Document Document Title
US08760130B2 Electronic apparatus and power supply device that switch between on-state and off-state
The electronic apparatus includes a direct-current voltage generation part that generates a direct-current voltage from a commercial power supply; a switching part that switches between an on-state in which the direct-current voltage from the direct-current voltage generation part is output, and an off-state in which the output of the direct-current voltage is shut down, a control part that controls operation of the direct-current voltage generation part; and a power supply maintaining part connected to the direct-current voltage generation part, the power supply maintaining part instructing the switching part to be in the on-state or the off-state, and consequently, enables provision of a soft-switch electronic apparatus that after recovery of a power failure, automatically returns to a state before occurrence of the power failure.
US08760124B2 Systems and methods for initializing a charging system
Systems and methods are provided for initiating a charging system. The method, for example, may include, but is not limited to, providing, by the charging system, an incrementally increasing voltage to a battery up to a first predetermined threshold while the energy conversion module has a zero-percent duty cycle, providing, by the charging system, an incrementally increasing voltage to the battery from an initial voltage level of the battery up to a peak voltage of a voltage source while the energy conversion module has a zero-percent duty cycle, and providing, by the charging system, an incrementally increasing voltage to the battery by incrementally increasing the duty cycle of the energy conversion module.
US08760123B2 High voltage dedicated charging port
Circuitry in an electronic device may be attached to external device, such as a power supply, to receive a voltage at a desired voltage level from the external device. The circuitry may assert one of several electrical configurations on the cabling that electrically connects the portable device to the external device to indicate to the external device a desired voltage level.
US08760117B2 Portable communication apparatus
A battery pack has a case for storing a battery can, and a metal plane made of a conductive material and connected to the battery can in high frequency is provided on the outer circumference plane of the case. A mounting recessed part for removably mounting the battery pack is provided, and a printed circuit board is provided inside. In the mounting recessed part, a plurality of grounding terminals are electrically connected to a grounding layer of the printed circuit board, on an inner plane to which the metal plane of the battery pack abuts. When the battery pack is mounted in the mounting recessed part, electricity is carried between the metal plane and the grounding terminals, and the metal plane and the battery can are grounded to the grounding layer of the printed circuit board in high frequency.
US08760115B2 Method for charging a plug-in electric vehicle
A system and method for charging a plug-in electric vehicle with an external power source, even when the overall power requested by the plug-in electric vehicle exceeds the overall power available from the external power source. In an exemplary embodiment, a method determines the overall power requested by one or more vehicle systems, and then compares that to the overall available power from the external power source. If the overall requested power exceeds the overall available power, then the power from the external power source is allocated or apportioned to the different vehicle systems according to an allocation process that may consider factors like predetermined priorities and current vehicle conditions.
US08760110B2 Electricity distribution system and electricity distribution method
An electricity distribution system includes an electricity supply control unit that receives information on power consumption, estimates the current and the future power consumption, and controls the supply of electricity to the electric device; an information display unit that displays information on a power use situation of an electric device electrically connected with the electricity supply control unit; and a battery server that accumulates power, in which the electricity supply control unit communicates the information on the power consumption with a new electric device when the new electric device is electrically connected, and when the amount of available power is exceeded by supplying electricity to the electric device, does not supply electricity to the electric device, makes the information display unit display that the amount of available power is exceeded by supplying electricity to the information display unit, and determines whether to use the power accumulated in the battery server.
US08760104B2 Determining average current drawn by a motor
A method of determining the average current drawn by an electric motor, the motor comprising a plurality of phases, the method comprising: driving each phase of the motor with cyclic pulse width modulated drive signals having a first state and a second state, and a duty ratio indicative of the ratio of time spent in the first to second states within a cycle, determining the current flowing through each phase at an instant in the cycle; and determining the average current drawn by the motor over at least one cycle by combining the currents flowing through each phase with the duty ratios for each phase. The method may be embodied in a combination of a motor and a drive circuit for the motor, such as can be used in an Electric Power Assisted Steering system.
US08760103B2 Actuator power control circuit having fail-safe bypass switching
A system for controlling power to actuators. For example, a controller may output a signal having a variable duty cycle waveform for controlling current to an actuator via an interface circuit between the controller and the actuator. Changing the duty cycle may change the amount of current to the actuator. The controller may provide a control signal that optimizes power consumption by the actuator for efficiency purposes. However, if the controller fails, then no control signal may be available to allow current to the actuator, particularly in situations where the actuator may need to be operationally tested. To avoid such situations, fail-safe bypass switching may be incorporated into the interface circuit. Upon absence of a control signal from the controller, the circuit may provide a default signal in lieu of the control signal to maintain current to the actuator.
US08760102B2 Electric power tool
In an impact driver, a link unit (a link sleeve and first and second elongated protrusions) is provided between the mode switching ring for selecting an operation mode and the slide button for selecting the rotation speed. With the link unit, a switching operation of a slide button to the high-speed side is performed in coordination with a selecting operation of a mode switching ring to an impact mode or a vibration drill mode and the rotation speed is held at high speed.
US08760099B2 Sensorless motor apparatus, back EMF detector and detection method thereof
A back electromotive force (EMF) detector for a motor is disclosed. The back EMF detector includes an upper switch, a lower switch, a current sensing resistor and a first to third resistance providers. The upper and lower switches are controlled by a first and a second control signal respectively. The current sensing resistor coupled between the lower switch and a reference ground voltage. A first terminal of the first resistance provider coupled to the upper switch, and a back EMF detection result is generated at a second terminal of the first resistance provider. The second resistance provider coupled between the reference ground voltage and the first resistance provider. The third resistance provider is coupled between the coupled terminal of the first and second resistance provider and the lower switch. Wherein, the first to the third resistance providers are determined by at least one characteristic parameter of the motor.
US08760096B2 Control apparatus for power conversion system including DC/AC converter connected between electric rotating machine and DC power source
A control apparatus is for use in a power conversion system including a DC/AC converter circuit connected to an electric rotating machine at output terminals thereof and to a DC power source at input terminals thereof through a switching means, a capacitor being connected across the input terminals of the DC/AC converter circuit. The control apparatus includes a current supply means configured to perform current supply control to supply a current to the electric rotating machine in order to discharge the capacitor by manipulating the DC/AC converter circuit in a state where the switching means is set open, and a speed lowering means configured to apply a brake force to a rotating shaft of the electric rotating machine to reduce a rotational speed of the electric rotating machine prior to the current supply control being performed by the current supply means if the rotational speed exceeds a specified speed.
US08760093B2 Electronic control apparatus for a vehicle
An electronic control apparatus for a vehicle, which operates a power conversion circuit connected to a rotating machine used as an in-vehicle traction unit to control controlled variables of the rotating machine, includes a controlling arithmetic processing unit which performs arithmetic processing to control the controlled variables of the rotating machine, and a monitoring arithmetic processing unit which monitors the controlling arithmetic processing unit. The monitoring arithmetic processing unit includes an on-monitoring prohibition unit which prohibits outputting an operation signal from the controlling arithmetic processing unit to the power conversion circuit until the controlling arithmetic processing unit is confirmed to be in a normal condition.
US08760091B2 Multifunction PMDC motor apparatus and method thereof
A control circuit for a PMDC motor used in an ice delivery apparatus, the circuit including a double pole double throw relay that switches both sides of the circuit and peripheral circuitry connected between a power source and the double pole double throw relay to rectify the power source and power the PMDC motor.
US08760088B2 Electromagnetism-torque friction-balancing truckle for mobile medical devices
A truckle for a mobile medical device is provided. The truckle includes at least one electromagnetism torque balancing motor mounted on the truckle and configured to balance out friction generated by the truckle.
US08760087B2 Energy-efficient actuator system
What is described is an actuator system (2) comprising at least one actuator (29, 29′) and an associated control system (8) which is designed for at least two operating modes, at least one of which may be deactivated, whereby one of the operating modes is a high efficiency operating mode.
US08760083B2 Ballast with control device for controlling the open-circuit voltage
A ballast which controls the open-circuit voltage of the ballast. The ballast includes a power factor corrector (PFC) for receiving an AC input voltage and converting the AC input voltage into a power factor corrected DC voltage; a DC/DC converter connected to the PFC and having a switch placed at a low-voltage side of the DC/DC converter for converting the DC voltage of the PFC into a DC output voltage according to the switching operation of the switch; a controller connected to a control terminal of the switch of the DC/DC converter for sending a switching control signal to control the switch; and an open-circuit voltage controller for detecting a voltage associated with the open-circuit voltage of the ballast and regulating the duty ratio or pulse density or switching frequency of the switching control signal in response to the results of the detection, thereby controlling the open-circuit voltage.
US08760081B2 Systems and methods for backlight driving
Various systems and methods for LCD backlight control are disclosed herein. For example, some embodiments of the present invention provide an LCD backlight circuit with an analog inverter circuit that provides a drive voltage to a lamp. A current traversing the lamp is sensed and provided to a digital control circuit. Based on the sensed current, the digital control circuit generates a control signal that is fed back to the analog inverter circuit. In some cases, the digital control circuit is used to cause a gradual increase in voltage applied to the lamp to achieve ignition of the lamp. In other cases, the digital control is used to provide a pre-distorted sine wave that attenuates one or more harmonics introduced into the system by the non-linearities of the lamp.
US08760077B2 Plant illumination apparatus
A plant illumination apparatus includes a light source module including a first light source and a second light source generating lights having different wavelengths, an environment-detecting module detecting an external environment to obtain a real-time environment parameter, and a control module connected to the light source module and the environment-detecting module. The control module includes a processor unit and a storage unit storing a database of plant growing environment parameters. The processor unit loads at least one preset growing environment parameter corresponding to a plant growth timing from the database of plant growing environment parameters, and compares the preset growing environment parameter with the real-time environment parameter to output at least one comparison result. The processor unit adjusts the first light source and the second light source according to the comparison result, so that an adjusted environment parameter matches the preset growing environment parameter.
US08760075B1 Illumination device control systems and methods
In various embodiments, a control system for an electronic circuit iteratively applies voltage to and senses current from a load to regulate operation of the load.
US08760074B2 Tunable white luminaire
A system provides white light having a selectable spectral characteristic (e.g. a selectable color temperature and intensity) using a combination of sources (e.g. LEDs) emitting light of four, five, or six different characteristics, for example, one or more white LEDs, and one or more LEDs of each of three primary colors plus cyan and royal blue. A microcontroller can maintain a desired spectral characteristic, e.g. for white light at a selected point on or within a desired range of the black body curve. Further, the microcontroller provides tunability of the spectral characteristic and intensity of the white luminaire. One channel driver drives the one or more first color LEDs (white in our example) as well as the one or more second color LEDs which are connected in series to the first channel driver. The other light sources are each driven by separate drivers on separate channels.
US08760069B2 Circuit arrangement and method for operating a high pressure discharge lamp
A method for operating a high pressure discharge lamp, with the high pressure discharge lamp being operated by a current inverter with a square wave lamp current having a positive phase with positive current flow and a negative phase with negative current flow, and with the current inverter being controlled by a control arrangement wherein the method comprises the steps of measuring a value for the positive current flow representing the lamp wattage or the square wave lamp current, measuring a value for the negative current flow representing the lamp wattage or the square wave lamp current; calculating a predetermined setpoint value in each case from a guide variable of a lamp wattage or of the square wave lamp current and the measured value for the phase with positive current flow; calculating a predetermined setpoint value in each case from a guide variable of a lamp wattage or of the square wave lamp current and the measured value for the phase with negative current flow; and outputting the two predetermined setpoint values to the current inverter.
US08760062B2 Circuit and method of driving light emitting diodes
An LED drive method is disclosed. In this way, the LED drive method allows not only the reference voltage to be periodically updated on the basis of the feedback drive voltages but also the drive voltage control signal to be generated using the updated reference voltage, in order to adjust the LED drive voltage applied to the LED array. Therefore, the LED drive circuit is hardly affected by the external environmental noise.
US08760059B2 Current-preheat electronic ballast and resonant capacitor adjusting circuit thereof
A current-preheat electronic ballast includes an AC-to-DC converter, a controlling unit, an auxiliary voltage generator, and an inverter. The inverter is connected with the DC bus for converting a high DC voltage into an AC output voltage and generating a resonant current and a lamp filament current to a lamp group. The inverter includes a resonant circuit and a resonant capacitor adjusting circuit. The resonant circuit provides electric energy required to preheat the lamp group. The resonant capacitor adjusting circuit judges whether the inverter is enabled according to the detecting element. After the inverter has been enabled for a delayed time, two high-voltage switching terminals of the resonant capacitor adjusting circuit are correspondingly conducted or shut off, so that an equivalent resonant capacitance value of the resonant circuit is changed and a voltage drop across two ends of a lamp filament of the lamp group is changed.
US08760052B2 Indicator lamp lighting circuit for vehicle
If a state to be informed occurs during an on-state of an ignition switch of a vehicle, a first and a second switching transistor are turned on by a control signal of a signal line, and an indicator lamp is lighted by power from a meter power supply. In addition, a third and a fourth switching transistor are turned on by a sub control signal of the signal line during an off-state of the ignition switch, and the indicator lamp is lighted by power from a continuous power supply.
US08760045B2 Spark plug for internal combustion engines and method for manufacturing the spark plug
A spark plug for internal-combustion engines equipped with a center electrode and a ground electrode is provided. In the spark plug, the ground electrode is fixed to a mount fitting, while the ground electrode has a convex portion. The convex portion is made of a part of base materials of the ground electrode where the part is facing the center electrode, and is projected toward the center electrode. The convex portion has a fusion solidification part made of precious metal materials and a part of the base materials melted together and solidified at least on part of an electric discharge surface facing the center electrode.
US08760044B2 Electrode material for a spark plug
An electrode material may be used in spark plugs and other ignition devices including industrial plugs, aviation igniters, glow plugs, or any other device that is used to ignite an air/fuel mixture in an engine. In one embodiment, the electrode material has one or both of iridium (Ir) or ruthenium (Ru), and has rhenium (Re).
US08760040B2 Polymer blend composition and tunable actuators using the same
The present invention relates to one of energy conversion devices, actuator and a dielectric layer used in the actuator. The present invention provides a polymer blend composition capable of easily controlling the ability of converting electrical energy to mechanical energy, which is prepared by blending a piezoelectric polymer with a flexible elastomeric block copolymer showing an effective miscibility therewith, and a tunable actuator using the same.
US08760039B2 Compact active vibration control system for a flexible panel
A diamond-shaped actuator for a flexible panel has an inter-digitated electrode (IDE) and a piezoelectric wafer portion positioned therebetween. The IDE and/or the wafer portion are diamond-shaped. Point sensors are positioned with respect to the actuator and measure vibration. The actuator generates and transmits a cancelling force to the panel in response to an output signal from a controller, which is calculated using a signal describing the vibration. A method for controlling vibration in a flexible panel includes connecting a diamond-shaped actuator to the flexible panel, and then connecting a point sensor to each actuator. Vibration is measured via the point sensor. The controller calculates a proportional output voltage signal from the measured vibration, and transmits the output signal to the actuator to substantially cancel the vibration in proximity to each actuator.
US08760032B2 Energy recovering device with a liquid electrode
An energy recovery device including: at least one capacitor with variable capacitance, the capacitor including a fixed electrode, a dielectric layer, and a liquid electrode; and a mechanism to inject an electric charge into the capacitor and to remove the electric charge therefrom, including a charge injection electrode forming a portion of the second face positioned upstream from the fixed electrode in the direction of displacement of the liquid electrode, and a charge removal electrode forming a portion of the second face positioned downstream from the fixed electrode in the direction of displacement of the liquid electrode.
US08760031B2 Electromechanical transducer and method for manufacturing the same which suppresses lowering of sensitivity while a protective layer is formed
An electromechanical transducer of the present invention includes a first electrode, a vibrating membrane formed above the first electrode through a gap, a second electrode formed on the vibrating membrane, and an insulating protective layer formed on a surface of the second electrode side. A region where the protective layer is not formed is present on at least part of a surface of the vibrating membrane.
US08760023B2 Transverse and/or commutated flux systems having phase offset
Electrical machines, for example transverse flux machines and/or commutated flux machines, may be configured to achieve reduced overall cogging torque via implementation of a sixth-phase offset. Individual cogging torque waveforms in the electrical machine may be evenly distributed across one-sixth of a voltage phase or other suitable spacing, resulting in a reduced magnitude and/or increased sinusoidality of the overall cogging torque waveform for the electrical machine.
US08760019B2 Rotating electric machine terminal arrangement
A rotating electric machine includes a rotor and a stator. The stator coil of the stator includes a set of a first stator coil and a second stator coil that is stored in an adjacent slot to a slot in which the first stator coil is stored, with a number of the set being same as a number of phases, and one end of each of the first stator coil and the second stator coil is a lead section and an other end is a neutral point. A plurality of the stator coils are arranged radially in layers in each slot, and a lead section of the first stator coil and a lead section of the second stator coil are connected with each other with one of the lead sections extending from an outermost layer of the slot and an other of the lead sections extending from an innermost layer of the slot so that the connected lead sections constitute an external connection terminal.
US08760011B2 Fan
A fan includes a housing, a cable, a number of blades received in and mounted to the housing, a motor driving the blades to operate and receiving electric energy by the cable, and a switch mounted on a bottom of the housing and connected with the cable. When the fan presses the switch, the cable and the switch form a closed circuit. When the fan releases pressure from the switch, the closed circuit is opened.
US08760009B2 Wireless power source
A wireless power transmission system includes a transmitting portion and a receiving portion. The transmitting portion includes an inductive coil as a transmitting antenna. The inductive coil will have 20-40 turns. A control circuit includes a field-effect transistor, a signal generator, and a capacitor with a resistor in parallel connection with the capacitor. The capacitor is typically a 1.5 microFarad Mylar® film capacitor. The resistor will be 2-4 ohms. The field-effect transistor may be a Metal Oxide Semiconductor Field Effect Transistor (MOSFET). The receiving unit has at least one loop stick antenna located at a distance from a center of the coil of up to twice a diameter of the coil. The circuit is tunable between 6 kHz and 10 kHz. 8 kHz has been found to be optimal. The inductive transmitting coil is closely coupled. The loop stick antennae of the receiving portion may have an iron core or a ferrite core.
US08760008B2 Wireless energy transfer over variable distances between resonators of substantially similar resonant frequencies
Described herein are embodiments of a first resonator, with a resonant frequency f1, optionally coupled to an energy source; and a second resonator, with a resonant frequency f2, optionally coupled to an energy drain, located a variable distance from the first resonator. The first resonator and the second resonator may be coupled to provide near-field wireless energy transfer among the first resonator and the second resonator, and where f1 may be approximately equal to f2 and both f1 and f2 may be less than 400 MHz.
US08760006B2 Wireless power transmission/reception apparatus and method having communication function
Disclosed herein is a wireless power transmission/reception apparatus and method having a communication function.The wireless power transmission/reception apparatus includes a wireless power transmission device and wireless power transmission devices. The wireless power transmission device receives a returned wireless power signal, detects the number of power consumption devices, modulates pieces of ID data, each including ID of a corresponding power consumption device, transmits the modulated ID data, receives returned ID data, and determines suitableness of the power consumption devices. Each of the wireless power reception devices returns a remaining wireless power signal which is not received among wireless power signals from the wireless power transmission device, and temporarily stops a power consumption device when an ID of the received ID data is an ID of a power consumption device connected thereto, thus returning ID data which will be subsequently received to the wireless power transmission device.
US08760004B2 Electrical power distribution
The present invention relates generally to electrical power distribution, for example, in aircraft. More particularly, according to a first aspect, the present invention relates to a power supply system for power distribution to one or more loads in a safety-critical power supply network. The power supply system comprises at least one power source, a power bus and a distributed control system. The distributed control system comprises a central controller operably coupled to at least one bus module through a data bus. Bus modules include bus controllers that are operable to connect respective power sources to the power bus.
US08760003B2 Vehicle-use power supply control apparatus and control apparatus for controlling electric rotating machine mounted on vehicle as main engine
The vehicle-use power supply control apparatus is for controlling transmission of electric power between a vehicle-mounted power supply apparatus including switching elements turned on and off in accordance with manipulation signals and an external power supply located outside the vehicle. The vehicle-use power supply control apparatus includes a control section to output an electric power transmission command signal depending on an electric power transmission request signal received from an external device, and a manipulation signal generating section to generate the manipulation signals based on the electric power transmission command signal received from the control section. The control section is configured to operate in order that noise sound generated due to switching operation of the vehicle-mounted power supply apparatus is within an audio frequency range.
US08760001B2 Supplying circuit for the electrical supply of a vehicle
A supply circuit is provided for the electrical supply of a vehicle. Here, a battery for generating a battery supply voltage and a step-up converter for generating an intermediate voltage from the battery supply voltage are provided. A temporary store is supplied from the intermediate voltage and serves for storing electrical energy. A step-down converter for generating a first consumer voltage for supplying a first consumer from the intermediate voltage and a second step-down converter for generating a second consumer voltage for supplying a second consumer from the intermediate voltage are provided. A control circuit serves to control the step-up converter, the first step-down converter and the second step-down converter.
US08759998B2 Energy recovery system and method for exhaust energy capture and electrical generation
An exhaust energy recovery and electrical generation system includes a conduit having a first end and a second end, wherein the first end of the conduit is configured to receive a gas flow transmitted by a gas flow channel of a gas flow source and wherein the conduit is configured to transmit the received gas flow from the first end thereof toward the second end thereof. A first blade assembly is coupled to the conduit, wherein the first blade assembly is configured to be moved when the received gas flow is transmitted from the first end of the conduit; and an electrical generator coupled to the first blade assembly to generate electricity when the first blade assembly moves. A cross-sectional area of the first end of the conduit may be less than a cross-sectional area of the gas flow channel.
US08759996B2 Method and apparatus for harnessing hydro-kinetic energy
Apparatus and method is disclosed for generating usable power derived from oscillatory hydro-kinetic energy available in the movement of waves having a given height and being spaced apart by a predetermined distance at the surface of a body of water. Apparatus and method is disclosed for generating usable power derived from hydro-kinetic energy available in a body of water moving in at least one direction of movement, the at least one direction being substantially horizontal or substantially vertical. Apparatus and method is disclosed for generating usable power derived from hydro-gravitational forces available at a site having a source of water at a first elevation higher than a second elevation at a selected location where the usable power is to be derived.
US08759994B2 Method of controlling a wind turbine generator and apparatus for controlling electric power generated by a wind turbine generator
A method of controlling a wind turbine generator is provided, the wind turbine generator converting mechanical energy to electrical. The method comprises: determining an electromagnetic power reference representing the electromagnetic power generated by the wind turbine generator, wherein the electromagnetic power reference is determined based on a desired output of the wind turbine generator; controlling the electrical power generated by the wind turbine generator using a control signal, wherein the control signal is derived from the electromagnetic power reference and is modified in dependence on an inverse power function of the wind turbine generator by incorporating minimal copper loss constraint and stator voltage limiting constraint such that non-linearity of the wind turbine generator plant is compensated in the control loop and it operates at its maximum efficiency. One effect of the method is that classical linear control loop design can be employed in spite of the plant being a non-linear identity.
US08759985B2 Methods for multi-wire routing and apparatus implementing same
A rectangular interlevel connector array (RICA) is defined in a semiconductor chip. To define the RICA, a virtual grid for interlevel connector placement is defined to include a first set of parallel virtual lines that extend across the layout in a first direction, and a second set of parallel virtual lines that extend across the layout in a second direction perpendicular to the first direction. A first plurality of interlevel connector structures are placed at respective gridpoints in the virtual grid to form a first RICA. The first plurality of interlevel connector structures of the first RICA are placed to collaboratively connect a first conductor channel in a first chip level with a second conductor channel in a second chip level. A second RICA can be interleaved with the first RICA to collaboratively connect third and fourth conductor channels that are respectively interleaved with the first and second conductor channels.
US08759983B2 Semiconductor device
A semiconductor device according to one embodiment includes: a semiconductor substrate provided with a semiconductor element; a connecting member formed above the semiconductor substrate configured to electrically connect upper and lower conductive members; a first insulating film formed in the same layer as the connecting member; a wiring formed on the connecting member, the wiring including a first region and a second region, the first region contacting with a portion of an upper surface of the connecting member, and the second region located on the first region and having a width greater than that of the first region; and a second insulating film formed on the first insulating film so as to contact with at least a portion of the first region of the wiring and with a bottom surface of the second region.
US08759980B2 Forming array contacts in semiconductor memories
Array contacts for semiconductor memories may be formed using a first set of parallel stripe masks and subsequently a second set of parallel stripe masks transverse to the first set. For example, one set of masks may be utilized to etch a dielectric layer, to form parallel spaced trenches. Then the trenches may be filled with a sacrificial material. That sacrificial material may then be masked transversely to its length and etched, for example. The resulting openings may be filled with a metal to form array contacts.
US08759973B2 Microelectronic assemblies having compliancy and methods therefor
A microelectronic assembly is disclosed that includes a semiconductor wafer with contacts, compliant bumps of dielectric material overlying the first surface of the semiconductor wafer, and a dielectric layer overlying the first surface of the semiconductor wafer and edges of the compliant bumps. The compliant bumps have planar top surfaces which are accessible through the dielectric layer. Conductive traces may be electrically connected with contacts and extend therefrom to overlie the planar top surfaces of the compliant bumps. Conductive elements may overlie the planar top surfaces in contact with the conductive traces.
US08759969B1 Integrated circuit dice with edge finishing
In various embodiments, an integrated circuit die is provided. The integrated circuit die may include a circuit on a surface of a semiconductor substrate that has a peripheral sidewall extending substantially perpendicular to and away from the surface. A first protective layer may cover the sidewall of the semiconductor substrate and peripheral edges of the circuit to provide protection from contaminant diffusion. In some embodiments, a semiconductor substrate is provided that has a plurality of dice contained thereon. Each of the dice may have an integrated circuit region and a peripheral sidewall etched into the semiconductor substrate. A first protective layer may be used to cover the peripheral sidewall of the semiconductor substrate to provide protection from contaminant diffusion. Additional apparatuses, systems, and methods are disclosed.
US08759958B2 Semiconductor package and method of manufacturing the same
A semiconductor package includes a first package and a second package, a connection terminal disposed between the first and second packages and including a first solder ball and a second solder ball that are vertically stacked, a solder passivation layer with which a surface of at least one of the first and second solder balls is coated, and a ring-shaped short prevention part surrounding a coupling portion between the first and second solder balls.
US08759957B2 Film for use in manufacturing semiconductor device, method for producing semiconductor device and semiconductor device
A film for use in manufacturing a semiconductor device having at least one semiconductor element of the present invention is characterized by comprising: a base sheet having one surface; and a bonding layer provided on the one surface of the base sheet, the bonding layer being adapted to be bonded to the semiconductor element in the semiconductor device, the bonding layer being formed of a resin composition comprising a crosslinkable resin and a compound having flux activity. Further, it is preferred that in the film of the present invention, the semiconductor element is of a flip-chip type and has a functional surface, and the bonding layer is adapted to be bonded to the functional surface of the semiconductor element.
US08759955B2 Semiconductor device with chips on isolated mount regions
Conventional semiconductor devices have a problem that it is difficult to prevent the short circuit between chips and to improve accuracy in temperature detection with the controlling semiconductor chips. In a semiconductor device of the present invention, a first mount region to which a driving semiconductor chip is fixedly attached and a second mount region to which a controlling semiconductor chip is fixedly attached are formed isolated from each other. A projecting area is formed in the first mount region, and the projecting area protrudes into the second mount region. The controlling semiconductor chip is fixedly attached to the top surfaces of the projecting area and the second mount region by use of an insulating adhesive sheet material. This structure prevents the short circuit between the two chips, and improves accuracy in temperature detection with the controlling semiconductor chip.
US08759954B2 Integrated circuit package system with offset stacked die
An integrated circuit package system provides a leadframe having a short lead finger and a long lead finger, and the long lead finger and the short lead finger reside substantially within the same horizontal plane. A first die is placed in the leadframe. A second die is offset from the first die. The offset second die is attached over the first die and the long lead finger with an adhesive. The first die is electrically connected to the short lead finger. The second die is electrically connected to at least the long lead finger or the short lead finger. At least portions of the leadframe, the first die, and the second die are encapsulated in an encapsulant.
US08759953B2 Electronic component including a shielding metal film disposed on a resin layer
In an electronic component, an active chip element and a passive chip element are respectively enclosed within first and second resin layers, which are separately disposed on upper and lower surfaces of a core substrate, respectively. The first resin layer includes a shielding metal film disposed on an upper surface thereof and a first via-hole conductor which connects the shielding metal film with a circuit pattern provided on the core substrate. The second resin layer includes an external-terminal electrode disposed on a lower surface thereof and a second via-hole conductor which connects the external-terminal electrode with a circuit pattern provided on the core substrate.
US08759948B2 Laser beam machining method and semiconductor chip
An object to be processed 1 comprising a substrate 4 and a plurality of functional devices 15 formed on a front face 3 of the substrate 4 is irradiated with laser light L while locating a converging point P within the substrate 4, so as to form at least one row of a divided modified region 72, at least one row of a quality modified region 71 positioned between the divided modified region 72 and the front face 3 of the substrate 4, and at least one row of an HC modified region 73 positioned between the divided modified region 72 and a rear face 21 of the substrate 4 for one line to cut 5. Here, in a direction along the line to cut, a forming density of the divided modified region 72 is made lower than that of the quality modified region 71 and that of the HC modified region 73.
US08759946B2 Semiconductor device
A semiconductor device which does not reduce writing property of a memory element and a method for manufacturing the same are proposed even in the case of forming a silicon film at a step portion formed by a surface of a substrate and a wiring formed over the substrate. The semiconductor device includes a plurality of the memory elements comprising a first electrode formed over a substrate having an insulating surface, sidewall insulating layer formed on side surface of the first electrode, a silicon film formed to cover the first electrode and the sidewall insulating layer, and a second electrode formed over the silicon film, and at least one of the first electrode and the second electrode is formed with a material being capable of being alloyed with the silicon film.
US08759945B2 Fuse structures, e-fuses comprising fuse structures, and semiconductor devices comprising e-fuses
A fuse structure, an e-fuse including the fuse structure and a semiconductor device including the e-fuse are disclosed. The fuse structure includes first and second electrodes extending in a first direction, and spaced a predetermined distance apart from each other and having one ends thereof facing each other, an insulation layer formed between the one end of the first electrode and the one end of the second electrode facing each other, and a conductive film overlapping portions of the first and second electrodes on the insulation layer and contacting the first electrode and the one end of the second electrode.
US08759942B2 Semiconductor device comprising an isolation trench including semiconductor islands
The present invention provides semiconductor devices and methods for fabricating the same, in which superior dielectric termination of drift regions is accomplished by a plurality of intersecting trenches with intermediate semiconductor islands. Thus, a deep trench arrangement can be achieved without being restricted by the overall width of the isolation structure.
US08759933B2 Solid-state image pickup element, method of manufacturing the same, and electronic apparatus using the same
Disclosed herein is a solid-state image pickup element, including: a semiconductor substrate; a pixel portion which is formed on the semiconductor substrate and in which a plurality of pixels each having a photoelectric conversion portion are arranged; an insulating layer formed on the semiconductor substrate so as to cover the photoelectric conversion portion; a hole portion formed in the insulating layer and above the photoelectric conversion portion; a silicon nitride layer formed so as to cover a bottom surface and a side surface of the hole portion; and a buried layer formed on the silicon nitride layer, wherein the silicon nitride layer is formed so as to contain a silicon nitride formed by utilizing an atomic layer deposition method.
US08759930B2 Low profile image sensor package
An image sensor package, and method of making same, that includes a printed circuit board having a first substrate with an aperture extending therethrough, one or more circuit layers, and a plurality of first contact pads electrically coupled to the one or more circuit layers. A sensor chip mounted to the printed circuit board and disposed at least partially in the aperture. The sensor chip includes a second substrate, a plurality of photo detectors formed on or in the second substrate, and a plurality of second contact pads formed at the surface of the second substrate which are electrically coupled to the photo detectors. Electrical connectors each electrically connect one of the first contact pads and one of the second contact pads. A lens module is mounted to the printed circuit board and has one or more lenses disposed for focusing light onto the photo detectors.
US08759926B2 Semiconductor physical quantity sensor
In a semiconductor physical quantity sensor, a pattern portion including a wiring pattern as a wiring is formed on a surface of a first semiconductor substrate. A support substrate having a surface made of an electrically insulating material is prepared. The first semiconductor substrate is joined to the support substrate by bonding the pattern portion to the surface of the support substrate. Further, a sensor structure is formed in the first semiconductor substrate. The sensor structure is electrically connected to the wiring pattern. A cap is bonded to the first semiconductor substrate such that the sensor structure is hermetically sealed.
US08759924B1 Monolithic integration of multiple compound semiconductor FET devices
Various aspects of the technology provide a dual semiconductor power and/or switching FET device to replace two or more discrete FET devices. Portions of the current may be distributed in parallel to sections of the source and drain fingers to maintain a low current density and reduce the size while increasing the overall current handling capabilities of the dual FET. Application of the gate signal to both ends of gate fingers, for example, using a serpentine arrangement of the gate fingers and gate pads, simplifies layout of the dual FET device. A single integral ohmic metal finger including both source functions and drain functions reduces conductors and contacts for connecting the two devices at a source-drain node. Heat developed in the source, drain, and gate fingers may be conducted through the vias to the electrodes and out of the device.
US08759921B2 Semiconductor memory device and method of manufacturing the same
A semiconductor memory device includes a plurality of memory blocks formed over a substrate including source regions and separated from each other by a slit, a plurality of bit lines coupled to the strings of the memory blocks and disposed over the memory blocks, and source contact lines formed within the slits, coupled to the source regions, respectively, and disposed in a direction to cross the plurality of bit lines.
US08759919B2 End-to-end gap fill using dielectric film
A method for fabricating a semiconductor device includes forming a plurality of gate structures on a semiconductor substrate. The plurality of gate structures are arranged in a plurality of lines, wherein an end-to-end spacing between the lines is smaller than a line-to-line spacing between the lines. The method further includes forming an etch stop layer over the gate structures, forming an interlayer dielectric over the gate structures, and forming a dielectric film over the gate structures before the interlayer dielectric is formed. The dielectric film merges in end-to-end gaps formed in the end-to-end spacing between the gate structures.
US08759912B2 High-voltage transistor device
A high-voltage transistor device comprises a spiral resistive field plate over a first well region between a drain region and a source region of the high-voltage transistor device, wherein the spiral resistive field plate is separated from the first well region by a first isolation layer, and is coupled between the drain region and the source region. The high-voltage transistor device further comprises a plurality of first field plates over the spiral resistive field plate with each first field plate covering one or more segments of the spiral resistive field plate, wherein the plurality of first field plates are isolated from the spiral resistive field plate by a first dielectric layer, and wherein the plurality of first field plates are isolated from each other, and a starting first field plate is connected to the source region.
US08759910B2 Trench MOSFET with trenched floating gates having thick trench bottom oxide as termination
A semiconductor power device with trenched floating gates having thick bottom oxide as termination is disclosed. The gate charge is reduced by forming a HDP oxide layer padded by a thermal oxide layer on trench bottom and a top surface of mesa areas between adjacent trenched gates. Therefore, only three masks are needed to achieve the device structure.
US08759909B2 Power MOSFET structure and method
A power MOSFET includes a semiconductor substrate with an upper surface, a cavity of a first depth in the substrate whose sidewall extends to the upper surface, a dielectric liner in the cavity, a gate conductor within the dielectric liner extending to or above the upper surface, body region(s) within the substrate of a second depth, separated from the gate conductor in a lower cavity region by first portion(s) of the dielectric liner of a first thickness, and source region(s) within the body region(s) extending to a third depth that is less than the second depth. The source region(s) are separated from the gate conductor by a second portion of the dielectric liner of a second thickness at least in part greater than the first thickness. The dielectric liner has a protrusion extending laterally into the gate conductor away from the body region(s) at or less than the third depth.
US08759906B2 Semiconductor device having vertical channel transistor and method for fabricating the same
A semiconductor device having a substrate; a plurality of pillar structures, wherein each pillar structure includes an active pillar disposed over the substrate; a gate electrode surrounding an outer wall of the active pillar; an interlayer dielectric (ILD) layer insulating adjacent pillar structures; a gate contact penetrating the ILD layer and configured to connect to a sidewall of the gate electrode; and a word line connected to the gate contact.
US08759904B2 Electronic device having plural FIN-FETs with different FIN heights and planar FETs on the same substrate
Electronic devices (20, 20′) of superior design flexibility that avoid channel-width quantization effects common with prior art fin-type (FIN) field effect transistors (FIN-FETS) (22) are obtained by providing multiple FIN-FETs (22) and at least one planar FET (32, 32′) on a common substrate (21), wherein the multiple FIN-FETs (22) have fins (231, 232) of at least fin heights H1 and H2, with H2
US08759900B2 Semiconductor memory devices
A semiconductor memory device includes a substrate including a cell region and a peripheral region, word lines on the substrate of the cell region, each of the word lines including a charge storing part and a control gate electrode sequentially stacked, and a peripheral gate pattern on the substrate of the peripheral region. Each of the control gate electrode and the peripheral gate pattern includes a high-carbon semiconductor pattern and a low-carbon semiconductor pattern, the low-carbon semiconductor pattern being on the high-carbon semiconductor pattern.
US08759899B1 Integration of 3D stacked IC device with peripheral circuits
An integrated circuit device includes a substrate including a first region and a second region. A pit is formed in the first region. A stack of active layers alternating with insulating layers is deposited in the pit. The stack includes a particular insulating layer. The particular insulating layer has a first thickness, where a sum of the first thickness, thickness of active layers, and thicknesses of other insulating layers is essentially equal to a depth of the pit. The first thickness is different than the thicknesses of the other insulating layers by an amount within a range of process variations for the depth of the pit, for the thicknesses of the active layers, and for the thicknesses of other insulating layers. The device includes a planarized surface over the first and second regions, where an uppermost one of the active layers has a top surface below the planarized surface.
US08759895B2 Semiconductor charge storage apparatus and methods
Methods of forming multi-tiered semiconductor devices are described, along with apparatus and systems that include them. In one such method, an opening is formed in a tier of semiconductor material and a tier of dielectric. A portion of the tier of semiconductor material exposed by the opening is processed so that the portion is doped differently than the remaining semiconductor material in the tier. At least substantially all of the remaining semiconductor material of the tier is removed, leaving the differently doped portion of the tier of semiconductor material as a charge storage structure. A tunneling dielectric is formed on a first surface of the charge storage structure and an intergate dielectric is formed on a second surface of the charge storage structure. Additional embodiments are also described.
US08759892B2 Semiconductor device including vertical transistor and method for manufacturing the same
A semiconductor device including a vertical transistor and a method for forming the same are disclosed, which can greatly reduce a cell area as compared to a conventional layout of 8F2 and 6F2, and need not form a bit line contact, a storage node contact, or a land plug, such that the number of fabrication steps is reduced and a contact region between the bit line and the active region is increased in size. The semiconductor device including a vertical transistor includes an active region formed over a semiconductor substrate, a first recess formed to have a predetermined depth at both sides of the active region, and a bit line buried in the first recess.
US08759888B2 Super trench schottky barrier schottky diode
A Schottky diode includes an n+-substrate, an n-epilayer, trenches introduced into the n-epilayer, floating Schottky contacts being located on their side walls and on the entire trench bottom, mesa regions between the adjacent trenches, a metal layer on its back face, this metal layer being used as a cathode electrode, and an anode electrode on the front face of the Schottky diode having two metal layers, the first metal layer of which forms a Schottky contact and the second metal layer of which is situated below the first metal layer and also forms a Schottky contact. Preferably, these two Schottky contacts have different barrier heights.
US08759883B2 Semiconductor integrated circuit
In a semiconductor integrated circuit device, a plurality of electrode pads for external connection are arranged in a zigzag pattern. Some electrode pads of the electrode pads of the plurality of I/O cells which are closer to a side of the semiconductor chip, each have an end portion closer to the side of the semiconductor chip, the end portion being set at the same position as that of an end portion of the corresponding I/O cell. A power source-side protective circuit and a ground-side protective circuit against discharge of static electricity are provided with the power source-side protective circuit being closer to the scribe region. A distance between a center position of one of the electrode pads and the ground-side protective circuit of the corresponding I/O cell and a distance between a center position of the other one electrode pad and the ground-side protective circuit of the corresponding I/O cell are both short and are substantially equal between each I/O cell.
US08759882B2 Semiconductor device with dynamic array sections defined and placed according to manufacturing assurance halos
An integrated circuit device includes a plurality of dynamic array sections, each of which includes three or more linear conductive segments formed within its gate electrode level in a parallel manner to extend lengthwise in a first direction. An adjoining pair of dynamic array sections are positioned to have co-located portions of outer peripheral boundary segments extending perpendicular to the first direction. Some of the three or more linear conductive segments within the gate electrode levels of the adjoining pair of dynamic array sections are co-aligned in the first direction and separated by an end-to-end spacing that spans the co-located portions of outer peripheral boundary segments of the adjoining pair of dynamic array sections. Each of these end-to-end spacings is sized to ensure that each gate electrode level manufacturing assurance halo portion of the first adjoining pair of dynamic array sections is devoid of the co-aligned linear conductive segments.
US08759879B1 RESURF III-nitride HEMTs
A semiconductor device containing a GaN FET has n-type doping in at least one III-N semiconductor layer of a low-defect layer and an electrical isolation layer below a barrier layer. A sheet charge carrier density of the n-type doping is 1 percent to 200 percent of a sheet charge carrier density of the two-dimensional electron gas.
US08759877B2 Stress release structures for metal electrodes of semiconductor devices
This invention teaches stress release metal electrodes for gate, drain and source in a field effect transistor and stress release metal electrodes for emitter, base and collector in a bipolar transistor. Due to the large difference in the thermal expansion coefficients between semiconductor materials and metal electrodes, significant strain and stresses can be induced in the devices during the fabrication and operation. The present invention provides metal electrode with stress release structures to reduce the strain and stresses in these devices.
US08759876B2 Enhancement-mode nitride transistor
A heterojunction for use in a transistor structure is provided. The heterojunction includes a barrier layer positioned beneath a gate region of the transistor structure. The barrier layer includes nitride-based semiconductor materials. A channel layer provides electrical conduction An intermediate layer near the barrier layer and including nitride-based semiconductor materials having a wider bandgap than the channel layer.
US08759868B2 Ultra-thin ohmic contacts for p-type nitride light emitting devices
A flip-chip semiconductor based Light Emitting Device (LED) can include an n-type semiconductor substrate and an n-type GaN epi-layer on the substrate. A p-type GaN epi-layer can be on the n-type GaN epi-layer and a metal ohmic contact p-electrode can be on the p-type GaN epi-layer, where the metal ohmic contact p-electrode can have an average thickness less than about 25 Å. A reflector can be on the metal ohmic contact p-electrode and a metal stack can be on the reflector. An n-electrode can be on the substrate opposite the n-type GaN epi-layer and a bonding pad can be on the n-electrode.
US08759867B2 Semiconductor light emitting device
A semiconductor light emitting device, has a package constituted by the lamination of a first insulating layer having a pair of positive and negative conductive wires formed on its upper face, an inner-layer wire below the first insulating layer, and a second insulating layer below the inner-layer wire; a semiconductor light emitting element that has a pair of positive and negative electrodes on the same face side and that is disposed with these electrodes opposite the conductive wires; and a sealing member that covers the semiconductor light emitting element, wherein part of the conductive wires is formed extending in the outer edge direction of the sealing member from directly beneath the semiconductor light emitting element, on the upper face of the first insulating layer, and is connected to the inner-layer wire via a conductive wire disposed in the thickness direction of the package, and the inner-layer wire is disposed so as to be spaced apart from the outer periphery of the semiconductor light emitting element in a see-through view of the package from the upper face side of the first insulating layer.
US08759866B2 Light emitting device
To provide a light emitting device that makes it possible to form a surface light emitting apparatus of less unevenness in luminance.The light emitting device 10 of the present invention comprises a light emitting element 30, connecting terminals 21a, 21b connected with the light emitting element 30, a package 12 which has a recess 40 wherein the light emitting element 30 is mounted and from which a part of each connecting terminal 21a, 21b is projected outward, an opening 41 of the recess 40 being elongated in one direction, wherein both side walls of the recess 40 positioned in the longitudinal direction of the recess 40 are inclined surface 43, an angle θ between both the inclined surfaces 43 being 90 degrees or more. In the light emitting device 10 of the present invention, light emitted by the light emitting element 30 is spread sufficiently in the longitudinal direction of the opening 41 so as to produce a band-shaped beam. As a result, when a plurality of light emitting devices 10 are disposed along the longitudinal direction of the light receiving surface 72 of the light guide plate 71 for constituting the surface light emitting apparatus 70, unevenness in luminance can be suppressed from occurring as dark portions are less likely to be generated between adjacent light emitting devices 10.
US08759864B2 Luminance-enhancing polarising plate for an organic light-emitting element
There is provided a polarizer for organic light emitting diodes (OLED) having improved brightness. The polarizer, which comprises a linear polarizer and a ¼ retardation plate, comprises a reflective polarizer film disposed between the linear polarizer and the ¼ retardation plate and transmitting a polarized light horizontal to the transmission axis of the linear polarizer while reflecting a polarized light vertical to the transmission axis of the linear polarizer. The polarizer may be useful to highly improve the brightness of the OLED device when the polarizer is used in the OLED device.
US08759861B2 LED device with cerium oxide dispersion layer and method for manufacturing same
An LED device includes: a substrate; an LED element provided on the substrate; a cerium oxide-dispersed composition layer containing a silicone resin and cerium oxide in an amount of 0.005 parts by weight or more and 0.03 parts by weight or less with respect to 100 parts by weight of the silicone resin, for covering the LED element; and a sealing material containing no cerium oxide for covering the cerium oxide-dispersed composition layer.
US08759860B2 Light emitting diode package and lens module used therein
An LED package includes an LED die and a lens module. The lens module covers the LED die. Light emitted from the LED die travels through the lens module. The lens module includes a concave lens and a convex lens with a smaller radial dimension than that of the concave lens. The concave lens covers the LED die. The convex lens is attached on a center of a surface of the concave lens away from the LED die. Optical axes of the concave lens and the convex lens are both collinear with a central axis of the LED die. Light from the LED die is diverged by the lens module to a peripheral side of the LED package.
US08759850B2 Quantum dot light enhancement substrate
A component including a substrate, at least one layer including a color conversion material including quantum dots disposed over the substrate, and a layer including a conductive material (e.g., indium-tin-oxide) disposed over the at least one layer. (Embodiments of such component are also referred to herein as a QD light-enhancement substrate (QD-LES).) In certain preferred embodiments, the substrate is transparent to light, for example, visible light, ultraviolet light, and/or infrared radiation. In certain embodiments, the substrate is flexible. In certain embodiments, the substrate includes an outcoupling element (e.g., a microlens array). A film including a color conversion material including quantum dots and a conductive material is also provided. In certain embodiments, a component includes a film described herein. Lighting devices are also provided. In certain embodiments, a lighting device includes a film described herein. In certain embodiments, a lighting device includes a component described herein.
US08759848B2 Light-emitting device
The application provides a light-emitting device, comprising a substrate; a plurality of first light-emitting diode units on the substrate, wherein every first light-emitting diode unit has a first electrode structure; and a plurality of second light-emitting diode units among the plurality of first light-emitting diode units, wherein every second light-emitting diode unit has a second electrode structure. The second electrode structure of the second light-emitting diode unit is flipped over and electrically connected with the adjacent first electrode structure of the first light-emitting diode unit.
US08759843B2 Optical/electrical transducer using semiconductor nanowire wicking structure in a thermal conductivity and phase transition heat transfer mechanism
An optical/electrical transducer device has housing, formed of a thermally conductive section and an optically transmissive member. The section and member are connected together to form a seal for a vapor tight chamber. Pressure within the chamber configures a working fluid to absorb heat during operation of the device, to vaporize at a relatively hot location as it absorbs heat, to transfer heat to and condense at a relatively cold location, and to return as a liquid to the relatively hot location. The transducer device also includes a wicking structure mounted within the chamber to facilitate flow of condensed liquid of the working fluid from the cold location to the hot location. At least a portion of the wicking structure comprises semiconductor nanowires, configured as part of an optical/electrical transducer within the chamber for emitting light through and/or driven by light received via the transmissive member.
US08759841B2 Light emitting device package and lighting system
A light emitting device package includes a sub mount; a light emitting device on the sub mount, and configured to generate light of a first wavelength; a dielectric layer disposed on the sub mount; and a fluorescent layer on the dielectric layer, and configured to convert the light of the first wavelength into light of a second wavelength, wherein the dielectric layer includes a plurality of layers having at least two different refractive indices, that transmits the light of the first wavelength and reflects the light of the second wavelength.
US08759834B2 Display panel
A display panel includes; a lower gate line, a lower data line disposed substantially perpendicular to the lower gate line, a thin film transistor (“TFT”) connected to the lower gate line and the lower data line, an insulating layer disposed on the lower gate line, the lower data line, and the TFT and having a plurality of trenches exposing the lower gate line and the lower data line, an upper gate line disposed in the trench on the lower gate line, an upper data line disposed in the trench on the lower data line, and a pixel electrode connected to the TFT.
US08759833B2 Thin film transistor array panel and method of manufacturing the same
A thin film transistor (“TFT”) array panel is provided. The TFT array panel includes an insulation substrate, a gate line formed on the insulation substrate and including a gate electrode, a data line insulated from and intersecting the gate line, and including a source electrode, a drain electrode opposite to the source electrode on the gate line, and a semiconductor formed in a layer between the data line and the gate line, and having a protruding portion extending below the drain electrode, wherein a portion of the semiconductor extending towards the drain electrode, from an area occupied by the data line, is positioned within an occupying area of the gate line including the gate electrode.
US08759831B2 Thin film transistor array structure and manufacturing method thereof
A thin film transistor (TFT) array structure for a liquid crystal display (LCD) includes a panel, a first conductive layer, a middle layer, a second conductive layer, a passivation layer, and a black electrode layer. The first conductive layer is formed on the panel using filming technologies and a first photo-mask process. The middle layer is deposited and formed on the first conductive layer using a second photo-mask process. The second conductive layer is formed on the middle layer using a third photo-mask process and a first etching operation. The passivation layer is deposited and formed on the middle layer and the second conductive layer using a forth photo-mask process and a second etching operation. The black electrode layer formed on the passivation layer. The TFT array structure and the manufacturing method of the present disclosure reduce the consumption of the voltage and improve the display effect of the LCD.
US08759825B2 Element substrate and light emitting device
A light emitting device and an element substrate which are capable of suppressing variations in the luminance intensity of a light emitting element among pixels due to characteristic variations of a driving transistor without suppressing off-current of a switching transistor low and increasing storage capacity of a capacitor. According to the invention, a depletion mode transistor is used as a driving transistor. The gate of the driving transistor is fixed in its potential or connected to the source or drain thereof to operate in a saturation region with a constant current flow. A current controlling transistor which operates in a linear region is connected in series to the driving transistor, and a video signal for transmitting a light emission or non-emission of a pixel is inputted to the gate of the current controlling transistor through a switching transistor.
US08759819B2 Organic electroluminescence device
An organic electroluminescence device includes an anode, a cathode, and an organic thin-film layer interposed between the anode and the cathode. The organic thin-film layer includes a phosphorescent-emitting layer containing a host and a phosphorescent dopant, and an electron transporting layer that is provided closer to the cathode than the phosphorescent-emitting layer. The host contains a substituted or unsubstituted polycyclic fused aromatic skeleton.
US08759816B2 Schottky-quantum dot photodetectors and photovoltaics
A composite material is described. The composite material comprises semiconductor nanocrystals, and organic molecules that passivate the surfaces of the semiconductor nanocrystals. One or more properties of the organic molecules facilitate the transfer of charge between the semiconductor nanocrystals. A semiconductor material is described that comprises p-type semiconductor material including semiconductor nanocrystals. At least one property of the semiconductor material results in a mobility of electrons in the semiconductor material being greater than or equal to a mobility of holes. A semiconductor material is described that comprises n-type semiconductor material including semiconductor nanocrystals. At least one property of the semiconductor material results in a mobility of holes in the semiconductor material being greater than or equal to a mobility of electrons.
US08759812B2 Semiconductor light emitting device and method for manufacturing same
According to an embodiment, a semiconductor light emitting device is configured to emit light by energy relaxation of an electron between subbands of a plurality of quantum wells. The device includes an active layer and at least a pair of cladding layers. The active layer is provided in a stripe shape extending in a direction parallel to an emission direction of the light, and includes the plurality of quantum wells; and the active layer emits the light with a wavelength of 10 μm or more. Each of the cladding layers is provided both on and under the active layer respectively and have a lower refractive index than the active layer. At least one portion of the cladding layers contains a material having a different lattice constant from the active layer and has a lower optical absorption at a wavelength of the light than the other portion.
US08759811B2 Particle encapsulated nanoswitch
The disclosed system, device and method for molecular-scale electronic switching generally includes a carbon nanotube, an anode, a cathode and two conductive particles encapsulated within the carbon nanotube, wherein the particles are configured to move between high resistance and low resistance states. Disclosed features and specifications may be variously controlled, adapted or otherwise optionally modified to realize improved switching function.
US08759807B2 Memory cells
Some embodiments include methods of forming memory cells. An opening is formed over a first conductive structure to expose an upper surface of the first conductive structure. The opening has a bottom level with a bottom width. The opening has a second level over the bottom level, with the second level having a second width which is greater than the bottom width. The bottom level of the opening is filled with a first portion of a multi-portion programmable material, and the second level is lined with the first portion. The lined second level is filled with a second portion of the multi-portion programmable material. A second conductive structure is formed over the second portion. Some embodiments include memory cells.
US08759802B2 Automated slice milling for viewing a feature
A method and apparatus for performing a slice and view technique with a dual beam system. The feature of interest in an image of a sample is located by machine vision, and the area to be milled and imaged in a subsequent slice and view iteration is determined through analysis of data gathered by the machine vision at least in part. A determined milling area may be represented as a bounding box around a feature, which dimensions can be changed in accordance with the analysis step. The FIB is then adjusted accordingly to slice and mill a new face in the subsequent slice and view iteration, and the SEM images the new face. Because the present invention accurately locates the feature and determines an appropriate size of area to mill and image, efficiency is increased by preventing the unnecessary milling of substrate that does not contain the feature of interest.
US08759801B2 Ion implantation apparatus and ion implantation method
During ion implantation into a wafer, an ion beam current is measured, a change in vacuum conductance which changes in accordance with a change of the location of a structure operating in a vacuum beam line chamber or a vacuum treatment chamber is obtained, furthermore, changes in degree of vacuum at one or plural places are detected using a vacuum gauge installed in the vacuum beam line chamber or the vacuum treatment chamber. The amount of an ion beam current is corrected using the obtained vacuum conductance and the detected degree of vacuum at one or plural places, and the dose amount implanted into the wafer is controlled.
US08759797B2 Drawing apparatus, drawing method, and method of manufacturing article
A drawing apparatus performs drawing overlaid with a shot formed on a substrate with a plurality of charged particle beams based on a plurality of drawing stripe data that constitute drawing data. The apparatus includes a charged particle optical system configured to generate the plurality of charged particle beams; and a controller configured to generate a plurality of intermediate stripe data as data of a plurality of intermediate stripes, adjacent ones of the plurality of intermediate stripes overlapping with each other, to obtain information on distortion of the shot, and to transform the plurality of intermediate stripe data based on the information on the distortion to generate the plurality of drawing stripe data.
US08759796B2 Particle beam system
A particle beam system includes a particle beam source for generating a particle beam, a high voltage source, a beam blanker system with deflection plates 56, 57, and a control circuit. The control circuit provides a first current path 67 between the two deflection plates, wherein a switch 70, a node 72 connected to the high voltage source and a switch 76 are arranged in this order in the first current path starting from the deflection plate 56. The control circuit provides a second current path 85 between the deflection plate 56 and the deflection plate 57, wherein in the second current path, starting from the deflection plate 56, a series connection 88 comprising a voltage source 91 a switch 90, a node 86 connected to the high voltage source and a series connection 92 comprising a voltage source 95 and a switch 94 are arranged in this order.
US08759793B2 Method for determining material parameters of a doped semiconductor substrate by measuring photoluminescent radiation
Method for determining material parameters of a doped semiconductor substrate, including: applying electromagnetic excitation radiation in order to produce luminescent radiation in the semiconductor substrate, the temporal profile of the excitation radiation intensity is periodically modulated, so that the rate of generation of charge carrier pairs in the substrate has a maximum and minimum during an excitation period, and at least the relative temporal profile of the rate of generation G(t) is determined by time-dependent measurement of the excitation radiation intensity, time-resolved measuring luminescent radiation intensity emanating from a measuring region, at least the relative temporal profile of the intensity of the luminescent radiation Φ(t) is measured during an excitation period, determining a material parameter of the semiconductor substrate based on G(t) and Φ(t). The effective lifetime of the substrate is determined from the time difference between the maximum of G(t) and a corresponding maximum of Φ(t).
US08759790B2 Fluorescence image producing method, fluorescence image producing apparatus, and fluorescence image producing program
Method and apparatus for producing an image associated with a biological sample is disclosed. A processor focuses on a portion of the biological sample based on fluorescence of a first fluorescent material and captures an image of the portion of the biological sample based on fluorescence of the first fluorescent material and the second fluorescent material.
US08759789B2 Body module for an optical measurement instrument
A body module of an optical measurement instrument includes: a reception device (201) for receiving samples, a first plate (202), a second plate (203) substantially parallel with the first plate and movably supported relative to the first plate in a direction perpendicular to the first and second plates, and walls extending from outer edges of the first plate to outer edges of the second plate. The reception device is located in a measurement chamber constituted by the walls and the first and second plates. At least the second plate includes a fastening interface provided with an aperture. The fastening interface is suitable for an optical module to be mounted to the second plate. The measuring chamber provides protection against undesired stray light from surroundings. The movability of the second plate allows adjustment of a distance between a sample and an optical module mounted to the second plate.
US08759784B2 Apparatus and method for detecting high-engery radiation
A high-energy radiation detector apparatus, comprising a high-energy radiation detector substrate and a plurality of charge collection electrodes operatively coupled to first and second opposing sides of the detector substrate is disclosed. Charge collection circuitry is associated with the plurality of charge collection electrodes for collecting charge induced on the charge collection electrodes by a high energy radiation photon interaction event caused by high-energy radiation incident on the detector substrate.
US08759781B2 Radiation imaging system
Disclosed is a radiation imaging system comprising a layer for a radiation converter; a top electrode on the layer for a radiation converter; and an array of pixel unit electrically coupled to the layer for a radiation converter; wherein, said layer for a radiation converter comprises an organic matrix comprising a charge transport material (CTM); and scintillating particles for absorbing radiation, being dispersed in the organic matrix, wherein the scintillating particles are in contact with a charge generation material (CGM).
US08759770B1 System and method for qualifying usability risk associated with subsurface defects in a multilayer coating
A system for qualifying usability risk associated with subsurface defects in a multilayer coating includes a component having a multilayer coating, an infrared detection device for capturing infrared images of the multilayered coating and a processing unit that is in electronic communication with the infrared detection device where the processing unit generates a subsurface defect map of the multilayer coating based on the infrared images. The system further includes a risk map of the component.
US08759769B2 Terahertz-wave device, method of generating and detecting terahertz-waves with the device, and imaging apparatus equipped with the device
A terahertz-wave generating device including an optical waveguide containing an electrooptic crystal includes: first and second optical waveguides through which first and second light beams respectively propagate; a propagation portion through which a first terahertz wave propagates, the first terahertz wave being generated from the second optical waveguide in a direction different from a direction of the second light beam; and a delay portion arranged at incidence sides of the first and second light beams and configured to delay the first light beam relative to the second light beam. The first optical waveguide and the second optical waveguide are arranged with the propagation portion interposed therebetween. A first equiphase surface of the first terahertz wave is substantially aligned with a second equiphase surface of a second terahertz wave generated from the first optical waveguide in a direction different from a direction of the first light beam.
US08759768B2 Device for measuring physical quantities of nuclear materials and method of employing such a device
A movable device for measuring physical quantities of nuclear materials contained in a shielded cell, which device can be brought up against the shielded cell and can be retracted therefrom, the device configured to carry out the measurement in the position in which it is against the shielded cell. The device includes a carriage, a support member placed on the carriage, and a shielded container placed on the support member. The shielded container includes a transfer container configured to store the nuclear material to be measured, and an opening configured to be aligned with an opening in one wall of the shielded cell. The support member is made of graphite and includes a housing accommodating a neutron emission module, a casing covering the shielded container, the casing being made of graphite, and a neutron measurement mechanism fastened to the casing.
US08759766B2 Air supply tube, air supply device, and image forming apparatus
Provided is an air supply tube including an inlet port that takes in air, an outlet port that is arranged opposite a portion of an elongated target structure in a longitudinal direction, to which air taken in from the inlet port is to be supplied, and has an elongated opening shape, a channel portion in which a channel space for allowing air to flow between the inlet port and the outlet port is formed, and plural suppressing portions that suppress the flow of air, wherein the plural suppressing portions include at least a most downstream suppressing portion, a first upstream suppressing portion that is provided in a part initially located on the upstream side in the air flow direction, and a gap regulating portion that forms an extended gap at the same interval.
US08759764B2 On-axis detector for charged particle beam system
A split grid multi-channel secondary particle detector for a charged particle beam system includes a first grid segment and a second grid segment, each having independent bias voltages creating an electric field such that the on-axis secondary particles that are emitted from the target are directed to one of the grids. The bias voltages of the grids can be changed or reversed so that each grid can be used to detect the secondary particles and the multi-channel particle detector as a whole can extend its lifetime.
US08759763B2 Method and apparatus to measure step height of device using scanning electron microscope
A method of measuring a step height of a device using a scanning electron microscope (SEM), the method may include providing a device which comprises a first region and a second region, wherein a step is formed between the first region and the second region, obtaining a SEM image of the device by photographing the device using a SEM, wherein the SEM image comprises a first SEM image region for the first region and a second SEM image region for the second region, converting the SEM image into a gray-level histogram and calculating a first peak value related to the first SEM image region and a second peak value related to the second SEM image region, wherein the first peak value and the second peak value are repeatedly calculated by varying a focal length of the SEM, and determining a height of the step by analyzing a trend of changes in the first peak value according to changes in the focal length and a trend of changes in the second peak value according to the changes in the focal length.
US08759761B2 Charged corpuscular particle beam irradiating method, and charged corpuscular particle beam apparatus
According to a charged corpuscular particle beam irradiating method of this invention, a focusing element (19) which focuses the trajectories of charged corpuscular particles (12) emitted from a specimen (10) is arranged at a position which prevents focusing action by the focusing element (19) from affecting a charged corpuscular particle beam (4) traveling toward the specimen or can curb effects of the focusing action on the charged corpuscular particle beam (4). With this configuration, the focusing action selectively affects the charged corpuscular particles (12) emitted from the specimen (10), and effects of the focusing action on the charged corpuscular particle beam (4) traveling toward the specimen (10) are curbed. Thus, charged corpuscular particles emitted from the specimen (10) and traveling in a direction other than a direction toward a detector and the like can be focused and guided into the detector and the like, and a charged corpuscular particle beam irradiating method capable of efficiently detecting a charged corpuscular particle traveling in a direction other than the direction toward the detector and the like can be provided.
US08759759B2 Linear ion trap analyzer
The present invention relates generally to the field of ion storage and analysis, in particular to a linear ion trap mass analyzer comprised by multiple columnar electrodes. High frequency voltages are applied on at least one of the columnar electrodes to form ion confining space, which mainly consists of two-dimensional quadrupole electric radial trapping field, and there is at least one through slot for ion ejection in at least one direction perpendicular to the axis of the ion trap, wherein an AC electric field superposition is applied to invoke dipole excitation. Opposite to the through slot, there is an elongated electrode for field adjusting between two columnar electrodes or inside the slit of one of the columnar electrodes mentioned above. The potential on the elongated electrode for field adjusting is set as the sum of a portion of the high frequency voltage which applied on one adjacent columnar electrode and a DC offset, which can be adjusted freely. Through adjusting the portion of the high frequency potential and DC potential on this electrode, one or more objectives, including field optimization inside the ion trap as well as ion motion characteristics of resonant ejection, can be realized.
US08759752B2 Corrected mass analyte values in a mass spectrum
A method for determining a mass-to-charge ratio of an analyte is described that accounts for space charge limitations when there are relatively high concentrations of ions in an ion trap. The method includes calibrating a mass spectrometer for the space charge effects caused by the analyte ion itself and also for adjacent ions that have a mass-to-charge ratio different than the analyte ion. A mass spectrum can be measured for both an analyte ion and an adjacent ion where there is a relatively high concentration of ions in the ion trap. A corrected mass-to-charge ratio can be calculated for an analyte ion based on the measured analyte mass-to-charge ratio, the measured analyte abundance, the first mass-to-charge ratio difference, and the measured first adjacent ion abundance. The resulting corrected mass-to-charge ratio has an increased accuracy and at the same time improves the dynamic range of the ion trap mass analyzer.
US08759744B2 Apparatus and method for operating a spectrometer
A method of operating a spectrometer to determine the wavelength of an optical signal, in particular for determining the resonant wavelength of an optical fiber Bragg grating. The spectrometer comprises an array of photosensitive pixels each of which generates an output signal in response to the intensity of light incident on the pixel, and a refractive element arranged to direct light to a particular position in the array depending on the wavelength of the light. The method involves selecting a first group of pixels in the array by reference to an expected wavelength distribution of the optical signal and monitoring the output signals from the first group of pixels. On the basis of the output signals from the first group of pixels a second group of pixels is selected and the wavelength of the optical signal is determined from the output signals of the second group of pixels. The method has the advantage that the wavelength of the optical signal can be determined without scanning every pixel in the array individually.
US08759741B2 Titanium black dispersion, photosensitive resin composition, wafer level lens, light blocking film, method for producing the light blocking film, and solid-state image pickup element
A titanium black dispersion includes titanium black particles, a dispersant, and an organic solvent. When the titanium black dispersion is for a wafer level lens, 90% or more of dispersed objects that consist of the titanium black particles have particle diameters of 30 nm or less, or dispersed objects including the titanium black particles contains Si atoms and the content ratio of Si atoms to Ti atoms (Si/Ti) in the dispersed objects is 0.05 or higher. When the titanium black dispersion is used for formation of a light-shielding film that is provided on one side of a silicon substrate having an image pickup device section on the other side, and that shields against infrared light, 90% or more of dispersed objects that consist of the titanium black particles have particle diameters of 30 nm or less.
US08759736B2 Column circuit and pixel binning circuit for image sensor
A column circuit for an image sensor includes a first column read circuit configured to read data of a first column line, and a second column read circuit configured to read data of a second column line, wherein, during a binning mode, data from two or more pixels are outputted through the first column line and stored in the first column read circuit in a first phase, data from two or more pixels are outputted through the second column line and stored in the second column read circuit in a second phase, and charges are shared between the first column read circuit and the second column read circuit in a third phase.
US08759735B2 Multi-function airborne sensor system
Various embodiments provide a sensor system including a first optical sub-system having a first plurality of optical elements, and a second optical sub-system having a second plurality of optical elements including a first mirror. The second optical sub-system is configured to rotate about a first axis relative to the first optical sub-system and the first mirror is configured to rotate about a second axis substantially perpendicular to the first axis. The first axis and the second axis are arranged so as not to intersect each other so as to maximize a field of regard of the sensor system.
US08759734B2 Directional sensors for auto-commissioning lighting systems
Systems and methods for spatial commissioning of a lighting system are provided. A determination of which sensors receive a light signal from one or more emitter devices may be made. Each one of the sensors and/or each one of the emitter devices may provide a direction of the light signal detected by a respective one of the sensors. The direction of the light signal detected by the respective one of the sensors may be detected. A sensor graph based on the direction of the light signal may be generated, where nodes of the sensor graph represent the sensors and/or the emitter devices. Each one of the sensors and/or the emitter devices may be mapped to a corresponding location in a site model based on the sensor graph and on the site model, where locations of the sensors and/or the emitter devices are indicated by the site model.
US08759728B2 Apparatus for cooking food products on both sides thereof
An apparatus for cooking food products on both sides which has a food-support surface that is transparent to both microwave and infrared radiation, an electric heating device, and a microwave generator. The microwave generator is connected to a waveguide cavity for irradiating the food products. The apparatus also has a food-contact heating surface that, together with the food-support surface, forms a cooking chamber capable of retaining the microwaves inside. The electric heating device has a shielded resistor with the external shield electrically connected to ground. The apparatus has a partition element made of thermal-insulating and microwave-transparent material, a portion of which is below the shielded resistor to separate the resistor from the microwave generator. The waveguide cavity has a microwave launch aperture underneath the partition element. The microwaves exit the cavity and pass through the partition element, the shielded resistor, and the food-support surface and radiate into the cooking chamber.
US08759726B2 Dynamic power splitter
There is described a power splitter for directing electromagnetic power comprising: an input port for receiving the electromagnetic power; at least one dielectric element placed inside the power splitter; at least two output ports for outputting the power according to a splitting ratio, the at least two output ports placed on a surface opposite to the input port; and at least one dielectric moving device for positioning the at least one dielectric element between the at least two output ports to dynamically direct the power into the at least two output ports according to the power splitting ratio.
US08759723B2 System and method for low voltage detection for heat pump water heaters
Systems and methods for low voltage detection for a heat pump water heater are disclosed. A current sensor can be used to monitor current supplied to a inductive load, such as a compressor or evaporator fan, of the heat pump water heater. The current sensor can be coupled to a controller which receives and processes information from the current sensor to determine whether a low voltage condition of the heat pump water heater has occurred. An alert can be provided to an installer/user of the heat pump water heater that a low voltage condition has occurred. The controller can also disconnect the heat pump water heater from the power source to prevent damage to the heat pump water heater.
US08759722B2 Baby feeding apparatus
A baby feeding apparatus for the preparation and warming of infant formula with audio instructions includes a baby bottle having a well and an electrical probe for insertion into the well for heating the contents of the bottle. The apparatus also includes a reservoir for containing a supply of heated fluids such as water for maintaining the temperature of the infant formula and a visual and audio indicator to advise an individual when the temperature of the formula is appropriate for feeding a child. A brush for cleaning the bottle and a cover for the apparatus are also provided.
US08759720B2 Tortilla warmer control system for controlling the preparation and dispensing of tortillas
A tortilla warmer control system is disclosed for controlling preparation and dispensing of tortillas. The control system includes a control unit capable of receiving inputs from a user, and providing outputs. The control unit receives user inputs including: a frequency of heating sessions, a number of tortillas to be heated and dispensed during each heating session; and tortilla texture. The control unit provides outputs including: a speed at which tortillas are to be conveyed through a heating sub-system of the tortilla warmer, and/or a temperature to be provided during each heating session; and a heating session initiation signal. The user inputs received by the control unit can also include a selected rate at which the tortillas are to be dispensed during the heating session. The outputs provided by the control unit can also include a rate at which tortillas are introduced into the heating sub-system.
US08759716B2 Method and apparatus for welding with limited term software
A method and apparatus for welding uses a power circuit and a controller connected to the power circuit. The controller included a welding program having a limited term. The program may be part of a system, or a stand alone program. The controller has a data port and the welding program and/or an authorization is received by the controller on the data port in one embodiment. The welding program includes a limited time module, a limited time in use module, a limited arc start module, a controlled short circuit program, and/or a pulse program in various embodiments. A second welding program, without a limited term module, may be provided.
US08759710B2 Process and device for form locked joining of two components
A process is described for form locking joining of two components through plastic deformation of one of the two components. In order for the tool for forming the form locking connection not to get in direct contact with the plasticized area of the joining partners, a third component between the tool and the two components to be joined through form locking is being used, which simultaneously enters into an adhesive bond with one of the two components to be joined through form locking. The thermal energy for creating the plastic state of one of the joining partners and for developing the adhesive bond is applied through electromagnetic radiation through the third component.
US08759701B2 Switch apparatus
A switch apparatus adapted to be assembled with a casing of an electronic product, the switch apparatus includes a control device having a base portion, a position portion, at least a pressing portion, and a linking portion having one end connected to the casing. A resilient element is installed in the control device, and has a fixing portion fixed into the position portion, and at least a deforming portion and a contact portion. At least a triggering device is electrically connected with the printed circuit board. When the control device is being pressed with a first force, the triggering device is being pushed downwards by the contact portion, while the control device is being pressed with a second force larger than the first force, the at least a deforming portion deforms, and the contact portion continuing pressing against the triggering device.
US08759698B2 Key switch structure
There is provided a key switch structure including: a plate shaped key top; a link mechanism supporting the key top such that the key top can be depressed; a membrane sheet comprising a contact point portion; a back plate supporting the link mechanism and adhered to the membrane sheet; a plurality of holder members insert molded onto the back plate and supporting the link mechanism; and a resilient member provided between the key top and the membrane sheet, the resilient member being compressed by depressing of the key top and pressing the contact point portion to make a continuity.
US08759697B2 Molded case circuit breaker capable of withstanding short circuit conditions
A molded case circuit breaker includes a molded case containing a circuit breaker trip unit, and multiple line connector lugs attached to an end portion of the molded case for connecting the trip unit to power cables from a power source. Rigid support brackets attached to a rigid supporting surface extend along a pair of opposite outer side walls of the molded case adjacent the lugs to resist outward movement of the side walls in the event of a short circuit condition that exerts distorting forces on the lugs and the portions of the molded case adjacent the lugs. The rigid support brackets may be attached to a supporting pan attached to the portion of the molded case adjacent the lugs.
US08759696B2 Trigger switch for power tool
A trigger switch includes a case having a switching mechanism inside thereof and open on one side, a cover configured to be fitted inside an opening of the case to close the opening, and a trigger arranged outside of the case and configured to operate the switching mechanism by sliding operation via the plunger. An engaging depression is formed on an inner wall surface defining an opening edge portion of the case. A shoulder is formed on an outer peripheral end edge portion of the cover. An engaging projection is formed to project outward from a side surface of the shoulder to a small extent so as to be capable of engaging with the engaging depression corresponding thereto. A joint groove is formed by the inner wall surface of the opening edge portion of the case and the shoulder, and the joint groove is filled with an adhesive agent.
US08759695B2 Compact three-hole lug
A circuit breaker assembly includes a lug assembly with a main structural body having cable holes extending through a cable-receiving face, the cable holes including a first cable hole separated by a second cable hole from a third cable hole. Each of the cable holes is configured to receive a respective power cable. The structural body further includes wire-binding holes extending at least in part through a wire-binding face, the wire-binding holes including a first wire-binding hole separated by a second wire-binding hole from a third wire-binding hole. The first wire-binding hole has a first longitudinal axis at an angle that intersects a third longitudinal axis of the third wire-binding hole. A fastener is inserted through the second wire-binding hole, the fastener having an hourglass section with a contour that generally matches at least in part a corresponding contour of the first cable hole and the third cable hole.
US08759686B2 Printed circuit board providing heat dissipation
A printed circuit board includes an insulated base sheet, a heat-conducting layer, an insulated layer, a plurality of heat-conducting blocks, and a plurality of bonding pads. The heat-conducting layer is disposed on the insulated base sheet. The insulated layer is partially coated on the heat-conducting layer, leaving a plurality of exposed zones remaining thereon. The heat-conducting blocks are correspondingly formed on the exposed zones. The bonding pads are positioned on the heat-conducting layer for soldering circuit elements.
US08759682B2 Device for holding at least one longitudinal element, of the wiring harness or tube type, on a support
This device for holding at least one longitudinal element, of the wiring harness or tube type, on a support, comprises a deformable clamp that allows said longitudinal element to be inserted into the clamp and holds the longitudinal element, and a protective layer that at least partially covers the clamp. The clamp is made of thermoplastic, the protective layer being overmolded onto the clamp.
US08759678B2 Cable storage device and associated methods
Exemplary embodiments are directed to cable storage devices and associated methods. The exemplary cable storage device includes at least one chamber and at least one chamber path. The at least one chamber path detachably secures at least one cable in the at least one chamber path. The at least one chamber is configured and dimensioned to have at least one of a spring-like property or a flexible property. An alternative exemplary cable storage device includes at least one chamber and at least one coupling member. The coupling member detachably secures at least one cable in the at least one chamber path and further includes a first coupler and a second coupler having at least one of a spring-like property or a flexible property. In alternative exemplary embodiments, methods of cable storage are provided.
US08759676B1 Electrical box assembly for concrete poured floors
An electrical box assembly for concrete poured floors. The electrical box assembly includes a concrete can with an open end and a plurality of hubs with integral sockets for connection of electrical conduit thereto. Plugs are provided for closing off unused sockets. The electrical box assembly includes a mounting bracket for installation on the open end of the can, a duplex receptacle, a back plate and a cover plate. The back plate provides a seal between the mounting bracket and the cover plate. Removable threaded blanks are included for sealing the openings in the cover plate in order to gain access to the plug-ins on the duplex receptacle.
US08759675B2 Dual purpose casing
Disclosed is a casing for an electronic wireless handheld device defined by a front panel, a rear panel, and a plurality of side panels connecting the front and rear panels wherein, the device is to be received within the casing such that the front and rear exterior surfaces of the device abut the interior surfaces of the front and rear panels respectively. The casing comprises at least one receptacle wherein, each of the at least one receptacle is adapted to receive therewithin at least one accessory of the device and the like.
US08759674B2 Electrical box with multi-directional partition plate
An electrical box assembly includes an electrical box, a movable partition plate, and a cover having an opening for receiving and supporting an electrical wiring device such as a switch or duplex receptacle. The electrical box has a rear wall with a centrally located emboss having a plurality of screw holes for receiving a ground screw and ground wire. The partition plate has a recess for mating with the emboss and a top end for coupling with the cover member. The partition plate and cover member are adapted for coupling to the electrical box in different orientations so that the partition plate divides the electrical box into substantially equal size compartments for receiving high voltage and low voltage requirements.
US08759667B2 Photoelectric conversion device
Disclosed is a photoelectric conversion device with improved photoelectric conversion efficiency. In the disclosed photoelectric conversion device, an amorphous silicon photoelectric conversion unit with an amorphous i-type layer and a microcrystalline silicon photoelectric conversion unit with a microcrystalline i-type layer are laminated, and an intermediate layer, which is disposed between the amorphous silicon photoelectric conversion unit and the microcrystalline silicon photoelectric conversion unit, has a lower refractive index than the layers in contact with the front or back surfaces thereof, wherein the higher the crystalline fraction of the microcrystalline i-type layer in the panel surface, the thicker the film of the intermediate layer.
US08759664B2 Thin film solar cell strings
Thin film PV cells and strings of such cells that may be electrically joined with electrical conductors or electroconductive patterns are disclosed. The electrical conductors wrap or fold around the PV cells to form an electrical series connection among those cells. The electrical conductors may be formed or deposited on an electrically insulating sheet, which is then wrapped or folded around those cells. By constructing the electrical conductor and positioning the cells appropriately, an electrical connection is formed between one polarity of a given cell and the opposite polarity of the adjacent cell when the sheet is folded over. One or more dielectric materials may be applied or attached to exposed edges of the cells or conductive traces prior to folding the electrical conductors and/or electrically insulating sheet to prevent shorts or failure points.
US08759663B2 Method of manufacturing solar battery
An object is to provide a method of manufacturing a solar battery, in which residues such as a flux and organic matters remaining on cell surfaces are preferably removed and in which an energy conversion efficiency is largely enhanced, and the method comprises: a flux applying step of applying a flux to the surfaces of cells; a tab disposing step of disposing the tabs over the adjacent cells to which the flux has been applied; a tab string step of connecting the tabs to the cells by soldering; and a cell heating step of heating the cells connected to the tabs.
US08759660B2 Electronic musical instrument
Provided are an electronic musical instrument, computer storage device, and method generating tones for held notes. Indication is made of held notes having pitches as held in response to receiving note-on information for the held notes from an input device of an electronic musical instrument while receiving hold information from a hold device of the electronic musical instrument. Note-on information is received for a received note having a pitch while generating the pitches for the held notes. Selection is made of one of the held notes to release according to a first selection criteria in response to determining that the pitch difference of the received note and at least one of the held notes does not exceed the predetermined number of tones or selection is made according to a second selection criteria if the pitch difference exceeds the predetermined number of tones.
US08759657B2 Systems and methods for providing variable root note support in an audio player
A method for providing variable root note support in an audio player is described. A file with Musical Instrument Digital Interface (MIDI) data and a set of user defined instruments is received. A metric is determined using a user defined root note in the user defined instruments, a key number for a MIDI note in the MIDI data, and a player specific root note. The key number is adjusted based on the metric.
US08759655B2 Drum and drum-set tuner
Provided are systems and methods for resonance tuning. A signal is received in response to a resonance of a structure. A frequency or musical note related to an overtone is determined from the signal. The frequency or musical note related to the overtone is selected as a filter mode reference frequency or musical note. A display of frequencies or musical notes from a subsequent signal that deviate from the filter mode reference frequency or musical note by a predetermined threshold is suppressed.
US08759651B2 Tensioning apparatus and method for a stringed instrument
The present invention provides a tensioning apparatus for a string of a stringed instrument, the apparatus including a supporting body portion for releasable engagement between a string and a surface of the neck of the stringed instrument at a fret on the fret board, thereby to raise the string relative to the fret on the fret board; the apparatus further including a biasing element by which lateral tension may be applied to the string.
US08759649B2 Tubular metal neck for stringed musical instruments
This invention pertains to the neck for a stringed electronic musical instrument that is constructed of a pipe made of a steel alloy. The instrument has superior sound qualities, has optimal ergonomic properties that fit the natural grip of the human hand, maintains tune under conditions of environmental extremes and mechanical stress, and can be easily manufactured with a high degree of precision and accuracy on a mass scale.
US08759647B2 Sound boards for harps
Sound boards having an elongate, approximately trapezoid shape, provided on the front face with a central longitudinal profiled string-carrier member and on the reverse side with a central profiled reinforcing member or beam, and with two side profiled members or sound bars, symmetrically disposed with respect to the reinforcing beam are provided. In such sound boards the cross-section of the reinforcing beam has a central portion with an increased height or thickness and two adjacent, symmetrical side portions or wings having a height or thickness which tapers gradually towards the outside through a concave arcuate profile up to a predetermined minimum value.
US08759645B2 Wheat starch and wheat flours and foodstuffs containing these wheat starch/wheat flours
The present invention relates to wheat flours, the starch component whereof has an amylose content between 15.0 wt. % and 30.0 wt. % and which have a content of resistant starch of more than 5.0 wt. % and foodstuffs containing these wheat flours. Further, the present invention relates to methods for the production of said wheat flours and the use thereof as resistant starch, as a prebiotic or for the production of foodstuffs with decreased glycemic index. The present invention also relates to nucleic acid molecules which code for a soluble starch synthase II, and vectors containing such nucleic acid molecules. Further, the present invention also relates to host cells and plants which contain such nucleic acid molecules or vectors.
US08759644B1 Inbred corn line SSH65
An inbred corn line, designated SSH65, the plants and seeds of the inbred corn line SSH65, methods for producing a corn plant, either inbred or hybrid, produced by crossing the inbred corn line SSH65 with itself or with another corn plant, and hybrid corn seeds and plants produced by crossing the inbred line SSH65 with another corn line or plant and to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic corn plants produced by that method. This invention also relates to inbred corn lines derived from inbred corn line SSH65, to methods for producing other inbred corn lines derived from inbred corn line SSH65 and to the inbred corn lines derived by the use of those methods.
US08759643B1 Inbred corn line XHE06
An inbred corn line, designated XHE06, the plants and seeds of the inbred corn line XHE06, methods for producing a corn plant, either inbred or hybrid, produced by crossing the inbred corn line XHE06 with itself or with another corn plant, and hybrid corn seeds and plants produced by crossing the inbred line XHE06 with another corn line or plant and to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic corn plants produced by that method. This invention also relates to inbred corn lines derived from inbred corn line XHE06, to methods for producing other inbred corn lines derived from inbred corn line XHE06 and to the inbred corn lines derived by the use of those methods.
US08759641B1 Inbred corn line D065125
An inbred corn line, designated D065125, the plants and seeds of the inbred corn line D065125, methods for producing a corn plant, either inbred or hybrid, produced by crossing the inbred corn line D065125 with itself or with another corn plant, and hybrid corn seeds and plants produced by crossing the inbred line D065125 with another corn line or plant and to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic corn plants produced by that method. This invention also relates to inbred corn lines derived from inbred corn line D065125, to methods for producing other inbred corn lines derived from inbred corn line D065125 and to the inbred corn lines derived by the use of those methods.
US08759639B1 Maize variety hybrid X18C331
A novel maize variety designated X18C331 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X18C331 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X18C331 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X18C331, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X18C331. This invention further relates to methods for producing maize varieties derived from maize variety X18C331.
US08759636B1 Maize inbred PH1D84
A novel maize variety designated PH1D84 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1D84 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1D84 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1D84 or a locus conversion of PH1D84 with another maize variety.
US08759630B2 Soybean cultivar S110125
A soybean cultivar designated S110125 is disclosed. The invention relates to the seeds of soybean cultivar S110125, to the plants of soybean cultivar S110125, to the plant parts of soybean cultivar S110125, and to methods for producing progeny of soybean cultivar S110125. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S110125. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S110125, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S110125 with another soybean cultivar.
US08759629B2 Soybean cultivar S110124
A soybean cultivar designated S110124 is disclosed. The invention relates to the seeds of soybean cultivar S110124, to the plants of soybean cultivar S110124, to the plant parts of soybean cultivar S110124, and to methods for producing progeny of soybean cultivar S110124. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S110124. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S110124, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S110124 with another soybean cultivar.
US08759624B1 Soybean variety XBP54005
A novel soybean variety, designated XBP54005 is provided. Also provided are the seeds of soybean variety XBP54005, cells from soybean variety XBP54005, plants of soybean XBP54005, and plant parts of soybean variety XBP54005. Methods provided include producing a soybean plant by crossing soybean variety XBP54005 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XBP54005, methods for producing other soybean varieties or plant parts derived from soybean variety XBP54005, and methods of characterizing soybean variety XBP54005. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP54005 are further provided.
US08759622B2 Cucumbers comprising DNA from PI 250147 conferring closterovirus resistance
A method for producing cucumber plants which are resistant to cucumber closteroviruses. The method comprises the steps of providing a Cucumis sativus plant which contains alleles that confer resistance to the closteroviruses defined by two QTLs, crossing said C. sativus plant with C. sativus culture breeding material, collecting the seeds resulting from said cross, regenerating the seeds into plants, evaluating the plants for resistance to the closteroviruses, and identifying and selecting resistant plants. Further, a resistant cucumber plant produced by the method as well as fruit or seed produced by said plant.
US08759614B2 Use of rice polypeptides for the enhancement of grain size
A method of making a transgenic plant by transforming into a host plant a recombinant DNA construct that expresses in the transgenic plant a rice polypeptide and the transgenic plant thus produced.
US08759613B1 Method of producing a lunasin polypeptide in plants
A method of producing a lunasin polypeptide in a plant includes expressing a fusion protein including the lunasin polypeptide in the plant and cleaving the lunasin polypeptide from the fusion protein.
US08759608B2 Method of creating a spring Brassica napus
Crossing a winter B. napus line with a rapid-cycle B. rapa line has been discovered to provide an unexpectedly simple and efficient way to create a modified B. napus with a spring flowering habit. In one implementation, such a modified B. napus or its progeny is crossed with a second winter B. napus line to produce a plant having a winter flowering habit. This allows one to significantly shorten the development cycle for winter-flowering B. napus lines by conducting part of the breeding program with spring-flowering time cycles, then migrating the resultant germplasm back into a winter-flowering line.
US08759602B2 Method and apparatus for hemostasis
Devices and methods are disclosed for achieving hemostasis in traumatized patients. Such haemostatic packing devices and methods are especially useful in the emergency, trauma surgery or military setting. The patient may have received trauma to abdominal viscera, the thoracic cavity or the periphery. The devices utilize fluid impermeable outer surfaces and distributed pressure to achieve tamponade and hemostasis, primarily by exertion of pressure. The devices come in a variety of configurations including sheet, rolled sheet, folded sheet and polygonal solids including extruded shapes. The devices are capable of serving as carriers for thrombogenic or anti-pathogenic agents. The devices are flexible, bendable, and conformable in their wet or dry state so that they exert distributed pressure on the wound. The hemostatic packing devices may be placed and removed by open surgery or laparoscopic access without generating excessive re-bleeding, and may further comprise antimicrobial or thrombogenic regions.
US08759601B2 Method for biogas treatment and biogas installation
The invention relates to a method for biogas treatment, wherein the gas originating from a fermentation is separated into a usable biogas stream consisting essentially of methane gas and into an exhaust gas stream containing undesired substances, said exhaust gas stream being thermally or catalytically oxidized. According to the invention, the exhaust gas stream is guided prior to oxidation through closed storage containers and/or fermentation residue containers for the inertization of explosive gas concentrations resulting there.
US08759600B2 Reduced fluidization of solid particles in radial flow fluid/solid contacting
Apparatuses and methods are disclosed for contacting radially flowing fluids with solid particles (e.g., catalyst) with reduced tendency for fluidization of the particles, and especially a sealing portion of the particles at the top of a particle retention zone disposed between screens at upstream and downstream positions relative to radial fluid flow. Fluidization is reduced or eliminated by offsetting openings of the screens in the axial direction, such that upstream openings in the upstream screen are above highest downstream openings in a downstream stream. The offset in openings imparts a downward flow component to radially flowing fluid, thereby reducing solid particle fluidization without the need to induce a specific pressure drop profile along the entire axial direction of the screens.
US08759597B2 Methods for producing zeolite catalysts and methods for producing alkylated aromatic compounds using the zeolite catalysts
A method for producing a zeolite catalyst includes mixing a zeolite material with a filler material comprising transition phase and alpha alumina, a porosity enhancing agent, and water to produce a paste; mulling the paste; extruding the paste to produce a shaped extrudate; and drying and calcining the shaped extrudate to produce a zeolite catalyst, wherein the zeolite catalyst has a total porosity greater than about 0.60 ml/gm and greater than 15% of a total pore volume of pores in the range from about 550 Å to about 31,000 Å.
US08759590B2 Indenopyrene compound, organic thin film solar cell material using the same, and organic thin film solar cell
A specified indenopyrene compound containing a disubstituted amino group substituted with a group having a carbon number of from 1 to 40, which is a useful indenopyrene compound as an organic electronics material, and in particular, an indenopyrene compound which when used for organic thin film solar cells, displays a photoelectric conversion characteristic with high efficiency, is provided.
US08759586B2 Processes for the preparation of cinacalcet
The present invention provides processes and intermediates for preparing cinacalcet base and pharmaceutically acceptable salts thereof.
US08759585B2 Two-stage process for cost-effective deposition of homogeneous catalysts in MDA synthesis
The invention provides a process for preparing diphenylmethanediamine, comprising the steps of: a) reacting aniline with formaldehyde in the presence of an acid, b) neutralizing the predominant part of the acid with ammonia and/or aqueous ammonia solution, c) separating the reaction mixture from step b) into an aqueous phase and an organic phase, d) neutralizing the other part of the acid, present in the organic phase, with aqueous alkali metal hydroxide solution, e) separating the reaction mixture from step d) into an aqueous phase and an organic phase, f) treating the aqueous phase obtained in step c) or optionally the combined aqueous phases from steps c) and e) with at least one oxide or hydroxide of an alkaline earth metal, g) removing the ammonia obtained in step f).
US08759582B2 Process for the preparation of lacosamide
Present invention relates to an improved and commercial process for the preparation of lacosamide ((R)-2-acetamido-N-benzyl-3-methoxypropanamide) of formula (I). Present process utilizes high purity crystalline solids of formulae (XXXII) and (XIII) as key intermediates. Lacosamide is indicated for the adjunctive treatment of partial onset seizures in patients aged at least 17 years.
US08759581B2 Method of preparing 1-chloroacetamido-1,3,3,5,5-pentamethylcyclohexane
Method of preparing 1-chloroacetamido-1,3,3,5,5-pentamethylcyclohexane, an intermediate in the synthesis of 1-amino-1,3,3,5,5-pentamethylcyclohexane (Neramexane) or a pharmaceutically acceptable salt thereof, comprising step (iii): (iii) reacting 1-hydroxy-1,3,3,5,5-pentamethylcyclohexane with chloroacetonitrile in the presence of an acid, wherein 1-hydroxy-1,3,3,5,5-pentamethylcyclohexane is employed in step (iii) as obtained in the reaction of a methylmagnesium halide with 3,3,5,5-tetramethylcyclohexanone without having been subjected to a purification step.
US08759580B2 Method for the production of aminoalkane acid amides
The invention relates to a process for preparing aminoalkanamides by reacting cyanoalkanoic esters with a) ammonia or an amine and b) hydrogen in the presence of a catalyst, the reaction with component b) being started simultaneously or not later than a maximum of 100 minutes after commencement of the reaction of the cyanoalkanoic ester with component a).
US08759578B2 Method for manufacturing fluorine-containing imide compound
With this method for manufacturing fluorine-containing imide compounds, a method for manufacturing a fluorine-containing imide compound ((Rf1SO2)(Rf2SO2)NH) is selected which includes reaction of a fluorine-containing sulfonic acid (Rf1SO3H) and a fluorine-containing sulfonamide (Rf2SO2NH) in the presence of thionyl chloride. Wherein, Rf1 and Rf2 are fluorine, or straight-chain or branched perfluoroalkyl groups with a carbon number of 1-4.
US08759575B2 Method for catalytically producing formic acid
The invention relates to a method for catalytically producing formic acid. A polyoxometallate ion, which is used as a catalyst, of the general formula [PMoxVyO40]5− is brought into contact with an alpha-hydroxyaldehyde, an alpha-hydroxycarboxylic acid, a carbohydrate, or a glycoside in a liquid solution at a temperature below 120° C., wherein 6
US08759572B2 Process for the preparation of thyroid hormones and salts thereof
The present invention generally refers to a process for the preparation of L-thyroxine derivatives. More in particular, the present invention relates to a iodination reaction of an aromatic derivative with an appropriate iodinating agent, so to afford the related iodinated compound as disodium salt, which may represent a useful intermediate for the synthesis of the L-thyroxine mono-sodium salt, and the free form thereof.
US08759566B2 Method for producing α-hydroxycarboxylic acid ester
Provided is a process for producing α-hydroxycarboxylic esters from α-hydroxycarboxylic amides and aliphatic alcohols, wherein it is a production process which is inhibited in a production cost and enhanced in a conversion rate and a selectivity and which is industrially advantageous. To be specific, it is a production process for α-hydroxycarboxylic ester characterized by subjecting α-hydroxycarboxylic amide and aliphatic alcohol to a gas phase reaction in the presence of a zirconium dioxide catalyst. A catalyst lifetime is improved to a large extent by using a zirconium dioxide catalyst containing a specific element.
US08759564B2 Amidoacetonitrile compounds having pesticidal activity
Novel amidoacetonitrile compounds and compositions containing the compounds are disclosed. The compounds have pesticidal properties and are suitable for controlling endoparasites on warm-blooded animals.
US08759563B2 Low-impurity organosilicon product as precursor for CVD
The present invention provides an organosilicon composition comprising diethoxymethylsilane, a concentration of dissolved residual chloride, and a concentration of dissolved residual chloride scavenger that does not yield unwanted chloride salt precipitate when combined with another composition comprising diethoxymethylsilane.
US08759562B2 Preparative method and application of Zn(II)-curcumin complex and Zn(II)-curcumin solid dispersions
This invention revealed the preparative method and applications of a Zn(II)-curcumin complex and its solid dispersions. The mass ration of Zn(II)-curcumin complex and polyvinylpyrrolidone (PVP) K30 was 1:1˜1:28. The Zn(II)-curcumin complex was synthesized by mixing equimolar amounts of zinc acetate and curcumin in dry ethanol and refluxing the mixture under a nitrogen atmosphere. The Zn(II)-curcumin complex precipitated, and the solid was separated by filtration and washed several times by water and ethanol to remove any unreacted curcumin and zinc acetate. Zn(II)-curcumin and PVP-k30 were added to absolute ethanol to produce a suspension by cryo-grinding under a nitrogen atmosphere. SDs of Zn(II)-curcumin/PVP were produced with a spray dryer. Zn(II)-curcumin SDs showed predominant effects in curing various senile diseases by tackling disadvantages of curcumin and surmounted the problems of monoindication and unideal therapeutic efficacy general existed in drugs for senile disease treatment. This invention is of simple preparing method and extensive application prospects.
US08759561B2 Catalyst, method of preparing the same, and method of preparing aromatic carbonate from dialkyl carbonate using the same
The present invention provides a catalyst for synthesizing an aromatic carbonate, a method of preparing the same, and a method of preparing an aromatic carbonate from dialkyl carbonate using the catalyst. The catalyst has a unit structure consisting of Formulae 1a, 1b or 1c: wherein R1 is C1-C5 alkyl, R2 is substituted or unsubstituted phenyl.
US08759560B2 Surface-modified zirconia nanocrystal particle and method for producing same
The invention provides a surface-modified zirconia nanocrystal particle, wherein the surface of the zirconia nanoparticle is modified by organic sulfonyloxy groups, and a method of producing a zirconia nanocrystal particle whose surface is modified by carbonyloxy groups, organic phosphoryloxy groups or aryloxy groups. This makes it possible a highly stable surface-modified zirconia nanocrystal particle having a solvent dispersibility by a simple method. Further, it is possible to the surface-modified zirconia nanocrystal particle of the invention is equipped with a surface modifier having a structure that can be easily substituted with a desired functional group according to use. Furthermore, it is possible to the method of producing the surface-modified zirconia nanocrystal particle which is capable of easily producing that.
US08759558B2 Sulphur containing lipids for use as food supplement or as medicament
The present invention relates to lipid compounds of the general formula (I): wherein R1 is selected from a C10-C22 alkyl, a C10-C22 alkenyl having 1-6 double bonds, and a C10-C22alkynyl having 1-6 triple bonds; R2 and R3 are the same or different and may be selected from a group of different substituents; Y is selected from sulphur, sulfoxide, and sulfone; and X represents a carboxylic acid or a derivative thereof, a carboxylic ester, a carboxylic anhydride or a carboxamide; or a pharmaceutically acceptable salt, complex or solvate thereof.The invention also relates to pharmaceutical compositions and lipid compositions comprising such compounds, and to such compounds for use as medicaments or for use in therapy, in particular for the treatment of diseases related to the cardiovascular, metabolic and inflammatory disease area.
US08759552B2 Liquid phase epoxidation process
The present invention provides a continuous process for the epoxidation of an olefinic compound with an oxidant, which process comprises reaction of an olefinic compound with an oxidant in the presence of a catalyst in an apparatus that comprises a reactive distillation column, which column comprises (i) a reactive section, which comprises the catalyst (ii) a rectifying section situated above the reactive section and adapted to allow separation of reagents and/or by-products from products (ix) a stripping section situated below the reactive section and adapted to allow separation of product from reagents and/or by-products (x) a vessel situated below the stripping section and adapted to provide a source of heat for the column and in which initial vaporization of one or more of the reagents can occur, wherein the temperature in the reactive section (i) is a temperature at which the reaction between the olefinic compound and the oxidant takes place and the temperature in the stripping section (iii) is higher than the temperature in the rectifying section (ii).
US08759548B2 S-nitrosoglutathione reductase inhibitors
The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
US08759546B2 Physical nano-complexes for preventing and treating cancer and method for manufacturing the same
The present invention discloses a physical nano-complex for preventing and treating cancer and a method for manufacturing the same. The composition contains EGCG and nanogold, wherein the ratio of the EGCG to the nanogold is in a range from 23:0.5˜23:10 (ppm/ppm). The present invention further discloses a method for manufacturing the composition, wherein the method is to mix the EGCG and the nanogold sufficiently by an ultrasonication process, which makes the EGCG and the nanogold combine to each other well.
US08759544B2 Synthesis of an antiviral compound
The present disclosure provides processes for the preparation of a compound of Formula I: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates to compounds of formula.
US08759543B2 Bithiophene derivatives and semiconductor devices comprising the same
In an embodiment of the disclosure, a bithiophene derivative is provided. The bithiophene derivative has formula (I): In formula (I), R is C8-25 alkyl, and A includes In another embodiment of the disclosure, a semiconductor device including the bithiophene derivative is further provided.
US08759542B2 Process for preparing alpha-carboxamide derivatives
The present application provides a process for the preparation of α-carboxamide pyrrolidine derivatives of formula (I), wherein R1 and R2 are independently hydrogen, C1-6alkyl or C3-6cycloalkylC1-6alkyl; or such R1 and R2, together with the nitrogen to which they are attached, may form an unsubstituted 3-, 4-, 5- or 6-membered saturated ring; X is carbon or nitrogen; n is 0, 1 or 2, wherein when present each R5 is independently selected from the list consisting of C1-3alkyl, halogen, cyano, haloC1-3alkyl, hydroxy, C1-3alkoxy and C1-3haloalkoxy; either R6 or R7 is —O—R8, —OCHR9R8, —NCH2R8 or —(CH2)2R8 wherein the other R6 or R7 is hydrogen or R5; and wherein R8 is a phenyl ring or wherein the phenyl ring is optionally substituted by one or more groups independently selected from the list consisting of C1-3alkyl, halogen, cyano, haloC1-3alkyl, hydroxy, C1-3alkoxy and C1-3haloalkoxy; and R9 is hydrogen or C1-3alkyl.
US08759541B2 Chiral acyclic diaminocarbene ligands, precursors therefore and their use in organic synthesis reactions
The current application relates to a metal catalyst of formula (I): M[ADC][X]n, wherein M is a metal, ADC is a chiral acyclic diaminocarbene ligand, and X is a neutral or anionic ligand. The ADC ligand is prepared from the corresponding chiral formamidium salt precursor. The metal catalyst is used for asymmetric organic synthesis reactions such as hydrosilations, hydrogenations, conjugate additions, and cross-couplings.
US08759539B2 Substituted bicyclic amines for the treatment of diabetes
Described herein are substituted bicyclic amines. In particular, described herein are substituted bicyclic amines that are effective as antagonists of SSTR5 and useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, metabolic syndrome, depression, and anxiety.
US08759535B2 Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof
Substituted fused imidazole derivatives, methods of their preparation, pharmaceutical compositions comprising a substituted fused imidazole derivative, and methods of use in treating inflammation are provided. The substituted fused imidazole derivatives may control the activity or the amount or both the activity and the amount of heme-oxygenase.
US08759531B2 Preparation method of fluoro-substituted deuterated diphenylurea
A fluoro-substituted deuterated diphenylurea compound, especially 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-2-(N-(methyl-d3))picolinamide, preparing method and use for treating or preventing tumor and relative diseases thereof.
US08759530B2 Method for producing phenoxypyridine derivative
A method for producing a compound or a salt thereof represented by a formula (I), comprising reacting a compound or a salt thereof represented by a formula (II) and an aniline derivative represented by a formula (III) in water or a mixed solvent of water and an organic solvent in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide and substantially in the absence of a base is disclosed, wherein R1 is a 4-[3-(dimethylamino)azetidin-1-yl]piperidin-1-yl group, a 4-(4-methylpiperazin-1-yl)piperidin-1-yl group, a 3-hydroxyazetidin-1-yl group or a methyl(1-methylpiperidin-4-yl)amino group, R2, R3, R4 and R5 may be the same or different and are each a hydrogen atom or a fluorine atom, and R6 is a hydrogen atom or a halogen atom.
US08759525B2 Process and intermediates for preparing integrase inhibitors
The invention provides synthetic processes and synthetic intermediates that can be used to prepare 4-oxoquinolone compounds having useful integrase inhibiting properties.
US08759524B2 Production process of optically active 3-quinuclidinol derivative
A process is provided for efficiently producing an optically active 3-quinuclidinol derivative of high optical purity using a readily available ruthenium compound as an asymmetric reduction catalyst. This process is a process for producing an optically active 3-quinuclidinol derivative represented by the following formula (III) comprising asymmetrically hydrogenating a 3-quinuclidinone derivative represented by the following formula (I) in the presence of a ruthenium compound (II) represented by formula (II): Ru(X)(Y)(Px)n[R1R2C*(NR3R4)-A-R5R6C*(NR7R8)] (in the formulas, R represents a hydrogen atom or C7 to C18 aralkyl group and the like, X and Y represent hydrogen atoms or halogen atoms and the like, Px represents a phosphine ligand, n represents 1 or 2, R1 to R8 represent hydrogen atoms or C1 to C20 alkyl groups and the like, * represents an optically active carbon atom and A represents an ethylene group and the like).
US08759523B2 Process for preparing pyrano—[2,3-C]pyridine derivatives
The present invention relates to a process comprising the step of dehydrating a compound of Formula (I): with a suitable dehydrating reagent to form a compound of Formula (II): wherein R1-R7 are as defined herein. Compounds of Formula (II) have shown promise as intermediates to compounds useful for treating bacterial infections.
US08759522B2 Inhibitors of protein tyrosine kinase activity
This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling. The invention also provides compounds, compositions and methods for treating cell proliferative diseases and conditions and opthalmological diseases, disorders and conditions.
US08759518B2 Intermediates for the preparation of HMG CoA reductase inhibitors and processes for the preparation thereof
A compound of Formula (1), is disclosed wherein P1 and P2 are alcohol protecting groups or 1,3-diol protecting group, R is selected from: wherein R4a is selected from alkyl, aryl, arylalkyl and cycloalkyl, Rc is selected from H, alkyl, aryl, alkaoxy, haloalkyl, monohaloalkyloxy, and dihaloalkyloxy, Rd is selected from alkyl, aryl, arylalkyl, CF3, halo and NO2 and X is selected from O, N—H, N-alkyl and S, Ra and Rb are same or different and each represents hydrogen, an alkyl group of 1 to 12 carbon atoms, an aryl group of 6 to 12 carbon atoms, or an aralkyl group of 7 to 12 carbon atoms.
US08759514B2 Method for separation of HMX and RDX
The present invention is directed to a method for effectively separating HMX and RDX from HMX/RDX-included explosives, respectively, without using a harmful organic solvent, the method capable of respectively separating HMX and RDX from HMX/RDX-included explosives by selectively dissolving RDX included in explosives by using a difference between solubility parameters of HMX and RDX with respect to compressed dimethylether. The present invention is further directed to an apparatus for respectively separating HMX and RDX from HMX/RDX-included explosives comprising a dimethylether supplying unit, an explosive particle dissolving unit, and an explosive particle collecting unit.
US08759510B2 Nucleoside cyclicphosphates
Cyclic phosphate of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomers, salts (acid or basic addition salts), hydrates, solvates, or crystalline forms thereof, represented by the following structure:
US08759508B2 Chromophoric silyl protecting groups and their use in the chemical synthesis of oligonucleotides
The compounds are of class of chromophoric 1,2,3-triazolyl equipped silyl linking groups that are useful in the chemical synthesis of RNA. An example of a nucleoside comprising this group is
US08759503B2 Truncated CD20 protein, deltaCD20
Isolated nucleic acid sequence encoding the CD20 gene comprising SEQ ID NO: 5, recombinant vector comprising a nucleic acid sequence placed under the control of one or a plurality of elements required for the expression thereof in a host cell, and method for improving the efficacy of a treatment comprising using a nucleic acid sequence comprising SEQ ID NO: 5.
US08759492B2 Engineered red-shifted channelrhodopsin variants
The invention provides engineered red-shifted channelrhodopsin variants. In some embodiments, the channelrhodopsin variants are characterized by improved membrane trafficking, expression, and/or unique spectral and kinetic properties.
US08759491B2 Modulators of hepatocyte growth factor activator
The invention provides methods and compositions for modulating hepatocyte growth factor activator function.
US08759488B2 High stability streptavidin mutant proteins
The present invention provides a mutant streptavidin subunit which comprises one or more amino acid substitutions compared to a wildtype streptavidin subunit at any one of residue positions equivalent to positions (50, 51, 52, 53) and (54) of SEQ ID NO. 2 and wherein amino acid residues at positions equivalent to positions (23, 27, 43, 45, 49, 79, 88, 90, 92, 108, 110) and (128) of SEQ ID NO. 2, in said mutant streptavidin subunit, are wildtype, wherein (i) when said mutant streptavidin subunit unit is comprised in streptavidin, said streptavidin has a lower off rate for biotin or for a biotin conjugate than wildtype streptavidin or (ii) when said mutant streptavidin subunit is in monomelic form said mutant monomelic streptavidin has a lower off rate for biotin or a biotin conjugate than monomelic streptavidin. The invention also encompasses nucleic acid molecules comprising a nucleotide sequence encoding the mutant streptavidin subunit and vectors and cells comprising the nucleic acid. Further, methods of capturing biotinylated molecules and cells and therapeutic methods are encompassed.
US08759485B2 Chemokine binding activity of viral TNF receptors and related proteins
Chemokine binding activity of viral TNF receptors and related proteins. The invention relates to a C-terminal domain (CTD) of viral tumor necrosis factor receptors (vTNFRs) CrmB or CrmD or CTD homologues (CTD1, CTD2 and CTD3) from poxvirus and their functional homologues, including derivatives, and fragments, for use in binding chemokines and their analogues and/or to enhance the immunomodulatory properties of TNFRs or in blocking binding of chemokines to their corresponding cell surface receptors and/or to modulate chemokine biological activity.
US08759475B2 Continuous production of polyamides
Polyamides, e.g., polyhexamethylene adipamide, are continuously produced via the following stages: Stage 1: into and through a reactor, polycondensing a liquid stream which contain the polyamide monomer(s) at a pressure P1 greater than atmospheric pressure, the stream of material at the outlet of the reactor including a vapor phase which contains steam and a liquid phase which at least contains the product of polycondensation; Stage 2: feeding the outlet stream of material into a chamber, evacuating at least a portion of the vapor phase therefrom and recovering at least the liquid phase which at least contains the product of polycondensation, the pressure P2 in the chamber being regulated at a set value such that it is greater than atmospheric pressure and the residence time of said liquid phase in the chamber being less than 5 minutes; and Stage 3: pressure reducing at least the liquid phase which at least contains the stream of polycondensation product recovered during Stage 2.
US08759474B2 Method for producing liquid crystal polyester
Disclosed is a method for producing a liquid crystal polyester, which includes the steps of:(1) polycondensing a mixture of 70.5 to 71.5 mol % of a compound represented by the defined formula (I) (for example, 4-acetoxybenzoic acid) with 28.5 to 29.5 mol % of a compound represented by the defined formula (II) (for example, 6-acetoxy-2-naphthoic acid) to form a prepolymer, wherein the prepolymer has a flow initiation temperature of 200° C. or higher, and the mixture is polycondensed until reaching the temperature which is at least 30° C. lower than the polycondensation temperature; (2) removing the prepolymer in a molten state, followed by solidification and further grinding to produce prepolymer particles; and (3) subjecting the prepolymer particles to a heat treatment at 200 to 310° C. under circulation of an inert gas while remaining in a solid phase state.
US08759469B2 Synthesis of urethanes and polyurethanes catalysed by carbenes
The present invention relates to a process for preparing a compound comprising at least a urethane group —HN—C(═O)—O, said process comprising a step (E) in which a compound (I) comprising at least an isocyanate functional group —N═C═O is reacted with an organic compound (II) carrying at least a hydroxyl group —OH, said reaction being carried out in a presence of a carbene (III) used as a catalyst.
US08759468B2 Silicone resin with improved barrier properties
The moisture and gas barrier properties of an organopolysiloxane having at least two substituents which are able to undergo crosslinking reactions per molecule shall be improved. This is achieved by providing an organopolysiloxane wherein at least 10 mol % of all substituents are represented by formula (1) wherein q is an integer from 0 to 5 and R1, R2, R3 each independently are methyl or ethyl groups. Furthermore, the invention is directed to a composition based on the aforementioned organopolysiloxane and to the use of the organopolysiloxane and of the composition.
US08759465B2 Cross-linkable polymeric compositions
A class of bioinspired, cross linking polymers, created by working catechol functionalities into the backbone of a bulk polymer, is disclosed. Varied cross linking groups may be incorporated into different polymer backbones, and subsequently reacted with an array of reagents. An adhesive composition comprising a copolymer, the copolymer comprising pendant dihydroxyphenyl groups; and a crosslinking agent selected from the group consisting of, for example, oxidants, enzymes, metals, and light. A method of preparing an adhesive composition comprising copolymerizing a first monomer comprising pendant dihydroxy-protected dihydroxyphenyl groups; deprotecting the dihydroxy-protected dihydroxyphenyl groups; crosslinking the dihydroxyphenyl groups with a crosslinking agent.
US08759461B2 Post metallocene-type transition metal compounds
The present invention relates to a novel post metallocene-type ligand compound, to a metal compound containing the ligand compound, to a catalytic composition containing the metal compound, and to a method for preparing same, as well as to a method for preparing olefin polymers using the catalytic composition. The present invention provides a catalyst for preparing special polyolefin-based polymers having excellent activity.
US08759439B2 Tire tread rubber composition
A tire tread rubber composition includes: diene rubber containing three kinds of rubber (E-SBR, modified S-SBR, and natural rubber (NR)) in a total amount of 80% by weight or more; and a filler in an amount of 100 to 140 parts by weight based on 100 parts by weight of the diene rubber, the filler containing 70% by weight or more of silica, wherein the diene rubber contains 10 to 25% by weight of the natural rubber, the weight ratio of the three kinds of rubber (E-SBR:modified S-SBR:NR) is 1 to 2:2.5 to 4:1, the styrene content of the E-SBR and the modified S-SBR is 35 to 40% by weight, and the difference between the glass transition temperature of the E-SBR and the glass transition temperature of the modified S-SBR is 10° C. or lower.
US08759436B2 Transparent color coating composition containing nanosize dispersed pigments, coated substrate and method for preparing same
The present invention relates to a transparent color coating composition containing nano-sized dispersed pigments, to a coated substrate, and to a method for preparing the same. When used in coating glass, the transparent color coating composition expresses a variety of colors, maintains continuous color transparency, gives sun protection to glass, and has superior adhesion, solvent resistance, and sun protection properties.
US08759433B2 Aromatic polycarbonate composition
The present invention relates to a polymer composition comprising the following components: a) 76.6-99.49 mass % of aromatic polycarbonate, b) 0.5-20 mass % of laser direct structuring additive, c) 0-2.4 mass % of rubber like polymer, and d) 0.01-1 mass % of acid and/or acid salt wherein the mass % is calculated relative to the sum of a), b), c) and d). The invention also relates to a moulded part containing this composition, to a circuit carrier containing such moulded part and to a process for producing such circuit carrier.
US08759431B2 Durable polyoxymethylene composition
A durable polyoxymethylene composition includes a polyoxymethylene copolymer with 1,3-dioxolane as a comonomer, a lubricant, an inorganic filler, a nucleating agent including a sodium salt, a stabilizer, an anti-static agent. A ramp is made of the durable polyoxymethylene. The ramp and the durable polyoxymethylene have excellent micro-wear-resistant property.
US08759424B2 Coated biodegradable building article
A composite material includes a matrix composed of a polyhydroxyalkanoate (PHA) polymer and a filler composed of particles dispersed in the matrix. The particles are composed of naturally-derived materials (e.g., ground bone meal or pumice powder), have a microporous microstructure, have a low hygroscopic expansion, and are less than 1.0 mm in size. Preferably, the matrix and the filler together constitute 100% by weight of the composite material, and at most 30% by volume of the composite material is consumed by the filler. The composite material may take the form of an anaerobically biodegradable article of manufacture such as a building material a coating of a building material or other article.
US08759420B2 Marble chips for an artificial marble, method of making the same, and artificial marble including the same
The present invention provides marble chips produced by hardening or molding a resin composition including a binder and a reactive monomer, wherein the binder comprises a halogenated alkoxylated diacrylate oligomer. The marble chips of the present invention can be formed into a uniform pattern, so that an artificial marble made using the marble chips of the present invention may have an outer appearance and texture similar to that of engineered stone.
US08759419B2 Water-based ink for ink-jet recording and cartridge
A water-based ink for ink-jet recording includes a self-dispersible pigment modified by phosphate group; water; a water-soluble organic solvent; at least one of a cationic polymer and basic amino acid; and at least one selected from the group consisting of boric acids, a chelate agent, a reducing sugar and a sugar alcohol.
US08759416B2 Hindered primary chlorinated amine in a latex formulation
The present invention relates to a process comprising adding a sufficient amount of a halamine with a latex binder to achieve microbial prophylaxis, wherein the halamine is characterized by the following formula: wherein X1 is H, Br, or Cl; X2 is Br or Cl; and R1 is H or a C1-30 alkyl group or mixtures thereof. The present invention also relates to a composition comprising the halamine and a latex binder. The present invention provides a quick kill shelf stable preservative for latex binders and for formulations that use such binders.
US08759413B2 Lanthanum containing novel polyacrylate for optical lenses
A process for the preparation of lanthanum containing polyacrylates for optical applications. The process consists in dispersing lanthanum oxide in acrylic acid to form a monomer mixture. An aromatic carboxylic acid is added to the monomer mixture and then a cross linking agent is added thereto. Such a monomer mixture is subjected to the step of polymerization by gamma radiation.
US08759408B2 Tire vulcanization/retreading system using autoclave with electromagnetic induction heating
Tire vulcanizing/retreading and de-vulcanization system including an autoclave and heating based on an induction system, which will lead to vulcanization or de-vulcanization of a tire.
US08759407B2 Method for producing synthetic natural gas
Process for producing synthetic natural gas (SNG) which is provided in an energy-efficient way at the inlet pressure into a downstream pipeline system. For this purpose, a synthesis gas containing carbon oxides and hydrogen is converted into a product gas rich in methane by multi-stage catalytic methanation in a main reaction zone and a post-reaction zone, wherein the adjustment of the target pressure is effected by compression before the main reaction zone and/or before or in the post-reaction zone.
US08759405B2 Stevia extract or steviol for hair care
Methods of enhancing the appearance of a mammal's hair/fur are provided by the administration of an oral nutraceutical or food composition comprising steviol or a steviol precursor, without chromene, for a time sufficient and in an amount effective to enhance the overall appearance of the mammal's hair/fur. The enhancement of the appearance of the mammal's hair/fur includes restoring hair/fur color, lessening hair loss, increasing the thickness of hair, counteracting age-associated hair thinning, and delaying the onset or severity of age-associated hair loss and thinning. A nutraceutical or food which includes steviol or a steviol precursor in an amount sufficient to enhance the overall appearance of a mammal's hair/fur is also provided.
US08759403B2 Curcuminoids and its metabolites for the application in allergic ocular/nasal conditions
A pharmaceutical composition for nasal administration comprising: a nanoemulsified curcumin component; a liquid medium for the curcumin component; and a pharmaceutically acceptable excipient. The curcumin component is a natural curcuminoid, a synthetic curcuminoid, a metabolite of a natural or synthetic curcuminoid, or a mixture thereof. The excipient is effective in increasing the bioavailability of the curcumin component.
US08759401B2 Aqueous gel formulation and method for inducing topical anesthesia
Disclosed is a stable aqueous gel formulation suitable for topical use comprising water, an anesthetic (e.g., lidocaine hydrochloride), a viscoelastic polymer, and a tonicity modifier, wherein the aqueous gel formulation is free of preservatives and phosphate buffer, is isotonic with physiological fluids, and is sterile and has low particulate count. Also disclosed is a method of inducing topical anesthesia on a tissue or organ, e.g., the eye, of an animal comprising providing a stable aqueous gel formulation comprising water, an anesthetic, a viscoelastic polymer, and a tonicity modifier, wherein the aqueous gel formulation is free of preservatives and phosphate buffer, is isotonic with physiological fluids, and is sterile, and topically administering an effective amount of the aqueous gel formulation to the tissue or organ of the animal.
US08759397B2 Detergent composition
The present invention provides a salt of ethylenediamine disuccinic acid comprising at least 1.6 mole of alkaline earth metal per mole of ethylenediamine disuccinic acid. Salts of the invention have been found to be useful in providing compositions comprising hydrogen peroxide having improved stability.
US08759394B2 4-hydroxybutyric acid analogs
This invention relates to novel derivatives of 4-hydroxybutyric acid and prodrugs thereof, and pharmaceutically acceptable salts of the foregoing. This invention also provides pharmaceutical compositions comprising a compound of this invention and the use of such compositions in methods of treating narcolepsy, fibromyalgia, other disorders or conditions that are beneficially treated by improving nocturnal sleep or by administering sodium oxybate.
US08759392B2 Amides as inhibitors of human secreted phospholipase A2
Methods and compounds useful for inhibiting a phoshpolipase A2 are provided, the methods comprising contacting the phoshpolipase A2 with a compound having the structure A, or pharmaceutically acceptable salts thereof: wherein R1 is H, F, NH2, or COOH; R2 is, H, linear saturated or unsaturated alkyl, alkenyl, or alkynyl; each of R3 and R4 is independently H, linear saturated or unsaturated alkyl, alkenyl, alkynyl, phenyl, or substituted phenyl; R5 is H, (C1-C6) alkyl such as methyl or ethyl; X is aryl or substituted aryl, such as phenyl or a substituted phenyl; and Y is O or S.
US08759385B2 Composition comprising azole fungicide and water soluble metal salt
Hair treatment composition comprising an azole fungicide and zinc gluconate and wherein the composition does not comprise Trichogen®.
US08759384B2 Oxo-imidazolyl compounds
Compounds represented by Formula I and II, or pharmaceutically acceptable salts thereof: inhibit bacterial 2-epimerase and are useful anti-infective agents.
US08759382B2 Propargyl-trifluoromethoxy-aminobenzothiazole derivatives, their preparation and use
Disclosed are novel derivatives of propargyl-trifluoromethoxy-amino-benzothiazole which are effective in treating neurologic disorders, including Parkinson's disease and multiple sclerosis.
US08759381B1 Two-photon absorbing water soluble fluorescent probe as a near-neutral pH indicator
Disclosed are fluorescent compounds useful as intracellular pH probes. In particular, the invention teaches a two-photon absorbing, water soluble, fluorescent compound, a fluorene derivative, which is effective as a near-neutral pH indicator and particularly as an intracellular probe. A method for chemical synthesis of the claimed compounds is provided.
US08759378B2 Methods for treating blood disorders
Methods of treating blood disorders are described.
US08759375B2 Methods for treating multiple myeloma using 4-(amino)-2-(2,6-dioxo(3-piperidyl))-isoindoline-1,3-dione in combination with proteasome inhibitor
Methods of treating, preventing and/or managing cancer as well as and diseases and disorders associated with, or characterized by, undesired angiogenesis are disclosed. Specific methods encompass the administration of an immunomodulatory compound alone or in combination with a second active ingredient. The invention further relates to methods of reducing or avoiding adverse side effects associated with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy which comprise the administration of an immunomodulatory compound. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.
US08759374B2 Certain chemical entities, compositions, and methods
Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
US08759369B2 Inhalable solid amorphous particles comprising tiotropium bromide and a co-solid
An inhalable medicament is provided, in particular a new solid-state form of tiotropium bromide. The medicament can be in the form of solid amorphous particles containing an intimate admixture of tiotropium bromide together with a pharmaceutically acceptable co-solid having a glass transition temperature of at least −50° C., such as a sugar and/or sugar alcohol.
US08759367B2 Compounds and methods for the prevention and treatment of cancer
The present invention relates to compounds for modulating sonic hedgehog signaling and preventing or treating cancer.
US08759366B2 Aminopyrimidines as SYK inhibitors
The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.
US08759365B2 Organic compounds
The present invention provides a compound of formula (I): wherein the variants R1, R2, R3, R4, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.
US08759362B2 Bicycloheteroaryl compounds and their use as TRPV1 ligands
The invention relates to compounds of formula I and pharmaceutically acceptable derivatives thereof, compositions comprising an effective amount of a compound of formula I or a pharmaceutically acceptable derivative thereof, and methods for treating or preventing a condition such as pain, UI, an ulcer, IBD and IBS, comprising administering to an animal in need thereof an effective amount of a compound of formula I or a pharmaceutically acceptable derivative thereof.
US08759360B2 Purine compounds
A compound of the formula: and pharmaceutical compositions for the treatment or prevention of pain.
US08759359B2 Substituted heteroaryl fused derivatives as PI3K inhibitors
The present invention provides fused derivatives of Formula I: that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.
US08759355B2 Aryl pyrimidine derivatives, preparation methods and pharmaceutical uses thereof
The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or solvate thereof. Various substituents in the formula (I) are as defined in the specification. The present invention also relates to a pharmaceutical composition comprising the compound of formula (I), the preparation method of compound of formula (I), and the use of the compound for the preparation of a medicament for treating and/or preventing human peroxisome proliferators activated receptor δ (hPPARδ)-associated diseases and risk factors.
US08759350B2 Carbostyril derivatives and serotonin reuptake inhibitors for treatment of mood disorders
The pharmaceutical composition of the present invention comprises (1) a carbostyril derivative and (2) a serotonin reuptake inhibitor in a pharmaceutically acceptable carrier. The carbostyril derivative may be aripiprazole or a metabolite thereof, which is a dopamine-serotonin system stabilizer. The serotonin reuptake inhibitor may be fluoxetine, duloxetine, venlafaxine, milnacipran, citalopram, fluvoxamine, paroxetine, sertraline or escitalopram. The pharmaceutical composition of the present invention is useful for treating patients with mood disorders, particularly depression or major depressive disorder.
US08759346B2 Organic compounds
The present invention relates to compounds of formula (I) wherein n represents 0, 1, 2, 3, 4 or 5, R represents independent from each other hydroxyl, cyano, nitro, halogen, alkyl, alkoxy alkylcarbonyl, alkoxycarbonyl, alkylamine, dialkylamine, alkylcarbonylamine, alkylcarbamate Y represents one of the following groups: (Ia) in free base or acid addition salt form, to processes for their production, to pharmaceutical compositions comprising them and their use in the manufacture of a medicament for the treatment and/or delay of progression of psychotic and neurodegenerative disorders.
US08759345B2 Benzoimidazoles as prolyl hydroxylase inhibitors
The present invention is directed to benzoimidazole compounds of the formula (1) and enantiomers, diastereomers, racemates, and pharmaceutically acceptable salts thereof. Compounds of the present invention are useful in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions modulated by prolyl hydroxylase activity.
US08759344B2 Imidazopyridine derivatives, process for preparation thereof and therapeutic use thereof
The invention relates to compounds corresponding to formula (I): in which R2 and R3 together form, with the carbon atoms of the phenyl nucleus to which they are attached, a 6-membered nitrogenous heterocycle corresponding to one of formula (A), (B) or (C) below: in which the wavy lines represent the phenyl nucleus to which R2 and R3 are attached. Preparation process and therapeutic use.
US08759342B2 Benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one urotensin II receptor antagonists
The invention is directed to benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one Urotensin II receptor antagonists useful in treating or ameliorating a Urotensin-II mediated disorder. More specifically, the present invention relates to certain novel benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one compounds and methods for preparing compounds, compositions, intermediates and derivatives thereof. Pharmaceutical compositions and methods for treating or ameliorating a Urotensin-II mediated disorder using compounds of the invention are also described.
US08759341B2 Bi- and tricyclic indazole-substituted 1,4-dihydropyridine derivatives and uses thereof
This invention relates to novel bi- and tricyclic indazole-substituted 1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders.
US08759335B2 Modulators of ATP-binding cassette transporters
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
US08759329B2 Testosterone gel and method of use
The present invention relates to an improved transdermal hydroalcoholic testosterone gen formulation that provides, among other things, a desirable pharmacokinetic hormone profile, and methods of use.
US08759327B2 Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism
The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels.
US08759324B2 Method of activation of oxazaphosphorines
The present invention provides a method of hydroxylating or oxidizing a compound of interest in a subject (e.g., a cytotoxic oxazaphosphorine prodrug), by administering the compound of interest to the subject; and concurrently administering the subject a metalloporphyrin in an amount effective to hydroxylate or oxidize the compound of interest in the subject.
US08759319B2 Lipid composition for improving brain function
The invention pertains to the use of a lipid fraction for the support of brain function. The lipid fraction comprises the medium-chain fatty acids at least 4 g hexanoic acid and/or at least 5 g octanoic acid, at least 1 g eicosapentaenoic acid, and in addition more than 0.4 g α-linolenic acid per 100 g fatty acids of the lipid fraction.
US08759314B2 Methods for treating multiple sclerosis using antisense oligonucleotides
A method for treating a patient suffering from multiple sclerosis, particularly a relapsing form of multiple sclerosis, comprising periodically administering a pharmaceutical composition comprising a therapeutically effective amount of OLIGONUCLEOTIDE 1 to the patient, thereby treating the patient.
US08759304B2 Compositions and methods for increasing telomerase activity
The present invention relates to methods and compositions for increasing telomerase activity in cells. Such compositions include pharmaceutical, including topical, and nutraceutical formulations. The methods and compositions are useful for treating diseases subject to treatment by an increase in telomerase activity in cells or tissue of a patient, such as, for example, HIV infection, various degenerative diseases, and acute or chronic skin ailments. They are also useful for enhancing replicative capacity of cells in culture, as in ex vivo cell therapy and proliferation of stem cells.
US08759303B2 Compositions and methods for treating myelodysplastic syndrome
This invention generally relates to compositions and methods for treating myelodysplastic syndrome. In one embodiment, this invention relates to methods for treating myelodysplastic syndrome with ezatiostat or a salt thereof and lenalidomide.
US08759300B2 Polypeptides and methods of use
Described herein are fragments of fibronectin and vitronectin and variants thereof that have certain activities, including growth factor-binding activity. Also described are fragments of growth factors that bind to fibronectin and inhibit binding of full-length growth factors to fibronectin. Compositions containing such fragments are useful in cosmetic treatments (e.g., the treatment of wrinkles or UV photodamage of skin), and the treatment of wounds and cancer.
US08759299B2 Analogues of insulin-like growth factor-1 (IGF-1) having amino acid substitution at position 59
The present invention relates to novel analogues of insulin-like growth factor-1 (IGF-1), pharmaceutical compositions containing said analogues, and the use of said analogues for treatment of IGF-1-receptor mediated conditions, such as short stature, diabetes therapy, neurodegenerative disease treatment, and cartilage repair. More particularly, the present invention relates to novel analogues of IGF-1 having an amino acid substitution at position 59, e.g., (Asn59)hIGF-1(1-70)-OH (SEQ ID NO:1), and other substitution(s) as defined herein.
US08759298B2 Protein therapy for corneal inflammation, epithelial wound healing, and photoreceptor degeneration
The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties, and their application in the treatment of eye disease, particularly diseases of the retina. In particular aspects, the invention includes administration of a therapeutic polypeptide such as a stanniocalcin family member protein for the treatment of an eye disease. Also included are fusion proteins and cells stimulated or modified to express the therapeutic polypeptides as set forth herein.
US08759297B2 Genetically encoded multifunctional compositions bidirectionally transported between peripheral blood and the cns
Provided herein are compositions for increasing transport of agents across the blood-brain barrier, in some embodiments in both directions, while allowing their activity once across the barrier to remain substantially intact. The agents are transported across the blood-brain barrier via one or more endogenous receptor-mediated transport systems. In some embodiments the agents are therapeutic, diagnostic, or research agent. Also provided herein are nucleic acids encoding proteins contained in the compositions.
US08759295B2 Peptide-peptidase inhibitor conjugates and methods of using same
Peptide-peptidase inhibitor conjugate molecules are disclosed. These conjugate molecules are useful as agents for the treatment and prevention of metabolic and cardiovascular diseases, disorders, and conditions. Such diseases, conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, insulin-resistance, obesity, and diabetes mellitus of any kind, and other diabetes-related disorders.
US08759291B2 Methods of treatment using exendin peptides or GLP-1 peptides
Methods for increasing urine flow are disclosed, comprising administration of an effective amount of GLP-1, an exendin, or an exendin or GLP-1 agonist. Methods for increasing urinary sodium excretion and decreasing urinary potassium concentration are also disclosed. The methods are useful for treating conditions or disorders associated with toxic hypervolemia, such as renal failure, congestive heart failure, nephrotic syndrome, cirrhosis, pulmonary edema, and hypertension. The present invention also relates to methods for inducing an inotropic response comprising administration of an effective amount of GLP-1, an exendin, or an exendin or GLP-1 agonist. These methods are useful for treating conditions or disorders that can be alleviated by an increase in cardiac contractility such as congestive heart failure. Pharmaceutical compositions for use in the methods of the invention are also disclosed.
US08759290B2 Oral glucagon-like peptide conjugates for metabolic diseases
The present invention relates to the field of metabolic compound conjugates, methods of forming said conjugates and uses of these conjugates in the treatment of diabetes and conditions related to this condition. The metabolic compound conjugates of this invention include a metabolic peptide having a glucagon-like peptide (GLP-1) receptor binding motif for action on a GLP-1 receptor and at least one oligomer conjugation site for binding with at least one oligomer, wherein the oligomer includes a polyethylene glycol moiety (PEG), and/or alkyl moiety.
US08759289B2 Method for sensitizing cancer stem cells to cancer therapy
Disclosed herein are compositions and methods useful for the treatment of cancer, such as breast cancer. In some embodiments, the methods and compositions include human prolactin, or human prolactin in conjunction with a cytotoxic agent. In other embodiments, the methods and compositions include one or more of human prolactin, growth hormone and placental lactogen, or one or more of human prolactin, growth hormone and placental lactogen in conjunction with a cytotoxic agent. In some embodiments, the cytotoxic agent comprises a chemotherapeutic agent.
US08759284B2 Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade within the wall to release the drug to produce a therapeutic effect. The preparation can be coupled to an actuator having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.
US08759280B2 Method for producing trimethylcyclododecatriene
The present invention relates to the preparation of trimethylcyclododecatriene in a continuous or batchwise process by trimerizing isoprene in the presence of a catalyst system and of a solvent. It is possible to isolate the resulting crude trimethylcyclododecatriene by means of distillation. The dimethylcyclooctadiene formed as a by-product may likewise be isolated from the crude product.
US08759279B2 Fragranced biodegradable film
A film formed from a biodegradable polymer matrix within which is contained at least one fragrance is provided. The ability to incorporate a fragrance into the polymer matrix is achieved in the present invention by controlling a variety of aspects of the film construction, including the nature of the fragrance, the nature of the biodegradable polymer, the manner in which the polymer matrix and fragrance are melt processed, etc. For example, the fragrance may be injected directly into the extruder and melt blended with the biodegradable polymer. In this manner, the costly and time-consuming steps of pre-encapsulation or pre-compounding of the fragrance into a masterbatch are not required. Furthermore, to obtain a balance between the ability of the fragrance to release the desired odor during use and likewise to minimize the premature exhaustion of the odor during melt processing, the fragrance is selected to have a boiling point (at atmospheric pressure) within a certain range, such as from about 125° C. to about 350° C.
US08759271B2 Liquid detergent composition for improved shine
A liquid detergent composition having a modified polyethyleneimine polymer and a surfactant to provide improved shine on hard surfaces.
US08759270B2 Liquid detergent composition with abrasive particles
The present invention relates to a dishwashing composition comprising abrasive particles and a suspending aid selected from the group consisting of crystalline wax structurants, micro-fibril-cellulose, amido-gellants, di-benzylidene polyol acetal derivatives, and mixtures thereof, and the process and use thereof.
US08759265B2 Thermally stable subsea control hydraulic fluid compositions
An aqueous hydraulic fluid composition comprising of one or more lubricants such as a monovalent metal salt, ammonium, or alkanolamine salt of a dicarboxylic acid, such as a C21 dicarboxylic acid is described in which the aqueous hydraulic fluid composition demonstrates increased thermal stability when exposed to elevated temperatures for a prolonged period of time while being able to tolerate the presence of 10% v/v synthetic seawater. The aqueous hydraulic fluid composition contains less than about 20% by weight (preferably none or substantially none) of an oil selected from the group consisting of mineral oils, synthetic hydrocarbon oils, and mixtures thereof.
US08759263B2 Use of O/W emulsions for chain lubrication
The invention relates to the use of an O/W emulsion, in particular a PIT emulsion, for lubricating conveyor belt systems in food industries as well as a lubricant concentrate based on an O/W emulsion, in particular a PIT emulsion, of wax esters.
US08759261B2 Method and composition for enhanced hydrocarbons recovery
The present invention provides a method of treating a hydrocarbon containing formation comprising (a) providing a hydrocarbon recovery composition to at least a portion of the hydrocarbon containing formation, wherein the composition comprises one or more internal olefin sulfonates having 17 or more carbon atoms, (b) adding water and/or brine from the hydrocarbon formation to the composition, (c) adding a solubilizer which comprises an ethoxylated alcohol wherein the alcohol before ethoxylation had an average molecular weight of at least about 220 and (d) allowing the composition to interact with hydrocarbons in the hydrocarbon containing formation. The solubilizer may comprise less than about 0.1 wt %, preferably from about 0.02 to about 0.05 wt %, of the total composition and it may have from about 5 to about 9 moles of ethylene oxide per mole of alcohol.
US08759252B1 Material and method for the sorption of hydrogen sulfide
The various embodiments of the invention relates to the composition of a hydrogen sulfide capture material and the related method of manufacture. The hydrogen sulfide capture material is formed by solubilizing an iron source in acid to form an aqueous solution comprising iron chloride, neutralizing the aqueous solution with a caustic solution to form a neutralized solution, washing the neutralized solution to separate it into water and a slurry, forming a thickened slurry by removing additional water from the slurry, separating the thickened slurry to produce filtered water and a wet filter cake, and drying the wet filter cake to form granules. The hydrogen sulfide capture material of the present invention removes hydrogen sulfide for a longer time and at a faster rate than the materials of the prior art, thereby improving the efficiency and decreasing the cost of sour gas treatment.
US08759250B2 Composite adsorbent material
The invention is directed to shaped composite adsorbent material, comprising particulate activated carbon material, bound by a suitable binder, preferably selected from the group of sodium alginate calcium alginate, chitosan, polyacrylamide, polyethylene oxide and mixtures thereof, more in particular a combination of chitosan and alginate, whereby the activation of the carbon material has taken place before binding the material.
US08759245B2 Method for preparing porous organic-inorganic hybrid materials, porous organic-inorganic hybrid materials obtained by the method and catalytic uses of the materials
The present invention relates to a method for preparing iron-containing porous organic-inorganic hybrid materials where the organic compound ligand is bonded to a central metal and has a large surface area and pores of molecular size or nano size, by irradiating microwaves instead of heat treatments such as the conventional electric heating, etc. as the heat source of the hydrothermal or solvothermal synthesis reaction, after reacting a metal or metal salt and organic compound to form crystal nuclei by a predetermined pre-treatment operation in the presence of a solvent. In another aspect, a method of the present invention further comprises the step of purifying the obtained porous organic-inorganic hybrid materials by treating them with inorganic salt. In particular, a method of the present invention is characterized by not using a hydrofluoric acid.
US08759243B2 Multi-component catalyst systems and polymerization processes for forming in-situ heterophasic copolymers and/or varying the xylene solubles content of polyolefins
Embodiments of the invention generally include multi-component catalyst systems, polymerization processes and heterophasic copolymers formed by the processes. The multi-component catalyst system generally includes a first catalyst component selected from Ziegler-Natta catalyst systems including a diether internal electron donor and a metallocene catalyst represented by the general formula XCpACpBMAn, wherein X is a structural bridge, CpA and CpB each denote a cyclopentadienyl group or derivatives thereof, each being the same or different and which may be either substituted or unsubstituted, M is a transition metal and A is an alkyl, hydrocarbyl or halogen group and n is an integer between 0 and 4. The multi-component catalyst system further includes a second catalyst component generally represented by the formula XCpACpBMAn, wherein X is a structural bridge, CpA and CpB each denote a cyclopentadienyl group or derivatives thereof, each being the same or different and which may be either substituted or unsubstituted, M is a transition metal and A is an alkyl, hydrocarbyl or halogen group and n is an integer between 0 and 4 and wherein the second catalyst component exhibits a higher ethylene response than the first catalyst component.
US08759242B2 Hydroprocessing catalysts and methods for making thereof
An improved slurry catalyst feed system for heavy oil upgraded is provided. The catalyst feed system comprises a fresh slurry catalyst and a deoiled spent catalyst, with the deoiled spent catalyst being present in an amount of at least 10% the catalyst feed system. The deoiled spent catalyst is a slurry catalyst that has been used in a hydroprocessing operation resulting in than 80% but more than 10% of original catalytic activity, and containing less than 10 wt. % soluble hydrocarbons as unconverted heavy oil feed. The deoiled spent catalyst is slurried in a hydrocarbon medium as dispersed particles prior to being fed to the heavy oil upgrade system.
US08759241B2 Method for making a catalyst composition
A method for making a catalyst composition suitable for various purposes, such as the reduction of nitrogen oxides, is provided. The method includes combining dawsonite or a dawsonite derivative with a catalytic active element.
US08759231B2 Silicon texture formulations with diol additives and methods of using the formulations
The present disclosure includes a texture formulation that includes an aliphatic diol, an alkaline compound and water which provides a consistent textured region across a silicon surface suitable for solar cell applications. Processes for texturing a crystalline silicon substrate using these formulations are also described.
US08759229B2 Method for manufacturing epitaxial wafer
A method for manufacturing an epitaxial wafer that can reduce occurrence of a surface defect or a slip formed on an epitaxial layer is provided. The manufacturing method is characterized by comprising: a smoothing step of controlling application of an etchant to a wafer surface in accordance with a surface shape of a silicon wafer to smooth the wafer surface; and an epitaxial layer forming step of forming an epitaxial layer formed of a silicon single crystal on the surface of the wafer based on epitaxial growth.
US08759227B2 Method for processing a target object
A method for processing a target object includes arranging a first electrode and a second electrode for supporting the target object in parallel to each other in a processing chamber and processing the target object supported by the second electrode by using a plasma of a processing gas supplied into the processing chamber, the plasma being generated between the first electrode and the second electrode by applying a high frequency power between the first electrode and the second electrode. The target object includes an organic film and a photoresist layer formed on the organic film. The processing gas contains H2 gas, and the organic film is etched by a plasma containing H2 by using the photoresist layer as a mask while applying a negative DC voltage to the first electrode.
US08759226B2 Method for minimizing contamination in semiconductor processing chamber
A semiconductor processing apparatus includes a reaction chamber, a loading chamber, a movable support, a drive mechanism, and a control system. The reaction chamber includes a baseplate. The baseplate includes an opening. The movable support is configured to hold a workpiece. The drive mechanism is configured to move a workpiece held on the support towards the opening of the baseplate into a processing position. The control system is configured to create a positive pressure gradient between the reaction chamber and the loading chamber while the workpiece support is in motion. Purge gases flow from the reaction chamber into the loading chamber while the workpiece support is in motion. The control system is configured to create a negative pressure gradient between the reaction chamber and the loading chamber while the workpiece is being processed. Purge gases can flow from the loading chamber into the reaction chamber while the workpiece support is in the processing position, unless the reaction chamber is sealed from the loading chamber in the processing position.
US08759225B2 Method to form a CMOS image sensor
The present disclosure relates to a method and composition to limit crystalline defects introduced in a semiconductor device during ion implantation. A high-temperature low dosage implant is performed utilizing a tri-layer photoresist which maintains the crystalline structure of the semiconductor device while limiting defect formation within the semiconductor device. The tri-layer photoresist comprises a layer of spin-on carbon deposited onto a substrate, a layer of silicon containing hard-mask formed above the layer of spin-on carbon, and a layer of photoresist formed above the layer of silicon containing hard-mask. A pattern formed in the layer of photoresist is sequentially transferred to the silicon containing hard-mask, then to the spin-on carbon, and defines an area of the substrate to be selectively implanted with ions.
US08759220B1 Patterning process
A patterning process includes (1) forming, on a body to be processed on which a titanium-containing hard mask is formed, an organic underlayer film; (2) forming, on the organic underlayer film, a titanium-containing resist underlayer film having a titanium content of 10% to 60% by mass; (3) forming a photoresist film on the titanium-containing resist underlayer film; (4) forming a photoresist pattern by exposing the photoresist film and developing; (5) pattern-transferring onto the titanium-containing resist underlayer film by using the photoresist pattern as a mask; (6) pattern-transferring onto the organic underlayer film by using the titanium-containing resist underlayer film as a mask; and (7) removing the titanium-containing hard mask and the titanium-containing resist underlayer film by wet stripping method. A patterning process including removing a resist underlayer film using a wet stripper having a milder condition than the conventional stripper without causing damage to a body to be processed.
US08759216B2 Compositions and methods for polishing silicon nitride materials
The present invention provides a method for polishing silicon nitride-containing substrates. The method comprises abrading a surface of a silicon nitride substrate with a polishing composition, which comprises colloidal silica, at least one acidic component, and an aqueous carrier. The at least one acidic component has a pKa in the range of about 1 to 4.5. The composition has a pH in the range of about 0.5 pH units less than the pKa of the at least one acidic component to about 1.5 pH units greater than the pKa.
US08759209B2 Semiconductor device and method of forming a dual UBM structure for lead free bump connections
A semiconductor device has a substrate with a contact pad. A first insulation layer is formed over the substrate and contact pad. A first under bump metallization (UBM) is formed over the first insulating layer and is electrically connected to the contact pad. A second insulation layer is formed over the first UBM. A second UBM is formed over the second insulation layer after the second insulation layer is cured. The second UBM is electrically connected to the first UBM. The second insulation layer is between and separates portions of the first and second UBMs. A photoresist layer with an opening over the contact pad is formed over the second UBM. A conductive bump material is deposited within the opening in the photoresist layer. The photoresist layer is removed and the conductive bump material is reflowed to form a spherical bump.
US08759206B2 Semiconductor device and method for manufacturing the same
A semiconductor device includes a substrate having an insulating surface; a light-transmitting first electrode provided over the substrate; a light-transmitting second electrode provided over the substrate; a light-transmitting semiconductor layer provided so as to be electrically connected to the first electrode and the second electrode; a first wiring electrically connected to the first electrode; an insulating layer provided so as to cover at least the semiconductor layer; a light-transmitting third electrode provided over the insulating layer in a region overlapping with the semiconductor layer; and a second wiring electrically connected to the third electrode.
US08759205B2 Semiconductor device and method for manufacturing semiconductor device
According to one embodiment, a method for manufacturing a semiconductor device, wherein an amorphous semiconductor film comprising a microcrystal is annealed using a microwave, to crystallize the amorphous semiconductor film comprising the microcrystal using the microcrystal as a nucleus.
US08759204B1 Method for manufacturing semiconductor substrate
The inventive concept provides methods for manufacturing a semiconductor substrate. The method may include forming a stop pattern surrounding an edge of a substrate, forming a transition layer an entire top surface of the substrate except the stop pattern, and forming an epitaxial semiconductor layer on the transition layer and the stop pattern. The epitaxial semiconductor layer may not be grown from the stop pattern. That is, the epitaxial semiconductor layer may be isotropically grown from a top surface and a sidewall of the transition layer by a selective isotropic growth method, so that the epitaxial semiconductor layer may gradually cover the stop pattern.
US08759200B2 Methods and apparatus for selective epitaxy of Si-containing materials and substitutionally doped crystalline Si-containing material
The present invention discloses that under modified chemical vapor deposition (mCVD) conditions an epitaxial silicon film may be formed by exposing a substrate contained within a chamber to a relatively high carrier gas flow rate in combination with a relatively low silicon precursor flow rate at a temperature of less than about 550° C. and a pressure in the range of about 10 mTorr-200 Torr. Furthermore, the crystalline Si may be in situ doped to contain relatively high levels of substitutional carbon by carrying out the deposition at a relatively high flow rate using tetrasilane as a silicon source and a carbon-containing gas such as dodecalmethylcyclohexasilane or tetramethyldisilane under modified CVD conditions.
US08759189B2 Reprocessing method of a semiconductor device
A reprocessing method of a semiconductor device, the reprocessing method includes adjusting a resistance value of a first resistor by first trimming the first resistor, wherein the first resistor is electrically connected between a first pad and a second pad, forming a second resistor on the first trimmed first resistor, and adjusting a resistance value of the second resistor by second trimming the second resistor.
US08759188B2 Radiation hardened bipolar injunction transistor
A method for integrating a bipolar injunction transistor in a semiconductor chip includes the steps of forming an intrinsic base region of a second type of conductivity extending in the collector region from a main surface through an intrinsic base window of the sacrificial insulating layer, forming an emitter region of the first type of conductivity extending in the intrinsic base region from the main surface through an emitter window of the sacrificial insulating layer, removing the sacrificial insulating layer, forming an intermediate insulating layer on the main surface, and forming an extrinsic base region of the second type of conductivity extending in the intrinsic base region from the main surface through an extrinsic base window of the intermediate insulating layer.
US08759186B2 Semiconductor device and method for manufacturing the same
A method for manufacturing a semiconductor device includes forming a metal oxide semiconductor layer and a first insulating layer on a substrate. A gate is formed on the first insulating layer. The first insulating layer is patterned by using the gate as an etching mask so as to expose the metal oxide semiconductor layer to serve as a source region and a drain region. A dielectric layer is formed on the substrate to cover the gate and the oxide semiconductor layer, where the dielectric layer has at least one of hydrogen group and hydroxyl group. A heating treatment is performed so that the at least one of hydrogen group and hydroxyl group reacts with the source region and the drain region. A source electrode and a drain electrode electrically connected to the source region and the drain region respectively are formed on the dielectric layer.
US08759185B2 Ultra-shallow junction MOSFET having a high-k gate dielectric and in-situ doped selective epitaxy source/drain extensions and a method of making same
A MOSFET includes a gate having a high-k gate dielectric on a substrate and a gate electrode on the gate dielectric. The gate dielectric protrudes beyond the gate electrode. A deep source and drain having shallow extensions are formed on either side of the gate. The deep source and drain are formed by selective in-situ doped epitaxy or by ion implantation and the extensions are formed by selective, in-situ doped epitaxy. The extensions lie beneath the gate in contact with the gate dielectric. The material of the gate dielectric and the amount of its protrusion beyond the gate electrode are selected so that epitaxial procedures and related procedures do not cause bridging between the gate electrode and the source/drain extensions. Methods of fabricating the MOSFET are described.
US08759182B2 Manufacturing method for semiconductor device
A semiconductor device having an improved negative bias temperature instability lifetime characteristic is manufactured by forming a first insulating layer on a substrate, performing a first nitridation on the first insulating layer to form a second insulating layer, and sequentially performing a first and second anneal on the second insulating layer to form a third insulating layer, wherein the second anneal is performed at a higher temperature and with a different gas than the first anneal. A second nitridation is performed on the third insulating layer to form a fourth insulating layer, and a sequential third and fourth anneal on the fourth insulating layer forms a fifth insulating layer. The third anneal is performed at a higher temperature than the first anneal, and the fourth anneal is performed at a higher temperature than the second anneal and with a different gas than the third anneal.
US08759179B2 Method of forming gate pattern and semiconductor device
This disclosure relates to a method of forming a gate pattern and a semiconductor device. The gate pattern comprises a plurality of parallel gate bars, and each gate bar is broken up by gaps. The method comprises: making an etching characteristic of a gate material layer at least at positions where the gaps are to be formed different from that at remaining positions; forming a plurality of parallel openings in a second resist layer; performing a first etching process on the gate material layer with the second resist layer as a mask, wherein portions of the gate material layer at least at the positions where the gaps are to be formed are selectively left; and performing a second etching process on the gate material layer so as to selectively remove the portions. This method can more accurately control the shape and size of the gate pattern.
US08759178B2 Method for manufacturing semiconductor device and semiconductor device
A manufacturing method includes forming a fin-shaped silicon layer on a silicon substrate, forming a first insulating film around the fin-shaped silicon layer, and forming a pillar-shaped silicon layer on the fin-shaped silicon layer; forming diffusion layers in an upper portion of the pillar-shaped silicon layer, an upper portion of the fin-shaped silicon layer, and a lower portion of the pillar-shaped silicon layer; forming a gate insulating film, a polysilicon gate electrode, and a polysilicon gate wiring; forming a silicide in an upper portion of the diffusion layer in the upper portion of the fin-shaped silicon layer; depositing an interlayer insulating film, exposing the polysilicon gate electrode and the polysilicon gate wiring, etching the polysilicon gate electrode and the polysilicon gate wiring, and then depositing a metal to form a metal gate electrode and a metal gate wiring; and forming a contact.
US08759176B2 Patterning of submicron pillars in a memory array
Methods in accordance with the invention involve patterning and etching very small dimension pillars, such as in formation of a memory array in accordance with the invention. When dimensions of pillars become very small, the photoresist pillars used to pattern them may not have sufficient mechanical strength to survive the photoresist exposure and development process. Using methods according to the present invention, these photoresist pillars are printed and developed larger than their intended final dimension, such that they have increased mechanical strength, then are shrunk to the desired dimension during a preliminary etch performed before the etch of underlying material begins.
US08759173B2 Finlike structures and methods of making same
Semiconductor materials, particularly III-V materials used to form, e.g., a finlike structure can suffer structural damage during chemical mechanical polishing steps. This damage can be reduced or eliminated by oxidizing the damaged surface of the material and then etching away the oxidized material. The etching step can be accomplished simultaneously with a step of etching back a patterned oxide layers, such as a shallow trench isolation layer.
US08759164B2 Method for manufacturing integral imaging device
In a method for manufacturing an integral imaging device, a layer of curable adhesive is first applied on a flexible substrate and half cured such that the curable adhesive is solidified but is capable of deforming under external forces. Then the curable adhesive is printed into a lenticular lens having a predetermined shape and size using a roll-to-roll processing device and fully cured such that the curable adhesive is capable of withstanding external forces to hold the predetermined shape and size. Last, a light emitting diode display is applied on the flexible substrate opposite to the lenticular lens such that an image plane of the light emitting diode display coincides with a focal plane of the lenticular lens.
US08759158B2 Assembly jig for a semiconductor device and assembly method for a semiconductor device
In aspects of the assembly jig and method of the invention, when a packaging substrate is curved concaving upward at temperatures of melting solder, the gap between the assembly jig and the packaging substrate can be made smaller than the dimension of the sum of the thickness of the semiconductor chip and the thickness of the melted solder by allowing a part of the bottom surface of the chip positioning piece to become always, or substantially always, in contact with the upper surface of the packaging substrate owing to the weight of the chip positioning jig itself. As a consequence, the semiconductor chip does not slip aside out of the opening of the chip positioning piece. Therefore, the semiconductor chip can be positioned accurately on the packaging substrate.
US08759155B2 Semiconductor device and method of forming insulating layer disposed over the semiconductor die for stress relief
A semiconductor device has a semiconductor die and conductive layer formed over a surface of the semiconductor die. A first channel can be formed in the semiconductor die. An encapsulant is deposited over the semiconductor die. A second channel can be formed in the encapsulant. A first insulating layer is formed over the semiconductor die and first conductive layer and into the first channel. The first insulating layer extends into the second channel. The first insulating layer has characteristics of tensile strength greater than 150 MPa, elongation between 35-150%, and thickness of 2-30 micrometers. A second insulating layer can be formed over the semiconductor die prior to forming the first insulating layer. An interconnect structure is formed over the semiconductor die and encapsulant. The interconnect structure is electrically connected to the first conductive layer. The first insulating layer provides stress relief during formation of the interconnect structure.
US08759152B2 Configurable interposer
A modularized interposer includes a plurality of interposer units that are assembled to provide a complete set of electrical connections between two semiconductor chips. At least some of the plurality of interposer units can be replaced with other interposer units having an alternate configuration to enable selection of different functional parts of semiconductor chips to be connected through the modularized interposer. Bonding structures, connected to conductive metal pads located at peripheries of neighboring interposer units and an overlying or underlying portion of a semiconductor chip, can provide electrical connections between the neighboring interposer units. The interposer units can be provided by forming through-substrate vias (TSV's) in a substrate, forming patterned conductive structures on the substrate, and cutting the substrate into interposers.
US08759151B2 Fixture to constrain laminate and method of assembly
A fixture assembly and method of forming a chip assembly is provided. The fixture assembly includes a first plate having an opening sized to accommodate a chip mounted on a laminate. The fixture assembly further includes a second plate mated to the first plate by at least one mechanical fastening mechanism. The fixture assembly further includes a space defined by facing surfaces of the first plate and the second plate and confined by a raised stepped portion of at least one of the first plate and the second plate. The space is coincident with the opening. The space is sized and shaped such that the laminate is confined within the space and directly abuts the stepped portion and the facing surfaces of the first plate and the second plate to be confined in X, Y and Z directions.
US08759145B2 Organic light emitting diode display and manufacturing method thereof
An organic light emitting diode display comprises: a display panel; a touch screen panel disposed on a display surface of the display panel; a sensing unit for sensing a position through the touch screen panel; and a polarizing plate disposed on the touch screen panel, wherein the touch screen panel is attached to the display surface area of the display panel with an air layer provided therebetween.
US08759142B2 Method for producing thin-film light-absorbing layer and method for manufacturing thin-film solar cell including the same
Disclosed is a method for producing a copper indium selenium (CIS) or copper indium gallium selenium (CIGS) thin-film light-absorbing layer. The method includes forming a coating layer of CIGS slurry, removing a solvent, a dispersant and a binder from the coating layer to form a powder coat layer, pressing the powder coat layer to improve its particle packing density, and heating the powder layer to form a dense thin film. The method uses a powder process as a non-vacuum process to produce a CIS or CIGS thin film in high yield at low cost. Further disclosed is a method for manufacturing a thin-film solar cell including the production method.
US08759138B2 Concentrated photovoltaic system modules using III-V semiconductor solar cells
A solar cell receiver for use in a concentrating solar system which concentrates the solar energy onto a solar cell for converting solar energy to electricity. The solar cell receiver may include a solar cell mounted on a support and with one or more III-V compound semiconductor layers. An optical element may be positioned over the solar cell and have an optical channel with an inlet that faces away from the solar cell and an outlet that faces towards the solar cell. A frame may be positioned over the support and extend around the solar cell with the frame having an inner side that extends above the support and faces towards the optical element. An encapsulant may be positioned over the support and contained between the optical element and the frame. The encapsulant may have enlarged heights at contact points with the optical element and the frame and a reduced height between the contact points away from the optical element and the frame. The solar cell receiver may be used in a solar cell module.
US08759133B2 Back panel for flat panel display apparatus, flat panel display apparatus comprising the same, and method of manufacturing the back panel
A back panel for a flat panel display apparatus includes: a pixel electrode disposed on a substrate; a first gate electrode layer of a thin-film transistor (TFT) disposed on the substrate; a second gate electrode layer disposed on the first gate electrode layer and including a semiconductor material; a third gate electrode layer disposed on the second gate electrode layer and including a metal material; a first insulating layer disposed on the third gate electrode layer; an active layer disposed on the first insulating layer and including a transparent conductive oxide semiconductor; a second insulating layer disposed on the active layer; source and drain electrodes disposed connected to the active layer through the second insulating layer; and a third insulating layer covering the source and drain electrodes. The first gate electrode layer and the pixel electrode include a transparent conductive oxide.
US08759127B2 Gold micromask for roughening to promote light extraction in an LED
Gold is used as a micromask to roughen a gallium nitride (GaN) surface in an LED device. In one example, a mesh of ITO (Indium Tin Oxide) is formed on a GaN layer. The mesh has holes that extend down to the GaN. A layer of silicon dioxide is deposited so that it covers the GaN at the bottoms of the holes. A layer of gold is formed over the oxide. A thermal treatment causes the gold to ball up into small gold features. These gold features are used as a micromask in a subsequent etching step. Areas of the bottoms of the holes that are not covered by a gold feature are etched. Etching occurs through the oxide and down into the GaN. The roughening process involves no silver, and involves no harsh cleaning solvents or processes that might otherwise have been used were the micromask made of silver.
US08759125B2 Light-emitting dies incorporating wavelength-conversion materials and related methods
In accordance with certain embodiments, semiconductor dies are embedded within polymeric binder to form, e.g., freestanding white light-emitting dies and/or composite wafers containing multiple light-emitting dies embedded in a single volume of binder.
US08759123B2 Method of manufacturing LED lamp
A method of manufacturing a LED lamp that is formed by sealing a LED element mounted on a substrate with glass, includes a mounting process for mounting the LED element on the substrate, a sealing member preparation process for preparing a glass sealing member that includes a concave portion being capable of housing the LED element, and a sealing process wherein the sealing member is arranged so that a forming surface of the concave portion faces the LED element, the sealing member is bonded to the substrate by thermal compression bonding, and the forming surface of the concave portion is made along the LED element.
US08759121B2 Light emitting diode array and method for manufacturing the same
An LED array includes a substrate and a plurality of LEDs formed on the substrate. The LEDs are electrically connected with each other. Each of the LEDs includes a connecting layer, an n-type GaN layer, an active layer, and a p-type GaN layer formed on the substrate in sequence. The connecting layer is etchable by alkaline solution. A bottom surface of the n-type GaN layer which connects the connecting layer has a roughened exposed portion. The bottom surface of the n-type GaN layer has an N-face polarity. A method for manufacturing the LED array is also provided.
US08759118B2 Plating process and structure
A system and method for plating a contact is provided. An embodiment comprises forming protective layers over a contact and a test pad, and then selectively removing the protective layer over the contact without removing the protective layer over the test pad. With the protective layer still on the test pad, a conductive layer may be plated onto the contact without plating it onto the test pad. After the contact has been plated, the protective layer over the contact may be removed.
US08759116B2 Identification of objects using plasmon resonant particles
A method and apparatus for identifying an object having a pattern of plasmon resonant particles (PREs) distributed in or on the object are disclosed. In the method, a field containing the pattern is illuminated, and one or more spectral emission characteristics of the light-scattering particles in the field are detected. From this data, an image of positions and spectral characteristic values in the field is constructed, allowing PREs with a selected spectral signature to be discriminated from other light-scattering entities, to provide information about the field. The image may be compared to a database of reference images to identify or validate the object.
US08759111B2 Nanoporous detectors of monocyclic aromatic compounds and other pollutants
Porous sol-gel material essentially consisting of units of one or more first polyalkoxysilanes chosen from the following compounds: (chloromethyl)triethoxysilane; 1,3-dimethyltetramethoxydisiloxane; ethyl trimethoxysilane; triethoxy(ethyl)silane; triethoxymethylsilane; triethoxy(vinyl)silane; trimethoxymethylsilane; trimethoxy(vinyl)silane; tetraethoxysilane or tetramethoxysilane (TMOS) and of units of one or more second polyalkoxysilanes chosen from the following compounds: (N-(3-(trimethoxysilyl)propyl)ethylenediamine; 3-aminopropyltriethoxysilane (APTES) and 3-aminopropyltrimethoxysilane, in a first polyalkoxysilane/second polyalkoxysilane molar ratio of 1/0.01 to 1/1, optionally comprising a probe molecule, method of preparation and applications in the trapping of monocyclic aromatic hydrocarbons and other pollutants or in their detection.
US08759110B2 Metal enhanced fluorescence-based sensing methods
The present invention relates to metallic-surface detection systems for determining target substances including free bilirubin in neonatal serum in the presence of a predominantly high background of bilirubin bound Human Serum Albumin (HSA) or sensing and isolating target nucleotide sequences wherein a fluorescence signal is enhanced by close proximity of the target substances near metallic surfaces.
US08759108B2 Reagent kit for detecting lupus anticoagulant and method of determining presence or absence of lupus anticoagulant
In order to provide a reagent kit for detecting LA which can clearly separate a lupus anticoagulant (LA)-positive specimen group from an LA-negative specimen group, it is configured that the reagent kit for detecting LA contains a first clotting time-measuring reagent and a second clotting time-measuring reagent and at least one of the first clotting time-measuring reagent and the second clotting time-measuring reagent contains alkali metal salt. The presence or absence of LA can be determined using the kit.
US08759107B2 Titanium bearing material flow control in the manufacture of titanium tetrachloride using a combination of feedback and feed forward responses
This disclosure relates to process for controlling chlorination reactions in manufacturing titanium tetrachloride in a fluidized bed reactor, optionally followed by processing to form a titanium product comprising a minor amount of silica, the process comprising: (a) feeding carbonaceous material, titanium bearing material comprising an amount of silica, and chlorine to the fluidized bed reactor to form a gaseous stream, and condensing the gaseous stream to form titanium tetra-chloride, a non-condensed gas stream and a condensable product stream, wherein at least one of the titanium tetrachloride and the non-condensed gas stream comprise silicon tetrachloride; (b) analyzing the non-condensed gas stream, the titanium tetrachloride or both, to determine the analyzed concentration of silicon tetrachloride; (c) identifying a set point concentration of silicon tetrachloride based on the desired amount of silica in the titanium product; (d) calculating the difference between the analyzed concentration of silicon tetra-chloride and the set point concentration of silicon tetrachloride; (e) measuring the titanium tetrachloride flow to a processing reactor that releases chlorine; (f) measuring the flow of fresh chlorine added to the fluidized bed; (g) measuring the flow of the titanium bearing material added to the fluidized bed reactor and establishing a historic average flow of the titanium bearing material added to the fluidized bed reactor; (h) calculating the chlorine released from the titanium tetrachloride that is processed using the titanium tetrachloride flow data from step (e); (i) calculating the total chlorine flow to the fluidized bed reactor by adding the chlorine flow in step (f) to the chlorine flow calculated in step (h) and establishing a historic average chlorine flow; (j) calculating a unit titanium bearing material consumption per unit chlorine; (k) calculating an estimated current consumption rate of titanium bearing material based on the total chlorine flow from step (i) times the unit titanium bearing material consumption per unit chlorine from step (j); and (l) generating a signal based on difference generated in step (d) that provides a feedback response and combining this to the estimated current consumption rate of titanium bearing material from step (k) to provide a feed forward response to control the flow of the titanium bearing material into the fluidized bed reactor.
US08759095B2 Diagnostic and therapeutic tools for diseases altering vascular function
The invention relates to diagnostic and therapeutic tools and applications, particularly useful in diseases that affect vascular health and in inflammatory diseases. In particular, said diagnostic and therapeutic tools employ suitable detection or modulation of endothelial glycocalyx.
US08759094B2 Hematocrit and analyte concentration determination
A method to determine an analyte concentration of an anticoagulated plasma by performing at least two different measurements on a mixture of a blood sample corresponding to said anticoagulant plasma and of liquid reagent is described. The method comprises a) mixing a volume of said blood sample with a five-fold, or more, volume of said liquid reagent, b) performing said at least two measurements on said mixture, at least one of which correlates with the hematocrit of said blood sample and at least one of which correlates with said analyte concentration, and c) computing the results from the measurements when the volumes in a) are precise and accurate or when the hematocrit of said blood sample in b) is known to determine said analyte concentration of said anticoagulated plasma. In addition, a measurement and determination device for performing measurements on blood, anticoagulated blood and/or anticoagulated plasma samples, and an equipment kit are described.
US08759093B2 Method for determining the selectivity of a pre-synaptic neuromuscular blocking substance
The present invention relates to a method for determining the selectivity of a pre-synaptic neuromuscular blocking substance for striated muscle or smooth muscle. The method comprises measuring the effect induced by a pre-determined quantity of pre-synaptic neuromuscular blocking substance upon electrically stimulating striated muscle tissue, measuring the effect induced by a pre-determined quantity of a pre-synaptic neuromuscular blocking substance upon electrically stimulating smooth muscle tissue, and calculating a quotient of the results obtained in order to determine the selectivity of the pre-synaptic neuromuscular blocking substance for striated muscle or for smooth muscle.
US08759092B2 Preparation of vaccines using photosensitizer and light
Methods are provided for treating a vaccine containing infectious particles which may be viral, bacterial, and/or cellular in nature. Preferred methods include the steps of adding an effective, non-toxic amount of an endogenous photosensitizer to the fluid and exposing the fluid to photoradiation sufficient to inactivate the infectious particles but not enough to damage the antigenic characteristics of the infectious particles.
US08759085B2 Temperature control device with a flexible temperature control surface
A device for controlling temperature in a reaction chamber is disclosed. The device comprises: a bladder assembly comprising a housing dimensioned to hold a reaction chamber disposed within an interior volume of the housing; and a first temperature-control bladder disposed within the housing, the first temperature-control bladder is configured to receive a temperature-control fluid and comprises a flexible, heat conductive surface that comes in contact with at least a portion of an exterior surface of the reaction chamber after receiving the temperature-control fluid. Also disclosed are a bladder thermal cycler, a temperature-control bladder assembly and methods for producing a thermal cycle in a reaction chamber.
US08759084B2 Self-sterilizing automated incubator
A method and system for self-sterilizing an automated incubator is disclosed. The internal temperature of the automated incubator is elevated by forcing hot air to flow into the internal incubation chamber, wherein all mechanics and electronics associated with the automated plate mover are outside the internal incubation chamber. During sterilization, the heating system of the automated incubator will force hot air to flow over the internal surfaces of the incubator, thereby reducing contaminating microorganism resistance by inducing dehydration.
US08759075B2 Biologic sample collection devices and methods of production and use thereof
Collection devices and kits for biological sample collection include a biologic sample collection device having a hydrophilic swab matrix that includes a modified polycaprolactone (PCL). Methods of production and use thereof are also described herein. The biologic sample collection devices, kits and methods described herein are used to collect a biologic sample (e.g., blood, buccal cells, etc.) and to enable extraction of nucleic acids (e.g., DNA) from that biologic sample so that the nucleic acids can be analyzed (e.g., sequencing and subsequent analysis of DNA).
US08759072B2 Protein exhibiting activity of pyrethrin biosynthetic enzyme, gene encoding the protein, and vector bearing the gene
The present invention relates to an enzyme determining amino acid sequences of an enzyme involved in pyrethrin biosynthesis and a base sequence of the gene thereof; constructing vectors bearing the gene and transformants; and extractable from plant bodies producing pyrethrin by applying such creative techniques to plant bodies with faster growth aiming to provide a method to efficiently produce pyrethrin; and the enzyme is a gene encoding a protein of the following (i) or (ii) or (iii): (i) a protein consisting of an amino acid sequence shown in Sequence No. 1; or (ii) a protein consisting of an amino acid sequence shown in Sequence No. 5, or a protein consisting of an amino acid sequence shown in Sequence No. 6, or a protein consisting of an amino acid sequence shown in Sequence No. 7, or a protein consisting of an amino acid sequence shown in Sequence No. 8, (iii) a protein consisting of an amino acid sequence including one or more of a substitution, deletion, insertion, and/or addition of amino acid in the amino acid sequence shown in Sequence No. 1, in which the protein exhibits activity of pyrethrin biosynthetic enzyme.
US08759066B2 Thrombin activator compositions and methods of making and using the same
Disclosed are compositions for activating thrombin precursors to thrombin. The compositions provided include polypeptide compositions wherein the pre-pro-sequence comprises a thrombin cleavage site. The compositions provided also include polynucleotides encoding said polypeptides and recombinant systems for expressing said polypeptides. This disclosure also relates to methods for producing said compositions, recovering said compositions, activating said compositions purifying said compositions and producing active thrombin molecules using the active form of said compositions.
US08759064B2 Cellobiohydrolase variants
The invention relates to recombinant expression of variant forms of C1 CBH1a and homologs thereof, having improved thermostability, low-pH tolerance, specific activity and other desirable properties. Also provided are methods for producing ethanol and other valuable organic compounds by combining cellobiohydrolase variants with cellulosic materials.
US08759063B2 DNA polymerases with improved activity
Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
US08759060B2 PEG-modified arginine/lysine oxidoreductase
The present invention is directed to an arginine/lysine oxidoreductase modified with polyethylene glycol, a production method thereof, and methods of treating disorders responsive to a modification of amino acid levels reactive oxygen species and/or ammonium.
US08759059B2 3-hydroxypropionic acid and other organic compounds
Methods and materials related to producing 3-HP as well as other organic compounds are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, and methods and materials for producing 3-HP and other organic compounds are disclosed.
US08759057B1 Methods for purifying enzymes for mycoremediation
A process for purifying laccase from an ectomycorrhizal fruiting body is disclosed. The process includes steps of homogenization, sonication, centrifugation, filtration, affinity chromatography, ion exchange chromatography, and gel filtration. Purified laccase can also be separated into isomers.
US08759056B2 Method for producing granules containing fungi of the moniliales family
A process for the production of granules or pellets containing filamentous fungi is described comprising the steps of selecting and growing filamentous fungi in a suitable culture medium for a predetermined amount of time, adding a gelling agent and at least one carrier to said culture medium, so as to obtain a mixture, subjecting said mixture to gelling through contact, drop by drop, with a solution containing a calcium salt thus obtaining gelled pellets or granules containing said filamentous fungi and drying said gelled pellets or granules to a moisture content of 13-18%.
US08759052B2 Process for producing biogas
Process for the production of a biogas containing methane from an organic matter amenable to anaerobic digestion comprising feeding an anaerobic digester with the organic matter, said anaerobic digester containing a digestion medium comprising microorganisms capable of digesting said organic matter, wherein the total inorganic carbon concentration of the digestion medium is maintained above 9000 mg of equivalent CaCO3/l and the buffering capacity is maintained above 200 mmol/l by the addition of a buffering reagent comprising sodium bicarbonate to the digestion medium.
US08759050B2 Process and system for producing ethanol from a byproduct of an ethanol production facility
A process of producing ethanol from whole stillage, includes obtaining a supply of whole stillage from an ethanol production facility after ethanol has been extracted therefrom; pre-treating the whole stillage to convert hemicellulose portions of the whole stillage into sugars; adding enzymes to the whole stillage to convert cellulose portions of the whole stillage to sugars; fermenting the whole stillage to create a beer mixture; and distilling the beer mixture to separate ethanol therefrom. The pre-treating step may include adding acid to the whole stillage to decrease its pH level; heating and pressurizing the whole stillage; holding the whole stillage under pressure and heat for a dwell time; removing pressure from the whole stillage to cause flashing; and cooling the whole stillage before the enzymes are added.
US08759049B2 Method for the production of a fermentation product from a sugar hydrolysate
The present invention relates to a method for producing a fermentation product from a sugar hydrolysate. The method comprises fermenting the sugar hydrolysate in a fermentation system with yeast to produce a fermentation broth comprising a fermentation product; introducing acid and an oxidant, such as chlorine dioxide, to the fermentation system so as to expose microbial contaminants in the fermentation system at one or more stages to chlorine dioxide and a pH of less than 3.0; and recovering the fermentation product. In one example of the invention, a yeast slurry obtained from a yeast recycle step is treated with acid and the oxidant.
US08759048B2 Method and system for collecting ethanol from aquatic plants
Methods and systems for collecting, purifying, and/or extracting ethanol produced during anaerobic metabolism by aquatic plants is provided. The system includes a cell containing water and an aquatic plant, an ethanol extraction assembly in fluid communication with the cell for removing ethanol from the water. Ethanol is released by the aquatic plant by initiating an anaerobic process in the plant such as by regulating the photosynthesis inducing light that reaches the aquatic plant.
US08759046B2 Process for producing prenyl alcohols
A method of producing a prenyl alcohol(s) by culturing a mutant cell into which a fusion gene of farnesyl diphosphate synthase gene and geranylgeranyl diphosphate synthase gene has been introduced and recovering the prenyl alcohol(s) from the resultant culture.
US08759045B2 Lactic acid production method
A method of producing lactic acid by separating lactic acid produced in a culture solution by microbial fermentation, comprising: a step (A) of filtering the culture solution through a nano-filtration membrane; and a step (B) of distilling a lactic-acid-containing solution produced in step (A) under a pressure of 1 Pa to atmospheric pressure (inclusive) at a temperature of 25 to 200° C. (inclusive) to recover lactic acid.
US08759042B2 Method for production of amino acid
The invention provides a microorganism belonging to Enterobacteriaceae in which a function of CsrC RNA has been decreased or lost, and which has the ability to produce and accumulate an amino acid, and a process in which the microorganism is cultured in a medium to produce and accumulate the amino acid in the culture, and the amino acid is recovered from the culture.
US08759040B1 Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having cellobiohydrolase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
US08759036B2 Methods for synthesizing pools of probes
Compositions, methods and kits are disclosed for synthesizing and amplifying pools of probes using precursor oligonucleotides. In some aspects the precursor is amplified and nicking enzymes are used to separate the full length probes from the amplification products. The methods enable the preparation of single stranded DNA probes of defined sequence and length that are suitable for use in target detection assays.
US08759035B2 Methods for determination of haplotype dissection
A method for molecular haplotyping of a subject is disclosed. The method comprises: randomly selecting a set of chromosomes in each of a plurality of lyzed diploid cells of the subject, collecting the selected chromosomes from said plurality of cells into a plurality of sample tubes, wherein each sample tube contains chromosomes selected from one or more cells, genotyping genomic DNA in each sample tube, and determining haplotype of the alleles based on allele nucleotide sequence information and corresponding nucleotide signal intensities from genotyping data. Other methods for molecular haplotyping using single cell lysate or single cell microdissection are also disclosed.
US08759034B2 Thermostable biocatalyst combination for nucleoside synthesis
A recombinant expression vector comprising: a) the sequence encoding a purine nucleoside phosphorylase (PNPase, E. C. 2.4.2.1), b) the sequence encoding a uridine phosphorylase (UPase, E. C. 2.4.2.3), c) or both; each of the sequences operably linked to one or more control sequences that direct the production of said phosphorylases in a suitable expression host; said sequences originating from the Archaea Thermoprotei class, characterized in that the PNPase is from Sulfolobus solfataricus (SEQ ID NO. 7) and the UPase is from Aeropyrum pernix (SEQ ID NO. 8). In addition, the present invention relates to A transglycosylation method between a sugar-donating nucleoside and an acceptor base in the presence of phosphate ions, characterized in that said method comprises the use of a uridine phosphorylase (UPase) of Aeropyrum pernix (NC_000854.2), a purine nucleoside phosphorylase (PNpase) of Sulfolobus solfataricus (NC_002754.1), or a combination thereof.
US08759031B2 Type I polyketide synthase extender units
Novel extender units for Type I polyketide synthases are provided. Also provided are genes, compounds, and methods for generating these units, and for incorporation of the novel extender units into polyketides for the purpose of generating new structural derivatives of polyketide-containing products.
US08759029B2 Antibodies and their use in the treatment, prevention and diagnosis of a disease associated with SOD1 abnormalities
The present invention concerns an antibody which specifically binds to an abnormal superoxide dismutase 1 (SOD1), and which neutralizes its pathologic effect when administered to an animal such as a human. The antibody of the invention is a monoclonal antibody produced by hybridoma cell lines deposited with the International Depositary Authority of Canada on Aug. 29, 2006 under accession numbers ADI-290806-01, ADI-290806-02 and ADI-290806-03. The present invention also concerns the use of the antibody of the invention in the treatment, prevention and diagnosis of neurodegenerative diseases such as Amyotrophic lateral sclerosis, Parkinson and Alzheimer in an animal such as a human.
US08759023B2 Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having cellobiohydrolase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
US08759022B2 Method for selecting mevalonate synthesis modulators using cells derived from human pluripotent cells
The invention provides a method for selecting pharmaceutical compounds affecting mevalonate or cholesterol. The method having a step for putting into contact with the pharmaceutical compounds to be tested, cells of the MSC type obtained by a method for producing cells of the MSC type from human pluripotent cells or from induced stem cells, including a step for cultivating human pluripotent cells or induced stem cells in a culture medium of: 1) one or more growth factors selected from FGFs, HGF, PDGFs, EGF, herugulins and VEGFs; and 2) one or more antioxidants selected from ascorbic acid and its derivatives, vitamin E and N-acetylcysteine.
US08759021B2 Microorganism for quantifying homocysteine, and use thereof
Provided are a microorganism for use in quantification of homocysteine and methionine and a method of quantifying homocysteine and methionine in a sample by using the microorganism.
US08759020B2 Methods for natural product optimization
Methods and compositions for natural product optimization are provided. In particular, methods and compositions for selecting bacterial strains (e.g., predatory bacteria such as myxobacteria) which produce a desired compound (e.g., antibiotic, antifungal, or anticancer agent) are provided.
US08759015B2 Methods of screening T1R1/T1R3 receptors for compounds that modulate umami taste signaling
The present invention relates to the discovery that the T1R receptors assemble to form functional taste receptors. Particularly, it has been discovered that co-expression of T1R1 and T1R3 results in a taste receptor that responds to umami taste stimuli, including monosodium glutamate. Also, it has been discovered that co-expression of the T1R2 and T1R3 receptors results in a taste receptor that responds to sweet taste stimuli including naturally occurring and artificial sweeteners. Finally, the invention relates to the discovery that some compounds, e.g., lactisole, inhibit both the activities of human T1R2/T1R3 and T1R1/T1R3 receptors, and accordingly the sweet and umami taste, suggesting that these receptors may be the only sweet and umami receptors.
US08759010B2 Host cell kinases as targets for antiviral therapies against HCV infection
The present invention provides several networks of cellular protein kinases as potential targets for medical intervention against hepatitis C virus (HCV) infection and HCV-related diseases and disorders in mammals, including humans. The invention relates to therapeutic protocols and pharmaceutical compositions designed to inhibit the activity of one or more of these protein kinases for the prevention and/or treatment of infections and diseases caused by HCV. The invention also relates to methods for the identification of kinase inhibitors that may be used to treat and/or prevent HCV infections and HCV-related diseases.
US08759008B2 Robust, self-assembled, biocompatible films
The present invention provides a composite material including a substrate having an oxide surface, and, a continuous monolayer on the oxide surface, the monolayer including a silicon atom from a trifunctional alkyl/alkenyl/alkynyl silane group that attaches to the oxide surface, an alkyl/alkenyl/alkynyl portion of at least three carbon atoms, a polyalkylene glycol spacer group, and either a reactive site (e.g., a recognition ligand) or a site resistant to non-specific binding (e.g., a methoxy or the like) at the terminus of each modified SAM. The present invention further provides a sensor element, a sensor array and a method of sensing, each employing the composite material. Patterning is also provided together with backfilling to minimize non-specific binding.
US08759001B2 Method for diagnosing renal diseases or predispositions
The invention provides a method of diagnosing a disease or a predisposition to contract a disease by assaying for mutations of uromodulin (UMOD) within a test subject or patient. The presence of a mutation in the UMOD supports a diagnosis of a disease or a predisposition to contract a disease within the patient.
US08758999B2 Methods and compositions for the detection and identification of archaea based on the type II chaperonin (thermosome) gene
The present invention relates to primers for the universal amplification and detection of Archaea, which primers are designed based on a multiple sequence alignment of Archaea Type II chaperonin (thermo-some) genes. For detection of Archaea having templates with a GC content of below 60%, primers are designed so that inosine residues are found at degenerate positions. For amplification of higher GC content templates, degenerate positions are replaced with specific nucleotide bases found in the high GC organism. The primers are useful for detecting, identifying and quantifying Archaea in a sample and for determining a phylogenetic relationship of a test Archaea organism.
US08758996B2 Optimized probes and primers and methods of using same for the binding, detection, differentiation, isolation and sequencing of influenza A; influenza B; novel influenza A/H1N1; and a novel influenza A/H1N1 RNA sequence mutation associated with oseltamivir resistance
Described herein are primers and probes useful for the binding, detecting, differentiating, isolating, and sequencing of influenza A, influenza B, 2009 influenza A/H1N1, and a 2009 influenza A/H1N1 RNA sequence mutation associated with oseltamivir resistance.
US08758995B2 Solid phase sequencing of biopolymers
This invention relates to methods for detecting and sequencing target nucleic acid sequences, to mass modified nucleic acid probes and arrays of probes useful in these methods, and to kits and systems which contain these probes. Useful methods involve hybridizing the nucleic acids or nucleic acids which represent complementary or homologous sequences of the target to an array of nucleic acid probes. These probes comprise a single-stranded portion, an optional double-stranded portion and a variable sequence within the single-stranded portion. The molecular weights of the hybridized nucleic acids of the set can be determined by mass spectroscopy, and the sequence of the target determined from the molecular weights of the fragments. Probes may be affixed to a solid support such as a hybridization chip to facilitate automated molecular weight analysis and identification of the target sequence.
US08758993B2 Systems and methods for predicting response to anti-androgen therapy for the treatment of androgenetic alopecia
Methods, processes, systems, and apparatuses are disclosed for predicting anti-androgen therapy response in the treatment of androgenetic alopecia based on a fluorometric assay and proteomics.
US08758988B2 Cryopreservation of articular cartilage
The invention relates generally to methods and compositions for the cryopreservation and/or vitrification of tissue including articular cartilage and the preparation of said tissue for clinical or research use, including but not limited to joint replacement and the treatment and prevention of osteoarthritis.
US08758985B2 Method of fabricating nanostructure array and device including nanostructure array
Provided are a method of fabricating a nanostructure array and a device including the nanostructure array. Nanoscale patterning is caused at an interface of a resist layer by light passed through a focusing layer. By such nanoscale patterning, a nanostructure array is fabricated on a substrate in various ways. As the focusing layer, an array of beads or lenses is used, and a pattern of the resist layer may include a nanoscale pore-opening and an undercut structure connected to a lower portion of the opening. The method facilitates adjustment of the size and shape of nanostructures and the interval between the nanostructures. Also, performance of the device including the nanostructure array can be improved. In particular, the method and device result in a sensor having improved sensitivity and reliability optimized for an environment and purpose to be used.
US08758979B2 Photoresist composition
Methanofullerene derivatives having side chains with acid-labile protecting groups. The methanofullerene derivatives may find application as photoresist materials, and particularly as positive-tone photoresists.
US08758977B2 Negative-type photosensitive resin composition, pattern forming method and electronic parts
A negative-type photosensitive resin composition which is good in sensitivity and resolution, a pattern forming method by the use thereof wherein a pattern which can be developed in an alkali aqueous solution, is excellent in sensitivity, resolution and heat resistance and has a good shape is obtained, and highly reliable electronic parts are provided. The negative-type photosensitive rein composition includes (a) a polymer that has a phenolic hydroxyl group at a terminal and is soluble in the alkali aqueous solution, (b) a compound that generates an acid by irradiating active light, and (c) a compound that can be crosslinked or polymerized by an action of the acid.
US08758976B2 Positive photosensitive polyimide composition
The present invention relates to a positive photosensitive polyimide composition that includes polyimide, a polyamic acid, and a photoactive compound. An organic insulating layer for organic light-emitting devices (OLED), which includes the positive photosensitive polyimide composition, may control a taper angle and outgassing, and has excellent adhesion in respects to a substrate, water repellent control ability, and storage stability and the like.
US08758975B2 Lithographic printing plate precursor and method of preparing lithographic printing plate
A lithographic printing plate precursor includes a support and one or more layers, one of the one or more layers is a photosensitive layer containing an initiator compound, a polymerizable compound and a binder polymer, and a layer being in contact with the support of the one or more layers contains a copolymer containing a repeating unit having a zwitterionic structure and a repeating unit having a structure capable of interacting with a surface of the support.
US08758971B2 Image-forming method
An image-forming method uses an electrophotographic photosensitive member having a surface layer formed of a hydrogenated amorphous silicon carbide in which a ratio of the number of carbon atoms to the sum of the number of silicon atoms and the number of the carbon atoms in the surface layer is 0.61 or more and 0.75 or less, and the sum of the atomic density of the silicon atoms and the atomic density of the carbon atoms in the surface layer is 6.60×1022 atoms/cm3 or more, and the peak wavelength of pre-exposure light is shorter than the peak wavelength of image exposure light.
US08758970B2 Deinking a print
A method of deinking an image-bearing member using an organic solvent includes receiving the image-bearing member. The member has thereon a continuous or discontinuous image layer formed of toner particles that do not include colorant, and colorant particles or molecules. The colorant particles or molecules are arranged in a pattern corresponding to the arrangement of the toner particles. The organic solvent is hydrophobic or oliophilic and the colorant is insoluble in the organic solvent. The hydrophobic or oliophilic organic solvent is applied to the image-bearing member, so that a majority of the toner image layer is dissolved off the image-bearing member and the colorant is removed from the image-bearing member. A deinked reflection density of the image-bearing member in a selected test area from which the toner image layer was dissolved is within 0.15 of an unprinted reflection density of the image-bearing member before deinking.
US08758963B2 Holographic reticle and patterning method
A hologram reticle and method of patterning a target. A layout pattern for an image to be transferred to a target is converted into a holographic representation of the image. A hologram reticle is manufactured that includes the holographic representation. The hologram reticle is then used to pattern the target. Three-dimensional patterns may be formed in a photoresist layer of the target in a single patterning step. These three-dimensional patterns may be filled to form three-dimensional structures or else used in a multi-surface imaging composition. The holographic representation of the image may also be transferred to a top photoresist layer of a top surface imaging (TSI) semiconductor device, either directly or using the hologram reticle. The top photoresist layer may then be used to pattern an underlying photoresist layer with the image. The lower photoresist layer is used to pattern a material layer of the device.
US08758962B2 Method and apparatus for sub-pellicle defect reduction on photomasks
In one embodiment, the invention is a method and apparatus for sub-pellicle defect reduction on photomasks. One embodiment of a photomask for use in photolithography includes a substrate on which a pattern is formed, the substrate having a frontside and an opposite backside, and a protective coating formed on at least one of the frontside and the backside, the protective coating comprising silicon-based compound.
US08758958B2 Fuel cell separator plate assembly
A fuel cell separator plate assembly (20) includes a separator plate layer (22) and flow field layers (24, 26). In one disclosed example, the separator plate layer (22) comprises graphite and a hydrophobic resin. The hydrophobic resin of the separator plate layer (22) serves to secure the separator plate layer to flow field layers on opposite sides of the separator plate layer. In one example, at least one of the flow field layers (24, 26) comprises graphite and a hydrophobic resin such that the flow field layer is hydrophobic and nonporous. In another example, two graphite and hydrophobic resin flow field layers are used on opposite sides of a separator plate layer. One disclosed example includes all three layers comprising graphite and a hydrophobic resin.
US08758957B2 Graphene coated SS bipolar plates
A flow field plate for fuel cell applications includes a metal with a graphene-containing layer disposed over at least a portion of the metal plate. The graphene-containing layer includes an activated surface which is hydrophilic. Moreover, the flow field plate is included in a fuel cell with a minimal increase in contact resistance. Methods for forming the flow field plates are also provided.
US08758955B2 Additives to mitigate catalyst layer degradation in fuel cells
Ligand additives having two or more coordination sites in close proximity can be used in the polymer electrolyte of membrane electrode assemblies in solid polymer electrolyte fuel cells in order to reduce the dissolution of catalyst, particularly from the cathode, and hence reduce fuel cell degradation over time.
US08758951B2 Electrocatalysts and additives for the oxidation of solid fuels
A continuous coal electrolytic cell for the production of pure hydrogen without the need of separated purification units Electrodes comprising electrocatalysts comprising noble metals electrodeposited on carbon substrates are also provided. Also provided are methods of using the electrocatalysts provided herein for the electrolysis of coal in acidic medium, as well as electrolytic cells for the production of hydrogen from coal slurries in acidic media employing the electrodes described herein. Further provided are catalytic additives for the electro-oxidation of coal. Additionally provided is an electrochemical treatment process where iron-contaminated effluents are purified in the presence of coal slurries using the developed catalyst.
US08758950B2 Fuel cell system
A fuel cell system includes a reforming unit, a carbon monoxide decreasing unit, a fuel cell, a burner unit, a raw gas supply device, and a heating unit. The heating unit is controlled at a start-up operation of the fuel cell system, so as to adjust an amount of a desorbed raw gas desorbed out of components of the raw gas adsorbed to at least one of a reforming catalyst and a carbon monoxide decreasing catalyst such that a ratio of an amount of combustion air to an amount of a raw gas in the burner unit falls within a predetermined range.
US08758945B2 Overcharge protection by coupling redox shuttle chemistry with radical polymerization additives
The over charge protection of a lithium ion cell is improved by using an electrolyte comprising at least one redox shuttle additive that comprises an in situ generated soluble oxidizer or oxidant to accelerate other forms of chemical overcharge protection. The oxidizer can be employed in combination with radical polymerization additives.
US08758944B2 Lithium secondary battery containing additive for improved high-temperature characteristics
Provided is a secondary battery containing polyalkyleneglycol diglycidylether represented by formula I added in a predetermined amount to an electrolyte for the battery. The secondary battery containing the above additive exhibits remarkably improved high-temperature characteristics, prevents deterioration in rate characteristics and cycle characteristics, and considerably reduces thickness swelling of the battery so as to prevent battery leakage, ultimately enhancing safety of the battery.
US08758941B2 Positive electrode material for lithium ion secondary battery and lithium ion secondary battery using the same
This invention provides a positive electrode material having high capacity and safety, and a lithium ion secondary battery using the positive electrode material, the lithium ion secondary battery using a positive electrode active substance comprising a first transition metal oxide represented by the compositional formula: Lix1Nia1Mnb1Coc1Md1O2; a second transition metal oxide represented by the compositional formula: Lix2Nia2Mnb2Coc2Md2O2; and a third transition metal oxide represented by the compositional formula: Lix3Nia3Mnb3Coc3Md3O2; in which a3
US08758940B2 Lithium-titanium complex oxide, and battery electrode and lithium ion secondary battery using same
A lithium-titanium complex oxide containing Li4Ti5O12 is characterized in that, based on SEM observation, the number-based percentage of particles whose size is less than 0.1 μm is 5 to 15% or 40 to 65%, the number-based percentage of particles whose size is 0.3 to 1.5 μm is 15 to 30%, the specific surface area measured by the BET method is 5.8 to 10.1 m2/g, and the average particle size D50 according to the particle size distribution measured by laser diffraction measurement is preferably 0.6 to 1.5 μm.
US08758939B2 Anode active material for secondary battery
Disclosed is an anode active material including: a crystalline phase comprising Si and a Si-metal alloy; and an amorphous phase comprising Si and a Si-metal alloy, wherein the metal of the Si-metal alloy of the crystalline phase is the same as or different from the metal of the Si-metal alloy of the amorphous phase.
US08758938B2 Negative electrode for lithium secondary battery and lithium secondary battery
A negative electrode for a lithium secondary battery includes a negative-electrode active material having a specific surface area of Sx (m2/g) and an average particle size of Lx (μm), a fibrous conductive material having a specific surface area of Sy (m2/g) and an average length of Ly (μm), and a granular conductive material having a specific surface area of Sz (m2/g) and an average particle size of Lz (μm), in which letting the negative-electrode active material content be X, letting the fibrous conductive material content be Y, and letting the granular conductive material content be Z, Log((SyY+SzZ)/SxX×10−1)×Log((LyY+LzZ)/LxX×101) is defined as an electrode parameter, and the electrode parameter satisfies Log((SyY+SzZ)/SxX×10−1)×Log((LyY+LzZ)/LxX×101)≧0.
US08758936B2 Thin film structures
A thin film structure, method of producing it and the use thereof. The thin film structure comprises a substrate with a thin conductive layer containing an oxidizing enzyme mixed with an electron transfer mediator. The thin layer is protected against wetting to allow for its storage in dry conditions and further being sufficiently porous to allow for immediate activation of the oxidizing enzyme when contacted with an aqueous solution. The thin film can be used as a cathode in electrochemical fuel cells.
US08758935B2 Soluble polymer with multi-stable electric states and products comprising such polymer
A compound comprises a polymeric chain with a repeat unit repeated more than 5 times. The repeat unit comprises conjugated first and second cyclic groups and a plurality of side groups each bonded to one of the cyclic groups. A side group bonded to the first cyclic group is an electron donor and a side group bonded to the second cyclic group is an electron acceptor, such that the compound is switchable between first and second electrical conductive states by application of an electric field to the compound. At least one of the side groups is selected so that the compound is soluble in an organic solvent. The compound may be used in films, memory cells, or electronic devices. A layer of the compound may be formed on a surface by dissolving the compound in an organic solvent, applying the solution to the surface, and then removing the solvent.
US08758934B2 Electrolyte for lithium secondary battery and lithium secondary battery comprising the same
The present disclosure relates to an electrolyte for a lithium secondary battery, comprising a non-aqueous solvent, a lithium salt and an additive having a perfluoroalkyl group. By including the additive having a specific structure in the electrolyte, the output of the lithium secondary battery can be improved greatly.
US08758933B2 Battery with electrode arrangement in relation to the holder
A battery includes a battery cell and a battery housing. The battery cell includes arcuate portions wherein an outer circumference of the battery cell is formed at least in part to be arcuate. The battery housing includes angular portions respectively opposing the arcuate portions and for storing the battery cell therein. Support walls having substantially the same curvatures as the arcuate portions and supporting the arcuate portions are formed along an insertion direction of the battery cell.
US08758928B2 Conductive structure for an electrode assembly of a lithium secondary battery
An electrode assembly of a lithium secondary battery is specially designed such that the positive and negative layers are formed at a side thereof with a large uncoated negative lead area and a large uncoated positive lead area. In addition, the collecting area is located correspondingly to the negative lead area or the positive lead area. And then the clasping assemblies are fixed outside the positive lead area or the negative lead area. In this way, the two pressing pieces are firmly pressed against the positive lead area or the negative lead area. On the one hand, the respective layers of the positive lead area or the negative lead area are pressed closely against one another, and on the other hand, the innermost layer of the positive lead area or the negative lead area is allowed to be maintained in a tight electrical contact with the collecting area.
US08758927B2 Secondary battery
A secondary battery including a can having at least two receiving spaces with a separation space therebetween, an electrode assembly received in the receiving spaces of the can, a collector electrically connected to the electrode assembly, and a cap plate coupled to an upper portion of the can to seal the can.
US08758926B2 Separator for electrochemical device, manufacturing method thereof, and electrochemical device comprising the same
Provided is a separator for an electrochemical device including a plate-like porous substrate, and a porous thin-film coating layer formed on at least one surface of the plate-like porous substrate and containing crosslinked polyester. The crosslinked polyester coating layer hardly affects the air permeability of the separator. Also, the crosslinked polyester coating layer has good hydrophilicity and wettability to an electrolyte, and thus improves the performance of the battery. Also, the crosslinked polyester coating layer has excellent resistance to heat and deformation, and thus prevents the thermal shrinkage of the separator.
US08758925B2 Battery system containing phase change material-containing capsules in interior configuration thereof
Provided is a battery system in which an interior part of a battery structure includes phase-change particles including a capsule and phase-change materials. The phase-change materials have a high latent heat of phase change at a specific temperature, and are encapsulated in the capsule. The capsule is made of an inert material. The battery system in accordance with the present invention can prolong a service life of the battery by inhibiting temperature elevation inside the battery under normal operating conditions without substantial effects on size, shape and performance of the battery, and further, can inhibit the risk of explosion resulting from a sharp increase in temperature inside the battery under abnormal operating conditions, thereby contributing to battery safety.
US08758924B2 Extruded and ribbed thermal interface for use with a battery cooling system
A cooling manifold assembly for use in a battery pack thermal management system is provided. The cooling manifold assembly includes a coolant tube that is interposed between at least a first row of cells and a second row of cells, where the first and second rows of cells are adjacent and preferably offset from one another. A thermal interface layer is attached to the cooling tube, the thermal interface layer including a plurality of pliable fingers that extend away from the cooling tube and are interposed between the cooling tube and the first row of cells, and interposed between the cooling tube and the second row of cells, where the pliable fingers are deflected by, and in thermal contact with, the cells of the first and second rows of cells.
US08758917B2 Secondary battery
In a lithium-ion secondary battery (100), a battery case (300) has sidewalls (300A, 300B) facing toward side ends of a wound electrode body (200), the side ends being at opposite lateral sides of the positive electrode sheet (220), and of the sidewalls (300A, 300B), one of the sidewalls (300A) (positive-electrode-side sidewall) facing toward an uncoated portion (222) of the positive electrode sheet (220) is thicker than the other sidewall (300B) (negative-electrode-side sidewall). In other words, the relationship between the thickness A of the one sidewall (300A) facing toward the uncoated portion (222) of the positive electrode sheet (220) and the thickness B of the other sidewall (300B) is A>B.
US08758915B2 Module unit
A module unit includes a main body attached to a plurality of battery cells, a bus bar provided on the main body to electrically connect the battery cells, and a temperature sensor retained to the main body to measure a temperature of at least one of the battery cells. The main body has a through hole. The temperature sensor includes a retaining portion which is retained to an edge part of the through hole from a first side of the main body facing to the battery cells after the retaining portion passes through the through hole from a second side of the main body opposite to the first side with respect to the main body, and an attaching portion which has an operation part at an end part thereof and is formed so as not to pass through the through hole. When the main body is attached to the battery cells, the temperature sensor comes into contact with the at least one battery cell.
US08758914B2 Li-Ion/polysulfide flow battery
Li-Ion/Polysulfide flow battery systems are provided to achieve high energy density and long service life. The system is configured to minimize corrosion of the lithium electrode by providing an electrochemical reactor comprising a first and a second electrode configured in spaced apart relation defining an inter-electrode channel through which the sulfur electrolyte is caused to flow.
US08758910B2 Substrate for suspension, and production process thereof
The present invention provides a substrate for suspension that includes a first structural part including a metal supporting substrate, an insulating layer, a wiring layer, and a cover layer, and a second structural part formed so as to extend continuously from the first structural part and has no metal supporting substrate. A position of an edge of an upper surface of the insulating layer coincides with a position of an edge of the lower surface of the cover layer or the position of the edge of the upper surface of the insulating layer is positioned on a side closer to the wiring layer than to the position of the edge of the lower surface of the cover layer at a boundary region between the first structural part and the second structural part.
US08758906B2 Soft magnetic material, powder magnetic core and process for producing the same
A soft magnetic material includes a plurality of composite magnetic particles. Each of the plurality of composite magnetic particles has: a metal magnetic particle including iron; a lower film surrounding the surface of the metal magnetic particle and including a nonferrous metal; and an insulating upper film surrounding the surface of the lower film and including at least one of oxygen and carbon. The nonferrous metal has an affinity with the at least one of oxygen and carbon included in the upper film that is larger than such affinity of iron; or the nonferrous metal has a diffusion coefficient with respect to the at least one of oxygen and carbon included in the upper film that is smaller than such diffusion coefficient of iron. This configuration provides desirable magnetic properties.
US08758901B2 Ultrahigh-strength welded joint and production method thereof
An ultrahigh-strength welded joint with superior strength and toughness, and a method for producing the ultrahigh-strength welded joint by means of single-pass welding by using laser hybrid welding, are provided, wherein the welded joint comprising a steel plate having a plate thickness of 4 mm to 12 mm and including weld metal of almost full martensite structure, wherein, in a cross-section of the welded joint in a direction perpendicular to a welding direction, a cross-sectional shape of the weld metal has a width W1 of 2.0 to 7.0 mm at a surface of the steel plate and a width W2 of 0.5 to 2.4 mm at a position where is separated from the surface by three-quarters of the plate thickness, wherein the weld metal comprises, by mass %, C: over 0.09% to 0.24%; Si: 0.2% to 1.0%; Mn: 0.5% to 2.5%; P: 0.02% or less; S: 0.02% or less; Al: 0.004% to 0.08%; Ti: 0.005% to 0.15%; O: 0.005% to 0.05%; and Ni: 1.0% to 9%, and wherein a carbon equivalent (Ceq) is 0.40% to 1.00%, a value Y as defined by equation (([Si]+[Mn])/40+[Al]+[Ti]) is 0.07% to 0.20%.
US08758897B2 Schiff base type color conversion layer, light absorbing layer, and filter
Disclosed are a compound that emits fluorescence, particularly in its solid state, and is suited to provide a color converting material with various improved performance properties over prior art and a light emitter, a color conversion filter, a color conversion device, and a photoelectric device each containing the compound; particularly a Schiff base type compound of formula (I) and a coloring material, a color conversion layer, a light absorbing layer, a color conversion filter, a light absorbing filter, a color-converting light-emitting device, and a photoelectric device each containing the compound. The definition of the symbols in formula (I) is the same as in the specification.
US08758893B2 Enamelware and glaze
The present invention provides enamelware and a glaze improving the bondability between the steel substrate and enamel layer and superior in resistance to dew point corrosion by sulfuric acid and hydrochloric acid, that is, a steel substrate of a composition containing, by mass %, Cu: 0.05 to 0.5%, Si: 0.1 to 2.0%, Mn: 0.05 to 2.0%, P: 0.005 to 0.10%, and S: 0.005 to 0.1%, restricting C to C: 0.20% or less, and comprising a balance of Fe and unavoidable impurities on the surface of which an enamel layer of a thickness of 50 to 700 μm is provided. At that time, the content of Co oxides in the enamel layer is made, converted to Co, 0.01 to 10% and/or the content of Ni oxides is made, converted to Ni, 0.05 to 20% or the total content of Ni in the steel substrate and enamel layer is made 0.005 to 4.5% with respect to the total mass of the enamelware and/or the total content of Co is made 0.008 to 4.0% with respect to the total mass of the enamelware.
US08758892B2 Thermally conductive foam product
A compressible, thermally conductive foam interface pad is adapted for emplacement between opposed heat transfer surfaces in an electronic device. One heat transfer surface can be part of a heat-generating component of the device, while the other heat transfer surface can be part of a heat sink or a circuit board. An assembly including the foam interface pad and the opposed electronic components is also provided.
US08758884B2 Instrument display board and process for producing instrument display board
[Problem] An instrument display board is provided which does not need troublesome work for preparing plural plate members, can adopt a great variety of designs, can present a stereoscopic feeling and a high-class feeling, brings about unprecedented color tone variation, metallic texture, brilliancy in the light, etc., is very excellent in high-class feeling and design variation, has excellent appearance quality and therefore can enhance merchantability. A process for producing the instrument display board is provided.[Solution means] The instrument display board includes a light-transmitting substrate, at least one partial print layer, a different-color print layer having a color tone different from that of the partial print layer, said partial print layer and said different-color print layer being provided on a back surface of the light-transmitting substrate, and a shield member that is provided at a position on a front surface of the light-transmitting substrate, said position corresponding to a position surrounding a part or the whole of the outer periphery of a print portion of the partial print layer. A portion of the light-transmitting substrate corresponding to the partial print layer is a transparent layer. The instrument display board can present a stereoscopic feeling without using plural plate members, brings about unprecedented color tone variation, metallic texture, brilliancy in the light, etc., is very excellent in high-class feeling and design variation, has excellent appearance quality and therefore can enhance merchantability. The process of the invention can produce the instrument display board.
US08758882B2 Composite layer
Composite layer comprising a plurality of longitudinal first zones comprised of a first polymeric material alternating with a plurality of longitudinal second zones comprised of a second polymeric material such that one first zone is disposed between two adjacent second zones. The zones are generally parallel to one another, and at least one of each first zone or each second zone has a maximum width dimension of not greater than 2 mm. Adjacent first and second zones have an average pitch, wherein for the composite layer there is an average of said average pitches, and wherein the average pitch for any adjacent first and second zones is within 20 percent of the average pitch for adjacent first and second zones of said average of said average pitches.
US08758880B2 Ketopyrroles as organic semiconductors
Monomeric or polymeric compounds comprising at least one moiety of the formula (Ia) wherein X is CR, where R is H or a substituent as defined in claim 1, or is another ketopyrrole moiety e.g. of the formula (Ib) or (Ic) with this moiety and all other symbols are as defined in claim 1, show good solubility in organic solvents and excellent film-forming properties. In addition, high efficiency of energy conversion, excellent field-effect mobility, good on/off current ratios and/or excellent stability can be observed, when the polymers according to the invention are used in semiconductor devices or organic photovoltaic (PV) devices (solar cells).
US08758879B2 Composite hat stiffener, composite hat-stiffened pressure webs, and methods of making the same
There is provided a composite hat stiffener, a composite hat-stiffened pressure web, and a method of making the same. The composite hat stiffener has a composite hat section having a first side and a second side. The composite hat stiffener further has a plurality of composite stiffening plies coupled to the composite hat section. The plurality of composite stiffening plies include a body ply coupled to the first side of the composite hat section, a wrap ply coupled the body ply, and a base ply coupled to the body ply and the wrap ply. The composite hat stiffener further has a pair of radius filler noodles coupled to the composite hat section and disposed between the plurality of composite stiffening plies. The composite hat stiffener further has an outer ply coupled to the second side of the composite hat section.
US08758878B2 Method for reducing adhesion between polymer bodies
A device is disclosed that includes a first polymer body having tacky properties. The first polymer body has a substantially-flat exterior surface. One or more protrusions are disposed on the substantially-flat exterior surface of the first polymer body. When the one or more protrusions are in contact with a substantially-flat exterior surface of a second polymer body having tacky properties, the adhesive force between the one or more protrusions and the substantially-flat exterior surface is less than the force of gravity on the first polymer body.
US08758874B2 Prepreg base material, layered base material, fiber-reinforced plastic, process for producing prepreg base material, and process for producing fiber-reinforced plastic
A laminated base material includes a lamination and integration of prepreg base materials each of which includes many reinforcing fibers arranged substantially in one direction and a matrix resin adhered to the reinforcing fibers, wherein at least one of the laminated prepreg base materials is formed with a prepreg base material having, throughout its whole surface, many incisions each extending in a direction crossing the reinforcing fibers, substantially all of the reinforcing fibers divided by incisions, and wherein a length L of each of reinforcing fiber segments formed by the incisions is 10 to 100 mm, a thickness H of the prepreg base material is 30 to 300 μm, and a fiber volume content Vf of the reinforcing fibers is 45 to 65% and arranging directions of the reinforcing fibers between one and another laminated prepreg base materials have at least two directions different each other.
US08758871B2 Liquid crystal display and method for manufacturing same
A liquid crystal display is provided which is capable of reducing the occurrence of defective display due to variations in the initial alignment direction of a liquid crystal alignment control film in a liquid crystal display of an IPS scheme, realizing the stable liquid crystal alignment, providing excellent mass productivity, and having high image quality with a higher contrast ratio. The liquid crystal display has a liquid crystal layer disposed between a pair of substrates, at least one of the substrates being transparent, and an alignment control film formed between the liquid crystal layer and the substrate. At least one of the alignment control films 109 comprises photoreactive polyimide and/or polyamic acid provided with an alignment control ability by irradiation of substantially linearly polarized light.
US08758870B2 Liquid crystal composition, liquid crystal element, and liquid crystal display device
A novel liquid crystal composition that can be used for a variety of liquid crystal devices is provided. A stable liquid crystal element that is driven at low voltage and that withstands physical impact is provided with the use of the novel liquid crystal composition. A highly reliable liquid crystal display device with low power consumption and high display quality is provided with the use of the liquid crystal element. The liquid crystal composition exhibits a blue phase and contains nematic liquid crystal, 1,4:3,6-dianhydro-2,5-bis[4-(n-hexyl-1-oxy)benzoic acid]sorbitol (abbreviation: ISO-(6OBA)2) represented by the structural formula (100) as a first chiral agent, and (4R,5R)-4,5-bis[hydroxy-di(phenanthren-9-yl)methyl]-2,2-dimethyl-1,3-dioxolane (abbreviation: R-DOL-Pn) represented by the structural formula (101) as a second chiral agent.
US08758869B2 Optical element
An optical element is provided. The optical element is a light-dividing element, for example an element that can divide incident light into at least two kinds of light having different polarized states. The optical element can be used to realize a stereoscopic image.
US08758867B2 Neutral ligand containing precursors and methods for deposition of a metal containing film
Methods and compositions for depositing metal films are described herein. In general, the disclosed methods utilize precursor compounds comprising gold, silver or copper. More specifically, the disclosed precursor compounds utilize neutral ligands derived from ethylene or acetylene.
US08758866B2 Process for producing composite of metal and resin
The metal part is one where a carboxyl group or an amino group, or a hydroxyl group is imparted onto the surface. On the other hand, the resin part is one into which an adhesiveness modifier containing an epoxy group is blended. A process for producing a composite of metal and resin, wherein the metal part and the resin part are bonded by interaction of the carboxyl group or the amino group, or the hydroxyl group with the epoxy group.
US08758862B2 Coating compositions with an isocyanate-functional prepolymer derived from a tricyclodecane polyol, methods for their use, and related coated substrates
Coating compositions include (a) an isocyanate functional prepolymer derived from a polyisocyanate and a tricyclodecane-containing polyester polyol; and (b) a blocked amine curing agent.
US08758861B2 Insulating glass sealant
A two-part sealant composition, wherein this composition comprises a first part and a second part. The first part comprises a polymer selected from a silane-terminated polyurethane or a silane-terminated polyether, wherein this polymer is present in an amount of up to 100% by weight of the first part of the sealant composition. The second part comprises a plasticiser that it is compatible with the polymer and a filler comprising at least 0.5% by weight of residual water, wherein the filler comprises at least one rheological filler, and wherein the filler is present in an amount of 80-20% by weight of the second part of the sealant composition. The first and second parts are separated from one another, and the amount of polymer present in the first part makes up 4-50% by weight of the first and second parts taken together. In use, the first and second parts are mixed to achieve a cured substance having a 48 hour Shore A hardness in the range of 25-70.
US08758860B1 Process for incorporating an ion-conducting polymer into a polymeric article to achieve anti-static behavior
A process for endowing a polymeric article with a surface layer of an ion-conducting polymer to yield electrical surface resistivity sufficiently low for electrostatic discharge applications is provided. The polymeric article contains one or more immobilized, polymeric components having amine functional groups. The presence of the ion-conducting polymer in the surface layer lowers the surface electrical resistivity into the range suitable for electrostatic discharge applications, between about 1×105 and about 1×1012Ω/□. Plastic electrostatic dissipation materials produced by the inventive process may find use in the optical, electronics, automotive, entertainment, sporting goods, and medical sectors.
US08758859B2 Housing and method for making same
A housing includes a plastic substrate, an active layer formed on the plastic substrate, and an exterior layer formed on the active layer. The active layer contains polysiloxane and cetyl trimethyl ammonium bromide. The exterior layer contains silicon dioxide or titanium dioxide, and cetyl trimethyl ammonium bromide.
US08758858B2 Method of producing a plasma-resistant thermal oxide coating
A method of creating a plasma-resistant thermal oxide coating on a surface of an article, where the article is comprised of a metal or metal alloy which is typically selected from the group consisting of yttrium, neodymium, samarium, terbium, dysprosium, erbium, ytterbium, scandium, hafnium, niobium or combinations thereof. The oxide coating is formed using a time-temperature profile which includes an initial rapid heating rage, followed by a gradual decrease in heating rate, to produce an oxide coating structure which is columnar in nature. The grain size of the crystals which make up the oxide coating is larger at the surface of the oxide coating than at the interface between the oxide coating and the metal or metal alloy substrate, and the oxide coating is in compression at the interface between the oxide coating and the metal or metal alloy substrate.
US08758855B2 Coating film forming apparatus, use of coating film forming apparatus, and recording medium
A coating film forming apparatus that holds a substrate upon a spin chuck and forms a coating film by supplying a chemical liquid upon a top surface of said substrate comprises: an outer cup provided detachably to surround the spin chuck; an inner cup provided detachably to surround a region underneath the substrate held upon the chuck; a cleaning nozzle configured to supply a cleaning liquid for cleaning a peripheral edge part of the substrate, such that the cleaning liquid is supplied to a peripheral part of a bottom surface of the substrate; a cutout part for nozzle mounting, the cutout part being provided to the inner cup to engage with the cleaning nozzle; and a cleaning liquid supply tube connected to the cleaning nozzle, the cleaning nozzle being detachable to the cutout part in a state in which the cleaning liquid supply tube is connected.
US08758853B2 Process and apparatus for producing coated particles
The invention is directed to a process and apparatus for preparing coated particles, in particular a process for preparing particles that are coated with small particles using electrospraying. The coated particles produced according to the present invention find use for instance as catalysts or as pharmaceuticals. According to the invention a host particle is contacted in a gas stream where it is allowed to contact with one or more moving tribocharging particles, thus providing a charged host particle, which is subsequently contacted with charged guest particles in an electrospraying step.
US08758852B2 Method for patterning nanomaterial using solution evaporation
Disclosed is a method for patterning a nanomaterial using solution evaporation. More particularly, the method for patterning a nanomaterial using solution evaporation includes; coating the nanomaterial with a polymer material and uniformly dispersing the coated nanomaterial in a solvent to prepare a solution containing the nanomaterial, and pouring the nanomaterial-containing solution on a substrate, enabling the nanomaterial to be patterned after evaporation of the solvent.
US08758851B2 Method for increasing the durability of glass
A method for increasing the durability of glass by a coating, according to the present invention comprises the step of coating glass with a coating comprising at least one layer whose thickness is below 5 nanometers, wherein the coating comprises a compound of at least one element.
US08758847B2 Apparatus and methods for making coated liners and tubular devices including such liners
A medical device includes a proximal end, a distal end sized for introduction into a body lumen, and a lumen extending between the proximal and distal ends. The tubular device includes an inner liner including a coating on an inner surface thereof, a reinforcing layer surrounding at least a portion of the liner; and an outer layer surrounding the reinforcing layer and inner liner. The liner and outer layer may include multiple sections having different properties than one another, adjacent sections attached together by seams, which may be offset from one another. Apparatus and methods for making tubular devices with coated liners are also provided.
US08758844B2 Method for the production of coffee
A method for the production of drinks, particularly coffee, even more particularly “American type coffee” or filter coffee by means of a machine and a capsule containing a proportion of preparation for drink is disclosed. The method includes the phases of heating a liquid for the preparation of drinks, putting under pressure the liquid within a boiler, feeding the liquid to the capsule with crossing of the capsule, taking the liquid after this phase of crossing of the capsule. The method also includes an infusion and remixing phase of the liquid with the preparation for drink within the capsule, which occurs within a housing partially filled up with the preparation for drink according to a filling factor in the range from 35 to 90%, preferably in the range from 40 to 85%, even more preferably in the range from 45 to 75%.
US08758842B2 Process for producing 1,4-dihydroxy-2-naphthoic acid
A process for producing 1,4-dihydroxy-2-naphthoic acid, comprising initiating the culture of 1,4-dihydroxy-2-naphthoic acid producing bacteria belonging to propionic acid bacteria under anaerobic conditions and culturing the bacteria under aeration into a medium when the concentration of a carbon source in the medium is 3.5% by mass or less.
US08758838B2 Anti-inflammatory compositions and methods of use
Provided are anti-inflammatory compositions comprising (a) an anti-inflammatory agent selected from the group consisting of olive leaf extract, holly herb, sappan wood, feverfew, and combinations of two or more thereof, and (b) an anti-inflammatory agent comprising at least one lipophilic aminoacid and at least one metal salt. Also provided are personal care products comprising such compositions, and methods of use thereof.
US08758832B1 Oral or enteral dosage forms containing phytochemicals from pomegranates
Nutraceutical compositions for improved administration of important phytochemicals from pomegranate to a human or animal. More particularly, enables oral or enteral dosage forms containing phytochemicals from pomegranate for administering on a routine basis. In at least one instance the natural contents of a pomegranate are encapsulated into a pill form or concentrated juice that provides for more efficient administration than eating a pomegranate but contains the same key ingredients present in the fruit. Enables the recipient to receive the benefits of the fruit but allows for the dosages to be taken in pill or concentrated juice form. Composition is chemically similar or equal to a natural pomegranate but is in a powder, pill or concentrated liquid form.
US08758827B2 Local system for the release of active principle and process for its manufacture
A local system for the release of active principle is described which consists of approximately spherical or rotation symmetrical bodies which are composed essentially of polymethyl methacrylate or polymethyl methacrylate co-methyl acrylate, zirconium dioxide or barium sulphate and one or more pharmaceutical active principles, in particular antibiotics, and which are produced by radical polymerization, radical polymerization activators effective in the temperature range of 10-80° C. or residues of these polymerization activators from the groups of aromatic amines, heavy metal salts and barbiturates not being contained therein.A process for the production of the local system for the release of active principle in the case of which a) a paste is produced by mixing methyl methacrylate, polymethyl methacrylate or polymethyl methacrylate co-methyl acrylate, zirconium dioxide and/or barium sulphate, one or more pharmaceutical active principles and a thermally decomposing radical initiator, the paste having a viscosity such that it cannot be deformed at room temperature by the effect of gravity; b) the paste is injection molded by an injection molding device without heating at room temperature into approximately spherical or rotation-symmetrical bodies or the approximately spherical or rotation symmetrical bodies are injection-molded onto a wire; c) the bodies are heated to a temperature at which the polymerization initiator decomposes.
US08758821B2 Oral formulations of ospemifene
This invention relates to a liquid or semisolid oral drug formulation comprising a therapeutically active compound of the formula (I) or a geometric isomer, a stereoisomer, a pharmaceutically acceptable salt, an ester thereof or a metabolite thereof, in combination with a pharmaceutically acceptable carrier.
US08758815B2 Pharmaceutical compositions comprising a combination of metformin and sitagliptin
The present invention relates to a pharmaceutical composition, preferably a pharmaceutical dosage form, comprising at least two separate compartments, wherein one compartment contains a composition comprising metformin or a pharmaceutically acceptable salt thereof and wherein another compartment contains a composition comprising sitagliptin.The present invention also relates to a process for preparing dosage forms comprising metformin or a pharmaceutically acceptable salt thereof and sitagliptin or a pharmaceutically acceptable salt thereof, the process comprising the steps of: a) providing one composition containing metformin or a pharmaceutically acceptable salt thereof and optionally also sitagliptin, b) providing a further composition containing sitagliptin or a pharmaceutically acceptable salt thereof and optionally also metformin, and c) combining the compositions to form compartments. The present invention also refers to a process for preparing dosage forms comprising at least one compartment comprising metformin or a pharmaceutically acceptable salt thereof and sitagliptin or a pharmaceutically acceptable salt thereof, the process comprises providing a composition containing metformin or a pharmaceutically acceptable salt thereof, and sitagliptin or a pharmaceutically acceptable salt thereof, and a matrix agent.Moreover, the present invention related to a dosage form obtained by said process, and to the use of said dosage form for the treatment of diabetes.
US08758811B2 Biofunctionalized phospholipid-capped mesoporous silica nanoshuttles for targeted drug delivery
The present invention provides a multilayer vehicle, including a mesoporous silica core and a lipid bilayer coating thereon. Hydrophobic molecules are formed between the silica core and lipid layer. Additionally, methods and uses of the multilayer vehicle are also provided.
US08758809B2 Skin treatment compositions containing copper-pigment complexes
A therapeutic method is described in which copper is delivered into the skin as a complex with sodium chlorophyllin. Sodium copper chlorophyllin is encapsulated in suitable lecithin-type liposomes, containing a high concentration of linoleic acid and having diameters in the range 150-350 nanometers. The method provides therapeutic benefits in the treatment of environmentally-induce premature skin aging, excessively oily skin, acne and acne-related skin disorders, acne-rosacea, and also stimulates the natural tanning response of skin to sunlight and other ultraviolet-containing radiation.
US08758806B2 Human lubrication gel
Human lubricating gels, methods and kits for delivering a therapeutic agent to a target tissue site beneath the skin of a patient utilizing human lubricating gel are provided, the human lubricating gel being capable of adhering to the target tissue site and comprising one or more biodegradable formulations containing an effective amount of the therapeutic agent. In various embodiments, the human lubricating gel is sprayable and hardens after contacting the target tissue site.
US08758796B2 Functionalizing implantable devices with a poly (diol citrate) polymer
The present invention is directed to a novel poly(diol citrates)-based coating for implantable devices. More specifically, the specification describes methods and compositions for making and using implantable devices coated with citric acid copolymers or citric acid copolymers impregnated with therapeutic compositions and/or cells.
US08758794B2 Cell-free tissue replacement for tissue engineering
The present invention is a natural, cell-free tissue replacement that does not require difficult or extensive preparation made by washing tissue replacement in a solution including one or more sulfobetaines and an anionic surface-active detergent and washing the tissue replacement in serial solutions of the buffered salt to remove excess detergent. The natural, cell-free tissue replacement may be a nerve graft that supports axonal regeneration, guides the axons toward the distal nerve end and/or is immunologically tolerated. Other forms of the invention are a composition and kit prepared by the method of making a native, cell-free tissue replacement. The present invention may be modified for use in diagnostic, therapeutic, and prophylactic applications.
US08758792B2 Bone matrix compositions and methods
Osteoinductive compositions and implants having increased biological activities, and methods for their production, are provided. The biological activities that may be increased include, but are not limited to, bone forming; bone healing; osteoinductive activity, osteogenic activity, chondrogenic activity, wound healing activity, neurogenic activity, contraction-inducing activity, mitosis-inducing activity, differentiation-inducing activity, chemotactic activity, angiogenic or vasculogenic activity, and exocytosis or endocytosis-inducing activity. In one embodiment, a method for producing an osteoinductive composition comprises providing partially demineralized bone, treating the partially demineralized bone to disrupt the collagen structure of the bone, and optionally providing a tissue-derived extract and adding the tissue-derived extract to the partially demineralized bone. In another embodiment, an implantable osteoinductive and osteoconductive composition comprises partially demineralized bone, wherein the collagen structure of the bone has been disrupted, and, optionally, a tissue-derived extract.
US08758788B2 Fungicidally active compound combinations
Active compound mixtures comprising ipconazole and at least one further fungicidally active compound are highly suitable for protecting industrial materials against colonization and destruction by microorganisms.
US08758787B2 Long-lasting insect repellant, pesticide and antifeedant compositions
An insect repellent material includes a carrier such as a polyethylene, a molecular sieve or zeolite material, and a repellent such as geraniol. The molecular sieve/zeolite material provides the insect repellent material with a slow-release quality and also permits the carrier to hold more insect repellent than it would otherwise if so desired.
US08758786B2 Preparation for reducing and/or preventing body fat and respective uses, in particular together with a dressing material
The present invention relates to human metabolism, in particular fat reduction and a cosmetic and pharmaceutical formulation, as well as respective uses in particular together with a dressing material according to the invention.
US08758785B2 Composition for external use and method for producing the same
A composition for external use containing a physiologically acceptable salt of a tranexamate as an active ingredient, which is dispersed in the composition in the state of fine particles, is provided. Thereby, a physiologically acceptable salt of the tranexamate is dissolved in a solvent to prepare a solution, to which a salting-out agent is added to precipitate the salt. Such salt is so dispersed in a composition for external use in the state of fine particles that the tranexamate salt can be mixed without using a large amount of an oil component to obtain a composition for external use affording excellent feel of use and stability.
US08758784B2 Treatment and composition for achieving skin anti-aging benefits by corneum protease activation
Novel methods and compositions for treating aged and environmentally damaged skin are disclosed which provide improvements in the skin's visual appearance, function and clinical/biophysical properties by activating at least one proteolytic enzyme in the skin's stratum corneum. The disclosed treatment methods involve topical application of a novel cosmetic composition containing a combination of a cationic surfactant such as N,N-dimethyldodecyl amine oxide (DMDAO), an anionic surfactant such as sodium dodecyl sulfate (SDS), or monoalkyl phosphate (MAP) and a chelating agent such as ethylene diamine tetraacetate (EDTA) to stimulate a chronic increase in the replacement rate of the skin's stratum corneum by means of corneum protease activation. This chronic, low level stimulation is effective to induce repair and replacement of the stratum corneum, epidermis, and dermis of the skin and improvements in the appearance, function, and anti-aging properties of the skin.
US08758781B2 Tissue scaffolds derived from forestomach extracellular matrix
The present invention pertains to the development of Extracellular Matrix (ECM) scaffolds derived from the forestomach of a ruminant. Such scaffolds are useful in many clinical and therapeutic applications, including wound repair, tissue regeneration, and breast reconstruction. In addition, the present invention features methods of isolating ECM scaffolds from mammalian organs, including but not limited to the ruminant forestomach. The invention further features laminated ECM scaffolds containing a polymer positioned between individual ECM sheets. The polymer may optionally contain bioactive molecules to enhance the functionality of the scaffold.
US08758780B2 Subcutaneous paliperidone composition
The present invention relates to pharmaceutical composition for subcutaneous injection comprising a paliperidone compound wherein the composition releases the paliperidone with an immediate onset of action and continuously for at least 3 weeks, and wherein the composition has a pharmacokinetic profile in vivo with substantially no burst release of the paliperidone. The compositions are useful as medicaments for the treatment of psychotic disorders and diseases.
US08758774B2 Bivalent vaccine for marine fish and method for making the same
A bivalent vaccine against Scuticociliatosis, Vibriosis and marine ich in zobaidy, sobaity and hamoor includes a formalin killed whole cell Vibrio encapsulated Uronema spp. The vaccine is made by collecting a mass of infected zobaidy and scraping the moribund fish with a plastic spatula to transfer live Uronema into a pretri dish. The cerebro-spinal fluid is removed from the zobaidy and added to the fluid containing the Uronema at different concentrations formed with the BHIB. A mass of zobaidy juvenile are fed a commercial pellet feed coated with formalin inactivated Uronema spp. encapsulated in Vibrio four times a day for a period of ten days.
US08758771B2 Bacterial virulence factors and uses thereof
The invention relates to, in part, secreted proteins of bacterial pathogens and methods for their use. More specifically, the invention provides in part several new common secreted proteins for A/E pathogens. In some embodiments of the invention, these polypeptides and nucleic acid molecules encoding these polypeptides, or portions thereof, are useful as vaccines, diagnostics, or drug screening tools for A/E pathogenic infections, or as reagents.
US08758765B2 Compositions and methods related to Staphylococcal bacterium proteins
The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve an EsaC polypeptide.
US08758761B2 Combination therapies for treating type 1 diabetes
In accordance with the subject invention, combination therapies can be used to modulate a patient's immune response in order to prevent, delay and/or reverse type 1 diabetes.
US08758756B2 Anti-human epidermal growth factor receptor antibody and uses thereof
An anti-human epidermal growth factor receptor (EGFR) antibody including an amino acid sequence as set forth in SEQ ID No. 3 is provided. The antibody binding to a labeling agent and used for labeling cells is also provided. A novel method for screening an anti-EGFR antibody is further provided.
US08758742B1 Prebiotic and preservative uses of oil emulsified probiotic encapsulations
An encapsulation system is provided comprising nitrogen-purge, instant bonding encapsulation method. Specifically, the encapsulation system comprises a composition, a two-piece capsule comprising a capsule cap and a capsule body; a gas to purge oxygen from the composition within the capsule; and a sealing solution to seal the capsule cap to the capsule body. Associated methods for encapsulating compositions using the encapsulation system are also provided.
US08758729B2 Oral compositions containing polyguanidinium compounds and methods of manufacture and use thereof
The invention describes the modification of polyamine-based materials to form polyguanidine compounds that are useful for their antimicrobial, anticaries, and muccoadhesive properties. The present invention also relates to methods for preventing or treating periodontal disease and caries which include delivering a therapeutically effective amount of an oral composition containing a polyguanidine compound into an oral cavity.
US08758724B2 Unnatural amino acid radiolabeling precursor
It is intended to provide a novel amino acid organic compound which can be used as a labeling precursor compound for radioactive halogen-labeled amino acid compounds including [18F]FACBC, and which prevents methanol from remaining in the radioactive halogen-labeled amino acid compounds produced therefrom. The novel amino acid organic compound is a compound represented by the following formula: wherein n is an integer of 0 or of 1 to 4; R1 is an ethyl, 1-propyl or isopropyl substituent; X is a halogen substituent or a group represented by —OR2; R2 is a straight-chain or branched-chain haloalkylsulfonic acid substituent with one to 10 carbon atoms, trialkylstannyl substituent with 3 to 12 carbon atoms, fluorosulfonic acid substituent or aromatic sulfonic acid substituent; and R3 is a protective group.
US08758722B2 Method for producing hydrogen aimed at storage and transportation
Provided is a method for producing hydrogen aimed at storage and transportation, by which hydrogen for storage and transportation that is necessary for smoothly performing an organic chemical hydride method can be industrially produced efficiently at low cost. The method is a method for producing hydrogen aimed at storage and transportation in an organic chemical hydride method, in which: the hydrogenation process of an aromatic compound uses, as a hydrogen source for the reaction of the aromatic compound, a reaction gas is produced by a reforming reaction and adjusted a hydrogen concentration from 30 to 70 vol % by a shift reaction; and a hydrogenated aromatic compound is separated from a reaction mixture obtained in the hydrogenation process, which is followed by purification.
US08758719B2 Process for converting FGD gypsum to ammonium sulfate and calcium carbonate
A continuous countercurrent flow process for converting FGD gypsum to ammonium sulfate and calcium carbonate including countercurrent flows with internal recycle of liquids to maximize the purity of reaction products while minimizing reaction times, and further include embodiments of the process that provide a yield of both ammonium sulfate and calcium carbonate to be 97 to 100%, and embodiments that provide for processes having a total time of reaction being 8 to 12 minutes, the invention further including processes for removing contaminants from the FGD gypsum employing an acid rinse process and/or a slurry tank reactor process.
US08758718B2 Low temperature sulphur dioxide oxidation catalyst for sulfuric acid manufacture
Improved catalysts for oxidation of sulfur dioxide which are alkali metal-promoted vanadium catalysts which are further promoted by gold. Improved methods employing such catalyst for oxidation of sulfur dioxide and for manufacture of sulfuric acid. Improved methods for multiple step oxidation of sulfur dioxide in which the last oxidation step is carried out employing improved catalysts of this invention at temperatures lower than 400° C.
US08758716B2 Composition containing single-walled nanotubes
An atmosphere of a carbon source comprising an oxygenic compound is brought into contact with a catalyst with heating to yield single-walled carbon nanotubes. The carbon source comprising an oxygenic compound preferably is an alcohol and/or ether. The catalyst preferably is a metal. The heating temperature is preferably 500 to 1,500° C. The single-walled carbon nanotubes thus obtained contain no foreign substances and have satisfactory quality with few defects.
US08758715B2 Porous wall hollow glass microspheres as a medium or substrate for storage and formation of novel materials
Porous wall hollow glass microspheres are provided as a template for formation of nanostructures such as carbon nanotubes, In addition, the carbon nanotubes in combination with the porous wall hollow glass microsphere provides an additional reaction template with respect to carbon nanotubes.
US08758713B2 Method for photooxidation of carbon monoxide in gas phase to carbon dioxide
The invention provides a method for oxidizing carbon monoxide present in an oxygen-containing gas phase to carbon dioxide which comprises: adsorbing the carbon monoxide onto porous silica; and irradiating the porous silica with ultraviolet ray. In the invention, mesoporous silica or amorphous silica is used as the porous silica. In particular, silica gel that is amorphous silica is preferably used.
US08758707B2 Staining instruments and methods
An apparatus and method for applying reagents to tissue mounted on slides, in the field of histology is disclosed. The apparatus holds a number of slides, in slide trays, which are loaded onto the apparatus. Each slide tray forms a batch of slides, with all the batched forming a group. The apparatus holds a number of reagents, grouped into a first group comprising bulk type reagents, and a second group comprising antibodies or probes, and detection systems, for identifying elements of the tissue. A group fluid dispenser, in the form of a robot arm, dispense reagents to the group of slides. Each batch of slides has its own batch fluid dispenser to dispense reagents onto the batch of slides. In on embodiment, the group fluid dispenser dispense antibodies, probes, detection reagents to all slides depending on the protocol defined for each slide, and the batch dispensers dispense bulk reagent to each batch, thus freeing the group fluid dispense from dispensing bulk reagents to all slides.
US08758704B2 Microfluidic diagnostic device
A method of making a microfluidic diagnostic device for use in the assaying of biological fluids, whereby a layer of adhesive in a channel pattern is printed onto a surface of a base sheet and a cover sheet is adhered to the base sheet with the adhesive. The layer of adhesive defines at least one channel, wherein the channel passes through the thickness of the adhesive layer.
US08758703B2 Device and method for diluting a sample
The present invention provides a pump device 50 which is usable to dilute a sample 52 before analysis. A first pump 54 pumps the sample to a mixing region 58 where it mixes with a diluent 66. A second pump 64 pumps the diluted sample to the analysis instrument. The flow of the diluent to the mixer is equal to the difference of the flow of the sample to the mixer and the flow of the diluted sample to the instrument. Pumps 54 and 64 are independently controllable by a controller unit which is arranged so that data from the instrument can be used to determine the dilution factor of the sample. Thus, the controller can control this dilution factor in real time, upon receipt of such data from the instrument, by change either one of (or both) the pump's flow rate.
US08758701B2 Reagent reservoir system for analytical instruments
The invention provides a reagent reservoir system and disposable reaction cassettes using the same. In one aspect, such system comprises a chamber in which dried reagent, particularly lyophilized reagent, is constrained to remain in a defined region of the chamber by a retaining member that obstructs passage of such reagents to other regions of the chamber where they may escape hydration or activation.
US08758699B2 Apparatus for control of on site mixing of solid peroxide source and catalyst
An apparatus for controlling on site generation and mixing of a two or more part chemistry, such as a peroxide source and a catalyst. In particular, the invention discloses an apparatus and dispensing method for separating solid surfaces that undergo an uncontrolled, continuous reaction when contacted with water and allows for delivery of solid reactive chemistries at the same time in a standard spray from the bottom dispensing configuration while preventing continued reaction after the dosing is complete.
US08758690B2 Sterilisation indicator
A sterilization indicator having a compound that is of the heating type when put into contact with atoms of oxygen O and/or nitrogen N; and a thermochromic dye, in thermal contact with the compound.
US08758689B2 Reaction analysis apparatus, recording medium, measurement system and control system
The present invention is capable of determining that a reaction region is in an abnormal reaction state precisely with high reproducibility, executing proper analysis processing in accordance with the determined a state of the reaction region, and efficiently analyzing a characteristic of the reaction region. The present invention obtains intensity values of first and second wavelength components by measurement of light emitted from the reaction region with a spectrometer. A relative intensity calculator calculates relative intensity of the first wavelength component relative to the second wavelength component from the intensity values of the first and second wavelength components. The apparatus determines whether or not the calculated relative intensity is a value within a predetermined range. An output portion provides notification that the state of the reaction region is a predetermined state when it is determined that the relative intensity is within the predetermined range.
US08758685B2 Automatic analyzer and operating method for same
An automatic analyzer is free from limitations on layout of various mechanisms, and thus causing no bottlenecks, for example, in a space-saving design of the automatic analyzer. This invention includes a coaxial planar duplex arrangement of two dilution disks each with annularly disposed dilution cells, and the dilution disks A and B operate independently of each other. Various mechanisms (parent-sample sampling mechanism, diluent delivery mechanism, diluent/sample mixing mechanism, and diluted-sample sampling mechanism) used in a dilution process can each access the two dilution disks. The dilution process for a parent sample, executed on the dilution disks A and B, can be continuously conducted by providing a fixed delay in operational timing between the two dilution disks.
US08758682B2 Method and device for small scale reactions
The present invention relates to a method and a device for small scale reactions, such as sample preparation of a desired substance in a sample. In the method using the device samples mixed with functionalized magnetic particles are magnetically transferred between different working stations on the device. The method uses a hydrophobic surface, such as a Petri dish, provided with hydrophilic spots of, for example, agarose beads located on said hydrophobic surface and provided with buffers, reactants or ligands.
US08758680B2 Method and device for cleaning air
The present invention is to provide an air cleaning method and device that realize sufficient purification of polluted air, high-efficiency removal of germs or the like from polluted air, and has a relatively simplified structure.
US08758678B2 Machine and method for producing and dispensing liquid or semi-liquid consumer food products
A machine for producing and dispensing liquid and semi-liquid consumer food products such as ice creams, whipped cream, yogurt and the like comprises a container for a basic product of the consumer food product, a feed and treatment circuit for the basic product, comprising a feed pump, dispensing means positioned at an outfeed end of the feed and treatment circuit, and a device for checking the bacterial load of the product during production/dispensing; an electronic control unit controlling and regulating the various steps for measuring the bacterial load.
US08758667B2 Cold press and method for the production of green compacts
A cold press and a method for the production of green compacts for diamond-containing tool segments includes a tool matrix, a top ram and a bottom ram assigned to a matrix adapter from opposite directions for the purpose of compressing sinterable metal powder and diamond granules after both of these materials have been fed to the matrix adapter. Step-by-step build-up of the green compact is carried out in such a manner that after one layer of metal powder and one layer of diamond granulate have been charged, these layers are together compressed.
US08758663B2 Device for making objects by applying material over a surface
A device for making an object comprises a substantially flat surface, an applicator, and a controller. The applicator is operable to project at an elevation angle without a substantial downward component a material used to make the object towards the substantially vertical flat surface. The controller is adapted to receive instructions for making the object and is configured to coordinate relative movement of the applicator and the surface and the application of the material by the applicator such that the material applied over at least one portion of the surface as a plurality of individually determined layers. In use the object is made adjacent to the surface.
US08758662B2 Nitrile rubber article having natural rubber characteristics
An improved process and material for making elastomeric nitrile rubber articles is disclosed. In particular, the process and material formulation can produce nitrile rubber based articles, which exhibit force-strain characteristics that are comparable to those of natural rubber latex articles, while maintaining the tensile strength properties of nitrile rubber. The process includes an accelerator composition at the pre-cure stage having a dithiocarbamate, a thiazole, and a guanidine compound. The invention also includes an elastomeric nitrile rubber product made by the process, such as examination, surgical, or work gloves.
US08758656B2 Process for producing graphite film and graphite film produced thereby
In order to obtain a graphite film having an excellent thermal diffusivity, a high density, and excellent flatness without flaws, recesses and wrinkles on the surface, the process for producing a graphite film according to the present invention comprises the graphitization step for a raw material film made of a polymer film and/or a carbonized polymer film and/or the post-planar pressurization step for the film in this order to prepare a graphite film, wherein the graphitization step is a step of thermally treating two or more stacked raw material films at a highest temperature of 2,000° C. and includes a method of electrically heating the raw material films themselves and/or a method of thermally treating the films while applying pressure to the films planarly, and the post-planar pressurization step includes a method of planarly pressurizing the one raw material film or the multiple stacked raw material films after graphitization by single-plate press or vacuum press.
US08758655B2 Optical film and method of manufacturing the same
The present invention provides an optical film and a retardation film that each include an acryl resin, and 20 to 65 parts by weight of a graft copolymer including a conjugated diene rubber based on 100 parts by weight of the acryl resin, and an electronic device including the same.
US08758652B2 Tungsten cathode material
A tungsten cathode material to be used for TIG welding, plasma spraying, plasma cutting, electro-discharge machining, discharge lamps, and the like is improved; use of the radioactive element thorium is reduced; and a long life and a high performance are realized. In a tungsten cathode material, oxide particles containing an oxide or oxides of at least one selected from the group consisting of Sm, Nd, Gd, and La in a total amount of 50 vol % or more are dispersed, the oxide particles having an average particle diameter d satisfying the relationship 0
US08758651B2 Conductive slurry for solar battery and preparation method thereof
A conductive slurry for a solar battery is disclosed, which comprises a first-order aluminum powder having a median diameter D50 of about 2-8 um, a second-order powder having a median diameter D50 of about 20-100 nm, a glass powder, and an organic carrier. The conductive slurry may be stable on a screen without leakage through screen, and there are no agglomeration and sedimentation during long-time storage. A method of preparing a conductive slurry for a solar battery is also disclosed, which comprises steps of mixing a first-order aluminum powder, a second-order powder, a glass powder, and an organic carrier to obtain a mixture; and then ball milling the mixture to obtain the conductive slurry. The method may be simple and easy to realize, so that it's advantageous for mass production in the industry.
US08758650B2 Graphene-based thermopile
Graphene-based thermopiles are provided. The graphene-based thermopiles may include thermocouples having one or more graphene strips that may be polarized to adjust their Seebeck coefficients. The polarized graphene strips may have larger Seebeck coefficients than the materials conventionally used in thermopile devices. As a result, the graphene-based thermopiles may generate large output voltages using fewer thermocouples than conventional thermopile devices.
US08758648B2 Stabilizer of color former and use thereof
The present invention provides a stabilizer that can stabilize a salt of 10-(carboxymethylaminocarbonyl)-3,7-bis(dimethylamino)phenothiazine or a derivative thereof even under the existence of moisture or under light irradiation. A compound described in at least one of (1) and (2) below is used as the stabilizer of the salt of 10-(carboxymethylaminocarbonyl)-3,7-bis(dimethylamino)phenothiazine or the derivative thereof. (1) a surfactant having an alkyl group with a carbon number of 8 to 16 (2) at least one pigment substance selected from the group consisting of a compound represented by the following formula (I), a compound represented by the following formula (II), and a flavonoid pigment
US08758647B2 Method for producing syngas
Process for the endothermic, catalytic gas phase oxidation of hydrocarbons with steam and carbon dioxide to hydrogen and carbon monoxide (synthesis gas), performed in 5 to 30 series-connected reaction zones under adiabatic conditions.
US08758645B2 Blue phase liquid crystal composition, blue phase liquid crystal material and method for manufacturing thereof
A blue phase liquid crystal material includes a liquid crystal host, a chiral reagent and a stable polymer. The chiral reagent is R811. The stable polymer is formed by photo-polymerizing a first monomer and a second monomer. The first monomer is 2-ethylhexyl acrylate (2-EHA), and the second monomer is 2-methyl-1,4-bis{4-[3(-acrylate)propoxyl]benzoicacid}phenylester (PTPTP). The blue phase liquid crystal material has a blue phase temperature range widened to an extremely low temperature. A blue phase liquid crystal composition and a method for manufacturing the blue phase liquid crystal material by using the blue phase liquid crystal composition are also provided.
US08758644B2 Oxygen-scavenging materials and articles formed therefrom
An oxygen-scavenging component and methods for producing the oxygen-scavenging component are provided. The oxygen-scavenging component, which in preferred embodiments is suitable for use in packaging articles, includes an oxygen-scavenging group preferably having at least one double bond. The oxygen-scavenging component may be combined with a polymer and/or an oxidation catalyst to form an oxygen-scavenging composition.
US08758642B2 Compositions and methods for reducing fire hazard of flammable refrigerants
The present invention relates to compositions comprising flammable refrigerant, fire hazard-reducing agent, and optionally a lubricant suitable for use in a refrigeration or air conditioning apparatus. Further, the present invention relates to compositions comprising lubricant and fire hazard-reducing agent and methods for reducing flammability of flammable refrigerant, for delivering a fire hazard-reducing agent to a refrigeration or air conditioning apparatus, and for replacing a non-flammable refrigerant with a flammable refrigerant.
US08758641B2 Refrigerant additive compositions containing perfluoropolyethers
The present invention relates to compositions and processes of using perfluoropolyether to maintain or improve the oil return, lubrication, cooling capacity, or energy efficiency of a refrigeration, air conditioning or heat transfer system.
US08758637B2 Apparatus and method of removing coating of line-shaped body using plasma
An apparatus of removing coatings of a line-shaped body of the invention includes a non-equilibrium atmospheric pressure plasma source with radicals controlled, having a plasma generating gas, a microwave, a micro gap; a line-shaped body holding portion for holding the line-shaped body within a range of 2 to 3 mm from an electrode to generate a plasma jet; and a moving stage for relatively moving the line-shaped body in the longitudinal direction thereof.
US08758635B2 Method for making thermoacoustic element
The present disclosure relates to a method for making a thermoacoustic element. In the method, a graphene film is arranged on a metal substrate. A nonmetal substrate is stacked with the graphene film located on the metal substrate to form a laminate structure. The graphene film is sandwiched between the nonmetal substrate and the metal substrate. The metal substrate is removed from the stacked structure. A number of through-holes are formed in the nonmetal substrate. The graphene film is exposed through the plurality of through-holes.
US08758629B2 Treatment of oil-contaminated solids
The disclosure pertains to systems and methods for removing hydrocarbon contaminants from a contaminated solid using an environmentally benign extractant and an oleophilic absorber, where the environmentally benign extractant and the oleophilic absorber are separate components.
US08758627B2 Twin tank water treatment method
Embodiments of the invention provide a twin tank water treatment system and method. The water treatment system includes first tank with a first set of sensors and a first resin bed, a second tank with a second set of sensors and a second resin bed, and a valve assembly with a flow meter and a controller in communication with the first set of sensors, the second set of sensors, and the flow meter. The method includes determining when the resin beds are exhausted based on input from the flow meter, the sensors, and a water hardness setting.
US08758624B2 Water treatment process, and membrane separation process and water treatment plant suitable therefor
A description is given of a multistage process for treating water, wherein a water stream is purified in a membrane separation stage and a downstream deionization unit having at least one concentrate chamber and at least one diluate chamber, wherein the water stream is separated in the membrane separation device into a concentrate stream and at least two permeate streams of different electrical conductivity, and wherein at least the permeate stream having the highest electrical conductivity is fed at least partially into the at least one concentrate chamber and at least the permeate stream having the lowest electrical conductivity is fed at least partially into the at least one diluate chamber of the downstream deionization unit. In addition, a membrane separation device is described which is constructed in such a manner that at least two permeate streams having different electrical conductivity can be generated therein, and also a water treatment plant, comprising at least one such membrane separation device and at least one deionization unit having at least one concentrate chamber and at least one diluate chamber.
US08758622B2 Simple gas scouring method and apparatus
A method of cleaning a membrane (6) in a membrane filtration system by flowing gas bubbles past the surfaces of the membrane (6) to scour accumulated solids therefrom. The method includes flowing a liquid past a supply of gas; creating a reduced pressure within the liquid flow to cause a flow of gas from the supply of gas (9) into the liquid flow and form gas bubbles therein and then flowing the liquid containing the gas bubbles past the surfaces of the membrane (6) to scour the surfaces thereof. Apparatus for performing the method is also disclosed.
US08758618B2 Method and a device for biologically treating a contaminated liquid feedstock including a dispersible and digestible organic liquid phase
The installation comprises three reaction vessels (100, 200, 300) in series, each containing an aqueous phase and a specific bacterial population. The vessels serve in succession to dissolve the liquid feedstock for treatment by enzymatic hydrolysis, then to biodegrade the resulting effluent by biological digestion, and finally to reduce the residual bacterial components by biological action. The vessels are mutually isolated by tangential filters (108, 208, 308) and by centrifugal separators (212, 312) for filtering the biomass from the reaction products. The result is a final liquid effluent (EFF/N) that is essentially non-organic, with the filtered biomass downstream constituting an ultimate organic waste (DU) of reduced volume.
US08758617B2 Wastewater processing method of hydrolysis-acidification enhanced by addition of zero-valent iron (ZVI)
The invention discloses a wastewater processing method of hydrolysis-acidification enhanced by addition of zero-valent iron (ZVI), including the following steps: 3˜6 ZVI-filling layers are settled in the middle of an anaerobic hydrolysis-acidification reactor. Excess sludge taken from sewage treatment plant using as seed sludge is added into this anaerobic hydrolysis-acidification reactor for startup and domestication. In the present invention, ZVI are added into this anaerobic hydrolysis-acidification reactor to accelerate organic matters degradation and produce more acetic acids, accompanied with higher COD removal obtained. ZVI can be protected from rust in this anaerobic biological environment due to the air isolation. Also, ZVI can enhance anaerobic hydrolysis of wastewater through reducing refractory pollutants involved in wastewaters. This novel method made the effluent from the hydrolysis-acidification reactor present less COD concentration and simpler substrate form, benefiting for the following anaerobic methanogenesis or aerobic treatment.
US08758615B2 Systems and methods for anaerobic digestion of biomaterials
Systems and methods for performing anaerobic digestion of biomaterials using a clarifier, a batch reactor, and/or a digester are disclosed. The clarifier performs pretreatment processing of biomaterial to improve anaerobic digestion. The batch reactor and/or the digester are coupled to the clarifier and are configured to digest the processed biomaterial. A control system for an anaerobic digestion process includes a flow control system, a temperature control system, and a totalization system. The flow control system controls the flow of biomaterial and the delivery of chemical agents to the biomaterial based on conductivity, temperature, pressure, and/or composition of the biomaterial. The temperature control system includes a heat source and heat exchangers that control the temperature of the biomaterial. The totalization system senses the volume of biomaterial in at least one stage of an anaerobic digestion process and a controller controls the flow control system based upon the sensed volume of biomaterial.
US08758614B2 Anaerobic membrane bioreactor for treating a waste stream
A waste stream having anaerobically biodegradable components is fed to an anaerobic reactor where the components react with microorganisms to biodegrade the components and produce biomass and biogas. Mixing occurs in select portions of the anaerobic reactor, particularly the bottom and top portions of the reactor. Relatively heavy solids settle to the bottom and are mixed with the mixed liquor while relatively light or fine solids float to the top portion of the anaerobic reactor where they are mixed with the mixed liquor. Mixed liquor is pumped from an intermediate portion of the anaerobic reactor to a membrane separation unit where the mixed liquor is separated into a permeate stream and a retentate stream that is concentrated with solids.
US08758609B2 Fitting coupler for planar fluid conduit
A fitting coupler is provided configured for coupling a planar fluid conduit and a fluidic device. The fluidic device comprises a cavity, a device conduit, and a mouth where the device conduit opens into the cavity. A contact pressure element is configured for sealingly pressing the planar fluid conduit to the mouth, so that a conduit opening of the planar fluid conduit opens into the mouth.
US08758608B2 Continuously flowing, inner circulatory, quasi-fluidized-bed reactor for resin ion exchange and adsorption
A continuously flowing, inner circulatory, quasi-fluidized-bed reactor for resin ion exchange and adsorption. The reactor comprises a main body casing, an inclined pipe separator, an outlet weir, an inlet pipe, an outlet pipe, a reducing fluidization tank, a guide plate, a resin regeneration tank, a resin discharge pipe, and a return pipe for regenerated resin and a distributing ejector. The reactor is particularly suitable for advanced treatment of supply water, wastewater, biochemical effluent and reclaimed water by using (magnetic) powder resin.
US08758603B2 Plasma purifying device and method of controlling plasma purifying device
A plasma purifying device is provided that is capable of recovering blood and plasma remaining within the plasma purifying device easily and without risk of coagulation, following completion of plasma purification therapy. The plasma purifying device has a control unit controls flow rates of the air pump and a plasma pump so that a pressure of the filtration side space of the plasma separator is higher than a pressure of the blood side space while delivering blood to the blood side space of the plasma separator by continuing to operate a blood pump without stopping following completion of plasma purification and then delivers plasma remaining in a filtration side space of a plasma separator to a blood side space of the plasma separator or to a plasma circuit by supplying air from an air pump.
US08758602B2 Method and apparatus for upgrading coal
A method of upgrading coal which comprises: pulverizing low-grade coal; mixing the pulverized low-grade coal with an oil to form a slurry; heating the slurry to or above the boiling point of water to vaporize the water contained in the low-grade coal and dehydrate the coal; compressing a vapor mixture of the steam resulting from the slurry heating and that part of the oil which has vaporized simultaneously and thereby elevating the temperature and pressure of the vapor mixture; and supplying the vapor mixture increased in temperature and pressure by the compression and utilizing this vapor mixture as a high-temperature heat source to heat the slurry. In the method, the vapor mixture before being compressed is brought into contact with an oil in a liquid state. This method is a process in which low-grade coal containing water in a large proportion and hence having a low calorific value is dewatered in an oil to thereby upgrade the coal to a high-calorie fuel for thermal power generation, wherein the vapor mixture to be supplied to a compressor can be purified.
US08758598B2 Catalyst comprising zeolite beta and its use in hydrocarbon conversion process
A hydrocarbon conversion catalyst comprising a modified beta zeolite, an amorphous inorganic oxide and a hydrogenation component wherein the said catalyst support has an NH3-AI of less than 3.5 and/or an IEC-AI of less than 3.7.
US08758592B2 Adhesive composition for use in an immunosensor
An adhesive composition for use in devices and methods for measuring a presence or a concentration of a particular component, such as an antigen, in a sample, such as blood, are provided. In one exemplary embodiment of an adhesive composition, the composition includes an adhesive, water, a poloxamer, and an anticoagulant. The adhesive can include particular properties, such as being hydrophilic, pressure-sensitive, heat-activated, and/or water soluble. The adhesive is particularly useful because it can help improve the flow of sample a device. For example, when the device is an immunosensor, the adhesive can help prevent the blood from clotting in chambers of the immunosensor. This results in a more efficient and accurate determination of the concentration of the sample. Methods of making the composition and device in which the composition can be used are provided, as are methods of using the same.
US08758591B2 Electrochemical nanocomposite biosensor system
The present invention relates to an electrode useful in electrochemical nanobiosensors for determining the presence or concentration of analytes in aqueous samples. In particular, the electrode comprises a biocatalyst or other bioreceptor entrapped in a conducting polymeric film deposited on a conducting material and a non-conducting or conducting coating. In particular embodiments, the conducting polymeric layer also comprises metallic nanoparticles. Electrochemical nanobiosensors containing the electrode, methods of making the electrode or sensor and methods of detecting analytes are other aspects of the invention.
US08758587B2 Analysis apparatus and analysis method
An analysis apparatus is provided with a storage tank, an injection nozzle, a syringe, a collection nozzle, a test sample tank, a microchip having two or more separation channels, detectors, a waste liquid tank, a controller, and a power supply. The collection nozzle collects a specimen which becomes a test sample from a test sample container housing the specimen, and transfers the specimen to the test sample tank. The separation channels separate characteristic components contained in the test sample. The injection nozzle is distanced from the collection nozzle and injects the test sample from the test sample tank into the separation channels. The detectors detect the separated characteristic components in the separation channels.
US08758584B2 Electrochemical sensors
Systems and methods are provided for detecting the presence of an analyte in a sample. A solid state electrochemical sensor can include a redox active moiety having an oxidation and/or reduction potential that is sensitive to the presence of an analyte immobilized over a surface of a working electrode. A redox active moiety having an oxidation and/or reduction potential that is insensitive to the presence of the analyte can be used for reference. Voltammetric measurements made using such systems can accurately determine the presence and/or concentration of the analyte in the sample. The solid state electrochemical sensor can be robust and not require calibration or re-calibration.
US08758583B2 Smart sensor ports and methods of using same
The present disclosure provides an orientation-nonspecific sensor port for use in analyte meters designed to detect and quantify analyte levels in a fluid sample along with methods of using the same. The present disclosure also provides compositions and methods for facilitating the correct insertion of a sensor into a corresponding analyte meter.
US08758582B2 Electrochemical test strip
An electrochemical test strip is formed from a first insulating substrate layer, a second substrate layer, and an intervening insulating spacer layer. An opening in the insulating spacer layer defines a test cell which is in contact with the inner surface of the first substrate on one side and the inner surface of the second substrate on the other side. The size of the test cell is determined by the area of substrate exposed and the thickness of the spacer layer. Working and counter electrodes appropriate for the analyte to be detected are disposed on the first insulating substrate in a location within the test cell. The working and counter electrodes are associated with conductive leads that allow The second substrate is conductive at least in a region facing the working and counter electrodes. No functional connection of this conductive surface of the second substrate to the meter is required. When a potential difference is applied between the working and counter electrodes, because of the presence of the conductive surface on the second substrate, the relevant diffusion length is not dependent on the distance between working and counter electrodes, but is instead dependent on the distance between the first and second substrates (i.e., on the thickness of the spacer layer). This means that shorter measurement times can be achieved without having to reduce the spacing of the working and counter electrodes.
US08758579B2 Chamber for physical vapour deposition and door for a physical vapour deposition chamber
A chamber for physical vapor deposition is provided. The chamber includes a housing, a door for opening and closing the housing, and a bearing for receiving a target, wherein the bearing is oriented in a first direction. Further, the chamber is adapted so that the target is at least partially removable from the chamber in the first direction. According to an embodiment, a chamber for physical vapor deposition is provided. The chamber is adapted for receiving at least one target and a substrate. The chamber includes a housing, a door, and at least one bearing for mounting the target, wherein the bearing is attached to the door.
US08758572B2 Method for the separation and concentration of isotopologues
The present invention is a novel method for removing tritium oxide contamination from a solution with water. The method captures the tritium oxide in a much smaller volume suitable for economical disposal. In so doing the original water is decontaminated of the tritium oxide and may be discharged.
US08758571B2 Method and arrangement for ameliorating the dewatering in a thin wire press
A method and apparatus for processing pulp is disclosed including opposed endless wires conveyed in the same direction and defining a web-forming space therebetween for dewatering the web, a pair of perforated dewatering tables supporting the endless wires for pressing the wires towards the web, the first perforated dewatering table ending upstream of the second perforated dewatering table, and a press roll downstream of the back end of the first perforated dewatering table and opposed to the back end of the second perforated dewatering table to form a nip between the press roll and the back end of the second perforated dewatering table, which has a profiled surface that interacts with the press roll to prolong the nip between the press roll and the back end of the second perforated dewatering table.