最新美国发明专利第2014-02-18期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US08653533B2	Semiconductor device and method of manufacturing the same A method of manufacturing a semiconductor device includes the steps of forming a silicon oxide film on a silicon carbide substrate, annealing the silicon carbide substrate and the silicon oxide film in gas containing hydrogen, and forming an aluminum oxynitride film on the silicon oxide film after the annealing of the silicon carbide substrate and the silicon oxide film.
US08653532B2	Display device and method for manufacturing display device Disclosed herein is a display device, including: a substrate; a circuit part configured to include a drive element; a planarization insulating layer; an electrically-conductive layer including a plurality of first electrodes and an auxiliary interconnect; an aperture-defining insulating layer configured to insulate the plurality of first electrodes from each other and have an aperture through which part of the first electrode is exposed; a plurality of light emitting elements; and a separator configured to be formed by removing the planarization insulating layer at a position between a display area, in which the plurality of light emitting elements connected to the drive element are disposed, and a peripheral area which is surrounding the display area. A method of manufacturing a display device is also provided.
US08653530B2	Thin film transistor array panel The present invention relates to a thin film transistor array panel and a manufacturing method thereof that prevent disconnection of wiring due to misalignment of a mask, and simplify a process and reduce cost by reducing the number of masks. The thin film transistor array panel according to the disclosure includes a source electrode enclosing an outer part of the first contact hole and formed on the second insulating layer; a drain electrode enclosing an outer part of the second contact hole and formed on the second insulating layer; a first connection electrode connecting the source region of the semiconductor layer and the source electrode through the first contact hole; and a second connection electrode connecting the drain region of the semiconductor layer and the drain electrode through the second contact hole.
US08653529B2	Semiconductor device and method of manufacturing the same In a semiconductor device in which a glass substrate is attached to a surface of a semiconductor die with an adhesive layer being interposed therebetween, it is an object to fill a recess portion of an insulation film formed on a photodiode with the adhesive layer without bubbles therein. In a semiconductor die in which an optical semiconductor integrated circuit including a photodiode having a recess portion of an interlayer insulation film in the upper portion, an NPN bipolar transistor, and so on are formed, generally, a light shield film covers a portion except the recess portion region on the photodiode and except a dicing region. In the invention, an opening slit is further formed in the light shield film, extending from the recess portion to the outside of the recess portion, so as to attain the object.
US08653524B2	Touch-sensing display device and method for manufacturing the same A touch panel display and method for manufacturing the same are disclosed. The touch panel display includes a first substrate, a second substrate, a touch-sensing member, and a liquid crystal layer. The first substrate has a first surface and a second surface thereon. The second substrate has an element array and is disposed on the second surface of the first substrate. The touch-sensing member locates on the first surface of the first substrate. Furthermore, the touch-sensing member includes a conductive layer, a patterned electrode layer, and a protective layer. The patterned electrode layer is correspondingly located on the periphery of the first substrate. The protective layer covers the conductive layer, and the patterned electrode layer. The conductive layer locates between the protective layer and the first substrate. In addition, the liquid crystal layer is disposed between the first and the second substrate.
US08653515B2	Thin film transistor and thin film transistor array panel Provided is a thin film transistor and thin film transistor panel array. The thin film transistor includes: a substrate; a gate electrode disposed on the substrate; a semiconductor layer disposed on the substrate and partially overlapping with the gate electrode; a source electrode and a drain electrode spaced apart from each other with respect to a channel region of the semiconductor layer; an insulating layer disposed between the gate electrode and the semiconductor layer; and a barrier layer disposed between the semiconductor layer and the source electrode and between the semiconductor layer and the drain electrode, in which the barrier layer comprises graphene. An ohmic contact is provided based on the type of material used for the semiconductor layer.
US08653513B2	Semiconductor device with sidewall insulating layer A semiconductor device includes an oxide semiconductor layer, a source electrode and a drain electrode in contact with the oxide semiconductor layer, a gate electrode overlapping with the oxide semiconductor layer, and a gate insulating layer between the oxide semiconductor layer and the gate electrode, in which the source electrode or the drain electrode comprises a first conductive layer and a second conductive layer having a region which extends beyond an end portion of the first conductive layer in a channel length direction and which overlaps with part of the gate electrode, in which a sidewall insulating layer is provided over the extended region of the second conductive layer, and in which the sidewall insulating layer comprises a stack of a plurality of different material layers.
US08653511B2	Organic light emitting diode display An organic light emitting diode (OLED) display may be constructed with a substrate; a first electrode formed on the substrate; a barrier rib formed on the substrate and having an opening exposing the first electrode; an organic emission layer formed on the first electrode; and a second electrode formed on the organic emission layer. The barrier rib includes an isolating groove formed between organic emission layers of neighboring pixels. Accordingly, in the organic light emitting diode (OLED) display, the isolating groove is formed at the barrier rib such that ink is prevented from crossing over the barrier rib and flowing into a neighboring pixel without a hydrophobic surface treatment of the barrier rib.
US08653510B2	Enhanced E-field sensing using negative capacitance FET subthreshold slope enhancement In certain embodiments, a field effect transistor (FET) can include a substrate, a source electrode, a drain electrode, a ferroelectric material layer, a first gate electrode, and a second gate electrode to maintain an optimal polarization state of the ferroelectric material layer. In other embodiments, a FET can include a film, first and second gates on the film, a ferroelectric material layer covering the film and gates, an insulating layer substantially covering the ferroelectric material layer, a source and a drain on the insulating layer, and a pentacene layer.
US08653505B2	Organic thin film transistor and process for manufacturing same An organic thin film transistor includes a dielectric layer and an active layer overlapping the dielectric layer, a source contact and a drain contact arranged on a surface of the active layer opposite the dielectric layer and mutually separated by an intermediate region, the source contact and drain contact having first and second inner walls, respectively, facing the intermediate region, and a gate contact arranged on a portion of another surface of the dielectric layer opposite the active layer and having first and second side walls aligned with the first and second inner walls, respectively.
US08653503B2	Optoelectronic device based on non-polar and semi-polar aluminum indium nitride and aluminum indium gallium nitride alloys A high-power and high-efficiency light emitting device with emission wavelength (λpeak) ranging from 280 nm to 360 nm is fabricated. The new device structure uses non-polar or semi-polar AlInN and AlInGaN alloys grown on a non-polar or semi-polar bulk GaN substrate.
US08653502B2	Group III nitride semiconductor light-emitting device The present invention provides a Group III nitride semiconductor light-emitting device exhibiting high-intensity light output in a specific direction and improved light extraction performance. The Group III nitride semiconductor light-emitting device comprises a sapphire substrate, and a layered structure having a light-emitting layer provided on the sapphire substrate and formed of a Group III nitride semiconductor. On the surface on the layered structure side of the sapphire substrate, a two-dimensional periodic structure of mesas is formed with a period which generates a light intensity interference pattern for the light emitted from the light-emitting layer. The light reflected by or transmitted through the two-dimensional periodic structure has an interference pattern. Therefore, the light focused on a region where the light intensity is high in the interference pattern can be effectively output to the outside, resulting in the improvement of light extraction performance as well as the achievement of desired directional characteristics.
US08653501B2	Emitting device and manufacturing method therefor Provided is an emitting device which is capable of improving the luminous efficiency of an emitting layer formed using a group IV semiconductor material and obtaining an emission spectrum having a narrow band, and a manufacturing method therefor. The emitting device comprises: an emitting layer having a potential confinement structure, comprising: a well region comprising a group IV semiconductor material; and a barrier region being adjacent to the well region and comprising a group IV semiconductor material which is different from the group IV semiconductor material in the well region, wherein: a continuous region from the well region over an interface between the well region and the barrier region to a part of the barrier region comprises fine crystals; and a region in the barrier region, which is other than the continuous region comprising the fine crystals, is amorphous or polycrystalline region.
US08653500B1	Volume-scalable high-brightness three-dimensional visible light source A volume-scalable, high-brightness, electrically driven visible light source comprises a three-dimensional photonic crystal (3DPC) comprising one or more direct bandgap semiconductors. The improved light emission performance of the invention is achieved based on the enhancement of radiative emission of light emitters placed inside a 3DPC due to the strong modification of the photonic density-of-states engendered by the 3DPC.
US08653496B2	Memory cells Some embodiments include a memory cell that contains programmable material sandwiched between first and second electrodes. The memory cell can further include a heating element which is directly against one of the electrodes and directly against the programmable material. The heating element can have a thickness in a range of from about 2 nanometers to about 30 nanometers, and can be more electrically resistive than the electrodes. Some embodiments include methods of forming memory cells that include heating elements directly between electrodes and programmable materials.
US08653492B1	Target for laser produced plasma extreme ultraviolet light source Techniques for generating EUV light include directing a first pulse of radiation toward a target material droplet to form a modified droplet, the first pulse of radiation having an energy sufficient to alter a shape of the target material droplet; directing a second pulse of radiation toward the modified droplet to form an absorption material, the second pulse of radiation having an energy sufficient to change a property of the modified droplet, the property being related to absorption of radiation; and directing an amplified light beam toward the absorption material, the amplified light beam having an energy sufficient to convert at least a portion of the absorption material into extreme ultraviolet (EUV) light.
US08653491B2	System, method and apparatus for aligning and synchronizing target material for optimum extreme ultraviolet light output An extreme ultraviolet light system and method includes a drive laser, a chamber including an extreme ultraviolet light collector and a target material dispenser including an adjustable target material outlet capable of outputting multiple portions of target material along a target material path. Also included: a drive laser steering device, a detection system including at least one detector and a controller coupled to the target material dispenser, the detector system and the drive laser steering device. The controller includes logic for detecting a location of the first portion of target material from the first light reflected from the first portion of target material and logic for adjusting the target material dispenser outlet to output a subsequent portion of target material to a waist of the focused drive laser. A system and a method for optimizing an extreme ultraviolet light output is also disclosed.
US08653489B2	Ion beam sample preparation apparatus and methods Disclosed are embodiments of an ion beam sample preparation apparatus and methods for using the embodiments. The apparatus comprises an ion beam irradiating means in a vacuum chamber that may direct ions toward a sample, a shield blocking a portion of the ions directed toward the sample, and a shield retention stage with shield retention means that replaceably and removably holds the shield in a position. The shield has datum features which abut complementary datum features on the shield retention stage when the shield is held in the shield retention stage. The shield has features which enable the durable adhering of the sample to the shield for processing the sample with the ion beam. The complementary datum features on both shield and shield retention stage enable accurate and repeatable positioning of the sample in the apparatus for sample processing and reprocessing. Additionally, apparatus kits are disclosed that enable the use of the same shields in the observation of prepared samples.
US08653486B2	Method and apparatus for improved uniformity control with dynamic beam shaping The present invention relates to a method and apparatus for varying the cross-sectional shape of an ion beam, as the ion beam is scanned over the surface of a workpiece, to generate a time-averaged ion beam having an improved ion beam current profile uniformity. In one embodiment, the cross-sectional shape of an ion beam is varied as the ion beam moves across the surface of the workpiece. The different cross-sectional shapes of the ion beam respectively have different beam profiles (e.g., having peaks at different locations along the beam profile), so that rapidly changing the cross-sectional shape of the ion beam results in a smoothing of the beam current profile (e.g., reduction of peaks associated with individual beam profiles) that the workpiece is exposed to. The resulting smoothed beam current profile provides for improved uniformity of the beam current and improved workpiece dose uniformity.
US08653485B2	Projection lens arrangement The invention relates to a charged particle multi-beamlet lithographic system for exposing a target using a plurality of beamlets. The system comprises a beamlet generator for generating a plurality of beamlets, a beamlet blanker for controllably blanking beamlets, and an array of projection lens systems for projecting unblanked beamlets on to the surface of the target. The beamlet generator comprises at least one charged particle source for generating a charged particle beam, a sub-beam generator for defining a plurality of sub-beams from the charged particle beam, a sub-beam manipulator array for influencing the sub-beams, and an aperture array for defining beamlets from the sub-beams.
US08653480B2	Imaging systems featuring waveguiding compensation In certain embodiments, the invention relates to systems and methods for altering an image to compensate for variation in one or more physical and/or supervenient properties (e.g., optical absorption and/or scattering) in heterogeneous, diffuse tissue, thereby attenuating the effects of tissue waveguiding. The methods enable the proper identification of emission image regions that evidence waveguiding of electromagnetic radiation, and enables compensation of emission images for such waveguiding. The methods preserve the depth localization accuracy of the FMT approach and improve optical reconstruction in the targeted areas while eliminating spurious components of fluorescence from the acquired data set. Calibration methods for probe concentration mapping are also presented.
US08653476B2	Specimen holder and specimen holder movement device The present disclosure significantly reduces the waiting time from inserting a specimen holder into an electron microscope until high quality data acquisition is possible. Characterizing the present disclosure, it is a specimen holder partly made of low thermal expansion material. The low thermal expansion material can be any of group 4, 5 or 6 in the periodic table of the elements.
US08653475B1	Ion source An arc chamber assembly for an ion source comprising a housing having a base and at least one pair of side walls extending upwardly from opposite sides of the base to define an arc chamber, the base having a plurality of channels extending to each sidewall; an inlet port connected to the base for delivering a flow of gas into the channels; a bottom liner having at least one pair of notches in each of two opposite side edges thereof and disposed in the housing in spaced parallel relation to the base and opposite the channels for conducting a flow of gas from the inlet port towards the sidewalls, each notch being in communication with a respective channel of the plurality of channels to pass gas upwardly into the arc chamber; and a pair of side liners, each side liner being disposed in the housing in spaced parallel relation to a respective one of the side walls for conducting a flow of gas between the base and the bottom liner, each side liner having at least one pair of slots to horizontally pass gas into the arc chamber.
US08653472B2	Electromagnetic field application system The present invention is based on the property that the electric and magnetic fields are independent of each other and normal to each other and the property that the deflection of a charged particle beam by the electromagnetic field follows the rule of linear combination. The present invention employs a system that creates a region in which there exist both electromagnetic field and controls the deflection of a charged particle beam in each of the electric and magnetic fields.
US08653469B1	K-alpha probe for detection of photon emissions A probe for detecting K-alpha photon emissions. A housing has an aperture at an end. A detector crystal is situated within the housing adjacent to the housing aperture. An energy conversion device is situated within the housing between the detector crystal and the aperture. The energy conversion device is made from a predetermined material configured to convert energy directed through the housing aperture from a source of primary photon emission radiation to a corresponding secondary K-alpha emission within a predetermined emission energy acceptance window. A power supply is coupled to the detector crystal and is configured to establish a polarized electrical field between the anode and the cathode of the detector crystal. The detector crystal receives the K-alpha emission and generates an electrical signal representative of the amount of target emissions received through the housing aperture.
US08653468B2	Radiological image conversion panel, method of manufacturing radiological conversion panel and radiological image detection apparatus A radiological image conversion panel includes a phosphor and a light transmissive protection material. The phosphor has a group of columnar crystals formed by growing a crystal of a fluorescent material and a fluorescence emitting surface configured by a set of tips of the columnar crystals. The light transmissive protection material covers the fluorescence emitting surface of the phosphor. The protection material is inserted between the tips of the group of the columnar crystals. A gap is formed between at least a part of a side of the tips of the columnar crystals and the protection material. The radiological image detection apparatus includes a radiological image conversion panel and a sensor panel that is provided close to the fluorescence emitting surface of the phosphor to detect the fluorescence emitted from the phosphor.
US08653467B2	Multichip packaging for imaging system A receiver chip for use in an imaging system includes a plurality of receiver dies, each of the receiver dies comprising one or more receiver circuits; a die interconnection layer located on top of the plurality of receiver dies; a quarter wave dielectric layer located on top of the die interconnection layer; and a plurality of antennae located on the quarter wave dielectric layer, each of the plurality of antennae corresponding to a respective receiver circuit, wherein the plurality of antennae are connected to the one or more receiver circuits through the quarter wave dielectric layer and the die interconnection layer by respective vias, such that a distance between a topmost layer of the die interconnection layer and the plurality of antennae is determined by a thickness of the quarter wave dielectric layer.
US08653464B2	Combination of single photon emission computed tomography and optical imaging detector The invention relates to an imaging method for simultaneously determining in vivo distributions of bioluminescent and/or fluorescent markers and radioactive markers at identical projection angles, the distribution of the bioluminescent and/or fluorescent markers being determined by separate detection of photons having a first average energy, which are emitted by the bioluminescent and/or fluorescent markers, by means of at least one first detector and the distribution of the radioactive markers being determined by simultaneous separate detection of photons having a second average energy, which are emitted by the radioactive markers, by means of at least one second detector. Furthermore, it also relates to an apparatus for carrying out the imaging method, containing at least one micro lens array optical tomographic imaging system as first detector, at least one single photon emission computer tomography (SPECT) detector as second detector.
US08653460B2	Method and system for detecting light A light detecting system is disclosed. The system comprises an arrangement of quantum dots forming an optically active region, a channel region and a charge carrier extractor between the active region and the channel region. The charge carrier extractor is characterized by a set of gradually decreasing energy levels between a characteristic excited energy level of the active region and a characteristic conductance energy level of the channel region.
US08653458B2	Charged particle beam device An inspection device carries out beam scanning on a stable scanning cycle by enabling flexible change of various scanning sequences according to inspection conditions thereof, and at the same time, eliminates as much unevenness as possible in scanning cycle which hinders stabilization of charging. A beam scanning scheduler schedules beam scanning based on an inputted scanning condition, and a programmable sequencer carries out beam scanning control according to a beam scanning schedule generated by the beam scanning scheduler. The scanning scheduler calculates scanning line reference coordinates on a scanning-line-by-scanning-line basis, based on the scanning condition, and issues a scanning cycle trigger. The programmable sequencer controls supply timing of the scanning line reference coordinates and a scanning position on an in-line pixel-by-pixel basis, based on line scanning procedure information and the scanning cycle trigger provided from the beam scanning scheduler.
US08653456B2	Pattern inspection method, pattern inspection program, and electronic device inspection system It is an object of the present invention to provide a technique capable of accurately inspecting a circuit pattern in which the contrast of an observation image is not clear, like a circuit pattern having a multilayer structure. A pattern inspection method according to the present invention divides a circuit pattern using the brightness of a reflection electron image and associates the region in the reflection electron image belonging to each division with the region in a secondary electron image.
US08653455B2	Charged particle beam device and evaluation method using the charged particle beam device The charged particle beam device has a problem that a symmetry of equipotential distribution is disturbed near the outer edge of a specimen, an object being evaluated, causing a charged particle beam to deflect there. An electrode plate installed inside the specimen holding mechanism of electrostatic attraction type is formed of an inner and outer electrode plates arranged concentrically. The outer electrode plate is formed to have an outer diameter larger than that of the specimen. The dimensions of the electrode plates are determined so that an overlapping area of the outer electrode plate and the specimen is substantially equal to an area of the inner electrode plate. The inner electrode plate is impressed with a voltage of a positive polarity with respect to a reference voltage and of an arbitrary magnitude, and the outer electrode is impressed with a voltage of a negative polarity and of an arbitrary magnitude.
US08653453B2	Mass discriminator An analysis device for mass discrimination is disclosed. The analysis device comprises: a sample chamber for holding a gaseous sample; an analysis chamber arranged to receive sample gas from the sample chamber; a mass discriminator arranged to discriminate in the analysis chamber between ion species generated from the sample gas; and a wall separating the sample chamber from the analysis chamber, the wall comprising a rupture zone controllable to rupture and thereby release sample gas from the sample chamber into the analysis chamber. In one embodiment the rupture zone is adapted to rupture on application of an electric current or mechanical force. The wall may be micromachined. A method of mass discrimination is also disclosed.
US08653451B2	Apparatus and method for time-of-flight mass spectrometry A flight-of-time mass spectrometer and method of flight-of-time mass spectrometry. The spectrometer includes a storage portion, a parameter adjusting portion, a parameter setting portion, and a flight time measuring portion. The parameter adjusting portion calculates values of an adjustment parameter correlated with any specified m/z value based on an adjustment table. The parameter setting portion sets the delayed extraction parameters of the ion source based on the values of the adjustment parameters calculated by the parameter adjusting portion.
US08653444B2	Calibration method A method and a calibration system for calibrating a measurement tool for measuring the radiation in a radiation system, such as a radiation therapy system, are provided. The measurement tool, including a holder and at least one photodiode element, is adapted to be mounted in a positioning unit of the radiation system. The radiation sensitive volume of the photodiode element is embedded in a light transparent coating transparent for, for instance, light in the visible spectrum. Thereby, the position of the sensitive volume can easily be determined or calculated with high accuracy relative to the holder on which the photodiode element is arranged, from which the position of the sensitive volume can be determined or calculated in relation to the positioning unit of the radiation system.
US08653440B2	Sensor and housing in a replicating system to facilitate detection of objects using electromagnetic radiation Exemplary embodiments can be used in a replicating system to guide source electromagnetic waves, such as infrared (IR) radiation, from an emitter of a reflective-type sensor towards an object held on a support mechanism and to guide reflected electromagnetic waves that are related to the source electromagnetic waves to a receiver of the reflective-type sensor. The height of the support mechanism can be adjusted based on whether the object is detected.
US08653438B2	Optical inputting module of an electronic device for sensing movement of object and its light source unit A light source unit is disclosed for arranging on a plane and emitting a light beam oblique to the plane. The light source unit includes an illuminant element and a transparent encapsulator. The illuminant element has an upper surface and a lower surface both parallel to the plane. The transparent encapsulator physically contacts with the illuminant element and at least covers the upper surface of the illuminant element. The transparent encapsulator has an oblique surface above the upper surface and oblique to the upper surface. In addition, an optical inputting module having the light source unit mentioned above is disclosed.
US08653435B2	Time-delay integration imaging method and apparatus using a high-speed in-pixel analog photon counter A high speed analog photon counter and method is provided. In one aspect, the method includes accumulating an electric charge in a capacitor of a circuit electrically coupled to a current source. The method further includes comparing the electric charge accumulated in the capacitor of the circuit with a reference voltage through a comparator of the circuit electrically coupled to an output of the capacitor. The method also includes increasing a speed of operation of a measurement device through implementing the circuit inside a pixel. The method further includes transferring the accumulated electric charge to a circuit of an adjacent pixel and synchronizing the transfer of the accumulated electric with a movement of an object captured by an image sensor device before implementing a time-delay integration operation.
US08653431B2	Photoelectric conversion device and image sensor There is provided a photoelectric conversion device utilizing surface plasmons, including: a plate-shaped light receiving portion which made of metal, provided on a most superficial surface of the photoelectric conversion device, and having a front surface and a rear surface so as to receive incident light at the front surface; a slot-shaped slit provided in the front surface of the light receiving portion; and a voltage detection portion adapted to measure an electric potential at the front surface of the light receiving portion; wherein the incident light is caused to excite surface plasmons through the slit, and an electric potential at the front surface of the light receiving portion induced by the surface plasmons is measured by the voltage detection portion.
US08653427B2	Digital semi-active laser receiver tracking of multiple line-of-sight (LOS) objects A digital SAL receiver implements a multiobject tracking method to detect EM pulses transmitted by a known source at a pulse repetition interval (PRI) and returned off of a target object to acquire multiple tracks. Intra and inter track temporal information is used to associate pulses with different tracks and to rank the tracks in order to designate a primary track for the target object.
US08653420B2	Temperature control circuit of oven controlled crystal oscillator A temperature control circuit of an oven controlled crystal oscillator (OCXO) is provided. A first and a second digital potentiometer are correspondingly arranged in a bridge circuit which outputs a voltage to an input terminal of a differential amplifier (OPAMP), wherein the resistance value of the first digital potentiometer is adjustable so as to adjust the temperature of the oven to the peak temperature of the crystal resonator, and the resistance value of the second digital potentiometer is adjustable so as to cancel the temperature gradient of the first digital potentiometer. In the temperature control circuit of OCXO, the heat generation of the heater resistor is controlled by the power transistor based on the control voltage from the differential amplifier.
US08653418B2	Device for connecting welding wire for CO2 gas welding A device for connecting welding wires for CO2 gas welding includes a base frame, first and second electrode plates that are disposed apart from each other on the base frame and including disposing grooves to which an old wire and a new wire are respectively disposed, and clampers that are disposed to each electrode plate and that clamp the used wire and the new wire disposed to the disposing grooves, respectively.
US08653410B2	Method of forming substrate for fluid ejection device A method of forming an opening through a substrate having a first side and a second side opposite the first side includes laser machining a first portion of the opening into the substrate from the second side toward the first side, and abrasive machining a second portion of the opening into the substrate. Abrasive machining the second portion of the opening into the substrate includes completing the opening through the substrate.
US08653408B2	Annealing apparatus using two wavelengths of continuous wave laser radiation A thermal processing apparatus and method in which a first laser source, for example, a CO2 emitting at 10.6 μm is focused onto a silicon wafer as a line beam and a second laser source, for example, a GaAs laser bar emitting at 808 nm is focused onto the wafer as a larger beam surrounding the line beam. The two beams are scanned in synchronism in the direction of the narrow dimension of the line beam to create a narrow heating pulse from the line beam when activated by the larger beam. The energy of GaAs radiation is greater than the silicon bandgap energy and creates free carriers. The energy of the CO2 radiation is less than the silicon bandgap energy so silicon is otherwise transparent to it, but the long wavelength radiation is absorbed by the free carriers.
US08653405B2	Method for operating a vacuum plasma process system In one aspect, operating a vacuum plasma process system including a plasma discharge chamber is accomplished by generating a main plasma in the discharge chamber in a first operating state, and generating an auxiliary plasma in the discharge chamber in a second operating state. Generating the main plasma includes generating a main plasma power with a first number of RF power generators, and generating an auxiliary plasma power with a second number of RF power generators, such that the second number is smaller than the first number.
US08653404B2	In-liquid plasma electrode, in-liquid plasma generating apparatus and in-liquid plasma generating method An in-liquid plasma electrode according to the present invention is an in-liquid plasma electrode for generating plasma in a liquid and has an electrically conductive member having an electric discharge end surface in contact with the liquid, and an electrically insulating member covering an outer periphery of the conductive member at least except the electric discharge end surface. Preferably, d and x satisfy −2d≦x≦2d, where d is a length of a minor axis of the cross section when a conductive end portion of the electrically conductive member having the electric discharge end surface has an approximately circular cross section, or d is a length of a short side of the cross section when the conductive end portion has an approximately rectangular cross section, and x is a distance from a reference plane to a plane containing the electric discharge end surface when the reference plane is an end surface of the electrically insulating member that is approximately parallel with the electric discharge end surface. Owing to this construction, it is possible to provide an in-liquid plasma electrode which can simply generate plasma in a wide variety of liquids including a conductive liquid such as water and alcohol, and furthermore an in-liquid plasma generating apparatus having this electrode, and an in-liquid plasma generating method using this electrode.
US08653403B2	Butt-welded joint and method for manufacturing same A butt-welded joint includes a pair of steel plates, a first weld metal that is formed at a butting portion of the pair of steel plates from a side of a first surface of the butt-welded joint to a side of a second surface opposite the first surface by irradiation of a first high-energy density beam from the side of the first surface, and a second weld metal that is formed by irradiation of a second high-energy density beam to cover an end surface of the first weld metal at the side of the first surface side of the first weld metal. A width W1 of the first weld metal on the first surface and a width W2 of the second weld metal on the first surface satisfy an equation 1.2≦W2/W1≦3.5, and a depth of the second weld metal from the first surface is 2.0 mm to 10.0 mm.
US08653400B2	High strength welded steel tube superior in hydrogen embrittlement cracking resistance of weld metal and method of production of same The present invention provides a high strength welded steel pipe superior in weld zone embrittlement crack characteristics and a method of production of the same, that is, a method of production of a welded steel pipe superior in hydrogen embrittlement cracking resistance of weld metal characterized by seam welding from the inner and outer surfaces by a tensile strength of 850 MPa or more, then expanding or reducing the size of the pipe for correction, which method of production of welded steel pipe characterized in that the hydrogen concentration of the preceding weld metal is 0.2 cc or less per 100 g at ordinary temperature.
US08653397B2	Contact apparatus for circuit breaker Disclosed herein is a contact apparatus for a circuit breaker, and the circuit breaker may include a stationary electrode portion having a stationary contact; and a movable electrode portion configured to be brought into contact with and separated from the stationary electrode portion, wherein the movable electrode portion includes a movable conductor portion configured to be approached to and spaced from the stationary electrode portion; and a movable contact combined with the movable conductor portion in a relatively movable manner to be brought into contact with and separated from the stationary contact. Through this, it may be possible to alleviate a shock when contacting a contact.
US08653394B2	Electrostatic separation method and electrostatic separation device The present invention provides an electrostatic separation method and an electrostatic separation device each of which, even in a case where the concentration of unburned components of coal ash produced by a boiler of a coal-fired power plant is as high as 15% to 30%, can stably separate the ash without generating spark, reuse the high unburned component ash as fuel, and reuse the low unburned component ash as, for example, an auxiliary material of concrete. The electrostatic separation device may include a substantially flat plate lower side electrode and an upper side electrode including a high dielectric resin element. A separation zone is formed in a region of electrostatic force between the lower side electrode and the upper side electrode, with one of the electrodes having positive polarity and the other having negative polarity. Unburned carbon ash in the coal ash supplied to the separation zone is separated.
US08653393B2	Touch screen panel A touch screen panel according to an embodiment includes a substrate; an electrode forming part formed on the substrate, the electrode forming part including a plurality of first electrode serials arranged in parallel in a first direction and a plurality of second electrode serials arranged in parallel in a second direction to cross over the plurality of first electrode serials; a routing wire forming part formed on the substrate outside the electrode forming part, the routing wire forming part including a plurality of first routing wires respectively connected to the plurality of first electrode serials and a plurality of second routing wires respectively connected to the plurality of second electrode serials; and an insulation layer configured to insulate the first electrode serial from the second electrode serial at each of intersections of the first electrode serials and the second electrode serials.
US08653392B2	Handpiece finger switch for actuation of handheld medical instrumentation A handpiece for a medical instrumentation device is formed with manually deformable ribs on an outer sleeve. The ribs align with conductive surfaces inside the handpiece that make contact with an internal flexible electronic circuit to activate the device when force is applied to the ribs. Removing the force deactivates the device.
US08653390B2	Engine start/stop switch for a vehicle An engine start/stop switch for a vehicle is provided, including a housing having one end portion exposed outwardly from a dashboard and the other end portion embedded in the dashboard; a button disposed in the housing and having one end portion exposed outwardly to be pressed to start or stop an engine; a slider disposed at the front end of the button to be slid along the inner peripheral surface of the housing; a circuit unit disposed to closely contact the front end of the slider to be electrified when pressed by the slider and to generate an engine start or stop signal; and a coil antenna interposed between the button and the slider to transmit driving waves to the transponder of a portable device carried by a driver. Further, the housing includes first and second housings detachably coupled to each other to encompass the button, slider and circuit unit.
US08653388B2	Switch devices for power tools A switch device for a power tool includes a switch case and a switch lever. The switch lever extends outwardly from within the switch case. The switch lever has a rotative portion rotatably supported by a support portion of the switch case. A waterproofing member is disposed between the rotative portion and the support portion and provides a waterproof seal therebetween.
US08653386B2	Cutting apparatus, breaker, contactor, and electrical circuit breaker A blade (11), which includes a cutting portion (21) and an insulating portion (22), is used as a blade (11) of a cutting apparatus (10). The cutting portion (21) is made of a metal, and has a blade portion. The insulating portion (22) is formed by an insulating member, and forms a part that adjoins the blade portion in a direction opposite to an advance direction of the blade (11). The cutting apparatus (10) is configured so that, when cutting a current-carrying member (15), the blade (11) advances until the insulating portion (22) contacts cut faces of the current-carrying member (15) after the cutting portion (21) cuts the current-carrying member (15).
US08653381B2	Wiring board comprising wirings arranged with crest and trough A wiring board includes: a first wiring; a second wiring being disposed adjacently to the first wiring; a third wiring being disposed adjacently to the first wiring; a fourth wiring being disposed adjacently to the third wiring; and an insulating layer, wherein the second wiring and the fourth wiring are disposed adjacently to each other, the first wiring and the fourth wiring are not overlapped, the second wiring and the third wiring are not overlapped, a crest and a trough are provided on a side face of the first wiring, the crest and the trough are provided on a side face of the second wiring, the trough provided on the side face of the first wiring and the third wiring are overlapped, and the trough provided on the side face of the second wiring and the fourth wiring are overlapped.
US08653375B2	Mitigation of whiskers in Sn-films An electronic device includes a metallic conducting lead having a surface. A pre-solder coating over the surface consists essentially of tin and one or more dopants selected from Al or a rare earth element.
US08653374B2	Aluminum alloy wire An aluminum alloy wire, an aluminum alloy stranded wire, a covered electric wire, and a wire harness that are of high toughness and high electrical conductivity, and a method of manufacturing an aluminum alloy wire. The aluminum alloy wire contains not less than 0.2% and not more than 1.0% by mass of Mg, not less than 0.1% and not more than 1.0% by mass of Si, not less than 0.1% and not more than 0.5% by mass of Cu, and a remainder including Al and an impurity, and satisfies 0.8 Mg/Si≦2.7 by mass ratio. The Al alloy wire is manufactured through the successive steps of casting, rolling, wiredrawing, and softening treatment.
US08653370B2	Cable and method of making the same Cable having a stress parameter less than 0 MPa and method for cable. The cable has a longitudinal core having a thermal expansion coefficient; and a plurality of wires collectively having a thermal expansion coefficient greater than the thermal expansion coefficient of the core. The plurality of wires, which are stranded around the core, include at least one of aluminum wires, copper wires, aluminum alloy wires, or copper alloy wires. Embodiments of the cable are useful, for example, as an overhead power transmission line.
US08653367B2	Spherical cap for high-voltage outgoing lines in oil transformers The disclosure relates to a spherical cap for a high-voltage outgoing line, including an electrically conductive element, which is arranged hollow-cylindrically about a rotational axis and which merges into a hemispherical form at its first axial end. A connection device has a passage opening for electrically and mechanically connecting the element, to an electrical screening pipe. At least two insulation barriers are spaced apart from one another and respectively adapted to the form of the hollow-cylindrical element and enclose the latter at a respective first and second distance. The insulation barriers respectively have a pipe attachment connector for leading through a screening pipe to the connection device. The first insulation barrier is spaced apart from the second insulation barrier by at least one insulation ring which is arranged about the rotational axis and which has a radially fashioned corrugated form.
US08653363B2	Magnetic filler panel for use in airflow control system in electronic equipment enclosure An electronic equipment enclosure system with an airflow control system includes an enclosure, having a front, a rear, a top, a bottom and two sides, and a magnetic filler panel.
US08653359B2	Solar energy device and using method of the same A solar energy device including at least one solar energy module and a connecting structure is provided. The connecting structure includes a body and a connecting belt. The body assembled to the solar energy module has a recess. The connecting belt has a first end, a second end, and a connecting protruding configured at the second end, wherein the first end connects to the body. A using method of the solar energy module is also provided.
US08653356B2	Thermoelectric devices and methods of manufacture Thermoelectric devices are provided. In one embodiment, a thermoelectric device may include a glass wafer defined by conductive vias, a second wafer, and a plurality of metal film disposed between the glass wafer and the second wafer and against solid, conductive, integral, end surfaces of the conductive vias. A nanogap may be disposed between the metal film and the second wafer. The nanogap may have been created by applying a voltage extending between the conductive vias and the second wafer. Methods of forming the devices, along with methods of using the devices to transform heat energy to electricity, and for refrigeration, are also provided.
US08653354B1	Audio synthesizing systems and methods A system and method is disclosed teach how to synthesizing audio. It allows specification of a musical sound to be generated. It synthesizes an audio source, such as noise, using parameters to specify the desired frequency slit spacing and the desired noise-to-frequency band ratio, then filtering the audio source through a sequence of filters to obtain the desired frequency slit spacing and noise to frequency band ratio. It allows modulation of the filters in the sequence. It outputs musical sound.
US08653353B2	Electronic keyboard musical instrument An electronic keyboard musical instrument, including: a key; a mass body driven by a depressed key for pivotally moving in a movement region between a rest position and an end position; a back check portion to back check the mass body; a position detecting portion to detect a position of the mass body; and a controller for controlling silencing of a tone, such that the currently generated tone is silenced when the mass body reaches a preset tone silencing position in its movement from the end position to the rest position, wherein the controller is configured to change the tone silencing position on the basis of respective times required for the mass body to pass through first and second sub regions of the movement region in the movement of the mass body, the second sub region being located nearer to the rest position than the first sub region.
US08653351B2	Systems for combining inputs from electronic musical instruments and devices An apparatus for combining input signals produced by a plurality of electric musical devices includes a plurality of audio buses and a plurality of segments. Each segment includes input circuitry configured to receive at least one input signal from at least one electric musical device and to deliver the at least one input signal to one of the plurality of audio buses; a plurality of variable adjustment devices each associated with a corresponding one of the audio buses and each configured to change at least one property of an input signal received by another of the plurality of segments and carried on the corresponding one of the audio buses independent from input signals carried on other of the plurality of audio buses; and a mixer configured to combine the input signals carried on each of the plurality of audio buses into an output signal.
US08653350B2	Performance apparatus and electronic musical instrument A performance apparatus 11 extends in a longitudinal direction to be held by a player, and is provided with an acceleration sensor 23. CPU 21 of the performance apparatus 11 gives a sound source unit 31 of a musical instrument unit 19 an instruction (note-on event) to generate a musical tone. CPU 21 generates a note-on event indicating a sound-generation timing represented by a time when an acceleration-sensor value of the acceleration sensor 23 exceeds a first predetermined value and thereafter has decreased to a value less than a second threshold value β, which is less than a first threshold value α, and gives the musical instrument unit 19 the generated note-on event to generate a musical tone.
US08653344B2	Variety corn line NPFX7687 The present invention provides an inbred corn line designated NPFX7687, methods for producing a corn plant by crossing plants of the inbred line NPFX7687 with plants of another corn plant. The invention further encompasses all parts of inbred corn line NPFX7687, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line NPFX7687, and plants produced according to these methods.
US08653340B2	Soybean variety A1026361 The invention relates to the soybean variety designated A1026361. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026361. Also provided by the invention are tissue cultures of the soybean variety A1026361 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026361 with itself or another soybean variety and plants produced by such methods.
US08653338B2	Soybean variety XB25G12 A novel soybean variety, designated XB25G12 is provided. Also provided are the seeds of soybean variety XB25G12, cells from soybean variety XB25G12, plants of soybean XB25G12, and plant parts of soybean variety XB25G12. Methods provided include producing a soybean plant by crossing soybean variety XB25G12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB25G12, methods for producing other soybean varieties or plant parts derived from soybean variety XB25G12, and methods of characterizing soybean variety XB25G12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB25G12 are further provided.
US08653337B2	Soybean variety XR22N12 A novel soybean variety, designated XR22N12 is provided. Also provided are the seeds of soybean variety XR22N12, cells from soybean variety XR22N12, plants of soybean XR22N12, and plant parts of soybean variety XR22N12. Methods provided include producing a soybean plant by crossing soybean variety XR22N12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XR22N12, methods for producing other soybean varieties or plant parts derived from soybean variety XR22N12, and methods of characterizing soybean variety XR22N12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XR22N12 are further provided.
US08653330B2	Compositions and methods for altering the morphology of plants Compounds, methods for producing them and methods for varying the morphology of plants are disclosed. More particularly, a SUN gene can be used to alter the shape of fruit in a plant such as a tomato plant.
US08653328B2	Plant genes associated with seed oil content and methods of their use Cytochrome b5 (Cb5) is a haem-binding protein located in the endoplasmic reticulum (ER) and the outer mitochondrial membranes of higher eukaryotes. In higher plants, animals, and fungi, the ER resident Cb5 has been shown to play a role in desaturation of acyl CoA fatty acids. Higher plants Cb5 isoforms from plants such as soybean or Arabidopsis are capable of modulating omega-3 desaturation. Co-expression of certain Cb5 isoforms with FAD3 in a host plant results in increased production of seed oil content as well as altered ratio between different fatty acids. It is also disclosed here that overexpression of Yarrowia ACL enzymes in the plastids of a host plant helps boost the synthesis of acetyl CoA, which in turn, may lead to increased synthesis of fatty acids and enhanced oil accumulation in the seeds.
US08653317B2	Dehydrogenation process and catalyst A supported catalyst and process for dehydrogenating a hydrocarbon, the catalyst comprising a first component selected from the group consisting of tin, germanium, lead, indium, gallium, thallium, and compounds thereof; a second component selected from the group consisting of metals of Group 8 of the Periodic Table of the Elements and compounds thereof, and a support comprising alumina in the gamma crystalline form. The catalysts are especially active and efficient when employed in concurrent flow in a dehydrogenation reactor having an average contact time between the hydrocarbon and catalyst of from 0.5 to 10 seconds.
US08653315B2	Multiple zeolite catalyst and method of using the same for toluene disproportionation The multiple zeolite catalyst is a catalytic composition used to convert alkylaromatic hydrocarbons to BTX, particularly to commercially valuable xylenes. The catalyst is formed by mixing at least two zeolites selected from mordenite, beta zeolite, ZSM-5, ZSM-11, ZSM-12, ZSM-22, ZSM-23, MFI topology zeolite, NES topology zeolite, EU-1, MAPO-36, SAPO-5, SAPO-11, SAPO-34, and SAPO-41, and adding at least one metal component selected from Group VI of the Periodic Table of the Elements. The two zeolites have different physical and chemical characteristics, such as pore size and acidity. An exemplary catalyst includes mordenite, ZSM-5, and 3 wt % molybdenum. The multiple zeolite catalyst may further be used to convert toluene to mixed xylene isomers, particularly with a ZSM-5:mordenite ratio of 2:1 by weight.
US08653313B2	Process for preparing a phenylcyclohexane The present invention relates to an improved process for preparing a substituted or unsubstituted phenylcyclohexane by catalytic hydrogenation of a substituted or unsubstituted biphenyl.
US08653312B2	Method for producing water-insoluble liquefied fuel oil from biomass Provided herein is a method for producing a water-insoluble liquefied fuel oil containing a hydrocarbon from biomass. The method includes converting an oxygen-containing compound in a liquefied fuel oil obtained after liquefaction to a hydrocarbon and converting a water-soluble organic substance contained in an aqueous phase to a hydrocarbon, thereby improving the yield of the water-insoluble liquefied fuel oil.
US08653311B2	Azeotrope-like composition of hexafluoropropane, hexafluoropropene and hydrogen fluoride The present invention relates to an azeotropic or azeotrope-like mixture consisting essentially of 1,1,1,2,3,3-hexafluoropropane, hexafluoropropene and hydrogen fluoride.
US08653309B2	Process for producing trans-1233zd Trans-1233zd, the trans-isomer of 1-chloro-3,3,3-trifluoropropene (HCFO-1233zd) can be used as blowing agents, solvents, cleaning agents, as well as monomers of macromolecule compounds, and can be prepared through the dehydrochlorination of 1,1,1-trifluoro-3,3-dichloropropane (HCFC-243fa) with the help of a catalyst. The present invention is directed to an integrated process is proposed to produce trans-1233zd from 243fa, which is consisted of the following four major unit operations: (1) Catalytic dehydrochlorination of 243fa into trans/cis-1233zd, (2) HCl recovery, (3) Catalytic isomerization of cis-1233zd into trans-1233zzd, and (4) Isolation of trans-1233zd.
US08653305B2	Compound having S1P receptor binding potency and use thereof Provided are: a compound represented by formula (I): (wherein ring A and ring D each represent a cyclic group which may have a substituent(s); E and G each represent a bond or a spacer having 1 to 8 atoms in its main chain; L represents a hydrogen atom or a substituent; X represents amino which may have a substituent(s), or a heterocylcic group which contains at least one nitrogen atom and which may have a substituent(s); n represents 0 to 3, and when n is 2 or more, a plurality of ring A's may be the same or different from one another); a salt, an N-oxide form, a solvate, or a prodrug thereof; and a medicament which includes those. The compound of formula (I) is capable of binding S1P receptors (in particular, EDG-1 and/or EDG-6), and useful for preventing and/or treating rejection in transplantation, autoimmune diseases, allergic diseases, etc.
US08653304B2	2,3-dihydro-1H-indene-2-yl urea derivative and pharmaceutical application of same A 2,3-dihydro-1H-indene-2-yl urea represented by Formula (Ia) or a pharmaceutically acceptable salt thereof:
US08653303B2	Processes for preparing acetic anhydride In one embodiment, the invention is to a process for producing acetic anhydride. The process includes at least a step of carbonylating methanol and/or a methanol derivative with carbon monoxide to form acetic acid, and contacting ketene with the acetic acid to form a crude acetic anhydride product stream and a vent stream having unreacted ketene. The process further comprises a step of directing at least a portion of the vent stream to a liquid ring vacuum compressor having a ring seal fluid comprising acetic acid The unreacted ketene in the portion of the vent stream contacts the ring seal fluid to form supplemental acetic anhydride.
US08653299B2	Dihydronaphthalene and naphthalene derivatives as N-formyl peptide receptor like-1 (FPRL-1) receptor modulators The present invention relates to novel dihydronaphthalene and naphthalene derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the N-formyl peptide receptor like-1 (FPRL-1) receptor.
US08653295B2	Process for producing α-trifluoromethyl-α,β-unsaturated ester An α-trifluoromethyl-α,β-unsaturated ester can be produced by reacting an α-trifluoromethyl-α-hydroxy ester with sulfuryl fluoride (SO2F2) in the presence of an organic base. It is preferable that the raw substrate has a hydrogen atom as one β-position substituent group and either an alkyl group, a substituted alkyl group, an alkenyl group, a substituted alkenyl group, an aromatic ring group or a substituted aromatic ring group as the other β-position substituent group. It is more preferable that an ester moiety of the raw substrate is an alkyl ester. This raw substrate is readily available. Further, the desired reaction can proceed favorably with the use of this raw substrate. It is also preferable to use either 1,5-diazabicyclo[4.3.0]non-5-ene (DBN) or 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) as the organic base. The desired reaction can proceed more favorably with the use of this organic base.
US08653291B2	Method for surface functionalization by disubstituted alkynes The invention relates to the use of disubstituted alkynes for the functionalisation of the surface of a substrate consisting of a semi-conductor material, with molecules of interest. According to the invention, a compound of formula A-(E1)n1-F1 is used, wherein A is a linear or cyclic disubstituted alkyne, E1 is an alkyl chain and n2 is 0 or 1, and F1 is a reactive group that can react with the reactive group F2 of a compound of formula F2-(E2)n2-X wherein E2 is an alkyl chain and X is a group having properties of interest. The invention is especially applicable to the field of molecular biology or biotechnology.
US08653289B2	Partial esters of a polyglycerol with at least one carboxylic acid and one polyfunctional carboxylic acid, their preparation and use The present disclosure relates to specific (poly-)glycerol partial esters with at least one carboxylic acid and one polyfunctional carboxylic acid, and to the use thereof as emulsifier and to formulations comprising partial esters of the present disclosure.
US08653288B2	Deodorized edible oil or fat with low levels of bound MCPD and process of making by carboxymethyl cellulose and/or resin purification A process for making a deodorized edible oil or fat having a low level of bound MCPD (monochloro propanediol esters) and/or low level of bound 3-MCPD is described. The process comprises a step of contacting the oil or fat to a carboxymethyl cellulose or an ion exchange resin. The carboxymethyl cellulose can be a Blanose® cellulose gum and the resin can be a cationic resin. A deodorized vegetable oil or fat and a food product made there from is described. The food product can be an infant formula. It exhibits low levels of bound MCPD and/or low level of bound 3-MCPD. In one embodiment the oil or fat has a reduced level of free fatty acid as well as a limpid aspect and no off-flavors.
US08653281B2	Process for the manufacture of agomelatine and its intermediate A process for the manufacture of agomelatine and its intermediate N-[2-(7-methoxy- 1-naphthy)ethyl]phthalimide is provided and inclues reacting 7-methoxy-1-naphthyl ethanol (III) with benzenesulfonyl chloride to obtain 7-methoxy-1 -naphthylethyl benzene sulfonate (IV), which is reacted with potassium phthalimide to produce N-[2-(7-methoxy-1-naphthy)ethyl]phthalimide (II); and subjecting N-[2-(7-methoxy-1-naphthy)ethyl]phthalimide (II) to alkaline hydrolysis and acetylation, to obtain agomelatine.
US08653280B2	Process for the preparation of asenapine The present invention is directed to novel compounds of formula (I) as well as to the process for their preparation. Novel compounds of formula (I) can be converted into asenapine through an efficient process. The invention also relates to novel intermediates used in this process and their use in the preparation of compounds of formula (I).
US08653278B2	Isoform selective HDAC inhibitors One aspect of the invention relates to isoform-selective HDAC inhibitors. Also provided are methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy. The invention also provides methods for treating cancer, methods for treating neurological diseases and methods for treating malaria. Additionally, the invention provides pharmaceutical compositions comprising an HDAC inhibitor of the invention; and kits comprising an HDAC inhibitor of the invention.
US08653272B2	Fused pyridine derivatives as kinase inhibitors A series of heteroaryl-substituted fused pyridine derivatives, in particular heteroaryl-substituted thieno[3,2-6]pyridine derivatives, being selective inhibitors of PO kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
US08653269B2	Process for preparation of t-butoxycarbonylamine compounds Provided is a process for the preparation of t-butoxycarbonylamine compounds, which comprises using phosgene or a phosgene equivalent, t-butanol, and an organic base. Even when applied to a primary or secondary amine compound having low nucleophilicity, the process enables highly selective preparation of a t-butoxycarbonylamine compound at a low cost. In the process, a t-butoxycarbonylamine compound is prepared using: phosgene or a phosgene equivalent; t-butanol; an organic base; and either a primary or secondary amine compound or a primary or secondary ammonium salt.
US08653265B2	Preparation method of rosuvastatin calcium and its intermediates A preparation method of rosuvastatin calcium (Formula 1), which can be used for the production of medicament lowering the levels of LDL-cholesterol and triglycerides in vivo, is provided. Such preparation method is suitable for industrial production. Furthermore, the intermediate crystallines used in the preparation method are provided.
US08653262B2	CCR2 receptor antagonists and uses thereof The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD.
US08653261B2	Modified actinomycin-based nucleic acid stains and methods of their use Actinomysin-based near IR emitting compounds and methods of their use as nucleic acid stains are provided. The actinomysin-based near IR emitting compounds have the structure: wherein R is H or NH2; R1, R2, R3, and R4 are independently a moiety comprising 1-30 atoms selected from H, O, C, and N, wherein the atoms are in a linear, branched, or cyclic configuration; R3 and/or R4 comprise a quaternary nitrogen atom; and R5 is H, F, or Cl.
US08653259B2	Process for synthesizing heterocyclic compounds The invention provides the process illustrated in scheme 1 for synthesizing heterocyclic compounds of formula I. In the process, an isothiocyanate of formula II is initially reacted with a primary amine or formula III to give a thiourea of formula IV. Subsequently, the thiourea of formula IV is converted to the corresponding heterocycle of formula I using a base and a sulfonyl chloride.
US08653257B2	Dibenzothiazepine derivatives and uses thereof—424 Compounds the following formula: wherein Z is as described in the specification, pharmaceutically acceptable salts thereof, compositions comprising the same, and methods of treating bipolar disorder, an anxiety disorder, a mood disorder or schizophrenia or other psychotic disorder with said compounds.
US08653249B2	Expression vector for mass production of foreign gene-derived protein using animal cell and use thereof The present inventors successfully constructed expression vectors that enable high-level production of foreign gene-derived proteins in mammalian host cells, which comprise a translation-impaired drug resistance gene cistron whose expression has been attenuated by altering the codons to the least frequently used codons in mammals; and a gene cassette which has a cloning site for incorporation of a foreign gene between a highly transcriptionally active promoter and a highly stable polyadenylation signal.
US08653247B2	Rinsable dyes and methods for their preparation Rinsable dyes with improved fugitivity are formulated by attaching dyestuff compounds with amine-capped sulfonic solubilizing groups to commercially available ethoxylated aniline, so that the surfactant effect of the ethoxylated aniline counteracts the substantivity of the dyestuff compound, while the neutralization of the sulfonic solubilizing groups reduces substantivity.
US08653246B2	Method for purifying protein The present invention provides a method for purifying a protein to remove impurities from a mixture liquid containing a desired protein and the impurities, comprising the step of performing filtration using a porous membrane having a graft chain on a pore surface and an anion-exchange group fixed to the graft chain.
US08653245B2	Methods for purification of alpha-1-antitrypsin and apolipoprotein A-1 This invention relates to protein separation and purification methods for both alpha-1-antitrypsin (AAT, also known as alpha-1 proteinase inhibitor, API, and A.sub.1-PI) and Apolipoprotein A-I (ApoA-1) from, for example, a fraction of human blood plasma. In certain embodiments, the invention provides methods for separating AAT from ApoA-1 at the initial stage of purification, so that the same starting material can be used as a source for both proteins. The methods further pertain to providing compositions of AAT and of ApoA-1 suitable for pharmaceutical use and are suitable for large-scale purification.
US08653243B2	Pertussis antibodies and uses thereof Compositions and methods are provided that are useful to treat respiratory diseases such as whooping cough. Further, compositions and methods of immunizing are provided.
US08653239B2	Method for isolating polypeptides The present invention relates to a method for isolating and/or purifying at least one polypeptide from a polypeptide-containing sample, characterized in that the sample is contacted with a boron carbide support material at a pH which allows the binding of the polypeptide to the boron carbide support material. Such isolating can, for example, be used to remove polypeptides from a sample or else to purify and/or to concentrate polypeptides. A matrix comprising a boron carbide support material for purification of polypeptides is further disclosed according to the invention.
US08653238B2	Compositions and methods for transport of molecules with enhanced release properties across biological barriers Conjugates of a cargo molecule with a transporter molecule are disclosed, where the cargo molecule and the transporter molecule are linked covalently by a releasable linker. The cargo of the conjugate can be a biologically active agent or a reporter molecule. The transporter modulates the transport of the cargo across a biological barrier (e.g., a cell membrane) compared to the transport of the unconjugated cargo. Releasable linkers suitable for rapid and facile conjugation to various types of cargo and transporters are also disclosed, along with methods for using the linkers in the synthesis of conjugates.
US08653237B2	Peptide analogues Some embodiments relate to analogs of peptides corresponding to class I MHC-restricted T cell epitopes and methods for their generation. These analogs can contain amino acid substitutions at residues that directly interact with MHC molecules, and can confer improved, modified or useful immunologic properties. Additionally, classes of analogs, in which the various substitutions comprise the non-standard residues norleucine and/or norvaline, are disclosed.
US08653236B2	Therapeutic agents A purified anti-cancer peptide consisting of amino acids 266 to 287 of Genbank Accession No. O68604 (SEQ ID No. 4), and modified and homologous forms of the peptide are described. The modified or and homologous forms of the peptide include more than contiguous amino acids having at least 75% amino acid sequence identity with at least 8 contiguous amino acids of amino acids 266-287 of Genbank Accession No. O68604 (SEQ ID No. 4) defining a motif selected from the group consisting of RRRVQQ (SEQ ID No. 5) and RGRAK (SEQ ID No. 1). The peptide(s) can be produced by B. linens, a Brevibacterium commonly used in the production of cheese. There is also provided method for prophylaxis or treatment of cancer in a mammal, comprising treating the mammal with an effective amount of the peptide, or a protein the pepsin cleavage of which yields the peptide.
US08653233B2	Compositions and methods for preventing or treating cancer The present invention relates to a MUC1 cytoplasmic tail peptide or portion thereof. These peptides are useful for inducing an immune response to MUC1-expressing tumor cells and thus for preventing or treating cancer.
US08653232B2	Manufacturing method of polyethylene terephthalate A manufacturing method of polyethylene terephthalate including a step of melt polycondensation in presence of polycondensation catalyst represented by general Formula (I), wherein R1 represents an alkyl group having from 2 to 12 carbon atoms, and melt polycondensed polyethylene terephthalate has an intrinsic viscosity of from 0.48 to 0.53 dL/g and a terminal carboxyl number of from 14 to 22 mmol/kg; and a step of solid phase polycondensation to obtain solid phase polycondensed polyethylene terephthalate having an intrinsic viscosity of from 0.70 to 0.86 dL/g, and a terminal carboxyl number of less than 15 mmol/kg, followed by a step of applying an aqueous solution of at least one salt selected from the group consisting of acetate, carbonate, and sulfate of sodium, potassium, or cesium to the solid phase polycondensed polyethylene terephthalate, and then drying the polyethylene terephthalate, wherein the final content of sodium, potassium or cesium atom in dried polyethylene terephthalate is from 2 to 25 ppm.
US08653228B2	Semiconducting polymers Novel Semiconducting photovoltaic polymers with conjugated units that provide improved solar conversion efficiency that can be used in electro-optical and electric devices. The polymers exhibit increased solar conversion efficiency in solar devices.
US08653227B2	Process for preparing regioregular poly-(3-substituted) thiophenes, selenophenes, thiazoles and selenazoles A process for preparing a regioregular homopolymer or copolymer of 3-substituted thiophene, 3-substituted selenophene, 3-substituted thiazol or 3-substituted selenazol by a) reacting a 3-substituted 2,5-dihalothiophene, 2,5-dihaloselenophene, 2,5-dihalothiazol or 2,5-dihaloselenazol with reactive zinc, magnesium and/or an organomagnesium halide to give an organozinc or organomagnesium intermediate containing one halozinc or one halomagnesium group, b) bringing the organozinc or the organomagnesium intermediate into contact with a Ni(II), Ni(O), Pd(II) or Pd(0) catalyst to initiate the polymerization reaction, and c) polymerizing the organozinc or the organomagnesium intermediate to give a regioregular head-to-tail homopolymer or copolymer of 3-substituted thiophene, 3-substituted selenophene, 3-substituted thiazol or 3-substituted selenazol characterized in that the polymerization reaction is carried out at a temperature rising from a lower temperature T1 to a higher temperature T2 during a time t1, wherein T1 is in the range of from −40 to 5° C. and T2 is in the range of from −20 to 40° C., wherein T2−T1 is at least 10° C. and the average rate of increase (T2−T1)/t1 is in the range of from 0.05° C./min to 1° C./min.
US08653224B1	Resin composition for manufacturing thermoplastic polyester resin by using green catalyst Provided is a composition for manufacturing a polyester resin having a molar ratio of a diol compound to a dicarboxylic acid compound ranging from 1.05 to 1.4, in which the composition includes 5 ppm to 50 ppm of a phosphorous (P) compound (based on an amount of P), 10 ppm to 40 ppm of a cobalt (Co) compound (based on an amount of Co), 0.2 ppm to 20 ppm of a color enhancer, and 5 ppm to 25 ppm/3 ppm to 30 ppm of a titanium (Ti)-germanium (Ge) composite catalyst compound (based on an amount of Ti/Ge), based on weight percentage.
US08653223B2	Transketalized compositions, synthesis, and applications Ketal compounds of the structure I and a method of preparation of the compound from polyols and oxocarboxylates, as well as uses thereof.
US08653219B2	Method for producing reactive polyurethane compositions Proposed is a process for preparing a reactive polyurethane composition that is characterized in that in a first process stage, from an isocyanate-reactive polymer or mixture of isocyanate-reactive polymers with a fraction of at least 90%, preferably at least 95%, more preferably at least 99% by weight of linear molecules, by reaction with a polyisocyanate having a molecular weight <500, in a molar deficit of the isocyanate groups of the polyisocyanate relative to the isocyanate-reactive end groups of the polymer or mixture of polymers, a monomer-free thermoplastic polyurethane is prepared which in a second process stage is reacted with a low-monomer-content, isocyanate-terminal prepolymer, in a molar ratio of the isocyanate-reactive end groups of the thermoplastic polyurethane to the isocyanate groups of the prepolymer of 1:1.1 to 1:5, to give the isocyanate-reactive polyurethane composition.
US08653214B2	Silicone (meth)acrylate particles, process for preparation thereof and use thereof The present invention relates to silicone (meth)acrylate particles, to a process for preparing such silicone (meth)acrylate particles including the steps of: a) obtaining an emulsion composed of water and an organic phase comprising organopolysiloxanes modified terminally and/or laterally with acrylate groups, and b) polymerizing the inner phase to completion by means of a free-radical initiator, the free-radical initiator being added to the outer phase (aqueous phase) in a concentration of 0.1 to 40% by weight based on the inner phase, and to the use of the particles alone or in a mixture with further particles, pigments and/or further customary additives in the form of powders or dispersions in coating, adhesive or sealant materials, in polymers, in defoamers, in wetting and levelling aids, in cosmetic or pharmaceutical formulations and care products, in cleaning and detergent compositions, or in applications for modifying the interface properties of solid and liquid substrates, for example tactile properties, hydrophobization, or sliding and/or release properties.
US08653211B2	Random copolymer for forming neutral surface and methods of manufacturing and using the same A random copolymer having a structure represented by the following Formula 1: wherein R is phosphonic acid, Me is a methyl group, x is a number of styrene units, and y is a number of methyl methacrylate units.
US08653206B2	Operation of multi-reactor polyolefin manufacturing process The invention relates to an improved process for manufacturing an olefin polymer composition, in particular polyethylene, that incorporates two or more reaction zones in an optimized configuration that ease product transitions and allows for improved reactor quality control.
US08653205B2	Resin composition for encapsulating semiconductor and semiconductor device Disclosed is a resin composition for encapsulating a semiconductor containing an epoxy resin (A), a curing agent (B), and an inorganic filler (C), wherein the epoxy resin (A) includes an epoxy resin (A1) having a predetermined structure, and the curing agent (B) includes a phenol resin (B1) having a predetermined structure, wherein the content of a c=1 component included in the total amount of the phenol resin (B1) is not less than 40% in terms of area percentage and the content of a C≧4 component is not more than 20% in terms of area percentage, as measured by the area method of gel permeation chromatography. Also disclosed is a semiconductor device obtained by encapsulating a semiconductor element with a cured product of the resin composition for encapsulating a semiconductor.
US08653204B2	Carboxylic polybenzimidazole A carboxylic polybenzimidazole includes at least one of the following functional group of formula (I): wherein G is a group containing a carboxylic acid end group or a carboxylated end group.
US08653201B2	Ethylene polymer composition A composition suitable for use in pressure pipes and pipe fittings is disclosed comprising polymer of ethylene and from 0.5 to 5 wt % of a C4-C8 alpha-olefin which has a natural density of 935-956 kg/m3, a melt index MI5 of 0.15-0.5 g/10 min, a dynamic complex viscosity at 100 rad/s and 190° C. (η100) of no more than 2500 Pa·s, a relationship between η100 and dynamic complex viscosity measured in Pa·s at 0.01 rad/s and 190° C. (η0.01) defined by the equation η0.01>115000+30. η100, and an environmental stress crack resistance as measured by a notched pipe test performed according to ISO13479:1997 on 110 mm SDR 11 pipes at 80° C. and a pressure of 9.2 bar, of greater than 1000 hours, or: wherein the C4-C8 alpha-olefin is 1-hexene or 1-octene.
US08653199B2	Functionalized olefin polymers This invention relates to a composition comprising a functionalized C3 to C40 olefin polymer comprising at least 50 mol % of one or more C3 to C40 olefins, and where the olefin polymer, prior to functionalization, has: a Dot T-Peel of 1 Newton or more on Kraft paper; an Mw of 10,000 to 100,000; and a branching index (g′) of 0.98 or less measured at the Mz of the polymer when the polymer has an Mw of 10,000 to 60,000, or a branching index of 0.95 or less measured at the Mz of the polymer when the polymer has an Mw of 10,000 to 100,000; and where the C3 to C40 olefin polymer comprises at least 0.001 wt % of a functional group. This invention further relates to blends of such functionalized polymers with other polymers including non-functionalized C3 to C40 olefin polymers as described above.
US08653198B2	Method for the preparation of a heterophasic copolymer and uses thereof Methods for preparing an impact copolymer by selecting a continuous phase polymer having a first melt flow rate and selecting a rubber phase polymeric material such that the final melt flow rate of the impact copolymer is within 2 g/10 min of the first melt flow rate. Impact copolymers made from such methods and films and molded articles produced from such impact copolymers are also included.
US08653196B2	Method for preparing polyethylene with high melt strength The present invention is a method for increasing the melt strength of a polyethylene resin comprising reacting the polyethylene resin with an alkoxy amine derivative corresponding to the formula: (R1)(R2)N—O—R3 where R1 and R2 are each independently of one another, hydrogen, C4-C42 alkyl or C4-C42 aryl or substituted hydrocarbon groups comprising O and/or N, and where R1 and R2 may form a ring structure together; and where R3 is hydrogen, a hyrdrocarbon or a substituted hydrocarbon group comprising O and/or N. Preferred groups for R3 include —C1-C19alkyl; —C6-C10aryl; —C2-C19akenyl; —O—C1-C19alkyl; —O—C6-C10aryl; —NH—C1-C19alkyl; —NH—C6-C10aryl; —N—(C1-C19alkyl)2. R3 most preferably contains an acyl group.
US08653194B2	Quasi-melt processes for single polymer composites and products thereof Processes and compounds are described herein for single polymer composites based on a process for making the single polymer composites that includes the steps of heating a matrix material to create polymer melt, cooling the polymer melt to below its Tm to create an undercooled polymer melt, or quasi-melt, and combining the melt with an enhancing or reinforcing material to produce a single polymer composite. The process can produce materials that do not have any degradation of the polymer characteristic of the enhancing material due to melting of the polymer in the enhancing material.
US08653184B2	Plasticised polyvinyl chloride and processes for making the same Esters of cyclohexane polycarboxylic acids are used as plasticisers for polyvinyl chloride to enable products with comparable mechanical properties to be obtained using less polyvinyl chloride. Use of these esters also produces formulations with increased stability to ultra-violet light, improved low temperature properties, lower viscosity and improved processability as well as reduced smoke on burning. The esters of cyclohexane polycarboxylic acids may be used alone or in admixture with other plasticisers when the esters of cyclohexane polycarboxylic acids may act as viscosity depressants. Fast fusing plasticisers may also be included. The formulations and processes of making these formulations are particularly useful in the production of a range of goods from semi-rigid to highly flexible materials and are particularly useful in the production of medical materials, toys, and food contact articles.
US08653181B2	Polymer and use thereof The invention relates to new copolymers comprising a special phosphate functional monomer, and to uses thereof for example in coatings. The new copolymers can impart improved scrub resistance to said coatings.
US08653170B2	Dynamic vulcanization process for preparing thermoplastic elastomers Described in one aspect is a process for preparing a low durometer thermoplastic vulcanizate composition comprising melt blending one or more thermoplastic polymer(s) with a cross-linkable elastomer under conditions of dynamic vulcanization; adding at or after the start of the melt blending at least one curative agent for the elastomer so as to cross-link the elastomer during the melt blending; introducing process oil into the melt blending before, during and/or after the addition of the curative agent; and, extruding a fully crosslinked thermoplastic vulcanizate having a Shore A Hardness of less than 25.
US08653169B2	Propylene copolymers for adhesive applications Disclosed herein are adhesives comprising a copolymer comprising at least 80 wt % of units derived from propylene and from about 1 to about 20 wt % of units derived from at least one C6 to C10 alpha-olefin. The copolymer has a molecular weight of less than 100,000 and a heat of fusion between about 10 and about 70 J/g. An adhesive containing the copolymer preferably exhibits at least 50% fiber tear at −18° C. and at least 50% fiber tear at +25° C. using Inland paper board as a substrate; a viscosity of less than 50,000 mPa sec at 190° C., a set time of less than 4 seconds and a toughness of at least 3.4 megajoule/m3.
US08653168B2	Flame-retardant thermoplastic molding composition The invention relates to a thermoplastic molding composition comprising a) from 30 to 95% by weight of at least one aliphatic polyamide or copolyamide, as component A, b) from 1 to 15% by weight of at least one cyclic phenoxyphosphazene having at least 3 phenoxyphosphazene units, as component B, c) from 3 to 20% by weight of at least one (di)phosphinate salt, as component C, d) from 1 to 15% by weight of at least one reaction product of melamine with a phosphorus acid, as component D, e) from 0 to 5% by weight of at least one metal borate, as component E, f) from 0 to 20% by weight of at least one impact-modifying polymer, as component F, g) from 0 to 50% by weight of glass fibers, as component G, and h) from 0 to 30% by weight of further additives, as component H, where the total amount of components A to H gives 100% by weight.
US08653167B2	Molding composition for photovoltaic junction boxes and connectors A molding composition is disclosed which contains specific amounts of poly(arylene ether), styrenic polymer, hydrogenated block copolymer, flame retardant, and polytetrafluoroethylene. The molding composition performs well on a battery of tests, including heat resistance, impact strength, melt flow, and flame retardancy, and is particularly useful for producing photovoltaic junction boxes and connectors.
US08653161B2	Dispersant for hydraulically setting systems Polymers P as dispersants, in particular as liquefiers, for hydraulically setting systems, and hydraulically setting systems including the polymer P. The polymer P includes at least one acid unit, at least one ester unit, and at least one unit containing terephthalate or naphthalate.
US08653158B2	Lightweight wall repair compounds Herein are disclosed wall repair compounds comprising at least one or more polymeric binder latex emulsions, one or more inorganic fillers, and comprising an amount of organic polymeric thickener that is less than about 0.1 percent by weight based on the total weight of the wall repair compound. In certain embodiments, the wall repair compound comprises an inorganic filler system selected such that such that synthetic inorganic fillers comprise essentially 100 percent of the inorganic filler used. In certain embodiments, the wall repair compound comprises one or more glycol ether smoothing agents.
US08653157B2	Polyurethane compound and shoe soles made therefrom A polyurethane compound is disclosed, comprising the reaction product of an isocyanate and one or more polyols including at least one polytetramethylene ether glycol and polyethylene wax. The latter two ingredients greatly enhance abrasion resistance of the compound, making the compound particularly suitable for use as an outsole of footwear for rugged use applications.
US08653155B2	Polymers having lipophilic hydrocarbon and biodegradable polymeric segments The present invention pertains, among other things, to polymers having one or more lipophilic hydrocarbon segments and one or more biodegradable polymeric segments, to methods of making such polymers and to products formed using such polymers.
US08653147B2	Inorganic/organic dispersant and application thereof The present invention discloses an inorganic/organic mixed component (I/O) dispersant and applications thereof, which is primarily applied to dispersing nanoparticles of metal oxides. The I/O dispersant of the present invention can be a composite of inorganic clay and an organic surfactant, a composite of inorganic clay and polyoxyalkylene-amine, or a composite of inorganic clay, polyisobutylene succinic anhydride (PIB-SA) and hydrochloric acid salt or tetraalkyl quaternary salt of polyoxyalkylene-amine, or fatty amines. By mixing with the I/O dispersant of the present invention, nanoparticles of a metal oxide can be uniformly dispersed without aggregation particularly at high solid content. The dispersion has a lower viscosity and is relatively stable in storage even at high temperature.
US08653145B2	Method for alleviating climacteric symptoms The present invention is a method for alleviating at least one climacteric symptom in a climacteric subject using an anticholinergic agent. To illustrate the instant invention, homatropine was shown to relieve hot flushes in peri-menopausal and post-menopausal women.
US08653144B2	Treatment of pervasive developmental disorders with redox-active therapeutics Methods of treating or suppressing pervasive developmental disorders (PDDs) including; autistic disorder, Asperger's syndrome, childhood disintegrative disorder (CDD), Rett's disorder, and PDD-not otherwise specified (PDD-NOS) or attention deficit/hyperactivity disorder (ADHD) comprising administering to a subject in need thereof a therapeutically effective amount of one or more compounds as disclosed herein.
US08653131B2	Polymeric benzyl carbonate-derivatives The present invention relates to polymeric derivatives, which can be conjugated to an amino-containing drug to improve its in vivo properties. The polymeric derivative can subsequently be released to yield the drug in its native form. Methods of preparing and using these polymeric derivatives and drug conjugates are described.
US08653130B2	Compositions containing sesamin-class compound(s) and arachidonic acid class compound(s) A method by which the physiological activities of sesamin-class compounds can be efficiently exhibited and enhanced, as well as an effective compound that can be combined with the sesamin-class compounds to this end. By using sesamin-class compounds in combination with more than specified proportions of arachidonic acid class compounds, the physiological activities of the sesamin-class compounds, for example, their anti-fatigue action is synergistically enhanced to provide compositions that are safe in humans and non-human animals and which hence can be ingested continuously.
US08653128B1	Veterinary composition and method A stable liquid pharmaceutical formulation containing an N-phenylpyrazole derivative, a crystallization inhibitor/viscolizer and a solvent/co-solvent system comprised of a glycol ether solvent and at least one mono alkyl ester co-solvent; and the use of such a formulation for the prevention and/or treatment of infestations with fleas and ticks.
US08653123B2	Ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for treating retinal diseases The present invention relates to method of treating retinal diseases in a subject in need of such treatment, which comprises administering a therapeutically effective amount of a composition comprising a ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl) -2-methylphenyl]methanol, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
US08653119B2	Methods for treating transthyretin amyloid diseases Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods are disclosed.
US08653117B2	Composition comprising at least one oxazoline to inhibit migration of langerhans cells, and uses thereof The invention concerns a composition containing at least an oxazolin, optionally combined with at least a compound such as a metalloprotease inhibitor, a PKC inhibitor, an anti-inflammatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an alkanolamide, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such composition on the skin and/or mucosa.
US08653112B2	Substituted pyrazoles as estrogen receptor ligands The invention provides a compound of formula (I) wherein G is a pyrazole ring as defined in the specification and R4, R5, R6 and R7 are as defined in the specification; or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity.
US08653108B1	Oximes for treatment of peripheral and central nervous system exposure to acetyl cholinesterase inhibitors The present invention relates to non-charged oxime compounds which are acetyl cholinesterase (AChE) reactivators of inhibited AChE and which protect against organophosphate poisoning both peripherally and in the central nervous system. Also disclosed are pharmaceutical compositions and methods for preparing the reactivator compounds and associated intermediates.
US08653102B2	Substituted 2-oxo- and 2-thioxo-dihydroquinoline-3-carboxamides as KCNQ2/3 modulators The invention relates to substituted 2-oxo- and 2-thioxo-dihydroquinoline-3-carboxamides to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
US08653101B2	Substituted 2-oxy-quinoline-3-carboxamides as KCNQ2/3 modulators The invention relates to substituted 2-oxy-quinoline-3-carboxamides, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
US08653097B2	Tetra-aza-heterocycles as phosphatidylinositol-3-kinases (P13-kinases) inhibitor The present invention encompasses compounds of general formula (1) wherein R1 to R4, A, X, m and k are defined as in claim 1, which are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.
US08653096B2	Chemokine receptor antagonists and methods of use thereof Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: or physiologically acceptable salt thereof.
US08653085B2	Diketopiperazine salts for drug delivery and related methods Drug delivery systems have been developed based on the formation of diketopiperazine carboxylate salts and microparticles containing the same. The systems may further comprise a bioactive agent. Related methods for making and using the biologically active agent delivery compositions are also provided. In certain embodiments, the pharmaceutically acceptable salts described can be formed by removal of solvent by methods including distillation, evaporation, spray drying or lyophilization.
US08653079B2	Pyrazolo [4,3-C] cinnolin-3-one M1 receptor positive allosteric modulators The present invention is directed to pyrazolo[4,3-c]cinnolin-3-one compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.
US08653077B2	Inhibitors of human phosphatidylinositol 3-kinase delta Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation, in which PI3Kδ plays a role in leukocyte function are disclosed. Preferably, the methods employ active agents that selectively inhibit PI3Kδ, while not significantly inhibiting activity of other PI3K isoforms. Compounds are provided that inhibit PI3Kδ activity, including compounds that selectively inhibit PI3Kδ activity. Methods of using PI3Kδ inhibitory compounds to inhibit cancer cell growth or proliferation are also provided. Accordingly, the invention provides methods of using PI3Kδ inhibitory compounds to inhibit PI3Kδ-mediated processes in vitro and in vivo.
US08653074B2	Substituted sodium 1H-pyrazol-5-olate The present application relates to sodium 1-[6-(morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-olate, to processes for its preparation, to its use for the treatment and/or prophylaxis of diseases and to its use for the preparation of medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular and haematological diseases and kidney diseases, and for promoting wound healing.
US08653069B2	Aralkyl substituted piperidine or piperazine derivatives and their use for treating schizophrenia The present invention discloses an aralkyl substituted piperidine or piperazine derivative and the use of the derivative in preparation of medicaments for treating schizophrenia and correlative psychoneuroses. It is shown by pharmacological tests that the derivative of the present invention has better antischizophrenic effect and less toxicity. Said derivative is a free base or salt of the compound having the following general formula.
US08653065B1	Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder A pharmaceutical composition comprising a drug substance consisting essentially of a pharmaceutically acceptable organic acid addition salt of an amine containing pharmaceutically active compound wherein the amine containing pharmaceutical active compound is selected from the group consisting of racemic or single isomer ritalinic acid or phenethylamine derivatives and the drug substance has a physical form selected from amorphous and polymorphic.
US08653064B2	Crystalline forms of sodium 4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-D][2]benzazepin-2-yl]amino}-2-methoxybenzoate The present invention is directed to a compound of formula (I): or a crystalline form thereof, or a solvate thereof; to a solid pharmaceutical composition comprising a pharmaceutically effective amount of the compound of formula (I), or a crystalline form thereof, or a solvate thereof, and at least one pharmaceutically acceptable carrier or diluent, and to the use of a compound of formula (I), or a crystalline form thereof, or a solvate thereof, for treating a patient suffering from, or subject to, a disease, disorder, or condition mediated by Aurora kinase, and methods related thereto.
US08653059B2	Heterocyclic compounds as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes The present invention is directed to substituted six-membered heterocyclic compounds of structural formula (I) which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as obesity and diabetes, particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
US08653054B2	2-(N-substituted piperazinyl) steroid derivatives Novel chemical agents are described herein. More specifically, 2-(N-substituted piperazinyl) pregnane and 2-(N-substituted piperazinyl) androstane derivatives exhibiting cytotoxicity on a variety of cancer cell lines are disclosed herein.
US08653052B2	Drug combination and its use in the treatment of muscle loss The present invention is a product comprising a β2 agonist and a progestin, as a combined preparation for separate, simultaneous or sequential use in the treatment or prevention of muscle loss. The present invention is also a β2 agonist selected from R,R-formoterol, indacaterol or ritodrine, for use in the treatment or prevention of muscle loss.
US08653048B2	Prodrugs based on gemcitabine structure and synthetic methods and applications thereof Prodrugs based on gemcitabine structure shown in formula (I) as well as their synthetic method and application are disclosed in the present invention, wherein the definitions for the groups of a, b, c, d, E, Z and V are described in the specification. By modifying the N4 group, the solubility, the bioavailability and the organ specificity of the prodrugs are improved. Therefore, the fast metabolism problem is overcome for the produced prodrugs compounds. Intestinal toxicity induced by gemcitabine is decreased. Thereby, the prodrugs can be delivered by oral administration in clinics and further improve their anti-tumor, anti-cancer, anti-infection and diffusion preventing capability, and can also specifically act on liver or colon. The synthetic method is simple and adapted to industrial production.
US08653046B2	Controlling transgene expression across the skin The invention relates to the use of a skin permeating compound such as phloretin for controlling transgene expression under control of the Pseudomonas putida DOT-T1E-derived bacterial repressor TtgR, to a vector comprising the genetic code for the repressor TtgR fused to a transactivation or a transrepressor domain, to a vector comprising a TtgR-specific operator sequence (OTtgR), a promoter and a polynucleotide coding for an endogenous or exogenous protein, and to a mammalian cell transiently or constitutively transfected with the mentioned vectors, and to mammals comprising such cells in nano- or microcontainers.
US08653045B2	Induction of thyroid iodide-handling gene expression in human cancers Dual suppression of the MAP kinase and PI3K/Akt pathways showed synergistic or greatly enhanced anti-melanoma cell effects, compared to suppression of a single pathway, including the inhibition of cell proliferation, transformation and invasion, induction of G0/G1 cell cycle arrest and, importantly, cell apoptosis. Remarkably, suppression of either pathway induces the expression of thyroid iodide-handling genes and dual suppression of the two pathways synergistically and robustly induces expression of these genes, accompanied by uptake of radioiodine in the cells. These genes include sodium/iodide symporter, thyroid-stimulating hormone receptor, thyroglobulin, thyroperoxidase, pendrin gene, thyroid transcription factors (e.g., TTF-1, TTF-2, PAX8) and other thyroid genes. Targeting major signaling pathways, such as the MAP kinase and PI3K/Akt pathways, for potent cell death, optionally coupled with induction of thyroid gene expression for adjunct radioiodine ablation therapy may be used for many human cancers, both thyroid and non-thyroid.
US08653040B2	Compositions containing sesamin-class compound(s) and quercetin glycoside(s) The purpose of the present invention is to provide a means of enhancing the bodily absorption of sesamin-class compounds. By using sesamin-class compounds and quercetin glycosides in combination, the bodily absorption of the sesamin-class compounds can be enhanced.
US08653035B2	Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of glioblastoma (GBM) and other cancers The present invention relates to immunotherapeutic peptides and their use in immunotherapy, in particular the immunotherapy of cancer. The present invention discloses tumor-associated T-helper cell peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumor immune responses. In particular, the composition of the peptides of the present invention can be used in vaccine compositions for eliciting anti-tumor immune responses against gliomas.
US08653033B2	Method for administering omega-conopeptide The present invention is directed to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, an antioxidant, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil.
US08653027B2	Method of treatment of type-1 diabetes with humanin analogues The present invention is based on the discovery that Humanin and humanin analogues protect pancreatic beta cells in vitro and in vivo from apoptosis. Accordingly, humanin and its analogues are useful for preventing and treating diabetes and promoting beta cell survival in a number of applications.
US08653025B2	Polyheterocyclic compounds highly potent as HCV inhibitors The present invention discloses the structure, preparation methods and uses of a series of novel polyheterocyclic based compounds (Ia-Ib and IIa-IIb) that are highly effective for inhibiting hepatitis C virus (HCV): where the structural variables are defined herein. The present invention is also provides a method of treating HCV infection by the polyheterocyclic based HCV inhibitory compounds, compositions and therapeutic methods.
US08653019B2	Stain remover containing fluoropolymer A stain remover which comprises a copolymer made from as essential ingredients (a) a polymerizable monomer having a polyfluoroalkyl group with less than 8 carbon atoms and represented by the general formula H2C═CXCOO—Y—Rf and (b) a fluorine-free polymerizable monomer represented by the following general formula: H2C═CXCOO—(RO)n—X. The stain remover is effective in minimizing the amount of an organic solvent to be used. It imparts to a substrate the excellent property of removing stains therefrom and a satisfactory texture.
US08653016B2	Biodegradable cleaning composition The present invention provides a biodegradable cleaning composition that includes a surfactant component including an ethoxylated 2-propyl heptanol, a chelating component including a tri-sodium salt of methylglycinediacetic acid and an emulsifier component including an ethoxylated hexanol having the formula C6H13O(CH2CH2O)H. The ethoxylated 2-propyl heptanol has the formula C5H11CH(C3H7)CH2O(C2H4O)pH, wherein p is a number of from 3 to 6. The composition also includes water and an acid component to establish a pH of the composition at less than 2. The composition is substantially free of solvents thereby reducing emission of volatile organic compounds and reducing potential environmental pollution and health hazards. The composition is also effective in removing rust, lime soap, and metal salts of fatty acids from hard surfaces including metal, vinyl, and fiberglass.
US08653010B2	Methods of using reactive surfactants in subterranean operations Novel uses of reactive surfactants in treating subterranean formations and/or proppant particulates are provided. In one embodiment, the present invention provides a surfactant-treated proppant particulate comprising a proppant particulate that comprises at least one surface that has been allowed to interact with a reactive surfactant.
US08653007B2	Compositions, methods and related uses for cleaving modified DNA Compositions, methods and related uses are provided relating to cleaving modified DNA. For example, a set of DNA fragments obtainable by enzymatic cleavage of a large DNA is described where at least 50% are similarly sized and have a centrally positioned modified nucleotide. In addition, an enzyme preparation is provided that includes one or more enzymes that recognize a modified nucleotide in a DNA and cleave the DNA at a site that is at a non-random distance from the modified nucleotide. The one or more enzymes are further characterized by an N-terminal conserved domain with greater than 90% amino acid sequence homology to WXD(X)10YXGD. The related uses include creating a methylome, methods of purifying DNA fragments containing a modified nucleotide and diagnostic applications.
US08653006B2	Metabolite biomarkers for the detection of esophageal cancer using NMR Methods for the detection and screening of esophageal adenocarcinoma (EAC) patients and for the monitoring of EAC treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. In other aspects, methods for detection and screening for the progression of high-risk conditions (BE and HGD) to EAC and to monitoring treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. The biomarkers are sensitive and specific for the detection of EAC, and can also be used to classify Barrett's esophagus (BE) and high-grade dysplasia (HGD), which are widely regarded as precursors of EAC.
US08653005B2	Fluorinated precursors of superconducting ceramics, and methods of making the same This invention provides a method of making a fluorinated precursor of a superconducting ceramic. The method comprises providing a solution comprising a rare earth salt, an alkaline earth metal salt and a copper salt; spraying the solution onto a substrate to provide a film-covered substrate; and heating the film-covered substrate in an atmosphere containing fluorinated gas to provide the fluorinated precursor.
US08653004B2	Actives-comprising polymer networks, processes for producing them, and their use Process for producing actives-comprising polymeric networks from oligomers containing (meth)acrylate groups, optionally from further monomers, and from actives, the polymeric networks obtainable by the process, and the use of the networks for various purposes, more particularly for protecting materials or in crop protection.
US08653002B2	Aqueous suspension concentrate formulations containing saflufenacil The present invention relates to aqueous suspension concentrate formulation for plant protection comprising: 2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1-(2H)pyrimidinyl]-4-fluoro-N-[[methyl(1-methylethyl)amino]sulfonyl]benzamide in the form of its crystalline anhydrate; at least one non-ionic surfactant selected from polyoxyethylene-polyoxy-C3-C4-alkylene block copolymers; at least one anionic surfactant comprising at least one arylsulfonate group; and water; wherein the pH value of the formulation is in the range of 3 to 7.
US08652997B2	Active compound combinations The invention relates to active compound combinations, in particular a fungicidal and/or insecticidal composition, comprising Isotianil (3,4-dichloro-N-(2-cyanophenyl)-5-isothiazolecarboxamide) and at least one further insecticide of the tetronic acid derivatives group and optionally one further insecticide of the neonicotinoids.Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi and/or microorganisms and/or pests of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed.
US08652995B2	Steam activated non-lignocellulosic based carbons for ultracapacitors A method for producing an activated carbon material includes heating a non-lignocellulosic carbon precursor to form a carbon material and reacting the carbon material with steam to form an activated carbon material. The activated carbon material is suitable to form improved carbon-based electrodes for use in high energy density devices.
US08652987B2	Method for producing alloy catalyst for redox reaction A method for producing an alloy catalyst for redox reaction comprising alloy particles of platinum and nickel, wherein the alloy particles are equipped at an outer surface with a crystal lattice plane represented by a Miller index {111} and have an average particle diameter in a range of 6 to 20 nm, the method comprising: dissolving, in an alcohol, a salt and/or complex of platinum, a salt and/or complex of nickel, and a polymer containing a plurality of salt structures comprising an organic cation and a halogen anion in a polymer chain and heating the resulting solution to reflux under an inert atmosphere.
US08652986B2	Ziegler-Natta catalyst for olefin polymerization The present invention relates to a Ziegler-Natta catalyst, and more specifically to a Ziegler-Natta catalyst for olefin polymerization which may use a compound of Formula 3 as an internal electron donor to obtain polymers with high activity, wide molecular weight distribution and low content of fine particle.
US08652977B2	Heat-resistant nonwoven fabric The present invention provides a heat-resistant nonwoven fabric wherein the nonwoven fabric is formed from a poly(phenylene sulfide) fiber, and 30% by weight or more of the poly(phenylene sulfide) fiber has a crystallinity of 25 to 50%. Moreover, the properties of the heat-resistant nonwoven fabric can be further improved by making the nonwoven fabric have a multilayer structure in which layers composed of a poly(phenylene sulfide) filamentary fiber and layers composed of a poly(phenylene sulfide) fine fiber are stacked and integrated.
US08652976B2	Fixable nonwoven interlining material used in the textile industry The invention relates to a fixable nonwoven interlining material for use in the textile industry, comprising at least one melt-spun fiber layer and at least one additional fibrous material layer, the fixable interlining material being provided with an adhesive substance at least in partial regions. A particularly high elasticity of the fixable interlining material is achieved by the fact that the melt-spun fibers are composed of an elastic fibrous material, and the at least one layer of fibrous material is composed of staple fibers, and the at least one elastic melt-spun fiber layer and the at least one staple fiber layer are laid one on top of the other in the form of a flat unbonded fiber fabric, and are subsequently bonded by use of a bonding step known as such.
US08652975B1	Flame resistant fabric The invention provides a flame resistant woven fabric comprising a plurality of first yarns and a plurality of second yarns, wherein the first yarns are disposed in a first direction in the woven fabric, the second yarns are disposed in a second direction in the woven fabric, and the second direction is substantially perpendicular to the first direction. The invention further provides a process for producing a flame resistant woven fabric.
US08652974B2	Method and system for pre-heating of semiconductor material for laser annealing and gas immersion laser doping A fiber laser system enables a method for treating a semiconductor material by preheating a wafer for laser annealing and gas immersion laser doping by a laser source. A long wave length fiber laser having a Gaussian or similar profile is applied in a full-width ribbon beam across an incident wafer. Preferably the wavelength is greater than 1 μm (micron) and preferably a Yb doped fiber laser is used. The process is performed in a suitable environment which may include doping species. The process ensures the temperature gradient arising during processing does not exceed a value that results in fracture of the wafer while also reducing the amount of laser radiation required to achieve controlled surface melting, recrystallization and cooling.
US08652971B2	Cavity process etch undercut monitor A MEMS device having a device cavity in a substrate has a cavity etch monitor proximate to the device cavity. An overlying layer including dielectric material is formed over the substrate. A monitor scale is formed in or on the overlying layer. Access holes are etched through the overlying layer and a cavity etch process forms the device cavity and a monitor cavity. The monitor scale is located over a lateral edge of the monitor cavity. The cavity etch monitor includes the monitor scale and monitor cavity, which allows visual measurement of a lateral width of the monitor cavity; the lateral dimensions of the monitor cavity being related to lateral dimensions of the device cavity.
US08652969B2	High aspect ratio and reduced undercut trench etch process for a semiconductor substrate A hydrofluorocarbon gas is employed as a polymer deposition gas in an anisotropic etch process employing an alternation of an etchant gas and the polymer deposition gas to etch a deep trench in a semiconductor substrate. The hydrofluorocarbon gas can generate a thick carbon-rich and hydrogen-containing polymer on sidewalls of a trench at a thickness on par with the thickness of the polymer on a top surface of the semiconductor substrate. The thick carbon-rich and hydrogen-containing polymer protects sidewalls of a trench, thereby minimizing an undercut below a hard mask without degradation of the overall rate. In some embodiments, an improvement in the overall etch rate can be achieved.
US08652966B2	Semiconductor device manufacturing method and semiconductor device A semiconductor manufacturing method includes: forming a seed film including a first metal over a bottom surface and a side wall of an opening portion formed over interlayer insulating films and a field portion located over the interlayer insulating film except the opening portion, forming a resist over the seed film and filling the opening portion with the resist, removing part of the resist, exposing the seed film formed over the upper portion of the side walls of the opening portion and the field portion, forming a cover film including a second metal, whose resistivity is higher than that of the first metal, over the seed film located over the upper portion of the side wall of the opening portion and the field portion, exposing the seed film by removing the resist, and forming a plating film including the first metal over the exposed seed film.
US08652961B1	Methods and structure for adapting MEMS structures to form electrical interconnections for integrated circuits Methods and structure for adapting MEMS structures to form electrical interconnections for integrated circuits. A first portion and a second portion of the metal conductor, which can be electrically isolated within a CMOS IC device, can be etched to form an unetched portion of the metal conductor. The MEMS device can be patterned, from a MEMS layer formed overlying the metal conductor, via a plasma etching process, during which the unetched portion of the metal conductor is protected from the plasma. The metal conductor can be electrically coupled to the CMOS IC device via a conductive jumper or the like. Furthermore, the integrated CMOS-MEMS device can include a MEMS device coupled to a CMOS IC device via an electrically isolated metal conductor within the CMOS IC device. Also, the metal conductor can be electrically coupled to the substrate of the CMOS IC device via a conductive jumper.
US08652960B2	Active area bonding compatible high current structures A semiconductor structure comprises a top metal layer, a bond pad formed on the top metal layer, a conductor formed below the top metal layer, and an insulation layer separating the conductor from the top metal layer. The top metal layer includes a sub-layer of relatively stiff material compared to the remaining portion of the top metal layer. The sub-layer of relatively stiff material is configured to distribute stresses over the insulation layer to reduce cracking in the insulation layer.
US08652958B2	Vertical deep ultraviolet light emitting diodes A vertical geometry light emitting diode with a strain relieved superlattice layer on a substrate comprising doped AlXInYGa1-X-YN. A first doped layer is on the strain relieved superlattice layer AlXInYGa1-X-YN and the first doped layer has a first conductivity. A multilayer quantum well is on the first doped layer comprising alternating layers quantum wells and barrier layers. The multilayer quantum well terminates with a barrier layer on each side thereof. A second doped layer is on the quantum well wherein the second doped layer comprises AlXInYGa1-X-YN and said second doped layer has a different conductivity than said first doped layer. A contact layer is on the third doped layer and the contact layer has a different conductivity than the third doped layer. A metallic contact is in a vertical geometry orientation.
US08652957B2	High-K gate dielectric oxide A dielectric such as a gate oxide and method of fabricating a gate oxide that produces a more reliable and thinner equivalent oxide thickness than conventional SiO2 gate oxides are provided. Gate oxides formed from elements such as zirconium are thermodynamically stable such that the gate oxides formed will have minimal reactions with a silicon substrate or other structures during any later high temperature processing stages. The process shown is performed at lower temperatures than the prior art, which further inhibits reactions with the silicon substrate or other structures. Using a thermal evaporation technique to deposit the layer to be oxidized, the underlying substrate surface smoothness is preserved, thus providing improved and more consistent electrical properties in the resulting gate oxide.
US08652955B2	Manufacturing method of semiconductor integrated circuit device Provided is a manufacturing method of semiconductor integrated circuit, which is effective when applied to a processing technique for a gate electrode or the like. In the patterning of a gate stack film having a high-k gate insulating film and a metal electrode film in a memory region, etching for a cut region between adjacent gate electrodes is performed first using a first resist film and, after the first resist film that is no longer needed is removed, etching for a line and space pattern is performed using a second resist film.
US08652953B2	Plasma doping method with gate shutter In a plasma doping device according to the invention, a vacuum chamber is evacuated with a turbo-molecular pump as an exhaust device via a exhaust port while a predetermined gas is being introduced from a gas supply device in order to maintain the inside of the vacuum chamber to a predetermined pressure with a pressure regulating valve. A high-frequency power of 13.56 MHz is supplied by a high-frequency power source to a coil provided in the vicinity of a dielectric window opposed to a sample electrode to generate inductive-coupling plasma in the vacuum chamber. A high-frequency power source for supplying a high-frequency power to the sample electrode is provided. Uniformity of processing is enhanced by driving a gate shutter and covering a through gate.
US08652952B2	Semiconductor structure made using improved multiple ion implantation process Methods and apparatus provide for: a first source of plasma, wherein the plasma includes a first species of ions; a second source of plasma, wherein the plasma includes a second species of ions; selection of the plasma from the first and second sources; and acceleration the first species of ions or the second species of ions toward a semiconductor wafer.
US08652949B2	Method of manufacturing semiconductor wafer A method of manufacturing a semiconductor wafer, which includes: a semiconductor substrate made of silicon and having both a central area and an outer periphery area; and a compound semiconductor layer made of a nitride-based semiconductor and formed on the semiconductor substrate, the method comprising: forming a growth inhibition layer to inhibit the compound semiconductor layer from growing on a tapered part provided in the outer periphery area of the semiconductor substrate; and growing the compound semiconductor layer on at least the central area of the semiconductor substrate, after the growth inhibition layer has been formed.
US08652945B2	Epitaxy of high tensile silicon alloy for tensile strain applications Embodiments of the present invention generally relate to methods for forming silicon epitaxial layers on semiconductor devices. The methods include forming a silicon epitaxial layer on a substrate at increased pressure and reduced temperature. The silicon epitaxial layer has a phosphorus concentration of about 1×1021 atoms per cubic centimeter or greater, and is formed without the addition of carbon. A phosphorus concentration of about 1×1021 atoms per cubic centimeter or greater increases the tensile strain of the deposited layer, and thus, improves channel mobility. Since the epitaxial layer is substantially free of carbon, the epitaxial layer does not suffer from film formation and quality issues commonly associated with carbon-containing epitaxial layers.
US08652940B2	Wafer dicing used hybrid multi-step laser scribing process with plasma etch Methods of dicing semiconductor wafers, each wafer having a plurality of integrated circuits, are described. A method includes forming a mask above the semiconductor wafer. The mask is composed of a layer covering and protecting the integrated circuits. The mask is patterned with a multi-step laser scribing process to provide a patterned mask with gaps. The patterning exposes regions of the semiconductor wafer between the integrated circuits. The semiconductor wafer is then etched through the gaps in the patterned mask to singulate the integrated circuits.
US08652939B2	Method and apparatus for die assembly Methods and apparatus for die assembly. A method includes forming a trench extending from an active surface of a semiconductor substrate comprising a plurality of integrated circuit dies having connector terminals extending from the active surface, the trench extending into, but not through, the semiconductor substrate; forming a protective layer overlying the active surface of the semiconductor substrate and the trench, and covering the lower portion of the connector terminals; opening a pre-dicing opening in the protective layer and within the trench; applying a tape over the active surface of the semiconductor wafer, the protective layer and the connector terminals; and performing an operation on a backside of the semiconductor substrate to remove material until the pre-dicing opening is exposed on the backside of the semiconductor wafer. An apparatus includes a semiconductor substrate with integrated circuits and a protective layer surrounding connector terminals of integrated circuits.
US08652938B2	Thermally releasable sheet-integrated film for semiconductor back surface, method of collecting semiconductor element, and method of producing semiconductor device The present invention relates to a thermally releasable sheet-integrated film for semiconductor back surface, which includes: a pressure-sensitive adhesive sheet including a base material layer and a pressure-sensitive adhesive layer, and a film for semiconductor back surface formed on the pressure-sensitive adhesive layer of the pressure-sensitive adhesive sheet, in which the pressure-sensitive adhesive sheet is a thermally releasable pressure-sensitive adhesive sheet whose peel force from the film for semiconductor back surface decreases upon heating.
US08652934B1	Semiconductor substrate for photonic and electronic structures and method of manufacture A method of forming a substrate with isolation areas suitable for integration of electronic and photonic devices is provided. A common reticle and photolithographic technique is used to fabricate a mask defining openings for etching first and second areas in a substrate, with the openings for the second trench isolation areas being wider than the openings for the first trench isolation areas. The first and second trench isolation areas are etched in the substrate through the mask and filled with an oxide material. The oxide material is removed from the bottom of the second trench isolation areas. The second trench isolation areas are further etched to the deeper than the first trench isolation areas, and are then filled with oxide material. Electrical devices can be formed on the substrate and electrically isolated by the first trench isolation areas and photonic devices can be formed over the second trench isolation areas and be optically isolated from the substrate.
US08652930B2	Semiconductor device with self-biased isolation A method of fabricating a reduced surface field (RESURF) transistor includes forming a first well in a substrate, the first well having a first conductivity type, doping a RESURF region of the first well to have a second conductivity type, doping a portion of the first well to form a drain region of the RESURF transistor, the drain region having the first conductivity type, and forming a second well in the substrate, the second well having the second conductivity type. A plug region is formed in the substrate, the plug region extending to the RESURF region.
US08652927B2	Integration of non-noble DRAM electrode A method for forming a capacitor stack is described. In some embodiments of the present invention, a first electrode structure is comprised of multiple materials. A first material is formed above the substrate. A portion of the first material is etched. A second material is formed above the first material. A portion of the second material is etched. Optionally, the first electrode structure receives an anneal treatment. A dielectric material is formed above the first electrode structure. Optionally, the dielectric material receives an anneal treatment. A second electrode material is formed above the dielectric material. Typically, the capacitor stack receives an anneal treatment.
US08652926B1	Methods of forming capacitors A method of forming capacitors includes providing first capacitor electrodes within support material. The first capacitor electrodes contain TiN and the support material contains polysilicon. The polysilicon-containing support material is dry isotropically etched selectively relative to the TiN-containing first capacitor electrodes using a sulfur and fluorine-containing etching chemistry. A capacitor dielectric is formed over sidewalls of the first capacitor electrodes and a second capacitor electrode is formed over the capacitor dielectric. Additional methods are disclosed.
US08652922B2	Compact thermally controlled thin film resistors utilizing substrate contacts and methods of manufacture A method of forming a semiconductor structure includes forming a resistor on an insulator layer over a substrate and forming a trench in the resistor and into the substrate. The method also includes forming a liner on sidewalls of the trench and forming a core comprising a high thermal conductivity material in the trench and on the liner.
US08652915B2	Methods of fabricating semiconductor devices using preliminary trenches with epitaxial growth A method of fabricating a semiconductor device can be provided by etching sidewalls of a preliminary trench in a substrate that are between immediately adjacent gate electrode structures, to recess the sidewalls further beneath the gate electrode structures to provide recessed sidewalls. Then, the recessed sidewalls and a bottom of the preliminary trench can be etched using crystallographic anisotropic etching to form a hexagonally shaped trench in the substrate.
US08652914B2	Two-step silicide formation An aspect of the invention includes a method for forming a semiconductor device with a two-step silicide formation. First, a silicide intermix layer is formed over a source/drain region and a portion of an adjacent extension region. Any spacers removed to accomplish this may be replaced. Dielectric material covers the silicide intermix layer over the source/drain region. A contact opening for a via is etched into the dielectric material. A second silicide contact is formed on the silicide intermix layer, or may be formed within the source/drain region as long as the second silicide contact still contacts the silicide intermix layer.
US08652912B2	Methods of fabricating a transistor gate including cobalt silicide A method for fabricating a transistor gate with a conductive element that includes cobalt silicide includes use of a sacrificial material as a place-holder between sidewall spacers of the transistor gate until after high temperature processes, such as the fabrication of raised source and drain regions, have been completed. In addition, semiconductor devices (e.g., DRAM devices and NAND flash memory devices) with transistor gates that include cobalt silicide in their conductive elements are also disclosed, as are transistors with raised source and drain regions and cobalt silicide in the transistor gates thereof. Intermediate semiconductor device structures that include transistor gates with sacrificial material or a gap between upper portions of sidewall spacers are also disclosed.
US08652904B2	Semiconductor device with gate trench A method of manufacturing a semiconductor device is presented. The device has: a gate terminal formed from polysilicon and covered by an insulation layer; and a plug extending through an insulation layer to provide an electrical connection to the gate trench. A metal layer is deposited to cover at least a portion of the insulation layer. The metal layer is then etched to remove the metal layer from above the plug.
US08652903B2	Access transistor for memory device An access transistor for a resistance variable memory element and methods of forming the same are provided. The access transistor has first and second source/drain regions and a channel region vertically stacked over the substrate. The access transistor is associated with at least one resistance variable memory element.
US08652902B2	Floating gate semiconductor memory device and method for producing such a device Disclosed are methods for manufacturing a floating gate memory device and the floating gate memory device thus obtained. In one embodiment, a method is disclosed that includes providing a semiconductor-on-insulator substrate, forming at least two trenches in the semiconductor-on-insulator substrate, and, as a result of forming the at least two trenches, forming at least one elevated structure. The method further includes forming isolation regions at a bottom of the at least two trenches by partially filling the at least two trenches, thermally oxidizing sidewall surfaces of at least a top portion of the at least one elevated structure, thereby providing a gate dielectric layer on at least the exposed sidewall surfaces; and forming a conductive layer over the at least one elevated structure, the gate dielectric layer, and the isolation regions to form at least one floating gate semiconductor memory device.
US08652899B2	Method of fabricating pixel structure The present invention provides a pixel structure including a substrate, a patterned electrode disposed on the substrate, a first insulating layer disposed on the patterned electrode, a common electrode disposed on the first insulating layer, a second insulating layer disposed on the common electrode, and a drain disposed on the second insulating layer. The first insulating layer has a first through hole, and the second insulating layer has a second through hole. The drain includes a first portion electrically connected to the patterned electrode via the first through hole and the second through hole, and a second portion extending onto the common electrode. The common electrode is coupled with the patterned electrode to form a first storage capacitor and is coupled with the second portion to form a second storage capacitor.
US08652893B2	Semiconductor device and manufacturing method thereof A semiconductor device and its manufacturing method, wherein the NMOS device is covered by a layer of silicon nitride film having a high ultraviolet light absorption coefficient through PECVD, said silicon nitride film can well absorb ultraviolet light when being subject to the stimulated laser surface anneal so as to achieve a good dehydrogenization effect, and after dehydrogenization, the silicon nitride film will have a high tensile stress; since the silicon nitride film has a high ultraviolet light absorption coefficient, there is no need to heat the substrate, thus avoiding the adverse influences to the device caused by heating the substrate to dehydrogenize, and maintaining the heat budget brought about by the PECVD process.
US08652891B1	Semiconductor device and method of manufacturing the same The present invention discloses a semiconductor device, comprising a plurality of fins located on a substrate and extending along a first direction; a plurality of gate stack structures extending along a second direction and across each of the fins; a plurality of stress layers located in the fins on both sides of the gate stack structures and having a plurality of source and drain regions therein; a plurality of channel regions located between the plurality of source and drain regions along a first direction; characterized in that the plurality of gate stack structures enclose the plurality of channel regions. In accordance with the semiconductor device and the method of manufacturing the same of the present invention, an all-around nanowire metal multi-gate is formed in self-alignment by punching through and etching the fins at which the channel regions are located using a combination of the hard mask and the dummy gate, thus the device performance is enhanced.
US08652887B2	Multi-layer structures and process for fabricating semiconductor devices The present invention relates to a method for providing a Silicon-On-Insulator (SOI) stack that includes a substrate layer, a first oxide layer on the substrate layer and a silicon layer on the first oxide layer (BOX layer). The method includes providing at least one first region of the SOI stack wherein the silicon layer is thinned by thermally oxidizing a part of the silicon layer and providing at least one second region of the SOI stack wherein the first oxide layer (BOX layer) is thinned by annealing.
US08652874B2	Large scale patterned growth of aligned one-dimensional nanostructures A method of making nanostructures using a self-assembled monolayer of organic spheres is disclosed. The nanostructures include bowl-shaped structures and patterned elongated nanostructures. A bowl-shaped nanostructure with a nanorod grown from a conductive substrate through the bowl-shaped nanostructure may be configured as a field emitter or a vertical field effect transistor. A method of separating nanoparticles of a desired size employs an array of bowl-shaped structures.
US08652866B2	Sensor device and method A sensor device and method. One embodiment provides a first semiconductor chip having a sensing region. A porous structure element is attached to the first semiconductor chip. A first region of the porous structure element faces the sensing region of the first semiconductor chip. An encapsulation material partially encapsulates the first semiconductor chip and the porous structure element.
US08652863B2	Method of manufacturing an optical matrix device According to the method of manufacturing an optical matrix device of this invention, semiconductor films and gate insulating films which influence the characteristics of thin-film transistors most are formed in a vacuum (S12, S13), whereby the interfaces between the semiconductor films and gate insulating films are not contaminated. The semiconductor films and gate insulating films are formed in a vacuum, but wires need not be formed in a vacuum (S03). Thus, the semiconductor films and gate insulating films formed in a vacuum are transferred onto the wires formed beforehand (S21). Even if a substrate has a large area, the wires, semiconductor films and gate insulating films of the thin-film transistors can be formed efficiently.
US08652862B2	Method for etching insulating film and method for manufacturing semiconductor optical device A method for etching an insulating film includes the steps of forming an insulating film; forming a first resin layer composed of a non-silicon-containing resin on the insulating film; forming a pattern including projections and recesses in the first resin layer; forming a second resin layer composed of a silicon-containing resin to cover the projections and the recesses of the pattern in the first resin layer; etching the second resin layer by reactive ion etching with etching gas containing CF4 gas and oxygen gas until the projections of the first resin layer are exposed, a Si component of the second resin layer being oxidized in etching the second resin layer; selectively etching the first resin layer until the insulating film is exposed using as a mask the second resin layer buried in the recesses of the first resin layer to form a resin layer mask; and etching the insulating film using the resin layer mask. Further, in the step of etching the second resin layer, the reactive ion etching is performed under applying a self-bias voltage so that a Si product is removed, the Si product being provided from the Si component remaining in the second resin layer without being oxidized.
US08652859B2	Method for manufacturing light-emitting device and manufacturing apparatus of light-emitting device An object is to provide a method for manufacturing a light-emitting device in which a defective portion is insulated. In addition, another object is to provide a manufacturing apparatus of a light-emitting device in which a defective portion is insulated. After a hemispherical lens is formed to overlap with a light-emitting element, the defective portion is detected. Then, the hemispherical lens overlapping with the light-emitting element including the detected defective portion may be irradiated with a laser beam having a low energy density, and the defective portion may be insulated by light condensed through the hemispherical lens.
US08652858B2	Chip testing method A chip testing method includes cutting a wafer into chip packages, re-arranging the chip packages on a chip tray, and testing the re-arranged chip packages. The wafer includes a plurality of substrates vertically stacked thereon, and each of the plurality of substrates has a plurality of chips mounted thereon.
US08652857B2	Test apparatus, test method and manufacturing method for testing a device under test packaged in a test package Provided is a test apparatus for testing a device under test, including a dicing section that dices a wafer on which a plurality of devices under test are formed to separate each of the devices under test, a test packaging section that packages each of the devices under test resulting from the dicing by the dicing section in an individual test package, a testing section that tests the devices under test packaged in the test packages, a removing section that removes the devices under test that have been tested from the test packages, and a commercial packaging section that packages the devices under test removed from the test packages in commercial packages.
US08652852B2	Method of pumping fluid through a microfluidic device A method is provided for pumping fluid through a channel of a microfluidic device. The channel has an input port and an output port. The channel is filled with fluid and a pressure gradient is generated between the fluid at the input port and the fluid at the output port. As a result, fluid flows through the channel towards the output port.
US08652844B2	Methods for the cryopreservation of animal cells that contain high levels of intracellular lipids A method for cryopreservation of animal cells with high level of intracellular lipid content, comprises the steps of conducting a delipation procedure using one or more lipolytic agent(s) and/or lipogenesis inhibitors during culture of the animal cells to stimulate the hydrolysis of intracellular lipids to reduce the lipid content, and vitrifying the treated animal cells using a modified vitrification solution and a modified warming solution.
US08652840B2	Method for obtaining female germline stem cells and uses thereof The present invention relates to female germline stem cells and their progenitors, methods of isolation thereof, and methods of use thereof.
US08652839B2	HM1.24—utilizing cancer vaccines A cancer vaccine containing as an active ingredient an antigen-specific dendritic cell pulsed by an HM1.24 protein, HM1.24 peptide or transduced with an HM1.24-encoding gene, or HM1.24 protein-encoding DNA or RNA.
US08652837B2	Method and means for producing high titer, safe, recombinant lentivirus vectors Lentiviral vectors modified at the 5′ LTR or both the 5′ and 3′ LTR are useful in the production of recombinant lentivirus vectors (See the Figure). Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene enhances virus production. The vectors can contain inducible or conditional promoters.
US08652833B2	Cell culture container and method of producing the same To provide a cell culture chamber capable of reproducing a cell function in vivo, and a method of producing the same. The cell culture chamber according to the present invention has a concave-convex pattern formed on the surface on which cells are cultured. A concave portion of the concave-convex pattern includes cell culture portions and micro flow channels communicating with the cell culture portions. The bottom surface of each of the cell culture portions has a width 1.0 to 20 times an equivalent diameter of each of the cultured cells. A cell adhesion-inducing substance is formed only on the bottom surface and the side walls of the concave portion.
US08652831B2	Method and apparatus for analyte measurement test time A disposable biosensor test strip is provided that includes a plurality of penetrating members. Each penetrating member is associated with a capillary chamber that has a depth suitable for capillary flow of blood and holds a volume of less than about 1.0 .μl of the blood sample. A working electrode and a counter or reference electrode are disposed within the capillary chamber. A reagent is proximal to or in contact with at least the working electrode. The reagent includes an enzyme and a mediator. The reagent reacts with glucose to produce an electroactive reaction product. A blood sample, containing glucose, is applied into the capillary chamber. The capillary chamber directs capillary flow of the blood sample into contact with the reagent to cause the blood sample to at least partially solubilize or hydrate the reagent. The blood sample is detected in the capillary chamber. The electroactive reaction product is electro-oxidized or electro-reduced at the working electrode. Within 10 seconds after detecting, a determination is made of glucose concentration and a readout of the measurement is provided. The glucose determination is made by correlating the electro-oxidized or electro-reduced electroactive reaction product to the concentration of glucose in the blood sample.
US08652828B2	Nanochannel arrays and their preparation and use for high throughput macromolecular analysis Nanochannel arrays that enable high-throughput macromolecular analysis are disclosed. Also disclosed are methods of preparing nanochannel arrays and nanofluidic chips. Methods of analyzing macromolecules, such as entire strands of genomic DNA, are also disclosed, as well as systems for carrying out these methods.
US08652825B2	Microbial production of pyruvate and other metabolites Microbial production of pyruvate and metabolites derived from pyruvate in cells exhibiting reduced pyruvate dehydrogenase activity compared to wild-type cells. Acetate and glucose are supplied as a carbon sources.
US08652823B2	Strain for butanol production with increased membrane unsaturated trans fatty acids Bacteria that are not natural butanol producers were found to have increased tolerance to butanol when the membrane content of unsaturated trans fatty acids was increased. Feeding cells with unsaturated trans fatty acids increased their concentration in the membrane, which may also be accomplished by expressing a fatty acid cistrans isomerase.
US08652820B2	Thermotolerant Non-K12 Escherichia coli phytase and its production This invention relates to cloning and sequencing of thermotolerant phytase gene from Non-K12 Escherichia coli strain, ATCC 9637, phytase gene expression in Escherichia coli expression system, codon usage optimized and expression in Pichia pastoris, Pichia methanolica and Kluyeromyces lactis. The high level yield and thermotolerant enzyme was produced from fermentation of Pichia pastoris with optimized codon of phytase gene.
US08652819B2	Paenibacillus spp. and methods for fermentation of lignocellulosic materials Provided herein are methods for producing a fermentation product, such as ethanol, by co-culture of a member of the genus Paenibacillus and an ethanologenic microbe, such as yeast or E. coli. Also provided are methods for making enzymes useful in the saccharification of a pretreated lignocellulosic material. The enzymes may be made by culturing a member of the genus Paenibacillus in a composition suitable for production of such enzymes. An example of such a composition is a pretreated lignocellulosic material, for example, spent hydrolysates. Also provided are genetically modified members of the genus Paenibacillus that have been genetically modified to not produce an antimicrobial, for instance, a polymyxin E.
US08652816B2	Compositions and methods for 3-hydroxypropionate bio-production from biomass Methods of obtaining mutant nucleic acid sequences that demonstrate elevated oxaloacetate α-decarboxylase activity are provided. Compositions, such as genetically modified microorganisms that comprise such mutant nucleic acid sequences, are described, as are methods to obtain the same.
US08652815B2	Transformant comprising gene coding for ws/dgat and method of producing fatty acid ethyl esters using the same The present invention relates to a transformant comprising a gene encoding ws/dgat (wax ester synthase/acyl-coenzyme A: diacylglycerol acyltransferase) and a method of producing fatty acid ethyl esters using the same. Specifically, the transformant for producing fatty acid ethyl esters is constructed such that glycerol is used as a fermentation substrate, and comprises an atfA gene encoding ws/dgat (wax ester synthase/acyl-coenzyme A: diacylglycerol acyltransferase) from Acinetobacter sp., so that the atfA gene is expressed in the transformant.
US08652812B2	Dual oligonucleotide method of nucleic acid detection Methods for amplifying and detecting nucleic acids are described, as well as sets of 5′ labeled oligonucleotides.
US08652811B2	Dry composition of reaction compounds with stabilized polymerase The present invention provides methods to obtain dry compositions of reaction compounds that maintain the biological activity of the compounds upon re-solubilization after a certain storage time. Preferably, the dry composition comprises a polymerase, and the dry composition is usable for polymerase chain reaction (PCR) amplification after re-solubilization.
US08652804B2	Transcription factor-based biosensors for detecting dicarboxylic acids The invention provides methods and compositions for detecting dicarboxylic acids using a transcription factor biosensor.
US08652797B2	Methods of NAD-dependent deacetylation of a lysine residue in a protein Methods of NAD-dependent of at least one lysine residue in an acetylated protein are disclosed. The methods include combining the acetylated protein with an isolated Sir2 protein or fragment that includes a core domain of the Sir2 protein. The Sir2 protein or fragment of the Sir2 protein can include a human Sir2 protein or a fragment of a human Sir2 protein.
US08652792B1	Mutant bacterial strains of the genus Sphingomonas deficient in production of polyhydroxybutyrate and a process of clarification of sphingans and compositions thereof The invention relates to mutant strains of the genus Sphingomonas which have a mutation in at least one gene encoding a protein involved in polyhydroxybutyrate (“PHB”) synthesis that allows the mutant strains to produce PHB-deficient Sphingans. The invention is also directed to a process for preparing a clarified Sphingan solution comprising heating aqueous Sphingan solution, in particular PUB-deficient Sphingan solution, to a clarification temperature of about 30° C. to about 70° C., and treating the solution with a clarification agent and enzymes. In addition, the invention is directed to a food or industrial product comprising a PHB-deficient and/or clarified Sphingan. One particular embodiment of the invention is directed to a clarified, PHB-deficient high-acyl gellan and the processes of making thereof.
US08652790B2	Conformational entropy in molecular recognition The present invention provides methods for the determination of the degree of molecular recognition of a protein with a ligand, including a first protein with a second protein. The methods may comprise determining the squared generalized order parameter (hereinafter, O) for at least one intramolecular bond of the first protein. The protein is then formed into a complex with a ligand. The value or values of O2 for the said at least one bond of the protein is then determined while the protein and the ligand are in the complex. The O value or values determined for the protein while the protein and the ligand are in a complex are compared or related to the O value or values determined for the uncomplexed protein.
US08652789B2	Diagnosis and prognosis of dipeptidyl peptidase-associated disease states A method is provided for the diagnosis or prognosis of a disease state, involving the measurement of a parameter of discriminated dipeptidyl dipeptidases from a patient sample, and the correlation of the parameter with a disease.
US08652786B2	Method for predicting responsiveness to drugs The present invention provides a novel method to determine the likelihood of effectiveness of a treatment in an individual affected with or at risk for developing cancer. The method involves detecting the presence or absence of Met amplification in an individual. The presence of Met amplification indicates that a Met targeting treatment is likely to be effective. Preferably, the Met targeting treatment is PHA-665752 or PF-02341066. In addition, the present methods allow for the detection of cancer in an individual, wherein the presence of Met amplification indicates that cancer is present and further that it will be treatable, namely with a Met targeting treatment.
US08652785B2	Method of screening a modulator of endothelial NO synthase comprising the use of heme binding protein 1 The present invention relates to a method of screening for a modulator of endothelial NO synthase (eNOS) expression, a method of diagnosing a cardiovascular disease in a subject, the use of HEBP-1 for the identification of a medicament for preventing and/or treating a disease involving eNOS dysfunction, particularly a cardiovascular disease, the use of HEBP-1 for the detection of a component of eNOS signal transduction, and the use of HEBP1 for the regulation of eNOS promoter activity.
US08652784B2	DNA recombination junction detection The present invention provides methods, compositions and kits for detecting the presence or absence of an integrated insertion polynucleotide.
US08652782B2	Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids Disclosed are compositions and methods for isolating, detecting, amplifying, and quantitating Mycobacterium-specific nucleic acids in a sample. Also disclosed are compositions and diagnostic kits comprising Mycobacterium IS6110-specific oligonucleotide amplification primers and labeled oligonucleotide detection probes that specifically bind to the amplification products obtained therefrom. Also disclosed are compositions and methods for the isolation and characterization of nucleic acids that are specific to one or more tubercular pathogens, including Mycobacterium tuberculosis, in particular, from a wide variety of samples including those of biological, environmental, clinical and/or veterinary origin.
US08652781B2	Cognate sampling kinetics Provided are methods and compositions for measuring the transient binding of nucleotides and nucleotide analogs under conditions where the nucleotides or nucleotide analogs are unincorporable. The transient binding can be determined under single molecule observation conditions providing information about the kinetics of nucleotide analog sampling of the active site of the enzyme. The methods can be used for polymerase enzyme development, mechanistic understanding, and drug discovery.
US08652778B2	Use of photopolymerization for amplification and detection of a Molecular Recognition Event The invention provides methods to detect molecular recognition events. The invention also provides methods to detect the presence of or identify a target species based on its interaction with one or more probe species. The methods of the invention are based on amplification of the signal due to each molecular recognition event. The amplification is achieved through photopolymerization, with the polymer formed being associated with the molecular recognition event. In one aspect, a fluorescent polymer, a magnetic polymer, a radioactive polymer or an electrically conducting polymer can form the basis of detection and amplification. In another aspect, a polymer gel swollen with a fluorescent solution, a magnetic solution, a radioactive solution or an electrically conducting solution can form the basis of detection and amplification. In another aspect, detectable particles can be included in the polymer formed. In another aspect, sufficient polymer forms to be detectable by visual inspection.
US08652777B2	Method for the analysis of ovarian cancer disorders The invention relates to a method for the analysis of ovarian cancer disorders, comprising determining the genomic methylation status of one or more CpG dinucleotides in a sequence selected from the group of sequences according to SEQ ID NO. 1 to 10 and/or SEQ ID NO. 50 to SEQ ID NO. 60. Optionally, additionally following steps are performed, the one or more results from the methylation status test is input into a classifier that is obtained from a Diagnostic Multi Variate Model, calculating a likelihood as to whether the sample is from a normal tissue or an ovarian cancer tissue and/or, calculating an associated p-value for the confidence in the prediction.
US08652776B2	Prediction of QT prolongation based on SNP genotype The present invention relates to the prediction of QT prolongation following administration of a compound capable of increasing an individual's QT interval based on the individual's genotype at one or more single nucleotide polymorphism (SNP) loci and to the treatment of a patient based on such prediction.
US08652774B2	Automated method of manufacturing polyer arrays The present invention provides methods to process multiple sensors by providing a sensor plate and HT plates. In a preferred embodiment of the invention, methods for assembling microarray pegs and microarray plates are described for high throughput microarray processing.
US08652773B2	Genes of an otitis media isolate of nontypeable Haemophilus influenza The invention relates to the polynucleotide sequence of a nontypeable stain of Haemophilus influenzae (NTHi) and polypeptides encoded by the polynucleotides and uses thereof. The invention also relates to NTHi genes which are upregulated during or in response to NTHi infection of the middle ear and/or the nasopharynx.
US08652765B2	Making a microfluidic device with improved adhesion A method for making a microfluidic device, the method includes providing at least one inorganic layer on a substrate; applying an alkoxysilane material containing a primary or secondary amine on the at least one inorganic layer; baking the applied alkoxysilane material at a temperature greater than 130 degrees C.; applying an epoxy material to form an epoxy layer, wherein the applied alkoxysilane material is disposed at an interface between the epoxy layer and the at least one inorganic layer; and patterning the epoxy layer to provide a wall for defining a location for a fluid in the microfluidic device.
US08652764B2	Method for manufacturing a piezoelectric membrane type device A substrate 20 is prepared. “A piezoelectric material layer 32a which has not been fired” and which will become a piezoelectric membrane is formed above a first principal surface 20a of the substrate 20. A first mask 131 is formed above the piezoelectric material layer 32a. “The piezoelectric material layer 32a existing within a portion where the first mask 131 does not exist” is eliminated by injecting a blast media including at least one of abrasive grains or an organic solvent onto the first principal surface 20a of the substrate 20. Thereafter, the first mask 131 is eliminated, and the piezoelectric material layer 32a is fired. The substrate has a hollow portion, however, it does not necessarily have the hollow portion.
US08652758B2	Lithographic imaging and printing with printing members having fusible polymeric particles Embodiments of the present invention involve printing members that utilize a particle-fusion imaging mechanism but avoid susceptibility to handling damage. In particular, printing plates in accordance with the invention may utilize two phases, and these may originate, during manufacture, as two particle systems. Both systems are initially dispersed in a single coating applied as a layer, or in multiple coatings applied as adjacent layers, on a substrate. The second particle system exhibits a glass-transition or thermal coalescing temperature well above room temperature and also above the temperature at which the coating is dried. The coalescing temperature of the first particle system is below the drying temperature. As a result, when the coating is dried, the first particle system coalesces and forms a binder that entrains the second particle system, which has not coalesced. The binder formed by the first particle system is preferably insoluble in aqueous liquids, but is swellable or softened by such liquids, whereas the binder formed by the second particle system is preferably insoluble in and not swellable by aqueous liquids. Aqueous insolubility allows the dried (and ready-to-image) coating to resist handling damage, while swellability facilitates development.
US08652752B2	Sulphonium salt initiators Compounds of the Formula (I), wherein L1, L′1, L″1, L2, L′2, L″2, L3, L′3, L″3, L4, L′4 and L″4 for example are hydrogen or COT; R, R′ and R″ for example are hydrogen, C6-C12aryl or C3-C20heteroaryl; X, X′ and X″ for example are O, S, single bond, NRa or NCORa, T is for example hydrogen, C1-C20alkyl, C3-C12cycloalkyl, C2-C20alkenyl, C5-C12cycloalkenyl, C7-C18cycloalkylenaryl, C5-C18cycloalkylenheteroaryl, C6-C14aryl, providedthat at least one of R, R′ or R″ is unsubstituted or substituted C3-C20heteroaryl; and Y is an inorganic or organic anion; are suitable as photolatent acid generators.
US08652750B2	Silicon-containing film-forming composition, silicon-containing film, silicon-containing film-bearing substrate, and patterning method A silicon-containing film is formed from a heat curable composition comprising (A) a silicon-containing compound obtained through hydrolytic condensation of a hydrolyzable silicon compound in the presence of an acid catalyst, (B) a hydroxide or organic acid salt of Li, Na, K, Rb or Ce, or a sulfonium, iodonium or ammonium compound, (C) an organic acid, (D) a cyclic ether-substituted alcohol, and (E) an organic solvent. The silicon-containing film ensures effective pattern formation, effective transfer of a photoresist pattern, and accurate processing of a substrate.
US08652748B2	Process for producing a toner for electrophotography The invention provides a process for producing a toner for electrophotography including the following (1) to (4): (1): adding an aggregating agent to a resin particle dispersion (a) so as to attain an aggregating agent concentration Ea (wt %), to thereby produce an aggregated particle dispersion (A); (2): adding a resin microparticle dispersion (b) to the dispersion (A), to thereby produce a dispersion (B) having an aggregating agent concentration Eb (wt %) satisfying 0.60≦Eb/Ea<1; (3): modifying the aggregating agent concentration of the dispersion (B), to thereby produce a dispersion (C) of resin microparticle-deposited aggregated particles, having an aggregating agent concentration Ec (wt %) satisfying 0
US08652747B2	Continuous production of fine toner A continuous process for forming fine toner using a twin screw extruder.
US08652740B2	Balancing discharge area developed and transferred toner Printing methods are provided. In one aspect, at least one first toner image is formed and transferred onto a receiver to form a composite toner image on a receiver having a first polarity. A second net development difference of potential of the first polarity is created between a second development station, a bias member and the first toner at each location of the receiver, to cause a second toner of the first polarity to deposit at individual locations on the receiver in amounts that according to the second net development difference of potential at the individual locations such that total amount of first toner and any second toner deposited at each location on the receiver is within a range that is less than a range of first toner amounts on the receiver.
US08652739B2	Electrostatic image developing toner, electrostatic image developer, toner cartridge, process cartridge, image forming apparatus and image forming method The present invention provides a toner for developing an electrostatic charge image including toner particles having residual ammonium ions and silica particles containing a chlorine compound as an external additive.
US08652731B2	Electrostatic image developing toner, electrostatic image developer, toner cartridge, process cartridge, image forming apparatus and image forming method An electrostatic image developing toner includes (A) an amorphous polyester resin containing at least a repeating unit derived from a dicarboxylic acid component and a repeating unit derived from a dialcohol component represented by the specific formula, and (B) an amorphous polyester resin differing in the weight average molecular weight from the amorphous polyester resin (A), wherein the difference (absolute value) in the weight average molecular weight between the amorphous polyester resin (A) and the amorphous polyester resin (B) is from about 30,000 to about 100,000.
US08652725B2	Toner A toner having toner base particles each of which contains at least a binder resin and a colorant, and silica titania composite particles. The silica titania composite particles contain silica in an amount of from 55.0% by mass to 85.0% by mass; and, in a chart obtained by the measurement by X-ray diffraction of the silica titania composite particles and where, in respect of a peak having the highest diffraction intensity and a peak having the next-highest diffraction intensity among peaks present in the range of 2θ=24.0 to 29.0, the value of area of the peak on the lower-angle side is represented by Xa and the value of area of the peak on the higher-angle side is represented by Xb, the ratio of Xa/Xb is from 95/5 to 75/25.
US08652720B2	Super low melt toners Environmentally friendly latex particles are provided which include a gelling agent and a pigment encapsulated in an amorphous resin which may be utilized in forming EA super low melt toners. Methods for providing these resins and toners are also provided.
US08652715B2	Low torque overcoat for imaging device An overcoat containing a copolymer of a first propylene monomer and a second hydrophilic monomer provides superior wear resistance and low torque to a photoreceptor.
US08652711B2	Pellicle for lithography There is provided a pellicle in which the mask-bonding agglutinant layer has the adhesion strength of 1 N/m through 100 N/m, preferably 4 N/m through 80 N/m, and more preferably the agglutinant layer has a facial flatness of 15 micrometers or smaller, and still more preferably the membrane-bonding adhesive layer has a facial flatness of 15 micrometers or smaller: for the purpose of better preventing the pellicle frame from affecting the mask to deform.
US08652703B2	Production of self-supporting ceramic materials having a reduced thickness and containing metal oxides The present invention relates to a method for manufacturing a metal-oxide-based ceramic, including, in order, the step of inserting, into a flash sintering device, a nanocrystalline powder comprising crystallites and crystallite agglomerates of a ceramic of formula, Zr1-xMxO2, where M is chosen from yttrium, scandium and cerium, or Ce1-xM′xO2, where M′ is chosen from gadolinium, scandium, samarium and yttrium, where x lies between 0 and 0.2, the powder having an average crystallite size of between 5 and 50 nm, an average crystallite agglomerate size of between 0.5 and 20 μm, and a specific surface area of between 20 and 100 m2/g. The invention further includes the step of flash sintering the powder by applying a pressure of between 50 and 150 MPa, at a temperature of between 850° C. and 1400° C., for a time of between 5 and 30 minutes.
US08652698B2	Fuel cell, fuel cell system, and control method of fuel cell system A fuel cell has multiple cells, the multiple cells including a first cell having a first fuel gas flow path, and a second cell having a second fuel gas flow path and a sensor that measures a specific parameter value relating to a decrease in concentration of fuel gas in the second fuel gas flow path.
US08652697B2	Controlling a fuel cell system based on fuel cell impedance characteristic A method of controlling a fuel cell system includes applying alternating current (AC) signals to an individual fuel cell. The AC signals have a plurality of different frequencies. A voltage across the individual fuel cell is determined at each of the plurality of different frequencies. An impedance characteristic of the individual fuel cell is determined based at least in part on the voltage across the individual fuel cell at each of the plurality of different frequencies. The individual fuel cell is controlled based at least in part on the impedance characteristic.
US08652696B2	Integrated hydromethanation fuel cell power generation The present invention relates to processes and apparatuses for generating electrical power from certain non-gaseous carbonaceous feedstocks through the integration of catalytic hydromethanation technology with fuel cell technology.
US08652692B2	Li/Air non-aqueous batteries Non-aqueous alkali metal (e.g., Li)/oxygen battery cells constructed with a protected anode that minimizes anode degradation and maximizes cathode performance by enabling the use of cathode performance enhancing solvents in the catholyte have negligible self-discharge and high deliverable capacity. In particular, protected lithium-oxygen batteries with non-aqueous catholytes have this improved performance.
US08652687B2	Conductive graphene polymer binder for electrochemical cell electrodes The present invention provides an electrically conductive electrode comprising particles of an electroactive material and a conductive graphene polymer binder that bonds multiple particles of the electroactive material together, wherein the binder is in an amount of from 0.01% to 90% by weight based on the total electrode weight. Also provided are (a) a precursor solution or suspension to the graphene polymer binder for the electrode; (b) a paste containing electroactive particles and a graphene polymer dispersed in a liquid; (c) a method of producing the electrode from the precursor paste; and (d) an electrochemical cell (a battery or supercapacitor) containing such an electrode.
US08652684B2	Composition for negative electrode of alkaline electrolyte battery The invention proposes a composition comprising: a) a hydrogen-fixing alloy of formula R1-tMgtNis-zMz in which: R represents one or more elements chosen from the group comprising La, Ce, Nd and Pr; M represents one or more elements chosen from the group comprising Mn, Fe, Al, Co, Cu, Zr and Sn; 0.1≦t≦0.4; 3.0≦s≦4.3; z≦0.5; b) a manganese compound in a proportion such that the mass of manganese represents from 1 to 5.5% of the mass of the alloy, c) an yttrium compound in a proportion such that the mass of yttrium represents from 0.1% to 2% of the mass of the alloy. The invention also relates to an anode comprising the composition according to the invention.The invention also relates to an alkaline electrolyte battery comprising said at least one anode.
US08652683B2	High capacity electrodes A high capacity electrode includes a conducting substrate on which a plurality of support filaments are disposed. Each of the support filaments have a length substantially greater than their width and may include, for example, a carbon nano-tube (CNT), a carbon nano-fiber (CNF), and/or a nano-wire (NW). The support filaments are coated with a material, such as silicon, having a greater ion absorbing capacity greater than the neat support filaments. A trunk region of the support filaments proximate to the substrate is optionally kept free of ion absorbing material. This trunk region allows for the expansion of the ion absorbing material without detaching the support filaments form the substrate.
US08652681B2	Secondary battery having a stepped can and an insulation case with at least one projection Disclosed is a secondary battery, which includes: an electrode assembly; a can receiving the electrode assembly; and an insulation case provided at an upper part of the electrode assembly inside the can, where a stepped part thinner than the can is formed on an inner surface of an upper part of the can. The insulation case can be inserted to the stepped part and the cap plate can be seated on a second stepped part formed at the upper part of the stepped part and can have protrusions that contact the stepped part. The insulation case and cap plate are stably assembled to the can, thereby improving reliability of the process to weld the cap plate to the upper part of the can.
US08652678B2	Battery pack system Various embodiments are described herein for a system for providing electric power during use. The battery pack system includes at least one cell carrier assembly configured to provide electric current during use. The cell carrier assembly has a substantially planar configuration. The battery pack system further includes a battery pack enclosure for housing the at least one cell carrier assembly. The battery pack enclosure has at least one wall with at least one channel sized to receive an edge of the cell carrier assembly to locate the cell carrier assembly at a location within the battery pack enclosure and provide a thermal pathway during use.
US08652676B2	Assembled battery system with cooling member between adjacent cells The assembled battery system according to the present invention includes at least two non-aqueous electrolyte secondary cells, each including a positive electrode that occludes and emits lithium ions, a negative electrode that occludes and emits lithium ions, and a non-aqueous electrolyte comprising an electrolyte dissolved in a non-aqueous solvent, all received in a parallelepiped cell case. These cells are arranged so that each larger area side of an adjacent pair of the parallelepiped cell case faces in parallel one another. A cooling member with a cooling medium flow conduit is provided between each opposing pair of larger area cell case sides, and cooling medium flowing in this conduit directly contacts the sides of the parallelepiped cell cases that define the two opposite sides of the cooling conduit.
US08652673B2	Solid lithium secondary cell, and production method therefor A solid electrolyte layer and electrode layers are formed within an electrically insulating frame part, and current collecting plates are held by the electrically insulating frame part. Since the current collecting plates are held by the frame part, the shifting or coming-apart of the current collecting plates can be restrained. In order to cause the current collecting plates to be held by the frame part, a powder of material of the electrode layer is filled in between the frame part and the current collecting plates.
US08652669B2	Lead-acid battery A lead-acid battery comprising a container having at least one cell chamber and a lid body for covering a top opening of the container. The lid body has on a top surface a recessed portion having therein an annular portion protruding upward and having, in an area of a bottom wall inside the protruding portion, an exhaust hole for exhausting gas from the cell chamber, wherein a guide passage for guiding gas from the exhaust hole to the outside is formed by joining the protruding portion with a joining portion provided on the lid body cover. An annular groove formed between the protruding portion and the vertical wall is covered with an outer periphery of the lid body cover 5 and the guide passage is isolated from the groove.
US08652656B2	Triphenylene silane hosts Novel aryl silicon and aryl germanium host materials, and in particular host materials containing triphenylene and pyrene fragments, are described. These compounds improve OLED device performance when used as hosts in the emissive layer of the OLED.
US08652654B2	Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same A biscarbazole derivative of the invention is represented by a formula (1) below. In the formula (1): A1 represents a substituted or unsubstituted nitrogen-containing heterocyclic group having 1 to 30 ring carbon atoms; A2 represents a substituted or unsubstituted aromatic hydrocarbon group having 6 to 30 ring carbon atoms, or substituted or unsubstituted nitrogen-containing heterocyclic group having 1 to 30 ring carbon atoms; X1 and X2 each are a linking group; Y1 to Y4 each represent a substituent; p and q represent an integer of 1 to 4; and r and s represent an integer of 1 to 3.
US08652653B2	Hole transport materials having a sulfur-containing group Novel materials are provided, having a single phenyl or a chain of phenyls where there is a nitrogen atom on each end of the single phenyl or chain of phenyls. The nitrogen atom may be further substituted with particular thiophene, benzothiophene, and triphenylene groups. Organic light-emitting devices are also provided, where the novel materials are used as a hole transport material in the device. Combinations of the hole transport material with specific host materials are also provided.
US08652652B2	Single triphenylene chromophores in phosphorescent light emitting diodes Novel triphenylene compounds are provided. Specific examples include multi-aryl-substituted triphenylenes. A preferred group of compounds are triphenylenes that are substituted with a non-fused aryl group having one or more meta-substituents, where each meta-substituent is a non-fused aryl group optionally substituted with further substituents selected from the group consisting of non-fused aryl groups and alkyl groups. A further preferred group of compounds are triphenylenes that are substituted with a non-fused heteroaryl group having one or more meta-substituents, where each meta-substituent is a non-fused aryl or heteroaryl group optionally substituted with further substituents selected from the group consisting of non-fused aryl groups, non-fused heteroaryl groups, and alkyl groups. Some high triplet energy analogs are expected to work with deep blue phosphorescent dopants. The compounds may be useful in phosphorescent organic light emitting devices. Also provided is an organic electroluminescent device comprising an anode, a cathode, and an emissive layer between the anode and the cathode, the emissive layer comprising a phosphorescent material and a compound having a repeat unit, the repeat unit containing a triphenylene moiety.
US08652651B2	Photoluminescent sheet A photoluminescent sheet is disclosed. In one embodiment, the photoluminescent sheet includes i) a phosphor, for absorbing some light, of at least one wavelength, of light emitted from a light source and emitting particular light of a wavelength different from the wavelength of the emitted light, ii) a matrix, for having the phosphor, the remaining of the light emitted from the light source penetrating the matrix and iii) a passivation film, for being laminated to at least one surface of the matrix, whereas a roughness is formed on a surface of the passivation film to reduce a contacting area between the photoluminescent sheet and another sheet. According to one embodiment of the present invention, wet is not generated on a screen even though the photoluminescent sheet is connected to other sheets.
US08652647B2	Articles comprising phyllosilicate composites containing mica Disclosed is a mica paper composite and a process for making the mica paper composite. Articles comprising the mica paper composite are also disclosed.
US08652644B2	Lid for closing a cup A lid (2) for closing a cup (1) along a peripheral sealing edge (10) and a method for producing such a lid. The lid includes at least one aluminum film and an optionally multi-layered plastic layer which is co-extruded onto the aluminum film and has a closed predetermined tearing line (3). The plastic layer is made of plastic based on polyethylene (PE) or plastic based on polypropylene (PP), and the predetermined tearing line is introduced into the plastic layer preferably by means of a CO2 laser. The predetermined tearing line (3) may be provided directly in the region of the sealing edge (10).
US08652641B2	Heat conductive dielectric polymer material and heat dissipation substrate containing the same A heat conductive dielectric polymer material comprises a polymer, a curing agent and a heat conductive filler. The polymer comprises a thermoplastic and a thermosetting epoxy resin. The thermoplastic comprises 3% to 30% by volume of the heat conductive dielectric polymer material, and the thermosetting epoxy is selected from end-epoxy-function group epoxy resin, side chain epoxy function group epoxy resin, multi-function group epoxy resin or the mixture thereof. The curing agent can cure the thermosetting epoxy resin at a temperature. The heat conductive filler is uniformly distributed in the polymer and comprises 40% to 70% by volume of the heat conductive dielectric polymer material. The heat conductive dielectric polymer material has an interpenetrating network structure, and the heat conductive coefficient is greater than 1.0 W/m-K.
US08652634B2	Fibrous structures Fibrous structures that exhibit a Geometric Mean Elongation of greater than 15.8% as measured according to the Elongation Test Method are provided.
US08652629B2	Transmission cross arm A cross arm is provided, for use in a support structure for conductors within an electrical grid. The cross arm is made of weather resistant glass fiber reinforced two component polyurethane based polymers and has a “C” cross sectional shape typically arranged in a double configuration. Pairs of the cross arms are attached to utility poles in a parallel position on opposite sides of the utility pole to meet predefined design conditions. Alternatively, a single cross arm may be attached to a utility pole.
US08652626B2	Biaxially oriented metallized polylactic acid film with high metal adhesion and high barrier properties Metallized multi-layer biaxially oriented polylactic acid base polymer (BOPLA) films that exhibits improved barrier properties and metal adhesion. The films include a core layer including crystalline polylactic acid base polymer, a first skin layer consisting essentially of amorphous polylactic acid base polymer, and a metal layer on the first skin layer. The films may include a second skin layer consisting essentially of amorphous polylactic acid base polymer.
US08652625B2	Transparent gas barrier film A transparent gas barrier film comprising a substrate having thereon a gas barrier layer comprising at least a low density layer and a high density layer, wherein one or more intermediate density layers are sandwiched between the low density layer and the high density layer.
US08652616B2	System and method for reducing a re-floccing tendency a nanomilled calcium carbonate A method for forming a printable coating includes providing a calcium carbonate, combining a dispersant with the calcium carbonate, nanomilling the calcium carbonate and the dispersant to inhibit re-floccing of the nanomilled calcium carbonate, and combining the mixture with a binder at alkaline pH. According to one exemplary embodiment, the coating may be applied to one or more sides of a media substrate.
US08652613B2	Quadruple-wall corrugated paperboard and method of manufacture A corrugated paperboard for the packaging industry comprising of five liners (1a, 1b, 1c, 1d, 1e) and four intermediate corrugating mediums (2a, 2b, 2c, 2d) with flute type combination of B-C-B-C; thereby providing robust, greater compression strength, yet capable of economically produce corrugated paperboard by utilizing the method of combining paperboard using corrugator to produce doublewall and sheet pasting machine to make the final combination of a quadruple-wall paperboard.
US08652610B2	Water-dispersible creping materials Fibrous products are disclosed containing an additive composition. The additive composition, for instance, comprises a water-soluble film forming component, a first water-soluble modifier component and a hydrophobic polymer component. In some aspects, the additive composition further comprises an additional water-soluble modifier component. The additive composition may be incorporated into the fibrous web by being combined with the fibers that are used to form the web. Alternatively, the additive composition may be topically applied to the web after the web has been formed. In one aspect, the additive composition may be applied to the web as a creping adhesive during a creping operation. The additive composition may improve the perceived softness of the web without substantially affecting the absorbency of the web in an adverse manner.
US08652609B2	Corner plate with sled feature A corner plate for connecting pieces of duct that facilitates automatic feeding and provides horizontal stack stabilization. The corner plate includes sled features that provide regular and even vertical spacing when stacked. The sled features also interact with an adjacent corner plate allowing motion in a feed direction to facilitate automatic feeding while resisting lateral motion in a non-feeding direction to stabilize the stack of corner plates in a horizontal direction. The corner plate also includes tabs that prevent nesting and facilitate automatic feeding.
US08652607B2	Image recording media and imaging layers Imaging layers, optical disks, and methods of preparation of each, are disclosed.
US08652601B2	Cover film A cover film comprising a substrate layer, an intermediate layer comprising a resin composition containing 50% by mass or more of a metallocene linear low-density polyethylene resin having a density of 0.900 to 0.940×103 kg/m3, and a sealant layer comprising an ethylene-type copolymerized resin containing 50 to 85% by mass of an olefin component.
US08652598B2	Packaging materials with enhanced thermal-insulating performance A thermo-insulating packaging material including a paper-based substrate layer, a paper-based top layer and a thermal-insulating composition positioned between the paper-based substrate layer and the paper-based top layer, the thermal-insulating composition including a filler, an organic binder and a plasticizer.
US08652596B2	In-mold molded product, in-mold molding film, and method for producing in-mold molded product An in-mold molded product of the present invention includes: molded resin; a transfer film sequentially including an adhesive layer in contact with the molded resin, and a coloring layer formed of ink; and a plurality of inorganic filler pieces contained in the coloring layer.
US08652592B2	Discrimination medium and discrimination method for discriminating the same A discrimination medium on which printing can be freely performed, which cannot be easily falsified, in which the authenticity can be easily discriminated by unique appearance, and which can be produced at low cost, is provided. A cholesteric liquid crystal layer 10, and a breakable print recording layer are laminated in the discrimination medium. The cholesteric liquid crystal layer 10 has plural light transparent films, which are laminated and are different from each other in refraction index. Therefore, the discrimination medium has unique optical characteristics such that a character, a symbol, a pattern, a figure formed by printing by a thermal printer or the like changes in color depending on the viewing angle. A discrimination method using the above optical characteristics of the discrimination medium is provided.
US08652585B2	Method for coating a component The invention relates to a method for coating a component (16), wherein the component (16) is provided with at least one coating layer that can be cured by applying UV light, said layer having UV light applied thereto in an exposure chamber (14) comprising a substantially spherical or ellipsoidal interior (18), wherein the at least one coating layer is applied to the component (16) in a coating chamber (12) comprising the exposure chamber (14).
US08652582B2	Method of making ligand functionalized substrates Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed. The ligand functionalized substrate may be described as the grafted reaction product of a substrate and a ligand monomer of Formula I:
US08652580B2	Manufacturing method of tiles A manufacturing method of tiles includes the steps of: preparing mixed powder having a water content of 2 to 7% by mixing 30 to 80 parts by weight of calcium hydroxide powder or dolomite plaster powder, 20 to 70 parts by weight of porous aggregate, 0.1 to 5 parts by weight of a first photocatalyst and water; filling the mixed powder into a mold of a molding machine; forming a formed body by pressurizing the filled mixed powder; curing the formed body in a carbon dioxide atmosphere; and forming a thin layer made of a second photocatalyst on a surface of the formed body.
US08652579B2	Processes of making fiber-containing composites from polyamic acid-containing binder compositions Processes are described for binding a fibrous material. The processes may include applying to a surface of the fibrous material an aqueous binding composition to form a coated fibrous material. The binding composition may include: (a) a water-soluble polyamic acid, and (b) an organic crosslinking agent capable of undergoing a covalent crosslinking reaction with the water-soluble polyamic acid when heated. The water-soluble polyamic acid may be formed by the reaction of: a (i) a polycarboxylic acid or polyanhydride having a molecular weight of at least 150 g/mol, and (ii) ammonia or an amine compound. The processes may further include heating the coated fibrous material to crosslink the water-soluble polyamic acid with the organic crosslinking agent to form a cured binder. One or more adjoining fibers of the fibrous material may be bound to each other at cross over points by the cured binder.
US08652577B2	Method of manufacturing cathode active material A method of manufacturing a cathode active material is provided. The method includes the step of precipitating step for providing a solution of a deposition component onto composite oxide particles including lithium Li and nickel Ni, removing a solvent from the solution on the composite oxide particles within a short time period, and precipitating the deposition component on surfaces of the composite oxide particles; and heating step for heating under an oxidation atmosphere the composite oxide particles with the deposition component precipitated on the surfaces.
US08652573B2	Method of CVD-depositing a film having a substantially uniform film thickness Method of depositing a film having a substantially uniform thickness by means of chemical vapor deposition, comprising: providing a reaction chamber; providing a substrate in said reaction chamber; subjecting the substrate to a series of deposition cycles, wherein each deposition cycle includes the steps of: (a) during a first time interval, supplying a first reactant to the reaction chamber; (b) during a second time interval, supplying a second reactant to the reaction chamber; and (c) during a third time interval, supplying neither the first nor the second reactant to the reaction chamber; wherein a start of the second time interval lies within the first time interval, such that a pre-exposure interval exists between a start of the first time interval and the start of the second time interval, during which pre-exposure interval the first reactant is supplied to the reaction chamber while the second reactant is not.
US08652572B2	Method to produce particulate filter A method is provided for producing a particulate filter to pass through select permeate particles in a fluid medium from inflow to outflow regions while restraining reticulate particles. The method includes providing an aluminum oxide substrate; disposing a sol-gel membrane onto the substrate to form a tiered filtration unit; drying the filtration unit; and calcinating the filtration unit.
US08652569B2	Optical waveguide production method An optical waveguide production method is provided which reduces a transmission loss, improves alignment mark visual detectability, and ensures excellent productivity. In the optical waveguide production method, an under-cladding layer, a core and an alignment mark are formed on a surface of a metal substrate. On the other hand, a molding die is prepared which includes a cavity and an alignment mark to be associated with the alignment mark. In turn, light emitted from the side of the molding die is utilized for positioning the metal substrate and the molding die with reference to the pair of associated alignment marks. Then, an over-cladding layer is formed over the core. The alignment mark is formed from a photo-curable composition comprising the following components (A) and (B): (A) a polymerizable composition having a (meth)acrylate group; and (B) a photoradical polymerization initiator.
US08652565B2	Sealing method of sealing dispersion liquid containing and electrophoretic particles, and electrophoretic display A sealing method is applicable to a cell matrix equipped with a plurality of cells spatially divided by a partition for sealing dispersion liquid containing hydrophobic dispersion medium and electrophoretic particles dispersed therein in the cells. The sealing method includes: supplying the dispersion liquid in the cells through an opening section of a space defined by the partition; and forming a sealing layer at an exposed portion of the dispersion liquid in the opening section, using a polymer reaction at an interface with water.
US08652563B2	Nutrient composition The present invention relates to a nutrient composition which contains at least a carbohydrate, a lipid, a protein, and a mineral, and is liquid or semisolid, characterized in that the volume-based median size (d50) of particles in the nutrient composition is 5 to 100 μm and water-insoluble particles having a protein insolubilized by a divalent cation are contained as a major component of the nutrient composition, or a nutrient composition which contains at least a carbohydrate, a lipid, a protein, and a mineral, and is liquid or semisolid, characterized in that water-insoluble particles having a protein insolubilized by a divalent cation are contained as a major component of the nutrient composition and the mass of the protein with respect to the total moles of divalent ions forming the water-insoluble particles is 1.5 to 3 g/mmol.
US08652561B2	Frying method A method for frying foodstuffs, the method comprising a fryer having inlet and outlet longitudinal ends, an oil recirculating system coupled to the fryer, a heat exchanger for heating the oil in the oil recirculating system, a hood above the fryer for collecting steam generated during the frying process, a conduit for conveying steam from the hood, and a compressor for compressing the steam, the compressor having an input connected to the conduit and an output for compressed steam connected to the heat exchanger.
US08652557B2	Whole grain products made with whole grain durum wheat Whole grain baked products and mixes having milled whole grain durum wheat are provided. Whole grain durum baked products and mixes utilize milled whole grain durum flour having a generally white-like color wherein durum particulate matter is visually indistinguishable from durum fines by the unassisted eye. Through the use of milled whole grain durum flour, white-like whole grain durum products including white-like whole grain durum breads can be prepared that satisfy generally accepted color and baking performance characteristics for traditional white breads.
US08652556B1	Cooking method and cooker for cooking foodstuffs in stackable trays A cooking system and a method for cooking food products. The cooking system comprises a forced-convection cooker having a conveyor continuously conveying stacks of product-laden trays through a cooking chamber. Fans in the cooking chamber establish a generally vertical convection path traversed by the conveyor. Foraminous bottoms in the trays allow cooking fluid in the convection path to be forced through the trays and products.
US08652554B2	Method for preparing instant dried scorched rice with excellent resilience The present invention relates to a method for preparing instant dried scorched rice with excellent resilience, comprising washing a mixture of nonglutinous rice and glutinous rice, followed by soaking, adding polygonatum concentrate and rice starch, as a separate process, to the washed rice to prepare rice cooking water, followed by performing rice cooking to prepare cooked rice, mixing the cooked rice with purified water in a scorched rice forming apparatus to prepare scorched rice and grinding to prepare instant dried scorched rice. As the instant dried scorched rice prepared according to the method of the present invention has an internal texture having a developed network structure, and the scorched rice exhibits superior spreading and soft texture and the starch of the scorched rice is easily eluted to provide a predetermined turbidity, and to enrich the inherent flavor as well, and also the scorched rice soup exhibits superior qualities, comparable to traditional homemade scorched rice soup, and can be stored for a long period of time, thus being considerably useful for the food industry.
US08652553B2	Method and device for producing pureed food A method, device, and knife system for producing purëed, cooked foodstuffs from piece-form raw material. The method includes pre-chopping of the piece-form raw material in a pre-chopping unit, cooking of the pre-chopped raw material in a cooking plant, and final processing of the cooked product in a final-processing unit. Before cooking, the piece-form raw material is cut into small pieces by the pre-chopping unit such that a pumpable mass is produced from the piece-form raw material.
US08652552B2	Apparatus and a method for estimating the air humidity within an oven cavity The present invention relates to an apparatus for estimating the air humidity within an oven cavity (14) by using ultrasound waves with at least two different frequencies (f1, f2). Said apparatus comprises at least one ultrasound transmitter (10) for generating the ultrasound waves, at least one ultrasound receiver (12) for receiving the ultrasound waves and at least one phase detecting device for detecting the phase (φ1, φ2) of the ultrasound wave at the ultrasound receiver (12) relative to the same ultrasound wave with the same frequency (f1, f2) at the ultrasound transmitter (10). Said apparatus comprises further at least one evaluation unit for calculating the velocity (V) of the ultrasound waves on the basis of the phases (φ1, φ2) and frequencies (f1, f2) of the ultrasound waves with the two different frequencies (f1, f2), at least one temperature sensor (32) for detecting the temperature (T) in the oven cavity (14) and at least one estimation unit for estimating the humidity in the oven cavity (14) on the basis of the temperature (T) and the velocity (V) of the ultrasound waves. Further, the present invention relates to a corresponding method for estimating the air humidity within an oven cavity (14).
US08652550B2	Health beverages comprising cinnamon extract and methods of making and using the same Described herein are beverages that provide a number of heath benefits associated with elevated or high blood sugar levels. For example, the beverages are useful in potentiating insulin activity, treating hyperglycemia, and maintaining blood sugar levels in a subject afflicted with diabetes. The beverages are composed of distilled water, cinnamon extract, and sweetener. Vitamins, minerals, and nutrients can be added to the beverage to provide additional health benefits.
US08652547B2	Process for preparing granules of hydrophilic active principle by extrusion The present invention relates to a process for preparing cores of granules intended for animal nutrition, the said cores comprising: a hydrophilic active principle present in an active content of greater than or equal to 60% by weight, at least one meltable binder, at least one plasticizer, the said process comprising (a) a first step of mixing of the ingredients, (b) a second step of extrusion of the mixture through an extruder, especially a single-screw or twin-screw extruder, equipped with one or more dies, so as to obtain rods, and (c) a third step of spheronization of the rods, the said process being characterized in that a preliminary dry co-grinding of the ingredients is performed before extruding the mixture, the said co-grinding being performed at a temperature of not more than 50° C. The present invention also relates to a process for preparing granules of hydrophilic active principle comprising the said cores.
US08652543B2	Cosmetic and/or pharmaceutical compositions and their applications Compositions are disclosed containing, as active ingredients, an extract of Allium species, an extract of Citrus species and either an extract of Paullinia species and an extract of Theobroma species, or an extract of Salix species and zinc sulphate, and the method of preparation of these compositions, and cosmetic and/or pharmaceutical application of these compositions.
US08652540B2	Method of using rhein for treating fibrotic conditions and tumors The present invention relates to a method of using an anthraquinone derivative namely 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid, or known as Rhein, for treating chronic pancreatitis induced fibrosis of the pancreas. More particularly, the present invention relates to a method of using Rhein, its derivatives and/or chemical variants as an anti-fibrotic agent. The present invention particularly relates to the suppression of pancreatic stellate cell activation for the management of chronic inflammatory, fibrotic and tumorigenic pathologies in the pancreas.
US08652538B2	Composition for accelerating change in muscle type The present invention provides a composition for accelerating a change in muscle type, increasing the amount of muscle, strengthening muscle, enhancing athletic abilities, reducing lipids, suppressing the accumulation of lipids, lowering blood sugar, controlling body weight or lowering body weight, containing a PPAR-δ promoter, an AMPK promoter and a PGC1-α promoter as an active ingredient.
US08652536B2	Skin clarifying complex, use of said complex, cosmestic or pharmaceutical composition comprising said complex and method for application thereof It is disclosed a skin clarifying complex comprising gallic acid and linoleic acid. It is further provided that the gallic acid can be obtained from Shinus sp and the linoleic acid can be obtained from passion flower oil. It is further disclosed the cosmetic or pharmaceutical use of the clarifying complex and a cosmetic or pharmaceutical composition comprising 0.25 to 10%, by weight, of said clarifying complex. The clarifying complex exhibits a high skin, spot and sprecke clarifying effect.
US08652531B2	Indicator for oxygen generation There is provided on-demand, oxygen generating topical compositions having a built-in indicator specifically to indicate a color change upon the complete mixing of the oxygen precursor and catalyst. The first part of the composition contains a carrier and manganese dioxide (MnO2) nanoparticles. The second part of the composition comprises the oxygen precursor; hydrogen peroxide. When the two parts, one with manganese dioxide nanoparticles and exhibiting a characteristic color, (e.g. yellow brown) and the second part with hydrogen peroxide are mixed together, the color imparted by the manganese dioxide nanoparticles essentially disappears and the final composition (enriched with oxygen) either appears colorless or takes on the original color of the catalyst. Thus, the manganese dioxide catalyst nanoparticles themselves serve as the colorimetric indicator of peroxide decomposition to oxygen, precluding the need for an external colorant. Manganese dioxide particles that are not nanoparticles fail to exhibit this color changing phenomenon.
US08652530B1	Preservation of the biological activity of undenatured type II collagen The instant invention is the storage of Type II collagen containing tissue in carbonated water. Such Type II collagen is useful for alleviating the symptoms of arthritis in mammals as well as the treatment of arthritis in mammals. Such Type II collagen is also useful for the prevention of arthritis in mammals. The instant invention is also a method for the preparation of a nutritional supplement that includes the steps of: (a) separating water-insoluble undenatured Type II collagen containing animal tissue from animal tissue not containing Type II collagen; (b) subdividing and sterilizing said tissue under conditions which do not change the original structure of the Type II collagen to produce a subdivided and sterilized product; (c) packaging the subdivided and sterilized product in carbonated water.
US08652528B2	Drug loaded polymeric nanoparticles and methods of making and using same The present disclosure generally relates to methods of making nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such as a diblock poly(lactic) acid-poly(ethylene)glycol.
US08652522B2	Pharmaceutical composition of an iontophoresis It is an object of the present inventions to produce a pharmaceutical composition for the iontophoresis wherein a drug stability is excellent, and it is easy to blend and fill up when manufactured and it is possible to manufacture at low cost. A pharmaceutical composition for an iontophoresis according to the present invention, is characterized in that the composition contains a nonionic synthetic polymer, betamethasone sodium phosphate and solvent. Furthermore, in a preferred embodiment of a pharmaceutical composition for an iontophoresis according to the present invention, the composition is characterized in that the nonionic synthetic polymer is polyvinyl alcohol (PVA). Furthermore, in a preferred embodiment of a pharmaceutical composition for an iontophoresis according to the present invention, the composition is characterized in that the mixing amount of the polyvinyl alcohol (PVA) is 0.5 to 30.0 percent by weight.
US08652521B2	Coated solid preparation A coated solid preparation includes an active ingredient including valproic acid or a pharmacologically acceptable salt thereof, and a coating layer containing polyvinyl alcohol and swelling clay coating the active ingredient wherein mass ratio of the polyvinyl alcohol to the swelling clay is 8:2 to 3:7 and the swelling clay is dispersed as a laminated structure.
US08652519B2	Dissolution properties of drug products containing olmesartan medoxomil A pharmaceutical tablet containing olmesartan medoxomil and amlodipine besylate, which has improved dissolvability. Said composition contains (A) olmesartan medoxomil and (B) amlodipine besylate as active ingredients and (C) a calcium-containing additive. A method of improving the dissolution properties of a pharmaceutical composition containing olmesartan medoxomil and amlodipine besylate by using said composition is also provided.
US08652517B2	Coating of tablet cores A process for the coating of tablet cores, said tablet core comprising an effective amount of at least one pharmaceutically active compound, comprising spraying a coating solution or suspension comprising a sugar, or a starch, or a mixture of a sugar and a starch onto the tablets or tablet cores with the proviso that film-forming agents in the coating solution or suspension are excluded, to obtain coated tablets, such coated tablets and corresponding coating mixtures.
US08652507B2	Juvenile cartilage composition The present invention is directed to compositions having at least one neocartilage particle, juvenile cartilage particle or a combination thereof and a matrix, and methods and devices that include the compositions.
US08652504B2	Solid polymer delivery compositions and methods for use thereof The present invention provides an implantable solid polymer delivery composition that can be formulated to release a bioactive agent to an interior body site at a controlled rate over an extended period of time by adjusting the various components of the composition. The controlled delivery of the composition avoids an initial drug spike, resulting in a smooth delivery profile over time. Polymer layers in the composition can be porous and are both biodegradable in water and body enzymes and biocompatible. Methods of making the implantable solid polymer compositions and methods of delivering a bioactive agent at a controlled rate to an interior body site are also provided.
US08652500B2	Particulate tissue graft with components of differing density and methods of making and using the same Disclosed are tissue graft compositions made of particles having different densities, methods of making these compositions, and methods of using these compositions for promoting tissue restoration in a patient.
US08652498B2	Pesticidal composition The present invention relates to an agricultural composition comprising sulphur in the range from 20% to 80% of the total composition, a chloronicotinyl compound in the range from 0.7% to 25% of the total composition, a pyrethroid compound in the range from 0.75% to 10% of the total composition and at least one agrochemically acceptable excipient
US08652496B2	Biocides and apparatus A biocide is formed by mixing at least one of ammonium sulfamate and ammonium carbamate with an aqueous solution of a hypochlorite oxidant at a molar ratio of ammonium to hypochlorite of at least 1:1. The biocide is useful in treating microbial or biofilm growth, pulp and paper process water, cooling tower water, waste water, reclaimed waste water, sludge, colloidal suspensions, irrigation water or a medium having a reducing capacity.
US08652494B2	Composition for cosmetic, pharmaceutical or dietary applications A composition including 0.5-40% vegetable extracts, 30-90% carbohydrate and 0.5-30% of phospholipid with 40-80% phosphatidylcholine for cosmetic, pharmaceutical or dietary uses.
US08652492B2	Wet granulation using a water sequestering agent Disclosed are tablets comprising hydrolytically stable formulations of (6-(5-fluoro-2-(3,4,5-trimethoxyphenylamino)pyrimidin-4-ylamino)-2,2-dimethyl-3-oxo-2H-pyrido[3,2-b][1,4]oxazin-4(3H)-yl)methyl phosphate disodium salt (Compound 1) prepared by a wet granulation process.
US08652491B2	Transdermal compositions for anticholinergic agents The present invention relates generally to compositions or formulations for transdermal or transmucosal administration of anti-cholinergic agents such as oxybutynin. The invention utilizes a novel delivery vehicle and is a substantially malodorous-free and irritation free transdermal formulation which is substantially free of long chain fatty alcohols, long-chain fatty acids, and long-chain fatty esters. A method is disclosed for administering such formulations to a person in need thereof while reducing the incidences of peak concentrations of drug and undesirable side effects associated with oral anti-cholinergics.
US08652488B2	Insulin B chain autoantigen composition The invention features methods for the prevention or treatment of autoimmune disorders in humans. The methods include administering an autoantigen in combination with an oil-based carrier. Included are methods for the prevention and treatment of diabetes mellitus which include treating a patient with a diabetes type 1 autoantigen, e.g., human insulin B-chain or GAD65, and an oil-based carrier approved for human use. Also included are vaccines and kits for the treatment of diabetes mellitus.
US08652484B2	Delivery system for cytotoxic drugs by bispecific antibody pretargeting The present invention relates to methods and compositions for pretargeting delivery of therapeutic agents. In preferred embodiments, the pretargeting method comprises: a) administering a bispecific antibody with a first binding site for a disease-associated antigen and a hapten on a targetable construct; b) administering a targetable construct comprising at least one therapeutic agent. In preferred embodiments, the bispecific antibody is made by the dock-and-lock (DNL) technique. In a more preferred embodiment, the targetable construct comprises one or more SN-38 moieties.
US08652483B2	Viral infection enhancing peptide The invention relates to a peptide derived from HIV-1 gp120 which forms insoluble aggregates when introduced into an aqueous solution and its use for enhancing viral infection of cells. In addition, the invention comprises methods for enhancing viral infection of cells, for concentrating a virus and for separating a virus from a fluid.
US08652480B2	Shortened purification process for the production of capsular Streptococcus pneumoniae polysaccharides A shortened process for producing a solution containing substantially purified capsular polysaccharides from a cellular Streptococcus pneumoniae lysate broth is described. Ultrafiltering and diafiltering a clarified S. pneumoniae lysate followed by pH adjustment to less than 4.5, preferably about 3.5, precipitated at least 98% of the protein in the solution without seriously affecting polysaccharide yield. Furthermore, following ultrafiltration and diafiltration and acidification to a pH of less than 4.5, filtration using activated carbon precipitated at least 90% of remaining protein without seriously affecting polysaccharide yield. Exemplary, non-limiting S. pneumoniae serotypes that can be purified using the shortened process of the invention are 1, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F. In one embodiment, the Streptococcus pneumoniae cells are lysed using deoxycholate sodium (DOC), while in another embodiment the lytic agent is a non-animal derived lytic agent such as N-lauryl sarcosine sodium (NLS).
US08652476B2	Pharmaceutical composition for treating ischemic events Methods and pharmaceutical compositions for treating severe ischemic events including cerebral infarction, cardiac infarction, or pulmonary embolism, comprising a thrombolytic intervention including thrombolytic agents and an inhibitor of vascular endothelial growth factor (VEGF) receptor-mediated signal transduction are disclosed.
US08652466B2	Methods for the treatment of disease using immunoglobulins having Fc regions with altered affinities for FcγRactivating and FcγRinhibiting The present invention relates to methods of treating or preventing cancer and other diseases using molecules, particularly polypeptides, more particularly immunoglobulins (e.g., antibodies), comprising a variant Fc region, wherein said variant Fc region comprises at least one amino acid modification relative to a wild-type Fc region, which variant Fc region binds an FcγR that activates a cellular effector (“FcγRActivating,” such as FcγRIIA or FcγRIIIA) and an FcγR that inhibits a cellular effector (“FcγRInhibiting,” such as FcγRIIA) with an altered Ratio of Affinities relative to the respective binding affinities of such FcγR for the Fc region of the wild-type immunoglobulin. The methods of the invention are particularly useful in preventing, treating, or ameliorating one or more symptoms associated with a disease, disorder, or infection where either an enhanced efficacy of effector cell function mediated by FcγR is desired (e.g., cancer, infectious disease) or an inhibited effector cell response mediated by FcγR is desired (e.g., inflammation, autoimmune disease).
US08652458B2	Tissue graft with non-aligned fiber matrix retains mesenchymal progenitor cells on the non-injury-facing side A graft containing a scaffold that includes a matrix in which are positioned mesenchymal progenitor cells (MPCs) has the capacity to substantially improve wound healing, including wounds resulting from injury to nerve, bone and vascular tissue. MPCs can be harvested from debrided muscle tissue following orthopaedic trauma. The traumatized muscle-derived progenitor cells are a readily available autologous cell source that can be utilized to effect or improve wound healing in a variety of therapeutic settings and vehicles.
US08652456B2	Aqueous preparations comprising at least one water-soluble or water-dispersible copolymer with cationgenic groups The present invention relates to aqueous preparations comprising at least one water-soluble or water-dispersible copolymer with cationogenic groups which comprises at least one monomer with at least one protonatable nitrogen atom and at least one further monomer copolymerizable therewith in copolymerized form, and at least one cosmetically acceptable carrier, where the pH of the aqueous preparation has a value in the range from pH 4 to pH 6.
US08652455B2	Targeted perhydrolases Disclosed herein are compositions and methods to target enzymatic peracid production to a target surface. The peracid benefit agent produced by the targeted perhydrolytic enzyme can be use for a variety of applications such as bleaching, whitening, disinfecting, destaining, deodorizing, and combinations thereof. Specifically, a fusion protein comprising a perhydrolytic enzyme and at least one peptidic component having affinity for a target surface (excluding body surfaces and oral care surfaces) is used in combination with a suitable substrate and a source of peroxygen to enzymatically produce a peracid on or near the surface of the target material. In a preferred aspect, the target surface is a cellulosic material.
US08652454B2	Composition Hair conditioner comprising silicone and a conditioning gel phase, said phase obtainable by heating a fatty alcohol and an oil until they are molten, separately heating a cationic surfactant in water until it is dissolved/suspended, then adding the molten fatty alcohol and oil mix to the cationic surfactant before adding any remaining ingredients.
US08652453B2	Hair cosmetic A new hair cosmetic composition containing (a) a 40-90 wt % volatile oil component, (b) 0.1-20 wt % a combination of polyoxyethylene, polyoxypropylene, butylene, dimethylpolysiloxane copolymers, and (c) 0.1-30 wt % ethanol. This hair cosmetic composition may be mainly used in a hair oil for superior sensation during use and superior stability over time.
US08652452B2	2,4-disubstituted pyridines as perfuming ingredients The present invention relates to the field of perfumery. More particularly, it concerns the use as perfuming ingredients of a 2,4-dialkyl-pyridine of formula (I): in the form of any one of its stereoisomers or a mixture thereof, wherein R1 represents a C1-3 alkyl group; R2 represents a C4-9 linear alkyl group; and the compound has between 10 and 15 carbon atoms. These compounds are useful for imparting odors of the green and/or pyrazine type. The present invention concerns the use of such compounds in the perfumery industry as well as the compositions or articles containing them.
US08652447B2	Cosmetic and personal care products containing synthetic magnesium alumino-silicate clays The invention provides for cosmetic and personal care compositions comprising a synthetic magnesium aluminosilicate clay. The synthetic magnesium aluminosilicate clay is formed at ambient pressure by a series of reaction steps and a pH change from acidic pH to basic pH. The characteristics of the magnesium aluminosilicate clay, including platelet size, degree of stacking, and porosity can be tuned depending on the cosmetic or personal care product desired. In addition, these cosmetic and personal care compositions optionally include one or more of the following components: odor controlling agents, skin protectants, diluents, lipophilic skin health benefit agents, sunscreens, humectants, emollients, slip compounds, and moisturizers.
US08652446B2	Apparatus and method for whitening teeth Disclosed herein is a pair of dry type patches for teeth whitening, having a patch for upper teeth and a patch for lower teeth, in which the patch for upper teeth has a shape different from the patch for lower teeth, and each patch has a controlled width and shape such that the contact area of each patch with gums is minimized. In the patch for upper teeth, a central portion covering right and left upper central incisors is widest. In the patch for lower teeth, either portion covering right and left lower canine teeth is widest. Since the dry type patches covers all the portions of the teeth while minimizing the contact area with gums, no or little irritation is caused and wearability is excellent.
US08652436B2	Material for water gas A material for water gas contains polyhydric alcohol, and hydroxycarboxylic acid.
US08652429B2	Oxidation catalyst for internal combustion engine exhaust gas treatment The invention provides an exhaust gas cleaning oxidation catalyst and in particular to an oxidation catalyst for cleaning the exhaust gas discharged from internal combustion engines of compression ignition type (particularly diesel engines). The invention further relates to a catalysed substrate monolith comprising an oxidizing catalyst on a substrate monolith for use in treating exhaust gas emitted from a lean-burn internal combustion engine. In particular, the invention relates to a catalysed substrate monolith comprising a first washcoat coating and a second washcoat coating, wherein the second washcoat coating is disposed in a layer above the first washcoat coating.
US08652427B2	Preparation and repeated regeneration of material containing amorphous iron oxide hydroxide, desulfurization agents containing the material, and preparation and repeated regeneration thereof Method for preparing material containing amorphous iron oxide hydroxide, the method including: mixing an aqueous ferrous salt solution and hydroxide solution or solid hydroxides at the temperature of below 70° C., filtering the reaction solution, washing the filter cake, preparing suspension solution of the filter cake, blowing an oxygen-containing gas into the suspension solution to oxidize the ferrous iron, and then filtering and drying. The material after being used as desulfurization agent can be repeatedly regenerated through oxidation in an oxygen-containing gas. A desulfurization agent, and methods for preparation and repeated regeneration thereof. The desulfurization agent contains the material and organic binders, and may also include a small amount of additives. The organic binders are selected from sodium carboxymethyl cellulose, sesbania powder, and cellulose powder, and the additives are selected from sawdust, rice husk power, and bran.
US08652426B2	Use of aqueous guanidinium formate solutions for the selective catalytic reduction of nitrogen oxides in exhaust gases of vehicles The invention relates to the use of aqueous guanidinium formiate solutions, optionally combined with urea and/or ammonia and/or ammonium salts, for the selective catalytic reduction of nitrogen oxides using ammonia in exhaust gases of vehicles. The inventive guanidinium formiate solutions enable a reduction of the nitrogen oxides by approximately 90%. Furthermore, said guanidinium formiate solutions can enable an increase in the ammonia forming potential from 0.2 kg, corresponding to prior art, up to 0.4 kg ammonia per liter of guanidinium formiate, along with freezing resistance (freezing point below −25° C.). The risk of corrosion of the inventive guanidinium formiate solutions is also significantly reduced compared to that of solutions containing ammonium formiate.
US08652423B2	Vial closure with septum retention feature A vial and closure assembly including a vial and a closure configured to be threadably coupled to the vial. The vial has an opening end that is defined by a vial rim and at least one thread located proximate to the open end of the vial. The closure includes a top wall with a skirt wall depending from the top wall. A septum pocket is provided in the top wall and is configured to receive a septum positioned therein. A protrusion depends from the top wall, extends into the septum pocket, and is configured to engage the septum so that the septum creates an essentially vapor-tight seal with the vial rim when the closure is threadably coupled to the vial.
US08652422B2	Immunoassay product and process The invention is directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.
US08652420B2	Device for the distribution of sample and carrier liquid across a micro-fabricated separation channel The present invention relates to a chromatographic separation device comprising a first substrate body carrying a micro-fabricated separation channel recessed on one of its surfaces and covered by a second substrate body, both perforated with connection-holes for the supply and withdrawal of a sample and carrier liquid. The present device is characterized in that said micro-fabricated separation channel is preceded or succeeded by a flow distribution region that is filled with an array of micro-fabricated pillars, having a shape, size and positioning pattern selected such that said flow distribution region has a ratio of transversal to axial permeability of at least 2.
US08652415B2	Method and apparatus for dispensing diagnostic test strips An apparatus for storing and dispensing a test strip includes a container configured to store a stack of test strips. The container maintains appropriate environmental conditions, such as humidity, for storing the test strips. An engaging member is disposed in the container and is adapted to contact one test strip of the stack of test strips. An actuator actuates the engaging member to dispense the one test strip from the container. Since one test strip is dispensed at a time, the remaining test strips are not handled by the user. Accordingly, the unused test strips remain free of contaminants such as naturally occurring oils on the user's hand.
US08652414B2	Device for sterilising containers A device for treating containers, with a housing, a sterilization chamber formed within the housing to sterilize the containers, with a transport device which transports the containers along a pre-specified transport path (P) through the sterilization chamber, and with at least one application device which applies a liquid sterilization medium to the containers during their transport through the sterilization chamber. The application device is integrated at least partly in a wall of the sterilization chamber.
US08652406B2	Blood processing unit with modified flow path A blood processing apparatus includes a heat exchanger and a gas exchanger. At least one of the heat exchanger and the gas exchanger is configured to impart a radial component to blow flow through the heat exchanger and/or gas exchanger. In some instances, the heat exchanger is configured to cause blood flow to follow a spiral flow path.
US08652400B2	Thermo-mechanical processing of nickel-base alloys A thermo-mechanical treatment process is disclosed. A nickel-base alloy workpiece is heated in a first heating step to a temperature greater than the M23C6 carbide solvus temperature of the nickel-base alloy. The nickel-base alloy workpiece is worked in a first working step to a reduction in area of 20% to 70%. The nickel-base alloy workpiece is at a temperature greater than the M23C6 carbide solvus temperature when the first working step begins. The nickel-base alloy workpiece is heated in a second working step to a temperature greater than 1700° F. (926° C.) and less than the M23C6 carbide solvus temperature of the nickel-base alloy. The nickel-base alloy workpiece is not permitted to cool to ambient temperature between completion of the first working step and the beginning of the second heating step. The nickel-base alloy workpiece is worked to a second reduction in area of 20% to 70%. The nickel-base alloy workpiece is at a temperature greater than 1700° F. (926° C.) and less than the M23C6 carbide solvus temperature of the nickel-base alloy when the second working step begins.
US08652397B2	Ultrasonic device with integrated gas delivery system Ultrasonic devices having an integrated gas delivery system are described, and these devices can be used to remove dissolved gasses and impurities from molten metals.
US08652395B2	Method for feeding pulverised coal into a blast furnace The present invention proposes a method for feeding pulverised coal into a blast furnace, wherein the method comprises the following steps: providing a tuyere stock (14) for blowing hot blast air from a bustle pipe (12) into a furnace hearth of a blast furnace through a tuyere (15) in an opening in the furnace wall (16); providing a pulverised coal injection lance (18) for feeding pulverised coal into the tuyere (15), the pulverised coal injection lance (18) comprising an inner pipe (20) for conveying pulverised coal and an outer pipe (22), coaxially arranged around the inner pipe (20), for conveying combustive gas, the inner pipe (20) forming a separation wall for separating the pulverised coal from the combustive gas, the pulverised coal injection lance (18) having a lance tip (24) arranged in the tuyere (15); allowing the pulverised coal and the combustive gas to form a mixture of pulverised coal and combustive gas at the lance tip (24); burning the mixture of pulverised coal and combustive gas in the tuyere (15); monitoring whether or not a flame at the lance tip (24) is burning; and upon determination that the flame at the lance tip (24) is not burning, reigniting the flame by temporarily reducing the flow of combustive gas through the pulverised coal injection lance (18).
US08652393B2	Strain and kinetics control during separation phase of imprint process Systems and methods for improving robust layer separation during the separation process of an imprint lithography process are described. Included are methods of matching strains between a substrate to be imprinted and the template, varying or modifying the forces applied to the template and/or the substrate during separation, or varying or modifying the kinetics of the separation process.
US08652389B2	Compression moulding method for realising thermoplastic products A method for realising thermoplastic products, comprising: use of a granular material comprising granules of thermoplastic polymers; inserting a dose (M) of the granular material internally of the chamber (11) of a mold (10); compression of the dose (M) of granular material contained in a chamber (11) of the mold (10); heating an internal surface of the chamber (11) of the mold (10) during the compression up to producing a softening of the thermoplastic granules at least of a most external layer of the dose (M) of granular material compressed in the chamber (11); before the stage of compression and heating, the method includes covering at least a portion of an external surface of the dose (M) of granular material with an opaque film, which film comprises at least an opaque portion such as visually to hide the material covered thereby.
US08652385B2	Method of manufacturing a decorative article with sealed decorative laminated sheet An eyeglass frame including a thermoplastic sheet laminate incorporating transfer printing eyeglass decorative patterns and a one or more covering layers bonded thereto. A process for manufacturing an eyeglass frame including: preparing a thermoplastic sheet laminate incorporating eyeglass decorative patterns; bending said thermoplastic sheet laminate under heat and pressure forming a one or more intermediate products in a first mold; and bonding a one or more covering layers to the intermediate products from the bending step in a second mold.
US08652382B2	Methods of joining Methods of joining members, forming molded portions with members, securing inserts with members, and joined members, such as for a frame or a frame for a fenestration unit, formed thereby, are disclosed. One embodiment of the method includes placing a first member with a first cavity in a joining position, placing a second member proximate the first cavity of the first member in the joining position, injecting a resin into the first cavity, allowing the resin to solidify at least partially to join the first member and second member to form a joined member, and removing the joined member from the joining position. Optionally, the joined member can be formed in a fixture, can include molded portions formed by the resin, and/or can include inserts held in place by the resin. Further, members without cavities can form a cavity that can receive the resin.
US08652379B2	Method and system for manufacturing hollow reinforced concrete modular elements and element obtained therefrom Method for manufacturing modular, hollow, prismatic, monolithic reinforced-concrete elements of rectangular section, which includes the stages of concreting their side walls in two horizontally arranged formwork structures, carrying out a rotation of said formwork structures so as to leave them arranged vertically on either side of a third formwork, with said third formwork horizontal, then concreting the floor slab, placing formwork between the side walls for concreting of the ceiling slab and withdrawing the modular element, so that a high degree of monolithism is achieved, a method in which all the concretings are carried out in the horizontal, and precise control is achieved over the measurements of the element obtained.
US08652377B2	Tubular free-shaped article The invention relates to a process for manufacturing of tubular free-shaped articles having an inner polymer layer and an outer polymer layer by co-extruding at least two different polymers in an extruder apparatus comprising an extrusion die and at least two extruder barrels/heads. The invention furthermore relates to a tubular free-shaped article comprising at least two layers of different polymers and which article is obtained by the process according to the invention.
US08652376B2	Process for producing nanostructured and/or microstructured surfaces in an adhesive layer, more particularly in a self-adhesive layer The invention relates to a process for producing nanostructured and/or microstructured surfaces in an adhesive layer, more particularly in a self-adhesive layer, in which an adhesive polymer mixture, more particularly a self-adhesive polymer mixture, is guided into a nip formed by a relief roll, whose surface has been provided with a relief which represents the negative of the surface structure to be produced on the adhesive layer, and by a nip roll, and where the relief roll and the nip roll rotate in opposite directions, wrapped partly around the relief roll is a web-form carrier material which is guided through the nip and whose speed corresponds more particularly to the peripheral speed of the relief roll, the adhesive polymer mixture, more particularly the self-adhesive polymer mixture, is pressed through the nip, so that the near-roll surface of the polymer mixture is shaped in accordance with the relief, lies in layer form on the carrier material after passage through the nip, and is guided away with the carrier material.
US08652370B2	Hot isostatic pressing method and apparatus A hot isostatic pressing method is disclosed wherein workpieces are accommodated within a high pressure vessel and the interior of the high pressure vessel is filled with an inert gas of a high temperature and a high pressure to treat the workpieces. The method includes a cooling step which is performed after maintaining the interior of the high pressure vessel at a high temperature and a high pressure for a predetermined time and in which a liquid inert gas is fed into the high pressure vessel. According to this method it is possible to shorten the cycle time of an HIP apparatus.
US08652368B2	Devices and methods for tissue engineering A resorbable tissue scaffold fabricated from bioactive glass fiber forms a rigid three-dimensional porous matrix having a bioactive composition. Porosity in the form of interconnected pore space is provided by the space between the bioactive glass fiber in the porous matrix. Strength of the bioresorbable matrix is provided by bioactive glass that fuses and bonds the bioactive glass fiber into the rigid three-dimensional matrix. The resorbable tissue scaffold supports tissue in-growth to provide osteoconductivity as a resorbable tissue scaffold, used for the repair of damaged and/or diseased bone tissue.
US08652365B2	Mold set and manufacturing method for manufacturing optical element A mold set includes: a first mold and a second mold placed so that they sandwich an optical material and face each other; and a first spacer and a second spacer provided between the first and second molds, wherein: the first spacer secures an interval between the first and second molds at a first temperature achieved in a process of pressurizing the optical material; the first spacer shrinks in a mold opening-closing direction more greatly than the second spacer while the first temperature is changing to a second temperature achieved in a process of cooling the optical material; and the second spacer secures the interval between the first and second molds at the second temperature.
US08652359B2	Red light-emitting fluorescent substance and light-emitting device employing the same The embodiment provides a red light-emitting fluorescent substance represented by the following formula (1): (M1-xECx)aM1bAlOcNd (1). In the formula (1), M is an element selected from the group consisting of IA group elements, IIA group elements, IIIA group elements, IIIB group elements, rare earth elements and IVA group elements; EC is an element selected from the group consisting of Eu, Ce, Mn, Tb, Yb, Dy, Sm, Tm, Pr, Nd, Pm, Ho, Er, Cr, Sn, Cu, Zn, As, Ag, Cd, Sb, Au, Hg, Tl, Pb, Bi and Fe; M1 is different from M and is selected from the group consisting of tetravalent elements; and x, a, b, c and d are numbers satisfying the conditions of 0
US08652358B2	Aluminum oxide phosphor and method for producing the same The present invention provides an Al—C—O based phosphor using neither heavy metal nor rare metal and composed of elements with high environmental compatibility and excellent economic efficiency, wherein the wavelength of the peak intensity of the emission spectrum can be changed without changing the basic composition. An aluminum oxide phosphor which comprises aluminum (Al), carbon (C), and oxygen (O) respectively in an amount of 30 mol %
US08652357B2	Phosphor, method for preparing and using the same, light emitting device package, surface light source apparatus and lighting apparatus using red phosphor Disclosed are a phosphor, a method for preparing and using the same, a light emitting device package, a surface light source apparatus, a lighting apparatus using the phosphor, and a display apparatus. The phosphor includes an inorganic compound represented by an empirical formula (Sr, M)2SiO4-xNy:Eu, where M is a metallic element, 0
US08652356B2	Blue phosphor, and light-emitting device using the same The blue phosphor of the present invention is represented by the general formula aBaO.bSrO.(1−a−b)EuO.cMgO.dAlO3/2.eWO3, where 0.70≦a≦0.95, 0≦b≦0.15, 0.95≦c≦1.15, 9.00≦d≦11.00, 0.001≦e≦0.200, and a+b≦0.97 are satisfied. In the blue phosphor of the present invention, two peaks whose tops are located in a range of diffraction angle 2θ=13.0 to 13.6 degrees and one peak whose top is located in a range of diffraction angle 2θ=14.6 to 14.8 degrees are present in an X-ray diffraction pattern obtained by measurement on the blue phosphor using an X-ray with a wavelength of 0.774 Å.
US08652352B2	Photoresponsive nanoparticles as light-driven nanoscale actuators Photoresponsive shape memory nanoparticles have a layered smectic ordering and include a photoresponsive moiety selected from the group consisting of azobenzene, stilbene, and spiropyran. Multiple cycles of contraction and extension in these materials can be controlled by UV and visible light. By changing light intensity and exposure time, the magnitude of actuation can be modulated.
US08652351B2	Titanic acid compound, process for producing the titanic acid compound, electrode active material containing the titanic acid compound, and storage device using the electrode active material This invention provides a titanic acid compound-type electrode active material having a high battery capacity and, at the same time, having excellent cycle characteristics. The titanic acid compound exhibits an X-ray diffraction pattern corresponding to a bronze-type titanium dioxide except for a peak for a (200) plane and having a peak intensity ratio between the (001) plane and the (200) plane, i.e., I(200)/I(001), of not more than 0.2. The titanic acid compound may be produced by heat dehydrating H2Ti3O7 at a temperature in the range of 200 to 330° C., by heat dehydrating H2Ti4O9 at a temperature in the range of 250 to 650° C., or by heat dehydrating H2Ti5O11 at a temperature in the range of 200 to 600° C.
US08652350B2	Chemical mechanical polishing aqueous dispersion, chemical mechanical polishing method using the same, and method of recycling chemical mechanical polishing aqueous dispersion A chemical mechanical polishing aqueous dispersion includes (A) abrasive grains, (B) an organic acid, and (C1) copper ions or (C2) at least one kind of metal atoms selected from Ta, Ti, and Rb, the chemical mechanical polishing aqueous dispersion including the copper ions (C1) at a concentration of 1×101 to 2×105 ppm, or including the at least one kind of metal atoms (C2) selected from Ta, Ti, and Rb at a concentration of 1×10−1 to 1×103 ppm.
US08652345B2	Method of forming a patterned substrate A method of forming a patterned substrate is provided. The method includes providing a substrate (300) having a structured surface region comprising one or more recessed features (310). The method includes disposing a first liquid (325) onto at least a portion of the structured surface region. The method includes contacting the first liquid with a second liquid (330). The method includes displacing the first liquid with the second liquid from at least a portion (315) of the structured surface region. The first liquid is selectively located in at least a portion of the one or more recessed features.
US08652343B2	Method for selectively removing material from the surface of a substrate, masking material for a wafer, and wafer with masking material A method for the selective removal of material from a substrate surface for forming a deepening includes the steps of applying a mask onto the substrate surface in accordance with the desired selective removal and dry-etching the substrate, a metal, preferably aluminum, being used as the masking material. Power may be coupled inductively to a plasma.
US08652335B2	Scavenger supports and the use thereof in a process for the extraction of metals A scavenger support and a process for removing metal from solution by contacting the solution with the scavenger support, whereby the scavenger support binds to at least some of the metal in solution thereby decreasing the amount of metal in solution. The scavenger support is a functionalised support having pendant groups selected from 1,3-ketoesters or 1,3-ketoamides or mixtures thereof having a structure according to formula 1, wherein a number of the pendant groups are reacted with an amine: wherein R1 is an optionally substituted hydrocarbyl, perhalogenated hydrocarbyl or heterocyclyl group; X is O or NR2, wherein the free valence of O or NR2 is bonded to a support optionally via a linker; and R2 is hydrogen, an optionally substituted hydrocarbyl, or heterocyclyl group.
US08652329B2	Sewage nitrate removal by free-draining asphyxiant filtration and carbon addition In a sewage disposal system, a de-nitrification station is configured as a heap of foam cubes located in an airtight enclosure from which oxygen is excluded. Carbon is added to the incoming nitrified water. The heap of foam cubes is arranged as a free-draining trickle filter, but here under asphyxiant conditions in the enclosure. Anaerobic microbiological reactions reduce the nitrate to nitrogen gas. Effluent from the de-nitrifier is polished by feeding back a fraction of the effluent through the aeration station from which the nitrate water is derived, or a separate polishing station can be provided.
US08652325B2	Device and method for cleaning up spilled oil and other liquids A device for cleaning up spilled oil from the surface of a body of water, including a vessel adapted to float on the body of water and to pass over the oil, wherein the vessel has an inclined bow surface for directing the oil downwardly beneath the vessel. The device includes an oil/water separation column carried on the vessel having an inner cavity with a lower end forming a bottom opening oriented substantially parallel to the surface of the body of water in fluid communication with the water and spilled oil such that oil directed downwardly beneath the vessel by the bow surface is directed to the bottom opening. At least a substantial portion of the oil/water separation column is narrowed with increasing height beginning at least at a height approximately corresponding to the water line. The device further includes at least a pump in sealed engagement with an upper end portion of the oil/water separation column, the at least a pump for drawing water and the spilled oil into the oil/water separation column and for drawing the spilled oil from the oil/water separation column.
US08652321B2	Process for the production of a desulfurized gasoline from a gasoline fraction that contains conversion gasoline Production of gasolines with low sulfur contents from a starting gasoline containing sulfur-containing compounds comprising a stage a) for selective hydrogenation of non-aromatic polyunsaturated compounds present in the starting gasoline, a stage b) for increasing the molecular weight of the light sulfur-containing products that are initially present in the gasoline that enters this stage, a stage c) for alkylation of at least a portion of the sulfur-containing compounds present in the product that originates from stage b), a stage d) for fractionation of the gasoline that originates from stage c) into at least two fractions, one fraction virtually lacking in sulfur-containing compounds, whereby the other contains a larger proportion of sulfur-containing compounds (heavy gasoline), a stage e) for catalytic treatment of the heavy gasoline for transformation of sulfur-containing compounds under conditions for the at least partial decomposition of hydrogenation of these sulfur-containing compounds.
US08652320B2	Biosensors and methods of preparing same A biosensor strip having a low profile for reducing the volume of liquid sample needed to perform an assay. In one embodiment, the biosensor strip includes an electrode support; an electrode arrangement on the electrode support; a cover; a sample chamber; and an incompressible element placed between the cover and the electrode support, the incompressible element providing an opening in at least one side or in the distal end of the sample chamber to provide at least one vent in the sample chamber. In another embodiment, the biosensor strip has an electrode support; an electrode arrangement on the electrode support; a cover; and a sample chamber, the cover having a plurality of openings formed therein, at least one of the openings in register with the sample chamber. The invention further includes methods for preparing such a biosensor strips in a continuous manner.
US08652317B2	Method of fabricating an alumina nanohole array, and method of manufacturing a magnetic recording medium An alumina nanohole array and a method of fabricating the same includes the steps of forming an aluminum thin-film on a substrate at a substrate temperature of −80° C. or below so that crystal grain growth is suppressed, even when a high-purity aluminum material is used, thus providing improved surface smoothness; and anodizing the aluminum thin-film. Preferably, the method additionally includes texturing by pressing a mold having an orderly array of projections against the aluminum thin-film to form pits on the aluminum thin-film which enables a larger array area to be formed. When the mold and the aluminum thin-film are held at a temperature of 150 to 200° C., the pressure used for pit formation is reduced. A magnetic recording medium manufactured by a method therefore includes forming a magnetic layer within the nanoholes so that the medium is suitable as a bit patterned media for a perpendicular recording system.
US08652307B2	Apparatus and method for magnetic field assisted electrochemical discharge machining In an apparatus and method for magnetic field assisted electrochemical discharge machining (ECDM), the magneto hydrodynamic (MHD) effect is utilized to improve the thickness of bubble film and the electrolyte circulation so as to enhance the machining accuracy and efficiency. Since charged ions in a magnetic field are induced by Lorenz force to move, and the electrolysis bubbles generated in the ECDM process are suffused with electrification ions on their surfaces, the electrolysis bubbles can be forced to move in the direction of the magnetic field without the need of mechanical disturbance. The present invention can be widely applied in the micro-machining of non-conductive brittle materials of different dimensions and shapes, comprising the forming of microchannels and microholes on a biochip, and in the micro-opto-electro-mechanical system (MOEMS) and various kinds of micro-machining fields. The machined surface is smooth and does not require a second time machining.
US08652302B2	Fabric belt for a machine for the production of web material, particularly paper or cardboard A fabric belt for a machine for producing a web of fibrous material includes: a first fabric layer including a web contact side and formed by interweaving a plurality of warps with a plurality of wefts; and a second fabric layer positioned below said first fabric layer and formed by interweaving a plurality of warps with a plurality of wefts, a first ratio of a number of said plurality of warps of said first fabric layer to a number of said plurality of warps of said second fabric layer being greater than 1, a second ratio of a number of said plurality of wefts of said first fabric layer to a number of said plurality of wefts of said second fabric layer being greater than 1.
US08652300B2	Methods of making a belt-creped absorbent cellulosic sheet prepared with a perforated polymeric belt A method of making a belt-creped absorbent cellulosic sheet. A paper making furnish is compactively dewatered to form a dewatered web having an apparently random distribution of papermaking fiber orientation. The dewatered web is applied to a translating transfer surface that is moving at a transfer surface speed. The web is belt-creped from the transfer surface at a consistency of from about 30% to about 60% utilizing a generally planar polymeric creping belt having a plurality of perforations, under pressure, in a belt creping nip defined between the transfer surface and the creping belt. The belt travels at a belt speed that is slower than the speed of the transfer surface. The web is creped from the transfer surface and redistributed on the creping belt to form a web having a plurality of interconnected regions of different local basis weights. The web is then dried.
US08652299B2	Welding of PTFE parts During the joining of PTFE parts (10), a binder (20) is applied to the joint surfaces of the PTFE parts, e.g. by welding, before the parts are joined. By establishing a bond between PTFE and binder in a separate, initial process, the parameters of this initial process may be determined regardless of other conditions, such as maintaining the dimensions, and the quality of this bond may be controlled and approved before the subsequent joining of the PTFE parts. During the subsequent joining, the temperature may be kept at a level, which is sufficiently low so as not to deform the PTFE material permanently, or the joining may be carried out by a process, which does not require heating, for example gluing.
US08652298B2	Triode reactor design with multiple radiofrequency powers Methods, systems, and computer programs are presented for semiconductor manufacturing are provided. One wafer processing apparatus includes: a top electrode; a bottom electrode; a first radio frequency (RF) power source; a second RF power source; a third RF power source; a fourth RF power source; and a switch. The first, second, and third power sources are coupled to the bottom electrode. Further, the switch is operable to be in one of a first position or a second position, where the first position causes the top electrode to be connected to ground, and the second position causes the top electrode to be connected to the fourth RF power source.
US08652288B2	Reinforced acoustical material having high strength, high modulus properties A multilayer composite material is formed of an acoustic core layer and at least one outer strengthening layer. The acoustic composite material has desirable high strength and high flexural modulus properties.
US08652286B2	Stretchable applique and method for making the same A stretchable appliqué made from a stretchable substrate with indicia thereon may be applied to a variety of articles including stretchable performance athletic wear. A method for making the stretchable appliqué may include applying an adhesive and a carrier layer to one surface of a stretchable substrate. Indicia may then be applied to the opposite surface of the stretchable fabric and the stretchable substrate may be cut to a desired shape to form the stretchable appliqué. The carrier layer may then be removed and the stretchable appliqué may be adhered to the desired article. The stretchable appliqué may be adhered to stretchable articles of apparel so that the appliqué may stretch when the article of apparel stretches. The carrier layer may be less stretchable than the stretchable substrate, including being completely non-stretchable.
US08652280B2	Apparatus, system, and method for medical structure embellishments An apparatus, system, and method are disclosed for medical structure embellishments. The apparatus includes a medical structure that facilitates the mobility or healing of a patient. The apparatus also includes a heat source that outwardly radiates heat. Further, the apparatus includes a shrink-film structure cover that shrinks around a surface of the medical structure when the shrink-film structure cover is exposed to heat radiated from the heat source and a marking instrument adapted to mark the shrink-film structure with an embellishment.
US08652279B2	Method for producing sandwich components and corresponding press The invention relates to a method for the production of sandwich components with an open core structure and a cover layer applied to each side, wherein the cover layers are formed with a curable plastic material, and the sandwich component is cured in a closed device under pressure. A charging gas, which may be nitrogen or air, is introduced to the core structure prior to at least partial solidification of the cover layers, wherein a charging gas pressure p Charging gas is selected that is less than or equal to an operating pressure p operating of the closed device in order to, in particular, at least largely prevent the formation of sink marks in the cover layers. Furthermore, the invention relates to a press for implementing the method.
US08652277B2	Weakly oxidizing ammonium nitrate composite materials and methods for preparing such compositions A method forms a relatively stable ammonium nitrate composite material. The method includes (a) blending ammonium nitrate with an average particle diameter greater than about 1 mm and a substantially non-oxidizing compound in fine particle form; and (b) reducing the average size of said ammonium nitrate granules in the presence of the non-oxidizing compound in fine particle form to produce a substantially homogeneous blend of ammonium nitrate and the non-oxidizing compound having an average particle diameter of about 1 to about 1,000 μm to form a substantially non-explosive powder.
US08652269B2	Flux composition and soldering paste composition Disclosed herein are a flux and a soldering paste based on the flux. The flux is free from a change in viscosity with age, “skinned surface,” and “rough and crumbling,” and is excellent in printability and solderability. The flux contains, as elements, a resin, a thixo agent, an activator, a solvent and glucopyranosylamine type nanotube. The soldering paste further contains a solder powder. Preferably, the solder powder is free from lead.
US08652268B2	Substrate treating method for treating substrates with treating liquids A method for treating substrates with treating liquids, using a treating tank for storing the treating liquids, a holding mechanism for holding the substrates in a treating position inside the treating tank, first and second treating liquid supply devices, a temperature control device, and a control device. A first treating liquid is supplied into the treating tank, then a second treating liquid of lower surface tension and higher boiling point than the first treating liquid is supplied, and placed in a temperature range above the boiling point of the first treating liquid and below the boiling point of the second treating liquid. Then the second treating liquid supply device may be controlled to replace the first treating liquid with the second treating liquid, while controlling the temperature control device to maintain the second treating liquid in the same temperature range.
US08652266B2	Method and apparatus for surface treatment of semiconductor substrates using sequential chemical applications A system and method for removing polymer residue from around a metal gate structure formed on a surface of a substrate during a post-etch cleaning operation includes determining a plurality of process parameters associated with the metal gate structure and the polymer residue to be removed. A plurality of fabrication layers define the metal gate structure and the process parameters define characteristics of the fabrication layers and the polymer residue. A first cleaning chemistry and second cleaning chemistry are identified and a plurality of application parameters associated with the first and second cleaning chemistries are defined based on the process parameters. The first and second application chemistries are applied sequentially in a controlled manner using the application parameters to substantial remove the polymer residue while preserving the structural integrity of the gate structure.
US08652265B2	Method for cleaning heat exchanger tube bundles An improved method for cleaning heat exchange tube bundles, fin-fans, and other elongated components, using a portable cleaning system comprising a cleaning unit having a cleaning enclosure that receives and cleans the component and a control unit that controls the operation of the system. The cleaning unit has a cleaning enclosure defining a chamber sized and configured to receive the component through a sealable lid. A roller assembly rotates the component while a spray assembly sprays cleaning fluid over and into the rotating component. The cleaning fluid is heated in the chamber using surface heating elements attached to heat transfer plates along sections of the chamber walls. A vapor recovery system captures and treats toxic vapors. In use, the cleaning system is transported to a facility to clean the components on-site using cleaning fluid supplied by the facility and discharging waste to the facility.
US08652264B2	Rear washer fluid enable/disable A method and apparatus for preventing the dispensing of a washer fluid onto a rear windshield upon detecting the disablement of the rear wiper arm is provided. The disablement of the rear wiper arm may be caused by the movement of the rear windshield from a fully closed position to an open position.
US08652261B2	Process for dissolving cellulose-containing biomass material in an ionic liquid medium A process is disclosed for dissolving the cellulose component if a cellulose-containing biomass material in an Ionic Liquid medium. The biomass material contains minerals. At least part of the minerals are removed prior to contacting the biomass material with the Ionic Liquid medium. The Ionic Liquid medium preferably is an inorganic molten salt hydrate.
US08652260B2	Apparatus for holding semiconductor wafers Apparatus for holding semiconductor wafers during semiconductor manufacturing processes are disclosed. In one embodiment, the apparatus comprises a heat-conductive layer disposed on a supporting base. The apparatus also comprises a plurality of holes formed through the heat-conductive layer and the supporting base. The apparatus further comprises a plurality of heat-conductive lift pins that extend through the holes over the heat-conductive layer at the top end, and make a direct contact with a wafer substrate. The heat-conductive layer and the lift pins are connected to a heating circuit.
US08652257B2	Controlled gravity feeding czochralski apparatus with on the way melting raw material A melting furnace, mounted adjacent a growth furnace, comprises a receiving container for melting therein raw material in a particle or powder form falling in it from a feeder. The receiving container accommodates a set of slope-wise plates providing a distributed sliding of partially melted raw material particles over the surface of these plates and their complete melting while moving downward; eventually the melted raw material flows into the crucible of the growth furnace through a conveying tube extending slantingly from the bottom of the receiving container to the crucible through coaxial openings in housings of both furnaces. The rate of feeding is given solely by the feeder, and at continuous feeding the raw material flows continuously by gravity from the feeder to the crucible of the growth furnace, first in a solid state (powder, granules, pellets, etc.) and then in a liquid state.
US08652256B2	Manufacturing apparatus of polycrystalline silicon A manufacturing apparatus of polycrystalline silicon products polycrystalline silicon by depositing on a surface of a silicon seed rod by supplying raw-material gas to the heated silicon seed rod provided vertically in a reactor, includes: an electrode which holds the silicon seed rod and is made of carbon; an electrode holder which holds the electrode, and cooled by coolant medium flowing therein, wherein the electrode includes: a seed rod holding member which holds the silicon seed rod; a heat cap which is provided between the seed rod holding member and the electrode holder; and a cap protector having a ring-like plate shape, which covers an upper surface of the heat cap, and in which a through hole penetrating the lower-end portion of the seed rod holding member is formed.
US08652254B2	Method for pulling silicon single crystal The invention is a method for pulling a silicon single crystal, which is a Czochralski method for growing the silicon single crystal by contacting a seed crystal with a melt and by pulling up, including the steps of: contacting the seed crystal with the melt; forming a necking portion under the seed crystal; and forming the silicon single crystal under the necking portion by increasing a diameter, wherein a pulling rate during forming the necking portion is 2 mm/min or less, and the silicon single crystal with the increased diameter is a boron-doped silicon single crystal having a resistivity of 1.5 mΩ·cm or less at a shoulder portion. Therefore, there can be provided a method of pulling a silicon single crystal without generating defects such as scratches at a wafer surface in the case of processing a boron-doped silicon single crystal ingot with a low resistivity produced by CZ method into a wafer.
US08652251B2	Sulfur steel-slag aggregate concrete A sulfur-steel slag aggregate concrete, and methods of preparing the sulfur-steel slag aggregate concrete and disposing of elemental sulfur, are disclosed. In embodiments, the sulfur-steel slag aggregate concrete includes elemental sulfur, steel slag aggregate, limestone powder, and sand. Modifiers, such as plasticizers, are not required and are not used in embodiments of the sulfur-sand limestone mortar. In embodiments of the method to prepare the sulfur-steel slag aggregate concrete, each of the elemental sulfur, limestone powder, steel-slag, and sand are heated to at least 140 C, then combined, and then allowed to solidify.
US08652249B2	Amine sacrificial agents and methods and products using same A method of producing cementitious mixtures containing fly ash as one of the cementitious components, under air entrainment conditions is described. The method involves forming a mixture comprising water, cement, fly ash, optionally other cementitious materials, aggregate, conventional chemical admixtures, and an air entrainment agent and agitating the mixture to entrain air therein. Additionally, at least one amine sacrificial agent is included in the mixture. The cementitious mixtures and hardened concretes resulting from the method and fly ash treated with sacrificial agent, or air entrainment agent/sacrificial agent combinations, are also described.
US08652246B2	Composition containing an organic fraction for making a road or building layer and/or coating A viscous composition for making a layer and/or a coating for a road track or a building, and containing a viscous fraction. The viscous fraction mainly contains vegetable pitch, in particular tall oil pitch, and a phenolic modified rosin.
US08652245B2	Dual color electronically addressable ink A dual color electronically addressable ink includes a non-polar carrier fluid; a first colorant of a first color; and a second colorant of a second color that is different than the first color. The first colorant includes a first particle core, and a first functional group attached to a surface of the particle core. The first functional group is capable of carrying a positive charge and is chosen from a base or a salt of the base. The second colorant includes a particle core, and a second functional group attached to a surface of the particle core. The second functional group is capable of carrying a negative charge and is chosen from an acid or a salt of the acid. The ink further includes an additive chosen from polyhydroxystearic amide salt, polyhydroxystearic acid, aromatic butyric acid, and combinations thereof.
US08652242B2	Dust collection device A dust collection device includes a machine body that forms an air chamber and a chassis arranged below the machine body. The chassis receives therein a dust collection tank. A mechanics case that contains a motor and blower assembly is arranged at one side of the machine body. The mechanics case includes a partition board to divide the mechanics case into an inlet flow channel communicating the air chamber and an outlet flow channel for discharging air. The partition board forms an air vent hole in communication with the outlet flow channel. A block unit is provided on the partition board and includes a block plate that selectively blocks the air vent hole. When a fire occurs inside the air chamber, the partition board prevents the fire flame from being drawn into the mechanics case, and the block plate timely blocks the air vent hole to improve operation safety.
US08652240B2	Fine particle sensor and mounting structure therefor There is provided a fine particle sensor for detecting fine particles in exhaust gas, including an ion generating unit for generating ions by corona discharge, a charging unit for charging the fine particles by some of the generated ions, an ion trapping unit for trapping a remainder of the generated ions and a casing for accommodating therein the charging unit and the ion trapping unit in a given arrangement direction. The casing has a gas inlet hole and a gas outlet hole formed in a circumferential wall thereof so that the exhaust gas flows in the charging unit through the gas inlet hole and flows out of the ion trapping unit through the gas outlet hole. The gas inlet hole and the gas outlet hole are arranged in such a manner as to at least partially overlap each other when viewed in the given arrangement direction.
US08652235B2	Sorbents for the oxidation and removal of mercury A promoted carbon and/or non-carbon base sorbent are described that are highly effective for the removal of mercury from flue gas streams. The promoted sorbent comprises a carbon and/or non-carbon base sorbent that has reacted with and contains forms of halogen and halides. Optional components may be added to increase and/or preserve reactivity and mercury capacity. These may be added directly with the base sorbent, or in-flight within a gas stream (air, flue gas, etc.), to enhance base sorbent performance and/or mercury capture. Mercury removal efficiencies obtained exceed conventional methods. The promoted sorbent can be regenerated and reused. Base sorbent treatment and preparation methods are also described. Methods for in-flight preparation, introduction, and control of the active base sorbent into the mercury contaminated gas stream are described.
US08652233B2	On-board hydraulic fluid degasification system for a hydraulic hybrid vehicle A fluid degasification system for a hydraulic circuit includes a gas/fluid separation tank, a fluid entry passage directing fluid into a small foam generating cup containing foam and a small amount of additional fluid, thereby stimulating foam formation. A separation screen is positioned below the foam generating cup to receive bubbles formed in the cup and to allow liquid to pass through the screen to a degasified-fluid collecting chamber below the screen as the bubbles resting on the separation screen decompose.
US08652232B2	Process for synthesizing cubic metallic nanoparticles in the presence of two reducing agents A process is described for preparing cubic metallic nanoparticles, comprising: a) preparing an aqueous solution containing a source of a metal from group VIII, a reducing agent R1 and a stabilizer; b) preparing an aqueous solution containing a source of a group VIII metal and a stabilizer at a temperature strictly higher than 70° C. and less than or equal to 80° C.; c) mixing at least a portion of the aqueous solution obtained in step a) with the aqueous solution obtained in step b) to obtain, in the presence of a reducing agent R2, metallic nanoparticles in the cubic form representing at least 70% by number of the entire quantity of metallic nanoparticles which are formed; d) depositing said metallic nanoparticles derived from step c) on a support.
US08652230B2	Media for hot gas filtration A filter fabric having improved filtering properties for hot gas filtration containing a nonwoven aramid mat The mat has a basis weight of at least 9.7 ounces per square yard (330 grams per square meter) and is characterized by a pore size distribution in which the number of pores in a given range as measured by ASTM F316-03 test method is plotted against pore size. In a preferred embodiment, the percentage of pores having a size in between 10 and 26 microns is greater than 50% while the percentage of pores having a size of greater than 50 microns is less than 0.5%.
US08652228B2	Filter elements; air cleaner; assembly; and, methods A filter element, a safety element and fluid cleaner assembly. The fluid cleaner assembly generally includes a housing having a cover and a primary fluid cleaner section. The element generally comprises z-filter media, arranged in a straight through configuration, and an axial seal gasket positioned to extend continuously around at outer perimeter of the straight through flow construction. The fluid cleaner assembly can have a precleaner positioned therein. Methods of assembly and use are provided.
US08652225B2	Flexible coated abrasive finishing article and method of manufacturing the same A flexible abrasive finishing article including a backing of fabric or paper having first and second major surfaces with abrasive particles adhesively secured to said first major surface and a layer of cyanoacrylate based material substantially covering the second major surface. The method of making a flexible abrasive finishing material including the steps of applying a layer of cyanoacrylate based material to a surface of a backing material opposite the surface to which abrasive particles are adhesively secured and covering said cyanoacrylate material.
US08652224B2	Hydrogen generator, fuel cell system and their operating methods A hydrogen generator (4) includes: a reformer (5) which is supplied with a raw material to generate a hydrogen-containing gas through a reforming reaction; a first gas supplying unit (1) which supplies a gas containing a nitrogen-containing compound to the reformer; a CO remover (7) which has an oxidation catalyst containing a metal to be poisoned by ammonia and uses the oxidation catalyst and an oxidation gas to remove carbon monoxide in the hydrogen-containing gas through an oxidation; a second gas supplying unit (3) which supplies the oxidation gas to the CO remover; and a control unit (10), wherein the gas containing the nitrogen-containing compound is supplied from the first gas supplying unit to the reformer during the reforming reaction, a fuel cell system (100) includes the hydrogen generator (4), and the control unit is configured to control to carry out a regeneration operation of the oxidation catalyst if a parameter regarding a cumulative amount of ammonia supplied to the CO remover has reached a predetermined threshold or more.
US08652221B2	Hybrid wax compositions for use in compression molded wax articles such as candles A hybrid wax compositions that are suitable for use in manufacturing wax articles (e.g., candles) by compression molding. The combination of a hydrogenated natural oil-based wax and a paraffin wax having a select distribution of hydrocarbon chain lengths provides the hybrid wax compositions with improved properties, such as improved compressive strength and improved de-molding characteristics, for example, as evidenced by reducing scarring and/or flashing. The hybrid wax compositions comprise: (a) a wax comprising a hydrogenated natural oil; and (b) a paraffin wax, wherein the paraffin wax comprises less than about 50% by weight of the hybrid wax composition, and wherein about 52% or greater of hydrocarbons in the paraffin wax have carbon chain lengths ranging from C25 to C29.
US08652220B2	Battery and related method A battery is provided with a plurality of unit cells each having a tab, a bus bar connecting the tab of one of the plurality of unit cells and the tab of another one of the plurality of unit cells, and a plurality of welding points disposed on a center of gravity of an area, in which the bus bar and the tab are overlapped, or a vicinity thereof, and at least one position of line segments, radiately extending from the center of gravity, or a vicinity thereof, such that the bus bar and the tab are connected to one another at the plurality of welding points.
US08652219B1	Powdered dye material for concrete surfaces The invention herein provides for an improved dye material composed of a dry particulate mixture of azo and phthalocyanine dyes for concrete surface applications.
US08652218B2	Powered leg prosthesis and control methodologies for obtaining near normal gait A powered leg prosthesis includes powered knee joint comprising a knee joint and a knee motor unit for delivering power to the knee joint. The prosthesis also includes a prosthetic lower leg having a socket interface coupled to the knee joint and a powered ankle joint coupled to the lower leg opposite the knee joint comprising an ankle joint and an ankle motor unit to deliver power to the ankle joint. The prosthesis further includes a prosthetic foot coupled to the ankle joint, at least one sensor for measuring a real-time input, and at least one controller for controlling movement of the prosthesis based on the real-time input.
US08652213B2	Aspheric hip bearing couple A joint prosthesis device comprises a head configured to fit within a cup and in one embodiment includes a first member for attachment to a first bone in a joint and including a first articulation surface portion defined by a first radius of curvature and a second member for attachment to a second bone in the joint and including a second articulation surface portion defined by a second radius of curvature and a third articulation surface defined by a third radius of curvature, wherein each of the second radius of curvature and the third radius of curvature has a length that is different from the length of the first radius of curvature by less than 0.05 millimeters and wherein the origin of the second radius of curvature is not coincident with the origin of the third radius of curvature.
US08652211B1	Modular toe joint implant Modular toe joint implant is a multi-piece device. Various sized piece(s), for example, head(s) and stem(s), can be provided in a kit or separately.
US08652205B2	Phase-shifted center-distance diffractive design for ocular implant A diffractive multifocal design for ocular implant is provided. This ocular implant includes a diffractive multifocal intraocular lens (IOL) and a number of haptics. The diffractive multifocal IOL passes optical energy to distance, intermediate and near foci. The haptics mechanically couple to the diffractive multifocal IOL in order to position and secure the diffractive multifocal IOL within the eye. The diffractive multifocal IOL may include both a diffractive region and a refractive region, the diffractive multifocal IOL operable to phase shift optical energy such that constructive interference occurs within the diffractive region and the refractive region.
US08652204B2	Transcatheter valve with torsion spring fixation and related systems and methods Described is a prosthetic valve, comprising: an expandable stent including an inner lumen and having a first and a second end; and a spring attached to the first end of the expandable stent; wherein the expandable stent and the spring can expand radially to a desired diametric configuration in order to anchor the prosthetic valve at an implantation position in a body lumen. Related systems and methods.
US08652201B2	Apparatus and method for treating cardiovascular diseases A method is provided for treating a cardiovascular disease, such as pulmonary arterial hypertension, an arrhythmia, or heart failure. One step of the method includes providing an apparatus. The apparatus includes an expandable support member having oppositely disposed proximal and distal end portions and a main body portion extending between the end portions. The proximal end portion includes a plurality of wing members extending from the main body portion. At least a portion of the expandable support member is treated with at least one therapeutic agent for eluting into a blood vessel. The expandable support member is inserted into the pulmonary vasculature and then advanced to a bifurcation in the pulmonary vasculature. The bifurcation includes the intersection of a first pulmonary vessel, a second pulmonary vessel, and a third pulmonary vessel. The expandable support member is secured at the bifurcation to treat pulmonary arterial hypertension, for example.
US08652199B2	Stent with autonomic function To provide a stent which holds various performances such as deliverability, prevention of restenosis, flexible shape conformability, and so on and is therefore adaptable not only to a bile duct but also to a blood vessel system such as a tortuous coronary artery substantially without causing restenosis. A stent with an autonomic function is made of a Ti—Ni based shape memory alloy and has a maximum expanding force at a center portion in its lengthwise direction.
US08652194B1	Method and apparatus for treating vulnerable plaque An apparatus and method to treat vulnerable plaque. In one embodiment, the apparatus has a medical device to treat an occlusive plaque, and is also adapted to release a biologically active agent to treat vulnerable plaque located downstream from the occlusive plaque. In an alternative embodiment, the apparatus has an expandable tube attached to the inner surface of a stent, and a layer of endothelial cells seeded on the inner surface of the expandable tube. The expandable tube shields a vulnerable plaque from a body lumen.
US08652191B2	Tubular graft construct Described are medical devices which are or can be used to form tubular medical devices, and related methods. Preferred devices include tubular grafts of biomaterial having lumen walls which present no seam edge that traverses the entire length of the lumen, illustratively including devices having lumen walls which have a discontinuous seam presenting multiple seam edges. Such a device may include a tubular structure formed by inserting a plurality of extensions of a biomaterial sheet through a plurality of corresponding apertures of the sheet.
US08652190B2	Heat exchange catheter apparatus and method for manipulating patient's body temperature A balloon catheter is used in a closed-loop heat exchange system for manipulating the temperature of a patient. The balloon catheter is positioned in the stomach of the patient, and then expanded with a heat exchange fluid delivered through a lumen formed in the shaft of the catheter. The balloon catheter comes into contact with the wall of the stomach, and the stomach substantially conforms around the expanded balloon catheter. The heat exchange fluid is allowed to flow continuously into and out of the balloon catheter. Heat is exchanged between the balloon catheter and the stomach so as to controllably alter the temperature of at least a portion of the patient. Anti-shivering mechanisms and automatic control based on temperature feedback from the patient may be used in connection with the heat exchange system.
US08652186B2	System and method for selecting follicular units for harvesting A system and method is provided for improving the visibility of hair on the skin surface, in a region that is bloodied or bruised, and potentially expanding the candidate pool of the hair grafts to be selected for harvesting. The system uses a light source comprising at least two emitters and the method comprises controlling the contrast between the image of the blood and the image of the skin surface. The method of the present invention may be implemented with various hair harvesting and transplantation systems, including manual, partially automated and fully automated systems.
US08652185B2	Apparatus for stimulating the brain and measuring the light induced neuronal activity and method for manufacturing the same Disclosed is an apparatus for stimulating the brain and measuring the light induced neuronal activity including a signal application unit which applies a signal to a living tissue to stimulate the neuronal cells in the living tissue; an electrode unit which detects an electrophysiological signal of the neuronal cell in response to the signal; and an insulation unit which controls an impedance of the electrode unit. The signal application unit is formed integrally with the electrode unit, so that the site where the signal is applied to the living tissue is approximated to the site where the response to the stimulation is measured.
US08652181B2	Cervical plate Screw back out prevention devices to inhibit screws from reverse threading or backing out are provided. The devices include first bonding materials on either a bushing in a bore of a plate or directly on the bore and second bonding materials on the screw head. The bonding materials for a bond that inhibits back out or reverse threading of the screw.
US08652180B2	Handle assembly having a radiopaque region to facilitate positioning a bone plate on bone Bone fixation system, including methods, apparatus, and kits, and comprising a bone plate and at least one instrument that attaches to the bone plate and provides at least one radiopaque region to facilitate positioning the bone plate on bone visualized by radiographic imaging. The instrument may be a handle assembly and/or a targeting guide.
US08652176B2	Polyaxial screw connection assembly A polyaxial screw connection assembly includes a first longitudinal member comprising a bored fastener channel and a first bulbous body; a second longitudinal member comprising a cylindrical body to fit within the fastener channel, and a second bulbous body; a fastener with a bored cylindrical channel, connected to the first longitudinal member and the cylindrical body and securely couples the first longitudinal member to the second longitudinal member; a first fixation component directly connected to the first bulbous body; a second fixation component directly connected to the second bulbous body; a first pin engaged within the first longitudinal member via a bored first channel and contacting the first bulbous body causing the first bulbous body to outwardly expand; and a second pin engaged within the second longitudinal member via a bored second channel and contacting the second bulbous body causing the second bulbous body to outwardly expand.
US08652171B2	Method and apparatus for soft tissue fixation A surgical method can include passing at least two adjustable loops of a flexible construct through at least the first tissue to extend from an outer surface of the first tissue opposite a tissue engaging surface facing the second tissue, and attaching the two adjustable loops to a first selected area of the second tissue. The method can further include positioning an elongated locking member within the two adjustable loops such that the locking member extends between the two adjustable loops adjacent the outer surface, engaging the locking member with the outer surface by drawing the two adjustable loops towards the outer surface, and compressing the first tissue between the locking member and the second tissue by tensioning the two adjustable loops. Related tissue fixation devices are also provided.
US08652164B1	Rapid use field tourniquet The tourniquet is a lightweight, compact, and highly efficient device that can be used to assist in the control of life threatening extremity hemorrhage. The tourniquet utilizes a ratchet mechanism to obtain a mechanical advantage when tightening the tourniquet. A ratchet assembly is located a distance away from a strap end of the tourniquet and overlays a contiguous portion of the strap, allowing the tourniquet to be tightened while minimizing pinch, and further includes an elongated ratchet lever for ease of use, requiring minimal, if any, fine motor skills. The design also includes an indicator region for assistance in use of the device and a sealed and tapered strap-end with indicator for efficient use.
US08652161B2	Laparoscopic instrument and trocar systems for trans-umbilical laparoscopic surgery Laparoscopic instruments and trocars are provided for performing laparoscopic procedures entirely through the umbilicus. A generally C-shaped trocar provides increased work space between the hands of the surgeon as well as S-shaped laparoscopic instruments placed through the trocar when laparoscopic instrument-trocar units are placed through the umbilicus. In order to facilitate retraction of intra-abdominal structures during a laparoscopic procedure, an angulated needle and thread with either one-or two sharp ends is provided. Alternatively, an inflatable unit having at least one generally C-shaped trocar incorporated within the unit's walls can be placed through the umbilicus following a single incision. Generally S-shaped laparoscopic instruments may be placed through the generally C-shaped trocars to facilitate access to intra-abdominal structures.
US08652158B2	Lancets A return spring arrangement for a lancet (6) is provided by a pair of undulating plastic webs (14) formed integrally with the lancet. The undulations of the two webs (14) are shown out of phase with one another. These webs (14) are flexible and thus are caused to concertina when the tips (15) of the webs hit the interior of a lancet holder on release of a drive spring. The energy stored within the collapsed webs (14) is then released to drive the lancet back within the lancet holder. This positive return of the lancet ensures that a needle (5) will retract safely into the lancet holder, after operation, and does not rely on the spring being locked into the lancet holder and onto the lancet.
US08652155B2	Surgical instruments A surgical device. The surgical device may comprise a transducer configured to provide vibrations along a longitudinal axis and an end effector coupled to the transducer and extending from the transducer along the longitudinal axis. The surgical device also may comprise a lower jaw extending parallel to the end effector. The lower jaw may comprise a clamp face extending toward the longitudinal axis. Also, the lower jaw may be slidable relative to the end effector to bring the clamp face toward a distal end of the end effector.
US08652150B2	Multifunction surgical device A surgical device is disclosed along with methods of using the same. The surgical device may include an outer sheath and a collar assembly. The collar assembly may be coupled to the outer sheath and may include a first arm coupled to the outer sheath at a first hinge; a second arm coupled to the first arm at a second hinge; and a collar coupled to the second arm. The collar assembly may be movable from an un-deployed position where the first arm and the second arm extend the collar distally from the outer sheath to a deployed position where the collar is aligned with the first channel of the outer sheath. Also, the first arm, the second arm, and the collar may be positioned substantially within a cross-sectional area of a distal end of the outer sheath when the collar assembly is in the un-deployed position.
US08652140B2	Device and method for operating a tool relative to bone tissue and detecting neural elements An apparatus for providing medical treatment includes a tool portion configured to operate relative to bone tissue, a handle portion to operate the tool portion, and a nerve monitoring system to detect neural elements. The tool portion includes an insulated shaft comprised of an electrically conductive member and a non-insulated tip. The shaft carries an electrical signal to the non-insulated tip. The handle portion, which is removably and operably connected to the tool portion, incorporates an operating system to rotationally operate the tool portion. Additionally, the nerve monitoring system is linked to the tip and is operable to detect a neural element as a function of a characteristic of the electrical signal on the tip. Upon detection of a neural element, the nerve monitoring system provides a signal to the operating system of the handle portion directing the operating system stop rotation of the tool portion.
US08652138B2	Flexible tissue rasp Methods and devices are described for modifying tissue in a spine of a patient to treat or alleviate spinal stenosis. In one embodiment, a method may include: advancing at least a distal portion of an elongate tissue modification device into an epidural space and between target tissue and non-target tissue in the spine; positioning the tissue modification device so that at least one abrasive surface of the device faces target tissue and at least one non-abrasive surface faces non-target tissue; applying tensioning force at or near separate distal and proximal portions of the tissue modification device; and translating the tissue modification device back and forth while maintaining at least some tensioning force to abrade at least a portion of the target tissue with the at least one abrasive surface. Unwanted damage to the non-target tissue may be prevented via the at least one non-abrasive surface.
US08652136B2	Femoral fracture fixation device A femur fixation device including an elongated nail configured for insertion into the medullary canal of the femur and a buttress element extending from the elongated nail. The buttress element is configured to reinforce the lesser trochanter region of the femur and assist in stabilizing the head portion of the femur.
US08652125B2	Electrosurgical generator user interface An electrosurgical generator is disclosed. The generator includes an output stage configured to generate a waveform, a first input configured to adjust a cut setting representative of a cutting effect of the waveform, and a second input configured to adjust a hemostasis setting representative of a hemostasis effect of the waveform. The generator also includes a controller configured to receive cut and hemostasis settings and to adjust one of a duty cycle, a crest factor and a power level of the waveform to achieve a combined cutting and hemostasis effect based on the cut and hemostasis settings.
US08652117B2	Pharmaceutical composition and nasal rinsing device therefor Vaccine is administered into a nose. A pharmaceutically-acceptable aqueous saline solution carrier comprising from 0.5% to 1.9% salt is provided in a nasal device. The saline solution is administered into a first nasal cavity to rinse the first nasal cavity. The saline solution is added to the first nasal cavity until the saline solution flows via a posterior nasal aperture into a second nasal cavity. A vaccine is then administered into the first nasal cavity.
US08652114B2	Insert with advantageous fastener configurations and end stiffness characteristics for two-piece wearable absorbent article A two-piece wearable absorbent article (such as a diaper) including an outer cover, and particularly, an absorbent insert for use therewith, are disclosed. The insert has a fastener component disposed at either or both a forward region and a rearward region thereof, for fastening the insert within the outer cover. The end of the insert associated with the region bearing the fastener component may have a specified stiffness, to help the insert to retain structural integrity while fastened within an outer cover and while being worn. The insert may include an end support stiffener that helps impart stiffness.
US08652113B2	Disposable absorbent article comprising a printed tag A disposable absorbent article intended to be worn around the waist of a wearer includes a chassis having a front portion, a back portion, and a crotch portion there between, and optionally a waistband. A printed tag is arranged on the inner wearer facing side of the chassis in at least one of the front portion, back portion, and the waistband. The tag has at least one first area which is fixedly attached to the chassis and at least one second area which is unattached. The first fixedly attached area covers an area of at least 5% of the total area of the tag and the second unattached area has a length extending along a side edge of the tag of at least 5 mm and a width of at least 1 mm. The tag as described makes it easier to differentiate between the front and back of the article.
US08652106B2	Locking guidewire straightener A guidewire straightener assembly (50,200,300,400) including a guidewire tube (56,250,450) with a tubular passage therethrough having a first diameter and a distal end including a collar (58,260,462) having a second diameter larger than the first diameter. A guidewire (52,202,402) having a third diameter, smaller than the first diameter is disposed within the tubular passage. When a guidewire straightener (10,210,410) is affixed to the guidewire tube distal end in a first position with its biasing member in the tubular passage, the at least one finger (26,216,416) is biased by the tubular passage into frictional engagement with the guidewire; when disposed in a second position in the collar, the at least one finger is disposed away from frictional engagement with the guidewire.
US08652105B2	Endoluminal access device A surgical access apparatus for providing access inside a body includes a housing having a first port, a tubular member extending distally from the housing and defining a longitudinal axis therealong, wherein the tubular member includes a lumen extending therethrough. a shaft insert disposed in the lumen of the tubular member, wherein the shaft insert forms first, second, and third passageways extending along the lumen of the tubular member, wherein each of the first, second, and third passageways is adapted to receive a surgical instrument; and a first seal assembly covering the first port of the housing and defining a first passage disposed in communication with the first passageway defined by the shaft insert in the tubular member, wherein the first seal assembly is adapted to form a seal around the surgical instrument inserted through the first passage of the first seal assembly.
US08652101B2	Implantation device for metabolite sensors The invention relates to an implantation device for implanting a sensor element for detecting at least one analyte in a bodily fluid or body tissue. The implantation device comprises at least one cannula for piercing a skin surface of a patient. The cannula has at least one holding area for holding the sensor element. The implantation device furthermore has at least one hydraulic container, connected to the cannula, for holding a hydraulic fluid and at least one pressure generation device. The pressure generation device is designed to apply pressure to the hydraulic fluid, wherein the sensor element can be transferred from the cannula into the body tissue using the hydraulic fluid.
US08652099B2	Device for delivering medical treatment A medical device for the delivery of treatment fluid to body vessels is described. The device has a distal (21) and a proximal (20) end with a self-expanding, hollow tubular member (9) and a delivery catheter (10) suitable for deploying a self-expanding, tubular member (9). The tubular member (9) is configured to expand radially to form a central part (11) flanked by two annular ridges, which creates, in situ, an annular lumen that can apply treatment fluid locally to a vessel and a passageway that can maintain the flow of blood through the vessel. The device is particularly suited for minimally invasive and repeatable organ perfusion. A method for organ perfusion is also disclosed.
US08652098B2	Catheter with radiopaque coil A balloon catheter having a radiopaque coil embedded in the catheter's body corresponding to a landmark of the balloon or other location on the catheter body. The radiopaque coil can be viewed under fluoroscopy to located the balloon or other structure of the catheter. The coil can be readily inserted in the manufacturing process by inserting it between two layers that form the catheter body, and then sealing the coil inside the catheter at the desired location. This facilitates both the manufacturing process and prevents the marker from being dislodged during the manufacturing, navigation, or inflation process.
US08652097B2	Systems and methods for combining materials A method of combining a drug in a first container and a liquid in a second container includes placing the first container and the second container in fluid communication with a housing, combining the liquid and the drug in the first container, transferring the liquid and the drug from the first container to the housing, and transferring the liquid and the drug from the housing to a third container.
US08652094B2	Syringe with universal end-piece The present invention relates to a syringe (20) defining a reservoir (21) for containing a liquid and comprising an end-piece (10) encompassing a channel (11) providing a passageway for the transfer of the said liquid, characterized in that the said channel (11) comprises two portions, a first portion (12) and a second portion (13), the said first portion (12) extending from the free distal end (14) of the end-piece (10) in the direction of the reservoir (21), and the said second portion (12) extending between the first portion (12) of the channel (11) and the proximal end (15) of the end-piece (10) and connecting the said first portion (12) to the reservoir, the said first portion (12) having an average diameter that is greater than the average diameter of the said second portion (13).
US08652093B2	System for programming medical pumps with reduced-error Medical pumps may obtain programming data from a database through the use of a remote query process which allows the individual pump to flexibly request data from existing hospital databases, to identify the necessary information in those databases, and to convert that data for use without the need for manual programming or a centralized pump control system.
US08652090B2	Anti-extravasation surgical portal plug The devices and methods shown provide for the minimization of extravasation during arthroscopic surgery. The anti-extravasation surgical portal plug allows a surgeon to drain excess fluids from the soft tissue surrounding the surgical field during arthroscopic surgical procedures.
US08652087B2	Method for use of microdialysis Very accurate measurements of mass transfer can be made rapidly by permitting diffusion of an agent desired to be measured into or out of a small, very precisely known volume of a microdialysis probe, then rapidly pumping or flushing (“pulsing”) the probe with a known volume of fluid as a single pulse. The diffusion and pulsing may be repeated. The method, hereinafter called pulsatile microdialysis (PMD) to distinguish it from prior art continuous flow microdialysis, is useful for measurements in a number of processes, including protein binding, adsorption to binding agents such as activated charcoal, release from microemulsion drug delivery systems, determination of drug diffusion coefficients and concentrations, and for various other purposes.The method is based on mathematical manipulation of Fick's Laws. Resulting equations were verified against experimental data using methazolamide, warfarin and benzocaine as test drugs.
US08652084B2	Arteriovenous shunt with integrated surveillance system A hemodialytic angioacess device for implantation in dialysis patients, comprising an arteriovenous (AV) shunt, anastomotic valves that connect the AV shunt to blood vessels, a valve control system and an integrated surveillance system that measures flow conditions in the blood vessels at the AV shunt, preferably when the valves are closed and the patient is not undergoing dialysis treatment. The flow condition data, which may include data representing the flow rate, pressure, volume and velocity of blood flowing through the vessels, is stored in a memory and transmitted to a health care provider or technician on demand. The data can be used to calculate and monitor important physiological parameters, such as compliance and resistance, for the blood vessels, and help detect and identify dangerous conditions, such as turbulence and stasis, which can contribute to AV shunt failure, vessel injury and other serious complications for the patient.
US08652081B2	Lumbar traction device A lumbar traction device that can alleviate lower back pain is provided. The device includes a harness or girdle that is fitted about the torso region of a patient and an adjustable support assembly in the form of adjustable legs that allow the degree of traction to be adjusted by the patient. The device is safe and easy to use by a patient without constant medical supervision and is particularly suitable for use in domestic or office environments.
US08652078B2	Shower head with water-powered vibrating function A shower head with water-powered vibrating function wherein a diverting member is disposed in the water diversion chamber which is operable by a diverting member actuating means between a normal shower position and a massage shower position. At the normal shower position the diverting member diverts water flow received from the water diversion chamber inlet to leave the water diversion chamber through the first water diversion chamber outlet for exiting the shower head through a first water outlet; and at the massage shower position, the diverting member diverts water flow received from the water diversion chamber inlet to leave the water diversion chamber through the second water diversion chamber outlet for entering the turbine chamber for rotating the turbine and thereafter leaving the turbine chamber to exit the shower head through a second water outlet.
US08652076B2	Active hand-extension/flexion device A hand movement device comprises a glove for positioning about a hand of a user, a first anchor element adapted to be positioned about a base surface of glove, a second anchor element adapted to be positioned at a tip of a finger portion of the glove, an active spring member positioned between the first and second anchor elements, said active spring member being fixedly secured to said first anchor element and moveable through said second anchor element to thereby allow said spring member to bend about a joint of the finger when said finger is flexed, an activating element positioned adjacent the active spring member to heat or cool said active spring member thereby causing the spring member to bend or straighten, and an intermediary support device for housing said spring element and for connecting the first anchor element to said second anchor element.
US08652071B2	Systems, devices, and methods for interpreting movement According to some exemplary embodiments, a method or system can involve associating a plurality of biokinetographic comparison results with a first specific dysfunction from a group of specific dysfunctions, each of the biokinetographic comparison results obtained from a comparison of a biokinetographic value to a standard for a corresponding biokinetographic variable.
US08652066B2	Involuntary contraction induced pressure as a medical diagnostic tool Techniques for detecting stress urinary incontinence use a pressure sensing catheter the electrical indications of which are applied to a processing unit for detecting pressure levels generated during involuntary coughs. The involuntary coughs are induced preferentially by using a nebulized composition of L-tartrate in a pharmaceutically acceptable carrier. The area under the curve generated from pressure samples is calculated and used in conjunction with the detection of urine leakage to determine the existence of stress urinary incontinence.
US08652060B2	Perfusion trend indicator A perfusion trend indicator inputs a plethysmograph waveform having pulses corresponding to pulsatile blood flow within a tissue site. Perfusion values are derived corresponding to the pulses. Time windows are defined corresponding to the perfusion values. Representative perfusion values are defined corresponding to the time windows. A perfusion trend is calculated according to differences between representative perfusion values of adjacent ones of the time windows.
US08652057B2	Recyclable or biodegradable blood pressure cuff A blood pressure cuff is defined by a first sheet, having an opening, and a second sheet. The second sheet is attached to a bottom of the first sheet to form an interior inflatable portion between the first sheet and the second sheet, with the opening of the first sheet fluidly interconnecting the interior inflatable portion with an exterior of the cuff. The blood pressure cuff is made from a single type of material and can be recycled, biodegradable, or composted.
US08652054B2	Biologic information detecting apparatus In measurement requiring application of pressure to a tissue of a living body such as blood pressure measurement, noise due to vibration tends to occur. It is difficult to accurately measure a pulse wave and a blood pressure value. It is also difficult to measure blood pressure in life activities or to measure blood pressure at intervals or continuously where a tonometer is always attached. There is consequently a problem of holding a biologic information detecting apparatus. The present invention solves the problems by providing an easy-to-wear biologic information detecting apparatus for stably detecting biologic information. The biologic information detecting apparatus includes a sensor for detecting biologic information in a pair of arms connected via a spindle, and the sensor is tightly attached to a projecting part in a living body, particularly, a tragus of an auricle.
US08652053B2	Biologic information detecting apparatus In measurement requiring application of pressure to a tissue of a living body such as blood pressure measurement, noise due to vibration tends to occur. It is difficult to accurately measure a pulse wave and a blood pressure value. It is also difficult to measure blood pressure in life activities or to measure blood pressure at intervals or continuously where a tonometer is always attached. There is consequently a problem of holding a biologic information detecting apparatus. The present invention solves the problems by providing an easy-to-wear biologic information detecting apparatus for stably detecting biologic information. The biologic information detecting apparatus includes a sensor for detecting biologic information in a pair of arms connected via a spindle, and the sensor is tightly attached to a projecting part in a living body, particularly, a tragus of an auricle.
US08652051B2	Contact pressure sensing apparatus for use with exercise equipment sensors Contact pressure sensing apparatus for use with exercise equipment sensors are described. An example apparatus includes a sensor to detect a physiological condition of a user of an exercise device through physical contact with the user and a pressure sensor to detect a contact pressure applied by the user to the sensor.
US08652050B2	Miniature actuator mechanism for intravascular imaging The present invention relates to a new intravascular imaging device based on a Shape Memory Alloy (SMA) actuator mechanism embedded inside an elongate member such as a guide wire or catheter. The present invention utilizes a novel SMA mechanism to provide side-looking imaging by providing movement for an ultrasound transducer element. This novel SMA actuator mechanism can be easily fabricated in micro-scale, providing an advantage over existing imaging devices because it offers the ability to miniaturize the overall size of the device, while the use of multiple transducer crystals maximizes field of view. Also disclosed are methods of using the same.
US08652048B2	Implant and system for predicting decompensation An implant predicts decompensation of a patient's heart based on an acoustic pressure measurement. The implant includes first and second acoustic transducers, which are matched to each other and which rest in/on the patient's thorax. The first acoustic transducer emits an acoustic signal which has at least one first signal portion having a first frequency. The second acoustic transducer is designed to receive and re-emit the emitted acoustic signal, or to reflect it, such that the first acoustic transducer receives the emitted acoustic signal. A signal processing unit communicates with at least one of the two acoustic transducers and determines an attenuation value as a function of the attenuation of the received acoustic signal versus the originally emitted acoustic signal, and provides a prediction signal as a function of a comparison of the attenuation value to a threshold value, wherein the prediction signal indicates the development of decompensation.
US08652047B2	Apparatus and method for automatically measuring the volume of urine in a bladder using ultrasound signals The method of accurately measuring the volume of urine in a bladder includes generating a plurality of ultrasound scan planes using the received ultrasound signals; detecting distances between the front and back walls of the bladder for each scan line in the ultrasound scan planes; determining an area of the bladder using the detected distances of the scan lines for each ultrasound scan plane; generating a virtual radius of the bladder using the determined area of the bladder for each ultrasound scan plane; determining a calibration coefficient for each ultrasound scan plane using the detected distances of the scan lines; calibrating the virtual radius of the bladder for each ultrasound scan plane using the calibration coefficient; determining the volume of urine in the bladder by calculating the volume of a sphere of which the radius is the average of the calibrated virtual radii for the ultrasound scan planes.
US08652043B2	Analyte monitoring device and methods of use An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor.
US08652031B2	Remote guidance system for medical devices for use in environments having electromagnetic interference A remote guidance system for a medical device is provided that is capable of use with magnetic resonance imaging and other environments with a relatively high level of electromagnetic interference. In one embodiment, a fluid control system controls delivery of fluid to a fluid conduit supplying a fluid chamber of a fluid housing. A piston disposed within the fluid chamber moves in response to a change in fluid displacement in the chamber and causes corresponding movement of the medical device within a body. In another embodiment, means are provided for controlling a connector coupled to the medical device at a location outside the body wherein movement of the connector causes a corresponding movement of the medical device. A sensor generates a signal indicative of a characteristic associated with movement of the medical device. The sensor includes an optic fiber that transmits a light wave indicative of the characteristic.
US08652030B2	Two-part bending endoscope A two-part bending endoscope includes: a first bending part which configures one side of a bending portion; a second bending part which configures the other end side of the bending portion; and a bending portion operation apparatus including a first operation device for causing the first bending part to perform a bending action and a second operation device for causing the second bending part to perform a bending action, wherein the bending portion operation apparatus includes a selective power-transmitting mechanism section which enables at least a bending action of the first bending part by the first operation device, and an interlocking operation of the second bending part and the first bending part by the second operation device.
US08652028B2	Endoscopic instrument system having reduced backlash control wire action An endoscopic instrument has a control member, a portion of the member having an outer surface with a non-circular cross-sectional shape. The non-circular cross-sectional shape may be provided to the control member by providing peripheral projections or fins along the length of the portion or by providing the periphery of the portion with a polygonal shape. Where fins are used, the fins are preferably quite small and only have a minimal effect on the fluid flow cross-sectional area between the interior of the endoscope instrument shaft and the central control member. The resulting instrument has significantly reduced backlash in end effector assembly manipulation, while maintaining adequate fluid flow in the endoscope shaft. According to a second embodiment of the invention, a portion of the interior of the shaft of the endoscopic instrument has an interior surface having a non-circular cross-sectional shape by the inclusion of a plurality of radially spaced and inwardly directed ribs or by being polygonally shaped. The resulting endoscopic instrument likewise reduces the backlash experienced in operating the distal end effector assembly.
US08652027B2	Adjustable applicator for urinary incontinence devices An applicator for urinary incontinence devices has an insertion barrel, a deployment plunger, and an adjustable insertion depth indicator. The applicators are useful to correct for a consumer's body mass index to ensure that urinary incontinence devices are placed in the appropriate position to be effective.
US08652026B2	Disposable urine incontinence device A disposable urinary incontinence device comprises a liquid-stable resilient member, and a cover sheet that envelops the liquid-stable resilient member to form an elongated member having a tubular profile. The elongated member has a first end, a second end, a first fold region disposed between the first end and the second end, a second fold region disposed between the first end and the first fold region, a third fold region disposed between the second end and the first fold region, a first portion located between the first end and the second fold region, a second portion located between the second end and the third fold region, a third portion located between the first fold region and a second fold region, and a fourth portion located between the first fold region and the third fold region to form a W-shaped incontinence device.
US08652015B2	Safety device A safety device (20) for a gymnastic machine (1) provided with a frame (5) and with a gravitational load group (10) connected to an interface (2) designed to allow a user of the gymnastic machine (1) to perform exercises against the action of the load group (10); the load group (10) comprising a movable equipment (19) provided with at least one load element (11) carried, in a freely sliding manner along a given direction (V), by respective guiding elements (12) associated to the frame (5); the safety device (1) comprising a return group (21) suitable, in use, to exert a given return force (F) on the movable equipment (19) so as to prevent substantially inertial ascending displacements thereof.
US08652014B2	Heavy training bag The present invention is a heavy training bag for pugilistic, martial and other similar arts, which provides uniform resistance and contains non-settling filler material. The bag comprises an optional support core contained within a cushion core, which in turn is contained within an impact core, which in turn is contained within an optional outer cover; further wherein the impact core is comprised of at least a rib, but preferably, a plurality of ribs.
US08652012B2	Color changing gyroscopic exerciser A gyroscopic wrist exerciser has a transparent plastic housing and a gyroscopic rotor mounted on an axle rotating on a primary axis of rotation about the axle. Ends of the axle are extended into a circumferential housing groove disposed on an inside surface of the transparent plastic housing to rotate in a secondary axis of rotation about the circumferential groove to provide precession of the gyroscopic rotor. A permanent magnet cooperating with a coil produces an electric current proportional to the speed of the rotor. A microcontroller connected to and powered by the coil has three separate outputs, namely a first output, a second output and a third output which receive degrees of voltage depending upon an input voltage from the coil. A first LED chip, a second LED chip, and a third LED chip are connected to the microcontroller at the three outputs.
US08652004B2	Method for operating a vehicle drive train having a driving machine and having a transmission apparatus having a plurality of shift elements A method of operating a vehicle drive train having a drive machine, a transmission apparatus having a plurality of shift elements and an output drive. The plurality of shift elements are engaged or disengaged in a power flow for achieving different transmission ratios within the transmission apparatus. The output drive is coupled to a transmission output shaft and the drive machine is coupled to a transmission input shaft of the transmission apparatus. Upon a request to interrupt power flow within the transmission apparatus, between the transmission input shaft and the transmission output shaft, a maximum number of shift elements are transferred to and/or held in an engaged operating state, and the remaining portion of the shift elements are transferred to and/or held in a disengaged operating state with the transmission output shaft being rotatable.
US08652000B2	Clutch type driving mechanism for hybrid powered vehicle A clutch type driving mechanism used in a hybrid powered vehicle is disclosed to include a motor, a speed reducing mechanism, a hollow shaft, an output shaft and first and second one-way clutches. The motor provides a rotational kinetic energy through the hollow axle to the speed reducing mechanism. The speed reducing mechanism and the output shaft transfer a unidirectional rotary motion to the hollow shaft through the first one-way clutch and the second one-way clutch respectively. Thus, when the output shaft works as a drive shaft, it does not transfer the rotary motion to the speed reducing mechanism, avoiding power loss and allowing transfer of the rotational kinetic energy rapidly and efficiently without bearing much load.
US08651998B2	Method for controlling a hybrid drive A method is for controlling a hybrid drive of a vehicle, which includes at least one internal combustion engine and at least one electric machine, having a first clutch situated between the electric machine and the drive train of the vehicle and a second clutch situated between the electric machine and the internal combustion engine. In the method, a predefinable clutch torque is applied to the second clutch for a start of the internal combustion engine by the operating electric machine, the rotational speed of the internal combustion engine is monitored, and the clutch torque is incremented to a higher value if the rotational speed of the internal combustion engine is less than a predefinable threshold value within a predefinable time interval.
US08651991B1	Drive module with parking brake A drive module that includes a housing, first and second axle shafts, a differential assembly, a propulsion motor, a brake element fixed to the housing, a torque-vectoring transmission and a mode gear. The differential assembly is mounted in the housing for rotation about a rotational axis and has a differential case and a pair of output members. A first one of the output members is coupled to the first axle shaft for common rotation. The torque-vectoring transmission cooperates with the differential assembly to transmit rotary power to the second axle shaft. The mode gear is movable between a first position and a second position. Positioning of the mode gear in the first position permits transmission of rotary power between the propulsion motor and the differential assembly. Positioning of the mode gear in the second position couples the differential assembly to the housing to inhibit rotation of the first axle shaft.
US08651990B2	Transmission hydraulic control system having an accumulator A hydraulic control system for actuating at least one torque transmitting device in a transmission includes a sump, a pump in communication with the sump, and an accumulator. A first control device and a second control device control the communication of hydraulic fluid between the pump, the accumulator, and the torque transmitting device.
US08651989B2	Multi-mode drive unit Multi-mode operation is provided for an electrically variable transmission for a motor vehicle. The multi-mode electrically variable transmission provides for multiple gear ratios and power flow configurations including fixed gear operation. An improved input-split planetary gear set configuration is provided for the multi-mode electrically variable transmission. The multi-mode electrically variable transmission may be operated in its desired efficiency and/or performance range more frequently. Further, the transmission reduces clutch torques and provides improved functionality in range-extended electric vehicles and battery electric vehicles. The multi-mode electrically variable transmission is provided with a fixed gear operating capability for improved highway cruising and incorporates a reverse gear for reverse operation.
US08651986B2	Drive clutch for a continuously variable transmission with engine braking and built in belt protection A drive clutch for a continuously variable transmission that includes an input shaft designed to engage with an engine. A sheave assembly is mounted about the input shaft. A bearing assembly separates the sheave assembly from the input shaft such that the input shaft can rotate independently from the sheave assembly. At least one sheave clutch assembly is positioned about the input shaft. The sheave clutch assembly is configured to provide engagement between the sheave assembly and the input shaft when the rotation of the input shaft increases above a certain threshold value. An axial control mechanism is mounted on the input shaft adjacent to the second sheave. The axial control mechanism controls the movement of the second sheave toward and away from the first sheave as a function of the speed of the input shaft. A continuously variable transmission including the drive clutch and a driven clutch is also disclosed.
US08651981B2	Protective screen A pitching screen which provides a support structure having an arcuate support element which defines the boundary of the pitching screen and about which a ball can be pitched toward a pitching target.
US08651980B2	Combination training device for ball sports A training device for ball sports includes a frame member which supports both an elastic surface for rebounding a ball, along with an inelastic surface which absorbs the kinetic energy of the ball and allows it to drop to the ground, which is designed as a combination apparatus that includes both a ball rebounding surface and a ball stopping surface, in order to provide a variety of training activities and which may be transported easily by a coach or an individual using it for practice.
US08651976B1	Multiple layer golf ball A golf ball comprising a core comprising an inner core center and an outer core layer disposed over the inner core center. The inner core center has a deflection of greater than 0.210 inch under a load of 100 kilograms, and the entire the core has a deflection ranging from 0.130 inch to 0.105 inch under a load of 100 kilograms. A mantle layer is disposed over the core and a cover is disposed over the mantle.
US08651968B1	Rotatable amusement apparatus An amusement apparatus includes an elongate member having an upper extremity and a lower extremity with a pivot point. A self-contained child-supporting assembly is mounted to the elongate member between the upper and lower extremities for rotation and includes a seat to receive a child in a sitting position, handles to be taken up by hand by a child seated on the seat, and footrests to provide foot support for a child seated on the seat. A leveraging arm extends from the upper extremity of the elongate member to an outer end having an upright handle. The leveraging arm has a transverse handle between the upper extremity of the elongate member and the upright handle. The transverse and upright handles are available to be taken up by hand to reciprocally pivot the elongate member at the pivot point to impart rotation to the child-supporting assembly about the elongate member.
US08651965B2	Vibration damping device A vibration damping device capable of reducing a change in an order frequency of a reciprocating motion of a pendulum resulting from eccentricity of rotational members therein. The vibration damping device comprises a pendulum damping mechanism having a mass to dampen the torsional vibrations by an oscillating motion thereof resulting from the torsional vibrations. An inertial body is arranged in the prime mover side of the rotary shaft, an elastic damping mechanism is connected with a transmission side of the inertial body in a power transmittable manner, a pendulum damping mechanism is connected with the transmission side of the elastic damping mechanism in a power transmittable manner, and a torque limiter mechanism is connected with the transmission side of the pendulum damping mechanism in a power transmittable manner.
US08651962B2	Amusement system having communication function A game machine (2) receives via a server apparatus (3) and displays on a game image (110), a comment transmitted from a terminal apparatus (7) of a user. When a user of the game machine (2) indicates a reply to the comment, the game machine (2) requests the server apparatus (2) to transmit as a reply comment, a comment for reply which is specified in advance by the user, to a user who is a transmitter of the comment to be replied. By following the request, the server apparatus (3) transmits the comment for reply to the terminal apparatus (7) of the user who is a destination of reply.
US08651961B2	Collaborative electronic game play employing player classification and aggregation A method and system tracks, analyzes or sorts behaviors of user or players across a network to draw correlations from, or characterizations of, those user or players and identifies similarly characterized or mutually complementary user or players. For example, the method automatically obtains player data regarding interactions by each of multiple players with a multiplayer electronic game via each player's corresponding data processing device connected via the network. The method can then sort, classify or suggest additional activities, games, groups, or other different activities or actions for the players.
US08651958B2	System for tournament on-line game by batch processing A method for a tournament-type on-line game by batch processing includes generating an independent game turn determining both participants in each match of the game, to every participant; providing match information, which includes the game turn information, victory criterion information determined in association with the game turn information and allowing the participant to win in each match until stage K, and an input circumstance for inputting variable information, to a client of the participant; receiving variable information from the client through the provided match information; and operating all of the received variable information by batch processing to determine winners until stage K, wherein an operation result of the variable information received from both clients of each match is compared with the victory criterion information so that the participant having the victory criterion information identical to the operation result is determined as a winner of each match.
US08651953B2	Electronic game device and method of using the same An electronic question and answer game device in accordance with the present invention comprises a housing that has several side walls or surfaces. A display screen is disposed on one of the sides. The display screen is configured to present a question to the user of the electronic device. The electronic game device includes several mechanisms that vary the methods in which a user can play the game.

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