Document | Document Title |
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US08723399B2 |
Tunable ultrasound transducers
A variety of micromachined structures are disclosed for use in DC-tunable ultrasound transducers. |
US08723397B2 |
Dynamically adjusting piezoelectric current sensors
Provided are various embodiments of an adjustment circuit, having a base layer and a piezoelectric layer juxtaposed relative to the base layer and including a first electrode such that when the piezoelectric layer is stressed a polarization charge appears between the base layer and one side of the piezoelectric layer and an opposite polarization charge appears on an opposite side of the piezoelectric layer. |
US08723395B2 |
Surface acoustic wave device, electronic apparatus, and sensor apparatus
A SAW device has an IDT which is provided on the principal surface of a quartz crystal substrate having Euler angles (−1.5°≦φ≦1.5°, 117°≦θ≦142°, 42.79≦|ψ|≦49.57°) and excites a SAW in a stopband upper end mode, and a pair of reflectors which are arranged on both sides of the IDT. Inter-electrode-finger grooves are recessed between the electrode fingers of the IDT, and inter-conductor-strip grooves are recessed between the conductor strips of the reflectors. A first direction (X′ axis) perpendicular to the electrode fingers and the conductor strips intersects the electrical axis (X axis) of the quartz crystal substrate at an angle ψ. At least a part of the IDT and the reflectors are arranged in a second direction intersecting the first direction at an angle α of 1.0°≦α≦2.75°. An excellent frequency-temperature characteristic and a high Q value in an operation temperature range are realized simultaneously. |
US08723394B2 |
Surface acoustic wave device, electronic apparatus, and sensor apparatus
A SAW device has an IDT which is provided in the principal surface of a quartz crystal substrate having Euler angles (−1.5°≦φ≦1.5°, 117°≦θ≦142°, |ψ|≠90°×n (where n=0, 1, 2, 3)) and excites a Rayleigh wave (wavelength: λ) in a stopband upper end mode. Inter-electrode-finger grooves are recessed between the electrode fingers of the IDT. The depth G of the inter-electrode-finger grooves is 0.01λ≦G≦0.07λ, and an electrode finger thickness H and an IDT line occupancy η satisfy a predetermined relationship. Thus, a frequency-temperature characteristic constantly has an inflection point between a maximum value and a minimum value in an operation temperature range, thereby suppressing a fluctuation in an inflection-point temperature due to a manufacturing variation in the IDT line occupancy η. |
US08723392B2 |
Saw filter having planar barrier layer and method of making
Disclosed herein is a surface acoustic wave (SAW) filter and method of making the same. The SAW filter includes a piezoelectric substrate; a planar barrier layer disposed above the piezoelectric substrate, and at least one conductor buried in the piezoelectric substrate and the planar barrier layer. |
US08723389B2 |
Sheet plate for DC motor
Disclosed is a sheet plate for a DC motor, in which a brush holder manufactured as a separate member is coupled to the sheet plate of the DC motor, thus effectively guiding movement of a brush and a pigtail, and affording good space utilization, the sheet plate including a brush holder taking a shape of a rectangular pillar to hold the brush and coupled to a first surface of the sheet plate, wherein the brush holder includes an opening formed in an upper surface of the brush holder in a longitudinal direction thereof to allow a pigtail to be taken out through the opening, and a cover portion provided above the opening to be spaced apart therefrom and formed as a plate that is long in a diametric direction, so that the pigtail is bent in a circumferential direction by the cover portion when being taken out. |
US08723382B2 |
Electromagnetic motor-generator unit
An electromagnetic motor-generator unit (MGU) includes a motor and a generator. The motor includes permanent magnets disposed on a rotor hub, a rotor shaft connected to the hub, and stator brackets arranged in a ring. Each of the brackets forms a generally U-shaped profile. The side walls and base of each bracket includes a post, around which is wound a coil. A first chassis circumscribes the brackets, with the base of each bracket connected to an inner wall of the first chassis. The generator includes insulating rotor plates each having equally spaced teeth. The plates are connected to the shaft. Wedge-shaped permanent magnets are stacked within gaps of the plates. A second chassis circumscribes the plates and the wedge-shaped permanent magnets, and includes coils disposed on an inner face of the second chassis. The coils are connectable to a battery pack to selectively recharge the battery pack. |
US08723381B2 |
Electric motor
A brush holder is placed between a yoke housing and a gear housing and includes a holder member and a base member. The holder member is installed to an opening of the yoke housing and holds a plurality of brushes. The base member is installed to the holder member and includes a connector configured to connect with an external connector to receive an electric power. An output side end part of the yoke housing has a flange portion, through which the gear housing is fixed to the yoke housing. The holder member includes a contact portion that contacts an opening end portion of the yoke housing in an axial direction of a rotatable shaft. The contact portion is axially spaced from the base member by an axial gap. |
US08723380B2 |
Starter motor including a conductor mounting element
A starter motor including a frame having a terminal mounting portion, and a field fixedly mounted relative to the frame. An armature is rotatably supported relative to the field. A conductor having a terminal mounting section is electrically connected to one of the field and the armature. A terminal extends through the terminal section of the conductor and the terminal mounting portion of the frame. The terminal includes a plurality of threads. A conductor mounting element threadably engages with the plurality of threads. The conductor mounting element is configured to form a threaded clamped connection that establishes a solid metal compressive stack up connection between the conductor and the terminal. |
US08723375B2 |
Linear actuator
A linear actuator includes a coil portion and a shaft portion. The coil portion includes a plurality of coils respectively applied with AC currents having different phases from one another. The shaft portion passes through an inside of the plurality of coils. The shaft portion includes: a plurality of permanent magnets and a plurality of intermediate members. The plurality of permanent magnets is arranged along a central axis C such that opposite magnetization directions face to each other in a direction of the central axis C. Each of the plurality of intermediate members is arranged between adjacent two of the plurality of permanent magnets. A saturation magnetic flux density of each of the plurality of intermediate members is higher than a saturation magnetic flux density of each of the plurality of permanent magnets. |
US08723367B2 |
Power supply system
In a power supply system, reducing influence of a noise etc., optimal electric power is supplied corresponding to power consumption of a receiving side load, and power consumption is decreased greatly. When a potential difference detector 12 detects that a power supply voltage of the receiving side load is decreased lower than a lower limit voltage threshold or increased higher than an upper limit voltage threshold, a burst interval setting unit sets up a burst signal of a pulse width corresponding to the detection result. A burst signal generator generates a burst signal based on the setup, and excites a control primary inductor. A burst signal detector generates a pulse signal in response to electromotive force of a control secondary inductor. A pulse width controller determines increase or decrease of the voltage value of the receiving side load from a no-signal period of a pulse signal, measured by a no-signal period measuring unit, and modifies and outputs a signal outputted by a alternating current generator so as to change a period or the number of times to excite a power primary inductor. |
US08723366B2 |
Wireless energy transfer resonator enclosures
Described herein are improved configurations for a resonator enclosure for wireless high power transfer that includes a support plate, a sheet of good conductor positioned on one side of the support plate, a separator piece for maintaining a separation distance between the resonator and the sheet of good conductor, and a cover of a non-lossy material covering the resonator, the separator, the sheet of good conductor and attached to the support plate, wherein the size of the sheet of good conductor is larger than the size of the resonator. |
US08723364B2 |
Uninterruptible power supply having integrated charge/discharge circuit
An uninterruptible power supply includes an AC-to-DC converting circuit, an energy storage unit, a first path-switching circuit, a second path-switching circuit, an integrated charge/discharge circuit and an operating control unit. If the input voltage is abnormal, the input terminal and the output terminal of the integrated charge/discharge circuit are respectively connected to the energy storage unit and the power supply output terminal, so that electric energy stored in the energy storage unit is transmitted to the power supply output terminal through the integrated charge/discharge circuit. Whereas, if the input voltage is normal, the input terminal and the output terminal of the integrated charge/discharge circuit are respectively connected to the power supply output terminal and the energy storage unit, so that the energy storage unit is charged by the integrated charge/discharge circuit. |
US08723361B2 |
Automatic transfer switch having an interlock arrangement
An automatic transfer switch to automatically electrically connect an electrical panel to a second power source, e.g., an electric generator, during interruption or failure of a first power source, e.g., a utility power supply, includes a powered interlock arrangement that is operative to prevent the electrical panel from being electrically connected to both power sources simultaneously. |
US08723357B2 |
Power supply having low quiescent consumption
Electronic circuitry and methods are provided. Electrical energy is coupled to a transformer by way of line filter of a power supply. A clipper circuit limits the alternating-current voltage applied to the primary side. A voltage tripler receives output from the secondary side of the transformer and a resulting voltage is coupled to a voltage regulator. At least one regulated direct-current voltage is output to a load and is maintained while a current pulse is applied to a predetermined device. The electronic circuitry conforms to pending power conservation requirements for computers and other equipment. |
US08723356B2 |
Discharge device for vehicle
A power control unit (PCU) case accommodates an electric circuit of a PCU, which includes a first capacitor and is operated by electricity supply from a storage battery. In the electric circuit, a first bus bar is connected to a part in the vicinity of the anode of the first capacitor, and a second bus bar is connected to a part in the vicinity of the cathode of the first capacitor. A discharge mechanism is formed by connecting in series a switch activated by an explosive actuator and a discharging resistor. The discharge mechanism is integrally fixed to the PCU case. When a collision of the vehicle is detected, the discharge mechanism short-circuits the first bus bar and the second bus bar with each other through the activation of the switch. Accordingly, the discharge mechanism is connected in parallel with the first capacitor, so that the discharging resistor discharges the first capacitor. |
US08723352B2 |
Systems for optimizing wave energy for renewable energy generation
A system for optimizing wave energy for renewable energy generation in onshore and offshore platforms is disclosed. In certain exemplary embodiments, wave energy from waves in an onshore platform enters or exits an air-tight chamber causing the air within the chamber to vent in or out via air-vents, and through the unidirectional turbine blades. The turbine rotates in a single direction causing an attached low speed axle to rotate as well. The low speed axle couples to a high speed axle via a step-up gearbox increasing the angular velocity of the axle. The high speed axle couples to a pump for suction of momentum transfer fluid from a tank and distribution of the fluid to a series of parallel evenly spaced, horizontal generator turbines, each with a differential pressure valve for differential inlet. The generator turbines connect to an AC or DC generator for power generation. |
US08723351B2 |
Multi-mode wave energy converter devices and systems
A wave energy converter (WEC) system includes WEC devices which can function to produce useful energy (power) efficiently in response to heave motion and/or pitch motion and/or roll motion. Pitch responsive devices are deployed around the outer periphery of a container and one (or more) heave responsive device is located about the center of the container. The pitch responsive devices may be of the type defined as PDWECs which include two reaction masses which are primarily operable in response to pitching motion or they may be of the type which includes one reaction mass operable in response to pitch and/or heave motion. |
US08723348B2 |
Battery assembly with kinetic energy-based recharging
A mobile electronic device configured to recharge when oscillated. The electronic device includes a housing with a battery compartment and a battery assembly positioned within the battery compartment. The battery assembly includes a rechargeable storage battery connected to device's battery contacts. The battery assembly includes a charging assembly connected to the rechargeable storage battery, and the charging assembly provides a kinetic energy-based generator operating during the oscillating motion of the electronic device to output electrical current to the rechargeable storage battery. The generator includes: (a) a barrel; (b) a permanent magnet positioned in an elongated chamber of the barrel and sliding within the chamber during movement of the device; and (c) a coil of conductive wire wrapped around an outer surface of the barrel. The chamber, generator magnet, and barrel outer surface receiving the coil all may be non-circular in cross sectional shape or non-cylindrical to improve kinetic energy harvesting. |
US08723347B2 |
Energy storage system utilizing compressed gas
An energy storage and recovery system employs air compressed utilizing power from an operating wind turbine. This compressed air is stored within one or more chambers of a structure supporting the wind turbine above the ground. By functioning as both a physical support and as a vessel for storing compressed air, the relative contribution of the support structure to the overall cost of the energy storage and recovery system may be reduced, thereby improving economic realization for the combined turbine/support apparatus. In certain embodiments, expansion forces of the compressed air stored within the chamber, may be relied upon to augment the physical stability of a support structure, further reducing material costs of the support structure. |
US08723343B2 |
Sensor with energy-harvesting device
In some embodiments of the present disclosure, a sensor comprises a substrate, a sensor element and an energy-harvesting device. The sensor element comprises a plate, and the plate is moveable with respect to the substrate. The energy-harvesting device is formed on the plate of the sensor element. |
US08723336B2 |
Semiconductor light emitting device and method for manufacturing same
According to an embodiment, a semiconductor light emitting device includes a light emitting body including a semiconductor light emitting layer, a support substrate supporting the light emitting body, and a bonding layer provided between the light emitting body and the support substrate, the bonding layer bonding the light emitting body and the support substrate together. The device also includes a first barrier metal layer provided between the light emitting body and the bonding layer, and an electrode provided between the light emitting body and the first barrier metal layer. The first barrier layer includes a first layer made of nickel and a second layer made of a metal having a smaller linear expansion coefficient than nickel, and the first layer and the second layer are alternately disposed in a multiple-layer structure. The electrode is electrically connected to the light emitting body. |
US08723335B2 |
Semiconductor circuit structure and method of forming the same using a capping layer
A semiconductor structure includes an interconnect region, and a material transfer region coupled to the interconnect region through a bonding interface. The semiconductor structure includes a capping layer sidewall portion which extends annularly around the material transfer region and covers the bonding interface. The capping layer sidewall portion restricts the flow of debris from the bonding interface. |
US08723332B2 |
Electrically interconnected stacked die assemblies
In die stack assembly configurations successive die in the stack are offset at a die edge at which die pads are situated, and the die are interconnected by electrically conductive traces. In some embodiments the electrically conductive traces are formed of an electrically conductive polymer. An electrically insulative conformal coating is provided having openings at die pads that are electrically connected. |
US08723331B2 |
Semiconductor device
Certain embodiments provide a semiconductor device including a first line, a second line, and a sacrificial line. The second line is connected to the first line, and has a narrower linewidth than the first line. The sacrificial line is a wiring having its one end connected to the first line, and its another end as an open end. Further, the sacrificial line at least partially has a portion with a narrower linewidth than the second line. |
US08723330B2 |
Protective layer for protecting TSV tips during thermo-compressive bonding
A method of protecting through substrate via (TSV) die from bonding damage includes providing a substrate including a plurality of TSV die having a topside including active circuitry, a bottomside, and a plurality of TSVs that include an inner metal core that reaches from the topside to protruding TSV tips that extend out from the bottomside. A protective layer is formed on or applied to the bottomside of the TSV die including between and over the protruding TSV tips. The TSV die is bonded with its topside down onto a workpiece having a workpiece surface and its bottomside up and in contact with a bond head. The protective layer reduces damage from the bonding process including warpage of the TSV die by preventing the bond head from making direct contact to the protruding TSV tips. |
US08723327B2 |
Microelectronic package with stacked microelectronic units and method for manufacture thereof
A microelectronic package may include a first microelectronic unit including a semiconductor chip having first chip contacts, an encapsulant contacting an edge of the semiconductor chip, and first unit contacts exposed at a surface of the encapsulant and electrically connected with the first chip contacts. The package may include a second microelectronic unit including a semiconductor chip having second chip contacts at a surface thereof, and an encapsulant contacting an edge of the chip of the second unit and having a surface extending away from the edge. The surfaces of the chip and the encapsulant of the second unit define a face of the second unit. Package terminals at the face may be electrically connected with the first unit contacts through bond wires electrically connected with the first unit contacts, and the second chip contacts through metallized vias and traces formed in contact with the second chip contacts. |
US08723326B2 |
Semiconductor structures including tight pitch contacts
Methods of fabricating semiconductor structures incorporating tight pitch contacts aligned with active area features and of simultaneously fabricating self-aligned tight pitch contacts and conductive lines using various techniques for defining patterns having sublithographic dimensions. Semiconductor structures having tight pitch contacts aligned with active area features and, optionally, aligned conductive lines are also disclosed, as are semiconductor structures with tight pitch contact holes and aligned trenches for conductive lines. |
US08723313B2 |
Semiconductor package structure and method for manufacturing the same
A semiconductor package structure and a method for manufacturing the same are provided, in which a semiconductor die is disposed in a spacer structure for packaging, and a connection pad, a first metallic layer, an insulating layer, a wiring layer, a pin base, a conductive via and a metallic bump are formed on the semiconductor die, wherein the wiring layer can be formed as a single layer or multiple layers, and the connection pad is electrically connected with an outer pin. Moreover, the positioning structures are also formed to overcome the conventional misalignment problems caused by the thermal expansion and the cooling contraction. The alignment of the conductive via with the connection pad can be more accurately achieved, which ensures that the connection pad is reliably connected with the outer pin. |
US08723301B2 |
Semiconductor package and system
A semiconductor package includes a package board, a pellet provided over the package board, and a protection member covering the package board and the pellet and including a hole penetrating the protection member. |
US08723298B2 |
Lead, wiring member, package component, metal component with resin, resin-encapsulated semiconductor device, and methods for producing the same
The present invention aims to make possible facile removal of resin burrs without the risk of damaging resin body covering a wiring lead in a semiconductor device. In detail, the semiconductor device 10 has a structure in which a semiconductor element is mounted on the wiring lead 10, the wiring lead 10 including a metal plate with metal coating applied to the outer surface thereof. The peripheral region 15 of the wiring lead 11 is covered with an organic coating including purine skeleton compounds. The organic coating is formed through the self-assembling of functional organic compounds each having a structure in which a purine skeleton has at an end thereof a functional group having a metal bonding property. |
US08723297B2 |
Memory device
In a semiconductor device having an enlarged contact area between a contact structure and a substrate, the substrate may include a first region on which a conductive structure is arranged and a second region defining the first region. The first region may include a multi-faced polyhedral recess of which at least one of the sidewalls is slanted with respect to a surface of the substrate. An insulation layer may be formed on the substrate to a thickness that is sufficient to cover the conductive structure. The insulation layer has a contact hole that may be communicated with the recess. The active region of the substrate is exposed through the contact hole. A conductive pattern is positioned in the recess and the contact hole. Accordingly, the contact resistance at the active region of the substrate may be kept to a relatively low value even though the gap distances and line width of pattern lines are reduced. |
US08723295B2 |
Semiconductor device, manufacturing method thereof, electronic device and vehicle
The present invention makes it possible to inhibit an SOA (Safe Operating Area) in a vertical-type bipolar transistor from narrowing. A p-type base layer 150 includes a first peak, a second peak, and a third peak in an impurity profile in the thickness direction. The first peak is located on the topmost surface side of a semiconductor substrate 100. The second peak is located closer to the bottom face side of the semiconductor substrate 100 than the first peak and higher than the first peak. The third peak is located between the first peak and the second peak. |
US08723294B2 |
Resistance element and inverting buffer circuit
It is possible to suppress a change in a resistance value caused by a potential of a semiconductor substrate 10 near a resistance element layer 13, a power line passing on or above the resistance element layer, or a signal line, without generating useless current or a distortion in a signal. A first conductive layer 15 biased by the potential of a first electrode 11 and a second conductive layer 16 biased by the potential of a second electrode 12 cover below the resistance element layer equally. A change in the resistance value caused by a potential difference between the resistance element layer and a neighboring semiconductor substrate 14 is cancelled by the first conductive layer and the second conductive layer covering at least one of above and below the resistance element layer with both ends biased, so the change in the resistance value is suppressed. |
US08723289B2 |
Interconnection wiring structure of a semiconductor memory device
A method for manufacturing an interconnection wiring structure of a semiconductor device includes forming an isolation region, which arranges active regions in a diagonal direction, in a semiconductor substrate; forming first damascene trenches, which open upper portions of a bit line contacts, by selectively etching a second interlayer insulation layer; forming bit lines which fill the first damascene trenches; forming second damascene trenches, which expose portions of the active region, by selectively etching the portion of a second interlayer insulation layer between the bit lines and the portion of the first interlayer insulation layer thereunder; attaching trench spacer on side walls of the second damascene trench; and forming storage node contact lines which fill the second damascene trenches. |
US08723287B2 |
Thermal airlflow sensor
An object of the present invention is to provide a thermal airflow sensor that prevents moisture absorption by a silicon oxide film formed closest to a surface (formed to be located on an uppermost portion), and that reduces a measuring error. In order to attain the foregoing object, the thermal airflow sensor according to the present invention applies an ion implantation to a silicon oxide film 4, formed closest to a surface (formed to be located on an uppermost portion), by using an atom or molecule selected from at least any one of silicon, oxygen, and an inert element such as argon or nitrogen, in order to increase a concentration of an atom contained in the silicon oxide film 4 more than that before the ion implantation. |
US08723283B2 |
Optical module
An optical module includes a stem, an optical element, data signal lead pins, a printed circuit board, and a post portion. The optical element is mounted on one surface of the stem. The data signal lead pins are connected to the optical element, and protrudes through the other surface of the stem. The printed circuit board has one surface on which data signal transmission lines for contact with the data signal lead pins are formed and the other surface on a part of which a stiffener is formed to protrude. The post portion protrudes from the other surface of the stem, supports the printed circuit board while in close contact with the stiffener such that the data signal lead pins can contact the data signal transmission lines while being disposed linearly above the data signal transmission lines, and includes a coupling portion to be coupled with the stiffener. |
US08723281B2 |
Access transistor with a buried gate
A magnetic memory cell is formed including a magneto tunnel junction (MTJ) and an access transistor, which is used to access the MTJ in operation. The access transistor, which is formed on a silicon substrate, includes a gate, drain and source with the gate position substantially perpendicular to the plane of the silicon substrate thereby burying the gate and allowing more surface area on the silicon substrate for formation of additional memory cells. |
US08723279B2 |
MEMS sensor, and MEMS sensor manufacturing method
MEMS sensor including substrate, lower thin film confronting one face of the substrate with a space therebetween and having lower through holes extending in the thickness direction thereof, and upper thin film arranged on the opposite side of the substrate confronting the lower thin film with a space therebetween and having upper through holes extending in the thickness direction. A MEMS sensor manufacturing method includes forming a first sacrificing layer on one face of a substrate, forming a lower thin film on the first sacrificing layer with lower through holes individually extending in the thickness direction, forming a second sacrificing layer on the lower thin film, forming an upper thin film on the second sacrificing layer with upper through holes individually extending in the thickness direction, removing the second sacrificing layer through the upper through holes by etching, and removing the first sacrificing layer through the upper and lower through holes by etching. |
US08723278B2 |
Sensor element array and method of fabricating the same
A sensor element array and method of fabricating the same are provided. The sensor element array is disposed on a substrate and includes a first patterned conductive layer, a channel layer, a first insulation layer, a second patterned conductive layer, a second insulation layer, and a third patterned conductive layer. The first patterned conductive layer includes a sensing line, a first power line, a source/drain pattern and a branch pattern. The channel layer includes a first channel and a second channel. Margins of the first insulation layer and the second patterned conductive layer are substantially overlapped. The second patterned conductive layer includes a selecting line, a gate pattern, and a gate connecting pattern. The second insulation layer has a first connecting opening for exposing the gate connecting pattern. The third patterned conductive layer includes a sensing electrode electrically connected to the gate connecting pattern. |
US08723275B2 |
Semiconductor device with metal silicides having different phases
A fully silicided gate with a selectable work function includes a gate dielectric over the substrate, a first metal silicide layer over the gate dielectric, and a second metal silicide layer wherein the first metal silicide has a different phase then the second metal silicide layer. The metal silicide layers comprises at least one alloy element. The concentration of the alloy element on the interface between the gate dielectric and the metal silicide layers influence the work function of the gate. |
US08723271B2 |
Voids in STI regions for forming bulk FinFETs
An integrated circuit structure includes a substrate; two insulation regions over the substrate, with one of the two insulation regions including a void therein; and a first semiconductor strip between and adjoining the two insulation regions. The first semiconductor strip includes a top portion forming a fin over top surfaces of the two insulation regions. |
US08723270B2 |
Semiconductor memory device and fabrication process thereof
A SRAM includes a first CMOS inverter of first and second MOS transistors connected in series, a second CMOS inverter of third and fourth MOS transistors connected in series and forming a flip-flop circuit together with the first CMOS inverter, and a polysilicon resistance element formed on a device isolation region, each of the first and third MOS transistors is formed in a device region of a first conductivity type and includes a second conductivity type drain region at an outer side of a sidewall insulation film of the gate electrode with a larger depth than a drain extension region thereof, wherein a source region is formed deeper than a drain extension region, the polysilicon gate electrode has a film thickness identical to a film thickness of the polysilicon resistance element, the source region and the polysilicon resistance element are doped with the same dopant element. |
US08723268B2 |
N-channel and P-channel end-to-end finFET cell architecture with relaxed gate pitch
A finFET block architecture uses end-to-end finFET blocks in which the fin lengths are at least twice the contact pitch, whereby there is enough space for interlayer connectors to be placed on the proximal end and the distal end of a given semiconductor fin, and on the gate element on the given semiconductor fin. A first set of semiconductor fins having a first conductivity type and a second set of semiconductor fins having a second conductivity type can be aligned end-to-end. Interlayer connectors can be aligned over corresponding semiconductor fins which connect to gate elements. |
US08723267B2 |
Integrated circuit made out of SOI with transistors having distinct threshold voltages
The invention relates to an integrated circuit including an active semiconducting layer separated from a semiconducting substrate layer by an embedded insulating material surface, including: first and second transistors (205, 213) of a single type; first and second floorplans arranged vertically perpendicular to the first and second transistors; wherein the first transistor has a doping of the floorplan thereof, opposite that of the source thereof, and a first threshold voltage; the second transistor has a doping of the floorplan thereof, identical to that of the source thereof, and a second threshold voltage; the first threshold voltage is dependent on the potential difference applied between the source and the floorplan of the first transistor; and the second threshold voltage is dependent on the potential difference applied between the source and the floorplan of the second transistor. |
US08723263B2 |
Electrostatic discharge protection device
An electrostatic discharge (ESD) includes a semiconductor substrate having the first conductive type, a well having the first conductive type, a buried layer having the second conductive type and a well having the second conductive type. The buried layer having a second conductive type is disposed in the semiconductor substrate under the well having the first conductive type. The well having the second conductive type disposed to divide the well having the first conductive type into a first well and a second well. The well having the second conductive type contacts the buried layer, and the well having the second conductive type and the buried layer are jointly used to isolate the first well from the second well. |
US08723262B2 |
SOI FinFET with recessed merged fins and liner for enhanced stress coupling
FinFETS and methods for making FinFETs with a recessed stress liner. A method includes providing an SOI substrate with fins, forming a gate over the fins, forming an off-set spacer on the gate, epitaxially growing a film to merge the fins, depositing a dummy spacer around the gate, and recessing the merged epi film. Silicide is then formed on the recessed merged epi film followed by deposition of a stress liner film over the FinFET. By using a recessed merged epi process, a MOSFET with a vertical silicide (i.e. perpendicular to the substrate) can be formed. The perpendicular silicide improves spreading resistance. |
US08723260B1 |
Semiconductor radio frequency switch with body contact
The present disclosure relates to a radio frequency (RF) switch that includes multiple body-contacted field effect transistor (FET) elements coupled in series. The FET elements may be formed using a thin-film semiconductor device layer, which is part of a thin-film semiconductor die. Conduction paths between the FET elements through the thin-film semiconductor device layer and through a substrate of the thin-film semiconductor die may be substantially eliminated by using insulating materials. Elimination of the conduction paths allows an RF signal across the RF switch to be divided across the series coupled FET elements, such that each FET element is subjected to only a portion of the RF signal. Further, each FET element is body-contacted and may receive reverse body biasing when the RF switch is in an OFF state, thereby reducing an OFF state drain-to-source capacitance of each FET element. |
US08723257B2 |
ESD protection device having reduced equivalent capacitance
An ESD protection device includes a substrate of a first conductivity type, a well region of a second conductivity type, a first doped region of the second conductivity type, a second doped region of the first conductivity type, a third doped region of the second conductivity type, a fourth doped region of the first conductivity type. The well region is configured in the substrate. The first doped region is configured in the well region. The second doped region is configured in the well region and surrounding the first doped region. The third doped region is configured in the well region and surrounding the first doped region and the second doped region. The fourth doped region is configured in the well region and under the first doped region and the second doped region. The fourth doped region is coupled with the first doped region and with the second doped region, respectively. |
US08723256B1 |
Semiconductor device and fabricating method thereof
A semiconductor device is provided. The device includes a semiconductor substrate and a gate structure thereon. A well region is formed in the semiconductor substrate. A drain region and a source region are respectively formed in the semiconductor substrate inside and outside of the well region. At least one set of the first and second heavily doped regions is formed in the well region between the drain region and the source region, wherein the first and second heavily doped regions are stacked vertically from bottom to top and have a doping concentration which is larger than that of the well region. The semiconductor substrate and the first heavily doped region have a first conductivity type and the well region and the second heavily doped region have a second conductivity type. A method for fabricating a semiconductor device is also disclosed. |
US08723253B2 |
Semiconductor device and method for manufacturing same
According to one embodiment, the semiconductor device includes a first semiconductor layer. The semiconductor device includes a plurality of base regions, the base regions are provided on a surface of the first semiconductor layer. The semiconductor device includes a source region selectively provided on each of surfaces of the base regions. The semiconductor device includes a gate electrode provided via a gate insulating film in each of a pair of trenches, each of the trenches penetrate the base regions from a surface of the source region to the first semiconductor layer. The semiconductor device includes a field plate electrode provided via a field plate insulating film in each of the pair of trenches under the gate electrode. A thickness of a part of the field plate insulating film is greater than a thickness of the gate insulating film. |
US08723252B2 |
Vertically-oriented semiconductor selection device providing high drive current in cross-point array memory
A vertical semiconductor material mesa upstanding from a semiconductor base that forms a conductive channel between first and second doped regions. The first doped region is electrically coupled to one or more first silicide layers on the surface of the base. The second doped region is electrically coupled to one of a plurality of second silicide layers on the upper surface of the mesa. A gate conductor is provided on one or more sidewalls of the mesa. |
US08723251B2 |
Semiconductor device and method for forming the same
A semiconductor device and a method for forming the same are disclosed. The semiconductor device includes vertical pillars formed by etching a semiconductor substrate and junction regions which are located among the neighboring vertical pillars and spaced apart from one another in a zigzag pattern. As a result, the semiconductor device easily guarantees an electrical passage between the semiconductor substrate and the vertical pillars, such that it substantially prevents the floating phenomenon from being generated, resulting in the prevention of deterioration of the semiconductor device. |
US08723250B2 |
Integrated circuit devices including complex dielectric layers and related fabrication methods
An electronic device includes a lower layer, a complex dielectric layer on the lower layer, and an upper layer on the complex dielectric layer. The complex dielectric layer includes an amorphous metal silicate layer and a crystalline metal-based insulating layer thereon. Related fabrication methods are also discussed. |
US08723248B2 |
Nonvolatile semiconductor storage device
In one embodiment, there is provided a nonvolatile semiconductor storage device. The device includes: a plurality of nonvolatile memory cells. Each of the nonvolatile memory cells includes: a first semiconductor layer including a first source region, a first drain region, and a first channel region; a block insulating film formed on the first channel region; a charge storage layer formed on the block insulating film; a tunnel insulating film formed on the charge storage layer; a second semiconductor layer formed on the tunnel insulating film and including a second source region, a second drain region, and a second channel region. The second channel region is formed on the tunnel insulating film such that the tunnel insulating film is located between the second source region and the second drain region. A dopant impurity concentration of the first channel region is higher than that of the second channel region. |
US08723242B2 |
Non-volatile semiconductor memory device and method of manufacturing the same
A non-volatile semiconductor memory device and a method of manufacturing the same of the embodiments are provided. The non-volatile semiconductor memory device includes: drain contact plugs formed in memory cell regions and having bottom ends joined to drain diffusion layers of the respective memory cells; a local interconnect provided to extend in a WL direction across the memory cell regions and a shunt region, and having a bottom end joined commonly to plural source diffusion layers; drain via plugs formed in the memory cell regions and having bottom ends joined to the top ends of the respective drain contact plugs; and a power supply via for source formed in the shunt region to extend in a BL direction, and having a bottom end joined to the top end of the local interconnect. |
US08723240B2 |
Semiconductor device, manufacturing method for the same, and electronic device
A manufacturing method for a semiconductor device, the method including forming a thin film transistor by forming a polysilicon thin film on an insulating substrate, forming a gate electrode via a gate insulating film, and forming source/drain regions and a channel region by ion implantation in the polysilicon thin film by using the gate electrode as a mask, forming an interconnection layer on an interlayer dielectric film covering this thin film transistor and forming a first contact to be connected to the thin film transistor through the interlayer dielectric film, forming a silicon hydronitride film on the interlayer dielectric film so as to cover the interconnection layer, forming a lower electrode on this silicon hydronitride film and forming a second contact to be connected to the interconnection layer through the silicon hydronitride film, and forming a ferroelectric layer on the lower electrode. |
US08723231B1 |
Semiconductor die micro electro-mechanical switch management system and method
A die micro electro-mechanical switch management system and method facilitate power conservation by selectively preventing electrical current from flowing in designated components. A present invention semiconductor die comprises a block of transistors for performing switching operations, a bus (e.g., a power bus, a signal bus, etc.) for conveying electrical current and a micro electro-mechanical switch that couples and decouples the block of transistors to and from the bus. The micro electro-mechanical switch is opened and closed depending upon operations (e.g., switching operations) being performed by the block of transistors. Electrical current is prevented from flowing to the block of transistors when the micro electro-mechanical switch is open and the block of transistors is electrically isolated. The micro electro-mechanical switch can interrupt electrical current flow in a plurality of the bus lines and/or can be included in a relay array. |
US08723229B2 |
Semiconductor device and method of manufacturing the device
In a manufacturing method of a semiconductor device, first, a first semiconductor layer, a second semiconductor layer, and a p-type third semiconductor layer are sequentially epitaxially grown on a substrate. After that, the third semiconductor layer is selectively removed. Then, a fourth semiconductor layer is epitaxially grown on the second semiconductor layer. Then, a gate electrode is formed on the third semiconductor layer. |
US08723226B2 |
Manufacturable enhancement-mode group III-N HEMT with a reverse polarization cap
An enhancement-mode group III-N high electron mobility transistor (HEMT) with a reverse polarization cap is formed in a method that utilizes a reverse polarization cap structure, such as an InGaN cap structure, to deplete the two-dimensional electron gas (2DEG) and form a normally off device, and a spacer layer that lies below the reverse polarization cap structure and above the barrier layer of the HEMT which allows the reverse polarization cap layer to be etched without etching into the barrier layer. |
US08723223B2 |
Hybrid Fin field-effect transistors
A hybrid Fin Field-Effect Transistor (FinFET) includes a first and a second FinFET. The first FinFET includes a first channel region formed of a first semiconductor fin, and a first source region and a first drain region of a first conductivity type. The second FinFET includes a second channel region formed of a second semiconductor fin, a second source region of a second conductivity type opposite the first conductivity type, and a second drain region of the first conductivity type. The second source region and the second drain region are connected to opposite ends of the second channel region. The first and the second gate electrodes are interconnected. The first and the second source regions are electrically interconnected. The first and the second drain regions are electrically interconnected. |
US08723220B2 |
Semiconductor device
A reverse conducting semiconductor device having an IGBT element region and a diode element region in one semiconductor substrate is provided. An electric current detection region is arranged adjacent to the IGBT element region, and a collector region of the IGBT element region is extended to connect with a collector region of the electric current detection region. Instability in the IGBT detection current caused by a boundary portion between the IGBT and the diode can be suppressed. In the same way, an electric current detection region is arranged adjacent to the diode element region, and a cathode region of the diode element region is extended to connect with a cathode region of the electric current detection region. Instability in the diode detection current caused by the boundary portion between the IGBT and the diode can be suppressed. |
US08723219B2 |
Chamfered freestanding nitride semiconductor wafer and method of chamfering nitride semiconductor wafer
Technology of making freestanding gallium nitride (GaN) wafers has been matured at length. Gallium nitride is rigid but fragile. Chamfering of a periphery of a GaN wafer is difficult. At present edges are chamfered by a rotary whetstone of gross granules with weak pressure. Minimum roughness of the chamfered edges is still about Ra 10 μm to Ra 6 μm. The large edge roughness causes scratches, cracks, splits or breaks in transferring process or wafer process. A wafer of the present invention is bevelled by fixing the wafer to a chuck of a rotor, bringing an edge of the wafer into contact with an elastic whetting material having a soft matrix and granules implanted on the soft matrix, rotating the wafer and feeding the whetting material. Favorably, several times of chamfering edges by changing the whetting materials of smaller granules are given to the wafer. The chamfering can realize small roughness of Ra10 nm and Ra5 μm at edges of wafers. |
US08723217B2 |
White light emitting diode package
Disclosed is a light emitting diode package having a simplified configuration and high color reproducibility. The light emitting diode package includes a package body, first and second light emitting diode chips received in the package body, a lead frame electrically connected to the first and second light emitting diode chips, the lead frame serving to adjust color of light according to the ratio of current of the first and second light emitting diode chips, and a light conversion layer configured to cover the first and second light emitting diode chips, the light conversion layer serving to convert light emitted from the first and second light emitting diode chips into a particular wavelength of light so as to emit a desired wavelength of light. |
US08723215B2 |
LED module
A LED module includes a substrate, a LED chip supported on the substrate, a metal wiring installed on the substrate, the metal wiring including a mounting portion on which the LED chip is mounted, an encapsulating resin configured to cover the LED chip and the metal wiring, and a clad member configured to cover the metal wiring to expose the mounting portion, the encapsulating resin arranged to cover the clad member. |
US08723214B2 |
Submount and manufacturing method thereof
A submount and a manufacturing method thereof are provided. The submount, on which at least a semiconductor die is disposed, is mounted on a circuit board. The submount includes a substrate made of a conductive material or a semiconducting material, a plurality of conductive film patterns, and an insulating film pattern. A surface of the substrate includes a die-bonding area and a plurality of conductive areas. The conductive film patterns are individually distributed in the respective conductive areas. The insulating film pattern is disposed between the conductive film pattern and the insulating film pattern, but is not disposed in the die-bonding area. Furthermore, the semiconductor die is disposed in the die-bonding area and is electrically connected with the conductive film patterns. Because the insulating film pattern is not being disposed in the die-bonding area of the submount, the submount structure has improved heat transfer efficiency. |
US08723213B2 |
Light emitting device and light emitting device package
Provided is a light emitting device. In one embodiment, a light emitting device including: a support member; a light emitting structure on the support member, the light emitting structure comprising a first conductive type semiconductor layer, a second conductive type semiconductor layer, and an active layer between the first conductive type semiconductor layer and the second conductive type semiconductor layer; a protective member at a peripheral region of an upper surface of the support member; an electrode including an upper portion being on the first conductive type semiconductor layer, a side portion extended from the upper portion and being on a side surface of the light emitting structure, and an extended portion extended from the side portion and being on the protective member; and an insulation layer between the side surface of the light emitting structure and the electrode. |
US08723209B2 |
Out coupling layer containing particle polymer composite
Light emitting devices comprising an optical layer comprising metal oxide particles having a polymer covalently bonded thereto and a light emitting layer, which is in optical communication with the optical layer are provided. Methods of fabricating a light emitting devices comprising: depositing an optical layer comprising metal oxide particles having a polymer covalently bonded thereto; and depositing a light emitting layer, which is in optical communication with the optical layer are also provided. |
US08723207B2 |
Radiation-emitting optical component
A radiation-emitting semiconductor component, having a layer structure which includes an active layer which, in operation, emits radiation with a spectral distribution, and electrical contacts for applying a current to the layer structure, includes a coating layer which at least partially surrounds the active layer and holds back a short-wave component of the emitted radiation. |
US08723206B2 |
Semiconductor light emitting device with contact hole passing through active layer
A semiconductor light emitting device has a semiconductor laminate including first and second conductivity type semiconductor layers respectively providing first and second main surfaces and an active layer. The semiconductor laminate is divided into first and second regions. At least one contact hole is formed to pass through the active layer from the second main surface of the first region. A first electrode is formed on the second main surface to be connected to the first conductivity type semiconductor layer of the first region and the second conductivity type semiconductor layer of the second region. A second electrode is formed on the second main surface of the first region to be connected to the second conductivity type semiconductor layer of the first region and the first conductivity type semiconductor layer of the second region. |
US08723205B2 |
Phosphor incorporated in a thermal conductivity and phase transition heat transfer mechanism
A thermal conductivity and phase transition heat transfer mechanism has an opto-luminescent phosphor contained within the vapor chamber of the mechanism. The housing includes a section that is thermally conductive and a member that is at least partially optically transmissive, to allow emission of light produced by excitation of the phosphor. A working fluid also is contained within the chamber. The pressure within the chamber configures the working fluid to absorb heat during operation of the lighting device, to vaporize at a relatively hot location at or near at least a portion of the opto-luminescent phosphor as the working fluid absorbs heat, to transfer heat to and condense at a relatively cold location, and to return as a liquid to the relatively hot location. Also, the working fluid is in direct contact with or contains at least a portion of the opto-luminescent phosphor. |
US08723200B2 |
Lead frame, light emitting diode having the lead frame, and backlight unit having the light emitting diode
An LED includes a light-emitting chip, a metal member, and a housing. The light-emitting chip generates light. The light-emitting chip is arranged on the metal member. The housing is combined with the metal member to fix the metal member. The housing has an opening portion exposing at least a portion of the light-emitting chip and the metal member. The metal member includes a base metal layer, a light-reflecting layer arranged on the base metal layer, and a protection layer arranged on the light-reflecting layer and including a metal. |
US08723199B2 |
Radiation emitting body and method for producing a radiation-emitting body
A radiation-emitting body comprising a layer sequence, having an active layer (10) for generating electromagnetic radiation, having a reflection layer (50), which reflects the generated radiation, and having at least one intermediate layer (40) arranged between the active layer (10) and the reflection layer (50). In this case, the active layer (10) has a roughening on an interface (15) directed toward the reflection layer (50), and the reflection layer (50) is substantially planar at an interface (45) directed toward the active layer (10). Also disclosed is a method for producing a radiation-emitting body, which involves forming a layer sequence on a substrate having an active layer (10) for generating electromagnetic radiation. In this case, the method comprises roughening an interface (15) on the active layer (10), and forming at least one intermediate layer (40) and a reflection layer (50). |
US08723195B2 |
Light emitting device with plurality of LED chips and/or electrode wiring pattern
A light emitting device includes a substrate having a rectangular outer shape in a top view, a plurality of LED chips, a resin frame formed on the primary surface of the substrate and provided annularly so as to surround a mounting area in which the LED chips are provided, an anode-side electrode land and a cathode-side electrode land which are electrodes to be connected to an external voltage supply of said light emitting device. An electrode wiring pattern may be formed on the primary surface of the substrate including (i) an anode line extending from the anode-side electrode land to a portion under the resin frame and (ii) a cathode line extending from the cathode-side electrode land to the other portion under the resin frame. |
US08723188B2 |
Light emitting diode and method for preparing the same
A light emitting diode includes a substrate comprising a plurality of first grooves and a plurality of first convex parts formed on a surface of the substrate, with the first groove formed between two neighboring first convex parts; a semiconductor structure formed on the substrate comprising a plurality of second convex parts corresponding to the plurality of first grooves and a plurality of second grooves corresponding to the plurality of first convex parts; a transparent conductive layer formed on the semiconductor structure and configured to transmit a current to the plurality of second convex parts; a first electrode electrically connected with the semiconductor structure; and a second electrode electrically connected with the transparent conductive layer. A method for preparing the light emitting diode is also provided. |
US08723187B2 |
Integrated diamond transduction pixelized imager device and manufacturing process
Imaging device including several pixels, each pixel including at least: a portion of a diamond layer placed between a first and second electrode, and able to achieve transduction of photons and/or high energy particles radiation into an electrical signal. an electronic circuit for amplification and/or reading of the electrical signal, electrically connected to at least the first electrode and made in a portion of a semiconductor material layer having a thickness lower than or equal to around 1 μm and forming the surface layer of an SOD type substrate, also including the diamond layer and a dielectric layer placed between the diamond layer and the electronic circuit. |
US08723183B2 |
Image display system having pixels with common electrodes
A pixel driving circuit array is disclosed, comprising a first capacitor and a second capacitor. The first capacitor comprises a first electrode, an insulator layer and a common electrode. The second capacitor comprises a second electrode, the insulator layer and the common electrode. The first capacitor and the second capacitor share the same common electrode. The first electrode and the second electrode are on the same plane. |
US08723174B2 |
Thin film transistor, contact structure, substrate, display device, and methods for manufacturing the same
A TFT 17 provided on a substrate 3 is provided. The TFT 17 includes a gate electrode 31, a gate insulating film 32, a semiconductor 33, a source electrode 34, a drain electrode 35, and a protection film 36. The semiconductor 33 includes a metal oxide semiconductor. The semiconductor 33 has a source portion 33a which is in contact with the source electrode 34, a drain portion 33b which is in contact with the drain electrode 35, and a channel portion 33c which is exposed through the source electrode 34 and the drain electrode 35. A conductive layer 37 having a relatively small electrical resistance is formed in each of the source portion 33a and the drain portion 33b. The conductive layer 37 is removed from the channel portion 33c. |
US08723171B2 |
Organic electroluminescence device
An organic electroluminescence device including opposite anode and cathode, and a hole-transporting region, an emitting layer and an electron-transporting region in sequential order from the anode between the anode and the cathode, wherein the emitting layer includes a red emitting portion, a green emitting portion, and a blue emitting portion; the blue emitting portion includes a host BH and a fluorescent dopant FBD; the triplet energy ETfbd of the fluorescent dopant FBD is larger than the triplet energy ETbh of the host BH; the green emitting portion includes a host GH and a phosphorescent dopant PGD; the electron-transporting region includes a common electron-transporting layer adjacent to the red emitting portion, the green emitting portion and the blue emitting portion; the common electron-transporting layer includes a material having a triplet energy ETel larger than ETbh; and the difference between the affinity of the host GH and the affinity of the material constituting the common electron-transporting layer is 0.4 eV or less. |
US08723169B2 |
Enhancing performing characteristics of organic semiconducting films by improved solution processing
Improved processing methods for enhanced properties of conjugated polymer films are disclosed, as well as the enhanced conjugated polymer films produced thereby. Addition of low molecular weight alkyl-containing molecules to solutions used to form conjugated polymer films leads to improved photoconductivity and improvements in other electronic properties. The enhanced conjugated polymer films can be used in a variety of electronic devices, such as solar cells and photodiodes. |
US08723168B2 |
Display, method of manufacturing the same, and electronic unit
A display includes: a first light-emitting device disposed in a first region on a substrate and including a transfer organic layer; a second light-emitting device disposed in a second region adjacent to the first region on the substrate and not including a transfer organic layer; and a level difference provided between the first region and the second region, and being large enough to inhibit transfer of the transfer organic layer to the second region when the transfer organic layer is formed in the first region. |
US08723165B2 |
Vertical electro-optical component and method of fabricating the same
A vertical electro-optical component and a method for forming the same are provided. The vertical electro-optical component includes a substrate, a first electrode layer formed on the substrate, a patterned insulating layer formed on the first electrode layer, a metal layer formed on the patterned insulating layer, a semiconductor layer formed on the first electrode layer, and a second electrode layer formed on the semiconductor layer, wherein the semiconductor layer encapsulates the patterned insulating layer and the metal layer. The vertical electro-optical component thus has a low operational voltage of a vertical transistor and a high reaction speed of a photo diode, and may be used to form light-emitting transistors. |
US08723163B2 |
Organic photoelectric converter
Disclosed is an organic photoelectric conversion device including a pair of electrodes, at least one of which is transparent or semi-transparent, and an organic layer arranged between the electrodes and containing a conjugated polymer compound and a sulfur-containing heterocyclic compound, wherein the sulfur-containing heterocyclic compound has a condensed polycyclic structure or a bithiophene structure. Examples of the sulfur-containing heterocyclic compound include a compound represented by formula (1): (wherein, a plurality of R1's may be the same or different and each represents a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, an alkylthio group, an aryl group, an aryloxy group, an arylthio group, an arylalkyl group, an arylalkoxy group or an arylalkylthio group, and a hydrogen atom or atoms contained in these groups may be substituted by a fluorine atom or atoms; and m represents an integer of 0 to 10) or the like. |
US08723156B2 |
Resistive switching memory elements having improved switching characteristics
Resistive-switching memory elements having improved switching characteristics are described, including a memory element having a first electrode and a second electrode, a switching layer between the first electrode and the second electrode comprising hafnium oxide and having a first thickness, and a coupling layer between the switching layer and the second electrode, the coupling layer comprising a material including metal titanium and having a second thickness that is less than 25 percent of the first thickness. |
US08723149B2 |
Systems and methods for advanced monitoring and control using an LED driver in an optical processor
Systems and methods for advanced monitoring and control using an LED driver in an optical processor are described. In an embodiment, a monitoring and control circuit may include a light-emitting diode (LED) driver including a control input, an output, and a node, wherein the output is coupled to an LED. The circuit may also include a multiplexer coupled to the node of the LED driver, an analog-to-digital converter coupled to the multiplexer, and a controller coupled to the analog-to-digital converter and to the control input of the LED driver, wherein the LED driver is coupled to drive the output with a first voltage supply that is independent from a second voltage supply that is coupled to drive the controller. |
US08723145B2 |
Plasmonic polarizer with a ring shaped waveguide
A radiation-emitting device (e.g., a laser) includes an active region configured to generate a radiation emission linearly polarized along a first polarization direction and a device facet covered by an insulating layer and a metal layer on the insulating layer. The metal layer defines an aperture through which the radiation emission from the active region can be transmitted and coupled into surface plasmons on the outer side of the metal layer. The long axis of the aperture is non-orthogonal to the first polarization direction, and a sequential series of features are defined in or on the device facet or in the metal layer and spaced apart from the aperture, wherein the series of features are configured to manipulate the surface plasmons and to scatter surface plasmons into the far field with a second polarization direction distinct from the first polarization direction. |
US08723140B2 |
Particle analyzer with spatial modulation and long lifetime bioprobes
An analyzer includes a flow cell having a flow channel through which a sample passes. A light source excites at least a first particle type in the sample in one or more excitation region(s), and a detector detects light emitted by the excited particle. A spatial filter defines detection regions, wherein light emitted by the particle is transmitted to the detector, and interspersed shielded regions, wherein such light is at least partially blocked from reaching the detector. The light emitted by the excited particle has a response time τ1, and the sample may also contain a component that is excited by the light source and that has a response time τ2<τ1. The excitation region(s) and the detection regions are arranged to provide a time delay between excitation and detection, the time delay tailored to isolate light emitted by the first particle from light emitted by the component. |
US08723128B2 |
Nuclear medicine imaging apparatus and nuclear medicine imaging method
In the nuclear medicine imaging apparatus according to the one embodiment, the ADC converts the output data of each of the photodetectors to digital data. The counting information collecting unit collects counting results from the digital data, and the counting information storage unit stores the counting result in association with the digital data. The coincidence counting information generating unit generates coincidence counting information. The image reconstructing unit reconstructs a PET image, based on the coincidence counting information. The time correction data stores a correction time for each of the photodetectors. The system controlling unit controls to correct the detection time of the gamma rays in the digital data associated with each piece of the counting information by use of the correction time, and to generate new coincidence counting information. The system controlling unit controls to reconstruct a new nuclear medicine image, based on the new coincidence counting information generated. |
US08723126B2 |
Scintillator material
A device having: a scintillator material having an atom having an atomic number of at least 45, and one or more photomultiplier tubes adjacent to the scintillator material. |
US08723125B1 |
Waveguide end-coupled infrared detector
A Ge waveguide photo-detector fabricated on a silicon-on-insulator substrate is provided. It comprises a Ge waveguide detector end-coupled to a light-signal-carrying silicon waveguide, both disposed on a silicon-on-insulator (SOI) substrate. An electrical field is established along the direction of light propagation inside the Ge waveguide detector by doping the two opposite ends of the Ge detector with P or N type dopants. In result the height and width of the Si waveguide is decoupled from the speed of the Ge detector. |
US08723123B2 |
Light detector with Ge film
A light detector includes a first light sensor and a second light sensor to detect incident light. A Ge film is disposed over the first light sensor to pass infra-red (IR) wavelength light and to block visible wavelength light. The Ge film does not cover the second light sensor. |
US08723122B2 |
Infrared sensor module, touch sensing method thereof, and auto calibration method applied to the same
An infrared sensor module, a touch sensing method thereof, and an auto calibration method applied to the same are disclosed, the touch sensing method includes turning on the infrared sensor module which includes a sensor block with a light receiving region and is arranged to be perpendicular to a surface of a display panel, the light receiving region being divided into m×n blocks (where, each of m and n is a natural number of two or more) arranged in m rows by n columns, each of the blocks having a plurality of light receiving pixels arranged in a row direction, scanning optical signals of each block, selecting the block having maximum output optical signals with respect to the blocks of each column, and summing the optical signals of the light receiving pixels of the block selected from the column. |
US08723116B2 |
Method of determining an applicable threshold for determining the critical dimension of at least one category of patterns imaged by atomic force scanning electron microscopy
A method of determining an applicable threshold for determining the critical dimension of a category of patterns imaged by atomic force scanning electron microscopy is presented. The method includes acquiring, from a plurality of patterns, a pair of images for each pattern; for each pair of images determining a reference critical dimension via an image obtained by a reference instrumentation and determining an empirical threshold applicable to an image obtained by a CD-SEM instrumentation such that the empirical threshold substantially corresponds to the reference critical dimension; determining a threshold applicable to a category of patterns, the threshold being determined from a plurality of empirical thresholds. |
US08723114B2 |
Sequential radial mirror analyser
A sequential radial mirror analyzer (RMA) (100) for facilitating rotationally symmetric detection of charged particles caused by a charged beam incident on a specimen (112) is disclosed. The RMA comprises a 0V equipotential exit grid (116), and a plurality of electrodes (119, 120a, 120b, 120c) electrically configured to generate corresponding electrostatic fields for deflecting at least some of the charged particles of a single energy level to exit through the exit grid (116) to form a second-order focal point on a detector (106). The second-order focal point is associated with the single energy level, and the detector (106) is disposed external to the corresponding electrostatic fields. A related method is also disclosed. |
US08723113B2 |
Radio-frequency-free hybrid electrostatic/magnetostatic cell for transporting, trapping, and dissociating ions in mass spectrometers
Mass spectrometry cells include one or more interleaved magnetostatic and electrostatic lenses. In some examples, the electrostatic lenses are based on electrical potentials applied to magnetostatic lens pole pieces. In other alternatives, the electrostatic lenses can include conductive apertures. Applied voltages can be selected to trap or transport charged particles, and photon sources, gas sources, ion sources, and electron sources can be provided for various dissociation processes. |
US08723112B2 |
Controller and control method for improving signal performance of ion cyclotron resonance mass spectrometer
Provided are a controller and a control method for improving signal performance of an ion cyclotron resonance mass spectrometer. The controller and control method apply electric signals for causing ions injected into an ion trap of the ion cyclotron resonance mass spectrometer to be injected to the center of the trap as close as possible to trap electrodes, and adjust biased ion motion by appropriately adjusting signals of trap electrodes for causing the injected ions to make ion motion, thereby improving the fidelity of ion signals. The control method for improving signal performance of an ion cyclotron resonance mass spectrometer includes an ion position adjustment process and an ion signal detection process. |
US08723106B2 |
Method and apparatus for identification of biological material
Biological material is detected in a sample using a MALDI-MS technique (Matrix Assisted Laser Desorption and Ionization-Mass Spectroscopy). A liquid comprising the sample and a MALDI matrix material is prepared and used to form a continuous stream of the liquid. The stream is separated into successive parts to form drops, which are launched into flight, or the stream is launched into flight and then separated into drops. Drop forming techniques may be used that are known from ink jet printers. Material from the drops is ionized while in flight. Mass spectra from the ionized material of respective drops are measured. Preferably, before the drops are formed the liquid is diluted to a level where the majority of drops at most one micro-organism is present per drop. |
US08723104B2 |
Methods and means for manipulating particles
The present invention is concerned with a system for sorting target particles from a flow of particles. The system has a microscope, a light source, a CCD camera, microfluidic chip device with microfluidic channels, a detection apparatus for detecting the target particles with predefined specific features, a response generating apparatus for generating a signal in response to the detection of the target particles, and an optical tweezing system for controlling movement of optical traps, the optical tweezing system is operably linked to the response signal. |
US08723101B2 |
Integrated movement sensing key with a reflection unit comprising semicircle motifs
The present invention relates to an integrated key using an optical key, in particular, to an integrated key which enables a more subdivided manipulation for the movement to the outside based on a center point, and to perform the operation of rotation and push. An integrated key using an optical sensor of the invention includes a housing which has an accommodation space inside while an upper portion is open; an operation member which has a guide unit which sticks to the housing between an upper end and a lower end of the operation member while a handle is formed in an upper side and a reflection unit is formed at a bottom surface; and an optical sensor which measures one or more of a separation distance with the reflection a rotation of the operation member, and a location coordinate value of the operation member, and outputs a sensing signal according to the measurement. |
US08723100B2 |
Method of detecting impinging position of photons on a geiger-mode avalanche photodiode, related geiger-mode avalanche photodiode and fabrication process
A Geiger-mode avalanche photodiode may include an anode, a cathode, an output pad electrically insulated from the anode and the cathode, a semiconductor layer having resistive anode and cathode regions, and a metal structure in the semiconductor layer and capacitively coupled to a region from the resistive anode and resistive cathode regions and connected to the output pad. The output pad is for detecting spikes correlated to avalanche events. |
US08723097B2 |
Illuminance sensor having light-level-independent consumption current
Provided is an illuminance sensor in which a consumption current is independent of an illuminance level of incident light. Amplifiers (21 to 24) and a subtraction circuit (25) are driven by a constant current source (not shown). The subtraction circuit (25) outputs a differential voltage between output voltages of a photodetector element (15) and a photodetector element (16). Based on the differential voltage, a sample/hold circuit (30) performs sampling or holding of a voltage at one end of a capacitor (13). A switch (28) is ON when an output voltage of the subtraction circuit (25) starts to change, thereby fixing the voltage at the one end of the capacitor (13) to a reference voltage. |
US08723095B2 |
Method and apparatus for ambient light detection including plural image pixels and at least one dark pixel
Electronic devices may be provided with image sensors. Image sensors may be configured to capture images during imaging operations and monitor ambient light levels during non-imaging operations. An image sensor may include image pixels that receive light and dark pixels that are prevented from receiving light. An image sensor may include an ambient light detection circuit. The ambient light detection circuit may include an oscillator, timing and control circuitry, and a counter. The oscillator may be switchably coupled to the image pixels and the dark pixels. The counter may be configured to count up oscillator cycles of the oscillator while the oscillator is coupled to the image pixels and to count down oscillator cycles of the oscillator while the oscillator is coupled to the dark pixels. The counter may provide a count value that depends on a signal from the image pixels and a signal from the dark pixels. |
US08723092B2 |
Light guiding device
The present invention relates to a light guide device for the introduction of sunlight into the interior of a building, having a multitude of movably mounted light deflection surfaces which are adjustable by control means depending on the position of the sun. According to the present invention the light deflecting surfaces of the light guide device are formed by serially arranged deflecting blades which may be swiveled about swivel axes which are approximately parallel to each other, the blades being mounted on a blade holder which is rotatable about a rotational axis which is essentially perpendicular to the direction of the swivel axes. |
US08723086B2 |
Heat lamp
A heating device of a portable nature is disclosed. The heating device of a portable nature includes a heating element, a hinged coupled to the heating element, and an arm coupled to the hinge. |
US08723084B2 |
Household appliance for the production of bread
The household appliance (1) for the production of bread comprises—a cooking chamber (11), —electrical supply means (19) for heating said cooking chamber (11), —a drive means ((12) pivotally activated in said cooking chamber (11) by a geared motor (13), —a container (10) which can be accommodated in said cooking chamber (11) and having at least a containment chamber (2) for the bread and at least a mixing shovel (3) positioned inside said containment chamber (2) and able to be directly or indirectly moved by said drive means (12), said containment chamber (2) being so configured to have a first proportion ratio (R1) between every dimension (A, B, Φ) of its base and its height (H), and a second proportion ratio (R2) between the dimension of its height (H) and the length (L) of said shovel (3), said ratios being able to give to the cooked bread in said containment chamber (2) a mainly low and wide shape with a little crumb. |
US08723083B2 |
Cooking device with arc-shaped electrodes used for boil-over detection
The cooking device includes a top plate on which containers are to be placed, heating devices provided under the top plate, electrodes provided on a lower surface of the top plate, capacitance detection devices for detecting changes in capacitance of the electrodes, and a boil over determination device for determining a liquid boiled over from the containers on the basis of the changes in capacitance detected by the capacitance detection devices in heating operations of the heating devices. The electrodes have a plurality of arc-shaped detection parts provided along periphery of each of the heating devices. |
US08723080B2 |
Arc welding control method and arc welding apparatus
An arc welding control method for carrying out welding by generating an arc between a wire and a base material. The wire is fed at wire feed speed (Wf) of periodically repeating forward feeding and reverse feeding with predetermined frequency and amplitude from time point (100) at which start of the welding is instructed, or from a certain time point (101) after the start of the welding is instructed, and then the wire feed speed is changed to a constant speed. Since the wire feed speed is controlled by periodically repeating forward feeding and reverse feeding at the arc start, short-circuit can be opened regardless of the electromagnetic pinch force, and spatters, which are generated at the early stage of the arc start because a molten pool is not preset, can be reduced. |
US08723079B2 |
Laser soldering using thermal characteristics
In this soldering method, a laser is directed onto an end face of the stack in such a manner that the laser heats the stack. At least one parameter of the laser is adjusted to a value that is the image by a mathematical model of at least one thermal characteristic of the stack. The parameter of the laser is a parameter selected from an irradiation duration, a surface area of the end face of the stack that is irradiated by the laser, and an irradiating power of the laser. |
US08723073B2 |
Illumination apparatus and method for controlling energy of a laser source
The disclosure relates to an illuminating apparatus for illuminating a sample on a work stage, optionally with a relatively narrow illuminating line of relatively controlled energy, as well as methods for controlling energy of a laser source when illuminating a sample on a work stage with a relatively narrow illuminating line. |
US08723072B2 |
Plasma cutter, and plasma cutter power supply system
In a main circuit 11 of the plasma cutter power supply device 6, a plurality of DC power units 14-1, . . . 14-n of low capacity are connected in parallel on their DC output sides, and are connected to a plasma torch 20. Each power unit 14-1, . . . 14-n can operate asynchronously and independently from each other. The power supply control device 6 controls the number of power units to be operated, and the intensity of output electrical current at which each of them is to be operated, according to the cutting conditions (the nature of the material to be cut, its thickness, and the cutting speed) and according to the number of power units which can be operated. If some of the power units are faulty, the power supply control device 6 controls the cutting conditions which can be accepted, according to the number of normal power units. |
US08723071B2 |
Atmospheric shield with a continuous channel seal for isolating welding components
An atmospheric shield for isolating a component from an external atmosphere is provided. The atmospheric shield includes an envelope and a base carrying a continuous channel. The base and the envelope are arranged to define an enclosure within which the component to be isolated is located, and such that a portion of the envelope extends within the continuous channel. A seal is provided within the continuous channel to seal between the envelope and the base. |
US08723066B2 |
Dome switch device
A dome switch device enables electric contact by pressing of a central region or even any other region of a dome sheet formed to extend in a longitudinal direction with the same result regarding the amount of electrical contact. The dome switch device preferably includes a dome sheet extending along a longitudinal direction and having conductivity and a contact module provided on a substrate such that a plurality of both-pole (two-pole) contact portions are arranged alternately along the longitudinal direction of the dome sheet, in which the contact module, when being pressed regardless of where along the dome sheet is pressed, whether being pressed on a central region thereof or any other region other than the central region, electrically contacts the dome sheet with a high quality electrical contact. |
US08723063B2 |
Button assembly for displaying an illuminated symbol
A button assembly for displaying an illuminated symbol with a locking ring having an outer surface. A solid light guide is positioned within and spaced apart from the locking ring. The light guide has a top surface for displaying an illuminated symbol and a bottom surface with a light receiving member having a refracting surface with a first lens member for receiving and directing light to the top surface of the light guide. A resilient sealing member is mounted on the locking ring and interconnects the locking ring and the light guide. The sealing member has an unsupported portion that facilitates movement of the light guide relative to the locking ring. |
US08723057B2 |
Systems and methods for protecting a flight recorder
Systems and methods for protecting a flight recorder are provided. In certain embodiments, a crash survivable memory unit, comprises a memory device that records flight data; a flexible insulation layer that inhibits thermal energy from conducting from an external side of the flexible insulation layer to an internal side of the flexible insulation layer, wherein the internal side faces the memory device; a microlattice layer abutting the internal side and enclosing the memory device, the microlattice layer configured to distribute thermal energy that passes through the flexible insulation layer substantially throughout the microlattice layer; and a heat absorbing material that impregnates the microlattice layer, the heat absorbing material configured to absorb the thermal energy in the microlattice layer; and an impact resistant layer encircling the flexible insulation layer, wherein the impact resistant layer absorbs shocks that result from other objects contacting the impact resistant layer. |
US08723055B2 |
Electric plug system
An electric plug system includes a stabilizing base, a vertical support element extending from the base, a horizontal electrical socket block having a plurality of female electrical sockets that is coupled to the top of the vertical support element, and an electrical wire extending from the horizontal electrical socket block, down the vertical element, and along or through the base and there-beyond and terminating in a male electrical plug adapted to plug into a standard wall or floor electrical outlet. The vertical support element can be a telescoping tube with a height control knob. |
US08723051B2 |
Wiring substrate and method for manufacturing wiring substrate
A wiring substrate includes a substrate body formed of an inorganic material and including a first surface and a second surface, a first trench formed in a first surface side of the substrate body, a second trench formed in a second surface side of the substrate body, a penetration hole penetrating through the substrate body, a first plane layer filling the first trench, a second plane layer filling the second trench, and a penetration wiring filling the penetration hole. The first plane layer is a reference potential layer. The second plane layer is a power supply layer. |
US08723047B2 |
Printed circuit board, design method thereof and mainboard of terminal product
A printed circuit board and a design method thereof are disclosed. The design method includes: wiring signal lines on an area basis at inner layers adjacent to outer surface layers; arranging the outer surface layers with no wiring or few wirings and interconnecting the outer surface layers by way of through vias, so that the outer surface layers function as a primary ground; and setting parameters of a line width and a layer height to control a target impedance value. The printed circuit board includes outer surface layers and two inner layers therebetween. The inner layers adjacent to the outer surface layers are used for arranging signal lines on an area basis; and the outer surface layers are arranged with no wiring or few wirings and are interconnected as a primary ground through vias. The invention also discloses a mainboard of a terminal product using the printed circuit board. |
US08723046B2 |
Narrow frame touch input sheet with good anticorrosion property and manufacturing method thereof
A method of manufacturing a narrow frame touch input sheet having very good anticorrosion properties and suitable for a narrow frame capacitance type touch sensor having a double-layer transparent conductive film pattern. The method uses an electrical conductivity sheet obtained by sequentially forming transparent and light blocking conductive films, and first resist layers, on both sides of a transparent base sheet, exposing and developing the resist layers on both sides simultaneously, etching the transparent and light blocking films simultaneously, removing the resist layers, laminating second resist layers with anticorrosion agent on the revealed light blocking films, etching the light blocking films in center windows and terminal portions to reveal the transparent films, and side etching revealed end faces of the light blocking films at center window and terminal portion boundaries to create visor structured second resist layers that are heat softened as an anticorrosion layer on the revealed faces. |
US08723042B2 |
Flexible flat cable and manufacturing method thereof
A flexible flat cable which includes wire cores, insulation coating layers surrounding the wire cores, shield coating layers surrounding the insulation coating layers, an upper insulation plate layer formed on the shield coating layers, a lower insulation plate layer formed under the shield coating layers and opposite to the upper insulation plate layer, and a shield plate layer formed under the lower insulation plate layer. |
US08723041B2 |
Electric cable comprising a foamed polyolefine insulation and manufacturing process thereof
A process for manufacturing an electric cable including at least one core including a conductor and an insulating coating surrounding the conductor includes the steps of: providing a polyolefin material, a silane-based cross-linking system and a foaming system including at least one exothermic foaming agent in an amount of 0.1% to 0.5% by weight with respect to the total weight of the polyolefin material; forming a blend with the polyolefin material, the silane-based cross-linking system and the foaming system; and extruding the blend on the conductor to form the insulating coating. An electric cable includes at least one core consisting of a conductor and an insulating coating surrounding the conductor and in contact therewith, the insulating coating consisting of a layer of expanded, silane-cross-linked polyolefin material having an expansion degree of 3% to 40%. |
US08723034B2 |
Junction box with improved waterproof seal
A junction box includes a cable connecting box, a cover covering the cable connecting box and an o-ring sealing between the cover and the cable connecting box. The cable connecting box includes an insulative block, a plurality of contacting foils retained in the insulative block, a plurality of diodes connecting with two neighborly contacting foils and four walls surrounding around the insulative block. The cover defines a sealing slot for receiving the o-ring. The sealing slot has a bump at a place of the molding joint of the cover to enlarge a deformation of the o-ring for improving a waterproof effect of the junction box. |
US08723033B2 |
Electric junction box
An electric junction box to prevent stress from working at a junction of conductive pattern of a connector terminal mounted on a printed wiring board and curtail its size, comprises, a printed wiring board, a connector including a terminal connected with a conductive pattern on the printed wiring board, and a connector housing accommodating the terminal, and a cover adapted to receive the printed wiring board therein and including a hole disposed on an outer wall of the cover and passing the connector therethrough. The lower cover is provided with a support adapted to overlap with a part of an edge of the connector housing surrounding the terminal, and position the part between the printed wiring board and the support. |
US08723031B2 |
Terminal box
A terminal box includes: a main body (101); at least one pair of terminal strips (106) which are connectable to a positive electrode and a negative electrode of a solar cell module; and a backflow prevention diode (118) bridged between the terminal strips (106) to connect the terminal strips (106). The terminal strip (106) and the backflow prevention diode (118) are contained in the main body (101). The terminal strip (106) includes: a supporting part (S) for supporting a lead wire (118a) of the backflow prevention diode (118) in a mounted state; a pinching part (K) for supporting the lead wire (118a) in a pinched state; and a recess (119B) which is provided between the supporting part (S) and the pinching part (K) and configured to position a connecting solder upon connecting the lead wire (118a) and the terminal strip (106). |
US08723021B2 |
Efficiency in antireflective coating layers for solar cells
A solar cell includes a substrate having an N-region and a P-region, a first anti-reflective layer disposed on the substrate, a metallic contact disposed on the first anti-reflective layer, a second anti-reflective layer disposed on the first anti-reflective layer and the metallic contact, and a region partially defined by the first anti-reflective layer and the second anti-reflective layer having diffused metallic contact material operative to form a conductive path to the substrate through the first anti-reflective layer, the metallic contact, and the second anti-reflective layer. |
US08723019B2 |
Solar cell and method of manufacturing the same
A solar cell including: a silicon (Si) substrate; a buffer layer disposed on a side of the silicon substrate; a germanium (Ge) junction disposed on a side of the buffer layer opposite the silicon substrate; a first electrode electrically connected to the germanium junction; and a second electrode electrically connected to the germanium junction, wherein the buffer layer has a lattice constant that increases in a direction from the silicon substrate to the germanium junction. |
US08723013B2 |
Musical performance device, method for controlling musical performance device and program storage medium
An object of the present invention is to provide a musical performance device capable of changing layout information, such as information regarding the arrangement of a virtual musical instrument set, by an intuitive operation. In the present invention, when position coordinates detected at a shot timing are within one of the areas of a plurality of virtual pads, a CPU designates a virtual pad in this area as a target of positional change. Then, the CPU determines a position where the virtual pad designated as a target of positional change is placed by this positional change, based on position coordinates detected at shot timings, and changes the position of the virtual pad designated as a target of positional change to the determined position. |
US08723012B2 |
Computer-readable storage medium having information processing program stored therein, information processing apparatus, information processing system, and information processing method
An information processing program executed by a computer of an information processing apparatus that performs processing based on an input from an input device including an acceleration sensor and an angular velocity sensor, is provided, and the information processing program causes the computer to function to set a combined speed indicating a speed based on a movement of the input device, by using acceleration data outputted by the acceleration sensor, and angular velocity data outputted by the angular velocity sensor; and to execute a predetermined process based on the combined speed having been set. |
US08723009B2 |
Drumstick mounted mutable tambourine
A drumstick mountable mutable tambourine comprises a body mountable to the drumstick. A block may be attached to the body on which one or more mutable sound making devices are mountable. A muting device may be capable of actuation for muting the mutable sound making devices. |
US08723007B2 |
Guitar bridge assembly with string-specific saddles and stopbar
A stringed instrument bridge assembly for a stringed instrument having a plurality of strings of different gauges, the bridge assembly including a stringed instrument bridge; and a plurality of string-specific saddles arranged within the stringed instrument bridge. Each of the plurality of string-specific saddles includes a respective notch structured and arranged for accommodating therein a respective string of the plurality of strings. Each of the respective notches is configured in a string-specific manner to accommodate therein a string at least one of: configured to produce a particular note, having specific string gauge, and within a range of string gauges configured to produce a particular note. |
US08723004B1 |
Maize hybrid X08C866
A novel maize variety designated X08C866 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X08C866 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X08C866 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X08C866, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X08C866. This invention further relates to methods for producing maize varieties derived from maize variety X08C866. |
US08723003B2 |
Maize inbred PH1MC3
A novel maize variety designated PH1MC3 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1MC3 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1MC3 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1MC3 or a locus conversion of PH1MC3 with another maize variety. |
US08722997B2 |
Plants and seeds of corn variety CV927887
According to the invention, there is provided seed and plants of the corn variety designated CV927887. The invention thus relates to the plants, seeds and tissue cultures of the variety CV927887, and to methods for producing a corn plant produced by crossing a corn plant of variety CV927887 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV927887 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV927887. |
US08722994B2 |
Plants and seeds of hybrid corn variety CH945438
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH945438. The invention thus relates to the plants, seeds and tissue cultures of the variety CH945438, and to methods for producing a corn plant produced by crossing a corn plant of variety CH945438 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH945438. |
US08722990B2 |
Soybean cultivar S110121
A soybean cultivar designated S110121 is disclosed. The invention relates to the seeds of soybean cultivar S110121, to the plants of soybean cultivar S110121, to the plant parts of soybean cultivar S110121, and to methods for producing progeny of soybean cultivar S110121. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S110121. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S110121, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S110121 with another soybean cultivar. |
US08722987B2 |
Soybean cultivar S100143
A soybean cultivar designated S100143 is disclosed. The invention relates to the seeds of soybean cultivar S100143, to the plants of soybean cultivar S100143, to the plant parts of soybean cultivar S100143, and to methods for producing progeny of soybean cultivar S100143. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S100143. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S100143, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S100143 with another soybean cultivar. |
US08722986B2 |
Soybean cultivar S100106
A soybean cultivar designated S100106 is disclosed. The invention relates to the seeds of soybean cultivar S100106, to the plants of soybean cultivar S100106, to the plant parts of soybean cultivar S100106, and to methods for producing progeny of soybean cultivar S100106. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S100106. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S100106, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S100106 with another soybean cultivar. |
US08722985B2 |
Soybean cultivar S100108
A soybean cultivar designated S100108 is disclosed. The invention relates to the seeds of soybean cultivar S100108, to the plants of soybean cultivar S100108, to the plant parts of soybean cultivar S100108, and to methods for producing progeny of soybean cultivar S100108. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S100108. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S100108, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S100108 with another soybean cultivar. |
US08722983B2 |
Soybean cultivar S110130
A soybean cultivar designated S110130 is disclosed. The invention relates to the seeds of soybean cultivar S110130, to the plants of soybean cultivar S110130, to the plant parts of soybean cultivar S110130, and to methods for producing progeny of soybean cultivar S110130. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S110130. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S110130, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S110130 with another soybean cultivar. |
US08722980B2 |
Soybean cultivar S090059
A soybean cultivar designated S090059 is disclosed. The invention relates to the seeds of soybean cultivar S090059, to the plants of soybean cultivar S090059, to the plant parts of soybean cultivar S090059, and to methods for producing progeny of soybean cultivar S090059. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S090059. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S090059, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S090059 with another soybean cultivar. |
US08722979B2 |
Soybean cultivar 1347284
A soybean cultivar designated 1347284 is disclosed. The invention relates to the seeds of soybean cultivar 1347284, to the plants of soybean cultivar 1347284, to the plant parts of soybean cultivar 1347284, and to methods for producing progeny of soybean cultivar 1347284. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 1347284. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 1347284, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 1347284 with another soybean cultivar. |
US08722975B2 |
Soybean variety D2011901
The invention relates to the soybean variety designated D2011901. Provided by the invention are the seeds, plants and derivatives of the soybean variety D2011901. Also provided by the invention are tissue cultures of the soybean variety D2011901 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety D2011901 with itself or another soybean variety and plants produced by such methods. |
US08722974B1 |
Soybean variety XBP31010
A novel soybean variety, designated XBP31010 is provided. Also provided are the seeds of soybean variety XBP31010, cells from soybean variety XBP31010, plants of soybean XBP31010, and plant parts of soybean variety XBP31010. Methods provided include producing a soybean plant by crossing soybean variety XBP31010 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XBP31010, methods for producing other soybean varieties or plant parts derived from soybean variety XBP31010, and methods of characterizing soybean variety XBP31010. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP31010 are further provided. |
US08722972B1 |
Lettuce variety rawhide
The present invention provides novel lettuce cultivar Rawhide and plant parts, seed, and tissue culture therefrom. The invention also provides methods for producing a lettuce plant by crossing the lettuce plants of the invention with themselves or another lettuce plant. The invention also provides lettuce plants produced from such a crossing as well as plant parts, seed, and tissue culture therefrom. |
US08722969B2 |
Corn event PV-ZMGT32(nk603) and compositions and methods for detection thereof
The present invention provides a recombinant DNA molecule that confers herbicide tolerance to transgenic corn plants. Also provided by the present invention are methods for growing a corn plant that tolerate application of glyphosate comprising planting and growing seeds comprising the recombinant DNA molecule and applying glyphosate to the corn plant. |
US08722968B2 |
Defensin-encoding nucleic acid molecules derived from Nicotiana alata, uses therefor and transgenic plants comprising same
The present invention provides nucleic acid molecules derived from Nicotiana alata, which encode defensin-like molecules. The present invention contemplates the use of such nucleic acid molecules in the generation of transgenic plants having resistance or at least reduced sensitivity to plant pests including insects, microorganisms, fungi and/or viruses and the of the encoded defensin-like molecules in compositions for topical application to a plant or a plant part so as to reduce prevent or reduce infestation of the plant or plant part by plant pests. The transgenic plants provided by the present invention include monocotyledonous and dicotyledonous plants, and particularly include crop plants and ornamental flowering plants. |
US08722965B1 |
Maize hybrid X90C500
A novel maize variety designated X90C500 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X90C500 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X90C500 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X90C500, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X90C500. This invention further relates to methods for producing maize varieties derived from maize variety X90C500. |
US08722964B2 |
Genetically engineered or transgenic rats exhibiting a cancer phenotype due to a disruption of germline tumor suppressor genes
This invention relates to the engineering of animal cells, preferably mammalian, more preferably rat, that are deficient due to the disruption of tumor suppressor gene(s) or gene product(s). In another aspect, the invention relates to genetically modified rats, as well as the descendants and ancestors of such animals, which are animal models of human cancer and methods of their use. |
US08722963B2 |
Absorbent article and components thereof having improved softness signals, and methods for manufacturing
An absorbent article having improved softness signals is disclosed. The article may include a topsheet or a backsheet including a nonwoven web. The web may have a basis weight of 30 gsm or less, may be formed of spunlaid fibers including polyolefin and up to 5 percent by weight TiO2, and may be impressed with a pattern of bond impressions to a bond area percentage of at least 10 percent forming a pattern of bonded regions and raised regions. The web may have opacity of 42 or greater; have an average height difference between bonded regions and raised regions of at least 280 μm; be hydroengorged; and/or have a cross-direction tensile strength of 350 gf/cm. A nonwoven web manufactured to have a suitable combination of such features exhibits an enhanced appearance of softness, soft tactile feel and satisfactory mechanical attributes, while being relatively cost effective. |
US08722962B2 |
Wound dressing applicator
A wound dressing applicator (10) for applying hydrocolloid dressings, compositions for tissue regeneration and the like to a patient's skin. Known wound dressing applicators do not effectively protect against contamination of the wound dressing and/or can be fiddly and difficult to operate and be rendered unusable by unwanted premature separation of the various layers of material adhered to one another. The present applicator comprises a rigid body (20) having a rigid body enclosure (30) for receiving a wound dressing, and an ejector (40) for ejecting the wound dressing from the rigid body enclosure and onto a patient's wound. This enables effective and aseptic handling of a wound dressing and application of the wound dressing onto a patient's wound. |
US08722961B2 |
Hyperbaric dressing
A hyperbaric dressing has a fluid impermeable sheet and a fluid permeable layer with a sheet of porous material positioned between these two layers with passageways to permit fluid to flow out of the dressing. |
US08722957B2 |
Sulfur-based bulk reductants and methods of using same
Provided herein are methods of treating a composition. In one embodiment, the method includes contacting a sulfur-based bulk reductant with a composition that includes soil and/or water and further includes one or more oxidized organic and/or inorganic compounds. In another embodiment, the method includes contacting a sulfur-based bulk reductant with a composition that includes soil and/or water and further includes one or more chlorinated organic compounds. In still another embodiment, the method includes contacting a sulfur-based bulk reductant with a composition that includes soil and/or water and further includes one or more chemical warfare agents. Also provided herein are sulfur-based bulk reductants for use in remediation of contaminated soil and/or water. |
US08722956B2 |
Kit for decomposing organophosphorus compounds
Methods and kits for decomposing organophosphorus compounds in non-aqueous media at ambient conditions are described. Insecticides, pesticides, and chemical warfare agents can be quickly decomposed to non-toxic products. The method comprises combining the organophosphorus compound with a non-aqueous solution, preferably an alcohol, comprising metal ions and at least a trace amount of alkoxide ions. In a first preferred embodiment, the metal ion is a lanthanum ion. In a second preferred embodiment, the metal ion is a transition metal. |
US08722955B2 |
Simulated moving bed separation device
A device (SMB) for separation by simulated moving bed adsorption comprises a plurality of elementary adsorption zones Zi in series operating in a closed loop, and at least one singular adsorption zone with a dead volume which is greater than the adsorption zones Zi, the solid adsorbant of said singular adsorption zone having a granulometry which is lower than that of the solid adsorbant of the ordinary adsorption zones. |
US08722954B2 |
Use of solvent to decrease caustic scrubber fouling
The present invention is a method of reducing the formation of fouling deposits occurring in a caustic scrubber used to remove acid gases comprising: a) providing a caustic scrubber fed with an alkaline aqueous solution comprising essentially one or more of NaOH, KOH or LiOH, b) providing an olefin-containing hydrocarbon stream, contaminated with oxygenated compounds and acid gases, and said oxygenated compounds are capable to make polymeric fouling deposits in the presence of the alkaline solution of the scrubber, c) sending the above hydrocarbon stream to the caustic scrubber to recover an olefin-containing hydrocarbon stream essentially free of acid gases, wherein, d) an efficient amount of a solvent capable to reduce the formation of fouling deposits is introduced in the caustic scrubber and/or in the alkaline solution fed to the scrubber, e) the liquid outlet of the scrubber is sent to means to separate the solvent from the alkaline solution, and wherein the caustic scrubber has several stages with various caustic concentrations, and wherein the solvent injection and removal can be located at each stage. |
US08722953B2 |
Method for producing dienes by hydrodimerization
The invention relates to a process for preparing substituted or unsubstituted 1,7-diolefins by hydrodimerizing non-cyclic olefins having at least two conjugated double bonds in the presence of a reducing agent and of a catalyst, wherein the catalyst used is a metal-carbene complex. |
US08722948B2 |
Method for catalytically processing slurry
In a method for thermal processing of slurry, slurry is combined with a bio-mass to produce a mixture. The mixture is subjected in a heated mixer pump to a cracking temperature, thereby allowing the mixture to catalytically undergo a cracking reaction to produce a reaction mixture which is directly outgased in the mixer pump to produce an outgased portion and a solid portion. The outgased portion and the solid portion are separately discharged from the mixer pump; with the low boiling fraction of the outgased portion allowed to cool down for further processing, and the solid portion collected in a residual matter container for further processing. |
US08722946B2 |
Method for avoiding the generation of by-products during the production of haloalkane compounds
Disclosed is a process for the manufacture of haloalkane compounds, and more particularly, to an improved process for the manufacture of the compound 1,1,1,3,3-pentachloropropane (HCC-240fa), which mitigates the formation of by-products. The present invention is also useful in the manufacture of other haloalkane compounds such as HCC-250 and HCC-360. One embodiment of the process comprises a method and system for avoiding the formation of polyvinyl chloride during the production of HCC-240fa from CCl4, in which vinyl chloride (VCM) is fed into a reactor as a vapor instead of as a liquid, using a diffusing device to further increase the contact surface between VCM vapor and CCl4. |
US08722945B2 |
Method for pretreating and regenerating catalysts used in a process for making fluoroiodoalkanes
A process for the preparation of a fluoroiodoalkane represented by the structural formula CF3(CF2)n—I, wherein n is 0 or 1. The process has the step of reacting a source of iodine with a compound represented by the structural formula CF3(CF2)n—Y, wherein Y is selected from H, Cl, Br and COOH and wherein n is 0 or 1. The reaction is carried out at a temperature from about 100° C. to about 750° C. and at a pressure from about 0.001 to about 100 atm for a contact time from about 0.001 second to about 300 hours in the presence a catalyst. The catalyst is subject to one or both of the following: (a) treating the catalyst prior to the reaction via contact with a gas selected from the group consisting of hydrogen fluoride, trifluoromethane, hydrogen, hydrogen iodide, iodine, fluorine, and oxygen, wherein the contact is carried out at a temperature and for a contact time sufficient to reduce the length of the induction period of the catalyst; and (b) treating the catalyst after the reaction via contact with a gas selected from the group consisting of hydrogen fluoride, hydrogen, fluorine, oxygen, or air at a temperature and for a contact time sufficient to regenerate the catalyst. |
US08722942B2 |
Method for producing biphenyl derivative
A method produces a biphenyl derivative, with an industrially high yield and excellent productivity, by use of a raw material which is low in cost and toxicity. The method for producing the biphenyl derivative represented by Formula (1) is characterized in that a chlorine atom in a benzene derivative represented by Formula (2) reacts with magnesium metal to convert the benzene derivative into a Grignard reagent, and then the Grignard reagent is subjected to a coupling reaction in the presence of a catalyst and a dichloropropane: (wherein A represents at least one selected from alkyl groups, alkoxy groups, alkoxymethyl groups, a vinyl group, phenyl groups and chlorine, and n represents an integer of 1 to 4). |
US08722932B2 |
Method for separating a mixture comprising three components by simulated moving bed chromatography
A method for separating a mixture of components by simulated moving bed chromatography: (1) feeding the simulated moving bed such that the eluting power of the liquid phase in the second zone is greater than that of the liquid phase in the third zone, trapping the target component inside the second and the third zone; (2) a solvent for dissolving the mixture to be separated, instead of the feeding solution, is fed into the simulated moving bed through the feeding port, and the eluting power of the liquid phase in the second zone is maintained greater than that of the liquid phase in the third zone, thereby both the pre-impurity and the post-impurity are rinsed off completely, and the target component trapped in the second and the third zone is further purified; and (3) the target component trapped in the simulated moving bed is rinsed off the bed. |
US08722925B2 |
Squaramide derivatives as CXCR2 antagonist
The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described. |
US08722924B1 |
Integrated ethanol and biodiesel facility
An integrated facility for the co-production of ethanol and biodiesel fuel is provided. Ethanol and corn oil, the primary product and a by-product from the ethanol plant, are utilized as feedstocks for a biodiesel plant operating within the same general facility as the corn ethanol plant. By-products of the biodiesel plant, principally crude liquid glycerol and gaseous ethanol or methanol, are recycled to various parts of the ethanol plant. |
US08722917B2 |
Boron-containing small molecules
This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate. |
US08722910B2 |
Diyne compositions
A novel class of diyne compounds and diyne salts provided herein are effective and potent Ole1 protein inhibitors, useful for treating fungal pathogens. Compounds, fungicides and methods are provided as novel, potent and broad spectrum anti-fungal agents for treatment against a wide variety of fungal pathogens in humans and animals, and in the agricultural setting. |
US08722907B2 |
Production process of glycolide
The invention provides a production process of glycolide comprising the respective steps of: Step 1 of heating a mixture containing a glycolic acid oligomer and a high boiling polar organic under normal or reduced pressure to reflux the mixture and at that time, conducting a total reflux operation in a reflux time within a range of 0.1 to 20 hours under conditions that substantially the whole amount of a distillate distilled out of a reflux system containing the mixture is refluxed into the reflux system; Step 2 of heating the mixture after the total reflux operation or a mixture obtained by adding the high boiling polar organic solvent to a glycolic acid oligomer component recovered from the mixture after the total reflux operation to conduct depolymerization; and Step 3 of collecting glycolide from a co-distillate. |
US08722906B2 |
(E)-N-monoalkyl-3-oxo-3-(2-thienyl) propenamine and process for producing the same and process for producing (E,Z)-N-monoalkyl-3-oxo-3-(2-thienyl) propenamine
The present invention provides a process for producing (E)-N-monoalkyl-3-oxo-3-(2-thienyl)propenamine represented by Formula (1); wherein R is a C1-4 alkyl, the method comprising the steps of: maintaining a solution containing (Z)—N-monoalkyl-3-oxo-3-(2-thienyl)propenamine dissolved therein at 25° C. or below to deposit crystals and separating crystals having a particle diameter of 100 μm or less from the deposited crystals; and a process for producing (E,Z)—N-monoalkyl-3-oxo-3-(2-thienyl)propenamine comprising the steps of: reacting an alkali metal salt of β-oxo-β-(2-thienyl)propanal with a monoalkylamine compound; adding a water-insoluble organic solvent to the resulting reaction mixture; adding seed crystals containing (E)-N-monoalkyl-3-oxo-3-(2-thienyl)propenamine to an organic layer obtained by conducting separation; and keeping the resulting mixture at 25° C. or below. |
US08722904B2 |
Anthracene derivative, light-emitting device and electronic appliance
A novel anthracene derivative with a large energy gap is provided. An anthracene derivative represented by General Formula (G1) below is provided. In the formula, Ar1 and Ar2 independently represent an aryl group with 6 to 13 carbon atoms in a ring, R1 and R2 independently represent any of hydrogen, an alkyl group with 1 to 4 carbon atoms, or an aryl group with 6 to 13 carbon atoms in a ring, and each of Ar1, Ar2, R1, and R2 may have a substituent and the two substituents may be bonded to each other to form a ring. |
US08722901B2 |
Carboxy oxazole or thiazole compounds as DGAT-1 inhibitors useful for the treatment of obesity
Heteroaryl compounds, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or disorders mediated by Diacylglycerol acyltransferase (DGAT) enzyme, particularly DGAT-1 is described. |
US08722899B2 |
Desferrithiocin polyether analogues
Compounds represented by structural formulas described herein, such as Structural Formula (I): or a pharmaceutically acceptable salt thereof are useful in treating conditions such as metal overload, oxidative stress, and neoplastic and preneoplastic conditions. |
US08722897B2 |
Metal complexes of thiourea and derivatives as metal delivering anti-cancer and anti-inflammatory agents
The present invention relates to metal thiourea complexes comprising N-substituted thiourea ligands and sulfur-coordinated metal ions, and methods for using the metal thiourea complexes for delivering otherwise unstable or impermeable metal ions to mammalian cells, for inhibiting cancer cell growth and inflammation, and for inhibiting the activities of associated drug targets under in vitro and in vivo conditions. The metal complexes of N-substituted thiourea are defined by the following formula (Ia or Ib) wherein R1 can be H, alkyl, alkenyl, alkynyl, aryl or heterocyclic groups; R2 can be H, alkyl, alkenyl, alkynyl or aryl groups; n=1 to 4; X− is a pharmaceutically acceptable anion (chloride, bromide, iodide, hexafluorophosphate, or triflate) and M is a coinage metal (Au, Ag, or Cu). |
US08722896B2 |
Prokineticin receptor antagonists and uses thereof
Contemplated compounds, compositions, and methods of prokineticin antagonists are presented where a prokineticin antagonist is used in the treatment and prevention of various conditions and disorders, and especially type II diabetes. |
US08722893B2 |
Process for manufacturing 5-chloromethyl-2,3-pyridine dicarboxylic acid anhydrides
A process for manufacturing 5-chloromethyl-2,3-pyridine dicarboxylic acid anhydrides (I) wherein Z is hydrogen or halogen; Z1 is hydrogen, halogen, cyano or nitro; comprising the steps of (i) reacting a compound of formula (II), wherein the symbols have the meaning given in formula (I), with a chlorinating agent, optionally in the presence of a radical initiator in a solvent selected from halogenated hydrocarbons, and (ii) crystallizing the compound (I) formed in step (i) from a solvent selected from chlorobenzene, 1,2-dichlorobenzene, 1,3-dichlorobenzene, 1,4-dichlorobenzene, dichloroethane, trichloromethane, dichloromethane, toluene, xylenes, ethyl acetate, methyl tert.-butyl ether, and mixtures thereof. Compounds (I) are useful intermediates in the synthesis of herbicidal imidazolinones. |
US08722892B2 |
Processes and intermediates for preparing a macrocyclic protease inhibitor of HCV
The present invention relates to synthesis procedures and intermediates of a compound of formula: and the salts thereof. |
US08722889B2 |
Azaindoles useful as inhibitors of JAK and other protein kinases
The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. |
US08722883B2 |
Pyrimidine sulphonamide derivatives as chemokine receptor modulators
A compound of formula (I), or a pharmaceutically acceptable salt, solvate or in vivo hydrolysable ester thereof and pharmaceutical compositions comprising these, all for use in the treatment of chemokine mediated diseases and disorders. |
US08722881B2 |
Method of synthesis of tetradentate amide macrocycle ligand and its metal-complex
A tetradendate amide based macrocyclic ligand and its Fe(III) complex which act as activators of hydrogen peroxide. The synthetic methodology to develop the ligands is new, simple and provides better yield for each step of the ligand synthesis. The Fe(III)-complexes and hydrogen peroxide together are can perform several environmentally benign oxidation reactions. Organic dye bleaching, bleaching of pulp and paper effluent and N-oxide synthesis may be performed using the newly developed catalyst and hydrogen peroxide. Alcohol oxidation and alkene epoxidation may also be performed using the catalysts and hydrogen peroxide. |
US08722878B2 |
Biomass hydrolysis
High-yielding method for chemical hydrolysis of lignocellulose into monosaccharides. The process of the invention can additionally be applied to cellulose, xylan and related biomass polysaccharides, such as galactan, mannan, or arabinan. The method is employed for hydrolysis of a biomass polysaccharide substrate. The process is carried out in an ionic liquid in which cellulose is soluble in the presence of catalytic acid at a temperature sufficiently high to initiate hydrolysis. Water is added to the reaction mixture after initiation of hydrolysis at a rate controlled to avoid precipitation yet avoid undesired sugar dehydration products such ad HMF. Hydrolysis product is useful as feedstock for fermentations including fermentation processes for ethanol, butanol and other fuels. |
US08722871B2 |
VMP-like sequences of pathogenic borrelia species and strains
The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies. |
US08722869B2 |
Class of therapeutic protein based molecules
The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides compounds having an anchoring domain that anchors the compound to the surface of a target cell, and a therapeutic domain that can act extracellularly to prevent infection of a target cell by a pathogen, such as a virus. The present invention also comprises therapeutic compositions having sialidase activity, including protein-based compounds having sialidase catalytic domains. Compounds of the invention can be used for treating or preventing pathogen infection, and for treating and reducing allergic and inflammatory responses. The invention also provides compositions and methods for enhancing transduction of target cells by recombinant viruses. Such compositions and methods can be used in gene therapy. |
US08722868B2 |
Glycosyltransferase, novel glycosyltransferase gene, and novel sugar donor compound
An object of the present invention is to provide a sugar donating reagent comprising a sugar donor compound other than a sugar nucleotide and an enzyme capable of catalyzing a glycosyl transfer reaction using a sugar donor compound other than a sugar nucleotide. The present invention provides the following: a sugar donating reagent containing a compound of formula (A): wherein R1 is independently selected from hydrogen, or C1-6 alkyl, C2-6 alkenyl, and C2-6 alkynyl in which each of the groups is unsubstituted or substituted with one or more groups selected from OH, F, Cl, Br, I, CN, NO2, and SO2, n is 0, 1, 2, 3, 4 or 5, m is 0 or 1, and X represents a monosaccharide bound via a β bond on its anomeric carbon; a glycosyltransferase capable of catalyzing a glycosyl transfer reaction using the sugar donor; and a glycosyltransferase gene comprising DNA encoding the glycosyltransferase. |
US08722859B2 |
Multivalent antibodies and uses therefor
The present application describes engineered antibodies, with three or more functional antigen binding sites, and uses, such as therapeutic applications, for such engineered antibodies. |
US08722857B2 |
Anti-CD79B antibodies and immunoconjugates and methods of use
The present invention is directed to cysteine-engineered anti-CD79b antibody, huMA79b.v28, and compositions of matter thereof useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same. |
US08722856B2 |
Anti-MUC1 antibody
An object of the present invention is to provide an antibody which does not bind to a normal cell, and is specific for a cancer cell. The object was solved by the finding by the present inventors that an antibody obtained by immunizing an animal using a 2,3ST glycopeptide as an antigen unexpectedly recognizes a sugar chain specific for a cancer specifically and remarkably, and consequently, can recognize and kill a cancer cell expressing MUC1 having such a cancer cell-specific sugar chain. The present invention provides, for example, an antibody, an antigen-binding fragment thereof or a MUC1-binding molecule, in which specificity for a cancer-associated structure of MUC1 is 100-fold or more as compared with that for a normal tissue-associated structure of MUC1. |
US08722852B2 |
Cosmetic composition for stimulating the synthesis of proteins of the basement membrane
Cosmetic composition which can be applied topically, comprising at least one compound of the general formula (I) in which R1 is H, C1-C20-alkyl, cycloalkyl or aryl-C1-C4-alkyl, n is 1-4, X is —O—, —NH— or —NR2— and R2H or C1-C20-alkyl; and at least one compound corresponding to the above formula (I) but in which XR1 with X having the possible meaning of —NH— is the residue of an alpha-amino acid; use of these compounds and of the composition for stimulating the synthesis of the proteins of the basement membrane; and also both those compounds of the formula (I) in which X is —NR2— and both R1 and R2 are different from H, and the compounds corresponding to formula (I) but in which XR1 with X having the possible meaning of —NH— is the residue of an alpha-amino acid, as such. |
US08722851B2 |
Analgesia with minimal tolerance and dependence by a mu opioid receptor agonist that also binds filamin A
A composition and method are disclosed that utilize an isolated polypeptide or analog thereof to inhibit the interaction of a mu-opioid receptor with filamin A. A contemplated polypeptide has an amino acid residue sequence illustrated by the formula: W-[X1X2X3 . . . X43X44X45]nValAlaX48GlyLeu[X51X52X53 . . . X94X95X96]m-Y, wherein the various elements are defined elsewhere. A contemplated method can be used to select a VAKGL-binding compound. |
US08722850B2 |
Self-assembling peptides and their use in the formation of hydrogels
There is described a group of novel self-assembling peptides (SAPs), comprising biotinylated and unbiotinylated sequences, hybrid peptide-peptoid sequences, branched sequences for a total of 48 tested motifs, showing a heterogeneous ensemble of spontaneously self-assembled structures at the nano- and microscale, ranging from short tabular fibers to twisted ribbons, nanotubes and hierarchical self-assembled micrometer-long sheets. Specifically, the SAPs according to the present invention which initially spontaneous assemble, surprisingly form stable solid scaffolds upon exposure to neutral pH buffer. Further these SAPs allow adhesion, proliferation and differentiation of murine and human neural stem cells and have self-healing propensity. They also did not exert toxic effects in the central nervous system, can stop bleeding and foster nervous regeneration. Therefore, the SAPs according to the present invention are improved biomaterials, a highly valid and useful alternative which may replace the known SAPs, thus overcoming the disadvantages related thereto. |
US08722845B2 |
Polylactide resin having excellent heat resistance and preparation method thereof
The present invention relates to a polylactide resin having excellent heat resistance, a preparation method thereof, and a polylactide resin composition including the same.The polylactide resin is characterized by high polymerization activity owing to an organic coordinated metal catalyst even though it has a low catalyst content, and a molecular weight reduction due to thermal decomposition at high temperature and a rate of thermal decomposition including depolymerization are greatly suppressed by a low catalyst content and a low resin acidity, and thus provided is the polylactide resin having superior heat resistance. |
US08722843B2 |
Material for fiber manufacturing and fiber
Disclosed is a material for fiber manufacturing comprising a liquid crystal polyester satisfying the following requirements (a) and (b):(a) the weight-average molecular weight is equal to or less than 30000 and the polydispersity is equal to or less than 2.5; and(b) the melt viscosity measured at 360° C. with conditions of a nozzle pore diameter of 0.5 mm and a shear velocity of 1000 s−1 using a flow feature testing machine is equal to or less than 70 Pa·s. |
US08722842B2 |
Optical film and image display device
The present invention provides an optical film exhibiting wavelength dispersion such that a retardation value is smaller on the shorter wavelength side, and capable of being also formed comparatively thinly.The optical film of the present invention is an optical film including a polyimide-based polymer represented by the following general formula (I).In the formula (I), m is 40% by mol or more and 100% by mol or less. R1 and R2 each independently denote a substituent having a carbon-carbon double bond or a triple bond. A, A′, B, B′, E, G, and H each denote a substituent, and small letters corresponding to these alphabets denote substitution number thereof. X and Y each independently denote bond part such as a covalent bond. The substituents having a carbon-carbon double bond or a triple bond represented by R1 and R2 are a substituted or unsubstituted aryl group, a substituted or unsubstituted vinyl group, and a substituted or unsubstituted ethynyl group. |
US08722839B2 |
Poly(phenylene ether) fiber and method of making
A fiber comprises a composition including a poly(phenylene ether) having less than or equal to 240 parts per million by weight of hydroxyl groups associated with ethylene bridge groups and less than or equal to 800 parts per million by weight of hydroxyl groups associated with rearranged backbone groups, both amounts based on the weight of the poly(phenylene ether). Fiber of low denier can be formed from this composition. The fiber can be formed by melt spinning. |
US08722836B2 |
Siloxane nitrones and use thereof
The invention relates to the production of nitrone-bearing siloxanes and their use as additives for radiation-curable coatings. |
US08722835B2 |
One component polysiloxane coating compositions and related coated substrates
Disclosed are one-component low temperature, moisture curable, storage stable coating compositions that include a silanol-functional silicone and/or an alkoxy-functional silicone, a flexibilizer comprising a reaction product of two or more reactants, and a curing agent selected from amines, aminosilanes, ketimines, aldimines, and combinations thereof. Particular compositions include of said silicones, a flexibilizer comprising a polymer having an alkoxysilane terminal unit as well as a urethane linkage, and a combination of an aminosilane, a trifunctional oxysilane and an aminoalcohol. Also disclosed are substrates at least partially coated with a coating deposited from such a composition and methods for coating substrates with such compositions. |
US08722834B2 |
Equilibration of siloxanes on water-containing sulphonated cation exchange resins
The invention relates to a process for producing equilibration products of organosiloxanes by rearrangement of the siloxane bond to a cation exchange resin, the organopolysiloxanes thus obtainable, and the use thereof. |
US08722821B1 |
Method of making polyolefin with a silicon nitride nano-filler
The method of making polyolefin with a silicon nitride nano-filler uses silicon nitride (SiN) as a promoter for in situ polymerization with a zirconocene catalyst. The method includes adding the bis(cyclopentadienyl) zirconium dichloride catalyst and nanoparticles of silicon nitride to a reactor. The reactor is then charged with toluene and a methylaluminoxane co-catalyst, and is heated for a period of time sufficient to bring the reactor to a polymerization reaction temperature. Nitrogen gas is removed from the reactor following the heating, and then ethylene monomer is fed into the reactor, initiating polymerization. The polymerization is then quenched, and non-reacted monomer is vented. The polyolefin product is then removed from the reactor, washed and dried. |
US08722813B2 |
Resin composition
A resin composition containing: an ester compound including a carboxylic acid ester obtained by using (1) a monohydric alcohol having an alkyl group having 1 to 4 carbon atoms; (2) a dicarboxylic acid having an alkylene group having 2 to 4 carbon atoms; and (3) a dihydric alcohol having an alkylene group having 2 to 6 carbon atoms, the ester compound having an acid value of 1.00 mgKOH/g or less, a hydroxyl value of 5.0 mgKOH/g or less, and a number-average molecular weight of from 300 to 700; and an aliphatic polyester. Since the resin composition of the present invention inhibits the generation of volatile compounds, the resin composition can be suitably used in various industrial applications, such as daily sundries, household electric appliance parts, and automobile parts. |
US08722810B2 |
Modified high CIS conjugated diene copolymer and preparing method of the same
A modified conjugated diene copolymer and a preparing method for the same are provided. The method comprising a polymerization step for polymerizing conjugated diene monomers to form a conjugated diene polymer; and a modifying step for reacting the conjugated diene polymer with a modifier to form a modified conjugated diene polymer. The modifier includes a polythiol ester compound, a polythiol alkane compound or a combination thereof, the polythiol ester compound has a chemical formula (I): Ra-(O—C(═O)Rb-SH)x (I). The polythiol alkane compound has a chemical formula (II): HS—(CH2)m—(Rd)nCH2SH (II). |
US08722809B2 |
Process for preparing end-modified vinylidene fluoride elastomer
The present invention provides a preparation process for converting to a vinylidene fluoride elastomer having a group having sulfinic acid, sulfinic acid derivative, sulfonic acid or sulfonic acid derivative at one end or both ends of its trunk chain, and the preparation process provides a vinylidene fluoride elastomer having, at one end or both ends of its trunk chain, end groups represented by the formula: —CR1R2—CR3R4—SO2H, wherein R1 to R4 may be the same or different and each is hydrogen atom or fluorine atom, by allowing a vinylidene fluoride elastomer having, at one end or both ends of its trunk chain, end groups represented by the formula: —CR1R2—CR3R4—X1, wherein R1 to R4 are as defined above, X1 is bromine atom or iodine atom, to react with a sulfur compound represented by the formula: (M1)nH2-nS2O4, wherein M1 is a monovalent or divalent metal ion or ammonium ion, n is an integer of 0 to 2. |
US08722808B2 |
Polyolefin compositions having low gloss
Polyolefin composition comprising, in percent by weight: A) 10-50% of a copolymer of propylene with one or more comonomer(s) selected from ethylene and CH2═CHR alpha-olefins where R is a 2-8 carbon alkyl, which copolymer contains from 1 to 8% of comonomer(s); B) 50-90% of a blend of copolymers (bI) and (bII), wherein copolymer (bI) contains from 18 to 40% of ethylene, and copolymer (bII) contains from 55 to 85% of ethylene, and the weight ratio (bI)/(bII) is from 0.2 to 2; in which composition the copolymer component (bI) is present in amounts of 15% or more with respect to the total weight of (A)+(B), the weight ratio C2II/C2I of the content C2II of ethylene in copolymer component (bII) to the content C2I of ethylene in copolymer component (bI) is of 1.8 or more, and the intrinsic viscosity [η] of the fraction XS soluble in xylene at room temperature (about 25° C.), referred to the total weight of (A)+(B), is of 2 dl/g or more. |
US08722804B2 |
Polymer blends and films made therefrom
Polymer blends and films made therefrom are provided. The polymer blend can include a first polyethylene having a density of less than about 0.940 g/cm3, a melt index (I2) greater than 0.75 g/10 min, and a melt index ratio (I21/I2) of less than 30. The polymer blend can also include a second polyethylene having a density of less than about 0.940 g/cm, a melt index (I2) of less than 1 g/10 min, a melt index ratio (I21/I2) greater than 30, and a molecular weight distribution (Mw/Mn) of less than 4.5. |
US08722803B2 |
Polyolefinic compositions
A polymer composition comprising (per cent by weight): a) 70-84% of a crystalline propylene polymer having an amount of isotactic pentads (mmmm), measured by 13C-MNR on the fraction insoluble in xylene at 25° C., higher than 97.5 molar %; b) 8-15% of an elastomeric copolymer of ethylene and propylene, the copolymer having an amount of recurring units deriving from ethylene ranging from 25 to 50 wt % and being partially soluble in xylene at ambient temperature; the polymer fraction soluble in xylene at ambient temperature having an intrinsic viscosity value ranging from 2.5 to 3.5 dl/g; and c) 8-15% of ethylene homopolymer having an intrinsic viscosity value ranging from 1.5 to 4 dl/g; said composition having a value of melt flow rate ranging from 55 to 90 g/10 min, and the amount of hexane extractables lower than 3.5 wt %. |
US08722798B2 |
Thermosettable composition containing a combination of an amphiphilic block copolymer and a polyol and a thermoset product therefrom
A thermosettable composition including (a) at least an amphophilic block copolymer, (b) at least a polyol, (c) at least an epoxy resin containing an average at least 2 oxirane rings per molecule, (d) at least an anhydride hardener containing an average at least 1 anhydride ring per molecule, and (e) at least a catalyst; and a thermoset product prepared from said thermosettable composition. |
US08722797B2 |
Cellulose fibers crosslinked with low molecular weight phosphorous containing polyacrylic acid and method
A crosslinked cellulose fiber that has been crosslinked with a low molecular weight polyacrylic acid crosslinking agent, having phosphorous incorporated into the polymer chain and a method of crosslinking the fiber. |
US08722796B2 |
Process for preparing an aqueous polymer dispersion
Process for preparing an aqueous polymer dispersion with small polymer particles. |
US08722795B1 |
Dry-erase surface composition and method of applying
A dry erase writing surface is formed from a single component, 100% solids polyurethane, ambient cured, dry erase paint composition having at least ninety percent by weight low NCO isocyanate, a cure accelerating catalyst and a defoaming agent. The surface is ready for use in a day. The composition can additionally contain a diluent, vegetable oil or mineral spirits. The coating has a VOC of between 0 and 49 g/l. The coating is initially applied to the surface of the substrate to form a film thickness of 1-3 mils. The whiteboard is characterized as when tested by erasure of the dry erase markers, the marks are virtually invisible after 2500 cycles. The composition can be packaged as a kit with applicators. |
US08722792B1 |
Dry-erase surface composition and method
A dry erase writing surface is formed from a single component, 100% solids polyurethane, ambient cured, dry erase paint composition having at least ninety percent by weight low NCO isocyanate, a cure accelerating catalyst and a defoaming agent. The surface is ready for use in a day. The composition can additionally contain a diluent, vegetable oil or mineral spirits. The coating has a VOC of between 0 and 49 g/l. The coating is initially applied to the surface of the substrate to form a film thickness of 1-3 mils. The whiteboard is characterized as when tested by erasure of the dry erase markers, the marks are virtually invisible after 2500 cycles. The composition can be packaged as a kit with applicators. |
US08722790B2 |
Heat-sealable polyolefin films
Heat-sealable polyolefin film made of or comprising at least one layer of a polyolefin composition comprising (percent by weight): A) 20% to 80% of a heterophasic polyolefin composition comprising: AI) 3% to 30% by weight of a crystalline olefin polymer fraction; AII) 70% to 97% by weight of an elastomeric fraction comprising at least an elastomeric copolymer of propylene or ethylene with 12 to 88% by weight of at least one α-olefin of formula H2C═CHR, where R is H or a C2-C10 linear or branched alkyl, optionally containing 0.5 to 5% by weight of a diene, and having solubility in xylene at room temperature greater than 50% by weight; B) 20% to 80% of at least one filler. |
US08722789B2 |
Poly(arylene ether) composition, method, and article
A composition includes specific amounts of a virgin poly(arylene ether) resin and a rubber-modified polystyrene that is preferably derived from post-consumer recycling. The composition includes about 0.2 to about 1.5 weight percent of polymerized acrylonitrile residue that can originate as a contaminant in the recycled rubber-modified polystyrene. The composition avoids the need for compatibilizing agents required by related compositions. |
US08722785B2 |
Process for producing EVOH composite
Provided is a composite of saponified product of an ethylene-vinyl ester-based copolymer from which films excellent in gas barrier properties and film rigidity and highly inhibited from having fish eyes are obtained.It is a process for producing a composite of saponified product of an ethylene-vinyl ester-based copolymer, which comprises: mixing a composition (a) containing a saponified product of ethylene-vinyl ester-based copolymer (A1) and having a moisture content of 50% by weight or higher with a water-swellable layered inorganic compound (B) to obtain a composition (C); and mixing the composition (C) in the state of having a moisture content of 10% by weight or higher and less than 60% by weight with a saponified product of ethylene-vinyl ester-based copolymer (A2). |
US08722784B2 |
Polymer nanocomposite
A polymer nanocomposite comprises a polymer; and a nanoparticle derivatized to include functional groups including carboxy, epoxy, ether, ketone, amine, hydroxy, alkoxy, alkyl, aryl, aralkyl, alkaryl, lactone, functionalized polymeric or oligomeric groups, or a combination comprising at least one of the forgoing functional groups. The variability in tensile strength and percent elongation for the polymer nanocomposite is less than the variability of these properties obtained where an underivatized nanoparticle is included in place of the derivatized nanoparticle. |
US08722783B2 |
Fiber reinforced composite material
The present disclosure relates to a fiber reinforced composite material. In an embodiment, the composite material includes a PLLA fiber material and a matrix material that does not have the same chemical element composition as the fiber material. Other fiber reinforced composite materials are also disclosed. |
US08722781B2 |
Rubber composition for tire and pneumatic tire made therefrom
A rubber composition for a tire containing 100 parts by weight of a rubber, 1 to 30 parts by weight of a polyether (E1) having the formula (I): R1—{(OCH2CH2CH2CH2)m(OA)n—OH}q (I) wherein R1 is a residue of a C1 to C24 compound having 1-6 hydroxyl groups, from which at least one hydroxyl group is removed, A Ls a C2 to C24 alkylene group other than a 1,4-butylene group, q is an integer of 1 to 6, and m and n are independently integers of 1 to 600, and/or the derivative thereof (E2) and 10 to 180 parts by weight of a filler, which is excellent in processability, silica dispersability abrasion resistance and wet braking performance, etc. |
US08722779B2 |
Thermoplastically processible aminoplastic resin, thermoset microfibre non-wovens, and process and plant for their production
The invention relates to a thermoplastic processible aminoplast resin, a method for its production and a fine fiber non-woven material as textile area of fibers from aminoplast resins, in particular duroplastic triazine resins, which have an average fiber diameter of 0.1 to 100 μm and between 1 and 1000 branching arms and between 1 and 300 branching points per square millimeter. The invention also relates to a method for production of duroplastic fine fiber non-woven material in which a melt of melamine resin is pressed through spinning nozzles and blown by the escaping hot air to fine fibers, the fine fibers are separated from the air stream and deposited to a non-woven material consisting of a tangled layer, a treatment with a media causing cross-linking and a neutralization step follows, and the fine fibers are glued to a non-woven material in a subsequent thermal after-treatment, whereat the thermal after-treatment comprises two steps. |
US08722776B2 |
Graft polymer and thermoreversibly cross-linked bitumen composition comprising said graft polymer
The disclosure relates to a bitumen/polymer composition comprising at least one bitumen and at least one graft polymer, the grafts enabling the bitumen/polymer compositions to be thermoreversibly cross-linked. The disclosure also relates to the use of said bitumen/polymer compositions in fields of application relating to roads, especially in the production of asphalt binders, and in industrial fields of application. The disclosure further relates to the method for producing said thermoreversibly cross-linked bitumen/polymer compositions. |
US08722772B2 |
Hydraulically setting sealing composition
The invention provides hydraulically setting sealing composition based on a) a hydraulically setting compound out of the group comprising high-alumina cement, ordinary portland cement, blast furnace slag, b) protective-colloide stabilized polymer of one or more ethylenically unsaturated monomers in form of an aqueous polymer dispersion or a water-redispersible polymer powder, and c) one or more fillers. |
US08722768B2 |
Liquid resin composition and semiconductor device
According to the invention, a liquid resin composition which has favorable wet spreadability after mounting of a chip and exhibits excellent solder cracking resistance even in a high-temperature solder reflow process at about 260° C., i.e., even when being used in lead-free solder, and a semiconductor package using the liquid resin composition are provided. In the liquid resin composition of the invention, an acrylic copolymer having a radical polymerizable functional group contains alkyl(meth)acrylate as a constituent monomer having a linear or branched alkyl group having 6 to 9 carbon atoms in an amount of 10 wt % to 40 wt % of the entire constituent monomers. |
US08722764B2 |
Nanoparticle/vinyl polymer composites
Vinyl polymers formed by bulk or solution polymerization techniques are combined with nanoparticles to produce aqueous dispersions of nanoparticle/vinyl polymer composites. |
US08722763B2 |
Masterbatch and process for preparing a polymer composition
The present invention relates to a process for preparing a polymer composition by using a masterbatch, as well as a process, wherein said polymer composition is used for preparing an article, preferably a cable. Also a masterbatch, a polymer composition comprising the masterbatch, and an article, preferably a cable, comprising the polymer composition are provided. |
US08722756B2 |
Aqueous emulsion polymers, their preparation and use
The present invention provides aqueous emulsion polymers comprising (A) monomers A (B) at least one (meth)acrylate with olefinically unsaturated side groups (monomers B), and (C) at least one photoinitiator, and also the use thereof in coating materials, more particularly in exterior architectural paints. |
US08722754B2 |
Extruded foams made with polylactides that have high molecular weights and high intrinsic viscosities
This invention provides an economical process for extruding a PLA resin into a low density foam with a high closed cell content. Excellent quality, low density foam is produced easily and reproducibly. The PLA resin in the foam has a weight average molecular weight of at least 500,000 and an intrinsic viscosity of at least 1.4 deciliters/gram. |
US08722753B2 |
Hydroxyl terminated precursor and method of making the same
A method of making a hydroxyl terminated precursor for polyurethane is disclosed. The method comprises heating a vegetable oil-polyol mixture of modified vegetable oil containing about two or more hydroxyl groups per molecule and a polyether polyol having about two or more hydroxyl groups per molecule at a temperature of at least about 25 degrees Celsius and at a pressure of about 1 atmosphere. The mixture has a hydroxyl equivalent ratio of about 1:1 vegetable oil to polyol. The method further comprises mixing for at least about 10 minutes an isocyanate containing about two or more isocyanato groups per molecule at least about 25 degrees Celsius to the vegetable oil-polyol mixture at a molar equivalent ratio of at least 2:1 vegetable oil-polyol mixture to isocyanate to react the isocyanate with the mixture to form the hydroxyl terminated precursor. |
US08722747B2 |
Vessel for containing catalyst in a tubular reactor
In a catalyst carrier for insertion in a tube of a reactor, an annular container holds the catalyst in use and has a perforated inner wall defining a tube, a perforated outer wall, a top surface closing the annular container and a bottom surface closing the annular container. A surface closes the bottom of the tube formed by the inner wall of the annular container. A skirt extends upwardly from the perforated outer wall of the annular container from a position at or near the bottom surface to a position below the location of a seal located at or near the top surface and extending from the container by a distance which extends beyond an outer surface of the skirt. |
US08722746B2 |
Hydroxyphenyl derivatives and biological applications thereof
The invention relates to hydroxyphenyl derivatives of formula (I); and uses thereof as anti-bacterial and/or anti-parasitic agents. |
US08722738B2 |
Acetycysteine compositions and methods of use thereof
A pharmaceutical composition and method for providing a reduction in side effects for human patients in need of therapy comprising the administration of a pharmaceutical composition comprising acetylcysteine is disclosed. |
US08722735B2 |
Pharmaceutical compositions having desirable bioavailability
The present invention is directed to the provision of pharmaceutical compositions. The compositions include a therapeutic agent and a relatively low amount of surfactant for providing higher bioavailability of the therapeutic agent. The compositions are particularly desirable as ophthalmic compositions in which the therapeutic agent is a prostaglandin such as travoprost and the surfactant is a vegetable oil such as castor oil. |
US08722734B2 |
Composition for inhibition of cathepsin K
The present invention relates to the a method of inhibiting bone resorption in a mammal in need thereof with an oral pharmaceutical composition comprising a cathepsin K inhibitor, or a pharmaceutically acceptable salt thereof, or a mixture thereof, according to a continuous schedule having a dosage interval of once weekly, biweekly, twice monthly or once monthly. |
US08722728B2 |
Composition and method for treating dry eye syndrome
The present invention provides for compositions, medicaments, and methods for treating or alleviating the symptoms of dry eye syndrome or chronic dry eye. More specifically, the present embodiments provide for medicaments consisting of tocopherol or tocotrienol eyedrops. A single topical administration of tocopherol or tocotrienol eyedrops in the eyes of a subject suffering from dry eye alleviates symptoms for at least one day. In particular, the eyedrop medicament consists of α-tocopheryl acetate; α-tocopheryl acetate and about 0.5% aqueous component; or α-tocopheryl acetate, about 2.5% tocopherol emulsifier, and about 20% to about 30% aqueous excipient. |
US08722727B2 |
Antifungal agents
Novel derivatives of enfumafungin are disclosed herein, along with' their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and method of using such compounds as antifungal agents and/or inhibitors of (1,3)-β-D-glucan synthase. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs, as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating and/or preventing fungal infections and associated diseases and conditions. |
US08722726B2 |
Substituted arylcyclopentenes as therapeutic agents
Disclosed herein is a compound of the formula Therapeutic methods, compositions, and medicaments, related thereto are also disclosed. |
US08722725B2 |
Caffeoylquinic acid derivatives containing nitrogen, and preparation method, pharmaceutical composition and usage thereof
The present invention provides caffeoylquinic acid derivatives and a method of preparing for the same, and also provides pharmaceutical compositions containing caffeoylquinic acid derivatives, and uses of caffeoylquinic acid derivatives in preparation of a medicament for the treatment or prophylaxis of virus diseases, in particular, uses of respiratory syncytial virus and hepatitis B virus, which has the characteristics of safety, high effectiveness and low toxicity. |
US08722724B2 |
Compositions and methods for treating neoplastic diseases
Disclosed herein are compositions and methods for treating neoplastic diseases. Included are compositions and methods that are effective against multiple myeloma cells resistant to conventional and bortezomib treatment. Furthermore, combination treatment with two different proteosome inhibitors is shown to be synergistic for treating multiple myeloma. |
US08722720B2 |
Imidazole derivatives as IDO inhibitors
Presently provided are IDO inhibitors of general formulae (VII), (VIII) as shown below and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated immunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosupression associated with an infectious disease. |
US08722714B2 |
Oxazolidine derivatives as NMDA antagonists
The present invention provides therapeutically active oxazolidine derivatives and compositions as NMDA antagonists, which are useful in preventing and treating central nervous system disorders by inhibiting over-activation of NMDA receptors. In one aspect, the present invention provides methods of treating and/or preventing neurodegenerative diseases and neuropathological disorders, methods of providing neuroprotection under stress conditions such as a stroke, and methods of enhancing the brain's cognitive functions in mammals and humans. For example, the compounds can prevent glutamate-induced neuro-toxicity by inhibiting the activities of the NMDA receptor in the presence of toxic doses of NMDA. In addition, the compounds can potentiate the calcium current in the presence of low dose of NMDA. |
US08722712B2 |
Substituted aryl 1 ,2,4-oxadiazoles derivatives as sphingosine-1 phosphate receptors modulators
The present invention relates to substituted aryl 1,2,4-oxadiazoles derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors. |
US08722709B2 |
Mineralocorticoid receptor antagonists
Mineralocorticoid receptor antagonists, of which the following is exemplary. |
US08722706B2 |
Two phase bioactive formulations of bis-quaternary pyridinium oxime sulfonate salts
The present invention relates to two phase systems of a bioactive ingredient in particle form that has limited or no solubility in a liquid medium, which provides stability to the bioactive ingredient that is similar to the bioactive ingredient when in the solid state. The bioactive ingredient may be capable of therapeutically treating for the presence of a cholinesterase inhibitor. The bio active ingredient comprises 1,1′-methlyenebis[4-[(hydroxyimino)methyl]-pyridinium]dimethanesulfonate. |
US08722700B2 |
CCI-779 formulations for parenteral administration
This invention provides CCI-779 cosolvent concentrates which are useful in preparing a parenteral formulation of rapamycin 42-ester with 3-hydroxy-2-(hydroxymethyl)-2-methylpropionic acid (CCI-779) following admixture with a diluent. |
US08722699B2 |
Iso-ergoline derivatives
Provided herein are novel iso-ergoline derivatives and compositions thereof. In other embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders such as, for example, migraine using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of agonizing receptors such as, for example, the 5-HT1D and/or the 5-HT1B receptor, without agonizing the 5-HT2B receptor using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing or inhibiting activity at receptors such as, for example, the adrenergic alpha2A and/or the alpha2B receptors using the compounds and compositions disclosed herein. |
US08722697B2 |
Pharmaceutical composition for treating hypertension and metabolic syndrome and use thereof
The present invention provides a pharmaceutical composition comprising the following active ingredients: 1) amlodipine or a pharmaceutically acceptable salt thereof, 2) pioglitazone or a pharmaceutically acceptable salt thereof, and 3) rosuvastatin or a pharmaceutically acceptable salt thereof. The present invention also provides use of the pharmaceutical composition in preparing a medicament for treating hypertension or metabolic syndrome. The pharmaceutical composition of the present invention can treat hypertension or metabolic syndrome, while effectively controlling the incidence of associated cardiovascular diseases and more potently improving survival prognosis in hypertensive patients. When blood pressure is lowered to desired level, the risk factors such as cardiovascular diseases are rectified, metabolic disorders and prognosis of patients are improved, and survival rate of hypertensive patients is raised. |
US08722696B2 |
Process for preparing particles containing an antiviral
A process for preparing a particle comprising a co-precipitate surrounding a neutral hydrophilic carrier, said process comprising spraying an organic solution on a neutral hydrophilic carrier, said solution comprising at least one triazine or pyrimidine active ingredient having HIV inhibiting properties, one surface active agent, and one hydrophilic polymer, wherein the spraying of whole of the solution occurs in at least two separate steps, each of these steps followed by a grinding step of the product obtained at the end of the preceding step. |
US08722694B2 |
Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them
The present invention relates to bicyclic heterocycles of general formula wherein Ra to Rc, A to E and X are defined as in claim 1, the tautomers, stereoisomers and salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases which have valuable pharmacological properties, in particular an inhibitory effect on signal transduction mediated by tyrosine kinases, their use in the treatment of diseases, especially tumoral diseases and diseases of the lungs and airways, and the preparation thereof. |
US08722693B2 |
Salts of the Janus kinase inhibitor (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
The present invention provides salt forms of (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile that are useful in the modulation of Janus kinase activity and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases. |
US08722691B2 |
Azolopyrimidines as inhibitors of cannabinoid 1 activity
The invention provides compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1). The compounds are of the Formulae Ia, Ic, Ig and Ik: |
US08722690B2 |
Mesoionic pesticides
Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein X is O or S; Y is O or S; A is O, S, NR3e or C(R3c)═C(R3d); Z is a direct bond, O, S(O)n, NR6, C(R7)2O, OC(R7)2, C(═X1), C(═X1)E, EC(═X1), C(═NOR8) or C(═NN(R6)2); a is 1, 2 or 3; and R1, R2, R3a-R3e, R4, R5, R6, R7, R8, X1 and E are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention. |
US08722688B2 |
Compounds for the treatment of hepatitis C
The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV. |
US08722686B2 |
Hydroxamic acid derivatives useful as antibacterial agents
The invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof, thereof, wherein: G is a group of formula (II); and pharmaceutically acceptable salts, prodrugs, hydrates, or solvates, thereof, wherein A, B. L1-L4 A, B, R1-R4 and m are as defined herein. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and their use in treating a bacterial infection. |
US08722684B2 |
1-[2-(2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment
1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients. |
US08722680B2 |
Method of treating neurodegenerative diseases
The present invention relates to a method of treating a patient suffering from a disorder of the central nervous system associated with 5-HT1A receptor subtype, comprising as an active ingredient a carbostyril derivative or a salt thereof represented by the formula (1) wherein the carbon-carbon bond between 3- and 4-positions in the carbostyril skeleton is a single or a double bond. |
US08722675B2 |
Method of treatment or prophylaxis
The present invention is directed to methods and agents that are useful in the prevention and amelioration of signs and symptoms associated with neuropathic conditions. More particularly, the present invention discloses the use of angiotensin II receptor 2 (AT2 receptor) antagonists for the treatment, prophylaxis, reversal and/or symptomatic relief of neuropathic pain, including mechanical hyperalgesia, thermal or mechanical allodynia, diabetic pain and entrapment pain, in vertebrate animals and particularly in human subjects. The AT2 receptor antagonists may be provided alone or in combination with other compounds such as those that are useful in the control of neuropathic conditions. |
US08722674B2 |
1,3,5-triazine-2,4,6-triamine compound or pharmaceutical acceptable salt thereof, and pharmaceutical composition comprising the same
Disclosed herein are a 1,3,5-triazine-2,4,6-triamine compound or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a composition for preventing or treating metabolic syndromes, diabetes, or cancers with deletion of P53 gene, which comprises the same. |
US08722673B2 |
Imine compounds for combating invertebrate pests
The present invention relates to imine compounds which are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds. |
US08722672B2 |
Topical pharmaceutical composition including rel-N-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4′-(trifluoromethoxY)-[1,1′-biphenyl]-3-carboxamide
The present invention relates to pharmaceutical compositions of 2-Methyl-4′-trifluoromethoxy-biphenyl-3-carboxylic acid [6-(cis-2,6-dimethyl-morpholin-4-yl)-pyridin-3-yl]-amide, to the use of such compositions in therapeutic applications and to methods for manufacturing such compositions. |
US08722669B2 |
Compounds and methods of treating ocular disorders
A method of treating an ocular disorder in a subject associated with aberrant all-trans-retinal clearance in the retina, the method comprising administering to the subject a therapeutically effective amount of a primary amine compound of formula: wherein R1 is an aliphatic and/or aromatic compound. |
US08722667B2 |
Compositions and methods for inhibiting the proliferation of cells
The present invention relates to chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides benzodiazepine derivatives and methods of using benzodiazepine derivatives as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, and hyperproliferation, and the like. |
US08722663B2 |
Di-substituted pyridine derivatives as anticancers
The present invention provides a novel compound having an excellent antitumor effect. The compound of the present invention is represented by the following general formula (1) wherein R1 and R2 are aryl or the like; A is lower alkylene; Ring X is optionally substituted arylene; E is bond or lower alkenylene; Ring Y is optionally substituted heterocycloalkylene containing one or more nitrogen atoms, one of which is attached to the adjacent carbonyl group; G is —NH-G2-, —N(lower alkyl)-G2-, —NH—CH2-G2-, —N(lower alkyl)-CH2-G2- or —CH2-G2-, [wherein G2 binds to R2, G2-R2 is bond-R2, phenylene-G3-R2, phenylene-G4-O—R2, phenylene-G5-NH—R2, phenylene-G6-N(lower alkyl)-R2 or quinolinediyl-O—R2, the phenylene of said phenylene-containing groups being optionally substituted with one or more substituents; G3-R2 is —O-lower alkylene-R2 or the like; G4-O— is lower alkylene-O— or the like; G5 is lower alkylene; G6 is lower alkylene]. |
US08722662B2 |
Heterocyclic compounds
Provided is a compound having a monoamine reuptake inhibitory activity, which is represented by the formula (I) wherein ring A is an optionally substituted 6-membered aromatic ring, ring B is the substituents on ring A are optionally bonded to form, together with ring A, an optionally substituted 9- or 10-membered aromatic fused ring, and other symbols are as defined in the specification, or a salt thereof. |
US08722661B2 |
Pyrrolopyrimidone and pyrrolopyridone inhibitors of tankyrase
There are provided compounds of the formula (I) wherein Q, R1 and R2 are defined herein. The compounds have activity as anticancer agents. |
US08722659B2 |
Quinazolinedione derivatives, preparation thereof and various therapeutic uses thereof
The subject matter of the invention is quinazolinedione derivatives of formula (I), methods for obtaining same and therapeutic uses thereof, such as cancer, diabetes, muscle diseases, bone diseases, cardiovascular diseases, central nervous system diseases, peripheral nervous system diseases, inter alia. |
US08722658B2 |
Azetidinyl diamides as monoacylglycerol lipase inhibitors
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein. |
US08722655B2 |
Macrocyclic urea and sulfamide derivatives as inhibitors of tafia
The invention relates to compounds of the formula (I) which are inhibitors of activated thrombin-activable fibrinolysis inhibitor. The compounds of the formula I are suitable for producing medicaments for prophylaxis, secondary prevention and treatment of one or more disorders associated with thromboses, embolisms, hypercoagulability or fibrotic changes. |
US08722653B2 |
Method for treating uterine fibroids
The invention relates to a method for treating uterine fibroids, which method comprises administering to a patient in need thereof, an effective amount of 17α-acetoxy-11β-[4-N,N-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20-dione (ulipristal) or any metabolite thereof. More particularly, the method is useful for reducing or stopping bleeding in a patient afflicted with uterine fibroids, and/or for reducing the size of uterine fibroids. |
US08722648B2 |
Liquid pharmaceutical form of alkylphosphocholine and method for preparing same
The inventions relates to a liquid pharmaceutical form containing an active ingredient alkylphosphocholines and a co-solvent system. The co-solvent system is mixture from hexylene glycol, propylene glycol, diethylene glycol monoethyl ether and water. The pharmaceutical form having a pH value in the range of 4 to 6, which if it is necessary can be achieved by adding a pH adjuster. The composition has a good storage stability and it is suitable for local application on the different organs of the body. The inventions relates also to a method for producing the same pharmaceutical form. |
US08722641B2 |
Oligonucleotides which inhibit p53 induction in response to cellular stress
The present invention relates to novel oligonucleotides which comprise p53 5′-UTR sequence TCCCTGG (SEQ ID NO: 1) or the complementary p53 3′-UTR sequence CCAGGGA (SEQ ID NO: 2) and their use for such therapeutic applications as protection of normal tissues from the toxicities of chemical or radiation exposure; reducing tissue damage in hypoxia-reperfusion injury, neurodegenerative disorders, oxidative stress, injuries, hyperthermia; preventing aging; preservation of tissues and organs prior to transplanting, etc. |
US08722640B2 |
Stabilized STAT3 decoy oligonucleotides and uses therefor
The present invention is based, at least in part, on novel, unimolecular STAT3 oligonucleotide decoys exhibiting increased in vivo stability as compared to previously known decoys which are effective in inhibiting STAT3 when administered systemically. The invention is also based on pharmaceutical compositions comprising these unimolecular decoys, and methods for using these decoys in the treatment of cancer. |
US08722636B2 |
Animal treatments
Compositions and methods for the treatment and control of various conditions in an animal which comprises administering to said animal an effective amount of a immediate release composition of about 0.5% to 50% wt/wt of active ingredient together with excipients to a total of about 100%, wherein said compositon dissolves in a relatively short period of time, e.g., 75 seconds or less, 5 seconds or less, or 3 seconds or less, upon administration to said animal. |
US08722634B2 |
Use of compounds extracted from Momordica charantia L. in the manufacture of medicaments for prevention and treatment of diabetes and obesity
The present invention disclosed a medical use of cucurbitane triterpenoids represented by the following formula and isolated from Momordica charantia L. of Cucurbitaceae family in the preparation of medications for prevention and treatment of diabetes and obesity. The above cucurbitane triterpenoids may be acted as a glucose uptake stimulator, an agonist for the translocation of glucose transporter 4 (GLUT4) to the cell membrane, and an activator of adenosine monophosphate-activated protein kinase (AMPK). They may have potential for the prevention and treatment of diabetes and obesity. |
US08722631B2 |
Soluble tumor necrosis factor receptor treatment of medical disorders
The invention pertains to methods and compositions for treating medical disorders characterized by elevated levels or abnormal expression of TNFα by administering a TNFα antagonist, such as recombinant TNFR:Fc. |
US08722630B2 |
Use of apolipoproteins to decrease inflammation
The invention features methods of using serum factors such as Apolipoprotein A2 and Apolipoprotein C3 for reducing or preventing a chronic or acute inflammatory response (e.g., an inflammatory response due to an autoimmune disease or an injury). |
US08722629B2 |
Auristatin derivatives and use thereof
The present application relates to novel derivatives of monomethylauristatin F, to processes for preparing these derivatives, to the use of these derivatives for treating and/or preventing diseases, and also to the use of these derivatives for preparing medicaments for treating and/or preventing diseases, more particularly hyperproliferative and/or angiogenic disorders such as, for example, cancerous disorders. Such treatments may be practised as a monotherapy or else in combination with other medicaments or further therapeutic measures. |
US08722627B2 |
Proteasome-activating lightening peptidic hydrolyzates and compositions containing them
A peptidic hydrolyzate enriched in bioactive peptides is disclosed that is a proteasome activator. Cosmetic and pharmaceutical compositions are disclosed that include the peptidic hydrolyzate enriched in bioactive peptides in a physiologically acceptable medium. Also disclosed are methods for depigmenting, lightening and/or whitening the skin and treating hyperpigmentation blemishes as well as cutaneous signs due to photo-aging by administering the cosmetic compositions or pharmaceutical compositions. |
US08722625B2 |
Treatment of cardiovascular disorders using the cell differentiation signaling protein Nell1
It has been identified in accordance with the present invention that Nell1 is essential for normal cardiovascular development by promoting proper formation of the heart and blood vessels. The present invention therefore provides therapeutic methods for treating cardiovascular disorders by employing a Nell1 protein or nucleic acid molecule. |
US08722621B2 |
Stabilized insulin-like growth factor polypeptides
The invention relates to stabilized polypeptides having an IGF-1 sequence and an Ea peptide sequence, where the natural physiological cleavage of the Ea peptide from the IGF-1 is prevented. |
US08722620B2 |
Insulin derivatives
The present invention is related to insulin derivatives having a side chain attached to an ε-amino group of a Lys residue present in the A-chain or to an ε-amino group of a Lys residue in the B-chain. |
US08722619B2 |
Antifungal agents and uses thereof
The invention features echinocandin class compounds. The compounds can be useful for the treatment of fungal infections. |
US08722618B2 |
IL4/IL13 binding repeat proteins and uses
IL4/IL13-binding proteins comprise binding domains, which inhibit IL4/IL13 binding to IL4Ralpaha and common gamma chain complexes (Type 1) and inhibit IL4 binding to IL4Ralpha and IL13Ralpha1 complexes (Type 2), and IL13 binding to IL13Ralpha1 and/or IL13Ralpha2, are useful in the treatment of cancer, inflammatory, and other pathological conditions, such as allergic or fibrotic conditions, especially pulmonary conditions. |
US08722614B2 |
Adiponectin production enhancer
The present invention relates to an adiponectin production enhancer comprising sericin as an active ingredient, and to a pharmaceutical composition and food and drink comprising sericin. These are effective in the prevention and/or amelioration of various diseases caused by reduction of blood adiponectin level such as arteriosclerosis, fatty liver and diabetes associated with obesity. The enhancer, the pharmaceutical composition and the food and drink according to the invention have excellent adiponectin production enhancing effects as well as high safety and are expected to be broadly applied to a variety of pharmaceutical preparations and food and drink. |
US08722610B2 |
Auto-emulsifying cleaning systems and methods for use
An auto-emulsifying cleaning composition capable of emulsifying upon contact with water, the composition in one typical embodiment comprising, based on the total weight of the composition, (a) from about 1% to about 99% by weight a blend of dibasic esters; (b) from about 1% to about 40% by weight of a blend of surfactants consisting of an organic anion neutralized with an organic cation, where either or both of the anion and the cation have surfactant properties, and the complex of which is soluble in the dibasic ester solvent blend. The blend of surfactants is typically a cationic surfactant and an anionic surfactant, which may or may not be used in conjunction with non-ionic surfactants. The dibasic esters are be derived from a blend of adipic, glutaric, and succinic diacids, and, in one particular embodiment, the blend comprises dialkyl adipate, dialkyl methylglutarate and dialkyl ethylsuccinate, wherein the alkyl groups individually comprise a C1-C12 hydrocarbon group. |
US08722608B2 |
Process of bleaching
The present invention concerns bleaching of substrates with an aqueous solution of a water soluble salt of a preformed transition metal catalyst together with hydrogen peroxide. |
US08722604B2 |
Stable liquid cleansing compositions comprising critical window of partially hydrogenated triglyceride oil of defined iodine value
The present invention provides personal wash compositions where partially hydrogenated triglyceride oil (defined by IV of 20 to 100) are specifically formulated to provide low temperature stability. Specifically when formulated to have specific concentration of partially hydrogenated triglycerides, delivered alone or as part of mixture with other oils, desirable low temperature stability of formulations is achieved. |
US08722603B2 |
Toilet soap with improved lather
The present invention relates to soap bars having improved lather. Specifically, by limiting amounts of myristic acid and keeping specifically defined ratios of sum of C8-C10 fatty acids to C12 fatty acid bars having substantially improved lather and unexpectedly obtained. |
US08722601B2 |
Polyalkyl (meth)acrylate copolymers having outstanding properties
Copolymers are obtainable by polymerizing a monomer composition composed of a) 0% to 40% by weight of one or more ethylenically unsaturated ester compounds of the formula (I), b) 10% to 99.9% by weight of one or more ethylenically unsaturated ester compounds of the formula (II), c) 0% to 80% by weight of one or more ethylenically unsaturated ester compounds of the formula (III), d) 0.1% to 30% by weight of one or more ethylenically unsaturated, polar ester compounds of the formula (IV), e) 0% to 50% by weight of comonomer, based in each case on the total weight of the ethylenically unsaturated monomers. |
US08722598B2 |
Grease composition for bearings with improved heat-resistant acoustic life
The invention provides a grease composition having (A) a lithium soap thickener, (B) as a base oil an ester type synthetic oil obtainable from an esterification reaction of trimethylolpropane with a fatty acid, and (C) (c-1) a 1-naphthylamine type antioxidant and (c-2) a diphenylamine type antioxidant, wherein the contents of (c-1) and (c-2) are 1.0 to 10 mass % in total, based on the total mass of the composition, and the ratio by mass of (c-1) to (c-2) is in the range from 30:70 to 70:30. |
US08722591B2 |
Biodiesel lighter fluid
Disclosed is an environmentally conscious, odor-free lighter fluid mixture comprising a 50-70% ethanol and 30-50% biodiesel combination. Methyl-ester, ethyl-ester and propyl-ester fatty acids, commonly referred to as biodiesel, are clean burning fuels derived from new or waste vegetable oil such as soybean, canola or sunflower. Combined with an ethanol accelerant, the mixture provides a lighter fluid that is easily ignitable without risk of detonation or explosion, and one that brings charcoal briquettes up to temperature quicker than traditional methods. The mixture is petroleum free, which eliminates the associated unpleasant odors and potential health risks of traditional lighter fluid, including a reduction in the emission of volatile organic compounds (VOCs) into the environment. The mixture offers a renewable, sustainable, and efficient ignition source for charcoal that does not sacrifice utility compared to traditional lighter fluid, and does not impart undesirable flavors onto grilled food. |
US08722589B2 |
Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability
The invention provides for the use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters, preparable by esterifying alcohols having from 1 to 100 hydroxyl groups with 1-alkyl-5-oxopyrrolidine-3-carboxylic acid, in amounts of from 0.01 to 2% by weight for preventing the formation of gas hydrates in aqueous phases which are in contact with a gaseous, liquid or solid organic phase. |
US08722583B2 |
Method for selecting a chemical entity from a tagged library
Disclosed is a method for determining the identity of a chemical entity having a preselected property. The chemical entity is identified from a library composed of a plurality of different chemical entities each appended to unique identifier tags. An anti-tag having the capability of specifically interacting with the unique identifier tag is recovered during the method and used for identification purposes. |
US08722581B2 |
Alkoxylated alkylamine quaternary surfactants for glyphosate
The present invention relates to stable glyphosate formulations with improved efficacy by a highly effective alkoxylated alkylamine quaternary surfactant at a very low used level. The alkoxylated alkylamine quaternary surfactant is compatible in all salts of glyphosate formulations (including potassium and ammonium) EVEN AT VERY HIGH CONCENTRATION (470-600 g a.e./l). |
US08722578B2 |
Spiroheterocyclic pyrrolidinedione herbicidal compositions
Herbicidal compositions containing as active ingredients spiroheterocyclic pyrrolidine dione compounds. |
US08722572B2 |
Metal catalyst substrate and its manufacturing method
A metal catalyst substrate 1 is equipped with a honeycomb body 2 in which a corrugated metal foil 4 and a flat metal foil 5 are multiply rolled, their leader portions being overlapped with each other. A restricting portion 8 is formed at a core portion 7 of the honeycomb body 2 by a portion of the core portion being deformed to restrict flow of exhaust gas in a core portion 7. |
US08722571B2 |
Process to prepare adsorbents from organic fertilizer and their applications for removal of acidic gases from wet air streams
The invention is directed to an adsorbent comprising: a) 20-30% porous carbon with incorporated organic nitrogen species; and b) 70-80% inorganic matter. The invention is directed to a method of making an adsorbent which comprises: a) thermally drying dewatered sewage sludge to form granulated organic fertilizer; and b) pyrolyzing said the organic fertilizer at temperatures between 600 and 1000° C. The invention is additionally directed to the process of removing acidic gases from wet air streams comprising putting an adsorbent in contact with the wet air stream and allowing the adsorbent to adsorb the acidic gases. |
US08722566B2 |
Honeycomb body having a metallic foil with an oxide coat, foil having an oxide coat and method for producing an oxide coat on a metallic foil
A honeycomb body, in particular a catalyst carrier body, includes metallic foil of high-temperature corrosion-resistant steel with connecting points and an oxide layer with a thickness of 60 to 80 or 70 to 75 nm on each surface. The foil is composed of steel with chromium and aluminum components, particularly 1 to 5% aluminum. The oxide layer is substantially aluminum oxide or γ-aluminum oxide with a uniform thickness having a tolerance of less than 10% or less than 5% on all surfaces. The oxide layer may be on a rolled foil having a mean surface roughness of greater than 0.3 or 0.5 μm or approximately 0.6 μm in rolling direction and/or transversely thereto. The honeycomb body is durable under high loads and has defined connecting points. A foil having an oxide coat and a method for producing an oxide coat on a metallic foil are also provided. |
US08722565B2 |
Method for applying a wash coat suspension to a carrier structure
A method for applying a washcoat suspension to a support structure. To provide coatings with largely uniform thickness starting from washcoat suspensions, the method uses a device (10) set up to produce, by means of a process gas (40), a fluid bed of support structures in which the support structures circulate elliptically or toroidally, the method comprising the steps of: a) charging the device (10) with support structures and producing a support-structure fluid bed by means of a process gas (40), wherein the support structures circulate in the fluid bed elliptically or toroidally, preferably toroidally; b) impregnating the support structures with a washcoat suspension by spraying the support structures circulating elliptically or toroidally in the fluid bed with the washcoat suspension; c) drying the support structures sprayed with the washcoat suspension; and d) optionally calcining the support structures loaded with the solids contents of the washcoat suspension. |
US08722559B2 |
Method of suppressing increase in SO2 oxidation rate of NOx removal catalyst
In a NOx removal catalyst used for removing nitrogen oxide in flue gas, when a silica (Si) component as an inhibitor that causes an increase in an SO2 oxidation rate accumulates on a surface of the NOx removal catalyst, the silica component accumulating on the surface of the NOx removal catalyst is dissolved, thereby regenerating the catalyst. Accordingly, the inhibitor such as the silica component covering the surface of the NOx removal catalyst can be removed, thereby enabling to provide a catalyst without having an increase in the SO2 oxidation rate of the regenerated NOx removal catalyst. |
US08722556B2 |
Recovery of slurry unsupported catalyst
A method of recovering unsupported fine catalyst from heavy oil comprises combining a slurry comprising unsupported fine catalyst in heavy oil with solvent to form a combined slurry-solvent stream. The combined slurry-solvent stream is filtered in a deoiling zone. A stream comprising unsupported fine catalyst and solvent is recovered from the deoiling zone. Unsupported fine catalyst is separated from the stream comprising unsupported fine catalyst and solvent. The deoiling zone can comprise a membrane that is rapidly displaced in a horizontal direction. |
US08722553B2 |
Woven airbag fabric
A woven airbag fabric includes a first type of filament yarn, at least a second type of filament yarn and a silicone-based coating. The first type of filament yarn is chosen from the group of polyolefin filament yarns. The at least a second type of filament yarn is chosen from the group of polyamide and polyester filament yarns. |
US08722552B2 |
Woven/knit fabric with reversible air premeability and production process thereof
This woven/knit fabric contains composite yarn comprising a multifilament yarn A2 and a multifilament yarn B2, which satisfies the following conditions (1) to (3): (1) the ratio (WA2/DA2) of the yarn length of the multifilament fiber A2 during absorption of moisture and humidity (WA2) to the yarn length of the multifilament yarn A2 under conditions of 20° C. and 65% humidity (DA2) is 1.02 to 1.30; (2) the ratio (WA2/DB2) of the yarn length of the multifilament yarn A2 during absorption of moisture and humidity (WA2) to the yarn length of the multifilament yarn B2 under conditions of 20° C. and 65% humidity (DB2) is 0.9 to 1.1; and (3) the drying shrinkage stress (DS value) of the multifilament yarn A2 is 0.08 cN/dtex or more. |
US08722537B2 |
Multi-sacrificial layer and method
MEMS devices and methods for utilizing sacrificial layers are provided. An embodiment comprises forming a first sacrificial layer and a second sacrificial layer over a substrate, wherein the second sacrificial layer acts as an adhesion layer. Once formed, the first sacrificial layer and the second sacrificial layer are patterned such that the second sacrificial layer is undercut to form a step between the first sacrificial layer and the second sacrificial layer. A top capacitor electrode is formed over the second sacrificial layer, and the first sacrificial layer and the second sacrificial layer are removed in order to free the top capacitor electrode. |
US08722533B2 |
Semiconductor device and manufacturing method thereof
A manufacturing method of a semiconductor device includes forming a structure comprising an interlayer dielectric layer on a substrate, an ultra-low-k material layer on the interlayer dielectric layer and a plug. The plug passes through the interlayer dielectric layer and the ultra-low-k material layer, and is formed of a first metal material. The method further includes removing an upper portion of the plug by etching to form a recessed portion, and filling the recessed portion with a second metal material. According to the method, contact-hole photolithography is performed only once, and thus avoids alignment issues that may occur when contact-hole photolithography needs to be performed twice. |
US08722531B1 |
Barrier layer for copper interconnect
A method for forming an interconnect structure includes forming a dielectric layer overlying a substrate, forming a metal-containing layer in the dielectric layer, forming a barrier layer overlying the metal-containing layer, and performing a thermal process to form a metal oxide layer underlying the conductive layer. The metal oxide layer is a barrier layer formed at the boundary between the dielectric layer and the metal-containing layer. |
US08722529B2 |
Double solid metal pad with reduced area
An integrated circuit structure includes a bond pad; an Mtop pad located directly underlying the bond pad; an Mtop-1 pad having at least a portion directly underlying the Mtop pad, wherein at least one of the Mtop pad and the Mtop-1 pad has a horizontal dimension smaller than a horizontal dimension of the bond pad; a plurality of vias interconnecting the Mtop pad and the Mtop-1 pad; and a bond ball on the bond pad. Each of the Mtop pad and the Mtop-1 pad has positive enclosures to the bond ball in all horizontal directions. |
US08722527B2 |
Integrated circuit manufacturing method and integrated circuit
The present invention discloses an integrated circuit (IC) comprising a bond pad (160); a substrate stack carrying a first layer (130) comprising conductive regions (135); and an interconnect layer (140) over the first layer (130) comprising a dielectric material portion (400) between the bond pad (160) and the substrate stack, said portion comprising a plurality of air-filled trenches (345) defining at least one pillar (340) of the dielectric material (400), at least said air-filled trenches (345) being capped by a porous capping layer (440). The interconnect layer (140), which typically is one of the uppermost interconnect layers of the IC, has an improved resilience to pressure exerted on the bond pad (160). The present invention further teaches a method for manufacturing such an IC. |
US08722518B2 |
Methods for protecting patterned features during trench etch
A method is provided for forming a monolithic three dimensional memory array. The method includes forming a first memory level above a substrate, and monolithically forming a second memory level above the first memory level. The first memory level is formed by forming first substantially parallel conductors extending in a first direction, forming first pillars above the first conductors, each first pillar including a first conductive layer or layerstack above a vertically oriented diode, the first pillars formed in a single photolithography step, depositing a first dielectric layer above the first pillars, etching first trenches in the first dielectric layer, the first trenches extending in a second direction. After etching, a lowest point in the trenches is above a lowest point of the first conductive layer or layerstack, and the first conductive layer or layerstack does not include a resistivity-switching metal oxide or nitride. Numerous other aspects are provided. |
US08722514B2 |
Semiconductor devices having insulating substrates and methods of formation thereof
In one embodiment, a semiconductor device includes a glass substrate, a semiconductor substrate disposed on the glass substrate, and a magnetic sensor disposed within and/or over the semiconductor substrate. |
US08722510B2 |
Trench-filling method and film-forming system
A method of filling a trench comprises heating a semiconductor substrate having a trench formed therein and an oxide film formed at least on the sidewall of the trench and supplying an aminosilane gas to the surface of the substrate so as to form a seed layer on the semiconductor substrate, heating the semiconductor substrate having the seed layer formed thereon and supplying a monosilane gas to the surface of the seed layer so as to form a silicon film on the seed layer, filling the trench of the semiconductor substrate, which has the silicon film formed thereon, with a filling material that shrinks by burning, and burning the semiconductor substrate coated by the filling material filling the trench in an atmosphere containing water and/or a hydroxy group while changing the filling material into a silicon oxide and changing the silicon film and the seed layer into a silicon oxide. |
US08722507B2 |
Method for forming identification marks on silicon carbide single crystal substrate, and silicon carbide single crystal substrate
A method for forming an identification mark on a silicon carbide single crystal substrate according to the present invention includes: (a) scanning a principal surface of a silicon carbide single crystal substrate with a laser beam at a first energy density such that a groove is formed in the principal surface of the silicon carbide single crystal substrate, thereby forming an identification mark which is constituted of one or more grooves in the principal surface of the silicon carbide single crystal substrate; and (b) scanning an inside of the groove formed in the principal surface of the silicon carbide single crystal substrate with a laser beam at a second energy density that is lower than the first energy density. |
US08722505B2 |
Semiconductor capacitor with large area plates and a small footprint that is formed with shadow masks and only two lithography steps
A semiconductor capacitor with large area plates and a small footprint is formed on a semiconductor wafer by forming an opening in the wafer, depositing a first metal atoms through a first shadow mask that lies spaced apart from the wafer to form a first metal layer in the opening, a dielectric layer on the first metal layer, and a second metal atoms through a second shadow mask that lies spaced apart from the wafer to form a second metal layer on the dielectric layer. |
US08722498B2 |
Self-aligned fin transistor formed on a bulk substrate by late fin etch
Non-planar transistors, such as FinFETs, may be formed in a bulk configuration in the context of a replacement gate approach, wherein the semiconductor fins are formed during the replacement gate sequence. To this end, in some illustrative embodiments, a buried etch mask may be formed in an early manufacturing stage on the basis of superior process conditions. |
US08722491B2 |
Replacement metal gate semiconductor device formation using low resistivity metals
Embodiments of the present invention relate to approaches for forming RMG FinFET semiconductor devices using a low-resistivity metal (e.g., W) as an alternate gap fill metal. Specifically, the semiconductor will typically comprise a set (e.g., one or more) of dielectric stacks formed over a substrate to create one or more trenches/channels (e.g., short/narrow and/or long/wide trenches/channels). A work function layer (e.g., TiN) will be provided over the substrate (e.g., in and around the trenches). A low-resistivity metal gate layer (e.g., W) may then be deposited (e.g., via chemical vapor deposition) and polished (e.g., via chemical-mechanical polishing). Thereafter, the gate metal layer and the work function layer may be etched after the polishing to provide a trench having the etched gate metal layer over the etched work function layer along a bottom surface thereof. |
US08722484B2 |
High-K dielectric stack and method of fabricating same
A method for improving the reliability of a high-k dielectric layer or a high-k dielectric stack by forming an amorphous high-k dielectric layer over an insulating layer, doping the amorphous high-k dielectric layer with nitrogen atoms, and subsequently heating the resulting structure at a temperature greater than or equal to the crystallization temperature of the high-k dielectric material, thereby transforming the high-k dielectric material from an amorphous state to a crystalline state, and causing nitrogen atoms to diffuse into the insulating layer. |
US08722482B2 |
Strained silicon carbide channel for electron mobility of NMOS
A semiconductor is formed on a (110) silicon (Si) substrate, with improved electron mobility. Embodiments include semiconductor devices having a silicon carbide (SiC) portion in the nFET channel region. An embodiment includes forming an nFET channel region and a pFET channel region in a Si substrate, such as a (110) Si substrate, and forming a silicon carbide (SiC) portion on the nFET channel region. The SiC portion may be formed by ion implantation of C followed by a recrystallization anneal or by epitaxial growth of SiC in a recess formed in the substrate. The use of SiC in the nFET channel region improves electron mobility without introducing topographical differences between NMOS and PMOS transistors. |
US08722481B2 |
Superior integrity of high-k metal gate stacks by preserving a resist material above end caps of gate electrode structures
When forming high-k metal gate electrode structures in a semiconductor device on the basis of a basic transistor design, undue exposure of sensitive materials at end portions of the gate electrode structures of N-channel transistors may be avoided, for instance, prior to and upon incorporating a strain-inducing semiconductor material into the active region of P-channel transistors, thereby contributing to superior production yield for predefined transistor characteristics and performance. |
US08722471B2 |
Method for forming a via contacting several levels of semiconductor layers
A method for forming a via connecting a first upper level layer to a second lower level layer, both layers being surrounded with an insulating material, the method including the steps of: a) forming an opening to reach an edge of the first layer, the opening laterally continuing beyond said edge; b) forming a layer of a protection material on said edge only; c) deepening said opening by selectively etching the insulating material to reach the second lower level layer; and d) filling the opening with at least one conductive contact material. |
US08722470B2 |
CMOS with channel p-FinFET and channel n-FinFET having different crystalline orientations and parallel fins
An integrated circuit fabrication apparatus is configured to fabricate an integrated circuit with at least one p-FinFET device and at least one n-FinFET device. A bonding control processor is configured to bond a first silicon layer having a first crystalline orientation to a second silicon layer having a second crystalline orientation that is different from the first crystalline orientation. A material growth processor is configured to form a volume of material extending through the first silicon layer from the second layer up to the surface of first layer. The material has a crystalline orientation that substantially matches the crystalline orientation of second layer. An etching processor is configured to selectively etch areas of the surface of the first layer that are outside of the region to create a first plurality of fins and areas inside the region to create a second plurality of fins. |
US08722469B2 |
Memory cell and process for manufacturing the same
A memory cell and a process for manufacturing the same are provided. In the process, a first electrode layer is formed on a conductive layer over a substrate, and then a transition metal layer is formed on the first electrode layer. After that, the transition metal layer is subjected to a plasma oxidation step to form a transition metal oxide layer as a precursor of a data storage layer, and a second electrode layer is formed on the transition metal oxide layer. A memory cell is formed after the second electrode layer, the transition metal oxide layer and the first electrode layer are patterned into a second electrode, a data storage layer and a first electrode, respectively. |
US08722468B2 |
Semiconductor encapsulation method
A semiconductor encapsulation comprises a lead frame further comprising a chip carrier and a plurality of pins in adjacent to the chip carrier. A plurality of grooves opened from an upper surface of the chip carrier partially dividing the chip carrier into a plurality of chip mounting areas. A bottom portion of the grooves is removed for completely isolate each chip mounting area, wherein a width of the bottom portion of the grooves removed is smaller than a width of the grooves. In one embodiment, a groove is located between the chip carrier and the pins with a bottom portion of the groove removed for isolate the pins from the chip carrier, wherein a width of the bottom of the grooves removed is smaller than a width of the grooves. |
US08722466B2 |
Semiconductor packaging and fabrication method using connecting plate for internal connection
A semiconductor package with connecting plate for internal connection comprise: a plurality of chips each having a plurality of contact areas on a top surface; one or more connecting plates having a plurality of electrically isolated connecting plate portions each connecting a contact area of the semiconductor chips. The method of making the semiconductor package includes the steps of connecting one or more connecting plates to a plurality of semiconductor chips, applying a molding material to encapsulate the chips and the connecting plates, separating a plurality of connecting plate portions of the connecting plates by shallow cutting through or by grinding. |
US08722464B2 |
Method and system for template assisted wafer bonding
A method of fabricating a composite semiconductor structure includes providing a substrate including a plurality of devices and providing a compound semiconductor substrate including a plurality of photonic devices. The method also includes dicing the compound semiconductor substrate to provide a plurality of photonic dies. Each die includes one or more of the plurality of photonics devices. The method further includes providing an assembly substrate, mounting the plurality of photonic dies on predetermined portions of the assembly substrate, aligning the substrate and the assembly substrate, joining the substrate and the assembly substrate to form a composite substrate structure, and removing at least a portion of the assembly substrate from the composite substrate structure. |
US08722461B2 |
Leadframe based multi terminal IC package
A semiconductor package comprises a die attach pad and a support member at least partially circumscribing it. Several sets of contact pads are attached to the support member. The support member is able to be etched away thereby electrically isolating the contact pads. A method for making a leadframe and subsequently a semiconductor package comprises partially etching desired features into a copper substrate, and then through etching the substrate to form the support member and several sets of contact pads. Die attach, wirebonding and molding follow. The support member is etched away, electrically isolating the contact pads and leaving a groove in the bottom of the package. The groove is able to be filled with epoxy or mold compound. |
US08722460B2 |
Method and apparatus for fabricating integrated circuit device using self-organizing function
In a method of fabricating an integrated circuit device having a three-dimensional stacked structured, the step of fixing many chip-shaped semiconductor circuits to a support substrate or a circuit layer with a predetermined layout can be performed easily and efficiently with a desired accuracy. Temporary adhesion portions 12b of semiconductor chips 13 are temporarily adhered to corresponding temporary adhesion regions 72a of a carrier substrate 73a by way of sticky material. The carrier substrate 73a is then pressed toward a support substrate or a desired circuit layer, thereby contacting connecting portions 12 of the chips 13 on the carrier substrate 73a with corresponding predetermined positions on the support substrate or a circuit layer. Thereafter, by fixing the connecting portions 12 to the predetermined positions, the chips 13 are attached to the support substrate or the circuit layer with a desired layout. |
US08722458B2 |
Optical systems fabricated by printing-based assembly
Provided are optical devices and systems fabricated, at least in part, via printing-based assembly and integration of device components. In specific embodiments the present invention provides light emitting systems, light collecting systems, light sensing systems and photovoltaic systems comprising printable semiconductor elements, including large area, high performance macroelectronic devices. Optical systems of the present invention comprise semiconductor elements assembled, organized and/or integrated with other device components via printing techniques that exhibit performance characteristics and functionality comparable to single crystalline semiconductor based devices fabricated using conventional high temperature processing methods. Optical systems of the present invention have device geometries and configurations, such as form factors, component densities, and component positions, accessed by printing that provide a range of useful device functionalities. Optical systems of the present invention include devices and device arrays exhibiting a range of useful physical and mechanical properties including flexibility, shapeability, conformability and stretchablity. |
US08722455B2 |
Phase change memory structure having low-K dielectric heat-insulating material and fabrication method thereof
The present invention discloses a phase change memory structure having low-k dielectric heat-insulating material and fabrication method thereof, wherein the phase change memory cell comprises diode, heating electrode, reversible phase change resistor, top electrode and etc; the heating electrode and reversible phase change resistor are surrounded by low-k dielectric heat-insulating layer; an anti-diffusion dielectric layer is designed between the reversible phase change resistor and the low-k dielectric heat-insulating layer surrounding thereof. The present invention utilizes low-k dielectric material as heat-insulating material, thereby avoiding thermal crosstalk and mutual influence during operation between phase change memory cells, enhancing the reliability of devices, and eliminating the influence of temperature, pressure and etc. on phase change random access memory (PCRAM) data retention during the change from amorphous to polycrystalline states. Furthermore, an anti-diffusion dielectric layer is prepared between the low-k dielectric material and the phase change material, which can be used to prevent the elements of the phase change material from diffusing to low-k dielectric material. The fabrication process of said phase change memory is compatible with standard complementary metal-oxide semiconductor (CMOS) process and the chemical mechanical polishing (CMP) process with low pressure and light corrosion is adopted in polishing. |
US08722453B2 |
Photovoltaic device and method for manufacturing the same
The method includes: steps of forming an n-type diffusion layer having an n-type impurity diffused thereon at a first surface side of a p-type silicon substrate; forming a reflection prevention film on the n-type diffusion layer; forming a back-surface passivation film made of an SiONH film on a second surface of the silicon substrate; forming a paste material containing silver in a front-surface electrode shape on the reflection prevention film; forming a front surface electrode that is contacted to the n-type diffusion layer by sintering the silicon substrate; forming a paste material containing a metal in a back-surface electrode shape on the back-surface passivation film; and forming a back surface electrode by melting a metal in the paste material by irradiating laser light onto a forming position of the back surface electrode and by solidifying the molten metal. |
US08722451B2 |
Solid state energy photovoltaic device
A solid state energy conversion device and method of making is disclosed for converting energy between electromagnetic and electrical energy. The solid state energy conversion device comprises a wide bandgap semiconductor material having a first doped region. A thermal energy beam is directed onto the first doped region of the wide bandgap semiconductor material in the presence of a doping gas for converting a portion of the first doped region into a second doped region in the wide bandgap semiconductor material. A first and a second Ohmic contact are applied to the first and the second doped regions of the wide bandgap semiconductor material. In one embodiment, the solid state energy conversion device operates as a light emitting device to produce electromagnetic radiation upon the application of electrical power to the first and second Ohmic contacts. In another embodiment, the solid state energy conversion device operates as a photovoltaic device to produce electrical power between the first and second Ohmic contacts upon the application of electromagnetic radiation. |
US08722448B2 |
Method for fabricating photo detector
A photo detector and related fabricating method are disclosed. The photo detector includes a substrate, a first patterned semiconductor layer, a dielectric layer, a patterned conductive layer, an inter-layer dielectric, a second patterned semiconductor layer, two first electrodes disposed on the inter-layer dielectric and two second electrodes disposed on portions of the second semiconductor layer. The first patterned semiconductor layer having a first doping region and a second doping region is disposed on a transistor region. The dielectric layer is disposed to cover the substrate and the first semiconductor layer. The patterned conductive layer is disposed on the dielectric layer. The inter-layer dielectric having at least two openings adapted to expose the first doping region and the second doping region is disposed to cover the dielectric layer. The second patterned semiconductor layer is disposed on a photosensitive region. The first electrodes are electrically connected to the first patterned semiconductor layer. |
US08722447B2 |
Selenization of precursor layer containing CulnS2 nanoparticles
A method of fabrication of thin films for photovoltaic or electronic applications is provided. The method includes fabricating a nanocrystal precursor layer and selenizing the nanocrystal precursor layer in a selenium containing atmosphere. The nanocrystal precursor layer includes one of CuInS2, CuIn(Sy,Se1-y)2, CuGaS2, CuGa(Sy, Se1-y)2, Cu(InxGa1-x)S2, and Cu(InxGa1-x)(Sy, Se1-y)2 nanoparticles and combinations thereof, wherein 0≦x≦1 and 0≦y≦1. |
US08722445B2 |
Planar cavity MEMS and related structures, methods of manufacture and design structures
A method of forming at least one Micro-Electro-Mechanical System (MEMS) includes forming a plurality of discrete wires on a substrate. The method further includes forming a sacrificial cavity layer on the discrete wires. The method further includes forming trenches in an upper surface of the sacrificial cavity layer. The method further includes filling the trenches with dielectric material. The method further includes depositing metal on the sacrificial cavity layer and on the dielectric material to form a beam with at least one dielectric bumper extending from a bottom surface thereof. |
US08722443B2 |
Inductor structures for integrated circuit devices
An IC device (100) includes an IC body (106) having a base layer (108) and first and second upper layers (114, 116) on the base layer. The IC body includes a cavity region (104) extending through said base and first upper layers and at least a portion of said second upper layer. In the IC device, a portion of said second upper layer in the cavity region comprises a planar inductive element (102) having first and second contacting ends (140, 142). In the IC device, at least one support member (128, 130, 132) extends at least partially into said cavity region from said IC body in at least a first direction parallel to said base layer and intersects at least a portion of said planar inductive element. |
US08722442B2 |
Nitrogen-doped transparent graphene film and manufacturing method thereof
Provided is a transparent graphene film which is prepared by maintaining the primary reduced state of a graphene oxide thin film via chemical reduction, reducing the graphene oxide thin film with chemical vapor deposition, and doping nitrogen, thereby enhancing the conductivity and enabling the control of work function and a manufacturing method thereof. According to the present disclosure, a flexible, transparent, electrical conductivity-enhanced, and work function controllable graphene film can be large area processed and produced in large quantities so that can be applied in real industrial processes by forming a graphene oxide thin film on a substrate, performing the primary chemical reduction using a reducing agent, and performing further the secondary thermal reduction and nitrogen doping by injecting hydrogen and ammonia gas through chemical vapor deposition equipment. |
US08722441B2 |
Manufacturing process for solid state lighting device on a conductive substrate
A method for fabricating a light emitting device includes forming a trench in a first surface on first side of a substrate. The trench comprises a first sloped surface not parallel to the first surface, wherein the substrate has a second surface opposite to the first surface of the substrate. The method also includes forming alight emission layer over the first trench surface, but not over the remainder of the first substrate surface, and removing at least a portion of the substrate from the second side of the substrate to expose the light emission layer and allow it to emit light out of the protrusion or protrusions on the second side of the substrate. These protrusions may be elongated pyramids. |
US08722439B1 |
Engineered-phosphor LED packages and related methods
In accordance with certain embodiments, regions of spatially varying wavelength-conversion particle concentration are formed over light-emitting dies. |
US08722438B2 |
Method of manufacturing a display substrate
A method of manufacturing a display substrate is disclosed. In one embodiment, an electrode layer may be formed on a base substrate including a first cell area, a second cell area and an intervening area between the first and the second cell areas. First electrodes may be formed in display regions of the first and the second cell areas by patterning the electrode layer. The electrode layer in an intervening area may be removed. Source electrodes and drain electrodes of thin film transistor may be formed in the first and the second cell areas where the first electrodes are formed. |
US08722434B2 |
Integrated trench MOSFET with trench Schottky rectifier
An integrated circuit comprising trench MOSFET having trenched source-body contacts and trench Schottky rectifier having trenched anode contacts is disclosed. By employing the trenched contacts in trench MOSFET and trench Schottky rectifier, the integrated circuit is able to be shrunk to achieve low specific on-resistance for trench MOSFET, and low Vf and reverse leakage current for trench Schottky Rectifier. |
US08722432B2 |
Methods and system for on-chip decoder for array test
The present invention provides devices capable of testing the electrical performance of thin-film transistor backplane arrays and methods for their use. |
US08722428B2 |
Metal enhanced fluorescence from metallic nanoburger structures
The present invention provides for metallic nanostructures or nanoburgers comprising a dielectric layer positioned between metallic layers and their use in metal enhanced emissions systems to enhance emissions from fluorophores, including intrinsic and extrinsic; luminophores; bioluminescent species and/or chemiluminescent species. The multilayer nanoburgers exhibit several distinctive properties including significantly enhanced intensity of emissions, decreased lifetime and increased photostability by simply varying the thickness of the dielectric layer while maintaining a constant thickness of the two metallic layers on opposite sides of the dielectric layer. |
US08722425B2 |
Chromatography quantitative measuring apparatus
In a chromatography quantitative measuring apparatus according to the present invention, a beam applied from a light source to a chromatography test strip is formed into an elliptical shape by an optical means such as a cylindrical lens, a variation in absorbance that accompanies elution of a marker regent is detected while the elliptical beam is applied between a marker reagent hold part and a detection part, and a measurement is automatically started in a prescribed period of time since the detection of variation. According to the chromatography quantitative measuring apparatus so configured, non-uniform coloration is reduced by shaping the beam elliptically with the optical means, whereby the accuracy of quantitative analysis is enhanced, and the apparatus can be operated easily. |
US08722424B2 |
Chromatography quantitative measuring apparatus
In a chromatography quantitative measuring apparatus, a beam applied from a light source to a chromatography test strip is formed into an elliptical shape by an optical means such as a cylindrical lens, a variation in absorbance that accompanies elution of a marker regent is detected while the elliptical beam is applied between a marker reagent hold part and a detection part, and a measurement is automatically started in a prescribed period of time since the detection of variation. According to the chromatography quantitative measuring apparatus so configured, non-uniform coloration is reduced by shaping the beam elliptically with the optical means, whereby the accuracy of quantitative analysis is enhanced, and the apparatus can be operated easily. |
US08722421B2 |
Microfluidic device
A microfluidic device adapted such that the flow of fluids within the device is controlled by different surfaces of the device having different surface characteristics. Preferably the device comprises a substrate not formed from a hydrated oxide material. |
US08722420B2 |
Method for detecting an endogenous biomolecule
Provided is a method for the real-time visualization of an endogenous biomolecule to clarify the mechanisms of various diseases and enable diagnosis and treatment of these diseases. Specifically provided is a novel method for visualizing an endogenous biomolecule by using a magnetic resonance method (including Overhauser MRI and the electron spin resonance method). The aforesaid visualization method, whereby an endogenous biomolecule is visualized on a real-time basis, comprises: a step for treating a living organism to be examined by a magnetic resonance method and thus acquiring data of the endogenous biomolecule; a step for processing the data of the endogenous biomolecule thus obtained to give imaging data; and a step for displaying the imaging data thus obtained. |
US08722415B1 |
Method of detecting luminescent target ions with modified magnetic microspheres
This invention provides methods of using modified magnetic microspheres to extract target ions from a sample in order to detect their presence in a microfluidic environment. In one or more embodiments, the microspheres are modified with molecules on the surface that allow the target ions in the sample to form complexes with specific ligand molecules on the microsphere surface. In one or more embodiments, the microspheres are modified with molecules that sequester the target ions from the sample, but specific ligand molecules in solution subsequently re-extract the target ions from the microspheres into the solution, where the complexes form independent of the microsphere surface. Once the complexes form, they are exposed to an excitation wavelength light source suitable for exciting the target ion to emit a luminescent signal pattern. Detection of the luminescent signal pattern allows for determination of the presence of the target ions in the sample. |
US08722410B2 |
Methods for transferring molecular substances into plant cells
Provided are methods for introducing a molecule of interest into a plant cell comprising a cell wall. Methods are provided for genetically or otherwise modifying plants and for treating or preventing disease in plant cells comprising a cell wall. |
US08722409B2 |
Cofilin knockdown host cells and uses thereof
The present invention relates to a host cell comprising a cofilin-specific small interfering RNA (siRNA) sequence. The host cell may further comprise a nucleic acid encoding a recombinant protein. The present invention also relates to a method for producing a recombinant protein by the host cell comprising a cofilin-specific small interfering RNA (siRNA) sequence. |
US08722408B2 |
Trap vectors and gene trapping method by using the same
A trap vector containing a loxP sequence composed of inverted repeat sequence 1, a spacer sequence and inverted repeat sequence 2 in this order, the loxP sequence being a mutant loxP wherein a part of the inverted repeat sequence 1 or 2 is mutated. |
US08722404B2 |
Sheet for guiding regeneration of mesenchymal tissue and production method thereof
Method for regeneration of mesenchymal tissue from mesenchymal cells on a porous sheet composed of bioabsorbable polymer material. |
US08722403B2 |
Specimen preservation chamber and method
The present invention comprises a specimen preserver. A bubble reservoir is used to hold a preserving liquid such as artificial cerebrospinal liquid (aCSF). Oxygen is introduced into the aCSF by a gas diffuser which is attached to the bubble reservoir. The tissue samples are contained in one or more chambers in a holding platform. The platform is suspended well above the bottom of the bubble reservoir. The lower portion of each of the chambers is open toward the bottom of the bubble reservoir, but is covered by a fine mesh. The gas introduced into the aCSF circulates within the bubble reservoir. However, the tissue samples are not directly exposed to the gas bubbles because the fine mesh excludes the bubbles from the chambers in which the tissue samples are housed. |
US08722400B2 |
Artificial antigen presenting cells and uses therefor
The invention relates to novel artificial antigen presenting cells (aAPCs). The aAPC comprises at least one stimulatory ligand and at least one co-stimulatory ligand where the ligands each specifically bind with a cognate molecule on a T cell of interest, thereby mediating expansion of the T cell. The aAPC of the invention can further comprise additional molecules useful for expanding a T cell of interest. The aAPC of the invention can be used as an “off the shelf” APC that can be readily designed to expand a T cell of interest. Also, the aAPC of the invention can be used identify the stimulatory, co-stimulatory, and any other factors that mediate growth and expansion of a T cell of interest. Thus, the present invention provides powerful tools for development of novel therapeutics where activation and expansion of a T cell can provide a benefit. |
US08722398B2 |
Treatment of bone fracture
The use of mesenchymal stem cells cultured in the presence of HS-2 for the treatment of bone fracture. Repair of bone fracture using such cells is enhanced compared with the treatment of bone fracture using mesenchymal cells cultured without HS-2. These mesenchymal stem cells may be formulated in a pharmaceutical composition and injected directly into tissues surrounding the fracture or used in a biocompatible implant or prosthesis. |
US08722396B2 |
Bioreactor assembly for culture of photoautotrophic algae
A photobioreactor assembly, including a first generally horizontal manifold, a second generally horizontal manifold positioned below the first generally horizontal manifold, an array of generally parallel, generally transparent tubes extending between the manifolds, an air supply operationally connected to at least one manifold, a water filter, a water purifier, a water supply operationally connected to the water purifier, a pH sensor positioned to measure the pH in the array, and an electronic controller operationally connected to the pH sensor, the air supply, the water purifier, and the water supply. Each respective tube is connected in fluidic communication with the first horizontal manifold, and each respective tube is connected in fluidic communication with the second horizontal manifold. |
US08722395B2 |
Electronic analyte assaying device
The invention is an electronically processed single-step test device for detecting the presence of a preselected analyte in a fluid. The device includes a hollow rectangular outer casing, disposed within co-joined upper and lower sections of the casing are assay material, an electronic processing system, and a LCD display. The LCD display is observable through a viewing window. The assay material is a sorptive material including a fluid sample application region in the form of a sample wick in fluid communication with a test strip. The test strip includes an analyte capture region adjacent to a light shield. The electronic processing system includes red and green LEDs which are alternately pulsed or energized over predetermined periods of time to determine if fluid test results show a marker or markers in the capture region indicative of the presence of a preselected analyte in the fluid. If so, Yes+ is displayed on the LCD. If not, No− is displayed on the LCD. |
US08722394B2 |
Laboratory apparatus with an arrangement for the tempering of samples and method of tempering samples
The invention relates to a laboratory apparatus, in particular for performing a polymerase chain reaction (PCR) in a plurality of PCR-samples, which comprises an arrangement for tempering samples, the arrangement comprising a tempering block for the tempering of samples, the tempering block comprising a reception side, which provides receptacles for receiving sample vessels, and a contact side for the contact of at least one tempering device, at least one tempering device, arranged in an area of said contact side, a pressure device, which comprises a pressure element and an auxiliary element, said at least one tempering device being arranged between said auxiliary element and the tempering block, the pressure element being linked to said auxiliary element and to the tempering block, and being arranged to press said at least one tempering device against the tempering block by pressing said auxiliary element against said at least one tempering device, wherein at least one tempering device is shaped and arranged in said area to at least partially surround by itself said pressure element. |
US08722391B2 |
Process for CO2 capture using carbonates and biocatalysts with absorption of CO2 and desorption of ion-rich solution
A formulation and process for capturing CO2 use an absorption mixture containing water, biocatalysts and a carbonate compound. The process includes contacting a CO2-containing gas with the absorption mixture to enable dissolution and transformation of CO2 into bicarbonate and hydrogen ions, thereby producing a CO2-depleted gas and an ion-rich solution, followed by subjecting the ion-rich solution to desorption. The biocatalyst improves absorption of the mixture comprising carbonate compounds and the carbonate compound promotes release of the bicarbonate ions from the ion-rich solution during desorption, producing a CO2 gas stream and an ion-depleted solution. |
US08722385B2 |
Biological synthesis of difunctional hexanes and pentanes from carbohydrate feedstocks
Provided herein are methods for the production of difunctional alkanes in microorganisms. Also provided are enzymes and nucleic acids encoding such enzymes, associated with the difunctional alkane production from carbohydrates feedstocks in microorganisms. The invention also provides recombinant microorganisms and metabolic pathways for the production of difunctional alkanes. |
US08722383B2 |
PHA-producing bacteria
The present disclosure relates to isolated bacterial strains producing polyhydroxyalkanoate (PHA), microbial consortia including such strains, and cultures of such strains and microbial consortia. In particular, the present disclosure relates to compositions including such strains, microbial consortia, and cultures and methods of use thereof. |
US08722382B1 |
Xylanase having improved enzymatic activity
A xylanase having increased enzymaic activity is disclosed. The xylanase has a modified amino acid sequence of SEQ ID NO: 2, wherein Tryptophan at position 125 is substituted with Phenylalanine and Phenylalanine at position 163 is substituted with Tryptophan. |
US08722371B2 |
Cytochrome P450 oxygenases
Nucleic acids encoding cytochrome P450 variants are provided. The cytochrome P450 variants of have a higher alkane-oxidation capability, alkene-oxidation capability, and/or a higher organic-solvent resistance than the corresponding wild-type or parent cytochrome P450 enzyme. A preferred wild-type cytochrome P450 is cytochrome P450 BM-3. Preferred cytochrome P450 variants include those having an improved capability to hydroxylate alkanes and epoxidate alkenes comprising less than 8 carbons, and have amino acid substitutions corresponding to V78A, H236Q, and E252G of cytochrome P450 BM-3. Preferred cytochrome P450 variants also include those having an improved hydroxylation activity in solutions comprising co-solvents such as DMSO and THF, and have amino acid substitutions corresponding to T235A, R471A, E494K, and S1024E of cytochrome P450 BM-3. |
US08722367B2 |
Detecting PAX2 for the diagnosis of breast cancer
A method for monitoring breast conditions in a subject is disclosed. The method comprises determining a Paired Box 2 gene-to-beta defensin-1 gene (PAX2-to-DEFB1) expression ratio (the “Donald Predictive Factor” or “DPF”) in cells obtained from the breast of the subject, wherein the PAX2-to-DEFB1 expression ratio is correlated with breast conditions. Also disclosed is a kit for monitoring breast conditions and determining drug resistance. |
US08722363B2 |
Cytochrome P450S and uses thereof
The invention features isolated cytochrome P450 polypeptides and nucleic acid molecules, as well as expression vectors and transgenic plants containing these molecules. In addition, the invention features uses of such molecules in methods of increasing the level of resistance against a disease caused by a plant pathogen in a transgenic plant, in methods for producing altered compounds, for example, hydroxylated compounds, and in methods of producing isoprenoid compounds. |
US08722362B2 |
Monoclonal antibodies against HER2 antigens, and uses therefor
The present invention provides and includes monoclonal antibodies (mAbs) preferentially selective for HER2 antigens, hybridoma lines that secrete these HER2 antibodies or antibody fragments, and the use of such antibodies and antibody fragments to detect HER2 antigens, particularly those expressed by cancer cells. The present invention also includes antibodies that are specific for or show preferential binding to a soluble or secreted form of HER2. The present invention also includes an antibody or antibody fragment that is capable of reducing the activity of HER2 in at least one form, including a soluble form or a secreted form. The present invention further includes chimeric antibodies, processes for producing monoclonal and chimeric antibodies or monoclonal or chimeric antibodies, and their therapeutic uses, particularly in the detection of cancer most preferentially in human breast, stomach, and colon. The present invention further includes methods and kits for the immunodetection and immunotherapy of cells for samples which express HER2 antigens. |
US08722360B2 |
Method for producing a fermentation product using a genetically modified microorganism with a mutation to relieve carbon catabolite repression
The present invention is directed to novel genes mediating the carbon catabolite repression (CCR) of gluconeogenic genes. Furthermore, the polypeptides encoded by said genes as well as the use of said genes in a process for the production of a target fermentation product is provided. Processes for generating such microorganisms are also provided by the present invention. The invention is also related to a genetically engineered microorganism and its use for the production of a target fermentation product, wherein the gluconeogenic genes are relieved from CCR within said microorganism. |
US08722356B2 |
Sampling system and method
A sampling system and method may use a kit that has a package enclosing a swab and a receptacle. The swab may have a shaft and a tip. The tip may be substantially made of calcium alginate. The receptacle may contain a diluent, such as sodium citrate, and glass beads. The swab may be used in an environment to sample microorganisms present on surfaces or in equipment. The kit may be used in a method of sampling and the resulting sample may be used in a method of quantitative testing. |
US08722353B2 |
Analytical method for FAB and FAB′ molecules
A method of measuring acidic species generated by degradation of a Fab or Fab′ component of a Fab-PEG or a Fab′-PEG is provided. The method involves: a) cleaving PEG and a linker from the Fab-PEG or Fab′-PEG with an enzyme; b) optionally separating the PEG and linker from the Fab or Fab′ to provide isolated Fab or Fab′; and c) quantitatively analyzing acidic species associated with the cleaved Fab or Fab′ and/or the cleaved PEG. |
US08722351B2 |
Diagnostic tests for abnormal ovarian conditions
Methods and compositions, and a kit for diagnosing ovarian disorders including autoimmunity and ovarian cancer. Ovarian autoimmunity is associated with unexplained infertility or idiopathic premature ovarian failure that occurs in the absence of polyglandular disease. Methods and composition described herein are used to detect ovarian autoimmunity before the onset of ovarian dysfunction. Thus, those individuals are identified who would benefit from therapy to maintain, as well as restore, ovarian function. |
US08722341B2 |
Metapneumovirus strains and their use in vaccine formulations and sequences
Provided is an isolated mammalian negative strand RNA virus, metapneumovirus (MPV). Described are isolated mammalian negative strand RNA viruses identifiable as phylogenetically corresponding or relating to the genus Metapneumovirus and components thereof. Also described is mammalian MPV, subgroups and variants thereof, and genomic nucleotide sequences of different isolates of mammalian metapneumoviruses, in particular human metapneumoviruses. The use of the sequence information of different isolates of mammalian metapneumoviruses for diagnostic and therapeutic methods is provided. Nucleotide sequences encoding the genome of a metapneumovirus or a portion thereof, including both mammalian and avian metapneumovirus are described. Also provided are chimeric or recombinant viruses encoded by said nucleotide sequences and chimeric and recombinant mammalian MPV that comprise one or more non-native or heterologous sequences. |
US08722337B2 |
Integrated versatile kit for isolating components in biological samples
The instant invention provides an intergrated kit with solutions and instruments to isolate various biological samples from biological samples. The kit enables an user to preserve specimens and isolate biomolecules with features and benefits of high quality, easy, fast, no toxicity, safe to user and environment, low demanding, cost-effective, reducing waste, saving nature resources and protecting environment, and leads to a low-carbon and Green economy in preparation of specimens. The integrated kit enables the user to extract biomolecules including DNA/ccfDNA, Large RNA/mRNA/ccfRNA, Small RNA/miRNA/ccfmiRNA, Protein, Lipid, Carbohydrates, and Metabolite using one seamless procedure. |
US08722334B2 |
Analysis for nucleic acids by digital PCR
The present invention provides a method for analyzing nucleic acids for their lengths and relative abundance in a sample, based on digital amplification of individual template molecules. This invention has many applications, including those in noninvasive prenatal diagnosis, transplantation monitoring, and the detection and monitoring of cancers and virus-associated diseases. |
US08722332B2 |
Macrocyclic lactone resistance marker for dirofilaria immitis
The invention relates to a method for determining the responsiveness of a Dirofilaria spp. nematode to a macrocyclic lactone, by determining the genotype of the nematode at a position in a P-glycoprotein gene of the nematode corresponding to position 11, and optionally to position 618, in SEQ ID NO: 1, wherein the genotype GG at a position corresponding to position 11, or at positions corresponding to positions 11 and 618, in SEQ ID NO: 1 indicates that the nematode is likely resistant to the macrocyclic lactone. The invention also relates to methods for selecting a treatment to treat an animal infected with macrocyclic lactone resistant Dirofilaria spp nematode, and treating the animal; or for selecting a prophylactic to prevent an animal from becoming infected with a macrocyclic lactone resistant Dirofilaria spp nematode, and providing the prophylactic to the animal. The invention further relates to an isolated nucleic acid having at least 80% sequence identity to SEQ ID NO: 1. |
US08722325B2 |
Genetic changes in ATM and ATR/CHEK1 as prognostic indicators in cancer
The present invention relates to the discovery that, in human cancer, an 11q deletion of ATM together with an increase in ATR and CHEK1 expression correlates with resistance to ionizing radiation which could be overcome by inhibition of the ATR/CHEK1 pathway. It provides for methods of identifying patients unlikely to exhibit an adequate response to radiation therapy and/or chemotherapy who may benefit from ATR/CHEK1 pathway inhibition, as well as methods of treating said patients. |
US08722324B2 |
Methods for the detection of HIV-1-specific antibodies employing GP41 polypeptides
This invention relates to compositions and methods or the detection of human immunodeficiency virus-1 (HIV-1) infection by conducting an immunoassay comprising the steps of: (a) contacting a biological sample containing HIV-1 antibody with a peptide, having an epitope, of one or more of SEQ ID 49-56 to form a peptide-anti-HIV-1 antibody complex; (b) contacting the formed complex with an anti-HIV-1 antibody binding molecule to permit the anti-HIV-1 antibody binding molecule to bind to the anti-HIV-1 antibody of the formed peptide-anti-HIV-1 antibody complex and form an extended complex that is immobilized on a solid support; (c) removing unbound anti-HIV-1 antibody and anti-HIV-1 antibody binding molecule from the extended complex; and (d) determining the presence or concentration of the anti-HIV-1 antibody in the biological sample. |
US08722321B2 |
Patterning process
A negative pattern is formed by applying a resist composition onto a substrate, baking, exposing to high-energy radiation, baking (PEB), and developing the exposed resist film in an organic solvent developer to selectively dissolve the unexposed region of resist film. The resist composition comprising a hydrogenated ROMP polymer comprising recurring units having an acid labile group-protected carboxyl group and recurring units having a lactone structure displays a high dissolution contrast in organic solvent development, and exhibits high dry etch resistance even when the acid labile group is deprotected through exposure and PEB. |
US08722315B2 |
Optical disc and ultraviolet-curable composition for optical disc
An optical disc of the present invention includes at least a light reflection layer and a light transmission layer formed on a substrate, wherein recording and reading are performed by a laser beam through the light transmission layer, the light transmission layer is formed from a cured film of a ultraviolet-curable composition containing an epoxy acrylate resin obtained by reacting a half ester compound (A), which is obtained from a lactone-adduct of a hydroxyalkyl (meth)acrylate (a1) and a dibasic acid anhydride (a2), and an epoxy resin (B), and the film thickness of the light transmission layer is from 50 to 150 μm. |
US08722310B2 |
Lithographic printing plate precursor and method of preparing lithographic printing plate using the same
A lithographic printing plate precursor includes, in the following order: a support; an image-recording layer which is capable of forming an image by removing an unexposed area by an automatic development processor in the presence of a developer having pH of from 2 to 14 after exposure and contains (A) a sensitizing dye, (B) a polymerization initiator, (C) a polymerizable compound and (D) a polymer which is insoluble in water and alkali-soluble; and a protective layer, and the protective layer contains (E) a hydrophilic polymer which has a repeating unit represented by the formula (1) as defined herein and a repeating unit represented by the formula (2) as defined herein and a sum of the repeating unit represented by the formula (1) and the repeating unit represented by the formula (2) is at least 95% by mole based on total repeating units constituting the polymer. |
US08722308B2 |
Aluminum substrates and lithographic printing plate precursors
An aluminum-containing substrate can be provided for use in lithographic printing plate precursors. Before radiation-sensitive layers are applied, a grained and sulfuric acid anodized aluminum-containing support is treated with an alkaline or acidic pore-widening solution to provide its outer surface with columnar pores. The diameter of the columnar pores at their outermost surface is at least 90% of the average diameter of the columnar pores. Directly on this treated surface, a hydrophilic layer is applied, which hydrophilic layer contains a non-crosslinked hydrophilic polymer having carboxylic acid side chains. |
US08722305B2 |
Method of preparing carrier for electrophotography
A method of preparing a carrier for electrophotography, including a core material and a coating material layer formed on the surface of the core material, including: coating the core material with the coating material; and burning the coating material with a high-frequency induction heater, wherein the core material has a saturated magnetization of from 40 to 95 Am2/kg. |
US08722301B2 |
Transparent electrostatic charge image developing toner, electrostatic charge image developer, toner cartridge, process cartridge, image forming apparatus, and image forming method
A transparent electrostatic charge image developing toner satisfies the relationships of the following Formulas (1), (2), and (3) wherein Dt (μm) is a volume average particle diameter, upper GSDv is an upper volume particle size distribution index, and lower GSDp is a lower number particle size distribution index: 18≦Dt≦30; Formula (1): 1.05≦upper GSDv≦1.20; Formula (2): 1.29≦lower GSDp≦1.50 Formula (3). |
US08722300B2 |
Electrophotographic toner and method of preparing the same
Disclosed are an electrophotographic toner and a method of preparing the same. The electrophotographic toner includes latex; a colorant; and a releasing agent. The absolute value of a differential value of complex viscosity with respect to temperature, ( ⅆ η ⅆ T ) ⅆ ( log 10 η ) / ⅆ T of the electrophotographic toner in a temperature range of 100° C.-160° C. is in a range of about 0.03 to about 0.06, and complex viscosity (η) of the electrophotographic toner at 140° C. is in a range of about 1.0×102 Pa·s to about 6.0×102 Pa·s. |
US08722297B2 |
Resin binders for toners
The present invention relates to a resin binder for toners which contains a crystalline polyester which is produced by polycondensing at least an alcohol component containing an aliphatic diol having 2 to 12 carbon atoms and a carboxylic acid component containing an aliphatic dicarboxylic acid compound having 8 to 12 carbon atoms in an amount of from 70 to 100 mol %, wherein a content of a methyl ethyl ketone soluble component (at 20° C.) in the crystalline polyester is from 0.5 to 7% by weight on the basis of a weight of the crystalline polyester, and a difference between a melting point of the crystalline polyester and a peak top temperature observed in DSC measurement of the methyl ethyl ketone soluble component (“melting point of the crystalline polyester”−“peak top temperature observed in DSC measurement of the methyl ethyl ketone soluble component”) is within the range of from 1 to 15° C. |
US08722289B2 |
Electrophotographic photoreceptor and image-forming apparatus
It is to provide a sheet-shaped electrophotographic photoreceptor which has an uncoated area, is good in mechanical adhesiveness between the photosensitive layer and the sheet-shaped conductive substrate but excellent ease of peeling with a solvent, and is further good in electrical properties. The electrophotographic photoreceptor comprises a sheet-shaped conductive substrate and a photosensitive layer provided thereon, wherein the electrophotographic photoreceptor contains a photosensitive layer-uncoated area within the sheet surface, and the photosensitive layer contains a copolycarbonate resin having an extremely restricted specific structure. |
US08722287B2 |
Phase shift focus monitor reticle, manufacturing method thereof and method for monitoring focus difference
The invention provides a phase shift focus monitor reticle, a manufacturing method thereof, and a method of monitoring focus difference using the phase shift focus monitor reticle. The phase shift focus monitor reticle comprises a shield comprising a plurality of light-transmitting portions with a certain width; and a glass layer positioned on the shield layer comprising a plurality of openings at the light-transmitting portions; wherein the width of the openings is half of the width of the light-transmitting portions; the depth of the openings is n*λ/(N−1), wherein λ is the wavelength of the lights incident on the phase shift focus monitor reticle in air, N is the refractive index of the glass layer, n is a positive integer. The invention can be applied to thicker photoresist and different process machines. |
US08722285B2 |
Pellicle for lithography
A pellicle for lithography, in which an agglutinant layer is so controlled that the deformation of the pellicle frame is prevented from transferring to an exposure original plate to which the pellicle is attached so that pattern transferred scarcely undergoes deformation; in particular the agglutinant layer has a Young's modulus of 0.02 to 0.08 MPa and a tensile bond strength of 0.04 to 0.08 N/mm2. |
US08722281B2 |
Fuel cell, fuel cell module, and fuel cell device
There are provided a fuel cell capable of suppressing damage to an end thereof, and a fuel cell module and a fuel cell device that include the fuel cell. In a fuel cell (1) wherein a fuel electrode layer (3) is formed on one of opposite main surfaces of a solid electrolyte layer (4) and an air electrode layer (5) is formed on the other of the main surfaces, and electric power is generated by utilizing a fuel gas and an oxygen-containing gas, an oxidation suppression layer (10) is located closer to the fuel electrode layer (3) than at least the solid electrolyte layer (4) on one end of the fuel cell (1), the oxidation suppression layer (10) being composed mainly of silicate containing at least one of elements belonging to Group 2 on the periodic table. This makes it possible to provide a fuel cell (1a) capable of suppressing damage to and oxidation of one end thereof. |
US08722279B2 |
Polyazole-containing composition
Composition in the form of a solution and/or dispersion, comprising: at least one polyazole with an intrinsic viscosity, measured in at least 96% by weight sulfuric acid, in the range from 3.0 to 8.0 g/dl, and orthophosphoric acid (H3PO4) and/or polyphosphoric acid, wherein the polyazole content, based on the total weight of the composition, is in the range from 0.5% by weight to 30.0% by weight, the H3PO4 and/or polyphosphoric acid content, based on the total weight of the composition, is in the range from 30.0% by weight to 99.5% by weight, the H3PO4 and/or polyphosphoric acid concentration, calculated as P2O5 (by acidimetric means), based on the total amount of H3PO4 and/or polyphosphoric acid and/or water, is in the range from 70.5% to 75.45%. Additionally protected are particularly advantageous processes for preparation and for use of the inventive composition. |
US08722278B2 |
Solid oxide fuel cell and fuel cell module comprising the solid oxide fuel cell
Disclosed is a solid oxide fuel cell that has a high initial power generation performance and a good power generation durability. The fuel cell comprises at least a fuel electrode, an electrolyte, an air electrode, and a current collecting part disposed on the air electrode, wherein the current collecting part comprises an electroconductive metal and an oxide, the electroconductive metal is silver and palladium, the oxide is a perovskite oxide, and the content of the oxide is more than 0 (zero) and less than 0.111 in terms of weight ratio to the electroconductive metal. |
US08722275B2 |
Apparatus comprising assembly jig and method for stacking fuel cells
An apparatus for fuel cell stacking includes an assembly jig having a base; an alignment assembly configured to be engaged with the base; and a compression assembly configured to be engaged with the alignment assembly. |
US08722272B2 |
Modular fuel cell system module for connection to an aircraft fuselage
A fuel cell system module for use in an aircraft includes at least one fuel cell system component. The fuel cell system module is connectable modularly to a fuselage section of the aircraft. A housing element of the fuel cell system module is designed to form a section of an outer skin of the aircraft when the fuel cell system module is in the state connected to the fuselage section of the aircraft. |
US08722271B2 |
Flow field plate with relief ducts for fuel cell stack
Flow field plate constructions for bipolar plates are disclosed for use in fuel cell stacks that are subject to freezing temperatures. In designs having internal coolant flow fields and reactant backfeed ports, relief ducts are provided in the supporting walls surrounding the backfeed ports in order to allow for ice formation and thus prevent cracking of the plates. |
US08722268B2 |
Fuel cell system including an air pressure-driven ejector
A fuel cell system comprises a fuel cell stack, a cell voltage monitor, a hydrogen tank, a hydrogen supply channel, an ejector, a hydrogen off-gas channel, a purge valve, a compressor, an air supply channel, a pressure control unit for controlling air pressure, a pilot pressure input channel branching off from the air supply channel and inputting the air pressure to the ejector as pilot pressure, and a control unit for controlling the purge valve and the pressure control unit. The ejector includes a pressure control mechanism which increases the ejector's secondary-side pressure by increasing the area of the nozzle's ejecting hole when the pilot pressure input from the pilot pressure input channel rises. When electricity generation status of the fuel cell stack is judged to be poor, the control unit opens the purge valve after raising the air pressure and the pilot pressure by using the pressure control unit. |
US08722267B2 |
Fuel cell terminal plate, method for manufacturing the plate, and fuel cell incorporating the plate
A front terminal plate (31) that is joined to a fuel cell unit (40) at the front end of a fuel cell stack has a metal-plating layer (31b) formed on the side to be joined to the fuel cell unit (40). The metal-plating layer (31b) is formed so as to cover the surface of a plate (31a), and the surface of the metal-plating layer (31b) is flat. The thickness of the metal-plating layer (31b) in an electrode-facing region (31c) that faces an electrode region of the fuel cell unit (40) is different from the thickness of the metal-plating layer (31b) in a peripheral region (31d) that surrounds the electrode-facing region (31c), and the thickness of the metal-plating layer (31b) in the peripheral region (31d) is larger than the thickness of the metal-plating layer (31b) in the electrode-facing region (31c). |
US08722261B2 |
Recycler for direct methanol fuel cell and method of operating the same
A recycler for a direct methanol fuel cell (DMFC) that uses methanol as a direct feed fuel includes: a housing in which a gas-liquid mixture recovered from a stack is accommodated; a rotor rotatably mounted in the housing; and a motor to rotate the rotor, wherein, when the rotor is rotated by the motor, a phase separation occurs such that liquid in the gas-liquid mixture is collected mainly in an outer region of the housing and gas is collected in the center region of the housing due to the centrifugal force. Accordingly, as it is unnecessary to align a liquid outlet port of the housing with a gravitational direction, the recycler can be employed in a mobile apparatus whose orientation occasionally changes. Also, the recycler does not use a membrane whose performance is rapidly reduced over time so that effective performance can be maintained for a long operation time. |
US08722256B2 |
Multi-layered, chemically bonded lithium-ion and lithium/air batteries
Disclosed are multilayer, porous, thin-layered lithium-ion batteries that include an inorganic separator as a thin layer that is chemically bonded to surfaces of positive and negative electrode layers. Thus, in such disclosed lithium-ion batteries, the electrodes and separator are made to form non-discrete (i.e., integral) thin layers. Also disclosed are methods of fabricating integrally connected, thin, multilayer lithium batteries including lithium-ion and lithium/air batteries. |
US08722253B2 |
Electrode comprising protective layer for lithium ion secondary battery and lithium ion secondary battery
A lithium ion secondary battery containing a pair of electrodes facing each other, and a separator interposed between the electrodes, wherein at least one of the electrodes has a protecting layer, an active-material containing layer, and a collector sequentially from the separator. The protecting layer contains a silicone resin particle having at least one structural unit represented by RSiO1.5 and R2SiO, where R represents an alkyl group having 1 to 6 carbon atoms or a phenyl group. |
US08722249B2 |
Flooded lead-acid battery and method of making the same
Positive active material pastes for flooded deep discharge lead-acid batteries, methods of making the same and lead-acid batteries including the same are provided. The positive active material paste includes lead oxide, a sulfate additive, and an aqueous acid. The positive active material paste contains from about 0.1 to about 1.0 wt % of the sulfate additive. Batteries using such positive active material pastes exhibit greatly improved performance over batteries with conventional positive active material pastes. |
US08722248B2 |
Active element and battery as well as method for the production thereof
The present invention relates to an active element for a battery whose material contains copper oxyphosphate and an additive improving the conductivity. The proportion of the additive improving the conductivity in the material is between 3 and 7 wt. %, preferably between approximately 3 wt. % and approximately 5 wt. %, and the proportion of the copper oxyphosphate in the material adds up to 100 wt. %. The invention additionally relates to a battery having an active element of this type as well as a method for producing an active element of this type and a battery of this type. The battery according to the invention is suitable in particular for use in medical implants. |
US08722247B2 |
Clathrate allotropes for rechargeable batteries
The present disclosure is directed at clathrate (Type I) allotropes of silicon, germanium and tin. In method form, the present disclosure is directed at methods for forming clathrate allotropes of silicon, germanium or tin which methods lead to the formation of empty cage structures suitable for use as electrodes in rechargeable type batteries. |
US08722245B2 |
Anode for secondary battery, secondary battery, and method of manufacturing anode for secondary battery
An anode for secondary battery capable of improving cycle characteristics, a secondary battery using the anode, and a method of manufacturing an anode for secondary battery are provided. An anode active material layer is formed by vapor phase deposition method, and contains Si as an element. In the anode active material layer, there are a plurality of primary particles grown in the thickness direction. The primary particles aggregate and form a plurality of secondary particles. At least some of the primary particles have shape curved in the identical direction to an anode current collector on the cross section in the thickness direction. Thereby, stress due to expansion and shrinkage due to charge and discharge can be relaxed. |
US08722243B2 |
Material for use as electrolyte, lithium secondary battery electrolyte, lithium secondary battery employing the same, and novel lithium salt
An inventive electrolyte material contains a lithium salt comprising the following components (A1) and (B), or contains the following components (A1), (A2) and (B): (A1) a lithium cation; (A2) an organic cation; and (B) a cyanofluorophosphate anion represented by the following general formula (1): −P(CN)nF6-n (1) wherein n is an integer of 1 to 5. The inventive electrolyte material is excellent in electrochemical properties, i.e., has a higher electrical conductivity and a higher oxidation potential, and is capable of forming an electrode protection film, so that a highly safe lithium secondary battery can be provided. |
US08722240B2 |
Single cell and power battery pack comprising the same
A single cell and a power battery pack comprising the same are provided. The single cell comprises: a shell; a cover board sealing an open end of the shell; an electrode core disposed inside the shell; an electrode terminal extending through the cover board, the electrode terminal comprising a first end portion connected with the electrode core inside the shell, a second end portion protruding outside the shell, and a middle portion between the first end portion and the second end portion; and an insulating member disposed between the electrode terminal and the cover board for insulating the electrode terminal; wherein each of the first end portion and the second end portion comprises a plurality of flexible conductive members. |
US08722239B2 |
Terminal of rechargeable battery, method of assembling the terminal of rechargeable battery, rechargeable battery module and method of assembling the rechargeable battery module
A terminal of a rechargeable battery, the terminal including a current collecting terminal electrically coupled to an electrode assembly inside a case, wherein the current collecting terminal protrudes from the case; a terminal plate outside of the case and coupled to the current collecting terminal; and a plate spring on the terminal plate and coupled to the current collecting terminal. |
US08722238B2 |
Direct resistance welding—self brazing of aluminum to molybdenum pin
A direct welding process for joining a current collector to a terminal pin in the construction of electrochemical cells is described. The resistance welding process utilizes increased current combined with an applied force to bond dissimilar metals with a melting temperature differential of preferably more than 500° C. Preferably, the method is used to bond the terminal pin to the cathode current collector. This method of attachment is suitable for either primary or secondary cells, particularly those powering implantable biomedical devices. |
US08722235B2 |
Thin printable flexible electrochemical cell and method of making the same
A thin printed flexible electrochemical cell with a high moisture and oxygen barrier polymer film sealed and folded package featuring a printed cathode deposited on a highly conductive carbon printed cathode collector with a zinc foil anode or printed anode placed adjacent to the cathode. After the cell components are added to the special laminated polymer substrate, the web is processed automatically on a modified high-speed commercial horizontal pouch filling machine to complete the cell assembly process. In this process a starch coated paper separator layer may be inserted over the anode and the cathode, and then the aqueous electrolyte solution is added to the cell. To complete the process, all four edges of the cell are heat sealed to confine the cell components within the cell cavity and each cell is trimmed off the continuous web. |
US08722221B2 |
Method of discharging a nickel-metal hydride battery
A method for discharging a nickel-metal hydride storage battery comprising a positive electrode containing nickel hydroxide, a negative electrode containing a hydrogen absorbing alloy, an alkaline electrolyte, and an alkali conducting separator provided between the positive electrode and the negative electrode. The alkali conducting separator may be a solid alkali metal ion super ion conducting material, wherein the alkali metal is Na, K, or Li. |
US08722219B2 |
Fuel cell stack having gas discharge passage and drainage passage joined at one end of the stack
A fuel cell stack includes stacked unit fuel cells provided between end holding members, each unit fuel cell having a membrane electrode assembly including an anode and a cathode. A pair of separators respectively contact the anode and the cathode, and respectively form reaction gas passages between one separator and the anode, and between the other separator and the cathode. For each reaction gas passage, a gas supply passage and a gas discharge passage are formed through the unit fuel cells and one end holding member so that they communicate with the reaction gas passage of each unit fuel cell, and a drainage passage is also formed through the unit fuel cells and one end holding member. An end of the drainage passage and an end of the gas discharge passage on the side of the other end holding member are joined to each other. |
US08722218B2 |
Diagnostic to determine a valve/line freeze-up or failure in a fuel cell bleed manifold unit
A system and method for determining whether valves in a fuel cell system bleed manifold unit (BMU) are blocked with ice or have otherwise failed. The system opens a first bleed valve, closes a second bleed valve and opens an exhaust valve, and then reads a pressure signal to determine whether there is flow through a flow restriction to determine whether the first bleed valve or the exhaust valve is blocked. The system then closes the exhaust valve, leaves the first bleed valve open, and again reads the pressure signal to determine the pressure drop across the flow restriction, which will indicate whether the flow restriction the pressure sensor lines are blocked. The system then closes the first bleed valve and opens the second bleed valve to determine whether the pressure signal indicates a flow through the second bleed valve. |
US08722213B2 |
Lubricant with non-terminal functional groups
Lubricant with non-terminal functional groups. The location of the functional groups minimizes free chain length and molecular weight of a lubricant while simultaneously maximizing evaporation temperature. The locations of the functional groups to the backbone of the molecule of the lubricant allows for shorter lengths of free backbone length between functional groups attached to a lubricated surface. The lubricant lubricates mechanical devices including hard disk drives. The lubricant can also be added to media or other mechanical parts in conjunction with other lubricants. |
US08722211B2 |
Magnetic memory devices and methods of manufacturing such magnetic memory devices
A magnetic memory device may include a first ferromagnetic layer, a second ferromagnetic layer, and a tunnel barrier layer arranged on a substrate. The tunnel barrier layer may include a crystal structure and may be arranged between the first ferromagnetic layer and the second ferromagnetic layer. At least the first ferromagnetic layer may include a first layer in contact with the tunnel barrier layer and a second layer in contact with the first layer, and an orientation of the first layer with respect to the tunnel barrier layer may be greater than an orientation of the second layer with respect to the tunnel barrier layer. |
US08722209B2 |
Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element
The invention relates to a compound having a pyridoindole ring structure having a substituted pyridyl group of formula (1); and to an organic electroluminescent device comprising a pair of electrodes and at least one organic layer interposed between the electrodes, wherein at least one of the organic layer(s) contains the compound: wherein Ar represents a substituted or unsubstituted aromatic hydrocarbon group, a substituted or unsubstituted aromatic heterocyclic group, or a substituted or unsubstituted condensed polycyclic aromatic group; R1 to R10 may be the same or different from one another and each independently represents a hydrogen atom, a fluorine atom, a cyano group, an alkyl group, or a substituted or unsubstituted aromatic hydrocarbon group; Z represents a 6-membered aromatic heterocyclic ring containing one nitrogen atom; and m and n each independently represents an integer of 1 to 3, provided that n is 1 when m is 2 or 3. |
US08722208B2 |
Organic electroluminescent device
Disclosed is an organic electroluminescent device (organic EL device) which is improved in luminous efficiency, fully secured of high driving stability, and of a simple structure. The organic EL device is constituted of an anode, organic layers containing a phosphorescent light-emitting layer, and a cathode piled one upon another on a substrate and a phosphine oxide derivative represented by general formula (1) is contained in a phosphorescent light-emitting layer, an electron-transporting layer, a hole-blocking layer, or an exciton-blocking layer. In general formula (1), L1 is a direct bond or an aromatic group with a valence of 1-3 and Ar1 is an aromatic group. The two Ar1 groups linked to the same nitrogen atom may form a nitrogen heterocycle and may further form a fused ring together with the said nitrogen heterocycle. |
US08722204B2 |
Aluminum coated Steel sheet having excellent oxidation resistance and heat resistance
Provided is an aluminum coated steel sheet having excellent oxidation and heat resistance. The aluminum coated steel sheet includes an aluminum coating layer and an alloy layer. The aluminum coating layer is formed on a surface of a steel sheet which includes 0.001 to 0.015 wt % of carbon (C), 0.05 to 0.3 wt % of silicon (Si), 0.1 to 0.6 wt % of manganese (Mn), 0.01 to 0.05 wt % niobium (Nb), 0.01 wt % or less of phosphorus (P), 0.01 wt % or less of sulfur (S), 0.1 wt % or less of soluble aluminum (Al), 0.05 to 0.5 wt % of copper (Cu), 0.05 to 0.5 wt % nickel (Ni), 0.001 to 0.01 wt % of nitrogen (N), and the balance of Fe and inevitable impurities. The alloy layer includes an intermetallic compound at an interface between the steel sheet and the aluminum coating layer. |
US08722199B2 |
Electrodeposited copper foil, its manufacturing method, surface-treated electrodeposited copper foil using the electrodeposited copper foil, and copper-clad laminate and printed wiring board using the surface-treated electrodeposited copper foil
It is an object of the present invention to provide an electrodeposited copper foil which has a lower profile and a higher gloss than low-profile electrodeposited copper foil conventionally supplied in markets. For achieving this object, the present invention employs an electrodeposited copper foil which has a super low profile, the surface roughness (Rzjis) of the deposit side of lower than 1.0-micron meter, and the gloss [Gs(60-deg.)] thereof of not lower than 400 irrespective to its thickness. The present invention also provides a manufacturing method of an electrodeposited copper foil obtained by electrodeposition using a sulfuric acid base copper electrolytic solution obtained by adding 3-mercapto-1-propanesulfonic acid and/or bis(3-sulfopropyl)disulfide, a quaternary ammonium salt polymer having a cyclic structure, and chlorine. |
US08722198B2 |
Method of preserving wood by injecting particulate wood preservative slurry
The present invention is directed to wood preservative compositions, methods of treating wood, and wood that has been treated with the preservative, which includes injectable particles comprising one or more sparingly soluble copper salts. The copper-based particles are sufficiently insoluble so as to not be easily removed by leaching but are sufficiently soluble to exhibit toxicity to primary organisms primarily responsible for the decay of the wood. Exemplary particles contain for example copper hydroxide, basic copper carbonate, copper carbonate, basic copper sulfates including particularly tribasic copper sulfate, basic copper nitrates, copper oxychlorides, copper borates, basic copper borates, and mixtures thereof. The particles typically have a size distribution in which at least 50% of particles have a diameter smaller than 0.25 μm, 0.2 μm, or 0.15 μm. At least about 20% and even more than 75% of the weight of the particles may be composed of the substantially crystalline copper salt. Wood or a wood product may be impregnated with copper-based particles of the invention. |
US08722197B2 |
Sliding mating part in lubricated regime, coated by a thin film
A thin layer is deposited on a surface having a roughness profile whereof the parameters and mean period are determined for improving the tribological performance, so that the ratio A between the square of the mean period of the profile (PSM) in μm and the roughness profile (Pa) in μm, as defined by French standard ISO 4288, is equal to or greater than 5×105 μm. |
US08722193B2 |
Gas barrier laminate and a method of producing the same
To provide a gas barrier laminate having a gas barrier layer obtained by crosslinking the carboxyl groups of a polycarboxylic acid-type polymer with polyvalent metal ions maintaining good productivity, the crosslinking being accelerated with polyvalent metal ions to exhibit more excellent gas barrier property. A gas barrier laminate comprising a layer (A) of a non-aqueous resin containing a metal element in the polymer skeleton thereof, and a layer (B) of a polycarboxylic acid-type polymer in which an ionic crosslinking is formed with a polyvalent metal among the carboxyl groups. |
US08722187B2 |
Solventless process for the preparation of amine functional polyetherimide resins with improved melt flow
The disclosure relates to a process that includes blending a polyimide resin and a primary alky amine organic compound to produce an aryl amine functionalized polyimide, having aryl amine functionality in excess of any anhydride functionality. The polyimide resin can have a weight average molecular weight (Mw) from 5,000 to 100,000 daltons. The organic compound can include at least one primary aliphatic amine without a direct linkage of a nitrogen to an aryl group and without a functionality selected from a halogen functionality, a hydroxyl functionality, a sulfonic acid functionality, a sulfonic acid salt functionality, and combinations thereof. The disclosure also relates to alkyl imide functionalized polyimides also with aryl amine functionalized polyimides, having aryl amine functionality in excess of any anhydride functionality and articles produced therefrom. |
US08722182B2 |
Polarizing plate, optical film and image display
A polarizing plate of the present invention comprises a polarizer; an adhesive layer; and a transparent protective film bonded to at least one side of the polarizer with the adhesive layer interposed therebetween, wherein the adhesive layer is formed from an active energy ray curing adhesive containing at least one curable component, and the adhesive layer has a glass transition temperature (Tg) of 60° C. or more, and a thickness of 0.01 μm an to 5 μm. The polarizing plate has sufficient durability in a severe environment at high temperature and high humidity. |
US08722181B2 |
Resin composition and multilayer structure using the same
The present invention provides a resin composition of a saponified ethylene-vinyl ester copolymer can provide a molded product including layer of the resin composition with less thickness variation and excellent gas-barrier properties, even if the layer is subjected to stretch forming such as deep drawing forming and vacuum-pressure forming where the layer is applied with different tension from side to side thereof in short time. The resin composition comprises an EVOH resin having ethylene content of 20 to 60 mol % and a PVA having 1,2-diol structural unit in a side chain. The present invention also provides a multilayer structure using the resin composition. |
US08722172B2 |
Honeycomb structure, manufacturing method thereof, and catalyst carrying honeycomb structure
There is disclosed a honeycomb structure onto which a large amount of catalyst can be carried while suppressing an increase in pressure drop. In a honeycomb structure comprising porous partition walls by which a plurality of cells that become through channels of a fluid are partitioned and in which a plurality of pores are formed. In each of the partition walls, pores having pore diameters larger than a thickness of the partition wall in a section thereof which is perpendicular to an extending direction of the cells are formed so as to occupy 4 to 11% of the total volume of the pores formed in the partition walls. |
US08722167B2 |
Image recording media, methods of making image recording media, imaging layers, and methods of making imaging layers
Imaging layers, optical disks, and methods of preparation of each, are disclosed. |
US08722166B2 |
Emergency extrication tape
Presented herein is a safety device for use by first responders and search and rescue teams (e.g., rescue personnel). In one arrangement, the device allows for safely extricating occupants from vehicle wreckage. In one arrangement, the safety device may be adhered to glass to permit breaking and removal of such glass without harming the occupants of the vehicle. In another arrangement, the safety device may be utilized to adhere over and cover sharp edges, which may cause injury to rescue personnel and/or victims during removal from a vehicle or other wreckage. |
US08722163B2 |
Recyclable colorants in plastic beverage containers
A thermoplastic article includes one or more recyclable-friendly synthetic coloring pigments. The pigment has a melting temperature that is about 20 to about 50° C. higher than that of the base polymer. This enables the pigment to remain predominately intact (e.g., unmelted) during injection molding and act as a colorant in the preform and resulting blow molded container. When the container is remelted during subsequent processing, such as post-consumer recycling, the pigment melts and transesterifies into the base polymer. Thus, upon such further processing, the pigment effectively is subsumed into the base polymer and does not affect the basic characteristics and properties of the base polymer. |
US08722159B2 |
Recording medium
A recording medium includes an ink-receiving layer on a substrate, in which the ink-receiving layer contains hydrated alumina, a C1-4 alkylsulfonic acid, and a salt of a compound of general formula (1): X1—R1—(S)n—R2—X2, wherein n represents 1 or 2; X1 and X2 each independently represent H, NH2, or COOH, and at least one of X1 and X2 represents NH2 or COOH; R1 and R2 each independently represent alkylene, arylene, or heteroarylene, and they may be bonded to each other to form a ring, upon letting the proportion of the C1-4 alkylsulfonic acid be A percent by mass with respect to hydrated alumina, A is in the range of 1.0 to 2.0, and upon letting the proportion of the salt of the compound of general formula (1) be B percent by mass with respect to hydrated alumina, B is in the range of 0.5 to 5.0. |
US08722153B2 |
Release coating composition and method of forming the same
A release coating composition includes a curable polysiloxane and an aerosol suppressant that has more than one SiO4/2 unit. The aerosol suppressant includes the polymerization product of a siloxane and a cyclic polysiloxane polymerized in the presence of a polymerization catalyst. The siloxane has units of the chemical formula (SiO4/2)(RaRb2SiO1/2)x wherein Ra is a vinyl moiety, Rb is an alkyl moiety, and x is a number from 1.05 to 4. The release coating composition is formed by combining the aerosol suppressant and a curable polysiloxane. The release coating composition is also used to coat a substrate in a release coating process producing a mist of less than 50 mg/cubic meter measured at approximately 457 m/min. |
US08722151B1 |
Automated method for making a component with a wood grained appearance
A method for creating a wood like appearance on a synthetic component using a sales client device, a network, computer instructions for creating a work order, a tray with scannable tray identifier to hold a synthetic component, a production client device connected to the network with computer instructions for applying a base coat, a glaze, and a top coat with spray treatment devices to the synthetic component as it automatically moves on a conveyer system a portion of which is connected to the production client device. Scanning a scannable tray identifier with a plurality of sensors to link the tray identifier to the work order and to authenticate and validate the location of the tray on the conveyor system, or to initiate an alerting device. The method uses temperature control environments to simultaneously control humidity and heating of the synthetic component while spraying, drying and UV curing. |
US08722150B2 |
Process for the production of a dark-color multi-layer coating
A process for the production of a dark-color multi-layer coating, comprising the successive steps:(1) applying an NIR-opaque coating layer A′ from a waterborne pigmented coating composition A to a substrate,(2) applying a coating layer B′ from a waterborne pigmented coating composition B onto the substrate provided with coating layer A′,(3) subjecting the coated substrate obtained in step (2) to a drying step,(4) applying a clear coat layer, and(5) curing the coating layers simultaneously;wherein both coating compositions A and B comprise aqueous microgel and sheet silicate,wherein the pigment content of coating composition A consists 90 to 100 wt. % of aluminum flake pigment and 0 to 10 wt. % of further pigment,wherein the pigment content of coating composition B consists 50 to 100 wt. % of black pigment with low NIR absorption and 0 to 50 wt. % of further pigment. |
US08722149B2 |
Opaque wet, see-through weather-resistive barriers and methods for making
The present invention provides aqueous self-inspecting wet coatings or films that dry to form translucent to clear weather-resistive barriers on a substrate, preferably a building substrate such as sheathing. The coatings comprise, as a wet film, one or more aqueous emulsion or dispersion polymer that can form a film in use conditions and less than 6% pigment volume concentration (% PVC), of one or more opacifier, one or more extender in amounts up to critical % pigment volume concentration (CPVC), optionally, one or more pigment, and substantially no void, hollow core, or hollow sphere containing pigment. The coatings or films enable one to apply the correct amount of coating to make a weather barrier that dries to a see-through coating or film. |
US08722146B2 |
Method for making liquid separation membrane
A method for making a liquid separation membrane, including: (1) providing a polyvinylidene fluoride liquid separation membrane or polypropylene liquid separation membrane prepared by a thermally induced phase separation method as a substrate membrane, soaking the substrate membrane with water or a weak polar organic liquid to make membrane pores of the substrate membrane filled with the liquid, the soaking time being between 0.5 s and 1 min, and the weak polar organic liquid being indissolvable and compatible with the polyvinylidene fluoride liquid separation membrane or polypropylene liquid separation membrane; (2) coating a casting solution of polyvinylidene fluoride on the surface of the soaked substrate membrane obtained in step (1), and quickly soaking the substrate membrane in a coagulating bath heated to a temperature of 60-100° C. for curing to yield the liquid separation membrane. |
US08722142B2 |
Light induced electroless plating
A method and composition for plating metal contacts on photovoltaic solar cells is described. The cell is immersed in an aqueous bath containing platable metal ions and a chemical reducing agent. The cell is then exposed to light, causing the two sides of the cell to become oppositely charged. The metal ions are plated without requiring an external electrical contact, without backside anodic corrosion and without the need for backside sacrificial material. |
US08722141B2 |
Process for the continuous production of polycrystalline high-purity silicon granules
High-purity polysilicon granules are prepared by depositing reaction gas on silicon granules in a fluidized bed reactor having: a reactor space comprising at least two zones lying one above the other, the lower zone weakly fluidized by introduction of a silicon-free gas into silicon granules in the lower zone by a plurality of individual dilution gas nozzles, and a second, reaction zone directly abutting the lower zone, the reaction zone heated via its outwardly bounding wall, introducing silicon-containing reaction gas as a vertical high speed gas jet into the reaction zone by reaction gas nozzle(s), forming local reaction gas jets surrounded by bubble-forming fluidized bed, gas decomposing leading to particle growth, wherein the reaction gas has fully or almost fully reacted to chemical equilibrium conversion before reaching the wall or bed surface. |
US08722136B2 |
Heat strengthening of a glass superstrate for thin film photovoltaic devices
Process and apparatus are generally provided for forming a thin film photovoltaic device. In one particular embodiment, the process includes: depositing a photovoltaic absorber layer on a glass substrate; heating the glass substrate to an anneal temperature; and quenching the glass substrate to cool the glass substrate to a quenched temperature in less than 10 seconds. The quenched temperature can be about 85° C. to about 200° C. less than the anneal temperature. The quenching atmosphere can have a quenching pressure of about 1 torr or more and can include an inert gas. |
US08722135B2 |
Method for discharging chemical solution
An object is to provide a chemical solution application apparatus capable of applying a chemical solution evenly and without irregularity by a spin coating method. A plurality of nozzles are provided for applying a chemical solution to an application object that is fixed over a stage. Each of the nozzles is individually mobile in vertical and horizontal directions. For this reason, controlling a discharging point or pattern is possible, and application responding to a wider viscosity range of chemical solutions is possible. By implementing the present invention, a chemical solution application apparatus equipped with a discharging method of a chemical solution by which a coating film having a small film thickness distribution over an entire substrate and an even thickness can be obtained, as well as for which use efficiency is improved by cutting down on waste of a chemical solution to be discharged. |
US08722132B2 |
Application of a coating on a medical device
Methods and devices for the provision of a coating on an implantable medical device. The coating includes a bio-absorbable carrier component. In addition to the bio-absorbable carrier component, a therapeutic agent component can also be provided. The methods and devices provide a coating having improved uniformity and coverage which in turn allow for greater control of the amount and dosage of the coating. |
US08722131B2 |
Comestible emulsions
Disclosed are comestible emulsions that comprise polyunsaturated fatty acids and methods of preparing them. The emulsions remain clear or semi-clear upon dilution. The emulsions comprise one or more polyunsaturated fatty acids or derivatives thereof, one or more emulsifiers, one or more organic solvents, and one or more polyols in a water solution. The emulsions are particularly suited for incorporation into beverages. |
US08722130B2 |
Heated buttermilk and cream for manufacturing cream cheese product
The present disclosure relates generally to the heating of buttermilk and cream for extended periods of time to provide a novel flavorant. The flavorant may be used to provide low-fat dairy products, such as low-fat cream cheese, with organoleptic properties similar to full-fat cream cheeses. The flavorant may also be incorporated into other food products to provide creamy and buttery flavors where desirable. |
US08722129B2 |
Process for producing modified gum arabic
The invention provides a method for efficiently improving emulsifying ability of gum arabic, in other words, a method for producing gum arabic with excellent emulsifying ability. Further, the present invention provides a method by which a gum arabic modified so as to have a high emulsifying ability can be obtained without involving the problem of forming syrupy masses or sticking to the vessel or the trouble of excessive dehydration or charring. The above-described methods can be carried out by heating gum arabic (unmodified) under dry conditions. Preferably, the method is carried out by heating gum arabic in such a manner that the loss-on-drying is not more than 3%. |
US08722128B2 |
Foamable oil-in-water emulsified oil composition for chilled-distribution whipped creams and whipped cream
A foamable oil-in-water emulsified oil composition for chilled-distribution whipped creams, characterized in that: the oil content is 20 to 40 wt %; the oil contains an oil (A) containing trigricerides in which the constituent fatty acids have total carbon atom numbers of 36 and 38 in a total amount 40 wt % and having a rising slip point of 30° C. or higher and an oil (B) selected from hardened palm kernel oils and a hardened coconut oils; the content of the oil (A) is 1 to 30 wt % with respect to the total amount of the oil; the content of the oil (B) is 5 to 30 wt % with respect to the total amount of the oil; the total content of the oils (A) and (B) is 15 to 50 wt % with respect to the total amount of the oil; the crystallinity of the oil, after the composition is stored at 5° C. for 4 days is 50% or more; and the difference between the crystallinity of the oil after the composition is stored at 5° C. for 1 hour and the crystallinity of the oil after the composition is stored at 5° C. for 1 hour time and additionally at 15° C. for 30 minutes is 2% or less. |
US08722125B2 |
Apparatus and method for demucilating, cleaning and washing depulped coffee
The present invention is developed in the farming machinery field used during the wet stage of the coffee and refers to an apparatus that allows carrying out the processes of demucilaging, cleaning and washing of the previously depulped coffee seedcases using a low water and power consumption. Said apparatus includes a mechanical feeding system for depulped beans, as well as a system for removing the mucilage and further washing of the beams that is constituted by a vertical rotor provided with metallic fingers that generate friction between the grains to be demucilaged, and also two metallic baskets, the first one is conical shaped—where a variable pressure zone between beans is generated, making possible a efficient detachment of the mucilage—, and the second one is cylindrical shaped one—zone of greater agitation between the beans and lower pressure between them and where a minimal amount of water is used for final washing—, which are built with square rods forming a continuous spiral which enables an easy evacuation of mucilage and other impurities through the horizontal slots due to the centrifugal force produced by the spin of a rotor. Finally, the present invention refers to a method for demucilaging, cleaning and washing depulped coffee by using of the above mentioned integral machine. |
US08722119B2 |
Process for producing fermented milk
The present invention relates to a process for producing fermented milk, including adding to a milk mix a starter in an amount of from 0.2 to 0.8% by weight with respect to the total amount of the milk mix, reducing the dissolved oxygen concentration in said mix to 5 ppm or less and conducting a fermentation after said addition of the starter and said reduction of the dissolved oxygen concentration |
US08722118B2 |
Method for flavoring cheese products
The present invention relates to a method for flavoring a cheese product by processing at least one initial cheese base, including a stage for the heat and mechanical kneading type treatment of the initial cheese base, after it has been split up, at a temperature T1 of at most 80° C., in order to secure a limited destructuring of the protein network of the initial cheese base, characterized in that at least one flavoring agent, selected from the group constituted by flavor fermenting agents that present an increased enzymatic activity and embrittlement of their cellular wall, flavor fermenting lysates, and amino group accepting compounds, is added to the initial cheese base and/or during the stage above. |
US08722109B1 |
Composition comprising plant extracts and essential oils
The composition for treating tumors is a natural tumor treatment made from plant extracts, animal secretions and essential oils. The composition includes a solid mixture which is taken with a liquid mixture. The solid mixture is a mixture of Dorema ammoniacum, castoreum, myrrh, Cistus creticus, Asarum europaeum, cucumber seed, Egyptian cucumber seed, pumpkin seed, watermelon seed, cantaloupe seed, psyllium husk, Astragalus tragacanthus, mastic, and lump sugar. Each of these solid ingredients is ground separately and then purified through sifting, draining and smoothing. Once ground and purified, the solid powders are mixed together into a homogenous mixture. These solids are delivered to the patient in pill, capsule, powder, solution or serum injection form. Approximately 12 grams of the solid mixture is taken with approximately 250 mL of a liquid mixture of the essential oils of Borago officinalis, fennel, Trachyspermum ammi, and Cichorium. |
US08722108B2 |
Cosmetic and/or pharmaceutical composition comprising an extract of carob as active agent for activating aquaporin expression
The invention relates to a cosmetic and/or pharmaceutical composition comprising, in a physiologically suitable medium, a carob peptide extract (Ceratonia siliqua L.) as an active agent for promoting aquaporin expression. The present invention also relates to the use of a carob peptide extract (Ceratonia siliqua L.), as an active agent for promoting aquaporin expression, in a cosmetic composition for improving the moisturization and the barrier function of the epidermis and for stimulating skin regeneration. The invention also relates to the use of this novel active agent for preparing a pharmaceutical, in particular dermatological, composition for regulating and/or stimulating aquaporin activity. The invention also relates to a cosmetic treatment method for preventing or combating dryness of the skin and mucous membranes and the manifestations of skin aging. |
US08722106B2 |
Lip balm composition
A lip balm composition of natural ingredients, comprising: 54-70 wt. % of one or more oils, 22-28 wt. % beeswax, 3-4 wt. % propolis, 3-5 wt. % pomace, 0.02-3.2 wt. % antioxidant, and optional ingredients, whereby all components add to 100 wt. %. |
US08722101B2 |
Use of iron(III) complex compounds
The present invention relates to novel therapeutic uses of iron(III) complex compounds with carbohydrates or derivatives thereof, in the preparation of a medicament for improving immune defence and/or brain performance. |
US08722095B2 |
Fluorescent nanocrystals encapsulated in an inorganic shell
The present invention relates to a method of preparing hybrid organo/mineral nanoparticles comprising an organic fluorescent crystalline core encapsulated in an inorganic shell, and to nanoparticles that can be obtained by said method. The method of the present invention comprises the following steps: (i) a sol-gel mixture able to be obtained by a process comprising the addition, in at least one organic solvent, in the presence of water, of a fluorescent organic compound and at least one metal alkoxide is sprayed; (ii) the sprayed sol-gel mixture is dried, by evaporating the solvent and the water that are present in the sol-gel mixture. The nanoparticles of the present invention can be used for example as a tracer in medical imaging or as a chemical sensor. |
US08722094B2 |
Solid dispersion and pharmaceutical composition of the same, and production processes thereof
A powdery porous carrier comprising a porous silicon-containing carrier is impregnated with a solution containing an organic solvent and an active ingredient hardly soluble in water, and the organic solvent is removed to give a solid dispersion having the active ingredient supported to the porous carrier without a treatment with a supercritical fluid. The porous silicon-containing carrier has a heating loss of not more than 4% by weight at a temperature of 950° C. for 2 hours (e.g., a spherical silicon-containing carrier such as a spherical porous silica). The porous silicon-containing carrier may be a spherical silica having a mean pore size of 10 to 40 nm and an oil absorption of 175 to 500 ml/100 g. A pharmaceutical composition (e.g., tablets, granules, or capsules) may be prepared from the solid dispersion and a pharmaceutically acceptable carrier. This invention provides a solid dispersion and a pharmaceutical composition (or a pharmaceutical preparation) which allows improvement in a solubility and a bioavailability of an active ingredient hardly soluble in water (e.g., a fibrate compound). |
US08722092B2 |
Nanoparticles made of amorphous cellulose
The present invention provides novel nanoscale cellulose particles and also a process for their production. The cellulose-based particles obtained have volume-averaged particle sizes of less than 300 nm. These nanoparticles are produced from amorphous cellulose or by amorphization of cellulose, optional subsequent hydrolysis and by input of energy into a water-containing medium after or during dispersion. |
US08722091B2 |
Preparation of submicron sized nanoparticles via dispersion lyophilization
The present invention relates to a process for preparing submicron sized nanoparticles of a poorly water soluble compound by lyophilizing a dispersion or microdispersion of a multiphase system having an organic phase and an aqueous phase, the organic phase having the poorly water soluble organic compound therein. The method is preferably used to prepare nanoparticles of a poorly water soluble, pharmaceutically active compound suitable for in vivo delivery, particularly by parenteral routes. |
US08722087B2 |
Titration dosing regimen for controlled release tramadol
A titration dosing regimen for the administration of controlled release tramadol analgesic to patients. The titration dosing regimen provides a significant reduction in the occurrence of adverse effects from the introduction of controlled released tramadol dosing, thus increasing patient compliance and medication tolerability. |
US08722084B2 |
Controlled release preparation
A controlled release preparation wherein the release of active ingredient is controlled, which releases an active ingredient for an extended period of time by staying or slowly migrating in the gastrointestinal tract, is provided by means such as capsulating a tablet, granule or fine granule wherein the release of active ingredient is controlled and a gel-forming polymer. Said tablet, granule or fine granule has a release-controlled coating-layer formed on a core particle containing an active ingredient. |
US08722082B2 |
Lipids and compositions for the delivery of therapeutics
The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structures XIV or XVII. |
US08722081B2 |
Hemostatic textile material
A hemostatic textile material to stop bleeding comprising a dialdehyde cellulose (DAC) carrier wherein the degree of oxidation of the dialdehyde cellulose varies from about 1.5% to 12%; and a blood coagulation factor selected from the group consisting of chitosan and gelatin; the blood coagulation factor being chemically immobilized thereon; and further optionally comprising a bacteriolytic agent selected from the group consisting of a lysozyme enzyme, silver nitrate, and chlorhexidine; and further optionally comprising a selected component that prevents hemolysis, the component selected from the group consisting of tranexamic acid or ε-aminocaproic acid chemically immobilized thereon. |
US08722077B2 |
Drug delivery coating for use with a stent
A coated medical device and a method of providing a coating on an implantable medical device result in a medical device having a bio-absorbable coating. The coating includes a bio-absorbable carrier component. In addition to the bio-absorbable carrier component, a therapeutic agent component can also be provided. The coated medical device is implantable in a patient to effect controlled delivery of the coating, including the therapeutic agent, to the patient. |
US08722075B2 |
Compositions and methods for promoting bone formation
A method for promoting bone formation is provided. More specifically, a method for promoting bone formation by promoting osteoclast formation is provided. In one embodiment, an implant comprising an implantable material and an osteoclast stimulating substance is provided. |
US08722073B2 |
Post irradiation shelf-stable dual paste direct injectable bone cement precursor systems and methods of making same
The present invention relates to a bone cement precursor system that is presented in the form of two shelf-stable pastes which have been terminally sterilized and are held in separate containers during product transport and storage. When the product is used during surgery, these pastes inject to a site of application through a static mixing device by the action of applied injection force. When the two pastes are mixed, they start to react to each other while injecting out. The resulting composition is highly biocompatible, osteoconductive, injectable, rapid setting and bioresorbable, and is useful in connection with bone repair procedures, for example, in the craniomaxillofacial, trauma and orthopedic areas. |
US08722069B2 |
Oil-in-water emulsion having improved sensory properties
An oil-in-water emulsion includes, for 100 wt % thereof: a) 0.1 to 10 wt % of an emulsifying system including, for 100 wt % thereof: (i) 5 to 95 wt % of the mixture of the reaction products of a reducing sugar and 1,12-octadecanediol essentially consisting of hydroxyl-octadecyl polyglycosides of formula (I): HO—R—O-(G)n-H (I) and of polyglycosyl octadecyl polyglycosides of formula (II): H-(G)m-O—R—O-(G)p-H (II), where, in formulas (I) and (II), G is the remainder of the reducing sugar and R is the divalent radical octadecane-diyl-1,12, and where n, m and p, identical or different, each are, independently of each other, a decimal number between 1 and 5; (ii) 95 to 5 wt % of 1,12-octadecanediol; b) 0.01 to 5 wt % of at least one thickening and/or gelling agent; c) 10 to 50 wt % of an oil phase; and d) 89.89 to 35 wt % of an aqueous phase. |
US08722068B2 |
Compositions and methods for surface abrasion with frozen particles
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue. |
US08722066B2 |
Devices and methods for weight control and weight loss
The present invention provides, compositions, devices, and methods for affecting, among other things, weight loss and/or weight control, by sequestering nutrients or other compounds such as toxins from absorption in the digestive tract. The compositions, devices, and methods employ one or more members made of a compressible, absorbent matrix material. In various embodiments, the matrix material is suitable for routine use. The compressible absorbent matrix material has a size, shape and/or geometry configured for efficient packing into a small space, and/or configured to absorb and substantially retain digested material in the stomach. The devices and compositions may further comprise one or more hydrogel(s), soluble or insoluble fibers, waxes and/or gums to provide the desired mechanical properties and/or absorptive or shielding properties. |
US08722064B2 |
Synthetic glucopyranosyl lipid adjuvants
Compounds, particularly, glucopyranosyl lipid adjuvant (GLA) compounds, having the following structure (I) are provided: or a pharmaceutically acceptable salt thereof, wherein L1, L2, L3, L4, L5, L6, L7, L8, L9, L10, Y1, Y2, Y3, Y4, R1, R2, R3, R4, R5, R6, are as defined herein. Pharmaceutical compositions, vaccine compositions, and related methods for inducing or enhancing immune responses, are also provided. |
US08722062B2 |
Multivalent meningococcal polysaccharide-protein conjugate vaccine
The present invention describes a combined vaccine that offers broad protection against meningococcal disease caused by the pathogenic bacteria Neisseria meningitidis. The vaccine is comprised of four distinct polysaccharide-protein conjugates that are formulated as a single dose of vaccine. Purified capsular polysaccharides from Neisseria meningitidis serogroups A, C, W-135, and Y are chemically activated and selectively attached to a carrier protein by means of a covalent chemical bond, forming polysaccharide-protein conjugates capable of eliciting long-lasting immunity to a variety of N. meningitidis strains in children as well as adults. |
US08722061B2 |
Antibody profiles characteristic of tuberculosis state
Serum antibody assays capable of distinguishing cases of inactive TB from cases of active TB include a combination of at least three M. tuberculosis protein antigens, at least one for which a positive response is consistent with inactive TB and antigens, and at least one for which a negative response is consistent with inactive TB. |
US08722042B2 |
Use of ventricular enlargement rate in intravenous immunoglobulin treatment of alzheimer's disease
The present invention relates to the use of MRI monitoring of ventricular enlargement rate as an objective measure for the purpose of assessing disease progression in patients suffering from Alzheimer's disease and for the purpose of determining therapeutic effectiveness of a treatment regimen for Alzheimer's patients. Methods for treating Alzheimer's Disease and monitoring therapeutic effectiveness are provided. |
US08722039B2 |
Gelatin-transglutaminase hemostatic dressings and sealants
An adhesive material for medical use comprising gelatin and a non-toxic cross-linking material such as transglutaminase. An optional embodiment of the invention includes dressings in which a layer of a transglutaminase is sandwiched between a first and second layer of gelatin. The hemostatic products are useful for the treatment of wounded tissue. |
US08722034B2 |
hUTC as therapy for Alzheimer's disease
Methods for treating Alzheimer's disease, or the symptoms of Alzheimer's disease, are provided. Some embodiments are to methods for treatment comprising administering cells obtained from human umbilical cord tissue, or administering pharmaceutical compositions comprising such cells or prepared from such cells, such as cell derivatives. Some embodiments are to methods for treatment comprising hUTC. Pharmaceutical compositions for use in the inventive methods, as well as kits for practicing the methods are also provided. |
US08722028B2 |
Ethylenic copolymers, compositions and methods of the same
The present disclosure relates to novel ethylenic copolymers comprising from 10% to 80% by weight, of at least one monomer of polyethylene glycol (meth)acrylate type, from 20% to 90% by weight, of at least one anionic monomer, and from 0% to 70% by weight, at least one additional nonionic hydrophilic monomer. The disclosure also relates to a composition, such as cosmetic or pharmaceutical compositions, comprising the copolymers and to a method of using the same. |
US08722026B2 |
Skin lightening compositions
Compositions and methods for lightening and/or depigmenting skin are provided, the compositions comprising compounds having the structure: or having the structure: as defined herein. |
US08722025B2 |
Cosmetic dermatological composition, cosmetic treatment method, and hyaluronic acid derivative
The invention relates to a cosmetic or dermatological composition comprising a hyaluronic acid derivative which comprises ureidopyrimidone units, to the said derivatives and to a cosmetic treatment method using them. |
US08722023B2 |
Depigmenting or brigthening cosmetic composition comprising at least one oxazolin as an active ingredient
The invention relates to the cosmetic use of at least one oxazolin as a depigmenting active ingredient in a depigmenting composition, and to the associated cosmetic treatment method. The invention also relates to the use of at least one oxazolin for preparing an active medicament as a depigmenting agent, and to a depigmenting cosmetic composition comprising at least one oxazolin as a depigmenting active ingredient. |
US08722021B2 |
Foamable carriers
The invention relates to an alcohol-free cosmetic or therapeutic foam carrier comprising water, a hydrophobic organic carrier, a foam adjuvant agent, a surface-active agent and a gelling agent. The cosmetic or therapeutic foam carrier does not contain aliphatic alcohols, making it non-irritating and non-drying. The alcohol-free foam carrier is suitable for inclusion of both water-soluble and oil soluble therapeutic and cosmetic agents. |
US08722020B2 |
Hydroxylated contrast enhancement agents
In one aspect, the present invention provides a contrast enhancement agent comprising an iron chelate having structure I and salts thereof wherein R1 is independently at each occurrence a hydroxy group, a C1-C3 hydroxyalkyl group, or a C1-C3 alkyl group, and b is 0-4; R2-R7 are independently at each occurrence hydrogen, a C1-C3 hydroxyalkyl group, or a C1-C3 alkyl group, with the proviso that at least one of R1-R7 is a hydroxy group or a C1-C3 hydroxyalkyl group; and wherein Q is one or more charge balancing counterions. Also provided are a metal chelating ligand having structure IX and medical formulations comprising the contrast enhancement agent I. |
US08722018B2 |
Method for preparing nanoparticles covered with a gem-bisphosphonate stabilizing layer coupled to hydrophilic distribution ligands
A novel method for preparing nanoparticles for medical imaging, including a metal core, an organic stabilizing layer containing gem-bisphosphonate compounds and at least one hydrophilic biodistribution ligand. |
US08722017B2 |
Fluorescent magnetic nanoprobes, methods of making, and methods of use
Embodiments of the present disclosure provide for nanoprobes, methods of imaging, methods of imaging a target, methods of making nanoprobes, and the like. |
US08722013B2 |
Use of R(+)-alpha-lipoic acid for cryptogenic neuropathy
The present invention relates to the use of R(+)-alpha-lipoic acid ((R)-5-(1,2-dithiolan-3-yl)valeric acid) and/or of a physiologically acceptable derivative of this compound for cryptogenic neuropathy. |
US08722003B1 |
Apparatus and method to produce synthetic gas
A system and method of capturing carbon dioxide from a flow of raw synthesis gas generated in a gasification system are provided. The carbon capture system includes an acid gas removal subsystem configured to generate a flow of reduced acid gas content syngas, a flow of hydrogen sulfide (H2S) lean gas, and a first flow of H2S-rich gas from a stream of particulate-free raw syngas, an H2S selective membrane separator, said H2S selective membrane separator configured to separate the flow of H2S-lean gas from the AGR into a second flow of H2S-rich gas and a flow of CO2 gas, and a sulfur recovery unit (SRU) coupled in flow communication with said H2S membrane separator downstream of said membrane separator, said SRU configured to generate a flow of elemental sulfur and a flow of tail gas from the first flow of H2S-rich gas and the second flow of H2S-rich gas. |
US08721999B2 |
Process for simultaneous production of potassium sulphate, ammonium sulfate, magnesium hydroxide and/or magnesium oxide from kainite mixed salt and ammonia
Kainite mixed salt is treated with water to obtain solid schoenite and a schoenite end liquor. The latter is desulphated using recycled CaCl2 and thereafter evaporated to obtain camallite crystals, from which KCl is recovered, and a liquor rich in MgCl2. Gypsum produced during desulphatation is reacted with aqueous ammonia and CO2 to produce ammonium sulphate and calcium carbonate. The calcium carbonate is calcined to obtained CaO and CO2. The CaO is slaked and reacted with the MgCl2-rich liquor generated above to produce slurry of Mg(OH)2 in aqueous CaCl2. To this surface modifying agent is added while hot and, after cooling, the slurry yields surface modified Mg(OH)2. The filtrate rich in CaCl2 is recycled for desulphatation process above. The solid surface modified Mg(OH)2 may he calcined to produced MgO. The schoenite and KCl are reacted to produce solid sulphate of potash. |
US08721996B2 |
Reactor for continuous heterogeneously catalyzed partial dehydrogenation of at least one hydrocarbon to be dehydrogenated
A shell which encloses an interior and has at least one first orifice for feeding at least one gas stream into the interior and at least one second orifice for withdrawing a gas stream fed to the interior beforehand via the at least one first orifice from the interior, the surface of the shell, on its side in contact with the interior, being manufactured at least partly, in a layer thickness of at least 1 mm, from a steel which has a specific elemental composition, and in the interior, a process for continuous heterogeneously catalyzed partial dehydrogenation of at least one hydrocarbon to be dehydrogenated is carried out in a reactor which is manufactured from the steel on its side in contact with the reaction gas. |
US08721994B2 |
Apparatus for recovering hydroprocessed hydrocarbons with two strippers and common overhead recovery
An apparatus is disclosed for recovering hydroprocessing effluent from a hydroprocessing unit utilizing a hot stripper and a cold stripper. The cold stripper and the hot stripper utilize a common overhead recovery apparatus. |
US08721993B2 |
Magnetic clamps for laboratory shakers
A clamp for an Erlenmeyer flask or other laboratory containers or racks uses nickel-coated, rare earth magnets to secure the clamp to a platform for a laboratory shaker. The base of the clamp has downwardly extending positioning bosses that seat in holes or indentations on the shaker platform to prevent horizontal sliding of the clamp when the shaker is in use. A removable and replaceable, elastomeric cover for the base of the flask clamp provides cushioning and prevents spinning of the flask when the shaker is in use. |
US08721991B2 |
Microfluidic device for controlled aggregation of spider silk
The present invention is directed to a device and method of controlling the phase separation of one or a mixture of two or more spider silk proteins, leading to the defined and controllable assembly of the said silk protein(s) to defined morphologies, such as spheres, nano fibrils, threads, etc. |
US08721990B2 |
Assay device
Disclosed is an assay device for the determination of the presence and/or extent if an analyte in a liquid sample over an extended concentration range comprising a first assay and a second assay, wherein the first assay for an analyte comprises a first flow-path having a sole detection zone capable of immobilizing a labelled binding reagent and the second assay for said analyte comprises a second flow-path having a sole detection zone capable of immobilizing a labelled binding reagent, wherein the presence of labelled binding reagent at the detection zones provides an indication of the presence and/or extent of analyte in said liquid sample. |
US08721987B1 |
Refuse disinfection system
A system for disinfecting regulated refuse using steam disinfection used a refuse container where the regulated refuse is deposited. Temperature sensors are positioned below and above the refuse to detect the temperature of the disinfecting process, while a recording device operationally connected to the temperature sensors creates an identifying chart, which provides for identification of the time and temperature of processing, origin of the regulated refuse, as well as date and location of the processing. |
US08721986B2 |
Freshening clip cabin air cleaner
A freshening clip cabin air cleaner includes an airflow permeable filter media arranged in and supported in an annular frame member. Support members may be provided at one or both airflow face of the filter media and includes an elongated clip mounting means mounting the freshening clip cabin air cleaner to the air vent grill. A scented air freshening material having volatizing aromatic agents is arranged on or in at least one of the support members, the annular frame or the filter media. |
US08721984B2 |
Device and method for gas sterilization
A system for gas sterilization includes a sterilization chamber, a source of sterilant gas, and a sterilant gas remediation mechanism. Embodiments relate to systems and methods for delivering humidified air to a sterilization chamber, systems and methods for removing gaseous NO2 from an exhaust gas stream of a sterilization chamber, systems and methods for removing and replacing a source of sterilant gas, an exhaust gas scrubber and/or supplies for a humidification system. Some embodiments relate to hardware and software for user interface in a sterilizing device and hardware and software for control of a sterilization cycle. Some embodiments relate to chamber, chassis and door configurations of a sterilizer. |
US08721981B2 |
Spiral recuperative heat exchanging system
A heat exchanging system is provided. The heat exchanging system includes multiple plates wound spirally around a reaction chamber. The multiple plates also form multiple channels that operate as a counter flow recuperator terminating within the reaction chamber. |
US08721980B2 |
Systems and methods of producing chemical compounds
Systems and methods of producing chemical compounds are disclosed. An example chemical production system includes an intake chamber having intake ports for entry of a gas mixture. An igniter ignites the gas mixture in the intake chamber. A nozzle restricts exit of the ignited gas mixture from the intake chamber. An expansion chamber cools the ignited gas with a cooling agent. The expansion chamber has an exhaust where the cooled gas exits the expansion chamber. A chemical compound product is formed in the expansion chamber. |
US08721978B2 |
Catalyst carrier
Disclosed is a catalyst carrier which is used for carrying a catalyst thereon. The catalyst carrier is characterized in that the apparent specific heat measured at 800° C. is 1.8 times or more greater than that measured at room temperature, wherein the apparent specific heat means a charge heat amount required for substantially increasing the temperature of a unit mass (kg) by 1 K, inclusive of the influence of endotherm or exotherm caused by change in crystalline form, partial melting, coagulation, phase transformation, vitrification, amorphous-formation, crystallization and the like. |
US08721976B2 |
Diesel exhaust gas purification catalyst and diesel exhaust gas purification system
A diesel exhaust gas purification catalyst contains a substrate, and a catalyst layer formed on the substrate. The catalyst layer contains a carrier, a noble metal and/or an oxide thereof supported by the carrier, and a composite oxide of cerium and one or more Group III and/or Group IV elements. The diesel exhaust gas purification catalyst when in use is disposed on an upstream side of an exhaust gas stream with respect to a denitration catalyst. |
US08721975B2 |
Plant for urea production
Plant for urea production from ammonia and carbon dioxide having a so-called high-pressure section which comprises a synthesis reactor and a condensation unit (7, 107) positioned inside the reactor, all substantially operating at the same pressure. |
US08721968B2 |
Optical lens system and method for microfluidic devices
An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic device. The imaging path provides for transmission of one or more fluorescent emission signals derived from one or more samples in the at least one chamber of the at least one microfluidic device. The chamber has a chamber size, the chamber size being characterized by an actual spatial dimension normal to the imaging path. The apparatus also includes an optical lens system coupled to the imaging path. The optical lens system is adapted to transmit the one or more fluorescent signals associated with the chamber. |
US08721966B2 |
Chemical analyzer, method for dispensing and dilution cup
A method for dispensing a sample solution and a reagent into a container in a chemical analyzer includes a first step of dispensing a reagent into a container, a second step of dispensing a sample solution into the container after the first step, and a third step of dispensing the reagent into the container after the second step. A dilution cup includes an inner face where a diameter of a horizontal section increases on at least one position from a bottom to a top, an opening portion surrounding an opening, where a sample solution is dispensed, located on or near the top, a reagent aperture portion surrounding an aperture where a reagent is dispensed such that the sample solution and the reagent create an upswing spiral flow, and a drain aperture portion surrounding a drain aperture, where a mixed solution of the sample solution and the reagent is discharged, located on or near the bottom. |
US08721965B2 |
Transporting apparatus and specimen analyzing apparatus
A transporting apparatus for transporting a specimen rack holding a specimen container containing a specimen, comprising: an engage unit capable of engaging with the specimen rack; and a moving mechanism for moving the engage unit in a transport direction of the specimen rack, the transport direction including a first direction and a second direction opposite to the first direction, wherein the engage unit comprises: a pair of engage members, capable of mutually approaching and separating relative to the transport direction, and engaging with the specimen rack gaplessly relative to the transport direction by the approaching operation or the separating operation; and a driver for driving the pair of engage members so as to perform the approaching operation and the separating operation. A specimen analyzing apparatus is also disclosed. |
US08721962B2 |
Methods, devices, compositions and systems for improved scent delivery
Systems, devices, methods, and compositions that improve the scent perception for a user. Improved scent perception is achieved by presenting alternating scents and by varying levels of output of scents, as well as by minimizing device clogging, thereby improving evaporation profiles. |
US08721961B2 |
Au—Sn alloy bump including no large void and method of producing same
An Au—Sn alloy bump that does not include large voids and a method of producing the same are provided. The Au—Sn alloy bump that does not include large voids comprises a composition containing Sn: 20.5 to 23.5 mass % and the balance Au and unavoidable impurities, and a structure where 0.5 to 30 area % of Sn-rich primary crystal phase is crystallized in the matrix. |
US08721957B2 |
Method and device for forming containers with counter-pressure
A forming method, in a mold fitted with a wall forming a cavity, of a container from an intermediate container including at least one lateral protrusion projecting toward the exterior of the container. The method includes a boxing operation of pushing the lateral protrusion by an insert movably mounted with respect to the mold between a retracted position in which the insert is retracted into a recess formed in the wall and a deployed position in which the insert protrudes with respect to the wall, in order to form, by overturning, a hollow reserve projecting toward the interior of the container. Also included is an operation to pressurize the intermediate container, including, prior to the boxing operation, injecting a fluid under pressure into the intermediate container; and a local pressurization operation, prior to the boxing operation, of injecting a fluid under pressure into the volume defined in said recess between the lateral protrusion and the insert. |
US08721956B2 |
Method of forming a fluid receptacle
A fluid receptacle may include an outer wall defining a periphery of the fluid receptacle, and an inner wall. The inner wall may be connected to the outer wall at certain locations and spaced from the outer wall at other locations providing gaps between the outer wall and the inner wall. In some implementations, the inner wall may be complete or continuous and liquid fuel may be contained within the inner wall. In other implementations, liquid fuel may be received between the inner and outer walls. |
US08721954B2 |
Techniques for pitch densification
In some examples, a method for densifying a material via pitch comprises inserting the material to be densified into a mold, wherein the mold is part of an apparatus. The apparatus may include a ram configured to apply a ram pressure sufficient to force a pitch into the mold to densify the material, a gas source configured to apply a gas pressure sufficient to force the pitch into the mold to densify the material, and a vacuum source operable to create a vacuum pressure in the mold at least prior to application of either the ram pressure or the gas pressure. The method may further comprise densifying the material in the mold via pitch using a selectable one of the ram, the gas source, the ram and the vacuum source, or the gas source and the vacuum source. |
US08721945B2 |
Actinically curable silicone hydrogel copolymers and uses thereof
The present invention provides inks and methods for making colored silicone hydrogel contact lenses. The ink of the invention comprises an actinically-curable binder copolymer comprising fluorine-containing segments and is characterized by having capability to be cured actinically or thermally to form a colored film on a molding surface of a mold or a silicone hydrogel contact lens and by having an increased durability in a solvated state in a silicone-hydrogel lens formulation in relation to a control colored film obtained from a control ink including an actinically-curable fluorine-free binder copolymer. The invention also provides methods for making colored silicone hydrogel contact lenses based on print-on-mold processes for producing colored contact lenses. |
US08721942B2 |
Composite membrane including coating of polyalkylene oxide and acetophenone compounds
Composite membranes including a coating of polyalkylene oxide and acetophenone compounds along with various methods for making and using the same. In one embodiment, the composite membrane comprises a thin film polyamide layer including a coating of a reaction product of a polyalkylene oxide compound and an acetophenone compound. In another embodiment, the coating comprises a polymer including alkylene oxide repeating units and one or more acetophenone functional groups. |
US08721938B2 |
Methods for making layered dental appliances
A system and method for making a layered dental appliance. The system can include a mold comprising a negative of an outer shape of a layered dental appliance, and a dental core dimensioned to be at least partially received in the mold. The method can include positioning a first slurry in the mold, and pressing the dental core into the first slurry in the mold to form a first article comprising the dental core and a first layer formed from the first slurry. The method can further include removing the first article from the mold, and firing the first article. The method can further include positioning a second slurry in the mold, and pressing the first article into the second slurry in the mold to form a second article comprising the dental core, the first layer, and a second layer formed from the second slurry. |
US08721937B2 |
Method for making polyamide particles
This disclosure relates to a method of preparing polyamide particles. The method include spray drying a solution containing a polyamide to form polyamide particles having an average diameter of between about 0.5 μm and about 10 μm and at least about 85% of the polyamide particles having a diameter distribution of no more than about 1.5 μm. |
US08721934B2 |
Method of removing excess lens forming material from a molded ophthalmic lens such as a contact lens
There is described a method of removing excess lens forming material from a molded ophthalmic lens (1), such as the peripheral region of a contact lens. In order to form a lens (1) a lens forming material is polymerized and/or cross-linked within a mold cavity of a mold comprising female and male mold halves. The mold is opened by moving the female and male mold halves apart from each other. The formed lens (1) is supported on a carrier (3) such, that a front surface (2) of the lens (1) is exposed. Residues of non-polymerized and/or non-cross-linked lens forming material are removed mechanically by contacting the exposed surface (2) of the formed lens (1) for a period of time of about 0.5 seconds to about 4 seconds, preferably about 0.8 seconds to about 2 seconds, with a cleaner (7) having a hardness which is smaller than that of the polymerized and/or cross-linked lens forming material. There is also described a device (5) for carrying out the method. |
US08721929B2 |
Polythiophene polyanion complexes in homopolar organic solvents
The invention relates to novel polythiophene-polyanion complexes which are soluble or dispersible in nonpolar organic solvents, and to the use thereof. |
US08721927B2 |
Production of synthesis gas from solvent deasphalting process bottoms in a membrane wall gasification reactor
A cost-effective solution for the disposal of solvent deasphalting process bottoms that include spent solid adsorbent material containing ash-producing constituents, asphalt and process reject materials is provided by introducing them in the form of a flowable slurry into a membrane wall gasification reactor to produce a synthesis gas and, optionally, subjecting the synthesis gas to a water-gas shift reaction to produce a more hydrogen-rich product stream; process steam and electricity are produced by recovering the sensible heat values from the hot synthesis gas. |
US08721923B2 |
Metal sulfide and rare-earth phosphate nanostructures and methods of making same
The present invention provides a method of producing a crystalline metal sulfide nanostructure. The metal is a transitional metal or a Group IV metal. In the method, a porous membrane is placed between a metal precursor solution and a sulfur precursor solution. The metal cations of the metal precursor solution and sulfur ions of the sulfur precursor solution react, thereby producing a crystalline metal sulfide nanostructure. |
US08721922B2 |
Printable light-emitting compositions
Disclosed herein are compositions comprising an electron transport compound, an emissive compound, and an organic solvent. The emissive compound comprises an organic indium complex attached to a nanoparticle core. These compositions are useful in fabricating light emitting devices and can be deposited on a substrate via a printing process. |
US08721910B2 |
Process for manufacturing an integrated membrane of nozzles in MEMS technology for a spray device and spray device using such membrane
A process for manufacturing a membrane of nozzles of a spray device, comprising the steps of laying a substrate, forming a membrane layer on the substrate, forming a plurality of nozzles in the membrane layer, forming a plurality of supply channels in the substrate, each supply channel being substantially aligned in a vertical direction to a respective nozzle of the plurality of nozzles and in direct communication with the respective nozzle. |
US08721907B2 |
Method and system for milling and imaging an object
A system and a method for milling and inspecting an object. The method may include performing at least one iteration of a sequence that includes: milling, by a particle beam, a first surface of the object, during a first surface milling period; obtaining, by an electron detector, an image of a second surface of the object during at least a majority of the first surface milling period; wherein the object is expected to comprise an element of interest (EOI) that is positioned between the first and second surfaces; milling, by the particle beam, the second surface of the object during a second surface milling period; wherein each of the first surface milling period and the second surface milling period has a duration that exceeds a long duration threshold; obtaining by the electron detector an image of the first surface of the object during at least a majority of the second surface milling period. |