Document Document Title
US08729915B2 Current monitor for sensing the current in a current path and corresponding control device
A current monitor for sensing the current in a current path includes a resistive sensing element in a section of the current path and a current mirror circuit having a first semiconductor device and a second semiconductor device. Both semiconductor devices electrically interconnect with each other for copying the current in the second semiconductor device to the first semiconductor device. The first semiconductor device is electrically connected to an electric reference potential and to a current input side of the section via a resistive equivalence element in a first current branch. The second semiconductor device is electrically connected to the electric reference potential and to a current output side of the section in a second current branch. The current monitor further includes a constant current source for keeping the current in the second current branch independent from the potential difference between the potential of the current output side of the section and the reference potential.
US08729912B2 Displacement sensor
A linear capacitance displacement transducer (1) comprising first (2) and second (3) fixed capacitor plate and a dielectric structure (5) moveable longitudinally within a space (4) between the first (2) and second (3) capacitor plates, the dielectric structure (5) being operatively coupled to a moveable element (8). The capacitor plates and the dielectric material may be cylindrical and disposed coaxially and concentrically. The transducer (1) enables a displacement sensor that is capable of monitoring liquid levels in a syringe type drug reservoir (101) with sufficient sensitivity as to allow detection of erroneous drug delivery. The sensor is inexpensive to manufacture and provides reliable performance through robust design.
US08729908B2 Static noise margin monitoring circuit and method
A monitoring circuit and method, wherein a voltage waveform having a linear falling edge is applied to a first node of at least one test memory cell (e.g., a plurality of test memory cells connected in parallel). The input voltage at the first node is captured when the output voltage at a second node of the test memory cell(s) rises above a high reference voltage during the falling edge. Then, a difference is determined between the input voltage as captured and either (1) the output voltage at the second node, as captured when the input voltage at the first node falls below the first reference voltage during the falling edge, or (2) a low reference voltage. This difference is proportional to the static noise margin (SNM) of the test memory cell(s) such that any changes in the difference noted with repeated monitoring are indicative of corresponding changes in the SNM.
US08729907B2 Resistance-capacitance calibration circuit without current mismatch and method thereof
A resistor-capacitor (RC) calibration circuit includes: a current source, providing a current to a first node; a first switch, coupled between the first node and a second node; a second switch, coupled between the first node and a third node; a resistor, coupled between a reference terminal and the second node; a variable capacitor, coupled between the reference terminal and the third node; a third switch, coupled between the third node and the reference terminal; a comparator, comprising a first input coupled to the second node and a second input coupled to the third node; and a logic controller, coupled between an output of the comparator and the variable capacitor for outputting an adjusting signal according to an output signal of the comparator to adjust a capacitance of the variable capacitor.
US08729906B2 Monitoring partial discharge in high voltage systems
A method and device for monitoring partial discharges in high voltage electrical or power systems is provided. A low trigger level and a high trigger level electrical pulse amplitude levels are defined. At least one phase of the electrical system is monitored for an occurrence of a pulse within a defined minor time frame. A peak amplitude of a pulse occurring in the electrical system within the minor time frame is detected. It is determined if the detected peak amplitude of the pulse exceeds the lower and higher trigger levels. A pulse number is assigned to the pulse if the peak amplitude of the pulse exceeds the trigger levels. The pulse is captured if the pulse number associated with the pulse is less than a predetermined pulse number threshold in the minor time frame. The captured pulses are stored in a memory.
US08729903B2 Method for remote identification and characterization of hydrocarbon source rocks using seismic and electromagnetic geophysical data
Method for assessing hydrocarbon source rock potential of a subsurface region without well log information. The method uses surface electromagnetic (121) and seismic (122) survey data to obtain vertical profiles of resistivity and velocity (123), which are then analyzed in the same way as well log data are analyzed by the well known Delta Log R method (124).
US08729900B1 Locatable fiber optic cable
A communication cable, such as a fiber optic cable, can comprise a conductive tape that extends along the cable and that facilitates locating the cable from a remote location, for example when the cable is buried under ground. The tape can comprise a low resistance for transmitting a locate signal along the length of the cable that can be detected remotely by a detector without exposing the cable. The conductive tape can be circumferentially applied around the core of the cable under the cable's jacket. Thus, the conductive tape can be accessed without exposing the core. The cable can include one or more buffer tubes for housing optical fibers. The buffer tubes and/or the jacket can comprise an antioxidant for preventing degradation associated with contact with copper or other metal of the conductive tape.
US08729893B2 Nuclear magnetic resonance 1H and 13C multiphase flow measurements, estimating phase selected flow rates from velocity distributions, volume fractions, and mean velocity
A method and apparatus for estimating a flow rate of a phase of a multiphase fluid is disclosed. A first velocity distribution is obtained for a first set of nuclei in the fluid from a Nuclear Magnetic Resonance (NMR) signal received for the fluid in response to a first NMR excitation signal. A second velocity distribution is obtained for a second set of nuclei in the fluid from an NMR signal received for the fluid in response to a second NMR excitation signal. A velocity of the phase is estimated from the first velocity distribution and the second velocity distribution. The flow rate of the phase is estimated using the estimated velocity of the phase and an estimated volume fraction of the phase.
US08729892B2 Differential magnetic field sensor structure for orientation independent measurement
A differential magnetic field sensor that enables operation that is independent of sensor-to-target orientation is presented. The differential magnetic field sensor is provided with at least two differential channels. Each differential channel includes a pair of magnetic field sensing elements and has a respective sensing axis defined by those magnetic field sensing elements. The sensing axes are not aligned with respect to each other. One sensing axis is positioned relative to a reference axis of a target profile to define an orientation angle between the sensing axis and the reference axis. The differential magnetic field sensor includes circuitry to produce differential signals associated with the differential channels and use those differential signals to produce a single differential signal having an amplitude that is independent of the orientation angle.
US08729890B2 Magnetic angle and rotation speed sensor with continuous and discontinuous modes of operation based on rotation speed of a target object
A magnetic field sensor and a method used therein provide an output signal in angle units representative of an angle of rotation of a target of and also an output signal in speed units representative of a speed of rotation of the target object. A power control circuit can cycle a magnetic field sensor on and off in accordance with a sensed rotation speed of the object.
US08729888B2 Magnetic transducer configuration for magnet-based position sensors having improved geometry for more precise position detection
A magnetic transducer configuration may include a permanent magnet element magnetized in its longitudinal direction having a pole transition. The permanent magnet element has a cross section in the pole transition section, which is larger than the cross section of the permanent magnet element in an area outside of the pole transition section. A magnetic position sensor may include a magnetic field sensor array and magnetic transducer configuration. The magnetic field sensor array and the magnetic transducer configuration are situated displaceably in the longitudinal direction in a plane-parallel manner. The magnetic field sensor array has at least one magnetic field sensor lying in a path along which the permanent magnet element moves during displacement of the magnetic transducer configuration.
US08729876B2 Voltage regulator and related voltage regulating method thereof
A voltage regulator includes: a first comparator for comparing a first reference voltage with a feedback voltage to generate a first comparing result accordingly; a first transistor for controlling an output voltage at an output node in response to the first comparing result; a second transistor for adjusting the output voltage at the output node in response to a control signal; a feedback block, for providing the feedback voltage according to the output voltage; and a control block, for receiving the output voltage and providing the control signal according to the output voltage.
US08729871B2 Circuit and method for controlling the power supply of a consumer with current pulses having steep flanks
The present invention concerns a circuit for operating a consumer comprising a current source to provide a power supply for a consumer and a first switch connected in parallel with the consumer, in which through opening and closing of the first switch the power is transmitted to the consumer in the form of square wave current pulses. Here, a second switch is connected in parallel to the first switch and in series to the consumer which is opened and closed in anti-phase manner to the first switch, and a load with high load voltage is connected in parallel to the first switch and in series to the consumer. Furthermore, the present invention concerns a method for operating a circuit.
US08729866B2 Sulfide-based all-solid-state lithium secondary battery system
In an all-solid-state lithium secondary battery provided with a sulfide-based electrolyte-containing layer, the production of hydrogen sulfide is effectively inhibited without deteriorating battery characteristics. A battery system (100) is provided with: an all-solid-state lithium secondary battery (1) using a sulfide-based solid electrolyte material; and a reducing device (2, 3, 5) for reducing a charge-discharge amount of the all-solid-state lithium secondary battery if a temperature in an inside of the all-solid-state lithium secondary battery reaches a first threshold value.
US08729863B2 Battery and energy management circuit with temporal storage mode
An energy management circuit (100) for use with one or more rechargeable cells (201) is capable of prohibiting discharge in response to temporal or other inputs. In one embodiment, a control circuit (102) applies a control signal to a discharge control node (105) when a charging current is applied for less than a charging duration threshold. The control signal causes a discharge disconnect switch (202) to open. In another embodiment, the control circuit (102) applies the control signal to the discharge control node (105) after failing to detect a charging current for at least a non-charging duration threshold. Discharge can again be allowed by applying a charging current for at least a reset duration.
US08729862B2 Controlled regeneration of solid electrolyte interface for prolonged cycling of lithium batteries
A system implements a first charging method or a second charging method during one or more charge cycles of a battery. The first charging method includes a first voltage charging level and the second charging method includes a second voltage charging level that is higher than the first charging level.
US08729861B2 Power storage system
It is an object to provide a battery system whose life can be extended. A cell pack having at least one lithium secondary battery that uses a manganese-based cathode material and a control unit that controls charging and discharging of the cell pack are provided, and the control unit controls charging and discharging within a low-degradation voltage range that is set on the basis of a target cell degradation rate.
US08729854B2 Slot-type induction charger
A slot-type induction charger having light, thin, short and small characteristics is disclosed to include a power base holding therein a control module and a power-supplying coil module in a base member thereof for inducing an electric current, and an induction charging receiver set in the base member for receiving the induced electric current by electromagnetic induction from the power base for charging an electromagnetic device being connected to an electrical connector thereof. The power-supplying coil module and the power-receiving coil module each includes a magnetic conductor and a series of coils being alternatively and reversely wound around the magnetic conductor.
US08729853B2 Wireless charging device for portable electronic device
Disclosed is a wireless charging device for portable electronic device. The portable electronic device has a circuit device that includes a battery. The wireless charging device includes: a wireless transmission unit and a logic control unit, a step-up/step-down unit, first and second reverse current protectors, and at least a supercapacitor electrically connected between the circuit device and the wireless transmission unit. The first and second reverse current protectors function to prevent reverse current and to switch. The step-up/step-down unit controls step-up conversion in discharging and step-down conversion in charging. The logic control unit detects if a load exists on an opposite side of the wireless transmission unit and controls the operations of the step-up/step-down unit and the first and second reverse current protectors. The supercapacitor absorbs surge occurring in each charging operation to prevent accumulated damage caused by the charging operations.
US08729849B2 Motor control circuit and servo device provided with the same
When a servo device receives the frequency setting signal as a control signal through the receiver from the transmitter, it select the information in conformity with the received frequency setting signal among the driving frequency setting information as stored in advance. When the handling signal is input as the control signal by the transmitter, the servo device is configured to transform the difference data taken synchronously with the difference data timing signal from the pulse width comparison part into the selected driving frequency. The servo device is configured to generate the driving signal from the transformed difference data signal of the desired corresponding count value range, and to perform drive control the driving feature.
US08729847B2 Methods, systems and apparatus for generating current commands used to control operation of an electric machine
Embodiments of the present disclosure relate to methods, systems and apparatus for mapping torque to current to generate current commands used to control operation of an electric machine. Based on a DC input voltage, lookup tables (LUTs) are selected. Each of the selected LUTs includes a plurality (B) of first entries that correspond a particular input value of an angular rotation speed of the electric machine, and a set of coefficients are output from each of the selected LUTs that can be applied within a first polynomial function to generate a plurality of first polynomial functions each having a different sets of coefficients. A plurality of particular output values for a first current command are generated via the plurality of first polynomial functions. The particular output values for the first current command can be interpolated to generate a final output value for the first current command.
US08729845B2 Method and device for controlling an electric motor
A method and device for controlling an electric motor, in particular a machine tool drive, wherein during a sensorless open-loop control mode of operation of the electric motor the speed and the torque are determined from the motor current and the motor voltage, and the moment of inertia of the electric motor torque are determined from the determined motor current and the determined motor voltage, wherefrom then a control torque is determined, which is then associated with an open-loop torque control value and supplied as the torque setpoint value to a control element for setting the motor current and/or the motor voltage in the open-loop mode of operation. As long as the speed is below a minimum speed, the control element receives as input variable a control or pilot control torque generated from a predefined moment of inertia for a sensorless closed-loop control mode of operation of the electric motor.
US08729844B2 Power converter with asymmetric phase shift autotransformer for alternating current (AC) motor
An AC-AC power converter supplies AC power to an AC motor having a plurality of motor windings and a case connected to a ground. The AC-AC power converter architecture includes an asymmetric phase shift autotransformer/rectifier unit (ATRU) that converts an AC input to a DC output, wherein the asymmetric phase shift ATRU generates a common-mode AC voltage across the asymmetric phase shift ATRU. The common mode voltage is diverted to ground through motor case parasitic capacitance via a common-mode voltage pull-down circuit connected between each phase of the ATRU AC input and the ground.
US08729842B2 Supply architecture for inductive loads
Apparatus and associated systems and methods may relate to a process for supplying unidirectional current to a load, controlling a reverse electromotive force (REMF), capturing inductive energy from the load, and supplying the captured inductive energy to the load. In an illustrative example, an operating cycle may include a sequence of operations. First, inductive energy captured from the load on a previous cycle may be supplied to the load. Second, energy may be supplied to the load from an external power source. Third, a REMF voltage may be substantially controlled upon disconnecting the power source from the load. Fourth, the load current may be brought to zero by capturing the inductive energy for use on a subsequent cycle. In some embodiments, a single power stage may supply a DC inductive load, or a pair of power stages may be operated to supply bidirectional current to an AC load.
US08729840B2 Sensorless control unit for brushless DC motor
When a forced commutation mode ends, a switchover to a sensorless control mode is made. The sensorless control mode immediately after the switchover to the sensorless control mode is executed with a power source current maximum value set at a value higher than a rated current value of a motor. The sensorless control mode immediately after the switchover is executed only over a predetermined period of time, and, after a lapse of the predetermined period of time, a steady sensorless control mode is executed. In the steady sensorless control mode, the power source current maximum value is set at a value equal to the rated current value of the motor.
US08729839B2 Driving apparatus for sensorless fan motor
A BEMF detection circuit generates a rotation detection signal indicating a comparison result between electromotive force voltages VU through VW which occur at a terminal of respective multiple coils and an intermediate-point voltage VCOM. A rotor position detection circuit generates a rotor position detection signal indicating a stopped rotor position An internal start-up synchronization signal generating unit generates a predetermined-frequency forced synchronization signal. Upon receiving a fan motor start-up instruction, a driving signal synthesizing circuit generates a driving control signal based upon the rotor position detection signal. Thus, (1) when back electromotive force voltage occurs, a sensorless driving operation is started based upon the rotation detection signal; (2) when it does not occur, the driving control signal is generated based upon the forced synchronization signal. Subsequently, when it occurs, the sensorless driving operation is started based upon the rotation detection signal.
US08729838B2 Current control for an electric actuator
A controller for an electric actuator includes a reference model that generates position and speed reference signals in response to a position command signal and employs a feed forward model that accounts for dynamic loading of the electric actuator. The feed forward model receives the position and speed reference signals provided by the reference model, and in response generates feed forward signals that account for mechanical characteristics of the electric actuator.
US08729832B2 Programmable luminaire system
A system comprising a luminaire, a computerized device, and a docking member establishing electrical communication between the luminaire and the computerized device is disclosed. The luminaire may include an optic, a light source, a controller operably coupled to the light source, and an electrical connector configured to couple with the dock. The light source may be operable to emit light having a variety of characteristics, such as luminous intensity, color, color temperature, and any other characteristics of light. The controller may be programmable by a signal received from the computerized device via the dock.
US08729825B2 Active enclosure for computing device
A computing device is disclosed. The computing device includes a housing having an illuminable portion. The computing device also includes a light device disposed inside the housing. The light device is configured to illuminate the illuminable portion.
US08729819B2 Multi-output current-balancing circuit
The present invention relates to a multi-output current-balancing circuit, which in one embodiment can include: (i) a transformer having a primary winding and a plurality of secondary windings, where the primary winding receives an AC input current; (ii) a plurality of first and second rectifier circuits and a plurality of first current balancing components, where each of the first and second rectifier circuits and the first current balancing components is coupled to a corresponding secondary winding, where each the first current balancing component is configured for current balancing between each of the first and second rectifier circuits of the corresponding secondary winding; and (iii) at least one second current balancing component, where each second current balancing component is coupled to a pair of the second rectifier circuits that correspond to different secondary windings, where the second current balancing components are configured for current balancing between different the secondary windings.
US08729813B2 Switching power supply device and light-emitting diode lighting device
Implemented are a switching power supply device and a light-emitting diode lighting device in which a variation in load current can be suppressed against a wide range of variation in AC voltage. The configuration of the switching power supply device and the light-emitting diode lighting device includes: a rectifier unit which rectifies AC input voltage and outputs pulsating-current voltage; a power converting unit which receives the pulsating-current voltage and supplies a predetermined load current to a load; a current detecting unit which detects the load current; a drive control unit which controls the power converting unit to regulate the load current to a constant level; and an input voltage detecting unit which detects a variation in the AC input voltage. The drive control unit controls the power converting unit depending on the variation in the AC input voltage detected by the input voltage detecting unit.
US08729811B2 Dimming multiple lighting devices by alternating energy transfer from a magnetic storage element
A single magnetic storage element is used to provide power to multiple lighting devices, which may be strings of light-emitting diodes (LEDs) of different color. A switching circuit controls alternating application of energy among the multiple lighting devices and another switching circuit may charge the primary winding to different energy levels to control the intensity of the multiple lighting devices. In particular, the multiple lighting devices may be controlled to provide a desired color profile while dimming the lighting devices, while requiring only a single magnetic storage element for supplying energy to the lighting devices.
US08729807B2 Light emitting diode driving circuit
The present disclosure provides a light emitting diode driving circuit, comprising: a power conversion module having an input end, a control end and an output end, wherein the input end receives a voltage, the control end controls the regulation of the duty cycle signal therein according to a received control signal, and the output end outputs a DC voltage having a constant current and a variable voltage value; an overcurrent protection circuit having a switch module and a first resistor connected in series, wherein the overcurrent protection circuit and a LED load connected in series with each other are connected to the power conversion module, so as to turn off the electrical channel between the LED load and the power conversion module when overcurrent occurs; and an overvoltage protection circuit for outputting the control signal when overvoltage occurs and thereby protecting the LED load.
US08729806B2 RF-driven ion source with a back-streaming electron dump
A novel ion source is described having an improved lifetime. The ion source, in one embodiment, is a proton source, including an external RF antenna mounted to an RF window. To prevent backstreaming electrons formed in the beam column from striking the RF window, a back streaming electron dump is provided, which in one embodiment is formed of a cylindrical tube, open at one end to the ion source chamber and capped at its other end by a metal plug. The plug, maintained at the same electrical potential as the source, captures these backstreaming electrons, and thus prevents localized heating of the window, which due to said heating, might otherwise cause window damage.
US08729805B2 Plasma generator and discharge device and reactor using plasma generator
A plasma generator has a first member 2 containing a dielectric material, and an electrode group composed of a plurality of electrodes and including a first assembly 6 partially including a plurality of electrodes and a second assembly 7 partially including a plurality of electrodes. In accordance with an AC voltage, the first assembly 6 generates a plasma in a first space 23 contacting the first member 2. In accordance with a DC voltage, the second assembly 7 generates an electric field in a second space 24 contacting the first member 2 and communicating with the first space 23. At least one or more electrodes of a portion of the first assembly 6 and at least one or more electrodes of a portion of the second assembly 7 are provided on the surface of or in the inside of the first member 2.
US08729804B2 Switching module of adjusting a visual angle and related backlight system
A switching module capable of adjusting a visual angle is disclosed. The switching module includes an edge-type optical substrate, a light source disposed by a side of the edge-type optical substrate, and an optical modulating component disposed between the light source and the edge-type optical substrate. The edge-type optical substrate has an emitting surface. The light source includes a plurality of light units. Each light unit can emit a beam to the edge-type optical substrate according to a predetermined angle. The optical modulating component can modulate divergence of the beam emitted from the light unit, so that the beam can be guided out of the edge-type optical substrate via the emitting surface according to the predetermined angle.
US08729799B1 Low-workfunction photocathodes based on acetylide compounds
A low-workfunction photocathode includes a photoemissive material employed as a coating on the photocathode. The photoemissive material includes AnMC2, where A is a first metal element, the first element is an alkali metal, an alkali-earth element or the element Al; n is an integer that is 0, 1, 2, 3 or 4; M is a second metal element, the second metal element is a transition metal or a metal stand-in; and C2 is the acetylide ion C22−. The photoemissive material includes a crystalline structure or non-crystalline structure of rod-like or curvy 1-dimensional polymeric substructures with MC2 repeating units embedded in a matrix of A.
US08729798B2 Anti-reflective nanoporous silicon for efficient hydrogen production
Exemplary embodiments are disclosed of anti-reflective nanoporous silicon for efficient hydrogen production by photoelectrolysis of water. A nanoporous black Si is disclosed as an efficient photocathode for H2 production from water splitting half-reaction.
US08729793B2 Organic light-emitting display apparatus
An organic light-emitting display apparatus for selectively realizing circular polarization according to external light conditions, including a substrate; an organic light-emitting device on the substrate; a sealing member on the organic light-emitting device; a phase retardation layer on a surface of the substrate, the organic light-emitting device, or the sealing member; and a linear polarization layer on another surface of the substrate, the organic light-emitting device, or the sealing member, wherein the linear polarization layer is located to be closer to a source of external light than the phase retardation layer, and wherein the linear polarization layer comprises a photochromic material.
US08729792B2 Sign board
Provided is a high-quality sign board including an organic light emitting device (OLED) which can be easily adapted to various designs applied by users to the sign board. The sign board includes a substrate, a plurality of first conductive lines disposed on the substrate, a plurality of pixel electrodes electrically connected with the first conductive lines, an intermediate layer comprising a light emitting layer disposed on the pixel electrodes, and a face electrode disposed on the intermediate layer. In another embodiment, the sign board further includes a plurality of second conductive lines, each of which connects at least two of the first conductive lines to each other. In still another embodiment, the plurality of pixel electrodes includes a plurality of first pixel electrodes electrically connected with the first conductive lines, and a plurality of second pixel electrodes that are not electrically connected with the first conductive lines.
US08729789B2 Display apparatus
Provided is a display apparatus, which has both high light-emission efficiency and good display performance. The display apparatus includes multiple pixels, each of the multiple pixels including an organic light-emitting device including a first electrode, a light-emitting layer, and a second electrode, the multiple pixels including an optical unit for allowing a part of light emitted from the light-emitting layer to exit to outside while changing an exiting direction thereof, in which, in the multiple pixels including the optical unit, an optical distance between the light-emitting layer and the first electrode or an optical distance between the light-emitting layer and the second electrode is set to a predetermined value.
US08729777B2 Piezoelectric oscillator
A piezoelectric crystal unit includes a package including a concave portion; a piezoelectric element having a protruding electrode and disposed within the package; and an electrically conductive adhesive contained in the concave portion. The piezoelectric element is fixed to the package with the protruding electrode embedded in the concave portion of the package.
US08729774B2 Multiple arm smart material actuator with second stage
An actuator apparatus comprising a smart material device, a compensator, a movable supporting member, at least three mechanical webs, at least three actuating arms, and a second stage assembly is disclosed wherein the mechanical webs comprise a first resilient member attached to the compensator and a second resilient member attached to said movable supporting member. A piezoelectric or smart material device is affixed between the first mounting surface and the compensator. The actuating arms comprise a first actuating arm end attached to one mechanical web and a second actuating arm end attached to the second stage assembly. The second stage assembly comprises resilient strips having a first end attached to the actuating arm and a second end attached to a second stage attachment surface. Application of an electrical potential causes the smart material device to expand, thereby urging the movable supporting member away from the compensator and causing the first and second resilient members to flex. This in turn causes the actuating arms to move. The resilient strips urge the second stage attachment surface in a direction substantially parallel to the smart material device.
US08729772B1 Swept sideband PZT driver circuit
A swept sideband driver circuit has a boost converter followed by a buck converter obtaining near unity power factor. A full wave bridge powered from the buck converter circuit drives the PZT output load. The output of the buck converter circuit is controlled by a power level control circuit. The analog power level control circuit receives a sample of the output load current and a sample of the output load voltage from which it produces a product. The product signal is compared with manually adjusted pot signal. A difference signal results and used to adjust the output voltage of the buck converter circuit thereby increasing or decreasing the power to the load to drive the error signal to zero. A swept sideband modulation circuit modulates the frequency of the full wave bridge with a harmonic rich signal thereby imposing side bands on the voltage to the PZT load.
US08729767B2 Electric machine
An electric machine (1), particularly used as an electric motor, has a rotor (2) comprising a plurality of disks (4). A disk (4) of the rotor (2) is divided in a circumferential direction (5) into a plurality of disk sectors (6, 7, 8) between which magnetic pockets (9, 10) are designed. Furthermore, the disk (4) has an inner fastening collar (15) and connecting members (20, 23, 24) connecting the disk sectors (6, 7, 8) to the fastening collar (15). Such a connecting member (20) comprises a main web (21), a side arm (30) branching off the main rib (21) in the circumferential direction (5), and a side arm (31) branching off the main web (21) opposite to the circumferential direction (5). High mechanical stability of the disk (4) can thus be ensured, wherein magnetic flow losses are reduced.
US08729765B2 Field coil for an electric machine
A field coil segment for an electric machine including a rotor and a stator includes a first wire element having a first cross sectional area electrically connected in parallel with a second wire element having a second cross sectional area greater than the first cross sectional area.
US08729763B2 Rotor and IPM motor
Disclosed are a rotor and an IPM motor capable of avoiding concentration of flux on a corner area of a magnet on the stator side, leading to reduction in demagnetizing field and accordingly reduction in a required coercive force, and reduction in the usage amount of dysprosium or the like and accordingly reduction in manufacturing cost. In a slot bored in a rotor core of a rotor making up a motor, at least one of a slot face on a center side of the rotor core and a slot face facing this slot face is formed a protrusion or a concave groove and the magnet to be inserted in the slot includes at least one of a concave groove and a protrusion to be engaged with the protrusion or the concave groove of the slot face at a position corresponding to the protrusion or the concave groove formed in the slot. Then, these concave groove and protrusion are engaged to form an engagement part. This engagement part aligns and fixes the magnet in the rotor, and a flux barrier is formed between a lateral side face of the magnet and a slot face, the flux barrier having a same thickness as a thickness of the magnet.
US08729756B2 Canned motor pump and method for filling filling member into stator chamber thereof
A canned motor pump, wherein a motor stator is housed in a stator chamber that is a space between a tubular stator can for housing a motor rotor and a tubular stator band disposed coaxially with the stator can. The stator chamber is closed by annular end plates at the cylindrical ends between the stator can and the stator band. The stator chamber is filled with a filler. The filler is produced from spherical inorganic material particles filled into the stator chamber and resin for causing the particles to stick to each other. Consequently, the heat release performance of the stator of the canned motor pump is improved.
US08729755B2 Intermediate connection member, stator and motor
An intermediate connection member which electrically connects an output terminal of a bus bar installed inside a motor case with an external connection terminal located in a distance from the output terminal. The intermediate connection member preferably includes both of a terminal member which is connected to the output terminal and a connecting line which is connected to the external connection terminal. The connecting line is defined by binding a plurality of wire rods together.
US08729751B2 Heat transfer assembly for electric motor rotor
A motor driven assembly comprises a motor shaft, a rotor, a passage, and a corrugated fin heat transfer structure. The motor shaft is mounted for rotation about a rotational axis. The rotor is located radially about the shaft. The passage extends through the rotor alongside the motor shaft. The corrugated fin heat transfer structure is disposed within the passage radially aligned with the rotor.
US08729747B2 Method and apparatus for motional/vibrational energy harvesting via electromagnetic induction
A method and apparatus for motional/vibrational energy harvesting are disclosed. Embodiments of the subject invention utilize the non-resonant chaotic behavior of a free-rolling magnet to generate power. In one embodiment, the magnet can be spherical, cylindrical, or elliptical. The magnet can roll about a linear, cylindrical, helical, or cage-like track. The changing magnetic flux due to the magnet rolling about the track induces current in surrounding coils. The coils can be provided around the track using a continuous winding placement, segmented winding placement, or fractional winding placement. Multiple coil phases are also possible. For embodiments utilizing multiple magnets, spacers can be used to maintain a separation between magnets.
US08729746B2 Linear vibration device
The present invention provides a linear vibration device in which a PCB is coupled to a bracket having an extension piece protruding at a peripheral portion thereof to transfer an external electrical signal to a coil and a yoke of a stator is installed on an upper surface of the PCB to be coupled to the coil, in order to maximally generate an electromagnetic force in one direction. In addition, an upper plate and a lower plate are configured to concentrate a magnetic field of a magnet configured to create a magnetic field corresponding to an electromagnetic force of the yoke formed by the coil to one direction. Accordingly, a vibrating body includes a vibrator which is operated upward and downward in response to an electromagnetic force concentrated by the yoke, increasing vibration feelings due to the upward and downward movement thereof.
US08729742B2 Energy borrowing to reduce system voltage drop
An integrated circuit (IC) includes a first section having a sinking component sinking excessive current. A second section includes at least one sourcing component that, in operation, stores energy. A structure is provided to provide the stored energy from the at least one sourcing component to the sinking component, the stored energy being utilized by a load component included within the second section.
US08729739B2 Bi-directional circuit breaker
A circuit breaker comprising first and second JFETs, each comprising a gate, drain and source connection, the JFETs sources being operatively connected to each other to form a common-source connection and adapted to be connected to and operating to open an external circuit when the current flowing through the JFETs exceeds a predetermined threshold, the JFETs' gates, and common-source connection being operatively connected to a gate driver circuit which causes the JFETs to turn off when the predetermined threshold is exceeded; whereupon the current flows through the common-source connection into the second gate and into the gate driver circuit which causes the gate driver circuit to turn off the first and second JFETs and open the circuit breaker. Also claimed is a method of sensing an overloaded circuit comprising leading and trailing JFETs in a circuit that open the circuit and prevent current flow when a predetermined threshold is exceeded.
US08729736B2 Wireless power feeder and wireless power transmission system
Power is fed from a feeding coil L2 to a receiving coil L3 by magnetic resonance. An oscillator 202 alternately turns ON/OFF switching transistors Q1 and Q2 to cause AC current IS of drive frequency fo to flow in a transformer T2 primary coil Lb. The AC current IS causes AC current I1 to flow in an exciting coil L1 and causes AC current I2 to flow in the feeding coil L2.
US08729735B2 Wireless power feeder, wireless power receiver, and wireless power transmission system
Power is fed from a feeding coil L2 to a receiving coil L3 by magnetic resonance. A VCO 202 alternately turns ON/OFF switching transistors Q1 and Q2 at a drive frequency fo, whereby AC power is fed to the feeding coil L2, and then the AC power is fed from the feeding coil L2 to the receiving coil L3. A phase detection circuit 114 detects a phase difference between the current phase and voltage phase, and the VCO 202 adjusts the drive frequency fo such that the phase difference becomes zero. When load voltage is changed, the detected current phase value is adjusted with the result that the drive frequency fo is adjusted.
US08729726B2 Petroleum-alternative power plant
The present disclosure includes a petroleum-alternative power plant system harvesting wind, solar, and thermal energies. The system may include at least one two-wind-turbine power tower building where the outside surface of the building is divided into a number of sections. Each section forms a funnel- shaped duct to guide and accelerate the wind streams toward the vanes of the first wind turbine; then wind streams accelerated further and guided toward the vanes of a second wind turbine. The system may also include solar receptors, solar tower, and thermal receptors to harvest more energy. A management control subsystem is provided to combine electricity, and selectively delivering electricity to any electric load, a non-fossil fuel production subsystem, and the power grid.
US08729722B2 Wind turbine and method for monitoring the gap length between a rotor and a stator of the wind turbine generator
Wind turbine comprising a generator section with a generator rotor and a generator stator. A first air gap is defined between a first surface of the generator rotor and the stator, and magnets and electro conductive windings are provided at opposite sides of the first air gap to create a magnetic field over the first air gap during operation. The wind turbine comprises distance measurement means arranged to measure the radial length of a second air gap defined between a second surface of the generator rotor and a stationary part of the generator section. The second air gap is located at a radial distance from the first air gap at a position where there is no interference of a magnetic field generated by the magnets over the first air gap, and the length of the second air gap corresponds directly to the length of the first air gap. This enables accurate measurement and monitoring of the air gap length. A method for monitoring the gap length between a rotor and a stator of a wind turbine generator is also disclosed.
US08729720B1 Efficient energy producing system
A system for generating output energy with minimal input energy is disclosed. The system's components include a crankshaft, a speed multiplier, a first electrical generator, a transformer, and a fluid power circuit. The speed multiplier is coupled to the crankshaft by way of a low-speed shaft. The first electric generator is coupled to the speed multiplier by way of a high-speed shaft. The transformer is configured to receive electricity produced by the first electrical generator. The transformers output electricity is used to power the fluid power circuit. The fluid power circuit is reciprocally coupled to the crankshaft, such that operation of the fluid power circuit sets the crankshaft in motion. The fluid power circuit may be an oleo-hydraulic circuit or a pneumatic circuit. A rotor and fluid-propelled turbine may also be affixed to the crankshaft in order to set the crankshaft into motion.
US08729718B2 Thermomagnetic generator
A thermomagnetic generator is provided, including a switch valve, a plurality of magnetic circuit units, a coil, and a plurality of inlet pipes connecting the magnetic circuit units to the switch valve. Each of the magnetic circuit units includes a magneto-caloric member. The switch valve repeatedly and alternatively switches at a predetermined frequency to guide hot and cold fluids to the magnetic circuit units, such that the magneto-caloric members are magnetized and demagnetized, respectively, by the cold and hot fluids. The coil is coupled to at least one of the magnetic circuit units for obtaining an induced voltage.
US08729717B2 Turbocompound free piston linear alternator
A free piston linear alternator including a pair of pistons, each piston axially opposed from the other and generating electric current when linearly translating within the cylinder, a combustion chamber disposed between the pistons, a return mechanism configured to return the pistons to respective first positions from respective second positions after combustion; and an exhaust system fluidly coupled to the combustion chamber and including a power turbine transforming exhaust gas feedstream pressure into a mechanical output.
US08729716B2 Alignment accuracy mark
An alignment accuracy (AA) mark is described, including N (N≧3) pattern sets defined by N exposure steps respectively. The N exposure steps are performed also to a device area disposed on a wafer together with the AA mark. The i-th (i=1, 2 . . . N−1) pattern set surrounds the (i+1)-th pattern set. Each pattern set includes a 1st set of x-directional linear patterns, a 2nd set of x-directional linear patterns arranged opposite to the 1st set of x-directional linear patterns in the y-direction, a 1st set of y-directional linear patterns, and a 2nd set of y-directional linear patterns arranged opposite to the 1st set of y-directional linear patterns in the x-direction, wherein each set of x- or y-directional linear patterns include at least three separate parallel linear patterns.
US08729714B1 Flip-chip wafer level package and methods thereof
An electronic package includes a flip-chip component having a first die coupled to a flip-chip substrate, second die stacked on the first die, an encapsulation compound formed around the first die and the second die, a set of through encapsulant vias (TEVs) providing a set of electrical connections from a first side of the electronic package to a second side of the electronic package through the encapsulation compound to the flip-chip substrate, and a redistribution layer electrically connecting a set of contacts on the second die to the set of TEVs on the first side of the electronic package.
US08729711B2 Semiconductor device
A semiconductor device includes a semiconductor substrate having a first surface being an element formation surface, and a second surface opposite to the first surface; a through-hole formed to penetrate the semiconductor substrate from the first surface to the second surface; an insulating film formed on an inner wall of the through-hole; a barrier film formed on the inner wall of the through-hole with the insulating film interposed therebetween; and a conductive portion formed to fill the through-hole provided with the insulating film and the barrier film. A gettering site is formed in a portion of the semiconductor substrate around the through-hole at least near a side of the first surface.
US08729709B2 Semiconductor device
This invention provides a multi-pin semiconductor device as a low-cost flip-chip BGA. In the flip-chip BGA, a plurality of signal bonding electrodes in a peripheral area of the upper surface of a multilayer wiring substrate are separated into inner and outer ones and a plurality of signal through holes coupled to a plurality of signal wirings drawn inside are located between a plurality of rows of signal bonding electrodes and a central region where a plurality of bonding electrodes for core power supply are located so that the chip pad pitch can be decreased and the cost of the BGA can be reduced without an increase in the number of layers in the multilayer wiring substrate.
US08729706B2 Semiconductor structure having a permeable hard mask layer sealing an air gap
A method for forming a semiconductor structure includes forming a sacrificial layer over a substrate. A first dielectric layer is formed over the sacrificial layer. A plurality of conductive structures are formed within the sacrificial layer and the first dielectric layer. The sacrificial layer is treated through the first dielectric layer, at least partially removing the sacrificial layer and forming at least one air gap between two of the conductive structures. A surface of the first dielectric layer is treated, forming a second dielectric layer over the first dielectric layer, after the formation of the air gap. A third dielectric layer is formed over the second dielectric layer. At least one opening is formed within the third dielectric layer such that the second dielectric layer substantially protects the first dielectric layer from damage by the step of forming the opening.
US08729702B1 Copper seed layer for an interconnect structure having a doping concentration level gradient
A trench is opened in a dielectric layer. The trench is then lined with a barrier layer and a metal seed layer. The metal seed layer is non-uniformly doped and exhibits a vertical doping gradient varying as a function of trench depth. The lined trench is then filled with a metal fill material. A dielectric cap layer is then deposited over the metal filled trench. Dopant from the non-uniformly doped metal seed layer is then migrated to an interface between the metal filled trench and the dielectric cap layer to form a self-aligned metal cap.
US08729701B2 Copper diffusion barrier
The invention concerns a method of forming a copper portion surrounded by an insulating material in an integrated circuit structure, the insulating material being a first oxide, the method having steps including forming a composite material over a region of the insulating material where the copper portion is to be formed, the composite material having first and second materials, annealing such that the second material reacts with the insulating material to form a second oxide that provides a diffusion barrier to copper; and depositing a copper layer over the composite material by electrochemical deposition to form the copper portion.
US08729698B2 Method of manufacturing semiconductor device, semiconductor device and multilayer wafer structure
Grooves are formed on the front surfaces of first and second semiconductor wafers each including an aggregate of a plurality of semiconductor chips. The grooves each extend on a dicing line set between the semiconductor chips and to have a larger width than the dicing line. Thereafter the first and second semiconductor wafers are arranged so that the front surfaces thereof are opposed to each other, and the space between the first semiconductor wafer and the second semiconductor wafer is sealed with underfill. Thereafter the rear surfaces of the first and second semiconductor wafers are polished until at least the grooves are exposed, and a structure including the first and second semiconductor wafers and the underfill is cut on the dicing line.
US08729696B2 Testing device for laser diode
In a testing method for an LD, an LD die is held. Then, electric current increasing with a fixed increment and having a sequence of current values is supplied to the LD die to drive the LD die to emit light and a sequence of voltage values across the LD die and corresponding to the sequence of current values, respectively, is metered. A sequence of power values corresponding to the sequence of current values, respectively, is also metered. Next, an electro-optical property of the LD die is determined according to the sequence of current values, the sequence of voltage values, and the sequence of power values. Finally, if the LD die is determined to be qualified based upon the electro-optical property of the LD die, the LD die is packaged into the LD.
US08729694B2 Semiconductor device and method of forming conductive vias with trench in saw street
A semiconductor wafer has a plurality of semiconductor die separated by a peripheral region. A trench is formed in the peripheral region of the wafer. A via is formed on the die. The trench extends to and is continuous with the via. A first conductive layer is deposited in the trench and via to form conductive TSV. The first conductive layer is conformally applied or completely fills the trench and via. The trench has a larger area than the vias which accelerates formation of the first conductive layer. A second conductive layer is deposited over a front surface of the die. The second conductive layer is electrically connected to the first conductive layer. The first and second conductive layers can be formed simultaneously. A portion of a back surface of the wafer is removed to expose the first conductive layer. The die can be stacked and electrically interconnected through the TSVs.
US08729692B2 Power module package
Disclosed herein is a power module package including: a first heat dissipation plate including a first flow path, a second flow path, and a third flow path which are sequentially formed, the first flow path and the third flow path being formed to have a step therebetween; and a second heat dissipation plate formed under the first heat dissipation plate, having one face and the other face, having a semiconductor device mounting groove formed in the one face thereof, and including a fourth flow path having one end connected to the second flow path and the other end connected to the third flow path, wherein a cooling material introduced through the first flow path is distributed to the third flow path and the fourth flow path based on the second flow path.
US08729691B2 Distributed semiconductor device methods, apparatus, and systems
Some embodiments include a device having a number of memory cells and associated circuitry for accessing the memory cells. The memory cells of the device may be formed in one or more memory cell dice. The associated circuitry of the device may also be formed in one or more dice, optionally separated from the memory cell dice.
US08729690B2 Assembly having stacked die mounted on substrate
Metal rerouting interconnects at one or more sides of a die or multiple die segments can form edge bonding pads for electrical connection. Insulation can be applied to surfaces of the die or multiple die segments after optional thinning and singulation, and openings can be made in the insulation to the electrical connection pads. After being placed atop one another in a stack, vertically adjacent die or die segments can be electrically interconnected using a flexible bond wire or bond ribbon attached to an electrical connection pad exposed within such opening, the bond wire or ribbon protruding horizontally, and an electrically conductive polymer, or epoxy, filaments or lines can be applied to the stack.
US08729689B2 Stacked semiconductor package
Provided is a stacked semiconductor package. The stacked semiconductor package of the present invention comprises: a substrate unit, which includes a connection substrate electrically connecting a first substrate having a contact pad and a second substrate having a contact pad; a first chip laminate at which a plurality of first semiconductor chips are stacked in multi-steps on the first substrate; a second chip laminate at which a plurality of second semiconductor chips are stacked in multi-steps on the second substrate; a first conductive wire which electrically connects a first bonding pad of the first semiconductor chip and the contact pad of the first substrate, a second conductive wire which electrically connects a second bonding pad of the second semiconductor chip and the contact pad of the second substrate, and a bonding unit which has a contact adhesive layer having a certain thickness, which is disposed between the first semiconductor chip in the top layer of the first chip laminate and the second semiconductor chip in the top layer of the second chip laminate, and which vertically stacks and bonds the first chip laminate and the second chip laminate.
US08729688B2 Stacked seminconductor package
Provided is a stacked semiconductor package. The stacked semiconductor package of the present invention comprises: a substrate including at least one contact pad; an external chip laminate which includes a plurality of semiconductor chips mounted on the substrate, and which is stacked in multi-steps such that the ends at one side of the plurality of semiconductor chips alternately protrude in opposite directions to expose bonding pads which are formed on the up-face surface; at least one internal chip which is disposed in a mounting space formed between the external chip laminate and substrate so as to be electrically connected to the substrate; and a conductive wire electrically connecting the bonding pad of the semiconductor chip and the contact pad of the substrate.
US08729687B2 Stackable integrated circuit package system
A stacked integrated circuit package-in-package system is provided including forming a first external interconnect; mounting a first integrated circuit die below the first external interconnect; stacking a second integrated circuit die over the first integrated circuit die in an offset configuration not over the first external interconnect; connecting the first integrated circuit die with the first external interconnect; and encapsulating the second integrated circuit die with the first external interconnect and the first integrated circuit die partially exposed.
US08729684B2 Interposer chip, multi-chip package including the interposer chip, and method of manufacturing the same
An interposer chip may include a substrate, a plurality of upper terminals, a plurality of lower terminals, a first conductive pattern that electrically connects the first upper terminal to a first set of one or more lower terminals, a second conductive pattern that electrically connects the second upper terminal to a second set of one or more lower terminals and a cut test pattern disposed between the first conductive pattern and the second conductive pattern, the test pattern used for testing electrical characteristics of the first conductive pattern and the second conductive pattern.
US08729682B1 Conformal shield on punch QFN semiconductor package
In accordance with the present invention, there is provided a punch quad flat no leads (QFN) semiconductor package including a leadframe wherein the leads of the leadframe are selectively half-etched so that only one or more prescribed leads may be electrically connected to a conformal shield applied to the package body of the semiconductor package. The conformal shield may be electrically connected to the exposed lead(s) alone, or in combination with one or more tie bars of the leadframe. In one embodiment, outer end portions of the top surfaces of the leads of the semiconductor package are alternately exposed and non-exposed, with the non-exposed leads including a top side half-etch which causes the same to be effectively covered by the package body of the semiconductor package.
US08729681B2 Package structure and LED package structure
A package structure includes a base unit, a pin unit and a housing unit. The base unit has a carrier member and a through hole penetrating through the carrier member, and at least one annular structure is formed in the through hole. The pin unit has a plurality of conductive pins disposed beside the carrier member. The housing unit has an annular housing encircling the carrier member to envelop one part thereof and connecting to the pin unit, and the annular housing is partially filled into the through hole to cover the annular structure. Therefore, the instant disclosure can increase the bonding force between the carrier member and the annular housing and retard external moisture to permeate through slits between the carrier member and the annular housing to intrude into the chip-mounting region, thus the reliability and the usage life are increased.
US08729676B2 Silicon epitaxial wafer and method for manufacturing the same
The present invention includes a method for manufacturing a silicon epitaxial wafer having a silicon homoepitaxial layer formed on a surface of a silicon single crystal wafer, including the steps of: preparing the silicon single crystal wafer such that a plane orientation of the silicon single crystal wafer is tilted at an angle in the range from 0.1° to 8° in a <112> direction from a {110} plane; and growing the silicon homoepitaxial layer on the prepared silicon single crystal wafer. According to the present invention, a silicon epitaxial wafer using the {110} substrate with improved surface quality, such as Haze and surface roughness and a method for manufacturing the silicon epitaxial wafer are provided.
US08729672B2 Method for growing group 13 nitride crystal and group 13 nitride crystal
To grow a gallium nitride crystal, a seed-crystal substrate is first immersed in a melt mixture containing gallium and sodium. Then, a gallium nitride crystal is grown on the seed-crystal substrate under heating the melt mixture in a pressurized atmosphere containing nitrogen gas and not containing oxygen. At this time, the gallium nitride crystal is grown on the seed-crystal substrate under a first stirring condition of stirring the melt mixture, the first stirring condition being set for providing a rough growth surface, and the gallium nitride crystal is subsequently grown on the seed-crystal substrate under a second stirring condition of stirring the melt mixture, the second stirring condition being set for providing a smooth growth surface.
US08729669B2 Bipolar transistor and method for manufacturing the same
A method for manufacturing a bipolar transistor includes forming a first epitaxial layer on a semiconductor substrate, forming a second epitaxial layer on the first epitaxial layer, forming an oxide layer on the second epitaxial layer, etching the oxide layer to form an opening in which the second epitaxial layer is exposed, and forming a third epitaxial layer in the opening. The first and third epitaxial layers have a first-type conductivity, and the second epitaxial layer has a second-type conductivity.
US08729668B2 Adjustable resistor
An adjustable resistor formed on a first insulating layer of a substrate, including: a first polysilicon layer covered with a second insulating layer of a first thickness, except in a region where the first polysilicon layer is covered with a thin insulator layer of a second thickness smaller than the first thickness; a second polysilicon layer covering the second insulating layer and the thin insulator layer; on each side of the second insulating layer and at a distance from it, a first and a second conductive vias providing access to the terminals of the resistor on the first polysilicon layer; and a third conductive via providing access to a contacting area on the second polysilicon layer.
US08729667B2 Non-volatile memory device and method of manufacturing the same
According to one embodiment, a second electrode layer is formed on first structures where a first electrode layer and a first memory cell layer sequentially stacked above a substrate are patterned in a line-and-space shape extending in a first direction and a first interlayer insulating film embedded between the first structures. Etching is performed from the second electrode layer to a predetermined position in an inner portion of the first memory cell layer by using a first mask layer having a line-and-space pattern extending in a second direction, so that a first trench is formed. A first modifying film is formed on a side surface of the first trench, anisotropic etching is performed on the first memory cell layer by using the first mask layer, and after that, isotropic etching is performed.
US08729666B2 Ultra-low voltage coefficient capacitors
A capacitor has first and second conducting plates and a dielectric region between the plates, wherein the dielectric region comprises two dielectric materials for each of which the variation of capacitance with voltage can be approximated by a polynomial having a linear coefficient and a quadratic coefficient, and wherein the quadratic coefficients of the two dielectric materials are of opposite sign. The capacitor comprises for example a first capacitor (42) and a second capacitor (44) that one connected in an anti-parallel manner. The insulating layer (18) of the first capacitor comprises silicon nitride and the insulating layer (16) of the second capacitor comprises silicon dioxide.
US08729660B2 MEMS integrated chip with cross-area interconnection
The present invention discloses a MEMS (Micro-Electro-Mechanical System) integrated chip with cross-area interconnection, comprising: a substrate; a MEMS device area on the substrate; a microelectronic device area on the substrate; a guard ring separating the MEMS device area and the microelectronic device area; and a conductive layer on the surface of the substrate below the guard ring, or a well in the substrate below the guard ring, as a cross-area interconnection electrically connecting the MEMS device area and the microelectronic device area.
US08729655B2 Etching narrow, tall dielectric isolation structures from a dielectric layer
Methods of forming isolation structures are disclosed. A method of forming isolation structures for an image sensor array of one aspect may include forming a dielectric layer over a semiconductor substrate. Narrow, tall dielectric isolation structures may be formed from the dielectric layer. The narrow, tall dielectric isolation structures may have a width that is no more than 0.3 micrometers and a height that is at least 1.5 micrometers. A semiconductor material may be epitaxially grown around the narrow, tall dielectric isolation structures. Other methods and apparatus are also disclosed.
US08729653B2 Integrated die-level cameras and methods of manufacturing the same
An integrated die-level camera system and method of making the camera system include a first die-level camera formed at least partially in a die. A second die level camera is also formed at least partially in the die. Baffling is formed to block stray light between the first and second die-level cameras.
US08729648B2 Magnetic body device and manufacturing method thereof
A magnetic body device has a stacked structure comprising an underlying layer, a magnetic body layer, and a cap layer. The material for the underlying layer is different from that for the cap layer. The magnetic body layer has a free magnetization region having perpendicular magnetic anisotropy and a first characteristic change region and a second characteristic change region situated on both sides of the free magnetization region in a first in-plane direction. The perpendicular magnetic anisotropy of the first characteristic change region and the second characteristic change region is at a level lower than that of the free magnetization region. An external magnetic field containing a component in the first in-plane direction is applied to the free magnetization region. Further, a current in the first in-plane direction is supplied to the free magnetization region.
US08729644B2 Programmable III-nitride semiconductor device
A III-nitride semiconductor device which includes a charged gate insulation body.
US08729643B2 Cross-coupled transistor circuit including offset inner gate contacts
A first conductive gate level feature forms a gate electrode of a first transistor of a first transistor type. A second conductive gate level feature forms a gate electrode of a first transistor of a second transistor type. A third conductive gate level feature forms a gate electrode of a second transistor of the first transistor type. A fourth conductive gate level feature forms a gate electrode of a second transistor of the second transistor type. A first contact connects to the first conductive gate level feature over an inner non-diffusion region. The first and fourth conductive gate level features are electrically connected through the first contact. A second contact connects to the third conductive gate level feature over the inner non-diffusion region and is offset from the first contact. The third and second conductive gate level features are electrically connected through the second contact.
US08729642B2 Semiconductor device comprising a gate electrode having an opening
A semiconductor device comprises an active region formed in a semiconductor substrate and a gate electrode formed on the active region via a gate insulating film formed on a surface of the active region. A peripheral portion of the gate electrode and a peripheral portion of the active region overlap each other at a position where the active region is not divided by the gate electrode when viewed in plan view, thus forming an overlap region.
US08729641B2 Semiconductor device
A semiconductor device includes a first, second, and third MIS transistors of a first conductivity type respectively including a first, second, and third gate electrodes on a first, second, and third active regions of a semiconductor substrate with a first, second, and third gate insulating films interposed therebetween. The first gate insulating film is formed of a first silicon oxide film and a first high-k insulating film on the first silicon oxide film. The second gate insulating film is formed of a second silicon oxide film and a second high-k insulating film on the second silicon oxide film. The third gate insulating film is formed of a third silicon oxide film and a third high-k insulating film on the third silicon oxide film. The second silicon oxide film has a same thickness as the first silicon oxide film, and a greater thickness than the third silicon oxide film.
US08729640B2 Method and structure for radiation hardening a semiconductor device
Semiconductor devices can be fabricated using conventional designs and process but including specialized structures to reduce or eliminate detrimental effects caused by various forms of radiation. Such semiconductor devices can include the one or more parasitic isolation devices and/or buried guard ring structures disclosed in the present application. The introduction of design and/or process steps to accommodate these novel structures is compatible with conventional CMOS fabrication processes, and can therefore be accomplished at relatively low cost and with relative simplicity.
US08729639B2 Semiconductor device and method for producing the same
According to one embodiment, a semiconductor device includes a gate electrode formed on a substrate with a gate insulation film interposed therebetween, and a source region of a first conductivity type and a drain region of a second conductivity type reverse to the first conductivity type, which are formed so as to hold the gate electrode therebetween within the substrate. The work function of a first region on the source region side within the gate electrode is shifted toward the first conductivity type as compared to the work function of a second region on the drain region side within the gate electrode.
US08729637B2 Work function adjustment by carbon implant in semiconductor devices including gate structure
A device including a p-type semiconductor device and an n-type semiconductor device on a semiconductor substrate. The n-type semiconductor device includes a gate structure having a high-k gate dielectric. A carbon dopant in a concentration ranging from 1×1016 atoms/cm3 to 1×1021 atoms/cm3 is present at an interface between the high-k gate dielectric of the gate structure for the n-type semiconductor device and the semiconductor substrate. Methods of forming the aforementioned device are also disclosed.
US08729636B2 Integrated circuit and method for manufacturing an integrated circuit
Integrated circuit comprising a substrate carrying at least one transistor comprising an alternating grid (1) of source and drain regions (D, S) separated by a grid (14) of gate regions, e.g. a checkerboard pattern of source and drain regions. The source regions (S) are vertically connected to a first metal layer and the drain regions (D) are vertically connected to a second metal layer. At least one of the first metal layer and the second metal layer comprises a metal grid (30, 40) of a plurality of interconnected metal portions (32, 42) arranged such that said grid comprises a plurality of gaps (34, 44) for connecting respective substrate portions to a further metal layer. Method for manufacturing such an integrated circuit.
US08729632B2 Semiconductor structure with low resistance of substrate and low power consumption
A semiconductor structure comprising a semiconductor unit, a first conductive structure, a first conductive plug, and a second conductive structure is provided. The semiconductor unit has a substrate on a first side of the semiconductor unit. The substrate has at least a hole. The first conductive plug is in the hole and the hole may be full of the conductive plug. The first conductive structure is on the surface of the semiconductor unit. The surface is at the first side of the semiconductor unit. The second conductive structure is on a surface at a second side of the substrate of the semiconductor unit.
US08729630B1 Double diffused metal oxide semiconductor device and manufacturing method thereof
The present invention discloses a double diffused metal oxide semiconductor (DMOS) device and a manufacturing method thereof. The DMOS device includes: an isolation structure for defining device regions; a gate with a ring-shaped structure; a drain located outside the ring; and a lightly doped drain, a source, and a body electrode located inside the ring. To increase the sub-threshold voltage at the corners of the gate, the corners are located completely on the isolation structure, or the lightly doped drain is apart from the corners by a predetermined distance.
US08729629B2 Enhanced HVPMOS
A p-channel LDMOS device with a controlled n-type buried layer (NBL) is disclosed. A Shallow Trench Isolation (STI) oxidation is defined, partially or totally covering the drift region length. The NBL layer, which can be defined with the p-well mask, connects to the n-well diffusion, thus providing an evacuation path for electrons generated by impact ionization. High immunity to the Kirk effect is also achieved, resulting in a significantly improved safe-operating-area (SOA). The addition of the NBL deep inside the drift region supports a space-charge depletion region which increases the RESURF effectiveness, thus improving BV. An optimum NBL implanted dose can be set to ensure fully compensated charge balance among n and p doping in the drift region (charge balance conditions). The p-well implanted dose can be further increased to maintain a charge balance, which leads to an Rdson reduction.
US08729621B2 Memory devices comprising word line structures, at least one select gate structure, and a plurality of doped regions
Disclosed is a method of forming memory devices employing halogen ion implantation and diffusion processes. In one illustrative embodiment, the method includes forming a plurality of word line structures above a semiconducting substrate, each of the word line structures comprising a gate insulation layer, performing an LDD ion implantation process to form LDD doped regions in the substrate between the word line structures, performing a halogen ion implantation process to implant atoms of halogen into the semiconducting substrate between the word line structures, and performing at least one anneal process to cause at least some of the atoms of halogen to diffuse into the gate insulation layers on adjacent word line structures.
US08729620B2 Nonvolatile semiconductor memory device
It is an object to provide a nonvolatile semiconductor memory device having excellent writing property and charge-retention property. A semiconductor layer including a channel forming region between a pair of impurity regions which are formed to be apart from each other is provided. In an upper layer portion thereof, a first insulating layer, a floating gate, a second insulating layer, and a control gate are provided. The floating gate has at least a two-layer structure, and a first layer in contact with the first insulating layer preferably has a band gap smaller than that of the semiconductor layer. Furthermore, by setting an energy level at the bottom of the conduction band of the floating gate lower than that of the channel forming region of the semiconductor layer, injectability of carriers and a charge-retention property can be improved.
US08729619B2 Semiconductor device and fabricating method of the same
Openings are formed by lithography and subsequent dry etching at the portions of a first protective film which correspond to connecting holes of second plugs which will be described later, namely at the portions thereof which align with first plugs, wherein the openings have a diameter greater than that of connecting holes by about 0.4 μm.
US08729618B2 Semiconductor device and method for manufacturing the same
A method for manufacturing a semiconductor device comprises forming a first layer on an impurity diffusion region in a semiconductor substrate by a selective epitaxial growth method, forming a second layer on the first layer by the selective epitaxial growth method, forming a contact hole penetrating an interlayer insulating film in a thickness direction thereof and reaching the second layer, and filling a conductive material into the contact hole to form a contact plug including the first and second layers and the conductive material.
US08729603B2 GaN-based semiconductor element
A GaN-based semiconductor element includes a substrate, a buffer layer formed on the substrate, including an electrically conductive portion, an epitaxial layer formed on the buffer layer, and a metal structure in ohmic contact with the electrically conductive portion of the buffer layer for controlling an electric potential of the buffer layer.
US08729601B2 Nanotube semiconductor devices
Semiconductor devices are formed using a thin epitaxial layer (nanotube) formed on sidewalls of dielectric-filled trenches. In one embodiment, a semiconductor device is formed in a first semiconductor layer having trenches and mesas formed thereon where the trenches extend from the top surface to the bottom surface of the first semiconductor layer. The semiconductor device includes semiconductor regions formed on the bottom surface of the mesas of the first semiconductor layer.
US08729600B2 Insulated gate bipolar transistor (IGBT) with hole stopper layer
A semiconductor device has a first conductivity-type semiconductor substrate, second conductivity-type channel regions, and second conductivity-type thinning-out regions. The channel regions and the thinning-out regions are formed adjacent to a substrate surface of the semiconductor substrate. Further, a hole stopper layer is formed in each of the thinning-out regions to divide the thinning-out region into a first part adjacent to the substrate surface and a second part adjacent to a bottom of the thinning-out region. The hole stopper layer has an area density of equal to or less than 4.0×1012 cm−2 to permit a depletion layer to punch through the hole stopper layer, thereby to restrict breakdown properties from being decreased.
US08729599B2 Semiconductor device
A method for fabricating a semiconductor device includes the following steps. First, a semiconductor substrate is provided, and a first region, a second region and a third region are defined thereon. Then, a first well having a first conductive type is formed in the semiconductor substrate of the first region and the second region, respectively. A semiconductor layer partially overlapping the first well of the second region is formed. Furthermore, a second well having a second conductive type is formed in the semiconductor substrate of the third region and the first well of the second region respectively, where the second well of the second region is disposed underneath the semiconductor layer.
US08729598B2 Light-emitting diode, method for manufacturing the same, and light-emitting diode lamp
The present invention provides a light-emitting diode that includes two electrodes provided on a light-emitting surface, and exhibits high light extraction efficiency and high-brightness. The present invention relates to a light-emitting diode (1) including: a compound semiconductor layer (2) including a light-emitting portion (7) containing a light-emitting layer (10); and a transparent substrate (3), wherein the compound semiconductor layer (2) and the transparent substrate (3) are bonded, and a first electrode (4) and a second electrode (5) are provided on the side of a main light-emitting surface (2a) of the compound semiconductor layer (2), wherein the transparent substrate (3) includes: an upper surface (3A) bonding to the compound semiconductor layer (2); a bottom surface (3B) having smaller dimensions than dimensions of the upper surface (3A); and a side surface including at least inclined surface (3b) inclined from the side of the upper surface toward the side of the bottom surface, wherein the first and second electrodes (4) and (5) are disposed within a region in which the bottom surface (3B) is projected when viewed from the top of the light-emitting diode.
US08729597B2 Control method for device using doped carbon-nanostructure and device comprising doped carbon-nanostructure
Provided is a method for controlling a device using a doped carbon-nanostructure, and a device including the doped carbon-nanostructure, in which the method for controlling the device selectively controls the mobility of electrons or holes using N-type or P-type doped carbon-nanostructure; the N-type or P-type impurities-doped carbon-nanostructure can selectively control the transport of electrons or holes according to a doped material; and also since the doped carbon-nanostructure limits the transport of charge that is the opposite charge to the transport facilitating charge, it can improve the efficiency of device by adding to a functional layer of device or using as a separate layer in the electrons or holes-only transporting device.
US08729595B2 Light emitting device having vertical structure and package thereof
A light emitting device having a vertical structure and a package thereof, which are capable of damping impact generated in a substrate separation process, and achieving an improvement in mass productivity. The device and package include a sub-mount, a first-type electrode, a second-type electrode, a light emitting device, a zener diode, and a lens on the sub-mount.
US08729593B2 Substrate with wavy surface to control specular visibility for electronic device and electronic device using same
Provided is an electronic device having a long life and a large effective area. Furthermore, provided is an optical device capable of controlling specular visibility. And provided is a substrate for the optical device, which includes a scattering layer having excellent scattering properties and having a desired refractive index while retaining surface smoothness. Further, there is provided a substrate for the electronic device, which includes a substrate having first and second main surfaces facing each other and an electrode pattern formed on the first main surface of the substrate, in which the first main surface of the first and second main surfaces is a surface which forms waviness made up of curved faces, the waviness of the surface has a wavelength Rλa of greater than 50 μm and a ratio Ra/Rλa of waviness roughness Ra of the surface which forms waviness to the wavelength Rλa of the waviness is from 1.0×10−4 to 3.0×10−2.
US08729587B2 Nitride semiconductor element and manufacturing method therefor
An exemplary nitride-based semiconductor device includes: a nitride-based semiconductor multilayer structure 20 which has a p-type GaN-based semiconductor region whose surface 12 is inclined from the m-plane by an angle of not less than 1° and not more than 5° or the principal surface has a plurality of m-plane steps; and an electrode 30 that is arranged on the p-type GaN-based semiconductor region. The electrode 30 includes a Mg alloy layer 32 which is formed from Mg and metal selected from a group consisting of Pt, Mo, and Pd. The Mg alloy layer 32 is in contact with the surface 12 of the p-type GaN-based semiconductor region of the semiconductor multilayer structure 20.
US08729586B2 Light-emitting diode device
A light-emitting diode device includes: a substrate; an upper metal film disposed on an upper surface of the substrate, and including a chip-mounting region and a plurality of conductive pad regions; two first light-emitting chips and two second light-emitting chips disposed on the chip-mounting region, the first and second light-emitting chips being disposed alternately, two of the first and second light-emitting chips being opposite to each other; a fluorescent layer coated on the first light-emitting chips; and a lens disposed on the substrate to cover the first and second light-emitting chips and the fluorescent layer.
US08729584B2 Lighting system
The present invention relates to a light emitting device (1) comprising a light emitter (10) and a support (13) to which a plurality of protruding fibers (11) are attached. The light emitter (10) and the protruding fibers (11) are arranged to interact with light emitted from the light emitter (10) so that the light may be diffused. The plurality of protruding fibers comprises fibers (11) which are inclined or perpendicular in relation to the support (13).
US08729582B2 Optoelectronic device with light directing arrangement and method of forming the arrangement
An optoelectronic device (20) comprises a body (14) of an indirect bandgap semiconductor material having a surface (16) and a photon active region (12) on one side of the surface. A fight directing arrangement (22) is formed integrally with the body on an opposite side of the surface.
US08729580B2 Light emitter with metal-oxide coating
A light emitting device based on a AlInGaN materials system wherein a coating is used to improve the extraction of light from a device. A coating has a very low optical loss and an index of refraction greater than 2. In a preferred embodiment the coating is made from Ta2O5, Nb2O5, TiO2, or SiC and has a thickness between about 0.01 and 10 microns. A surface of a coating material may be textured or shaped to increase its surface area and improve light extraction. A surface of the coating material can also be shaped to engineer the directionality of light escaping the layer. A coating can be applied directly to a surface or multiple surfaces of a light emitting device or can be applied onto a contact material. A coating may also serve as a passivation or protection layer for a device.
US08729579B2 Nitride-based semiconductor light-emitting element, lighting device, liquid crystal display device, and method for producing lighting device
An illuminating device includes at least first and second nitride-based semiconductor light-emitting elements each having a semiconductor chip with an active layer region. The active layer region is at an angle of 1° or more with an m plane, and an angle formed by a normal line of a principal surface in the active layer region and a normal line of the m plane is 1° or more and 5° or less. The first and second nitride-based semiconductor light-emitting elements have thicknesses of d1 and d2, respectively, and emit the polarized light having wavelengths λ1 and λ2, respectively, where the inequalities of λ1<λ2 and d1
US08729578B2 Semiconductor light emitting device and method for manufacturing the same
According to one embodiment, a semiconductor light emitting device includes a first semiconductor layer, a second semiconductor layer and a light emitting layer. The second semiconductor layer is provided on a [0001]-direction side of the first semiconductor layer. The light emitting layer includes a first well layer, a second well layer and a first barrier layer. An In composition ratio of the barrier layer is lower than that of the first well layer and the second well layer. The barrier layer includes a first portion and a second portion. The second portion has a first region and a second region. The first region has a first In composition ratio higher than that of the first portion. The second region is provided between the first region and the first well layer. The second region has a second In composition ratio lower than the first In composition ratio.
US08729572B2 Light emitting diode package having a voltage stabilizing module consisting of two doping layers
A light emitting diode package includes an electrically insulated base, first and second electrodes, an LED chip, a voltage stabilizing module, and an encapsulative layer. The base has a first surface and an opposite second surface. The first and second electrodes are formed on the first surface of the base. The LED chip is electrically connected to the first and second electrodes. The voltage stabilizing module is formed on the first surface of the base, positioned between and electrically connected to the first and second electrodes. The voltage stabilizing module connects to the LED chip in reverse parallel and has a polarity arranged opposite to that of the LED chip. The voltage stabilizing module has an annular shape and encircles the first electrode. The encapsulative layer is formed on the base and covers the LED chip.
US08729570B2 Mask frame assembly for thin film deposition, organic light-emitting display device using the same, and method of manufacturing the organic light-emitting display device
A mask frame assembly for thin film deposition, an organic light-emitting display device using the same, and a method of manufacturing the organic light-emitting display device. The organic light-emitting display device includes a first electrode and a second electrode patterned on a substrate to face each other, and a plurality of organic layers formed between the first and second electrodes. The plurality of organic layers include at least a plurality of stripe-shaped organic layers and a plurality of discontinuous dot-shaped organic layers.
US08729569B2 Light-emitting chip, print head and image forming apparatus
The light-emitting chip includes: a substrate; plural light-emitting thyristors each having a pnpn structure formed of a first stacked-semiconductor layer in which at least 4 semiconductor layers having different conductivity types and including the substrate are stacked on the substrate; a lower wiring that is formed of a second stacked-semiconductor layer in which at least 3 semiconductor layers having different conductivity types and including the substrate are stacked on the substrate, and that has a semiconductor layer between the substrate and an uppermost semiconductor layer of the second stacked-semiconductor layer, the semiconductor layer having a fixed potential so that any one of p-n junctions between the substrate and the uppermost semiconductor layer is reversely biased with respect to potentials respectively applied to the substrate and the uppermost semiconductor layer; and an upper wiring provided on the lower wiring so as to intersect with the lower wiring through an isolation layer.
US08729567B2 Silicon carbide semiconductor device
A silicon carbide semiconductor device includes a silicon carbide substrate, and a contact electrode. The silicon carbide substrate includes an n type region and a p type region in contact with the n type region. The contact electrode forms contact with the silicon carbide substrate. The contact electrode includes a first region containing TiSi, and a second region containing Al. The first region includes an n contact region in contact with the n type region and a p contact region in contact with the p type region. The second region is formed to contact the p type region and the n type region, and to surround the p contact region and the n contact region. Accordingly, there can be provided a silicon carbide semiconductor device including an electrode allowing ohmic contact with both a p type impurity region and an n type impurity region formed at a silicon carbide substrate.
US08729563B2 Solid state lighting devices with selected thermal expansion and/or surface characteristics, and associated methods
Solid state lighting (SSL) devices and methods are disclosed. A particular method includes forming an SSL formation structure having a CTE, selecting a first material of an interlayer structure to have a first material CTE greater than the substrate CTE, and selecting a second material based at least in part on the second material having a CTE less than the first material CTE. The intelayer structure is formed over the SSL formation structure e.g., with a first layer of the first material over the SSL formation structure, a portion of the second material over the first material, and a second layer of the first material over the second material. The CTE difference between the first and second materials can counteract a force placed on the formation structure by the first material. Particular formation structures can have an off-cut angle with a non-zero value of up to about 4.5 degrees.
US08729557B2 Electroluminescence display device
Disclosed is an electroluminescence device having a substrate, a thin film transistor over the substrate, an insulating film over the thin film transistor, an electroluminescence element over the insulating film, a passivation film over the electroluminescence element, and a counter substrate over the passivation film. The electroluminescence element is configured to emit light through the counter substrate, and a space between the substrate and the counter substrate is filled with a filler. The electroluminescence device is featured by the tapered side surface of a gate electrode of the thin film transistor.
US08729550B2 Semiconductor device and method for manufacturing semiconductor device
An object is to reduce the manufacturing cost of a semiconductor device. An object is to improve the aperture ratio of a semiconductor device. An object is to make a display portion of a semiconductor device display a higher-definition image. An object is to provide a semiconductor device which can be operated at high speed. The semiconductor device includes a driver circuit portion and a display portion over one substrate. The driver circuit portion includes: a driver circuit TFT in which source and drain electrodes are formed using a metal and a channel layer is formed using an oxide semiconductor; and a driver circuit wiring formed using a metal. The display portion includes: a pixel TFT in which source and drain electrodes are formed using an oxide conductor and a semiconductor layer is formed using an oxide semiconductor; and a display wiring formed using an oxide conductor.
US08729548B2 Method of manufacturing a semiconductor device
The present invention supplies a manufacturing method of a semiconductor device, which includes a non-contact inspection process capable of confirming if a circuit or circuit element formed on an array substrate is normally performed and can decrease a manufacturing cost by eliminating wastes to keep a defective product forming.An electromotive force generated by electromagnetic induction is rectified and shaped by using primary coils formed on a check substrate and secondary coils formed on an array substrate, whereby a power source voltage and a driving signal are supplied to circuits or circuit elements on a TFT substrate so as to be driven.
US08729547B2 Method for manufacturing semiconductor device
To provide a method by which a semiconductor device including a thin film transistor with excellent electric characteristics and high reliability is manufactured with a small number of steps. After a channel protective layer is formed over an oxide semiconductor film containing In, Ga, and Zn, a film having n-type conductivity and a conductive film are formed, and a resist mask is formed over the conductive film. The conductive film, the film having n-type conductivity, and the oxide semiconductor film containing In, Ga, and Zn are etched using the channel protective layer and gate insulating films as etching stoppers with the resist mask, so that source and drain electrode layers, a buffer layer, and a semiconductor layer are formed.
US08729542B2 Organic electroluminescence element
Providing an organic electroluminescence element that can reduce the unevenness of the brightness and can improve the external quantum efficiency. The organic electroluminescence element includes a substrate 10, a first electrode 20, a second electrode 40, a functional layer 30 interleaved between the first electrode 20 the second electrode 40 and including a light emission layer 32, and a conductive layer 50. The resistivities of the first electrode 20 and the second electrode 40 are less than the resistivity of transparent conductive oxide. The second electrode 40 has an opening for light extraction. The functional layer 30 includes, as the outermost layer on the second electrode 40 side, a carrier injection layer 34. The conductive layer 50 is optically transparent and is in contact with the second electrode 40 and the functional layer 30. The carrier injection layer 34 has a recess in the projection domain of the opening.
US08729541B2 Phenanthrene compound and organic light emitting device using the same
The present invention provides an organic light emitting device having high light emission efficiency. The organic light emitting device includes an anode, a cathode and an organic compound layer which is sandwiched between the anode and the cathode, wherein the organic compound layer contains a phenanthrene compound represented by the following general formula [1]: wherein R1 to R3 each represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; and Ar is a substituent selected from any in the group consisting of aryl groups represented by the following formulae [2a] to [2h]:
US08729540B2 Electroluminescent organic transistor
The present invention relates to a field effect electroluminescent ambipolar organic transistor in which there are two couples of control electrodes, a layer of ambipolar organic semiconductor in direct contact with the source and the drain electrode and two separate dielectric layers, and wherein said dielectric layers are each arranged between the ambipolar organic semiconductor layer and a couple of control electrodes.
US08729539B2 Light-emitting apparatus
Provided is a light-emitting apparatus which, without using an insulating film for separating pixels, inhibits leakage current between adjacent pixels and which accommodates higher resolution. By providing a groove in an insulating layer along an edge of a first electrode, the thickness of a first charge transport layer is reduced to inhibit leakage current between adjacent pixels.
US08729530B2 Material for light-emitting device and light-emitting device
The present invention provides a light emitting device material which enables a light emitting device having high efficiency and excellent chromatic purity and durability using a light emitting device material containing a pyrene compound represented by formula (1), wherein any one of R1 to R10 is a group represented by formula (2), or 1 to 4 substituents is/are group(s) represented by formula (3), and a light emitting device using the same.
US08729526B2 Optical semiconductor device and method of manufacturing optical semiconductor device
An optical semiconductor device includes a substrate; and an active layer disposed on the substrate, wherein the active layer includes a first barrier layer containing GaAs, a quantum dot layer, which is disposed on the first barrier layer, which includes a quantum dot containing InAs, which includes a side barrier layer which covers at least a part of the quantum dot and a side surface of the quantum dot, and having an elongation strain inherent therein, and a second barrier layer disposed on the quantum dot layer.
US08729525B2 Opto-electronic device
The present application relates to an opto-electronic device. The opto-electronic device includes an n-cladding layer, a p-cladding layer and a multi-quantum well structure. The multi-quantum well structure is located between the p-cladding layer and the n-cladding layer, and includes a plurality of barrier layers, a plurality of well layers and a barrier tuning layer. The barrier tuning layer is made by doping the barrier layer adjacent to the p-cladding layer with an impurity therein for changing an energy barrier thereof to improve the light extraction efficiency of the opto-electronic device.
US08729520B2 Memory devices and formation methods
A method includes forming an electrical insulator material over an integrated circuit having a metal-containing conductive interconnect and activating a dopant in a semiconductor material of a substrate to provide a doped region. The doped region provides a junction of opposite conductivity types. After activating the dopant, the substrate is bonded to the insulator material and at least some of the substrate is removed where bonded to the insulator material. After the removing, a memory cell is formed having a word line, an access diode, a state-changeable memory element containing chalcogenide phase change material, and a bit line all electrically connected in series, the access diode containing the junction as a p-n junction. A memory device includes an adhesion material over the insulator material and bonding the word line to the insulator material.
US08729517B2 Nonvolatile semiconductor memory device and method for manufacturing nonvolatile semiconductor memory device
According to one embodiment, a nonvolatile semiconductor memory device includes a first interconnect, a second interconnect and a resistance change layer. The first interconnect extends in a first direction on a major surface of a substrate. The second interconnect extends in a second direction non-parallel to the first direction. The resistance change layer includes a conductive nanomaterial, the resistance change layer located between the first interconnect and the second interconnect and being capable of reversibly changing between a first resistance state and a second resistance state by a voltage applied or a current supplied through the first interconnect and the second interconnect. The resistance change layer has a density varied along a third direction generally perpendicular to the first direction and the second direction.
US08729516B2 Method and device for detecting metals in a fluid
A method detects metallic atoms in a fluid. The method includes: placing, in a zone sheltered from light, a photodiode comprising a photosensitive surface in contact with a fluid to analyze; heating the photosensitive surface of the photodiode to a temperature sufficient to allow metallic atoms deposited on the photosensitive surface to migrate through this surface; acquiring a signal relative to the lighting of the photodiode; and determining, from the acquired signal, a measurement representative of a contamination status by metallic atoms of the photodiode.
US08729515B2 Pinned contact, oscillating liquid-liquid lens and imaging systems
An oscillating liquid lens and imaging system and method employing the lens are provided. The liquid lens includes a substrate with a channel opening extending through the substrate. A liquid drop is disposed within the channel and is sized with a first droplet portion, including a first capillary surface, protruding away from a first substrate surface, and a second droplet portion, including a second capillary surface, protruding away from a second substrate surface. The liquid lens further includes an enclosure at least partially surrounding the substrate, and including a chamber. The liquid drop resides within the chamber, and the liquid lens includes a second liquid disposed within the chamber in direct or indirect contact with the liquid drop, and the liquid lens further includes a driver for oscillating the liquid drop within the channel.
US08729508B2 Beam transport system for a hadron therapy facility
A beam transport system for a hadron therapy facility comprises: a main beam transport line; secondary beam transport lines branching off from the main beam transport line for delivering the hadron beam into the patient treatment stations; and switching electromagnets for deviating the hadron beam from the main beam transport line into the secondary beam transport line. A discharge circuit associated with each switching electromagnet comprises a discharge accelerating circuit capable of generating a voltage opposing the counter electromotive force induced in the electromagnet coil of the switching electromagnet when the energization of the electromagnet coil producing the hadron beam deviation is interrupted, wherein this voltage stays substantially constant or increases as the current induced in the electromagnet coil decreases.
US08729502B1 Simultaneous, single-detector fluorescence detection of multiple analytes with frequency-specific lock-in detection
Microfluidics has made great progress in integrating many aspects of biological analysis and testing into the microscale. One aspect which has proven challenging to miniaturize has been fluorescence testing, as a complete fluorescence system requires an integrated light source, detector and filters to filter out the excitation light (from the light source) from the detector. Here we demonstrate that with polarization filtering of the excitation light and multiple dye sources modulated at different frequencies, a high-sensitivity, multi-dye system with one detector can be realized. Simultaneous detection and quantition of a mixture of two different dyes is demonstrated with no physical change in the measurement setup. The degree of interaction of the dyes is measured. This system is readily adaptable to integrated lab-on-a-chip microfluorescence.
US08729501B2 Ultraviolet irradiation device for implants
Disclosed herein is an ultraviolet irradiation device for removing organic contaminants from implants using ultraviolet rays. In the present invention, the implants can be easily and smoothly put into or pulled out of a processing chamber, and the implants can be reliably prevented from being recontaminated after the ultraviolet irradiation process has finished. For this, the ultraviolet irradiation device includes a housing provided with an openable door, an ultraviolet lamp installed in the housing, a carriage provided in the housing so as to be extractable, and an implant mount unit placed on the carriage in such a way that the implant mount unit can be disposed facing the ultraviolet lamp in the housing. The implant mount unit includes a mounting board removably placed on the carriage, and an implant support removably placed on the mounting board.
US08729498B2 High throughput UV curing systems and methods of curing a plurality of articles
High throughput UV curing systems for mass curing of a plurality of articles without compromising product quality. The systems comprise a plurality of UV banks, each bank comprising a plurality of fluorescent UV lamps, thereby creating a consistent blanket of UV energy. A plurality of coated articles are positioned between pairs of banks such that the UV exposure or dosage is evenly distributed for each article. The fluorescent UV lamps use proportionally lower energy per unit and generate less heat than standard UV lamps, while sufficiently curing the coating on each article. Throughput is increased compared to currently available systems because the systems are easier to maintain requiring less downtime, can cure significantly more articles per cycle, and reduce the number of rejected products.
US08729491B2 Charged particle beam apparatus
The present invention provides a charged particle beam apparatus which is provided with a tilting deflector which is disposed between a charged particle source and an objective lens and tilts a charged particle beam, wherein a first optical element includes an electromagnetic quadrupole which generates dispersion to suppress the dispersion which is generated by deflection by the tilting deflector, and a second optical element is composed of a deflector for deflecting the charged particle beam which enters the first optical element or an electromagnetic quadrupole which causes the charged particle beam to generate a dispersion different from the dispersion generated by the first optical element.
US08729490B2 Method of energy spectrum analysis for sodium iodide (NaI) detector
The present invention relates to a method of energy spectrum analysis for sodium iodide (NaI) detector, by which an energy spectrum characteristic obtained from a sodium iodide (NaI) detector is analyzed and used for establishing a system capable of qualitative nuclide identification and activity determination that can be adapted in applications of waste clearance management.
US08729488B2 Assaying of waste
A method for investigating a volume of material at an investigation location for radioactive material includes: detecting signals from a first detector caused by the interaction of one or more types of emission from the radioactive material with the first detector; detecting signals from a second detector caused by the interaction of cosmic rays and/or one or more types of particle generated by cosmic rays with the second detector; processing the signals from the first detector to provide information on the amount of radioactive material associated with the volume of material; processing the signals from the second detector to provide information on the amount of cosmic rays and/or one or more types of particle generated by cosmic rays incident on the investigation location; and correcting the information on the amount of radioactive material associated with the volume of material using the amount of cosmic rays and/or one or more types of particle generated by cosmic rays incident on the investigation location, thereby providing corrected information on the amount of radioactive material associated with the volume of material.
US08729487B2 Neutron detector and method of making
A neutron detector comprises at least two conductive cathode sheets lying parallel to one another and coated with neutron reactive material on at least one side thereof; dielectric material separating the cathode sheets and covering less than about 80% of their surface area; and a plurality of anode wires lying generally parallel to the cathode sheets and separated from them by the dielectric, with the distance between adjacent anode wires being no more than twenty times the distance between said cathode sheets. The cathode sheets may be flat or curved; they may be separate plates or they may be successive folds or windings of a single folded or spiral-shaped metal sheet. Related methods for building the detector are disclosed.
US08729485B2 Parallel mode readout integrated circuit for X-ray image sensor
Embodiments of the present invention provide a computer-implemented method for parallel readout for an X-ray image sensor module having a pixel array. Specifically, among other things, embodiments of the present invention provide a computer-implemented infrastructure comprising: generating a pixel data for each pixel within a respective pixel row of the pixel array based on a photon count; receiving a first serial pixel data, wherein the first serial pixel data comprises pixel data from a plurality of pixels of a first column; receiving a second serial pixel data, wherein the second serial pixel data comprises pixel data from a plurality of pixels of a second column; and shifting the first serial pixel data from the first column register to the second column register.
US08729484B2 Radiographic imaging device and radiographic imaging system
There is provided a radiographic imaging device including: an imaging panel at which sensor portions, that detect radiation or light converted from radiation, are formed at a detection region, and that captures a radiographic image expressed by radiation or light converted from radiation; a light illuminating section at which light-emitting portions, that can individually illuminate light for erasing residual images, are provided per sectional region obtained by dividing the detection region into the sectional regions; a storage section that stores imaging actual results information that expresses past actual results of imaging carried out by the imaging panel; and a control section that, in accordance with at least one of actual results of imaging and imaging conditions, controls absence/presence of illumination of, light amount of, and illumination time period of light from the respective light-emitting portions of the light illuminating section.
US08729480B2 Tomography scanner with axially discontinuous array
A tomography scanner has intentionally designed, well defined gaps between detector rings with image reconstruction obtained with the use of conventional tomography data processing. The scanner is particularly advantageous as a small animal PET scanner.
US08729473B2 Infrared light transmissivity for a membrane sensor
In conventional membrane infrared (IR) sensors, little to no attention has been paid toward transmissivity of IR near metal traces. Here, because the substrate of an integrated circuit carrying the sensor is used as a visible light filter, reflection of IR radiation back into the substrate can affect the operation and reliability of the IR sensor. As a result, an arrangement is provided that reduces the area occupied by metal lines by reducing the pitch and compacting the routing so as to reduce the effects from the reflection of IR radiation by metal traces.
US08729469B1 Multiple sample attachment to nano manipulator for high throughput sample preparation
An improved method for extracting and handling multiple samples for S/TEM analysis is disclosed. Preferred embodiments of the present invention make use of a micromanipulator that attaches multiple samples at one time in a stacked formation and a method of placing each of the samples onto a TEM grid. By using a method that allows for the processing of multiple samples, the throughput of sample prep in increased significantly.
US08729468B2 Microelectronic substrate inspection equipment using helium ion microscopy
Microelectronic substrate inspection equipment includes a gas container which contains helium gas, a helium ion generator which is disposed in the gas container and converts the helium gas into helium ions and a wafer stage which is disposed under the gas container and on which a substrate to be inspected is placed. The equipment further includes a secondary electron detector which is disposed above the wafer stage and detects electrons generated from the substrate, a compressor which receives first gaseous nitrogen from a continuous nitrogen supply device and compresses the received first gaseous nitrogen into liquid nitrogen, a liquid nitrogen dewar which is connected to the compressor and stores the liquid nitrogen, and a cooling device that is coupled to the helium ion generator. The cooling device is disposed on the gas container, and cools the helium ion generator by vaporizing the liquid nitrogen. Related methods are also disclosed.
US08729458B2 Encoder
A detection head includes a plurality of detection array portions that are arranged in a direction along which the head is relatively displaceable. Position signals indicating a position of the detection head are calculated from output signals output from the detection array portions. In order to combine the position signals with one another and determine the position of the detection head with respect to the scale, weighting according to a level of the output signal is performed on the position signal of each of the detection array portions, and the weighted position signals are averaged.
US08729456B2 Frequency selective electromagnetic detector
An apparatus, system, and method are disclosed for a frequency selective electromagnetic detector. In particular, the frequency selective electromagnetic detector includes a nanowire array constructed from a plurality of nanowires of different compositions. At least one nanoparticle-sized diameter thermoelectric junction is formed between the nanowires of different compositions. When a nanoparticle-sized diameter thermoelectric junction senses a photon, the nanoparticle-sized diameter thermoelectric junction emits an electrical pulse voltage that is proportional to an energy level of the sensed photon. In one or more embodiments, the frequency selective electromagnetic detector is a frequency selective optical detector that is used to sense photons having optical frequencies. In at least one embodiment, at least one of the nanowires in the nanowire array is manufactured from a compound material including Bismuth (Bi) and Tellurium (Te).
US08729450B2 Solid-state imaging device, method of manufacturing solid-state imaging device, and imaging apparatus
There is provided a solid-state imaging device including a semiconductor substrate having an effective region in which a photodiode performing a photoelectric conversion is formed and, an optical black region shielded by a light shielding film; a first film which is formed on the effective region and in which at least one layer or more of layers having a negative fixed charge are laminated; and a second film which is formed on the light shielding region and in which at least one layer or more of layers having a negative fixed charge are laminated, in which the number of layers formed in the first film is different from the number of layers formed in the second film.
US08729447B2 Microchannel plate and its manufacturing method
A microchannel plate (1) having an array of channels (5),includes a substrate (2) and, deposited on the substrate, a hydrogenated amorphous silicon film (3) having a thickness ranging between 50 μm and 200 μm, preferably between 80 μm and 120 μm, the film including the array of channels (5). Preferably, the substrate (2) is an integrated circuit having an internal electronic readout circuit and pixilated collection electrodes (8), and the film (3) is integrated on the substrate (2). The channels (5) may be formed by a Deep Reactive Ion Etching (DRIE) process.
US08729445B2 Load-matched photo-voltaic power unit
Load-matched photo-voltaic power units incorporating a plurality of photo-voltaic cells for delivery of electrical power are described. A photo-voltaic system incorporates temperature and solar irradiance sensors, whose outputs are used to estimate the photo-voltaic system maximum power output voltage. Appropriate numbers of cells are suitably interconnected to assemble at least one photo-voltaic power unit intended to both satisfy the electrical requirements of a load and enable operation of the unit at an efficiency of 90% or greater of its maximum efficiency. In an embodiment, voltage-to-voltage convertors may be used to better match the photo-voltaic power unit capabilities to the load requirements. In another embodiment an alert is issued if the photo-voltaic power unit delivers a voltage which differs by a predetermined amount from an estimated maximum power voltage.
US08729443B2 Projectile and method that include speed adjusting guidance and propulsion systems
Some embodiments pertain to a projectile and method that includes a flight vehicle and a propulsion system attached to the flight vehicle. The propulsion system includes a plurality of motors that propel the projectile. A guidance system is connected to the propulsion system. The guidance system ignites an appropriate number of the motors to adjust the speed of the projectile based on the location of the projectile relative to a desired destination for the flight vehicle. In some embodiments, the flight vehicle is a kinetic warhead. The projectile may be an interceptor that includes a first propulsion stage, a second propulsion stage and a third propulsion stage that includes the third propulsion system. The number of booster motors that will be ignited by the guidance system depends on the speed that the projectile needs to be adjusted to in order to maneuver the projectile to a desired location.
US08729441B2 High-frequency heating apparatus
There is provided a high-frequency heating apparatus including a heating chamber that houses an object to be heated, a rotating turntable provided on a bottom surface of the heating chamber, on which the object to be heated is rotatably mounted; a high-frequency heating section (21) that heats the object to be heated which is housed in the heating chamber, a convection heater (27) for heating the heating chamber, a circulating fan (28) for supplying the heating chamber with heat of the convection heater (27) as hot air, and a grill heater (33) for heating the object to be heated, wherein the convection heater (27) and the grill heater (33) are separately disposed on an upper surface of the heating chamber, thereby allowing reduction in size of an external shape of the heating apparatus without sacrificing grill cooking performance and oven cooking performance.
US08729440B2 Applicator and method for RF heating of material
A radio frequency heater is disclosed including a vessel for containing material to be heated and a radio frequency radiating surface. The vessel has a wall defining a reservoir. The radio frequency radiating surface at least partially surrounds the reservoir. The radiating surface includes two or more circumferentially spaced petals that are electrically isolated from other petals. The petals are positioned to irradiate at least a portion of the reservoir, and are adapted for connection to a source of radio frequency alternating current. A generally conical tank or tank segment having a conically wound radio frequency applicator is also contemplated. Also, a method of heating an oil-water process stream is disclosed. In this method a radio frequency heater and an oil-water process stream are provided. The process stream is irradiated with the heater, thus heating the water phase of the process stream.
US08729436B2 Drying process and apparatus for ceramic greenware
A method and system for drying a honeycomb structure having an original liquid vehicle content includes exposing the honeycomb structure to a first electromagnetic radiation source until the liquid vehicle content is between about 20% and about 60% of the original liquid vehicle content, exposing the honeycomb structure to a second electromagnetic radiation source different from the first electromagnetic radiation source until the liquid vehicle content is between about 0% and about 30% of the original liquid vehicle content, and exposing the honeycomb structure to convection heating until the liquid vehicle content is between about 0% and about 30% of the original liquid vehicle content.
US08729434B2 Induction cooking device
An induction cooking device includes a heating coil performing induction heating of a cooking container placed on a top plate, an inverter circuit supplying high frequency current to the heating coil, an infrared sensor detecting an amount of infrared light radiated from the cooking container and outputting a detection signal based on the detected amount, a temperature sensor detecting a temperature of the cooking container by thermal conduction through the top plate, and a control unit controlling an output of the inverter circuit so that the outputs of the infrared and temperature sensors do not exceed the respective control temperature. The control unit judges whether or not the infrared sensor is normally detecting the temperature of the cooking container, and when it is judged that the infrared sensor is normally detecting the temperature of the cooking container, the control unit raises the control temperature of the temperature sensor.
US08729433B2 Electrical heating device and method for the production thereof
An electrical heating device includes an open housing in which a layer structure is held under tension. The layer structure includes at least one radiator element and at least one heat emitting element with at least one PTC heating element. The layer structure further includes at least one spring element holding the layer structure in the housing under tension. The spring element is provided adjacent to a spring counter element. Spring tongues, formed on the spring element, interact with matching receptacles on the spring counter element. Displacement of the spring element in a direction essentially parallel to the planes of the layer structure stresses the layer structure within the housing. A method of assembling an electrical heating device is also disclosed.
US08729432B2 Capacitance sensing switch module
A capacitance sensing switch module is provided. The capacitance sensing switch module for controlling a cooktop includes a plate, at least one key, an insulating pad, a circuit board and at least one foil. The plate is disposed in a side of the cooktop and has at least one hole passing through the plate. The key is disposed in the hole. The insulating pad is disposed between the key and the plate. The key and the plate are separated by the insulating pad. The circuit board is disposed under the plate. The foil is disposed on the circuit board and on the position corresponding to the key. There is an insulation gap between the foil and the key.
US08729430B2 Seat heater and capacitive occupancy sensor combination
A combined seat heater and capacitive occupancy sensor comprises a heater network and a capacitive sensing network. The heater network includes a heating element (10) connected between a first node (21) and a second node (22) to dissipate heat. The capacitive sensing network is connected to the heating element to apply an oscillating current thereto and to derive a capacitive load of the heating element from the voltage resulting on the heating element. The heater network comprises a common mode choke (16) connecting the first and the second node to a third (23) and a fourth (24) node, respectively. The capacitive sensing network further comprises means to sustain the oscillating current in or to drive the oscillating current into the heating element as well as a high-impedance amplifier (32) having an input node operatively connected to the heating element to probe the resulting voltage, and an output node (44) to provide an output signal indicative of the voltage.
US08729429B2 Method of storing and displaying heated food
A heated food storage and display cabinet including a flow inducer and heater arranged in an upper region thereof, the flow inducer being operable to draw air from an upper portion of the cabinet, to direct the air over the heater, and subsequently urge the heated air down the rear wall of the cabinet and across the floor of the cabinet towards the open front of the cabinet. The heated air is subsequently directed upwardly and rearwardly across the open front of the cabinet by an airflow direction member of the cabinet so as to provide a heated air curtain across the open front of the cabinet, and a portion of the heated air is also passed into the cabinet as the heated air moves down the rear wall and across the floor so as to pass over and around packs of food stored therein.
US08729428B1 Welding rod expander assembly
One embodiment of a welding rod expander assembly is useful for expanding a welding rod to a remote location. The welding rod expander assembly may include a first attachment member, a second attachment member, at least one elongated member and a welding rod holder. The second attachment member may be pivotally carried by the first attachment member. Further the at least one elongated member may have an external threaded end portion and a connecting end portion. The welding rod holder may be carried by the second attachment member. The welding rod holder may include a holding unit carried by the second internal threaded portion. The holding unit may be capable of receiving the welding rod. The welding rod holder may further include a clamping unit disposed on the second internal threaded portion. Further, the welding rod secured in the holding unit may be capable of expanding to the remote location.
US08729424B2 Hybrid welding with multiple heat sources
A method of welding a joint includes directing a first output from a high energy density heat source, such as a laser, against a first side of the joint. The method further includes directing a second output from an arc welding heat source, such as a gas metal arc welding torch, against a second side of the joint. The first output produces a keyhole surrounded by a molten metal pool which extends from the first side of the joint toward the second side of the joint. In some embodiments a third output from a second arc welding heat source may also be directed at the first side of the joint. A second molten metal pool produced by the arc welding heat source joins with the first molten metal pool and the third molten metal pool to form a common molten metal pool which solidifies to form the weld.
US08729423B2 System and method for supplying fluids to a plasma arc torch
A system for supplying fluids to a plasma arc torch includes a single-gas power supply for regulating electrical power to the torch and for regulating supply of a first fluid to the torch, a flow regulator for regulating supply of a second fluid to the torch, and a first pressure-actuated valve disposed between the flow regulator and the torch. The valve shuts off supply of the second fluid to the torch when the first valve is closed and allows the second fluid to be supplied when the first valve is open. The first valve is opened by pressure of the first fluid supplied to the torch and closed when the first fluid is not supplied to the torch. A second pressure-actuated valve may be provided in the supply line for the first fluid, which is opened by pressure of the second fluid being supplied to the torch.
US08729420B2 Machining condition adjusting device for electric discharge machine
Machining state information is acquired for each predetermined period by performing test machining by an electric discharge machine, and the acquired machining state information is compared with reference machining state information, whereby whether a machining state is satisfactory or not is determined. If the machining state is determined to be unsatisfactory, set items of a machining condition are adjusted. Thereafter, test machining is actually performed again, and the machining condition is adjusted by changing the set items if the machining state is determined again to be unsatisfactory. Thus, the acquisition of the machining state information, determination of the machining state, and adjustment of the machining condition are repeated so that satisfactory machining is finally determined.
US08729416B2 Circuit breaker remote tripping
A circuit breaker module (which may also be termed an interrupter) including circuit breaker contacts which are opened and closed by an electrically-activated magnetic actuator and capable of interrupting fault currents. The magnetic actuator is stable in either a breaker-closed state or a breaker-open state without requiring electrical current flow through the magnetic actuator. An externally-connectable mechanical drive is linked to the magnetic actuator in a manner such that movement of the externally-connectable mechanical drive can destabilize the breaker-closed state to open the circuit breaker contacts. An external actuator activated by an external condition is connected to said externally-connectable mechanical drive so as to cause said circuit breaker contacts to open upon occurrence of the external condition.
US08729414B2 Button assembly with inverted dome switch
A portable electronic device may have an inverted dome switch assembly. The switch assembly may have an inverted dome that has a base and a conductive underside. The base may be attached to a button member. Two electrical contacts in the button member may face the conductive underside. Corresponding conductive traces may be connected to the contacts. The dome may bear against a housing member. The button member may be movable with respect to the housing member from an unactuated position to an actuated position. The dome switch may form a footprint based upon the dome base area. The housing member may extend into a portion of the footprint and not into the remaining portion of the footprint allowing that space to be otherwise utilized.
US08729402B2 Polyimide precursor composition, use of the of the same, and production method of the same
An object of the present invention is to provide (i) a polyimide precursor composition which is curable at a low temperature (not more than 250° C.) and which has a low viscosity despite having a high concentration, and a production method thereof, (ii) a polyimide coating film obtained from the polyimide precursor composition and having good properties, and a production method thereof, (iii) a photosensitive resin composition prepared by use of the polyimide precursor composition, and a production method thereof. The object of the present invention can be attained by a polyimide precursor composition containing an imidized tetracarboxylic acid having a specific structure and an isocyanate compound having a specific structure, or optionally a diamine.
US08729400B2 Multilayer printed wiring board
An IC chip for a high frequency region, particularly a packaged substrate in which no malfunction or error occurs even if 3 GHz is exceeded. A conductive layer on a core substrate is formed at a thickness of 30 μm and a conductor circuit on an interlayer resin insulation layer is formed at a thickness of 15 μm. By thickening the conductive layer, the volume of the conductor can be increased and resistance can be reduced. Further, by using the conductive layer as a power source layer, the capacity of supply of power to an IC chip can be improved.
US08729393B2 Uncrosslinked polyethylene composition for power cable
The present invention is an uncrosslinked linear medium-density polyethylene resin composition for a power cable, which is applicable to an insulating layer, a semi-conducting layer or a sheath layer. Specifically, the uncrosslinked polyethylene composition includes: 100 parts by weight of a polymer having a linear medium-density polyethylene resin having an α-olefin having 4 or more carbon atoms as a comonomer and having a melt index of 0.6-2.2 g/10 min (at 190° C. under a load of 5 kg), a differential scanning calorimetry (DSC) enthalpy of 130-190 joule/g and a molecular weight distribution of 2-30; and 0.1 to 10 parts by weight of one or more additive(s) selected from a flame retardant, an oxidation stabilizer, a UV stabilizer, a heat stabilizer and a process aid.
US08729386B2 Semiconductor device and manufacturing method thereof
A semiconductor device is provided, which comprises a first electrode, crystalline semiconductor particles, a semiconductor layer, and a second electrode. The crystalline semiconductor particles of which adjacent particles are fusion-bonded, the crystalline semiconductor particles have a first conductivity type, and the semiconductor layer has a second conductivity type which is different from the first conductivity type.
US08729385B2 Collector grid and interconnect structures for photovoltaic arrays and modules
A interconnected arrangement of photovoltaic cells is readily and efficiently achieved by using a unique interconnecting strap. The strap comprises electrically conductive fingers which contact the top light incident surface of a first cell and extend to an interconnect region of the strap. The interconnect region may include through holes which allow electrical communication between top and bottom surfaces of the interconnect region. In one embodiment, the electrically conductive surface of the fingers is in electrical communication with an electrically conductive surface formed on the opposite side of the strap through the through holes of the interconnect region. The interconnection strap may comprise a laminating film to facilitate manufacture and assembly of the interconnected arrangement.
US08729382B2 Photovoltaic-charged secondary battery system
A photovoltaic-charged secondary battery system is provided, in which an electrode for optical power generation and an electrode for charging and discharging generated electrical energy are integrated into a single cell structure, and the potential difference between the electrodes is systematically controlled, thus maximizing the conversion efficiency of optical energy, maximizing the utilization rate of cell energy, and extending the life span of the battery. Thus, the photovoltaic-charged secondary battery system may include a transparent electrode capable of transmitting light; a PN semiconductor layer formed on the transparent electrode and generating a current by incident light; and a secondary battery layer, formed on the PN semiconductor layer, in which the current generated by the PN semiconductor layer is charged.
US08729380B2 Use of porous metallic materials as contact connection in thermoelectric modules
In the thermoelectric module composed of p- and n-conductive thermoelectric material legs which are connected to one another alternately via electrically conductive contacts, at least some of the electrically conductive contacts on the cold and/or the warm side of the thermoelectric module are formed between, or embedded into, the thermoelectric material legs composed of porous metallic materials.
US08729372B2 Adjuster for string instruments
An adjuster with a frame attachable to the front end portion of an instrument tailpiece, a lever member with a base portion and a front plate portion swingably supported by the frame, a mounting portion with an adjusting screw positioned therein, an anchoring portion extending from the lever member that projects through an anchor hole to the surface side of the tailpiece to removably anchor a string of the instrument, and a swing transmitting member provided to the frame so as to be interposed between the adjusting screw and the lever member. The swing transmitting member is swingably supported by the frame and includes one or more transmitting levers extending along the string. When the adjusting screw is screwed into the mounting portion, one end of the transmitting lever is pushed down and another end pushes up the lever member, and the anchoring portion is swung to stretch the string.
US08729368B1 Maize variety hybrid X08A153
A novel maize variety designated X08A153 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X08A153 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X08A153 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X08A153, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X08A153. This invention further relates to methods for producing maize varieties derived from maize variety X08A153.
US08729363B2 Plants and seeds of corn variety CV672639
According to the invention, there is provided seed and plants of the corn variety designated CV672639. The invention thus relates to the plants, seeds and tissue cultures of the variety CV672639, and to methods for producing a corn plant produced by crossing a corn plant of variety CV672639 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV672639 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV672639.
US08729362B2 Plants and seeds of corn variety CV431223
According to the invention, there is provided seed and plants of the corn variety designated CV431223. The invention thus relates to the plants, seeds and tissue cultures of the variety CV431223, and to methods for producing a corn plant produced by crossing a corn plant of variety CV431223 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV431223 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV431223.
US08729359B2 Plants and seeds of hybrid corn variety CH661125
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH661125. The invention thus relates to the plants, seeds and tissue cultures of the variety CH661125, and to methods for producing a corn plant produced by crossing a corn plant of variety CH661125 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH661125.
US08729358B2 Plants and seeds of hybrid corn variety CH098773
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH098773. The invention thus relates to the plants, seeds and tissue cultures of the variety CH098773, and to methods for producing a corn plant produced by crossing a corn plant of variety CH098773 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH098773.
US08729356B2 Plants and seeds of hybrid corn variety CH213992
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH213992. The invention thus relates to the plants, seeds and tissue cultures of the variety CH213992, and to methods for producing a corn plant produced by crossing a corn plant of variety CH213992 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH213992.
US08729355B2 Soybean cultivar S110128
A soybean cultivar designated S110128 is disclosed. The invention relates to the seeds of soybean cultivar S110128, to the plants of soybean cultivar S110128, to the plant parts of soybean cultivar S110128, and to methods for producing progeny of soybean cultivar S110128. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S110128. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S110128, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S110128 with another soybean cultivar.
US08729348B1 Soybean variety XBP37008
A novel soybean variety, designated XBP37008 is provided. Also provided are the seeds of soybean variety XBP37008, cells from soybean variety XBP37008, plants of soybean XBP37008, and plant parts of soybean variety XBP37008. Methods provided include producing a soybean plant by crossing soybean variety XBP37008 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XBP37008, methods for producing other soybean varieties or plant parts derived from soybean variety XBP37008, and methods of characterizing soybean variety XBP37008. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP37008 are further provided.
US08729343B2 Type of lettuce and methods of production
The present invention relates to an iceberg lettuce having one or more romaine lettuce characteristics. The invention further relates to methods for producing iceberg lettuce varieties containing one or more romaine lettuce characteristics.
US08729337B2 Production of polyunsaturated fatty acids, novel biosynthesis genes, and novel plant expression constructs
The present invention relates to a method for the production of unsaturated fatty acids with at least two double bonds. The invention furthermore relates to the use of nucleic acid sequences SEQ ID NO: 1, 3, 5, 9, and 11 encoding polypeptides having desaturase or elongase activity in the method and for generating a transgenic organism, preferably a transgenic plant or a transgenic microorganism, with an increased content of fatty acids, oils or lipids with unsaturated C18-, C20-, or C22-fatty acids, and to their homologs or derivatives, to gene constructs encompassing these genes, and to their use alone or in combination with biosynthesis genes of polyunsaturated fatty acids. The invention also relates to multiexpression cassettes for seed-specific expression, and to vectors or organisms which encompass a desaturase gene alone or in combination with further desaturases and/or elongase genes or homologs using said expression cassettes.
US08729336B2 Protein mixtures for maize insect control
Embodiments of the present invention relate to insecticidal Bacillus thuringiensis Cry1 and Cry2 polypeptides. Methods for using the polypeptides and nucleic acids of embodiments of the invention to synergistically enhance resistance of plants to insect predation are encompassed in embodiments of the present invention.
US08729333B2 Absorptive article
An absorptive article 1 includes a liquid-permeable top sheet 20, a liquid impermeable back sheet 30, and an absorber 50 disposed between the top sheet 20 and the back sheet 30. The absorber 50 has a layered structure including an upper absorbent layer 511 disposed on the side of the top sheet 20 and a lower absorbent layer 512 disposed on the side of the back sheet 30. The upper absorbent layer 511 is composed of virgin pulp and virgin polymer, and the lower absorbent layer 512 contains recycled pulp and recycled polymers.
US08729330B2 Hydroprocessing of diesel range biomolecules
Non-hydrotreated biocomponent feeds can be mixed with mineral feeds and processed under catalytic isomerization/dewaxing conditions. The catalytic isomerization/dewaxing conditions can be selected to advantageously also substantially deoxygenate the mixed feed. Diesel fuel products with improved cold flow properties can be produced.
US08729327B2 Process for cooling the stream leaving an ethylbenzene dehydrogenation reactor
The present invention is a process for the production of styrene monomer from ethylbenzene comprising the steps of: a) catalytically dehydrogenating said ethylbenzene in the presence of steam thereby catalytically producing a dehydrogenation effluent gas containing essentially unreacted ethylbenzene, styrene monomer, hydrogen, steam and divinylbenzene; b) quenching said effluent gas with an aqueous reflux in at least a quenching column to cool said effluent gas, and thereby obtaining a gas at the overhead and in the bottom a liquid stream warmer than the aqueous reflux; c) condensing said overhead gas thereby producing a liquid organic phase, an aqueous phase and a gaseous phase; d) using a portion or the whole of said aqueous phase of step c) as reflux for said step b) of quenching; e) sending to a decanter the liquid stream obtained at step b) to recover an aqueous phase and an organic phase.
US08729322B2 Hydrotreating carbohydrates
Conversion of renewable hydrocarbons to transportation fuels is required to reduce carbon emission, limit the use of fossil fuels, and develop renewable energy sources. Sorbitol, xylitol and trehelose are polyalcohols generated from the liquefaction of various sugars and carbohydrates in biomass from algae, corn, sugarcane, switchgrasses, and biological wastes. Mixtures of aqueous polyols and fuel feedstocks are catalyzed over metal catalysts to produce hexanes, pentanes, and lighter hydrocarbons. By managing the catalyst, reaction conditions and sulfur content, the octane value of the product fuel is dramatically increased.
US08729321B2 Fluoroalkyl iodide and its production process
A process for producing a fluoroalkyl iodide as a telomer Rf(CF2CF2)nI (wherein Rf is a C1-10 fluoroalkyl group, and n is an integer of from 1 to 6) by telomerization from a fluoroalkyl iodide represented by the formula RfI (wherein Rf is as defined above) as a telogen and tetrafluoroethylene (CF2CF2) as a taxogen, which comprises a liquid phase telomerization step of supplying a homogeneous liquid mixture of the telogen and the taxogen from the lower portion of a tubular reactor, moving the mixture from the lower portion towards the upper portion of the reactor in the presence of a radical initiator over a retention time of at least 5 minutes while the reaction system is kept in a liquid phase state is under conditions where no gas-liquid separation will take place, so that the taxogen supplied to the reactor is substantially consumed by the reaction in the reactor, and drawing the reaction product from the upper portion of the reactor.
US08729314B2 Process for the preparation of bronopol
The invention provides a process for preparing bronopol, which process comprises charging a reaction vessel with water, bromopicrin, nitromethane and paraformaldehyde, gradually feeding a base into said reaction vessel under stirring, bringing the reaction to completion and separating bronopol from the aqueous reaction mixture.
US08729312B2 Derivatives of novel peroxides, method of preparation thereof and use thereof in human medicine as well as in cosmetics for the treatment or prevention of acne
Compounds of the following general formula (I): are described. Also described, are methods of preparing the compounds and their use in therapeutics.
US08729300B2 Method for preparing metal salt of valproic acid
The present invention provides a simple, safe and more efficient process for preparing metal salts of valproic acid. The process includes steps of: (i) mixing valproic acid and a metal hydroxide (either dry solid or aqueous solution) in a drier to form a reaction mixture; and (ii) removing water, which is produced during the step of mixing the valproic acid and the metal hydroxide, from the reaction mixture to obtain the desired metal salts of valproic acid.
US08729299B2 Processes for the production of acrylic acids and acrylates
In one embodiment, the invention is to a process for producing an acrylate product. The process comprises the step of reacting a reaction mixture comprising an alkanoic acid, an alkylenating agent, and oxygen over a catalyst and under conditions effective to form a crude acrylate product. Preferably, the reaction mixture comprises from 0.5 wt % to 10 wt % oxygen. The crude acrylate product comprises acrylate product and alkylenating agent. The process further comprises the step of separating at least a portion of the crude product to form at least one alkylenating agent stream and at least one purified acrylate product stream. The purified acrylate product stream comprises acrylate product.
US08729297B2 Mannich condensation products useful as sequestering agents
The present invention is directed to Mannich condensation product sequestering agents or mixtures of Mannich condensation product sequestering agents for use in fuels and lubricating oils. The present invention is also directed to a process for preparing the Mannich condensation product sequestering agents. The present invention is also directed to a product formed by combining, under reaction conditions, a polyisobutyl-substituted hydroxyaromatic compound, an aldehyde, an amino acid or ester thereof, and an alkali metal base to form the Mannich condensation product sequestering agent. The present invention is also directed to a lubricating oil composition, a lubricating oil concentrate, a fuel composition, and a fuel concentrate having the Mannich condensation product sequestering agents of the present invention.
US08729296B2 Generation of peroxycarboxylic acids at alkaline pH, and their use as textile bleaching and antimicrobial agents
The present disclosure provides methods for generating percarboxylic acid compositions and/or peroxycarboxylic acid compositions formed external to a point of use in non-equilibrium reactions for use in certain bleaching and antimicrobial applications, in particular laundry applications. The compositions are generated external to a point of use, at alkaline pH levels, viz. greater than about pH 12, and optionally suitable for use with detergents and/or surfactants for synergistic bleaching efficacy. Methods of bleaching and/or disinfecting are further provided.
US08729294B2 Process for producing optically active 3-substituted-3-formyl-2-hydroxypropanoic acid compound
The present invention provides a production method of optically active 3-substituted-3-formyl-2-hydroxypropanoic acid compound (4), which includes a step of reacting glyoxylic acid compound (1-1) or (1-2) with aldehyde (2) in the presence of optically active pyrrolidine compound (3); wherein each symbol is as defined in the specification.
US08729292B2 Method for regeneration of raw ester
The invention relates to a raw ester of an esterification reaction catalyzed by a metal-containing esterification catalyst generated by a) mixing the raw ester at a temperature T of more than 100° C. under a pressure p that is equal to or greater than the vapor pressure of water at the temperature T with an aqueous base, b) relaxing the ester-base mixture and evaporating water, c) mixing the obtained fluid phase with water forming a water-in-oil emulsion, d) distilling water out of said emulsion and e) filtering the ester. Said method results in esters having low acid value and residues accrue in easily filterable form in the solid catalyst residues.
US08729286B2 Platinum compounds as treatment for cancers, and related methods, kits, and compositions
The present invention is a platinum(II) compound comprising a beta-diketonate ligand represented by the following general formula: Or general formula: wherein R1 and R2 are independently selected from the group consisting of alkyl optionally substituted, heteroalkyl optionally substituted, and aryl optionally substituted; R3 and R4 are independently selected from the group consisting of ammonia, an optionally substituted heterocycle including at least one nitrogen, and an optionally substituted amine, or R3 and R4 can be joined together to form a bidentate ligand Z and Y are independently selected from the group consisting of O and S, provided at least one of Z and Y is S; and X— is a counterion. These compounds are useful in the treatment of cancer.
US08729282B2 Process for the manufacture of a 1,2-epoxide
The invention relates to a process for the manufacture of a 1,2-epoxide by catalytic oxidation of a terminal olefin with hydrogen peroxide wherein the catalytic oxidation is performed in a biphasic system comprising an organic phase and an aqueous reaction medium, wherein a water-soluble manganese complex is used as oxidation catalyst, wherein a terminal olefin is used with a solubility at 20° C. of at least 0.01 to 100 g in 1 liter water, and wherein the molar ratio of terminal olefin to hydrogen peroxide is in the range of from 1:0.1 to 1:2.
US08729281B2 Production of hydroxymethylfurfural
The invention provides a process for making hydroxymethylfurfural comprising exposing a saccharide, e.g. glucose or fructose, to a metal complex of an N-heterocyclic carbene.
US08729280B2 Five crystal forms, methods of preparation, pharmaceutical compositions and applications of XLF-III-43
This invention discloses that the five crystal forms of XLF-III-43 can be used as crude drugs. The invention also relates to the preparation methods of the five crystal forms of XLF-III-43 as crude drugs, to the applications of the sterling of the five crystal forms of XLF-III-43 and mixed crystals in different proportions as medicinally active components to develop various kinds of medicines and compound medicines. In addition, this invention also relates to applying the crystal samples of XLF-III-43 as crude drugs to treat kidney dysfunction, cardiocerebral vessel diseases, hypertension, type II diabetic mellitus, complications of hypertension and diabetic mellitus, tumor, precancerosis, edema, and achieves therapeutic effects by enhancing blood drug levels resulted from effects of crystal forms in the processes of treating all kinds of diseases.
US08729276B2 Cyanine compound for labeling biomolecule and preparation method thereof
Disclosed are a novel cyanine compound, represented by the following Formula 1, for labeling biomolecules, and a method for preparing the same. wherein R1, R2, R3, R4, B, m and n are defined as above.
US08729273B2 Compounds effective as xanthine oxidase inhibitors, method for preparing the same, and pharmaceutical composition containing the same
The present invention relates to novel compounds which are effective as an inhibitor for xanthine oxidase, a process for preparing the same, and a pharmaceutical composition comprising a therapeutically effective amount of the same.
US08729270B2 Anti-cancer compounds, synthesis thereof, and methods of using same
Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to anti-cancer compounds, synthesis thereof, and methods of using same. Disclosed herein are various heterocyclic compounds and methods of using the novel anti-cancer compounds to inhibit the growth of a cancer cell, for instance a leukemia, non-small cell lung, central nervous system (CNS), skin, ovarian, renal, prostate, breast, or colon cancer cell. Other embodiments include methods of treating cancer in a subject, such as using the disclosed heterocyclic anti-cancer agents.
US08729266B2 Preparation of N-alkylated opiates by reductive amination
The present invention is directed to the reduction of an N-imine moiety or a hemiaminal moiety of a morphinan in the presence of a ruthenium, rhodium, or iridium asymmetric catalyst and a hydrogen source.
US08729263B2 1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions
The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
US08729262B2 Reverse-turn mimetics and method relating thereto
Conformationally constrained compounds that mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetic structures have utility over a wide range of fields, including use as diagnostic and therapeutic agents. Libraries containing the reverse-turn mimetic structures of this invention are also disclosed as well as methods for screening the same to identify biologically active members. The invention also relates to the use of such compounds for inhibiting or treating disorders modulated by Wnt-signaling pathway, such as cancer, especially colorectal cancer, restenosis associated with angioplasty, polycystic kidney disease, aberrant angiogenesis disease, rheumatoid arthritis disease, tuberous sclerosis complex, Alzheimer's disease, excess hair growth or loss, or ulcerative colitis.
US08729257B2 Hybrid lipid compounds based on pentaerythritol, intermediates, preparation methods and use thereof
This invention relates to a novel class of hybrid lipid compound based on pentaerythritol, their intermediates, preparation methods and uses thereof. Different kinds of functional groups such as alkyl chain, siloxane group, azobenzene, porphyrins, cholesterol, benzene ring and carboxyl were introduced into the four hydroxyl groups of pentaerythritol through chemical reaction to obtain the final hybrid lipid compounds based on pentaerythritol. Cerasomes prepared from such lipids have uniform size, silicate network surface, good stability and biocompatibility, and the leakage of drugs is not easy. The present liposome can be used as functional materials such as drugs or drug carriers, or used for optical storage and molecular devices, simulation, design and synthesis of artificial systems, nano-composite membrane materials and the removal of organic pollutants, etc., in addition, the preparation method of the present invention is simple, and it is easy for industrial production.
US08729256B2 Isomerization of sugars
Disclosed are processes for isomerizing saccharides. Also disclosed are processes for converting saccharides to furan derivatives. Also disclosed are processes for converting starch to furan derivatives.
US08729254B2 Derivative of glucose and vitamin F, compositions comprising it, uses and preparation process
An O-acyl product derived from glucose which may be obtained by partial or total esterification of glucose and of vitamin F, comprising a mixture of esters, for example, monoesters, of glucose and of at least one acid chosen from linoleic acid, oleic acid, palmitic acid and stearic acid, compositions, for example, cosmetic and pharmaceutical compositions, comprising this novel derivative, and their use for improving the condition of head hair and/or other hairs, and, for example, for reducing and/or impeding the loss of head hair and/or other hairs, and/or for inducing and/or stimulating hair growth, as well as a process for preparing O-acyl derivatives mainly in position 6 of glucose, comprising preparing a mixed anhydride by reacting a carboxylic acid with a trimethylacetyl halide, followed by reacting said mixed anhydride formed with glucose.
US08729251B2 Parallel preparation of high fidelity probes in an array format
The present invention provides massively parallel oligonucleotide synthesis and purification for applications that utilize large collections of defined high-fidelity oligonucleotides (e.g., from about 101 to about 105 different sequences, generally between 25-160 bases in length).
US08729246B2 Agent delivery system capable of selectively releasing an agent
The present invention provides a composition for selectively delivering an active agent to a portion of an organism. The composition comprises first and second polymer portions, having first and second functional groups attached as a side-chain thereto, respectively. The first and second functional groups form cross-links between the first and second polymer portions. The cross-links are capable of being broken by a substance of the organism, thereby resulting in release of the active agent. The composition provides a novel means for controlling the selective release of the active agent in the organism.
US08729245B2 Recombinant butyrylcholinesterases and truncates thereof
Isolated nucleic acids encoding polypeptides that exhibit butyrylcholinesterase (BChE) enzyme activity are disclosed, along with molecular criteria for preparing such nucleic acids, including codon optimization. Methods of preparing modified and/or truncated BChE molecules having selected properties, especially selective formation of monomers, are also described. Vectors and cells containing and/or expressing the nucleic acids are also disclosed.
US08729244B2 Method for purifying factor B
The invention relates to a method for purifying factor B, comprising the steps consisting in: (i) obtaining a blood plasma fraction containing factor B; (ii) subjecting the fraction obtained in step (i) to a heparin-like affinity chromatography; (iii) subjecting the factor B-enriched fraction obtained in step (ii) to a cation exchange chromatography; (iv) subjecting the factor B-enriched fraction obtained in step (iii) to an anion exchange chromatography, (v) eluting the factor B.
US08729237B1 Polypeptide adjuvant composition with thermostability and manufacture thereof
The present invention provides a polypeptide adjuvant composition with thermostability, which is designed from wild-type chicken interleikin-1β to construct a new chicken interleikin-1β, named CP-interleikin-1β. The CP-interleikin-1β having improved heat resistance keeps the original biological activity, and which helps to develop protein adjuvant with high efficiency and uses in medical application. The present invention also provides a method of manufacturing such polypeptide adjuvant composition.
US08729236B2 Selection and characterization of novel plant-derived recombinant human interferons with broad spectrum activity
Methods to derive novel hybrid type 1 interferons that are broadly active against highly pathogenic viruses of biodefense significance are described. Libraries of hybrid interferon genes were produced using gene shuffling, the proteins were expressed, and screened for activity against viruses of interest. Sequences of several broadly active hybrid interferons are described.
US08729226B2 Cancer therapy method
This invention describes a method for treating cancer by increasing the nuclear localization of the COMMD1 protein, which is associated with decreasing or blocking the proliferation of the cancer cell. The invention is also related to the use of agents that increase nuclear localization of the COMMD1 protein, in the manufacture of a medicament for cancer therapy. These agents can be peptides or proteins, among other compounds. The invention is also related to the optimization of a peptide, coming from the sequence HARIKPTFRRLKWKKYKGKFW, to increase the nuclear localization of the protein COMMD, and thus, to increase the antitumor effect of this peptide.
US08729225B2 Glycogen synthase kinase heteropolyligand polypeptide
The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands and polyligands that modulate GSK3 activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands and polyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands.
US08729222B2 Organic thin-film transistors
A thin-film transistor comprises a semiconducting layer comprising a semiconducting material selected from Formula (I) or (II): wherein X, R1, R2, R3, R4, R5 a, b, and n are as described herein. Semiconducting compositions of Formula (I) or (II) are also described.
US08729221B2 Conjugated copolymers chiral side chain for organic thin film transistors
Embodiments of the invention include polymers comprising a regioregular conjugated main chain section having an enantiopure or enantioenriched chiral side chain, as well as methods and materials for producing such polymers. Illustrative methods include regioselectively preparing a monomer that includes an enantiopure or enantioenriched chiral side group, and then reacting these monomers to produce a polymer that comprises a regioregular conjugated main chain section having an enantiopure or enantioenriched chiral side chains. In illustrative embodiments of the invention, the regioregular conjugated main chain section can contain a repeat unit that includes a dithiophene and a pyridine.
US08729216B2 Multifunctional sulfur-containing polymers, compositions thereof and methods of use
Disclosed are multifunctional sulfur-containing polymers that are the reaction products of a sulfur-containing diol, a polyol containing at least three hydroxyl groups per polyol molecule, and an aldehyde, a ketone, or a combination thereof. Sealant compositions comprising the multifunctional sulfur-containing polymers are also disclosed.
US08729213B2 Benzylated polyamine curing agents
A curing agent composition including at least one benzylated polyamine compound. The benzylated polyamine compound is a reaction product of a benzaldehyde compound or benzyl halide compound and a polyamine according to the following formula: H2N—CH2-A-CH2-NH2 where A is a phenylene group or a cyclohexylene group. A method for making the curing agent composition and an amine-epoxy composition are also disclosed.
US08729212B2 Polymer compositions and devices
Bioresorbable or biodegradable polymers formed from the monomers including sulphonyl diphenol, hydroxybenzoic acid and dicarboxylic acid. The dicarboxylic acid can include aliphatic dicarboxylic acid or a mixture of aliphatic dicarboxylic acid and aromatic dicarboxylic acid. Between 25 and 85 molar percent of the polymer is formed from the hydroxybenzoic acid, between 7.5 and 37.5 molar percent of the polymer is formed from the sulphonyl diphenol, and between 7.5 and 37.5 molar percent of the polymer is formed from the dicarboxylic acid. Polymers can be used for manufacturing fibers and composite devices.
US08729211B2 Perfluoropolyether urethane additives having (meth)acryl groups and hard coats
Fluorocarbon- and urethane-(meth)acryl-containing additives and hardcoats. The hardcoats are particularly useful as a surface layer on an optical device.
US08729210B2 Prepolymers based on di- or polyisocyanates and formamide-terminated low molecular weight compounds, processes for preparing the same and uses thereof
Prepolymers, which are accessible from formamides of low molecular weight di- or triamines (formamide-terminated low molecular weight compounds) and di- or polyisocyanates, of the general formula (II): X—[—N(CHO)—CO—NH—R1—NCO]n  (II) wherein X represents a linear or branched aliphatic, cycloaliphatic, heterocyclic and/or aromatic structural unit having 2 to 40 carbon atoms, and which is optionally further substituted and/or optionally comprises one or more heteroatoms, wherein R1 represents an organic radical which may optionally contain one or more heteroatoms and which may further contain one or more additional free isocyanate groups and/or one or more urethane, biuret, carbodiimide, isocyanurate, allophanate, iminooxadiazinedione and/or uretdione structural units, and wherein n≧2; processes for making the same; compositions containing the same; and uses thereof.
US08729208B2 Curable composition
A curable composition is provided. A cured product showing excellent light extraction efficiency, crack resistance, hardness, thermal shock resistance and adhesive strength after a curing, as well as showing excellent processability and workability is provided. Also, surface stickiness may be prevented in the cured product without causing turbidity etc.
US08729207B2 Types of polyester-modified organopolysiloxanes
The invention relates to new types of polyester-polysiloxane block copolymers, to processes for their preparation and to their use.
US08729205B2 Flowability improver for engineering plastics, thermoplastic resin compositions containing the same and molded articles of the compositions
A flowability improver for engineering plastics which comprises a polymer (A) comprising of 50 to 99.5% by mass of aromatic vinyl monomer units (a1), 0.5 to 50% by mass of (meth)acrylate monomer units (a2) having an ester group of phenyl or substituted phenyl group, and 0 to 40% by mass of other monomer units (a3) (with the proviso that the total of the units (a1) to (a3) is 100% by mass) and having a weight average molecular weight of 5000 to 150000. The flowability improver can improve engineering plastics in melt-flow characteristics (processability in molding) and chemical resistance without impairing the plastics in heat resistance, exfoliation resistance, and transparency.
US08729202B2 Biocompatible polymer compositions for dual or multi staged curing
The present invention provides a biocompatible polymer composition for use in biomedical applications comprising a base molecule, a linker molecule and at least one initiator compound, said base molecule having at least two differing functionalities, and said linker molecule having a functionality reactive with at least one functionality of said base molecule, the first of said at least two functionalities of said base molecule enabling a first curing stage of said polymer composition by reaction with said linker molecule, and the second and any further functionality of said base molecule enabling second and further curing stages of said polymer composition, said first, second and any further curing stages being capable of activation simultaneously or independently of each other as required.
US08729201B2 Process for polymerizing an olefin monomer and catalyst therefor
The present invention generally relates to a process that polymerizes an olefin monomer, and a precatalyst and catalyst useful in such process.
US08729198B2 Compositions comprising thiol-terminated polymers and sulfur-containing ethylenically unsaturated silanes and related cured sealants
Disclosed are compositions that include: a) a thiol-terminated polymer; and b) a sulfur-containing ethylenically unsaturated silane. Related products, such as sealants, that include polymers derived from such compositions, are also disclosed.
US08729197B2 Epoxy structural adhesive
Room temperature curing epoxy adhesives that show good adhesion to plastic substrates are described. The adhesives contain an epoxy resin component comprising a first epoxy resin and a second epoxy resin; a first amine curing agent having an equivalent weight of at least 50 grams per mole of amine equivalents; a second amine curing agent having an equivalent weight of no greater than 45 grams per mole of amine equivalents; an acetoacetoxy-functionalized compound; a metal salt catalyst; and a multifunctional acrylate.
US08729190B2 Particular water-absorbent agent having water-absorbent resin as main component
A particulate water-absorbent agent containing a polyacrylate salt-type water-absorbent resin. The agent has an absorption capacity without load of 28 g/g or higher and has a diffusion absorption index of 1.40 to 10.0 g/g min. The amount of water-soluble components in the agent, with stirring, is 15-60% by mass. The difference between this amount and the amount of water-soluble components, without stirring, is 15-50% by mass. Also disclosed is a method of making the above-identified agent.
US08729183B2 Silicone emulsions and method for producing same
Aqueous emulsions of high viscosity organopolysiloxanes can be prepared having a very low content of cyclic siloxanes by condensing low molecular weight alkoxy-functional organopolysiloxanes in aqueous emulsion with an alkylphosphate emulsifier and at least one selected polyoxyethylene non-ionic surfactant.
US08729180B2 Polycarbonate resin composition and formed product thereof
In a polycarbonate resin composition containing a polycarbonate resin and a polycarbosilane compound, the use of the polycarbosilane compound modifies the surface properties of the polycarbonate resin composition without adversely affecting the intrinsic characteristics of the polycarbonate resin, such as transparency, heat resistance, and mechanical properties, e.g., impact resistance. A polycarbonate resin composition containing 100 parts by mass of a polycarbonate resin, 0.001 to 1 part by mass of a metal salt compound, and 0.005 to 5 parts by mass of a polycarbosilane compound has significantly improved flame resistance and high transparency and causes markedly reduced outgassing and mold fouling, without losing impact resistance and heat resistance.
US08729176B2 Polyricinoleate composition and process for producing the same
A process is disclosed wherein ricinoleic acid from petroleum alternative vegetable castor oil that has a hydroxyl group at the 12-position or a derivative thereof (an ester or a hydrogenated compound thereof) is polymerized in the presence of a synthetic zeolite and an immobilized lipase at around normal temperature without using any harmful polymerization catalysts or organic solvents which can cause environmental pollution whereby a polyester useful in the industry that has a weight average molecular weight of 20,000 or more is obtained. This high-molecular weight polyester is crosslinked to give a crosslinked elastomer that is comparable to synthetic rubbers.
US08729175B2 Fluoroelastomer gels
Fluoroelastomeric gel having the following properties: appearance: transparent gelatinous solid; water content between 10% and 90% by weight; density between 1.1 and 2.1 g/cm3; said gel satisfies the following test: dried in a stove at 90° C. until a constant weight gives curable fluoroelastomers.
US08729174B2 Energy absorbing composition and impact and sound absorbing applications thereof
A substantially non-elastic incompressible composition, which substantially does not quickly self-level under standard operating conditions, includes: a suspending agent which reacts substantially as a solid when subjected to forces below a critical force, and which becomes substantially flowable when subjected to forces above said critical force; ceramic microparticulates dispersed within the suspending agent; flexible-walled microparticulates dispersed within the suspending agent; and celled macroparticulates dispersed within the suspending agent. The composition provides an incident energy absorbing property. The incident energy may include sound energy, and the microparticulates and macroparticulates may convert some of the sound energy into heat, or may diffract the sound energy.
US08729172B2 High performance engineering plastics and additive for use in engineering plastics
The present invention relates to engineering plastics having a high flame retardancy and a good compound processability, where the engineering plastics comprises microsilica as a flame retardant additive and as a processing aid.
US08729166B2 Polymer composition for microelectronic assembly
Embodiments in accordance with the present invention encompass polymer compositions that act as both a tack agent and a fluxing agent for the assembly of microelectronic components onto a variety of substrate materials. Such polymer compositions embodiments encompass a sacrificial polymer, a carrier solvent, a thermal acid generator and, optionally, formic acid.
US08729160B2 Admixture for hydraulic binder
A method includes adding at least one copolymer or a salt thereof acting as a plasticizer, blocking agent, or both a plasticizer and a blocking agent, to a calcium sulphate-based hydraulic binder. The copolymer includes an acrylic acid or a poly(oxy)alkylene copolymer.
US08729158B2 Fumed silica of controlled aggregate size and processes for manufacturing the same
The invention provides fumed silica comprising aggregates that have an aggregate size and a surface area that satisfy particular formulas relating aggregate size to surface area, as well as aggregates that exhibit particular viscosity, power law exponent index, and/or elastic modulus characteristics when dispersed in liquid media. The invention also provides processes of preparing such fumed silica by combining a silica precursor with a stream of combustible gas, combusting the stream, and producing a stream of combusted gas and fumed silica particles, wherein dopants are introduced, the time/temperature profile, or history, of the stream of combusted gas and fumed silica particles is adjusted to allow for post-quench aggregate growth, and/or additional silica precursor is introduced into the stream of combusted gas.
US08729156B2 Polyhydroxyalkanoate composition exhibiting improved impact resistance at low levels of impact modifier
The invention provides a composition exhibiting improved impact resistance at low levels of impact modifier. The composition comprises a polyhydroxyalkanoic acid and: (A) an elastomeric compound of core-shell type wherein the amount of (A) is from 0.1 to 6% by mass of the composition; and (B) and an olefinic copolymer comprising an ethylenic monomer bearing an epoxy function; wherein the amount of (B) is from 0.01 to 0.6% by mass of the composition and the mass ratio of (A)/(B) is from 85/15 to 99.5/0.5.
US08729153B2 Aqueous pigment dispersion for ink-jet ink and ink-jet ink composition
An aqueous pigment dispersion which contains C.I. Pigment Yellow 74, a styrene-acrylic-based resin with an acid number of 100 to 250, and a basic compound, wherein the styrene-acrylic-based resin includes at least styrene-based monomer units, acrylic acid monomer units, and methacrylic acid monomer units as component monomer units, and the weight average molecular weight of the resin is within a range from 7,000 to 15,000.
US08729151B2 Artificial marble and methods
There is provided an artificial marble that includes antimicrobial substance, wherein the antimicrobial substance comprises less that about 0.002% (dry weight) of the artificial marble composition.
US08729148B2 Photocurable dry film, method for preparing same, patterning method and film for protecting electric and electronic parts
Disclosed herein is a photocurable dry film including a structure having a photocurable resin layer sandwiched between a support film and a protective film, the photocurable resin layer being formed of a photocurable resin composition including ingredients (A) to (D):(A) a silicone skeleton-containing polymer compound having the repeating units represented by the following general formula (1) wherein X and Y, respectively, a divalent organic group represented by the following general formula (2) or (3) (B) a crosslinking agent selected from formalin-modified or formalin-alcohol-modified amino condensates and phenolic compound having on average two or more methylol groups or alkoxymethylol groups in one molecule; (C) a photoacid generator capable of generating an acid by decomposition with light having a wavelength of 190 to 500 nm; and (D) a solvent.
US08729141B2 Method for methanol synthesis using synthesis gas generated by combined reforming of natural gas with carbon dioxide
Disclosed is a method for methanol synthesis using synthesis gas obtained from reforming of natural gas with carbon dioxide. First, synthesis gas is obtained from steam carbon dioxide reforming of methane, in which steam reforming of natural gas is carried out simultaneously with carbon dioxide reforming of methane, by using a catalyst (Ni/Ce/MgAlOx, or Ni/Ce—Zr/MgAlOx) and processing condition capable of maintaining a predetermined ratio of carbon monoxide, carbon dioxide, and hydrogen [H2/(2CO+3CO2)=0.85-1.15]. Next, methanol synthesis is carried out by using the obtained synthesis gas and a catalyst system suitable for methanol synthesis with minimum byproduct formation (a catalyst system including a Cu—Zn—Al oxide containing CuO, ZnO, and Al2O3 at a predetermined ratio in combination with a cerium-zirconium oxide obtained by a sol-gel process). In addition, unreacted synthesis gas remaining after the operation of methanol synthesis is recycled efficiently to improve the carbon availability (methane and CO2 availability) and energy efficiency in the overall process.
US08729140B2 Process for regenerating a catalyst
A process for regenerating one or more deactivated cobalt comprising Fischer-Tropsch catalyst particle(s), comprising the steps of: (i) oxidizing the catalyst particle(s) at a temperature between 20 and 400° C.; (ii) treating the catalyst particle(s) for more than 5 minutes, (iii) drying the catalyst particle(s); and (iv) optionally reducing the catalyst particle(s) with hydrogen or a hydrogen comprising gas. This process may be preceded by a step in which Fischer-Tropsch product is removed from the catalyst particle(s). The treatment is performed using carbon dioxide and a liquid comprising ammonia.
US08729137B2 Cleansing bar
A cleansing bar comprising at least one member chosen from clay and talc, wherein a total amount of clay and talc is present in an amount that is greater than any other material in the cleansing bar, at least one cleanser chosen from soap and surfactant, and a binder present in an amount to structure the cleansing bar into a bar.
US08729135B2 Glutaraldehyde composition
This invention relates to a stabilized aqueous glutaraldehyde solution including 0.005% to 45% m/v, suitably 10% to 45% m/v solution of glutaraldehyde, an alcohol ethoxylate non-ionic surfactant, a buffer and a sufficient amount of a pH modifier to bring the pH of the solution to 6.0 to 8.5. The glutaraldehyde and the alcohol ethoxylate non-ionic surfactant are chemically bound together, suitably by complexing. These stable solutions can be stored for a period of at least six months without the glutaraldehyde polymerizing or the pH dropping below 5.0.
US08729132B2 Agomelatine hydrobromide hydrate and preparation thereof
The present invention relates to an agomelatine hydrobromide hydrate of formula I wherein X is Br, preparation and use thereof, and to pharmaceutical compositions containing it. The agomelatine hydrobromide hydrate obtained through the present method has significant increased solubility than agomelatine, and therefore is more suitable for manufacturing pharmaceutical formulations. In addition, the product enjoys higher stability and purity. Using the present method, product of high purity can be obtained through a simple process, free of any complicated steps.
US08729130B2 Methods of using novel solid forms of tacedinaline
Novel solid forms of tacedinaline (4-(acetylamino)-N-(2-aminophenyl)benzamide), including crystalline tacedinaline Forms A, B, and D, a novel crystalline tacedinaline TFA salt, and amorphous tacedinaline, are disclosed. Pharmaceutical compositions comprising crystalline tacedinaline Forms A, B, and D, the novel crystalline tacedinaline TFA salt, and/or amorphous tacedinaline, and methods of treating various conditions by administering those novel solid forms, are also disclosed.
US08729128B2 Lipoxin A4 protection for cornea endothelial cells
Lipoxin A4 and its analogs have been discovered to promote the cell proliferation of cornea endothelial cells, and thus promote the proper functioning of the labile tissue layer of cornea endothelial cells. These lipoxin compounds can be administered alone or in combination with other known compounds as a solution that can be topically administered to decrease the swelling of the cornea or maintain the clarity of the cornea. Lipoxin A4 or its analogs can also be combined with other known nutritive compounds to form a solution for storage of a cornea prior to transplantation.
US08729126B2 Use of pufas for treating skin inflammation
The present invention provides a compound which is a polyunsaturated fatty acid (PUFA) derivative of formula (I), or a pharmaceutically acceptable salt, or solvate thereof, for use in treating various skin disorders.
US08729125B2 Ophthalmic compositions and methods for treating eyes
Ophthalmic compositions including compatible solute components and/or polyanionic components are useful in treating eyes, for example, to relieve dry eye syndrome, to protect the eyes against hypertonic insult and/or the adverse effects of cationic species on the ocular surfaces of eyes and/or to facilitate recovery from eye surgery.
US08729116B2 Triazole compound having pesticidal activities
To provide a triazole compound which has remarkably excellent pesticidal activities. Optically active (+)-1-[2-fluoro-4-methyl-5-(2,2,2-trifluoroethylsulfinyl)phenyl]-5-amino-3-(trifluoromethyl)-1H-1,2,4-triazole represented by the following formula (I), which is obtainable by subjecting a racemic modification of 1-[2-fluoro-4-methyl-5-(2,2,2-trifluoroethylsulfinyl)phenyl]-5-amino-3-(trifluoromethyl)-1H-1,2,4-triazole to optical resolution:
US08729115B2 Valsartan derivatives carrying nitrogen oxide donors for the treatment of vascular and metabolic diseases
Nitrate esters and diazeniumdiolate derivatives of valsartanamide are described. They have valuable properties in the treatment of vascular and metabolic diseases.
US08729113B2 4,5-dihydro-oxazol-2yl derivatives
The invention relates to compounds of formula I wherein R1, R2, X, Y, and n are defined in the specification and to pharmaceutically acceptable acid addition salts thereof. The invention also provides pharmaceutical compositions and methods of manufacture of such compounds. The compounds are useful for the treatment of diseases related to the biological function of the trace amine associated receptors, which diseases are depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder, stress-related disorders, psychotic disorders, schizophrenia, neurological diseases, Parkinson's disease, neurodegenerative disorders, Alzheimer's disease, epilepsy, migraine, substance abuse and metabolic disorders, eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.
US08729112B2 Antimicrobial haloalkyl heterocycle compounds
This application describes compounds useful as anti-microbial agents, including as antibacterial, disinfectant, antifungal, germicidal or antiviral agents.
US08729110B1 2-thio-1,3,4-oxadiazoles derivatives as sphingosine-1 phosphate receptors modulators
The present invention relates to novel 2-thio-1,3,4-oxadiazoles derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
US08729106B2 Pesticidal compositions
A pesticidal composition comprising synergistically effective amounts of at least one anthranilamide compound represented by the formula (I) or its salt and other pesticide: wherein each of R1a and R1b which are independent of each other, is halogen; each of R2 and R3 is halogen, alkyl, haloalkyl, alkoxy, haloalkoxy or cyano; A is alkyl substituted by Y; Y is C3-4 cycloalkyl which may be substituted by at least one substituent selected from the group consisting of halogen, alkyl and haloalkyl; n is 0 or 1; and q is an integer of from 0 to 4; provided that R1a and R1b are not simultaneously chlorine nor bromine.
US08729105B2 Heteroarylmethyl amides
The present invention relates to compounds of the formula wherein A1, A2, A3 and R1 to R8 are defined in the description, and to pharmaceutically acceptable salts thereof, their manufacture, pharmaceutical compositions containing them and their use as medicaments for the treatment and/or prophylaxis of diseases which can be treated with HDL-cholesterol raising agents, such as particularly dyslipidemia, atherosclerosis and cardiovascular diseases.
US08729104B2 Diphenyl substituted alkanes as flap inhibitors
The instant invention provides compounds of formula I which are 5-lipoxygenase activating protein inhibitors. Compounds of formula I are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.
US08729101B2 1H-imidazole derivative having CB1, agonistic, CB1 partial agonistic or CB1 antagnistic activity
The present invention relates to a group of novel 1H-imidazole derivatives, to methods for the preparation of these compounds, and to pharmaceutical compositions containing one or more of these compounds as an active component. These 1H-imidazole derivatives are potent cannabinoid-CB1 receptor agonists, partial agonists or antagonists, useful for the treatment of psychiatric and neurological disorders, as well as and other diseases involving cannabinoid neurotransmission. The compounds have the general formula (I), wherein R and R1-R4 have the meanings given in the specification.
US08729092B2 Rosuvastatin enantiomer compounds
The invention discloses a method for the treatment of diseases, particularly those diseases characterized by diminished or aberrant cellular function, including AIDS, cancer, and Alzheimer's Disease. The method comprises administering a therapeutically effective amount of rosuvastatin enantiomer compounds in their (3R,5R), (3S,5R), or (3S,5S) configurations, or pharmaceutically acceptable salts thereof. Biologically-active rosuvastatin enantiomer compounds with (3R,5R), (3S,5R), and (3S,5S) stereochemistry are also disclosed.
US08729089B2 Pyrido(3,2-d)pyrimidines useful for treating viral infections
Pyrido(3,2-d)pyrimidine derivatives represented by the structural formula (I): wherein: R4 is hydrogen, and R1, R2 and R3 together provide a specific substitution pattern, pharmaceutical acceptable addition salts, stereochemical isomeric forms, N-oxides, solvates and pro-drugs thereof, are useful in the treatment of hepatitis C.
US08729087B2 Compositions and methods for inhibition of the JAK pathway
The invention encompasses compounds having formula I and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases are therapeutically useful.
US08729086B2 Fibrosis inhibitor
[Object] The main object of the present invention is to provide a fibrosis inhibitor.[Solving Means] The present invention relates to a fibrosis inhibitor containing the heterocyclic derivative represented by the following general formula (1) or a pharmaceutically acceptable salt thereof as an active ingredient; In the formula (1), R1 and R2 are the same or different and each represents an optionally substituted aryl; R3 and R4 are the same or different and each represents hydrogen atom or alkyl; R5 represents hydrogen atom, alkyl or halogen atom; Y represents N or N→O; A represents NR6, and R6 represents hydrogen atom, alkyl, etc.; D represents alkylene or alkenylene which is optionally substituted with hydroxy; E represents phenylene or a single bond; G represents O, S, etc.; and Q represents carboxy, alkoxycarbonyl, etc.
US08729083B2 Pyrazole compounds for controlling invertebrate pests
The present invention relates to pyrazole compounds of formulae I or II and the salts and N-oxides thereof, wherein A is a pyrazole radical of formulae A1, A2 or A3, wherein # denotes the binding site; R41, R42, R43, R51 are H, halogen, CN, NO2, C1-C10-alkyl and the like; R52, R53 are H, halogen, CN, NO2, C1-C10-alkyl, and the like; R61, R62, R63 are H, CN, NO2, C1-C10-alkyl, and the like; T is C(Rt) or N; U is C(Ru) or N; V is C(Rv) or N; W is C(Rw) or N; with the proviso that at least one of the groups T, U, V and W is N; Rt, Ru, Rv, Rw are H, halogen, C1-C4-alkyl and the like; X1 is S, O or NR1a, wherein R1a is selected H, C1-C10-alkyl and the like; X2 is OR2a, NR2bR2c, S(O)mR2d, wherein m is 0, 1 or 2, R2a is C1-C4-alkyl, C1-C4-haloalkyl and the like, R2b, R2c are H, C1-C4-alkyl, C1-C4-haloalkyl and the like, or R2b and R2c together with the nitrogen atom to which they are bound form a heterocycle, and R2d is C1-C4-alkyl, C1-C4-haloalkyl, C3-C6-cycloalkyl and the like; and R1 is H, CN, C1-C10-alkyl and the like. The present invention further relates to a method for controlling invertebrate pests, to a method for protecting plant propagation material and/or the plants which grow therefrom, to plan propagation material, comprising at least one compound according to the present invention, to a method for treating or protecting an animal from infestation or infection by parasites and to an agricultural composition containing at least one compound according to the present invention.
US08729081B2 Compositions and methods for treating alcohol use disorders, pain and other diseases
The present invention provides compounds which antagonize epsilon protein kinase C (PKCε). These compounds have a structural formula (Ia), (Ic) or (II). The present invention also provides pharmaceutical compositions containing these compounds and methods of treating various diseases, conditions, and/or symptoms by using these compounds.
US08729080B2 Cancer therapy
The subject invention provides for cancer therapy.
US08729076B2 Secondary 8-hydroxyquinoline-7-carboxamide derivatives
The present invention provides new secondary 8-hydroxyquinoline-7-carboxamide derivatives of general formula (I) and pharmaceutically acceptable salts thereof. These compounds are useful as antifungal agents. Specifically, these compounds were tested against Tricophyton Rubrum, Tricophyton Mentagrophytes, Aspergillus Niger and Scopulariopsis Brevicaulis. Many of these compounds are active against Candida species such as Candida Albicans and Candida Glabrata.
US08729071B2 Iminothiadiazine dioxide compounds as BACE inhibitors, compositions and their use
In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (I): (I) and include stereoisomers thereof, and pharmaceutically acceptable salts of said compounds stereoisomers, wherein each of R1, R2, R3, R4, R5, R9, ring A, ring B, m, n, p, -L1-, L2-, and L3- is selected independently and as defined herein. The novel iminothiadiazine dioxide compounds of the invention have surprisingly been found to exhibit properties which are expected to render them advantageous as BACE inhibitors and/or for the treatment and prevention of various pathologies related to β-amyloid (Aβ) production. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use in treating pathologies associated with amyloid beta (Aβ) protein, including Alzheimers disease, are also disclosed.
US08729069B2 Tetrahydropyridine, tetrahydroazepine, and dihydropyrrole derivatives for inflammation and immune-related uses
The invention relates to compounds of structural formula (Ia): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein X1, X2, X3, X4, X6, X10, R1, Y, Z, L, and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
US08729064B2 Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors
Disclosed are compounds, compositions and methods for treating diseases, syndromes, conditions and disorders that are affected by the inhibition of MGL, including pain. Such compounds are represented by Formula (I) as follows: wherein R1, W and are defined herein.
US08729062B2 Benzyl azetidine derivatives as sphingosine 1-phosphate (S1P) receptor modulators
The present invention relates to novel benzyl azetidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
US08729058B2 Methods and compositions for treating and preventing viral infections
A method of treating or preventing a systemic viral infection in a mammal by administering a pharmaceutically acceptable composition selected from the group consisting of squalamine, an active isomer thereof, and an active analogue thereof, via a dosing regimen that delivers effective antiviral concentrations of squalamine. Also compositions for achieving the systemic antiviral effect.
US08729057B2 Testosterone gel and method of use
The present invention relates to an improved transdermal hydroalcoholic testosterone gen formulation that provides, among other things, a desirable pharmacokinetic hormone profile, and methods of use.
US08729056B2 Preventive and/or therapeutic agent of hand-foot syndrome
The agent for the prevention and/or treatment of Hand-Foot Syndrome comprising a compound with anticholinergic activity can be provided. The agent for the prevention and/or treatment of Hand-Foot Syndrome comprising a compound with anticholinergic activity can be safely administered to the patients with Hand-Foot Syndrome, and has shown the superior preventive and/or treatment effect against Hand-Foot Syndrome.
US08729054B2 3-desoxy-2-methylene-vitamin D analogs and their uses
This invention discloses 3-desoxy-2-methylene-vitamin D analogs, and specifically (20S)-3-desoxy-1α,25-dihydroxy-2-methylene-vitamin D3 and (20R)-3-desoxy-1α,25-dihydroxy-2-methylene-vitamin D3 as well as pharmaceutical uses therefor. These compounds exhibit relatively high binding activity and pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to monocytes thus evidencing use as anti-cancer agents especially for the treatment or prevention of osteosarcoma, leukemia, colon cancer, breast cancer, skin cancer or prostate cancer. These compounds also exhibit relatively high calcemic activity evidencing use in the treatment of bone diseases.
US08729052B2 Composition for the prevention and treatment of alopecia, or for hair growth
Disclosed is a composition for prevention and treatment of alopecia or for hair growth, comprising a phytosphingosine-1-phosphate derivative or a pharmaceutically acceptable salt thereof as an active ingredient. Also, a medicine comprising the composition and a quasi-drug comprising the composition are provided.
US08729051B2 Tri- and tetra-oligo-saccharides suitable as agglutination agents for enteric pathogens
Compositions which include a homotrimer, heterotrimer, homotetramer, and/or heterotetramer of a component such as pentose, hexose, an L or D isomer of a pentose or hexose, a β-form of a pentose or hexose, oxidized derivatives and mixtures of such compounds are disclosed as agglutination agents. The disclosed compositions are useful for agglutination of enteric pathogens and may be used for selectively controlling and regulating the microbial ecosystem in the gastrointestinal tract of a subject.
US08729050B2 Method for prevention and treatment of reflux injury in the aerodigestive tract and laryngopharynx caused by pepsin
A method for treating or preventing disorders, diseases, and symptom of reflux, that is laryngopharyngeal reflux (LPR), in the laryngopharynx caused by pepsin comprises orally administering to the laryngopharynx of a patient an effective amount of cellulose powder. A method for treating or preventing damage to the lining membranes of at least some of the aerodigestive tract, the damage caused by pepsin, comprises coating at least some of the lining membranes with an effective amount of a cellulose powder. Upon inhalation of the powder, the powder coats the lining membranes. Upon coating the lining membranes, the powder becomes a gel. The gel prevents the pepsin from binding with the lining membranes, thereby preventing damage caused by pepsin in laryngopharyngeal reflux or in extra-esophageal reflux.
US08729049B2 Leaven-based mixture
An embodiment is a mixture obtainable by a process comprising the following steps: a) adding a culture comprising sprouted rye grains and water to a rye fine or coarse meal and subjecting the mixture to a process of heating to 30-34° C. within 3 to 5 hours, a strong maltose formation being initiated from enzymatic reactions; b) followed by a further addition of rye fine or coarse meal, water and a bacteriological inoculum from the group of heterofermentative lactic-acid bacteria; c) acidifying the mixture until the metabolic activity of the microorganisms ceases, and optionally pasteurizing at 90-95° C.; d) separating the mixture by centrifugation into a solution and a precipitate, after which the solution is optionally filtered at least once.
US08729048B2 Methods and materials for assessing responsiveness to PARP inhibitors and platinating agents
This document provides methods and materials involved in assessing responsiveness to PARP inhibitors and platinating agents. For example, methods and materials for using levels of non-homologous end-joining pathway members (e.g., artemis mRNA or polypeptide levels, Ku80 mRNA or polypeptide levels, or DNA-PKcs mRNA or polypeptide levels) to determine if cancer cells that are homologous recombination-deficient are likely to be susceptible or resistant to PARP inhibitors and platinating agents are provided.
US08729039B2 Use of inhibitory oligonucleotides to treat autoimmune disease
The invention consists of oligonucleotides which inhibit the immunostimulatory activity of ISS-ODN (immunostimulatory sequence oligodeoxynucleotides) as well as methods for their identification and use. The oligonucleotides of the invention are useful in controlling therapeutically intended ISS-ODN adjuvant activity as well as undesired ISS-ODN activity exerted by recombinant expression vectors, such as those used for gene therapy and gene immunization. The oligonucleotides of the invention also have anti-inflammatory activity useful in reducing inflammation in response to infection of a host with ISS-ODN containing microbes, in controlling autoimmune disease and in boosting host Th2 type immune responses to an antigen. The invention also encompasses pharmaceutically useful conjugates of the oligonucleotides of the invention (including conjugate partners such as antigens and antibodies).
US08729038B2 Down regulation of the gene expression by means of nucleic acid-loaded virus-like particles
The present invention relates to compositions of virus-like particles for the introduction of RNA-interference (RNAi-) inducing molecules into eukaryotic cells and methods for the cell type-specific transduction of a plurality of eukaryotic cells with RNAi-inducing molecules. The present invention furthermore relates to methods for a diagnosis, prevention and/or treatment of diseases or disease states associated with an increased expression rate of at least one endogenous gene, and/or with the undesired expression of at least one endogenous gene and/or foreign nucleic acids, in particular viral nucleic acids.
US08729034B2 Pharmaceutical composition having virucidal and spermicidal activity
Acaciaside-B (Ac-B) has emerged as a prospective candidate molecule for prevention of HIV infection along with potential for use as/in vaginal contraceptive/formulation. It possesses anti-HIV property at a tolerably low concentration, is non-mutagenic and does not harm the niche of Lactobacilli. Thus Ac-B appears to be a superior ingredient for formulations of a chemical barrier against HIV-1 infection wherein its spermicidal property is superfluous.
US08729032B2 Self-assembling peptide and peptide gel with high strength
Provide are a peptide gel with practically sufficient mechanical strength and a self-assembling peptide capable of forming the peptide gel. The self-assembling peptide is formed of the following amino acid sequence: a1b1c1b2a2b3db4a3b5c2b6a4 where: a1 to a4 each represent a basic amino acid residue; b1 to b6 each represent an uncharged polar amino acid residue and/or a hydrophobic amino acid residue, provided that at least five thereof each represent a hydrophobic amino acid residue; c1 and c2 each represent an acidic amino acid residue; and d represents a hydrophobic amino acid residue.
US08729031B2 Compounds
Compounds of formula (IV) and pharmaceutical compositions comprising the same are described, wherein X1 and X2, R3, L, Ar1, p and Z have the values disclosed herein.
US08729025B2 Methods for altering MRNA splicing and treating familial dysautonomia by administering kinetin, benzyladenine, and tocotrienols
This invention relates to methods for altering the splicing of mRNA in cells. In particular, this invention also relates to methods for increasing the ratio of wild type to misspliced forms of mRNA and corresponding encoded proteins in cells possessing a mutant gene encoding either the i) misspliced mRNA corresponding to the mutant protein or ii) a component in the splicing machinery responsible for processing the misspliced mRNA. In addition, this invention relates to treating individuals having a disorder associated with a misspliced mRNA, such as Familial Dysautonomia or Neurofibromatosis 1, by administering to such an individual a cytokinin such as kinetin.
US08729022B2 Stabilised solid compositions of factor VII polypeptides
The invention relates to chemically as well as physically stable compositions comprising Factor VII or a Factor VII-related polypeptide such that these compositions can be stored, handled and used at room temperature.
US08729016B2 Oral insulin therapies and protocol
Methods for treating impaired glucose tolerance and early and late stage diabetes in mammals, for prophylactically sparing β-cell function, aiding in preventing β-cell death, preventing the onset of overt diabetes in a mammal with type 2 diabetes, treating the current level of glycemic control dysfunction of a mammal with impaired glucose tolerance or diabetes, comprising orally administering insulin and a delivery agent that facilitates insulin absorption from the gastrointestinal tract at the time of or shortly before mealtime, e.g., within about 10 minutes prior to ingestion of a meal, on a chronic basis. The methods also comprise, in addition to administering a rapid-acting insulin to provide a first insulin peak, administering a slow acting insulin to provide a second insulin peak occurring at a later time but of a longer duration. These methods achieve improved glycemic control without the risks of hypoglycemia, hyperinsulinemia and weight gain and the need for frequent blood glucose monitoring that are normally associated with insulin therapy.
US08729015B2 Solid lipid microcapsules containing growth hormone inner core microparticles
The invention relates to growth hormone (GH) formulations having sustained-release properties, in particular human growth hormone (hGH) and methods for their preparation. The growth hormone formulations can be manufactured without denaturing of the protein and can conveniently be administrated to the person in need thereof by using a conventional syringe via a needle having a small diameter.
US08729013B2 Methods of inhibiting staphylobactin-mediated iron uptake in S. aureus
Methods of inhibiting S. aureus are provided. The methods include inhibition of polypeptides involved in the transport of the siderophore, staphylobactin.
US08729012B2 Controllable assembly and disassembly of nanoparticle systems via protein and DNA agents
The invention relates to the use of peptides, proteins, and other oligomers to provide a means by which normally quenched nanoparticle fluorescence may be recovered upon detection of a target molecule. Further, the inventive technology provides a structure and method to carry out detection of target molecules without the need to label the target molecules before detection. In another aspect, a method for forming arbitrarily shaped two- and three-dimensional protein-mediated nanoparticle structures and the resulting structures are described. Proteins mediating structure formation may themselves be functionalized with a variety of useful moieties, including catalytic functional groups.
US08729007B2 Acidic laundry detergent compositions comprising alkyl benzene sulfonate
An acidic laundry detergent composition comprising less than about 20% of a surfactant system comprising surfactants selected from the group consisting of anionic surfactants, nonionic surfactants, cationic surfactants and mixtures thereof, wherein the surfactant system has a Hydrophilic Index of greater than or equal to about 9.00 and an organic acidulant at a level such that the ratio of surfactant system to organic acidulant is less or equal to about 3.0 and an alkaline neutralizer added in an amount necessary to raise the neat pH of the detergent composition above or equal to about 2.5 but no higher than or equal to about 3.0.
US08729003B2 Processes and compositions for cleaning mixing devices to improve polycarbonate production
Processes and compositions for cleaning mixing devices are disclosed that improve the production and quality of polycarbonate resins subsequently produced in the mixing device, while reducing the time needed for cleaning and/or change over. A cleaning mixture comprising polycarbonate resin pellets coated with an alkyl aryl sulfonate salt aqueous solution are used to purge the mixing device.
US08729000B2 Single use multi-phase care system
A convenient single use multi-phase care system including multiple formulations can be packaged in one dispensing unit. The multi-phase care system is capable of separately dispensing one of the multiple formulations at a time in a sequential order to allow the consumer to dispense a daily care regimen one step at a time. In one embodiment, the daily care regimen is a multi-phase skin care system. In another embodiment, the daily care regimen is a multi-phase hair care system.
US08728995B2 Process for the preparation of polyalkenyl succinic anhydrides
A polyalkenyl succinic anhydride is prepared with low amounts of resinous or chlorinated byproducts in a two-step process whereby a polyalkene is first reacted with an unsaturated organic acid in a thermal ene reaction, followed with exposure to a gaseous halogen in presence of an additional amount of the unsaturated organic acidic reagent. The foregoing process produces a polyisobutenyl succinic anhydride having a high ratio of succinic anhydride functional groups to polyisobutenyl backbone groups. Such a polyisobutenyl succinic anhydride is particular suitable for the production of oil-soluble hydrocarbyl succinimides that have good dispersant properties when added to lubricating oil compositions.
US08728994B2 Oil type lubricant for forging, forging method and spray apparatus
An oil type lubricant for forging, which is featured in that the flash point thereof is confined to the range of 70-170° C., the kinematic viscosity thereof at 40° C. is confined to the range of 4-40 mm2/s and that it contains neither water nor an emulsifier. A forging method and a spray apparatus wherein the above-described oil type lubricant is used.
US08728993B2 Inert wear resistant PTFE-based solid lubricant nanocomposite
A PTFE-based composite material includes a PTFE major phase filled with a metal oxide minor phase. The major phase is intermixed with the metal oxide minor phase, wherein the minor phase includes a plurality of irregularly shaped metal oxide nanoparticles. The irregularly shaped nanoparticles provide substantial reductions in steady state wear rate over otherwise similar nanocomposites. The metal oxide can comprise aluminum oxide.
US08728992B2 Grease composition and bearing
The invention provides a grease composition containing a thickener, a base oil and an antistatic agent, where the antistatic agent includes at least one selected from the group consisting of Li(CF3SO2)2N and Li(CF3SO2)3C; and a mechanical part where the above-mentioned grease composition is packed. The composition of the invention shows satisfactory results in the antistatic properties and the acoustic property.
US08728990B2 Phosphate ester oil gellant
A composition and method of fracturing a subterranean formation. The composition includes: about 0.25 wt. % to about 3.0 wt. %, based on a weight of the hydrocarbon liquid, of a mixture of phosphate esters, said esters selected from the group consisting of: monoester PO(OR1)(OH)2, PO(OR2)(OH)2; diester PO(OH)(OR1)m(OR2)2−m where m=0, 1, or 2; triester PO(OH)(OR1)n(OR2)3−n where n=0, 1, 2 or 3; and phosphoric acid H3PO4 wherein R1 and R2 each have 2 to 18 carbon atoms; and about 0.2 wt. % to about 1.0 wt. %, based on the weight of the hydrocarbon liquid, of an acidic polynuclear aluminum compound having an Al:Cl mole ratio ranging from about 1.40:1 to about 2.2:1. The composition is added to a hydrocarbon liquid to fracture the subterranean formation with this hydrocarbon liquid. The hydrocarbon liquid containing the composition exhibits a substantially constant viscosity.
US08728989B2 Oil based concentrated slurries and methods for making and using same
New hydrocarbon based slurry compositions and drilling, fracturing, completion and production fluids including the hydrocarbon based slurry composition are disclosed, where the composition includes a hydrocarbon soluble polymer adapted to decrease particle settling rates of particulate materials present in the fluids and in the case of fluids that include hydratable materials to increase hydration properties of such materials.
US08728983B2 Phage display vector
The invention relates to a minimized phage display vector comprising at least a cloning cassette, a phage display cassette and a bacterial cassette, said cloning cassette comprising a nucleic acid sequence encoding a polypeptide corresponding at least to the intra-domain loop of a constant domain of an antibody. It also relates to their uses for the production of libraries of phages, each phage expressing on its surface a binding protein to be screened for its capacity to bind a binding partner.
US08728981B2 Collection and methods for its use
The present disclosure enables collections of variable heavy chain and variable light chain pairs comprising, in part, germline protein sequences that are pre-selected for functional properties relevant to developability, wherein the collections may be used to select against any antigen using, for example, phage display.
US08728978B2 Biocide compositions (IV)
Suggested are biocide compositions, comprising (a) esters based on ketocarboxylic acids, (b) biocides, and optionally (c) oil components or co-solvents and/or (d) emulsifiers. The compositions exhibit an improved stability even if stored at temperatures between 5° and 40° C. over a longer period.
US08728977B2 Herbicidal combinations comprising tefuryltrione for use in rice crops
A description is given of herbicidal compositions comprising A) tefuryltrione and B) at least one additional herbicide. These compositions exhibit a superior action in comparison with the herbicides applied separately.
US08728975B2 Method of producing a catalyst body containing uranium oxide as active component
A method for producing a uranium oxide catalyst body includes the following steps: UO2+x powder, with x≦0.7, having a purity of at least 50% is sintered in a first sintering process to obtain a UO2+y intermediate, where y≦0.25. Then the UO2+y intermediate is oxidized with oxygen and converted in the process into a U3O8−z powder, with z≦1. The U3O8−z powder is pressed to form a blank having a shape that corresponds with the catalyst body to be produced. The blank is sintered in a second sintering process at a temperature of at least 900° C. in an oxygen-containing sintering atmosphere.
US08728970B2 Catalyst component for the polymerization of olefins
A solid catalyst component comprising the product of a process comprising (a) reacting a magnesium alcoholate of formula Mg(OR1)(OR2) compound, in which R1 and R2 are identical or different and are each an alkyl radical having 1 to 10 carbon atoms, with titanium tetrachloride carried out in a hydrocarbon at a temperature of 50-100° C., (b) subjecting the reaction mixture obtained in (a) to a heat treatment at a temperature of 110° C. to 200° C. for a time ranging from 3 to 25 hours (c) isolating and washing with a hydrocarbon the solid obtained in (b), said solid catalyst component having a Cl/Ti molar ratio higher than 2.5.
US08728964B2 Glass composition with low coefficient of thermal expansion, and glass fiber produced from same
The present disclosure relates to a glass composition having a low thermal expansion coefficient, specifically, a glass composition comprising about 55 to less than 64 weight percent of silicon oxide, about 15 to about 30 weight percent of aluminum oxide, about 5 to about 15 weight percent of magnesium oxide, about 3 to about 10 weight percent boron oxide, about 0 to about 11 weight percent calcium oxide, and about 0 to about 2 weight percent of alkali oxide, the remainder being trace compounds of less than about 1 weight percent, is provided. Glass fibers and composite articles formed therefrom are also provided.
US08728963B2 Optical glass
An optical glass that is an oxide glass having a very high refractive index in spite of its low-dispersion property, having excellent glass stability and having less susceptibility to coloring.
US08728959B2 Textile digital band and fabricating method thereof
The present invention relates to a textile digital band which is capable of providing a high-speed communication path with surrounding computing devices, through easy and convenient attachment thereof to a conventional garment, and a fabrication method thereof. For this purpose, disclosed herein is a textile digital band comprising a plurality of warps formed parallel to each other in the first direction, and a plurality of wefts formed parallel to each other in the second direction perpendicular to the first direction, wherein the warp includes at least one digital yarn through which electrical currents can flow.
US08728958B2 Gap fill integration
Novel gap fill schemes involving depositing both flowable oxide films and high density plasma chemical vapor deposition oxide (HDP oxide) films are provided. According to various embodiments, the flowable oxide films may be used as a sacrificial layer and/or as a material for bottom up gap fill. In certain embodiments, the top surface of the filled gap is an HDP oxide film. The resulting filled gap may be filled only with HDP oxide film or a combination of HDP oxide and flowable oxide films. The methods provide improved top hat reduction and avoid clipping of the structures defining the gaps.
US08728956B2 Plasma activated conformal film deposition
Methods of depositing a film on a substrate surface include surface mediated reactions in which a film is grown over one or more cycles of reactant adsorption and reaction. In one aspect, the method is characterized by the following operations: (a) exposing the substrate surface to a first reactant in vapor phase under conditions allowing the first reactant to adsorb onto the substrate surface; (b) exposing the substrate surface to a second reactant in vapor phase while the first reactant is adsorbed on the substrate surface; and (c) exposing the substrate surface to plasma to drive a reaction between the first and second reactants adsorbed on the substrate surface to form the film.
US08728955B2 Method of plasma activated deposition of a conformal film on a substrate surface
A method of depositing a film on a substrate surface includes providing a substrate in a reaction chamber; selecting a silicon-containing reactant from a precursor group consisting of di-tert-butyl diazidosilane, bis(ethylmethylamido)silane, bis(diisopropylamino)silane, bis(tert-butylhydrazido)diethylsilane, tris(dimethylamido)silylazide, tris(dimethylamido)silylamide, ethylsilicon triazide, diisopropylaminosilane, and hexakis(dimethylamido)disilazane; introducing the silicon-containing reactant in vapor phase into the reaction chamber under conditions allowing the silicon-containing reactant to adsorb onto the substrate surface; introducing a second reactant in vapor phase into the reaction chamber while the silicon-containing reactant is adsorbed on the substrate surface, and wherein the second reactant is introduced without first sweeping the silicon-containing reactant out of the reaction chamber; and exposing the substrate surface to plasma to drive a reaction between the silicon-containing reactant and the second reactant on the substrate surface to form the film.
US08728954B2 Method of manufacturing semiconductor device, substrate processing apparatus, and recording medium
A method of manufacturing a semiconductor device includes forming a thin film containing a specific element, oxygen, carbon, and nitrogen by performing a cycle a predetermined number of times. The cycle includes supplying a specific element-containing gas, supplying a carbon-containing gas, supplying an oxidizing gas, and supplying a nitriding gas. The act of supplying the nitriding gas is performed before the act of supplying the specific element-containing gas, and the act of supplying the carbon-containing gas and the act of supplying the oxidizing gas are not performed until the act of supplying the specific element-containing gas is performed.
US08728953B2 Method and apparatus for processing a semiconductor workpiece
A method of processing a semiconductor workpiece includes placing a back surface of the workpiece on a workpiece support in a chamber so that the front surface of the workpiece faces into the chamber for processing, and the back surface is in fluid communication with a back region having an associated back gas pressure. The method further includes performing a workpiece processing step at a first chamber pressure Pc1 and a first back pressure Pb1, wherein Pc1 and Pb1 give rise to a pressure differential, Pb1−Pc1, and performing a workpiece cooling step at a second chamber pressure Pc2 and a second back pressure Pb2, wherein Pc2 and Pb2 are higher than Pc1 and Pb1, respectively.
US08728952B2 Coating method of an alignment film
Provided is a coating method of an alignment film, including: providing a board, having a substrate, the substrate forming an alignment liquid coating area thereon; forming a barrier structure around the alignment liquid coating area; coating an alignment liquid in the alignment liquid coating area, wherein the barrier structure blocks the alignment liquid to diffuse outside the alignment liquid coating area; and curing the alignment liquid to form an alignment film. The present invention may assure that the formed alignment film can not affect other areas adjacent to the alignment liquid coating area.
US08728950B2 Coating method, and organic electroluminescence element
Disclosed are a coating method of forming a coating with a stable thickness from a coating solution with a low viscosity employing a slit-type die coater and an organic electroluminescence element prepared employing the coating method. The coating method employing a slit-type die coater comprises the steps of allowing a lip tip of the slit-type die coater to bring close to the substrate to form a coating solution bead between the lip tip and the substrate, and coating on the substrate a coating solution ejected from a slit outlet at the lip tip while relatively moving the slit-type die coater and the substrate, thereby forming at least two coating layers in the stripe shape, featured in that the lip tip has at least one groove in the coating region in the coating width direction, and a pressure at the slit outlet of the coating solution of the bead is negative or zero.
US08728945B2 Method for patterning sublithographic features
A method of uniformly shrinking hole and space geometries by forming sidewalls of an ALD film deposited at low temperature on a photolithographic pattern.
US08728934B2 Systems and methods for producing flat surfaces in interconnect structures
Methods and apparatus for forming a semiconductor device are provided which may include any number of features. One feature is a method of forming an interconnect structure that results in the interconnect structure having a co-planar or flat top surface. Another feature is a method of forming an interconnect structure that results in the interconnect structure having a surface that is angled upwards greater than zero with respect to a top surface of the substrate. The interconnect structure can comprise a damascene structure, such as a single or dual damascene structure, or alternatively, can comprise a silicon-through via (TSV) structure.
US08728933B1 Laser cutting and chemical edge clean for thin-film solar cells
A method of kerf formation and treatment for solar cells and semiconductor films and a system therefor are described. A semiconductor film is backed by a first metal layer and topped by a second metal layer. A reference feature is defined on the film. An ultraviolet laser beam is aligned to the reference feature. A kerf is cut along the reference feature, using the ultraviolet laser beam. The beam cuts through the second metal layer, through the film and through the first metal layer. Cutting leaves debris deposited on walls of the kerf. The debris is cleaned off of the walls, using an acid-based solvent. In the case of solar cells, respective first terminals of the solar cells are electrically isolated by the cleaned kerf, and respective negative terminals of the solar cells are electrically isolated by the cleaned kerf.
US08728931B2 Multi-layer barrier layer for interconnect structure
A method for forming an interconnect structure includes forming a recess in a dielectric layer of a substrate. An adhesion barrier layer is formed to line the recess. A first stress level is present across a first interface between the adhesion barrier layer and the dielectric layer. A stress-reducing barrier layer is formed over the adhesion barrier layer. The stress-reducing barrier layer reduces the first stress level to provide a second stress level, less than the first stress level, across a second interface between the adhesion barrier layer, the stress-reducing barrier layer, and the dielectric layer. The recess is filled with a fill layer.
US08728927B1 Borderless contacts for semiconductor transistors
Embodiments of the invention include methods of forming borderless contacts for semiconductor transistors. Embodiments may include providing a transistor structure including a gate, a spacer on a sidewall of the gate, a hard cap above the gate, a source/drain region adjacent to the spacer, and an interlevel dielectric layer around the gate, forming a contact hole above the source/drain region, forming a protective layer on portions of the hard cap and of the spacer exposed by the contact hole; deepening the contact hole by etching the interlevel dielectric layer while the spacer and the hard cap are protected by the protective layer, so that at least a portion of the source/drain region is exposed by the deepening of the contact hole; removing the protective layer; and forming a metal contact in the contact hole.
US08728926B2 Semiconductor device and method for manufacturing a semiconductor device
The present invention discloses a method for manufacturing a semiconductor device. According to the method provided by the present disclosure, a dummy gate is formed on a substrate, removing the dummy gate to form an opening having side walls and a bottom gate, a dielectric material is formed on at least a portion of the sidewalls of the opening and the bottom surface of the opening, and a pre-treatment is performed to a portion of the dielectric material layer on the sidewalls of the opening, and thus the properties of the dielectric material is changed, and then the pre-treated dielectric material on the sidewalls of the opening is removed by a selective process. The semiconductor device manufactured by using the method of the present disclosure is capable of effectively reducing parasitic capacitance.
US08728925B2 Method and structure for work function engineering in transistors including a high dielectric constant gate insulator and metal gate (HKMG)
Adjustment of a switching threshold of a field effect transistor including a gate structure including a Hi-K gate dielectric and a metal gate is achieved and switching thresholds coordinated between NFETs and PFETs by providing fixed charge materials in a thin interfacial layer adjacent to the conduction channel of the transistor that is provided for adhesion of the Hi-K material, preferably hafnium oxide or HfSiON, depending on design, to semiconductor material rather than diffusing fixed charge material into the Hi-K material after it has been applied. The greater proximity of the fixed charge material to the conduction channel of the transistor increases the effectiveness of fixed charge material to adjust the threshold due to the work function of the metal gate, particularly where the same metal or alloy is used for both NFETs and PFETs in an integrated circuit; preventing the thresholds from being properly coordinated.
US08728920B2 Schottky diode with control gate for optimization of the on state resistance, the reverse leakage, and the reverse breakdown
A Schottky diode optimizes the on state resistance, the reverse leakage current, and the reverse breakdown voltage of the Schottky diode by forming an insulated control gate over a region that lies between the metal-silicon junction of the Schottky diode and the n+ cathode contact of the Schottky diode.
US08728919B2 Non-volatile semiconductor storage device and method of manufacturing the same
A non-volatile semiconductor storage device includes a plurality of memory strings each having a plurality of electrically rewritable memory cells connected in series. Each of the memory strings comprising: a first semiconductor layer including a columnar portion extending in a vertical direction with respect to a substrate; a plurality of first conductive layers formed to surround side surfaces of the columnar portions via insulation layers, and formed at a certain pitch in the vertical direction, the first conductive layers functioning as floating gates of the memory cells; and a plurality of second conductive layers formed to surround the first conductive layers via insulation layers, and functioning as control electrodes of the memory cells. Each of the first conductive layers has a length in the vertical direction that is shorter than a length in the vertical direction of each of the second conductive layers.
US08728912B2 Method for manufacturing SOI wafer
The present invention is directed to a method for manufacturing an SOI wafer, the method by which treatment that removes the outer periphery of a buried oxide film to obtain a structure in which a peripheral end of an SOI layer of an SOI wafer is located outside a peripheral end of the buried oxide film, and, after heat treatment is performed on the SOI wafer in a reducing atmosphere containing hydrogen or an atmosphere containing hydrogen chloride gas, an epitaxial layer is formed on a surface of the SOI layer. As a result, there is provided a method that can manufacture an SOI wafer having a desired SOI layer thickness by performing epitaxial growth without allowing a valley-shaped step to be generated in an SOI wafer with no silicon oxide film in a terrace portion, the SOI wafer fabricated by an ion implantation delamination method.
US08728906B2 Reverse tone STI formation
A method includes forming a hard mask over a substrate, patterning the hard mask to form a first plurality of trenches, and filling a dielectric material into the first plurality of trenches to form a plurality of dielectric regions. The hard mask is removed from between the plurality of dielectric regions, wherein a second plurality of trenches is left by the removed hard mask. An epitaxy step is performed to grow a semiconductor material in the second plurality of trenches.
US08728905B2 Stress-generating shallow trench isolation structure having dual composition
A shallow trench isolation structure containing a first shallow trench isolation portion comprising the first shallow trench material and a second shallow trench isolation portion comprising the second shallow trench material is provided. A first biaxial stress on at least one first active area and a second bidirectional stress on at least one second active area are manipulated separately to enhance charge carrier mobility in middle portions of the at least one first and second active areas by selection of the first and second shallow trench materials as well as adjusting the type of the shallow trench isolation material that each portion of the at least one first active area and the at least one second active area laterally abut.
US08728895B1 Double diffused metal oxide semiconductor device and manufacturing method thereof
The present invention discloses a double diffused metal oxide semiconductor (DMOS) device and a manufacturing method thereof. The DMOS device includes: an isolation structure for defining device regions; a gate with a ring-shaped structure; a drain located outside the ring; and a lightly doped drain, a source, and a body electrode located inside the ring. To increase the sub-threshold voltage at the corners of the gate, the corners are located completely on the isolation structure, or the lightly doped drain is apart from the corners by a predetermined distance.
US08728893B2 Method of fabricating a three-dimentional semiconductor memory device
A method of fabricating a semiconductor memory device includes alternately and repeatedly stacking sacrificial layers and insulating layers on a substrate, forming an active pattern penetrating the sacrificial layers and the insulating layers, continuously patterning the insulating layers and the sacrificial layers to form a trench, removing the sacrificial layers exposed in the trench to form recess regions exposing a sidewall of the active pattern, forming an information storage layer on the substrate, forming a gate conductive layer on the information storage layer, such that the gate conductive layer fills the recess regions and defines an empty region in the trench, the empty region being surrounded by the gate conductive layer, and performing an isotropic etch process with respect to the gate conductive layer to form gate electrodes in the recess regions, such that the gate electrodes are separated from each other.
US08728889B2 Contact structure and manufacturing method thereof
A semiconductor memory device includes conductive patterns vertically stacked on the substrate and having pad regions extended further at edge portions of the conductive patterns as the conductive patterns descend from an uppermost conductive pattern to a lowermost conductive pattern, a first contact plug disposed on a first pad region of the lowermost conductive pattern, a buffer conductive pattern disposed on a second pad region positioned above the first pad region, and a second contact plug formed on the buffer conductive pattern.
US08728883B2 Semiconductor device and method for manufacturing semiconductor device
A highly reliable semiconductor device is manufactured by giving stable electric characteristics to a transistor in which an oxide semiconductor film is used for a channel. An oxide semiconductor film which can have a first crystal structure by heat treatment and an oxide semiconductor film which can have a second crystal structure by heat treatment are formed so as to be stacked, and then heat treatment is performed; accordingly, crystal growth occurs with the use of an oxide semiconductor film having the second crystal structure as a seed, so that an oxide semiconductor film having the first crystal structure is formed. An oxide semiconductor film formed in this manner is used for an active layer of the transistor.
US08728882B2 Manufacturing method for thin film transistor array panel
A manufacturing method for a thin film transistor array panel includes: providing a gate line including a gate electrode, on a substrate; providing a gate insulating layer covering the gate line; providing a semiconductor material layer on the gate insulating layer; providing a data wire material layer on the semiconductor material layer; providing a first photosensitive film pattern on the data wire material layer; etching the data wire material layer by using the first photosensitive film pattern as a mask; providing a second photosensitive film pattern by etching back the first photosensitive film pattern; etching the semiconductor material layer by using the second photosensitive film pattern as a mask; and etching the data wire material layer by using the second photosensitive film pattern as a mask to form a source electrode and a drain electrode. The etching the semiconductor material layer uses a first non-sulfur fluorinated gas.
US08728881B2 Semiconductor device and method for manufacturing the same
Semiconductor devices and methods for manufacturing the semiconductor devices are disclosed. A semiconductor device includes a substrate, a fin formed above the substrate with a semiconductor layer formed between the substrate and the fin, and a gate stack crossing over the fin. The fin and the semiconductor layer may include different materials and have etching selectivity with respect to each other. A patterning of the fin can be stopped reliably on the semiconductor layer. Therefore, it is possible to better control the height of the fin and thus the channel width of the final device.
US08728879B2 Formation of a zinc passivation layer on titanium or titanium alloys used in semiconductor processing
Embodiments of the current invention describe methods of processing a semiconductor substrate that include applying a zincating solution to the semiconductor substrate to form a zinc passivation layer on the titanium-containing layer, the zincating solution comprising a zinc salt, FeCl3, and a pH adjuster.
US08728876B2 Method of manufacturing semiconductor device
The invention prevents a conductive fuse blown out by laser trimming from reconnecting by a plating electrode in a plating process and prevents a plating solution etc from entering a fuse blowout portion. On a semiconductor substrate of a multilayered wiring structure including a fuse blowout groove formed by blowing out a conductive fuse by laser trimming in a trimming element forming region, a second protection layer is formed so as to cover the trimming element forming region and then a plating electrode is formed on an draw-out pad electrode made of a topmost metal wiring. A third protection layer is then formed so as to cover the semiconductor substrate including the second protection layer and have an opening on the plating electrode.
US08728873B2 Methods for filling a contact hole in a chip package arrangement and chip package arrangements
In various embodiments, a method for filling a contact hole in a chip package arrangement is provided. The method may include introducing electrically conductive discrete particles into a contact hole of a chip package; and forming an electrical contact between the electrically conductive particles and a contact terminal of the front side and/or the back side of the chip.
US08728870B2 Thin film silicon wafer and method for manufacturing the same
Provided are a thin film silicon wafer having high gettering capability, a manufacturing method therefor, a multi-layered silicon wafer formed by laminating the thin film silicon wafers, and a manufacturing method therefor. The thin film silicon wafer is manufactured by: forming one or more gettering layers immediately below a device layer which is formed in a vicinity of a front surface of a semiconductor silicon wafer; fabricating a device in the device layer of the semiconductor silicon wafer; and after the device has been fabricated, removing part of the semiconductor silicon wafer from a rear surface thereof to immediately below the gettering layers so as to leave at least one of the gettering layers in place. As a result, the thin film silicon wafer is allowed to have gettering capability even after having been reduced in thickness to be in a thin film form.
US08728862B2 Thin film transistor, method of manufacturing the same and flat panel display device having the same
A thin film transistor, a method of manufacturing the thin film transistor, and a flat panel display device including the thin film transistor. The thin film transistor includes: a gate electrode formed on a substrate; a gate insulating film formed on the gate electrode; an activation layer formed on the gate insulating film; a passivation layer including a compound semiconductor oxide, formed on the activation layer; and source and drain electrodes that contact the activation layer.
US08728860B2 Method for manufacturing semiconductor device
Electrical characteristics of transistors using an oxide semiconductor are greatly varied in a substrate, between substrates, and between lots, and the electrical characteristics are changed due to heat, bias, light, or the like in some cases. In view of the above, a semiconductor device using an oxide semiconductor with high reliability and small variation in electrical characteristics is manufactured. In a method for manufacturing a semiconductor device, hydrogen in a film and at an interface between films is removed in a transistor using an oxide semiconductor. In order to remove hydrogen at the interface between the films, the substrate is transferred under a vacuum between film formations. Further, as for a substrate having a surface exposed to the air, hydrogen on the surface of the substrate may be removed by heat treatment or plasma treatment.
US08728857B1 Photovoltaic solar cell
A photovoltaic solar cell for generating electricity from sunlight is disclosed. The photovoltaic solar cell comprises a plurality of spaced-apart point contact junctions formed in a semiconductor body to receive the sunlight and generate the electricity therefrom, the plurality of spaced-apart point contact junctions having a first plurality of regions having a first doping type and a second plurality of regions having a second doping type. In addition, the photovoltaic solar cell comprises a first electrical contact electrically connected to each of the first plurality of regions and a second electrical contact electrically connected to each of the second plurality of regions, as well as a passivation layer covering major surfaces and sidewalls of the photovoltaic solar cell.
US08728856B2 Method of manufacturing upwardly tapering heaters for phase change memories
A substantially planar heater for a phase change memory may taper as it extends upwardly to contact a chalcogenide layer. As a result, the contact area between heater and chalcogenide is reduced. This reduced contact area can reduce power consumption in some embodiments.
US08728854B2 Semiconductor material, solar cell using the semiconductor material, and methods for producing the semiconductor material and the solar cell
A method for producing a semiconductor material, comprises a step of allowing impurity atoms, Ba atoms and Si atoms to react with each other, the impurity atoms being at least one atom selected from the group consisting of As atom, Sb atom, Bi atom and N atom; and a solar cell comprises the semiconductor material.
US08728852B2 Solid-state imaging device, production method thereof, and electronic device
A solid-state imaging device which includes a pixel section, a peripheral circuit section, a first isolation region formed with a STI structure on a semiconductor substrate in the peripheral circuit section, and a second isolation region formed with the STI structure on the semiconductor substrate in the pixel section. The portion of the second isolation region buried into the semiconductor substrate is shallower than the portion buried into the semiconductor substrate of the first isolation region, and the height of the upper face of the second isolation region is equal to that of the first isolation region. A method of producing the solid-state imaging device and an electronic device provided with the solid-state imaging devices are also disclosed.
US08728849B1 Laser cutting through two dissimilar materials separated by a metal foil
A method of laser cutting through dissimilar materials separated by a metal foil. A material stack includes a semiconductor layer or film, with a metal foil layer attached to the back surface. The metal foil layer is attached to an insulative support material layer. A laser parameter is selected and optimized for the material stack. A laser beam creates a kerf in the material stack down to the metal foil layer. The laser beam removes metal through the kerf primarily by gasification rather than melting. Kerf formation continues after optimization of the laser parameter for removal of material from the remaining layers. A debris field resulting from the laser cutting of the metal layer is reduced and/or a portion of the debris is removed in an assisted manner as the beam cuts. The materials are diced by cutting the kerf through all materials.
US08728848B2 Solution processing method for forming electrical contacts of organic devices
A method for forming, on an organic semiconductor layer, an electrical contact layer comprising a metal, is disclosed. In one aspect, the method includes providing a charge collecting barrier layer on the organic semiconductor layer, providing a liquid composition comprising a precursor for the metal on the charge collecting barrier layer, and performing a sintering process. The charge collecting barrier layer is substantially impermeable to the components of the liquid composition.
US08728844B1 Backside CMOS compatible bioFET with no plasma induced damage
The present disclosure provides a bio-field effect transistor (BioFET) device and methods of fabricating a BioFET and a BioFET device. The method includes forming a BioFET using one or more process steps compatible with or typical to a complementary metal-oxide-semiconductor (CMOS) process. The BioFET device includes a gate structure disposed on a first surface of a substrate and an interface layer formed on a second surface of the substrate. The substrate is thinned from the second surface to expose a channel region before forming the interface layer.
US08728843B2 Nitride semiconductor light emitting element and method for manufacturing same
A nitride semiconductor light emitting element has; a laminate of a first conduction type semiconductor layer, a light emitting layer and a second conduction type semiconductor layer of a different conduction type from that of the first conduction type semiconductor layer; and electrodes with a laminate structure formed on the first conduction type semiconductor layer, the electrodes include a conductive region of a first layer which has the conductive region and an insulated region.
US08728840B2 Solid state lighting devices with reduced crystal lattice dislocations and associated methods of manufacturing
Solid state lighting devices and associated methods of manufacturing are disclosed herein. In one embodiment, a solid state lighting device includes a substrate material having a substrate surface and a plurality of hemispherical grained silicon (“HSG”) structures on the substrate surface of the substrate material. The solid state lighting device also includes a semiconductor material on the substrate material, at least a portion of which is between the plurality of HSG structures.
US08728835B2 Light scattering by controlled porosity in optical ceramics for LEDs
The present invention relates to a light emitting device (100) comprising at least one light emitting diode (101) and at least one porous ceramic element (102), which ceramic element (102) is arranged to receive light from the light emitting diode(s) (101). The present invention also relates to methods for the manufacture of the light emitting device (100) and of the porous ceramic element (102).
US08728834B2 Semiconductor device and a method of manufacturing the same
A semiconductor device is manufactured by forming at least one epitaxial structure over a substrate. A portion of the substrate is cut and lifted to expose a partial surface of the epitaxial structure. A first electrode is then formed on the exposed partial surface to result in a vertical semiconductor device.
US08728829B2 Compositions for binding to assay substrata and methods of using
Compositions and methods for binding to assay substrata in a stable and protective manner, thereby enhancing assay performance, are provided. The compositions comprise lyotropic materials (for example, lyotropic liquid and/or liquid crystalline materials) and may contain macromolecular standards, markers or capture compounds. The compositions are capable of binding to assay substrata such as that of chips that are employed for MALDI and SELDI mass spectroscopy analyzes and plates that are used for ELISA type assays.
US08728828B2 Purification of immunoglobulins
The present invention relates to a separation matrix comprised of porous particles to which antibody-binding protein ligands have been immobilized, wherein the ligand density is in the range of 5.0-10 mg/ml; the gel phase distribution coefficient of the particles expressed as Kav for a dextran of size 110 kDa is above 0.65 and the median particle diameter is between 65-84 μm. The carbohydrate material is preferably highly cross-linked agarose.
US08728824B2 Mass spectrometric determination of fatty acids
The invention relates to the detection of fatty acids. In a particular aspect, the invention relates to methods for detecting very long chain fatty acids and branched chain fatty acids by mass spectrometry.
US08728823B2 Methods for detecting lung cancer and monitoring treatment response
A method is described for detecting lung cancer comprising detecting an elevated level of a CTAP III-related biomarker in a biological sample from a subject at risk for developing lung cancer. Further, a method is described for predicting risk of developing lung cancer in a subject comprising detecting an elevated level of a CTAP III-related biomarker in a biological sample from a subject. Additionally, a method of monitoring the success of lung cancer treatment is described comprising detecting levels of a CTAP III-related biomarker in a biological sample from a subject undergoing treatment for lung cancer for comparison with a previous level obtained from the subject. Multivariate analysis may be incorporated into these methods, evaluating such clinical, or demographic risk factors as age, sex, smoking history, smoking status, smoking family history, education level, COPD, socio-economic status, body mass index and lung function. Kits for conducting such methods are described.
US08728822B2 Method, apparatus, and recording medium for performance game
Disclosed is a performance game, and more particularly is a method, an apparatus, and a recording medium for a performance game, which can provide various presentation effects with a simple presentation operation of a user.
US08728819B2 Methods for culturing minimally-passaged fibroblasts and uses thereof
The present invention relates to novel methods of growing at least 100 million minimally-passaged fibroblasts from a small biopsy specimen. The invention includes methods wherein a small biopsy specimen is seeded directly into a large tissue culture flask, and passaged no more than three times.
US08728818B2 Defined cell culturing surfaces and methods of use
In one aspect, there is provided a cell culturing substrate including: a cell culture surface having a film attached thereto, wherein the film includes one or more plasma polymerized monomers; and a coating on the film-coated surface, the coating deposited from a coating solution comprising one or more extracellular matrix proteins and an aqueous solvent, where the total extracellular matrix protein concentration in the coating solution is about 1 ng/mL to about 1 mg/mL.
US08728815B2 Induction of differential stress resistance and uses thereof
This invention relates to methods of inducing differential stress resistance in a subject with cancer by starving the subject for a short term, administering a cell growth inhibitor to the subject, or reducing the caloric or glucose intake by the subject. The induced differential stress resistance results in improved resistance to cytotoxicity in normal cells, which, in turn, reduces cytotoxic side-effects due to chemotherapy, as well as improved effectiveness of chemotherapeutic agents.
US08728812B2 Compositions and methods for promoting the generation of PDX1+ pancreatic cells
Certain embodiments disclosed herein are directed to a method of producing pancreatic cells or pancreatic cell precursors by exposing human embryonic stem cells to an effective amount of at least one compound listed in Table I to differentiate the human embryonic stem cells into the pancreatic cells or the pancreatic cell precursors. Kits and pancreatic cell lines produced using the methods are also described.
US08728803B2 Thermophilic and thermoacidophilic metabolism genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods
Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering metabolism in a cell using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
US08728799B2 Apparatus and method for isolating histological sections produced with a microtome
An apparatus and a method for isolating histological sections produced with a microtome and a microtome are suggested. A previously and currently produced histological section are connected to form a section strip. In order to simplify isolating the previously and currently produced histological sections from each other a nozzle device is provided by means of which the histological sections when positioned on a blade holder are subjected to an air stream of adjusted direction and intensity so that the previously produced histological section of the section strip is separated from the currently produced histological section that is positioned on the blade holder and is removed from the blade holder.
US08728797B2 Yeast membrane protein expression system and its application in drug screening
The invention relates to an in vitro cell based expression system for overexpressing heterologous pump proteins associated with drug resistance into the membrane of the host cell for drug screening applications.
US08728796B2 Tiacumicin production
Methods, processes and materials for the production and recovery of Tiacumicins produced by culturing a microorganism belonging to the species Dactylosporangium aurantiacum subspecies hamdenensis having the ability to produce and accumulate one or more Tiacumicin in a nutrient medium comprising a carbon source, a nitrogen source, trace elements such as inorganic salts, and an adsorbent, wherein said nitrogen source comprises fish powder, and wherein said Tiacumicin is produced in a yield greater than about 50 mg/L broth.
US08728794B2 Strain conferring anti-disease properties to host and bacterial cell composition
The present invention provides a novel bacterial cell composition which comprises cells of Butyrivibrio fibrisolvens having the ability to produce butyric acid, a cultured material thereof or an extract thereof, and a method for inhibiting carcinogenesis, a method for immunostimulating, a method for preventing or treating a pathogen, a method for preventing or treating an inflammatory bowel disease and a method for preventing or treating an allergic disease, which use the same.
US08728792B2 Modified ethylenediamine-N, N′-disuccinate: ethylenediamine lyase
The present invention provides a modified ethylenediamine-N,N′-disuccinate:ethylenediamine lyase. The present invention also provides a protein that comprises the amino acid sequence represented by SEQ ID NO: 1; or a protein that comprises an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 1 by deletion, substitution, or addition of one or more amino acid residues, and has an ethylenediamine-N,N′-disuccinate:ethylenediamine lyase activity.
US08728790B2 Compositions and methods comprising protease variants
The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions.
US08728785B2 Additive for bioleaching that is substantially made up of the Licanantase lipoprotein, and bioleaching process to which this additive is added to increase the recovery of copper
The invention discloses an additive for bioleaching that makes it possible to increase the recovery of copper from sulfide ores. In which this additive is substantially made up of the Licanantase lipoprotein and a solution of sulfuric acid with a pH of 0.8 to 3. The Licanantase lipoprotein that has an amino acid sequence with at least 50% homology regarding the sequence defined in SEQ ID No. 1 or is the product of translation of a nucleotide sequence with at least 50% homology regarding the sequence defined in SEQ ID No. 2. It also protects the improved bioleaching process that includes adding the additive during the ore bioleaching process as defined in the present invention; and continuing with the habitual process, obtaining copper recoveries increased 5 to 20%.
US08728784B2 Method for fluid flow containment in an open liquid environment
A method is provided for fluid flow containment in an open liquid environment at least partially defined by a surface. The method includes the step of positioning a microfluidic device over the surface. The microfluidic device defines a chamber having a height. A flow of fluid is applied in the chamber. The pressure of the flow of fluid is monitored and the height of the chamber is determined from the measured pressure of the flow of fluid.
US08728782B2 Method of extracting butyric acid from a fermented liquid and chemically converting butyric acid into biofuel
Disclosed is a method of converting butyric acid contained in a fermentation broth into biofuel. This chemical conversion method includes separating biohydrogen from gases generated in the course of production of butyric acid through fermentation of carbohydrate, extracting butyric acid from the broth using an insoluble solvent, esterifying butyric acid thus producing butylbutyrate, and hydrogenolyzing all or part of butylbutyrate, thus obtaining butanol. Thereby, biobutanol can be efficiently and economically produced, and butylbutyrate, which has oxidation stability superior to that of conventional biodiesel (fatty acid methyl ester) and is thus regarded as novel biofuel, can be produced together.
US08728781B2 Endophytic yeast strains, methods for ethanol and xylitol production, methods for biological nitrogen fixation, and a genetic source for improvement of industrial strains
The present invention provides novel endophytic yeast strains capable of metabolizing both pentose and hexose sugars. Methods of producing ethanol and xylitol using the novel endophytic yeast are provided herein. Also provided are methods of fixing nitrogen and fertilizing a crop using the novel endophytic yeast strains provided herein.
US08728780B2 Process for producing hydroxycarboxylic acid
An object of the invention is to produce a microorganism which yields high amounts in a short time of a hydroxycarboxylic acid reduced in impurity content. This invention further provides a process for producing a hydroxycarboxylic acid, including glycolic acid, using the microorganism. This process enables a hydroxycarboxylic acid having high purity to be supplied at low cost.
US08728777B2 High performance metabolic bacteria
The present invention relates to novel stress-resistant bacteria and the uses thereof. More specifically, the invention relates to isolated stress-resistant bacteria having advantageous properties for the production of organic acids or alcohols in various culture conditions. The invention also relates to methods of producing organic acids or alcohols using said bacteria, particularly from biomass.
US08728775B2 Method for preparing 2-pyrrolidone using a microorganism containing glutamate decarboxylase
The present invention relates to a method for preparing 2-pyrrolidone using biomass, comprising: a step (a) of culturing a microorganism which contains glutamate decarboxylase as a whole-cell catalyst in a culture medium containing glutamic acid or glutamate so as to prepare 4-amino butyric acid; a step (b) of filtering the 4-amino butyric acid from the culture medium in order to obtain the 4-amino butyric acid; and a step (c) of converting the 4-amino butyric acid into 2-pyrrolidone. The present invention provides a series of processes for preparing 2-pyrrolidone from glutamic acid or glutamate using biomass. According to the present invention, 4-amino butyric acid is prepared using a microorganism as a whole cell, and preferably, 4-amino butyric acid which has not undergone a complicated refining process such as a crystallization process is directly used to prepare 2-pyrrolidone at a high yield rate in an economically advantageous manner. According to the present invention, 2-pyrrolidone may be mass-produced at a high yield rate and low production costs. The method of the present invention simplifies processes for preparing 2-pyrrolidone, and thus is suitable for mass production at an industrial scale.
US08728772B2 Method for producing an L-amino acid
An L-amino acid is produced by culturing a bacterium having an L-amino acid-producing ability in a medium containing a processed product of a microalga which promotes production and accumulation of the L-amino acid by the bacterium. The process product is produced by disrupting the culture of the microalga, and/or extracting the culture of the microalga, or fractionating the culture of the microalga or the disrupted culture. The processed product contains a mixture of organic substances produced by the microalga, a hydrolysate of the disrupted microalga culture, and/or an extract or fractionation product of the microalga culture. The processed product can also contain a saccarification product of starch or a hydrolysate of fats and oils. The bacterium is cultured to produce and accumulate the L-amino acid in culture, and the L-amino acid is collected from the culture.
US08728771B2 L-succinylaminoacylase and process for producing L-amino acid using it
The present invention provides a L-succinylacylase consisting of: (a) a protein coded by a gene consisting of a nucleic acid sequence shown in SEQ ID No: 1; (b) a protein consisting of an amino acid sequence shown in SEQ ID No: 2; (c) a protein coded by a polynucleotide which hybridizes under a stringent condition with a nucleic acid sequence which is complementary to the nucleic acid sequence shown in SEQ ID No: 1 and having an L-succinylaminoacylase activity; or (d) a protein which consists of an amino acid sequence where one or several amino acid(s) is/are substituted, deleted, inserted and/or added in the protein consisting of the amino acid sequence shown in SEQ ID No: 2 and has an L-succinylaminoacylase activity. This enzyme is able to produce a sterically bulky unnatural amino acid such as L-tert-leucine etc. which is useful as an intermediate for pharmaceuticals.
US08728764B2 Nucleic acid sample enrichment for sequencing applications
The present invention relates to the field of molecular biology, and more specifically to methods for reducing the complexity of a nucleic acid sample.
US08728759B2 Reverse cumate repressor mutant
Recently, the development of inducible expression systems has involved exploitation of the p-cym operon from Pseudomonas putida. Disclosed herein are novel expression systems and components thereof, which involve the development of CymR variants with reverse DNA binding activity, such that they exhibit increased affinity for DNA in a presence rather than an absence of an effector molecule such as cumene or an equivalent thereof. Also disclosed are the CymR variants, fusion proteins incorporating such variants, and their use in the control and expression of polynucleotides.
US08728757B2 Methods of modulating cold sensory perception via a cold- and menthol-sensitive receptor (CMR1)
The present invention relates to regulation of cold sensation and pain. More particularly, the present invention is directed to nucleic acids encoding a member of the transient regulatory protein family, CMR1, which is involved in modulation of the perception of cold sensations and pain. The invention further relates to methods for identifying and using agents that modulate cold responses and pain responses stimulated by cold via modulation of CMR1 and CMR1-related signal transduction.
US08728755B2 Measurement of sequestered carbon
Disclosed herein are methods and systems for determining an amount of carbon dioxide that can be sequestered from the atmosphere by a portion of an ocean. The methods or systems involve the following steps (a) determining which chemical element or elements would, when added to a photic zone of the portion, cause growth of a phytoplankton population in the portion; (b) determining a quantity of the chemical element or elements to be added to the photic zone whereby substantially all of the element or substantially all of at least one of the elements added would be consumed by the additional phytoplankton grown: and (c) calculating the amount of carbon dioxide that can be sequestered from the atmosphere based on the determined quantity of the chemical element or elements that would be added to the portion.
US08728753B2 Methods for measuring the level of insulin-like growth factor 1 receptor (IGF1R) protein using SRM/MRM assay
Peptides from the Insulin-Like Growth Factor 1 Receptor (IGF-1R) protein are provided that are particularly advantageous for quantifying the IGF-1 R protein directly in biological samples, such as samples fixed in formalin. The ionization characteristics of the peptides also are disclosed. The peptides may be used in Selected Reaction Monitoring (SRM) mass spectrometry methods, also referred to Multiple Reaction Monitoring (MRM) mass spectrometry methods. The samples are chemically preserved and fixed, such as tissues and cells treated with formaldehyde containing agents/fixatives including formalin-fixed tissue/cells, formalin fixed/paraffin embedded (FFPE) tissue/cells, FFPE tissue blocks and cells from those blocks, and tissue culture cells that have been formalin fixed and or paraffin embedded. A protein sample may be prepared from the biological sample and the IGF-IR protein is quantitated by the method of SRM/MRM mass spectrometry by quantitating one or more of the described peptides. These peptides can be quantitated in either modified or unmodified form. An example of a modified form of an IGF-1 R peptide is phosphorylation of a tyrosine, threonine, serine, and/or other amino acid residues within the peptide sequence.
US08728752B2 Method for isolating Trichinella or other parasites from organic tissue
The present invention relates to a method for the detection of essentially intact encapsulated or non-encapsulated parasites in meat, comprising the maceration of the meat with an alkaline digestion solution which contains a digestive enzyme that is active in an alkaline environment. Further, uses of a serine endopeptidase in a method for the detection of essentially intact encapsulated or non-encapsulated parasites in meat are described. The present invention also describes serine endopeptidases for use in a diagnostic method for the detection of essentially intact encapsulated or non-encapsulated parasites in meat. Finally, a kit is disclosed which comprises the enzymes and alkaline digestion solutions of the present invention.
US08728751B2 System and method for diagnosing lymphoma in cats
The invention provides a method and a system for diagnosing lymphoma in cats. The system allows a care giver to measure the enzymatic activity of thymidine kinase in a blood sample. The invention teaches that when the enzymatic activity of thymidine kinase in the blood stream of a cat is above 15.5 Units per liter, the cat has a high probability of having lymphoma. The invention allows for initial diagnosis, follow up after treatment for lymphoma and/or monitoring for example in breeds that prone to have lymphoma.
US08728745B2 Method for prediction of the progression risk of tumors
The present invention concerns a method for predicting the potential for aggressive growth and/or the risk to progress to high grade cancer for tumors in cell based detection procedures. In one aspect the invention concerns the detection of overexpression of cyclin-dependent kinase inhibitor gene products as a tool for predicting the progression risk and/or potential for aggressive growth of tumors. In a second aspect the invention concerns predicting the progression risk and/or potential for aggressive growth in tumors on the basis of the simultaneous co-detection of the presence of overexpression of cyclin-dependent kinase inhibitor gene products together with the expression of markers for active cell proliferation. Further the invention concerns preparations of probes for diagnosis namely for predicting the progression risk and/or the potential for aggressive growth of tumors.
US08728744B2 Salivary protein biomarkers for human oral cancer
The present invention relates to the identification of novel oral cancer and periodontal disease biomarkers. Further, the present invention provides novel methods of diagnosing and for providing a prognosis for oral cancer and periodontal disease. The present invention additionally provides novel methods of distinguishing between oral cancer and periodontal disease. Finally, kits are provided that find use in the practice of the methods of the invention.
US08728742B2 Methods predicting risk of an adverse clinical outcome
Provided are methods for evaluating the risk of an adverse clinical outcome in a subject, deciding whether to discharge or continue treating a subject (e.g., on an inpatient basis), or to initiate or terminate treatment, selecting a subject for participation 5 in a clinical study, and selecting a therapeutic treatment for a subject that include determining a level of ST2 and a level of galectin-3 in a biological sample from the subject. Kits are also provided that contain an antibody that specifically binds to ST2, an antibody that specifically binds to galectin-3, and instructions for using the in the methods described.
US08728741B2 Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
The present application describes a monoclonal antibody selected from the group consisting of monoclonal antibody DS6, monoclonal antibodies that specifically bind to the antigen or epitope bound by monoclonal antibody DS6, and fragments of the foregoing that specifically bind to the antigen or epitope bound by monoclonal antibody DS6. Methods of use of such antibodies and the isolated antigen bound by such antibodies are also described.
US08728736B2 Methods and compositions for multiplex PCR
The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex PCR of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences. In one aspect, the invention relates to target-specific primers useful for the selective amplification of one or more target sequences associated with cancer or inherited disease. In some aspects, amplified target sequences obtained using the disclosed methods, kits, systems and apparatuses can be used in various downstream processes including nucleic acid sequencing and used to detect the presence of genetic variants.
US08728732B2 Global DNA hypomethylation and biomarkers for clinical indications in cancer
The present invention provides methods of determination of a global DNA methylation index (GDMI) in a sample from a subject, using a variety of methods which can detect global, genome-wide, and gene-specific DNA methylation to create methylation portraits that can be used for early detection, diagnosis, and clinical management in the personalized medicine space. Further, the invention provides methods of diagnosis of cancer, including gastric cancer and hepatocellular cancer in a subject, by comparing the GDMI in a sample obtained from a subject to the methylation index of standard controls. These methods allow diagnosis of gastric carcinoma and liver cancer in patients who may be asymptomatic or have inconclusive pathology, and allowing earlier treatment of the subject.
US08728730B2 Methods for treating, diagnosing, and monitoring rheumatoid arthritis
Methods of identifying, diagnosing, and prognosing rheumatoid arthritis are provided, as well as methods of treating rheumatoid arthritis. Also provided are methods for identifying effective rheumatoid arthritis therapeutic agents and predicting responsiveness to rheumatoid arthritis therapeutic agents.
US08728725B2 Chemically modified ligase cofactors, donors and acceptors
Provided herein are methods for ligation of polynucleotides containing modified ligation components, particularly modified ligase cofactors, modified acceptors and modified donors. The methods readily applied to ligation-based assays for detection of a nucleic acid sequence where the use of the modified cofactor improves discrimination between matched and mismatched templates. Furthermore, the use of the modified ligation components reduces or eliminates the ligation in the absence of nucleic acid template.
US08728721B2 Methods of processing substrates
A method of processing a substrate includes forming first photoresist on a substrate. A portion of the first photoresist is selectively exposed to actinic energy and then the first photoresist is negative tone developed to remove an unexposed portion of the first photoresist. Second photoresist is formed on the substrate over the developed first photoresist. A portion of the second photoresist is selectively exposed to actinic energy and then the second photoresist is negative tone developed to remove an unexposed portion of the second photoresist and form a pattern on the substrate which comprises the developed first photoresist and the developed second photoresist. Other implementations are disclosed.
US08728719B2 Diffractive laser beam homogenizer including a photo-active material and method of fabricating the same
A method of manufacturing a plurality of diffractive optical elements includes providing a partially transmissive slide, providing a first piece of PTR glass, and directing first UV radiation through the partially transmissive slide to impinge on the first piece of PTR glass. The method also includes exposing predetermined portions of the first piece of PTR glass to the first UV radiation and thermally treating the exposed first piece of PTR glass. The method further includes providing a second piece of PTR glass and directing second UV radiation through the thermally treated first piece of PTR glass to impinge on the second piece of PTR glass. The method additionally includes exposing predetermined portions of the second piece of PTR glass to the second UV radiation, thermally treating the exposed second piece of PTR glass, and repeating providing and processing of the second piece of PTR glass using additional pieces of PTR glass.
US08728718B2 Method for manufacturing liquid ejection head
There is provided a method for manufacturing a liquid ejection head having a substrate and a channel-forming member having an ejection port from which a liquid is ejected, the method including forming a negative photosensitive resin layer on or above the substrate; forming a lens layer on the negative photosensitive resin layer, the lens layer having a lens; exposing the negative photosensitive resin layer through the lens to form an ejection port in the negative photosensitive resin layer; and removing the lens layer.
US08728715B2 Non-photosensitive siloxane coating for processing hydrophobic photoimageable nozzle plate
A method of forming a patterned photoresist layer having a hydrophobic surface is provided. The method includes forming a photoresist layer on a substrate and image patterning. The photoresist layer may comprise a polymeric material. The imaged photoresist layer may then undergo a two-stage post-exposure bake. A surface treatment may be performed on the photoresist layer in between the two-stage post-exposure bake. The surface treatment may include applying a siloxane solution on a partially post-exposure baked photoresist layer. The post-exposure baked photoresist layer may then be developed to form the patterned photoresist layer. The method may be used to form a hydrophobic photoimageable nozzle plate of a micro-fluid ejection head having improved mechanical properties and stable hydrophobic properties.
US08728709B2 Lithographic printing plate precursor and plate making method thereof
A lithographic printing plate precursor includes a support and an image-recording layer containing a star polymer, a radical polymerizable compound and a radical polymerization initiator, the star polymer is a star polymer in which a polymer chain is branched from a central skeleton via a sulfide bond and the polymer chain contains an acid group and a crosslinkable group in a side chain of the polymer chain.
US08728707B2 Resist composition and method for producing resist pattern
A resist composition having a resin having a structural unit represented by the formula (I), a resin being insoluble or poorly soluble in alkali aqueous solution, but becoming soluble in an alkali aqueous solution by the action of an acid and not including the structural unit represented by the formula (I), an acid generator, and a compound represented by the formula (II), wherein R1, A1, A13, A14, X12, R23 and ring W21 are defined in the specification.
US08728705B2 Negative photosensitive material, photosensitive board employing the negative photosensitive material, and negative pattern forming method
A negative photosensitive material is provided which has a lower linear expansion coefficient and a lower hygroscopic expansion coefficient and is excellent in gradational patternability and PI etchability in patterning. The negative photosensitive material comprises: (A) a polyimide precursor having a structural unit represented by the following general formula (1) and a structural unit represented by the following general formula (2), the structural unit represented by the general formula (2) being present in the polyimide precursor in a proportion of less than 30 mol % based on the overall amount of the polyimide precursor; and (B) at least one of a pyridine derivative represented by the following general formula (3) and a pyridine derivative represented by the following general formula (4): wherein R1, R2, R3, R4 and R5, which may be the same or different, are each a C1 to C4 alkyl group, and Ar is an aryl group having a nitro group at its ortho position, wherein R1, R2, R4 and R5, which may be the same or different, are each a C1 to C4 alkyl group, and Ar is an aryl group having a nitro group at its ortho position.
US08728702B2 Toner and toner binder
A polyester resin toner binder which gives a toner with good anti-blocking property at high temperature and high humidity and good low-temperature fixing ability. The present invention is directed to a toner binder for developing electrostatic charge images, which binder comprises a condensation-polymerization polyester resin, the polyester resin being a product formed in the presence of a catalyst (a) represented by the following general formula (I): Ti(—X)m(—OR)n  (I) wherein R, X, m and n are as defined herein.
US08728701B2 Production process of toner for electrostatic image development
The production process is a production process of a toner for electrostatic image development, which is composed of toner particles containing at least a binder resin. The process has an aggregating and fusion-bonding step of adding a aggregating agent containing polysilicato-iron into an aqueous medium in which fine binder resin particles formed of the binder resin have been dispersed, thereby aggregating the fine binder resin particles, and an aggregation stopper-adding step of adding an aggregation stopper composed of a polyvalent organic acid or a salt thereof. In the production process of the toner for electrostatic image development, the polyvalent organic acid or the salt thereof is preferably an amino acid or a salt thereof.
US08728700B2 Reactor, toner production method, and toner
A reactor, which heats a slurry raw material including a solid component, including a reaction tube, wherein the slurry raw material is continuously fed from an end of the reaction tube relative to the central axial direction of the reaction tube so as to be flown toward another end of the reaction tube to be heated; and plural perforated plates arranged in the reaction tube so as to separate the inside of the reaction tube into plural compartments. The reactor satisfies the relations (½)·D′≦D
US08728694B2 Electrostatic latent image-developing toner and method for forming image
An image is formed with an electrostatic latent image-developing toner that includes toner base particles and titanium oxide serving as an external additive. The toner base particles containing a binder resin, a colorant, and a charge control agent. The titanium oxide is attached to surfaces of the toner base particles and containing titanium oxide A and titanium oxide B. Each of the titanium oxide A and the titanium oxide B has a predetermined particle diameter and a predetermined volume resistivity. The liberation rate of each of the titanium oxide A and the titanium oxide B in the toner is within a predetermined range.
US08728693B2 Toner for developing electrostatic image, method of producing toner, cartridge, image forming method, and image forming apparatus
A toner for developing an electrostatic image, includes: colored particles containing a colorant and a binder resin, and two or more kinds of inorganic particles that are externally added to a surface of the colored particles, in which the two or more kinds of inorganic particles contain titanium-containing particles and silica-containing particles, an exposure ratio of the surface of the colored particles is about 25% or less, and a ratio of the titanium-containing particles that are in contact with the colored particles is about 15% by number or less.
US08728689B2 Full-color image-forming method
Provided are a toner containing at least a binder resin and a colorant, the toner having a specific hue angle and an absorbance at a specific wavelength in reflectance spectrophotometry, and a full-color image-forming method involving the use of the toner, the method including the steps of: forming an electrostatic image on a charged electrostatic image bearing member; developing the formed electrostatic image with the toner to form a toner image; transferring the formed toner image onto a transfer material; and fixing the transferred toner image to the transfer material to form a fixed image.
US08728688B2 Colored curable composition, color filter and method of producing the same, and dipyrromethene metal complex compound and tautomer thereof
A colored curable composition is provided which has good developability, has excellent color purity, can be formed into a thin film, and has a high absorption coefficient. The colored curable composition includes at least one of specific dipyrromethene metal complex compounds and tautomers thereof. Also, a colored curable composition suitable for forming a color filter which is used in a liquid crystal display device or a solid-state imaging device, and a color filter using the colored curable composition and a method of producing the same are provided.
US08728687B2 Resin, pigment dispersion, colored curable composition, color filter produced using the same, and method for producing the same
A resin including (i) a main chain portion containing a nitrogen atom, (ii) a group X that has a functional group having a pKa of 14 or less and is bonded to a nitrogen atom present in the main chain portion, and (iii) an oligomer chain or polymer chain Y having a number average molecular weight of from 500 to 1,000,000 in a side chain.
US08728683B2 Fuel cell
A cell unit of a fuel cell includes a first separator, a first membrane electrode assembly, a second separator, a second membrane electrode assembly, and a third separator. Resin connecting sections are provided in the outer circumferential ends of the first separator, the second separator, and the third separator. A coupling pin is molded integrally with the resin connecting section of the first separator. A first hole and a second hole are formed on both sides of the coupling pin for selectively inserting a rebuilt pin into either of the first and second holes. A hole for inserting the coupling pin is formed at the center, and the first hole and the second hole are formed on both sides of the hole, in each of the resin connecting sections of the second and third separators.
US08728682B2 Fuel cell having a fastening structure including a specified configuration of elastic members
A fuel cell of the present invention includes: four fastening bolts which extend in a stack direction of a stack structure so as to penetrate through openings of end plates and nuts which are disposed at both ends of the fastening bolts and can adjust fastening forces applied by the fastening bolts to the stack structure sandwiched between the end plates. Each fastening bolt is disposed in the vicinity of an intermediate point of each side of the end plate. In an electrode facing region of the end plate, one or more springs are disposed on a first straight line passing through two fastening bolts one or more springs are disposed on a second straight line passing through two fastening bolts one or more springs are disposed on a third straight line passing through two fastening bolts and one or more springs are disposed on a fourth straight line passing through two fastening bolts.
US08728673B2 Fuel cell system
A casing of a fuel cell system is divided into a fluid supply section, a module section, and an electrical equipment section. A detector, a fuel gas supply apparatus, an oxygen-containing gas supply apparatus, and a water supply apparatus are provided in the fluid supply section. A fuel cell module and a combustor are provided in the module section. A power converter and a control device are provided in the electrical equipment section. The module section is interposed between the fluid supply section and the electrical equipment section.
US08728670B2 Nonaqueous-electrolyte battery containing a negative electrode with a coating film formed by an isocyanate-containing compound in the nonaqueous electrolyte
The invention provides a nonaqueous-electrolyte battery which has a positive electrode 3 including a positive active material, a negative electrode 4 including a negative active material having a lithium insertion/release potential higher than 1.0 V (vs. Li/Li+), and a nonaqueous electrolyte, wherein an organic compound having one or more isocyanato groups has been added to the nonaqueous electrolyte.
US08728669B2 Nonaqueous electrolyte battery and battery pack
A nonaqueous electrolyte battery includes a positive electrode, a negative electrode and a nonaqueous electrolyte. The positive electrode contains active material particles and a coating material. The active material particles are represented by any one of the following formulae (1) to (3): LixM1yO2  (1) LizM22wO4  (2) LisM3tPO4  (3) and have an average particle diameter of 0.1 to 10 μm. The coating material comprises at least particles having an average particle diameter of 60 nm or less or layers having an average thickness of 60 nm or less. The particles or the layers contain at least one element selected from the group consisting of Mg, Ti, Zr, Ba, B and C.
US08728663B2 Positive electrode for lithium-ion secondary battery and lithium-ion secondary battery comprising that positive electrode
To provide a sulfur-system positive electrode for lithium-ion battery, sulfur-system positive electrode which is good in the cyclability and the other characteristics, and a lithium-ion secondary battery including that positive electrode. In a positive electrode for lithium-ion secondary battery, the positive electrode having: a current collector; and an electrode layer that is formed on a surface of the current collector, and which includes a binder resin, an active material and a conductive additive, the positive electrode is characterized in that the active material includes a sulfur-modified polyacrylonitrile that is produced by heating a raw-material powder including a sulfur powder and a polyacrylonitrile powder in an enclosed nonoxidizing atmosphere; and the binder resin includes a polyimide resin and/or a polyamide-imide resin.
US08728659B2 Alkaline cell with additive for improved discharge performance
The present disclosure generally relates to an alkaline electrochemical cell comprising an additive for improved discharge performance. The additive is a finely dispersed superabsorbent material comprising particles having a substantially uniform shape and a small particle size relative to typical materials used in alkaline cells. The superabsorbent material results in enhanced discharge performance of the alkaline cell by increasing access of zinc to the electrolyte.
US08728654B2 Electrode structure and battery device manufacturing method
An electrode is provided with a metal terminal extending from a battery module main body, a bolt which has an expanded section configuring a retaining section at a rear end portion and penetrates the metal terminal upward, and an insulating body which insulates the metal terminal and the battery module case one from the other. The insulating body is provided with a drop preventing section which abuts at least a lower surface of the expanded section of the bolt and prevents the bolt from dropping from the metal terminal.
US08728652B2 Cylindrical alkaline battery having specific electrode packing densities and electrode thickness
Provided is a cylindrical alkaline battery in which the packing density Dc of the manganese dioxide in the positive electrode is 2.8 to 3.0 g/cm3 and the packing density Da of zinc or a zinc alloy in the negative electrode is 2.0 to 2.3 g/cm3. The packing density Dc of the manganese dioxide, the packing density Da of the zinc or zinc alloy, the thickness Tc of the positive electrode in a radial direction, and the thickness Ta of the negative electrode in a radial direction satisfy one of the following relational formulas (1) to (3): −1.975×(Tc/Ta)+2.745
US08728650B2 Apparatus and method for enhancing impregnation with electrolyte in secondary battery
An apparatus for enhancing impregnation of the electrolyte in a secondary battery includes a tray in which at least one battery cell is received, and an oscillation and rotation unit capable of oscillating and rotating the tray simultaneously.
US08728644B2 Rechargeable battery
A rechargeable battery includes an electrode assembly having a first electrode plate, a separator and a second electrode plate, a first collector plate electrically connected to the first electrode plate, a second collector plate electrically connected to the second electrode plate, a case accommodating the electrode assembly, the first collector plate and the second collector plate, a first electrode terminal electrically connected to the first collector plate, a second electrode terminal electrically connected to the second collector plate, a first plate connected to the first collector plate and the first electrode terminal and sealing the case, a second plate connected to the second collector plate and the second electrode terminal and including a short-circuit plate, and an insulation plate interposed between the first plate and the second plate.
US08728643B2 Fuse unit for rechargeable battery with supporting member
A rechargeable battery including: an electrode assembly; a case having an opening to receive the electrode assembly; a cap plate covering the opening of the case; a terminal arranged at the cap plate and electrically connected to the electrode assembly; a current collecting member coupled to the electrode assembly and the terminal and including a fuse unit; and a supporting member coupled to the current collecting member and supporting the fuse unit.
US08728640B2 Battery pack and method of fabricating the same
A battery pack and a method of fabricating the same. The battery pack includes a bare cell including an electrode terminal, a protection circuit board electrically connected to the bare cell, the protection circuit board including a plurality of metal tabs arranged at opposite ends thereof, and a case surrounding the protection circuit board, the case being perforated by a plurality of first apertures arranged at locations that correspond to ones of the plurality of metal tabs. The method includes arranging a bare cell having a cap plate and an electrode terminal passing through a terminal aperture in the cap plate, electrically connecting a protection circuit board to the bare cell, the protection circuit board having metal tabs arranged at both ends thereof and arranging a case to surround the protection circuit board, the case being perforated by a plurality of first apertures that are arranged at locations that correspond to ones of the metal tabs.
US08728638B2 Magnetic disk substrate, method for manufacturing the same, and magnetic disk
Provided are a magnetic disk substrate that can be adapted to a reduction in flying height of a head in an HDD and to an increase in rotational speed therein, and a method of manufacturing such a substrate.In an annular glass substrate for a magnetic recording medium, a main surface (12) of the glass substrate is uniformly inclined from an inner peripheral end (13) to an outer peripheral end (14) and has an isotropic shape with respect to an axis passing through the center of the glass substrate. That is, it is rotationally symmetric with respect to an arbitrary angle rotation about the axis passing through the center of the glass substrate.
US08728636B2 Insulating glass unit with crack-resistant low-emissivity suspended film
A low-e insulating glass unit has a suspended, coated IR reflecting polymer sheet under tension, e.g. from heat shrinkage. The polymer sheet is coated with a multilayer stack of dielectric and metallic layers, including at least one silver layer deposited upon a zinc oxide seed layer that is at most 15 nm thickness. The use of zinc oxide ensures good seeding for high quality silver layer growth, thereby providing low emissivity. The thinness of the zinc oxide ensures that it resists cracking when the polymer sheet is tensioned.
US08728628B2 Passivant for hot-dip Al-Zn-coated sheet and preparation method and use thereof
The present invention provides a passivant for hot-dip Al—Zn-coated sheet of which the raw materials include: 2˜6 parts by weight of water soluble molybdate, 4˜12 parts by weight of water soluble manganese salt, 50˜100 parts by weight of basic silica sol and 50˜100 parts by weight of water soluble organic resin. The present invention also provides a method to prepare the passivant for hot-dip Al—Zn-coated sheet including the following steps: adding and dissolving water soluble molybdate and water soluble manganese salt into deionized water; adding basic silica sol into the solution and mixing well; adding water soluble organic resin into the solution and mixing well; regulating the pH value of the solution to 5˜8 by using phosphoric acid. The present invention also provides a hot-dip Al—Zn-coated sheet treated with the present passivant and a method to passivate hot-dip Al—Zn-coated sheet.
US08728622B2 Single-crystal substrate, group-III nitride crystal obtained using the same, and process for producing group-III nitride crystal
Provided is a base substrate with which a Group-III nitride crystal having a large area and a large thickness can be grown while inhibiting crack generation. A single-crystal substrate for use in growing a Group-III nitride crystal thereon, which satisfies the following expression (1), wherein Z1 (μm) is an amount of warpage of physical shape in a growth surface of the single-crystal substrate and Z2 (μm) is an amount of warpage calculated from a radius of curvature of crystallographic-plane shape in a growth surface of the single-crystal substrate: −40
US08728619B2 Highly functional polyethylene fiber excellent in forming processability
The present invention provides a highly functional polyethylene fiber excellent in the cut resistance, has a high dimensional stability at about room temperature at which products are used, has a high shrinkage rate and stress, and excellent in forming processability when processed at a low temperature much less than a melting point of a polyethylene. And the present invention provides a highly functional polyethylene fiber excellent in processability at a low temperature, wherein an intrinsic viscosity [η] is higher than or equal to 0.8 dL/g, and is not higher than 4.9 dL/g, ethylene is substantially contained as a repeating unit, and a thermal stress at 40° C. is lower than or equal to 0.05 cN/dtex, and a thermal stress at 70° C. is higher than or equal to 0.05 cN/dtex, and is not higher than 0.25 cN/dtex. Further the present invention provides strings, ropes, woven/knitted textiles, and gloves thereof.
US08728618B2 Coating composition for metal thin film and photoluminescent coating film formed from same
A coating composition for a metal thin film for coating a vapor-deposited film or sputtered film provided on the surface of a base material, comprising: a coating film forming component containing 50% by weight or more of urethane(meth)acrylate that is a reaction product of hydrogenated xylene diisocyanate and/or hydrogenated diphenylmethane diisocyanate, polyol, and (meth)acrylate having a hydroxyl group.
US08728614B2 Backside protective film for solar cell, method for producing same, and solar cell module
Disclosed is a backside protective film (1) for a solar cell, which sequentially has a first resin layer (11), a second resin layer (12) and a third resin layer (13). Both the first resin layer and second resin layer include a rubber containing reinforced aromatic vinyl-based resin having a maximum glass transition temperature of 90-120° C. and have a thickness of 10-300 μm. The first resin layer includes an infrared transmissible coloring agent, while the second resin layer includes a white-based coloring agent. The third resin layer includes a saturated polyester resin and has a thickness of 10-300 μm. The third resin layer has a dimension change ratio between before and after the film is left to stand still at a temperature of 135° C. for 30 minutes of ±0.5% or less.
US08728612B2 Ink jet recording method
With a white image where the dryness factor is 40% to 80%, since drying has appropriately progressed, it becomes difficult for the white image and color ink to mix, and in addition, it is possible to suppress wetting and spreading of the color ink when a color image is recorded using an ink jet method with color ink which contains a colorant. Accordingly, it is possible to obtain an ink jet recording method where deterioration in image quality is suppressed.
US08728610B2 Compound mold and structured surface articles containing geometric structures with compound faces and method of making same
A structured surface articles such as molds or sheeting are formed on a compound substrate including a machined substrate and a replicated substrate. In one embodiment, the structured surface is a cube corner element on a compound substrate. In another embodiment, the structured surface is a geometric structure that has a plurality of faces, where one face is located on the machined substrate and another face is located on the replicated substrate. In yet another embodiment, at least some of the faces include a compound face with a portion formed on the machined substrate and a portion formed on the replicated substrate. The method of making a structured surface article including a geometric structure having a plurality of faces includes forming an array of geometric structures in a first surface of a machined substrate; passivating selected locations of the first surface of the machined substrate; forming a replicated substrate of the machined substrate to form a compound substrate; forming an array of second geometric structures on a second surface opposite the first surface on the machined substrate; and removing selected portions from the second surface of the machined substrate.
US08728606B2 Thermoplastic material
A circuit package for housing semiconductor or other integrated circuit devices (“die”) includes a high-copper flange, one or more high-copper leads and a liquid crystal polymer frame molded to the flange and the leads. The flange includes a dovetail-shaped groove or other frame retention feature that mechanically interlocks with the molded frame. During molding, a portion of the frame forms a key that freezes in or around the frame retention feature. The leads include one or more lead retention features to mechanically interlock with the frame. During molding, a portion of the frame freezes in or adjacent these lead retention features. The frame includes compounds to prevent moisture infiltration and match its coefficient of thermal expansion (CTE) to the CTE of the leads and flange. The is frame is formulated to withstand die-attach temperatures. A lid is ultrasonically welded to the frame after a die is attached to the flange.
US08728603B2 Floor panel
A floor panel in the form of a multilayer, rectangular laminate with a soft core (10) of plastic, a décor film (12) on the upper side of the core (10), a transparent finishing layer (14) and a transparent lacquer layer (16) applied on the finishing layer (16), as well as a back-pull layer (18) on the back of the core (10), with a lockable tongue and groove connection at least at two mutually opposite edges of the panel (20, 22).
US08728597B2 System and method for sealing an opening in a wall in which at least one transport device such as a cable, conduit or tube has been fed through
A system comprising first and second fire-resistant parts for at least temporary fire-resistant sealing of an opening in a wall in which at least one transport device, such as a cable, conduit or tube, has been fed through or will be fed through. The first and second parts are each at least partly placeable in the opening. The first parts are designed to at least partly envelop the transport device and the second parts are designed to be placed between the first parts and/or between the first parts and an inner wall of the opening for the purpose of at least virtually completely sealing the opening. The first parts are substantially manufactured from a fire-resistant rubber. The second parts are manufactured from a fire-resistant material based on an elastomeric foam with a substantially closed cell structure. The foam includes at least one crust-forming, fire-retardant material.
US08728594B2 Heat-shrinkable white polyester film, process for producing heat-shrinkable white polyester film, label, and package
A heat-shrinkable white polyester film is provided which has extremely satisfactory cuttability along a perforation and has light-shielding properties. Also provided are: a label; and a process for producing the film with high productivity. The heat-shrinkable white polyester film comprises a polyester resin constituted of ethylene terephthalate as a main constituent component and containing at least 13 mol % one or more monomer ingredients capable of serving as an amorphous component among all components of the polyester resin. This film has specific heat shrinkability, specific light-shielding properties, and specific mechanical properties. The process is excellent in the productivity of the film. The label is obtained from the heat-shrinkable white polyester film.
US08728593B2 Polyvinyl alcohol films with improved resistance to oxidizing chemicals
A water-soluble film which comprises a saccharide component and a vinyl alcohol resin component, where the vinyl alcohol resin may include functional comonomer units such as sulfonic acid functional groups or salts thereof. Preferred are polyvinyl alcohol/2-methylacrylamido-2 methyl propane sulfonic acid resins (PVOH/AMPS) which may be purchased commercially with relatively higher or relatively lower characteristic viscosity. The films exhibit superior resistance to aggressive oxidizing chemicals and remain soluble in water after prolonged exposure thereto. The films are particularly useful for unit-dose packaging of chlorine-containing pool chemicals, such as trichloroisocyanuric acid.
US08728590B2 Liquid crystal composition and liquid crystal display device
The liquid crystal composition having a negative dielectric anisotropy contains two ring compound having a large optical anisotropy and a negatively large dielectric anisotropy as the first component, three ring compound having a large maximum temperature and a large dielectric anisotropy as the second component, three ring compound having a large optical anisotropy and a large dielectric anisotropy as the third component, and two ring compound having a small viscosity as the fourth component. The liquid crystal display device contains the compositions.
US08728589B2 Laser decal transfer of electronic materials
A laser decal transfer is used to generate thin film features by directing laser pulses of very low energy at the back of a target substrate illuminating an area of a thin layer of a high viscosity rheological fluid coating the front surface of the target. The illuminated area is shaped and defined by an aperture centered about the laser beam. The decal transfer process allows for the release and transfer from the target substrate to the receiving substrate a uniform and continuous layer identical in shape and size of the laser irradiated area. The released layer is transferred across the gap with almost no changes to its initial size and shape. The resulting patterns transferred onto the receiving substrate are highly uniform in thickness and morphology, have sharp edge features and exhibit high adhesion, independent of the surface energy, wetting or phobicity of the receiving substrate.
US08728582B2 Primers and a method of coating in which they are used
Disclosed is a primer having from 50 to 90 mass % of (A) a chlorinated polyolefin resin having a chlorine content of from 5 to 50 mass % and a weight average molecular weight of from 1,000 to 100,000, from 45 to 5 mass % of (B) a blocked polyisocyanate compound, from 45 to 5 mass % of (C) a polyol resin having a hydroxyl group value of from 30 to 120 mgKOH/g and a weight average molecular weight from 5,000 to 50,000, from 0.5 to 12 mass % of (D) a diol having a weight average molecular weight of from 120 to 1,000 and from 0.01 to 1.5 mass % of (E) a hardening catalyst, wherein the proportions are with respect to the total mass of the resin solid fraction of the (A), (B), and (C) components.
US08728575B2 Method for synthesizing a thin film
A method for synthesizing a thin film, the method containing the steps of: (a) providing a substrate support assembly containing at least two selectively interdigitable substrate support fixtures; (b) loading a substrate for thin film synthesis onto said at least two fixtures; (c) interdigitating said at least two fixtures; (d) positioning said at least two fixtures in a reaction chamber and forming a thin film on a surface of the substrate; and (e) unloading the substrate from said at least two fixtures.
US08728573B2 Metal compound coated particulate mineral materials, methods of making them and uses thereof
Particulate mineral materials comprising at least one coating comprising at least one metal compound are disclosed. In one embodiment, the at least one metal compound is a metal silicate compound. In another embodiment, the at least one metal compound is a metal oxide compound. In one embodiment, the particulate mineral material is perlite. In another embodiment, the particulate mineral material is perlite microspheres. In a further embodiment, the particulate mineral material is diatomite. Methods of making particulate mineral materials coated with at least one metal compound are also disclosed. In one embodiment, the at least one metal compound may be injected into a perlite expander to form a metal compound coated perlite material. In another embodiment, the at least one metal compound may be applied through a low temperature coating process to the at least one particulate mineral material. Uses for metal compound coated particulate mineral materials are also disclosed.
US08728568B2 Method for encapsulation of electronics received in water meter pits with an improved wax-based encapsulant/moisture barrier
The presently disclosed subject matter is directed to method for forming an encapsulant and coating electronic components such as those utilized in AMR technology with the encapsulant. The encapsulant comprises a wax, a tackifier, a polymer, a plasticizer, a thixotropic agent, and an antioxidant and is designed to protect electronic components from harsh environments such as those where high levels of humidity or corrosive liquids may be present. For example, the encapsulant exhibits minimal percent weight gain due to moisture vapor when subjected to temperatures ranging from about −40° C. to about 70° C. and relative humidities ranging from 0% to 85% over a period of 200 days.
US08728564B2 Powder mix and a method for producing a building panel
A powder mix layer for a building panel and a method for producing a building panel with a decorative surface produced from a powder mix layer with a controlled loss on cure.
US08728559B2 Pet food compositions
Disclosed herein are pet food compositions. In one embodiment, pet food compositions which are described comprise a component selected from 2-deoxy-D-glucose; 5-thio-D-glucose; 3-O-methylglucose; 1,5-anhydro-D-glucitol; 2,5-anhydro-D-mannitol; mannoheptulose; and mixtures thereof. In yet another embodiment, pet food compositions which are described comprise an extract of plant matter selected from avocado, alfalfa, fig, primrose, and mixtures thereof. The pet food compositions may be prepared by any of a variety of processes including, but not limited to, optional processes described herein.
US08728558B2 Process for the production of a foodstuff containing a fat carrier, a stabilizer and a solvent for said stabilizer
A process for the production of a foodstuff containing a fat carrier, a stabilizer and a solvent for the stabilizer, the fat carrier comprising vegetable fat contents having a solid consistency at room temperature comprising dissolving the stabilizer in the solvent, soaking the mixture containing the solvent and the stabilizer in a warmed state for between 15 and 45 minutes at a temperature of between 10 degrees Celsius and 35 degrees Celsius, heating the vegetable fat contents to a temperature between 2% and 20% above their melting point, and mixing the fat carrier to the mixture containing the solvent and the stabilizer in liquid form.
US08728556B2 Hydrolysed protein-polysaccharide complexes
The present invention relates to hydrolysed protein-polysaccharide complexes, and more specifically to those complexes formed by complex formation of a protein with a polysaccharide followed by hydrolysis. The resulting complexes have good emulsifying and stabilizing properties and can be used in food, cosmetic or pharmaceutical products. The invention further relates to the method of manufacture of such complexes.
US08728547B2 Formulations and methods for increasing metabolic rate and weight control
The invention provides methods for increasing resting metabolic rate, reducing waist circumference, and weight control by administering a composition comprising dietary fiber, phenylalanine, tyrosine, tea blend, caffeine, and Lycium plants or Lycium plant extract preparations to the subject. The invention also provides a food or dietary supplement formulation which contains dietary fiber, phenylalanine, tyrosine, tea blend, caffeine, and Lycium plants or Lycium plant extract preparations.
US08728545B2 Extraction method for providing an organic certifiable Stevia rebaudiana extract
A simple extraction method for preparing an organic certifiable stevia extract with high sweetness and optionally with antioxidant properties is provided. The extraction method involves extraction of stevia leaves that have been dried and grinded with a hot solvent generally regarded as safe (GRAS), allowing the dissolution of the sweetening compounds naturally present therein. These sweetening compounds include steviosides and rebaudioside A, which are purified from the extracts by two or more successive chromatographic purifications steps. The sweetening compounds are then eluted with an appropriate elution solvent. The simplicity and organic certification of the method provide advantages over the methods currently employed in the stevia industry.
US08728544B1 Sonically formed trichomic extract material
A process, product, and product by process related to sonic welding, for quickly, compressing, shaping, and decarboxylating cannabinoids; preferably from Cannabis; for oral ingestion without using any liquids or solvents; such process breaks down the Cannabis plant's cellulosic structure; increasing oil extraction; while compaction decreases transportation and storage costs, making the end product desirable as an additional ingredient in other edibles.
US08728539B2 Method of enhancing intestinal pinocytosis of immunoglobulins in postnatal domestic mammals
Disclosed is a method of enhancing absorption (pinocytosis efficiecy) of immunoglobulins administered to postnatal domestic mammals (e.g., bovine) by using selenium. As an example of a selenium compound added, sodium selenite is particularly effective.
US08728537B2 Compositions for improvement of wound healing
This invention relates to aqueous solutions of reactive chlorine compounds having the empirical formulae H2Cl2O6 or ClO3H, for example, and the derivatives, anions or salts thereof. The invention further relates to methods for the production of said compounds and the use thereof in the pharmaceutical and particularly in the medical field, in cosmetics, medicinal care and in the domains of food technology and technology.
US08728536B2 Chemotherapeutic composition using nanocrystalline calcium phosphate paste
A method and composition are provided for treating cancer in a mammal. The method includes administering to a tumor site of the mammal an anticancer composition comprising a mixture of an anticancer agent and a nanocrystalline or poorly crystalline calcium phosphate paste, said paste comprised of one or more calcium phosphates and a physiologically acceptable fluid, the paste having an injectable or formable consistency at the time of administration and hardenable at the tumor.
US08728531B2 Composition and method to improve blood lipid profiles and optionally reduce low density lipoprotein (LDL) per-oxidation in humans
A composition and method which improves blood lipid profiles and optionally reduces low density lipoprotein (LDL) per-oxidation in humans by administering a therapeutic amount of a composition comprising krill oil in combination with astaxanthin or a mixture of fish oil derived, choline based, phospholipid bound omega-3 fatty acid mixture including phospholipid bound polyunsaturated EPA and DHA. In one embodiment, the krill oil is derived from Euphasia spp., comprising Eicosapentaenoic (EPA) and Docosahexaenoic (DHA) fatty acids in the form of triacylglycerides and phospholipids. The krill oil includes at least 10% EPA and 5% DHA, of which greater than 50% are in the form of phospholipids and the 1-4000 mg of krill oil per daily dose is delivered.
US08728528B2 Process for preparing microparticles having a low residual solvent volume
The disclosed processes for forming microparticles utilize low volumes of processing water while still providing microparticles having low residual solvent levels. The processes are adaptable to both continuous and batch processes using oil/water or water/oil or water/oil/water or oil/water/oil emulsions.
US08728527B2 Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
The present invention belongs to the fields of pharmacology, medicine and medicinal chemistry. The present invention provides novel pharmaceutical compositions composed of solid nanoparticles dispersed in aqueous medium of substantially water insoluble pharmaceutical substances such as docetaxel with reduced Ostwald ripening.
US08728524B2 Biomaterials consisting of sulphated hyaluronic acid and gellan to be used in the prevention of spinal adhesions
New biomaterials consisting of a combination of sulphated hyaluronic acid and gellan (as well as gellan that has not been associated with other polymers), to be used as a highly effective barrier to prevent post-surgical adhesions in abdominal, pelvic and, above all, spine surgery.
US08728520B2 Cross-linked alginate-polyalkylene glycol polymer coatings for encapsulation and methods of making the same
A biocompatible capsule comprising a biological material encapsulated by a covalently stabilized coating and a method of making the same are disclosed. The biological material can be a material selected from the group consisting of cells, such as islets of Langerhans, pharmaceuticals, and biological agents. The coating can be formed by reacting an alginate-[polyalkylene glycol (PAG)-X1]n, and a multi-functional PAG-X2, to form covalent bonds, wherein n is an integer greater than 0, a first one of X1 and X2 is N3, and a second one of X1 and X2 is selected from the group consisting of: wherein R1=CH3, CH2CH3, CH(CH3)2, R2=N(CH3)2, OCH3, OH, CH3, H, F, Cl, Br or NO2, and R3=OCH3, CH3, H, F, Cl or NO2.
US08728517B2 Pharmaceutical compositions of entacapone co-micronized with sugar alcohols
The present invention relates to pharmaceutical compositions comprising entacapone or pharmaceutically acceptable salts thereof along with one or more sugar alcohols; wherein the entacapone is co-micronized with one or more sugar alcohols. The invention also relates to processes of making such compositions.
US08728516B2 Stabilized lipid formulation of apoptosis promoter
An orally deliverable pharmaceutical composition comprises a Bcl-2 family protein inhibitory compound, e.g., ABT-263, a heavier-chalcogen antioxidant and a substantially non-aqueous lipid carrier, wherein said compound and said antioxidant are in solution in the carrier. The composition is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.
US08728508B2 Hydrophilic coating and a method for the preparation thereof
The present invention provides a method for the preparation of a cross-linked hydrophilic coating of a hydrophilic polymer on a substrate polymer surface of a medical device, involving the use of a polymer solution comprising 1-20% by weight of a hydrophilic polymer, 0-5% by weight of additive(s), and the balance of a vehicle with plasticizing effect on the hydrophilic polymer, wherein the vehicle comprises at least one plasticizer having a solubility in water of at least 6 g/L, a boiling point above 210° C. at 760 mmHg, and Hansen δH parameter of less than 20. Furthermore, the invention provides a medical device, e.g. a catheter or guide wire, provided with such a hydrophilic coating. The invention also provides the use of specific polymer solution for the preparation of a cross-linked hydrophilic coating.
US08728506B2 Durable pest repellent and pest repellent resin composition
Disclosed is a pest repellent that has excellent heat resistance and solvent resistance, that can be kneaded into a resin molded article or a synthetic fiber, and that has excellent durability and persistence for which a pest repellent effect is sustained for a long period even when it is used for a long period or washed. A durable pest repellent that has both high heat resistance and persistence has been accomplished by supporting on a specific layered silicate a pest repellent chemical containing as an essential component at least one selected from N,N-diethyl-m-toluamide, 1-piperidinecarboxylic acid-2-(2-hydroxyethyl)-1-methylpropyl ester, and N,N-diethyl-m-toluamide and 1-piperidinecarboxylic acid-2-(2-hydroxyethyl)-1-methylpropyl ester.
US08728503B2 Emulsion cosmetic
Provided is an emulsified cosmetic composition having an excellent UV-protective effect, an excellent transparent feeling, an excellent feeling upon application, and an excellent long-term stability. The emulsified cosmetic composition is characterized by containing a powder which is produced by subjecting a zinc oxide powder (A) having an average particle diameter of 0.1 to 1 μm, an average particle thickness of 0.01 to 0.2 μm, and an average aspect ratio of 3 or more to surface treatment with a silane or silazane compound having a C1-20 alkyl or fluoroalkyl group and having reactivity with an inorganic oxide.
US08728501B2 Composite material of inorganic nonmetallic mineral loaded with titania layer, preparation process and use thereof
The invention discloses composite materials, comprising an inorganic nonmetallic mineral as a support and a nanotitania layer loaded on the support, wherein the layer is comprised of a plurality of titania nanospheres, and the titania nanosphere is comprised of a plurality of nanotitania single particles. The invention also discloses composite materials further comprising one or more functional layers loaded on the nanotitania layer. The above composite materials may not only take advantage of the high refractive index and the high covering power of the nanotitania layer, but also make use of the good photocatalytic activity of the small single nanoparticles. Furthermore, the composite materials can be more readily coated by other functional layer(s) to prepare functionally strengthened or multi-functional composite materials. The invention also discloses methods for preparing the composite materials. The composite materials may be used as an additive with good compatibility in various industrial fields.
US08728500B2 Composition containing a polyorganosiloxane polymer, a thickening agent and at least one volatile alcohol
The invention relates to a physiologically acceptable composition, especially a cosmetic composition, comprising (a) at least one polyorganosiloxane containing polymer comprising at least one moiety which comprises at least one polyorganosiloxane group consisting of 1 to about 1000 organosiloxane units in the chain of the moiety or in the form of graft, and at least two groups capable of establishing hydrogen interactions; (b) at least one volatile alcohol; and (c) at least one thickening agent, as well as to methods of using such compositions and kits containing such compositions.
US08728499B2 Dendritic macroporous hydrogels prepared by crystal templating
The present invention includes a hydrogel and a method of making a porous hydrogel by preparing an aqueous mixture of an uncrosslinked polymer and a crystallizable molecule; casting the mixture into a vessel; allowing the cast mixture to dry to form an amorphous hydrogel film; seeding the cast mixture with a seed crystal of the crystallizable molecule; growing the crystallizable molecule into a crystal structure within the uncrosslinked polymer; crosslinking the polymer around the crystal structure under conditions in which the crystal structure within the crosslinked polymer is maintained; and dissolving the crystals within the crosslinked polymer to form the porous hydrogel.
US08728484B2 Vaccine for runting-stunting syndrome
The present invention includes polypeptides, polynucleotides, antibodies, and vaccines associated with Runting Stunting Syndrome (RSS) in poultry. The present invention also includes diagnostic methods based on such polypeptides, polynucleotides, and antibodies and methods of protecting poultry, including chickens, against RSS by the administration of such polypeptides, polynucleotides, antibodies, and vaccines.
US08728482B2 Humanized antibodies against TL1A
Disclosed are humanized antibodies that bind specifically to TNF superfamily member 15 (TNFSF15), also known as TL1A. Methods of making and using the anti-TL1A antibodies are also described. The humanized antibodies may be antagonists and may used to treat or diagnose conditions associated with TL1A function.
US08728473B2 Methods of preventing or treating pain using anti-NGF antibodies
Antibodies and antibody fragments thereof with binding specificity to human Nerve Growth Factor (NGF) and methods of use for treating pain. Methods of treating pain or eliciting an analgesic effect comprising administering an effective amount of an anti-human NGF antibody or antibody fragment thereof, which inhibits the association of NGF with TrkA, and/or p75. These methods may optionally further comprising administering an effective amount of a second anti-human NGF antibody or fragment thereof (e.g., one which inhibits the association of NGF with p75, or one that inhibits the association of NGF with TrkA.)
US08728471B2 Antibody therapy for treatment of diseases associated with gluten intolerance
The present invention includes a pharmaceutical compositions and methods for treating diseases associated with gluten intolerance in a patient, comprising: administering to the patient an effective amount of an antibody having specific activity against gluten or gluten-derived peptides. Such diseases include, for example, celiac disease and dermatitis herpetiformis.
US08728470B2 CAB molecules
The present invention relates to CAB molecules, ADEPT constructs directed against CEA, and their use in therapy.
US08728468B2 Treatments for cancer
The present invention provides methods for reducing tumor survival, expansion, and metastasis. In particular, the invention provides methods for reducing melanoma tumor survival, expansion, and metastasis. The invention also provides agents for use in the methods, particularly agents that reduce the level or activity of connective tissue growth factor (CTGF).
US08728463B2 Production of tissue engineered digits and limbs
The invention pertains to methods of producing artificial composite tissue constructs that permit coordinated motion. Biocompatable structural matrices having sufficient rigidity to provide structural support for cartilage-forming cells and bone-forming cells are used. Biocompatable flexible matrices seeded with muscle cells are joined to the structural matrices to produce artificial composite tissue constructs that are capable of coordinated motion.
US08728461B2 Lactic acid bacterium having high immunoglobulin-A-inducing ability
A novel lactic acid bacterium strain is found, which has a high IgA production-inducing ability and a high immunostimulating activity, and belongs to the genus Enterococcus. Thus, provided is an excellent lactic acid bacterium preparation for foods or feeds, which has a high enteric colonization rate. Specifically disclosed are: a novel lactic acid bacterium Enterococcus faecium NHRD IHARA (FERM BP-11090) which has a high IgA production-inducing ability and a high immunostimulating activity; and a lactic acid bacterium preparation for enhancing the production of immunoglobulin A, which comprises a culture of the bacterium strain, an extract of the bacterium strain, or a product of any treatment of cells of the bacterium strain.
US08728459B2 Bacteria and method for controlling plant disease using the same
An object of the present invention is to provide a means for imparting resistance against pathogenic fungal, pathogenic bacterial, or pathogenic viral disease to agriculturally useful plants. The present invention relates to a bacterium belonging to the genus Azospirillum or the genus Herbaspirillum capable of imparting resistance against pathogenic fungal, pathogenic bacterial, or pathogenic viral disease to a host plant by living symbiotically within the plant, a method for controlling plant disease using the bacteria, and plants produced by such method.
US08728457B2 Methods of inducing differentiation of stem cells
The present invention relates to methods of inducing differentiation of stem cells. In particular, the invention relates to methods of inducing differentiation of embryonic stem cells into muscle cells or vascular endothelial cells. The invention also includes cells, cell lines, testing models and culture systems used in the methods of the present invention and differentiated cells produced therefrom. The present invention also provides methods of using the differentiated cells of the present invention for therapeutic purposes.
US08728452B2 Aqueous fatty monoamine-containing systems for water-insoluble materials
The present invention is drawn to an aqueous composition containing: (a) at least one fatty monoamine; (b) at least one nonionic surfactant; (c) at least one compound chosen from an alkyl ether carboxylic acid, an alkyl ether carboxylate, a fatty acid having from about 6 to about 40 carbon atoms, and mixtures thereof; and (d) at least one water-insoluble material, and wherein the composition is homogeneous and clear to substantially clear in appearance.
US08728451B2 Styling composition comprising, in a predominantly aqueous medium, a pseudo-block polymer, processes employing same and uses thereof
The disclosure provides styling cosmetic compositions comprising, in a cosmetically acceptable medium predominantly comprising water, at least one pseudo-block polymer, cosmetic treatment processes for shaping and/or holding the hairstyle employing the cosmetic compositions and also to uses of the cosmetic compositions for obtaining shaping of the hair that is persistent over time and shaping of the hair that is moisture-resistant.
US08728450B2 Hair conditioning composition comprising quaternized silicone polymer, grafted silicone copolyol, and dialkyl cationic surfactant
Disclosed is a hair conditioning composition comprising: (a) a quaternized silicone polymer; (b) a grafted silicone copolyol; (c) a cationic surfactant system comprising a dialkyl quaternized ammonium salt cationic surfactant; (d) a high melting point fatty compound; and (e) an aqueous carrier. The present invention can provide improved conditioning benefits such as smooth feel and reduced friction in conditioning compositions using dialkyl quaternized ammonium salt cationic surfactants.
US08728447B2 Teeth-whitening gel
A teeth-whitening gel is provided. The main ingredient of the teeth-whitening gel comprises a polypeptide having halamine (N—X bond, X═Cl, Br or I) groups and a high molecular weight. By the redox properties of halamine group, the gel contacting with the teeth's surface can bleach and whiten the teeth.
US08728446B2 Oral hygiene tablets and capsules for direct oral delivery of active ingredients
An oral hygiene tablet or capsule for direct oral delivery of active ingredients to humans and animals is provided composed of a tablet or capsule having an outer shell and inner cavity containing an active ingredient. Active ingredients contained and delivered by the oral hygiene tablet include mouthwash, toothpaste, medicament, mouth soothing and numbing agents, fluoride rinse, joint preserving agents, vitamins and herbal supplements. Other ingredients, such as flavor enhancers, scents, colorings and sugars may be included in the composition of the tablet or capsule. Delivery of the supplement ingredients is effectuated by simply placing the tablet into the mouth and allowing saliva to cause the outer shell to dissolve. The dissolution process can be accelerated by biting of the tablet/capsule and breaking it into smaller particles and/or by drinking water when the tablet is inserted into the mouth.
US08728443B2 Formulation comprising nicotine and a cation exchange resin
A method of producing a nicotine delivery product includes a mixture having nicotine, a cation exchange resin and water. The water content of the mixture is between 5 and 75 wt. % relative to the whole mixture. The mixture is combined with further components of the nicotine delivery product.
US08728442B2 Method of controlling the growth of microorganisms by a composition containing isolated or in vitro synthesized nitrosoamides
The present invention relates to novel compounds and compositions and the use of them for the control of fungal and bacterial pathogens, insect pests, acari, nematodes and other invertebrate pests including, but not limited to post-harvest and soil diseases, building mold remediation, and seed and grain sanitation.
US08728441B2 Sublingual buccal effervescent
A pharmaceutical dosage form adapted to supply a medicament to the oral cavity for buccal, sublingual or gingival absorption of the medicament which contains an orally administrable medicament in combination with an effervescent for use in promoting absorption of the medicament in the oral cavity. The use of an additional pH adjusting substance in combination with the effervescent for promoting the absorption drugs is also disclosed.
US08728440B2 Nanoparticulate compositions for diagnostic imaging
The present invention provides a trialkoxysilanes having structure I wherein R1 and R2 are independently at each occurrence a C1-C3 alkyl group; R3 is independently at each occurrence a hydrogen or a C1-C3 alkyl group; R4 is a C1-C5 aliphatic radical, a C7-C12 aromatic radical, or a C5-C10 cycloaliphatic group; n is 0, 1, 2 or 3; q is 1, 2 or 3; and X− represents a charge balancing counterion. The trialkoxysilanes are useful for the preparation of nanoparticulate diagnostic imaging agent compositions.
US08728438B2 Coronin 1 modulators for the treatment of autoimmune and lymphoproliferative disorders and mycobacterial infections
The invention relates to the treatment of mycobacterial infections, autoimmune disorders, lymphoproliferative disorders and induction of immunosuppression following transplantation using coronin 1 and modulators of coronin 1. Particular modulators of coronin 1 are compounds which inhibit the production of coronin 1 or the formation of active coronin 1 from a coronin 1 precursor, partly or entirely inactivate coronin 1, inhibit concentration of coronin 1 at the site of T cell activation, or inhibit the coronin 1 mediated signaling pathway downstream of the T cell receptor. Examples of such modulators are antibody or antibody fragments, coronin 1 peptide fragments or corresponding phosphopeptides, or anti-sense oligonucleotides, e.g. siRNA or shRNA. The invention further relates to a method of screening for a compound effective in the treatment of mycobacterial infections, autoimmune disorders, lymphoproliferative disorders and induction of immunosuppression following transplantation comprising contacting a candidate compound with coronin 1 or coronin 1 expressing cells, and selecting appropriate compounds.
US08728432B2 Process for producing dispersion of surface-treated carbon black powder, and process for producing surface-treated carbon black powder
A method of producing a surface-treated carbon black powder dispersion includes subjecting carbon black fine particles having a volume average particle size of 100 nm to 20 μm to wet granulation and drying by heating to obtain granulated carbon black having a hardness of 12 cN or less and a pH of less than 7, grinding the granulated carbon black to obtain a ground product having a volume average particle size of 20 nm to 20 μm, and subjecting the ground product to wet oxidization in an aqueous medium. The resulting surface-treated carbon black powder dispersion exhibits excellent print density, print quality, discharge stability, and storage stability when used as an inkjet printer aqueous black ink.
US08728431B2 Method of preparing carbon nanotubes and catalyst for producing carbon nanotubes
A method for preparing carbon nanotubes including attaching a catalyst consisting of a compound in which a transition metal element of Group 8, 9 or 10 is coordinated to a nitrogen-containing dendrimer compound having at least one nitrogen atom, to which a metal element may be coordinated, on a surface of a substrate, and thermally decomposing a carbon compound in the vicinity of the substrate while supplying the carbon compound on the surface of the substrate to which the catalyst is attached. The catalyst for producing the carbon nanotubes is a compound in which a transition metal element of Group 8, 9 or 10 is coordinated to a nitrogen-containing dendrimer compound having at least one nitrogen atom to which a metal element may be coordinated.
US08728430B2 Low temperature single-wall carbon nanotube synthesis
The present disclosure is directed to a method for producing SWCNT from endothermic carbon-containing feedstock, such as, methane gas, using an activated alumina supported Fe:Mo catalyst. The SWCNT growth temperature is less than about 560° C., and the catalyst is activated by exposure to a reducing atmosphere at a temperature greater than about 900° C.
US08728427B2 Method for the manufacture of concentrated phosphorus acid
A method for the manufacture of concentrated phosphorous acid starting from pure P4O6 is disclosed. The P4O6 is hydrolyzed, preferably under stirring in water in the presence of a homogeneous Broensted acid catalyst while maintaining in the hydrolysis/reaction medium a pH below 5 whereby the free water level, at the completion of the hydrolysis, is in the range from 0 to 40%.