Document Document Title
US08723485B2 Power supply system
A power supply system includes an output node, an internal power supply unit, a boost storage unit, a charging path unit, and a discharging path unit. The output node is coupled to a load device. The internal power supply unit includes a gold capacitor unit for storing an internal storage voltage. The charging path unit is turned on in a charging period to store a boost supply voltage in the boost storage unit. The discharging path is turned on in a discharging period to provide a power signal for drive the load device according to the internal storage voltage and the boost supply voltage. The charging and discharging periods are non-overlapping.
US08723484B2 Method and apparatus for controlling charging and discharging of a battery used in a base station
A method and a apparatus for controlling charging and discharging of a battery used in the base station are provided. The method includes the following steps: obtaining configuration parameters in the base station that are used for controlling the charging and the discharging of the battery used in the base station, and controlling the charging and the discharging of the battery used in the base station according to current time and the configuration parameters.
US08723483B2 Battery monitoring device
There is disclosed a battery monitoring device including a voltage equalization circuit that equalizes cell voltages of a plurality of battery cells being connected in series and forming a battery pack, and a microcomputer that outputs an instruction signal to instruct the voltage equalization circuit to start an voltage equalizing operation for the battery cells. The microcomputer includes a first timer section that stops the voltage equalizing operation a first predetermined set time after the start of the voltage equalizing operation, and the voltage equalization circuit includes a second timer section that stops the voltage equalizing operation a second predetermined set time after the start of the voltage equalizing operation. This can enhance reliability during the voltage equalizing operation.
US08723479B2 Battery pack, charger, and charging system that protects rechargeable batteries against a malfunctioning protection circuit
A battery pack, a charger, and a charging system. The battery pack includes a rechargeable battery, and a protection circuit to control charging and discharging of the battery, wherein the protection circuit includes a micom to output an operating state signal representing an operating state of the micom and a malfunction transferring unit to transfer information on whether the battery is malfunctioning based on the operating state signal. Accordingly, when an error is detected by the protection circuit of the battery pack, charging is stopped, and thus the battery pack may be stably charged.
US08723478B2 Automatic and dynamic home electricity load balancing for the purpose of EV charging
A charging station for electric vehicles receives customer bids on a charging time interval allotment, compares the customer bids, and supplies electric current from the charging station to a plurality of electric vehicles allocated to each electric vehicle according to the bids.
US08723477B2 Charging cable connector for connecting an electric vehicle to a charging station
The invention relates to a plug device for a charging cable for connecting an electric vehicle to a charging station, comprising a housing, electrical contacts associated with the housing for connecting to a connecting device in the charging station or in the electric vehicle, and a coding means arranged in the housing for the value of the amperage which may be transmitted via the charging cable. The invention further relates to a system consisting of a charging cable and a charging station and/or an electric vehicle as well as a charging cable equipped with the plug device.
US08723474B2 Electrical vehicle energy system and operating method thereof
An electric vehicle energy system is provided. The electrical vehicle energy system includes an electrical control unit used for producing the electric vehicle mode according to the external input signals. The electrical vehicle energy further includes an energy storage system used for producing a motor control signal according to an electric vehicle mode. The power loop structure includes at least a first power module and a second power module. The structure further includes at least a first detector and a second detector used for producing a first detecting signal and a second detecting signal according to the first power module and the second power module. The power loop structure further includes an energy storage controller used for producing the plurality of switch control signals according to the electric vehicle mode, the first detecting signal and the second detecting signal through a control area network by a voltage-difference hysteresis operation.
US08723472B2 Servo control device
Improved precision is realized in positioning control. Provided is a servo control device that is applied to a numerical control equipment provided with a screw-feeding section that converts rotational movement of a motor to linear movement, a driven section that is linearly moved by the screw-feeding section, and a support member by which the screw-feeding section and the driven section are supported and that controls the motor so as to match a position of the driven section to a positioning instruction, including a support-member-reaction-force compensating section 311 that compensates for vibrations of the driven section due to a vibrational reaction force of the support member, wherein a transfer function provided in the support-member-reaction-force compensating section 311 includes a stiffness term for the driven section.
US08723469B2 Motor winding overheat prevention apparatus and motor control apparatus
A winding overheat prevention apparatus comprises: a stator winding temperature calculation unit which calculates winding temperature based on the ambient temperature of the motor and on the amount of change in the estimated temperature of a stator winding; a position sensor temperature detection unit which detects the temperature indicated by a temperature sensing element in a position sensor a rotor; and an alarm signal output unit which outputs an alarm signal when the winding temperature exceeds an alarm level, wherein when the ambient temperature is not higher than a prescribed temperature, the alarm level is set equal to a temperature preset based on the ambient temperature and the maximum value of the amount of the temperature change, while when the ambient temperature is higher than the prescribed temperature, the alarm level is set equal to a temperature preset in order to protect the position sensor from overheating.
US08723466B2 Motorized venetian blind system
A motorized venetian blind system for covering a window of a space comprising a blind drive unit having two motors to provide for independent control of a position of a bottom rail and a tilt angle of a plurality of slats of the blind system. The blind drive unit is operable to adjust the position of the bottom rail to a preset position, and to adjust the tilt angle of the slats to a preset angle in response to receiving a single digital message (e.g., a preset command). The blind drive unit is operable to automatically adjust the position of the bottom rail and the tilt angle of the slats to limit a direct sunlight penetration distance in the space to a maximum direct sunlight penetration distance, and to maximum a reflected sunlight penetration distance on a ceiling of the space, while minimizing occupant distractions.
US08723465B2 Blade pitch controlling drive for a wind turbine
The invention relates to a blade pitch controlling drive for a wind turbine, comprising an electrical converter, an electric motor that is electrically coupled to the converter, a monitoring unit operable to monitor an electric output current supplied by the converter to the electric motor and determine a state of the load on the converter as a function of the electrical output current, a current limiting unit operable to reduce a maximum possible output current to a nominal current when the state of the load is an overload state when the nominal current when in a non-overload state, and a peak current control unit that can be activated. When activated, the peak current may be provided as the maximum possible output current, regardless of the load state of the inverter at the time of the activation.
US08723463B2 Motor control apparatus and method thereof
A motor control apparatus includes a phase sensing circuit, a current sensing circuit, a controller and a driving circuit. The driving circuit receives a first driving signal and then controls a phase switching state of the magnetic pole of the motor so as to drive the motor in accordance with the first driving signal. The phase sensing circuit detects the phase switching state of the magnetic pole to generate and output a phase switching signal to the controller during the motor is operating. The current sensing circuit detects a current flowing through the motor to generate and output a current phase signal to the controller. The controller compares a phase difference between the phase switching signal and the current phase signal to generate and output a second driving signal to the driving circuit. The driving circuit controls the phase switching state of the magnetic pole for driving the motor in accordance with the second driving signal.
US08723462B2 Methods, systems and apparatus for estimating angular position and/or angular velocity of a rotor of an electric machine
Embodiments of the present disclosure relate to methods, systems and apparatus for estimating angular position and/or angular velocity of a rotor of an electric machine.
US08723459B2 Method and arrangement for controlling permanent magnet synchronous machines
A method and an arrangement are provided for controlling a sensorless permanent magnet synchronous machine using a frequency converter connected to feed the machine with electrical power. A current vector having a magnitude is produced to the stator of the machine with the frequency converter, and the current vector is rotated for rotating the rotor of the machine. Prior to starting the drive, a value is defined for the magnitude of the current vector and a frequency limit. The defined value is used as the magnitude of the current vector when the rotor of the machine is rotated with a frequency that is lower than the defined frequency limit. A vector control method is used for controlling the machine when the frequency of the machine is higher than or equal to the defined frequency limit.
US08723458B1 Soft start drive for mobile refrigeration unit
A system for driving a three phase motor using a variable speed drive in communication with an alternator driven by a prime mover. A rectifier can be connected with the alternator. The system can also include a logic and alternator field drive configured to sense voltage leaving the rectifier and controlling the alternator to maintain a predetermined output from the rectifier.
US08723454B2 Motor arrangement for window coverings
The present invention relates to an architectural window covering having a programmable electric motor. The programmable electric motor is housed within a roller for raising and lowering the window covering, and includes dual stacked motors and light-transmitting control actuation buttons In one embodiment an architectural window covering, composing a shade, a roller defining a bore coupled to the shade, and at least two motors axially aligned and electrically coupled in parallel and positioned at least partially in said bore and rotatably coupled to the roller is disclosed.
US08723452B2 D.C. charged particle accelerator and a method of accelerating charged particles
A d. c. charged particle accelerator comprises accelerator electrodes separated by insulating spacers defining acceleration gaps between adjacent pairs of electrodes. Individually regulated gap voltages are applied across each adjacent pair of accelerator electrodes. In an embodiment, direct connections are provided to gap electrodes from the stage points of a multistage Cockcroft Walton type voltage multiplier circuit. The described embodiment enables an ion beam to be accelerated to high energies and high beam currents, with good accelerator stability.
US08723445B2 Light power compensation device, light power compensation circuit, and detecting module
A light power compensation circuit includes a current source to be electrically coupled to a temperature-detecting light-emitting device and providing a working current for the temperature-detecting light-emitting device, a detector unit operable to detect a forward bias voltage across the temperature-detecting light-emitting device and providing a detector voltage proportional to the forward bias voltage, a compensation voltage converting module converting the detector voltage into a compensation voltage which has a negative relation to change in the detector voltage, and a driving module converting the compensation voltage into a driving current which is proportional to the compensation voltage and which drives operation of a controlled light-emitting device.
US08723444B2 Electrical load driving circuit
Circuits and methods for driving electrical loads, where each is driven according to a desired current. A circuit comprising a switch mode converter comprising a transformer with primary and secondary windings, the primary connected to a voltage supply via one or more input control switches; output circuits, each comprising a switch connecting a load to an output of the secondary, each load series connected with a respective switch and in parallel with a capacitor; and a switching control circuit for control of each of the output circuit switches and for sensing a current through the loads. The switching control circuit operates the output circuit switches to maintain set current through the loads, the switching control circuit configured in successive output cycles of the switch mode converter to operate each output circuit switch in an order dependent on a forward voltage of each of the respective loads.
US08723443B2 Method of controlling an LED, and an LED controller
A method is disclosed of controlling a LED, comprising driving the LED with a DC current for a first time, interrupting the DC current for a second time such that the first time and the second time sum to a period, determining at least one characteristic of the LED while the DC current is interrupted, and controlling the DC current during a subsequent period in dependence on the at least one characteristic. The invention thus benefits from the simplicity of DC operation. By operating at the LED in a DC mode, rather than say in a PWM mode, the requirement to be able to adjust the duty cycle is avoided. By including interruptions to the DC current, it is possible to utilize the LED itself to act as a sensor in order to determine a characteristic of the LED. The need for additional sensors is thereby avoided.
US08723437B1 Filter bandwidth adjustment in a multi-loop dimmer control circuit
The embodiments disclosed herein describe the adjusting of filter bandwidths in a multi-loop LED dimmer control circuit based on received dimmer input signals. The bandwidth of a filter in an active loop (a loop driving an LED power circuit) is decreased to prevent signal noise and associated LED flickering. Likewise, the bandwidth of a filter in an inactive loop (a loop not driving the LED power circuit) is increased to a pre-determined maximum in order to improve response time and decrease potential overshoot or undershoot during dimmer adjustment.
US08723436B2 LED lighting device and illumination apparatus including same
An LED lighting device includes two or more switching circuits connected between a power source and an LED (light emitting diode) unit, an inrush current limiting circuit which limits an inrush current flowing through the LED lighting device when power is turned on and a trigger circuit which generates a trigger signal of an operation/non-operation of the inrush current limiting circuit from the switching circuits. Further, the inrush current limiting circuit is set in a non-operation state when any one of the switching circuits is started first.
US08723432B2 Capacitive full-wave circuit for LED light strings
A capacitive full-wave circuit for LED light strings makes use of capacitors and diodes together to drive a LED string with full AC waves. Different from the conventional four-diode full-wave rectifying circuit, one embodiment of capacitive full-wave circuit includes two capacitors and two diodes. Because of the large imaginary impedance, the capacitors not only limit and the voltage and current through the LEDs, but also consume almost no electrical power. The electrical current-voltage performance can be further improved by introducing four resistors with a cost of some additional power consumption. A LED light string module with the capacitive full-wave circuit is also presented, with the capacitive full-wave circuit integrated inside of a front power plug and a back power socket.
US08723428B2 LED power source with over-voltage protection
A resonant DC-DC converter used to drive an LED array includes a half-bridge converter configured to receive DC input power and produce a square wave voltage. A resonant tank circuit that includes an inductive element, a first resonance capacitor, and a second resonance capacitor, is coupled to the half-bridge converter to receive the square wave voltage such that a generally sinusoidal AC voltage is produced across the second resonance capacitor. An output transformer with a primary winding and one or more secondary windings, is coupled in parallel to the second resonance capacitor, and a clipping circuit is coupled to the primary winding such that the voltage across the primary winding does not substantially exceed the voltage of the DC input power. An output rectifier is coupled to the one or more secondary windings of the output transformer and is configured to produce a generally DC output voltage.
US08723425B2 Light emitting diode driver circuit
The present teachings provide a device and method of regulating current flow across an array of emitting diodes (LEDs) for the purpose of illumination. The device has a power supply (vext) connected to an LED array. The LED array is connected to a current foldback element, a current limitation element, a current sensing element, and a current switch. Current through the array of light emitting diodes achieves an upper current level, the current sensing element signals activation of the current limitation element, said current limitation element maintains current through the array of light emitting diodes at approximately the upper control limit.
US08723422B2 Systems and methods for cylindrical hall thrusters with independently controllable ionization and acceleration stages
Systems and methods may be provided for cylindrical Hall thrusters with independently controllable ionization and acceleration stages. The systems and methods may include a cylindrical channel having a center axial direction, a gas inlet for directing ionizable gas to an ionization section of the cylindrical channel, an ionization device that ionizes at least a portion of the ionizable gas within the ionization section to generate ionized gas, and an acceleration device distinct from the ionization device. The acceleration device may provide an axial electric field for an acceleration section of the cylindrical channel to accelerate the ionized gas through the acceleration section, where the axial electric field has an axial direction in relation to the center axial direction. The ionization section and the acceleration section of the cylindrical channel may be substantially non-overlapping.
US08723416B2 Self-light emitting display unit and electronic device
A self-light emitting display unit capable of improving manufacturing yield is provided. Sizes of color pixel circuits corresponding to pixels for R, G, and B are respectively set unevenly within a pixel circuit according to a magnitude ratio of drive currents which allow color self-light emitting elements in the pixel to emit with a same light emission luminance. Thereby, the pattern densities of color pixel circuits respectively corresponding to the pixels for R, G, and B become even to each other, and the pattern defect rate as the whole pixel circuit is decreased.
US08723412B2 White lighting device
According to the embodiment, a white lighting device includes a semiconductor light-emitting element emitting near-ultraviolet light, and a phosphor layer containing at least a blue-green phosphor emitting blue-green light and a red phosphor emitting red light and emits white light having a correlated color temperature of 5000 K or less and a deviation duv from a blackbody locus of not less than −0.01 nor more than 0.01, in which a ratio of a content of the red phosphor to a content of the blue-green phosphor in the phosphor layer by mass is not less than 35 nor more than 50.
US08723408B2 Diode for a printable composition
An exemplary printable composition of a liquid or gel suspension of diodes comprises a plurality of diodes, a first solvent and/or a viscosity modifier. An exemplary diode comprises: a light emitting or absorbing region having a diameter between about 20 and 30 microns and a height between 2.5 to 7 microns; a plurality of first terminals spaced apart and coupled to the light emitting region peripherally on a first side, each first terminal of the plurality of first terminals having a height between about 0.5 to 2 microns; and one second terminal coupled centrally to a mesa region of the light emitting region on the first side, the second terminal having a height between 1 to 8 microns.
US08723402B2 Structure for an electromagnetic machine having compression and tension members
A structure of an electromagnetic machine includes an outer support member configured to support a conductive winding or a magnet. The structure further includes an inner support member, a first elongate compression member, a second elongate compression member, and an elongate tension member. The first elongate compression member and the second elongate compression member each include a first end portion coupled to the outer support member and a second end portion coupled to the inner support member to resist radial and axial deflection of the outer support member relative inner support member. The elongate tension member includes a first end portion coupled to the first compression member and a second end portion coupled to one of the inner support or the second elongate compression member to resist rotational deflection of the outer support member relative to the inner support member.
US08723393B2 Surface acoustic wave device, electronic apparatus, and sensor apparatus
A SAW device 11 has an IDT which is provided on the principal surface of a quartz crystal substrate 12 having Euler angles (−1.5°≦φ≦1.5°, 117°≦θ≦142°, 42.79°≦|ψ|≦49.57°) and excites a SAW in a stopband upper end mode, and a pair of reflectors which are arranged on both sides of the IDT. Inter-electrode-finger grooves are recessed between the electrode fingers of the IDT, and inter-conductor-strip grooves are recessed between the conductor strips of the reflectors. The wavelength λ of the SAW and the depth G of the inter-electrode-finger grooves satisfy 0.01λ≦G. An IDT line occupancy η and the depth G of the inter-electrode-finger grooves satisfy a predetermined relational expression. The IDT line occupancy η and a reflector line occupancy ηr satisfy the relationship η<ηr. Therefore, an excellent frequency-temperature characteristic and a high Q value in an operation temperature range are realized simultaneously.
US08723388B2 Induction motor, compressor and refrigerating cycle apparatus
The efficiency of an induction motor is improved while suppressing the generation of magnetic flux saturation of a rotor core. In an induction motor, “a magnetic path width of a rotor” which is the product of a circumferential width of a rotor tooth formed in the rotor and the number of rotor teeth is equal to or larger than “a magnetic path width of a stator” which is the product of a circumferential width of a stator tooth formed in the stator and the number of stator teeth.
US08723387B2 Electric wire, coil, device for designing electric wire, and electric motor
An electric wire includes a conductive portion 11 made of a material having a volume resistivity higher than that of copper, wherein the volume resistivity of the conductive portion is specified so that, in a frequency range in which the electric wire is used, a ratio of AC resistance of the conductive portion 11 to AC resistance of reference copper wire is less than 1.
US08723384B2 Rotor of rotary electric machine
A rotary electric machine is provided with a shaft which is a rotary shaft; a laminated core which has a permanent magnet embedded therein and is press-fitted to the shaft; a first member which is a magnetic member and is press-fitted to the shaft so as to hold an end portion of the laminated core; a second member which is a nonmagnetic member and is provided between the end portion of the laminated core and the first member so as to hold an end portion, with respect to the axial direction of the shaft, of the permanent magnet; and at least one of a first gap between the first member and the second member, and a second gap between the laminated core and the second member.
US08723376B2 Mover and linear motor
A mover, in which at each outer surface of a cornered tubular inner yoke, a flat plate magnet magnetized from inside to outside in a direction perpendicular to the outer surface, a flat plate magnet magnetized in an axial direction of the inner yoke, a flat plate magnet magnetized from outside to inside in the direction perpendicular to the outer surface, and a flat plate magnet magnetized in the axial direction of the inner yoke are alternately provided in this order, is passed through an armature in which a first single pole unit and a second single pole unit rotated by 90° with respect to the first single pole unit are alternately stacked, thus forming a linear motor. Windings are collectively wound around core portions of the first single pole unit. Positions of the magnets provided at the outer surfaces of the inner yoke are deviated from each other.
US08723374B2 Non-contact power receiving apparatus
The disclosure provides a non-contact power receiving apparatus including a conductive pattern in a second region of a substrate not covered by a magnetic sheet. The conductive pattern includes first and second electrodes provided in a first plane parallel to a surface of the substrate and arranged in a length direction of the conductive pattern. A third electrode is formed on a second plane parallel with the first plane. A first via hole connects superposed portions of the first and third electrodes to each other, and a second via hole connects superposed portions of the second and third electrodes to each other. As a result, loops of eddy currents generated in the conductive pattern can be made to be small, whereby eddy current loss can be reduced.
US08723373B2 Interface for connecting converter apparatus to two-pole line
The interface has three inputs, a first output which is connected to a first input, a second output which can be connected to a second input or to the third input. The interface also includes a switching device which is connected to the second input, the third input and the second output, and a control device which is coupled to the third input in such a way that a detection signal can be fed from the third input to the control device. The detection signal is indicative of whether the second input or the third input is connected to the second pole of the two-pole line.
US08723370B2 Photovoltaic string sub-combiner
An improved method of collecting DC power in solar photovoltaic systems is disclosed where series string overcurrent protection is provided at distributed series string terminus locations and a tap connection is made to higher current conductors carrying the combined currents of a number of series strings. A number of related string combiner methods and embodiments are disclosed.
US08723368B2 Electrically tunable inductor
An electrically tunable inductor with an equivalent inductance includes a main winding and a tuning winding magnetically coupled to the main winding. The current through the tuning winding is controlled to adjust the equivalent inductance of the electrically tunable inductor. A device may include an electrically tunable inductor. A system may include multiple devices, one or more of the devices including an electrically tunable inductor. A tuning controller within the system may control the current in tuning windings of one or more of the multiple devices in the system. When an electrically tunable inductor is part of a resonant circuit, the resonant frequency may be controlled by adjusting the equivalent inductance of the electrically tunable inductor through controlling the current in the tuning winding. Controlling the current in the tuning winding includes one or more of controlling the peak, direction, frequency, duty cycle, or phase of the current.
US08723365B2 Device for feeding a charge including integrated energy storage
A device for supplying power to a load, requiring both a pre-determined supply of electrical power and high power for short durations of the operating cycle of the load, where the operating cycle is repeated. The power supply device includes a connection to an electrical grid, an AC voltage transformation circuit, a voltage rectification means and a plurality of DC/DC converters mounted in series to terminals of the load. Each of the DC/DC converters has a storage capacitor mounted in parallel to it and at least one of the DC/DC converters is supplied directly by the voltage rectification means. At least another one of the DC/DC converters is not supplied directly by the voltage rectification means. The power supply device may compensate for losses in the power supply device and load, and may substantially continually and uniformly balance voltages at terminals of the storage capacitors.
US08723359B2 Method for controlling sodium-sulfur battery
A plurality of sodium-sulfur batteries are divided into a plurality of groups. Power to be input or output, which is assigned to all sodium-sulfur batteries in order to compensate for fluctuations of output power of a power generation device, is distributed to each group. The plurality of sodium-sulfur batteries divided in the groups are periodically rotated. This enables a uniform utilization rate of the sodium-sulfur batteries to be achieved.
US08723355B2 Autonomously operated buoys with power generation and power usage control
Apparatus, intended to be deployed in a body of water, includes a payload comprised of a multiplicity of different electronic and electromechanical loads and a wave energy converter (WEC) system responsive to the amplitude of waves in the body of water for producing electrical power, which is a function of the wave amplitudes, to power the payload. The apparatus includes switching circuitry for controlling the application of power to selected ones of the loads. Control circuitry and devices which are responsive to the electric power being produced control the switching circuitry for controlling the amount of power supplied to, and consumed by, the loads.
US08723354B2 Electrical power control system for a vehicle
An Electrical Power System for supplying electrical power to the loads of a vehicle comprising a Power Generation Area (11); a Primary Distribution Area (13); a Secondary Distribution Area (15) including Electrical Power Load Management Units (EPLMUs) (17, 17′, 17″, 17′″) that comprise a Control Board (31) and one or more SSPCs (33) for groups of loads (19, 19′, 19″, 19′″); and a master EPLMU (21) that comprise a Control Board (32) and one or more SSPCs (33), powered from the Primary Distribution Area (13) and connected to said EPLMUs (17, 17′, 17″, 17′″) by power supply lines and by a data communication bus (26), and a Load Management Computer (25) connected to said data communication bus (26); said master EPLMU (21) and said Load Management Computer (25) being suitable arranged for full control of the start up and the shutdown of said EPLMUs (17, 17′, 17″, 17′″).
US08723349B2 Apparatus for generating power from a turbine engine
An apparatus for powering an aircraft by generating power from a pressure spool of a turbine engine. AC power can be extracted from the turbine engine by a generator having an integrated autotransformer unit, and converted to DC power.
US08723346B2 Portable integrated power supply and HVAC unit
An integrated portable power unit including a power pack and a generator mounted within a first compartment and including a second isolated air handling compartment. The air handling compartment may include a fan for moving air through ductwork, a radiator for receiving heated cooling water from the power pack and a heat exchanger connected to a compressor for generating cooled water, the compressor and the fan connected to the power pack.
US08723345B2 Portable generator and generating method
A portable generator comprises a fluid pressure generator, a fluid pressure cylinder, a gas power generator, a gas generator, and a charger. The fluid pressure generator is for generating a fluid pressure by pumping, and the fluid pressure generator includes an airbag for compensating a volume change by the pressurized moving of the non-compressible fluid. The fluid pressure cylinder is connected to the fluid pressure generator and comprising a fluid pressure piston, a gas piston, and a piston rod connecting the fluid pressure piston and the gas piston. The gas power generator comprises a high pressure gas chamber, the piston rod, the gas piston of the fluid pressure cylinder, and a cycle path. The gas generator is for generating electricity with a flow of the high pressure gas moving in the high pressure gas chamber as a power source.
US08723344B1 Energy harvesting system
An energy harvesting and harnessing system is mobile and can store energy when the system is not in motion for later use in powering the mobile transport refrigeration unit (TRU) or truck mounted refrigeration units eliminating unnecessary use of the diesel motor on the refrigeration unit. There may be an interface plug between a power generation unit and the cab to power the climate controls and creature comforts in the cab of the truck while parked, thus eliminating unnecessary idling.
US08723341B2 Alignment mark and method of manufacturing the same
An alignment mark includes a plurality of mark units. Each mark unit includes a first element and a plurality of second elements. Each second element includes opposite first and second end portions. The plurality of second elements are arranged along a direction. The first element extends adjacent to the first end portions of the plurality of second elements and parallel to the direction of the plurality of second elements.
US08723334B2 Semiconductor device including semiconductor package
According to one embodiment, a semiconductor device includes a package substrate, a semiconductor package, a first semiconductor chip and a first bonding wire. The package substrate has a first pad on a first principal surface. The semiconductor package is mounted on the first principal surface of the package substrate. The semiconductor package contains a semiconductor chip and has a second pad. The first semiconductor chip is mounted on the semiconductor package. The first bonding wire is connected between the first pad and the second.
US08723333B2 Semiconductor package including multiple chips and separate groups of leads
Provided is a semiconductor package including multiple semiconductor chips, and separate groups of leads connected to the semiconductor chips. The leads are exposed to the outside of the semiconductor package. The plurality of leads may include a first lead group for a first chip group and a second lead group for a second chip group. The first and second chip groups are part of the package.
US08723328B2 Multilayer wiring substrate and method of manufacturing the same
To provide a multilayer wiring substrate in which the connection reliability of via conductors is enhanced, via holes are formed in a resin interlayer insulation layer which isolates a lower conductor layer from an upper conductor layer, and via conductors are formed in the via holes for connecting the lower conductor layer and the upper conductor layer. The surface of the resin interlayer insulation layer is a rough surface, and the via holes open at the rough surface of the resin interlayer insulation layer. Stepped portions are formed in opening verge regions around the via holes such that the stepped portions are recessed from peripheral regions around the opening verge regions. The stepped portions are higher in surface roughness than the peripheral regions.
US08723323B2 Method for fabricating solder columns for a column grid array package
A method for fabricating an electronic device package having a column grid array is disclosed. A column grid array package includes a substrate, an integrated circuit located on a first side of the substrate, and a set of solder columns located on a second side of the substrate. The column grid array package also includes multiple two-tab electronic devices located on the second side of the substrate. The heights of the two-tab electronic devices are substantially identical to the heights of the solder columns.
US08723320B2 Power module and manufacturing method thereof
A power module includes a substrate having a surface on which a plurality of wiring patterns are formed, a semiconductor device mounted on the substrate and electrically connected to a part of the plurality of wiring patterns, and a terminal portion with a lead electrically connected to the other part of the plurality of wiring patterns, and is configured that the lead of the terminal portion is formed by laminating a plurality of metal members which contain a material substantially the same as or softer than the material for forming the other part of wiring patterns, and the material of the plurality of metal members, which is the same as or softer than the material for forming the other part of wiring patterns is electrically connected to the other part of wiring patterns through ultrasonic bonding.
US08723317B2 Trench metal oxide semiconductor field effect transistor with embedded schottky rectifier using reduced masks process
A trench MOSFET with embedded schottky rectifier having at least one anti-punch through implant region using reduced masks process is disclosed for avalanche capability enhancement and cost reduction. The source regions have a higher doping concentration and a greater junction depth along sidewalls of the trenched source-body contacts than along adjacent channel regions near the gate trenches.
US08723316B2 Chip package structure using flexible substrate
A chip package structure includes a flexible substrate having a chip mounting region, a plurality of leads disposed on the flexible substrate, an insulating layer and a chip. Each lead includes a body portion and an inner lead portion connected to each other. The body portion is located outside the chip mounting region and has a thickness greater than that of the inner lead portion. The insulating layer is disposed on the inner lead portions. The chip has an active surface on which a plurality of bumps and a seal ring adjacent to the chip edges are disposed. The chip is mounted within the chip mounting region and electrically connects the flexible substrate by connecting the inner lead portions of the leads with the bumps. The insulating layer is corresponding to the seal ring in position when the chip is electrically connected to the flexible substrate.
US08723312B2 Assembly of a wire element with a microelectronic chip with a groove comprising at least one bump securing the wire element
The assembly comprises at least one microelectronic chip having two parallel main surfaces and lateral surfaces, at least one of the lateral faces comprising a longitudinal groove housing a wire element having an axis parallel to the longitudinal axis of the groove. The groove is delineated by at least two side walls. The wire element is secured to the chip at the level of a clamping area between at least one bump arranged on one of the side walls, and the side wall of the groove opposite said bump. The clamping area has a smaller height than the diameter of the wire element and a free area is arranged laterally to the bump along the longitudinal axis of the groove. The free area has a height, corresponding to the distance separating the two side walls, that is greater than the diameter of the wire element.
US08723308B2 Packages and methods for packaging using a lid having multiple conductive layers
Packaged integrated devices and methods of forming the same are provided. In one embodiment, a packaged integrated device includes a package substrate, a package lid, and an integrated circuit or microelectromechanical systems (MEMS) device. The package lid is mounted to a first surface of the package substrate using an epoxy, and the package lid and the package substrate define a package interior. The package lid includes an interior coating suited to good adhesion with the epoxy, and an exterior coating suited to RF shielding, where the materials of the interior and exterior coatings are different. In one example, the interior lid coating is nickel whereas the exterior lid coating is tin.
US08723304B2 Semiconductor package and methods of fabricating the same
Provided is a semiconductor package having a power device and methods of fabricating the same. The semiconductor package includes a lead frame, a polymer layer component on the lead frame, a metal layer component on the polymer layer component, and a semiconductor chip on the metal layer component. The polymer layer component may include a material formed by adding alumina Al2O3, an aluminum nitride (AlN), or a boron nitride BN to an epoxy resin. The polymer layer component may have high thermal conductivity and good electric insulating characteristics.
US08723302B2 Integrated circuit package system with input/output expansion
An integrated circuit package system includes: forming a base stacking package including: fabricating a base substrate, mounting an integrated circuit on the base substrate, positioning an input/output expansion substrate, having access ports around an inner array area, over the integrated circuit, and injecting a molding compound on the base substrate, the integrated circuit, and the input/output expansion substrate; and mounting a top package on the input/output expansion substrate.
US08723299B2 Method and system for forming a thin semiconductor device
A method and system for forming a thin semiconductor device are disclosed. In one embodiment, a lead frame is provided over a carrier. At least one semiconductor chip is provided on the lead frame and the at least one semiconductor chip is enclosed with an encapsulating material. The thickness of the at least one semiconductor chip and the encapsulating material are reduced. At least one through connection is formed in the encapsulating material and at least one electrical contact element is formed over the at least one semiconductor chip and the at least one through connection.
US08723296B2 Stress compensation for large area gallium nitride or other nitride-based structures on semiconductor substrates
A method includes forming a stress compensating stack over a substrate, where the stress compensating stack has compressive stress on the substrate. The method also includes forming one or more Group III-nitride islands over the substrate, where the one or more Group III-nitride islands have tensile stress on the substrate. The method further includes at least partially counteracting the tensile stress from the one or more Group III-nitride islands using the compressive stress from the stress compensating stack. Forming the stress compensating stack could include forming one or more oxide layers and one or more nitride layers over the substrate. The one or more oxide layers can have compressive stress, the one or more nitride layers can have tensile stress, and the oxide and nitride layers could collectively have compressive stress. Thicknesses of the oxide and nitride layers can be selected to provide the desired amount of stress compensation.
US08723293B1 Compensation network using an on-die compensation inductor
An integrated circuit with an on-die compensation network is presented. The compensation network includes a compensation inductor that has one terminal coupled to a bump pad of the die. Another terminal of the inductor is connected to a metal layer underneath the compensation inductor, forming a pi-configuration with the bump pad. The metal layer routes input and output signals from the integrated circuit. The invention can be used in either flip chip or wire bond applications.
US08723290B2 Electrical fuse device
The invention relates generally to a fuse device of a semiconductor device, and more particularly, to an electrical fuse device of a semiconductor device. Embodiments of the invention provide a fuse device that is capable of reducing programming error caused by non-uniform current densities in a fuse link. In one respect, there is provided an electrical fuse device that includes: an anode; a fuse link coupled to the anode on a first side of the fuse link; a cathode coupled to the fuse link on a second side of the fuse link; a first cathode contact coupled to the cathode; and a first anode contact coupled to the anode, at least one of the first cathode contact and the first anode contact being disposed across a virtual extending surface of the fuse link.
US08723277B2 Tunable MEMS device and method of making a tunable MEMS device
A tunable MEMS device and a method of manufacturing a tunable MEMS device are disclosed. In accordance with an embodiment of the present invention, a semiconductor device comprises a substrate, a moveable electrode and a counter electrode. The moveable electrode or the counter electrode comprises a first region and a second region, wherein the first region is isolated from the second region, wherein the first region is configured to be tuned, wherein the second region is configured to provide a sensing signal or control a system, and wherein the moveable electrode and the counter electrode are mechanically connected to the substrate.
US08723276B2 Semiconductor structure with lamella defined by singulation trench
A method for fabricating a semiconductor structure includes etching a first opening into a substrate; etching a chip singulation trench into the substrate to define a lamella between the first opening and the chip singulation trench; fabricating a sense element for sensing a deflection of the lamella; and singulating the semiconductor structure at the chip singulation trench.
US08723272B2 FinFET device and method of manufacturing same
A semiconductor device and method for fabricating a semiconductor device is disclosed. An exemplary semiconductor device includes a substrate including a fin structure disposed over the substrate. The fin structure includes one or more fins. The semiconductor device further includes an insulation material disposed on the substrate. The semiconductor device further includes a gate structure disposed on a portion of the fin structure and on a portion of the insulation material. The gate structure traverses each fin of the fin structure. The semiconductor device further includes a source and drain feature formed from a material having a continuous and uninterrupted surface area. The source and drain feature includes a surface in a plane that is in direct contact with a surface in a parallel plane of the insulation material, each of the one or more fins of the fin structure, and the gate structure.
US08723269B2 Buried power grid designs for improved radiation hardness in CMOS technologies
Buried power grids are designed as a fine mesh-type pattern of heavily doped diffusion regions with neutral epitaxial region cores to allow the uninterrupted electrical continuity of the epitaxial substrate, thus avoiding floating substrate effects. The buried power grids are formed beneath the epitaxial substrate surface and are powered via electrical contact to adjacent well regions. The buried power grids, when powered, form strongly reverse-biased buried pn junction regions that restrict radiation induced excess charge collection volumes and draw excess charge away from sensitive circuit nodes The method for forming buried power grids requires no uniquely complex process steps and no critical mask alignments to the CMOS devices on the epitaxial top surface. Buried power grids provide enhanced protection to sensitive circuit nodes against logic upsets due to single-particle and prompt dose radiation events and thereby improve the radiation hardness and decreases the latchup susceptibility of CMOS circuits.
US08723264B2 Electrostatic discharge devices and method of making the same
In one embodiment, electrostatic discharge (ESD) devices are disclosed.
US08723261B2 Recessed gate transistor with cylindrical fins
A recessed gate transistor with cylindrical fins is disclosed. The recessed gate transistor is disposed in an active region of a semiconductor substrate. Two isolation regions disposed in the semiconductor substrate to define an active region therebetween. The recessed gate transistor includes a gate structure, a source doping region and a drain doping region. The gate structure has at least three fins forms a concave and convex bottom of the gate structure. The front fin is disposed in one of the two isolation regions, the middle fin is disposed in the active region and a last fin disposed in the other one of the two isolation regions. The front fin and the last fin are both cylindrical. A lower part of the gate structure is M-shaped when view from the source doping region to the drain doping region direction.
US08723258B2 Electrostatic discharge (ESD) tolerance for a lateral double diffusion metal oxide semiconductor (LDMOS) transistor
An ESD tolerance of an LDMOS transistor is improved. An N+ type source layer shaped in a ladder and having a plurality of openings in its center is formed in a surface of a P type base layer using a gate electrode and a resist mask. A P+ type contact layer is formed to be buried in the opening. At that time, a distance from an edge of the opening, that is an edge of the P+ type contact layer, to an edge of the N+ type source layer is set to a predetermined distance. The predetermined distance is equal to a distance at which an HBM+ESD tolerance of the LDMOS transistor, which increases as the distance increases, begins to saturate.
US08723249B2 Non-volatile memory
A non-volatile memory includes a substrate, a gate dielectric layer, a gate conductive layer, a nitride layer, a spacer, a first oxide layer, and a second oxide layer. The gate conductive layer, substrate and gate dielectric layer cooperatively constitute a symmetrical opening thereamong. The nitride layer has an L-shape and formed with a vertical part extending along a sidewall of the gate conductive layer and a horizontal part extending into the opening, wherein the vertical part and the horizontal part are formed as an integral structure and a height of the vertical part is below a top surface of the gate conductive layer. The spacer is disposed on the substrate and the nitride layer. The first oxide layer is disposed among the gate conductive layer, the nitride layer and the gate dielectric layer. The second oxide layer is disposed among the gate dielectric layer, the nitride layer and the substrate.
US08723244B2 Semiconductor device having storage electrode and manufacturing method thereof
A semiconductor device includes a first storage electrode, a second storage electrode, a first landing pad, a capacitive insulating film, and a plate electrode. The second storage electrode is arranged above the first storage electrode. The first landing pad is arranged between a top surface of the first storage electrode and a bottom surface of the second storage electrode. The first landing pad connects the first storage electrode and the second storage electrode. The first landing pad has a first landing surface larger than the bottom surface of the second storage electrode. The second storage electrode is placed on the first landing surface. The capacitive insulating film is laminated on the first and second storage electrodes and on an outer circumferential surface of the first landing pad. The plate electrode contacts the capacitive insulating film.
US08723237B2 Method for designing a semiconductor device including stress films
A method for designing a semiconductor device includes arranging at least a pattern of a first active region in which a first transistor is formed and a pattern of a second active region in which a second transistor is formed; arranging at least a pattern of a gate wire which intersects the first active region and the second active region; extracting at least a first region in which the first active region and the gate wire are overlapped with each other; arranging at least one pattern of a compressive stress film on a region including the first active region; and obtaining by a computer a layout pattern of the semiconductor device, when the at least one pattern of the compressive stress film is arranged, end portions of the at least one pattern thereof are positioned based on positions of end portions of the first region.
US08723234B2 Semiconductor device having a diode forming area formed between a field-effect transistor forming area and a source electrode bus wiring or pad
A semiconductor device of an embodiment includes: a semiconductor substrate; a field-effect transistor formed on the semiconductor substrate; and a diode forming area which is adjacent to a forming area of the field-effect transistor, wherein the diode forming area is insulated from the forming area of the transistor on the semiconductor substrate, and includes a first diode electrode in which a gate electrode of the field-effect transistor is placed in Schottky barrier junction and/or ohmic contact with the semiconductor substrate through a bus wiring or a pad; and a second diode electrode in which a source electrode of the field-effect transistor is placed in ohmic contact and/or Schottky barrier junction with the semiconductor substrate through a bus interconnection or a pad to form a diode between the gate electrode and the source electrode.
US08723233B2 CMOS with channel P-FinFET and channel N-FinFET having different crystalline orientations and parallel fins
An integrated circuit includes at least one single-crystal fin having a first crystal orientation. The integrated circuit also includes at least one single-crystal fin having a second crystal orientation. The single-crystal fin having the first crystal orientation and the single-crystal fin having the second crystal orientation are substantially parallel.
US08723230B2 Semiconductor device
Disclosed is a semiconductor device including transistors B on an output side of a current mirror, arranged uniformly in a surrounding area of a transistor A on an input side of the current mirror. The transistors B are arranged at equal distances, adjacently to the transistor A, on both sides of the transistor A.
US08723228B1 Power semiconductor device
A power semiconductor device is disclosed. The power semiconductor device includes a substrate, a first semiconductor layer disposed on the substrate, a second semiconductor layer disposed on the first semiconductor layer, a third semiconductor layer disposed on the second semiconductor layer and exposing a portion of the second semiconductor layer, a gate electrode disposed on the portion of the second semiconductor layer exposed via the third semiconductor layer, and a source electrode and a drain electrode disposed on the third semiconductor layer at both sides of the gate electrode to be spaced apart from each other. An electrical segregation region is formed in the third semiconductor layer between the gate electrode and the drain electrode.
US08723225B2 Guard rings on fin structures
A device includes a semiconductor substrate, isolation regions extending into the semiconductor substrate, a plurality of semiconductor fins higher than top surfaces of the isolation regions, and a plurality of gate stacks. Each of the gate stacks includes a gate dielectric on a top surface and sidewalls of one of the plurality of semiconductor fin, and a gate electrode over the gate dielectric. The device further includes a plurality of semiconductor regions, each disposed between and contacting two neighboring ones of the plurality of semiconductor fins. The device further includes a plurality of contact plugs, each overlying and electrically coupled to one of the plurality of semiconductor regions. An electrical connection electrically interconnects the plurality of semiconductor regions and the gate electrodes of the plurality of gate stacks.
US08723216B2 Method of tuning work function of metal nanostructure-based transparent conductor
The present disclosure relates to methods for tuning the work function of a metal nanostructure-based conductive film by forming a dipole surface layer on individual metal nanostructures.
US08723212B2 Semiconductor light source
A semiconductor light source for illuminating physical spaces includes a lead frame with multiple facets, each facet having one or more semiconductor light emitting devices mounted thereon.
US08723210B2 Light emitting device and light emitting device package having the same
Disclosed are a light emitting device. The light emitting device includes a light emitting structure including a first and second conductive semiconductors, and an active layer; an insulating layer on a lateral surface of the light emitting structure; an electrode on the first conductive semiconductor layer; an electrode layer under the second conductive semiconductor layer; and a protective layer including a first portion between the light emitting structure and the electrode layer and a second portion extending outward beyond a lower surface of the light emitting structure, wherein the first conductive semiconductor layer includes a first top surface including a roughness on a first region, and a second top surface lower than the first region and being closer the lateral surface of the light emitting structure than the first region, wherein the second top surface is disposed on an edge portion of the first conductive semiconductor layer.
US08723204B2 Polymeric wavelength converting elements
A wavelength converting element (104), typically for a LED (101), is provided, comprising luminescent particles (105) dispersed in a matrix (106) comprising crosslinked polysiloxane. Crosslinked polysiloxanes are temperature stable, typically up to temperatures above 300° C., meaning that they are stable under normal operating conditions of light emitting diodes. Further, crosslinked polysiloxanes are stable towards exposure to light, meaning that they will not degrade/discolor as a consequence of high intensity light exposure. The polymeric wavelength converter can easily be shaped in different forms. This may lead to better outcoupling of the light from a LED-converter system.
US08723203B2 Light emitting device, electrode structure, light emitting device package, and lighting system
Provided are a light emitting device, an electrode structure, a light emitting device package, and a lighting system. The light emitting device includes a conductive layer, an electrode, a light emitting structure layer disposed between the electrode and the conductive layer and comprising a first semiconductor layer, a second semiconductor layer, and an active layer between the first semiconductor layer and the second semiconductor layer, and a light guide layer between the first semiconductor layer and the electrode.
US08723202B2 Semiconductor light emitting device having roughness layer
A semiconductor light emitting device includes a substrate, a first conductive semiconductor layer, an active layer on the first conductive semiconductor layer, a second conductive semiconductor layer on the active layer, and a roughness layer on the second conductive semiconductor layer. The second conductive semiconductor layer includes a shape of multiple horns, and the roughness layer includes a shape of multiple horns. The second conductive semiconductor layer includes a roughness in which horn shapes and inverse-horn-shaped shapes are alternately formed, and the roughness has a height of about 0.5 μm to about 1.2 μm and a diameter of about 0.3 μm to about 1.0 μm.
US08723201B2 Light-emitting devices with substrate coated with optically denser material
A light-emitting device includes a transparent substrate with a light emitting structure formed on one side of the substrate and a transparent layer formed on the opposing side of the substrate. The refractive index of the transparent layer is greater than the refractive index of the substrate. A light-emitting device includes a package cup having a reflective sidewall and a light emission surface and a light emitting diode (LED) embedded in the package cup. The LED comprises a transparent substrate and a transparent layer formed on the substrate. The reflective sidewall has a first portion in a central area of the package cup and a second portion in a peripheral area of the package cup, the first portion reflects light emitted from the transparent layer to the second portion and, then, the second portion further reflects the light received from the first portion to the light emission surface of the package cup.
US08723198B2 Wavelength-converting converter material, light-emitting optical component, and method for the production thereof
Disclosed is a wavelength-converting converter material comprising at least one wavelength-converting phosphor comprising phosphor particles, wherein a portion of said phosphor or all of said phosphor is present in the form of nanoparticles. Also disclosed is a light-emitting optical component comprising such a converter material and a method for producing such components.
US08723197B2 Nitride semiconductor light emitting device and method of manufacturing the same
A semiconductor light emitting device including a first semiconductor layer, an active layer formed on the first semiconductor layer, a second semiconductor layer formed on the active layer, and at least one SiNx cluster layer formed between the first semiconductor layer and the second semiconductor layer.
US08723196B2 Light emitting device
Light-emitting elements have a problem that their light-extraction efficiency is low due to scattered light or reflected light inside the light-emitting elements. The light-extraction efficiency of the light-emitting elements needs to be enhanced by a new method. According to the present invention, a light-emitting element includes a first layer generating holes, a second layer including a light-emitting layer for each emission color and a third layer generating electrons between an anode and a cathode, and the thickness of the first layer is different depending on each layer including the light-emitting layer for each emission color. A layer in which an organic compound and a metal oxide are mixed is used as the first layer, and thus, the driving voltage is not increased even when the thickness is increased, which is preferable.
US08723193B2 Multi-layer wiring substrate, active matrix substrate, image display apparatus using the same, and multi-layer wiring substrate manufacturing method
A multiple-layer wiring substrate having a first conductive layer; an interlayer insulating layer; and a second conductive layer is disclosed, wherein the interlayer insulating layer includes a material whose surface energy is changed by receiving energy, and has a first region which does not include a contact hole and a second region which is formed such that its surface energy is higher than that of the first region, wherein a region within the contact hole of the first conductive layer has surface energy which is higher than surface energy of the second region of the interlayer insulating layer, and wherein the second conductive layer is formed by laminating, wherein the second conductive layer is in contact with the second region of the interlayer insulating layer along the second region, and is connected to the first conductive layer via the contact hole.
US08723192B2 Method for producing an optoelectronic semiconductor component and optoelectronic semiconductor component
A method for producing an optoelectronic semiconductor component includes providing a carrier; arranging at least one optoelectronic semiconductor chip at a top side of the carrier; shaping a shaped body around the at least one optoelectronic semiconductor chip, wherein the shaped body covers all side areas of the at least one optoelectronic semiconductor chip, and wherein a surface facing away from the carrier at the top side and/or a surface facing the carrier at the underside of the at least one semiconductor chip remains substantially free of the shaped body or is exposed, and removing the carrier.
US08723191B2 Electronic device which performs as light emitting diode and solar cell
An electronic device performing as a light emitting diode and a solar cell, and which comprises: a solar cell unit including a first electrode layer, an energy-level compensation layer formed on the first electrode layer, a photoelectric-conversion layer formed on the energy level compensation layer, and a shared electrode layer formed on the photoelectric-conversion layer; and a light emitting diode unit including the shared electrode layer, and a light emitting layer formed on the shared electrode layer and a second electrode layer formed on the light emitting layer, wherein a LUMO energy-level of the energy-level compensation layer is smaller than a work function of the first electrode layer and is larger than a LUMO energy level of the photoelectric-conversion layer, thereby increasing the generating efficiency of the solar cell unit or the luminous efficiency of the light emitting diode unit due to high electron mobility among the respective layers.
US08723190B2 Light emitting device having a patterned conductive layer with at least a passivated side surface
A light emitting device is provided. A light emitting device that includes a substrate, a first electrode, a passivation layer, a second electrode, and a light emitting layer is provided. The first electrode is disposed on the substrate and includes a first patterned conductive layer. The first patterned conductive layer includes an alloy containing a first metal and a second metal. The passivation layer is at least disposed on a side surface of the first electrode and includes a compound of the second metal. Here, a work function of the compound of the second metal ranges from about 4.8 to about 5.5. The second electrode is disposed on the first electrode. The light emitting layer is disposed between the first electrode and the second electrode.
US08723186B2 Ionic junction for radiation detectors
Radiation detector. The detector includes an ionic junction having an ionically bonded wide band gap material having a first region dominated by positively charged ionic defects in intimate contact with a second region dominated by negatively charged ionic defects forming depleted regions on both sides of the junction resulting in a built-in electric field. The detector also includes an ionic junction having a first ionically bonded wide band gap material dominated by positively charged ionic defects in intimate contact with a second ionically bonded wide band gap material dominated by negatively charged ionic defects forming depleted regions on both sides of the junction resulting in a built-in electric field. Circuit means are provided to establish a voltage across the junction so that radiation impinging upon the junction will cause a current to flow in the circuit.
US08723184B2 Semiconducting sheet
A substrate-free semiconducting sheet has an array of semiconducting elements dispersed in a matrix material. The matrix material is bonded to the edge surfaces of the semiconducting elements and the substrate-free semiconducting sheet is substantially the same thickness as the semiconducting elements.
US08723182B2 Semiconductor device and method of manufacturing the same
A semiconductor device includes TFTs designed in accordance with characteristics of circuits. In a first structure of the invention, the TFT is formed by using a crystalline silicon film made of a unique crystal structure body. The crystal structure body has a structure in which rod-like or flattened rod-like crystals grow in a direction parallel to each other. In a second structure of the invention, growth distances of lateral growth regions are made different from each other in accordance with channel lengths, of the TFTs. By this, characteristics of TFTs formed in one lateral growth region can be made as uniform as possible.
US08723181B2 Stacked transistors and electronic devices including the same
Stacked transistors and electronic devices including the stacked transistors. An electronic device includes a substrate, a first transistor on the substrate and including a first active layer, a first gate, and a first gate insulating layer between the first active layer and the first gate, a first metal line spaced apart from the first gate on the substrate, a first insulating layer covering the first transistor and the first metal line, and a second transistor on the first insulating layer between the first transistor and the first metal line, and including a second active layer, a second gate, and a second gate insulating layer between the second active layer and the second gate.
US08723177B2 Electrical test structure for devices employing high-k dielectrics or metal gates
Disclosed herein are various electrical test structures for evaluating semiconductor devices that employ high-k dielectrics and/or metal gate electrode structures. In one example, the test structure disclosed herein includes a first line formed over an isolation material, a first active region defined in a semiconducting substrate and a first extension formed over an isolation material, the first extension extending from a first side of the first line, wherein the first extension is positioned proximate the first active region and wherein the first line and the first extension are comprised of at least one of a high-k layer of insulating material or a metal layer.
US08723175B2 Oxide semiconductor field effect transistor and method for manufacturing the same
A field effect transistor including a semiconductor layer including a composite oxide which contains In, Zn, and one or more elements X selected from the group consisting of Zr, Hf, Ge, Si, Ti, Mn, W, Mo, V, Cu, Ni, Co, Fe, Cr, Nb, Al, B, Sc, Y and lanthanoids in the following atomic ratios (1) to (3): In/(In+Zn)=0.2 to 0.8  (1) In/(In+X)=0.29 to 0.99  (2) Zn/(X+Zn)=0.29 to 0.99  (3).
US08723172B2 Display device, thin film transistor array substrate and thin film transistor having oxide semiconductor
A display device including a thin film transistor array substrate, transparent electrode substrate and a display medium layer disposed therebetween is provided. The thin film transistor array substrate includes a plurality of thin film transistors with an oxide semiconductor layer respectively. In each thin film transistor, a gate electrode and a gate insulating layer are disposed on a substrate sequentially and the gate electrode is covered by the gate insulating layer. The oxide semiconductor layer is conformably covering on the gate insulating layer and has a channel region located above the gate electrode. A source electrode and a drain electrode of each thin film transistor are disposed on the oxide semiconductor layer and at one side of the channel region respectively. Since the oxide semiconductor layer is made of transparent material, the patterning process of the oxide semiconductor layer can be omitted during the manufacturing process of the reflective display device. Thus, the cost and time-consumed of manufacturing process of the reflective display device can be reduced.
US08723167B2 Reflecting material and light emitting diode device
A reflecting material contains a silicone resin composition prepared from a polysiloxane containing silanol groups at both ends, an ethylenic silicon compound, a silicon compound containing an epoxy group, an organohydrogenpolysiloxane, a condensation catalyst, and an addition catalyst; and a light reflecting component.
US08723164B2 Electronic device
An electronic device comprising a substrate, a first electrode, at least one organic functional layer, and a second electrode is indicated. The organic functional layer comprises a first, a second, and a third matrix material, wherein the first matrix material has a larger band gap than the second and the third matrix materials.
US08723161B1 Two-color infrared detector
A two-color detector includes a first absorber layer. The first absorber layer exhibits a first valence band energy characterized by a first valence band energy function. A barrier layer adjoins the first absorber layer at a first interface. The barrier layer exhibits a second valence band energy characterized by a second valence band energy function. The barrier layer also adjoins a second absorber layer at a second interface. The second absorber layer exhibits a third valence band energy characterized by a third valence band energy function. The first and second valence band energy functions are substantially functionally or physically continuous at the first interface and the second and third valence band energy functions are substantially functionally or physically continuous at the second interface.
US08723157B2 Non-volatile semiconductor storage device and method of manufacturing the same
A non-volatile semiconductor storage device includes memory cells, each of which is arranged at an intersection between a first wiring and a second wiring intersecting each other. Each of the memory cells includes: a first electrode layer; a plurality of variable resistance layers laminated on the first electrode layer and functioning as variable resistance elements; a second electrode layer formed between the variable resistance layers; and a third electrode layer formed on the top one of the variable resistance layers. Each of the variable resistance layers is composed of a material containing carbon.
US08723154B2 Integration of an amorphous silicon resistive switching device
An integrated circuit device. The integrated circuit device includes a semiconductor substrate having a surface region. A gate dielectric layer overlies the surface region of the substrate. The device includes a MOS device having a p+ active region. The p+ active region forms a first electrode for a resistive switching device. The resistive switching device includes an amorphous silicon switching material overlying the p+ active region and a metal electrode overlies the first metal conductor structure. The metal electrode includes a metal material, upon application of a positive bias to the metal electrode, forms a metal region in the amorphous silicon switching material. The MOS device provides for a select transistor for the integrated circuit device.
US08723151B2 Front to back resistive random access memory cells
A resistive random access memory cell formed in an integrated circuit includes a first resistive random access memory device including an anode and a cathode, a second resistive random access memory device including an anode and a cathode, the cathode of the second resistive random access memory device connected to the anode of the first resistive random access memory device, a programming transistor having a first source/drain terminal connected to a programming potential node, a second source/drain terminal connected to the anode of the first resistive random access memory device and the cathode of the second resistive random access memory device, and a gate connected to a program-enable nod, and at least one switch transistor having a gate connected to the anode of the first resistive random access memory device and the cathode of the second resistive random access memory device.
US08723150B2 Semiconductor memory device having a reversibly variable resistance layer
A semiconductor memory device according to an embodiment comprises a semiconductor layer, a variable resistance layer, a sidewall layer, and a buried layer. The semiconductor layer functions as a rectifying device. The variable resistance layer is provided above or below the semiconductor layer and reversibly changes its resistance. The sidewall layer is in contact with a sidewall of the semiconductor layer. The buried layer is embedded in the sidewall layer and is made of material different from that of the sidewall layer. These configurations may adjust the electrical characteristics of the rectifying device to any value.
US08723148B2 Safety net system
A safety net system for blocking electromagnetic field (EMF) exposure from electronic devices is provided. The safety net system comprises a hair net for covering at least a portion of a head and a body net having a back portion for covering an upper back and shoulders, a first front portion for covering a right breast, and a second front portion covering a left breast. A first anti-EMF chip is mounted to the hair net, a second anti-EMF chip is mounted to the back portion, a third anti-EMF chip is mounted to the first front portion, and a fourth anti-EMF chip mounted to the second front portion. Upon positioning the hair net over the at least a portion of the head and upon draping the body net over the shoulders thereby covering the upper back and breasts, the anti-EMF chips block and shield EMF radiation from reaching the body part.
US08723142B2 Light source device and projector
A light source device includes: a light emitting plate that has a plurality of segment regions including a transmissive portion that transmits light and a reflective portion on which a fluorescent substance layer; a light source that irradiates the fluorescent substance layer of the light emitting plate with the excitation light; a dichroic mirror that is disposed between the light source and the light emitting plate to transmit the excitation light and reflect fluorescent light from fluorescent substances of the fluorescent substance layer; and an optical device that condenses the excitation light transmitted by the transmissive portion of the light emitting plate and the fluorescent light reflected by the dichroic mirror on a single optical path to form a condensed light and radiate the condensed light toward the same direction.
US08723141B2 Line sensor unit and automatic transaction apparatus
A line sensor unit includes: a first light source configured to emit excitation light that excites a fluorescent substance; a second light source configured to emit non-excitation light that does not excite the fluorescent substance; a line sensor configured to receive light from a medium obtained by irradiating the medium with the excitation light or the non-excitation light; a light-emitting unit, which is excited upon receipt of the excitation light, configured to emit light responsive to the excitation light, the emitted light being incident on the line sensor; and a light-shielding unit, which is provided on a side opposite to a line-sensor side of the light-emitting unit, configured to block light advancing from the light-emitting unit to the medium.
US08723139B2 System and method for automatically determining optimal excitation and emission wavelengths of a fluorophore
A system for performing spectrofluorometry of a fluorophore sample is provided. The system includes an input module that receives user input corresponding to spectrofluorometer settings. A control module transmits control signals for controlling the spectrofluorometer during respective wavelength scans of a fluorophore sample and a blank sample. The control signals provide for automatic execution of the wavelength scans over an excitation wavelength range and an emission wavelength range. A signal-to-background determination module automatically determines multiple signal-to-background ratios based on fluorescence measurements of the fluorophore sample and the blank sample received from the spectrofluorometer. A signal-to-background analysis module automatically determines the maximum signal-to-background ratio from the multiple signal-to-background ratios.
US08723138B2 Electron beam source and method of manufacturing the same
A tip of an electron beam source includes a core carrying a coating. The coating is formed from a material having a greater electrical conductivity than a material forming the surface of the core.
US08723136B2 Particle beam system and method for operating the same
A method of operating a particle beam system includes determining a deflection amount and a deflection time of a beam deflection module connected to a data network. The method also includes determining an un-blank time of a beam blanking module connected to the data network, and determining a blank time of the beam blanking module connected to the data network. The method further includes generating a data structure which includes plural data records, wherein each data record includes a command representing an instruction for at least one of the modules, and a command time representing a time at which the instruction is to be sent to the data network. In addition, the method includes sorting the records of the data structure by command time, and generating a set of digital commands based on the data structure. Moreover, the method includes sending the digital commands of the set to the network in an order corresponding to an order of the sorted records.
US08723135B2 Ion beam bending magnet for a ribbon-shaped ion beam
An ion beam bending magnet provides a curved path through the magnet for bending a ribbon-shaped ion beam having its major cross-sectional dimension normal to the bending plane of the magnet. The magnet comprises a ferromagnetic yoke surrounding the beam path and having an internal profile in cross-section formed of four angled sides. These sides are angled to the major dimension of the ribbon beam passing through the magnet, so that the internal profile of the yoke is relatively wide in the center of the ribbon beam and relatively narrow near the top and bottom edges of the ribbon beam. Electrical conductors against the internal surfaces of the yoke provide a uniform distribution of electrical current per unit length along the angled sides of the profile, providing a substantially uniform magnetic bending field within the magnet yoke.
US08723132B2 Single photon radiation detector
The invention relates to a radiation detector that is particularly suited for energy resolved single X-ray photon detection in a CT scanner. In a preferred embodiment, the detector has an array of scintillator elements in which incident X-ray photons are converted into bursts of optical photons. Pixels associated to the scintillator elements determine the numbers of optical photons they receive within predetermined acquisition intervals. These numbers can then be digitally processed to detect single X-ray photons and to determine their energy. The pixels may particularly be realized by avalanche photodiodes with associated digital electronic circuits for data processing.
US08723127B2 Radiation detector
A radiation detector of a compact size and producing almost no image defect is disclosed, comprising a first radiation-transmissive substrate, a first adhesive layer, a second radiation-transmissive substrate, a scintillator layer and an output substrate provided with a photoelectric conversion element layer which are provided sequentially in this order, wherein an arrangement region of the scintillator layer in a planar direction of the layer includes an arrangement region of the photoelectric conversion element layer in a planar direction of the layer and an arrangement region of the first substrate in a planar direction of the substrate, and the arrangement region of the first substrate includes the arrangement region of the photoelectric conversion element layer; and when the arrangement region of the scintillator layer is divided to plural areas, a coefficient of variation of filling factor is 20% or less which is defined as a standard deviation of filling factor of phosphor of the plural areas, divided by an average value of the filling factor.
US08723115B2 Method and apparatus for detecting buried defects
One embodiment relates to a method of detecting a buried defect in a target microscopic metal feature. An imaging apparatus is configured to impinge charged particles with a landing energy such that the charged particles, on average, reach a depth within the target microscopic metal feature. In addition, the imaging apparatus is configured to filter out secondary electrons and detect backscattered electrons. The imaging apparatus is then operated to collect the backscattered electrons emitted from the target microscopic metal feature due to impingement of the charged particles. A backscattered electron (BSE) image of the target microscopic metal feature is compared with the BSE image of a reference microscopic metal feature to detect and classify the buried defect. Other embodiments, aspects and features are also disclosed.
US08723110B2 Atmospheric pressure ion source for mass spectrometry
An apparatus for generating ions includes an Electrospray ionization source configured to provide a spray of charged droplets from a sample solution during operation of the apparatus; an atmospheric pressure chemical ionization (APCI) source including a corona discharge needle configured to produce a corona discharge that further ionizes the spray during operation of the apparatus; and a gas delivery system configured to deliver a gas flow to the corona discharge needle during operation of the apparatus, wherein the gas flow comprises a reagent ion gas which facilitates ionization of the spray by the corona discharge.
US08723108B1 Transient level data acquisition and peak correction for time-of-flight mass spectrometry
Methods, apparatus and systems for acquiring spectrometric data from analyte ions implement transient-level data acquisition and peak correction in a time-of-flight mass spectrometer. Transient spectra including analyte peaks and reference mass peaks are recorded, from which a set of averaged peak centroids of the reference masses is generated. The peaks of reference masses in each transient spectrum are compared to the averaged peak centroids. From this comparison, an appropriate correction function is applied to each transient spectrum to correct the positions of the analyte peaks in each transient spectrum. The corrected transient spectra are then summed to obtain a corrected averaged spectrum.
US08723103B2 Optical encoder readhead configured to block stray light with dummy vias
An optical readhead for measuring a displacement along a measuring axis direction between the readhead and a scale track comprises an illumination portion configured to output source light to the scale track and a monolithic detector configuration. The monolithic detector configuration comprises: a first track photodetector portion configured to receive scale light from the scale track; a first metal layer; a second metal layer; and a plurality of dummy vias between the first metal layer and the second metal layer. The plurality of dummy vias is arranged to block light transmission along a layer between the first and second metal layers, and the plurality of dummy vias is formed by the same process steps used to fabricate a plurality of active vias used to connect circuit elements on the monolithic detector configuration.
US08723099B2 Solid-state imaging apparatus
An imaging apparatus includes a plurality of unit pixels arranged in a matrix and configured to generate a signal by photoelectric conversion, a plurality of pixel output lines connected to each column of the unit pixels, a plurality of column amplifiers configured to amplify a signal of the pixel output lines, and a driving circuit configured to generate a control signal of the column amplifiers. Each of the column amplifiers includes first and second input terminals, an output terminal, an input capacitance between the first and second input terminals, and a first switch between the second input and output terminals. The driving circuit is configured to generate the control signal so as to make a period for switching the first switch from a conductive state to a non-conductive state longer than a period for switching the first switch from the non-conductive state to the conductive state.
US08723098B2 Charge coupled image sensor and method of operating with transferring operation of charge packets from plural photodetectors to vertical CCD shift registers (as amended)
A CCD image sensor includes vertical CCD shift registers and gate electrodes disposed over the vertical CCD shift registers. The gate electrodes are divided into distinct groups of gate electrodes. The CCD image sensor is adapted to operate in an accumulation mode and a charge transfer mode, an accumulation mode and a charge shifting mode, or an accumulation mode, a charge transfer mode, and a charge shifting mode. The charge transfer mode has an initial charge transfer phase and a final charge transfer phase. The charge shifting mode has an initial charge shifting phase and a final charge shifting phase.
US08723093B2 Image sensors and methods with shared control lines
An image sensor includes a pixel array with a plurality of pixels. Two or more rows of pixels in the pixel array share a control line in the pixel array, and pixels of the two or more rows of pixels that are in a same column of the pixel array are connected to provide output to different column readout lines. A method includes providing a control signal over a control line within a pixel array to pixels in two or more rows of the pixel array, and reading out signals from the pixels in the two or more rows at a same time over different column readout lines. An image sensor includes a pixel array with a plurality of pixels, and two or more columns of pixels in the pixel array may share a control line in the pixel array for receiving a control signal.
US08723090B2 Microwave field director structure having vanes covered with a conductive sheath
A reusable self-supporting field director useful for heating an article in a microwave oven is characterized by a plurality of vanes, each vane extending radially outwardly from a central axis and being angularly adjacent to two other vanes. The vanes are attached to each other at their inner ends. Each vane has a substrate formed from an electrically non-conductive material, and an electrically conductive sheath encasing the substrate so that a portion of the first and second major surfaces are covered by an electrically conductive material. The sheath is arranged on the substrate in a laterally symmetric fashion so that thermal expansion effects due to heating are equalized across the thickness of each vane.
US08723088B2 System and method for induction heating a helical rotor using a coil
Embodiments of the invention provide a system and method for induction heating a helical rotor of a progressing cavity pump in order to reduce the surface roughness of the rotor. In order to heat the rotor most evenly, it is desired to space the coil as closely around the rotor as possible. The invention provides a mechanism for threading the helical rotor through an induction coil having an interior diameter which is less than the major diameter of the rotor. The induction coil may include one loop and overlapping ends. The rotor to be heated is rotated about its longitudinal axis and advanced axially through the coil as it rotates. The axial speed and rotational speed are synchronized so that the rotor moves one pitch through the coil for each complete rotation.
US08723087B2 Method for manufacturing pipe-type woven carbon fibers and carbon fiber heating lamp using the pipe-type woven carbon fibers
A method of manufacturing a carbon-fiber pipe which is hollow and has a net shape, by knitting carbon fibers and general fibers, applying carbon or ceramic, and heating to burn the general fibers, and a carbon fiber heating lamp using the carbon-fiber pipe are provided. The carbon fiber heating lamp includes a vacuum glass tube, a tubular carbon fiber pipe, which is knitted using carbon fiber and general fiber as a raw material and has a hollow part, and a heating element. The heating element includes the tubular carbon fiber pipe which has a predetermined length and is installed in the vacuum glass tube, and generates heat using power supplied from an exterior through both terminals provided on an outer portion of the vacuum glass tube.
US08723085B2 Temperature controlled/limiting heating element for an electric cooking appliance
A temperature controlled/limiting heating element for an electrically powered cooking appliance, having: a plate with an upper contact heating surface; a pair of heating element terminals adapted for removably engaging electrical power supply terminals of the electrically powered cooking appliance; a plurality of resistive heating wires, in thermal engagement with a lower surface of the top plate, comprising: a non-cycling resistive heating wire connected in series to the heating element terminals; and a cycling resistive heating wire connected in series to the heating element terminals via a thermostat switch in thermal engagement with a lower surface of the top plate, wherein the thermostat switch is normally closed when exposed to a sensed temperature below a set temperature and the thermostat switch opens when the sensed temperature is equal to or exceeds the set temperature.
US08723078B2 Monitoring of a welding process
A method of monitoring a welding process, comprising detecting a selected portion of a light spectrum of plasma plume of a fusion welding process with a photo detector, processing the detected portion of the spectrum, comparing the detected portion of the spectrum with an expected spectra to determine whether a weld is acceptable, providing a signal to a welder control, and adjusting the weld process based on the signal.
US08723070B2 Power switchgear
A power switchgear according to the present invention includes a pass-through hole which is formed in a fixed side contact case that is supported by a fixed side insulation supporter to fix and retain the fixed side of a vacuum valve and has a larger inner diameter than an outer diameter of the vacuum valve so that the vacuum valve is capable of horizontally passing through and the fixed side end portion of the vacuum valve is placed by passing through; and a fixed side connection conductor attached to the fixed side contact case and connected to the fixed side end portion of the vacuum valve.
US08723069B2 Viewing window and ground contact connection for a high-voltage arrangement
A high-voltage arrangement has at least one switching device, a housing and a drive for the switching device. The housing is formed with a first housing opening and a second housing opening. Both the first and second housing openings are suitable for the selective fitting of a viewing window or a ground contact connection.
US08723068B2 Method and system for optically inspecting manufactured rounds of ammunition or cylindrical components of the rounds to obtain rounds which exhibit superior accuracy when fired
A method and system for optically inspecting manufactured rounds of ammunition or cylindrical components of the rounds to obtain rounds which exhibit superior accuracy when fired are provided. The method includes providing a nominal numerical value and an acceptable range of numerical values for a size or a geometric characteristic of an acceptable manufactured round of ammunition or a cylindrical component of the round for a predetermined caliber of ammunition. Also provided is a high-performance range of numerical values for the corresponding size or geometric characteristic of a high-performance manufactured round of ammunition or a cylindrical component of the high-performance round for the predetermined caliber of ammunition. A generated signal identifies the inspected round or a round including the inspected cylindrical component as having superior accuracy when fired relative to acceptable inspected rounds or inspected cylindrical components having a corresponding measured value which is outside the high-performance range but within the acceptable range of numerical values.
US08723067B2 Capacitive touch control sensor
A capacitive touch control sensor includes a plurality of first electrodes, a plurality of first electrode wires, a plurality of second electrodes, a plurality of second electrode wires. The first and second electrodes are disposed at predetermined interval. The first electrodes have two opposite sensor units and a connecting unit which bridges there-between. Each of the first electrode wires connects one of the first electrodes. Each of the second electrode wires connects more than one of the second electrodes in a same column. The first and second electrodes are arranged alternatively and the neighboring second electrodes are disposed respectively at either side of the connecting unit of the first electrodes.
US08723064B2 Button mechanism and electronic device thereof
A button mechanism includes a casing. A lock hole and an engaging portion are formed and disposed on a bottom of the casing, and a plurality of open slots is formed on a lateral wall of the casing. The button mechanism further includes a plurality of buttons respectively disposed on the corresponding open slots, a fixing component, and a supporting component. An end of the supporting component is engaged with the engaging portion. The supporting component includes a first part whereon a piercing hole is formed. The fixing component pierces through the piercing hole and the lock hole to fix the first part on the bottom of the casing. The supporting component further includes a second part connected to the first part and contacting against the plurality of first buttons for constraining movements of the plurality of buttons relative to the casing.
US08723061B2 MEMS switch and communication device using the same
A MEMS switch in which contact force sufficient to make a contact having low contact resistance is maintained after contact-formation to maintain low contact resistance at the contact where the signal is transmitted in an “on” state. The MEMS switch includes a first electrode, a second electrode opposed to and separated from the first electrode, a third and a fourth electrodes, wherein electrical contact is made between the electrodes by electrostatic force generated between the electrodes, and a bump which can form the contact between the electrodes is provided on an electrode, and a gap is formed between the electrodes when the electrical contact is made between the electrodes.
US08723060B2 Method and mechanism for power tool lock-off
Embodiments of the present invention disclosed herein present forms of a method and mechanism for a power tool lock-off, wherein accidental activation of the power tool may be inhibited. Pressing a lock-off release button on the tool housing induces a locking member to move from a first position to a second position, allowing a trigger to access a power switch within the housing. Various forms and methods of lock-off mechanisms are enabled.
US08723058B2 Mounting apparatus and electronic device enclosure with the same
A mounting apparatus is secured to a front wall of an enclosure. A door is rotatably attached to the front wall. The front wall includes a first securing portion and a second securing portion. The mounting apparatus includes a sliding rail for being attached to the front wall and a mounting member slidably attached to the sliding rail. The mounting member includes a mounting portion for engaged with the first securing portion or the second securing portion. When the mounting portion is engaged with the first securing portion, the mounting member is engaged with the door, for preventing the door from rotating relative to the front wall; and when the mounting portion is engaged with the second securing portion, the mounting member is disengaged from the door, allowing the door to open. An electronic device enclosure with the mounting apparatus is further offered.
US08723056B2 Electrical component cover for protecting wildlife
An electrical component cover may include a first portion and a second portion which are hingedly attached to one another and at least one projection extending from one of the first portion and the second portion. A locking member engages the at least one projection so as to hold the first portion and second portion together to cover an electrical component disposed in a void defined by the first portion and the second portion.
US08723052B1 Methods and apparatus for optimizing electrical interconnects on laminated composite assemblies
In some embodiments, a system includes a conductor on a first layer of a laminated composite assembly. The laminated composite assembly has an input, an output, a first electrical interconnect which couples the conductor on the first layer of the laminated composite assembly with a second conductor on a second layer of the laminated composite assembly, and a second electrical interconnect which electrically couples the first conductor with the second conductor. A width of the second electrical interconnect is greater than a width of the first electrical interconnect. A resistance of the laminated composite assembly as measured between the electrical input and the electrical output is less than the resistance of the laminated composite assembly as measured between the electrical input and the electrical output if the width of the first electrical interconnect were substantially equal to the width of the second electrical interconnect.
US08723045B2 Assembly for securing a wire harness to a sensor coupler
A coupler for connecting a vehicle wire harness to a vehicle sensor comprises a body having a first end and a second end. The first end is operably connected to the vehicle sensor. The second end is adapted to connect with a first section of the vehicle wire harness. An assembly is associated with the body for attaching a second section of the vehicle wire harness, which is spaced from the first section of the wire harness, to the coupler. The assembly includes an attachment member which is rotatable at least partially about a longitudinal axis defined by the coupler body. The rotation of the attachment member relative to the coupler allows the second section of the vehicle wire harness to be properly positioned relative to the coupler and the vehicle sensor.
US08723044B2 Flat cable deflection device and installation kit for an electrical installation with circuit integrity in case of fire
A flat cable deflection device with circuit integrity in case of a fire including a cylindrical cable deflection element made from fire resistant insulating material; and a support for the cylindrical cable deflection element made from fire resistant material. The support is offset from the cylindrical cable deflection element so that the support facilitates enveloping the cylindrical cable deflection element with a flat cable without the support contacting the flat cable. An electrical installation including at least one flat cable deflection device; at least one flat cable including plural high power current strands extending parallel adjacent to one another in a plane, where the flat cable runs over the deflection device and changes its direction at the deflection device, wherein the transversal cable direction in front and after the deflection device extends horizontally, and wherein the flat cable envelops the cylindrical cable deflection element at least partially.
US08723043B2 Electric conductor
This invention relates to an electrical conductor (25) which is composed at least partially of an electrically conductive material.According to the invention, at least part of the electrical conductor (25) is provided with a protective layer (11) whose specific electrical conductivity is lower, at least locally, than that of the electrically conductive material of the conductor (25).
US08723040B2 Terminal structure for wire harness
According to the present invention, in a terminal region of a coated wire, a swaged part formed at one end of a terminal fitting is swaged along an outer circumference of a coating part of the coated wire, and the terminal fitting is fixed to a terminal section of the coated wire. A molding resin is formed so as to completely coat the entire outer circumference of an exposed end region (a region including a fracture surface and a base edge) of the swaged part and its adjacent region.
US08723035B2 Vibration reduction rib
A method and apparatus for connecting a housing unit for an electronics module to an adapter member are disclosed. The method includes providing a housing with a first connection member and a second connection member, wherein the first connection member includes a flex rib and an abuse protection rib, attaching the first connection member to an adapter member, pivoting the housing on the first connection member to allow the second connection member to swing into position, and snapping the second connection member into the adapter member at an adapter member opening.
US08723030B2 Vulcanised power umbilical
A power umbilical, a DEH power cable or general umbilical, including a plurality of high power cables for transfer of large amounts of electric energy, filler material in the form of stiff elongate plastic elements located at least partially around and between the high power cables, which together are collectively gathered in a spiraled bundle by means of a laying and closing operation, and a protective sheath that encapsulates the high power cables and the filler material is shown. The high power cables are at intervals in the longitudinal direction of the cables, provided with frictional material which cooperate with the filler material for frictional engagement with and load transfer between each other.
US08723029B2 Electric cable device for fixing electric cable wires, connecting contact and method of manufacturing an electric cable
The invention relates to an electric cable (10) with at least four, preferably exactly four, wires (A, B, C, D) arranged in a first and a second pair, wherein each of the pairs comprises a first (A, B) and a second wire (C, D) each, wherein the wires (A, C) belonging to the first pair are arranged parallel to each other on a first plane at least in a first (11) and a third longitudinal section (13), and the wires (B, D) belonging to the second pair are arranged parallel to each other on a second plane and the two planes intersect in a line of intersection, wherein the line of intersection runs parallel to the wires (A, B, C, D) and the distances between one wire (A, B, C, D) each and the line of intersection are identical, wherein the angle of intersection (γ) between the planes is 90° in at least the first longitudinal section (11) and wherein the first wire (A) of the first pair is transposed with the first wire (B) of the second pair and the second wire (C) of the first pair is transposed with the second wire (D) of the second pair in a second longitudinal section (12), wherein the angle of intersection (α) between the planes is different from 90° at least in the third longitudinal section (13).
US08723027B2 Photovoltaic applications of non-conjugated conductive polymers
A photovoltaic structure having an electrode of a glass substrate coated with a high work function metal to which a film of a combination of a non-conjugated conductive polymer and an electron acceptor such as fullerene, carbon, iodine, or potassium iodide is applied. The structure has a second electrode of a low work function metal that has been coated on the glass substrate. This glass substrate with the low work function metal is applied to the film. Among the non-conjugated polymers are polyisoprene, poly(β-pinene), cis-polyisoprene, styrene-butadiene-rubber copolymer, polynobornene and polyalloocimene. When light strikes this photovoltaic structure it is capable of generating electric voltage greater than 100 mV for a light intensity of about 5 mW/cm2.
US08723023B2 Photovoltaic device with a discontinuous interdigitated heterojunction structure
A photovoltaic device which includes: a) a substrate based on a crystalline semi-conductor material; b) a first electrode which includes at least one heterojunction made on one face, referred to as the rear face, of the substrate, where this heterojunction includes a layer based on a doped amorphous semi-conductor material; and c) a second electrode. The first and second electrodes are arranged on the rear face of the substrate according to an interdigitated combs design, and where the layer includes multiple portions of the doped amorphous semi-conductor material which are unconnected and spaced apart from each other.
US08723022B2 Zinc ferrite thin film, method for manufacturing the same and application thereof
Electrochemical methods for manufacturing a zinc ferrite (ZnFe2O4) thin film include preparing an electrodeposition solution and forming the zinc ferrite thin film on a conductive substrate under suitable conditions. The electrodeposition solution includes about 10−2 M to about 10−1 M zinc nitrate aqueous solution and about 10−3 M to about 10−2 M ferric nitrate aqueous solution.
US08723018B2 Solar cell and method of manufacturing the same
A solar cell and a method of manufacturing the same are disclosed. The solar cell includes a substrate of a first conductive type; an emitter layer of a second conductive type opposite the first conductive type; at least one first electrode on the emitter layer and electrically connected to the emitter layer; a passivation layer on the substrate, the passivation layer including a plurality of exposing portions to expose respective portions of the substrate; and an electrode conductive layer on the passivation layer, the electrode conductive layer including a plurality of second electrodes electrically connected to the respective plurality of exposing portions, wherein in each of the plurality of exposing portions, an area of an exposed surface of the substrate is greater than an area of a virtual interface that is coplanar with an interface between the substrate and the passivation layer and which is located over the exposed surface.
US08723017B2 Dye sensitised solar cell
The present invention pertains to an electrode layer comprising a porous film made of oxide semiconductor fine particles sensitized with certain methin dyes. Moreover the present invention pertains to a photoelectric conversion device comprising said electrode layer, a dye sensitized solar cell comprising said photoelectric conversion device and to novel methin dyes.
US08723014B2 Musical tone control device, system and process
A musical tone control device capable of generating a hi-hat sound intended by the performer operates such that, when striking surface position information corresponds to a first position, instructions are provided to stop generating a musical tone with a first timbre (or that satisfies another predetermined condition), when the striking surface position has reached a predetermined second position higher than the first position after instructions are provided to generate the musical tone. Since, the performer's intention is reflected in the transition state of the striking surface position, a musical tone according to the performer's intention can be generated.
US08723011B2 Musical sound generation instrument and computer readable medium
There is provided a musical sound generation instrument. The instrument includes: a storage unit configured to store song data and audio data therein, wherein (a) the song data includes pitches and time information indicating sound generation timing of musical sounds of a song, and (b) the audio data is accompaniment data for the song of the song data; a musical sound data generator configured to generate musical sound data of prescribed musical sounds, based on manipulations of a plurality of playing elements; and an audio data player configured to read and play the audio data according to elapsed time information obtained by the time information included in the song data. The audio data player includes: a manipulation judging unit configured to determine whether manipulation timing of one of the playing elements synchronizes with the sound generation timing of the song data; and a player controller.
US08723008B1 Kick stand for snare drum
A snare drum kick stand having a base having at least one slot, with a front cradle is supported by front uprights fixably attached to the base, and a rear cradle supported by rear uprights attached to a rear cross bar; attached to the rear cross bar is at least one releasable fastener that slidably attaches to the at least one slot in the base; the front cradle has attached to it an end stop with at least one nub suitable for engaging the rim of a snare drum, and the rear cradle has a rear end stop; fixably attached to the base is a spur mounting plate and at least one spur is adjustably attached to the mounting plate with at least one spur fastener.
US08723006B1 Inbred corn line UTM03
An inbred corn line, designated UTM03, the plants and seeds of the inbred corn line UTM03, methods for producing a corn plant, either inbred or hybrid, produced by crossing the inbred corn line UTM03 with itself or with another corn plant, and hybrid corn seeds and plants produced by crossing the inbred line UTM03 with another corn line or plant and to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic corn plants produced by that method. This invention also relates to inbred corn lines derived from inbred corn line UTM03, to methods for producing other inbred corn lines derived from inbred corn line UTM03 and to the inbred corn lines derived by the use of those methods.
US08723002B1 Maize hybrid X18C097
A novel maize variety designated X18C097 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X18C097 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X18C097 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X18C097, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X18C097. This invention further relates to methods for producing maize varieties derived from maize variety X18C097.
US08723001B1 Maize variety X5S800
A novel maize variety designated X5S800 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing maize variety X5S800 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X5S800 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X5S800, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X5S800. This invention further relates to methods for producing maize varieties derived from maize variety X5S800 and to the maize varieties derived by the use of those methods.
US08723000B1 Maize variety hybrid X8T148
A novel maize variety designated X8T148 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X8T148 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X8T148 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X8T148, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X8T148. This invention further relates to methods for producing maize varieties derived from maize variety X8T148.
US08722999B1 Maize variety hybrid X95A923
A novel maize variety designated X95A923 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X95A923 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X95A923 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X95A923, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X95A923. This invention further relates to methods for producing maize varieties derived from maize variety X95A923.
US08722996B2 Plants and seeds of corn variety CV691958
According to the invention, there is provided seed and plants of the corn variety designated CV691958. The invention thus relates to the plants, seeds and tissue cultures of the variety CV691958, and to methods for producing a corn plant produced by crossing a corn plant of variety CV691958 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV691958 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV691958.
US08722992B2 Garden bean SB4534
A novel garden bean cultivar, designated SB4534, is disclosed. The invention relates to the seeds of garden bean cultivar SB4534, to the plants of garden bean line SB4534 and to methods for producing a garden bean plant by crossing the cultivar SB4534 with itself or another garden bean line. The invention further relates to methods for producing a garden bean plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other garden bean lines derived from the cultivar SB4534.
US08722988B2 Soybean cultivar S100242
A soybean cultivar designated S100242 is disclosed. The invention relates to the seeds of soybean cultivar S100242, to the plants of soybean cultivar S100242, to the plant parts of soybean cultivar S100242, and to methods for producing progeny of soybean cultivar S100242. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S100242. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S100242, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S100242 with another soybean cultivar.
US08722981B2 Soybean cultivar 11190435
A soybean cultivar designated 11190435 is disclosed. The invention relates to the seeds of soybean cultivar 11190435, to the plants of soybean cultivar 11190435, to the plant parts of soybean cultivar 11190435, and to methods for producing progeny of soybean cultivar 11190435. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 11190435. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 11190435, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 11190435 with another soybean cultivar.
US08722976B2 Soybean variety A1035502
The invention relates to the soybean variety designated A1035502. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1035502. Also provided by the invention are tissue cultures of the soybean variety A1035502 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1035502 with itself or another soybean variety and plants produced by such methods.
US08722971B1 Lettuce variety abilene
The present invention provides novel lettuce cultivar Abilene and plant parts, seed, and tissue culture therefrom. The invention also provides methods for producing a lettuce plant by crossing the lettuce plants of the invention with themselves or another lettuce plant. The invention also provides lettuce plants produced from such a crossing as well as plant parts, seed, and tissue culture therefrom.
US08722966B2 Plant expression constructs comprising and uses thereof
Methods of expressing a molecule of interest in a plant are disclosed. One method comprises contacting roots of the plant in a solution comprising at least one Geminivirus based expression construct so as to allow the at least one Geminivirus based expression construct to be absorbed by the roots, the expression construct comprising a polynucleotide encoding the molecule of interest, and further the expression construct being capable of systemic symptomless spread in a plant host, thereby expressing a molecule of interest in a plant. Expression constructs capable of systemic symptomless spread in a host plant are also disclosed.
US08722960B2 Systems and methods for wound protection and exudate management
The present invention provides systems and methods for protecting a wound and managing exudate released from the wound comprising a dressing having a support cushion for surrounding the wound and periwound region; a wicking strip for application in the periwound region between the support cushion and the wound; and a reservoir for application over the wicking strip, the wicking strip configured to transfer exudate from the wound to the reservoir, where the exudate is sequestered. Various alternative embodiments are described in which the wicking strip may be custom-fit to approximate an irregular wound margin, to apply a preferred pressure gradient to the periwound regions, to periodically apply fluids to the wound bed or to apply negative pressure wound therapy. Methods of applying the dressing also are provided.
US08722959B2 Reduced-pressure, compression systems and apparatuses for use on a curved body part
A system for providing a force to a desired area on a curved body part of a person includes a dressing assembly shaped and configured to be placed on the desired area of the person, a releaseable circumferential member surrounding the curved body part that holds the dressing assembly against the desired area, a sealing subsystem for providing a fluid seal over the dressing assembly and the person's skin, and a reduced-pressure subsystem for providing a reduced pressure to the dressing assembly. When reduced pressure is supplied, the system generates the force against the desired area on the curved body part.
US08722958B2 Method of decomposing waste plastic/organic material using titanium oxide granule with optimal particle property
Provided is a method of decomposing plastic and organic waste by using titanium oxide granules which are easily separated from metals and inorganic substances, have a highly efficient decomposing capability, and have a characteristic of fine powder formation resistance during pyrolysis. More specifically, the method of decomposing plastic and organic waste by using titanium oxide granules which are easily separated from metals and inorganic substances, have a highly efficient decomposing capability, and have a characteristic of fine powder formation resistance during pyrolysis has been established by optimizing the characteristics of titanium oxide granules.
US08722951B2 Fuel composition
This invention relates to fuel compositions for use in combustion engines, such as for motor vehicle and aircraft usage. The fuel composition contains at least 99.5% of aromatic hydrocarbons and paraffinic hydrocarbons. The composition also preferably contains no lead, no multi-ring compound (only single ring compounds are present), less than about 15 ppm sulfur, and/or less than about 5 ppm nitrogen species. The resulting fuel is a drop-in fuel that provides clean burning with little to no engine deposit, high lubricity, high stability, and low corrosion.
US08722950B2 Process for producing propylene and aromatics from butenes by metathesis and aromatization
The invention is for a process for producing propylene and hexene (along with ethylene, pentenes, product butenes, heptenes and octenes) by metathesis from butenes (iso-, 1- and cis and trans 2-) and pentenes and then aromatizing the hexenes (along with higher olefins, such as heptenes and octenes) to benzene (along with toluene, xylenes, ethylbenzene and styrene). Since the desired products of the metathesis reaction are propylene and hexene, the feed to the metathesis reaction has a molar ratio for 1-butene:2-butene which favors production of propylene and 3-hexene with the concentration of hexenes and higher olefins in the metathesis product being up to 30 mole %. An isomerization reactor may be used to obtain the desired molar ratio of 1-butene:2-butene for the feed composition into the metathesis reactor. After the metathesis reaction, of hexene and higher olefins are separated for aromatization to benzene and other aromatics.
US08722947B2 Gas oil composition
The present invention provides a gas oil composition for use in a diesel engine containing an FT synthetic base oil and having a sulfur content of 5 ppm by mass or less, an oxygen content of 100 ppm by mass or less, a bulk modulus of 1250 MPa or greater and 1450 MPa or less, a saybolt color of +22 or greater, a lubricity of 400 μm or less, an initial boiling point of 140° C. or higher and an end point of 380° C. or lower in distillation characteristics, wherein: (1) the cetane number in a fraction range of lower than 200° C. is 20 or greater and less than 40; (2) the cetane number in a fraction range of 200° C. or higher and lower than 280° C. is 30 or greater and less than 60; and (3) the cetane number in a fraction range of 280° C. or higher is 50 or greater.
US08722944B2 Process for olefin etherification
The invention relates to processes for the etherification of olefins with alcohols. According to one aspect, a heterogeneous etherification catalyst is used under conditions that permit limiting the contact time between the desired product and the catalyst, thereby mitigation reverse reactions. According to a second aspect, a recycling process is used that significantly increases the yield of desired product.
US08722941B2 Process for preparing alkyl hydroperoxide compounds
A method for making alkyl hydroperoxide compounds, specifically the preparation of cyclohexyl hydroperoxide is described. The preparation of cyclohexyl hydroperoxide by means of the oxidation of cyclohexane by oxygen in a multi-stage reactor or in reactors connected in series is also described. In these methods, the reactor surfaces in contact with the oxidation medium can be protected by a layer of heat-resistant PFA polymer.
US08722940B2 High molybdenum mixed metal oxide catalysts for the production of unsaturated aldehydes from olefins
A catalyst for the oxidation of an olefin to an unsaturated aldehyde comprising a mixed metal oxide having the formula (I): MoaWbMcM′dM″eZfOg  (I) where M represents trivalent metals, M′ represents divalent metals, M″ represents monovalent metals, Z represents elements in the form of an oxide, a, b, c, d, e, f and g are numbers, and where the catalyst has an anion to cation molar (ACM) ratio greater than 1.00 and less than 2.00 and an M′ to M molar ratio between 1.95 and 2.15.
US08722939B2 Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis
The present invention relates to the identification of provided cyclohexane-1,3-diones (CHD compounds) and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the provided CHD compounds.
US08722936B2 Low-VOC polyamines
A compound having formula (I) wherein R1, R2, R3, R4, R5 and R6 independently are hydrogen, C1-C10 alkyl, C5-C10 cycloalkyl, C6-C10 aryl or C7-C20 aralkyl; X is a difunctional group selected from the group consisting of C2-C20 alkyl, C5-C20 cycloalkyl, C6-C10 aryl, C8-C20 aryl alkyl, C4-C20 heteroalkyl or C10-C20 aryl heteroalkyl.
US08722935B2 Process for conversion of isobutylene to tertiary butylamine
The invention discloses an improved process for the conversion of isobutylene to tertiary butylamine with conversion up to 50% at pressure lower than 40 bar.
US08722934B2 Diphenylmethane compound
Compounds having a diphenylmethane skeleton are superior in broad utility and stability, and are useful as a protecting reagent (anchor) of amino acid and/or peptide in the liquid phase synthesis and the like of a peptide having a C-terminal etc., which are of a carboxamide(-CONHR)-type, and in organic synthetic reaction methods (particularly peptide liquid phase synthetic methods), and may be contained in a kit for peptide liquid phase synthesis.
US08722933B2 Method for preparing metal complexes of polydentate beta-ketoiminates
A method for making a group 2 metal-containing polydentate β-ketoiminate represented by the following structure A: wherein M is a metal selected from the group consisting of Mg, Ca, Sr, and Ba; R1, R3, R5, and R6 are independently selected from an alkyl group, a fluoroalkyl group, a cycloaliphatic group, and an aryl group; R2 is selected from a hydrogen atom, an alkyl group, an alkoxy group, a cycloaliphatic group, and an aryl group; and R4 is an alkyenyl bridge, comprising: reacting M in a reaction mixture comprising a tridentate ketoimine ligand and an alcohol comprising at least one selected from the group consisting of R7OH and (OH)nR8 wherein R7 and R8 are independently selected from an alkyl group and an aryl group. In certain embodiments, the reaction mixture further comprises an organic solvent.
US08722929B2 N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators
This invention provides compounds of formula A and formula B which are modulators of potassium ion channels and are useful for the treatment of seizure disorders.
US08722928B2 Stable and non-precipitating aqueous compositions containing the potassium salt of (S)-(+)-abscisic acid, and methods of their preparation and use
The present invention generally relates to aqueous compositions containing salts of (S)-(+)-abscisic acid, the surfactant Atlox™ 4913, and the color stabilizers sodium citrate and sodium acetate, methods of their preparation, and methods of their agricultural use.
US08722926B2 Beta-ketocarbonylquat compounds and process for the preparation thereof
β-ketocarbonylquats contain at least one quaternary ammonium salt group, and may be prepared by the reaction of an alkyl ketene dimer with a tertiary amine group-containing compound also containing a protic group, followed by quaternization.
US08722923B2 Conjugates for treating neurodegenerative diseases and disorders
A conjugate comprising L-DOPA covalently linked to at least one γ-aminobutyric acid (GABA) moiety, an ester and/or an addition salt thereof are disclosed, as well as uses thereof for treating a neurodegenerative disease or disorder.
US08722922B2 Process for hydrogenation of polycarboxylic acids or derivatives therof
The disclosure provides a process for hydrogenation of polycarboxylic acids or derivatives thereof, including: hydrogenation of polycarboxylic acids or derivatives thereof in the presence of a catalyst, wherein the catalyst includes an active metal and a support, the support includes a Group IIA element and a Group IIIA element, and the active metal includes a Group VIIIB element.
US08722921B2 Process for reduction of alpha-acyloxy sulfide derivatives
The present invention provides an efficient and scalable process to prepare the compound of formula 4 by reduction of the corresponding α-acyloxy sulfides.
US08722919B2 Process for production of mono-substituted alkylated compound using aldimine or derivative thereof
The present invention provides a method for producing asymmetrical mono-substituted alkylated compounds of α-amino acids that are represented by a specific formula, using an aldimine-type Schiff base. In the method of the present invention, the process of alkylating an aldimine-type Schiff base in a medium in the presence of an optically-active quaternary ammonium salt phase-transfer catalyst and an inorganic base is initiated, and subsequently the reaction is quenched at a time earlier than a time for completion of the stoichiometric reaction of the alkylation reaction, so that a mono-substituted alkylated product with high optical purity can be obtained.
US08722918B2 Process for producing Cl-C4 alkyl nitrite
The present invention relates to a process for producing C1-C4 alkyl nitrite, comprising loading a resin catalyst layer and/or a porous filler layer into a reactor, passing nitrogen oxide, oxygen and C1-C4 alkanol as raw materials through the resin catalyst layer and/or porous filler layer in a counter current, parallel current or cross current manner, reacting under the conditions including a reaction temperature of from 0 to 150° C., a reaction pressure of from −0.09 to 1.5 MPa, a molar ratio of C1-C4 alkanol/nitrogen oxide of 1-100:1, a molar ratio of nitrogen oxide/oxygen of 4-50:1, to obtain an effluent containing C1-C4 alkyl nitrite, wherein said nitrogen oxide is NO, or a mixed gas containing NO and one or more selected from N2O3 and NO2.
US08722914B2 Silaoxacycles
Siloxacycles are synthesized in high yield and purity by reaction of acyloxymethyl (alkoxy) silanes in the presence of a catalyst which is a metal from groups 3 to 15 of the periodic table, or a compound thereof.
US08722913B2 Method for producing higher silanes
The invention relates to a method for producing dimeric and/or trimeric silicon compounds, in particular silicon halogen compounds. The claimed method is also suitable for producing corresponding germanium compounds. The invention also relates to a device for carrying out said method to the use of the produced silicon compounds.
US08722908B2 Method for producing glycolide
A method for producing glycolide, including the steps of: heating a mixture containing a glycolic acid oligomer, a high-boiling point polar organic solvent having a boiling point of 230 to 450° C., and a tin compound under normal pressure or reduced pressure until a temperature at which the glycolic acid oligomer is depolymerized, to thereby dissolve the glycolic acid oligomer in the high-boiling point polar organic solvent; heating a solution, in which the glycolic acid oligomer is dissolved, under normal pressure or reduced pressure until a temperature at which the glycolic acid oligomer is depolymerized, to thereby form glycolide by depolymerization of the glycolic acid oligomer in the solution; and co-distilling off the high-boiling point polar organic solvent and the formed glycolide from a depolymerization reaction system.
US08722900B2 Process for cabazitaxel, and intermediates thereof
The present invention relates to processes for making cabazitaxel, cabazitaxel analogues and intermediates thereof. The invention provides novel compounds useful in the synthesis of cabazitaxel.
US08722894B2 1,3-disubstituted-4-phenyl-1H-pyridin-2-ones
The present invention relates to novel compounds, in particular novel pyridinone derivatives according to Formula (I) wherein all radicals are as defined in the application and claims. The compounds according to the invention are positive allosteric modulators of metabotropic receptors—subtype 2 (“mGluR2”) which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. In particular, such diseases are central nervous system disorders selected from the group of anxiety, schizophrenia, migraine, depression, and epilepsy. The invention is also directed to pharmaceutical compositions and processes to prepare such compounds and compositions, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR2 is involved.
US08722886B1 Methods for the total chemical synthesis of enantiomerically-pure 7-(2′-trimethylsilyl)ethyl camptothecin
The present invention discloses and claims five (5) novel, highly efficient synthetic routes for the total synthesis of enantiomerically-pure (i.e., 99%) 7-(2′-trimethylsilyl)ethyl camptothecin (BNP1350; Karenitecin; Cositecan). These aforementioned synthetic schemes are the first to disclose the total syntheses of 7-(2′-trimethylsilyl)ethyl camptothecin using a highly novel direct, non-linear and convergent synthetic strategy which involves annealing the key C7-(trimethylsilyl)ethyl side chain-bearing A ring key synthons to an enantiomerically-pure tricyclic pyridone; rather than through the conventional methodology which incorporates the C7-(trimethylsilyl)ethyl side chain as the final synthetic step on a totally synthesized camptothecin parent compound. The current novel synthetic approaches reported herein since utilize desirably functionalized A-ring with preinstalled trimethyl silyl ethyl side chain, the aforementioned synthetic methodologies have a wider scope of making wide range of pharmaceutically relevant A-ring substituted BNP1350 analogs by substituting desirably functionalized nitro or protected amino phenyl carboxy A-ring as the starting material.
US08722885B1 Phosphorescent four-coordinated platinum (II) complex
A phosphorescent four-coordinated platinum (II) complex represented by formula (C) is disclosed: where Y represents N or P; R1, R2, R3, R4, R5, R6, R9, R10, R11, and R12 are the same or different, and independently represent hydrogen, or a substituted or unsubstituted organic group; and represents or
US08722880B2 Method for preparing 42-(dimethylphosphinate) rapamycin
A method for preparing 42-(dimethylphosphinate) Rapamycin (Ridaforolimus) (I) is provided, which has advantages of high conversion rate and no 31,42-bis(dimethyl phosphinate) Rapamycin (III) generated. In the method of the present invention, Rapamycin (II) is firstly reacted with triethyl chlorosilane in a base condition to form 31,42-bis(triethylsilylether) Rapamycin (IV-b), followed by a selective deprotection process to obtain 31-triethylsilylether Rapamycin (V-b). Next, a phosphorylation reaction is performed by using dimethylphosphinic chloride under a base solution to obtain a crude product. Finally, a deprotection reaction is performed in a diluted sulfuric acid solution to obtain a crude product of Ridaforolimus (I). Since the conversion rate of each step of the method of the present invention is higher than 98%, it indicates that the method of the present invention is suitable for industrial production.
US08722879B2 Redox-active structures and devices utilizing the same
A device is presented having reversibly changeable and optically readable optical properties. The device comprises a substrate having an electrically conductive surface and carrying a redox-active layer structure. The redox-active layer structure may be a monolayer or a multi-layer structure and is configured to have at least one predetermined electronic property including at least one of electrodensity and oxidation state. The electronic property of the layer structure defines an optical property of the structure thereby determining an optical response of the structure to certain incident light. This at least one electronic property is changeable by subjecting the redox-active layer structure to an electric field or to a redox-active material. The device thus enables effecting a change in said electronic property that results in a detectable change in the optical response of the layer structure.
US08722877B2 7-deazapurine modulators of histone methyltransferase, and methods of use thereof
Disclosed are compounds, pharmaceutical compositions containing the compounds, uses of the compounds and compositions as modulators of histone methyltransferases, and methods for treating diseases influenced by modulation of histone methyltransferase activity.
US08722875B2 Means for inhibiting the expression of Orc-1
The present invention is related to a nucleic acid molecule comprising a double-stranded structure, whereby the double-stranded structure comprises a first strand and a second strand, whereby the first strand comprises a first stretch of contiguous nucleotides and said first stretch is at least partially complementary to a target nucleic acid, and whereby the second strand comprises a second stretch of contiguous nucleotides and said second stretch is at least partially complementary to the first stretch, whereby the first stretch comprises a nucleic acid sequence which is at least complementary to a nucleotide core sequence of the nucleic acid sequence according to SEQ ID NO: 1, whereby the nucleotide core sequence comprises the nucleotide sequence from nucleotide positions 1755 to 1763 of SEQ ID NO: 1; from nucleotide positions 1904 to 1912 of SEQ.ID.No.1; from nucleotide positions 1905 to 1913 of SEQ ID NO: 1; from nucleotide positions 2548 to 2556 of SEQ ID NO: 1; whereby the first stretch is additionally at least partially complementary to a region preceding the 5′ end of the nucleotide core sequence and/or to a region following the 3′ end of the nucleotide core sequence.
US08722867B2 Gene therapy vectors and cytosine deaminases
This disclosure provides modified cytosine deaminases (CDs). The disclosure further relates to cells and vector expressing or comprising such modified CDs and methods of using such modified CDs in the treatment of disease and disorders.
US08722864B2 Glycosylated acetaminophen pro-drug analogs
The present invention relates to methods and compositions for the synthesis, production, and use of pro-drug analogs of the analgesic acetaminophen. This invention relates to a method for the production of a broad group of glycosides of acetaminophen derivatives.
US08722860B2 Anti-TNF-α antibodies and their uses
The present disclosure relates to antibodies directed to the tumor necrosis factor alpha (“TNF-α”) and uses of such antibodies, for example, to treat diseases associated with the activity and/or overproduction of TNF-α.
US08722854B2 Degradation-stabilised, biocompatible collagen matrices
The present invention relates to degradation-stabilized, biocompatible collagen matrices which are distinguished in particular by the fact that they contain soluble collagen and peptide constituents, to processes for the preparation of such collagen matrices, which processes include in particular chemical crosslinking with an epoxy-functional crosslinking agent, and to the use of the collagen matrices according to the invention as a cosmetic or pharmaceutical agent, in particular for topical use, and as a wound treatment agent, as an implant or as a haemostatic agent in humans or animals, and as a scaffold for cell population in the biotechnology, basic research and tissue engineering field.
US08722846B2 Preparation of homopolymer and copolymers of (phosphonyl)aromatic diesters and acids
The composition of a homopolymer of (phosphonyl) aromatic diester compound using a catalyst and a glycol is provided. Further, the composition of a copolymer of the (phosphonyl) aromatic diester compound using a catalyst, a glycol and a second diester is provided. These polymers find application as flame retardants during synthesis of various polymeric materials.
US08722844B1 Methods for preparing polyamide compositions
A polyamide composition is formed by combining a phosphorous containing catalyst with monomer starting materials under conditions suitable to cause polymerization of the monomer starting material into a low molecular weight polyamide material. The polyamide material, which may include remaining or residual catalyst, is then further polymerized via solid state polycondensation at a temperature suitable to form a high molecular weight polyamide material. The presence of the catalyst results in increased solid state polymerization rate and a final polyamide material composition with increased viscosity and a higher molecular weight.
US08722831B2 Process for production of cross copolymers, cross copolymers obtained by the process, and use thereof
To provide a novel cross copolymer and resin composition which are improved in heat resistance and compatibility over conventional ethylene/aromatic vinyl compound copolymers and which have low crystallinity, are excellent in softness, transparency and compatibility and show mechanical properties similar to soft vinyl chloride resins, as compared with conventional cross copolymers.A process for producing a cross copolymer, which comprises a coordination polymerization step and a subsequent anionic polymerization step, wherein in the coordination polymerization step, copolymerization of an olefin monomer, an aromatic vinyl compound monomer and an aromatic polyene is carried out by using a single-site coordination polymerization catalyst to synthesize an olefin/aromatic vinyl compound/aromatic polyene copolymer, and then, in the anionic polymerization step, polymerization is carried out in the coexistence of such an olefin/aromatic vinyl compound/aromatic polyene copolymer and an anionic polymerizable vinyl compound monomer by using an anionic polymerization initiator.
US08722830B2 Polymer-dendrimer hybrids
The present invention relates to a branched vinyl polymer carrying dendrons made from monofunctional vinyl monomers and branched by virtue of difunctional vinyl monomers so that there is on average one branch or fewer per polymer chain to avoid gelation. The polymer may be made by chain-growth polymerization of predominantly monofunctional vinyl monomers in the presence of difunctional vinyl monomers and dendron units.
US08722829B2 Cold-sealed, recloseable pack and composition for producing it
Described is a recloseable pack having a cold-sealed layer of adhesive which is recloseable after the pack has been opened, the layer of adhesive comprising an emulsion polymer composed to an extent of at least 60% by weight of principal monomers selected from the group consisting of C1 to C20 alkyl (meth)acrylates, vinyl esters of carboxylic acids comprising up to 20 C atoms, vinylaromatics having up to 20 C atoms, ethylenically unsaturated nitriles, vinyl halides, vinyl ethers of alcohols comprising 1 to 10 C atoms, aliphatic hydrocarbons having 2 to 8 C atoms and one or two double bonds, and mixtures of these monomers, the emulsion polymer being preparable by emulsion polymerization of free-radically polymerizable monomers in the presence of at least one protective colloid. Also described are aqueous polymer dispersions suitable for producing the pack of the invention, and polymer films coated with the polymer dispersions.
US08722828B2 Process for continuous production of cycloolefin resins, and sheets or films thereof, using ring opening metathesis polymerization
A process (1) for producing a cycloolefin resin film comprising the steps of: the step (I) of mixing a cycloolefin monomer and a metathesis polymerization catalyst to prepare a polymerizable composition (A); the step (II) of coating or impregnating the supporting body with the polymerizable composition (A) at once after the step (I), and the step (III) of polymerizing the polymerizable composition (A) by polymerization; and a process (2) for producing a cycloolefin polymer sheet or film with the thickness of 1 mm or less comprising polymerizing a reactive solution containing a ruthenium complex catalyst, having a hetero atom-containing carbene compound as a ligand, and a cycloolefin monomer by ring-opening metathesis bulk polymerization, wherein the polymerization of the cycloolefin monomer is completed by heating the reactive solution to 100° C. or higher at the heating rate of 20° C./min or more. Thus, a cycloolefin resin film having excellent adhesion to other materials and a cycloolefin polymer sheet or film having a thickness of 1 mm or can be efficiently produced.
US08722827B2 Cross-linkable polyolefin composition comprising two types of silane groups
The present invention relates to a polyolefin composition comprising a cross-linkable polyolefin with (A) hydrolysable silane groups which upon hydrolysation form an acid or a base, (B) hydrolysable silane groups different from silane groups (A).
US08722826B2 Zwitterionic terpolymers, method of making and use on medical devices
Biocompatible terpolymers are manufactured to include a zwitterionic monomer, an alkoxy acrylate monomer, and a hydrophobic monomer.
US08722825B2 Surface active additive and photoresist composition comprising same
A polymer comprises the polymerized product of monomers comprising a nitrogen-containing monomer comprising formula (Ia), formula (Ib), or a combination of formulas (Ia) and (Ib), and an acid-deprotectable monomer having the formula (II): wherein a is 0 or 1, each Ra is independently H, F, C1-10 alkyl, or C1-10 fluoroalkyl, L1 is a straight chain or branched C1-20 alkylene group, or a monocyclic, polycyclic, or fused polycyclic C3-20 cycloalkylene group, each Rb is independently H, C1-10 alkyl, C3-20 cycloalkyl, C3-20 heterocycloalkyl, an aliphatic C5-20 oxycarbonyl, or a C1-30 acyl group optionally including a heteroatom substituent group, where each Rb is separate or at least one Rb is attached to an adjacent Rb; LN is a nitrogen-containing monocyclic, polycyclic, or fused polycyclic C3-20 heterocycloalkylene group, and X is H, C1-10 alkyl, aliphatic C5-20 oxycarbonyl, or a C1-30 acyl group optionally including a heteroatom substituent group; and each Rc is independently C1-10 alkyl, C3-20 cycloalkyl, or C3-20 heterocycloalkyl, wherein each Rc is separate or at least one Rc is attached to an adjacent Rc.
US08722822B2 Aqueous emulsion and production method thereof
This invention provides an aqueous emulsion, which comprises a polyvinyl alcohol-based resin, as the dispersant, and a polymer comprising a structural unit derived from an ethylenically unsaturated monomer, as the dispersoid, from which a film having excellent transparency can be obtained, and which is excellent in mechanical stability, chemical stability, freezing stability and storage stability, and a method for producing the same, and relates to an aqueous emulsion which has an average particle size of the dispersoid of from 100 to 450 μm and an apparent grafting efficiency of the polyvinyl alcohol-based resin of from 65 to 75% based on the dispersoid, and a method for producing the same.
US08722819B2 Process for producing high molecular weight polyethylene
In a process for producing polyethylene having a molecular weight of at least 3×105 g/mol as determined by ASTM 4020, ethylene is contacted under polymerization conditions with a slurry of a catalyst composition comprising a Group 4 metal complex of a phenolate ether ligand, wherein the slurry further includes a scavenger comprising an alkyl magnesium compound.
US08722818B2 Method and apparatus for monitoring and restoring electrical properties of polymerization reactor wall film
Described herein are methods for monitoring and restoring electrical properties of polymerization reactor wall films. The method may comprise using a reactor wall monitor to monitor and determine an electrical property, such as the bed voltage or breakdown voltage, of the wall film. The method may further comprise adding continuity additive to the reactor and/or adjusting the feed rate of continuity additive being added to the reactor in response to the measured electrical property.
US08722817B2 Process to make long chain branched (LCB), block, or interconnected copolymers of ethylene
A process is taught, comprising polymerizing ethylene in the presence of a catalyst to form a crystalline ethylene-based polymer having a crystallinity of at least 50% as determined by DSC Crystallinity in a first reactor or a first part of a multi-part reactor and reacting the crystalline ethylene-based polymer with additional ethylene in the presence of a free-radical initiator to form an ethylenic polymer in at least one other reactor or a later part of a multi-part reactor.
US08722816B2 Solder resist, dry film thereof, cured product, and printed wiring board
A solder resist having both adequate sensitivity at photo-irradiation and alkali developability, and the solder resist forming a cured product which is excellent in dimensional stability against temperature change, does not exhibit brittleness, and further, is excellent in water resistance, electrical insulation, thermal cycle test resistance (TCT resistance) and the like is provided, and further, a dry film having a solder resist layer, a cured product and a printed wiring board are provided. The solder resist comprising an acid-modified vinyl ester synthesized from an epoxy compound, a phenol compound, an unsaturated monobasic acid and a polybasic acid anhydride, wherein the epoxy compound contains a crystalline epoxy resin having a melting point of 90° C. or more, and the phenol compound contains a compound having a bisphenol S structure.
US08722815B2 Two-component moisture curable coating compositions
A two-package moisture curable composition is provided. The composition comprises a first part comprising at least one silane terminated polyurethane and a second part comprising at least one silanol terminated polysiloxane; wherein the silane terminated polyurethane based polymer has at least one end group of the general formula: —A—(CH2)m-SiR1n(OR2)3-n, where A is a urethane or urea linkage group, R1 is selected from C1-12 alkyl, alkenyl, alkoxy, aminoalkyl, aryl and (meth)acryloxyalkyl groups, R2 is each substituted or unsubstituted C1-1-8 alkyl or C6-C20 aryl groups, m is an integer from 1 to 60 and n is an integer from 0 to 1; wherein the silane terminated polyurethane is prepared using natural oil polyols and their derivatives; and wherein the composition, after moisture cured, forms a surface whose water contact angle is larger than 101°. The composition is suitable for applications in antifouling coatings which afford low surface energy and improved mechanical performance.
US08722807B2 Polymer composition for injection moulding
The application relates to a polyethylene composition having a base resin, the base resin comprising (A) a first polyethylene fraction, and (B) a second polyethylene fraction, wherein the melt flow rate MFR5/190° c. of the first fraction is higher than the melt flow rate MFR5/190° c. of the second fraction, the flow rate ratio FRR21/5 of the polyethylene composition, defined as the ratio of melt flow rate MFR21-6/190° c. to melt flow rate MFR5/190° c., is within the range of 15-28, and 10 the melt flow rate MFR5/190° c. of the polyethylene composition is within the range of 0.5-1.1 g/10 min.
US08722805B2 High flowability long chain branched polypropylene
The present invention relates to a polypropylene composition showing a high melt flow rate and high melt strength while maintaining high impact strength. The composition of the present invention is obtainable by using a low molecular weight linear isotactic polypropylene as melt flow enhancer for a high molecular weight polypropylene having a high melt strength and impact strength. The inventive composition could be used for the production of different articles.
US08722801B2 Process for producing hydrolyzable silyl group-containing fluoropolymer, and composition containing hydrolyzable silyl group-containing fluoropolymer
The present invention has an object to provide a process for producing a hydrolyzable silyl group-containing fluoropolymer which is excellent in storage stability and has a sufficient pot life. At the time of producing a hydrolyzable silyl group-containing fluoropolymer by reacting an isocyanate group of an isocyanate group-containing alkoxysilane to a hydroxy group of a hydroxy group-containing fluoropolymer, the reaction is carried out in the presence a compound containing a specific metal atom at a certain concentration.
US08722800B2 Composition for stretchable film
The present invention provides a composition for a stretchable film, which achieves a high-level balance between a high elastic modulus and a small permanent elongation, which is excellent in adhesive force when laminated with a non-woven fabric or the like, and also has good formability. The present invention also provides a composition for a stretchable film comprising a block copolymer composition containing a block copolymer A represented by the following general formula (A) and a block copolymer B represented by the following general formula (B), and a polyolefin-based thermoplastic resin: Ar1a-Da-Ar2a  (A) (Arb-Db)n-X  (B), in these formulas, Ar1a and Arb each represent an aromatic vinyl polymer block having a weight average molecular weight of 6,000 to 20,000; Ar2a represents an aromatic vinyl polymer block having a weight average molecular weight of 40,000 to 400,000; Da and Db each represent a conjugated diene polymer block having a vinyl bond content of 1 mol % to 20 mol %; X represents a single bond or a residue of a coupling agent; and n represents an integer of 2 or greater.
US08722794B2 Melt processable copolyetheramide elastomers
The present invention relates to a melt processable copolyetheramide made by reacting (a) one or more segments of polyamide hard blocks derived from a lactam-terminated diisocyanate and a lactam monomer, and (b) one or more segments of polyether soft blocks derived from a polyether diol. The invention further provides for methods of making said copolyetheramide, including a continuous extruder method of production.
US08722793B2 Polylactic acid resin composition, polylactic acid resin molded article and method for producing polylactic acid resin composition
A polylactic acid resin composition contains (A) a crosslinked polylactic acid resin and (B) a flame retardant additive.
US08722788B2 Transparent TPU (thermoplastic polyurethanes)/PMMA (polymethyl (meth) acrylate) blends with improved low-temperature impact resistance
The invention describes transparent plastics mixtures having low-temperature impact resistance composed of a thermoplastic polyurethane (TPU) and of an impact-modified poly(meth)acrylate (PMMA).
US08722787B2 Coating composition and articles made therefrom
The present disclosure includes a waterborne polyolefin based coating layer that has improved features as compared to epoxy coatings. The coating composition of the present disclosure include 40 to 80 weight percent (wt. %) of a base polymer; 10 to 30 wt. % of a polymeric stabilizing agent; 5 to 15 wt. % of a polymeric coupling agent; 0 to 35 wt. % of a polymeric performance improving agent; a neutralizing agent that partially or fully neutralize the polymeric stabilizing agent; and a fluid medium, where the wt. % values are based on the total weight of the base polymer, the polymeric coupling agent, the polymeric stabilizing agent and, when present, the polymeric performance improving agent (as used herein, this total weight of the base polymer, the polymeric coupling agent, the polymeric stabilizing agent and, when present, the polymeric performance improving agent may be referred to as the “solid content” of the coating composition).
US08722780B2 Perfluoroelastomer composition and molded article hereof
The present invention provides a perfluoroelastomer composition comprising: a perfluoroelastomer having a nitrogen-containing curing site; and a catalyst mixture comprising: a tertiary amine; and an organic dicarboxylic acid represented by general formula (1) or (2) in an amount of 0.4 to 2 mol per mol of the tertiary amine: HOOC—COOH  (1) HOOC-A-COOH  (2) wherein A in formula (2) is an alkyl group having 1 to 10 carbon atoms or a phenyl group, which may be partially or fully fluorinated. Also disclosed is a perfluoroelastomer molded article obtained from the composition.
US08722778B2 UV protective compositions, processes for preparing such compositions, methods of coating substrates therewith and multi-layer articles formed thereby
Compositions, suitable for coating surfaces, methods for their preparation and for coating surfaces therewith, where said compositions comprise: (a) 100,000 parts by weight of a primer composition comprising a binder material (a1), a primer solvent (a2) and a UV absorber (a3), wherein the primer composition is suitable as an adhesion-promoting agent between a thermoplastic substrate and a siloxane-based top coat; (b) 0 to 900,000 parts by weight of a solvent, and (c) 1 to 3000 parts by weight of a compound according to the general formula (I): wherein X represents a moiety selected from the group consisting —OR6, —OCH2CH2OR6, —OCH2CH(OH)CH2OR6 and —OCH(R7)COOR8, wherein R6 represents a branched or unbranched C1-C13 alkyl, C2-C20 alkenyl, C6-C12 aryl or —CO—C1-C18 alkyl, R7 represents H or a branched or unbranched C1-C8 alkyl, and R8 represents a C1-C12 alkyl, a C2-C12 alkenyl or a C5-C6 cycloalkyl, and wherein the composition has a viscosity of 40 s to 140 s measured in accordance with DIN EN ISO 2431 at 23° C. and with a 2 mm cup.
US08722777B2 Highly loaded concentrate pellets and preparation of the same
A highly loaded concentrate pellet composition includes an active ingredient in a concentration of at least about 60% by weight, and a low molecular weight binder in a concentration of up to about 35% by weight. The active ingredient is substantially evenly dispersed in the binder. The binder has a melting point that permits the composition to melt under shear in an extruder. The binder is non-metallocene and non-stearic.
US08722771B2 Sulfur modified asphalt for warm mix applications
Disclosed herein are an asphalt concrete mixture, an asphalt binder composition, and methods of preparing the related compositions. The asphalt binder compositions include a polyphosphoric acid, a macromolecular polymer having a saturated backbone with macromolecular modifications, sulfur, and non-surfactant additives based on wax chemistry. The compositions are capable of being performance graded and being used in warm mix asphalt applications.
US08722770B2 Unsaturated polyester resin or vinyl ester resin compositions
The present invention relates to an unsaturated polyester resin or vinyl ester resin composition, wherein the unsaturated polyester resin or vinyl ester resin composition comprises an unsaturated polyester resin or vinyl ester resin and a copper compound and an acetoacetamide compound having the following formula: whereby R1, R2, R3, R4 and R5 each individually may represent hydrogen (H), or a C1-C20 alkyl, C6-C20 aryl, alkylaryl or arylalkyl group, that each optionally may contain one or more hetero-atoms (e.g. oxygen, phosphor, nitrogen or sulphur atoms) and/or substituents; a ring may be present between R1 and R2, R2 and R3, R3 and R5 and/or between R4 and R5; R4 and R5 may be part of a polymer chain or may be attached to a polymer chain; and the resin being curable with a peroxide and the resin composition contains less than 0.01 mmol cobalt per kg primary resin system and less than 0.01 mmol titanium per kg primary resin system.
US08722769B2 Light-curing resin composition and optical material
A light-curing resin composition includes an epoxy resin having two or more epoxy groups in one molecule; a photopolymerization initiator including an anion component and a cation component; and an aralkyl compound having an alcoholic hydroxyl group.
US08722766B2 Method for the solvent-free production of thermoplastic dispersions
Disclosed is a method for the production of thermoplastic polymer dispersions, using a reaction vessel with a first volume and a secondary volume, wherein a first stirrer is located and operative in said first volume and a secondary stirrer is located and operative in said secondary volume, wherein the first volume is at least 20 times larger than the secondary volume, wherein the stirrers in both volumes are able to handle viscosities above of or equal to 1000 mpas, including the steps of a.) loading the first volume of the vessel with an initial amount of polymer and optionally water and optionally alkaline; b.) heating the vessel externally to a target process temperature in the range of 80-300° C.; c.) operating the first stirrer in the first volume for at least half an hour at a speed of in the range of 10-100 rpm; d.) addition of water and optionally alkaline to the first volume; e.) connection of the secondary volume to the first volume and operating the secondary stirrer in the secondary volume at a speed of above 1000 rpm and recycling the reaction product through said secondary stirrer while keeping the operating temperature essentially constant during a timespan in excess of the recycle ratio3 of the primary and the secondary mixer to form the dispersion. Furthermore disclosed is a dispersion as obtainable using such a method and a reaction vessel for carrying out such a method.
US08722765B2 Alumina particle composite, method of manufacturing the alumina particle composite, resin composition and method of manufacturing the resin composition
An alumina particle composite (1) includes an alumina particle (2) and an organic acid (3) chemically bonded to a surface of the alumina particle (2). Further, the alumina particle (2) has a short axis length of 1 to 10 nm, a long axis length of 20 to 400 nm, and an aspect ratio of 5 to 80, and is represented by Formula I, Al2O3·nH2O  Formula I where n is 0 or more.
US08722761B2 Plastic surfaces having improved surface characteristics
The disclosure provides a melt processible theromoplastic composition, comprising a major proportion of a base polymer comprising a first melt processible thermoplastic polymer having a first Fedor's solubility parameter and a first viscosity; and a combination of a carrier polymer and a surface modifying additive, the carrier polymer comprising a second melt processible thermoplastic polymer which has a second Fedor's solubility parameter that is at least about 2.5 (J/cm3)1/2 lower than the first Fedor's solubility parameter, and a second viscosity, the carrier polymer being adhered to the surface modifying additive, and wherein the first viscosity is at least about 10 times the second viscosity.
US08722760B2 Self-adhesive compositions including a plurality of acidic compounds
The present invention provides self-adhesive compositions that include a plurality of acidic compounds. The self-adhesive compositions are useful for applications including, for example, restoring dental structures and adhering orthodontic appliances to teeth.
US08722758B2 Water soluble polyimide resin, its preparation and use
The present invention relates to a novel water soluble polyimide resin, which contains a hydrophilic functional group such as —OH, —COOH to increase the solubility of the polyimide resin in alkali aqueous solution, and is suitable for using as an insulation film in electronic and photoelectric products. The present invention also relates to preparation and use of the above polyimide.
US08722755B2 Photosensitive resin composition and uses thereof
The invention relates to a photosensitive resin composition, and an overcoat and/or spacer for a liquid crystal display component formed thereby has good heat-resistant transmittance, good chemical resistance and good elastic recovery rate. The invention also provides a method for forming a thin film on a substrate, a thin film on a substrate and a liquid crystal display component.
US08722752B2 Polyurethane resin
Disclosed is a polyurethane resin which is obtained by a reaction between a polyisocyanate component, which contains 1,4-bis(isocyanatomethyl)cyclohexane including not less than 80% by mole of trans isomers, and an active hydrogen compound component.
US08722751B2 Thermostable microporous polymethacrylimide foams
The invention relates to compositions for producing polymethacrylimide foams having reduced pore size. The inventive method allows production of a microporous foam with an especially homogeneous pore size distribution without having to use insoluble nucleation agents.
US08722748B2 Process for producing hydrocarbons
In a process for producing hydrocarbons according to the present invention, estimated production rates for a light hydrocarbon oil and a heavy hydrocarbon oil are respectively determined based on a set reaction temperature used when the hydrocarbons are synthesized by a Fischer-Tropsch synthesis reaction, and the discharge flow rates of the light hydrocarbon oil and the heavy hydrocarbon oil from temporary storage buffer tanks (91, 92) during supply to a fractionator (40) are respectively controlled so as to be equal to the respective estimated production rates.
US08722744B2 Galenical form for the administration of paracetamol by transmucous means
A galenical form for the transmucous administration of at least one active ingredient, characterized in that the active ingredient is paracetamol in a stable and complete dissolved state in a hydroalcoholic solution that includes at least 10% by mass of alcohol so as to allow fast absorption of the active ingredient through the mucous membranes of the buccal cavity and/or the oropharynx. A process for production and the uses of the galenical form are also disclosed.
US08722742B2 Chemical compounds having antiviral activity against Dengue virus and other Flaviviruses
Use of chemical compounds obtained in silico for the preparation of pharmaceutical compositions to attenuate or inhibit Dengue virus infection. Particularly, through the interference or the modulation of several stages of viral replication cycle related with the entry of virus into host cells and the assembly of mature progeny virions. The invention also comprises the use of such pharmaceutical compositions for prophylactic and/or therapeutic treatment of infection caused by all four serotypes of Dengue virus and other flaviviruses.
US08722741B2 Biphenyloxyacetic acid derivatives for the treatment of respiratory disease
The invention relates to substituted phenoxyacetic acids of formula (I), where the variables are as defined in claim 1, as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation.
US08722737B2 Compositions comprising polyunsaturated fatty acid monoglycerides, derivatives thereof and uses thereof
There are provided various compounds and compositions comprising polyunsaturated fatty acid monoglycerides and derivatives thereof. These compounds and compositions can be useful as cancer chemopreventive agents. They can also be useful for enhancing solubility of various active agents and enhancing their bioavailability.
US08722736B2 Multi-dose concentrate esmolol with benzyl alcohol
Disclosed are concentrate esmolol injection essentially free from other related esters of esmolol and diluted esmolol compositions. The concentrate esmolol formulation includes from about 25-1000 mg/ml of esmolol and about 1-25% w/v of benzyl alcohol and the combination thereof. The compositions can also be used as multi-dose compositions. The present invention also discloses diluted, ready-to-use compositions of esmolol prepared by dilution of the present invention concentrates. Also disclosed are methods of making and using the ready-to-use compositions of the present invention.
US08722731B2 Furanyl compounds and the use thereof
Provided herein are substituted furanyl compounds of formula (I), pharmaceutical compositions comprising the compounds, methods of their preparation, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or amelioration of various disorders, including cancer and proliferative disorders. In one embodiment, the compounds provided herein modulate eIF4E activity. In one embodiment, the compounds provided herein modulate the Hedgehog pathway activity. In one embodiment, the compounds provided herein are used in combination with surgery, radiation therapy, immuno therapy and/or one or more additional anticancer drugs for the treatment, prevention, and/or amelioration of cancer and proliferative disorders.
US08722730B2 5-membered heterocyclic compound
A compound represented by the following general formula (I): [wherein R1 and R2 represent an alkyl group, X represents —S—, —O— or —NH—, Y represents C or N, R3 represents hydrogen atom or a C1-10 alkyl group, Z represents —CO—N(R5)— (R5 represents hydrogen atom or a C1-6 alkyl group) or —C(R6)═C(R7)—CO—NH— (R6 and R7 represent hydrogen atom or a C1-6 alkyl group), Ar represents an aryldiyl group or a heteroaryldiyl group, and R4 represents —COOH, —OCH2—COOH, —CH2—COOH, or —CH2—CH2—COOH], which has a retinoid action and is useful as an active ingredient of a medicament.
US08722721B2 SEC-hydroxycyclohexyl derivatives
The invention provides novel compounds having the general formula (I) wherein R1, R2 and R3 are as described herein, compositions including the compounds and methods of using the compounds.
US08722718B2 Inhibitors of C-FMS kinase
The invention is directed to compounds of Formula I: wherein Z, X, J, R2 and W are set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase. Methods of treating autoimmune diseases; and diseases with an inflammatory component; treating metastasis from ovarian cancer, uterine cancer, breast cancer, prostate cancer, lung cancer, colon cancer, stomach cancer, hairy cell leukemia; and treating pain, including skeletal pain caused by tumor metastasis or osteoarthritis, or visceral, inflammatory, and neurogenic pain; as well as osteoporosis, Paget's disease, and other diseases in which bone resorption mediates morbidity including rheumatoid arthritis, and other forms of inflammatory arthritis, osteoarthritis, prosthesis failure, osteolytic sarcoma, myeloma, and tumor metastasis to bone with the compounds of Formula I, are also provided.
US08722717B2 3-triazolylphenyl-substituted sulphide derivatives as acaricides and insecticides
The present invention constitutes new 3-triazolylphenyl-substituted sulphide derivatives of the formula (I) in which A1, A2, B0, B1, B2, B3, X, R1, R2 and n are as defined in the description, to their use as acaricides and insecticides for controlling animal pests, and to processes for preparing them.
US08722716B2 Isoxazole treatments for diabetes
The present invention relates to compounds and methods for inducing synthesis and secretion of insulin from pancreatic beta cells. The methods may take place in vitro, ex vivo such as in isolates from adult mammalian tissue, or in vivo. Compounds and methods described herein may find use in the treatment of diabetes.
US08722715B2 Antimicrobial oxazolidinone, hydantoin and imidazolidinone compositions
The present application relates to N-chlorinated oxazolidinone, hydantoin and imidazolidinone compounds of Formula I or pharmaceutically acceptable salts thereof, and associated compositions and methods of use as antimicrobial agents.
US08722713B2 Synergistic antimicrobial composition of 1,2-benzisothiazolin-3-one and tris(hydroxymethyl)nitromethane
A synergistic antimicrobial composition containing 1,2-benzisothiazolin-3-one and tris(hydroxymethyl)nitromethane.
US08722710B2 Deuterium-enriched pioglitazone
The present application describes deuterium-enriched pioglitazone, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.
US08722708B2 Substituted isoindolines as aspartyl protease inhibitors
Disclosed are compounds of the formula I or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein Q is a bond or —N(R5)—; T is a bond, —O—, —C(O)—; S, —N(R5)—, or —C(R6′R7′); U is a bond or —C(R6)(R7)— Y is C or N; Z is C or N; ring A, including variables Y and Z, is a three to nine membered cycloalkyl, cycloalkenyl, heterocyclyl, heterocyclenyl, aryl, and heteroaryl ring having 0 to 4, preferably 0 to 2, heteroatoms independently selected from the group consisting of O, S, N and —N(R)—, wherein ring A is unsubstituted or substituted with 1 to 5 independently selected R1 moieties and/or oxo when ring A is cycloalkyl, cycloalkenyl, heterocyclyl or heterocyclenyl; and R, R1, R2, R3, R4, R5, R6, R6, R7 and R7′ are as defined in the specification; pharmaceutical compositions comprising the compounds of formula I and the method of inhibiting aspartyl protease, and in particular, the methods of treating cardiovascular diseases, cognitive and neurodegenerative diseases.
US08722705B2 Methods for treating diffuse large B-cell lymphoma with 3-(4-amino-1-OXO-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione in combination with second active agents
Methods of treating, preventing and/or managing cancer as well as and diseases and disorders associated with, or characterized by, undesired angiogenesis are disclosed. Specific methods encompass the administration of an immunomodulatory compound alone or in combination with a second active ingredient. The invention further relates to methods of reducing or avoiding adverse side effects associated with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy which comprise the administration of an immunomodulatory compound. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.
US08722702B2 Compounds modulating c-fms and/or c-kit activity and uses therefor
Compounds active on the receptor protein tyrosine kinases c-kit and/or c-fms are provided herewith. Also provided herewith are compositions useful for treatment of c-kit mediated diseases or conditions and/or c-fms-mediated diseases or conditions, and methods for the use thereof.
US08722698B2 Berbamine derivatives
The invention provides novel berbamine derivatives, and compositions or pharmaceutical compositions thereof. These berbamine derivatives have shown higher potency in killing cancer/tumor cells comparing to berbamine, and can be used in cancer/tumor treatments.
US08722695B2 Imidazolidinedione derivatives
The invention provides a compound of formula (Ia), and pharmaceutically acceptable salts thereof. The invention also provides use of the compounds or salts as modulators of Kv3.1 and/or Kv3.2, and in the treatment of diseases or disorders where a modulator of Kv3.1 and/or Kv3.2 is required, such as depression and mood disorders, hearing disorders, schizophrenia, substance abuse disorders, sleep disorders or epilepsy.
US08722687B2 Imidazo [1,2-A]pyridine derivatives as FGFR kinase inhibitors for use in therapy
The invention relates to new bicyclic heterocyclyl derivatives of formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
US08722683B2 Benzodioxole piperazine compounds
The present invention is concerned with novel dual modulators of the 5-HT2A and D3 receptors of formula (I) wherein n, Y, R1, R2, R3, and R4 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions containing them and their use as pharmaceutical agents.
US08722677B2 Viral inhibitors
Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.
US08722676B2 Bicyclic piperazine compounds
Bicyclic piperazine compounds of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
US08722670B2 Selective NR2B antagonists
The disclosure generally relates to compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands, antagonists of the NR2B receptor and may be useful for the treatment of various disorders of the central nervous system.
US08722666B2 Sedative for use during eye surgery
A drug for sedating a patient, and especially a smoker, during eye surgery. The drug includes a sedative such as midazolam in a mix with nicotine. The mixture is injected into the patient prior to the eye surgery.
US08722665B2 Cinnamido-pyrrolo[2,1-C][1,4]benzodiazepines as potential anticancer agents and process for the preparation thereof
The present invention provides a compound of general formulae (8a-i), (11a-i), (14a-i), and (17a-i), useful as potential antitumour agents against human cancer cell lines. The present invention further provides a process for the preparation of Cinnamido-pyrrolo[2,1-c][1,4]benzodiazepines of general formulae (8a-i), (11a-i), (14a-i), and (17a-i).
US08722664B2 Spontaneously dispersible N-benzoyl staurosporine compositions
Spontaneously dispersible N-benzoyl-staurosporine compositions are disclosed for oral administration having high bioavailability levels and reduced variability of bioavailability levels of N-benzoyl-staurosporine, as well as their preparation and use in medical treatment.
US08722660B2 Heterocyclic compound
Provided is a compound useful for the prophylaxis or treatment of cancer.The present invention relates to a compound represented by formula (I): wherein each symbol in the formula is as defined in the specification, or a salt thereof or a prodrug thereof, which is useful for the prophylaxis or treatment of cancer.
US08722657B2 Salts and crystalline forms of an apoptosis-inducing agent
Salts and crystalline forms of 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}-sulfonyl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide are suitable active pharmaceutical ingredients for pharmaceutical compositions useful in treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.
US08722656B2 Cephalosporins useful as antibacterial agents
The present invention provides novel cephalosporin derivatives of formula I, their analogues, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.
US08722654B2 Lipoxin analogs as novel inhibitors of angiogenesis
The present invention is generally drawn to novel isolated therapeutic agents, termed lipoxins, generated from the interaction between a dietary omega-6 polyunsaturated fatty acid (PUFA) such as arachidonic acid (AA), oxygenases and the analgesic aspirin (ASA). Surprisingly, careful isolation of compounds generated from the combination of components in an appropriate environment provide di- and tri-hydroxy containing derivatives of AA containing compounds having unique structural and physiological properties. The present invention therefore provides for many new useful therapeutic di- and tri-hydroxy derivatives of AA (lipoxins, aspirin-triggered epi-lipoxins) that diminish, prevent, or eliminate NV, hemangiogenesis and/or angiogenic condition(s) of corneal tissue. The present invention also provides methods of use, methods of preparation, and packaged pharmaceuticals for use as medicaments for the compounds disclosed throughout the specification.
US08722652B2 Acute treatment of social phobia
Methods and compositions for the treatment of social phobia are provided, including administering a therapeutically effective amount of an androsta-4,16-dien-3-ol steroid to an individual in need of treatment and a pharmaceutical composition for the treatment of social phobia having a therapeutically effective amount of an androsta-4,16-dien-3-ol steroid. Therapeutically effective amounts may be, for example, between about 100 picograms and about 100 micrograms, or between about 1 nanogram and about 10 microgram, or between about 10 nanograms and about 1 microgram of an androsta-4,16-dien-3-ol steroid. Administration of the androsta-4,16-dien-3-ol compound is preferably intranasal administration to the nasal passages and the vomeronasal organ of the individual. A preferred androsta-4,16-dien-3-ol steroid is [3β]-androsta-4,16-dien-3-ol. In some embodiments of the methods, both [3β}-androsta-4,16-dien-3-ol and [3α]-androsta-4,16-dien-3-ol are administered to a patient, and are included in a pharmaceutical composition for the treatment of social phobia.
US08722649B2 Alpha-chloro and alpha-bromo phosphonate analogs of lysophosphatidic acid and methods of making and using thereof
Described herein is the synthesis and pharmacology of a series of α-substituted methylene phosphonate analogs, in which the α-CH2 moiety is replaced with CHCl or CHBr.
US08722647B2 Methods for treating amyloidosis using 4-(amino)-2-(2,6-Dioxo(3-piperidyl))- isoindoline-1,3-dione
Methods of treating, preventing and/or managing cancer as well as and diseases and disorders associated with, or characterized by, undesired angiogenesis are disclosed. Specific methods encompass the administration of an immunomodulatory compound alone or in combination with a second active ingredient. The invention further relates to methods of reducing or avoiding adverse side effects associated with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy which comprise the administration of an immunomodulatory compound. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.
US08722646B2 High concentration chitosan-nucleic acid polyplex compositions
The invention provides highly concentrated chitosan-nucleic acid polyplex compositions and dispersions, and methods for producing the compositions and dispersions. Methods of mixing the chitosan-nucleic acid polyplexes include an inline mixing of chitosan solution and nucleic acid solution, followed by further concentrating the dispersion of chitosan-nucleic acid polyplexes, optionally with an aggregation inhibitor. Further provided are methods for altering the diameter of chitosan-nucleic acid polyplexes.
US08722643B2 Targeting EN2, PAX2, and/or DEFB1 for treatment of prostate conditions
The present invention relates to methods and compositions for treating a prostate condition in a subject. The method comprises administering to the subject a subject effective amount of a pharmaceutical composition having a first agent that inhibits EN2 expression and/or EN2 activity and a second agent that inhibits PAX2 expression and/or PAX2 activity. The pharmaceutical composition may further comprise a third agent that enhances DEFB1 expression or activity.
US08722642B2 Multiantivirus compound, composition and method for treatment of virus diseases
A method for obtaining a new antiviral compound with multiple action against many viruses, comprising modified highly purified yeast RNA, a pharmaceutical composition comprising such RNA, and a method for the treatment and prevention of viral disease comprising administering to a patient a composition comprising an amount effective to ameliorate the symptoms of viral disease of ribonucleic acid. The exogenous modified yeast RNA has a pronounced multiple anti-virus action in a wide range of concentrations. The modified yeast RNA is capable of inhibiting the reproduction of viruses from Orthomyxoviridae, Paramyxovirus, Hepatitis, Herpesviridae families, enterovirus and adenovirus. Also, the modified yeast RNA is capable of inhibiting the reproduction of influenza viruses, hepatitis C virus, genital herpes, human immunodeficiency virus and Coxsackie B virus.
US08722639B2 Means and methods for the treatment of hearing loss and phantom hearing
This invention relates to modulators of NADPH oxidase as a medicament for the treatment and/or prevention of hearing loss and/or phantom hearing. Such modulators preferably act by inhibiting NADPH oxidase activity, wherein the NADPH oxidase comprises or consists of the amino acid sequence of any one of SEQ ID NO: 1, 3 or 5, or (ii) is encoded by a nucleic acid comprising or consisting of the sequence of any one of SEQ ID NO: 2, 4, 6, 23 or 24, or (iii) is a fragment of the protein according to (i) or (ii) and exhibits NADPH oxidase activity, or (iv) has a sequence at least 75% identical with the protein according to (i) or (ii) or with the fragment according to (iii) and exhibits NADPH oxidase activity. Also provided are pharmaceutical compositions, medical uses and diagnostic uses of compounds of the invention.
US08722633B2 Glycoside derivatives and uses thereof
The present invention provides a compound of formula I; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
US08722626B2 Method for controlling fibrosis and other pathological deposits in tissues comprising administering a GHRP-6 composition
The present invention is related to the use of secretagogue peptides repeatedly administered as part of a pharmaceutical composition that prevent and eradicate the deposition of pathological fibrotic material in parenchymal tissues of internal organs like the liver, lungs, esophagus, small intestine, kidneys, blood vessels, joints, and other systemic forms of cutaneous fibrosis of any etiopathogenesis. Additionally, these peptides prevent and eradicate deposition of amiloid and hyaline materials in any of their correspondent chemical forms and tissue manifestations in the brain, cerebellum, blood vessels, liver, intestines, kidneys, spleen, pancreas, joints and the skin, among others. By this way, cellular, tissular and organ dysfunctions generated by these depositions are corrected. The peptides of the present invention are infiltrated or topically applied, contributing to prevent and eradicate keloids and hypertrophic scars in the skin, derived as sequelae of burns and other cutaneous trauma.
US08722617B2 Mussel adhesive protein derived vectors for gene delivery
The present invention is related to a composition and a method for delivering a nucleic acid into a cell. The invention also provides a biocompatible and biodegradable gene delivery composition and methods of use and making thereof.
US08722615B2 Compositions and methods for increasing serum half-life
Provided herein are glycovariant Fc fusion proteins having increased serum half lives. Also provided are methods for increasing the serum half life of an Fc fusion protein by introducing one or more non-endogenous glycosylation sites.
US08722602B2 Grease
Grease which includes a base oil containing at least 50% by mass of a specific diester compound of a glycol with a branched carboxylic acid, and a specific diurea compound as a thickener. The grease is excellent in low-temperature performance and has low oil separation tendency. In particular, when used in a rotation transmission device having a built-in one-way clutch, the grease can provide satisfactory clutch engagement performance (intermeshing) at low temperatures and is less apt to cause oil separation under high centrifugal force.
US08722600B2 Polymers with H-bridge forming functionalities for improving anti-wear protection
The invention relates to lubricating oil formulations comprising copolymers or graft copolymers produced by radically polymerising polymerisable monomers and, in addition comprising long-chain ethylenically unsaturated compounds containing alkyl, in particular acrylate or methacrylate substitutes provided with hydrogen-bridge donator functions. The monomer exhibiting a hydrogen-bridge donator property is contained, according to said invention, in the polymer backbone or in graft side branches. Apart from the polymers containing monomers provided with hydrogen-bridge donator functions, said invention relates to polymers containing monomers simultaneously carrying donator and acceptor functions. It was found that the hydrogen-bridge donator functions of a polymer, in particular a simultaneous availability of the hydrogen-bridge donator and acceptor functions produce the positive effects on the anti-wear protection and on a detergency and dispersancy action. The inventive polymers are suitable, in the form of additives, for lubricating oil formulations, for example for motor oils or hydraulic fluids exhibiting an improved anti-wear behavior.
US08722599B2 Lubricating compositions containing an antiwear agent
The invention provides a lubricating composition containing an oil of lubricating viscosity and a compound obtained/obtainable by a process comprising reacting a glycolic acid, a 2-halo-acetic acid, or a lactic acid, or an alkali or alkaline metal salts thereof, (typically glycolic acid or a 2-halo-acetic acid) with at least one member selected from the group consisting of an amine, an alcohol, and an aminoalcohol. The invention further relates to the use of the lubricating composition in an internal combustion engine.
US08722597B2 Lubricating oil composition for internal combustion engine
Provided is a lubricating oil composition for an internal combustion engine, including as essential components the following component (A), component (B), and component (C), in which a phosphorus content of the composition is 50 ppm by mass to 1,000 ppm by mass: Component (A): a base oil; Component (B): a compound represented by the following general formula (1); and Component (C): a metal-containing antioxidant: where R1 to R8 each independently represent a hydrogen atom or an alkyl group having 1 to 20 carbon atoms, Z represents a hydrocarbon group having 2 to 20 carbon atoms, and n represents a number of 1 to 10.
US08722595B2 Lubricating oil compositions
The present invention provides a lubricating oil composition capable of achieving a lubricating property, a thermal stability, an oxidation stability, an anti-discoloring property and an anti-varnishing performance with a higher level by compounding a phosphorus compound having a specific structure in a base oil, as well as a lubricating oil composition for internal combustion engines which is excellent in wear resistance, high-temperature detergency and base number retention property although it has a low phosphorus content, a low sulfur content and a low sulfated ash content.
US08722593B2 Alkoxylated thiacalixarenes and the use thereof as crude oil demulsifiers
The invention relates to compounds with the formula (II), where R is a C1- to C30-alkyl group, a C2- to C30-alkenyl group, a C6- to C18-aryl group, or a C7- to C30-alkylaryl group, AO is a C2-C4-alkoxy group, x is a number from 1 to 50, m is a number between 4 and 12, and to the use thereof in quantities of 0.0001 to 5% by weight relative to the oil content of the emulsion to be demulsified, for splitting water in oil emulsions.
US08722590B2 Ceramic proppants
A sintered, generally spherical ceramic body, having an alumina content of from about 52 to about 58 weight percent distributed substantially homogeneously throughout the body, a silica content from about 32 to about 39 weight percent distributed substantially homogeneously throughout the body, an apparent specific gravity of about 2.63 to about 2.67, and a bulk density of about 1.48 to about 1.56 grams per cubic centimeter.
US08722584B2 Genetic selection for protein folding and solubility in the bacterial periplasm
The present invention relates to the fields of microbiology, molecular biology and protein biochemistry. More particularly, it relates to compositions and methods for analyzing and altering (e.g., enhancing or inhibiting) protein folding and solubility (e.g., within periplasm). The present invention provides an engineered assay for protein folding and solubility in the E. coli periplasm based on co-translational translocation of a chimera comprising a protein of interest fused to TEM-I β-lactamase that is targeted for export via the signal recognition particle (SRP)-dependent pathway. Using an array of native and heterologous proteins, it is demonstrated that periplasmic folding behavior of proteins is intimately coupled to in vivo β-lactamase activity. As a result of this coupling, the reporter is useful for (1) facile discovery of extrinsic periplasmic factors that affect protein folding and solubility; and (2) genetic selection of solubility-enhanced proteins.
US08722580B2 Agent for inhibiting cytokinin signaling
Disclosed are: a substance which has an activity of inhibiting the intracellular signaling from a plant-derived cytokinin receptor and which can control the growth or differentiation of a plant. Also, disclose is a method for searching for a chemical substance capable of promoting the growth of a root of a plant, which comprises measuring the level of intracellular signaling from the receptor in a system where a cell having the receptor is contacted with a chemical substance having an agonistic activity on the receptor and a substance to be tested, comparing the level of intracellular signaling measured in the preceding step with a level of intracellular signaling measured in the absence of the chemical substance, and determining the chemical substance as being a chemical substance capable of promoting the growth of a root of a plant based on the difference obtained by the comparison; and others.
US08722579B2 Biocidal composition for treating water
An aqueous composition for treatment of water comprising: (a) an N,N-dimethyl-2-hydroxypropylammonium chloride polymer; (b) lanthanum chloride; and (c) a dimethylamine epichlorohydrin ethylenediamine polymer; and a method of treating water using the composition.
US08722577B2 Plant health composition
The present invention relates to a composition containing (A) at least one specific carbamate fungicide, (B) at least one specific insecticide and optionally (C) at least one azole, the use of this composition for improving plant health and a method for improving plant health by treating a plant, its propagules or the locus where the plant is growing or is to grow with the above composition.
US08722575B2 Packaging material with a coloured element which at a predetermined temperature discolours partially, revealing a marking, and method for producing this material
It is disclosed a packaging material (1) for a pharmaceutical product. The packaging material comprises a colored element (2) which at a predetermined temperature, below which the pharmaceutical product must be kept, discolors partially, revealing a marking. The element is formed by a first portion forming the marking (2′) printed with conventional ink, and a second portion (2″) printed with thermochromic ink. The thermochromic ink is colored below the predetermined temperature and becomes colorless when this predetermined temperature is reached or exceeded. The two portions are arranged so that the first portion is invisible below the predetermined temperature, but becomes visible when this temperature is reached or exceeded.
US08722573B2 Sulfonated carbon silica composite material and a process for the preparation thereof
The present invention relates to a novel sulfonated carbon silica (SCS) composite material and a process for the preparation thereof. The synthesized SCS composite material on calcination yields the hierarchical mesoporous silica (MS) and further finds application as catalyst in two industrially important reactions namely phenol butylation and glycerol acetalization.
US08722570B2 Cobalt catalyst with improved activity maintenance
The present invention provides a catalyst comprising a catalytic metal, preferably cobalt, rhenium or mixtures thereof. The catalytic metal is supported on a support comprising a major amount of titania and a minor amount of cobalt aluminate derived from anatase titania. The support also includes a minor amount of titania derived from a titanium chelate.
US08722569B2 Peroxide decomposition catalyst particles
A catalytically active component is provided which comprises particles containing a metal oxide such as silica, metal or metalloid ions such as ions that include boron, and a catalyst. When introduced into the membrane electrode assembly of a fuel cell, the particles increase peroxide radical resistance in a membrane electrode.
US08722564B2 Hydroprocessing catalysts and their production
Described herein is a catalyst precursor composition comprising at least one metal from Group 6 of the Periodic Table of the Elements, at least one metal from Groups 8-10 of the Periodic Table of the Elements, and a reaction product formed from (i) a first organic compound containing at least one amine group and at least 10 carbon atoms or (ii) a second organic compound containing at least one carboxylic acid group and at least 10 carbon atoms, but not both, wherein the reaction product contains additional unsaturated carbon atoms, relative to the first or second organic compound, wherein the metals of the catalyst precursor composition are arranged in a crystal lattice, and wherein the reaction product is not located within the crystal lattice. A process for preparing the catalyst precursor composition is also described, as is sulfiding the catalyst precursor composition to form a hydroprocessing catalyst.
US08722563B2 Hydroprocessing catalysts and their production
Described herein is a catalyst precursor composition comprising at least one metal from Group 6 of the Periodic Table of the Elements, at least one metal from Groups 8-10 of the Periodic Table of the Elements, and a reaction product formed from (i) a first organic compound containing at least one amine group, and (ii) a second organic compound separate from said first organic compound and containing at least one carboxylic acid group. A process for preparing the catalyst precursor composition is also described, as is sulfiding the bulk mixed metal oxide catalyst precursor composition to form a hydroprocessing catalyst.
US08722561B2 Diethylzinc composition, method for heat stabilization, and compound for heat stabilization
[Object]To improve heat stability of diethylzinc which is used for a catalyst of polymerizing, an organic synthetic reaction reagent and a raw materials for providing a zinc film by MOCVD. And to offer the diethylzinc composition being superior in heat stability, even if it handles for a long term a metal zinc particle does not precipitate.[Solving Means]Use a diethylzinc composition added a compound which is added an aromatic compound as an additive which has isopropenyl group bonded as a side chain.
US08722560B2 Highly heat-resistant β-type zeolite and SCR catalyst employing the same
A subject for the invention is to provide a highly heat-resistant SCR catalyst which has an NOx reduction percentage of 40% or higher at 200° C. after a hydrothermal durability treatment. The invention relates to use of β-type zeolite which has an SiO2/Al2O3 molar ratio of 20 or higher but less than 30 and a crystallite diameter before a hydrothermal durability treatment of 20 nm or larger, shows a change in crystallite through the hydrothermal durability treatment of less than 10%, and has a fluorine content lower than 0.1%. The β-type zeolite can be crystallized from a liquid reaction mixture containing a secondary and/or a tertiary alkylamine having 5 or more carbon atoms.
US08722558B2 Process for producing regenerated hydrotreating catalyst and process for producing petrochemical product
Provided is a process for producing a regenerated hydrotreating catalyst by regenerating a spent hydrotreating catalyst in a prescribed temperature range, wherein the prescribed temperature range is a temperature range of T1−30° C. or more and T2+30° C. or less, as determined by subjecting the spent hydrotreating catalyst to a differential thermal analysis, converting a differential heat in a measuring temperature range of 100° C. or more and 600° C. or less to a difference in electromotive force, differentiating the converted value twice by temperature to provide a smallest extreme value and a second smallest extreme value, and representing a temperature corresponding to the extreme value on the lower-temperature side as T1 and a temperature corresponding to the extreme value on the higher-temperature side as T2.
US08722557B2 Catalyst regeneration
A method is disclosed for regenerating a used catalyst mixture comprising (i) an isomerization catalyst comprising magnesium oxide and (ii) a metathesis catalyst comprising an inorganic carrier and at least one of molybdenum oxide and tungsten oxide. The method comprises (a) decoking the used catalyst mixture in the presence of an oxygen-containing gas to produce a decoked catalyst mixture; and (b) contacting the decoked catalyst mixture with steam at a temperature in the range of 100 to 300° C. to produce a regenerated catalyst mixture.
US08722555B2 High-strength transparent zirconia sintered body, process for producing the same, and uses thereof
Translucent zirconia sintered bodies have had a problem that incorporation of titania improves translucency but lowers mechanical strength. The invention provides: a zirconia sintered body containing titanium oxide, the sintered body containing 6-15 mol % yttria and 3-20 mol % titania and having an in-line transmission of 50% or higher when examined at a sample thickness of 1 mm and a measuring wavelength of 600 nm; and a zirconia sintered body having especially high translucency which is a high-quality transparent zirconia sintered body that contains 3-20 mol % titania and 6-15 mol % yttria and has an in-line transmission, as measured at a wavelength of 600 nm, of 73% or higher and a haze value of 2.0% or less and that is highly translucent and is undimmed (cloudless). The invention further relates to a production process in which a powder having the composition is molded and thereafter subjected to ordinary-pressure primary sintering and hot isostatic pressing (HIP) under specific conditions.
US08722547B2 Etching high K dielectrics with high selectivity to oxide containing layers at elevated temperatures with BC13 based etch chemistries
Wafers having a high K dielectric layer and an oxide or nitride containing layer are etched in an inductively coupled plasma processing chamber by applying a source power to generate an inductively coupled plasma, introducing into the chamber a gas including BCl3, setting the temperature of the wafer to be between 100° C. and 350° C., and etching the wafer with a selectivity of high K dielectric to oxide or nitride greater than 10:1. Wafers having an oxide layer and a nitride layer are etched in a reactive ion etch processing chamber by applying a bias power to the wafer, introducing into the chamber a gas including BCl3, setting the temperature of the wafer to be between 20° C. and 200° C., and etching the wafer with an oxide to nitride selectivity greater than 10:1. Wafers having an oxide layer and a nitride layer are etched in a an inductively coupled plasma processing chamber by applying a bias power to the wafer, applying a source power to generate an inductively coupled plasma, introducing into the chamber a gas including BCl3, setting the temperature of the wafer to be between 20° C. and 200° C., and etching the wafer with an oxide to nitride selectivity greater than 10:1.
US08722545B2 Method of selectively deglazing P205
A method of forming a transistor is disclosed, in which gate-to-substrate leakage is addressed by forming and maintaining a conformal oxide layer overlying the transistor gate. Using the method disclosed for an n-type device, the conformal oxide layer can be formed as part of the source-drain doping process. Subsequent removal of residual phosphorous dopants from the surface of the oxide layer is accomplished without significant erosion of the oxide layer. The removal step uses a selective deglazing process that employs a hydrolytic reaction, and an acid-base neutralization reaction that includes an ammonium hydroxide component.
US08722543B2 Composite hard mask with upper sacrificial dielectric layer for the patterning and etching of nanometer size MRAM devices
A composite hard mask is disclosed that prevents build up of metal etch residue in a MRAM device during etch processes that define an MTJ shape. As a result, MTJ shape integrity is substantially improved. The hard mask has a lower non-magnetic spacer, a middle conductive layer, and an upper sacrificial dielectric layer. The non-magnetic spacer serves as an etch stop during a pattern transfer with fluorocarbon plasma through the conductive layer. A photoresist pattern is transferred through the dielectric layer with a first fluorocarbon etch. Then the photoresist is removed and a second fluorocarbon etch transfers the pattern through the conductive layer. The dielectric layer protects the top surface of the conductive layer during the second fluorocarbon etch and during a substantial portion of a third RIE step with a gas comprised of C, H, and O that transfers the pattern through the underlying MTJ layers.
US08722540B2 Controlling defects in thin wafer handling
A method includes bonding a wafer on a carrier through an adhesive, and performing a thinning process on the wafer. After the step of performing the thinning process, a portion of the adhesive not covered by the wafer is removed, while the portion of the adhesive covered by the wafer is not removed.
US08722538B2 Method for forming contact window
A method for forming a contact window includes: a step of providing a substrate; a step of forming a patterned amorphous carbon layer or spin-on coating layer, in which a surface of the substrate is exposed at two sides of the amorphous carbon layer or spin-on coating layer; a step of forming an interlayer dielectric layer on the substrate; a step of removing a portion of the interlayer dielectric layer until the patterned amorphous carbon layer or spin-on coating layer is exposed; a step of removing the patterned amorphous carbon layer or spin-on coating layer to form an opening; and a step of filling the opening with a conductive material to form the contact window.
US08722535B2 Pattern forming method, mold and data processing method
According to one embodiment, a pattern forming method is disclosed. The method can include forming an insulating layer on a major surface of a substrate. The method can include forming first and second openings on the insulating layer. The first opening has a first length in a first direction along the major surface, and the second opening has a second length longer than the first length in the first direction. The method can include forming a first pattern in the first opening. The method can include forming a second pattern in the second opening. The method can include forming a self-assembled material film contacting the insulating layer, the first pattern and the second pattern. The method can include forming a third pattern with guidance of the second pattern. In addition, the method can include forming a fourth pattern contacting the first pattern based on the third pattern.
US08722532B2 Semiconductor device and a method for manufacturing a semiconductor device
A first wiring is disposed over a semiconductor substrate. A first via is disposed over the first wiring. Further, the bottom surface of the first via is in contact with the first wiring. A first insulation layer is disposed over the semiconductor substrate, and is in contact with at least the top surface of the first wiring and the side surface of the first via. At least a part of each side surface of the first wiring and the first via cuts off each metal crystal grain.
US08722528B2 Die backside standoff structures for semiconductor devices
Standoff structures that can be used on the die backside of semiconductor devices and methods for making the same are described. The devices contain a silicon substrate with an integrated circuit on the front side of the substrate and a backmetal layer on the backside of the substrate. Standoff structures made of Cu of Ni are formed on the backmetal layer and are embedded in a Sn-containing layer that covers the backmetal layer and the standoff structures. The standoff structures can be isolated from each other so that they are not connected and can also be configured to substantially mirror indentations in the leadframe that is attached to the Sn-containing layer. Other embodiments are described.
US08722526B2 Growing of gallium-nitrade layer on silicon substrate
Embodiments relate to growing an epitaxy gallium-nitride (GaN) layer on a porous silicon (Si) substrate. The porous Si substrate has a larger surface area compared to non-porous Si substrate to distribute and accommodate stress caused by materials deposited on the substrate. An interface adjustment layer (e.g., transition metal silicide layer) is formed on the porous silicon substrate to promote growth of a buffer layer. A buffer layer formed for GaN layer may then be formed on the silicon substrate. A seed-layer for epitaxial growth of GaN layer is then formed on the buffer layer.
US08722524B2 Method for forming a semiconductor device including replacing material of dummy gate stacks with other conductive material
It is provided a method for forming a semiconductor device comprising: forming a material layer which exposes dummy gates and sidewall spacers and fills spaces between two adjacent gate stacks, and the material of the material layer is the same as the material of the dummy gate; removing the dummy gates and the material layer to form recesses; filling the recesses with a conductive material, and planarizing the conductive material to expose the sidewall spacers; breaking the conductive material outside the sidewall spacers to form at least two conductors, each of the conductors being only in contact with the active region at one side outside one of the sidewall spacers, so as to form gate stack structures and first contacts. Besides, a semiconductor device is provided. The method and the semiconductor device are favorable for extending process windows in forming contacts.
US08722521B2 Method of laser irradiation, laser irradiation apparatus, and method of manufacturing a semiconductor device
If an optical path length of an optical system is reduced and a length of a laser light on an irradiation surface is increased, there occurs curvature of field which is a phenomenon that a convergent position deviates depending on an incident angle or incident position of a laser light with respect to a lens. To avoid this phenomenon, an optical element having a negative power such as a concave lens or a concave cylindrical lens is inserted to regulate the optical path length of the laser light and a convergent position is made coincident with a irradiation surface to form an image on the irradiation surface.
US08722517B2 Dicing tape-integrated film for semiconductor back surface
The present invention provides a dicing tape-integrated film for semiconductor back surface, including a film for flip chip type semiconductor back surface for protecting a back surface of a semiconductor element flip chip-connected onto an adherend, and a dicing tape, the dicing tape including a base material and a pressure-sensitive adhesive layer provided on the base material, the film for flip chip type semiconductor back surface being formed on the pressure-sensitive adhesive layer, in which the pressure-sensitive adhesive layer is a radiation-curable pressure-sensitive adhesive layer whose pressure-sensitive adhesive force toward the film for flip chip type semiconductor back surface is decreased by irradiation with a radiation ray.
US08722515B2 Process of treating defects during the bonding of wafers
The invention concerns a process of preparing a thin layer to be transferred onto a substrate having a surface topology and, therefore, variations in altitude or level, in a direction perpendicular to a plane defined by the thin layer, this process comprising the formation on the thin layer of a layer of adhesive material, the thickness of which enables carrying out a plurality of polishing steps of its surface in order to eliminate any defect or void or almost any defect or void, in preparation for an assembly via a molecular kind of bonding with the substrate.
US08722512B2 Method of manufacturing semiconductor device with a dummy layer
The invention enhances the accuracy of an end point detection when an insulation film formed on a semiconductor substrate is dry-etched. Gate layers made of polysilicon are formed, and an end point detection dummy layer made of polysilicon is formed on a LOCOS. After the gate layers and the dummy layer are formed, a TEOS film is formed on a silicon substrate so as to cover the gate layers and the dummy layer. The TEOS film, a thin gate oxide film and a thick gate oxide film are then dry-etched to form sidewalls on the sidewalls of the gate layers and also expose the front surface of the P well of the silicon substrate in a region surrounded by the LOCOS. The end point detection dummy layer helps the end point detection by being exposed during this dry-etching to enhance the accuracy of the end point detection.
US08722502B2 Chip-stacked semiconductor device and manufacturing method thereof
A method of manufacturing a semiconductor device, includes forming a trench surrounding a first area of a semiconductor substrate, the trench having a bottom surface and two side surfaces being opposite to each other, forming a silicon film on the bottom surface and side surfaces of the trench, forming an insulation film on the silicon film in the trench, grinding a bottom surface of the semiconductor substrate to expose the insulation film formed over the bottom surface of the trench, and forming a through electrode in the first area after grinding the bottom surface of the semiconductor substrate, the through electrode penetrating the semiconductor substrate.
US08722499B2 Method for fabricating a field effect device with weak junction capacitance
The field effect device is formed on a substrate of semiconductor on insulator type provided with a support substrate separated from a semiconductor film by an electrically insulating layer. The source and drain electrodes are formed in the semiconductor film on each side of the gate electrode. The electrically insulating layer comprises a first area having a first electric capacitance value between the semiconductor film and the support substrate facing the gate electrode. The electrically insulating layer comprises second and third areas having a higher electric capacitance value than the first value between the semiconductor film and the support substrate facing the source and drain electrodes.
US08722497B2 Silicon carbide semiconductor device and method for producing the same
A silicon carbide semiconductor device (90), includes: 1) a silicon carbide substrate (1); 2) a gate electrode (7) made of polycrystalline silicon; and 3) an ONO insulating film (9) sandwiched between the silicon carbide substrate (1) and the gate electrode (7) to thereby form a gate structure, the ONO insulating film (9) including the followings formed sequentially from the silicon carbide substrate (1): a) a first oxide silicon film (O) (10), b) an SiN film (N) (11), and c) an SiN thermally-oxidized film (O) (12, 12a, 12b). Nitrogen is included in at least one of the following places: i) in the first oxide silicon film (O) (10) and in a vicinity of the silicon carbide substrate (1), and ii) in an interface between the silicon carbide substrate (1) and the first oxide silicon film (O) (10).
US08722496B1 Method for making embedded cost-efficient SONOS non-volatile memory
A cost-efficient SONOS (CEONOS) non-volatile memory (NVM) cell production method for CMOS ICs, where the CEONOS NVM cell requires two or three additional masks, but can otherwise be formed using the same standard CMOS flow processes used to form NMOS transistors. A first additional mask is used to form an oxide-nitride-oxide (ONO) layer that replaces the standard NMOS gate oxide and serves to store NVM data (i.e., trapped charges). A second additional mask is used to perform drain engineering, including a special pocket implant and LDD extensions, which facilitates program/erase of the CEONOS NVM cells using low voltages (e.g., 5V). The polysilicon gate, source/drain contacts and metallization are formed using corresponding NMOS processes. The CEONOS NVM cells are arranged in a space-efficient X-array pattern such that each group of four cells share three bit lines. Programming involves standard CHE injection or pulse agitated interface substrate hot electron injection (PAISHEI).
US08722495B2 Semiconductor structures employing strained material layers with defined impurity gradients and methods for fabricating same
Semiconductor structures and devices including strained material layers having impurity-free zones, and methods for fabricating same. Certain regions of the strained material layers are kept free of impurities that can interdiffuse from adjacent portions of the semiconductor. When impurities are present in certain regions of the strained material layers, there is degradation in device performance. By employing semiconductor structures and devices (e.g., field effect transistors or “FETs”) that have the features described, or are fabricated in accordance with the steps described, device operation is enhanced.
US08722492B2 Nanowire pin tunnel field effect devices
A method for forming a nanowire tunnel device includes forming a nanowire suspended by a first pad region and a second pad region over a semiconductor substrate, forming a gate structure around a channel region of the nanowire, implanting a first type of ions at a first oblique angle in a first portion of the nanowire and the first pad region, and implanting a second type of ions at a second oblique angle in a second portion of the nanowire and the second pad region.
US08722489B2 Method of fabricating non-volatile memory device
A method of fabricating a non-volatile memory is provided. A tunneling dielectric layer and a first patterned conductive layer are sequentially formed on a substrate. A patterned inter-gate dielectric layer and a second patterned conductive layer are stacked on a first surface of the first patterned conductive layer, and a second surface of the first patterned conductive layer is exposed. The second surface is adjacent to the first surface. The substrate is covered by a passivation layer, and a first sidewall of the first patterned conductive layer is exposed. A recess is formed on the first sidewall of the first patterned conductive layer, such that the first sidewall has a sharp corner. A portion of the passivation layer on the second surface is removed, such that the sharp corner of the first patterned conductive layer is exposed.
US08722488B2 Method of fabricating semiconductor device
A method of fabricating a semiconductor device includes the following steps. At first, two gate stack layers are formed on a semiconductor substrate, and a material layer covering the gate stack layers is formed on the semiconductor substrate. Subsequently, a part of the material layer is removed to form a sacrificial layer between the gate stack layers, and a spacer at the opposite lateral sides of the gate stack layers. Furthermore, a patterned mask covering the gate stack layers and the spacer and exposing the sacrificial layer is formed, and the sacrificial layer is removed.
US08722485B1 Integrated circuits having replacement gate structures and methods for fabricating the same
A method of fabricating an integrated circuit includes the steps of providing a semiconductor substrate having formed thereon a sacrificial silicon oxide layer, an interlayer dielectric layer formed over the sacrificial silicon oxide layer, and a dummy gate structure formed over the sacrificial silicon oxide layer and within the interlayer dielectric layer, removing the dummy gate structure to form an opening within the interlayer dielectric layer, and removing the sacrificial silicon oxide layer within the opening to expose the semiconductor substrate within the opening. The method further includes the steps of thermally forming an oxide layer on the exposed semiconductor substrate within the opening, subjecting the thermally formed oxide layer to a decoupled plasma oxidation treatment, and etching the thermally formed oxide layer using a self-saturated wet etch chemistry. Still further, the method includes depositing a high-k dielectric over the thermally formed oxide layer within the opening.
US08722480B2 Transistors having argon gate implants and methods of forming the same
Transistors are provided including first and second source/drain regions, a channel region and a gate stack having a first gate dielectric over a substrate, the first gate dielectric having a dielectric constant higher than a dielectric constant of silicon dioxide, and a metal material in contact with the first gate dielectric, the metal material being doped with an inert element. Integrated circuits including the transistors and methods of forming the transistors are also provided.
US08722479B2 Method of protecting STI structures from erosion during processing operations
Generally, the present disclosure is directed to a method of at least reducing unwanted erosion of isolation structures of a semiconductor device during fabrication. One illustrative method disclosed includes forming an isolation structure in a semiconducting substrate and forming a conductive protection ring above plurality isolation structure.
US08722476B2 Compound semiconductor device and manufacture process thereof
A compound semiconductor device includes a compound semiconductor layer, a gate electrode disposed above the compound semiconductor layer, and a gate insulation film. The gate insulation film is interposed between the compound semiconductor layer and the gate electrode. The gate insulation film contains a fluorine compound at least in the vicinity of the interface with the compound semiconductor layer.
US08722474B2 Semiconductor device including stepped gate electrode and fabrication method thereof
Disclosed are a semiconductor device including a stepped gate electrode and a method of fabricating the semiconductor device. The semiconductor device according to an exemplary embodiment of the present disclosure includes: a semiconductor substrate having a structure including a plurality of epitaxial layers and including an under-cut region formed in a part of a Schottky layer in an upper most part thereof; a cap layer, a first nitride layer and a second nitride layer sequentially formed on the semiconductor substrate to form a stepped gate insulating layer pattern; and a stepped gate electrode formed by depositing a heat-resistant metal through the gate insulating layer pattern, wherein the under-cut region includes an air-cavity formed between the gate electrode and the Schottky layer.
US08722467B2 Method of using bonding ball array as height keeper and paste holder in semiconductor device package
A die attach method for a semiconductor chip with a back metal layer located at the back surface of the semiconductor chip comprises the steps of forming a bonding ball array including a plurality of bonding balls with a same height on a die attach area at a top surface of a die paddle; depositing a die attach material in the bonding ball array area with a thickness of the die attach material equal or slightly larger than the height of the bonding ball; attaching the semiconductor chip to the die attach area at the top surface of the die paddle by the die attach material, wherein the bonding ball array controls the bond line thickness of the die attach material between the back metal layer and the top surface of the die paddle and prevents the semiconductor chip from rotating on the die attach material when it is melted.
US08722465B1 Method of assembling semiconductor device including insulating substrate and heat sink
Semiconductor dies are mounted on a heat sink array frame structure. The heat sink array frame structure and the semiconductor dies are assembled together with an insulating substrate that has a corresponding array of apertures on an adhesive tape. The semiconductor dies are connected electrically with electrical contacts on the insulating substrate. The semiconductor dies, heat sinks and electrical connections to the contacts are encapsulated with a mold compound and then the encapsulated array is de-taped and singulated.
US08722463B2 Chip package and fabrication method thereof
The invention is related to a chip package including: a semiconductor substrate having at least one bonding pad region and at least one device region, wherein the semiconductor substrate includes a plurality of heavily doped regions in the bonding pad region, and two of the heavily doped regions are insulatively isolated; a plurality of conductive pad structures disposed over the bonding pad region; at least one opening disposed at a sidewall of the chip package to expose the heavily doped regions; and a conductive pattern disposed in the opening to electrically contact with the heavily doped region.
US08722462B2 Semiconductor package
A method of manufacturing a semiconductor package includes providing a carrier and attaching at least one semiconductor piece to the carrier. An encapsulant is deposited onto the at least one semiconductor piece to form an encapsulated semiconductor arrangement. The encapsulated semiconductor arrangement is then singulated in at least two semiconductor packages, wherein each package includes a semiconductor die separated from the semiconductor piece during singulation.
US08722459B2 Methods of forming 3-D circuits with integrated passive devices
Methods of forming 3-D ICs with integrated passive devices (IPDs) include stacking separately prefabricated substrates coupled by through-substrate-vias (TSVs). An active device (AD) substrate has contacts on its upper portion. An isolator substrate is bonded to the AD substrate so that TSVs in the isolator substrate are coupled to the contacts on the AD substrate. An IPD substrate is bonded to the isolator substrate so that TSVs therein are coupled to an interconnect zone on the isolator substrate and/or TSVs therein. The IPDs of the IPD substrate are coupled by TSVs in the IPD and isolator substrates to devices in the AD substrate. The isolator substrate provides superior IPD to AD cross-talk attenuation while permitting each substrate to have small high aspect ratio TSVs, thus facilitating high circuit packing density and efficient manufacturing.
US08722450B1 Method for manufacturing improved solar cell module
The present invention generally relates to a method for manufacturing an improved solar cell module, more particularly to a method for manufacturing the improved solar cell module that may not happen problems of power leakage and short circuit and save the cost to manufacturing.
US08722446B2 Acoustic sensor and method of manufacturing the same
Provided is an acoustic sensor. The acoustic sensor includes: a substrate including sidewall portions and a bottom portion extending from a bottom of the sidewall portions; a lower electrode fixed at the substrate and including a concave portion and a convex portion, the concave portion including a first hole on a middle region of the bottom, the convex portion including a second hole on an edge region of the bottom; diaphragms facing the concave portion of the lower electrode, with a vibration space therebetween; diaphragm supporters provided on the lower electrode at a side of the diaphragm and having a top surface having the same height as the diaphragm; and an acoustic chamber provided in a space between the bottom portion and the sidewall portions below the lower electrode.
US08722444B1 Microelectromechanical system having movable element integrated into substrate-based package
A method of fabricating a MEMS device is disclosed. A metal layer is provided over a first surface of a substrate including over an opening. The metal layer is patterned to define a membrane segment and a pad, with the membrane segment extending at least partially across the opening. An integrated circuit chip is attached over the opening to the membrane segment and pad, with the integrated circuit separated from an extending portion of the membrane segment by a gap. The integrated circuit chip includes a conductive member so that deflection of the extending portion relative to the conductive member can be measured as a change in capacitance.
US08722440B2 Display substrate and method of manufacturing the same
A display substrate includes a gate electrode, a gate insulating layer, and a semiconductor layer that are sequentially formed on a substrate. Also, the display substrate includes a color filter layer formed on the substrate and exposing a portion of the semiconductor layer, and source and drain electrodes that each overlap with the semiconductor layer and the color filter layer. The gate electrode, the gate insulating layer, and the semiconductor layer have the same shape as each other, and the gate electrode is insulated from the gate insulating layer and the semiconductor layer by the color filter layer.
US08722437B2 Method of component assembly on a substrate
A method of component assembly on a substrate, and an assembly of a bound component on a substrate. The method comprises the steps of forming a free-standing component having an optical characteristic; providing a pattern of a first binding species on the substrate or the free standing component; and forming a bound component on the substrate through a binding interaction via the first binding species; wherein the bound component exhibits substantially the same optical characteristic compared to the free-standing component.
US08722436B2 Method and apparatus for accurate die-to-wafer bonding
A method of light-emitting diode (LED) packaging includes coupling a number of LED dies to corresponding bonding pads on a sub-mount. A mold apparatus having concave recesses housing LED dies is placed over the sub-mount. The sub-mount, the LED dies, and the mold apparatus are heated in a thermal reflow process to bond the LED dies to the bonding pads. Each recess substantially restricts shifting of the LED die with respect to the bonding pad during the heating.
US08722433B2 Method for fabricating light emitting diode (LED) dice with wavelength conversion layers
A method for fabricating light emitting diode (LED) dice includes the steps of mixing wavelength conversion particles in a base material to a first weight percentage, mixing reflective particles in the base material to a second weight percentage, curing the base material to form a wavelength conversion layer having a selected thickness, and attaching the wavelength conversion layer to a die.
US08722431B2 FinFET device fabrication using thermal implantation
A method of forming a FinFET device. The method may include providing a substrate having a single crystalline region, heating the substrate to a substrate temperature effective for dynamically removing implant damage during ion implantation, implanting ions into the substrate while the substrate is maintained at the substrate temperature, and patterning the single crystalline region so as to form a single crystalline fin.
US08722430B2 Production method for oxidized carbon thin film, and element having oxidized carbon thin film and production method therefor
The production method for the oxidized carbon thin film of the present disclosure includes: a first step of preparing a carbon thin film and iron oxide that is in contact with the carbon thin film and contains Fe2O3; and a second step of forming an oxidized carbon thin film having an oxidized portion composed of oxidized carbon by applying a voltage or current between the carbon thin film and the iron oxide with the carbon thin film side being positive and thereby oxidizing a contact portion of the carbon thin film with the iron oxide to change it into the oxidized portion. This production method allows a pattern of nanometer order to be formed on a carbon thin film represented by graphene. The method causes less damage to the formed pattern and has high affinity with a semiconductor process, thereby enabling a wide range of applications as a process technique for producing an electronic device.
US08722423B2 Assay method utilizing capillary transport on non-porous substrates
A device and method for the separation of a component in a liquid sample prior to the detection of an analyte in said sample, wherein a sample is added to a receiving zone on a substrate, said substrate further optionally comprising a reaction zone, a transport or incubation zone connecting the receiving and reaction zone, respectively, forming a flow path on a substrate, wherein said substrate is a non-porous substrate, and at least part of said flow path consists of areas of projections substantially vertical to said surface, and having a height (H), diameter (D) and reciprocal spacing (t1, t2) such, that lateral capillary flow of said liquid sample in said zone is achieved, and where means for separation are provided adjacent to the zone for receiving the sample. Said means for separation are chosen among filter means, optionally enhanced by affinity binding and/or aggregation; magnetic means, also optionally enhanced by affinity binding and/or aggregation; and acoustic means.
US08722419B2 Flow cytometry methods and immunodiagnostics with mass sensitive readout
Mass cytometry method. In one aspect, the method includes providing a sample having at least one cell type and mixing the sample with material such as nanoparticles functionalized with affinity molecules for the at least one cell type. The sample is transported through a suspended microchannel resonator to record a mass histogram and a cell count for the at least one cell type is determined from the histogram.
US08722418B1 Thermal indicating composition
A reversible, colored thermal indicating composition, whose chromaticity provides a measure of the elapsed time within specific elevated temperature bands—the composition containing one or more polydiacetylenes (PDAs) in combination with ZnO alloyed with a transition metal oxide, such as ZrO2 and/or TiO2.
US08722416B2 Integrated on-line two-dimensional method and device for synchroned analytical temperature rising elution fractionation and gel permeation chromatography
An analytical method comprising performing a first fractionation of a polymer sample based on differences in crystallizability to provide a first set of sample fractions, performing a first analysis on the first set of sample fractions, performing a second fractionation of the first set of sample fractions to produce a second set of sample fractions, performing a second analysis on the second set of sample fractions, and synchronizing the first fractionation and second fractionation to provide about concurrent analysis of the polymer sample.
US08722414B2 Device and method for the control of chemical processes
The present invention provides a method of controlling a chemical process, the method comprising the steps of: (i) providing a laminar flow of a first fluid, the first fluid providing a first reagent or one or more precursor thereof), a laminar flow of a second fluid, the second fluid providing a second reagent (or one or more precursor thereof) and a laminar flow of barrier fluid; and (ii) causing the first and barrier fluids to contact one another so that the barrier fluid forms a barrier between the first reagent (or one or more precursor thereof) and the second reagent (or one or more precursor thereof) wherein step (ii) comprises forming segments of first fluid encased or sandwiched by barrier fluid, the segments being surrounded by the second fluid, and the barrier fluid is permeable to one or both of the first and second reagents. Devices for performing the method of the present invention are also provided.
US08722413B1 Biodiesel automatic titration system
An automated system and process for the titration of either Waste vegetable oil (WVO) or virgin vegetable oil during its chemical conversion into Biodiesel. A system capable of automatically measuring and controlling the addition of a suitable amount of titration fluid is controlled in reaction to a pH level measurement tool, as determined by sensors and software. The process comprises forming a single phase solution of WVO and titrant in a ratio of between 10:1 to 50:1.
US08722411B2 Brucella phage polynucleotides and uses thereof
An isolated polynucleotide is disclosed which comprises a nucleic acid sequence of a Brucella phage, the nucleic acid sequence being specific to the Brucella phage and comprising a sequence selected from the group consisting of SEQ ID NOs: 387-393. An exemplary polynucleotide sequence is one which comprises at least 100 consecutive nucleotides of a nucleic acid sequence as set forth in SEQ ID NO: 396. Uses of such sequences are further disclosed.
US08722407B2 Method and apparatus for tissue transfer
A handheld tool is disclosed which may be used to transfer a plurality of plant tissue explants from a first container to a second container. The handheld tool may include a disposable tip member which couples the plurality of plant tissue explants through use of negative pressure. An automated system which transfers a plurality of plant tissue explants from a first container to a second container is also disclosed. The automated system may include a first presentment system which moves the first container to a region, a second presentment system which moves the second container to the region, and a robot system that transfers the plurality of plant tissue explants from the first container to the second container.
US08722405B2 Composition and method for enabling proliferation of pluripotent stem cells
The present disclosure is directed to the development of compositions, such as extracellular matrices, and processes for using the same, for culturing stem cells in vitro in an undifferentiated state. In this regard, it has been discovered that when pluripotent mouse and human embryonic stem cells are cultured on plates coated with recombinant laminin-10 (laminin-511) or laminin-5 (laminin-322), or their functional domains, the embryonic stem cells proliferated and maintained their pluripotency.
US08722397B2 Method for detecting and quantifying endogenous wheat DNA sequence
A circular DNA is provided comprising endogenous DNA common to both genetically modified wheat and non-genetically modified wheat along with one or more pieces of DNA each having a sequence present specifically in a strain of genetically modified wheat. Also provided is a method for determining a mix rate of genetically modified wheat in a test sample.
US08722393B2 Apparatus for facilitating evaluating migration of cells in vitro
Method and apparatus for processing a cell culture are provided. The method includes establishing a cell culture within a holding device having one or more wells, each well holding a cell culture, and including a well substrate with at least one electrode in contact with the cell culture; periodically applying at least one electrical pulse to the at least one electrode to prevent cells from attaching to and achieving confluence over the at least one electrode while allowing cells to attach to and achieve confluence over other portions of the well substrate; and discontinuing the periodically applying of the at least one electrical pulse to the at least one electrode after cells have achieved confluence over the other portions of the well substrate, and thereafter, monitoring the cell culture to monitor migration of cells over the electrode(s) from the other portions of the well substrate.
US08722387B2 Microorganisms for C4-dicarboxylic acid production
The present invention relates to isolated polypeptides having bicarbonate transporter activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, and methods of producing C4-dicarboxylic acids, such as malic acid.
US08722381B2 Variants of a Bacillus strearothermophilus alpha-amylase and uses thereof
Described are variants of alpha (α)-amylases having altered starch hydrolysis profiles. The variants have improved thermostability and increased specific activity, resulting in reduced peak viscosity and altered final viscosity during starch liquefaction. The amylase variants are useful, e.g., in liquefaction and other starch degradation processes.
US08722380B2 DNA polymerases with increased 3′-mismatch discrimination
Disclosed are mutant DNA polymerases having increased 3′-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
US08722379B2 DNA polymerases with increased 3′-mismatch discrimination
Disclosed are mutant DNA polymerases having increased 3′-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
US08722378B2 DNA polymerases with increased 3′-mismatch discrimination
Disclosed are mutant DNA polymerases having increased 3′-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
US08722376B2 Firefly luciferase
According to one embodiment, the present invention relates to luciferase derived from Malaysian Luciola firefly, the luciferase having a maximum luminescent wavelength of 580 nm at pH 8, or the luciferase indicating 23.3 times or more of luminescent intensity in comparison to that of Rhodamine 6G.
US08722373B2 Contaminant control in Zymomonas fermentation using virginiamycin
Contamination was controlled in fermentations using Zymomonas mobilis as the biocatalyst, without negative impact on fermentation production, by the addition of virginiamycin. The effective concentration of virginiamycin was found to be dependent upon the type of fermentation medium used.
US08722368B2 Method for preparing a counter-tagged population of nucleic acid molecules
Aspects of the present invention include methods and compositions for determining the number of individual polynucleotide molecules originating from the same genomic region of the same original sample that have been sequenced in a particular sequence analysis configuration or process. In these aspects of the invention, a degenerate base region (DBR) is attached to the starting polynucleotide molecules that are subsequently sequenced (e.g., after certain process steps are performed, e.g., amplification and/or enrichment). The number of different DBR sequences present in a sequencing run can be used to determine/estimate the number of different starting polynucleotides that have been sequenced. DBRs can be used to enhance numerous different nucleic acid sequence analysis applications, including allowing higher confidence allele call determinations in genotyping applications.
US08722365B2 Metabolically engineered Escherichia coli for enhanced production of sialic acid
A metabolically engineered E. coli strain which produces sialic acid and a method of making said strain. In the engineered E. coli cells, the nanT (sialic acid transporter) and nanA (sialic acid adolase) genes are inactivated, and the neuC and neuB genes of sialic acid biosynthesis in Neisseria meningitidis group B are introduced and overexpressed in the nanT− nanA− E. coli cell. In addition, the glucosamine synthase gene, glmS, of E. coli is co-overexpressed with neuB and neuC.
US08722364B2 Method for increasing microbial catalase production
Disclosed are methods for increasing microbial catalase production. 1-10 g/L sodium hexametaphosphate was added to the culture medium between 30-40 hours of fermentation to inhibit proteinase activity and increase the production of catalase. This simple modification of fermentation procedure can result in up to 45% increase of the production of catalase.
US08722358B2 Method for obtaining structural and functional information on proteins, based on polarization fluorescence microscopy
The invention pertains to a method of obtaining structural and functional information on proteins, based on polarization fluorescence microscopy, which comprises subjecting a protein tagged with a fluorophore to two- or multi-photon fluorescence microscopy, whereas the observed protein is irradiated with a laser beam with light of at least two different polarizations, which excites the fluorescence of the fluorophore, and wherein information on localization, intensities and polarizations of the fluorescence excited by the different polarizations of the excitation laser beam is used to identify, localize and quantify anisotropy of absorption and/or fluorescence, which information is then used to infer structural and functional properties of proteins. An example of a device for obtaining structural and functional information on proteins, based on polarization fluorescence microscopy, comprises a modulator (P) for rapid modulation of the excitation beam (1) for eliciting two- or multi-photon fluorescence, and a control unit (R), wherein the function of the modulator (P) and control unit (R) is synchronized with scanning of the microscope (M) such that information on fluorescence intensity acquired by the microscope (M) is attributable to a particular polarization state of the excitation beam (1) by virtue of knowing the temporal profile of the polarization modulation of the excitation beam (1) effected by the modulator (P). The method and device of the invention allow determining and monitoring structure and function of proteins, such as membrane proteins, and thereby observing physiological processes in living cells.
US08722348B2 Method and composition for a protein transduction technology and its applications
A protein transduction method for efficiently delivery of exogenous proteins into mammalian cells is invented, which has the capability of targeting different cellular compartments and protection from degradation of the delivered proteins from cellular proteases. A composition for treat proteins has cation reagents, lipids and enhancers in a carrier. The method can be used in a number of ways including: production of large quantities of properly folded, post-translationally modified proteins using mammalian cell machinery, a in-cell fluorescence spectroscopy and imaging using small molecule fluorophores and a in-cell NMR spectroscopy using living mammalian cells. The method permits cell biology at atomic resolution that is physiologically and pathological relevant and permits protein therapy to treat human diseases. The method can also be used to deliver exogenous protein inside mammalian cells, wherein the exogenous proteins follow a similar secretion pathway as that of the endogenous protein.
US08722346B2 Chemiluminescence compact imaging scanner
Systems, devices, and methods for accurately imaging chemiluminescence and other luminescence are disclosed. A compact, flat-bed scanner having a light-tight enclosure, one or more detector bars of linear charge-coupled device (CCD) or complementary metal oxide semiconductor (CMOS) imaging chips, and high working numerical aperture (NA) optics scans closely over a sample in one direction and then the opposite direction. Averages or other combinations of intensity readings for each pixel location (x, y) between the two or more passes are averaged together in order to compensate for luminescence that varies over time. On-chip pixel binning and multiple clock frequencies can be used to maximize the signal to noise ratio in a CCD-based scanner.
US08722343B2 Methods and compositions for the diagnosis and treatment of diabetes
Methods, assays and compositions for the diagnosis and treatment of diabetes, in which the glutamate transporters and/or receptors expressed in pancreatic islet cells are used as therapeutic targets or tools for the identification or treatment of individuals suffering from or susceptible to diabetes.
US08722342B2 Method for enhancing sensitivity or method for avoiding influence of hemoglobin in immunological measurement
A method for enhancing measurement sensitivity or avoiding hemoglobin influence in a latex agglutination or metal agglutination immunoassay method of a target antigen in a biological sample that uses calixarene in the immunoassay.
US08722339B2 Immunoassay methods
The invention relates to a method of detecting a disease state or disease susceptibility in a mammalian subject which comprises detecting an antibody in a test sample comprising a bodily fluid from said mammalian subject wherein said antibody is a biological marker of a disease state or disease susceptibility, the method comprising: (a) contacting said test sample with a plurality of different amounts of an antigen specific for said antibody, (b) detecting the amount of specific binding between said antibody and said antigen, (c) plotting or calculating a curve of the amount of said specific binding versus the amount of antigen for each amount of antigen used in step (a) and (d) determining the presence or absence of said disease state or disease susceptibility based upon the amount of specific binding between said antibody and said antigen at each different antigen concentration used.
US08722338B2 Modulation of ABCG2-mediated urate transport to treat hyperuricemia and gout
Genome-wide association studies (GWAS) was recently used to identify SNPs in a genomic region on chromosome 4 that associate with serum urate levels and gout. The present disclosure shows that human ATP-binding cassette, subfamily G, 2 (ABCG2), encoded by the ABCG2 gene contained in this region, is a hitherto unknown urate efflux transporter. The present disclosure further shows that native ABCG2 is located in the brush border membrane of kidney proximal tubule cells, where it mediates renal urate secretion. Introduction of the mutation Q141K encoded by the common SNP rs2231142 by site-directed mutagenesis resulted in reduced urate transport rates compared to wild-type ABCG2. Data from a population-based study of 14,783 individuals support rs2231142 as the causal variant in the region and show highly significant associations with urate levels and gout.
US08722336B2 Restriction endonuclease enhanced polymorphic sequence detection
Provided in part herein is an improved method for the detection of specific polymorphic alleles in a mixed DNA population. The method comprises enriching the relative percentage of a given polymorphic allele that is exponentially amplifiable by PCR. Provided also are methods for selectively enriching target nucleic acid, for example, fetal nucleic acid in a maternal sample. In the case of detecting fetal nucleic acid in a maternal sample, a restriction enzyme is introduced that can discriminate between the alleles of a polymorphic site. In some embodiments, the maternal allele is digested and nucleic acid comprising the paternal allele is relatively enriched.
US08722335B2 Methods and kits used in the detection of fungus
The invention encompasses methods of using quantitative PCR to detect fungal organisms in clinical and environmental samples and to generate standards that allow the quantification of fungal organisms in the samples.
US08722331B2 Method for selecting a treatment for non-small cell lung cancer using gene expression profiles
The present invention identifies and quantifies changes in gene expression associated with non-small cell lung cancer NSCLC by examining gene expression in tissue from normal lung and diseased lung. The present invention also identifies and quantifies expression profiles which serve as useful diagnostic markers as well as markers that are useful to monitor disease states, disease progression, drug toxicity, drug efficacy and drug metabolism.
US08722329B2 Microfluidic device-based nucleic acid purification method
A method is provided for purifying nucleic acid from a sample in a microfluidic device. The method can be used to purify nucleic acids from any source known in the art that comprises nucleic acids, such as prokaryotic or eukaryotic organisms, viruses, cell, tissues, organs, etc. In a specific example, the tissue is whole blood. The method for purifying nucleic acid may run fully automated in the microfluidic device.
US08722328B2 Methods, compositions, and kits for recovery of nucleic acids or proteins from fixed tissue samples
Methods and materials for improving nucleic acid or protein recovery from samples preserved in liquid cytological preservative solutions by utilizing scavenging agents, such as hydrazine- and hydrazide-containing compounds, are provided. Lysis solutions comprising hydrazine- and hydrazide-containing compounds and kits comprising the same are also provided.
US08722327B2 Methods of macromolecular analysis using nanochannel arrays
Methods of analyzing features such as the physical size of macromolecules or biomarkers along large genomic DNA molecules were disclosed as well as the devices for carrying out such high throughput analysis in a massively parallel fashion. Methods of fabricating such devices are also disclosed.
US08722322B2 Photonic heating of silver grids
A method of improving conductivity of a metal pattern (18) includes providing a developed silver pattern (14) formed from a photographic silver salt provided in a binder coated on a substrate (12); and selectively heating the silver pattern with electromagnetic radiation.
US08722320B2 Lithography method and device
Lithography methods and devices are shown that include a semiconductor structure such as a mask. Methods and devices are shown that include a pattern of mask features and a composite feature. Selected mask features include doubled mask features. Methods and devices shown may provide varied feature sizes (including sub-resolution) with a small number of processing steps.
US08722319B2 Pattern forming method, chemical amplification resist composition and resist film
A pattern forming method includes: (i) forming a film from a chemical amplification resist composition that contains (A) a resin, (B) a compound capable of generating an acid upon irradiation with an actinic ray or radiation and (C) a tertiary alcohol; (ii) exposing the film; and (iii) performing development by using a developer containing an organic solvent.
US08722318B2 Methods of photochemical hydrolysis-polycondensation of cross-linkable chromophores with steric hindrance, catalysed by a photogenerated acid, and the applications thereof
The invention relates to a process for the hydrolysis-polycondensation of a sterically hindered crosslinkable chromophore, characterized in that the hydrolysis-polycondensation is catalyzed with an acid released by a photoacid generator (PAG).
US08722316B2 Process for realization of polymeric materials with second order nonlinear electro-optical properties and electro-optical devices made with said material
The present invention concerns a process for realization of polymeric materials with second order nonlinear electro-optical properties comprising the following steps: mixing of a chromophore with nonlinear optical properties with two or three hydroxy groups; isolation of said pure bi- or tri-isocyanate NLO chromophores obtained according to the above step; dissolution of said bi- or tri-isocyanate NLO chromophores obtained according to the above step in one or more isocyanate group not reactive solvents containing reactive substances; coating of a thin layer of said prepolymer mixture on a substrate and evaporation of said not reactive solvents; cross-linking and poling of said thin layer on substrate, by means of heating and application of an electric field; cooling of said thin cross-linked and poled layer at ambient temperature maintaining the applied poling electric field; switching off the poling electric field.
US08722314B2 Method for producing conductive sheet and method for producing touch panel
A first exposure treatment for irradiating a first photosensitive layer formed on one main surface of a transparent support with a first light thereby to expose the first photosensitive layer and a second exposure treatment for irradiating a second photosensitive layer formed on the other main surface of the transparent support with a second light to expose the second photosensitive layer are performed such that the first light incident on the first photosensitive layer does not substantially reach the second photosensitive layer and the second light incident on the second photosensitive layer does not substantially reach the first photosensitive layer.
US08722313B2 Touch screen panel and method of manufacturing the same
A method of manufacturing a touch screen panel includes a first process, a second process, and a third process. Each of a plurality of first electrode serials includes a plurality of first electrode patterns which are separated from each other, neighboring first electrode patterns are electrically connected to each other via a first connection pattern, and a first insulation pattern electrically insulates the first electrode serial from the second electrode serial at an intersection of the first electrode serial and the second electrode serial.
US08722299B2 Curable toner compositions and processes
Processes for producing emulsion aggregation toners are provided. In embodiments, methods of the present disclosure may be utilized to produce toners suitable for low melt applications, including use in flexible packaging applications, where low pile height is desired for low cost and flexibility. In embodiments, the EA toners may include small particles having a shell with a high amount of resin, which optimizes the charging characteristics of the toner.
US08722294B2 Baroplastic, resin composition, electrostatic-image-developing toner, electrostatic image developer, toner cartridge, process cartridge, image forming apparatus and image forming method
A baroplastic includes a first resin with a first Tg; and a second resin with a second Tg that is lower than the first Tg by 20° C. or more, and has a photoreactive group.
US08722292B2 Electrostatic image developing toner, invisible information toner, electrostatic image developer, process cartridge and image formation apparatus
The invention relates to an electrostatic image developing toner comprising at least one of a phthalocyanine type compound and a naphthalocyanine type compound and at least one compound represented by the following structural formulae (1) to (10): wherein R1 to R57 respectively represent a hydrogen atom, an alkyl group, an aryl group, an arylalkyl group, an amino group, a halogen group, an alkoxy group, an alkylthio group, a nitro group, a hydroxy group, a thiol group, an alkylcarbonyl group, an alkoxycarbonyl group, an alkylcarbonylamino group, an alkoxycarbonylamino group, a carboxyamide group or a nitroimino group, wherein among R1 to R57, any two adjacent Rs may form a carbon ring and any two Rs connected to the same carbon atom may form an oxo group, an imino group or a thioxo group.
US08722291B2 Electrostatic charge image developer, process cartridge, image forming apparatus, and image forming method
Provided is an electrostatic charge image developer including a first toner that contains a binder resin and a brilliant pigment, a second toner that contains a binder resin without a brilliant pigment, and a carrier, wherein the developer satisfies the following formulae, 5 μm≦A≦30 μm  (1): 1 μm≦B≦15 μm  (2): 3.0≦C/A≦5.0  (3): 5.0≦C/B≦20.0  (4): wherein A represents a volume average particle size of the first toner, B represents a volume average particle size of the second toner, and C represents a volume average particle size of the carrier.
US08722290B2 Toner, developer, toner cartridge, and image forming apparatus
Provided is a toner wherein when a solid image formed by the toner is irradiated with incident light at an incident angle of −45° using a goniophotometer, a ratio (A/B) of a reflectance A at a light-receiving angle of +30° to a reflectance B at a light-receiving angle of −30° is about 2 or more and about 100 or less.
US08722288B2 Diphenylnaphthylamine derivatives
[Problems] To provide a novel compound which has a high carrier mobility and is useful as a charge-transporting agent that is not only capable of stably forming a photosensitive layer without precipitating crystals or forming pinholes at the time of forming the photosensitive layer but is also capable of forming an organic photosensitive material for electrophotography that has a high sensitivity and a low residual potential.[Means for Solution] A diphenylnaphthylamine derivative represented by the following general formula (1), wherein R1 to R3 are alkyl groups, k is an integer of 0 to 3, j is an integer of 0 to 4, l is an integer of 0 to 6, and X1 and X2 are hydrocarbon groups having at least one ethylenically unsaturated bond.
US08722286B2 Devices and methods for improved reflective electron beam lithography
A device for reflective electron-beam lithography and methods of producing the same are described. The device includes a substrate, a plurality of conductive layers formed on the substrate, which are parallel to each other and separated by insulating pillar structures, and a plurality of apertures in each conductive layer. Apertures in each conductive layer are vertically aligned with the apertures in other conductive layers and a periphery of each aperture includes conductive layers that are suspended.
US08722283B2 Fuel cell
A fuel cell includes a stack of electrolyte electrode assemblies and metal separators. Each of the electrolyte electrode assemblies includes an electrolyte and a pair of electrodes sandwiching the electrolyte between the pair of electrodes. The fuel cell includes a coolant channel. The coolant channel is formed between the metal separators that are adjacent to each other to allow a coolant to flow through the coolant channel, and has grooves. The coolant channel includes an inclined coolant channel group in which overlapping portions of the grooves facing each other are connected along flow of the coolant that is oriented diagonally inward with respect to a longitudinal direction. The inclined coolant channel group includes inclined coolant channels whose downstream ends are connected to a downstream center of the coolant channel and whose upstream ends are connected to coolant inlet manifolds.
US08722282B2 Power unit and cartridge, and fuel cell system comprising power unit and cartridge
A power unit, a fuel cartridge, and a fuel cell system having the power unit and the fuel cartridge. The power unit includes a coupling unit to couple with the fuel cartridge. The coupling unit includes a nozzle that receives fuel supplied from the fuel cartridge, a selection key to selectively mate with the fuel cartridge, and an outer unit surrounding the nozzle. An end of the nozzle is located between the selection key and an end of the outer unit.
US08722274B2 Datum insert for shorting protection on a fuel cell plate
A subassembly for a fuel cell stack includes a fuel cell plate and a datum hole formed in the fuel cell plate for alignment of the fuel cell plate during assembly of the fuel cell stack. The subassembly also includes a datum insert disposed adjacent the datum hole of the fuel cell plate. The datum insert is configured to militate against a bending of the fuel cell plate at the datum hole during the assembly of the fuel cell stack.
US08722269B2 Fuel cell system and scavenging method therefor
A fuel cell system includes a scavenging gas supply device for supplying a scavenging gas to a fuel cell stack; a scavenging switching valve for performing switching between first scavenging for performing scavenging by supplying the scavenging gas to one of a cathode gas passage and an anode gas passage, and second scavenging for performing scavenging by supplying the scavenging gas to the other gas passage; a pressure control device for controlling the pressure of the scavenging gas; and a control part for controlling operations of the scavenging gas supply device, the scavenging switching valve, and the pressure control device. When the scavenging is switched from the first scavenging to the second scavenging via the scavenging switching valve, the pressure of the scavenging gas at the upstream side with respect to the scavenging switching valve becomes lower than the pressure of the scavenging gas during the first scavenging.
US08722264B2 Algorithm for stack current controller based on polarization curve estimation of a fuel cell stack
A method for providing a current density set-point for a fuel cell stack in response to a power request from the stack where the set-point is determined based on system parameters that identify the life and degradation of the stack. The method includes dividing a current density range of the fuel cell stack into a predetermined number of sample regions, and selecting the sample regions in order from low to high during the current set-point analysis. The method calculates an average cell voltage for the current density of the selected sample region, and stack power from the average cell voltage. The method then determines whether a power request signal is less than the stack power for the selected sample region and greater than the calculated power for the previous sample region, and if so, calculates the current density set-point at the requested power based on these values.
US08722257B2 Pressing-type cylindrical metal air battery
The present invention provides a pressing-type cylindrical metal air battery which comprises: an external case which is formed in a cylindrical shape, and has a cathode terminal on one side and an anode terminal hole on the other side; an internal case which is formed in a cylindrical shape and coaxially inserted into the inside of the external case, has an anode terminal that is inserted into or extracted from the inside or the outside of the anode terminal hole on one side, and has an air inflow hole on the surface of a wall so that air can flow into the air inflow hole; and an elastic sealing means which is formed on the one side of the internal case, enables the air to flow into the anode terminal hole by elastically pressurizing the anode terminal when a battery is inserted into a battery compartment, and seals the anode terminal hole by elastically restoring the anode terminal again if the battery is separated from the battery compartment.
US08722254B2 Flexible solid state conductors including polymer mixed with protein
Various embodiments of solid-state conductors containing solid polymer electrolytes, electronic devices incorporating the solid-sate conductors, and associated methods of manufacturing are described herein. In one embodiment, a solid-state conductor includes poly(ethylene oxide) having molecules with a molecular weight of about 200 to about 8×106 gram/mol, and a soy protein product mixed with the poly oxide), the soy protein product containing glycinin and β-conglycinin and having a fine-stranded network structure. Individual molecules of the poly(ethylene oxide) are entangled in the fine-stranded network structure of die soy protein product, and the poly(ethylene oxide) is at least 50% amorphous.
US08722252B2 Current carrying block for resistance welding, and method for manufacturing sealed battery and sealed battery each using the current carrying block
In a sealed battery, a metal current carrying block 24A having a protrusion 24b on each of the two opposing faces is placed between positive or negative electrode substrate exposed portions that are divided into two so as to bring the protrusion 24b on each of the two opposing faces into contact with the positive or negative electrode substrate exposed portions that are stacked, a pair of electrodes 31 and 32 for resistance welding are brought into contact with positive electrode collector members 16 or negative electrode collector members that are each placed on the outermost surfaces of the positive electrode substrate exposed portions 14 or negative electrode substrate exposed portions, and resistance welding is performed with pressure applied between the pair of electrodes 31 and 32 for resistance welding.
US08722251B2 Active material, nonaqueous electrolyte battery and battery pack
According to one embodiment, an active material includes a monoclinic system β-type titanium composite oxide. The monoclinic system β-type titanium composite oxide includes a first element including at least one of Mo and W and satisfies the following formula (1): B>A  (1) In the formula, A is an intensity of a peak which is derived from (110) plane of the monoclinic system β-type titanium composite oxide in a wide-angle X-ray diffraction pattern. B is an intensity of a peak which is derived from (002) plane of the monoclinic system β-type titanium composite oxide in the wide-angle X-ray diffraction pattern.
US08722236B2 Battery
In one embodiment, a battery includes an exterior can, an electrode group, a lid attached to an opening of the exterior can, and anode and cathode terminal portions arranged in the lid. At least one of the terminal portions includes an insulating gasket having a cylindrical portion, an external insulator having a pedestal portion, an external terminal including a head portion and the axial portion extended from the head portion, an electrode lead located in the exterior can and connected to the external terminal, and an internal insulator to isolate the lid and the electrode lead. The cylindrical portion of the external terminal is fixed to a through hole of the lid and an attachment hole of the electrode lead by a caulking. The insulating gasket is formed of a resin in which the melting point is higher than those of the internal insulator and the external insulator.
US08722232B2 Electrochemical device
An electrochemical device includes a container, a storage element, and a structure. The container includes a container main body including a first inner surface, and a lid including a second inner surface that is opposed to the first inner surface, the lid being joined to the container main body. The storage element includes a first electrode layer that is bonded to the first inner surface, a second electrode layer that is bonded to the second inner surface, and a separator that is provided between the first electrode layer and the second electrode layer, the storage element being sandwiched between the first inner surface and the second inner surface. The structure is provided to at least one of the first inner surface and the second inner surface, at least partially embedded in an inside of at least one of the first electrode layer and the second electrode layer, and made of a cured conductive adhesive.
US08722228B2 Moisture activated battery
A battery includes a first battery. The first battery includes a first anode, a first cathode, and a dry electrolyte. The dry electrolyte is configured to be activated by a first biological fluid to electrically connect the first anode and the first cathode to generate an electrical current.
US08722225B2 Battery module including improved base plate
A battery module includes a base plate, a plurality of batteries on the base plate, and a reinforcing portion on the base plate for reinforcing the base plate. Therefore, deformation of the base plate is prevented.
US08722224B2 Middle or large-sized battery pack of improved cooling efficiency
Disclosed is a battery pack configured to have a structure in which two or more battery modules, each including a plurality of battery cells or unit modules (unit cells) which can be charged and discharged, are mounted in a space defined between a pack case and a base plate, wherein cooling members, each including a heat dissipation fin disposed in contact with outsides of corresponding ones of the unit cells and a coolant conduit connected to a lower end of the heat dissipation fin to allow a coolant to flow therealong, are mounted at interfaces between the unit cells, the base plate, located below the battery modules, is configured to form a coolant flow channel having a coolant flow direction corresponding to the coolant flow direction in the coolant conduit, the pack case is coupled to the base plate in a state in which the battery modules are mounted on the base plate.
US08722223B2 Battery pack
A battery pack includes a plurality of battery modules including at least a first group of the battery modules and a second group of the battery modules, a first coolant flow pathway through the battery modules of the first group and the second group, a second coolant flow pathway along an exterior of the battery modules of the first group, and a converging coolant flow pathway connected with the first coolant flow pathway, the converging coolant flow pathway being disposed downstream of the first group of the battery modules, the converging coolant flow pathway joining the second coolant flow pathway with the first coolant flow pathway.
US08722216B2 Cathode design
A cathode for a fuel cell comprising a catalyst layer; a backing layer mounted to an aperture in a fuel chamber of said fuel cell; 1) wherein said catalyst layer is mounted to the backing layer on a face opposed to the aperture, so as to be in fluid communication with atmospheric oxygen in the case of microbial fuel cell; and 2) wherein said catalyst layer is mounted to the backing layer on a face opposed to the aperture, so as to be in fluid communication with water in the case of microbial electrolysis cell.
US08722215B2 Glass substrate for information recording medium and information recording medium
A glass substrate for information recording medium, said glass substrate being composed of an alminosilicate glass containing 60-75% by mass of SiO2, 5-18% by mass of Al2O3, 3-10% by mass of Li2O, 3-15% by mass of Na2O and 0.5-8% by mass of ZrO2 relative to the entire glass components. The glass substrate for information recording medium contains neither As (arsenic) nor Sb (antimony), while containing at least one polyvalent element selected from the group consisting of V (vanadium), Mn (manganese), Ni (nickel), Nb (niobium), Mo (molybdenum), Sn (tin), Ce (cerium), Ta (tantalum) and Bi (bismuth). The molar ratio of the total amount of the polyvalent elements to the amount of ZrO2 is within the range of 0.05-0.50.
US08722214B2 Hybrid grain boundary additives in granular media
Magnetic layers are described that include the use of magnetic grains and non-magnetic grain boundaries with hybrid additives. Hybrid additives include the use of at least two different additives in the composition of the grain boundaries of a magnetic layer in magnetic recording media. The use of hybrid additives in the grain boundaries results in improved recording media. Methods for forming magnetic layers and magnetic recording media with the hybrid additive grain boundaries are also described.
US08722210B2 Low emissivity glass and method for manufacturing the same
The present invention relates to low emissivity glass and to a method for manufacturing the same. The low emissivity glass comprises: a low emissivity layer; and a dielectric layer formed on the low emissivity layer, wherein the glass has an emissivity of 0.01 to 0.3 and a visible transmittance of 70% or more. According to the present invention, low emissivity glass having good emissive performance while also exhibiting high visible transmittance can be provided. Further, according to the present invention, the manufacturing process for the above-described low emissivity glass can be simplified, and initial investment amount can be reduced.
US08722205B2 Heteroleptic iridium complex
Novel compounds comprising heteroleptic iridium complexes are provided. The compounds have a particular combination of ligands which includes a single pyridyl dibenzo-substituted ligand as exemplified by Formula I, where X is NR, O, S, BR, or Se. The compounds may be used in organic light emitting devices, particularly as emitting dopants, to provide devices having improved efficiency, lifetime, and manufacturing.
US08722203B2 Steel, for hot forming or quenching in a tool, having improved ductility
The invention relates to a steel part, the composition of the steel of which comprises, the contents being expressed by weight: 0.040%≦C≦0.100%; 0.80%≦Mn≦2.00%; Si≦0.30%; S≦0.005%; P≦0.030%; 0.010% S≦Al≦0.070%; 0.015%≦Nb≦0.100%; 0.030% Ti≦0.080%; N≦0.009%; Cu≦0.100%; Ni≦0.100%; Cr≦0.100%; Mo≦0.100%; and Ca≦0.006%, the balance of the composition consisting of iron and inevitable impurities resulting from the smelting, the microstructure of the steel consisting of at least 75% equiaxed ferrite, martensite in an amount not less than 5% but not exceeding 20%, and bainite in an amount not exceeding 10%.
US08722202B2 Method and system for enhancing heat transfer of turbine engine components
A method and system for enhancing the heat transfer of turbine engine components is disclosed that includes applying a metallic coating having a high thermal conductivity to the cold side of a turbine component to enhance heat transfer away from the component. The metallic coating may be roughened to improve heat transfer. The metal coating may be a Ni—Al bond coating having an aluminum content greater than about 50 weight percent.
US08722196B2 Composite material, method of producing the same, and apparatus for producing the same
Proposed are a composite material having a high adhesiveness, wherein non-penetrating pores that are formed in a silicone surface layer are filled up with a metal or the like without leaving any voids by using the plating technique and the silicone surface layer is coated with the metal or the like, and a method of producing the composite material. A composite material, which has a high adhesiveness between a second metal or an alloy of the second metal (106a, 106b) and a silicone surface, can be obtained by filling up non-penetrating pores that are formed in the surface of a silicone substrate (100) substantially with a second metal or an alloy of the second metal (106a) with the use of the autocatalytic electroless plating technique wherein a first metal located at the bottom of the non-penetrating pores as described above serves as the starting point, and coating the surface of the silicone substrate (100) with the second metal (106b).
US08722191B2 Intermediate layer material and composite laminate
There is provided an intermediate layer material including a curing type resin composition and a fiber base material, to be used to form an intermediate layer of a composite laminate, wherein a cured material obtained by curing the intermediate layer material at a temperature of 180° C. has such properties as (i) a planar linear expansion coefficient (α1) equal to or lower than 20 ppm/° C., in a range equal to or higher than 25° C. and equal to or lower than a glass transition temperature (Tg); and (ii) a Barcol hardness equal to or more than 40 and equal to or less than 65, at 25° C.
US08722189B2 Cover glass for mobile terminals, manufacturing method of the same and mobile terminal device
To provide cover glass for mobile terminals exhibiting high strength in a thin plate thickness state to enable reductions in thickness of apparatuses when inserted in the apparatuses, cover glass (1) for a mobile terminal of the invention is cover glass (1) that is obtained by forming a resist pattern on main surfaces of a plate-shaped glass substrate, then etching the glass substrate with an etchant using the resist pattern as a mask, and thereby cutting the glass substrate into a desired shape and that protects a display screen of the mobile terminal, where an edge face of the cover glass (1) is formed of a molten glass surface, and as surface roughness of the edge face, arithmetic mean roughness Ra is 10 nm or less.
US08722188B2 Ceramic particle comprising an alumina crystalline phase
Disclosed is a process for producing ceramic particles, such as proppants, that have at least 10 percent total porosity. The process includes forming a particle precursor that includes 5 percent to 30 percent of a first ceramic material and at least 40 percent of a second ceramic material. The sintering temperature of the first ceramic material may be lower than the sintering temperature of a second ceramic material. Heating the precursor to a maximum temperature above the sintering temperature of the first material and below the sintering temperature of the second material. Also disclosed is a ceramic article that has a particular combination of chemistry and alumina crystalline phase.
US08722185B2 Pressure-sensitive adhesive sheet for glass plates
The present invention provides a pressure-sensitive adhesive sheet large in adhesive force when used for a surface of a glass member and capable of reducing the adhesive force to a degree allowing the occurrence of the cracking or breakage of the glass member to be suppressed when the sheet is peeled from the surface of the glass member. The pressure-sensitive adhesive sheet for glass plates of the present invention includes a pressure-sensitive adhesive layer including an acrylic polymer, wherein the content of the acrylic polymer in the pressure-sensitive adhesive layer is 30% by weight or more in relation to the total amount (100% by weight) of the pressure-sensitive adhesive layer; the acrylic polymer substantially includes no acidic functional group; the solvent-insoluble fraction of the pressure-sensitive adhesive layer is 50% or more; and the adhesive force to glass as determined by a specific method is 12.0 N or less.
US08722183B2 Coated article and method for making same
A coated article includes a substrate, an anti-corrosion layer formed on the substrate, and a decorative layer formed on the anti-corrosion layer. The substrate is made of magnesium or magnesium alloy. The anti-corrosion layer is a magnesium layer. The coated article has improved corrosion resistance.
US08722178B2 Syringe stopper
A syringe stopper that is suitable for use in syringes without silicone oil or other liquid lubricants. The invention provides a low friction barrier between an elastomeric stopper material and a therapeutic in the syringe. The barrier may inhibit materials from leaching from the elastomer material or from extraction of compounds from medicants by the elastomer. A process is also described that allows for molding thin barrier layers while allowing adequate bonding with the elastomer.
US08722177B2 Transfer mold body
In a transfer mold body, a display portion is formed from a crystalline resin and a main body portion is formed from an amorphous resin. Accordingly, a transfer layer is only transferred to the amorphous resin formed main body portion that has good transfer properties for the transfer layer, and the transfer layer is not transferred to the crystalline resin formed display portion that has poor transfer properties for the transfer layer. Accordingly, only the main body portion is decorated by the transfer layer, with the display portion to which the transfer layer is not transferred visibly displayed as the letter. Accordingly, since printing process is not necessary, suppressing an increase in cost of the transfer mold body. Moreover, the position of the letter is determined by two-color molding of the main body portion and the display portion, enabling positional displacement of the letter to be suppressed.
US08722175B2 Liquid composition, recording method, and recorded matter
A liquid composition, which contains: a water-soluble organic acid represented by the following general formula (1); a water-soluble amine represented by the following general formula (2); a water-soluble organic solvent; and water, wherein an amount of the water-soluble amine contained in the liquid composition is 0.9 or larger molar equivalent relative to acid groups contained in the water-soluble organic acid, where R1 is a hydroxyl group, a methyl group, or a hydrogen atom; and R2 is a hydroxyl group, or a methyl group, where R3 is a hydroxymethyl group; R4 is a methyl group, an ethyl group, or a hydroxymethyl group; and R5 is a hydrogen atom, a C1-4 alkyl group, or a hydroxymethyl group. The water-soluble organic acid and the water-soluble amine form a salt in the composition.
US08722174B2 Method of forming self-assembled patterns using block copolymers, and articles thereof
A method of forming a block copolymer pattern comprises providing a substrate comprising a topographic pre-pattern comprising a ridge surface separated by a height, h, greater than 0 nanometers from a trench surface; disposing a block copolymer comprising two or more block components on the topographic pre-pattern to form a layer having a thickness of more than 0 nanometers over the ridge surface and the trench surface; and annealing the layer to form a block copolymer pattern having a periodicity of the topographic pre-pattern, the block copolymer pattern comprising microdomains of self-assembled block copolymer disposed on the ridge surface and the trench surface, wherein the microdomains disposed on the ridge surface have a different orientation compared to the microdomains disposed on the trench surface. Also disclosed are semiconductor devices.
US08722170B1 Vehicular floor mat
A floor mat for a vehicle includes an adapter plate for engaging the vehicle's mat retaining system, a mat portion, and a fastener for securing the mat portion to the adapter plate. The configuration of the adapter plat allows the mat portion to be transversely, longitudinally, and rotationally aligned and secured to the vehicle's floor despite variations in the arrangements of different vehicles' mat retaining systems.
US08722165B2 Polyethylene additive compositions and articles made from same
A method comprising forming a polymeric composition by adding zinc oxide to a polymer wherein a pipe formed from the polymeric composition displays a time to failure as determined in accordance with ASTM F2263-07(E1) that is increased by greater than about 25% when compared to an otherwise similar pipe formed from a polymeric composition lacking zinc oxide. A pipe comprising polyethylene and greater than about 0.5 wt. % zinc oxide having a time to failure as determined in accordance with ASTM F2263-07(E1) that is at least about 25% greater than an otherwise similar pipe prepared in the absence of zinc oxide. A method comprising forming a composition comprising a polymer and zinc oxide into an article, and testing the structural integrity of the article when exposed to chlorinated water wherein the zinc oxide is present in an amount of from about 500 ppm to about 10000 ppm.
US08722162B2 Printable film
The invention relates to printable films comprising a substrate and at least a surface layer, said layer covering at least one face of said substrate and comprising a water-dispersible polymer and an ethylenically unsaturated compound; to a process for the manufacture of such films; to printed films and especially to printed labels obtained from such printable films.
US08722161B2 Heat shrinkable polyester film, method for producing same, and packaged body
Disclosed is a heat shrinkable polyester film formed from a polyester resin that is mainly composed of ethylene terephthalate and contains 3-12% by mole (inclusive) of one or more monomer components, which can be amorphous components, relative to all the polyester resin components, in which the heat shrinkable polyester film has a main shrinkage direction which is the width direction. The heat shrinkable polyester film is characterized in that the shrinkage in 80° C. glycerin, the shrinkage in 130° C. glycerin and the tensile breaking strength in the longitudinal direction are controlled within specific ranges.
US08722158B2 Liquid crystal photo-alignment agent and liquid crystal photo-alignment film manufactured using the same
Disclosed is a liquid crystal photo-alignment agent and a liquid crystal photo-alignment film manufactured using the same. The liquid crystal photo-alignment agent includes an epoxy compound represented by Chemical Formula 1, and a polymer including a polyamic acid, a polyimide, or a mixture thereof.
US08722157B2 Norbornene monomer, polynorbornene derivative, liquid crystal photoalignment film containing the same and liquid crystal display containing the same
The present invention relates to a norbornene monomer, a polynorbornene derivative, a liquid crystal alignment film including the same, and a liquid crystal display device including the same. More particularly, the present invention relates to a norbornene monomer, a polynorbornene derivative, a liquid crystal alignment film including the same, and a liquid crystal display device including the same, which have an alignment property by photoreaction, excellent thermal stability and photoreactivity, the increased photo-reaction rate and reliability of the alignment film, thereby showing high manufacturing process efficiency.
US08722156B2 Liquid crystal compound and liquid crystal display
An embodiment of the disclosure provides a liquid crystal compound having the following formula: wherein A1, A2, and A3 are independently hydrogen, halogen, cyano, thiocyanato, or —OCF3; R1 is hydrogen, halogen, C1-C12 alkyl, C1-C12 alkoxy, C1-C12 haloalkly, C2-C12 alkenyl, or C2-C12 alkynyl; R2 and R3 are independently hydrogen, halogen, C1-C6 alkyl, C1-C6 haloalkly, cyano, thiocyanato, or —OCF3; and Z is a single bond, —O—, —CH2O—, —C(O)O—, —OCO—, —C(O)NH—, or —CH═CH—. In another embodiment, a liquid crystal display including the liquid crystal compound is also provided.
US08722148B2 Coating compositions with alkoxy-containing aminofunctional silicone resins
This invention relates to a coating composition comprising (A) 100 weight parts of at least one epoxy resin; (B) 40 to 900 weight parts of at least one alkoxy-containing aminofunctional silicone resin; (C) up to 50 weight parts of at least one organic hardener; (D) up to 100 weight parts of at least one epoxyfunctional silicone resin; and (E) up to 10 weight parts of at least one cure accelerator, provided the alkoxy-containing aminofunctional silicone resin (B) has a total alkoxy content ranging from 26 to 80 mol percent per mole of silicon (Si) in the alkoxy-containing aminofunctional silicone resin. Methods for preparing the above-described composition and for treating substrates are also disclosed.
US08722145B2 Thermally protective materials
A mixture comprising an expandable graphite and a polymer resin is described wherein the polymer resin-expandable graphite mixture has a volume increase and structural integrity after exposure to heat. Methods are described for increasing the thermal protective performance (TPP) of textiles and laminates while optionally maintaining comfort, flexibility, and liquid protective properties.
US08722144B2 Thermal barrier coating method, masking pin and combustor transition piece
A thermal barrier coating method forms a thermal barrier coating by spray coating over the surface of a component where cooling holes are made. The thermal barrier coating is formed by spray coating after masking pins, which do not protrude above the surface of the component, are inserted into the cooling holes or masking pins protruding above the surface of the component are inserted and get shrunk due to heat while spray coating, obtaining the protruding amount equal to or less than the thickness of the thermal barrier coating after shrinkage, which characterizes the method. By way of this method, a thermal barrier coating can be formed all over the surface without clogging the cooling holes.
US08722143B2 Method to prepare superhydrophobic surfaces on solid bodies by rapid expansion solutions
The present invention refers to a method for preparing a superhydrophobic surface on a solid substrate comprising the steps of (a) providing a solvent in the form of a pressurized fluid in a vessel, wherein the fluid exhibits a decrease in solvency power with decreasing pressure; (b) adding a hydrophobic substance to the solvent as a solute, which substance is soluble with the pressurized fluid and has the ability to crystallize/precipitate after expansion of the fluid, thereby obtaining a solution of the solvent and the solute in the vessel; (c) having at least one orifice opened on the vessel, thereby causing the pressurized solution to flow out of the vessel and depressurize in ambient air or in an expansion chamber having a lower pressure than within the vessel, the solute thereby forming particles; and (d) depositing the particles on the substrate in order to obtain a superhydrophobic surface. Hereby, a pressurized fluid which expands rapidly as a result of depressurization is used to prepare the superhydrophobic surface, thereby facilitating the preparation of the surface. Moreover, the invention refers to an arrangement for preparing a superhydrophobic surface on a substrate, a superhydrophobic film prepared by the method of the invention, and a substrate having deposited thereon the superhydrophobic firm.
US08722140B2 Solar heat-reflective roofing granules, solar heat-reflective shingles, and process for producing the same
A process for preparing roofing granules includes forming kaolin clay into green granules and sintering the green granules at a temperature of at least 900 degrees Celsius to cure the green granules until the crystalline content of the sintered granules is at least ten percent as determined by x-ray diffraction.
US08722139B2 Transparent article
A method of producing a transparent article comprised of a transparent base substrate and having a thickness of at least 100 microns and a surface costing of a transparent resin wherein the resin is applied to the base substrate by means of a jet printer, preferably an ink jet printer. The transparent article may be a window for a display device, e.g. incorporated in a mobile telephone.
US08722138B2 Method of manufacturing glass substrate and information recording medium
In a method of manufacturing a glass substrate for an information recording medium including a step for chemically strengthening the glass substrate by contacting the glass substrate with chemical strengthening processing liquid containing chemical strengthening salt, concentration of Fe and Cr is 500 ppb or less in said chemical strengthening salt, respectively. The concentration may be detected by the use of an ICP (Inductively Coupled Plasma) emission spectrometry analyzing method or a fluorescent X-ray spectroscopy analyzing method.
US08722137B2 Hydrated water-absorption polymer containing resin composition, porous body and insulated wire using same, method of making the wire and coaxial cable
A hydrated water-absorption polymer containing resin composition includes a liquid cross-link curable resin composition, and a water-absorption polymer dispersed in the liquid cross-link curable resin composition. The water-absorption polymer is preliminarily hydrated and swollen. The water-absorption polymer before being hydrated and swollen includes an average particle diameter of not more than 10 μm. The water-absorption polymer includes an amount of water absorption of 10 to 100 g/g.
US08722134B2 Post-harvest treatment of fruits with an antifungal composition
The present invention relates to the treatment of wounds occurring from cutting bananas and pineapples from a tree with a composition containing natamycin and at least one phosphite containing compound.
US08722133B2 Method for production of orally rapidly disintegrating tablet comprising imidafenacin as active ingredient
The present invention herein provides an imidafenacin-containing orally rapidly disintegrating tablet which is excellent in the photostability.The present invention comprises the steps of: (A) granulating imidafenacin together with starch to thus give a granulated product having an imidafenacin concentration ranging from 0.001 to 3% by mass and a starch concentration ranging from 40 to 99.999% by mass; (B) covering the granulated product prepared in the step (A) with a non-cellulosic coating agent; and (C) blending the granulated product obtained in the preceding step (B) with an excipient and a disintegrating agent and then forming the resulting mixture into a tablet according to the compression molding technique.
US08722127B2 Bakery and pasta products comprising acidified chitosan
Bakery products and pasta with added chitosan are disclosed. The chitosan is addified with a biologically acceptable acid and added to pasta and baked products. Once the baked products and/or pasta are ingested, gastro-intestinal absorption of fats is limited even after cooking.
US08722126B2 Compositions for food, process for producing the same, and functional foods and drinks containing the same
Black currant anthocyanin-containing compositions for foods comprising 1 to 25% by weight of black currant anthocyanin on the basis of solid matters; a process for producing a black currant anthocyanin-containing composition for foods characterized by purifying and concentrating black currant juice employed as a starting material by using a charged reverse osmosis membrane; functional foods and drinks characterized by containing the above compositions for foods; and the above-described compositions for foods and the above-described functional foods and drinks having an effect of improving visual function, a function of improving blood fluidity, and/or a function of lowering blood pressure. The conventional black currant anthocyanin compositions have a low black currant anthocyanin content, strong acidity and poor stability, which makes them unsuitable as additives for foods and drinks. However, the production process according to the present invention makes it possible to provide black currant anthocyanin-containing compositions for foods which have a high black currant anthocyanin content, an adequate acidity, and a high stability and can be added to foods and drinks. Moreover, functional foods and drinks containing these compositions, which have an effect of improving visual function, a function of improving blood fluidity, or a function of lowering blood pressure, can be provided.
US08722124B2 Process of brewing tea leaves contained in a capsule
The invention concerns a process for the preparation of a beverage in a beverage machine with a capsule comprising an enclosure containing tea leaves comprising the steps of: a) introducing water in the capsule to submerge the tea leaves in the capsule enclosure, then b) introducing water at a soaking flow of at most 80 ml/min, then c) introducing water in the capsule until the required volume of beverage is delivered, wherein during at least one period of step b), water is introduced in the capsule at least once at a stirring flow superior the soaking flow to stir tea leaves.
US08722123B2 Antimicrobial composition and use as food treatment
Antimicrobial compositions are provided comprising a pharmaceutically acceptable organic acid and a pharmaceutically acceptable surfactant. This synergistic combination allows compositions to be formulated at low concentrations that have efficacy in reducing bacterial counts by greater than 3 log within 5 minutes of contact while preserving the organoleptic properties of treated foods, including fresh produce. Also provided are methods for the use of the compositions to reduce the microbial load on the surfaces of foodstuffs, processed food products, and the hard surfaces of food preparation machinery, tools, benches, and the like.
US08722122B2 Package integrity indicator for container closure
A resealable closure for packages is provided which has a package integrity feature. The closure includes a two-ply material having an inner film layer and an outer film layer, forming a top of container. The outer film layer has a sealing panel completely covering a first panel and a second panel of the inner film layer. The sealing panel is permanently attached to the first panel and is releasably affixed a portion of the inner film layer around the perimeter of the first panel to form an opening in the top when the sealing panel with affixed first panel is peeled back from the top. The sealing panel is resealable against the top to seal the opening when the sealing panel is moved back against the top. The package integrity feature comprises the second panel of the inner layer which separates from the sealing panel to indicate that the container has been previously opened.
US08722121B2 Candy holder and candy product including the same
A candy holder for receiving and securing an elongated candy therein is provided. The candy holder includes a handle portion defining an elongated cavity with a central axis. The handle portion has a plurality of protrusions extending toward the central axis and circumferentially around an inner surface of the handle portion. A top portion of the candy holder has a lip defining an opening. The opening receives the elongated candy that is dimensioned to correspond to a size of the opening. The lip and protrusions apply friction to a surface of the elongated candy when the elongated candy is inserted therein.
US08722116B2 Treating a bacteria-induced gastric disorder with a mixture having pomegranate and hydrogen peroxide
The present invention is directed to a method and a composition for producing and using a plant-based biocidal solution. The plant-based biocidal solution contains a bioactive material and a plant-based substance formed from the cellular material of a plant. The plant-based substance is capable of binding to the bioactive material. In some embodiments, the bioactive material is hydrogen peroxide. The hydrogen peroxide can be added exogenously or generated endogenously. In accordance with further embodiments, the plant-based biocidal solution can be applied to a target, thereby impairing the target. In some embodiments, the target can be a pathogen. In accordance with another embodiment, the plant-based substance of the plant-based biocidal solution can form a microscopic cluster, a complex, or an aggregate for providing sufficient bioactive material to overcome the defense mechanism of the target.
US08722115B2 Methods for improving health in animals
A method of improving health in an animal includes administering to the animal a nutritional supplement comprising an amino acid secretagogue composition, which stimulates the pituitary gland in the animal to produce growth hormone. The nutritional supplement may be administered orally. The nutritional supplement may comprise L-arginine hydrochloride, L-pyroglutamic acid, L-lysine hydrochloride, and cysteine. When desired, the nutritional supplement may consist essentially of L-arginine hydrochloride, L-pyroglutamic acid, L-lysine hydrochloride, N-acetyl-L-cysteine, L-glutamine, and schizonepeta powder.
US08722112B2 Method for prolonging the life of animals
A method for increasing the longevity of an old animal comprising administering to the animal a composition comprising one or more antioxidants in a total antioxidant amount sufficient to increase the longevity of the animal.
US08722110B2 Pharmaceutical composition for preventing or treating inflammatory diseases, allergic diseases or asthma, containing Diospyros blancoi A. DC. extract as active ingredient
Disclosed is a pharmaceutical composition for the prophylaxis and therapy of inflammatory diseases, allergic diseases, or asthma, comprising a velvet apple (Diospyros blancoi A. DC.) extract as an active ingredient. Having the inhibitory activity against the nuclear translocation of NF-κB, whose level is rapidly elevated in response to inflammatory stimuli, the velvet apple extract can suppress the production of NO and PGE2, the expression of iNOS and COX-2, and the release of IL-1β and TNF-α, and can significantly down regulate Th2-mediated IL-4 and IL-13 production. In addition, the extract was found to inhibit the activation of eosinophils in bronchoalveolar lavage fluid, and to suppress the secretion of immunoglobulins and chemokines in bronchoalveolar lavage fluid and blood, as measured by in vivo tests on an ovalbumin-induced asthma mouse model. Therefore, the extract can be used in the method for preventing or treating various inflammatory disorders, allergic diseases, or asthma.
US08722104B2 Composition containing organic substance having double bond with improved oxidative stability
To an organic substance having a double bond such as a polyunsaturated fatty acid was added an antioxidative component containing an antioxidative sesame component and ascorbic acid or an ascorbyl fatty acid ester.The above method provides a composition containing an organic substance having a double bond exhibiting enhanced oxidative stability. Particularly, it extremely improves oxidative stability of fat and oil which contains polyunsaturated fatty acid. General-purpose refined fish oil which is easy to handle can be provided for food, medicine or feed uses.
US08722100B2 Mineral trioxide aggregate (MTA) composition and use
The present application discloses a fast-setting mineral trioxide aggregate (MTA) with fluoride release for practical treatment of diseases in teeth and bone, e.g. for caries treatment and/or prevention. The cariostatic MTA contain calcia-silica-alumina cement with moderately increased tricalcium aluminate content allowing high calcium hydroxide release. The MTA composition support remineralization and biomineralization, and it is suitable for stimulation of hard tissue regeneration. MTA embodiments contain superplasticizer and nanosilicate for improved mechanical properties. The MTA compositions include optional radiocontrast and nano-enriched leachable fluorine, nitrate, strontium, and phosphate. The fast-setting MTA paste exhibits flow-to-clay-like consistency, which allows new practical applications including cavity lining, temporary restoration, bonding, and cementations in one MTA embodiment. The high calcium hydroxide and high fluoride release are suitable for caries prevention and treatment, and per se inhibition of dental symptoms.
US08722099B2 Porous bioceramic composition for bone repair
The present invention relates to a porous bioceramic composition for bone repair and method of fabrication of the same. 3D-scaffolds were fabricated with a novel micro- and macro-architecture. Porous scaffolds based on dextrin, dextran, gelatin and biomineral (CaCO3) powder were fabricated by heating and freeze-drying methods. Fabrication of different compositions of porous scaffolds (20, 30 wt % of gelatin, 20, 40 wt % dextrin, 30, 40, 50, 60 wt % dextran bounder with the constant quantity of CaCO3 50 g). The scaffolds properties were characterized by x-ray diffraction (XRD), differential scanning calorimetry (DSC), scanning electron microscopy (SEM) and compression tests.
US08722098B2 Ecklonia cava extracts for alleviating or preventing asthmatic reactions
A method of alleviating or preventing inflammation in an animal is provided. In concrete, the method comprises the step of administering to an animal a composition including an Ecklonia cava extract in an amount effective to suppress SOCS-3 expression in the animal to thereby alleviate or prevent inflammation in the animal.
US08722097B2 Oil-in-water method for making polymeric implants containing a hypotensive lipid
Biocompatible microparticles include an ophthalmically active cyclic lipid component and a biodegradable polymer that is effective, when placed into the subconjunctival space, in facilitating release of the cyclic lipid component into the anterior and posterior segments of an eye for an extended period of time. The cyclic lipid component can be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the cyclic lipid component can be encapsulated by the polymeric component. The present microparticles include oil-in-water emulsified microparticles. The subconjunctivally administered microparticles can be used to treat or to reduce at least one symptom of an ocular condition, such as glaucoma or age related macular degeneration.
US08722093B2 Policosanol nanoparticles
The present invention provides nanoparticulate policosanol, formulations including these particles, as a well as methods of using the particles and formulations for treatment and prophylaxis of various diseases and conditions.
US08722090B2 Granulate comprising an oily substance, corresponding production method and tablet
The invention relates to a process for the preparation of granules comprising an oily substance. It relates also to granules for a pharmaceutical formulation and to a tablet as a product of further processing.
US08722083B2 Fenofibrate formulation
Various fenofibrate compositions include a plurality of first granules having a high bioavailability in vivo, and a plurality of second granules having a low bioavailability in vivo. The first granules may comprise fenofibrate, from 0.3% to 10% by weight of the first granules of a first surfactant, and a first water soluble or water dispersible cellulose derivative, and the second granules may comprise fenofibrate, from 0% to 0.25% by weight of the second granules of a second surfactant, and a second water soluble or water dispersible cellulose derivative.
US08722079B2 Methods for treating conditions such as dystonia and post-stroke spasticity with clonidine
Effective treatments of dystonia and/or post-stroke spasticity for extended periods of time are provided. Through the administration of an effective amount of clonidine at or near a target site, one can relieve dystonia and/or post-stroke spasticity caused by diverse sources. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least five days. In some embodiments, the relief can be for at least twenty-five days, at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.
US08722078B2 Polymeric device for controlled release of active agents
Polymeric devices for controlled release of an active agent of interest are provided. The active agent is provided within a biodegradable polymer system to supply a polymeric device for controlled release of the active agent. The polymer system is a copolymer or a polymer blend comprising a hydrophobic component and a hydrophilic component, and the polymer system does not form a hydrogel when contacted with, or immersed in an aqueous system, for example when the device is implanted in a subject. When the device is administered to a subject, for example, when it is implanted, the device releases the active agent in a controlled fashion without a lag period, or with a minimal lag period. Methods for producing the polymeric devices are also provided, as are methods of using the polymeric devices to provide for controlled release of an active agent in a subject.
US08722076B2 Photochrome- or near IR dye-coupled polymeric matrices for medical articles
The invention provides polymers comprising pendent photochrome or near IR dye groups, as well as polymeric matrices made from these polymers, which can be used as or in association with a medical article. The polymers can be synthesized using methods that facilitate the preparation of medical articles having good biocompatibility. Exemplary polymeric matrices are in the form of lubricious coatings on medical devices, such as catheters. Visualization by irradiation of the photochrome or near IR dye can improve detection of the polymeric matrix on a device or in the body. This, in turn can improve aspects of a medical procedure, such as device insertion or matrix formation, as well as being useful for assessing the quality of the matrix.
US08722074B2 Medical devices containing radiation resistant polymers
The present invention relates generally to radiation-resistant medical devices which contain polymer regions for release of therapeutic agents. The present invention also relates to radiation-resistant copolymer materials for use in connection with insertable or implantable medical devices. The radiation-sterilized medical device comprises (a) a release region and (b) at least one therapeutic agent and the release region comprises a phenoxy resin block.
US08722065B2 Lidocaine tape preparation
The present invention discloses a novel tape preparation containing lidocaine at a high concentration. A tape preparation containing lidocaine at a high content, which has a lidocaine content of 10 w/w % or more, can be produced by using a lactic acid salt of lidocaine, while preventing the precipitation of a crystal of lidocaine.
US08722060B2 Method of treating vertigo
The invention is a method for reducing the symptoms of vertigo. The method is performed by delivering a therapeutically effective amount of presynaptic neurotoxin, such as Botulinum Toxin A, in a pharmaceutically safe form to suitable locations around the head and neck.
US08722059B2 Multi plasmid system for the production of influenza virus
Vectors and methods for the production of influenza viruses suitable as recombinant influenza vaccines in cell culture are provided. Bi-directional expression vectors for use in a multi-plasmid influenza virus expression system are provided.
US08722057B2 Method for producing β-carotene rich Dunaliella powder
In a step of producing a powder product of the alga belonging to the genus Dunaliella, a pH adjusting step is included in which an alga belonging to the genus Dunaliella is allowed to be in a basic state of pH 9.5 or higher. According to the method, it is possible to provide dried Dunaliella powder containing β-carotene at a high content by suppressing degradation of β-carotene as an active ingredient while decreasing each of the total pheophorbide amount and the existing pheophorbide amount to a predetermined value or less, even if the total pheophorbide amount and the existing pheophorbide amount of the cultured algae belonging to the genus Dunaliella are higher in summer.
US08722056B2 Methods for making and compositions comprising fermentation products of cordyceps sinensis
The present invention relates to novel and non-obvious methods and media for preparing fermentation products of Cordyceps sinensis. The present invention also relates to novel and non-obvious compositions comprising fermentation products of Cordyceps sinensis produced by the methods of the invention or obtained from other sources. The present invention also relates to novel and non-obvious methods of treating patients by administering the compositions of the invention. In one embodiment, the Cordyceps sinensis mycelia is Paecilomyces hepiali mycelia. In another embodiment the compositions of the invention are used to treat patients infected with hepatitis C.
US08722055B2 Synthetic Streptococcus pneumoniae vaccine
Compositions and methods for preventing and treating pneumococcal infections are provided. Compositions include novel polypeptides comprising an amino acid sequence corresponding to the R2i or R22 domain of CbpA or a consensus sequence of one of these domains, and variants and fragments thereof, wherein the polypeptide is stabilized in a desired conformation, particularly a loop conformation. The polypeptides of the invention may be engineered to comprise a first and a second cysteine residue, thereby resulting in the formation of a disulfide bond that stabilizes the polypeptide in the desired conformation. Alternatively, a polypeptide of the invention may be modified to create a synthetic linkage between a first and second amino acid residue present within the polypeptide, wherein the synthetic linkage stabilizes the polypeptide in the desired conformation. The polypeptides of the invention may further comprise an amino acid sequence for a T cell epitope. Compositions further include isolated nucleic acid molecules that encode the polypeptides of the invention, immunogenic compositions and vaccines comprising the disclosed polypeptides, and antibodies specific for these polypeptides.
US08722054B2 Compositions and methods for the treatment or prevention of hepatitis B virus infection
Disclosed are yeast-based immunotherapeutic compositions, hepatitis B virus (HBV) antigens, and fusion proteins for the treatment and/or prevention of HBV infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions, HBV antigens, and fusion proteins for the prophylactic and/or therapeutic treatment of HBV and/or symptoms thereof.
US08722053B2 IgE CH3 peptide vaccine
The present invention relates to the provision of novel immunogens comprising an antigenic IgE peptide preferably linked to an immunogenic carrier, compositions comprising the immunogens, and methods for the prevention, treatment or alleviation of IgE-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine.
US08722052B2 Vaccinia virus protein A46 peptide and use thereof
A peptide for inhibiting Toll-like receptor 4 (TLR4) signalling comprising the amino acid sequence of SEQ ID NO. 4, SEQ ID NO 55, SEQ ID NO 68, SEQ ID NO. 69, SEQ ID NO 70, SEQ ID NO 71, SEQ ID NO 72, SEQ ID NO 79, SEQ ID NO 82, SEQ ID NO 85, SEQ ID NO 88, SEQ ID NO 91, SEQ ID NO 94, SEQ ID NO 97, SEQ ID NO 100, SEQ ID NO 103, SEQ ID NO 106, SEQ ID NO 109, SEQ ID NO 112, or SEQ ID NO 115. The peptide may comprise a delivery sequence such as a cationic peptide.
US08722051B2 Tweak receptor
The present invention provides the TWEAK receptor and methods for identifying and using agonists and antagonists of the TWEAK receptor. In particular, the invention provides methods of screening for agonists and antagonists and for treating diseases or conditions mediated by angiogenesis, such as solid tumors and vascular deficiencies of cardiac or peripheral tissue.
US08722048B2 T-cell receptor capable of recognising an antigen from cytomegalovirus
The present invention provides a T-cell receptor (TCR) which binds to a peptide from the cytomegalovirus (CMV) phosphoprotein pp65 having the amino acid sequence NLVPMVATV (SEQ ID No. 1) when presented by a major histocompatability complex (MHC) molecule. The present invention also provides a nucleotide sequence encoding such a TCR, a vector comprising such a nucleotide sequence and its use to produce a CMV-specific T-cell. The present invention also provides the use of CMV-specific T-cell for cellular immunotherapy.
US08722047B2 Humanized anti-HLA-DR antibodies
The present invention concerns compositions and methods of use of humanized anti-HLA-DR antibodies. In preferred embodiments, the antibodies induce apoptosis and inhibit proliferation of lymphoma cells without inducing CDC or ADCC. In more preferred embodiments, the humanized anti-HLA-DR antibodies bind to the same epitope of HLA-DR as, or compete for binding to HLA-DR with, a murine L243 antibody. Most preferably, the humanized anti-HLA-DR antibody exhibits a higher affinity for HLA-DR than the parental murine antibody. The humanized HLA-DR antibody is of use for therapy of various diseases such as cancer, autoimmune disease or immune dysregulatory function, and is of particular use for therapy of B cell lymphomas and leukemias. In most preferred embodiments, the humanized anti-HLA-DR antibody is capable of inducing at least partial remission of lymphomas that are resistant to other B cell antibodies, such as rituximab.
US08722046B2 Human monoclonal antibodies protective against bubonic plague
In this application are described fully human monoclonal antibodies which specifically recognize F1 or V antigen of Y. pestis and epitopes recognized by these monoclonal antibodies. Also provided are mixtures of antibodies of the present invention, as well as methods of using individual antibodies or mixtures thereof for the detection, prevention, and/or therapeutical treatment of plague infections in vitro and in vivo.
US08722045B2 Cell and therapeutical and diagnostical methods based thereon
The invention relates to a novel cell derived from the human body, where said cell comprises a Clever-1 receptor; to a method for affecting the immune system of an individual and for treatment of diseases or conditions related to the function of the immune system and to methods for screening of cancer patients that may respond to an anti-Clever-1 therapy or for diagnosing of a pregnancy complication or for estimating the risk of such complication in a pregnant woman.
US08722044B2 Human tissue factor antibody and uses thereof
The invention relates to a humanized form of an antibody capable of preventing tissue factor (coagulation factor F3) signaling but which does not interfere with Factor VII binding or FX binding to tissue factor and does not prolong coagulation time. The antibody of the invention is useful in treating conditions, such as tumor progression, in which the associated cells express tissue factor and tissue factor signaling occurs.
US08722043B2 Induction of p53 expression by neutralization of neuropilin-2 for the treatment of cancers
The present invention relates to the use of anti-human neuropilin-2 antibodies, or of ligands of human neuropilin-2 derived from these antibodies, for obtaining a medicament intended to increase p53 expression and to induce tumor cell apoptosis in the context of an anticancer treatment.
US08722041B2 Anti-human equilibrative nucleoside transporter 1 (hENT1) antibodies and methods of use thereof
This invention provides monoclonal antibodies that recognize hENT1. The invention further provides methods of using such monoclonal antibodies as a therapeutic, diagnostic, and/or prophylactic in disorders associated with aberrant hENT1 expression and/or activity.
US08722040B2 Site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites
The teachings provided herein generally relate to site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites. More particularly, the systems taught here include a phenolic compound bound to a reactive oxygen species, wherein the phenolic compound and the reactive oxygen species react at a target area in the presence of an oxidoreductase enzyme.
US08722037B2 X-ray visible drug delivery device
The subject invention provides an X-ray visible drug delivery device for subdermal administration of a contraceptive or hormone replacement therapy.
US08722035B2 Formulations including digestive enzymes, polysorbate-based surfactants and probiotics
Disclosed are formulations for enhancing the in vivo colonization of probiotic microorganisms that include digestive enzymes and probiotic microorganisms, and polysorbate surfactants. The enzymes include lactogenic enzyme formulations that promote growth of Lactobacillus probiotics, bifidogenic enzyme formulations that promote growth of Bifidobacterium probiotics and combination formulations that benefit both types of probiotics. It has been discovered that certain polysorbate surfactants, including polysorbate-60 and polysorbate-80, further promote probiotic microorganism growth, when used with the enzyme formulations. The formulations are preferably compounded as dry powders, to avoid water reaction with the enzymes in blended formulations. Such formulations can be contained in capsules, tablets, packets or bottles and administered orally, either sequentially or in one combined formulation.
US08722033B2 Human IL-23 antigen binding proteins
Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
US08722032B2 Thiol-selective water-soluble polymer derivatives
The present invention provides water-soluble, polymer derivatives having a thiol-selective terminus suitable for selective coupling to thiol groups, such as those contained in the cysteine residues of proteins, as well as methods for preparing the water-soluble, polymer derivatives having a thiol-selective terminus.
US08722031B2 Animal litter deodorizing composition and method
There is provided an aqueous liquid deodorizing composition for animal lifter and a method of deodorizing animal litter by contacting the litter with the composition by spraying. The composition comprises a crusting inhibitor.
US08722030B2 Composite vaccine adjuvant
The invention provides a composite vaccine adjuvant, which is comprised of sodium ferulate and zinc hydroxide in a mass ratio of 10:1˜50:1. When the composite vaccine adjuvant and vaccine used in combination, the humoral immunity response is enhanced effectively, the enhanced effects is similar with aluminum adjuvant, superior to single sodium ferulate adjuvant and single zinc hydroxide adjuvant. It is not only atoxic, safety, but also reliable in the range of immune dose. The composite vaccine adjuvant with easily obtained and commercially available raw materials, is low cost, stable performance and simple preparation technology, which can be used as an adjuvant of hepatitis B vaccine, gene-engineered vaccine, virus vaccine and so on.
US08722024B2 Ester gels, methods of manufacture, and uses thereof
Gels of isopropyl esters of fatty alcohols that include a dimethyl/methylhydrogensiloxane copolymer, a silanol-terminated PDMS or an ethenyl-terminated PDMS, and a hydride functional siloxane. Also provided are methods for making the gels and articles containing them.
US08722022B2 Chewing gum tablet and method of dosing pharmaceutically active ingredients in such chewing gum tablet
A method of dosing pharmaceutically active ingredients in a compressed chewing gum tablet includes the steps of: providing one or more pharmaceutically active ingredients, mixing a chewing gum composition including the one or more pharmaceutically active ingredients and chewing gum granules, the chewing gum granules including gum base, and dosing the chewing gum composition to obtain a desired weight of the chewing gum composition and thereby obtaining a desired dose of the pharmaceutically active ingredient in the chewing gum tablet.
US08722019B2 P97 fragments with transfer activity
The present invention is related to fragments of human melanotransferrin (p97). In particular, this invention relates to treatment of diseases through the introduction of the melanotransferrin fragment conjugated to a therapeutic or diagnostic agent to a subject.
US08722016B2 Methods of identifying xenohormetic phenotypes and agents
Methods of identifying a xenohormetic induced phenotype in an organism are provided. Also provided are methods if using organisms having a known xenohormetically induced phenotype in a number of different applications, such as the identification of xenohormetic agents and the generation of chemical entities and foodstuffs under specific conditions of production governed by xenohormetic effects.
US08722015B2 Compositions and methods for treatment of angiogenesis-associated ocular disorders
The invention provides methods and compositions for identifying and quantifying pathological changes on the retina.
US08722014B2 1 H-[1, 2, 3] triazole substituted amino acids and uses thereof
Tracers for cationic amino acid transport systems and methods of synthesis are disclosed, including compounds comprising a 1H-[1,2,3]triazole moiety. Further disclosed are uses of the analogues, including in vivo imaging of tumors by Positron emission tomography (PET) or Single Photon Emission Computed Tomography (SPECT).
US08722012B2 Method for preventing nasolacrimal duct obstruction
The invention is directed to a method for preventing nasolacrimal duct obstruction (NLDO) in a patient receiving high dose radioactive iodine for treatment of cancer. The method includes administering an effective amount of perchlorate anion to the eyes of the patient.
US08722011B2 Method of producing hydrogen from ammonia
In a method by which hydrogen supplied as a combustion aid to an ammonia combustion engine is produced from ammonia, the filling amount of a decomposition catalyst in an ammonia decomposition apparatus is reduced. The method includes an ammonia decomposition apparatus that produces hydrogen as a combustion aid and an ammonia oxidation apparatus that allows a part of introduced ammonia to react with oxygen for combustion by action of an oxidation catalyst in order to supply the heat needed for the ammonia decomposition reaction, wherein the amount of ammonia and the amount of air introduced into the oxidation apparatus are controlled in accordance with the entrance temperature of an ammonia oxidation catalyst layer, so as to set the ammonia decomposition ratio in the ammonia decomposition apparatus to be 40 to 60% at all times.
US08722010B1 Coproduction of oxygen, hydrogen, and nitrogen using ion transport membranes
A method for the coproduction of oxygen, hydrogen and nitrogen using an ion transport membrane is provided. This method includes separating a compressed, hot air stream in an ion transport membrane, thereby producing a product oxygen stream and a hot nitrogen rich stream; utilizing at least a portion of the hot nitrogen rich stream as a heat source for reforming a hydrocarbons stream, thereby producing a syngas stream and a warm product nitrogen stream; and separating the syngas stream into a product hydrogen stream and a carbon dioxide rich stream.
US08722009B2 Nanocrystalline copper oxide and method for the production thereof
A nanocrystalline supported or unsupported copper oxide with a residual carbon content of <10% and a BET surface area >95 m2/g. Further, a method for the production of a supported, or unsupported nanocrystalline copper oxide is disclosed, as well as the use thereof in catalysis, in particular in the steam reforming of methanol or in the hydrogenation of esters.
US08722008B2 Method for upgrade-processing carbon black produced by performing a pyrolysis process on waste tires
Disclosed is a method for upgrade-processing carbon black produced by performing a pyrolysis on waste tires and, more particularly to, a method of upgrading carbon black which includes removing iron wires and fibers from carbon black produced by performing a pyrolysis on waste tires with a magnetic separator and a gravity separator and then subjecting the carbon black to micronization, heating, and acid treatment to upgrade the carbon black. The method for upgrade-processing carbon black produced by performing a pyrolysis on waste tires includes producing an inorganic salt by treating carbon black produced by performing a pyrolysis on waste tires with an acid solution to produce an inorganic salt from an inorganic substance contained in the carbon black.
US08722007B2 Method for producing carbon nanomaterials produced from heavy oil
The present invention relates to a method for producing carbon nanoparticles employing heavy petroleum as a carbon precursor, obtained from decant oil, by using the technique of chemical vapor deposition (CVD), and optionally by using an organometallic catalyst that is soluble in the carbon precursor. The main feature of the method according to the invention is that the precursor is vaporized in a controlled manner so as to provide pulses of vapor of constant composition inside a tubular furnace which can be arranged in a vertical position for the continuous production of nanomaterials or in a horizontal position for batch production.
US08722005B1 Synthesis of hydrogen bis(fluorosulfonyl)imide
The invention provides a method for producing hydrogen bis(fluorosulfonyl)imide (HFSI) by reacting hydrogen bis(halosulfonyl)imide (HXSI) with hydrogen fluoride, where each X is independently a nonfluoro-halide, such as Cl, Br, or I.