Document Document Title
US08698197B2 Tetra-lateral position sensing detector
The present invention is directed to a position sensing detector made of a photodiode having a semi insulating substrate layer; a buffered layer that is formed directly atop the semi-insulating substrate layer, an absorption layer that is formed directly atop the buffered layer substrate layer, a cap layer that is formed directly atop the absorption layer, a plurality of cathode electrodes electrically coupled to the buffered layer or directly to the cap layer, and at least one anode electrode electrically coupled to a p-type region in the cap layer. The position sensing detector has a photo-response non-uniformity of less than 2% and a position detection error of less than 10 μm across the active area.
US08698196B2 Low capacitance transient voltage suppressor (TVS) with reduced clamping voltage
A low capacitance transient voltage suppressor with reduced clamping voltage includes an n+ type substrate, a first epitaxial layer on the substrate, a buried layer formed within the first epitaxial layer, a second epitaxial layer on the first epitaxial layer, and an implant layer formed within the first epitaxial layer below the buried layer. The implant layer extends beyond the buried layer. A first trench is at an edge of the buried layer and an edge of the implant layer. A second trench is at another edge of the buried layer and extends into the implant layer. A third trench is at another edge of the implant layer. Each trench is lined with a dielectric layer. A set of source regions is formed within a top surface of the second epitaxial layer. The trenches and source regions alternate. A pair of implant regions is formed in the second epitaxial layer.
US08698194B2 Semiconductor integrated circuit with high withstand voltage element forming trench isolation on substrate
A first annular isolation trench is formed in a periphery of an element region, and a second annular isolation trench is formed around the first annular isolation trench with a predetermined distance provided from the first annular isolation trench, and a semiconductor layer between the first annular isolation trench and the second annular isolation trench is separated into a plurality of portions by a plurality of linear isolation trenches formed in the semiconductor layer between the first annular isolation trench and the second annular isolation trench, and the semiconductor layer (source-side isolation region) which opposes a p-type channel layer end portion and is located between the first annular isolation trench and the second annular isolation trench is separated from other semiconductor layers (drain-side isolation regions) by the linear isolation trenches.
US08698193B2 Light emitting device and method for manufacturing the same
The light emitting device of the invention includes a first electrode, a second electrode, and a carrier formed between the first electrode and the second electrode and containing germanium light emitters, wherein the germanium light emitters contain germanium oxide in which at least part of the germanium oxide has oxygen deficiency and have a wavelength peak of emission in both or either the range of 250 to 350 nm and/or the range of 350 to 500 nm when a potential difference is applied to the first electrode and the second electrode.
US08698192B2 Semiconductor light emitting device having a p-type semiconductor layer with a p-type impurity
According to one embodiment, a semiconductor light emitting device includes an n-type semiconductor layer, a p-type semiconductor layer, a light emitting part, and a p-side electrode. The light emitting part is provided between the n-type and the p-type semiconductor layers, and includes a plurality of barrier layers and a plurality of well layers. The p-side electrode contacts the p-type semiconductor layer. The p-type semiconductor layer includes first, second, third, and fourth p-type layers. The first p-type layer contacts the p-side electrode. The second p-type layer contacts the light emitting part. The third p-type layer is provided between the first p-type layer and the second p-type layer. The fourth p-type layer is provided between the second p-type layer and the third p-type layer. The second p-type layer contains Al and contains a p-type impurity in a lower concentration lower than that in the first concentration.
US08698191B2 Ultraviolet light emitting diode with AC voltage operation
Ultraviolet light emitting illuminator, and method for fabricating same, comprises an array of ultraviolet light emitting diodes and a first and second terminal. When an alternating current is applied across the first and second terminals and thus to each of the diodes, the illuminator emits ultraviolet light at a frequency corresponding to that of the alternating current. The illuminator includes a template with ultraviolet light emitting quantum wells, a first buffer layer with a first type of conductivity and a second buffer layer with a second type of conductivity, all deposited preferably over strain-relieving layer. A first and second metal contact are applied to the semiconductor layers having the first and second type of conductivity, respectively, to complete the LED. The emission spectrum ranges from 190 nm to 369 nm. The illuminator may be configured in various materials, geometries, sizes and designs.
US08698183B2 Light emitting diode and method for manufacturing the same
A light emitting device includes a substrate having a top surface and an bottom surface and a light emitting structure on the substrate, disposed closer to the substrate top surface than the substrate bottom surface, having an n-type conductive type semiconductor layer, a p-type conductive type semiconductor layer, and an active layer. The light emitting device also includes a transparent electrode layer, a first electrode, and a second electrode. The substrate has side surfaces extending from the substrate bottom surface to the substrate top surface, the side surfaces inclined outwardly as the substrate extends in a direction from the substrate bottom surface to the substrate top surface. The transparent electrode layer overlaps more than 50% of a total area of the substrate bottom surface, and a part of light generated by the light emitting structure is emitted to outside via the transparent electrode layer.
US08698179B2 Cathode for organic light emitting device and organic light emitting device using the cathode
In one aspect, a cathode including the first metal layer, the transparent conductive layer formed on the first metal layer, and the second metal layer formed on the transparent conductive layer is applied to the organic light emitting device and thicknesses of the first metal layer, the transparent conductive layer, and the second metal layer are controlled so that the external light reflection of the organic light emitting device is prevented. The cathode may further include the third metal layer formed on the second metal layer.
US08698174B2 Semiconductor light emitting device
This invention relates to a semiconductor light-emitting device including a semiconductor light-emitting chip and a transparent carrier. The semiconductor light-emitting chip includes an active layer and transparent substrate. The active layer emits light under a bias. At least a portion of the light emitted from the active layer enters into the transparent carrier through the transparent substrate. The semiconductor light-emitting chip is coupled to the transparent carrier through the transparent substrate. The area of the transparent carrier is larger than that of the active layer.
US08698169B2 Organic light emitting diode display
An organic light emitting diode (OLED) display includes a first electrode including a conductive black layer, a second electrode facing the first electrode, and an organic emission layer provided between the first electrode and the second electrode.
US08698166B2 Light emitting chip package module and light emitting chip package structure and manufacturing method thereof
A light emitting chip package module includes a substrate, a light emitting chip package structure, and a magnetic device. The substrate has a surface. The light emitting chip package structure is disposed on the surface of the substrate. The light emitting chip package structure includes a carrier, a light emitting chip, and a sealant. The light emitting chip is disposed on and electrically connected to the carrier. The sealant is disposed on the carrier and covers the light emitting chip. The magnetic device is disposed next to the light emitting chip package structure to apply a magnetic field to the light emitting chip.
US08698165B2 Graphene channel-based devices and methods for fabrication thereof
Graphene-channel based devices and techniques for the fabrication thereof are provided. In one aspect, a semiconductor device includes a first wafer having at least one graphene channel formed on a first substrate, a first oxide layer surrounding the graphene channel and source and drain contacts to the graphene channel that extend through the first oxide layer; and a second wafer having a CMOS device layer formed in a second substrate, a second oxide layer surrounding the CMOS device layer and a plurality of contacts to the CMOS device layer that extend through the second oxide layer, the wafers being bonded together by way of an oxide-to-oxide bond between the oxide layers. One or more of the contacts to the CMOS device layer are in contact with the source and drain contacts. One or more other of the contacts to the CMOS device layer are gate contacts for the graphene channel.
US08698164B2 Vertical GaN JFET with gate source electrodes on regrown gate
A semiconductor structure includes a GaN substrate with a first surface and a second surface. The GaN substrate is characterized by a first conductivity type and a first dopant concentration. A first electrode is electrically coupled to the second surface of the GaN substrate. The semiconductor structure further includes a first GaN epitaxial layer of the first conductivity type coupled to the first surface of the GaN substrate and a second GaN layer of a second conductivity type coupled to the first GaN epitaxial layer. The first GaN epitaxial layer comprises a channel region. The second GaN epitaxial layer comprises a gate region and an edge termination structure. A second electrode coupled to the gate region and a third electrode coupled to the channel region are both disposed within the edge termination structure.
US08698161B2 Semiconductor structures having directly bonded diamond heat sinks and methods for making such structures
A semiconductor structure is bonded directly to a diamond substrate by Van der Waal forces. The diamond substrate is formed by polishing a surface of diamond to a first degree of smoothness; forming a material, such as diamond, BeO, GaN, MgO, or SiO2 or other oxides, over the polished surface to provide an intermediate structure; and re-polishing the material formed on the intermediate structure to a second degree of smoothness smoother than the first degree of smoothness. The diamond is bonded to the semiconductor structure, such as GaN, by providing a structure having bottom surfaces of a semiconductor on an underlying material; forming grooves through the semiconductor and into the underlying material; separating semiconductor along the grooves into a plurality of separate semiconductor structures; removing the separated semiconductor structures from the underlying material; and contacting the bottom surface of at least one of the separated semiconductor structures to the diamond substrate.
US08698154B2 Array substrate for fringe field switching mode liquid crystal display device
An array substrate for a fringe field switching mode LCD device includes a pixel electrode having a plate shape in a pixel region; and a common electrode including a plurality of bar-type openings that correspond to the pixel electrode and long axes of which are inclined at a first angle in a clockwise direction or counterclockwise direction with respect to a normal line perpendicular to the gate line, wherein a data line is formed in a zigzag shape, wherein two adjacent data lines among three adjacent data lines are disposed in parallel with each other and the other data line is linearly symmetrical with respect to the two adjacent data lines, and wherein the long axis of each of the plurality of bar-type openings is disposed in parallel with one of data lines that define the pixel region and are located at both sides of the pixel region.
US08698149B2 Liquid crystal display and array substrate
An embodiment of the disclosed technology discloses an array substrate comprising: a base substrate; a first layer transparent common electrode formed on the base substrate; a gate metal common electrode formed on the first layer transparent common electrode; an insulation layer formed on the gate metal common electrode, with via holes being formed in the insulation layer; and a second layer transparent common electrode formed on the insulation layer. A side portion of via holes is in contact with the gate metal common electrode, another side portion is in contact with the first layer transparent common electrode, such that the second layer transparent common electrode is connected electrically with the first layer transparent common electrode and the gate metal common electrode in the via holes.
US08698148B2 Display devices and fabrication methods thereof
A display device and a fabrication method thereof are provided. The display device includes a first metal layer disposed on a display area and a peripheral area. An insulating layer covers the first metal layer. A patterned semiconductor layer is disposed on the insulating layer at the display area. A second metal layer is disposed on the patterned semiconductor layer and the insulating layer at the peripheral area. A transparent conductive layer directly covers the second metal layer. A protective layer completely covers the second metal layer, the patterned semiconductor layer and the transparent conductive layer. The protective layer includes a first portion, a second portion and a through hole, wherein the first portion has a height which is higher than a height of the second portion.
US08698147B2 Organic light emitting display device comprising a metal diffusion medium layer and method of manufacturing the same
Provided are an organic light emitting display device and a method of manufacturing the same. The organic light emitting display device includes a thin-film transistor (TFT), which includes an active layer, a gate electrode, and source/drain electrodes; an organic electroluminescent device electrically connected to the TFT and includes a pixel electrode formed on the same layer as the gate electrode, an intermediate layer including an organic light emitting layer, and a counter electrode that are stacked in the order stated; and a capacitor, which includes a bottom electrode, which is formed on the same layer and of the same material as the active layer and is doped with an impurity; a top electrode formed on the same layer as the gate electrode; and a metal diffusion medium layer formed on the same layer as the source/drain electrodes and is connected to the bottom electrode.
US08698143B2 Display device
An aperture ratio of a semiconductor device is improved. A driver circuit and a pixel are provided over one substrate, and a first thin film transistor in the driver circuit and a second thin film transistor in the pixel each include a gate electrode layer, a gate insulating layer over the gate electrode layer, an oxide semiconductor layer over the gate insulating layer, source and drain electrode layers over the oxide semiconductor layer, and an oxide insulating layer in contact with part of the oxide semiconductor layer over the gate insulating layer, the oxide semiconductor layer, and the source and drain electrode layers. The gate electrode layer, the gate insulating layer, the oxide semiconductor layer, the source and drain electrode layers, and the oxide insulating layer of the second thin film transistor each have a light-transmitting property.
US08698135B2 Plasma-chlorinated electrode and organic electronic devices using the same
A method is disclosed for elevating the work function of conductive layers such as indium tin oxide by chlorine-containing plasma exposure or etching. Also disclosed are electronic devices such as organic light-emitting diodes and organic photovoltaic cells with a chlorine plasma-treated conductive layer as the hole-injecting or hole-accepting electrode. The performance of the devices is enhanced due to an increased work function of the plasma-treated electrode.
US08698133B2 Organic electroluminescent device comprising a polymer obtained by polymerizing a polymerizable compound capable of exhibiting charge transportability and method for manufacturing the same
An organic electroluminescent device includes a pair of electrodes and a plurality of organic layers disposed between the electrodes, and one of the organic layers includes an organic material forming the organic layers and a polymer obtained by polymerizing a polymerizable compound capable of exhibiting charge portability.
US08698132B2 Functional molecular element, manufacturing method thereof, and functional molecular device
A functional molecule (10) is constructed of electrodes (5,6), which are formed of pSi (polysilicon) and are opposing each other, and a molecular array structure (7), and the molecular array structure is formed of interface modifier molecules (2), which are covalently coupled to surfaces of the electrodes (5,6) to modify the surfaces, and driver molecules (1) repeatedly stacked in one direction between the interface modifier molecules. The interface modifier molecules each have a nearly discoid skeleton of a π-electron conjugated system and side chains, are arranged with planes of their skeletons lying substantially in parallel to the surfaces of both the electrodes, and are covalently coupled at their side chains to Si atoms in both the electrodes. The driver molecules are of a π-electron conjugated system, and upon application of an electrical field, change in structure or orientation and hence change in dielectric constant, in other words, conductivity. The driver molecules are functional molecules of a complex having a Zn ion approximately at its center. The interface modifier molecules and driver molecules are stacked together by intermolecular π-π stacking, and so the driver molecules themselves.
US08698128B2 Gate-all around semiconductor nanowire FET's on bulk semicoductor wafers
Non-planar semiconductor devices are provided that include at least one semiconductor nanowire suspended above a semiconductor oxide layer that is present on a first portion of a bulk semiconductor substrate. An end segment of the at least one semiconductor nanowire is attached to a first semiconductor pad region and another end segment of the at least one semiconductor nanowire is attached to a second semiconductor pad region. The first and second pad regions are located above and are in direct contact with a second portion of the bulk semiconductor substrate which is vertically offsets from the first portion. The structure further includes a gate surrounding a central portion of the at least one semiconductor nanowire, a source region located on a first side of the gate, and a drain region located on a second side of the gate which is opposite the first side of the gate.
US08698116B2 Extreme ultra violet light source apparatus
An extreme ultraviolet light source apparatus using a spectrum purity filter capable of obtaining EUV light with high spectrum purity. The apparatus includes a chamber; a target supply unit for supplying a target material; a driver laser using a laser gas containing a carbon dioxide gas as a laser medium, for applying a laser beam to the target material to generate plasma; a collector mirror for collecting and outputting the extreme ultraviolet light radiated from the plasma; and a spectrum purity filter provided in an optical path of the extreme ultraviolet light, for transmitting the extreme ultraviolet light and reflecting the laser beam, the spectrum purity filter including a mesh having electrical conductivity and formed with an arrangement of apertures having a pitch not larger than a half of a shortest wavelength of the laser beam applied by the driver laser.
US08698114B2 Extreme ultraviolet light source device, laser light source device for extreme ultraviolet light source, and method of adjusting laser light source device for extreme ultraviolet light source device
An EUV light source device properly compensates the wave front of laser beam which is changed by heat. A wave front compensator and a sensor are provided in an amplification system which amplifies laser beam. The sensor detects and outputs changes in the angle (direction) of laser beam and the curvature of the wave front thereof. A wave front compensation controller outputs a signal to the wave front compensator based on the measurement results from the sensor. The wave front compensator corrects the wave front of the laser beam to a predetermined wave front according to an instruction from the wave front compensation controller.
US08698112B2 Extreme ultraviolet light generation apparatus
An apparatus, configured to generate extreme ultraviolet light by irradiating a target material by a laser beam from a laser apparatus to turn the target material into plasma, includes a chamber with an inlet for introducing the laser beam into the chamber, the chamber including an electrically conductive structural member; and a target generator including an electrode having a first through-hole through which a charged target passes, an electrical insulator for holding the electrode, and a shielding member having a second through-hole, through which the charged target passes, the shielding member being positioned between a plasma generation region and at least the electrical insulator. The target generator generates the charged target of a liquid target material and output the charged target toward the plasma generation region inside the chamber, and the shielding member has electrically conductive properties and is connected electrically to the electrically conductive structural member of the chamber.
US08698104B2 System and method for handling multiple workpieces for matrix configuration processing
A system for loading workpieces into a process chamber for processing in a matrix configuration includes a conveyor configured to transport multiple workpieces in a linear fashion. A workpiece hotel is configured to receive the multiple workpieces from the conveyor. The workpiece hotel comprises a matrix of cells arranged in N columns and M floors. A pick blade is configured to insert into the hotel and retract from the hotel in order to unload a plurality of substrates from a first floor into a single row of the pick blade, and to repeat the unloading operation to form a matrix comprising a plurality of rows of substrates disposed on the pick blade. In one example, the workpiece hotel has a staggered configuration that provides individual accessibility of each hotel cell.
US08698100B2 System and apparatus for sanitizing a door opening device or other point of contact
An apparatus for sanitizing a point-of-contact surface may include a housing configured to be affixed about at least a portion of said point of contact. The housing may have an interior in or through which the point of contact may be accessed and an anterior opening for access to the interior. The apparatus may further include one or more sources of a sanitizing agent configured to direct the sanitizing agent toward a location where at least a portion of the point-of-contact surface may be disposed. One or more of an anterior dome, an inner surface, and a posterior surface may also be configured to reflect the sanitizing agent toward the location where at least a portion of the point-of-contact surface may be disposed.
US08698099B2 Attraction member, and attraction device and charged particle beam apparatus using the same
A chucking member for holding a target is removably mounted on a chucking stage with a plurality of vacuum holes. the chucking member has a substrate removably mounted on the chucking stage. The substrate has a vacuum region in which the target being to be arranged, the vacuum region allowing gas to be vacuumed through a part of the plurality of the vacuum holes, and a vacuum inhibition region provided around the vacuum region, the vacuum inhibition region covering the other of the vacuum holes to inhibit the gas from being vacuumed through the other of the vacuum holes.
US08698094B1 Permanent magnet lens array
A permanent magnetic lens array for charged-particle focusing includes a first sheet of soft magnetic material, wherein the first sheet of soft magnetic material includes a plurality of snorkel cone protrusions arranged in an array pattern, wherein each snorkel cone is axially symmetric and includes an opening passing from a first surface of the first sheet of soft magnetic material to a second surface of soft magnetic material, and a plurality of permanent magnetic elements, wherein each permanent magnetic element is axially symmetric and arranged concentrically with a snorkel cone of the first sheet of soft magnetic material, wherein the snorkel cones of the first sheet of soft magnetic material and the plurality of permanent magnetic elements are configured to form a plurality of magnetic lenses, wherein each magnetic lens has a magnetic field with an axial component oriented perpendicular to the first surface of the soft magnetic material.
US08698091B2 Semiconductor MOS entrance window for radiation detectors
A semiconductor detector device, such as a PIN diode or silicon drift detector, including a substrate with an entrance window. The entrance window comprises a conductive layer, and an insulating layer disposed between the conductive layer and the substrate. The insulating layer and conductive layer cover a center portion of the surface of the substrate.
US08698090B2 Practical SPECT calibration method for quantification of nuclides with high-energy contributions
When calibrating a nuclear camera, such as a SPECT camera, point spread functions (PSF) are simulated for all possible photon energies and detection distances that the camera may experience. During manufacturer-side calibration, a point source (14) is imaged by the nuclear camera and a PSF therefor is measured. The measured PSF is compared to one or more simulated PSFs and a difference therebetween is determined. To calibrate the measured PSF, simulated PSF data is interpolated into the measured PSF to minimize the difference between the measured and simulated PSFs. The calibrated PSF is stored to memory and accessed during user-side calibration. A user then images a tracer sample during a routine camera calibration, and a PSF for the tracer sample is compared to the calibrated PSF to determine a level of contamination in the tracer sample. The tracer sample PSF is then calibrated for use in reconstructing nuclear images.
US08698086B2 High effective atomic number polymer scintillators for gamma ray spectroscopy
A scintillator material according to one embodiment includes a bismuth-loaded aromatic polymer having an energy resolution at 662 keV of less than about 10%. A scintillator material according to another embodiment includes a bismuth-loaded aromatic polymer having a fluor incorporated therewith and an energy resolution at 662 keV of less than about 10%. Additional systems and methods are also presented.
US08698085B2 Analysis apparatus
An analysis apparatus for analyzing a gas by a terahertz wave or an infrared ray comprises a generator for generating the terahertz wave or the infrared ray; a trapping unit having a trapping film for trapping a gas and being placed to be capable of causing interaction between the gas trapped by the trapping film and the terahertz wave or infrared ray generated by the generator; and a detector for detecting the interaction of the gas with the terahertz wave or infrared ray; wherein the trapping unit comprises a structure for contact with a site evolving the gas; and the structure holds the trapping film separately from the site.
US08698083B2 Solar cell evaluation method, evaluation device, maintenance method, maintenance system, and method of manufacturing solar cell module
A method and device for evaluating a solar cell each of which makes it possible to easily evaluate a defect of a solar cell especially in such a manner that an internal cause defect and an external cause defect are distinguished from each other. The device includes: electric current passing means for passing, in a forward direction, an electric current through a solar cell element constituting the solar cell; light emission detecting means for detecting, out of light emitted from the solar cell element due to the electric current passed by the electric current passing means, light in a first range of wavelengths from 800 nm to 1300 nm and light in a second range of wavelengths from 1400 nm to 1800 nm; and judging means for distinguishing between an internal cause defect and an external cause defect.
US08698082B2 High-fidelity device for single-shot pulse contrast measurement based on quasi-phase-matching (QPM)
A high-fidelity device for single-shot pulse contrast measurement based on quasi-phase-matching includes a generating unit of sampling pulse, a high-fidelity cross-correlation unit of nonlinear SFG and a high-sensitivity signal detecting unit. An innovatively designed dot-mirror or dot-attenuator and correlating crystal. The dot-mirror or dot-attenuator is adopted to suppress the scattering noise, which is mainly induced by air scattering of the main peak of the correlation beam, to a level below the real pulse background. While the crystal is introduced into the device as a nonlinear correlation crystal to move two kinds of artifacts introduced by a correlation process respectively out of the temporal window and behind the main pulse, so that effects of the artifacts on the contrast measurement in a pulse leading edge are removed, without obviously affecting other parameters. The device is also fit for measuring contrasts of high-power lasers of various wavelengths.
US08698081B2 Pattern inspection apparatus and pattern inspection method
The pattern inspection apparatus includes: an irradiator irradiating a sample with an electron beam; an electron detector detecting an amount of electrons generated on the sample having a pattern formed thereon, by the irradiation of the electron beam; an image processor generating a SEM image of the pattern on the basis of the electron amount; and a controller acquiring defect position information on the pattern formed on the sample from an optical defect inspection device. The controller specifies a defect candidate pattern from the SEM image on the basis of the defect position information and judges whether a defect in the defect candidate pattern is to be transferred onto a wafer. The controller determines a view field of the SEM image on the basis of the defect position information and specifies the defect candidate pattern from image information on patterns displayed in the view field.
US08698079B2 Method for scanning electron microscope observation of sample floating on liquid surface
A micro sample floating on the surface of an ionic liquid is observed by scanning electron microscopy without the sample being covered with the ionic liquid. A floating or hydrophobic sample is floated on the surface of a hydrophilic ionic liquid aqueous solution to prevent the micro sample from being covered with the ionic liquid. A hydrophobic ionic liquid is used for hydrophilic samples. With the use of an ionic liquid aqueous solution of low viscosity and large flowability, the micro sample is allowed to freely aggregate, disperse, and align on the surface of the ionic liquid, and to refloat even when settled in the ionic liquid. For easy observation with a scanning electron microscope, the ionic liquid aqueous solution is dried to lower the flowability of the ionic liquid aqueous solution, after the form of the micro sample has stabilized and before electron microscope observation.
US08698078B2 Charged-particle microscopy with occlusion detection
This invention relates to a method of examining a sample using a charged-particle microscope. This invention solves the problem of occlusion effects, whereby a given line-of-sight behind a particular region on a sample and a given detector is blocked by a topographical feature on the sample, thus hampering detection of the emitted radiation emanating from the occluded region. This problem is solved by using at least a first and second detector configuration to detect each portion of the emitted radiation and to produce at least a first and second corresponding image based thereupon; and using computer processing apparatus to automatically compare different members of the set of corresponding images and mathematically identify on the sample at least one occlusion region with an occluded line-of-sight relative to at least one of the detector configurations.
US08698076B2 Differential mobility analyzer, particle measuring system, and particle sorting system
In order to provide a differential mobility analyzer and the like that allows (i) easy increase of an upper limit of particle size of charged particle which can be classified and (ii) analysis of charged particles whose particle size is variable, a DMA (Differential Mobility Analyzer) includes: a classification tank in which an inlet electrode having an inlet slit, an intermediate electrode having a slit, and an outlet electrode having an outlet slit are arranged in sequence in such a manner that adjacent electrodes are disposed opposing each other at predetermined intervals; a gas supply section supplying the classification tank with sheath gas; and a voltage generator applying a predetermined voltage between the electrodes disposed opposing each other, the classification tank including a first classification section and a second classification section each formed by the electrodes disposed opposing each other, and the gas supply section controlling a flow rate of the sheath gas to be supplied to the classification tank individually per first classification section and second classification section.
US08698069B2 Switch
A slit is formed in a plunger of a limit switch in such a manner that an amount of light incident on a light receiving element is changed in accordance with displacement of the plunger. The limit switch is provided with a setting processing unit (123) for setting a voltage value outputted from the light receiving element as a threshold value when a setting instruction is inputted in a state where the plunger is displaced to a designated position by a user, a position detecting unit (113) for performing detection processing of detecting whether or not the plunger is placed at a closer position to a reference position than to the designated position by comparing the set threshold value and the voltage value outputted from the light receiving element, and an output signal controlling unit (119) for outputting a signal based on a result of the detection processing. Thereby, the switch for outputting the signal in accordance with a position of a displacement member, the switch being capable of easily outputting the signal in accordance with a desired position of the displacement member without need for an adjusting screw can be provided.
US08698067B2 System and method for detecting movement of an object and integrated circuit implementation thereof
The present invention relates to a detection system for detecting movement of a movable object. The detection system comprises a light source (S) for emitting light, a reflecting unit (8) being arranged in functional connection with the movable object (6) and being adapted for reflecting the emitted light, at least one detector (D1 to D4) for detecting the reflected light and outputting detection signals for determining the movement of the movable object, an analogue-to-digital converter which includes at least one current source for obtaining a digital signal, and a common mode controller for outputting at least one common mode signal for controlling the at least one current source, wherein the digital signal which is indicative of the movement of the movable object in a predetermined direction being based on the output signal of the at least one detector and the at least one common mode signal. The present invention also concerns a method of detecting movements of a movable object, as well as an integrated circuit having implemented therein the detection system.
US08698066B2 Photodetecting device and display apparatus
Provided is a photodetecting device having a wider dynamic range with a simple configuration. A photodetecting device includes a photodiode (D1) (photodetecting element); a line RST (reset signal line); a line RS (readout signal line); a sensor row driver (5) (signal control section) that outputs, as a reset signal, a pulse signal generating a second voltage (VSS) to the line RST, and outputs a readout signal to the line RS; an accumulation node (11) connected to the line RST via the photodiode (D1), the accumulation node having a potential that varies with an amount of light received by the photodiode (D1) during a sensing period; and a transistor (M1) (sensor switching element) that reads out a signal corresponding to the variation of the potential of the accumulation node (11), and outputs the signal to the output line. The sensor row driver (5) applies a voltage at a level between a first voltage (V_SSR) and the second voltage (VSS) to the line RST, during at least a part of the sensing period.
US08698065B2 Photo sensing module having protection function and display device
A photo sensing module is provided on a first substrate and includes a photo sensing device and a protection wiring. A gap exists between the photo sensing module and an external circuit, and the photo sensing device is provided on the first substrate. The protection wiring is electrically-conductive and located between the external circuit and at least a portion of the photo sensing device.
US08698064B2 Solid-state imaging device
A solid-state imaging device according to the present invention includes pixels which are arranged two-dimensionally and each of which includes: a light absorbing layer that converts light into signal charges; a signal read circuit to read out the signal charges, the signal read circuit being formed on a side opposite to a light incident plane side of the light absorbing layer; a metal layer that is formed on the light incident plane side of the light absorbing layer, the metal layer having an aperture to transmit, into the light absorbing layer, light of a wavelength range depending on a shape of the aperture, a driving circuit that applies a voltage to the metal layer to generate, in the light absorbing layer, a potential gradient to collect the signal charges.
US08698062B2 A/D converter, solid-state image sensor using plurality of A/D converters and driving method of A/D converter for correcting an offset value of the A/D converter based on a held offset value
An analog-to-digital converter converts an analog signal into a digital signal by measuring a time period until a magnitude relation between a voltage level of a reference signal that changes along with time and a voltage level of the analog signal is inverted. The converter comprises a holding unit which holds, as a voltage level that is an analog value, an offset value of the analog-to-digital converter upon analog-to-digital converting a reference voltage level by the analog-to-digital converter, wherein the offset value of the analog-to-digital converter is corrected by changing the voltage level of the analog signal by the voltage level of the offset value held by the holding unit.
US08698060B2 Position detection system, display panel, and display device
Disclosed is a position detection system capable of detecting the position of a line-shaped object. From among two connected lines (E1E2 and E1′E2′) created by connecting opposed intersecting points among four interesting points (E1, E2, E1′, and E2′), a position detection unit (12) treats the one connected line (E1E2) with a length closer to the overall length of a rod (ST) as the position of the rod (ST) that overlaps a coordinate map region (MA).
US08698053B2 Method for producing an electronic device
A method for producing an electronic device is disclosed. One embodiment provides two soldering partners to be connected to one another at an envisaged joining location and at least one of which includes an electronic component or is formed as such a component, a soldering apparatus having an inductor, and an intermediate plate The soldering partners, the inductor and the intermediate plate are positioned in such a way that the intermediate plate is arranged between the electronic component and the envisaged joining location, on the one hand, and the inductor. The soldering partners are connected at the envisaged joining location by using a solder that is melted by energy emitted by the inductor.
US08698051B2 Heating system, heater, and methods of heating a component
A heater includes at least one heating element having a resistance that varies non-linearly with respect to a temperature of the heating element. The heating element includes a first surface, a second surface opposite the first surface, a third surface extending between the first and second surfaces, and a fourth surface extending between the first and second surfaces, opposite the third surface. The heating element has a height defined between the first and second surfaces, and a width defined between the third and fourth surfaces, and wherein the width is less than the height. The heater also includes at least one electrode coupled to the first surface and configured to generate an electric field across the heating element and cause a current to flow through the heating element.
US08698050B2 Dispensing device for heated flowable product
The present invention provides a heating device capable of dispensing heated personal care product while containers thereof are being heated. For example, there could be a base having multiple wells with a heating system associated with each well. There could be separate control of the heat in each well. The wells have an upper opening for permitting insertion of a container in them (in inverted fashion), and a side opening for permitting heated material in a container to be dispensed from the container while a portion of the container is being heated in the well. In another form, the invention provides a temperature sensor at the bottom of a heating well that projects into a heat conductive head of a container being warmed in the well. Methods for using such devices are also disclosed.
US08698047B2 Device for heating a golf ball
The present disclosure relates to a handheld clamp device for applying heat to a golf ball. The clamp may have two lever arms each attached at one end to a pivot. A golf ball receiving unit may be attached to each lever arm at the opposite end as the pivot. Each golf ball receiving unit may include a heating element. The internal heating surface of each golf ball receiving unit may contain a pattern, which can be a dimple pattern. When in use, the handheld device may heat the surface of a golf ball such that the pattern on the internal heating surfaces forms a dimple pattern into the surface of the golf ball. The handheld clamp device may be included as part of a kit, along with multiple sets of golf ball receiving units, and sometimes at least one golf ball.
US08698046B2 Heater and image heating apparatus including same
The image heating apparatus includes a heater that achieves even heat-generation distribution and suppression of a non-sheet feeding portion temperature increase when an image is printed on a sheet whose size is smaller than a maximum size for the apparatus, and an endless belt, wherein plural heat-generation resistive members having positive temperature coefficients are connected in parallel are provided between first and second conductive members provided along a longitudinal direction of a substrate; plural heat-generation blocks including the plural heat-generation resistive members connected in parallel, are arranged in series along the longitudinal direction; and in the plural heat-generation resistive members included in one of the heat-generation blocks, a heat-generation resistive member arranged at an end portion in the longitudinal direction has a resistivity value higher than that of a heat generation resistive member arranged at a center in the longitudinal direction, or an interval between heat generation resistive members is larger in the end portion.
US08698042B2 Cosmetic applicator device including a heater member
A device for applying a composition may include an independent electrical energy source, at least one heater member that is powered by the independent electrical energy source and a circuit for controlling the power supply to the heater member. The circuit may be configured to power the heater member at least two power settings that differ at least as a function of the depletion state of the independent electrical energy source.
US08698041B2 Laser assisted machining apparatus with distributed lasers
Laser assisted machining process and machine utilizing multiple distributed laser units that are strategically distributed around the workpiece being machined to simultaneously heat the workpiece, creating a desired temperature distribution for laser assisted machining. Sequential incremental heating from different directions and positions are used, resulting in longer tool life and shorter machining time.
US08698033B2 Interrupting chamber with a field distributor cylinder for high-voltage or medium-voltage circuit breakers
An insulating tube (18) located between the main contacts (12b, 14b) and the arcing contacts (12a, 14a) of an interrupting chamber (10) of a high-voltage or medium-voltage circuit-breaker makes it possible to modify the distribution of the equipotential lines (V) during breaking. Thus, it is possible to reduce the electric field on the contacts, and thus to improve the breaking and the dielectric strength in the open position. The insulating tube (18) can also serve for transmitting movement between the contacts (12, 14) for triggering the circuit-breaker.
US08698027B2 Pushbutton switch
A pushbutton switch assembly includes a molded housing body with an integral central barrel, a pushbutton mounted in the housing body and having a stem plunger received in and longitudinally movable in the barrel with the operation of the pushbutton and a return spring for returning the pushbutton to a normal position when it is depressed and released. The central barrel and plunger are of a matching non-round shape thereby preventing rotation of the button in relation to the housing.
US08698022B2 Seal structure for switch mechanism and electric power tool
A seal structure for a switch mechanism includes a switch disposed in a housing, an operating member protruding forward from the housing through an opening formed in the housing and configured to turn on or off the switch, a rubber cover attached to the operating member from a front-side of the operating member and having a rear end engageable with the opening, and a fixing cover fixed to the operating member from outside the rubber cover so as to integrate the rubber cover with the operating member. In this seal structure, the rubber cover seals gap between the opening and the operating member.
US08698021B2 Socket structure of micro switch
A socket structure of a micro switch includes a plurality conductive pins of at the bottom of the switch, and a plurality of grooves and distal slots, and the grooves are formed at the bottom of the switch, and the pins are disposed in the grooves, and the distal slots are formed on an outer wall of the switch and interconnected to the grooves respectively, and the top of the pin is extended into the distal slot, so that the pin is exposed from the outer wall of the switch, and the grooves are provided for positioning the pins and preventing them from being deformed, and containing a solder paste for soldering to prevent the switch from being protruded, and the distal slots are provided for extending a soldering iron to touch that pins to facilitate removing and soldering the switch on a surface of a circuit board.
US08698018B2 Key assembly for an electronic device having a connected keycap
The present application provides a key assembly for use in an electronic device. The key assembly comprises a plurality of dome switches and one or more single-piece keycaps. Each keycap has a plurality of key portions separated by deforming portions. The key assembly further comprises a plurality of actuators for activating the dome switches. Each actuator has a stem portion and an enlarged rigid blocking portion. The key assembly also comprises one or more rigid blocking members disposed between the blocking portion of the actuators and the keycaps and in close proximity to the blocking portion of the actuators. The blocking members form a barrier to limit a rotational movement of the actuators away from the dome switches.
US08698017B2 Switch device
In the switch device including the case in which switches are accommodated, tube portions provided on an upper surface of the case, operation knobs swingably provided to the tube portions, operation rods for transmitting movement of the operation knobs to the switches, and the cover covering the upper surface of the case while exposing the operation knobs, projections protruding on the side of the cover are provided on the upper surface of the case, projections protruding on the side of the case are provided on a back surface of the cover, and the projections are arranged in a space between the cover and the case formed when the case is covered by the cover so as to be overlapped with each other when seen from the front and back direction.
US08698016B2 Configuration and method for mounting a key to a deflection web for a keypad
A keypad assembly comprising one or more keys arranged on a deflection web is provided. Each key may comprise a key cap and a post operatively coupled to the key cap. The deflection web may comprise a web having at least one seat configured to receive the post of the key. An adhesive is provided to bond the post to the seat. The post may comprise a plurality of channels and may further comprise a flange for mating with a shoulder of the seat. The channels and the mating flange and shoulder may provide for better glue distribution between the post and the seat. A method for making the keypad assembly is also provided.
US08698015B2 Compensating for multi-touch signal bias drift in touch panels
A system and method provide for selecting a sensor in an array of capacitive sensors, determining a row intensity for the selected sensor, and determining a column intensity for the selected sensor. The system and method may also provide for compensating the selected sensor for multi-touch signal bias drift, wherein the compensating may include adjusting an intensity of the selected sensor based on the row and column intensity.
US08698013B1 Feed weighing insert assembly
A feed weighing assembly includes an assembly scale, a display screen interfacing with the assembly scale and an insert body carried by the assembly scale and sized and configured for placement in a game feeder.
US08698009B2 Printed wiring board and method for manufacturing the same
A wiring board having a penetrating hole formed by forming holes with different shapes from both surfaces of a substrate. In such a penetrating hole, the depth of a first opening portion formed in the first-surface side of the substrate is shallower than the depth of a second opening portion formed in the second-surface side, and the diameter of a first opening is greater than the diameter of a second opening. Even if the gravity line of the first opening portion and the gravity line of the second opening portion are shifted from each other, the region of the second opening portion inserted into the inner space of the first opening portion may be made larger.
US08698008B2 Packaging substrate and fabrication method thereof
A packaging substrate is provided, which includes: a core layer having opposite first and second surfaces; two circuit layers formed on the first and second surfaces, respectively; a plurality of conductive through holes penetrating the core layer and electrically connected to the first and second circuit layers; two insulating protection layers disposed on the first and second surfaces of the core layer and the circuit layers; and a carrier attached to one of the insulating protection layers for preventing cracking of the packaging substrate during transportation or packaging.
US08698001B2 Electrode structure of the touch panel, method thereof and touch panel
An electrode structure is provided. The electrode structure comprises a plurality of first conductive cells and second conductive cells separated from each other and disposed on a substrate; a plurality of first conductive lines connecting adjacent said first conductive cells and a plurality of second conductive lines connecting adjacent said second conductive cells; wherein each said second conductive line comprises a conducting element and a pair of second conductive branches disposed at two sides of said conducting elements and connecting said conducting element to adjacent said second conductive cells; said first conductive lines and said second conductive lines are insulated and intersected. The method of forming an electrode structure is also provided.
US08697995B2 Method and device for coating the junction area between at least two elongated elements, in particular between electric cables
A method of coating the junction area between elongated elements, in particular between electric cables. This method includes the steps of: arranging a rigid tubular support having two axially separable tubular halves; mounting an elastic tubular sleeve in an elastically radially expanded condition on an outer surface of the support; interposing a lubricating material between the support and sleeve; arranging a circumferentially continuous sealing element between the halves to prevent the lubricant from percolating between the halves; positioning the support around the junction area; and moving the halves apart from each other to enable the sleeve to collapse on the junction area. A device for coating the junction area between elongated elements and a method of making the device and a joint for electric cables.
US08697994B2 Wiring holding member, electronic device and image forming apparatus
A wiring holding member includes a holding portion and a wiring holding space. The holding portion is formed in a laying direction of a wiring including a linear wiring and a band-shaped wiring, and holds the band-shaped wiring. The wiring holding space is formed by the band-shaped wiring held in the holding portion, and accommodates the linear wiring therein.
US08697993B2 Hinged busway
A busway section with an electrically conductive housing is described. The busway section includes a lid connected with the housing through a hinging mechanism. Internal slots are also present, along which bus bars can be located. Possible applications of the busway section are feeder sections and plug-in sections.
US08697989B2 Meter box cover
A meter box cover including a first portion that engages an inner surface of an opening in a lid of a meter box to prevent the passage of the cover through the opening and a second portion that extends through the opening and beyond an outermost surface of the opening in the lid of the meter box. The meter cover blocks substantially an entirety of the opening and the second portion prevents the cover from being displaced within the opening.
US08697987B2 Solar cell having front grid metallization that does not contact the active layers
A solar cell has a photovoltaic element having a back electrical contact, and a front current-collection grid cap structure overlying and contacting the photovoltaic solar cell element. The front current-collection grid cap structure is made of a doped semiconductor material and has openings therethrough to the photovoltaic solar cell element. An anti-reflection layer formed of an anti-reflection material overlies and contacts the photovoltaic solar cell element in the openings of the front current-collection grid cap structure. An edge stripe of a cap-top protective material, preferably the same as the anti-reflection material, overlies and contacts each top grid-cap margin of the top cap structure but not a top grid-cap central region of the top cap-structure. A metallic electrical current collector overlies and contacts the top cap structure and at least some of the edge stripe, but does not contact the anti-reflection layer and does not contact the photovoltaic solar cell element.
US08697985B2 Protective film for a solar cell module
The invention relates to a protective film for a solar cell module, to a process for manufacturing said protective film and to a solar cell module comprising said protecting film, and to a method for protecting a solar cell module comprising using of such protective film. The protective film comprises at least one layer comprising a perfluoropolyether (PFPE) polymer [polymer (F)], the polymer being obtainable by cross-linking a composition [composition (C)] comprising: a) at least one functional perfluoropolyether compound [compound (E)], the compound (E) comprising a (per)fluoropolyalkylene chain [chain (Rf)], and at least one unsaturated moiety, the compound (E) being present in an amount included in the range of 10% to 95% wt with respect to composition (C); b) at least one nonfuorinated compound [compound (M)] having at least one unsaturated moiety, provided that the nonfluorinated compound (M) has at least two unsaturated moieties if compound (E) has one unsaturated moiety; and c) at least one crosslinking initiator.
US08697984B2 Resin composition for solar cell encapsulant, solar cell encapsulant and solar cell module using the same
A resin composition for a solar cell encapsulant is provided, containing an ethylene•α-olefin copolymer and an organic peroxide or a silane coupling agent or the like, and having superior heat resistance, transparency, flexibility and adhesion property to a glass substrate, as well as good balance between rigidity and cross-linking efficiency, as well as a solar cell encapsulant, and a solar cell module using the same. The resin composition has an ethylene•α-olefin copolymer (A), having the characteristics (a1) to (a4), along with characteristics (a5) or (a6), and an organic peroxide (B) and/or a silane coupling agent (C).
US08697983B2 Concentrating photovoltaic solar panel
The present invention relates to photovoltaic power systems, photovoltaic concentrator modules, and related methods. In particular, the present invention features concentrator modules having interior points of attachment for an articulating mechanism and/or an articulating mechanism that has a unique arrangement of chassis members so as to isolate bending, etc. from being transferred among the chassis members. The present invention also features adjustable solar panel mounting features and/or mounting features with two or more degrees of freedom. The present invention also features a mechanical fastener for secondary optics in a concentrator module.
US08697980B2 Photovoltaic module utilizing an integrated flex circuit and incorporating a bypass diode
One photovoltaic module has a plurality of photovoltaic cells including a first photovoltaic cell and a second photovoltaic cell, a collector-connector configured to collect a current from the first photovoltaic cell and electrically connect the first photovoltaic cell to the second photovoltaic cell and at least one diode configured to bypass at least one of the photovoltaic cells. Another photovoltaic module has a plurality of cells including a first photovoltaic cell and a second photovoltaic cell, such that the first photovoltaic cell contains an active portion and a shaded portion, that is configured as a diode bypassing the second photovoltaic cell. Methods of making photovoltaic modules that incorporate bypass diodes are also provided.
US08697977B1 Dynamic lighting for musical instrument
This display is a light-emitting display that is capable of creating unique and/or pleasing visual effects. It incorporates a light-emitting diode (LED) display into a sound-generating portion of a sound-generating system. The two are interactive with each other. The idea behind this product line is to create a circuit that “listens” to the music that is being played, and then changes the output state of several lights or LEDs based on the pulses that are being generated by the music. The lights or LEDs would be embedded directly into the musical instrument or speaker cabinet.
US08697972B2 Method and apparatus for computer-mediated timed sight reading with assessment
A music sight-reading apparatus comprises a library of music to be displayed; a display unit for displaying music selected from the library to a user; a timer for displaying the sheet music for a predetermined time period before the user begins sight-reading the displayed music, an input for receiving signals representative of sound produced by the user doing a sight-reading performance of the displayed music; and apparatus for assessing correctness of the user's sight-reading and for preserving a record of the user's sight-reading performance.
US08697970B2 Cymbal mounting assembly
This disclosure relates to cymbal mounting assemblies, and provides viscoelastic washers for mounting a musical cymbal onto a conventional cymbal stand to preserve the integrity of the cymbal.
US08697968B1 Inbred sunflower (Helianthus annuus) line, designated OIN809B
The present invention relates to an inbred sunflower line, designated OIN809B. The invention relates to the seeds of inbred sunflower line OIN809B, to the plants of inbred sunflower line OIN809B and to the methods for producing a sunflower plant, either inbred or hybrid, by crossing the inbred line OIN809B with itself or another sunflower line. The invention further relates to methods for producing a sunflower plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other inbred sunflower lines derived from the inbred OIN809B.
US08697967B1 Inbred corn line SRH55
An inbred corn line, designated SRH55, the plants and seeds of the inbred corn line SRH55, methods for producing a corn plant, either inbred or hybrid, produced by crossing the inbred corn line SRH55 with itself or with another corn plant, and hybrid corn seeds and plants produced by crossing the inbred line SRH55 with another corn line or plant and to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic corn plants produced by that method. This invention also relates to inbred corn lines derived from inbred corn line SRH55, to methods for producing other inbred corn lines derived from inbred corn line SRH55 and to the inbred corn lines derived by the use of those methods.
US08697966B1 Inbred corn line SLM15
An inbred corn line, designated SLM15, the plants and seeds of the inbred corn line SLM15, methods for producing a corn plant, either inbred or hybrid, produced by crossing the inbred corn line SLM15 with itself or with another corn plant, and hybrid corn seeds and plants produced by crossing the inbred line SLM15 with another corn line or plant and to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic corn plants produced by that method. This invention also relates to inbred corn lines derived from inbred corn line SLM15, to methods for producing other inbred corn lines derived from inbred corn line SLM15 and to the inbred corn lines derived by the use of those methods.
US08697965B1 Inbred corn line DES02
An inbred corn line, designated DES02, the plants and seeds of the inbred corn line DES02, methods for producing a corn plant, either inbred or hybrid, produced by crossing the inbred corn line DES02 with itself or with another corn plant, and hybrid corn seeds and plants produced by crossing the inbred line DES02 with another corn line or plant and to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic corn plants produced by that method. This invention also relates to inbred corn lines derived from inbred corn line DES02, to methods for producing other inbred corn lines derived from inbred corn line DES02 and to the inbred corn lines derived by the use of those methods.
US08697964B2 Plants and seeds of corn variety CV720132
According to the invention, there is provided seed and plants of the corn variety designated CV720132. The invention thus relates to the plants, seeds and tissue cultures of the variety CV720132, and to methods for producing a corn plant produced by crossing a corn plant of variety CV720132 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV720132 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV720132.
US08697954B2 Soybean variety A1026431
The invention relates to the soybean variety designated A1026431. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026431. Also provided by the invention are tissue cultures of the soybean variety A1026431 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026431 with itself or another soybean variety and plants produced by such methods.
US08697950B2 Vacuolar pyrophosphatases and uses in plants
The present invention relates to a transgenic plant which is tolerant to a salt, comprising one or more plant cells transformed with exogenous nucleic acid which alters expression of vacuolar pyrophosphatase in the plant. The present invention also relates to a transgenic plant with increased Pi uptake, comprising one or more plant cells transformed with exogenous nucleic acid which alters expression of vacuolar pyrophosphatase in the plant. Also encompassed by the present invention are transgenic progeny and seeds of the transgenic plants described herein. Progeny transgenic plant grown from seed are also described.
US08697944B2 Plants and seeds of hybrid corn variety CH312088
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH312088. The invention thus relates to the plants, seeds and tissue cultures of the variety CH312088, and to methods for producing a corn plant produced by crossing a corn plant of variety CH312088 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH312088.
US08697942B2 Genetic loci associated with Fusarium ear mold resistance in maize
The invention relates to methods and compositions for identifying and selecting maize plants with enhanced resistance to Fusarium ear mold. Maize plants generated by the methods of the invention are also a feature of the invention.
US08697938B2 Disposable absorbent article having side panels with structurally, functionally and visually different regions
A disposable absorbent article worn about the lower torso of a wearer includes at least one pair of side panels connecting a first waist region to a second waist region forming a waist opening and a pair of leg openings. Each side panel includes a waist region, a hip region and a leg region wherein the waist region, the hip region and the leg region differs structurally, functionally and visually to provide an improved initial fit and sustained fit while exhibiting a garment-like appearance.
US08697931B2 Bandaging element of first aid bandage and first aid bandage
A first aid bandage includes bandaging material, a dressing pad and a bandaging element. The dressing pad is attached underneath the bandaging element. The bandaging material is attached to the bandaging element. The bandaging element has been rolled up so that there is a rolled-up portion and a straight portion in the bandaging element. The rolling has been done so that the rolled-up portion can be rolled up over the straight portion, whereby the bandaging element is put in a state of tension. There is an opening arrangement in the rolled-up portion of the bandaging element, in which opening arrangement there are guiding structures. The bandaging material is arranged to fit into the opening arrangement so that a part of the bandaging material is under the guiding structures.
US08697930B2 Conversion of methylamine to olefin or mixture of olefins
Convert a methylamine (e.g. monomethylamine, dimethylamine and trimethylamine) to a mixture of olefins (e.g. ethylene, propylene and butylene) by placing the methylamine, optionally in a mixture with at least one of ammonia and an inert diluent, in contact with a microporous acidic silicoaluminophosphate catalyst or a microporous aluminosilicate catalyst.
US08697929B2 Xylene isomerization process and catalyst therefor
The invention concerns a xylenes isomerization process for the production of equilibrium or near-equilibrium xylenes. The process utilizes a catalyst comprising HZSM-5 or MCM-49 and process conditions including a temperature of less than 295° C. and a pressure sufficient to maintain the xylenes in liquid phase. In embodiments, the process can be operated in a continuous mode with ppm levels of dissolved H2 in the feed and in other embodiments in a cyclic mode without the H2 in feed but with periodic regenerations using a feed having low ppm levels of H2.
US08697926B2 Method for obtaining aromatic hydrocarbons from methane
Process for obtaining aromatic hydrocarbons from a stream containing at least one light hydrocarbon selected from the list comprising methane, ethane, ethylene, propane, propene, propylene, butane, butene or butadiene, which comprises putting said stream into contact with a catalyst, which comprises a catalytic material and a binder, in a fluidized bed reactor. Said reactor may have two reaction zones, an oxidizing zone and a reducing zone.
US08697924B2 Liquid fuel compositions
Liquid fuel compositions comprising one or more C4+ compounds derived from a water soluble oxygenated hydrocarbon.
US08697920B2 Use of solids based on zinc ferrite in a process for deep desulphurizing oxygen-containing feeds
The invention concerns a process for desulphurizing a feed comprising oxygen-containing compounds, hydrocarbon-containing compounds and organic sulphur-containing compounds, by capturing sulphur on a capture mass comprising iron oxides or zinc oxides and more than 20% by weight of zinc ferrite. The process is operated in the presence of hydrogen at a temperature in the range 200° C. to 400° C.
US08697914B2 Process for preparing bis(para-aminocyclohexyl)methane
Process for preparing bis(para-amino-cyclohexyl)methane by multiphase reaction of methylenedianiline with hydrogen, in which the reaction is performed in 5 to 50 series-connected reaction zones under adiabatic conditions.
US08697912B2 N-(1-hydroxyethyl) carboxamide compound and process for producing same
The present invention relates to an N-(1-hydroxyethyl)carboxamide compound represented by formula (1) (in the formula, RA and RB represent independently from each other a hydrogen atom or an alkyl group having 1 to 4 carbon atoms except for a case where RA and RB represent a hydrogen atom at the same time) and a method for producing the same; a method for producing an N-(1-alkoxyethyl)carboxamide compound; a method for producing an N-vinyl carboxylic acid amide compound; and a method for producing an N-vinyl carboxylic acid amide (co)polymer. An N-(1-alkoxyethyl)carboxamide compound can be obtained by reacting N-(1-hydroxyethyl)carboxamide compound with alcohol in the presence of an acid catalyst, and an N-vinyl carboxylic acid amide compound, which is a monomer of the N-vinyl carboxylic acid amide (co)polymer, can be obtained by thermally decomposing or catalytically decomposing the N-(1-alkoxyethyl)carboxamide compound.
US08697910B2 Optically active quaternary ammonium salt having axial asymmetry and process for producing α-amino acid and derivative thereof with the same
The present invention provides a compound of the following formula (I) below. This compound (I) can be produced by reacting a 2,2′-dimethylene bromide-1,1′-binaphthyl derivative, which can be produced by a relatively small number of processes, with an easily available secondary amine. This compound (I) is useful as a chiral phase-transfer catalyst.
US08697907B2 Process for the production of acetic acid
Process for producing acetic acid by carbonylating methanol and/or a reactive derivative thereof in a liquid reaction composition in which there exists in equilibrium, at least a first soluble catalytic species and a second soluble catalytic species. The first catalytic species is the least catalytically active or promotionally active of the species existing in the equilibrium. The process includes determining (i) the concentration of the first catalytic species and/or (ii) the ratio of the concentration of the first catalytic species to the concentration of the second catalytic species in equilibrium therewith, present in the liquid reaction composition and/or a present in a liquid fraction in a separation step, and maintaining (i) and/or (ii) below a pre-determined value.
US08697905B2 Process for producing terephthalic acid
Methods of producing terephthalic acid are described. The methods involve using a p-xylene stream enriched with p-toluic acid. The p-xylene stream enriched with p-toluic acid, a solvent comprising an ionic liquid and optionally a carboxylic acid, a bromine source, a catalyst, and an oxidizing agent are contacted to produce a product comprising terephthalic acid.
US08697904B2 Transition metal-containing catalysts and processes for their preparation and use as oxidation and dehydrogenation catalysts
This invention relates to the field of heterogeneous catalysis, and more particularly to catalysts including carbon supports having formed thereon compositions which comprise a transition metal in combination with nitrogen and/or carbon. The invention further relates to the fields of catalytic oxidation and dehydrogenation reactions, including the preparation of secondary amines by the catalytic oxidation of tertiary amines and the preparation of carboxylic acids by the catalytic dehydrogenation of alcohols.
US08697902B2 Preparation of nitriles from ethylenically unsaturated compounds
A process for the hydrocyanation of a hydrocarbon-based compound having at least one site of ethylenic unsaturation into a nitrile compound includes reaction thereof, in a liquid medium, with hydrogen cyanide in the presence of a catalyst containing a metal element selected from among the transition metals and an organophosphorus ligand, wherein the organophosphorus ligand is a compound of formula (I): The subject process is particularly useful for the synthesis of adiponitrile from butadiene.
US08697897B2 Method for preparing fatty acyl amido carboxylic acid based surfactants
A process is provided for preparing C8-C22 acyl glycinate acid or salt thereof via reacting and heating a mixture of glycine or salt thereof with a C1-C3 alkyl ester of a C8-C22 fatty acid in a medium of glycerol or propylene glycol. The reaction proceeds well where the mixture is formulated to have a pKa ranging from 9.5 to 13.
US08697888B2 Substituted (1-(methylsulfonyl)azetidin-3-yl)(heterocycloalkyl)methanone analogs as antagonists of muscarinic acetylcholine M1 receptors
In one aspect, the invention relates to substituted (1-(methylsulfonyl)azetidin-3-yl)(heterocycloalkyl)methanone analogs, derivatives thereof, and related compounds, which are useful as antagonists of the muscarinic acetylcholine receptor M1 (mAChR M1); synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US08697885B2 Carbazole compound, light-emitting element material, organic semiconductor material, light-emitting element, light emitting device, lighting device, and electronic device
An object is to provide a novel carbazole compound that can be used for a transport layer, a host material, or a light-emitting material in a light-emitting element. A carbazole compound where nitrogen of a carbazole group, the carbazole skeleton of which whose 3-position is bonded to the 4-position of a dibenzofuran skeleton or a dibenzothiophene skeleton, is bonded to a benzimidazole skeleton through a phenylene group, is provided. The carbazole compound has a high carrier-transport property, and can be suitably used for a material for a light-emitting element or for an organic semiconductor material.
US08697884B2 Method of manufacturing cyclic carbonate by using ionic liquid polymer
A method of manufacturing cyclic carbonate comprises a step of “preparation,” by preparing an ionic liquid polymer; and a step of “cyclization,” by feeding carbon dioxide and epoxide into a reactor containing the ionic liquid polymer to conduct a cyclization of the carbon dioxide and the epoxide in a batch or continuous reaction manner under the catalysis of the ionic liquid polymer, and finally to produce cyclic carbonate.
US08697883B2 Cyclopenta[C]pyrrole-2-carboxylate derivatives, preparation thereof and therapeutic use thereof
The invention relates to cyclopenta[c]pyrrole-2-carboxylate derivatives, to their preparation and to their therapeutic use.
US08697882B2 Compound, resin and photoresist composition
The present invention provides a compound represented by the formula (I): wherein R1 represents a hydrogen atom, a halogen atom or a C1-C6 alkyl group which may have one or more halogen atoms, A1 represents a divalent connecting group, X1 represents a C2-C36 heterocyclic group and one or more —CH2— in the C2-C36 heterocyclic group can be replaced by —CO— or —O—, R2 is independently in each occurrence a halogen atom, a hydroxyl group, a C1-C24 hydrocarbon group, a C1-C12 alkoxy group, a C2-C4 acyl group or a C2-C4 acyloxy group, and m represents an integer of 0 to 10.
US08697880B2 Compounds useful for the synthesis of S- and R-omeprazole and a process for their preparation
The present invention relates to an improved method for the synthesis of the (S)- or (R)-enantiomer of omeprazole, characterized in that 2-[[(4-X-3,5-dimethylpyridin-2-yl)methyl]thio]-5-methoxy-1H-benzimidazole or 2-[[(4-X-3,5-dimethyl-1-oxidopyridin-2-yl)methyl]thio]-5-methoxy-1H-benzimidazole, wherein X is a leaving group, is oxidized into the corresponding sulphoxide which is obtained as a crystalline compound. Recrystallization of the thus obtained sulphoxide results in a compound of enhanced chemical and optical purity, which is subsequently transformed into the (S)- or (R)-enantiomer of omeprazole.
US08697875B2 Phosphodiesterase inhibitors and uses thereof
The invention provides for compounds that are phosphodiesterase inhibitors. The invention further provides for a method for screening compounds that bind to and modulate a phosphosdiesterase protein. The invention also provides methods for treating conditions associated with accumulated amyloid-beta peptide deposit accumulations by administering a phosphodiesterase-binding compound to a subject.
US08697873B2 Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
Imidazopyridine, imidazoquinoline, and imidazonaphthyridine compounds having an amide substituent at the 1-position, pharmaceutical compositions containing the compounds, intermediates, and methods of making and methods of use of these compounds as immunomodulators, for modulating cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
US08697868B2 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
Disclosed are substituted xanthines of the formula wherein R is defined as in claim 1, the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, which have valuable pharmacological properties, particularly an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).
US08697867B2 Cross-linked cyclic amine compounds and agents for pest control
Cyclic amine compounds represented by formula (1) or salts thereof or N-oxides thereof, wherein Cy1 represents an unsubstituted or substituted aromatic ring; X represents oxygen, sulfur, unsubstituted or substituted nitrogen, sulfinyl, or sulfonyl; R1a and R2a, R1a and R4a, R2a and R3a, or R3a and R4a form saturated rings together; R1a, R1b, R2a, R2b, R3a, R3b, R4a, R4b, and R5 which do not form the saturated rings are each independently hydrogen, hydroxyl, halogen, unsubstituted or substituted amino, nitro, or an organic group; Cy2 represents an unsubstituted or substituted aromatic ring with a proviso that Cy2 is an unsubstituted or substituted heteroaromatic ring when R1a and R2a form a saturated ring together and Cy1 is an unsubstituted or substituted phenyl, and Cy2 is a substituted pyridin-2-yl having one or more cyano as a substituent when Cy1 is an unsubstituted or substituted phenyl and Cy2 is a pyridin-2-yl.
US08697860B1 Diagnosis and treatment of disease
Provided herein are methods, compounds, and compositions for reducing expression of transthyretin mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate transthyretin amyloidosis, or a symptom thereof.
US08697857B2 Soybean EF1A2 promoter and its use in constitutive expression of transgenic genes in plants
The promoter of a soybean translation elongation factor EF1 alpha, a polypeptide that promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis, and fragments thereof and their use in promoting the expression of one or more heterologous nucleic acid fragments in a tissue-independent or constitutive manner in plants are described.
US08697856B2 Plasmodium vivax hybrid circumsporozoite protein and vaccine
Described in this application is a synthetic P. vivax circumsporozoite protein useful as a diagnostic reagent, for antibody production, and as a vaccine protective against infection with any strain of P. vivax.
US08697855B2 Anti-CD151 antibodies and their use in the treatment of cancer
The present invention relates to new antibodies capable of binding specifically to the human CD151 protein, especially monoclonal antibodies of murine origin, which are chimeric and humanized, and also to the amino acid and nucleic sequences coding for those antibodies. The invention also includes use of those antibodies as medicaments for the prophylactic and/or therapeutic treatment of cancers and in diagnostic methods or kits for diseases associated with overexpression of the CD151 protein. Finally, the invention includes products and/or compositions comprising such antibodies in association with antibodies and/or anti-cancer agents or conjugated with toxins and/or radioelements and their use in the prevention and/or treatment of certain cancers.
US08697854B2 High affinity T cell receptor and use thereof
The present invention is directed to a high affinity T cell receptor (TCR) against a tumor-associated antigen, an isolated nucleic acid molecule encoding same, a T cell expressing said TCR, and a pharmaceutical composition for use in the treatment of diseases involving malignant cells expressing said tumor-associated antigen.
US08697851B2 MiRNA-regulated differentiation-dependent self-deleting cassette
Targeting constructs and methods of using them are provided for differentiation-dependent modification of nucleic acid sequences in cells and in non-human animals. Targeting constructs comprising a promoter operably linked to a recombinase are provided, wherein the promoter drives transcription of the recombinase in an differentiated cell but not an undifferentiated cell. Promoters include Blimp1, Prm1, Gata6, Gata4, Igf2, Lhx2, Lhx5, and Pax3. Targeting constructs with a cassette flanked on both sides by recombinase sites can be removed using a recombinase gene operably linked to a 3′-UTR that comprises a recognition site for an miRNA that is transcribed in undifferentiated cells but not in differentiated cells. The constructs may be included in targeting vectors, and can be used to automatically modify or excise a selection cassette from an ES cell, a non-human embryo, or a non-human animal.
US08697846B2 Methods of making monoclonal antibodies using fusion-peptide epitope adoptive transfer (F-PEAT) technology
Disclosed are compositions and methods for related to monoclonal antibodies specific for single amino acid variation in an antigen.
US08697843B1 Superabsorbant materials from chemically modified gluten
The present disclosure provides superabsorbent materials comprising wheat gluten chemically modified with citric acid, methods of producing superabsorbent materials and methods of use.
US08697837B2 Substrate for Rpn 11 enzymatic activity
The present application provides peptides that serve as substrates for proteasome enzymatic activity, e.g., the enzymatic activity of Rpn11, a metalloprotease of the 19S regulatory particle. The present application also provides methods and compositions employing the peptide substrates.
US08697836B2 Composition and method for inducing and enhancing a telomerase reverse transcriptase-reactive cytotoxic T lymphocyte response
Telomerase peptides that bind MHC are disclosed. The instant application also discloses vaccines containing said peptides and methods of using said peptides to enhance a CTL response against mammalian cancer cells.
US08697828B2 Hydrosilicone resin and preparation process thereof
The present invention relates to a liquid hydrosilicone resin and a preparation process thereof. The average composition of the liquid hydrosilicone resin is represented by the following formula: (R1R2R3SiO1/2)M.(R4R5SiO2/2)D. (R6SiO3/2)T.(SiO4/2)Q wherein R1 to R6 are identical or different radicals independently selected from the group consisting of organic groups and a hydrogen atom, with the proviso that at least one of R1to R6 is a hydrogen atom bonded directly to a silicon atom.The liquid hydrosilicone resin is obtained by dispersing a hydrosilicone oil, a hydroxyl silicone resin and a dehydrogenation catalyst in a solvent to form a dispersion, allowing the dispersion to react, and then removing the solvent and the catalyst.
US08697826B2 Self-crosslinkable latex polymer and method for making the same
A self-crosslinkable latex polymer includes: a polymer chain having a plurality of ethylenically unsaturated units; and a plurality of peroxide functional groups bonded to the polymer chain and having a structure represented by —R1—C—O—O—R2 or —R4—(COO)—C—O—O—R5, wherein R1 and R4 each represents a hydrocarbon group and is bonded to the polymer chain and R2 and R5 each represents hydrogen or an alkyl group having 1 to 12 carbon atoms.
US08697823B2 Catalysis of cross-linking
Disclosed is use of catalysts for chain extension and/or cross-linking of oligomers or polymers comprising carbon-carbon triple bonds.
US08697822B2 Polymerization of fluoropolymers using non-fluorinated surfactants
The present invention relates to a method for the polymerization in an aqueous medium of monomers, and especially of fluoromonomers, using non-fluorinated surfactants; and the fluoropolymers formed therefrom. Specifically, the method of the polymerization uses one or more non-fluorinated surfactants selected from the group consisting of polyvinylphosphonic acid, polyacrylic acids, polyvinyl sulfonic acid, and salts thereof. Additionally, the use of polyvinylphosphonic acid, polyacrylic acids, polyvinyl sulfonic acid as surfactants in aqueous free radical polymerization is also novel.
US08697800B2 Silane cross-linked 1-component lamination adhesive
The invention relates to a crosslinkable one-component lamination adhesive containing a) 25 to 80 wt % of polyester prepolymers, polyether prepolymers, and/or polyurethane prepolymers that comprise at least two crosslinkable silane groups, b) 75 to 20 wt % organic solvent having a boiling point of up to 130° C., c) 0 to 15 wt % additives, the prepolymer having a molecular weight from 2000 to 30,000 g/mol, wherein the viscosity of the adhesive is between 50 and 20,000 mPas (per DIN ISO 2555) measured at 15 to 45° C., and the crosslinked adhesive has a glass transition temperature from −10 to 30° C.
US08697799B2 Non-aqueous, liquid coating compositions
Non-aqueous, liquid coating compositions which contain at least one polyurethane resin B with blocked isocyanate groups and at least one binder C with functional groups reactive towards the blocked isocyanate groups of B, wherein the at least one polyurethane resin B is present as particles having a melting temperature of 40 to 160° C.
US08697798B2 Silicone rubber composition for use as high-voltage insulator and polymer insulator
A silicone rubber composition comprising (A) an organopolysiloxane composition of the organic peroxide cure or addition reaction cure type, (B) a normally solid organic compound having at least two ester bonds per molecule, and (C) particulate aluminum hydroxide having an average particle size of up to 20 μm is suited for use as high-voltage electric insulator since it maintains insulating properties for a long term in outdoor service and has acid resistance and a long lifetime even in polluted areas.
US08697795B2 Thermoplastic linoleum
The present invention relates to a thermoplastic molding composition at least comprising particles made of nonoxidatively polymerized vegetable oil which has been crosslinked by way of functional groups, as component (A), at least one thermoplastic polymer, as component (B), optionally at least one resin, as component (C), optionally at least one filler, as component (D), and optionally further additives, use thereof and a process for production thereof.
US08697794B2 Impact modified styrenic polymers with improved stress crack properties
A method of improving the stress crack resistance of an impact modified styrenic polymer comprising (a) combining about 95 to about 99.5 wt. % of an impact modified styrenic polymer with about 0.5 to about 5 wt. % of a polymer solution comprising about 25 to about 75 wt. % polyisobutylene and about 25 to about 75 wt. % of a polyolefin comprising one or more C2 to C12 alpha olefins.
US08697791B2 Optical material and optical element
An optical material including a polymer of a mixture which contains a sulfur-containing compound, a fluorene compound with a fluorene skeleton, and an energy polymerization initiator. The sulfur-containing compound contains, in a molecule, at least one kind of group selected from the group consisting of a sulfide group, a sulphone group, a sulfoxide group, a thiol group, and a thioester group. A refractive index of the polymer of the mixture is 1.65 or more to less than 1.92, an Abbe constant thereof is 15 or more to less than 22, and a difference Δθg,F between a secondary dispersion property θg,F thereof and a secondary dispersion property θg,F of a normal optical material which is expressed by θg,F=0.6438−0.001682νd is 0.05 or more to less than 0.13.
US08697786B2 Flame-retardant compound, continuous materials and products constructed therefrom and methods of manufacture thereof
A zero-halogen flame-retardant compound and continuous materials extruded therefrom comprise poly(ethylene terephthalate) (PET), fire-retardant ingredients melamine cyanurate (MC) and melamine polyphosphate (MPP), and an organo titanate coupling agent. The coupling agent acts as a dispersion agent to the fine powders of PET, MC and MPP and also allows the resin of the fine powders to be compounded at a reduced temperature which prevents degradation of the PET. The compound can be extruded as a thin film, sheet or tubing, and also as a filament or yarn, including monofilaments and multifilaments, which can ultimately be used to construct a protective sleeve.
US08697780B2 High strength concrete made with PVA reinforcement fibers and its associated method of manufacture
An improved concrete mix composition and its associated method of manufacture. A traditional concrete mix is created by mixing cementitious material with sand, aggregate, admixture chemicals and water. After the traditional mix has been thoroughly mixed, reinforcement fibers of polyvinyl alcohol are added to the mix. The reinforcement fibers chemically bond to the cementitious material, thereby chemically integrating the reinforcement fibers into the mixture. The reinforcement fibers are supplied in multiple sizes. The reinforcement fibers include both long thick fibers and short thin fibers. In this manner, the smaller reinforcement fibers can fill voids around the larger, thicker reinforcement fibers. This helps prevent the development of stress cracks in the concrete and significantly increases the strength, durability, and life expectancy of the concrete.
US08697777B2 Masterbatch for preparing plastic films with high ethylene permselectivity and the plastic films produced therefrom
The invention relates to plastic compounds for preparing films in a masterbatch containing zeolite with surfaces modified by silylation reaction. The films can be obtained through thermoplastic processing by blending the masterbatch with polymers such as polyolefins and polystyrene. The masterbatch includes styrene-b-(ethylene-ran-butylene)-b-styrene copolymers with styrene to ethylene-ran-butylene content of 12:88 to 14:86, and zeolites surfaces modified by silylation reaction with organosilane compound, in 30% to 70% by weight of copolymer with zeolite. The organosilane formula is R1nSiR2R3-n, where R is methoxy, ethoxy or chloro group, R1 is methyl group, R2 is functional group capable of a forming π-π interaction from phenyl, phenylethyl, vinyl, or propyl methacrylate groups, and n is 0 and 2. The films provide higher ethylene transmission and selectivity than films of pure polymers with unmodified zeolite, and can be used for packaging to retard ripening of fresh produce, in particular, ethylene-sensitive commodities.
US08697776B2 Chemical-resistant metallic effect pigments, method for producing the same and use thereof
The invention relates to metallic effect pigments having a plateletlike metal core and, surrounding the plateletlike metal core, a homogeneous synthetic resin coating, the synthetic resin coating comprising polyacrylate and/or polymethacrylate and also organofunctional silane. The invention further relates to a process for preparing such metallic effect pigments, and to their use.
US08697772B2 Polymerizable phosphoric acid derivatives comprising a polyalicylic structure element
Certain novel polymerizable phosphoric acid derivatives (hereinafter referred to as monomers) comprising a polyalicyclic structure element, mixtures comprising one or a plurality of these compounds and corresponding curable blends and products as well as their respective use as a dental material or for the preparation of a dental material are described. The compounds are eminently suitable as bonding agents, in particular in dental adhesive materials. A process for preparing these compounds or mixtures and a method for preparing a product, preferably a product suitable for dentistry, are also described.
US08697768B2 Energy curable overprint varnish and coated product
An energy curable coating composition is provided for use as an overprint varnish on cellulosic, polymeric and metal substrates. The coating composition includes an epoxy acrylate, a triacrylate, and optionally, a diacrylate. The coating composition is applied to a substrate and cured by radiation to form a thermoformable protective coating. The coated substrate may then be thermoformed into a shaped food package or article.
US08697767B2 Production method for pressure-sensitive adhesive composition
Provided is a production method for a pressure-sensitive adhesive composition capable of sufficiently expressing each of “attachment position correction workability” that enables a pressure-sensitive adhesive tape containing the composition to be easily aligned by the expression of good temporary attachment property, “reworkability” that enables the tape to be easily reattached, and “temperature-sensitive strong pressure-sensitive adhesiveness” that enables the tape to express strong temperature-sensitive pressure-sensitive adhesiveness. The production method for a pressure-sensitive adhesive composition is a production method for a pressure-sensitive adhesive composition containing a cross-linked polymer in which an acrylic copolymer (A) is cross-linked by a polyurethane(meth)acrylate (B), the method including irradiating a monomer mixed liquid essentially containing a (meth)acrylate and a (meth)acrylamide with an active energy ray in the presence of the polyurethane(meth)acrylate (B).
US08697765B2 Porous carbon-heteroatom-silicon hybrid inorganic/organic materials for chromatographic separations and process for the preparation thereof
The present invention provides porous carbon-heteroatom-silicon inorganic/organic homogenous copolymeric hybrid materials, methods for their preparation, and uses thereof, e.g., as chromatographic separations materials.
US08697764B2 Elastic inorganic-organic hybrid foam
A process for producing an elastic silicate foam by foaming a mixture comprising 10% to 80% by weight of an aqueous dispersion of SiO2 particles A) which have an average particle diameter in the range from 1 to 100 nm, 5% to 30% by weight of a polymer B) in solution in water, 10% to 50% by weight of a blowing agent C), 1% to 5% by weight of an emulsifier D), 0.01% to 5% by weight of a crosslinker E) which is reactive with the polymer B), and also the foam obtainable by the process, and the use of the foam.
US08697762B2 Silica filler pretreated with bio-based polyol and elastomer composition containing the same
A method includes mixing a filler including silica and a bio-based oil including a soy polyol to form a filler mixture, and mixing the filler mixture with an elastomer to form an elastomeric composition. The weight ratio of silica to the soy polyol is 1.5 to 2.5. The elastomer is present in an amount less than 25 weight percent of the elastomeric composition.
US08697758B2 Urea compound, self-assembly of urea compounds, organogel containing self-assembly, and method for producing organogel
A urea compound of the present invention is represented by general formula (I) shown below: wherein each of X1, X2 and X3 independently represents a hydrogen atom, an alkyl group or an aryl group. The aryl group may have one or more functional groups selected from the group consisting of halogen groups, alkyl groups and alkoxy groups.
US08697757B2 Hydrophobic organic solvent-dispersed sol of anhydrous zinc antimonate colloidal particles and method for producing the same
A hydrophobic organic solvent-dispersed sol of anhydrous zinc antimonate colloidal particles and a method for producing the same. The hydrophobic organic solvent-dispersed sol includes surface-modified anhydrous zinc antimonate colloidal particles dispersed in a hydrophobic organic solvent having a water solubility of 0.002 to 12% by mass. The surface-modified anhydrous zinc antimonate colloidal particles are formed by: coating outer surfaces of anhydrous zinc antimonate colloidal particles (A) serving as cores with at least one substance (B) of colloidal particles of a composite oxide containing silica and stannic oxide or silica and antimony pentoxide at a silica/stannic oxide or silica/antimony pentoxide ratio of 0.1 to 10, an oligomer of the colloidal particles, or a mixture of the colloidal particles and the oligomer to form modified anhydrous zinc antimonate colloidal particles (C); and bonding an organosilicon compound and an amine compound to surfaces of the colloidal particles (C).
US08697756B2 Dimer diol compositions as substitutes of body fluids
The invention relates to compositions containing at least 90% by weight of dimer diol for use in a method for the surgical or therapeutic treatment of the human or animal body, and in particular to the use thereof as a body fluid replacement substance.
US08697753B1 Method of treating onychomycosis
The present invention is directed to a nail lacquer consisting essentially of terbinafine as an antimycotic agent, hydroxypropyl chitosan as film forming agent, water and a lower alkanol as solvents. The invention is also directed to a method for treating onychomycosis by topically administering such a nail lacquer to a patient in need of such a treatment.
US08697747B2 Enhancing coagulation or reducing fibrinolysis
Methods for controlling bleeding (e.g., enhancing coagulation and reducing fibrinolysis) in a subject are disclosed. The methods include selecting a subject in need of enhanced coagulation or reduced fibrinolysis, and administering to the subject a carbon monoxide releasing molecule (CORM). Examples of CORMs include tricarbonyldichloro-ruthenium (II) dimer, tricarbonylchloro-(glycinato)ruthenium (II), sodium boranocarbonate, dimanganese decacarbonyl, and iron pentacarbonyl. Further disclosed are compositions and methods for treating a subject in need of a blood product by administering to the subject a composition including a CORM and a blood product (e.g., cryoprecipitate or fresh frozen plasma).
US08697742B2 BCRP/ABCG2 inhibitor
A breast cancer resistance protein (BCRP/ABCG2) inhibitor. The BCRP inhibitor contains, as an active ingredient, an acrylonitrile derivative or a salt thereof.
US08697738B2 Alpha-aminoamide derivatives useful in the treatment of addictive disorders
Methods of using certain α-aminoamide derivatives in the treatment of RLS and addictive disorders, The compounds of this invention are able to reduce or even stop the symptoms of RLS and addictive disorders substantially without side effects.
US08697737B2 Raf modulators and methods of use
The present invention relates to compounds of the Formula I, wherein G, A, X1, X2, X3, Z, E, Y, and X are defined herein. The compounds modulate protein kinase enzymatic activity to modulate cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases, particularly Raf. Methods of using and preparing the compounds, and pharmaceutical compositions thereof, to treat kinase-dependent diseases and conditions are also an aspect of the invention.
US08697736B2 1H-benzimidazole-4-carboxamides substituted with phenyl at the 2-position are potent PARP inhibitors
Compound having formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds having formula (I), methods of treatment comprising compounds having formula (I), and methods of inhibiting the PARP enzyme comprising compounds having formula (I).
US08697734B2 Method for controlling particular insect pests by applying anthranilamide compounds
This invention pertains to a method for controlling lepidopteran, homopteran, hemipteran, thysanopteran and coleopteran insect pests comprising contacting the insects or their environment with an arthropodicidally effective amount of a compound of Formula I, its N-oxide or an agriculturally suitable salt thereof wherein A and B and R1 through R8 are as defined in the disclosure. This invention further relates to a benzoxazinone compound of Formula 10 wherein R4 through R8 are as defined in the disclosure, useful for preparation of a compound of Formula I.
US08697732B2 Pyridine derivatives
The invention relates to novel pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
US08697723B2 2,3-dihydrobenzo(1,4) dioxin-2-ylmethyl derivatives as alpha2C antagonists for use in the treatment of peripheric and central nervous system diseases
Compounds of formula I wherein X, Z, R1-R4, and m are as defined in the claims, exhibit alpha2C antagonistic activity, and are thus useful as alpha2C antagonists. Methods for the treatment of diseases and conditions of the peripheric system and the central nervous system are also disclosed.
US08697722B2 Nicotinic acetylcholine receptor modulators
The disclosure provides compounds capable of selectively or non-selectively modulating nicotinic acetylcholine receptors. The compounds, compositions, and methods described herein are useful, for example, in treating patients suffering from various medical conditions including pain, chemical addictions, Parkinson's disease, Alzheimer's disease, and neurodegenerative disorders. In one embodiment, the compounds comprise a 7- to 11-membered azabicyclo ring.
US08697720B2 Substituted phenylether-thienopyridone compounds with antibacterial activity
Novel bicyclic heteroaromatic compounds are provided that are inhibitors of bacterial methionyl tRNA synthetase (MetRS). Compounds of the invention generally have a left hand side phenylether constituent and a right hand side thienopyridone constituent. Also disclosed are methods for their preparation and their use in therapy as antibacterial agents, particularly as anti-Clostridium difficile agents.
US08697719B2 Anhydrate of tiotropium bromide
Novel Anhydrate The present invention relates to a novel form of anhydrous tiotropium bromide, processes for the preparation of anhydrous tiotropium bromide, pharmaceutical compositions comprising anhydrous tiotropium bromide and uses of the compositions.
US08697717B2 Inhibitors of histone deacetylase
This invention comprises the novel compounds of formula (I) wherein n, R1, R2, R3, R4, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
US08697715B2 Serine/threonine kinase inhibitors
Compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of hyperproliferative, pain and inflammatory diseases. Methods of using compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
US08697713B2 Pyrrolopyrimidines for pharmaceutical compositions
The present invention relates to novel pyrrolopyrimidine compounds of the general formula (1) and pharmaceutical compositions comprising said pyrrolopyrimidine compounds. Moreover, the present invention relates to the use of the pyrrolopyrimidine compounds of the invention for the production of pharmaceutical compositions for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof.
US08697711B2 Inhibitors of bruton'S tyrosine kinase
Disclosed herein are compounds, including compounds having the structure of Formula (A), (B), (C), and (D), as described in further detail herein, that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
US08697709B2 Fused ring heteroaryl kinase inhibitors
Provided herein are fused ring heteroaryl compounds useful in a variety of methods, including reducing the activity of certain kinases and treating certain disease states.
US08697708B2 Azabenzothiazole compounds, compositions and methods of use
Provided are compounds of Formula I, stereoisomers, tautomers, solvates, prodrugs and pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, R4 and R5 are defined herein, a pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, methods of using the compound or composition in therapy, and methods of manufacturing a compound of Formula I.
US08697707B2 Mixtures of mesoionic pesticides
Disclosed are compositions comprising (a) at least one compound selected from compounds of Formula 1, N-oxides, and salt thereof, wherein R1 is phenyl optionally substituted with up to 5 substituents independently selected from R3, or pyridinyl optionally substituted with up to 4 substituents independently selected from R3; R2 is C1-C4 haloalkyl; or thiazolyl, pyridinyl or pyrimidinyl, each optionally substituted with up to 2 substituents independently selected from the group consisting of halogen and C1-C4 alkyl; each R3 is independently halogen, cyano, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkoxy, C1-C4 haloalkoxy, C(R4)═NOR4 or Q; each R4 is independently C1-C4 alkyl; Z is CH═CH or S; and each Q is independently phenyl or pyridinyl, each optionally substituted with up to 3 substituents independently selected from the group consisting of halogen, cyano, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkoxy and C1-C4 haloalkoxy; and (b) at least one invertebrate pest control agent. Also disclosed are methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a composition of the invention.
US08697704B2 Hepatitis C virus inhibitors
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
US08697702B2 Method of optimizing the treatment of Philadelphia-positive leukemia with imatinib mesylate
The present invention relates to a method of treating Philadelphia-positive leukemia (Ph+ leukemia), in a particular chronic myeloid leukemia (CML), in a human patient population. More specifically, the present invention pertains to a method of treating Ph+ leukemia, such as CML or Phi+ ALL, in a human patient suffering from Ph+ leukemia comprising the steps of (a) administering a predetermined fixed amount of Imatinib as a free base or in the form of a pharmaceutically acceptable salt thereof to the human patient, (b) collecting at least one blood sample from the patient, e.g. within the first 12 months of treatment, (c) determining the plasma trough level (Cmin) of Imatinib, (d) determining the OCT-1 Activity in the blood sample, and (e) adjusting the dose of Imatinib applied to the individual patient in a manner that an Imatinib Cmin value is achieved in the patient of at least 800 ng/mL, if in step (c) an Imatinib Cmin value of less than 800 ng/mL is found and in step (d) an OCT-1 Activity is found below 6.0 to 10.0 ng/200,000 cells.
US08697700B2 Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof
The present invention relates to piperazinone-substituted tetrahydrocarboline derivatives of formula (I): having the substituents as described herein which are melanin-concentrating hormone (MCH-1) receptor antagonists. The present invention also relates to pharmaceutical compositions including these compounds, and methods of preparation and use thereof.
US08697698B2 Pyrazole compounds useful as protein kinase inhibitors
This invention describes novel pyrazole compounds of formula III: wherein Z1, Z2, and Z3 are as described in the specification; Q is —S—, —O—, —N(R4)—, or —CH(R6)—; R1 is T-Ring D, wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; and R2 and R2′are as described in the specification. The compounds are useful as protein kinase inhibitors, especially as inhibitors of Aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease.
US08697691B2 Alkyl 3-((2-amidoethyl)amino)-8-azabicyclo[3.2.1]octane-8-carboxylate analogs as selective M1 agonists and methods of making and using same
In one aspect, the invention relates to compounds having a general structure: which are useful as selective allosteric or bitopic agonists of the M1 muscarinic receptor; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurodegenerative diseases, including Alzheimer's Disease. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US08697688B2 Pyrrolobenzodiazepines used to treat proliferative diseases
Pyrrolobenzodiazepine dimers I having a C2-C3 double bond and an aryl group at the C2 position on one monomer unit, and a C2-C3 double bond and either a conjugated double or triple bond at the C2 position or an alkyl group at the C2 position on the other monomer unit, and conjugates of these compounds.
US08697685B2 Chemical compounds
The invention is directed to 6-(4-pyrimidinyl)-1H-indazole derivatives. Specifically, the invention is directed to compounds according to Formula (I) wherein R1-R4 are defined herein. The compounds of the invention axe inhibitors of PDK1 and can be useful in the treatment of immune and metabolic diseases and disorders characterized by constitutively activated ACG kinases such as cancer and more specifically cancers of the breast, colon, and lung. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting PDK1 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.
US08697684B2 Azetidinyl diamides as monoacylglycerol lipase inhibitors
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein.
US08697681B2 Method for prediction of therapeutic effect of chemotherapy employing expression level of dihydropyrimidine dehydrogenase gene as measure
The present invention provides an antitumor agent comprising cisplatin and a combination drug of tegafur/gimeracil/oteracil potassium that ensures an excellent life-prolongation effect in advanced gastric cancer patients that is superior to that of the standard therapy in Europe and the U.S. using an agent that contains 5-FU and does not contain a dihydropyrimidine dehydrogenase inhibitor, by way of selecting the patients based on dihydropyrimidine dehydrogenase.
US08697680B2 Naphthoquinone derivatives useful for prevention of amyloid deposits and treatment of diseases involving amyloidogenesis
The present invention provides pharmaceutical compositions comprising substituted 1,4 naphthoquinones that are effective in preventing oligomerization of beta amyloid and subsequent pathologies associated with amyloid fibrils. These compositions are useful for the treatment of disease involving amyloidogenesis including neurodegenerative diseases such as Alzheimer's Disease or senile dementia. Particularly effective compositions comprise 1,4 naphthoquinones substituted with an amino acid residue selected from a heterocyclic or aromatic amino acid.
US08697678B2 Anaesthetic formulation
The present invention relates generally to the field of drug delivery systems for neuroactive steroid anaesthetic agents. More particularly, anaesthetic and sedative formulations are provided in the form of host/guest preparations comprising one or more neuroactive steroid anaesthetics and a cyclodextrin. Particular cyclodextrins contemplated include sulfoalkyl ether cyclodextrins and modified forms thereof.
US08697674B2 Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
The present invention relates to pharmaceutical compositions comprising xanthurenic acid derivatives, and methods of use thereof.
US08697673B2 Bicyclic pyridinones
Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined herein. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
US08697672B2 Microrna inhibition for the treatment of inflammation and myeloproliferative disorders
The present disclosure relates to the finding that microRNA-155 plays a role in inflammation, hematopoiesis and myeloproliferation, and that dysregulation of microRNA-155 expression is associated with particular myeloproliferative disorders. Disclosed herein are methods and compositions for diagnosing and treating disorders, including inflammation and myeloproliferation, modulating the levels of expression of one or more genes selected from the group consisting of Cutl1, Arnt1, Picalm, Jarid2, PU.1, Csf1r, HIF1α, Sla, Cepbβ, and Bach1, and the like.
US08697670B2 Compositions and methods of treating viral infections
The present invention relates to the field of nutraceuticals, and in particular to nutraceuticals comprising sulfated polysaccharides, Astragalus polysaccharides, resveratrol, and combinations thereof. These compositions find use in inducing physiological responses such, decreasing body fat, increasing lean body mass, alleviating the symptoms of colds, preventing the onset of colds, increasing energy, increasing the feeling of well-being in subjects, and improving skin tone and appearance.
US08697667B2 Cyclodextrin-modified polyamines for delivery of therapeutic molecules
The present invention is directed to drug delivery vehicles comprising one or more cyclodextrin moieties conjugated to a dendritic polyamine for the delivery of small molecule and protein therapeutic molecules and nucleic acid therapeutic molecules, and methods of making and using the delivery vehicles.
US08697662B2 Methods for treating Kaposi sarcoma
Methods for treating Kaposi's sarcoma involving the administration of a compound that selectively inhibits pathological production of human VEGF are described. The compound can be administered as a single-agent therapy or in combination with one or more additional therapies to a human in need of such treatment.
US08697656B2 Compounds, in particular peptides, compositions comprising them and cosmetic and dermo-pharmaceutical uses
The present invention concerns a peptide of following formula I: R being a side chain having at least one heteroatom selected from sulfur, nitrogen and oxygen in a carbonyl form (C═O); R1 being either H or a lipophilic chain; R2 being either OH or a lipophilic chain. More particularly the present invention concerns a cosmetic composition comprising a peptide as recited above and a physiologically acceptable medium. Results on the activity of the compounds are obtained and on the general state of the skin and its appendages, in particular via the stimulation of extracellular matrix components.
US08697655B2 Method of selecting polypeptide sequence, and metal oxide or silicon-containing compound binding peptide and use thereof
Provided is a peptide including the following amino acid sequence. Tyr-Xaa0-Xaa1-Tyr-Tyr-Xaa2-Xaa3-Tyr-Xaa4-Xaa5-Xaa6-Xaa7-Xaa8-Xaa9-Xaa10-Xaa11 (SEQ ID NO: 4: wherein Xaa0, Xaa1, Xaa2, Xaa3, Xaa4, Xaa5, Xaa6, Xaa7, Xaa8, Xaa9, Xaa10 and Xaa 11 represent any amino acid) or Tyr-Asn-Asp-Tyr-Tyr-Tyr-Tyr-Cys-Tyr-Arg-Asp-Tyr-Asp (SEQ ID NO: 20).
US08697652B2 Cosmetic use of at least the natural tetrapeptide Ac-Ser-Asp-Lys-Pro or one of its analogs as a skin restructuring agent
This invention relates to the cosmetic use of at least one compound of formula (I) wherein A1 is the radical corresponding to D- or L-Ser A2 is the radical corresponding to D- or L-Asp or Glu, A3 is the radical corresponding to D- or L-Lys, Arg or Orn, A4 is the radical corresponding to D- or L-pro, R1, R2 and R3 are as defined in the claims as anti-aging and restructuring agents.
US08697648B2 Protein agent for diabetes treatment and β cell imaging
The 30 amino acid peptide GLP-1 has been integrated into the stable host protein human calbindin D9k. The fusion protein binds to GLP-1R. The fusion protein agents can be useful for both diabetes treatment and GLP-1R receptor targeting MR imaging. The fusion protein comprises a first peptide that selectively binds to a site of a target cell and linked to a second peptide, where the fusion protein is more stable than the first peptide alone and may further comprise a detectable label. The first peptide of the fusion protein may be glucagon-like peptide-1 (GLP-1), glucagon-like peptide-1 (GLP-1)(7-36), or glucagon-like peptide-1 (GLP-1) (9-36), or a conservative variant thereof.
US08697640B2 Method for treating fungal infection with antifungal bifunctional molecules
The present invention is directed to a method of treating a fungal infection with a fusion peptide that includes a fungal targeting agent and a channel-forming domain consisting essentially of amino acids 451-626 of colicin Ia. The fungal targeting agent can be a pheromone, such as an alpha-mating pheromone. The fusion peptides of the peptides of the present invention are particularly useful for the treatment of fungal infections in a wide variety of organisms. The fusion peptides can be prepared from the nucleic acids, such as when a vector having the nucleic acid is included in a host cell.
US08697633B2 Dissolution of arterial plaque
Embodiments of methods of treating atherosclerosis are described. In some embodiments an emulsifier is provided to achieve levels in the systemic circulation that are effective to solubilize atherosclerotic plaque, resulting in plaque regression. In some embodiments, levels of greater than 50 μM are achieved; in some embodiments levels ranging from about 100 μM to about 600 μM are achieved; in some embodiments, levels ranging from about 100 μM to about 300 μM are achieved. Emulsifiers can include bile salts, saponins, and ionic, nonionic, and zwitterionic detergents, or salts, conjugates, hydrates, solvates, or polymorphs thereof. In some embodiments, a statin can be administered simultaneously or sequentially with an emulsifier.
US08697632B2 Amide based insulin prodrugs
Prodrug formulations of insulin and insulin analogs are provided wherein the insulin peptide has been modified by an amide bond linkage of a dipeptide prodrug element. The prodrugs disclosed herein have extended half lives of at least 10 hours, and more typically greater than 2 hours, 20 hours and less than 70 hours, and are converted to the active form at physiological conditions through a non-enzymatic reaction driven by chemical instability.
US08697630B2 Method for lowering insulin resistance
Disclosed is a method and composition for nutritionally improving glucose and insulin balance in an individual. The invention further provides a method for treating a comorbidity of diabetes. In one embodiment, the invention provides a nutritional formulation comprising: a protein source; a fat source; and a carbohydrate source, wherein the protein source, the fat source, and the carbohydrate source are in a ratio of about 1:1:1, each comprising about one third of the total calories of the composition.
US08697626B2 4,4-dimethyl-decal-1-one or -1-OL derivatives as perfuming ingredients
The present invention relates to use of a compound of formula (I) in the form of any one of its stereoisomers or a mixture thereof, and wherein the dotted lines represent a single or double bond, and at least one of said dotted lines represents a double bond; n represents simultaneously 0, in which case the oxygen atom is bounded to the cyclanic carbon atom by a double bond, or 1, in which case the oxygen atom is bounded to the cyclanic carbon atom by a single bond, each R represents a hydrogen atom or a methyl group; R1 represents a hydrogen atom or a methyl or ethyl group; and R2 represents a hydrogen atom or a methyl or ethyl group; and the groups R, R1 and R2 have in total, i.e. all together account for 1 to 4 carbon atoms; as perfuming ingredient, for instance to impart odor notes of the woody type together with balsamic/spicy and/or musky notes.
US08697624B2 Water-soluble film having blend of PVOH polymers, and packets made therefrom
Disclosed are plasticized, water-soluble films having favorable cold-water solubility, wet handling, and thermoforming characteristics, and which can include a PVOH resin made up of blend of two or more PVOH polymers each having a monomodal molecular weight distribution, and the PVOH resin characterized by a viscosity in a range of about 13.5 cP to about 20 cP (or a corresponding weight average molecular weight), a degree of hydrolysis of about 84% to about 92%, a polydispersity index value in a range of about 1 to about 5, a residual water content of about 4 wt. % to about 10 wt. %, and a Resin Selection Index value in a range of 0.255 to 0.315; methods of making the films; compositions including PVOH resins for making the films; and pouch and packet articles made from the films.
US08697623B2 Detergent composition
An automatic dishwashing detergent composition comprising by weight of the composition: a) at least 9% of coated bleach particles the particles having a coating comprising at least 5% by weight of the particle of an efflorescent material; b) at least 0.5% of granulates containing active enzyme wherein the granulates comprise efflorescent material.
US08697615B2 Polyepihalohydrin reverse emulsion breakers
A composition and method for resolving reverse emulsions and complex water external emulsions using one or more polyepihalohydrins, one or more polyelectrolytes thereof, and any combination thereof is disclosed and claimed. The disclosed invention may be used in any crude oil production process where such emulsions are encountered.
US08697612B2 Increasing fracture complexity in ultra-low permeable subterranean formation using degradable particulate
A method of increasing the fracture complexity in a treatment zone of a subterranean formation is provided. The subterranean formation is characterized by having a matrix permeability less than 1.0 microDarcy. The method includes the step of pumping one or more fracturing fluids into a far-field region of a treatment zone of the subterranean formation at a rate and pressure above the fracture pressure of the treatment zone. A first fracturing fluid of the one or more fracturing fluids includes a first solid particulate, wherein: (a) the first solid particulate includes a particle size distribution for bridging the pore throats of a proppant pack previously formed or to be formed in the treatment zone; and (b) the first solid particulate comprises a degradable material. In an embodiment, the first solid particulate is in an insufficient amount in the first fracturing fluid to increase the packed volume fraction of any region of the proppant pack to greater than 73%. Similar methods using stepwise fracturing fluids and remedial fracturing treatments are provided.
US08697609B2 Methods of using fluid loss additives comprising micro gels
Methods and fluids are provided that include, but are not limited to, a drilling fluid comprising an aqueous base fluid and a fluid loss control additive that comprises at least one polymeric micro gel and a method comprising: providing an aqueous based treatment fluid comprising a fluid loss control additive that comprises at least one polymeric micro gel; placing the aqueous based treatment fluid in a subterranean formation via a well bore penetrating the subterranean formation; allowing the fluid loss control additive to become incorporated into a filter cake located on a surface within the subterranean formation; allowing the filter cake to be degraded; and producing hydrocarbons from the formation. Additional methods are also provided.
US08697608B2 Universal fibronectin type III binding-domain libraries
Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens.
US08697606B2 Methods for discretized processing and process sequence integration of regions of a substrate
The present invention provides methods and systems for discretized, combinatorial processing of regions of a substrate such as for the discovery, implementation, optimization, and qualification of new materials, processes, and process sequence integration schemes used in integrated circuit fabrication. A substrate having an array of differentially processed regions thereon is processed by delivering materials to or modifying regions of the substrate.
US08697605B2 Polymer co-location in surface-attached biopolymers and arrays of biopolymers
Embodiments of the present invention provide substrates having controllably co-located polymers of different sequences. Methods are provided that allow the fabrication of arrays of polymers on a substrate having controllably co-located polymers in regions of the array. For example, polymers of nucleic acids and peptides having different sequences and or compositions can be co-located within a region of a substrate. Also provided are arrays of DNA polymers wherein polymers having two different sequences are co-located within a region of an array. The co-located DNA polymers can comprise complementary DNA that is able to hybridize and form double stranded DNA. Arrays having regions comprising double stranded DNA are provided.
US08697600B2 Exhaust gas purifying catalyst
An exhaust gas purifying catalyst that contains a first oxygen storage material on which no noble metal is supported and which has a pyrochlore phase type regular array structure, and a second oxygen storage material which has a higher oxygen storage rate and a lower oxygen storage capacity than the first oxygen storage material and on which a platinum group noble metal is supported.
US08697597B2 Self sustained electrochemical promotion catalysts
A method and system for the reduction of pollutant NOx gases from automobile exhaust, as well as a method of reforming hydrocarbons, using a self-sustaining catalyst comprising an ion conductive support, a dispersed cathodic phase, a dispersed anodic phase, and a dispersed sacrificial phase, and a method of forming the self-sustaining catalyst.
US08697596B2 Mixed metal oxide catalysts and catalytic conversions of lower alkane hydrocarbons
Catalytic compositions and processes are disclosed for economical conversions of lower alkane hydrocarbons. Broadly, the present invention discloses solid compositions containing mixed metal oxides that exhibit catalytic activity for ammoxidation of lower alkane hydrocarbons to produce an unsaturated nitrile in high yield. Generally, these solid oxide compositions comprise, as component elements, molybdenum (Mo), vanadium (V) niobium (Nb) and at least one active element selected from the group consisting of the elements having the ability to form positive ions. Mixed metal oxide catalytic compositions advantageously comprise one or more crystalline phases at least one of which phases has pre-determined unit cell volume and aspect ratio. Also described are methods for forming the improved catalysts having the desired crystalline structure and ammoxidation processes for conversion of lower alkanes.
US08697586B2 Fire retardant panel compositions
A fire retardant structural board is provided that includes a body of fibrous material, a triglycidyle polyester binder, a sodium borate pentahydride fire retardant, and a sodium borate pentahydride fire retardant. The body of fibrous material has a weight, first and second surfaces, first and second sides, and a thickness. The fibrous material and triglycidyle polyester are dispersed throughout the thickness of the body. The sodium borate pentahydride fire retardant is dispersed between individual fibers of the fibrous material and throughout the thickness of the body. A sodium borate pentahydride fire retardant composition also coats at least the first surface of the body.
US08697583B2 Oxidation-promoting compositions, methods of forming oxide layers, and methods of fabricating semiconductor devices
Provided according to embodiments of the present invention are an oxidation-promoting compositions, methods of forming oxide layers, and methods of fabricating semiconductor devices. In some embodiments of the invention, the oxidation-promoting composition includes an oxidation-promoting agent having a structure of A-M-L, wherein L is a functional group that is chemisorbed to a surface of silicon, silicon oxide, silicon nitride, or metal, A is a thermally decomposable oxidizing functional group, and M is a moiety that allows A and L to be covalently bonded to each other.
US08697582B2 Substrate conveying roller, thin film manufacturing device, and thin film manufacturing method
A substrate-conveying roller includes a first shell, a second shell, an internal block, a manifold, and a clearance. The first shell has a plurality of first through holes serving as supply paths for a gas. The internal block is disposed inside the first shell. The manifold is formed in the internal block so as to guide the gas to the first through holes within the region of a specific angle. The clearance is formed so as to guide the gas to the first through holes outside the region of the specific angle. The second shell has second through holes for guiding the gas from the manifold to the first through holes, and is disposed between the first shell and the internal block. The central axes of the first through hole are offset from the central axes of the second through holes.
US08697580B2 Method of forming patterns for semiconductor device
Provided is a method of forming patterns for a semiconductor device in which fine patterns and large-width patterns are formed simultaneously and adjacent to each other. In the method, a first layer is formed on a substrate so as to cover a first region and a second region which are included in the substrate. Both a blocking pattern covering a portion of the first layer in the first region and a low-density large-width pattern covering a portion of the first layer in the second region are simultaneously formed. A plurality of sacrificial mask patterns are formed on the first layer and the blocking pattern in the first region. A plurality of spacers covering exposed sidewalls of the plurality of sacrificial mask patterns are formed. The plurality of sacrificial mask patterns are removed. The first layer in the first and second regions are simultaneously etched by using the plurality of spacers and the blocking pattern as etch masks in the first region and using the low-density large-width pattern as an etch mask in the second region.
US08697572B2 Method for forming Cu film and storage medium
In a method for forming a Cu film, a CVD Cu film is formed on a CVD-Ru film that is formed on a wafer W. In the method, the wafer W having the CVD-Ru film is loaded into a chamber 1, and a film-forming source material in a vapor state is introduced into the chamber 1. The film-forming source material includes Cu(hfac)TMVS that is a Cu complex having a vapor pressure higher than that of Cu(hfac)2 produced as a by-product during the film formation. When the CVD-Cu film is formed, the pressure within the chamber 1 is controlled to a pressure at which the desorption and diffusion of Cu(hfac)2 adsorbed on the surface of the CVD Ru film proceed.
US08697570B2 Semiconductor device including contact plug and method of manufacturing the same
A semiconductor device includes a substrate having a conductive area, a first pattern formed on the substrate and having a contact hole through which the conductive area is exposed, and a contact plug in the contact hole. The contact plug includes first and second silicon layers. The first silicon layer, formed from a first compound including at least two silicon atoms, is formed in the contact hole to contact a top surface of the conductive area and a side wall of the first pattern. The second silicon layer, formed from a second compound including a number of silicon atoms less than the number of the silicon atoms of the first compound, is formed on the first silicon layer and fills a remaining space of the contact hole, the second silicon layer being spaced apart from the first pattern at an entrance of the contact hole.
US08697569B2 Non-lithographic formation of three-dimensional conductive elements
A method of forming a conductive element on a substrate and the resulting assembly are provided. The method includes forming a groove in a sacrificial layer overlying a dielectric region disposed on a substrate. The groove preferably extends along a sloped surface of the substrate. The sacrificial layer is preferably removed by a non-photolithographic method, such as ablating with a laser, mechanical milling, or sandblasting. A conductive element is formed in the groove. The grooves may be formed. The grooves and conductive elements may be formed along any surface of the substrate, including within trenches and vias formed therein, and may connect to conductive pads on the front and/or rear surface of the substrate. The conductive elements are preferably formed by plating and may or may not conform to the surface of the substrate.
US08697563B2 Method for forming semiconductor device having multiple active layer structure
A method for manufacturing a semiconductor device includes forming a transistor having a stacked structure in a peripheral circuit region to increase net die and forming a metal silicide layer over a source/drain region of a transistor formed over an upper layer to reduce a contact resistance. The semiconductor device may include: a second active region including a silicon layer connected to a first active region of a semiconductor substrate; a gate formed over the second active region; a spacer formed on sidewalls of the gate; a source/drain region form at both sides of the spacer; and a metal silicide layer formed over the gate and the source/drain region.
US08697561B2 Microelectronic structure by selective deposition
A finFET structure includes a semiconductor fin located over a substrate. A gate electrode is located traversing the semiconductor fin. The gate electrode has a spacer layer located adjoining a sidewall thereof. The spacer layer does not cover completely a sidewall of the semiconductor fin. The gate electrode and the spacer layer may be formed using a vapor deposition method that provides for selective deposition upon a sidewall of a mandrel layer but not upon an adjoining surface of the substrate, so that the spacer layer does not cover completely the sidewall of the semiconductor fin. Other microelectronic structures may be fabricated using the lateral growth methodology.
US08697558B2 Semiconductor device and manufacturing method thereof
On the top surface of a thin semiconductor wafer, top surface structures forming a semiconductor chip are formed. The top surface of the wafer is affixed to a supporting substrate with a double-sided adhesive tape. Then, from the bottom surface of the thin semiconductor wafer, a trench, which becomes a scribing line, is formed by wet anisotropic etching so that side walls of the trench are exposed. On the side walls of the trench with the crystal face exposed, an isolation layer with a conductivity type different from that of the semiconductor wafer for holding a reverse breakdown voltage is formed simultaneously with a collector region of the bottom surface diffused layer by ion implantation, followed by annealing with laser irradiation. The side walls form a substantially V-shaped or trapezoidal-shaped cross section, with an angle of the side wall relative to the supporting substrate being 30-70°. The double-sided adhesive tape is then removed from the top surface to produce semiconductor chips. With such a manufacturing method, a reverse-blocking semiconductor device having high reliability can be formed.
US08697556B2 Transistor structure having a trench drain
A semiconductor device is formed having a trench adjacent to a current carrying region of the device. The trench is formed having a depth greater than the depth of a tub region of the device. Increasing the trench depth moves a region of higher field strength from the tub region to a region along the trench. The region along the trench does not have a junction and may withstand the higher field strength.
US08697551B2 Crystalline aluminum carbide thin film, semiconductor substrate having the aluminum carbide thin film formed thereon and method of fabricating the same
Embodiments of the invention provide a crystalline aluminum carbide thin film, a semiconductor substrate having the crystalline aluminum carbide thin film formed thereon, and a method of fabricating the same. Further, the method of fabricating the AlC thin film includes supplying a carbon containing gas and an aluminum containing gas to a furnace, to growing AlC crystals on a substrate.
US08697538B1 Method of forming pattern in substrate
A method of forming a pattern in a substrate is provided, in which the substrate having a pattern region is provided first. A plurality of stripe-shaped mask layers is formed on the substrate in the pattern region. Each of at least two adjacent stripe-shaped mask layers among the stripe-shaped mask layers has a protrusion portion and the protrusion portions face to each other. A spacer is formed on sidewalls of the stripe-shaped mask layers, wherein a thickness of the spacer is greater than a half of a distance between two of the protrusion portions. Subsequently, the stripe-shaped mask layers are removed. An etching process is performed by using the spacer as a mask to form trenches in the substrate. Thereafter, the trenches are filled with a material.
US08697535B2 Thin film transistor substrate and method for fabricating the same
A thin film transistor substrate includes a substrate, a gate electrode on the substrate, an active layer on or below the gate electrode (the active layer at least partially overlapping the gate electrode) including a first active region and a second active region, the first active region and the second active region facing each other and extending beyond the gate electrode, a source electrode electrically connected to the first active region and a drain electrode electrically connected to the second active region, wherein the active layer includes a recess region which is at least partially recessed from a surface of the active layer facing the gate electrode, and the recess region includes a portion extending between the first active region and the second active region.
US08697533B2 Method for obtaining smooth, continuous silver film
A method for forming a semiconductor device including a resistive memory cell includes providing a substrate having an upper surface. A first conductive layer is formed over the upper surface of the substrate. An amorphous silicon layer is formed over the first conductive layer. A surface of the amorphous silicon layer is cleaned to remove native oxide formed on the surface of the amorphous silicon layer. A silver layer is deposited over the amorphous silicon layer after removing the native oxide by performing the cleaning step. The resistive memory cell includes the first conductive layer, the amorphous silicon layer, and the second conductive layer. The surface of the amorphous silicon layer is cleaned to prevent silver agglomeration on the native oxide.
US08697532B2 InP based heterojunction bipolar transistors with emitter-up and emitter-down profiles on a common wafer
A wafer comprising at least one emitter-up Heterojunction Bipolar Transistor (HBT) and at least one emitter-down HBT on a common InP based semiconductor wafer. Isolation and N-type implants into the device layers differentiate an emitter-down HBT from an emitter-up HBT. The method for preparing a device comprises forming identical layers for all HBTs and performing ion implantation to differentiate an emitter-down HBT from an emitter-up HBT.
US08697531B2 Method for fabricating a semiconductor device having stress/strain and protrusion
A semiconductor device includes a silicon substrate having a protrusion, a gate insulating film formed over an upper surface of the protrusion of the silicon substrate, a gate electrode formed over the gate insulating film, a source/drain region formed in the silicon substrate on the side of the gate electrode, a first side wall formed over the side surface of the protrusion of the silicon substrate, the first side wall containing an insulating material, a second side wall formed over the first side wall, the second side wall having a bottom portion formed below the upper surface of the protrusion of the silicon substrate, the second side wall containing a material having a Young's modulus greater than that of the silicon substrate, and a stress film formed over the gate electrode and the second side wall.
US08697522B2 Bulk finFET with uniform height and bottom isolation
A fin Field Effect Transistor (finFET), an array of finFETs, and methods of production thereof. The finFETs are provided on an insulating region, which may optionally contain dopants. Further, the finFETs are optionally capped with a pad. The finFETs provided in an array are of uniform height.
US08697520B2 Method of forming an asymmetric poly gate for optimum termination design in trench power MOSFETS
A semiconductor device having a plurality of transistors includes a termination area that features a transistor with an asymmetric gate.
US08697517B2 Reduced substrate coupling for inductors in semiconductor devices
The present disclosure provides reduced substrate coupling for inductors in semiconductor devices. A method of fabricating a semiconductor device having reduced substrate coupling includes providing a substrate having a first region and a second region. The method also includes forming a first gate structure over the first region and a second gate structure over the second region, wherein the first and second gate structures each include a dummy gate. The method next includes forming an inter layer dielectric (ILD) over the substrate and forming a photoresist (PR) layer over the second gate structure. Then, the method includes removing the dummy gate from the first gate structure, thereby forming a trench and forming a metal gate in the trench so that a transistor may be formed in the first region, which includes a metal gate, and an inductor component may be formed over the second region, which does not include a metal gate.
US08697514B2 FinFET device
A method for forming a field effect transistor device includes patterning an arrangement of fin portions on a substrate, patterning a gate stack portion over portions of the fin portions and the substrate, growing an epitaxial material from the fin portions that electrically connects portions of adjacent fin structures, and removing a portion of the gate stack portion to expose a portion of the substrate.
US08697512B2 Systems and methods for integrated circuits comprising multiple body biasing domains
Systems and methods for integrated circuits comprising multiple body biasing domains. In accordance with a first embodiment, a semiconductor structure comprises a substrate of first type material. A first closed structure comprising walls of second type material extends from a surface of the substrate to a first depth. A planar deep well of said second type material underlying and coupled to the closed structure extends from the first depth to a second depth. The closed structure and the planar deep well of said second type material form an electrically isolated region of the first type material. A second-type semiconductor device is disposed to receive a first body biasing voltage from the electrically isolated region of the first type material. A well of the second-type material within the electrically isolated region of the first type material is formed and a first-type semiconductor device is disposed to receive a second body biasing voltage from the well of second-type material.
US08697508B2 Semiconductor process
A semiconductor process includes the following steps. A gate structure is formed on a substrate. An oxide layer is formed and covers the gate structure and the substrate. A plasma process without oxygen is performed to densify the oxide layer. A material layer is formed and covers the oxide layer. The material layer and the oxide layer are etched to form a dual spacer.
US08697504B2 Organic thin film transistors, active matrix organic optical devices and methods of making the same
A method of manufacturing an organic thin film transistor, comprising: providing a substrate comprising source and drain electrodes defining a channel region; subjecting at least the channel region to a cleaning treatment step; and depositing organic semiconductive material from solution into the channel region by inkjet printing.
US08697498B2 Methods of manufacturing three dimensional semiconductor memory devices using sub-plates
A method of manufacturing a Three Dimensional (3D) semiconductor memory device can be provided by forming at least one trench in a plate stack structure to divide the plate stack structure into a plurality of sub-plate stack structures between forming a plurality of vertical active patterns in the plate stack structure and forming pads of a stepped structure from the plate stack structure.
US08697494B2 Method of manufacturing a flip chip package and apparatus to attach a semiconductor chip used in the method
A method and apparatus to manufacture a flip chip package includes dotting a flux on a first preliminary bump of a package substrate, attaching a preliminary bump of a first semiconductor chip to the first preliminary bump of the package substrate via the flux, dotting a flux on a second preliminary bump of the package substrate, and attaching a preliminary bump of a second semiconductor chip to the second preliminary bump of the package substrate via the flux. Accordingly, an evaporation of the flux on the preliminary bump of the package substrate may be suppressed.
US08697493B2 Bonding surfaces for direct bonding of semiconductor structures
Methods of directly bonding a first semiconductor structure to a second semiconductor structure include directly bonding at least one device structure of a first semiconductor structure to at least one device structure of a second semiconductor structure in a conductive material-to-conductive material direct bonding process. In some embodiments, at least one device structure of the first semiconductor structure may be caused to project a distance beyond an adjacent dielectric material on the first semiconductor structure prior to the bonding process. In some embodiments, one or more of the device structures may include a plurality of integral protrusions that extend from a base structure. Bonded semiconductor structures are fabricated using such methods.
US08697492B2 No flow underfill
A method for making a microelectronic assembly includes providing a microelectronic element with first conductive elements and a dielectric element with second conductive elements. At least some of either the first conductive elements or the second conductive elements may be conductive posts and other of the first or second conductive elements may include a bond metal disposed between some of the conductive posts. An underfill layer may overly some of the first or second conductive elements. At least one of the first conductive elements may be moved towards the other of the second conductive elements so that the posts pierce the underfill layer and at least deform the bond metal. The microelectronic element and the dielectric element can be heated to join them together. The height of the posts above the surface may be at least forty percent of a distance between surfaces of the microelectronic element and dielectric element.
US08697491B2 Semiconductor package and method of fabricating the same
A semiconductor package is provided. The semiconductor package includes a package body, a plurality of semiconductor chips, and an external connection terminal. The package body is stacked with a plurality of sheets where conductive patterns and vias are disposed. The plurality of semiconductor chips are inserted into insert slots extending from one surface of the package body. The external connection terminal is provided on other surface opposite to the one surface of the package body. Here, the plurality of semiconductor chips are electrically connected to the external connection terminal.
US08697490B2 Flip chip interconnection structure
A flip chip interconnection structure is formed by mechanically interlocking joining surfaces of a first and second element. The first element, which may be a bump on an integrated circuit chip, includes a soft, deformable material with a low yield strength and high elongation to failure. The surface of the second element, which may for example be a substrate pad, is provided with asperities into which the first element deforms plastically under pressure to form the mechanical interlock.
US08697489B2 Package structure and package process
A package structure and a package process are provided. In the package process, firstly, a first electronic component having a plurality of first conductive bumps at a bottom thereof is provided. Then, a first insulation paste is coated on the first conductive bumps. The first electronic component is disposed on a circuit substrate having a plurality of substrate pads, and the first conductive bumps are respectively situated on the substrate pads. Next, a heating process is performed to both of the first conductive bumps and the first insulation paste, wherein the first conductive bumps is reflowed to bond the first electronic component and the substrate pads, and the first insulation paste is cured.
US08697487B2 Memory device manufacturing method with memory element having a metal-oxygen compound
Memory devices based on tungsten-oxide memory regions are described, along with methods for manufacturing and methods for programming such devices. The tungsten-oxide memory region can be formed by oxidation of tungsten material using a non-critical mask, or even no mask at all in some embodiments. A memory device described herein includes a bottom electrode and a memory element on the bottom electrode. The memory element comprises at least one tungsten-oxygen compound and is programmable to at least two resistance states. A top electrode comprising a barrier material is on the memory element, the barrier material preventing movement of metal-ions from the top electrode into the memory element.
US08697485B2 Printed electronics
Printed electronic device comprising a substrate onto at least one surface of which has been applied a layer of an electrically conductive ink comprising functionalized graphene sheets and at least one binder. A method of preparing printed electronic devices is further disclosed.
US08697484B2 Method and system for setting a pinned layer in a magnetic tunneling junction
A method and system for setting the direction of pinned layers in a magnetic junction are described. In one aspect, a magnetic field greater than the coercivity of the layers in a pinned layer but less than the coupling field between the layers is applied. In another aspect the pinned layers are switched from an anti-dual state to a dual state using a spin transfer torque current. In another aspect, a magnetic junction having a partial perpendicular anisotropy (PPMA) layer in the pinned layer is provided. In some aspects, the PPMA layer is part of a synthetic antiferromagnetic structure. In some embodiments, a decoupling layer is provided between the PPMA layer and another ferromagnetic layer in the pinned layer.
US08697480B1 Method for treating a semiconductor
Methods for treating a semiconductor material, and for making devices containing a semiconducting material, are presented. One embodiment is a method for treating a semiconductor material that includes a chalcogenide. The method comprises contacting at least a portion of the semiconductor material with a chemical agent. The chemical agent comprises a solvent, and an iodophor dissolved in the solvent.
US08697479B2 Method for producing nanoparticles
Some embodiments disclosed herein are related to methods of preparing a nanoparticle composition comprising: providing an aerosol comprising a plurality of droplets of a precursor solution comprising at least one nanoparticle precursor and an expansive component; passing the aerosol through a plasma; and collecting a nanoparticle composition product from the carrier gas which has exited the plasma. Some embodiments relate to nanoparticle compositions provided by this process. Some embodiments relate to light-emitting diodes or light emitting devices comprising these compositions.
US08697477B2 Method for production of solid-state imaging element, solid-state imaging element, and imaging apparatus
Disclosed herein is a method for producing a solid-state imaging element which has pixels, each including a sensor section that performs photoelectric conversion and a charge transfer section that transfers charges generated by the sensor section. The method includes: forming an impurity region of the first conduction type and a second impurity region of the second conduction type on the impurity region of the first conduction type by ion implantation by using the same mask; forming on the surface of the semiconductor substrate a transfer gate constituting the charge transfer section which extends over the second impurity region of the second conduction type; forming a charge accumulating region of the first conduction type constituting the sensor section by ion implantation; and forming a first impurity region of the second conduction type, which has a higher impurity concentration than the second impurity region of the second conduction type, by ion implantation.
US08697470B2 Miniature MEMS condenser microphone packages and fabrication method thereof
MEMS microphone packages and fabrication methods thereof are disclosed. One method for fabricating a MEMS microphone package, includes providing a substrate, forming a cavity enclosed by a top cover part, wherein a housing wall part surrounds and supports the top cover part, and the substrate supports the housing wall part and the cover part, forming a MEMS sensing element and an IC chip inside the cavity, forming an opening comprising an acoustic passage connecting the cavity to an ambient space, and forming a conductive casing enclosing the top cover part and the housing wall, wherein the conductive casing is soldered to a PCB board and is electrically connected to a common analog ground lead on the PCB board.
US08697467B2 Surface and gas phase doping of III-V semiconductors
Compound semiconductor devices and methods of doping compound semiconductors are provided. Embodiments of the invention provide post-deposition (or post-growth) doping of compound semiconductors, enabling nanoscale compound semiconductor devices including diodes and transistors. In one method, a self-limiting monolayer technique with an annealing step is used to form shallow junctions. By forming a sulfur monolayer on a surface of an InAs substrate and performing a thermal annealing to drive the sulfur into the InAs substrate, n-type doping for InAs-based devices can be achieved. The monolayer can be formed by surface chemistry reactions or a gas phase deposition of the dopant. In another method, a gas-phase technique with surface diffusion is used to form doped regions. By performing gas-phase surface diffusion of Zn into InAs, p-type doping for InAs-based devices can be achieved. Both bulk and nanowire devices using compound semiconductors can be fabricated using these surface and gas-phase doping processes.
US08697466B2 Method of manufacturing nitride semiconductor device
A method of manufacturing a nitride semiconductor device includes the step of forming a second nitride semiconductor layer having an inclined facet by metal-organic chemical vapor deposition, in which a molar flow ratio of a group V element gas to a group III element gas that are supplied to a growth chamber of a metal-organic chemical vapor deposition growth apparatus is set at 240 or less.
US08697465B2 LED epitaxial structure and manufacturing method
An LED epitaxial structure includes a substrate, a buffer layer and an epitaxial layer. The buffer layer is grown on a top surface of the substrate, and the epitaxial layer is formed on a surface of the buffer layer. The epitaxial layer has a first n-type epitaxial layer and a second n-type epitaxial layer. The first n-type epitaxial layer is formed between the buffer layer and the second n-type epitaxial layer. The first n-type epitaxial layer has a plurality of irregular holes therein.
US08697463B2 Manufacturing method of a light-emitting device
A method for manufacturing a light-emitting device includes steps of: providing a light-emitting wafer including an upper surface and a lower surface opposite to the upper surface; setting a plurality of scribing streets on the upper surface of the light-emitting wafer; irradiating a laser beam to form a plurality of cutting regions along the scribing streets, wherein each of the plurality of cutting regions has a sharp end, or the plurality of cutting regions forms a specific pattern in a cross-sectional view; and forming a plurality of light-emitting devices by connecting the plurality of cutting regions and extending the plurality of cutting regions from the respective sharp ends thereof to the lower surface of the light-emitting wafer.
US08697461B2 LED module and manufacturing method thereof
There is provided a manufacturing method of an LED module including: forming an insulating film on a substrate; forming a first ground pad and a second ground pad separated from each other on the insulating film; forming a first division film that fills a space between the first and second ground pads, a second division film deposited on a surface of the first ground pad, and a third division film deposited on a surface of the second ground pad; forming a first partition layer of a predetermined height on each of the division films; sputtering seed metal to the substrate on which the first partition layer is formed; forming a second partition layer of a predetermined height on the first partition layer; forming a first mirror connected with the first ground pad and a second mirror connected with the second ground pad by performing a metal plating process to the substrate on which the second partition layer is formed; removing the first and second partition layers; connecting a zener diode to the first mirror and connecting an LED to the second mirror; and depositing a fluorescent material so as to fill a space formed by the first mirror and the second mirror.
US08697460B2 Methods for pattering an epitaxial substrate and forming a light-emitting diode with nano-patterns
A method for patterning an epitaxial substrate with nano-patterns, includes: forming a plurality of zinc oxide nano-particles on an epitaxial substrate; dry-etching the epitaxial substrate exposed from the zinc oxide nano-particles to form nano-patterns corresponding to the zinc oxide nano-particles; and removing the zinc oxide nano-particles on the epitaxial substrate. A method for forming a light-emitting diode having a patterned epitaxial substrate with the nano-patterns is also disclosed.
US08697458B2 Silicone coated light-emitting diode
A silicone protective coating for an electronic light source and a method for applying the coating over an exposed or outer surface of the electronic light source assembled as part of or mounted to a circuit board or other substrate.
US08697456B2 Methods of adding pads and one or more interconnect layers to the passivated topside of a wafer including connections to at least a portion of the integrated circuit pads thereon
A pattern of conductive ink is disposed on the topside of the unsingulated integrated circuits of a wafer, and, typically after wafer probing, the pattern of conductive ink is removed. The conductive ink pattern provides an electrical pathway between bond pads on an integrated circuit and large contact pads disposed on the topside of the integrated circuit. Each of the large contact pads is much greater in area than the corresponding bond pads, and are spaced apart so that the pitch of the large contact pads is much greater than that of the bond pads. In one aspect of the present invention, the conductive ink includes a mixture of conductive particles and wafer bonding thermoset plastic. In another aspect of the present invention, the conductive ink is heated and disposed on a wafer by an ink jet printing system.
US08697449B2 Optical blood coagulation monitor and method
An optical blood coagulation monitor and method. The monitor has a blood sample holder, a laser with its output light directed through the blood sample, a two-dimensional detector that is able to detect light at the laser light wavelength and that has a detector output, optics for imaging onto the detector laser light that is forward scattered by the blood, and a data analysis system, responsive to the detector output, that is adapted to analyze the detected light to provide information on time-resolved coagulation and clotting properties of the blood.
US08697447B2 Cleavable surfactants and methods of use thereof
The present invention includes a cleavable surfactant/detergent compound of the following formula: wherein the variables are defined herein. Embodiments of the cleavable surfactant/detergent compound are useful, for example, in methods for isolating a hydrophobic molecule that include providing a plasma comprising a hydrophobic molecule, applying the cleavable surfactant to the plasma so that the surfactant engages the hydrophobic molecule, cleaving the surfactant from the hydrophobic molecule, and analyzing said hydrophobic molecule.
US08697439B2 Direct protein delivery with engineered microvesicles
The present invention relates to direct protein delivery with engineered micro vesicles.
US08697438B2 Cell cultivation method and cell culture
Provided is a cell cultivation method in which the cell is cultured using a peptide hydrogel as a scaffold, for carrying out high-dimensional culture of a cell such as porcine hepatocyte, human hepatocyte, porcine pancreatic islet or human pancreatic islet for a long period under conditions where cell survival, cell morphology and cell functions are maintained. Also provided are a cell culture including a cell and a peptide hydrogel obtained by the above-described cultivation method, a bioreactor including the cell culture, and a cell preparation including the cell culture.
US08697437B1 Magnetic metabolite and diagnostic transfer disks
A magnetic, selectively permeable metabolite transfer disk for the cell-free transfer of metabolites and other molecules produced by microbial colonies is described. The metabolite transfer disk is comprised of at least three layers including: (1) an adhesion layer; (2) a gel layer comprising agar or other cushioning gel matrix; and (3) a bottom surface comprising one or more fluid-permeable filters of variable pore size to enable the diffusion of small molecules into the gel while blocking passage of cells. A diagnostic transfer disk is also described that can be used for biochemical and microbial characterization. The diagnostic transfer disk is similar to the metabolite transfer disk with the added benefit of the top layer being transparent and indicator reagents being added to the disk for microbial characterization. The diagnostic transfer disk can be altered into a wound dressing that provides for the diagnosis of human disease, namely infection, while concurrently aiding in treatment and protection of such acute injuries as lacerations or burns.
US08697435B2 Integrated sample preparation and analyte detection
A system for sample preparation and analyte detection includes a cartridge, with a fluidic channel, a waveguide, and a capture spot. The system further includes a force field generator, an imaging system, and a fluid, which includes a sample potentially containing a target analyte, first type particles, which include binding moieties specific for the target analyte and are responsive to a force field, and second type particles, which include binding moieties specific for the target analyte and are capable of generating a signal. When the sample contains the target analyte, specific binding interactions between the target analyte and binding moieties link first and second type particles via the target analyte to form multiple-particle complex capturable at a capture spot. The force field allows manipulation of the particles and multiple-particle complex such that the detected signal from the second type particles is indicative of the target analyte within the sample.
US08697434B2 Detection of phage amplification by SERS nanoparticles
A phage specific antibody presenting particle, devices and methods related to detection of phage amplification are provided.
US08697429B2 Method for dyeing a textile product using Neem and Holy basil extract
A process of preparing garments and natural textile products using natural fiber, yarns and fabric is provided. The process involves treating the natural textile products with natural dyes converted into micro-sized and nano-sized particles. The textile product is also treated with bio-enzymes and natural ingredients at all stages. A process of preparing garments using Neem (Azadirachta Indica) and Holy Basil (Ocimum Sanctum or Tulsi) is also provided.
US08697427B2 Recombinant microalgae cells producing novel oils
Disclosed herein are obligate heterotrophic microalgae cells containing an exogenous gene. In some embodiments the gene is a sucrose utilization gene, and further disclosed are methods of manufacturing triglyceride oils using sugar cane or sugar beets as a feedstock in a heterotrophic fermentation. In other embodiments the feedstock is depolymerized cellulosic material. Also disclosed are cells that produce medium chain fatty acids at levels not produced in non-recombinant cells of the same species and genus.
US08697426B2 Contaminant control in Zymomonas fermentation using virginiamycin
Contamination was controlled in fermentations using Zymomonas mobilis as the biocatalyst, without negative impact on fermentation production, by the addition of virginiamycin. The effective concentration of virginiamycin was found to be dependent upon the type of fermentation medium used.
US08697424B2 Method for manufacturing red mold dioscorea
The present invention discloses a method for manufacturing red mold dioscorea, and the method comprises the following steps: washing and cutting a fresh dioscorea into pieces with a specific dimension; drying the pieces of the fresh dioscorea for making the dried dioscorea contain a specific water content and a specific sulfur content; adding some water with an appropriate ratio to fresh dioscorea or dried dioscorea; sterilizing the dioscorea; after the dioscorea being cooled down, inoculating the dioscorea with Monascus species; cultivating the dioscorea with an appropriate temperature, an appropriate humidity and an appropriate shacking frequency for an appropriate time period; and drying the cultivated red mold dioscorea with an appropriate water content.
US08697420B2 Method for producing corn gluten hydrolysate and corn gluten hydrolysate using the same
Provided is a method for producing corn gluten hydrolysate comprising: (a) separating corn gluten protein by removing carbohydrate, water soluble sugars, inorganic materials and fiber material; (b) preparing corn gluten protein lysate by carrying out acid hydrolysis, enzymatic hydrolysis or natural fermentation; and (c) increasing a content of branch chain amino acid (BCAA) which is included in the hydrolysate by isolating, concentrating, precipitating, desalting and filtering the resultant corn gluten protein lysate. With improved pre-treatment and concentration processes as compared with the conventional method, the hydrolysate prepared according to the present invention is rich in amino acids and low-molecular-weight peptides. In particular, free amino acids and branched-chain amino acids (BCAA) are included in large quantity.
US08697419B2 Compositions and methods for culturing spirochetes
The present invention relates to methods for culturing spirochetes, in particular Borrelia burgdorferi. The present invention also provides methods of identifying spirochetes present in a biological sample. The present invention further provides methods of diagnosing diseases cause by a spirochete infection, such as Lyme disease, syphilis, and multiple sclerosis. The present invention further provides methods for identifying spirochete susceptibilities to antimicrobials and antimicrobial compositions and cocktails. The present invention also provides methods for treating subjects suspected of having a spirochete infection.
US08697414B2 Degradable clostridial toxins
The specification discloses Clostridial toxins or Clostridial toxin chimeras comprising an inactivation cleavage site, polynucleotide molecules encoding such toxins or chimeras, compositions comprising such toxins or chimeras, and method of producing such toxins or chimeras.
US08697410B2 SSO7-polymerase conjugates with decreased non-specific activity
Improved Sso7-polymerase conjugate proteins are provided.
US08697409B2 Ketoreductase mutant
Disclosed are a ketoreductase mutant which can be used for an efficient production of daunorubicin derivatives, a DNA encoding the mutant, a transformant prepared by introducing the DNA thereinto to produce a daunorubicin derivative, and a process of producing a daunorubicin derivative using the transformant. The ketoreductase mutant has an amino acid sequence in which one amino acid residue or two or more amino acid residues selected from the group consisting of amino acids located at positions corresponding to the 42nd, 149th, 153rd, 270th, and 306th amino acids in the amino acid sequence of a ketoreductase (EvaE) from a chlororemomycin-producing bacterium (Amycolatopsis orientalis) are substituted with another amino acid residues.
US08697408B2 Ligation enhancement
Compositions and methods are provided for enhancing enzymatic ligation between nucleic acid fragments that relies on one or more small molecule enhancers having a size of less than 1000 daltons. For example, enhancement of ligation efficiencies are observed for double-stranded nucleic acid fragments that are blunt-ended, have a single nucleotide overhang at the ligation end, or have staggered ends compared to ligation under similar conditions in the absence of the one or more small molecule ligation enhancer. The use of small molecule enhancers for ligating nucleic acids results in an increased number of transformed host cells after transformation with the ligated molecules. This enhancement can be observed with chemically transformed host cells and with host cells transformed by electroporation.
US08697407B2 Compositions and methods for inhibiting MMSET
The present invention relates to agents that find use in the treatment, management, and/or study of cancer. In particular, the present invention relates to agents (e.g., small molecules, nucleic acids) that affect MMSET expression or activity.
US08697406B2 Direct catalytic conversion of sugars to ethanol
Sugars comprising the monosaccharides glucose and fructose, and the disaccharides sucrose and mannose are catalytically converted to ethanol in a sulfate fortified acid medium in the presence of transition metal compounds possessing a degree of symmetry. This is not a fermentation process but is a catalytic chemical process where conversion efficiency is improved by saturating the acidic reaction mixture with inorganic sulfate salts to reduce competitive reactions. Ethanol formed during the reaction is removed by distillation facilitating a continuous process.
US08697402B2 Glycerol feedstock utilization for oil-based fuel manufacturing
The invention provides methods of manufacturing biodiesel and other oil-based compounds using glycerol and combinations of glycerol and other feedstocks as an energy source in fermentation of oil-bearing microorganisms. Methods disclosed herein include processes for manufacturing high nutrition edible oils from non-food feedstock materials such as waste products from industrial waste transesterification processes. Also included are methods of increasing oil yields by temporally separating glycerol and other feedstocks during cultivation processes. Also provided herein are oil-bearing microbes containing exogenous oil production genes and methods of cultivating such microbes on glycerol and other feedstocks.
US08697401B2 Method for synthesizing an ω-amino acid or ester from a monounsaturated fatty acid or ester
The invention relates to a method for synthesizing ω-aminoalkanoic acids or esters thereof from unsaturated natural fatty acids, passing through a monounsaturated dinitrile intermediate compound. The method of the invention is simple to carry out and, compared to other known methods, avoids the environmental constraints and economic disadvantages due to reaction by-products.
US08697399B2 Nucleic acid size detection method
The present invention provides methods of determining the size of a particular nucleic acid segment of interest in a sample of nucleic acids through fragmentation of DNA, size fractionation, an optional second fragmentation, and identification using a marker sequence. In particular aspects, an expansion or reduction of tandem repeat sequences can be detected. In further aspects, carriers and individuals afflicted with fragile X syndrome or other diseases associated with tandem repeats can be distinguished from normal individuals.
US08697398B2 Compositions and methods for bacterial production of chondroitin
The invention relates to the field of recombinant DNA technology for the production of chondroitin, including the production of chondroitin sulfate via a combination of recombinant bacterial fermentation and post-fermentation sulfation.
US08697394B2 Production of modified glycoproteins having multiple antennary structures
The present invention relates to eukaryotic host cells, especially lower eukaryotic host cells, having modified oligosaccharides which may be modified further by heterologous expression of a set of glycosyltransferases, sugar and sugar nucleotide transporters to become host-strains for the production of mammalian, e.g., human therapeutic glycoproteins. The process provides an engineered host cell which can be used to express and target any desirable gene(s) involved in glycosylation. Host cells with modified lipid-linked oligosaccharides are created or selected. N-glycans made in the engineered host cells exhibit GnTIII, GnTIV, GnTV, GnT VI or GnTIX activity, which produce bisected and/or multiantennary N-glycan structures and may be modified further by heterologous expression of one or more enzymes, e.g., glycosyltransferases, sugar, sugar nucleotide transporters, to yield human-like glycoproteins. For the production of therapeutic proteins, this method may be adapted to engineer cell lines in which any desired glycosylation structure may be obtained.
US08697391B2 Method of determining cell number or viability using hydroxyethyldisulfide
A method for determining the percentage of live cells or viability of cells in a sample is disclosed. In this method, a cell-containing sample is contacted with hydroxyethyldisulfide and the amount of mercaptoethanol produced is measured. The amount of mercaptoethanol is then compared to reference standard curves to determine the percentage of live cells in the sample or the viability of the cells.
US08697390B2 Method and kit for examination of cells using N-(9-acridinyl) maleimide (NAM) or using 7-diethylamino-3-((4′-iodacetyl)amino)phenyl)-4-methylkcoumarin (CPI)
The present invention provides simple, rapid methods and procedures for analyzing cells, hereunder quantitative and qualitative assessment of cells. The present invention relates to the use of N-(9-acridinyl)maleimide (NAM) or to the use of 7-diethylamino-3-((4′-(iodoacetyl)amino)phenyl)-4-methylcoumarin (CPI), particularly detectable upon its reaction with species (e.g., sulphur-containing species) present in higher concentrations in intact (e.g., living) cells than in non-intact (e.g., dead) cells. The present invention also relates to the use of NAM or to the use of 7-diethylamino-3-((4′-(iodoacetyl)amino)phenyl)-4-methylcoumarin (CPI), particularly detectable upon its reaction with species present in intact and/or non-intact cells. Moreover, the present invention relates to the use of measuring techniques and/or instruments coupled with the use of NAM or with the use of 7-diethylamino-3-((4′-(iodoacetyl)amino)phenyl)-4-methylcoumarin (CPI). The invention further relates to compositions used in methods for analyzing cells.
US08697389B2 Cell labeling and imaging using multifunctional perfluorocarbon nanoemulsion
The present invention relates to cell labeling and imaging using a multifunctional perfluorocarbon (PFC) nanoemulsion. In particular, the perfluorocarbon nanoemulsion containing optical nanoparticle is provided with both optical characteristics and 19F magnetic resonance characteristics, thus can be used for magnetic resonance imaging (MRI) and optical imaging (OI) simultaneously. Cell labeling and imaging using the perfluorocarbon nanoemulsion containing quantum dot nanoparticle exerted no effect on cell viability. Therefore, perfluorocarbon nanoemulsion can be applied to methods for multifunctional and effectively cell labeling and imaging.
US08697388B2 Heavy metal biosensor
Compositions and methods are provided for detection of certain heavy metals using bacterial whole cell biosensors.
US08697374B2 Antibodies to Clostridium difficile spores and uses thereof
The present invention provides antibodies that bind to the endospore of the bacterium Clostridium difficile, methods of making such antibodies, and methods of using such antibodies, including methods of detecting C. difficile endospores.
US08697367B2 Markers for detection of complications resulting from in utero encounters
Described herein are biomarkers, such as protein biomarkers, which are diagnostic of and predictive for complications that result from an in utero encounter, such as an infection by the fetus, that can lead to premature birth (PTB). The biomarkers can be used to identify fetuses and newborns at risk for complications of PTB, such as (Early Onset Neonatal Sepsis) EONS, intra-ventricular hemorrhage (IVH) and other poor outcomes.
US08697366B2 Anti-cancer drug screening method using RORα
The present invention relates to a method for screening an anticancer agent using RORα, the method comprising the steps of: culturing cells; bringing a potential substance into contact with the cells; determining whether the phosphorylation level of RORα in the cells increases as compared to that in control cells (not brought into contact with the potential substance); and selecting the potential substance as an anticancer agent if the phosphorylation level of RORα in the cells increases.
US08697363B2 Methods for detecting multiple target nucleic acids in multiple samples by use nucleotide tags
The present invention provides assay methods that increase the number of samples and/or target nucleic acids that can be analyzed in a single assay. In certain embodiments, an assay method entails separately subjecting S samples to an encoding reaction that produces a set of T tagged target nucleotide sequences, each tagged target nucleotide sequence including a sample-specific nucleotide tag and a target nucleotide sequence. In some embodiments, an assay method entails separately subjecting S samples to an encoding reaction that produces a set of T tagged target nucleotide sequences, each tagged target nucleotide sequence including a first nucleotide tag linked to a target nucleotide sequence, which is linked to a second nucleotide tag. In either case, the tagged target nucleotide sequences from the S samples can be mixed to form an assay mixture and subsequently assayed.
US08697359B1 CRISPR-Cas systems and methods for altering expression of gene products
The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for utilizing the CRISPR-Cas system.
US08697358B2 Non-invasive method for diagnosis of prostate cancer
The present invention relates on a non-invasive method for diagnosing prostate cancer and/or assessing the risk of a subject acquiring prostate cancer comprising the analysis of the expression of the marker gene hepsin in an urine sample. It further relates on a non-invasive method for diagnosing prostate cancer and/or assessing the risk of a subject acquiring prostate cancer by determining the expression levels of the marker genes hepsin, EZH2, prostein and PCA3.
US08697357B2 Method for detection of methylcytosine using photoresponsive probe
The present invention provides a method for detecting methylcytosine in DNA rapidly, conveniently, and with high sensitivity. The present invention relates to a method for detecting methylcytosine by using a methylcytosine photocoupling agent (a photoresponsive probe) consisting of nucleic acids having a group represented by the Formula (I), (II), (III) or (IV) as a base moiety.
US08697355B2 Methods and compositions for determining the purity of chemically synthesized nucleic acids
This application describes an antibody that specifically binds to a synthetic oligomer (e.g., an oligonucleotide or oligopeptide) having a organic protecting group covalently bound thereto, which antibody does not bind to that synthetic oligomer when the organic protecting group is not covalently bound thereto. Methods of making and using such antibodies are also disclosed, along with cells for making such antibodies and articles carrying immobilized oligomers that can be used in assay procedures with such antibodies.
US08697354B2 RNA-exit-channel: target and method for inhibition of bacterial RNA polymerase
The invention provides a target and methods for specific binding and inhibition of RNAP from bacterial species. The invention is directed to a method for identifying agents that bind to a bacterial RNAP homologous RNA-exit-channel amino-acid sequence, comprising preparing a reaction solution comprising the agent to be tested and an entity comprising a bacterial RNAP homologous RNA-exit-channel amino-acid sequence, and detecting presence or amount of binding. The invention has applications in control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, and antibacterial therapy.
US08697353B2 Immunization compositions and methods
The present invention provides methods and compositions to induce neutralizing antibodies in mammals to serotypes of dengue virus, measles virus, mumps virus, rubella and/or VZV virus.
US08697352B2 Nucleic acid sequences that can be used as primers and probes in the amplification and detection of all subtypes of HIV-1
The present invention is related to nucleic acid sequences that can be used in the field of virus diagnostics, more specifically the diagnosis of infections with the AIDS causing Human Immuno-deficiency Virus (HIV). With the present invention nucleotide sequences are provided that can be used as primers and probes in the amplification and detection of HIV-1 nucleic acid. The oligonucleotide sequences provided with the present invention are located in the LTR part of the HIV viral genome. It has been found that, by using the sequences of the present invention in methods for the amplification and detection of nucleic acid a sensitive and specific detection of HIV-1 can be obtained. The benefit of the sequences of the present invention primarily resides in the fact that, with the aid of primers and probes comprising the sequences according to the invention the nucleic acid of all presently known subtypes of HIV-1 can be detected with high accuracy and sensitivity. So far no primer pairs or hybridization probes have been developed that would allow the detection of such a broad range of HIV-1 variants. The oligonucleotide sequences according to the present invention are especially useful in methods for the amplification of nucleic acid.
US08697345B2 Photoresist stripping solution and a method of stripping photoresists using the same
A photoresist stripping solution comprising (a) a specified quaternary ammonium hydroxide, such as tetrabutylammonium hydroxide, tetrapropylammonium hydroxide, methyltributylammonium hydroxide or methyltripropylammonium hydroxide, (b) a water-soluble amine, (c) water, (d) a corrosion inhibitor and (e) a water-soluble organic solvent, the compounding ratio of component (a) to component (b) being in the range of from 1:3 to 1:10 by mass, as well as a method of stripping photoresists using the solution. The stripping solution of the invention assures effective protection of Al, Cu and other wiring metal conductors against corroding as well as efficient stripping of the photoresist film, post-ashing residues such as modified photoresist film and metal depositions. It also assures efficient stripping of Si-based residues and effective protection of the substrate (particularly the reverse side of a Si substrate) from corroding.
US08697336B2 Composition for forming a developable bottom antireflective coating
The present invention provides a composition for forming a bottom anti-reflective coating, and also provides a photoresist pattern formation method employing that composition. The composition gives a bottom anti-reflective coating used in a lithographic process for manufacturing semiconductor devices, and the coating can be developed with a developing solution for photoresist. The composition contains a solvent, a polymer having a condensed polycyclic aromatic group, and a compound having a maleimide derivative or a maleic anhydride derivative. The composition may further contain a photo acid generator or a crosslinking agent.
US08697335B2 Radiation-sensitive resin composition and compound
A radiation-sensitive resin composition includes a compound, a resin and a radiation-sensitive acid generator. The compound has a structure in which a group represented by a following formula (1) is bound to a nitrogen atom. The resin has an acid-dissociative dissolution-controlling group and has a property such that alkali solubility of the resin increases by an action of an acid. In the formula (1), Y is a monovalent group having 5 to 20 carbon atoms, and “*” represents a bonding hand with the nitrogen atom. In the formula (i), R1, R2 and R3 each independently represent a linear or branched alkyl group having 1 to 4 carbon atoms or a monovalent alicyclic hydrocarbon group having 4 to 12 carbon atoms, or R1 and R2 are linked with each other to form a bivalent alicyclic hydrocarbon group, and “*” represents a bonding hand with the oxygen atom.
US08697334B2 Miniaturized microparticles
An encoded microparticle having a spatial code is provided; and a set of encoded microparticles possessing subsets each provided with a distinguishable spatial code, wherein the codes comply with a pre-determined coding scheme. Presented are also methods of using the encoded microparticles in various biological assays, such as various multiplex assays and visualizing them by creating a digital image of the encoded microparticles and determining whether false positives are present. Further are provided methods of manufacture of the encoded microparticles which employ ferromagnetic nanoparticles applied using spin-on-glass techniques.
US08697333B2 Photocurable resin composition, dry film thereof, pattern forming method, and electrical/electronic part protective film
A photocurable composition includes: (A) an epoxy group-containing polymer compound having repeating units represented by the following formula (1), where R1 to R4 are each a hydrocarbon group, m is an integer of 1 to 100, a, b, c and d are each 0 or a positive number, such that 0<(c+d)/(a+b+c+d)≦1.0, and X and Y are each the formula (2) or (3), provided that at least one group of the formula (3) is present, (B) a photoacid generator represented by the formula (8)  and (C) a solvent.
US08697329B2 Positive resist composition and pattern forming method using the same
A positive resist composition, which comprises: (A) a resin of which solubility in an alkali developer increases under an action of an acid; (B) a compound capable of generating an acid upon irradiation with actinic rays or radiation; (C) a resin having at least one of a fluorine atom and a silicon atom; and (D) a solvent, wherein the resin (C) contains at least one of: (C1) a resin having at least one of a fluorine atom and a silicon atom and having an alicyclic structure; and (C2) a resin containing a repeating unit having at least one of a fluorine atom and a silicon atom in a side chain and a repeating unit having an unsubstituted alkyl group in a side chain; and a pattern forming method.
US08697327B2 Toner production process and toner
A process for producing a core-shell toner is provided in which the toner has core particles containing at least a binder resin (1), a colorant and a release agent and shell layers which contain at least a resin (2) and with which the core particles are covered; and the process including the steps of (A) mixing a binder resin-(1) dispersion, a colorant dispersion and a release agent dispersion, (B) adding to a mixed dispersion thus obtained an agglomerating agent to effect agglomeration, (C) adding to core agglomerated particles thus formed a mixture prepared by mixing the resin-(2) dispersion and a metal salt to make the resin (2) adhere to the surfaces of the core agglomerated particles, and (D) heating core-shell agglomerated particles thus formed to a temperature not lower than the glass transition temperatures of the binder resin (1) and resin (2) to effect fusion thereof.
US08697326B2 Method of manufacturing a carrier, a carrier, a development agent, and a process cartridge
A method of manufacturing a carrier including covering a core material with a covering material to form a covering layer on the core material and baking the covering material by heating the core material by high frequency induction applied thereto by a high frequency induction heating device.
US08697325B2 Carrier core material for electrophotographic developer and method for producing the same, carrier for electrophotographic developer, and electrophotographic developer
To provide a carrier for an electrophotographic developer in which high image quality and full colorization are possible while carrier scattering is reduced, and a method for producing the carrier, and an electrophotographic developer including the carrier. A carrier core material for an electrophotographic developer is produced so that the half-value width B of a peak having a maximum intensity in an XRD pattern satisfies B≦0.160 (degree). A carrier for an electrophotographic developer and an electrophotographic developer are produced from the carrier core material for an electrophotographic developer.
US08697320B2 Phenol compounds and positive photosensitive resin composition including the same
Disclosed are a novel phenol compound comprising a compound represented by Chemical Formula 1, a compound represented by Chemical Formula 2, or a combination thereof, and a positive photosensitive resin composition including the same.
US08697315B2 Photomask blank and production method thereof, and photomask production method, and semiconductor device production method
A photomask blank which is capable of preventing static buildup caused by electron beam pattern drawing for forming a resist pattern. The photomask blank provides a good pattern accuracy through optimization of the dry etching rate along the depth direction of the shielding film, and is capable of reducing the dry etching time by increasing the dry etching rate of the shielding film. The photomask blank includes a translucent substrate having thereon a shielding film composed mainly of chromium and the shielding film contains hydrogen. The shielding film is formed in such a manner that the film formation rate of the layer at the surface side is lower than the film formation rate of the layer at the translucent substrate side of the shielding film. The dry etching rate of the shielding film is lower at the translucent substrate side than at the surface side.
US08697314B2 Method of producing volume hologram laminate
A method of producing a volume hologram laminate which can regenerate a hologram image in an arbitrary wavelength by a simple process. The method uses a volume hologram forming substrate which includes: a substrate, a volume hologram layer formed on the substrate and containing a photopolymerizable material, a resin layer, formed on the substrate so as to contact to the volume hologram layer, containing a resin and a polymerizable compound. The producing method includes processes of: a hologram recording process to record a volume hologram to the volume hologram layer, a substance transit process of transiting the polymerizable compound to the volume hologram layer, and an after-treatment process of polymerizing the polymerizable compound.
US08697313B2 Method for making a fuel cell from a solid oxide monolithic framework
The invention is a novel solid oxide fuel cell (SOFC) stack comprising individual bi-electrode supported fuel cells in which a thin electrolyte is supported between electrodes of essentially equal thickness. Individual cell units are made from graded pore ceramic tape that has been created by the freeze cast method followed by freeze drying. Each piece of graded pore tape later becomes a graded pore electrode scaffold that subsequent to sintering, is made into either an anode or a cathode by means of appropriate solution and thermal treatment means. Each cell unit is assembled by depositing of a thin coating of ion conducting ceramic material upon the side of each of two pieces of tape surface having the smallest pore openings, and then mating the coated surfaces to create an unsintered electrode scaffold pair sandwiching an electrolyte layer. The opposing major outer exposed surfaces of each cell unit is given a thin coating of electrically conductive ceramic, and multiple cell units are stacked, or built up by stacking of individual cell layers, to create an unsintered fuel cell stack. Ceramic or glass edge seals are installed to create flow channels for fuel and air. The cell stack with edge sealants is then sintered into a ceramic monolithic framework. Said solution and thermal treatments means convert the electrode scaffolds into anodes and cathodes. The thin layers of electrically conductive ceramic become the interconnects in the assembled stack.
US08697311B2 Arrangement for interconnecting electrochemical cells, a fuel cell assembly and method of manufacturing a fuel cell device
An arrangement for interconnecting electrochemical cells of the type having a membrane electrode assembly (MEA) interposed between an anode gas diffusion layer (208) and a cathode gas diffusion layer (210), and first and second current collectors coupled to said anode and cathode gas diffusion layers (GDL), respectively, wherein the first current collector extends from the anode side of one cell to the cathode side of an adjacent cell, and wherein the cell components are clamped together. The first current collector (206) which is in contact with the anode gas diffusion layer (GDL; 208) of a first electrochemical cell (200a) is configured to be connected to the cathode side of a second, adjacent electrochemical cell (200b) via an inert and electrically conductive member (204b), without being in electrochemical contact with the electrochemically active components of the adjacent cell.
US08697308B2 Solid oxide electrolyte, solid oxide fuel cell including the solid oxide electrolyte, and method of preparing the solid oxide electrolyte
A solid oxide electrolyte including an oxide represented by Formula 1: (1−a−b)(Ce1-xMaxO2-δ)+a(Mb)+b(Mc)  Formula 1 wherein 0
US08697307B2 Solid oxide fuel cell stack
A solid oxide fuel cell stack includes a cell array in which M interconnector unit solid oxide fuel cells are connected in parallel to form a bundle, and N bundles are connected in series; a first plate-shaped current collecting member connected to a first bundle of the N bundles, the first current collecting member including a first terminal, and a second plate-shaped current collecting member connected to an Nth bundle of the N bundles, the second current collecting member including a second terminal; and a first elastic insulating member adjacent to the first current collecting member, the first insulating member having a first opening, a second elastic insulating member adjacent to the second current collecting member, the second insulating member having another first opening, and the first terminal passes through the first opening and the second terminal portion through the other first opening.
US08697306B2 Electrolyte electrode assembly and method for producing the same
Plural columnar recesses are formed in a depressed form, on one end surface of a solid electrolyte disposed on a side facing an anode. Accordingly, the solid electrolyte is formed with a thick-walled portion and thin-walled portions, wherein the thick-walled portion extends from an abutment surface with respect to the anode to an abutment surface with respect to a cathode. The thin-walled portions extend from the abutment surface with respect to the cathode to the columnar recesses, and further have a thickness smaller than that of the thick-walled portion. Therefore, the anode also is formed on bottom and side wall surfaces of the columnar recesses. In the obtained electrolyte electrode assembly, a calculated value of conductance per unit area is set at 2 to 30 S/cm2.
US08697303B2 Optimized cathode fill strategy for fuel cell
A method for controlling cathode air flow at system start-up by controlling a stack by-pass valve. The method includes determining a concentration of hydrogen in a cathode side of the fuel cell stack. The method also includes determining a volumetric flow rate through a cathode compressor, determining a volumetric flow rate through the cathode side and determining a fraction of volumetric flow rate through the cathode side to the total flow through the compressor. The method determines a modeled hydrogen outlet concentration from the fuel cell stack based on the volumetric flow rate through the compressor, the fraction of volumetric flow rate through the compressor to the total flow through the compressor and the concentration of hydrogen in the cathode side. The method uses a desired fraction of volumetric flow rate through the cathode side and the total flow through the compressor to determine the position of the by-pass valve.
US08697301B2 Fuel cell using carbon nanotubes
A fuel cell comprises an anode, a cathode, and a proton exchange membrane. The anode and cathode can include a catalyst layer which includes a plurality of generally aligned carbon nanotubes. Methods of making a fuel cell are also disclosed.
US08697295B2 Nonaqueous electrolytic solution and nonaqueous electrolyte secondary battery
A nonaqueous electrolytic solution that can provide a high energy density nonaqueous electrolyte secondary battery having a high capacity, excellent storage characteristics, and excellent cycle characteristics and suppressing the decomposition of an electrolytic solution and the deterioration thereof when used in a high-temperature environment includes an electrolyte, a nonaqueous solvent, and a compound represented by general formula (1): wherein R1, R2, and R3 each independently represent a hydrogen atom, a cyano group, or an optionally halogen atom-substituted hydrocarbon group having 1 to 10 carbon atoms, with the proviso that R1 and R2 do not simultaneously represent hydrogen atoms.
US08697284B2 Negative electrode material for lithium ion batteries
A negative electrode material is provided for lithium ion batteries offering a high capacity and a long cycle life. It is an alloy material consisting essentially of Si, Al, M1, and M2 wherein M1 is a transition metal, and M2 is a metal element of Groups 4 and 5, and having an Si—Al-M1-M2 alloy phase constituting fine crystal grains and an Si phase precipitating along crystal grain boundaries to form a network.
US08697277B2 Film-clad battery and method of producing film-clad battery
A joint section where covering films 2a, 2b of film-covered battery 1 are heat-sealed together is formed with flat surface 6′ having thickness t1 and groove 6 having thickness t2. Groove 6 serves to reduce the projection area of film-covered battery 1 by folding side 2c toward receiving section 2a1 with groove 6 serving as an edge, and groove 6 is made thinner than flat surface 6′ by Δt=t1−t2. Therefore, the length of covering films 2a, 2b produced on outer side 6a is shortened as compared with the case of folding the portion that has thickness t1.
US08697275B2 Rechargeable battery having an extendable case region
A battery including: a case having a case region extendable along a first direction; an electrode assembly housed within the case and including a first electrode, a second electrode, and a separator between the first electrode and the second electrode, the first electrode including a first uncoated region at a first end of the electrode assembly, and the second electrode including a second uncoated region at a second end of the electrode assembly, the second end facing oppositely away from the first end, and the first uncoated region being spatially separated from the second uncoated region along the first direction; and a terminal electrically coupled to at least one of the first uncoated region or the second uncoated region, the case region being between the first uncoated region and the second uncoated region along the first direction.
US08697274B2 Lithium ion battery
The present invention provides a lithium ion battery including a battery can, a battery cell received in the battery can, electrolyte filled in the battery can, and a battery cover sealing the battery can. The battery can is formed with a flange portion, and the battery cover is formed with a skirt portion corresponding to the flange portion. The skirt portion of the battery cover tightly wraps the flange portion of the battery can, and the skirt portion and the flange portion wrapped in the skirt portion are tightly wound and bent to the battery can, so as to realize desirable sealing between the battery can and the battery cover.
US08697272B2 Secondary battery having an insulating member
A rechargeable battery includes: an electrode assembly including: a positive electrode, a negative electrode and a separator between the positive electrode and the negative electrode that are wound together; a case housing the electrode assembly; a terminal electrically connected to the electrode assembly; and an insulating member installed between the electrode assembly and the case wherein the insulating member has a base and four insulating plates extending from the base.
US08697271B2 Molten salt and thermal battery
The present invention provides a molten salt containing at least two salts, and having a melting point of 350° C. or more and 430° C. or less and an electric conductivity at 500° C. of 2.2 S/cm or more. The present invention also provides a thermal battery including the molten salt as an electrolyte.
US08697270B2 Energy storage device
An energy storage device includes a housing, a plurality of battery packs in the housing, and a first set of fluid passages disposed between battery packs, the battery packs being thermally insulated from fluid in the fluid passages.
US08697264B2 Battery pack containing PCM employed with safety member
Disclosed herein is a battery pack including a battery cell having an electrode assembly of a cathode/separator/anode structure mounted in a battery case together with an electrolyte in a sealed state, and a protection circuit module (PCM) electrically connected to the battery cell, wherein the PCM is provided with a safety device of which a circuit is cut off when temperature is high or a large amount of current flows.
US08697263B2 Sheet with pulp fiber tangled around a magnetic material with spaced coatings
A sheet includes a pulp fiber and a linear magnetic material. The linear magnetic material has a substantially large Barkhausen effect. The linear magnetic material also has irregularities at an outer periphery of the linear magnetic material. The sheet in which the magnetic material is inhibited from being exposed at both surfaces of the sheet can be provided.
US08697261B2 Perpendicular magnetic recording medium
An object of the present invention is to increase an electromagnetic transducing characteristic (in particular, SNR) by further promoting separation and isolation of magnetic grains of a magnetic recording layer (122) in a perpendicular magnetic recording medium (100). Thus, a typical structure of the perpendicular magnetic recording medium (100) according to the present invention includes, on a substrate (110), at least a non-magnetic granular layer (120) having a granular structure in which a grain boundary part including one or a plurality of oxides is formed between non-magnetic grains each continuously grown in a columnar shape and a magnetic recording layer (122) formed continuously with the non-magnetic granular layer (120) and having a granular structure in which a grain boundary part including one or a plurality of oxides is formed between magnetic grains continuously grown in a columnar shape in this order, and at least one oxide included in the grain boundary part of the non-magnetic granular layer (120) and at least one oxide included in the grain boundary part of the magnetic recording layer (122) are oxides of a same composition.
US08697260B2 Method and manufacture process for exchange decoupled first magnetic layer
A perpendicular magnetic recording medium having a dual-layer magnetic film is disclosed. The bottom layer is completely exchange decoupled, and the top layer contains a certain amount of exchange coupling optimized for recording performance. Preferably, the bottom magnetic layer contains stable oxide material (for example, TiO2) and other non-magnetic elements (for example, Cr). A method of manufacturing the media is also disclosed.
US08697259B2 Boron carbide composite materials
The invention relates to a boron carbide composite material comprising diamond particles and boron carbide, the composite material having a porosity of less than 2 percent by volume. The invention further relates to a method for manufacturing such materials, the method including coating a plurality of diamond particles with boron carbide, combining the plurality of diamond particles to form a green body and subjecting the green body to a temperature in the range from about 1,200 degrees centigrade to about 2,000 degrees centigrade and pressure or vacuum not exceeding about 2,000 Mpa.
US08697256B2 Composition comprising phosphorescent compound and light emitting device using the composition
A composition comprising a phosphorescent compound, and a compound having a structure containing three or more repeating units having a dipole moment dimension of 1.0 Debye or more connected in series, wherein, based on the total number of dimer structures composed of any two repeating units connected in series contained in the above-described structure, the proportion of the number of dimer structures in which the dimension D2 of the dipole moment of the dimer structure, the dimension D1a of the dipole moment of the first repeating unit constituting the dimer structure and the dimension D1b of the dipole moment of the second repeating unit constituting the dimer structure satisfy a relation represented by the following formula (A): D1a
US08697252B2 High-strength hot-dip galvannealed steel sheet with superior phosphatability
Disclosed is a hot-dip galvannealed steel sheet that stably exhibits satisfactory phosphatability. It is a high-strength hot-dip galvannealed steel sheet which includes a base steel sheet and, arranged on at least one side thereof, an Fe—Zn alloyed galvanized layer. The base steel sheet contains 0.03% to 0.3% of carbon, 0.5% to 3.0% of silicon, and 0.5% to 3.5% of manganese, with the remainder including iron and inevitable impurities. The Fe—Zn alloyed galvanized layer has a concentration of silicon present as an oxide of [Si] (percent by mass) and a concentration of manganese present as an oxide of [Mn] (percent by mass), and these parameters satisfy the following conditions (1) and (2): [Si]≦0.25  (1) [Mn]/[Si]≦3.0  (2).
US08697251B2 Protective coating for metal surfaces
A coating for a metal surface that provides excellent resistance to both electrochemical corrosion and mechanical insult is provided. The coating involves at least an inner coating that is a sacrificial anodic layer and an outer coating that is a protective dielectric material made of inorganic metal oxide. Some versions of the coating include an intermediate layer as well that serves to improve adhesion between the coatings and may provide additional galvanic protection. Although the coating can be made by a variety of methods, advanced methods of spray application are provided for making high-quality lightweight versions the coating.
US08697248B2 Functionally graded metal matrix composite sheet
The present invention discloses an aluminum alloy product having a first outer layer, a central layer, and a second outer layer. The central layer of the aluminum alloy product has a higher concentration of particulate matter than said first or second outer layers. The particular matter has a size of at least about 30 microns. And, the aluminum alloy product has a thickness ranging from between about 0.004 inches to about 0.25 inches.
US08697238B2 Biomaterial, joint prosthesis using the biomaterial and method of producing the same
The object of the present invention is to provide a joint prosthesis, bearing material and a production method thereof, which suppresses wear in a sliding section and suppresses the production of abrasive powder even during repeated daily operation. To achieve the object, there is provided a biomaterial comprising: a substrate made of metal, alloy or ceramic; and a biocompatible material layer laminated on the substrate, wherein hydroxyl groups are formed on the substrate by surface-treating, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer which is combined with the hydroxyl groups of the substrate and with the biocompatible material layer.
US08697237B2 Thermosetting resin composition, method of manufacturing the same and circuit board
The invention relates to a thermosetting resin composition which includes a metal filler component, a fluxing component and a thermosetting resin binder. The metal filler component includes at least one of bismuth (Bi) and indium (In), and tin (Sn). The fluxing component, which at least one of a compound of structural formula (1) below and a compound of structural formula (2) below, is used. In the above formulas, R1 to R6 are each a hydrogen or alkyl group, and X is an organic group which has a lone electron pair or double bond π electrons and is capable of coordinating with a metal.
US08697235B2 Barrier laminate and gas barrier film using the same
Disclosed is a barrier laminate excellent in adhesiveness. The barrier laminate comprises a first organic layer, an inorganic layer, a second organic layer adjacent to the inorganic layer, and an adhesive layer adjacent to the second organic layer in that order, wherein the second organic layer is obtained by curing a polymerizable composition comprising a (meth)acrylate compound comprising a hydroxyl group at a terminal of the compound; and the adhesive layer comprises an epoxy series adhesive.
US08697234B2 Self-assembled monolayers and method of production
The invention relates to a self-assembled monolayer comprising fluoroalkyl chains F3C—(CF2)m—(CH2)n— of differing length, wherein m is an integer of from 3 to 36, n is an integer of from 0 to 40, and m in the longer fluoroalkyl chain is larger than m in the shorter fluoroalkyl chain by at least 2, preferably by at least 8. The molar ratio of the longer fluoroalkyl chains to the shorter fluoroalkyl chains is from 1:9 to 9:1.
US08697232B2 Pressureless expansion by means of superheated steam
In order to provide an economical process for applying a coating to at least one side, optionally to both sides, of a leather, in which gentle processing of the leather is ensured and hardening thereof is avoided, an aqueous plastic dispersion having compact particles containing a blowing agent being applied to this side or these sides and being allowed to solidify, and hollow microspheres being formed from the thermoplastic compact particles by supplying heat, the invention proposes that, after solidification, the plastic dispersion containing the compact particles is subjected to the action of expanded superheated steam at a temperature between 80° C. and 100° C. (FIG. 2).
US08697231B2 Porous structure having a controlled pattern, repeated in space, for producing surgical implants
The present invention relates to a porous structure having a controlled pattern (1), which is repeated in space, in three dimensions, said porous structure enabling the production of surgical implants for filling in bone defects. According to the invention, said structure is characterized in that said pattern (1) consists of three wings (2) arranged in a star shape, each angle (A) formed between two wings being substantially equal to 120°, each wing having a generally rectangular shape and being hollowed (3) at the center thereof. Each of the three wings (2) of said pattern is advantageously beveled at its free end or tip (4), and the width of the base (5) of each bevel is slightly greater than the thickness of the wings (2) of which it forms an extension.
US08697228B2 Carrier for glass substrates
A carrier (31) for a thin glass sheet (7) is disclosed. The carrier includes an elastomer (9) which has first (15) and second (17) opposed surfaces and a support (11) bonded to the first surface (15) of the elastomer (9). During use, the thin glass sheet (7) directly contacts and is releasably bonded to the elastomer's second surface (17). In order to provide a strong, yet releasable bond to the thin glass sheet (7), the elastomer's second surface (17) has a Shore A hardness in the range of 10-90 and a roughness less than or equal to 185 nanometers. In this way, the carrier/glass sheet assembly (13) is able to withstand the conditions encountered during manufacture of electronic components on the exposed surface (23) of the thin glass sheet (7).
US08697227B2 Weather-resistant multilayer systems
The invention relates to a multilayer product comprising a first layer (A), a second layer (B), a third layer (C), and a fourth layer (D). The first layer (A) is a scratch-resistant protective layer having a minimum extinction of 0.3 at 340 nm, the second layer (B) is an alkyl acrylate layer having a minimum extinction of 2 at 340 nm, and the third layer (C) and the fourth layer (D) contain a UV-stabilized polycarbonate. The invention also relates to a method for manufacturing the multilayer product.
US08697226B2 Door skin, a method of etching a plate for forming a wood grain pattern in the door skin, and an etched plate formed therefrom
The present invention is directed to a door skin having an exterior surface with an woodgrain pattern formed therein, and an etched plate for use as an embossing plate or with a molded die set, for forming the woodgrain pattern in the door skin. The exterior surface has outer portions lying on a first plane, spaced grooves recessed from the plane of the outer portions, and halftone portions. The halftone portions have spaced protrusions defined by channels, wherein the channels are recessed from the plane of the outer portions.
US08697223B2 Vapor-permeable laminate
A vapor-permeable laminate (1) with at least one first outer layer (2) and at least one second outer layer (3), the outer layers (2, 3) having perforations (4, 5) and being joined to one another in such a way that the perforations of the first outer layer (2) do not coincide with the perforations (5) of the second outer layer (3), and a structure (6) having pores (7) being provided between the outer layers (2, 3). In order to achieve sufficient vapor permeability with at the same time sufficient hydrostatic seal-tightness, it is provided that each of the pores (7) has a clear cross-sectional area (A) of less than 200 μm2.
US08697221B2 Plastic composite panel with the appearance and texture similar to natural lumbers
Disclosed herein is a wood plastic composite panel made of a resin composite in which wood fiber having a size of 80 to 300 meshes is included in a synthetic resin matrix, the wood plastic composite panel being provided at the entire surface thereof with an embossed structure of a lumber cut-open pattern having an average depth of 200 to 900 μm and a linear micro concavo-convex structure having an average depth of 10 to 500 μm, the panel having a reflection rate of 10 to 50% when light is incident on the surface of the panel at an incidence angle of 60 degrees. The wood plastic composite panel according to the present invention has excellent strength and durability. Furthermore, the wood plastic composite panel according to the present invention exhibits excellent appearance and texture comparable with cut-open surfaces of natural lumbers although the panel has a surface structure different from the cut-open surfaces of the natural lumbers.
US08697213B2 Photodegradable plastics material and its use
A photodegradable plastic is described, comprising cellulose esters and also, if appropriate, additives. A particular characterizing feature of this photodegradable plastic is that it comprises a dispersed photocatalytic carbon-modified titanium dioxide. Comparative experiments show that this photodegradable plastic exhibits a surprisingly high increase in photocatalytic degradability when compared with products in which a conventional or other modified titanium dioxide is used. This improvement is apparent in particular in use of the photodegradable plastic according to the invention when it is further processed to give moldings. The photodegradable plastic can, for example, first be further processed to give a filter tow. This can be used to produce filter rods, and these can then be used to produce filter plugs for filter-tip cigarettes.
US08697210B2 Polymer having polycyclic groups and coating compositions thereof
A polymer and coating composition containing the polymer are provided that are useful in coating applications such as, for example, food or beverage packaging containers. The polymer preferably includes a backbone having one or more polycyclic groups. In one embodiment, the polymer is a polyester and, more preferably, a polyester-urethane polymer. In one embodiment, the one or more polycyclic groups is a tricyclic or higher group.
US08697206B2 Cardboard and a method of manufacture thereof
The invention relates to cardboard used in authenticity products, comprising a fiber matrix having two surfaces, whereby the second surface of the fiber layer has a layer of surface sizing containing a marking agent in a particle form, its particle size being smaller than 50 μm. By incorporating the marking agent into the surface sizing, the particles of the marking agent can be attached to the board, at the same time decreasing their total consumption by 80 to 90% compared with a case where they would be added to pulp. By using particles of a size less than 50 μm, a top free from streaks and roughness can be formed, which streaks might otherwise weaken the quality of the product.
US08697199B2 Calamitic mesogenic compounds
The invention relates to novel calamitic mesogenic compounds which are especially suitable for use in birefringent films with negative optical dispersion, to novel liquid crystal (LC) formulations and polymer films comprising them, and to the use of the compounds, formulations and films in optical, electrooptical, electronic, semiconducting or luminescent components or devices.
US08697198B2 Magnetic field assisted deposition
Embodiments relate to applying a magnetic field across the paths of injected polar precursor molecules to cause spiral movement of the precursor molecules relative to the surface of a substrate. When the polar precursor molecules arrive at the surface of the substrate, the polar precursor molecules make lateral movements on the surface due to their inertia. Such lateral movements of the polar precursor molecules increase the chance that the molecules would find and settle at sites (e.g., nucleation sites, broken bonds and stepped surface locations) or react on the surface of the substrate. Due to the increased chance of absorption or reaction of the polar precursor molecules, the injection time or injection iterations may be reduced.
US08697197B2 Methods for plasma processing
Apparatus and method for plasma-based processing well suited for deposition, etching, or treatment of semiconductor, conductor or insulating films. Plasma generating units include one or more elongated electrodes on the processing side of a substrate and a neutral electrode proximate the opposite side of the substrate. Gases may be injected proximate a powered electrode which break down electrically and produce activated species that flow toward the substrate area. This gas then flows into an extended process region between powered electrodes and substrate, providing controlled and continuous reactivity with the substrate at high rates with efficient utilization of reactant feedstock. Gases are exhausted via passages between powered electrodes or electrode and divider.
US08697195B2 Method for forming a protective coating with enhanced adhesion between layers
A method for forming a protective coating on a substrate comprising, applying a bond coating to the substrate, the bond coating having a first surface roughness, ionizing an inert gas which flows into the surface of the bond coating so as to impart a second surface roughness to the bond coating greater than the first surface roughness, wherein the inert gas is ionized and caused to flow into the surface of the bond coating by a reverse polarity current supplied to an electrode which removes at least one electron from the inert gas, and applying a top coating to the bond coating. Additionally, a method for preparing a surface to receive and adhere to a coating comprising roughening the surface to create a micro-roughening network on the surface. In addition, a method of improving strain tolerance and cyclic spallation life of a protective coating.
US08697194B2 Curable overcoat compositions
A substantially colorless radiation overcoat composition suitable for overcoating ink-based images and xerographic-based images. The overcoat composition comprises at least one gellant, at least one monomer, at least one substantially non-yellowing photoinitiator, optionally a curable wax, and optionally a surfactant.
US08697193B2 Process and apparatus for coating a porous substrate with a coating liquid
An engagement head for engaging a porous substrate includes at least two pin sets, each pin set including a plurality of pins arranged in a plurality of parallel pin rows at a predetermined pin angle, wherein pins of immediately neighboring pin rows are arranged such that pin angles for the pins in a pin row are inversely symmetrical to pin angles for the pins in a neighboring pin row. The pins of a pin row move collectively in the same direction when a pin set is extended, which direction is determined by the pin angle of the pin row, whereby neighboring pin rows move in opposite longitudinal directions from one another when the pin set is extended. The pin sets may be extended and retracted in unison by a single actuation source.
US08697192B2 Low weight and high durability soft body armor composite using silicone-based topical treatments
Ballistic resistant articles having abrasion resistance. Particularly, abrasion resistant, ballistic resistant articles and composites having a silicone-based topical treatment.
US08697191B2 Process for coating a support surface with a porous metal-organic framework
Described is a process for coating at least part of a surface of a support with a porous metal-organic framework comprising at least one at least bidentate organic compound coordinated to at least one metal ion, which process comprises the steps (a) spraying of the at least one part of the support surface with a first solution comprising the at least one metal ion; (b) spraying of the at least one part of the support surface with a second solution comprising the at least one at least bidentate organic compound, wherein step (b) is carried out before, after or simultaneously with step (a), to form a layer of the porous metal-organic framework.
US08697186B2 Method for manufacturing a mask having submillimetric apertures for a submillimetric electrically conductive grid, and mask and submillimetric electrically conductive grid
A process for manufacturing a mask having submillimetric openings, in which: for a masking layer, a first solution of colloidal nanoparticles in a first solvent is deposited, the particles having a given glass transition temperature Tg, the drying of the masking layer, known as the first masking layer, is carried out at a temperature below said temperature Tg until a mask having a two-dimensional network of substantially straight-edged submillimetric openings, that defines a mask zone known as a network mask zone is obtained, a solid mask zone is formed by a liquid deposition, on the face, of a second masking zone, the solid mask zone being adjacent to and in contact with the network mask zone, and/or at least one cover zone is formed, the cover zone being in contact with the network mask zone, and/or after the drying of the first masking layer, a filled mask zone is formed by filling, via a liquid route, openings of a portion of the network mask zone. The invention also relates to the mask and the electroconductive grid obtained.
US08697182B2 Synthetic binder essentially made of materials from renewable resources, in particular of vegetable origin, and applications thereof in road engineering
The invention relates to a synthetic binder characterized in that said binder includes: from 20 wt % to 100 wt % of at least one polyester based essentially on material from renewable resources, in particular of vegetable origin, having: a hydroxyl number below 100 mg KOH/g, an acid number below 25 mg KOH/g, an iodine number below 100 g I2/100 g, and from 0 wt % to 80 wt % of at least one natural or modified resin from renewable resources, in particular of vegetable origin.
US08697175B2 Endoluminal device for in vivo delivery of bioactive agents
The present invention consists of an implantable structural element for in vivo delivery of bioactive active agents to a situs in a body. The implantable structural element may be configured as an implantable prosthesis, such as an endoluminal stent, cardiac valve, osteal implant or the like, which serves a dual function of being prosthetic and a carrier for a bioactive agent. Alternatively, the implantable structural element may simply be an implantable article that serves the single function of acting as a time-release carrier for the bioactive agent.
US08697167B2 Process for preparing solidified maltitol and its use in food and pharma products
The present invention relates to a process for preparing solidified maltitol. The solidified maltitol is prepared by turbulating a maltitol powder with gas and contacting it with a maltitol containing syrup wherein the quantity of the powder is ≧the quantity of the syrup. The solidified maltitol has superior properties in bakery products. It is further suitable in other food products such as confectionery, chewing gum coatings and tablets.
US08697165B2 Process for producing edible oil
The present invention provides means of allowing an edible oil to contain useful components derived from an oil-containing raw material, such as polyphenols, efficiently. The present invention is a process for producing an edible oil, wherein when the edible oil is expressed from an oil-containing raw material, a diacylglycerol-containing oil or fat is added to the oil-containing raw material so that the diacylglycerol content in the oil or fat obtained after the oil expression is 4% by weight or more.
US08697163B2 Reduction of sorbic acid precipitation by forming microemulsion
A method for reducing sorbic acid precipitation during manufacture and storage of stable preserved syrup. A microemulsion of a sorbic acid compound, a non-aqueous solvent, and a surfactant is made in water. Syrup ingredients are added to a bulk quantity of liquid, and the microemulsion is added to the liquid.
US08697162B2 Gassed beverages
Container containing a gassed acidulated beverage capable of producing a foam when the container is opened and the beverage poured. The beverage contains an additive which reduces the rate of release of the gas from the beverage when the container has been opened, without the beverage being poured. The additive has one or more of the following: an HLB value in the range 7-16; a molecular weight in the range 200-3000; and it is present in an amount of from 0.01 to 100 mg/l.
US08697158B2 Mineral amino acid polysaccharide complex
This document provides complexes comprising a mineral-amino acid compound and a polysaccharide. For example, the document provides compositions containing such complexes and methods of making and using such complexes.
US08697157B2 Meal replacement beverage
Meal replacement compositions are described herein. The meal replacement compositions are made using all natural ingredients and includes relatively high amounts of fiber and protein and relatively low amounts of fat. In some instances, a single serving of a meal replacement composition includes high amounts of cocoa, an ingredient containing plant polyphenols.
US08697144B2 Soluble canola protein isolate production (“nutratein”)
Canola protein isolates are provided which contain both albumin and globulin protein fractions that are soluble and parent in an acidic aqueous environment. The canola protein isolates are completely soluble in water at low pH, low in phytic acid and useful in products for human consumption, pet foods and aquaculture.
US08697143B2 Heat activated durable styling compositions comprising saccharide type compounds and film forming agents
A composition for durable non-permanent shaping or durable retention of a non-permanent shape of least one keratinous fiber comprising: (a) at least one film forming agent; and (b) at least one saccharide type compound chosen from C3 to C5 monosaccharides, optionally substituted with at least one C1 to C22 carbon chain, and compounds comprising at least one C5 to C7 saccharide unit substituted with at least one amino group.
US08697142B2 Calcium carbonate granulation
Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
US08697141B2 Method and composition for preventing and healing osteonecrosis of the jaw
A method and composition for preventing and treating all forms of osteonecrosis of the jaw are disclosed. The composition is comprised of 0.005%-2.0% weight/volume (w/v) chlorine dioxide source, such as sodium chlorite, chlorite ion, stabilized chlorine dioxide or similar and may take the form of a paste, gel, rinse, spray, powder, varnish or similar. The method for treatment and prevention includes the application of the composition in the oral cavity and other body areas affected by osteonecrosis of the jaw.
US08697139B2 Method of intervertebral disc treatment using articular chondrocyte cells
Harvesting articular chondrocyte cells from a non-critical location of a patient and growing additional cells for transplantation into a damaged or diseased disc of the patient.
US08697138B2 Methods of using krill oil to treat risk factors for cardiovascular, metabolic, and inflammatory disorders
This invention discloses methods of using krill oil and compositions comprising krill oil to treat risk factors for metabolic, cardiovascular, and inflammatory disorders. The present invention also relates to methods of using compositions comprising krill oil to modulate biological processes selected from the group consisting of glucose metabolism, lipid biosynthesis, fatty acid metabolism, cholesterol biosynthesis, and the mitochondrial respiratory chain. The present invention further includes pharmaceutical and/or nutraceutical formulations made from krill oil, methods of making such formulations, and methods of administering them to treat risk factors for metabolic, cardiovascular, and inflammatory disorders.
US08697135B2 Method for the preparation of a pharmaceutical composition comprising 5-aminosalicylic acid for use in treatment of ulcerative colitis and Crohn's disease
The present invention concerns a new method of preparing granules comprising 5-aminosalicylic acid and a new method of preparing a pharmaceutical composition for the treatment of ulcerative colitis or Crohn's disease by oral administration comprising as active ingredient 5-aminosalicylic acid.
US08697134B2 Facile route to the synthesis of resorcinarene nanocapsules
Described is a direct method for the fabrication of resorcinarene nanocapsules by photopolymerization of compounds of formula (I), such as resorcinarene tetraalkene tetrathiol (RTATT), in the absence of any template or preorganization. Further, by varying the polymerization media, a variety of other polymeric architectures like lattices, fibrous networks, and nanoparticles were obtained. The morphology and structure were characterized by transmission electron microscopy, energy dispersive spectroscopy, scanning electron microscopy, dynamic light scattering, infrared and nuclear magnetic resonance spectroscopy. These morphologically distinct resorcinarene polymeric architectures contain residual thiol and ene functional groups offering potential functionalization opportunities.
US08697133B2 Slow release compositions
The present invention relates to the provision of micron or sub-micron sized particles formed from one or more water-soluble crystals comprising a surface coating comprising one or more bioactive molecules wherein the particles are prepared such that in use the release of the bioactive molecule(s) is/are delayed and/or continually released over a period of time. Processes for the preparation of said particles, as well as the particles themselves are described, as well as uses of the particles.
US08697132B2 Capsule and powder formulations containing lanthanum compounds
The present invention includes an oral pharmaceutical capsule comprising a shell, lanthanum carbonate or lanthanum carbonate hydrate, and a lubricant such as talc, wherein the shell encapsulates the lanthanum carbonate or its hydrate and the lubricant. Capsule shells comprise, for example, gelatin. The present invention also includes an oral pharmaceutical powder comprising lanthanum carbonate or lanthanum carbonate hydrate and a pharmaceutically acceptable excipient. The oral pharmaceutical capsules and powders of the present invention can be administered to treat a patient at risk of or suffering from hyperphosphatemia, at risk of or suffering from chronic kidney disease (CKD), at risk of or suffering from soft tissue calcification associated with CKD, or at risk of or suffering from secondary hyperparathyroidism.
US08697131B2 Method for producing pharmaceutical drug particles of small particle size
Pharmaceutical drug particles of small particle size are produced by combining a solvent-non-solvent precipitate with an in-situ spray drying process. A pharmaceutical drug is dispersed in a water-miscible solvent, in particular ethanol, and heated in an infeed line under pressure to above the boiling point of the solvent until the drug dissolves. This solution collides as a fine liquid jet with a fine water jet in a gas-permeated microreactor, and the fine mist so arising vaporises rapidly. The organic solvent vaporizes first, then the water. The water may contain surface modifiers.
US08697128B2 Carbide-derived-carbon-based oxygen carriers
An oxygen delivery system is disclosed. The basis of the oxygen deliver system is a carbide-derived carbon (CDC). The CDC can be tuned to carry O2 directly (CDC OC), or hemoglobin can be adsorbed to provide a hemoglobin-based oxygen carrier (CDC HBOC). The delivery system allows the use of a variety of hemoglobins which differ in their oxygen dissociation profiles, including variant and mutant hemoglobins from other species. The delivery system is biocompatible and stable, and is able to irreversibly bind and hold large amounts of functional hemoglobin variants. The CDC HBOC and CDC OC provide a safe and effective blood substitute for combat casualty care, as well as being useful for oxygen delivery in other contexts.
US08697127B2 Method for preparing microspheres and microspheres produced thereby
The present invention relates to a method for preparing microspheres and microspheres prepared thereby, more particularly to a method for preparing a polymeric microsphere, including preparing an emulsion including a polymer compound, a drug, a water-insoluble organic solvent and a dispersion solvent and adding to the prepared emulsion a base or an acid to remove the water-insoluble organic solvent from the emulsion, a polymeric microsphere prepared thereby, and a composition for drug delivery including the microsphere. According to the present invention, a drug-containing polymer microsphere may be prepared quickly and simply without the solvent evaporation or solvent extraction process, thereby reducing water consumption and minimizing wastewater generation.
US08697126B2 Compositions for enternal application of microorganisms
The present invention describes a process for the manufacture of a solid composition comprising a microorganism, which process comprises a first step of blending and/or compacting the microorganism with a salt of a medium or long-chain fatty acid to prepare a powderous mixture or compacted granulate, and a second step of providing said powderous mixture or compacted granulate with a coating. The microorganisms are preferably probiotics. The invention also relates to the solid composition obtained by said process and to its use in food.
US08697123B2 Medication on the basis of 3,3′-diindolylmethane (DIM) with high-bioavailability and its use in treatment of human hyperplastic and inflammatory diseases
The invention relates to medicine and chemico-pharmaceutical industry. A medication for treating human hyperplastic and inflammatory diseases containing 3,3′-diindolylmethane as an active agent and a carrier containing a mixture of cod-liver oil and at least one polysorbate at the following proportions of the components in mass %: 3,3′-diindolylmethane 1-20 cod-liver oil10-20 polysorbatethe balance.
US08697118B2 Stabilizers for hemostatic products
A hemostatic product that includes a dextran support, at least one hemostatic agent and at least one hemostatic agent stabilizer. The at least one hemostatic agent is selected from the group consisting of thrombin and fibrinogen. The at least one hemostatic agent is associated with the dextran support. The at least one hemostatic agent stabilizer is associated with the at least one hemostatic agent.
US08697116B2 Pet food product and method of manufacture
A pet food is provided, comprising a sorbent food body and a fluid carrier comprising a functional ingredient absorbed into the body. The body preferably is relatively moist, having a moisture content for example of from 35% to 60% by weight and firm structure that is resilient under initial biting by a pet animal. Protein content is preferably at least 20% by weight. The sorptivity of the body is increased by depleting the body of a first liquid, for example by causing drying by exposure to a source of dry heat, such as in roasting, grilling, frying and baking. Methods of manufacture are disclosed including providing a sorptive food body, causing the body to take up a carrier fluid containing a functional ingredient and packing the body in suitable packaging. The invention further provides delivery means for delivering a functional ingredient to a pet animal, the delivery means comprising a sorbent food body with the functional ingredient absorbed therein. The functional ingredient may be a nutrient or a pharmaceutical.
US08697114B2 Medical implants with reservoir(s), and materials preparable from same
Described is a medically useful article comprising a three-dimensional body including one or more implantable substances, wherein the body defines one or more reservoirs for receiving amounts of a biocompatible wetting liquid. In certain embodiments the body is disruptable upon wetting with the biocompatible liquid to form a conformable implantable material such as a putty, paste or more flowable wetted implant material. Also described are methods for manufacturing such medical materials, and methods for using such medical materials to treat patients.
US08697109B2 Caged mercaptan and seleno-mercaptan compounds and methods of using them
Novel mercaptan compounds, particularly those including a photolabile protecting group, are described as well as methods of using the compounds for the prevention and treatment of ocular damage and disease.
US08697105B2 Injectable drug delivery formulation
The invention provides an injectable formulation that includes an active agent; a biocompatible solvent system, crosslinkable polymers such as polysaccharides; and crosslinking agents; wherein the formulation is substantially free of water. The invention also provides a drug delivery depot formed from the injectable formulation wherein the polymers crosslink in the presence of water in the body of a patient, or in the air, prior to implantation in the patient. Also provided are methods of treatment using such formulations and drug delivery systems.
US08697102B2 Compositions and methods for cell killing
A solid buffer including one or more ion exchange materials, wherein said solid buffer has a volumetric buffering capacity greater than about 20 mM H+/(L.pH unit) and further wherein, when said material is in an environment capable of transporting H+ ions, said solid buffer is adapted to cause the death of at least one target cell within or in contact with said environment. A selectively permeable barrier layer may be provided covering the solid buffer.
US08697099B2 Cosmetic treatment system and methods
A cosmetic treatment system is provided having ingredients that may prevent signs of aging, improve the aesthetic appearance of skin, and promote recovery from environmental stresses. The composition includes natural ingredients, including at least one ingredient or extract from rosemary; at least one ingredient or extract from Centella, Echinacea, Alpinia or mixtures thereof; a DNA repair enzyme; and at least one pharmaceutically or cosmetically acceptable vehicle. The treatment system may further include a patch for applying the cosmetic ingredients and/or a packaging system for holding the components of the cosmetic treatment system.
US08697094B2 Stable solid preparations
It is intended to provide a process for producing unstable amorphous benzimidazole compounds having a proton pump inhibitor function, and stable solid preparations for medicinal use containing these compounds which are produced by blending such an amorphous benzimidazole compound with a nontoxic base such as a basic inorganic salt, forming an intermediate coating layer on the layer containing the active ingredient and further forming an enteric coating layer or a release-controlling coating layer.
US08697090B2 Method of treating persistent genital arousal disorder with a neurotoxin
A method of controlling dysregulation of the dorsal cutaneous nerve of the clitoris and, in particular, a method for treating PGAD is provided. In one aspect, the method comprises administering a neurotoxin, such as a botulinum toxin, to the clitoral area of the human in need of treatment.
US08697088B2 VLPs derived from cells that do not express a viral matrix or core protein
The present invention discloses novel influenza virus-like particles (VLPs) that contain chimeric proteins or influenza membrane proteins. The chimeric proteins are derived from fragments of influenza membrane proteins fused to heterologous proteins. The invention includes antigenic formulations and vaccines comprising VLPs of the invention as well as methods of making and administering VLPs to vertebrates, including methods of inducing immunity to infections, such as influenza.
US08697087B2 Influenza vaccines including combinations of particulate adjuvants and immunopotentiators
Influenza vaccines containing insoluble particulate adjuvants have been found to elicit an IgG response that is primarily a TH2 response (IgG1). This response can be shifted towards a TH1 response (IgG2a) by including immunopotentiators in the compositions. Thus the invention provides an immunogenic composition comprising: (i) an influenza virus antigen; (ii) an insoluble particulate adjuvant; and (iii) a immunopotentiator.
US08697085B2 Group A Streptococcus multivalent vaccine
Immunogenic compositions are provided herein that are useful for inducing an immune response specific against group A streptococcus (GAS). Immunogenic compositions provided herein are multivalent and comprise a plurality of immunogenic peptides or fusion polypeptides comprising the immunogenic peptides that induce an immune response against GAS. The immunogenic compositions provided herein induce an immune response against the GAS serotypes represented by an immunogenic peptide (derived from an M protein or Spa protein) comprised within the immunogenic composition and also induce an immune response against serotypes that are unrepresented by any immunogenic peptide included in the immunogenic composition. Methods for using the compositions for inducing an immune response against GAS and for treating or reducing the likelihood of occurrence of a GAS infection are also provided.
US08697082B2 Prevention and treatment of synucleinopathic and amyloidogenic disease
The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
US08697079B2 IgE antibodies for the treatment of cancer
The present invention provides monoclonal IgE antibodies comprising Fc epsilon (ε) constant regions and variable regions comprising at least one antigen binding region specific for binding a single epitope of a circulating, tumor-associated antigen (TAA) that is not a cell surface antigen wherein the epitope of the targeted antigen is not highly repetitive or is a non-repetitive epitope. The IgE antibodies of the invention are useful in the treatment of cancer associated with the tumor antigen. In one embodiment the TAA is prostate-specific antigen (PSA).
US08697076B2 Antibodies selective for pathological tau dimers and prefibrillar pathological tau oligomers and their uses in treatment, diagnosis and monitoring of tauopathies
Antibodies selective for pathological tau dimers and/or prefibrillar pathological tau oligomers, immunogenic peptides and epitopes of these antibodies, hydridomas producing these antibodies, uses of these antibodies, immunogenic peptides and epitopes in preparation of pharmaceutical compositions for the treatment of tauopathies, and uses of these antibodies, immunogenic peptides, epitopes and pharmaceutical compositions in the treatment of tauopathies are described. Also described are uses of these antibodies, immunogenic peptides, epitopes in diagnosis and monitoring of tauopathies.
US08697074B2 Methods and compositions for enhanced delivery of macromolecules
The invention provides compositions and methods that enhance the delivery of large macromolecules (i.e., greater than 10 kDa), such as antigen-binding polypeptides, across tight junctions. Such methods and compositions are particularly useful for delivering therapeutic antigen-binding polypeptides to the CNS, via intranasal administration, for the treatment of neurological disorders.
US08697065B2 Non-natural ribonuclease conjugates as cytotoxic agents
The present invention is directed toward the delivery of a toxic protein to pathogenic cells, particularly cancer cells. In preferred embodiments, the toxic protein is a ribonuclease that has been modified to make it toxic to target cells and that can be conjugated to a target cell-specific delivery vector, such as an antibody, for delivery to pathogenic cells.
US08697062B2 Compositions and methods for ribonuclease-based therapeutics
The present invention relates generally to conjugates of human ribonucleases and water-soluble polymers, compositions comprising the conjugates and methods of using the same. In particular, the present invention provides conjugates of human ribonucleases and one or more water-soluble polymer compositions (e.g., to increase serum half-life and a pharmacokinetic profile, in vivo biological activity, stability, and/or reduce host immune response to the protein in vivo) as well as methods of using the conjugates in the therapy, treatment, and/or prevention of disease (e.g., cancer).
US08697061B2 Tumor specific oligosaccharide epitopes and use thereof
The present invention describes oligosaccharide sequences, which are specifically expressed by human tumors. The present invention is related to a method of determining an oligosaccharide sequence, which comprises a tumor specific terminal N-acetylglucosamine residue, in a biological sample, the presence of said sequence in said sample being an indication of the presence of cancer. The present invention provides antigenic substances comprising said oligosaccharide sequences in a polyvalent form and it further provides diagnostic agents, pharmaceutical compositions and cancer vaccines comprising said oligosaccharide sequences or substances binding to said oligosaccharide sequences. The present invention is also related to methods for the treatment of cancer.
US08697060B2 Treatment method for relapsing-remitting multiple sclerosis
Disclosed is a method for treating relapsing-remitting multiple sclerosis in a patient by administering to the patient autologous, ex vivo-expanded CD4+CD25+Foxp3+CD127low T reg cells when the patient is in remission. Also disclosed is a method of inhibiting the activity of autoimmune, autologous cytotoxic T and B cells in a patient suffering from relapsing-remitting multiple sclerosis, comprising administering a therapeutically effective amount of autologous CD4+CD25+Foxp3+CD127low T reg cells to the patient.
US08697059B2 Compositions and soft tissue replacement methods
The present specification discloses compositions and methods for use in breast augmentation procedures. The compositions include adipose tissue and compounds that upregulate both FGF-2 and VEGF, promote new blood vessel formation thereby reducing tissue volume loss and increasing survival rate of the adipose tissue when the composition is introduced into breast tissue.
US08697058B2 Cytocompatible alginate gels
The present invention relates to a method of making cytocompatible alginate gels and their use in the treatment of cardiomyopathy.
US08697056B2 Compositions and soft tissue replacement methods
The present specification discloses compositions and methods of transplanting tissue useful for treating a soft tissue condition of an individual.
US08697051B2 Composition comprising alkaline sphingomyelinase for use as a dietetic preparation, food supplement or pharmaceutical product
The invention relates to a composition which, depending on the user, may be taken as a nutritional, dietetic or strictly therapeutic preparation, comprising as its active substance alkaline sphingomyelinase which is capable of preventing or treating various pathological conditions including cancerous processes, inflammatory processes of the intestine, hypercholesterolaemia and infections with Helicobacter pylori.
US08697049B2 Modified bacteriophage including an alpha/beta small acid-soluble spore protein (SASP) gene
Provided is a modified bacteriophage capable of infecting a target bacterium, which bacteriophage includes an α/β small acid-soluble spore protein (SASP) gene encoding a SASP which is toxic to the target bacterium, wherein the SASP gene is under the control of a constitutive promoter which is foreign to the bacteriophage and the SASP gene.
US08697045B2 Pegylated interleukin-10
Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for preparing the same, are provided. The method produces a stable mono-pegylated IL-10, which retains IL-10 activity, where pegylation is selective for the N-terminus on one subunit of IL-10 with little or no formation of monomeric IL-10. The method also provides a substantially homogenous population of mono-PEG-IL-10.
US08697043B1 Odor suppression of volatile organic analgesic compounds and method of use
Disclosed are odor suppressing analgesic compositions comprising: a) from about 0.1% to about 20%, by weight, of farnesol or other suitable deodorizing bacteriostatic agent; and b) from about 0.1% to about 60%, by weight, volatile organic compound wherein said volatile organic compound may be encapsulated and is chosen from the following (menthol, camphor, methyl salicylate, methyl nicotiniate, or combination of thereof); and c) a water-in-oil or oil-in-water emulsion, gel, patch, plaster, ointment, solution or spray carrier. An optimized odor suppressing analgesic composition can provide a combination of antimicrobial properties, odor suppression properties, skin cooling or heating properties, topical analgesic properties, low irritation and stability.
US08697042B2 Organopolysiloxane and cosmetic containing it
The invention provides an organopolysiloxane shown by the following formula (1); such that each R1 independently represents a group selected from an alkyl group having 1 to 30 carbon atoms and optionally substituted with a fluorine atom, an aryl group having 6 to 30 carbon atoms, and an aralkyl group having 7 to 30 carbon atoms; each R2 independently represents a divalent organic group having 2 to 15 carbon atoms and optionally intervened with an oxygen atom; and each R3 independently represents a group selected from a polyoxyalkylene group shown by the following formula (2), —(C2H4O)a(C3H6O)b(C4H8O)c(C5H10O)dR4  (2) a hydrogen atom, and a group shown by the following formula (3), wherein at least one of R3 in one molecule is the polyoxyalkylene group shown by the formula (2) with “m” representing an integer of 0 to 300 and “n” representing an integer of 1 to 10.
US08697040B2 Hair treatment compositions
The present invention relates to hair treatment compositions and methods. More particularly, the invention relates to hair treatment compositions comprising lipids and creatine. The hair treatment compositions of the present invention may be used to improve the tensile properties of hair, such as hair elasticity and strength.
US08697037B2 Composition
The present invention provides a surfactant product in the form of a solid comprising a surfactant, sodium carbonate and cream of tartar.
US08697034B2 Hyperpolarized 89-yttrium and methods relating thereto
The present invention relates to the preparation of hyperpolarized 89Y. Hyperpolarized 89Y may be used as nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) agents for sensitive detection and imaging.
US08697033B2 Modified pyrazine derivatives and uses thereof
In some embodiments, the invention provides modified pyrazine derivatives containing a central pyrazine ring with two secondary amine groups attached directly to the central pyrazine ring and two amino carbonyl groups attached directly to the central pyrazine ring. The secondary amine groups are terminated by alkyl groups containing from 1 to 6 carbons. The amino carbonyl groups can be terminated by a wide range of substituents including, but not limited to, alkyl and alkylene groups, polyether groups, including poly(ethylene glycol) groups, secondary and tertiary amine groups, polyhydroxylated alkyl groups, amino carbonyl groups, amino thioketone groups, and combinations thereof. In some embodiments, the invention provides modified pyrazine derivatives useful as optical agents in a wide variety of biomedical imaging procedures, including diagnostic and imaging procedures. In an embodiment, for example, modified pyrazine derivatives are provided which are useful in monitoring organ and system functioning, for example in monitoring renal system functioning.
US08697027B2 Methods and systems of producing hydrogen and oxygen for power generation, and power source
Methods and systems of providing a source of hydrogen and oxygen with high volumetric energy density, as well as a power systems useful in non-air breathing engines such as those in, for example, submersible vehicles, is disclosed. A hydride reactor may be utilized in forming hydrogen from a metal hydride and a peroxide reactor may be utilized in forming oxygen from hydrogen peroxide. The high temperature hydrogen and oxygen may be converted to water using a solid oxide fuel cell, which serves as a power source. The power generation system may have an increased energy density in comparison to conventional batteries. Heat produced by exothermic reactions in the hydride reactor and the peroxide reactor may be transferred and utilized in other aspects of the power generation system. High temperature water produced during by the peroxide reactor may be used to fuel the hydride reactor.
US08697022B2 Method of making a trihalosilane
A method of making a trihalosilane comprising contacting an organotrihalosilane according to the formula RS1X3 (I), wherein R is C1-C10 hydrocarbyl and each X independently is halo, with hydrogen, wherein the mole ratio of the organotrihalosilane to hydrogen is from 0.009:1 to 1:2300, in the presence of a catalyst comprising a metal selected from (i) Re, (ii) a mixture comprising Re and at least one element selected from Pd, Ru, Mn, Cu, and Rh, (iii) a mixture comprising Ir and at least one element selected from Pd and Rh, (iv) Mn, (v) a mixture comprising Mn and Rh, (vi) Ag, (vii) Mg, and (viii) Rh at from 300 to 800° C. to form a trihalosilane.
US08697018B2 Reduction of oxides of nitrogen in a gas stream using molecular sieve SSZ-25
The invention relates generally to molecular sieve SSZ-25 and its use in the reduction of oxides of nitrogen in a gas stream such as the exhaust from an internal combustion engine.
US08697016B2 Reactor for carrying out autothermal gas-phase dehydrogenations
A reactor in the form of an essentially horizontal cylinder for carrying out an autothermal gas-phase dehydrogenation of a hydrocarbon-comprising gas stream by means of an oxygen-comprising gas stream to give a reaction gas mixture over a heterogeneous catalyst configured as monolith is disclosed herein. The interior of the reactor is divided by a detachable, cylindrical or prismatic housing which is arranged in the longitudinal direction of the reactor, gastight in the circumferential direction and open at two end faces of the housing into an inner region, having one or more catalytically active zones. In each case, a packing composed of monoliths may be stacked on top of one another, next to one another, and above one another and before each catalytically active zone. Also in each case, a mixing zone having solid internals and an outer region arranged coaxially to the inner region are provided.
US08697012B2 High-speed automatic dispensing device with replaceable dispensing head and dispensing station
A high-speed automatic dispensing apparatus capable of preparing samples under different conditions, minimizing waste liquid materials, and realizing high productivity. A dispensing station is also provided. The high-speed automatic dispensing apparatus with a replaceable dispensing head comprises a dispensing head including a plurality of pipettes, a pipette head to which one end of a plunger extending to pass through each pipette is fixed, and a head body part abutting against the pipette head and allowing the pipettes to pass therethrough, a pipette head moving mechanism vertically moving the pipette head, and a drive mechanism horizontally and vertically moving the dispensing head. The dispensing station includes the high-speed automatic dispensing apparatus.
US08697009B2 Microfluidic devices for fluid manipulation and analysis
The present invention relates to microfluidic devices and methods for manipulating and analyzing fluid samples. The disclosed microfluidic devices utilize a plurality of microfluidic channels, inlets, valves, filter, pumps, liquid barriers and other elements arranged in various configurations to manipulate the flow of a fluid sample in order to prepare such sample for analysis.
US08697005B2 Assemblies for multiplex assays
Multiplex binding assay assemblies are disclosed. The assemblies include at least one assay bar that has a top side, a bottom side, and at least one well accessible from the top side of the assay bar, with each well including a side surface, a bottom surface, an open top end. Each well also includes at least one secondary container, with each secondary container including a capillary tube that (i) begins at a location within an interior volume of the well and (ii) ends at a location beneath the bottom side of the assay bar. The assemblies further include a guiding track, which includes a set of two rails, with each rail having its own separate groove. Such grooves are configured to run parallel to each other with a distance between such grooves, with a first groove configured to receive a protruding element (or an end) of a first side of the assay bar, and a second groove configured to receive a protruding element (or an end) of a second side of the assay bar. The set of two separate grooves are configured to allow the assay bar to glide along the grooves from one side to a second side of the guiding track.
US08697004B2 Sequencing system with memory
The present teachings provide a device including a memory. According to various embodiments, the memory is readable, writable, and rewritable. The present teachings further provide processing stations, e.g., for carrying out electrophoresis, per, genetic analysis, sample preparation, and/or sample cleanup, etc., that are capable of reading from and/or writing/rewriting to such memory.
US08697002B2 Latch for a hydroprocessing vessel and method relating thereto
One exemplary embodiment may be a latch for a hydroprocessing vessel. The latch may include an elongated substantially cylindrical shaft, a helical pawl coupled to the elongated substantially cylindrical shaft, and a grip coupled to the elongated substantially cylindrical shaft. Usually, the grip forms a polygon having at least three sides and adapted to be engaged by a tool.
US08696996B2 Device and method for generating a barrier discharge in a gas flow
The invention relates to a device and method for generating a barrier discharge in a gas flow, comprising a reactor chamber permeable by the gas from an inflow side to an outflow side, a first electrode, a dielectric that shields the reactor chamber against the first electrode, and a second electrode, wherein the second and the first electrode can be switched to connect to a voltage source. To briefly expose a greater portion, preferably all, of the gas flow through the reactor chamber to a plasma, at least two discharge elements associated with the first electrode and made of electrically conductive material protrude at least partially into the reactor chamber and are electrically insulated from each other and the first and second electrodes, and the second electrode is disposed relative to the discharge elements such that discharges occur between the discharge elements and the second electrode in the reactor chamber.
US08696993B2 Method of raising temperature of received object, and analyzing device
The present invention relates to an analyzing apparatus (1) for analyzing a sample using a container (2) accommodating reagents sealed therein, while raising the temperature of the reagents up to a predetermined temperature. The analyzing apparatus (1) comprises a first temperature measuring means (31) for measuring temperature of the container (2), a second temperature measuring means (32) for measuring temperature around the container (2), a heater (4) for supplying heat energy to the container (2), and a controller for controlling the heater (4) based on a measurement result at the first and second measuring means (31, 32).
US08696989B2 Calorimeter sensor
A calorimeter device includes various components located on a common substrate. A first (calorimeter) integrated chip device is located on the substrate. This first device has a first microfluidic channel that has first side and a second side. A first heat sensing circuit is located on the first side of the first channel and a second heat sensing circuit is located on the second side of the channel, opposite the first side and facing the first heat sensing circuit. A second integrated chip device is located on the substrate and proximal to the first device. The second device includes a second microfluidic channel having a third side and fourth side. A third heat sensing circuit is located on the third side of the second channel. A fourth heat sensing circuit is located on the fourth side of the channel, opposite the third side and facing the third heat sensing circuit.
US08696988B2 In situ heat induced antigen recovery and staining apparatus and method
An automated in situ heat induced antigen recovery and staining method and apparatus for treating a plurality of microscope slides. The process of heat induced antigen recovery and the process of staining the biological sample on the microscope slide are conducted in the same apparatus, wherein the microscope slides do not need to be physically removed from one apparatus to another. Each treatment step occurs within the same reaction compartment. The reaction conditions of each reaction compartment for treating a slide can preferably be controlled independently, including the individualized application of reagents to each slide and the individualized treatment of each slide.
US08696981B2 Apparatus and methods for disinfecting spaces
The instant invention provides methods and apparatus for disinfecting a space, e.g., a hospital room, using chlorine dioxide. One aspect of the invention provides an apparatus for disinfecting a space. The apparatus includes: a chlorine dioxide gas generator; a sensor adapted and configured to measure the relative pressure inside the space and outside the space; and a computer operatively connected to the sensor and the chlorine dioxide generator, the computer adapted and configured to control the chlorine dioxide generator to operate only when the space is under negative pressure as compared to outside the space. Another aspect of the invention provides a method of disinfecting a space. The method includes: setting an apparatus as described herein in the space; and allowing the apparatus to determine if the space is under negative pressure. If the space is under negative pressure, the apparatus generates chlorine dioxide gas to disinfect the space.
US08696979B2 Ni-base superalloy and method for producing the same
A Ni-base superalloy having a chemical composition comprising Al: 4.5-7.0 wt %, Ta+Nb+Ti: 0.1-4.0 wt %, with Ta being less than 4.0 wt %, Mo: 1.0-8.0 wt %, W: 0.0-10.0 wt %, Re: 2.0-8.0 wt %, Hf: 0.0-1.0 wt %, Cr: 2.0-10.0 wt %, Co: 0.0-15.0 wt %, Ru: 0.0-5.0 wt %, and the balance being Ni and unavoidable impurities, and a method for producing the same are disclosed. The Ni-base superalloy has excellent creep property at high temperature and is suitable for use as a member at high temperature under high stress.
US08696978B2 Elastically interconnected cooler compressed hearth and walls
An elastically interconnected cooler compressed hearth comprises a concave dished bottom lined with a sub-layer and a working layer of hearth bricks. Cylindrical walls that rise up from the rim of the concave dished bottom are constructed with one or more tiers of coolers shaped into arc segment blocks that are joined together by their flanges to form complete rings. The outer perimeter of the hearth brick within the ringed tiers is inwardly compressed toward the center to disallow any leaks from forming between the separate bricks. The coolers are elastically interconnected at their flanges by fasteners and springs. Each spring can be individually adjusted to obtain optimal working pressures on the whole of the core wall and hearth floor bricks.
US08696977B2 Device for the thermal deburring of workpieces
The invention relates to a device for the thermal deburring of workpieces, having at least one deburring chamber and one feeding device for introducing a fuel gas mixture into the deburring chamber. A supplementary gas supply is provided for at least the deburring chamber or for the feeding device such that the fuel gas mixture located at least in the deburring chamber or in the feeding device can be mixed at least partially with supplementary gas. Further, a method for the rapid ventilation of a device for the thermal deburring of workpieces is also provided.
US08696976B2 Method and devices for regulating the flow rate and for slowing down non-ferromagnetic, electrically-conducting liquids and melts
The invention relates to a method for regulating the flow rate and for slowing down non-ferromagnetic, electrically conducting liquids and melt streams through magnetic fields, in particular in the tapping of metallurgical containers such as blast furnaces and melt furnaces. The method is characterized in that the melt stream is routed in a closed routing element using at least one stationary magnetic field with a constant polarity, at least one stationary magnetic alternating field or using a multi-poled magnetic travelling field, in such a way that the magnetic field lines transversally penetrate the melt flow across the entire cross section thereof and such that a voltage is induced in the melt stream by the magnetic fields, there being eddy currents induced thereby in the melt stream that are disposed radially and axially when a stationary magnetic field of constant polarity is used and that are disposed axially when a stationary alternating magnetic field or electromagnetic travelling field is used, and that due to the interactions between the magnetic fields and the eddy currents forces are generated that can affect the flow rate of the melt stream.
US08696974B2 Adhesive composition, process for producing the same, molded objects, and process for producing heat-shrinkable tube
An adhesive composition comprising 100 parts by weight of a fluorine-containing polymer and 2 to 30 parts by weight of an unsaturated compound containing at least one polar group selected from the group consisting of an epoxy group and a carboxyl group, wherein the fluorine-containing polymer has been graft-modified with the polar group-containing unsaturated compound by irradiation of ionizing radiation, a production process thereof, and formed products such as a heat-shrinkable tube equipped with a layer composed of the adhesive composition.
US08696973B2 Nanofiber manufacturing apparatus and method of manufacturing nanofibers
A method of manufacturing nanofibers according to an aspect of the present invention by electrically stretching a solution in space and depositing the nanofibers in a given region includes: effusing the solution from an effusing body having an effusing hole which allows the solution to effuse in a direction; applying a given voltage between the effusing body and a charging electrode being conductive and disposed at a given distance from the effusing body, using a charging power supply configured to apply the given voltage; and determining a flight path of the solution and the nanofibers such that a length of the flight path of the solution and the nanofibers is longer than a shortest path length which is a length of a shortest imaginary path connecting an end opening of the effusing hole and an accumulation part on which the nanofibers are accumulated.
US08696972B2 Method for producing a cushion element, especially a seat cushion element for use in a motor vehicle, and cushion element
A cushion element for a vehicle seat has fibers and foam particles bound by a binder. A precursor material for the cushion element is made by independently adding the fibers and the foam particles together with the binder. The addition and ratio of the fibers and foam particles may depend on their location in the cushion element, and may be influenced by electrostatic discharge means.
US08696971B2 Method and system for layerwise production of a tangible object
A method cycle of a method for layerwise production of a tangible object (5) comprises the successive steps of: solidifying predetermined parts of a liquid so as to obtain a solid layer (14) having a predetermined shape; separating said solid layer from a construction shape (6); and moving, relative to one another, the separated solid layer and the construction shape to a predetermined position relative to one another. Solidifying is carried out such that the solid layer and the construction shape have nonmatching shapes in the sense that all surface portions of a solid layer side (70) that are or have been in contact with a liquid contacting side (11) of the construction shape can not simultaneously be brought in full contacting engagement with the liquid contacting side.
US08696966B2 Method of fabricating a wall structure
The present invention is directed to a method of fabricating a wall structure that comprises a polyurethane backing. In certain embodiments, no additional layer is coated onto or disposed on the polyurethane backing that is formed through the process disclosed herein.
US08696962B2 Methods for reducing defects in ceramic articles and precursors
A method of reducing the defects in ceramic articles and precursors, particularly ceramic articles and precursors made using a batch composition containing an oil phase material. The method includes increasing the concentration of a water insoluble soap in the batch composition, which can increase the cohesive strength of the oil phase, leading to a reduction in the incidence of defects in the ceramic articles and precursors.
US08696961B2 Method for forming an absorbent core
A method for forming an absorbent core. The method includes the steps of forming and compressing an absorbent core, followed by passing the absorbent core through a subsequent nip between two rolls. At least one of the rolls has a surface including an elastic material, such that the hard-spot number of the absorbent core is reduced. Also, a device for forming absorbent cores as well as absorbent cores produced using the method.
US08696958B1 Molded composite manufacturing process and products thereof
A manufacturing process is disclosed that allows molded planar products such as solid interior and entry doors to be produced by molding lignocellulosic and cellulosic composite materials. The doors can be manufactured by compressing and heating a layered mixture of fine wood particles blended with thermo-set molding resins and coarse wood particles blended with thermo-set binding resins between two open molds. The molded door is then removed from between the molds and trimmed to the finished size.
US08696955B2 Method of making polymer hollow particles with controllable holes in their surfaces
A method for making a hollow polymer particle having a single, substantially circular opening in its surface.
US08696950B2 Liquid crystal display device and method for manufacturing the same
A liquid crystal display device including an array of pixels each including first and second substrates, first and second electrodes formed on opposing surfaces of the first and second substrates, which surfaces are positioned opposite to the second and first substrates, first and second alignment restricting portions provided in the first and second electrodes, first and second alignment films covering respectively the first and second electrodes, the first and second alignment restricting portions, and the opposing surfaces of the first and second substrates, and a liquid crystal layer formed between the first and second alignment films and containing liquid crystal molecules, wherein, in each pixel, major axes of a group of liquid crystal molecules are positioned substantially in the same imaginary plane in a predetermined overlapped region between the first and second electrodes, and a pre-tilt is given to the liquid crystal molecules by at least the first alignment film.
US08696938B2 Supercritical fluid process for producing nano graphene platelets
The present invention provides a process for producing pristine or non-oxidized nano graphene platelets (NGPs) that are highly conductive. The process comprises: (i) subjecting a graphitic material to a supercritical fluid at a first temperature and a first pressure for a first period of time in a pressure vessel and then (ii) rapidly depressurizing the fluid at a fluid release rate sufficient for effecting exfoliation of the graphitic material to obtain the NGP material. Conductive NGPs can be used as a conductive additive in transparent electrodes for solar cells or flat panel displays (e.g., to replace expensive indium-tin oxide), battery and supercapacitor electrodes, and nanocomposite for electromagnetic wave interference (EMI) shielding and static charge dissipation, etc.
US08696936B2 System for controlled on demand in situ hydrogen generation using a recyclable liquid metal reagent, and method used in the system
A hydrogen generating system and a method of in situ hydrogen generation controlled on demand capable of reacting an aluminum-free metal reagent composed of at least one of alkali metals, alkaline earth metals, alkali metal alloys and blends including alkali metals, alkaline earth metal alloys and blends including alkaline earth metals and metal alloys including at least one alkali metal and at least one alkaline earth metal, with water to obtain hydrogen and a residual reaction product including metal hydroxide composed of at least one of alkali hydroxides and alkaline earth hydroxide; and separating hydrogen from the residual reaction product; liquefying the metal reagent by heating to obtain liquid metal reagent under vacuum conditions; injecting the liquid metal reagent into a reactor by metal reagent injecting means and simultaneously injecting, by water injection system, a stoichiometric amount of water with respect to the amount of the liquid metal reagent being injected into the reactor such that a controlled metal reagent/water ratio is maintained in the reactor; transferring hydrogen and the residual reaction product from the reactor to separation means; separating hydrogen from the residual reaction product; transferring separated hydrogen to hydrogen receiving means and transferring the residual reaction product to metal hydroxide receiving means, keeping the metal reagent injecting means water injection system, the reactor, the separating means and the hydrogen receiving means free of oxygen by selectively providing a vacuum in the system.
US08696930B2 Silicon wafer reclamation process
An etchant for removing a porous low-k dielectric layer on a semiconductor substrate includes a hydrofluoric acid-based solvent, a dilating additive for dilating the pores in the porous low-k dielectric, and a passivating additive that forms a passivation layer at the interface between the low-k dielectric layer and the semiconductor substrate.
US08696927B2 Heat transfer system comprising brazed aluminum, method, heat transfer fluid, and additive package
Disclosed herein is heat transfer system, comprising a brazed aluminum component, and a heat transfer fluid in fluid communication with the brazed aluminum component, wherein the heat transfer fluid comprises a liquid coolant, an oxy-anion of molybdenum, tungsten, vanadium, phosphorus, antimony, or a combination thereof, and a corrosion inhibitor. Also disclosed is a method of preventing corrosion in the heat transfer system, and a heat transfer fluid and additive package for use in the heat transfer system.
US08696923B2 Composite of steel and resin and method for manufacturing same
In the composite, an aluminum-plated steel sheet and a resin are securely and integrally joined together. Through chemical etching, the aluminum-plated steel sheet is caused to have a surface configuration, in which three-dimensional protrusions having shapes with a minor diameter of at least 0.3 μm and a major diameter of at least 3 μm are scattered over a plain part and a portion covered with shallow fine recesses with a diameter of 20 to 50 nm in a state of being distributed adjacent to each other on the plain part accounts for 30 to 50% of the surface area of the plain part. The surface of the three-dimensional protrusions is mainly ceramic containing silicon and the plain part is mainly ceramic containing aluminum. The resin is joined through injection molding with the aluminum-plated steel sheet having been inserted into a metallic mold.
US08696919B2 Method for manufacturing a nozzle and an associated funnel in a single plate
A method for manufacturing a nozzle and an associated funnel in a single plate comprises providing the single plate, the plate being etchable; providing an etch resistant mask on the plate, the mask having a pattern, wherein the pattern comprises a first pattern part for etching the nozzle and a second pattern part for etching the funnel; covering one of the first pattern part and the second pattern part using a first cover; etching one of the nozzle and funnel corresponding to the pattern part not covered in step (c); removing the first cover; etching the other one of the nozzle and funnel; and removing the etch resistant mask.
US08696910B2 Chromatography cartridge and method for manufacturing a chromatography cartridge
A chromatography cartridge and method of manufacturing same. A chromatography cartridge of the present invention can include a tubular housing having an open end and an inner surface, and a plug. The plug can be positioned within the open end of the tubular housing and can have an outer circumferential surface, a substantial portion of the outer circumferential surface being fused to the inner surface of the tubular housing. A method for manufacturing a chromatography cartridge can include coupling at least a portion of the outer surface of the plug to at least a portion of the inner surface of the tubular housing in response to rotating at least one of the plug and the tubular housing about the longitudinal axis with respect to the other of the plug and the tubular housing.
US08696908B2 Desalination system and method of wastewater treatment
Various embodiments described herein provide methods and apparatus for releasing treated wastewater into the environment by combining the treated wastewater with a concentrated salty water before discharging the combined water into the environment. The treated wastewater and concentrated salty water may be combined in a ratio that will be less toxic to at least some resident marine life than the treated wastewater alone.
US08696903B2 High-pressure tubing
A method for making conduits includes inserting an inner tube into an outer tube and melting a portion of the inner tube to form a bond with the outer tube. The inner tube includes a polymeric material and the outer tube includes a material having a greater yield strength than the polymeric material. A conduit includes one or more inner tubes at least one of which is melt-bonded to one or more outer tubes. An analytical instrument includes a separation column, a solvent reservoir and pump, a sample injector, a detector to observe an eluent of the separation column, and tubing to transport fluid between components of the instrument.
US08696900B2 Chromatography cartridge and method for manufacturing a chromatography cartridge
A chromatography cartridge and method of manufacturing same. A chromatography cartridge of the present invention can include a tubular housing having an open end and an inner surface, and a plug. The plug can be positioned within the open end of the tubular housing and can have an outer circumferential surface, a substantial portion of the outer circumferential surface being fused to the inner surface of the tubular housing. A method for manufacturing a chromatography cartridge can include coupling at least a portion of the outer surface of the plug to at least a portion of the inner surface of the tubular housing in response to rotating at least one of the plug and the tubular housing about the longitudinal axis with respect to the other of the plug and the tubular housing.
US08696896B2 Apparatus for treating liquid containing impurities
An apparatus for treating a liquid containing impurities may comprise: a filtering chamber for receiving liquid containing impurities, the filtering chamber containing granular media and configured to permit the granular media to interact with the liquid containing impurities, thereby removing impurities from the liquid to produce filtrate; a filtrate section in communication with the filtering chamber for receiving the filtrate, the filtrate section being in communication with a first outlet for outflow of the filtrate; a gas supplying system for delivering gas to the granular media in the filtering chamber for transport of a portion of the granular media to a granular media washer; and a reject section in communication with the granular media washer for receiving a reject mixture comprising liquid and impurities from the granular media washer. The reject section may be in communication with a second outlet for outflow of a portion of the reject mixture.
US08696895B2 Percolation filtering system
A percolation filtering system comprises a flow path of the water to be filtered including a filter cartridge seat (4) for removably receiving a filter cartridge (5) so that said flow path extends through said filter cartridge when said filter cartridge is inserted into said seat, characterized in that it comprises recognition means and counter-means of the suitability of said cartridge, respectively on said cartridge and said seat, suitable for reciprocal interaction when the cartridge is inserted in the seat to enable operation of the filtering system following the cartridge's suitability recognition, or to disable it or signal the suitability/unsuitability respectively of the cartridge if the cartridge is recognized/ not recognized respectively by the recognition means.
US08696892B2 Apparatus for treating radioactive nitrate waste liquid
An apparatus for treating a radioactive nitrate waste liquid includes: a denitrification tank (12) that accommodates active sludge which adsorbs or takes in a radioactive substance in a nitrate waste liquid (11) containing nitrate and the radioactive substance and in which an anaerobic microorganism that reduces the nitrate to nitrogen gas grows; a reaeration tank (14) that aerates and mixes a denitrification-treated liquid (24) treated in the denitrification tank (12) with the active sludge in which the aerobic microorganism grows; and a sludge dissolution tank (81) that dissolves redundant sludge (26A, 26B) discharged from the denitrification tank (12) and the reaeration tank (14). Acetic peracid (80) is supplied to the sludge dissolution tank (81) to dissolve redundant sludge, a sludge lysate is supplied to the denitrification tank (12) as a carbon source (22), and acetic acid is supplied to the denitrification tank (12).
US08696888B2 Hydrocarbon resid processing
The invention concerns integration of hydroprocessing and steam cracking. A feed comprising crude or resid-containing fraction thereof is severely hydrotreated and passed to a steam cracker to obtain an olefins product.
US08696887B2 Catalytic conversion process
A catalytic conversion process which comprises catalytic cracking reaction of a hydrocarbon feedstock contacting with a medium pore size zeolite enriched catalyst in a reactor, characterized in that reaction temperature, weight hourly space velocity and catalyst/feedstock ratio by weight are sufficient to achieve a yield of fluid catalytic cracking gas oil between 12% and 60% by weight of said feedstock, wherein said weight hourly space velocity is between 25 h−1 and 100 h−1, said reaction temperature is between 450° C. and 600° C., and said catalyst/feedstock ratio by weight is between 1 and 30. This invention relates to a catalytic conversion process, especially for heavy feedstock oil to produce higher octane gasoline and an enhanced yield of propylene. More particularly, the invention relates to a process to utilize petroleum oil resources efficiently for decreasing the yield of dry gas and coke significantly.
US08696877B2 Electrode suitable as hydrogen-evolving cathode
The invention relates to a cathode for hydrogen evolution in electrolysis cells, for instance chlor-alkali cells or cells for producing chlorate or hypochlorite, obtained starting from a substrate of nickel or other conductive material galvanically coated with nickel co-deposited with an amorphous molybdenum oxide.
US08696876B2 System and method for generating and using hydrogen gas
A novel electromechanical, chemical, thermal apparatus having the combined properties of a voltage intensifier, a diode and a capacitor for the molecular breakdown of water into its oxygen and hydrogen components. The instant invention uses only water (tap water, distilled water, purified water, etc.) without the need of adding any electrolyte. The system comprises a unique molecular reactor core having conductive inner and outer windings and a molecular reactor control assembly having water level controls via a float switch mechanism and temperature control process serving as the basis for the unique operation of the system. The instant invention provides a novel combination of the molecular reactor core and molecular reactor control assembly, in conjunction with a means for replenishing the water therein, all powered and controlled by simple control circuitry, and having usage implications for various functions, including but not limited to the generation of hydrogen gas.
US08696866B2 Coated paper and a process for making coated paper
The present invention relates to a coated paper product and method for making the coated paper product. The product comprises a paper substrate, which can be of a low quality, that is coated with at least two layers of coating in one embodiment. A first coating layer is applied to the front and back sides of the paper substrate before a second coating layer is applied. The first coating layer comprises titanium dioxide, an aluminum silicate, calcium carbonate, clay and a binder. The second coating layer comprises hollow spherical particles, which provides the coating with an improved ability to spread while improving the coverage and formation of the coating layer, and also comprises a printing additive, titanium dioxide and a binder.
US08696860B1 Lamination of polymer thick film conductor compositions
This invention provides a method for using a polymer thick film conductor composition to form an electrical conductor in an electrical circuit, the method subjecting the deposited thick film conductor composition to lamination. The invention also provides a method for reducing the resistance of an electrical conductor formed from a polymer thick film conductor composition, the method comprising the step of subjecting the electrical conductor to lamination. The invention further provides devices containing electrical conductors made by these methods.
US08696858B2 Apparatus and method for improving center hole radial runout control in optical disk manufacturing
An apparatus and method for controlling radial runout between stacked disk portions (14, 18) and providing a cylindrical pin (20) having at least two diameters (22, 24). The pin is dimensioned and configured to permit the disk portions, which have different center hole dimensions, to be indexed such that a center hole of each disk portion is received by a separate diameter of the pin. The disk portions are maintained in spatial relationship as provided by the pin by spot curing a portion of the adhesive.
US08696857B2 Method for forming a filter mat
A method for forming a filter mat (1) suitable for filter fluids includes forming at least one web section (39) of a mat web (9) and at least one welding line (13, 15, 41) that seals the layers of at least one web section (39) of the mat web (9) to each other. Subsequently, at least one cut (19, 37) is carried out along the at least one welding line (13, 15, 41) such that the at least one web section (39) is cut forming at least one sealed edge region (43).
US08696855B2 Simplified absorbent article construction and method of making
A method includes moving an absorbent composite in a machine direction, severing the composite at a first cut oriented in a direction that is non-parallel and non-perpendicular with the machine direction, severing the composite at a second cut oriented in a direction that is non-parallel and non-perpendicular with the machine direction, severing the composite at a third cut oriented in a direction that is perpendicular to the machine direction, and separating the composite along the first cut, the second cut, and the third cut into discrete absorbent articles.
US08696850B2 Method for making a composite material having at least one twisted thread deposited therein
The invention relates to a method of making a composite material in which at least one reinforcement thread is deposited on a surface according to a path having at least one curved area on the deposition surface, wherein the reinforcement thread is connected to the surface by a polymeric binder, characterized in that a twist is applied to the reinforcement thread before the deposition thereof at least in order to compensate the length differences of the extreme paths of the thread on either side of the width as measured in a direction parallel to the deposition surface: the invention also relates to the composite material thus obtained.
US08696848B2 Inflation and sealing device for inflatable air cushions
The invention is directed to a device for inflating and sealing an inflatable structure, such as inflatable cushions. The device includes an assembly configured for inflating a cushion cavity disposed between first and second layers of a film, and a sealing mechanism that preferably includes a rotary sealing drum, which can include a heat source.
US08696846B2 Method of manufacturing a pneumatic tire
The present invention provides a method of manufacturing a pneumatic tire, which can prevent an air pocket from being generated in a vicinity of a spliced portion of a sheet member (B) to be attached to an inner liner, even in the case of using, as the inner liner, a sheet member (A) made of a composition containing a resin component. The method includes a step of laminating a sheet member (A) and a sheet member (B) while being pressed on a making drum. The sheet member (B) is made of a rubber composition, and has two end portions in the circumferential direction overlapped and spliced with each other. In the method, a cut line of each end of the sheet member (B) in the circumferential direction has a vertex in the intermediate point in the width direction of the sheet member (B). Moreover, the cut line is displaced in the opposite direction to the rotational direction of the making drum as extending from the vertex to each of the right and left edges in the width direction.
US08696841B2 Bonding material with increased reliability and method of manufacturing ceramic bonded body
A bonding material and a related manufacturing method are disclosed in which an unfired ceramic body A, internally formed with a cavity portion or a surface formed with a concaved portion, and an unfired ceramic body B are bonded to each other. The bonding material is applied to a bonding area between the unfired ceramic bodies A and B in a thickness ranging from 10 to 25 μm to provide a bonded body that is fired to obtain a ceramic bonded body. The bonding material contains an inorganic powder, an organic binder and an organic solvent in a composition to satisfy relationships 0≦X—Z≦2.6 and 0≦Y—Z≦2.6 where “X” represents a firing contraction ratio (%) of the unfired ceramic body A, “Y” a firing contraction ratio (%) of the unfired ceramic body B, and “Z” a firing contraction ratio of tie bonding material.
US08696838B1 Foamed celluloid process using expandable beads
A method of manufacture of foamed celluloid molded products, involving three steps for the manufacture of higher density (0.7 to 1.25 gm/cc) foamed celluloid products or simple geometry lower density (0.2 to 0.7 gm/cc) foamed celluloid products, and four steps for the manufacture of lower density foamed celluloid products of any geometry. The three step process involving: (1) providing small, uniform, pieces of celluloid; (2) presoaking the pieces in a physical blowing agent (PBA) under pressure; and (3) foaming at raised temperature a controlled quantity of the presoaked pieces in a mold—to obtain the desired shape and density. For a lower density foamed celluloid product, of any moldable geometry, the steps are to: (1) small pieces of celluloid, that (2) have been presoaked in a PBA, are (3) pre-expanded to an intermediate density, and then (4) foam the desired lower density foamed product in a mold at raised temperature.
US08696837B2 Heavy ANFO and a tailored expanded polymeric density control agent
The present invention is directed to an explosive composition comprised of heavy ANFO and expanded polymeric beads that have a density that is less than the density of the heavy ANFO. The expanded polymeric beads have a size that is determined or based on the size of ammonium nitrate prills used in the heavy ANFO portion of the composition. In one embodiment, the expanded polymeric beads that are utilized in the composition are at least 70% of the lower limit of the mesh size of the predominant ammonium nitrate prill mesh size. In another embodiment, the expanded polymeric beads are at least 70% of the a size that is related to the average mesh size of the ammonium nitrate prills.
US08696835B2 Austenitic stainless steel for hydrogen gas and a method for its manufacture
An austenitic stainless steel for use in a hydrogen gas atmosphere comprises, in mass %, C: 0.10% or less, Si: 1.0% or less, Mn: 0.01 to 30%, P: 0.040% or less, S: 0.01% or less, Cr: 15 to 30%, Ni: 5.0 to 30%, Al: 0.10% or less, N: 0.001 to 0.30% with the balance Fe and inevitable impurities. An X-ray (111) integration intensity of a cross section along the direction rectangular to the working direction is five times that in a random direction or less, and the X-ray integration intensity ratio of a cross section along the working direction satisfies I(220)/I(111)≦10. The high strength steel can also contain one or more of the groups of Mo and W; V, Nb, Ta, Ti, Zr and Hf; B; Cu and Co; Mg, Ca, La, Ce, Y, Sm, Pr and Nd.
US08696831B2 Chromate-free conversion film solution and the method of applying the solution to magnesium alloys
Disclosed herein is a chromate-free conversion film solution and a method of applying the solution to magnesium and magnesium alloys. The solution contains zirconium ions, manganese ions, barium ions and phosphate corrosion inhibitor; and the pH of the said solution is in the range of 1-5; and may further comprise molybdate as accelerant. The method comprises degreasing, acid etching, surface activation, surface adjusting, and film forming steps. The conversion film obtained in accordance with the disclosed method is uniform, smooth, and compact and has high corrosion resistance and good adhesion with paint film. Moreover, the chromate-free conversion film solution is environmentally friendly and possesses fast film growth rates.
US08696824B2 Dishwasher, a door assembly for the dishwasher, and an associated method for drying dishware
A dishwasher, a door assembly for the dishwasher and a method of drying the dishware in the dishwasher are provided. The dishwasher may include a sensor configured to measure the turbidity of the water in the dishwasher which is used to determine a wash load size. A control unit of the dishwasher may determine and control cycle times, temperatures, heating elements and a blower of the dishwasher based on the wash load size. The dishwasher may include a humidity level determination that may also be used by the control unit to control the operations of the dishwasher. The door assembly may include a duct configured to receive moisture-laden air creating during the drying cycle and encourage the condensation of the water from the air such that the water may be redirected back to the tub portion of the dishwasher and the dry air may be directed out of the dishwasher.
US08696819B2 Methods for cleaning tubulars using solid carbon dioxide
Systems and methods for cleaning the interior surfaces of tubular members are provided. A flexible conduit having a nozzle disposed on an end can be disposed within the bore of a tubular to be cleaned. The nozzle can have an internal 5-15 degree tapered section with a length-to-diameter ratio of greater than about 2:1. The nozzle can have an outer diameter that is about 80% to 99% of the inner diameter of the tubular. A fluid suspension containing air and solid carbon dioxide can be passed through the nozzle, impinging the surrounding inner surface of the surrounding tubular as the nozzle is disposed within the tubular. The solid carbon dioxide and compressed air suspension can have a solids concentration of from about 0.1% to 10.0% solids. The solids delivery rate through the nozzle can range from about 0.5 lbs/minute to about 5 pounds/minute. The flow of the suspension through the nozzle can be controlled using a remote device.
US08696817B2 Equipment and method for removing deposits created in electrolytic refining
The invention relates to an equipment for removing deposits accumulated in electrolytic refining on the surface of an electrode, such as a cathode, said equipment including at least one element for stripping the deposits and at least one element for controlling the stripping element; said equipment includes at least one stripping element that is turnably movable in the vertical direction of the cathode, and the cathode can be bent owing to the contact with said stripping element. The invention also relates to a method realized by said equipment.
US08696814B2 Film deposition apparatus and film deposition method
A disclosed film deposition apparatus includes a process chamber inside which a reduced pressure space is maintained; a gas supplying portion that supplies a film deposition gas to the process chamber; a substrate holding portion that is made of a material including carbon as a primary constituent and holds a substrate in the process chamber; a coil that is arranged outside the process chamber and inductively heats the substrate holding portion; and a thermal insulation member that covers the substrate holding portion and is arranged to be separated from the process chamber, wherein the reduced pressure space is separated into a film deposition gas supplying space to which the film deposition gas is supplied and a thermal insulation space defined between the substrate holding portion and the process chamber, and wherein a cooling medium is supplied to the thermal insulation space.
US08696813B2 Method of manufacturing silicon single crystal, apparatus for pulling silicon single crystal and vitreous silica crucible
Leakage of silicon melt is monitored and touch of a seed crystal at the silicon melt is detected, and in addition, reinforcement of a vitreous silica crucible to be endurable during pulling for a long time and decrease of impurity concentration of a silicon single crystal can be expected. A method for manufacturing a silicon single crystal is provided. The method includes: detecting touching status of a seed crystal at silicon melt by supplying voltage V1 using a crucible side as a negative electrode and a wire side as a positive electrode and by monitoring change of the voltage, when the seed crystal provided at a front end of the wire touches the silicon melt inside a vitreous silica crucible; devitrifying an inner surface of the vitreous silica crucible as supplying voltage V2 using the crucible side as a positive electrode and the wire side as a negative electrode during a temperature control period; and growing a silicon single crystal by slowly pulling the seed crystal as supplying voltage V3 using the crucible side as a negative electrode and the wire side as a positive electrode after the temperature control period.
US08696804B2 Carbon dioxide absorbent fluid for a carbon dioxide sequestering system on a vehicle
A carbon dioxide storage means stores the carbon dioxide released in a heat exchanger. The heat exchanger cools the exhaust gas emitted by the internal combustion engine, and includes a thermal electric generator (TEG) configured to couple thermally the exhaust gas chamber to the absorber fluid chamber in a manner effective to heat the CO2 absorbent fluid by heat from the engine exhaust to release CO2 gas from the CO2 absorbent fluid and generate electricity in response to a temperature difference therebetween. The CO2 absorbent fluid is one of: a) an aliphatic di-functional nitrile (e.g. pimelonitrile); and b) an oligomeric poly-acrylonitrile (PAN).
US08696803B1 Air permeable scenting latex formulation for spray application on an air filter
An aqueous scenting formulation formulated for spray application on an air scenting device for use in an HVAC system to form an air permeable barrier film which slows the rate of water evaporation and provides long lasting freshening or scenting of air flowing through the device with minimal blockage of air flow through the HVAC system having a latex in the amount of from 10 percent to 50 percent by weight of the aqueous scenting formulation, wherein the latex consists of a vinyl/polyvinyl acetate, and wherein the mean particle size of the vinyl/polyvinyl acetate in the latex is from 75 microns to 90 microns in diameter; a surfactant selected from the group consisting of: non-ionic and anionic surfactants and mixtures thereof; and a fragrance material.
US08696800B2 Systems and methods for cleaning air
An HVAC system has an electrically powered air cleaner, a fan configured to selectively move air through the air cleaner, and a controller having an interface for receiving a selection of a clean air cycle. The controller is configured to control a clean air delivery rate (CADR) of the HVAC system for a clean air cycle duration in response to a receipt of a selection of the clean air cycle. A method of controlling air cleaning includes displaying a first clean air cycle that is configured to control a clean air delivery rate for a first clean air cycle duration wherein the first clean air cycle is associated with a first air flow related setting and a first air cleaner power level setting, selecting the first clean air cycle, and overriding at least one of a previous air flow related setting and a previous air cleaner power level setting.
US08696785B2 Method and apparatus for recycling battery pack
A method for recycling a battery pack includes steps of: roasting the battery pack that houses a battery assembly that is in a charged condition, as it is, dismantling the roasted battery pack and separating the battery pack into unit cells and parts other than the unit cells, comminuting the unit cells obtained by separation, washing and screening the comminuted cells, dehydrating a slurry below a sieve after screening and recovering metals used for positive and negative electrodes, and recovering metal containing nickel by magnetically separating metal remaining on the sieve after screening, using a magnet.
US08696777B1 Marine engine exhaust systems having an oxygen sensor
A marine engine exhaust system has an exhaust conduit conveying engine exhaust gas from upstream to downstream, a sensor sensing oxygen content of the exhaust gas in the conduit, and a shield located in the conduit. The shield is configured to shield the sensor from deleterious effects of liquid when liquid and exhaust gas is reverted in the exhaust conduit from downstream to upstream.
US08696776B2 Abnormality determination apparatus for particulate filter
An abnormality determination apparatus includes a particulate filter provided in the exhaust passage of an internal combustion engine that collects particulate matter in the exhaust gas discharged from the internal combustion engine, a particulate matter deposition amount detection device provided downstream of the particulate filter, and a abnormality determination portion. The particulate matter deposition amount detection device includes a detecting element that detects the particular matter that flows toward the particulate matter deposition amount detection device and that is not trapped by the particulate filter, and then outputs a value corresponding to a deposition amount deposited the particulate matter on the detecting element. The abnormality determination portion determines, whether an abnormality is present in the particulate filter based on the gradient of an output waveform of the particulate matter deposition amount detection device.
US08696775B2 Conversion of C—O—H compounds into hydrogen for power or heat generation
Methods are disclosed for generating electrical power from a compound comprising carbon, oxygen, and hydrogen. Water is combined with the compound to produce a wet form of the compound. The wet form of the compound is transferred into a reaction processing chamber. The wet form of the compound is heated within the reaction chamber such that elements of the compound dissociate and react, with one reaction product comprising hydrogen gas. The hydrogen gas is processed to generate electrical power.
US08696771B2 Compact integrated combustion reactors, systems and methods of conducting integrated combustion reactions
A compact integrated combustion reactor is described. In a preferred embodiment, the combustion catalyst is disposed in a staggered configuration such that the hot spot in an adjacent endothermic reaction chamber is substantially less than would occur with a conventional, unstaggered configuration. The integrated reactor may also include a methanation chamber for methanation of a reformate product. Systems containing reactant and product streams, and methods of conducting integrated combustion reactions are also described. A staggered catalyst conformation can be used more broadly for thermal chemical reactions requiring heat transfer in a layered device.
US08696770B2 Apparatus and method for recycling coal ash
The present invention relates to an apparatus and method for recycling coal ash comprising an unburned coal ash recovery unit and a lightweight aggregate manufacturing unit and is provided in an existing thermoelectric power plant and in which coal ash generated in the thermoelectric power plant is completely recycled for specific purposes using the coal ash recycling apparatus. According to the invention, the surrounding environment can be prevented from being contaminated during the transportation of waste to a recycling factory and transportation expenses can be reduced. Moreover, coal ash is completely recycled for specific uses, such that unburned carbon contained in the coal ash can be used. Also, coal ash can be recycled even as concrete admixtures having strict standards. In addition, the present invention can prevent environmental contamination caused by the landfilling of waste and recycle waste, thereby reducing the loss of land and the waste of resources.
US08696764B2 Further improvements to ankle-foot prosthesis and orthosis capable of automatic adaptation to sloped walking surfaces
The present invention relates to an improved system for use in rehabilitation and/or physical therapy for the treatment of injury or disease to the lower limbs or extremities. The system can enable an amputee to proceed over any inclined or declined surface without overbalancing. The system is mechanically passive in that it does not utilize motors, force generating devices, batteries, or powered sources that may add undesirable weight or mass and that may require recharging. In particular the system is self-adapting to adjust the torque moment depending upon the motion, the extent of inclination, and the surface topography. An additional advantage of the improvement is that the system can be light and may also be simple to manufacture.
US08696756B2 Muscular-skeletal force, pressure, and load measurement system and method
A measurement system for measuring a parameter of the muscular-skeletal system is disclosed. The measurement system comprises a capacitor, a signal generator, a digital counter, counter register, a digital clock, a digital timer, and a data register. The sensor of the measurement system is the capacitor. The measurement system generates a repeating signal having a measurement cycle that corresponds to the capacitance of the capacitor. The capacitor comprises more than one capacitor mechanically in series. Electrically, the capacitor comprises more than one capacitor in parallel. In one embodiment, the capacitor includes a dielectric layer comprising polyimide. A force, pressure, or load is applied to the capacitor that elastically compresses the device.
US08696748B2 Sheaths for implantable fixation devices
Sheaths for implantable fixation devices are disclosed. Sheaths have a flexible body with a perforated wall, an open end, a closed end, and a body interior sized and shaped to receive the fixation device.
US08696746B2 Ophthalmic lens with optical sectors
The invention relates to an ophthalmic lens comprising a main lens part, a recessed part, an optical center, and an optical axis through said optical center, said main lens part having at least one boundary with said recessed part, said main lens part having an optical power of between about −20 to about +35 dioptre, said recessed part positioned at a distance of less than 2 mm from said optical center and comprising a near part having a relative dioptre of about +1.0 to about +5.0 with respect to the optical power of said main lens part, said boundary or boundaries of said recessed lens part with said main lens part form a blending part or blending parts, are shaped to refract light away from said optical axis, and have a curvature resulting in a loss of light, within a circle with a diameter of 4 mm around said optical center, of less than about 15%.
US08696745B2 Heart help device, system, and method
The present invention relates to an implantable device for improving the pump function of the heart of a human patient by applying an external force on the heart muscle, said device comprising at least one pump device comprising: a first part having a first surface, and a second part having a second surface. The first part is displaceable in relation to the second part and said first and second surfaces abut each other, at least partially. The second part exerts, directly or indirectly, force on an external part of said heart muscle.
US08696739B2 Barbed anchor
An endoluminal prosthesis includes a support structure including a curvilinear portion having a first strut and a second strut that meet at an apex. Disposed on the support structure is an anchor with an anchor body and one or more barbs extending outwardly from the anchor body. The anchor body can fit at least partially about, and can conform to the first strut, second strut, and the apex. A curved portion of the anchor and the curvilinear portion of the support structure can be co-formed, resulting in a secure interference fit so that welding, soldering, or other joining mechanisms can be avoided. Cutouts can be formed along the curved portion of the anchor to relieve stress or strain during the co-forming process.
US08696735B2 Stents for blood vessels
A stent for supporting part of a blood vessel includes a supporting portion around which or within which a part of an intact blood vessel other than a graft can be placed. The stent internally or externally supports that part of the blood vessel. The supporting portion of the stent is of a shape and/or orientation whereby flow within the vessel is caused to follow a non-planar curve. By maintaining a non-planar curvature in the vessel itself, favorable blood flow velocity patterns can be achieved through the generation therein of “swirl” flow. Failures in such vessels through diseases, such as thrombosis, atherosclerosis, intimal hyperplasia or through blockage, kinking or collaps, can be significantly reduced.
US08696732B2 Stent delivery system
A drainage stent delivery system including an elongate shaft of a medial device, a drainage catheter or stent, and a retention mechanism for selectively retaining the drainage stent on the elongate shaft. The tubular stent is positioned on and surrounding the elongate shaft. The elongate shaft includes a distal tip portion which is deflectable from a first position to a second position, the distal tip portion of the elongate shaft being biased toward the first position. Deflecting the distal tip portion of the elongate shaft from the first position to the second position moves the distal tip portion toward the central longitudinal axis of the tubular stent to allow the stent to be decoupled from the elongate shaft.
US08696722B2 Optogenetic magnetic resonance imaging
Disclosed herein are systems and methods involving the use of magnetic resonance imaging and optogenetic neural stimulation. Aspects of the disclosure include modifying a target neural cell population in a first region of a brain to express light-responsive molecules. Using a light pulse, the light-responsive molecules in the target neural cell population are stimulated. Multiple regions of the brain are scanned via magnetic resonance imaging. The scans allow for observation of a neural reaction in response to the stimulation in at least one of the multiple regions of the brain.
US08696721B2 Orthopedic expansion fastener
Devices are disclosed for treating the vertebral column. A fastener having a fastener head comprising a screw lumen and fastener shaft is provided. In some embodiments, an external groove and one or more openings between the screw lumen and an external groove are provided. An expandable member is located at least partially in the external groove and protrudes through the one or more openings into the screw lumen. Alternative fixation systems and screw retaining assemblies are also contemplated.
US08696719B2 Methods and devices for treating hallux valgus
The various embodiments disclosed herein relate to implantable devices for the treatment of structural bone and joint deformity, including hallux valgus. More specifically, the various embodiments include systems, devices, and methods for implantation of an implantable device having at least one bone anchor with deployable prongs for treating such deformity.
US08696717B2 Multi-planar, taper lock screw with additional lock
A pedicle screw construct includes a pedicle screw, a coupling, a collet, and a set screw. The pedicle screw includes a shank having a helical thread formed thereon and a head at one end. The collet is positioned atop the head of the pedicle screw. The collet and pedicle screw are inserted into the coupling. The set screw is positioned in the collet such that the set screw contacts a portion of the rod and is releasably secured to the pedicle screw via a gripping tool. The pedicle screw is rotatable and pivotable relative to the collet and coupling assembly.
US08696711B2 Polyaxial bone anchor assembly with one-piece closure, pressure insert and plastic elongate member
A medical implant assembly includes a polyaxial bone anchor having a shank, a receiver, a lower compression insert with planar surfaces for closely receiving an elongate connecting member with planar surfaces and a one-piece closure structure. The connecting member is made from a polymer. The closure structure engages both the connecting member and the insert with the engagement between the closure structure and the insert securely locking the polyaxial mechanism even if the connecting member exhibits creep.
US08696710B2 Device and accessories for limiting flexion
A device may be used to limit flexion of the spine without substantially limiting extension of the spine. Various accessories, instruments, and methods may be used to help deploy the flexion limiting device, manipulate, and adjust it.
US08696708B2 Facet interference screw
A facet interference screw (10) for insertion between the facet joints of adjacent superior and inferior vertebrae includes an externally threaded shaft portion and a head. The facet interference screw is preferably split into first (20) and second (30) components, each including an outer, semicircular externally threaded surface (22, 32) so that when coupled together the semicircular externally threaded surfaces form the externally threaded shaft portion. The inner surfaces (24, 34) of the first and second components may include curved contacting surfaces so that when inserted, the first component is movable with respect to the second component. Alternatively, the screw may include a damping component (60a′) between the inner surfaces of the first and second components to facilitate damping of the first and second components with respect to one another. The damping component preferably also facilitates articulated motion of the first and second components.
US08696707B2 Facet joint stabilization
Various implementations for therapy to facet joints connecting vertebrae are disclosed including: A) Facet joint stabilization that may be implemented using stabilization band that maintains tension between two anchors. The stabilization band may be retained in any one of a number of ways including the use of an anti-slip device such as a mechanically deformed crimp that abuts one of the anchors. B) Facet joint augmentation may be implemented by dilating the facet joint and inserting a facet joint spacer before adding a facet joint stabilization assembly. The facet joint augmentation may include connecting a tail section of the facet joint spacer to the first anchor used in the facet joint stabilization assembly. C) Facet joint immobilization may be implemented by inserting a fastener across the facet joint and into the vertebra so that the assembled fastener expands inside the vertebra.
US08696704B2 Methods and devices for repairing tissue
Suture anchor systems for repairing torn or damaged tissue are described herein. In one embodiment, a system can include a first suture loop having a first suture anchor coupled thereto, the first suture loop including a slip knot formed thereon to allow a size of the first suture loop to be adjusted. The system can also include a second suture loop coupled to the first suture loop and having a second suture anchor coupled thereto. The second suture loop can have a fixed size. In use, the suture anchors can be deployed through tissue to be repaired and into the anchoring tissue at a position spaced apart from one another by a selected distance. The length of the first suture loop can then be tensioned to re-approximate the torn or damaged tissue toward the anchoring tissue, thereby securely attached the torn tissue to the anchoring tissue.
US08696696B2 Device and kit for treatment of disorders in the heart rhythm regulation system
A tissue cutting device is disclosed, which is structured and arranged to be inserted through the vascular system into a body vessel adjacent to the heart and/or into the heart, and to be subsequently subjected to a change of shape in order to penetrate into the heart tissue. The tissue cutting device may thus be used for treating disorders to the heart rhythm regulation system. A kit of devices provides a plurality of devices for creating a lesion pattern for treating such disorders.
US08696695B2 Guidewire positioning catheter
Described herein are guidewire positioning and support devices, method for using them, method of treating a subject using them, and systems including such guidewire positioning and support devices. These devices typically include a rotatable distal tip region that may include one or more wedges. The wedges may be extendable from the rotatable distal tip. The distal end of the device may be steerable, and may be steered while still rotating the distal end of the device. The wedges (which may include sharp forward-cutting blades and blunt lateral portions) can be extended from the distal housing and locked in any position (extended, partially extended or retracted) and rotated clockwise and/or counterclockwise while locked in a retracted, extended or partially extended position. The distal region of the device may also be controllable steered from the proximal end of the device. Systems including these guidewire support catheters are also described, as are method of using them, including methods of treating chronic total occlusions.
US08696693B2 Delivery system, method, and anchor for medical implant placement
An anchor for a medical implant, methods of manufacturing the anchor, and procedures for placing a medical implant, such as for diagnosing, monitoring and/or treating cardiovascular diseases. The anchor has a base portion with first and second longitudinal ends and a cage therebetween. The anchor further has flexible arms, flexible legs, features for securing the medical implant within the cage of the base portion, and a coupler portion connected to and spaced apart from the second longitudinal end of the base portion. The anchor is adapted to have a deployed configuration in which the arms and legs radially project away from the base portion, the arms axially project toward the second longitudinal end of the base portion, and the legs axially project toward the first longitudinal end of the base portion. Convex surfaces of the arms and legs are adapted to clamp the anchor to a wall.
US08696684B2 Animal tag applicator
Described are an animal tag applicator, a device for advancing a strip of animal tags, a leg bending die for bending the legs of animal tags, and methods for applying an animal tag to a body part of an animal.
US08696678B2 Medical treatment material delivery apparatus
A delivery apparatus for delivering material to a medical treatment site which comprises a plurality of containers for containing the material, a dispensing outlet and means for bringing each container into communication with the outlet and means for transferring material from the containers and through the outlet. The plurality of containers may be removably mounted within a removable cartridge. The apparatus is arranged so that the cartridge is biased to sequentially move each of the containers into communication with the outlet. The outlet may be provided at the end of a dispensing nozzle where the dispensing nozzle has an inner cross-sectional area that is uniform and the same as the containers so that no taper is provided as the material is dispensed from the containers and out of the outlet.
US08696675B2 Proximity-triggered computer-assisted surgery system and method
A computer-assisted surgery system comprises a first surgical device with a tracking unit tracked during a surgical procedure and adapted to perform a first function associated to the surgical procedure. A second surgical device is adapted to perform a second function associated to the surgical procedure. A triggered unit is triggered when the first surgical device and the second surgical device reach a predetermined proximity relation. A surgical procedure processing unit tracks the first surgical device. A trigger detector detects a triggering of the triggered unit. A CAS application operates steps of a surgical procedure. A controller commands the CAS application to activate a selected step associated with the second function in the surgical procedure when the trigger detector signals a detection. An interface displays information about the selected step in the surgical procedure.
US08696674B2 Tissue harvesting
The present disclosure relates to a tissue collection apparatus including a housing defining an inlet and an outlet and a tissue scaffold suitable for disposal within the housing, the tissue scaffold configured to be loaded with the tissue under the application of an aspiration force applied through the tissue collection apparatus.
US08696671B2 Percutaneous tissue excision devices
A device for percutaneously excising tissue. In an embodiments the device comprises an outer tubular. In addition, the device comprises an inner tubular slidingly received within the outer tubular, wherein the inner tubular has a distal end including an upper member and a lower member. Further, the device includes an open position with the distal end fully extended from the outer tubular, and a closed position with the distal end disposed within the outer tubular, wherein the upper member is biased away from the lower member and is disposed at an open angle θO relative to the lower member when the device is in the opened position.
US08696669B2 Fixation device for the fixation of bone fragments
A fixation device for the fixation of bone fragments, applicable to the mutual fastening of bone fragments temporarily separated during a surgical operation or as a result of a trauma. The device is also suitable for the fixation of a bone flap in the replacement thereof in a corresponding aperture made in the cranium or cranial bone mass. The device is made of biocompatible material and comprises a flexible strip and fastening means, the strip having a length allowing the formation of a fastening loop tightly fastening the bone fragments to be joined together. The fastening means are provided with at least one opening provided with interlocking means allowing the passage of a free end of the strip and preventing its extraction in the direction opposite to the insertion.
US08696668B2 Adjustable bone stabilizing frame system
By providing components securable to anchor pins or screws of different diameters as well as providing clamps which hold associated pins in any position during adjustments, an external fixation or adjustable frame structure is provided which is capable of being quickly and easily assembled in any desired configuration. In the present invention, the frame structure is retained in any assembled configuration in order to allow final adjustments to be made, prior to the final securement of the frame assembly in the precisely desired configuration by closure of each clamp member. In this way, an entire frame assembly is capable of being constructed, adjusted, and readjusted in order to assure each component is oriented in the precisely desired position prior to final closure of the clamping members. In one preferred embodiment, the clamping members employed in the frame structure of the present invention incorporate friction pins internally mounted in each clamp which engages the rod member once this rod is inserted into the jaws of the clamp. In this way, any rod member inserted into the clamping jaws contacts the surface of the jaws and the friction pin, preventing the rod member from sliding or moving relative to the clamp. In addition, by incorporating a uniquely constructed, moving wedge plate that is adjustably engageable with any cooperating anchor pin, secure affixation of the mounting member with the anchor pins of any diameter is easily achieved, regardless of the orientation configuration, or diameter of the anchor pin.
US08696665B2 Surgical cutting and sealing instrument with reduced firing force
A surgical instrument is provided that can comprise and end effector including two jaws and a cutting member configured to move between the jaws. In at least one embodiment, one or both of the jaws may be flexible, such that a jaw is configured to flex when gripping tissue. Further, at least one of the jaws may include a thin cross-sectional area such that the jaw flexes when gripping tissue. Additionally, in at least one embodiment, one or more compression elements may extend from the cutting member and may be configured to cause the jaws to close when the cutting member is advanced. The compression elements may comprise a roller and/or a low-friction material. Moreover, in at least one embodiment, one or both of the jaws may be precurved, away from the cutting member's longitudinal axis. Accordingly, in various embodiments, the overall force required to advance the cutting member and/or close the jaws may be reduced.