layer to create a plurality of etch features therein. Copper is plated over the barrier polish stop layer and into the plurality of etch features to produce a copper overburden overlying the barrier polish stop layer and a plurality of conductive interconnect features in the ILD layer and barrier polish stop layer. The integrated circuit is polished to remove the copper overburden and expose the barrier polish stop layer. |
| US08772149B2 |
FinFET structure and method to adjust threshold voltage in a FinFET structure
FinFET structures and methods of manufacturing the FinFET structures are disclosed. The method includes performing an oxygen anneal process on a gate stack of a FinFET structure to induce Vt shift. The oxygen anneal process is performed after sidewall pull down and post silicide. |
| US08772148B1 |
Metal gate transistors and fabrication method thereof
A method is provided for fabricating a metal gate transistor. The method includes providing a semiconductor substrate; and forming a dielectric layer on the semiconductor substrate. The method also includes forming at least one dummy gate on the dielectric layer; and forming a first sidewall spacer around the dummy gate. Further, the method includes forming a gate dielectric layer with sidewalls protruding from sidewalls of the dummy gate and vertical to the semiconductor substrate by etching the dielectric layer using the first sidewall spacer and the dummy gate as an etching mask; and removing the dummy gate to form a trench. Further, the method also includes forming a metal gate in the trench; and forming a source region and a drain region in the semiconductor substrate. |
| US08772146B2 |
Semiconductor device and method for fabricating the same
A method of fabricating a semiconductor device includes forming a first gate pattern and a dummy gate pattern on a first active area and a second active area of a substrate, respectively, the first gate pattern including a first gate insulating layer and a silicon gate electrode, removing the dummy gate pattern to expose a surface of the substrate in the second active area, forming a second gate pattern including a second gate insulating layer and a metal gate electrode on the exposed surface of the substrate, the first gate insulating layer having a thickness larger than a thickness of the second gate insulating layer, and forming a gate silicide on the silicon gate electrode after forming the second gate pattern. |
| US08772145B2 |
Carbon nanotube dispersion liquid and method of manufacturing thin layer and display panel using the same
The present invention relates to a carbon nanotube dispersion liquid includes carbon nanotubes, a self assembly material having —NR2 in one terminal thereof and —Si(OR)3 or —SH in the other terminal thereof, and a solvent, as well as its usage. |
| US08772143B2 |
Field effect transistor devices with dopant free channels and back gates
A method of forming a back gate transistor device includes forming an open isolation trench in a substrate; forming sidewall spacers in the open isolation trench; and using the open isolation trench to perform a doping operation so as to define a doped well region below a bottom surface of the isolation trench that serves as a back gate conductor, wherein the sidewall spacers prevent contamination of a channel region of the back gate transistor device by dopants. |
| US08772140B2 |
Production method for a unipolar semiconductor component and semiconductor device
A unipolar semiconductor component having a drift layer is produced by forming the drift layer with a continuously decreasing concentration of a charge carrier doping along the growth direction of the drift layer by way of epitaxial precipitation of the material of the drift layer, which comprises at least one wide band gap material. By using silicon carbide for the drift layer formed by the epitaxial precipitation, a subsequent change of the continuously decreasing concentration of the charge carrier doping due to a diffusion of the dopant atoms in downstream processes is suppressed. The production method can be used in particular to implement a unipolar semiconductor component comprising a drift layer, which component has an advantageous ratio of a comparatively high reverse bias voltage with relatively low forward losses, in a simple and/or cost-effective manner. The unipolar semiconductor component can be an active or passive semiconductor component. |
| US08772137B2 |
Semiconductor wafer with assisting dicing structure and dicing method thereof
A semiconductor wafer with an assisting dicing structure. The wafer comprises a substrate having a front surface and a rear surface. The front surface of the substrate comprises at least two device regions separated by at least one dicing lane. The rear surface of the substrate comprises at least one pre-dicing trench formed therein and substantially aligned with the dicing lane. A method for dicing a semiconductor wafer is also disclosed. |
| US08772135B2 |
Semiconductor device manufacturing method using laser irradiation and dicing saw and semiconductor device thereof
To divide a semiconductor wafer by stealth dicing, a test pad in a cutting region and an alignment target are collectively arranged along one side in a width direction of the cutting region, and a laser beam for forming a modified region is irradiated to a position away in plane from the test pad and the alignment target Am. In this manner, defects in cutting shape in a cutting process of a semiconductor wafer using stealth dicing can be reduced or prevented. |
| US08772133B2 |
Utilization of a metallization scheme as an etching mask
The various aspects comprise methods and devices for processing a wafer.An aspect of this disclosure includes a wafer. The wafer comprises a plurality of die regions; a plurality of kerf regions between the plurality of die regions; and a metallization area on the plurality of die regions. |
| US08772131B2 |
Method for bonding semiconductor substrates
A method is provided for bonding a first substrate carrying a semiconductor device layer on its front surface to a second substrate. The method comprises producing the semiconductor device layer on the front surface of the first substrate, depositing a first metal bonding layer or a stack of metal layers on the first substrate, on top of the semiconductor device layer, depositing a second metal bonding layer or a stack of metal layers on the front surface of the second substrate, depositing a metal stress-compensation layer on the back side of the second substrate, thereafter establishing a metal bond between the first and second substrate, by bringing the first and second metal bonding layers or stacks of layers into mutual contact under conditions of mechanical pressure and temperature suitable for obtaining the metal bond, and removing the first substrate. |
| US08772128B2 |
Method for manufacturing semiconductor device
A single crystal semiconductor substrate is irradiated with ions that are generated by exciting a hydrogen gas and are accelerated with an ion doping apparatus, thereby forming a damaged region that contains a large amount of hydrogen. After the single crystal semiconductor substrate and a supporting substrate are bonded, the single crystal semiconductor substrate is heated to be separated along the damaged region. While a single crystal semiconductor layer separated from the single crystal semiconductor substrate is heated, this single crystal semiconductor layer is irradiated with a laser beam. The single crystal semiconductor layer undergoes re-single-crystallization by being melted through laser beam irradiation, thereby recovering its crystallinity and planarizing the surface of the single crystal semiconductor layer. |
| US08772126B2 |
Method of manufacturing a semiconductor device including grinding from a back surface and semiconductor device
A cavity is etched from a front surface into a semiconductor substrate. After providing an etch stop structure at the bottom of the cavity, the cavity is closed. From a back surface opposite to the front surface the semiconductor substrate is grinded at least up to an edge of the etch stop structure oriented to the back surface. Providing the etch stop structure at the bottom of an etched cavity allows for precisely adjusting a thickness of a semiconductor body of a semiconductor device. |
| US08772124B2 |
Full wafer processing by multiple passes through a combinatorial reactor
Overlapping combinatorial processing can offer more processed regions, better particle performance and simpler process equipment. In overlapping combinatorial processing, one or more regions are processed in series with some degrees of overlapping between regions. In some embodiments, overlapping combinatorial processing can be used in conjunction with non-overlapping combinatorial processing and non-combinatorial processing to develop and investigate materials and processes for device processing and manufacturing. |
| US08772122B2 |
Programmable metallization memory cell with layered solid electrolyte structure
Programmable metallization memory cells having an active electrode, an opposing inert electrode and a variable resistive element separating the active electrode from the inert electrode. The variable resistive element includes a plurality of alternating solid electrolyte layers and electrically conductive layers. The electrically conductive layers electrically couple the active electrode to the inert electrode in a programmable metallization memory cell. Methods to form the same are also disclosed. |
| US08772113B2 |
Method for manufacturing silicon carbide semiconductor device
A silicon carbide substrate is prepared which has a main surface covered with a silicon dioxide layer. In the silicon dioxide layer, an opening is formed by etching. In the opening, a residue resulting from the etching is on the silicon carbide substrate. The residue is removed by plasma etching in which only an inert gas is introduced. After removing the residue, under heating, a reactive gas is supplied to the silicon carbide substrate covered with the silicon dioxide layer having the opening formed therein. In this way, a trench is formed in the main surface of the silicon carbide substrate. |
| US08772108B1 |
Multi-time programmable non-volatile memory
A process for creating a low-cost multi-time programmable (MTP) non-volatile memory (NVM) and the resulting device are provided. Embodiments include forming a select gate and a floating gate above a substrate, each over a first shallow trench isolation (STI) region, a doped region formed between a source and a drain, and a second STI region, forming a metal layer over the floating gate, and forming a pair of self-aligned contacts on the first and second STI regions on opposite sides of the doped region, respectively, and electrically connected to the metal layer. |
| US08772105B2 |
Semiconductor device and method for forming the same
A semiconductor device and a method for forming the same are disclosed. The semiconductor device includes a first junction region formed at the bottom of a vertical pillar, a bit line formed below the first junction region, and an insulation film formed below the bit line. As a result, the 4F2-sized semiconductor device is provided and the bit line is configured in the form of a laminated structure of a conductive layer and a polysilicon layer, so that bit line resistance is reduced. In addition, the semiconductor device reduces ohmic contact resistance by forming silicide between the conductive layer and the polysilicon layer, and includes an insulation film at a position between the semiconductor substrate and the bit line, resulting in reduction of bit line capacitance. Therefore, the sensing margin of the semiconductor device is increased and the data retention time is also increased. |
| US08772104B2 |
Capacitor and method for fabricating the same, and semiconductor device and method for fabricating the same
The semiconductor device comprises a device isolation region formed in a semiconductor substrate, a lower electrode formed in a device region defined by the device isolation region and formed of an impurity diffused layer, a dielectric film of a thermal oxide film formed on the lower electrode, an upper electrode formed on the dielectric film, an insulation layer formed on the semiconductor substrate, covering the upper electrode, a first conductor plug buried in a first contact hole formed down to the lower electrode, and a second conductor plug buried in a second contact hole formed down to the upper electrode, the upper electrode being not formed in the device isolation region. The upper electrode is not formed in the device isolation region, whereby the short-circuit between the upper electrode and the lower electrode in the cavity can be prevented. |
| US08772095B2 |
Method of manufacturing semiconductor device using stress memorization technique
The manufacturing a semiconductor device includes providing a substrate supporting a gate electrode, amorphizing and doping the source/drain regions located on both sides of the gate electrode by performing a pre-amorphization implant (PAI) process and implanting C or N into the source/drain regions in or separately from the PAI process, forming a stress inducing layer on the substrate to cover the amorphized source/drain regions, and subsequently recrystallizing the source/drain regions by annealing the substrate. The stress inducing layer may then be removed. Also, the C or N may be implanted into the entirety of the source/drain regions after the regions have been amorphized, or only into upper portions of the amorphized source/drain regions. |
| US08772088B2 |
Method of manufacturing high frequency module and high frequency module
In a high frequency module, electronic components are mounted on a mounting surface of a collective substrate including a plurality of unit substrates that include a via conductor electrically conducted to a ground potential in a peripheral portion thereof, and the mounting surface and the electronic components are encapsulated with an encapsulation layer. The collective substrate is cut on the encapsulation layer side, thereby forming a half-cut groove penetrating through the encapsulation layer and extending halfway along the collective substrate in a thickness direction such that the via conductor is exposed only at a bottom surface of the half-cut groove. A conductive shield layer is formed to cover the encapsulation layer and is electrically conducted to the exposed via conductor. The collective substrate is then cut into individual unit substrates each including the conductive shield layer electrically conducted to the ground potential through the via conductor. |
| US08772085B2 |
Integrated circuit package architecture
A packaging architecture for an integrated circuit is provided. The architecture includes a printed circuit board and a package substrate disposed on the printed circuit board. A first integrated circuit is disposed on a first surface of the package substrate. The package substrate is capable of supporting a second integrated circuit. The second integrated circuit is in electrical communication with a plurality of pads disposed on the first surface of the package substrate. Each of the plurality of pads is in electrical communication with the printed circuit board without communicating with the first integrated circuit. |
| US08772084B2 |
Multi-chip semiconductor package and method of fabricating the same
A first semiconductor chip having a first projection electrode formed on an upper surface thereof is prepared. A second semiconductor chip having a second projection electrode is mounted on the first semiconductor chip to expose the first projection electrode. An insulating film is formed between the first projection electrode and the second projection electrode. A groove is formed in the insulating film. An interconnection configured to fill an inside of the groove and connected to the first projection electrode and the second projection electrode is formed. |
| US08772082B2 |
Light-emitting element and light-emitting device
To provide a light-emitting element, a light-emitting device, and an electronic device each formed using the organometallic complex represented by General Formula (G1) as a guest material and a low molecule compound as a host material. |
| US08772079B2 |
Backside contacting on thin layer photovoltaic cells
A method of backside contacting of thin layer photovoltaic cells having Si elements as well as thin film cells, like CIGS, is provided, including the following steps: providing a p-n-junction including a thin n-doped Si layer and a thin p-doped Si layer bonded on top of said n-doped Si layer; bonding said p-n-junction to a glass substrate; preparing contact points on said structured thin p-doped Si layer and said thin n-doped Si layer; and creating contact pins on said structured thin p-doped Si layer and said thin n-doped Si layer. |
| US08772077B2 |
Method of forming chalcogenide thin film
The present invention concerns a method of forming a chalcogenide thin film for a phase-change memory. In the method of forming a chalcogenide thin film according to the present invention, a substrate with a pattern formed is loaded into a reactor, and a source gas is supplied onto the substrate. Here, the source gas includes at least one source gas selected from germanium (Ge) source gas, gallium (Ga) source gas, indium (In) source gas, selenium (Se) source gas, antimony (Sb) source gas, tellurium (Te) source gas, tin (Sn) source gas, silver (Ag) source gas, and sulfur (S) source gas. A first purge gas is supplied onto the substrate in order to purge the source gas supplied onto the substrate, a reaction gas for reducing the source gas is then supplied onto the substrate, and a second purge gas is supplied onto the substrate in order to purge the reaction gas supplied onto the substrate. At least one operation, namely changing the supply time of the first purge gas and/or adjusting the internal pressure of the reactor is performed in such a way as to ensure that the deposition rate at an inner portion of the pattern is greater than the deposition rate at an upper portion of the pattern. According to the present invention, it is possible to form a chalcogenide thin film having an excellent gap-fill property by changing the purge time of the source gas or adjusting the internal pressure of the reactor in such a way as to ensure that the film forming rate at the inner portion of the pattern is greater than the film forming rate at the upper portion of the pattern. |
| US08772070B2 |
Method for manufacturing solid-state imaging device
A method for manufacturing solid-state imaging device for collectively manufacturing a multiplicity of solid-state imaging devices at a wafer level, the method including: a step of reducing the thickness of a cover glass wafer (10) after providing a mask material (12) to the cover glass wafer (10) including frame-shaped spacers (5); a step of releasing the mask material (12) and laminating a first support wafer (14) through a lamination member (16); a step of positioning and bonding a silicon wafer (18) and the cover glass wafer (10), the silicon wafer (18) including a second support wafer (22) laminated on the back side through a lamination member (24); a step of dicing the cover glass wafer (10) into cover glasses (4) by a whetstone (26); and a step of dicing the silicon wafer (18) by a whetstone (28). |
| US08772065B2 |
Housing body and method for production thereof
A package body (1) with an upper side (2), with an underside (22), opposite from the upper side (2), and with a side surface, which connects the upper side (2) and the underside (22) and is provided as a mounting surface (19), the package body (1) having a plurality of layers (8) which contain a ceramic material, and a main direction of extent of the layers (23, 24, 25) running obliquely in relation to the mounting surface (19). Furthermore, a method for producing a package body (1) is provided. |
| US08772062B2 |
Method for manufacturing light emitting diode package having LED die fixed by anisotropic conductive paste
A method for packaging an LED, includes steps: providing a substrate and forming a plurality of pairs of electrodes on the substrate; positioning anisotropic conductive pastes on the substrate and attaching each anisotropic conductive paste to each pair of the electrodes; positioning an LED die on each anisotropic conductive paste and electrically connecting each LED die to each corresponding pair of the electrodes with the anisotropic conductive paste by hot compressing; forming an encapsulation on the substrate to cover the LED dies; and cutting the substrate to obtain individual LED packages. |
| US08772058B2 |
Method for making a redistributed wafer using transferrable redistribution layers
A method of making redistributed electronic devices that includes providing a wafer having a plurality of electronic devices, each electronic device having a pattern of contact areas forming die pads. The method also includes forming redistribution layers on a temporary substrate having a pattern of contact areas forming wafer bonding pads matching the die pads and a pattern of contact areas forming redistributed pads different than the wafer bonding pads, the wafer bonding pads are coupled to the redistributed pads through a plurality of stacked conductive and insulating layers. The die pads are coupled to the wafer bonding pads, and the temporary substrate is removed. The wafer and redistribution layers are then divided into a plurality of redistributed electronic devices. |
| US08772056B2 |
Dummy pattern design for thermal annealing
The present disclosure provides a semiconductor structure including a semiconductor substrate having a device region and a dummy region adjacent the device region; a plurality of active regions in the device region; and a plurality of dummy active regions in the dummy region, where each of the active regions has a first dimension in a first direction and a second dimension in a second direction perpendicular to the first direction, and the first dimension is substantially greater than the second dimension; and each of the dummy active regions has a third dimension in the first direction and a fourth dimension in the second direction, and the third dimension is substantially greater than the fourth dimension. The plurality of dummy active regions are configured such that thermal annealing effect in the dummy region is substantially equal to that of the device region. |
| US08772050B2 |
Zr-substituted BaTiO3 films
The use of a monolayer or partial monolayer sequencing process, such as atomic layer deposition (ALD), to form a zirconium substituted layer of barium titanium oxide, produces a reliable ferroelectric structure for use in a variety of electronic devices such as a dielectric in nonvolatile random access memories (NVRAM), tunable dielectrics for multi layer ceramic capacitors (MLCC), infrared sensors and electro-optic modulators. In various embodiments, structures can be formed by depositing alternating layers of barium titanate and barium zirconate by ALD on a substrate surface using precursor chemicals, and repeating to form a sequentially deposited interleaved structure of desired thickness and composition. The properties of the dielectric may be tuned by adjusting the percentage of zirconium to titanium to optimize properties such as a dielectric constant, Curie point, film polarization, ferroelectric property and a desired relaxor response. |
| US08772043B2 |
Universal peptide tags for transgene polypeptide analysis by mass spectrometry
Compositions and methods that allow for the rapid detection and accurate quantification of any polypeptides of interest are provided. Compositions include isolated polypeptides comprising at least one universal peptide tag, as well as isolated polynucleotides encoding such polypeptides. The universal peptide tags can be quantified by methods including, but not limited to, mass spectrometry, and can act as surrogates for determining the concentration of the polypeptides comprising the universal peptide tags. Methods provide for the detection and/or quantification of any polypeptides of interest that comprise at least one universal peptide tag, including methods using mass spectroscopy techniques. Methods are also provided for producing hosts, or cells or parts thereof, that comprise polypeptides comprising at least one universal peptide tag. Hosts, or cells, or parts thereof, include mammalian, bacterial, insect, yeast, viral or plant. |
| US08772041B2 |
Membrane precursors and membranes formed therefrom
Disclosed are biomimetic membrane precursors and membranes formed therefrom. Also disclosed are methods of making biomimetic membrane precursors and membranes formed therefrom. Methods of using, including methods of storing and handling biomimetic membrane precursors and membranes formed therefrom, are also disclosed. |
| US08772040B2 |
Apparatus and method of platelet multi-function analysis, and micro stirring chip
An apparatus and method for platelet multi-function analysis using measurement of electrical characteristics, and a stirring microchip are provided. The apparatus for platelet multi-function analysis includes a stirring microchip that has a sample storage chamber formed therein to hold a blood sample, and in which an inner part of the sample storage chamber is coated with reagents composed of collagen and epinephrine, or collagen and ADP. The apparatus for platelet multi-function analysis further includes a microstirrer installed inside the stirring microchip to stir the blood sample and the reagents in the stirring microchip and a stirring induction unit configured to facilitate stirring of the microstirrer. Therefore, the platelet aggregation and multi-function analysis can be performed using a trace of blood, and the platelet aggregation and multi-function analysis can also be performed using the whole blood taken from the veins through a vacuum tube containing an anticoagulant. |
| US08772039B2 |
Optical thromboelastography system and method for evaluation of blood coagulation metrics
Device, method, and computer program product for determining a material parameter of a blood coagulation cascade based on parameters of light diffused at a biofluid sample. In one example, the biofluid sample includes a blood sample. Laser light scattered by the sample is collected by the optical system in reflection and/or transmission mode. An image of the sample in so collected light is formed, and data representing fluctuations of laser speckle intensity with is processed to derive numerical descriptors associated with blood coagulation and fibrinolysis. In a specific case, such numerical descriptors are derived based on temporal dynamic of a viscoelastic characteristic of the blood sample. |
| US08772037B2 |
Analysis assisting method, analyzer, remote computer, data analyzing method, program, and reagent container
In an analysis system having an analysis apparatus using a reagent container having a memory to store reagent information concerning the reagent in the reagent container and a remote computer, the following steps are executed: reading out the reagent information from the memory of the reagent container; judging, based on the read reagent information, whether or not the reagent in the reagent container is usable; when it is judged that the reagent in the reagent container is unusable, writing data representing the reagent is unusable into the memory of the reagent container; and when it is judged that the reagent in the reagent container is unusable, registering the data representing the reagent is unusable, into a reagent database managed by the remote computer in association with identification information to identify the reagent container. Thus, it is possible to automatically identify the reagent, which should not be used, and to manage the reagent not so as to use it for the analysis. In addition, it is possible to use the data for the enhancement of the business efficiency such as the automatic order of the reagent, the stock management in the manufacturer and the like. |
| US08772035B2 |
Process for controlling ionic liquid catalyst activity by titration
A process for determining ionic liquid catalyst deactivation including (a) collecting at least one sample of an ionic liquid catalyst; (b) hydrolyzing the at least one sample to provide at least one hydrolyzed sample; (c) titrating the at least one hydrolyzed sample with a basic reagent to determine a volume of the basic reagent necessary to neutralize a Lewis acid species of the ionic liquid catalyst; and (d) calculating the acid content of the at least one sample from the volume of basic reagent determined in step (c) is described. Processes incorporating such a process for determining ionic liquid catalyst deactivation are also described. These processes are an alkylation process, a process for controlling ionic liquid catalyst activity in a reaction producing by-product conjunct polymers, and a continuous process for maintaining the acid content of an ionic liquid catalyst at a target acid content in a reaction producing by-product conjunct polymers. |
| US08772034B2 |
Control solution packets and methods for calibrating bodily fluid sampling devices
A control solution packet for calibrating a bodily fluid sampling device includes a container, a control solution pressurized within the container, and a membrane for covering and sealing the container. The control solution can be pressurized before or during calibration so as to ensure the appropriate amount of control solution is delivered to the bodily fluid sampling device. The control solution is manufactured to have a viscosity that controls delivery of the control solution to the device. The membrane is permeable by a piercing device of the bodily fluid sampling device and seals around the piercing device during calibration. In another aspect, the container is in the form of a capsule or dosing attachment that contains the control solution along with a sponge-like material. |
| US08772033B2 |
Methods of multiplying plant embryogenic tissue in a bioreactor
The present invention provides methods of multiplying plant embryogenic tissue in a bioreactor. |
| US08772032B2 |
Methods and materials for stimulating proliferation of stem cells
Disclosed herein are methods and materials for influencing proliferation of stem cells. Specifically exemplified herein are compositions comprising cerium oxide nanoparticles which can be used to stimulate proliferation of stem cells under common culture conditions, or which can be utilized to improve therapeutic outcomes. |
| US08772031B2 |
Composition for reprogramming somatic cells to generate induced pluripotent stem cells, comprising Oct4 in combination with Bmi1 or its upstream regulator, and method for generating induced pluripotent stem cells using the same
Disclosed is a composition for reprogramming somatic cells to generate embryonic stem cell-like cells, comprising: a) a Bmi1 (B cell-specific Moloney murine leukemia virus integration site 1) protein or a nucleic acid molecule coding for Bmi1; and b) an Oct4 protein or a nucleic acid molecule coding for Oct4. Also, a method is provided for reprogramming somatic cells to generate embryonic stem cell-like cells using the composition. In addition to reducing the number of the genetic factors conventionally needed, the composition and method allow the generation of pluripotent embryonic stem cell-like cells which have high potential in the cell therapy of various diseases. |
| US08772025B2 |
Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins. |
| US08772022B2 |
Hepatitis C virus expressing reporter tagged NS5A protein
Hepatitis C reporter viruses containing Core through NS2 of prototype isolates of all major HCV genotypes and the remaining genes of isolate JFH1, by insertion of reporter genes in domain III of HCV NS5A were developed. A deletion upstream of the inserted reporter gene sequence conferred favorable growth kinetics in Huh7.5 cells to these viruses. These reporter viruses can be used for high throughput analysis of drug and vaccine candidates as well as patient samples. JFH1-based intergenotypic recombinants with genotype specific homotypic 5′UTR, or heterotypic 5′UTR (either of genotype 1a (strain H77) or of genotype 3a (strain S52)) were also developed. The present inventors additionally developed J6/JFH1 recombinants with the 5′UTR of genotypes 1-6. These recombinants with different 5′UTRs are a useful to study the function of the 5′UTR in a genotype specific manner. |
| US08772018B2 |
Media for affinity chromatography
The invention relates generally to solid supports for chromatography. In specific embodiments the invention provides for solid supports suitable for affinity chromatography along with methods, systems and kits which use the same. |
| US08772016B2 |
Sealed chip package
The invention provides environmental packages, instruments, and methods for sealing, protecting, and providing analysis chips for processing and analysis. The analysis chips are bonded directly or indirectly to chip carriers which are held within the chambers of an environmental packaging strip. The chambers are sealed with a sealing film such that the chip carriers can be extracted using a piercing tool and an extraction tool. |
| US08772002B1 |
Method for treatment of microorganisms during propagation, conditioning and fermentation using hops acid extracts and organic acid
A method of reducing undesirable microorganism concentration, the method comprises (a) introducing a quantity of fermentable carbohydrate, sugar or cellulose to an aqueous system, (b) introducing a quantity of desirable microorganism to the aqueous system, (c) introducing a hops acid extract into the aqueous system and (d) introducing an organic acid solution into said system. |
| US08771999B2 |
Low energy, high substrate efficiency, anaerobic, deep, bubble column fermentation processes
Bioconversion processes are disclosed that enable high conversion efficiencies of gas substrate containing both carbon monoxide and hydrogen to oxygenated organic compounds via the carbon monoxide and hydrogen pathways using anaerobic, deep, bubble column fermentation in a cost effective manner. The high conversion efficiency processes of this invention comprise the combination of using at least two deep, bubble column reactors in flow series and using certain feed gas compositions and microbubbles while avoiding carbon monoxide inhibition. |
| US08771998B2 |
Process for the production of gamma-aminobutyric acid
The present invention relates to a novel method for the fermentative production of gamma-aminobutyric acid (GABA) by cultivating a recombinant microorganism expressing an enzyme having a glutamate decarboxylase activity. The present invention also relates to corresponding recombinant hosts, recombinant vectors, expression cassettes and nucleic acids suitable for preparing such hosts as well as to a method for preparing polyamides making use of GABA as obtained fermentative production. |
| US08771997B2 |
Method for producing monatin using an L-amino acid aminotransferase
The present invention provides a methodology for improving a yield of 2R,4R-Monatin. Specifically, the present invention provides a method for producing 2S,4R-Monatin or a salt thereof, comprising contacting 4R-IHOG with an L-amino acid aminotransferase in the presence of an L-amino acid to form the 2S,4R-Monatin; a method for producing 2R,4R-Monatin or a salt thereof, comprising isomerizing the 2S,4R-Monatin to form the 2R,4R-Monatin; and the like. These production methods may further comprise condensing indole-3-pyruvate and pyruvate to form the 4R-IHOG, and deaminating a tryptophan to form the indole-3-pyruvate. |
| US08771995B2 |
Enzymatic synthesis of sulfated polysaccharides
Heparin is synthesized from a polysaccharide comprised of a 1-4 glycosidically linked alternating polymer of uronic acid and glucosamine residues, wherein the uronic acid is selected from iduronic and glucuronic acid, wherein the glucosamine is partially N-sulfated; by a series of selective reactions catalyzed by recombinant enzymes. |
| US08771993B1 |
Polypeptides having endoglucanse activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having endoglucanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| US08771991B2 |
SOAT polypeptide reaction mixture
The invention relates to sialate-O-acetyltransferase (SOAT) polypeptides, nucleic acids that encode the polypeptides, and methods of using the polypeptides. |
| US08771987B2 |
Mammalian cell lines for increasing longevity and protein yield from a cell culture
Disclosed are compositions and methods for increasing the longevity of a cell culture and permitting the increased production of proteins, preferably recombinant proteins, such as antibodies, peptides, enzymes, growth factors, interleukins, interferons, hormones, and vaccines. Cells transfected with an apoptosis-inhibiting gene or vector, such as a triple mutant Bcl-2 gene, can survive longer in culture, resulting in extension of the state and yield of protein biosynthesis. Such transfected cells exhibit maximal cell densities that equal or exceed the maximal density achieved by the parent cell lines. Transfected cells can also be pre-adapted for growth in serum-free medium, greatly decreasing the time required to obtain protein production in serum-free medium. In certain methods, the pre-adapted cells can be used for protein production following transformation under serum-free conditions. The method preferably involves eukaryotic cells, more preferably mammalian cells. |
| US08771986B2 |
Engineered cleavage half-domains
Disclosed herein are engineered cleavage half-domains; fusion polypeptides comprising these engineered cleavage half-domains; polynucleotides encoding the engineered cleavage half-domains and fusion proteins; and cells comprising said polynucleotides and/or fusion proteins. Also described are methods of using these polypeptides and polynucleotides, for example for targeted cleavage of a genomic sequence. |
| US08771985B2 |
Genome editing of a Rosa locus using zinc-finger nucleases
Disclosed herein are methods and compositions for genome editing of a Rosa locus, using fusion proteins comprising a zinc-finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins. |
| US08771982B2 |
Chimeric molecule and nucleic acid encoding same
The present invention relates, in general, to telomeres, and, in particular, to a method or effecting telomere elongation in mammalian cells. The invention further relates to a protein suitable for use in such a method and to nucleic acid sequences encoding same. |
| US08771980B2 |
Combined liquid to solid-phase anaerobic digestion for biogas production from municipal and agricultural wastes
Biogas is obtained in a solid-state anaerobic digester from a solid organic biomass and a digestion effluent produced in an associated liquid anaerobic digester. The solid organic biomass and digestion effluent are mixed to produce an effluent-biomass mixture. The effluent-biomass mixture is then incubated in the solid state anaerobic digester, producing a biogas and a digestate. The incubation is controlled by adjusting the composition and properties of the effluent-biomass mixture. The solid organic biomass may comprise lignocellulosic biomass, food waste, agricultural waste and the like. |
| US08771979B2 |
Process for production of biomass from a carbon source
The present invention relates to microorganisms genetically engineered to increase yield and/or efficiency of biomass production from a carbon source, such as e.g. glucose. Also included are processes of using the polynucleotides and modified polynucleotide sequences to transform host microorganisms leading to a microorganism with reduced carbon source diversion, i.e. higher yield and/or efficiency of biomass production from a carbon source such as e.g. glucose. |
| US08771975B2 |
Quantitation of GCP activity in biological samples
Provided herein are methods for quantitating glutamate carboxypeptidase II activity in a biological sample, such as a skin biopsy sample, and for determining whether an agent is inhibiting GCP in a subject. |
| US08771972B2 |
Clozapine immunoassay
Novel conjugates and immunogens derived from clozapine and antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of clozapine in biological fluids. |
| US08771971B2 |
Methods and kits for measurement of lymphocyte function
The present invention provides simple and rapid methods for measuring the function of a desired subset of lymphocytes, for example, T cells, B cells or NK cells. In addition, the present invention provides an all-in-one kit that contains reagents which permit a rapid and reliable analysis of the functions of T cells, B cells and NK cells obtained directly from whole blood or cord blood. |
| US08771969B2 |
Peptide antibody depletion and its application to mass spectrometry sample preparation
The present invention relates, e.g., to a method for pre-processing a sample for mass spectral analysis, comprising cleaving proteins in the sample to peptides and immunodepleting highly abundant and/or well-ionizing and/or proteotypic peptides from the sample. Also described are methods for identifying well-ionizing peptides for use in this and other methods; analytic (diagnostic) methods using antibodies against highly ionizable peptides from a protein target of interest; and compositions, kits and devices comprising antibodies of the invention. |
| US08771967B2 |
Immunomodulation of functional T cell assays for diagnosis of infectious or autoimmune disorders
Improved assays for detecting the presence of a specific cell-mediated immune response in an individual are provided, where a sample comprising T cells and other cells of the immune system, usually a blood sample or derivative thereof, is contacted with test antigen(s) of interest in the presence of a pattern recognition receptor (PRR) agonist. The sample is incubated for a period of time sufficient to activate effector T cells; and release of immune effector molecule(s) is then detected. In some embodiments, the PRR is an agonist of a toll-like receptor (TLR) expressed by mature antigen presenting cells, including without limitation agonists TLR3 and TLR7, such as LPS, poly I:C, imiquimod, etc. |
| US08771966B2 |
Immuno-PET imaging of antibodies and immunoconjugates and uses therefor
Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of detecting or determining the presence of STEAP-1 proteins are provided. |
| US08771965B2 |
Methods and compositions involving nucleotide repeat disorders
The present invention concerns the methods and compositions involving nucleic acids with long repeat sequences. In some embodiments of the invention, there are methods for generating such a nucleic acid, and in other methods, there are methods for using such a nucleic acid to screen for candidate therapeutic compounds. Furthermore the present invention relates to methods of screening for Notch inhibitors and other substances that may be used to treat muscle loss and wasting. |
| US08771963B2 |
Method of diagnosing esophageal cancer
In order to identify the molecules involved in esophageal carcinogenesis and those to be useful for diagnostic markers as well as targets for new drugs and immunotherapy, a cDNA microarray representing 32,256 genes was constructed to analyze the expression profiles of 19 esophageal squamous-cell carcinomas (ESCCS) purified by laser-capture microdissection. A detailed genome-wide database for sets of genes that are significantly up- or down-regulated in esophageal cancer is disclosed herein. These genes find use in the development of therapeutic drugs or immunotherapy as well as tumor markers. Additionally, genes associated with lymph-node metastasis and post-surgery recurrence are disclosed herein. Among the candidate molecular target genes, ECT2, CDC45L and DKK1 are further characterized. Treatment of ESCC cells with small interfering RNAs (siRNAs) of ECT2 or CDC45L suppressed growth of the cancer cells. Thus, the data herein provide valuable information for identifying diagnostic systems and therapeutic target molecules for esophageal cancer. |
| US08771961B2 |
Monitoring myocardial infarction and its treatment
Disclosed is a method of determining which medication is to be applied in a remodeling process of a subject after a myocardial infarction, the method comprising determining an amount of a natriuretic peptide, a cardiac troponin, and an inflammatory marker in a sample from the subject and initiating a remodeling in the subject, wherein the medication to be applied in the remodeling is selected according to the level of the peptides determined. Also disclosed is a method of monitoring the remodeling, wherein further steps include again determining an amount of the natriuretic peptide, the cardiac troponin, and the inflammatory marker in a sample from the subject, calculating the difference between the values from the first and second measurements, and assessing remodeling success from the data obtained. |
| US08771956B2 |
Modulation of human mouse double minute 2 homolog activity
The invention is directed to isolated genomic polynucleotide fragments that encode human carboxypeptidase M and human mouse double minute 2 homolog, vectors and hosts containing these fragments and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain human carboxypeptidase M and human mouse double minute 2 homolog and to diagnose, treat, prevent and/or ameliorate a pathological disorder. |
| US08771955B2 |
Device and method for extraction and analysis of nucleic acids from biological samples
Device and methods for extracting and analyzing nucleic acids from biological samples. |
| US08771952B2 |
Substances and methods for a DNA based profiling assay
The present invention relates to a DNA profiling assay comprising the following steps, providing a sample to be analyzed, providing reagents, enzyme and primeroligonucleotides which are necessary for simultaneous polymerase chain reaction amplification of at least 20 loci, amplifying the loci, detecting the amplification products, wherein the amplification products and the loci to be amplified are characterized by the following features, each locus to be amplified is characterized by at least one deletion-insertion polymorphism known to be present in the population, wherein the two alleles from each locus differ in size by more than 2 nucleotides and less than 100 nucleotides, a first set of at least two amplification products ranging in size from about 20 nucleotides to about 300 nucleotides stemming from at least two different loci carries a first label, a second set of at least two amplification products ranging in size from about 20 nucleotides to about 300 nucleotides stemming from at least two different loci carries a second label, a third set of at least two amplification products ranging in size from about 20 nucleotides to about 300 nucleotides stemming from at least two different loci carries a third label, label one, label two and label three are each different fluorescent labels which can he differentiated and simultaneously detected by a multi-color detector in combination with, e.g. a DNA sequencing device. |
| US08771948B2 |
Nucleic acid preparation compositions and methods
Provided herein are methods and compositions to extract and enrich by, physical separation or amplification, relatively short nucleic acids from a nucleic acid composition containing a high background of longer nucleic acids (e.g., host or maternal nucleic acids; genomic nucleic acid and the like). |
| US08771946B2 |
PKD mutations and evaluation of same
The present invention relates to methods of detecting novel mutations in a PKD1 and/or PKD2 gene that have been determined to be associated with autosomal dominant polycystic kidney disease (ADPKD) in order to detect or predict the occurrence of ADPKD in an individual. |
| US08771944B2 |
Use of micro-RNA as a biomarker of immunomodulatory drug activity
Methods of determining the activity of an immunomodulatory compound by measuring the presence of an miRNA in a sample are disclosed. Additionally disclosed are methods of assessing the patient compliance in patients treated with an immunomodulatory compound. |
| US08771941B2 |
Methods of assessing the risk of reproductive failure by measuring telomere length
The invention features a method of identifying oocytes with a risk of reproductive failure and/or aneuploidy based on a telomere length assay. |
| US08771938B2 |
Microfluidic platforms for multi-target detection
Disclosed are example methods and devices for detecting one or more targets. An example method includes placing a sample including a first target with in a microfluidic device and hybridizing a plurality of copies of the first target with a plurality of nanostructures. The example method includes applying an electric current to the plurality of nanostructures and using an electric field created by the electric current to move the plurality of nanostructures. In addition, the plurality of nanostructures are sorted and evaluated to determine at least one of a presence, an absence, or a quantity of the first target. |
| US08771937B2 |
Methods for diagnosing and treating a pathology associated with a synonymous mutation occuring within a gene of interest
The present invention relates to a method for diagnosing and/or prognosing a pathology (such as inflammatory disease, especially Crohn disease) associated with a synonymous mutation occurring within a gene of interest (such as IRGM, NOD2 or BSN) in a subject and to a method for treating such pathology in a subject. |
| US08771936B2 |
Bacteriophage and antibacterial composition comprising the same
The present invention relates to a novel bacteriophage, more particularly, a bacteriophage that has a specific bactericidal activity against Salmonella typhimurium, Salmonella gallinarum, or Salmonella pullorum, a composition for the prevention or treatment of infectious diseases including salmonellosis and Salmonella food poisoning caused by Salmonella typhimurium, Fowl typhoid caused by Salmonella gallinarum, and Pullorum disease caused by Salmonella pullorum, which comprises the bacteriophage as an active ingredient, and an animal feed, drinking water, cleaner, and sanitizer which comprise the bacteriophage as an active ingredient. The present invention also provides important insights into prevention and control strategies against Salmonella infection and suggests that the use of bacteriophage can be a novel, safe, and effectively plausible alternative to antibiotics for the prevention of Salmonella infection in poultry. |
| US08771934B2 |
Inorganic pyrophosphate and uses thereof
The present invention provides a new and improved sperm stimulating additive comprising a certain amount of inorganic pyrophosphate (PPi). Addition of PPi in the media for human/animal in vitro fertilization (IVF) improves fertilization rate; addition of PPi in the semen extender for farm animal artificial insemination (AI) may improve pregnancy rates; furthermore, mammalian oocytes matured in vitro in a medium including PPi attain improved fertilization and developmental potential, while embryos cultured in medium supplemented with PPi have improved development to blastocyst. |
| US08771933B2 |
Continuous-flow deformability-based cell separation
This invention provides methods utilizing a microfluidic device that can quickly and accurately discern differences in deformability between individual cells and sets of cells and continuously fractionate populations of cells based on their deformability. This information may be important in disease diagnosis and treatment efficacy monitoring. For example such a device may be able to determine the stage of malarial infection by using red blood cell deformability. Additionally, methods of the invention may be used as a tool to screen drugs that can make cells more flexible in diseases such as sickle cell anemia that causes sickle cell crises. The relatively low manufacturing and operation costs of methods of the invention enable this device to be used in resource-limited settings to diagnose and monitor disease. |
| US08771932B2 |
Rationally designed antibodies
Antibodies or fragments thereof having CDR regions replaced or fused with biologically active peptides are described. Flanking sequences may optionally be attached at one or both the carboxy-terminal and amino-terminal ends of the peptide in covalent association with adjacent framework regions. Compositions containing such antibodies or fragments thereof are useful in therapeutic and diagnostic modalities. |
| US08771931B2 |
Perfusion culture method and perfusion culture device for organ or tissue
Disclosed are a perfusion culture method and a perfusion culture device whereby a perfusate can be delivered to all parts of an organ or tissue so that the organ or tissue can be preserved while sufficiently maintaining the function thereof. Specifically disclosed is a method for perfusion culture of an organ or tissue removed from a mammal, said organ or tissue having been removed together with a second organ or tissue connected to the aforesaid organ or tissue in vivo, which comprises a step for fixing said second organ or tissue so as to hang the aforesaid organ or tissue and a step for perfusing blood vessels in the aforesaid organ or tissue with a perfusate. |
| US08771927B2 |
Acid-etch resistant, protective coatings
New compositions and methods of using those compositions as protective layers during the production of semiconductor and MEMS devices are provided. The compositions comprise a cycloolefin copolymer dispersed or dissolved in a solvent system, and can be used to form layers that protect a substrate during acid etching and other processing and handling. The protective layer can be photosensitive or non-photosensitive, and can be used with or without a primer layer beneath the protective layer. Preferred primer layers comprise a basic polymer in a solvent system. |
| US08771925B2 |
Flexographic processing solution and method of use
A processing solution is used to provide flexographic relief printing plates. This solution includes diisopropylbenzene, and one or more organic co-solvents, at least one of which is an aliphatic dibasic acid ester. The processing solution may also include one or more alcohols as co-solvents. |
| US08771924B2 |
Polymerizable composition, lithographic printing plate precursor and lithographic printing method
A polymerizable composition contains a binder polymer containing a functional group having a dipole moment of 3.8 debye or more and being represented by the formula (1), (2), (3), (4) or (5) as defined herein, a radical polymerizable compound and a radical polymerization initiator. |
| US08771922B2 |
Copolymer for resist comprising novel acryl based monomer and resin composition for resist comprising the same
A resist resin composition includes 100 parts by weight of a copolymer represented by Formula 3 below; 0.5 to 1.5 parts by weight of a photoacid generator and 700 to 1,500 parts by weight of a solvent: wherein R1, R2, and R3 are each independently a C1-30 alkyl group, a C3-30 cycloalkyl group, an ether group, an ester group, a carbonyl group, an acetal group, an epoxy group, a nitrile group, or an aldehyde group, R4, R5, and R6 are each independently hydrogen or a methyl group, and l, m, n, and o each independently refer to the number of repeating units in a main backbone and satisfy the conditions: l+m+n+o=1, 0≦l/(l+m+n+o)<0.4, 0 |
| US08771919B2 |
Laser marking process and articles
A process to mark a multilayered article with a laser (20). The multilayered article (10) includes a laser-markable layer (14) having at least one organic polymer and at least one light-sensitive pigment therein, and including at least one release agent associated with the laser-markable layer. Laser-marking of the laser-markable layer is accomplished by directing laser radiation (22) into the multilayered article through the release agent (12) to induce an interaction between the light-sensitive pigment and the organic polymer. As a result of the interaction, a visually perceptible marking (16) is formed in the article. The laser-marked article includes a laser-markable layer and a first release agent associated with a surface of the laser-markable layer. The marking(s) in the laser-markable layer is visible through the layer of release agent, and the marking is a result of the laser-induced interaction between the light-sensitive pigment and the organic polymer. |
| US08771917B2 |
Monomers, polymers, photoresist compositions and methods of forming photolithographic patterns
Provided are (meth)acrylate monomers containing acetal moieties, polymers containing a unit formed from such a monomer and photoresist compositions containing such a polymer. The monomers, polymers and photoresist compositions are useful in forming photolithographic patterns. Also provided are substrates coated with the photoresist compositions, methods of forming photolithographic patterns and electronic devices. The compositions, methods and coated substrates find particular applicability in the manufacture of semiconductor devices. |
| US08771916B2 |
Actinic ray-sensitive or radiation-sensitive resin composition and pattern forming method using the same
An actinic ray-sensitive or radiation-sensitive resin composition, includes: (A) a resin capable of increasing the solubility of the resin (A) in an alkali developer by the action of an acid; and (C) a resin having at least either a fluorine atom or a silicon atom and containing (c) a repeating unit having at least two or more polarity conversion groups. |
| US08771914B2 |
Toner for developing latent electrostatic image, two-component developer, image forming method and image forming apparatus
The present invention provides a toner which, despite its spherical shape, makes it possible to prevent an external additive from being embedded in the toner easily or by a load generating low stress, reduce variation in image density, maintain cleaning ability and transfer ability throughout its long-term use and obtain excellent image quality, and further, provides a two-component developer, an image forming method and an image forming apparatus with the use of the toner. There is a toner including: base particles including a colorant and a resin, and hard fine particles, wherein the base particles and the hard fine particles are mixed together, and protruding portions formed of fine organic resin particles which are different in composition from a resin contained as a main component in the base particles are provided on surfaces of the base particles. |
| US08771913B1 |
Cardanol derivatives in polyester toner resins
The present disclosure provides a polyester toner resin comprising a polyhydroxylated cardanol derivative, that may be used in manufacturing an emulsion aggregation (EA) toner for imaging devices. |
| US08771907B2 |
Positive photosensitive resin composition and method of forming cured film from the same
According to one embodiment, a positive photosensitive resin composition includes a resin containing a specified acrylic acid besed-structural unit which generates a carboxyl group when its dissociative group is dissociated, which resin is insoluble in alkali or sparingly soluble in alkali but when its acid-dissociative group is dissociated, becomes soluble in alkali, a resin containing a structural unit derived from a radical-polymerizable monomer containing an epoxy group, a compound containing two or more epoxy groups in its molecule, provided that the resin containing the structural unit derived from a radical-polymerizable monomer containing an epoxy group is not included in this compound, and a compound that when exposed to actinic rays of 300 nm or longer wavelength, generates an acid. |
| US08771904B2 |
Method for producing holographic media
The invention relates to a method for producing holographic media, wherein a photopolymer formulation comprising matrix polymers, writing monomers, a photoinitiator system, and optionally auxiliary materials and additives as components is provided, the photopolymer formulation is applied as a coating on the surface of a carrier film and the photopolymer formulation is dried on the carrier film at a temperature XX |
| US08771903B2 |
Method for producing a holographic film
The invention relates to a method for producing holographic films, in which a photopolymer formulation is provided which comprises as constituents matrix polymers, writing monomers, a photoinitiatior system, optionally a non-photopolymerizable component and optionally catalysts, radical stabilizers, solvents, additives and other auxiliaries and/or additives. The photopolymer formulation is applied in a planar manner and in the form of a film on a support film and the photopolymer formulation is dried on the support film at a temperature 60 |
| US08771902B2 |
Manufacture of fuel cell
A fuel cell is manufactured using a polymer electrolyte membrane (1). A catalyst layer (12) is formed at fixed intervals on the surface of the strip-form polymer electrolyte membrane (1) in the lengthwise direction thereof, and conveyance holes (10) are formed in series at fixed intervals on the two side portions thereof. By rotating a conveyance roller (32) comprising on its outer periphery projections which engage with the holes (10), the polymer electrolyte membrane (1) is fed from a reel (9). A GDL (6) and a separator (7) are adhered to the fed polymer electrolyte membrane (1) at a predetermined processing timing based on the rotation speed of the conveyance roller (32), and thus the fuel cell is manufactured efficiently while the GDL (6) and separator (7) are laminated onto the catalyst layer (12) accurately. |
| US08771901B2 |
SOFC stack having a high temperature bonded ceramic interconnect and method for making same
The present disclosure is directed to an integrated SOFC stack including, a first cell having a cathode layer, an electrolyte layer overlying the cathode layer, and an anode layer overlying the electrolyte layer. The SOFC stack also includes a second cell having a cathode layer, an electrolyte layer overlying the cathode layer, and an anode overlying the electrolyte layer. The SOFC stack further includes a ceramic interconnect layer between the first cell and the second cell, the ceramic interconnect layer having a first high temperature bonding region along the interfacial region between the first cell and the ceramic interconnect layer. The ceramic interconnect layer also includes a second high temperature bonding region along the interfacial region between the second cell and the ceramic interconnect layer. |
| US08771898B2 |
Arrangement of components in a solid oxide fuel cell and manufacturing method thereof
Described herein are solid oxide fuel cells and manufacturing methods thereof. In certain aspects, the solid oxide fuel cells described herein include a plurality of anodes and a plurality of cathodes in which the anodes and cathodes are alternately stacked on each other and have non-overlapping sections in which the anodes and cathodes do not overlap partially. In certain aspects, the plurality of anodes are electrically connected to a first electrode, and the plurality of cathodes are electrically connected to a second electrode. In certain aspects, a solid electrolyte can be included, for example, between the anode and the cathode. In certain aspects, partitioning sections are disposed between each of the cathodes and the first electrode and between each of the anodes and the second electrode. |
| US08771894B2 |
Cooling plate having improved flow channels
A cooling plate in which flow channels are modified to reduce temperature differences between portions of the cooling plate and provide for more uniform heat distribution within a heat generator. The flow channels of the cooling plate are formed such that a central portion of the flow channels has a greater volume than the end portions near an inlet and an outlet so that the amount of cooling water that is contained in the central portion at any one time is larger than either of the end portions near the inlet and the outlet. Likelihood of thermal deformation of the cooling plate due to thermal stress is decreased, and stability of performance of the fuel cell is increased. |
| US08771888B2 |
Fuel cell system and method of load following operation of the same
Provided is a fuel-cell system and a method of operating the fuel-cell system, wherein functions F=f(P) and P=f−1(F) of electrical output P and fuel flow-rate F required to output P are beforehand obtained, and a reformable fuel flow-rate FR is calculated from the temperature of reforming catalyst layer. When FR≧Fmin, if the output demand PD≦maximum output PM, and when f(PD)≦FR, F is set to f(PD); and when f(PD)>FR, the P is set to the maximum value within a range of less than PD amongst P calculated from P=f1(FR), and F is set to FR. When PD>PM, and when f(PM)≦FR, the cell output is set to PM, and F is set to f(PM). When f(PM)>FR, the cell output is set to the maximum value amongst P calculated from P=f1(FR), and F is set to FR. |
| US08771887B2 |
Method of operating a fuel cell apparatus
Method of operating a fuel cell apparatus in which a reforming reaction in the reforming portion is selected by a controller at the starting time of the apparatus by comparing a first starting temperature of a reforming portion to a temperature T1 at which steam reforming can be performed and comparing a second starting temperature of a vaporizing portion to a temperature T2 at which a predetermined amount of steam can be generated by steam reforming. A reforming reaction starting with an autothermal reforming reaction is performed when the first starting temperature is not lower than T1 and the second starting temperature is lower than T2. |
| US08771881B2 |
Electrolyte for lithium ion secondary battery and lithium ion secondary battery comprising the same
An electrolyte for a lithium ion secondary battery includes a non-aqueous organic solvent; a lithium salt; and a phosphonitrile fluoride trimer as an additive, and a lithium ion secondary battery comprising the same. The thickness increase rate of a lithium ion secondary battery including the electrolyte is reduced even when the battery is kept at a high temperature. Thus, the thermal stability and durability of the battery are prominently improved. The durability of the battery can be further improved by including a vinylene carbonate or ethylene carbonate group compound in the electrolyte. |
| US08771880B2 |
Binder for separator of non-aqueous electrolyte battery comprising 2-cyanoethyl group-containing polymer and separator and battery using the same
Object of the invention is to provide a binder for a separator which can be comprised by a non-aqueous electrolyte battery with improved battery properties and heat resistance; the separator comprising the binder; and the non-aqueous electrolyte battery comprising the separator. More specifically, provided is a binder for a separator of a non-aqueous electrolyte battery, the separator comprising a 2-cyanoethyl group-containing polymer having bis-cyanoethyl ether content of 0.5% by weight or less as an impurity. |
| US08771879B2 |
Lithium—sulfur battery with a substantially non-porous lisicon membrane and porous lisicon layer
A lithium-sulfur battery is disclosed in one embodiment of the invention as including an anode containing lithium and a cathode comprising elemental sulfur. The cathode may include at least one solvent selected to at least partially dissolve the elemental sulfur and Li2Sx. A substantially non-porous lithium-ion-conductive membrane is provided between the anode and the cathode to keep sulfur or other reactive species from migrating therebetween. In certain embodiments, the lithium-sulfur battery may include a separator between the anode and the non-porous lithium-ion-conductive membrane. This separator may prevent the lithium in the anode from reacting with the non-porous lithium-ion-conductive membrane. In certain embodiments, the separator is a porous separator infiltrated with a lithium-ion-conductive electrolyte. |
| US08771877B2 |
Positive electrode material for nonaqueous electrolyte secondary battery, nonaqueous electrolyte secondary battery including the same, and method for producing the same
Disclosed is a positive electrode material for nonaqueous electrolyte secondary batteries, which comprises a porous body composed of a material containing a polyanion. Also disclosed is a method for producing such a positive electrode material for nonaqueous electrolyte secondary batteries. When a carbon coating is formed on the surface of a material containing a polyanion of lithium iron phosphate or the like by a conventional method, the capacity during low rate discharge is improved but the capacity is not sufficient. In the present invention, the positive electrode material for nonaqueous electrolyte secondary batteries, which comprises a porous body composed of a material containing a polyanion, has a structure wherein the inner walls of the pores of the porous body are provided with a layered carbon, for improving the discharge capacity. |
| US08771873B2 |
Lithium secondary battery and method of manufacturing the same
A lithium secondary battery includes an electrode assembly having a positive electrode (1), a negative electrode (2) having a negative electrode current collector and a negative electrode active material layer formed on a surface of the negative electrode current collector and composed of a binder and negative electrode active material particles containing silicon and/or a silicon alloy, and a separator (3) interposed between the electrodes. The electrode assembly is impregnated with a non-aqueous electrolyte. The binder contains a polyimide resin represented by the following chemical formula (1): where R contains at least a benzene ring, and n is within the range of from 10 to 100,000, and the negative electrode active material particles have an average particle size of 5 μm or greater. |
| US08771871B2 |
Lead storage battery and manufacturing method of the same
There is disclosed a lead storage battery comprising a group of plates housed in a battery jar, and an electrolyte injected therein to impregnate the group of plates with the electrolyte, thus performing formation treatment, the lead storage battery being adapted to be used in a partial state of charge where the state of charge is confined within the range of more than 70% to less than 100%, wherein the group of plates are formed of a stack constituted by a large number of negative substrates comprising grid substrates filled with a negative active material, by a large number of positive substrates comprising grid substrates filled with a positive active material, and by a porous separator interposed between the negative electrodes and positive electrodes, and the electrolyte contains at least one kind of ion selected from the group consisting of aluminum ions, selenium ions and titanium ions. |
| US08771868B2 |
Electrode structure and battery device manufacturing method
An electrode is provided with a metal terminal extending from a battery module main body, a bolt which has an expanded section configuring a retaining section at a rear end portion and penetrates the metal terminal upward, and an insulating body which insulates the metal terminal and the battery module case one from the other. The insulating body is provided with a drop preventing section which abuts at least a lower surface of the expanded section of the bolt and prevents the bolt from dropping from the metal terminal. |
| US08771866B2 |
Pouch type secondary battery and the fabrication method thereof
A method of forming a secondary battery comprises: positioning an electrode assembly between a first pouch sheet and a second pouch sheet; initially sealing outer portions of the first pouch sheet and of the second pouch sheet on at least one side of the first and second pouch sheets; and additionally sealing outer portions of the first pouch sheet and of the second pouch sheet on the at least one side of the first and second pouch sheets. |
| US08771865B2 |
Secondary battery
A secondary battery including an electrode assembly, and a case, the case including a pair of long side walls facing each other, and a pair of short side walls at ends of the long side walls, and accommodating the electrode assembly in a space defined by the long side walls and the short side walls, each short side wall including a bottom region and a top region, the bottom region and top region each having a thickness, and the thickness of the bottom region being greater than the thickness of the top region. |
| US08771860B2 |
Lithium secondary battery and method for manufacturing same
A lithium secondary battery provided by the present invention includes a spirally wound electrode body in which a positive electrode sheet and a negative electrode sheet are spirally wound with a separator sheet 40 interposed therebetween, wherein on a sheet surface of at least any one from among the positive electrode sheet, negative electrode sheet, and separator sheet 40 constituting the spirally wound electrode body, a porous layer 60 is formed along a longitudinal direction of the sheet 40, and the porous layer 60 is thicker in a spiral winding direction of the spirally wound electrode body in a winding center portion 62 than in a winding outer portion 64. |
| US08771857B2 |
Redox flow battery
A redox flow (RF) battery performs charge and discharge by supplying a positive electrode electrolyte and a negative electrode electrolyte to a battery cell. Each of the positive electrode electrolyte and the negative electrode electrolyte contains a vanadium (V) ion as active material. At least one of the positive electrode electrolyte and the negative electrode electrolyte further contains another metal ion, for example, a metal ion such as a manganese ion that exhibits a higher redox potential than a V ion or a metal ion such as a chromium ion that exhibits a lower redox potential than a V ion. |
| US08771855B2 |
Alkali metal aqueous battery
A battery cell is described that has an anode made of an alkali metal or alkali metal alloy, an alkali metal conductive membrane, and a cathode compartment that houses a hydrogen evolving cathode and a catholyte. The catholyte has dissolved salt comprising cations of the alkali metal. The battery also includes a zone where hydrogen may vent from the catholyte and a zone where water may transport into the catholyte. The zone where water may transport into the catholyte restricts the transport of ions. The battery may be operated (1) in freshwater where there is low ion-conductivity and (2) in seawater where there is a quantity of cations (such as sodium ions) that are incompatible with the alkali metal conductive membrane. The battery is designed such that the alkali metal conductive membrane is protected from cations that operate to foul the alkali metal conductive membrane. |
| US08771852B2 |
Battery pack with contactless power transfer
A battery pack that includes a secondary battery, a resin structure including the secondary battery, and a flat-shaped, contactless power transfer coil embedded at a first face side of the resin structure. The resin structure contains a magnetic material at least at the first face side thereof. |
| US08771850B2 |
Carbon-deuterium protective overcoat layer
A substrate having a carbon-deuterium protective overcoat layer, and method for making the same. In some embodiments, the substrate includes a recording structure having a magnetic recording layer. A protective overcoat layer is Formed on the recording structure, the protective overcoat layer composed of carbon-carbon (C—C) and carbon-deuterium (C-D) bonds and having no carbon-hydrogen (C—H) bonds. |
| US08771847B2 |
Reader stop-layers
Tolerances for manufacturing reader structures for transducer heads continue to grow smaller and storage density in corresponding storage media increases. Reader stop layers may be utilized during manufacturing of reader structures to protect various layers of the reader structure from recession and/or scratches while processing other non-protected layers of the reader structure. For example, the stop layer may have a very low polish rate during mechanical or chemical-mechanical polishing. Surrounding areas may be significantly polished while a structure protected by a stop layer with a very low polish rate is substantially unaffected. The stop layer may then be removed via etching, for example, after the mechanical or chemical-mechanical polishing is completed. |
| US08771842B2 |
Benzo[b]chrysene compound and organic light-emitting element including the same
The present invention provides a benzo[b]chrysene compound represented by general formula [1] below and an organic light-emitting element including the compound. In the general formula [1], Ar represents a substituted or unsubstituted aromatic hydrocarbon group, and R1 to R4 are each independently selected from the group consisting of a hydrogen atom, substituted or unsubstituted alkyl groups, and substituted or unsubstituted aromatic hydrocarbon groups. |
| US08771836B2 |
Resin composition and method for production thereof, and rolling bearing and sliding bearing
It is an object of the present invention to provide a resin composition whose flowability is secured when the resin composition is injection-molded into injection-molded articles such as a resin-made crown-shaped cage and a resin-made seal both for a rolling bearing and a resin-made sliding bearing and which is capable of enhancing the mechanical strengths and toughnesses of these injection-molded articles to such an extent that these injection-molded articles can be used as bearing members. The resin composition is formed into a molded article and used as a bearing member. The resin composition is composed of polyamide resin or polyester resin to which polycarbodiimide is added. The polyamide resin is at least one resin selected from among polyamide 66 resin and polyamide 11 resin. The polyester resin is polytrimethylene terephthalate resin. 0.5 to 6 wt % of the polycarbodiimide is contained in an entirety of the resin composition. A resin-made crown-shaped cage (1) is obtained by injection-molding the resin composition. |
| US08771834B2 |
Formed body, production method thereof, electronic device member and electronic device
The present invention is a formed article sequentially comprising a base layer, a primer layer that includes a hydroxyl group-containing polymer, and a gas barrier layer, the gas barrier layer being formed of a material that includes at least an oxygen atom and a silicon atom, a surface layer part of the gas barrier layer having an oxygen atom content rate of 60 to 75%, a nitrogen atom content rate of 0 to 10%, and a silicon atom content rate of 25 to 35%, based on a total content rate of oxygen atoms, nitrogen atoms, and silicon atoms, and the surface layer part of the gas barrier layer having a film density of 2.4 to 4.0 g/cm3. According to the present invention, provided is a formed article, a method for producing the same, an electronic device member including the formed article, and an electronic device including the electronic device member, with an excellent gas barrier capability and excellent transparency. |
| US08771832B2 |
Lignin/polyacrylonitrile-containing dopes, fibers, and methods of making same
The invention relates to a process for preparing a composition comprising 10 to 45% of the total solids weight lignin, polyacrylonitrile or a polyacrylonitrile copolymer, and a solvent to form a lignin-based polyacrylonitrile-containing dope and the resulting products. The dope can be processed to produce fibers, including precursor, oxidized and carbonized fibers. The oxidized fibers are of value for their flame resistant properties and carbonized fibers are suitable for use in applications requiring high strength fibers, or to be used to form composite materials. |
| US08771829B2 |
Flame retardant thermoplastic polymer composition, method of manufacture, and articles formed therefrom
A thermoplastic polymer composition comprises a cyanophenyl endcapped polycarbonate, a potassium diphenyl sulphon-3-sulphonate; and brominated polycarbonate. In some embodiments, when the thermoplastic polymer composition is in the form of a 3 mm thick extruded sheet, the sheet has a smoke density of less than 200 at an exposure period of 240 seconds in accordance with the smoke density test as set forth in ASTM E662-06, and has no burning drips on the sheet for a duration of 10 minutes in accordance with the flammability test as set forth in NF-P-92-505. |
| US08771828B2 |
Sealing film and a semiconductor device using the same
A sealing film which includes a resin layer having a flow within the range of 150 to 1800 μm at 80° C., or having a resin layer with a viscosity within the range of 10000 to 100000 Pa·s in a B-stage state at 50 to 100° C. in thermosetting viscoelasticity measurement, and containing: (A) both (a1) a high-molecular-weight component including crosslinking functional groups and having a weight-average molecular weight of 100,000 or more and a Tg within the range of −50 to 50° C., and (a2) a thermosetting component including an epoxy resin as a main component, (B) a filler having an average particle size within the range of 1 to 30 μm, and (C) a colorant, as well as a manufacturing method thereof and a semiconductor device using the same. |
| US08771827B2 |
Film for construction and film combination
A film (1) for construction with at least one functional layer (2) and optionally at least one other layer, especially a carrier layer and/or reinforcing layer (3), the functional layer (2) having a water vapor diffusion resistance (sd value) that is dependent on the ambient humidity. The functional layer (2) has at least one material (4) that can be obtained from a renewable raw material, especially at least one polymer based on a renewable raw material. |
| US08771826B2 |
Mineral composition
A roofing shingle that contains a roofing granules. The roofing granules contain at least about 95 weight percent of calcium carbonate with a hardgrove grindability index of less than about 70, and from about 0.1 to about 1.0 weight percent of a pigmented material; the pigmented material contains from about 10 to about 35 weight percent of pigment and from about 90 to about 65 weight percent of a resin; and the roofing granules are coated with an amine antistrip agent. |
| US08771819B2 |
Universal tank overlay
A universal tank overlay is described that can be attached to different sizes and configurations of storage tanks. The overlay comprises a flexible layer of material that includes at least one section. The layer is adapted to connect to a storage tank that includes two opposing end walls that are connected by an at least partially arcuate elongate tubular sidewall. The tank also includes a plurality of pipes that provide for flow into, from and vent the tank. The layer includes at least one aperture that adjusts to receive the plurality of pipes on the tank. The layer has a first position that is separate from the tank and a second position that includes the layer attached to the tank. In the second position the storage tank at least partially covers the tank. The layer is adapted for positioning on the sidewall of the tank. The layer is attached to the tank using fasteners. |
| US08771818B2 |
Electrically conducting member for electrophotography, process cartridge and electrophotographic image forming apparatus
To provide an electrically conducting member for electrophotography that has made itself kept from increasing in electrical resistance with time even in a low temperature and low humidity environment and also has made any ion conducting agent kept from bleeding to its surface. To also provide a process cartridge, and an electrophotographic image forming apparatus, that can stably form high-grade electrophotographic images over a long period of time in a variety of environments. The conductive member for electrophotography has an electrically conducting substrate and an electrically conducting layer, and the electrically conducting layer contains a resin having in the molecule at least one structure selected from structures represented by the formula (1), formula (2) and formula (3) each defined in the specification. The process cartridge and the electrophotographic image forming apparatus each make use of the same. |
| US08771815B2 |
Process for making triglyceride plasticizer
Provided are processes for making, and processes for using triglycerides as plasticizers. The process for making the triglyceride plasticizer includes: (i) recovering at least one linear C4 to C10 aldehyde, one branched C4 to C10 aldehyde, or a combination thereof from a hydroformylation product; (ii) oxidizing the linear, branched or combination thereof C4 to C10 aldehyde to form a linear, branched or combination thereof C4 to C10 acid; (iii) esterifying the linear, branched or combination thereof C4 to C10 acid with a polyol to yield a linear alkyl triglyceride, a branched alkyl triglyceride, or a combination thereof, and reaction byproducts; (iv) purifying the linear, branched or combination thereof alkyl triglyceride to form a plasticizer stream, a reaction byproduct stream, and an unreacted input stream, wherein the total carbon number of the triester groups ranges from 20 to 25 for greater than or equal to 45 wt % of the plasticizer; and (v) recycling from the purifying step back to the esterifying step the unreacted input stream and the reaction byproduct stream. |
| US08771814B2 |
Reusable placemat with strap
A placemat that is reusable and easily transported even when dirty or wet. The placemat consists of a six-sided surface of waterproof flexible material forming the bottom, a same-shaped water resistant material forming a central layer, and a same-shaped absorbent material forming the top layer. Two straps are attached to the placemat; at the point of attachment the strap forms a loop, allowing the use of a pin or other implement to attach the mat to a soft surface. At the loose end of each strap is a pair of snaps, allowing the user to fasten the strap around an object in use by the child or baby to prevent the object from falling to the floor or ground. On the bottom of the mat is a pair of suction cups that allow the placemat to be attached to a hard surface where a pin would not be of use. The mat has two pairs of snaps located along the side edges at the proximal edge so a crumb catcher can be formed when the snaps are snapped together. When folded in the proper fashion, the placemat may be turned inside-out into a pocket located on the back of the mat, allowing for clean transportation without the need to clean the placemat beforehand. |
| US08771813B2 |
Biodegradable tube with restrictor portion
A container for semi-solid compositions comprising a tube portion having a first paper that defines first, second, and third plies forming an open end and a closed end, the tube portion comprising a lumen containing a semi-solid composition. The tube portion comprises a continuous coating that is a permeation barrier to the semi-solid composition, which is disposed between the first and second plies and the second and third plies. The container also includes a restrictor portion sized and dimensioned to couple with the open end of the tube portion and an end closure member sized and dimensioned to mate with the restrictor portion. The tube portion, restrictor portion, and end closure are made of one or more biodegradable materials. |
| US08771812B2 |
Paper and cardboard packaging with barrier coating
Described is paper or cardboard packaging produced from mineral oil contaminated, recycled paper, wherein the packaging includes a barrier layer obtainable by applying an aqueous polymeric dispersion comprising a copolymer obtainable by emulsion polymerization of C1-C4 alkyl(meth)acrylates, acid monomers, e.g., acrylic acid or methacrylic acid, 0-20 wt % of acrylonitrile and 0 to 10 wt % of further monomers, wherein the glass transition temperature of the copolymer is in the range from +10 to +45° C. The barrier layer may be situated on one of the surfaces of the packaging or form one of multiple layers of a multilayered packaging coating or be situated as a coating on one side of an inner bag situated within the packaging. |
| US08771809B2 |
Photoalignment material, display substrate having an alignment layer formed using the same, and method of manufacturing the display substrate
A photoalignment material includes a photoalignment polymer having a photosensitive portion represented by the following Chemical Formula 1, R1 represents a cyclic compound, each of R2 and R3 represents a single bond, —(CnH2n)—, —(CxH2x)O(CyH2y)—, or —(CaH2a)O(CbH2b)O(CdH2d)—, “n” represents an integer in the range of 1 to 6, each of “x”, “y”, “a”, “b”, and “d” represents 0 or an integer in the range of 1 to 6, x+y is an integer in the range of 1 to 5, and a+b+d is an integer in the range of 1 to 6. Each hydrogen atom is replaceable with —CH3, —CH2—CH3, —OCH3, —OCH2CH3, —OCH2OCH3, F, or Cl, and each hydrogen atom of —CH3, —CH2—CH3, —OCH3, —OCH2CH3, or —OCH2OCH3 is replaceable with F or Cl. |
| US08771804B2 |
Processes and systems for engineering a copper surface for selective metal deposition
The embodiments fill the need to enhance electro-migration performance, provide lower metal resistivity, and improve metal-to-metal interfacial adhesion for copper interconnects by providing improved processes and systems that produce an improved metal-to-metal interface, more specifically copper-to-cobalt-alloy interface. An exemplary method of preparing a substrate surface of a substrate to selectively deposit a thin layer of a cobalt-alloy material on a copper surface of a copper interconnect of the substrate in an integrated system to improve electromigration performance of the copper interconnect is provided. The method includes removing contaminants and metal oxides from the substrate surface in the integrated system, and reconditioning the substrate surface using a reducing environment after removing contaminants and metal oxides in the integrated system. The method also includes selectively depositing the thin layer of cobalt-alloy material on the copper surface of the copper interconnect in the integrated system after reconditioning the substrate surface. An exemplary system to practice the exemplary method described above is also provided. |
| US08771800B2 |
Method for the local application of chemical conversion layers
The present invention relates to a method for producing a chemical conversion layer on a metal surface, comprising the following method steps: (i) providing at least one cloth having a defined area, which is resistant at least in the pH range from 2 to 7 and is tear-proof in the wet state, (ii) bringing the cloth into contact with a liquid, which contains at least one active component for the formation of the chemical conversion layer, so that the cloth is impregnated with the liquid, (iii), applying the cloth impregnated with the liquid to a metal surface, and (iv) removing the cloth from the metal surface at a moment at which the cloth is still at least damp. |
| US08771799B2 |
Liquid delivery system
A system for spray delivery of liquids comprising a motor axially coupled to one or more pistons through a wobble plate coupling. Each piston feeds an input port of a swirl chamber spray nozzle. Each piston may separately pulse the swirl chamber using a different injection point. In one embodiment, the spray nozzle, swirl chamber, feed channels and cylinder heads for the cylinders may be formed as a single integrated casting. In one embodiment, the sprayer may include an intermediate plate rotatably mounted on the wobble plate. The sprayer may include a piston cap with a flat contact with the wobble plate/intermediate plate and a spherical interface with the piston. In a further embodiment, the system may be configured for handheld application of liquids and may comprise a tank for holding the liquid, a power source and control actuator together with the spray pump and nozzle in a hand operable package. |
| US08771794B2 |
Floor treatment procedure
A method for treating flooring not designed for sanding and having a multi-layer wax finish reduces the frequency of stripping the wax layers down to the flooring and recoating the flooring in carrying out periodic maintenance on the flooring. A mobile floor treating machine includes at least one rotating brush which is driven at a first circular speed x for cleaning the flooring and is driven at a second circular speed y for removing the two uppermost layers of wax, where y≧2x. The top remaining wax layer is then cleaned with the brush operating at the original circular speed x. Two layers of wax are then sequentially applied to the top remaining wax layer in replacing the two removed layers of wax on the floor and restoring the flooring to its original finish. The brush may be operated at 800-1500 RPM for burnishing and polishing. |
| US08771792B2 |
Method for manufacturing liquid discharge head
Provided is a method for manufacturing a liquid discharge head, the liquid discharge head includes a substrate provided on a surface with a first energy generating part and a second energy generating part for generating energy utilized for discharging a liquid; a first discharge port provided corresponding to the first energy generating part so as to face the surface; a second discharge port provided corresponding to the second energy generating part so as to face the surface; a first wall member which has a wall of a first liquid flow path which communicates with the first discharge port; and a second wall member which has a wall of a second liquid flow path which communicates the second discharge port, wherein a distance between the second energy generating part and the second discharge port is greater than a distance between the first energy generating part and the first discharge port. |
| US08771788B2 |
Conductive polymer film and polarizing plate using the same
A conductive polymer film having an antistatic function and an electromagnetic wave shielding function, and also having excellent optical properties such as transparency even if the film is arranged in the interior of LCD. The conductive polymer film comprises a polymer film and a conductive polymer adhered to the surface thereof, wherein the conductive polymer comprises polythiophene or polythiophene derivatives, the polymer film comprises an acetyl cellulose material or a norbornene material, a layer of the conductive polymer has a thickness of 3 μm or less, and the conductive polymer film has a visible light transmission of 78% or more and a surface resistivity of 103-1012 Ω/square. |
| US08771787B2 |
Ink for digital offset printing applications
An ink composition useful for digital offset printing applications comprises a colorant and a plurality of curable compounds. The compounds have Hansen solubility parameters as described herein, and the resulting ink composition is both compatible with certain dampening fluids and has certain rheological properties, including a low viscosity. |
| US08771786B2 |
Method for repair of a component of a turbomachine and a component repaired according to this method
A method is disclosed for the repair of a component of a turbomachine, in particular a rotor of an aircraft gas turbine, with blades taken up in at least one groove and with at least one support region for limiting a blade tilt angle, whereby at least one segment, which has been subjected to wear, of the support region of the component is removed, and a coating that can be introduced in the unit on at least one supporting surface of at least one blade is formed on the component for limiting the blade tilt angle. In addition, a component of a turbomachine, in particular a rotor of an aircraft gas turbine, with at least one such repair site is disclosed. |
| US08771785B2 |
Method for coating measurement
The present invention is directed to a method for obtaining characteristics of a target coating layer. Specifically, a clearcoat layer is provided over a target coating layer for measuring color and appearance characteristics of the target coating. The clearcoat layer can comprise materials from renewable resources. The present invention is also directed to a system for obtaining characteristics of the target coating layer. |
| US08771783B2 |
Implant and method for manufacturing same
An implant, in particular an intraluminal endoprosthesis, is provided having an implant body containing biodegradable metallic material, preferably iron. To accelerate the degradation, at least a portion of the surface of the implant body has a first coating formed from a composition containing at least one element selected from the group including strontium and calcium. An inexpensive method for manufacturing such an implant is also described. |
| US08771782B2 |
Implantable medical devices
The present invention is directed to methods for producing a coated substrate, including dissolving at least one biomolecule to form a solution; nebulizing the solution to form a liquid aerosol; combining the liquid aerosol and a plasma to form a coating; and depositing, in the absence of reactive monomers, the coating onto a substrate surface. In an aspect, the substrate can be an implantable medical device. |
| US08771773B2 |
Device and method for the high-pressure treatment of products
The present disclosure relates to a device for the high-pressure treatment of products, particularly of packaged foodstuffs. The device comprises a high-pressure chamber and a discharge valve for discharging high-pressure medium out of the high-pressure chamber. The invention is characterized in that a controllable actuator is provided for adjusting the rate of the pressure decrease in the high-pressure chamber at least over a predetermined pressure range. The disclosure also relates to a method for the high-pressure treatment of products, wherein pressure decrease takes place in a first phase and in a second phase, and the mean pressure decrease rate in the first phase is higher than in the second phase. |
| US08771770B1 |
Long life dough package
This invention relates to a packaging material for unbaked dough products which includes a container that is impermeable to water vapor transmission, a relative humidity control device in the container, dough, and a water permeable sheet forming a cover for the container wherein the relative humidity control device includes a water vapor permeable container containing a solidified humectant composition which further includes a humectant salt, water and carrier. |
| US08771769B2 |
Infused roasted seeds and methods of making thereof
Roasted infused seeds and a process for preparing roasted infused seeds are described. In one aspect, the roasted infused seeds may have salt, flavors, nutrients, colors, and/or functional ingredients as well as mixtures of these components infused internally into the seed. By infusing such components into the seeds, the methods described herein provide roasted seeds with unique flavors, nutrients, colors, textures, densities, and/or other functionalities. |
| US08771767B2 |
Microbiological reprocessing of degumming residue formed during biodiesel production
An industrial method of reprocessing degumming residue from the initial purification of natural fats as well as a feed additive, which may be produced using the said method. |
| US08771766B2 |
Genetic cluster of strains of Streptococcus thermophilus having unique rheological properties for dairy fermentation
The invention relates to a genetic cluster of strains of S. thermophilus, wherein the milk fermented with said strains is highly viscous and weakly ropy. The invention also relates to a genetic cluster of strains of S. thermophilus, wherein the genome of said strains comprises a CRISPR locus having the nucleotide sequence of SEQ ID No 1. |
| US08771764B2 |
Composition and method for improving vascular health
The present invention relates to a composition for the use in improving vascular health, including treating and preventing vascular diseases and diseases related thereto, using a botanical extract of oil palm vegetation liquor from the palm oil milling process. |
| US08771763B2 |
Composition for treating aids and associated conditions
An Aids and associated conditions related to Aids treating compositions is disclosed. The compositions comprise: a medicament selected from an extract of at least one of the following plant families: Apocynaceae (Pleioscarpa Bicarpellata); Annonaceae (Cleistopholis Patens); Dichapetalaceae (Dichapetehan Madagasca Riense); Annoceae (Uvaristrum Pierreanum); Cynocynaceae (Strophantus Gratus); Asclepiadaceae (Gongronema Latifolium); Combretaceae (Combretum Racemosum); Apocynaceae (Alostonia Boonei); Amaranthaceae (Alternanthera Pungens); Aroceae (Anchomanes Differmis); Cyperaceae (Seleria Voivinil); Anacardiaceae (Lannea Acida); Bignodaceae (Kigelia Africana); Bombacaceae (Ceiba Pentanota); Anarcardiaceae (Antrocaryon Micraster); Bombacaceae (Bombax Bounopozense): Anarcardiaceae (Spondias Mombin); Caricaceae (Carica Papaya); a glyceryl ester of any of the foregoing extracts; a saponin of any of the foregoing extracts; an alkaloid of any of the foregoing extracts; a protein of any of the foregoing extracts; a fat of any of the foregoing extracts; a sugar of any of the foregoing extracts; and any mixture of any of the foregoing. |
| US08771757B2 |
Method for the preparation of a silicic acid comprising extrudate, said extrudate, its use and a pharmaceutical composition comprising the said extrudate
The invention relates to a method for the preparation of a silicic acid comprising extrudate, comprising the steps of: i) forming of stabilized silicic acid, by hydrolysing a silicon compound into orthosilicic acid and/or oligomers thereof in the presence of a stabilizing agent, which is a quaternary ammonium compound, or an amino-acid, or an amino acid source or combinations thereof; ii) mixing of the stabilized silicic acid with a carrier in an amount upto the loading capacity of the carrier for silicic acid; and iii) extruding the resulting mixture thereby forming the extrudate, to extrudates obtainable with the method, to an extrudate for use in the production of animal feed, feed supplement, human food and/or food supplement and of a pharmaceutical or cosmetic preparation, and for the treatment of infections, nails, hair, skin, teeth, collagen, connective tissue, bones, osteopenia, cell generation and degenerative (ageing) processes, and to a pharmaceutical composition comprising an extrudate. |
| US08771750B2 |
Delivery or removal of metals from biological systems
A process for delivering and/or removing metal from a biological system by loading a titanate sorbent with a biometal either before introduction into the system for delivery to a site within the system or after introduction into the system for delivery to a site where there is an excess accumulation of metal and thereafter the sorbent is loaded at the site with the excess metal and is removed from the system. |
| US08771745B2 |
Prostaglandin and prostamide drug delivery systems and intraocular therapeutic uses thereof
Biocompatible, bioerodible implants and microspheres include latanoprost and a biodegradable polymer effective, when placed intraocular (such as into the subtenon space) to treat glaucoma. |
| US08771744B2 |
Barrier composition
The invention provides a process for increasing the crystallinity of at least one solid material which is less than 100% crystalline, comprising applying ultrasound to the substantially dry solid material. |
| US08771742B2 |
Porous cellulose aggregate and molding composition thereof
A porous cellulose aggregate characterized by having a secondary aggregate structure resulting from aggregation of primary cellulose particles, having a pore volume within a particle of 0.265 to 2.625 cm3/g, containing I-type crystals and having an average particle size of over 30 to 250 μm, a specific surface area of 0.1 to less than 20 m2/g, a repose angle of 25° to less than 44° and a swelling degree of 5% or more, and characterized by having the property of disintegrating in water. |
| US08771738B2 |
Polysaccharide-based polymer tissue adhesive for medical use
Method of forming tissue adhesives by reacting an oxidized polysaccharide with a water-dispersible multi-arm polyether amine, wherein at least three of the arms are terminated by primary amine groups, are disclosed. The use of the tissue adhesives for medical and veterinary applications such as topical wound closure; and surgical procedures, such as intestinal anastomosis, vascular anastomosis, tissue repair, and ophthalmic procedures; drug delivery; anti-adhesive applications; and as a bulking agent to treat urinary incontinence are described. |
| US08771733B2 |
Pharmaceutical composition containing an anti-nucleating agent
Pharmaceutical compositions suitable for oral administration in solid dosage forms are described. The compositions comprise an effective amount of a drug compound in the form of a salt, wherein the drug salt is characterized by conversion to a less soluble form of the drug compound under certain pH conditions, and an anti-nucleating agent. |
| US08771731B2 |
Antimicrobial nanoemulsion compositions and methods
The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs. |
| US08771730B2 |
Carbidopa/Levodopa gastroretentive drug delivery
A gastroretentive drug formulation for the sustained release of an active agent in the gastrointestinal tract comprises an internal layer or compartment comprising an active agent and one or more pharmaceutical excipients, of which at least one is a polymer and two membranes forming together an envelope around the inner membrane, each membrane comprising at least one polymeric combination of an enteric polymer which is not soluble in gastric juice, and an hydrophilic swelling polymer, and at least one plasticizer. |
| US08771723B2 |
Compositions for reducing gastro-intestinal methanogenesis in ruminants
The present invention concerns the reduction of gastro-intestinal methanogenesis in ruminants with the aid of agents that compete for the hydrogen atoms required by methanogens during normal fermentation of ingested feed. The invention in one aspect resides in the findings that both nitrate reductive pathways as well as sulphate reductive pathways outcompete gastro-intestinal methanogenesis in ruminants and, that the methanogenesis reducing effects of nitrate and sulphate are completely additive. At the same time the combined administration of nitrate and sulphate was found to be fully effective to avoid or mitigate the potential problems of nitrite intoxication normally encountered when using nitrate alone, which effect is further enhanced, where necessary, by the addition of a nitrite reducing probiotic micoroorganism. Hence, products are provided comprising high amounts of a combination of a nitrate compound and a sulphate compound and optionally a nitrite reducing probiotic microorganism, as well as methods of reducing gastro-intestinal methanogenesis in ruminants using such compositions. |
| US08771720B2 |
Medical device comprising polyhydroxyalkanoate having pyrogen removed using oxidizing agent
Polyhydroxyalkanoates (PHAs) from which pyrogen has been removed are provided. PHAs which have been chemically modified to enhance physical and/or chemical properties, for targeting or to modify biodegradability or clearance by the reticuloendothelial system (RES), are described. Methods for depyrogenating PHA polymers prepared by bacterial fermentation processes are also provided, wherein pyrogens are removed from the polymers without adversely impacting the polymers' inherent chemical structures and physical properties. PHAs with advantageous processing characteristics, including low melting points and/or solubility in non-toxic solvents, are also described. The PHAs are suitable for use in in vivo applications such as in tissue coatings, stents, sutures, tubing, bone, other prostheses, bone or tissue cements, tissue regeneration devices, wound dressings, drug delivery, and for diagnostic and prophylactic uses. |
| US08771713B2 |
Method and process for the production of multi-coated recognitive and releasing systems
The present invention includes compositions, methods, systems for the controlled delivery of an active agent in a tablet polymer comprising two or more layers, wherein each of the two or more layers comprises at least one active agent and at least one molecular recognition polymer, wherein the two or more layers are compressed into a single tablet. |
| US08771712B2 |
Topical administration of acyclovir
The present invention provides a topical composition comprising (a) at least one delivery agent compound and (b) a acyclovir compound. Methods of treatment, and methods of preparing the topical composition are also provided. |
| US08771704B2 |
Dengue vaccine, pharmaceutical composition comprising the same, nucleotide sequence and antibody composition
The present invention relates to a dengue vaccine, a pharmaceutical composition comprising the same, a nucleotide sequence, and an antibody composition. The dengue vaccine of the present invention includes chimeric nonstructural protein 1, which comprises N-terminus of DV NS1 from amino-acid residues 1 to 270 and C-terminus of JEV NS1 from amino-acid residues 271 to 352 (designated DJ NS1). Therefore, the dengue vaccine without autoimmunity according to the present invention is able to avoid cross-reactions with endothelial cells and platelets, and is able to shorten the bleeding time. |
| US08771699B2 |
Magnetic transducers
Embodiments herein relate to the production of biocompatible magnetic nanoparticles with a high SAR-value which produce a large amount of heat when exposed to an alternating magnetic field. The produced heat can be used among others for therapeutic purposes, in particular for combating cancer. |
| US08771694B2 |
Immunoconjugates and humanized antibodies specific for B-cell lymphoma and leukemia cells
A chimeric LL2 monoclonal antibody (mAb) is described in which the variable regions of the murine LL2 mAb are recombinantly joined to the human constant region domains, which retains the immunospecificity and B-cell lymphoma and leukemia cell internalization capacity of the murine LL2 (mAB), and which exhibits reduced human anti-mouse antibody production activity (HAMA). A humanized LL2 mAb is described in which the CDRs are recombinantly joined to a framework sequence of human variable regions, and subsequently linked to human constant region domains, which retains the immunospecificity and B-lymphoma and leukemia cell internalization capacities of the murine and chimeric LL2 mABs, and has the potential for exhibiting reduced HAMA. Isolated DNAs encoding the LL2 variable and CDR framework regions are described. Conjugates of chimeric and humanized chimeric LL2 antibodies with cytotoxic agents or labels find use in therapy and diagnosis of B-cell lymphomas and leukemias. |
| US08771685B2 |
Anti-BV8 antibodies and uses thereof
The present invention concerns antibodies to Bv8 and the uses of same. |
| US08771683B2 |
Therapeutic apyrase constructs, apyrase agents, and production methods
This invention provides a new class of enhanced apyrases (EN-apyrases) with superior pharmacokinetic, pharmacodynamic, and pharmacochemical properties and which can be purified using simplified procedures. The invention further provides constructs for transforming a cell to produce these EN-apyrases. The EN-apyrase construct comprises sequences encoding a signal sequence, a linker, and a soluble apyrase. Also provided are preparations of apyrases and methods for producing apyrase in culture cells and purification thereof. |
| US08771681B2 |
Methods and compositions for protecting and treating muscarinic receptors by administering a pyrophosphate analog to a subject exposed to bacterial, fungal, viral, prion or algal infection
Methods and compositions for protecting and treating a muscarinic receptor in an animal or plant from bacterial, fungal, algo or algae infections through administration of at least one pyrophosphate analog. |
| US08771679B2 |
Prodrug activation in cancer cells using molecular switches
The present invention features a novel protein engineering strategy by combining the domains of two independent proteins into a molecular switch. The invention features polypeptides comprising a prodrug activating enzyme and a protein that binds a cancer specific marker, polynucleotides encoding the polypeptides, and molecular switches for converting a prodrug into a toxin, comprising the polypeptides. The invention also features methods for converting a prodrug into a toxin, methods for treating cancer, and methods for making the molecular switches, as well as kits. |
| US08771677B2 |
Colony-forming unit cell of human chorion and method to obtain and use thereof
The present invention features colony-forming unit cells derived from the chorion of human placenta and describes compositions and methods for the uses of chorionic cells and their products for therapeutic purposes based upon production and release of multiple growth factors and cytokines by these cells stimulating tissue regeneration independent of engraftment, as well as differentiation into a specific cell type. |
| US08771674B2 |
Oligosaccharide composition for treating skin diseases
The invention discloses a composition comprising at least one N-acetyl-lactosamine, at least one sialylated oligosaccharide and at least one fucosylated oligosaccharide, for use in the prevention and/or treatment of skin conditions and skin diseases. Preferably said composition is a starter infant formula. Said skin disease is in particular atopic dermatitis. |
| US08771673B2 |
Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions
A method of combating rheumatoid arthritis, comprising administering to a human subject in need thereof, an effective oral dose of a probiotic composition in an oral dose form including, as the only bacterial species therein, the bacterial species of Bacillus subtilis, Bacillus coagulans, and Enterococcus faecium. The initial occurrence, and progress of remission of the rheumatoid arthritis condition incident to such probiotic therapy, may be established and monitored by assay of rheumatoid factor and/or anti-CCP antibodies present in a blood sample of the human subject. |
| US08771664B2 |
Compositions comprising apolipoprotein A polypeptide and interleukin 15, and methods of treatment using the same
The present invention relates to compositions capable of promoting both the innate immune response as well as the adaptive immune response in a subject based on the jointly use of ApoA, interleukin 15 and the Sushi domain of the IL15 receptor alpha chain, as well as to the use of these compositions for the stimulation of the immune response in a patient and to therapeutic methods for the treatment of infectious and neoplastic diseases. |
| US08771663B2 |
Formulation having mobilising activity
The present innovation relates to a novel formulation capable of increasing the amount of stem cells and progenitor cells in circulation in the peripheral blood of a mammal; the formulation is characterized in that it contains defibrotide in combination with at least one haematopoietic factor having the capacity to mobilize haematopoietic progenitors, preferably G-CSF. In one embodiment, the formulation includes two separately administrable formulations, one containing a haematopoietic factor having the capacity to mobilize haematopoietic progenitors and the other containing defibrotide. The formulation is effective to achieve an increase in the number of haematopoietic progenitor cells that is greater than an increase in the number of haematopoietic progenitor cells achieved by the haematopoietic factor alone. |
| US08771660B2 |
Method of screening for a damp-dry malodor inhibitor and method of evaluating damp-dry malodor inhibitor by microbial production of 4-methyl-3-hexenoic acid
A method of screening a damp-dry malodor inhibitor, containing the steps of: bringing microorganisms having a 4-methyl-3-hexenoic acid production capacity into contact with a test substance in the presence of a sebaceous dirt component, detecting the production of a damp-dry malodor-causing substance by the microorganisms, and thereby selecting a test substance having a damp-dry malodor inhibitory function; and a method of evaluating a damp-dry malodor inhibitor, containing the steps of: bringing microorganisms having a 4-methyl-3-hexenoic acid production capacity into contact with a test substance in the presence of a sebaceous dirt component, detecting the production of a damp-dry malodor-causing substance by the microorganisms, and thereby evaluating the damp-dry malodor inhibitory function of the test substance. |
| US08771659B2 |
Cosmetic compositions comprising at least one starch and at least one peg fatty diester, and uses thereof
The present disclosure relates to novel cosmetic compositions comprising, in a cosmetically acceptable aqueous medium: from 0.1% to 2% by weight of at least one starch, and from 0.1% to 1% by weight, relative to the total weight of the composition, of at least one diester of a carboxylic acid comprising 8 to 30 carbon atoms and of polyethylene glycol. The cosmetic compositions provides a fondant texture, and these compositions rinse out easily. Hair treated with this composition has a soft feel, free of residue. These compositions are may be used for washing and/or conditioning keratin materials such as the hair or the skin. |
| US08771658B2 |
Compositions and methods for treating keratin based fibers
Compositions, formulations, kits and methods for temporarily or semi-permanently transforming the shape of individual hair filaments or keratinous fibers (curling, waving or straightening) by applying no heat or heat below about 300° F. to prevent damage to the keratinous fibers. |
| US08771656B2 |
Long-lasting easy wash-off cosmetic compositions
Cosmetic compositions are provided, which are capable of forming a cosmetic film on a human integument when applied thereto. Cosmetic compositions according to the invention typically include a cosmetically acceptable vehicle, optionally, one or more colorants, and a pH-dependent film-forming polymer of poly(methacrylic acid-co-methyl methacrylate) having a ratio of methacrylic acid to methyl methacrylate of about 1:1 to about 1:2, an acid value of from about 150 to about 350 mg KOH/g, and a weight average molar mass between about 100,000 and about 150,000 g/mol. The compositions are capable of forming an adherent film on the integument that is substantially resistant to removal by water at a first pH, but readily dispersible or soluble in water at a second pH higher than said first pH. |
| US08771651B2 |
Mouth rinses and tooth sensitivity treatment compositions
The present invention relates to tooth sensitivity treatment compositions, including mouth rinses, comprising C2-C5 diacid, triacid or tetraacid salts and a tastemasking agent(s). Methods for using the compositions are also disclosed. |
| US08771650B2 |
Inducible release vehicles
This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in an applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing anti-caries or flavoring compounds and for pharmaceutical and/or nutraceutical applications. |
| US08771646B2 |
Nicotinic acid and picolinic acid derived near-infrared fluorophores
This invention relates to new fluorescent chemical entities, including fluorescent molecules that comprise a carboxyl or carbonyl functionalized pyridine moiety. This invention also relates to the corresponding reactive versions of such molecules. This invention also relates to the corresponding conjugates with moieties such as peptides, proteins, various biomolecules, carbocyclic and heterocyclic compounds, sugars, and their uses thereof. |
| US08771645B2 |
Composition comprising a cell death marker and a wavelength-optimized label
The invention relates to the use of a cell death marker labelled with a wavelength-optimised label for identifying cell death in the eye. Suitable cell death markers are the Annexins and fragments and derivatives thereof. The invention also relates to a pharmaceutical composition comprising a cell death marker labelled with a wavelength-optimised label and a method for monitoring cell death in the eye using a cell death marker labelled with a wavelength-optimised label. |
| US08771642B2 |
Active particles for bio-analytical applications and methods for their preparation
Nanoparticles, which are luminescent and/or electroactive and/or suitable for MRI (magnetic resonance imaging and/or PET (positron emission tomography) applications, comprise a micelle, which has a hydrophilic shell and an hydrophobic central portion, and a polysilicate core; the micelle comprises a plurality of molecules of a functionalized surfactant having the following structure: M1-Hydro1-Lipo-Hydro2-M2 wherein Lipo indicates a hydrophobic chain; Hydro1 ed Hydro2 indicate, each, a respective hydrophilic chain; M1 ed M2 represent respective recognition functionalities. |
| US08771641B2 |
Aryloxyanilide imaging agents
The present invention provides a novel radiolabeled aryloxyalinine derivative suitable for in vivo imaging. In comparison to known aryloxyalinine derivative in vivo imaging agents, the in vivo imaging agent of the present invention has better properties for in vivo imaging. The in vivo imaging agent of the present invention demonstrates good selective binding to the peripheral benzodiazepine receptor (PBR), in combination with good brain uptake and in vivo kinetics following administration to a subject. |
| US08771638B2 |
Method and apparatus for sequestering carbon dioxide from a spent gas
A method and apparatus for sequestering carbon dioxide from a waste gas and reusing it as a recycled gas without emissions concerns, including: given a gas source divided into a process gas and a waste gas: mixing the process gas with a hydrocarbon and feeding a resulting feed gas into a reformer for reforming the feed gas and forming a reducing gas; and feeding at least a portion of the waste gas into a carbon dioxide scrubber for removing at least some carbon dioxide from the waste gas and forming a carbon dioxide lean gas that is mixed with the reducing gas. Optionally, the method also includes feeding at least a portion of the waste gas into the carbon dioxide scrubber for removing at least some carbon dioxide from the waste gas and forming a fuel gas after the addition of a hydrocarbon that is fed into the reformer. Optionally, the gas source and the reducing gas are associated with a direct reduction process for converting iron oxide to metallic iron in a reduction furnace that utilizes the reducing gas, optionally after some modification, and produces the gas source. |
| US08771637B2 |
Gas separation process for production of hydrogen by autothermal reforming of natural gas, with carbon dioxide recovery
Disclosed herein is a process for the production of hydrogen by autothermal reforming of natural gas, with simultaneous recovery of carbon dioxide using carbon dioxide-selective membrane separation. Residual gas from the hydrogen and carbon dioxide recovery is recycled back to the autothermal reformer. |
| US08771634B1 |
Generation of hydrogen gas from a borohydride at a constant temperature using the phase transition of a hydrate
The present subject matter provides heat management while generating hydrogen gas from a hydride achieved by coupling a hydride with a hydrate. The present subject matter unexpectedly provides improved methods so that the heat released by the hydride during hydrolysis is accurately balanced by the heat absorbed by the hydrate as the hydrate undergoes a phase transition to a less hydrated or to an anhydrous form. Examples of heat-moderated hydrogen generating systems are provided, and include, among others: NaBH4/Na2SO4.10H2O, NaBH4/CoSO4.7H2O, and NaBH4/FeSO4.7H2O. The subject matter provides a methodology for determining the correct proportions of hydride/hydrate to use in preparing a hydrogen generator capable of operating at a nearly constant temperature at or near a phase transition temperature of the hydrate or at a higher temperature that is still within a desired temperature range, such as, for example, 30-90° C. |
| US08771631B2 |
Method for producing perovskite type composite oxide
A method is provided which includes a reaction step of reacting at least titanium oxide, a calcium compound, and barium hydroxide in a slurry solution so as to produce a perovskite-type composite oxide. The perovskite-type composite oxide is represented by (Ba1-xCax)mTiO3, and x is within a range of 0 |
| US08771628B2 |
Aqueous carbon nanotube applicator liquids and methods for producing applicator liquids thereof
Certain applicator liquids and method of making the applicator liquids are described. The applicator liquids can be used to form nanotube films or fabrics of controlled properties. An applicator liquid for preparation of a nanotube film or fabric includes a controlled concentration of nanotubes dispersed in a liquid medium containing water. The controlled concentration is sufficient to form a nanotube fabric or film of preselected density and uniformity. |
| US08771626B2 |
Process for purifying perfluorinated products
This invention relates to a process for purifying at least one of perfluoromethane and nitrogen trifluoride from a mixture thereof using an ionic liquid. The process may be performed by a technique such as extractive distillation or absorption wherein at least one ionic liquid is used as the entraining agent or absorbent, respectively. |
| US08771625B2 |
Method for reducing nitric oxide in the exhaust gas flow of internal combustion engines
A method is described for reducing nitrogen oxides in the exhaust gas flow of combustion engines, especially a motor vehicle internal combustion engine, wherein an air/fuel mixture in the combustion chamber of the combustion engine is combusted in the presence of a fuel additive and, in the process, the fuel additive decomposes and the exhaust gas flow is guided through at least one catalyst arranged downstream of the combustion chamber. This method is characterized in that a fuel additive is used, which decomposes in the combustion chamber releasing ammonia and the exhaust gas flow containing ammonia is guided through at least one SCR catalyst arranged downstream of the combustion chamber to reduce the concentration of the nitrogen oxides contained therein. The method according to the invention is highly effective in reducing the nitrogen oxide content in the exhaust gas flow of a combustion engine without an exhaust gas aftertreatment system having to be expensively formed and the installation space having to be increased. |
| US08771624B2 |
Catalyst for purifying exhaust gas from internal combustion engine and process for purifying exhaust gas using the same
An Object of the patent is to remove highly reducing hydrocarbon exhausted during acceleration period, and to remove efficiently hydrocarbon even after contacting with highly reducing hydrocarbon. By using a catalyst having a higher proportion of palladium having surface charge of 2-valence or 4-valence supported than that of 0-valence by supporting palladium together with magnesium oxide, hydrocarbon exhausted from an internal combustion engine especially during acceleration period can be efficiently removed. |
| US08771623B2 |
Methods and apparatus for residual material management
Residual impurity reduction methods and apparatus are provided. A method comprises conducting a gaseous stream through an unlined portion of a pipe, wherein the gaseous stream comprises sodium and wherein the unlined portion of the pipe is at least about eighteen inches long, injecting a neutralizing agent into the gaseous stream at an injection point, wherein the injection point is located at a point where the sodium is in at least a partially condensed state. The gaseous stream is conducted through a heated portion of a pipe and a cooled portion of a pipe. In addition, methods and apparatus may include a trap system for use with a carbonization furnace. |
| US08771621B2 |
Recovery method for a continuous calcium extraction and PCC production
A method of mineralizing calcium from industrial waste comprising extracting calcium ions from a suspension of calcium rich granular particles and aqueous ammonium nitrate to form a calcium-rich first fraction and a heavy second fraction. The heavy second fraction is separated from the first fraction and the calcium-rich first fraction is carbonated with a gas comprising carbon dioxide to form a suspension of precipitated calcium carbonate and aqueous ammonium nitrate. The precipitate is separated from the aqueous ammonium nitrate by centrifugal means and the separated heavy second fraction comprises an enriched weight percent of iron. |
| US08771616B2 |
Method and apparatus for carbonylating methanol with acetic acid enriched flash stream
A carbonylation process for producing acetic acid including: (a) carbonylating methanol or its reactive derivatives in the presence of a Group VIII metal catalyst and methyl iodide promoter to produce a liquid reaction mixture including acetic acid, water, methyl acetate and methyl iodide; (b) feeding the liquid reaction mixture at a feed temperature to a flash vessel which is maintained at a reduced pressure; (c) heating the flash vessel while concurrently flashing the reaction mixture to produce a crude product vapor stream, wherein the reaction mixture is selected and the flow rate of the reaction mixture fed to the flash vessel as well as the amount of heat supplied to the flash vessel is controlled such that the temperature of the crude product vapor stream is maintained at a temperature less than 90° F. cooler than the feed temperature of the liquid reaction mixture to the flasher and the concentration of acetic acid in the crude product vapor stream is greater than 70% by weight of the crude product vapor stream. |
| US08771614B2 |
Method for processing a fluid and fluid processing device
The present invention relates to improved methods for processing fluids and to a fluid processing device (1) for use in a centrifuge comprising: (a) a first holder (14) form-fit to the shape of a first tube (18) for holding said first tube (18) whereby said first tube (18) has a first cross section (A1); and (b) a second holder (22) form-fit to the shape of a second tube (26) for holding said second tube (26) whereby said second tube (26) has a second cross section (A2) that is different from said first cross section (A1). With the fluid processing devices and the methods according to the invention, it is possible to simplify the centrifugal processing steps for a given fluid processing sequence and to automate them. |
| US08771612B2 |
Photoresponsive gas-generating material, micropump and microfluid device
The present invention provides a photoresponsive gas-generating material that is to be used in a micropump of a microfluid device having fine channels formed therein, and is capable of effectively generating gases for transporting a microfluid in response to light irradiation and transporting the microfluid at an improved transport efficiency. The present invention also provides a micropump incorporating the photoresponsive gas-generating material.A photoresponsive gas-generating material 13 is to be used in a micropump having fine channels formed in a substrate, and comprises a photo-sensitive acid-generating agent and an acid-sensitive gas-generating agent, and a micropump 10 has the photoresponsive gas-generating material 13 housed therein. |
| US08771609B2 |
Module for processing a biological sample, biochip kit, and use of the module
A module for processing a biological sample for an analysis test is disclosed. The processing module includes, in at least one embodiment, an interface at which the processing module can be connected to a cartridge with a lab-on-a-chip, in which cartridge the analysis steps are carried out. A biochip kit is also disclosed. In at least one embodiment, the biochip kit includes one or more processing modules which are intended for different sample materials and which can be connected to the same cartridge type. |
| US08771606B2 |
Kitchen waste bin
A kitchen waste bin having a casing; a lid hingedly attached to the casing and moveable between open and closed positions. The lid includes an outer casing, an inner casing and a cavity there between. The inner casing having one or more apertures communicating between the cavity and the interior of the receptacle when the lid is closed; an ozone generator located within the cavity arranged to discharge ozone into the receptacle where the ozone generator is an ultraviolet source that includes an elongate lamp in an elongate channel shaped reflector; a switch that generates and transmits a control signal when the lid is moved; and a control unit arranged to switch the ozone generator on or off in response to a control signal. Ozone is discharged into the receptacle for a sterilization period when the lid is closed. Discharge of the ozone stops when the lid is opened. |
| US08771605B2 |
High shear system for the production of chlorobenzene
Use of a high shear mechanical device incorporated into a process for the production of chlorobenzene is capable of decreasing mass transfer limitations, thereby enhancing the chlorobenzene production process. A system for the production of chlorobenzene from benzene and chlorine, the system comprising a reactor and an external high shear device, the outlet of which is fluidly connected to the inlet of the reactor; the high shear device capable of providing an emulsion of chlorine gas bubbles within liquid benzene. |