最新美国发明专利第2013-10-01期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US08546668B1	Maize variety hybrid X95B333 A novel maize variety designated X95B333 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X95B333 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X95B333 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X95B333, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X95B333. This invention further relates to methods for producing maize varieties derived from maize variety X95B333.
US08546667B1	Maize variety hybrid X05B902 A novel maize variety designated X05B902 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X05B902 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X05B902 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X05B902, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X05B902. This invention further relates to methods for producing maize varieties derived from maize variety X05B902.
US08546665B1	Maize variety hybrid X90B059 A novel maize variety designated X90B059 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X90B059 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X90B059 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X90B059, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X90B059. This invention further relates to methods for producing maize varieties derived from maize variety X90B059.
US08546662B2	Tomato hybrid PX 02461111 The invention provides seed and plants of tomato hybrid PX 02461111 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of tomato hybrid PX 02461111 and the parent lines thereof, and to methods for producing a tomato plant produced by crossing such plants with themselves or with another tomato plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
US08546661B2	Soybean variety XB30AL11 A novel soybean variety, designated XB30AL11 is provided. Also provided are the seeds of soybean variety XB30AL11, cells from soybean variety XB30AL11, plants of soybean XB30AL11, and plant parts of soybean variety XB30AL11. Methods provided include producing a soybean plant by crossing soybean variety XB30AL11 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB30AL11, methods for producing other soybean varieties or plant parts derived from soybean variety XB30AL11, and methods of characterizing soybean variety XB30AL11. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB30AL11 are further provided.
US08546658B1	Soybean variety XB38AL11 A novel soybean variety, designated XB38AL11 is provided. Also provided are the seeds of soybean variety XB38AL11, cells from soybean variety XB38AL11, plants of soybean XB38AL11, and plant parts of soybean variety XB38AL11. Methods provided include producing a soybean plant by crossing soybean variety XB38AL11 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB38AL11, methods for producing other soybean varieties or plant parts derived from soybean variety XB38AL11, and methods of characterizing soybean variety XB38AL11. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB38AL11 are further provided.
US08546656B1	Soybean variety XBP29005 A novel soybean variety, designated XBP29005 is provided. Also provided are the seeds of soybean variety XBP29005, cells from soybean variety XBP29005, plants of soybean XBP29005, and plant parts of soybean variety XBP29005. Methods provided include producing a soybean plant by crossing soybean variety XBP29005 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XBP29005, methods for producing other soybean varieties or plant parts derived from soybean variety XBP29005, and methods of characterizing soybean variety XBP29005. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP29005 are further provided.
US08546654B2	Soybean cultivar S090090 A soybean cultivar designated S090090 is disclosed. The invention relates to the seeds of soybean cultivar S090090, to the plants of soybean S090090, to plant parts of soybean cultivar S090090, and to methods for producing a soybean plant produced by crossing soybean cultivar S090090 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety S090090, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S090090, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar S090090 with another soybean cultivar.
US08546650B2	Cucumber hybrid PS 14763462 and parents thereof The invention provides seed and plants of cucumber hybrid PS 14763462 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of cucumber hybrid PS 14763462 and the parent lines thereof, and to methods for producing a cucumber plant produced by crossing such plants with themselves or with another cucumber plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
US08546647B2	Pathogen inducible plant thehalose-6-phophate phophatase gene promoters and regulatory elements The invention provides plant gene promoters and regulatory elements that are root-specific and/or induced by parasitic nematodes. The promoters of the invention are useful for controlling expression of nucleic acids of interest in plants' roots. The invention also provides expression cassettes including the plant gene promoters and regulatory elements of the invention, transgenic plants containing such expression cassettes, and methods of producing such transgenic plants.
US08546646B2	Grain quality through altered expression of seed proteins The present invention is directed to compositions and methods for altering the levels of seed proteins in cereal grain. The invention is directed to the alteration of seed protein levels in plant grain, resulting in grain with increased digestibility/nutrient availability, improved amino acid composition/nutritional value, increased response to feed processing, improved silage quality, and increased efficiency of wet milling.
US08546645B2	Production of modified fatty acids in plants through rDNA targeted integration of heterologous genes The present invention relates to transgenic plants comprising a plurality of nucleic acids heterologous to said plant, each of said nucleic acid comprising a coding sequence operably linked to one or more regulatory elements for directing expression of said coding sequence in said plant, said nucleic acid being stably integrated at or adjacent to rDNA sequences, or a seed, organ, tissue, part or cell thereof, or a descendant of said plant, seed, organ, tissue, part or cell; methods of producing the transgenic plants; and methods of producing oil using the transgenic plants.
US08546643B2	Pig model for atherosclerosis The present invention relates to a genetically modified pig as a model for studying atherosclerosis. The modified pig model displays one or more phenotypes associated with atherosclerosis. Disclosed is also a modified pig comprising a mutation in the endogenous ApoE gene or part thereof, LDL gene or part thereof, LDL receptor gene, or transcriptional or translational product or part thereof. The invention further relates to methods for producing the modified pig; and methods for evaluating the effect of a therapeutical treatment of atherosclerosis; methods for screening the efficacy of a pharmaceutical composition; and a method for treatment of a human being suffering from atherosclerosis are disclosed.
US08546642B2	Absorbent article with slitted absorbent core An absorbent article, such as a sanitary napkin, includes a top sheet and a back sheet with a resilient, composite absorbent core sandwiched therebetween. To decrease the stiffness, the absorbent core includes an outer line and an inner line on each side of a longitudinal centerline. The outer line includes a plurality of slits having spaces therebetween, and the outer line extends convexly when viewed from the longitudinal centerline. The plurality of slits in the absorbent core impart better bending ability of the absorbent article, particular for stiff airlaid absorbent cores.
US08546639B2	Urine suction device A urine suction device improved to achieve quick urine which includes a urine receiver unit and a urine detector unit. The urine detector unit includes a pair of electrode assemblies adapted to output a detection signal as soon as it is wetted with urine. The pair of electrode assemblies is sandwiched between a liquid-pervious first sheet and a liquid-pervious second sheet. The first and second sheets are put flat and joined together along joint zones provided outside respective pairs of opposite side edges of the electrode assemblies. Along the respective joint zones, at least one of the first and second sheets has its thickness locally reduced and the first and second sheets are kept in close contact with each other along the joint zones and in the vicinity of the joint zones.
US08546635B1	Methods and apparatuses for preparing upgraded pyrolysis oil Methods and apparatuses for preparing upgraded pyrolysis oil are provided herein. In an embodiment, a method of preparing upgraded pyrolysis oil includes providing a biomass-derived pyrolysis oil stream having an original oxygen content. The biomass-derived pyrolysis oil stream is hydrodeoxygenated under catalysis in the presence of hydrogen to form a hydrodeoxygenated pyrolysis oil stream comprising a cyclic paraffin component. At least a portion of the hydrodeoxygenated pyrolysis oil stream is dehydrogenated under catalysis to form the upgraded pyrolysis oil.
US08546632B2	Methods for removing unsaturated aliphatic hydrocarbons from a hydrocarbon stream using an acidic molecular sieve Disclosed is a method for removing unsaturated aliphatic compounds from a hydrocarbon feed stream by contacting the hydrocarbon feed stream with an acidic molecular sieve to produce a hydrocarbon effluent stream having a lower unsaturated aliphatic content relative to the hydrocarbon feed stream. The hydrocarbon feed stream comprises an aromatic compound, a nitrogen compound, and an unsaturated aliphatic compound.
US08546629B2	Methods for co-production of alkylbenzene and biofuel from natural oils Embodiments of methods for co-production of linear alkylbenzene and biofuel from a natural oil are provided. A method comprises the step of deoxygenating the natural oils to form a stream comprising paraffins. A first portion of the paraffins are dehydrogenated to provide mono-olefins. Then, benzene is alkylated with the mono-olefins under alkylation conditions to provide an alkylation effluent comprising alkylbenzenes and benzene. Thereafter, the alkylbenzenes are isolated to provide the alkylbenzene product. A second portion of the paraffins is processed to form biofuel.
US08546627B2	Renewable compositions The present invention is directed to renewable compositions derived from fermentation of biomass, and integrated methods of preparing such compositions.
US08546626B2	Method of converting effluents of renewable origin into fuel of excellent quality by using a molybdenum-based catalyst The invention is concerned with a supported or unsupported catalyst comprising an active phase constituted by a sulfur-containing group VIB element, the group VIB element being molybdenum, and a hydrodeoxygenation process with a yield of hydrodeoxygenation product which is greater than or equal to 90% of charges from renewable sources using a catalyst according to the invention.
US08546625B2	Conversion of natural products including cellulose to hydrocarbons, hydrogen and/or other related compounds A process for the conversion of sugars and/or other biomass to produce hydrocarbons, hydrogen, and/or other related compounds is described. In one aspect, the process includes fermenting biomass to produce one or more organic intermediates, for example, a carboxylic acid, and optionally, hydrogen. The carboxylic acids may then be decarboxylated to produce carbon dioxide and one or more hydrocarbon compounds. Also described are steps to further react the hydrocarbon compounds to form polymers, hydrocarbon compounds having at least 4 carbon atoms, or the like.
US08546624B2	Azeotrope-like composition of 2-chloro-3,3,3-trifluoropropene (HCFC-1233xf) and hydrogen fluoride (HF) Provided are azeotropic and azeotrope-like compositions of 2-chloro-3,3,3-trifluoropropene (HCFO-1233xf) and hydrogen fluoride (HF). Such azeotropic and azeotrope-like compositions are useful as intermediates in the production of 2,3,3,3-tetrafluoropropene (HFO-1234yf).
US08546623B2	Dehydrogenationhalogenation process for the production of C3 -C6-(hydro)fluoroalkenes The invention relates to a process for preparing a C3-6 hydrofluoroalkene comprising dehydrohalogenating a C3-6 hydrohalofluoroalkane in the presence of a zinc/chromia catalyst.
US08546621B2	Process for the manufacture of 3,7-dimethyl-1-octen-3-ol The present invention is directed to a process for the manufacture of 3,7-dimethyl-1-octen-3-ol comprising the following steps: a) hydrogenation of 6-methyl-5-hepten-2-on to 6-methyl-2-heptanon in the presence of hydrogen and a palladium containing catalyst on a carrier selected from the group consisting of carbon, calcium carbonate and aluminum oxide. b) reaction of 6-methyl-2-heptanon with acetylene to 3,7-dimethyl-1-octin-3-ol in the presence of ammonia and potassium hydroxide and in the absence of any additional organic solvent; c) hydrogenation of 3,7-dimethyl-1-octin-3-ol to 3,7-dimethyl-1-octen-3-ol in the presence of hydrogen and a palladium containing catalyst on a carrier selected from the group consisting of calcium carbonate, aluminum oxide, silica, porous glass, carbon or graphite, and barium sulphate, with the proviso that the catalyst additionally contains lead when the carrier is calcium carbonate. The present invention is further directed to a process for the manufacture of isophytol and vitamin E, where a thus produced 3,7-dimethyl-1-octen-3-ol is used as starting material.
US08546620B2	Ethylene glycol removal of residual glycol impurities A process includes receiving a process stream including at least about 80.0% by weight propylene glycol, and contacting the process stream with an absorbent material to produce a product stream. The absorbent material is configured to preferentially absorb ethylene glycol relative to propylene glycol.
US08546618B2	Method for preparing 3-trifluoromethyl chalcones Disclosed is a method for preparing a compound of Formula 1 wherein Q and Z are as defined in the disclosure comprising distilling water from a mixture comprising a compound of Formula 2, a compound of Formula 3, a base comprising at least one compound selected from the group consisting of alkaline earth metal hydroxides of Formula 4 wherein M is Ca, Sr or Ba, alkali metal carbonates of Formula 4a wherein M1 is Li, Na or K, 1,5-diazabicyclo[4.3.0]non-5-ene and 1,8-diazabicyclo[5.4.0]undec-7-ene, and an aprotic solvent capable of forming a low-boiling azeotrope with water. Also disclosed is a method for preparing a compound of Formula 2 comprising (1) forming a reaction mixture comprising a Grignard reagent derived from contacting a compound of Formula 5 wherein X is Cl, Br or I with magnesium metal or an alkylmagnesium halide in the presence of an ethereal solvent, and then (2) contacting the reaction mixture with a compound of Formula 6 wherein Y is OR11 or NR12R13, and R11, R12 and R13 are as defined in the disclosure. Further disclosed is a method for preparing a compound of Formula 7 wherein Q and Z are as defined in the disclosure, using a compound of Formula 1 characterized by preparing the compound of Formula 1 by the method disclosed above or using a compound of Formula 1 prepared by the method disclosed above.
US08546616B2	Polyetheramine macromonomers comprising two neighboring hydroxyl groups and their use for producing polyurethanes The object of the invention are compounds of the formula (2) wherein R1 is H, methyl or ethyl, R2 is C1- to C4 alkyl, A is a C2- to C4 alkylene group, m is number from 10 to 400, n is 1, 2, 3, 4, or 5, a method for their production and their use in the production of polyurethane prepolymers.
US08546615B2	Solid dapoxetine The present invention relates to solid racemic dapoxetine, solid dapoxetine S(+)enantiomer, processes for their preparation and their use in the pharmaceutically active compound dapoxetine acid addition salt, and pharmaceutical compositions thereof.
US08546613B2	SGK1 inhibitors for the prophylaxis and/or therapy of viral diseases and/or carcinomas The present invention relates to a compound of formulas I, Ia, Ib and II, wherein R1 to R11 are herein defined.
US08546610B2	Method for preparing phenylalanine derivatives having quinazoline-dione skeleton and intermediates for use in the preparation of the derivatives A method for preparing a phenylalanine derivative having a quinazoline-dione ring represented by the following formula (1) or a pharmaceutically acceptable salt thereof, comprising the following steps (a), (b) and (c): (a) reacting an acyl phenylalanine derivative represented by the following formula (2): with a carbonyl group-introducing reagent and a specific anthranilic acid derivative to thus form the corresponding carboxy-asymmetric urea derivative; (b) converting the carboxy-asymmetric urea derivative into the corresponding quinazoline-dione derivative in the presence of a carboxyl group-activating agent: (c) if desired, substituting an N-alkyl group for the hydrogen atom bonded to the nitrogen atom present in the quinazoline-dione ring of the quinazoline-dione derivative using an N-alkylation agent and then deprotecting the resulting product, when the substituent R3′ which is a group corresponding to R3 is protected. According to this method, there can be obtained a phenylalanine derivative having a quinazoline-dione skeleton in a industrially favorably high yield.
US08546608B2	Proteasome inhibitors and methods of using the same The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.
US08546607B2	Cross-coupling of phenolic derivatives Embodiments of the invention provide methods and materials for chemical cross-coupling reactions that utilize unconventional phenol derivatives as cross-coupling partners. Embodiments of the invention can be used to synthesize a variety of useful organic compounds, for example the anti-inflammatory drug flurbiprofen.
US08546605B2	Process for the preparation of isocyanates The invention provides a multistage process for continuously preparing organic, distillable polyisocyanates, preferably diisocyanates, more preferably aliphatic or cycloaliphatic diisocyanates, by reacting the corresponding organic polyamines with carbonic acid derivatives and alcohols to low molecular mass monomeric polyurethanes, and thermally cleaving said polyurethanes, in which at defined reaction stages the polyisocyanates prepared and unusable residues are separated off, and reusable by products and intermediates are recycled to upstream stages.
US08546603B2	Substituted cyclopentanes having prostaglandin activity Disclosed herein are compounds having a formula: Therapeutic methods, medicaments, and compositions related thereto are also disclosed.
US08546600B2	Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite The present invention provides a step-wise process for preparation of a bisphosphite. In step (a) the process prepares a phosphoromonochloridite in high yield, by contacting phosphorus trichloride with an aromatic diol in a slurry under reaction conditions and in the presence of a second aromatic diol to produce a mixture comprising the phosphoromonochloridite, the second aromatic diol, and excess PCl3. The slurry comprises less than 5 mole percent of a nitrogen base, and the organic solvent is selected for its low hydrogen chloride solubility. After removing the excess PCl3, a nitrogen base is added to effect condensation of the phosphoromonochloridite with the second aromatic diol to yield the bisphosphite. The invention particularly provides a process for preparing 6,6′-(3,3′,5,5′-tetra-tert-butylbiphenyl-2,2′-diyl)bis(oxy)didibenzo[d,f][1,3,2]dioxaphosphepine by the above route.
US08546598B2	Silane compounds having a cyclic carbon chain including an alkyne function for functionalizing solid substrates and immobilizing biological molecules on said substrates The invention relates to a silane compound including a cycloalkyne functionality, to a method for functionalising a solid substrate, and to the solid substrate thus produced. The silane compound of the invention corresponds to the formula X-E-A-Z where X is a silyl group, E is an organic spacer group, A is a single bond or a —CONH—, —NHCO—, —OCH2CONH—, —NHCOCH2O—, —O— or —S— group, and Z is a cycloalkyne or heterocycloalkyne with at least 8 members. The invention is particularly suitable for use in the field of medicine.
US08546597B2	Organic silane compound for forming Si-containing film by plasma CVD and method for forming Si-containing film An organic silane compound for forming a Si-containing film by plasma CVD is provided. The silane compound contains 2 or more silicon atoms bonded by an intervening straight chain or branched oxygen-containing hydrocarbon chain having 4 to 8 carbon atoms containing a bond represented by Cp—O—Cq wherein p and q independently represent number of carbon atoms with the proviso that 2≦p≦6 and 2≦q≦6 and the carbon chains do not contain an unsaturated bond which conjugates with the oxygen atom, wherein all of the 2 or more silicon atoms has 1 or more hydrogen atom or an alkoxy group having 1 to 4 carbon atoms.
US08546596B2	Hydrosilylation method Compounds containing carbon-carbon double bonds and/or carbon-carbon triple bonds are hydrosilylated with linear organopolysiloxanes having diorganosiloxy units and Si—H groups, produced by reacting diorganodichlorosilanes and monochlorosilanes and optionally dichlorosilanes with water in a first step, where at least one of the monochlorosilanes or dichlorosilanes contain Si—H groups to give a partial hydrolysate and gaseous hydrogen chloride, and in a second step, treating the partial hydrolysate with water to remove SiCl groups still present to form hydrochloric acid, and producing a hydrolysate containing the organopolysiloxanes.
US08546582B2	Sulfenamide, vulcanization accelerator containing the sulfenamide for rubber, and process for producing the vulcanization accelerator A sulfenamide vulcanization accelerator is provided that acts satisfactorily slowly on a vulcanization reaction, produces no carcinogenic nitrosamine, and is free from environmental hygiene problems such as bioaccumulation. Also provided is an N-alkyl-N-t-butylbenzothiazole-2-sulfenamide represented by formula [I]. The vulcanization accelerator is a vulcanization accelerator for rubber, containing this compound. Furthermore provided is a process for producing the vulcanization accelerator. wherein R represents methyl, ethyl, n-propyl, or n-butyl.
US08546578B2	Iodonium Cyclophanes for SECURE arene functionalization This disclosure relates to compounds, reagents, and methods useful in the synthesis of aryl fluorides, for example, in the preparation of 18F labeled radiotracers. For example, this disclosure provides universal “locked” aryl substituents that result in StereoElectronic Control of Unidirectional Reductive Elimination (SECURE) from diaryliodonium salts. The reagents and methods provided herein may be used to access a broad range of compounds, including aromatic compounds, heteroaromatic compounds, amino acids, nucleotides, and synthetic compounds.
US08546575B2	NIP thiazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydroge-nase-1 The present invention relates to NIP thiazole derivatives of formula (I) as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11-β-HSD-1) and the use of such compounds for the treatment and prevention of metabolic syndrome, diabetes, insulin resistance, obesity, lipid disorders, glaucoma, osteoporosis, cognitive disorders, anxiety, depression, immune disorders, hypertension and other diseases and conditions.
US08546570B2	Process for preparing cationic rhodium complexes A process is described for the synthesis of a cationic [rhodium diolefin phosphorus ligand] complex comprising the steps of: (a) reacting a rhodium-diolefin-1,3-diketonate and an acid in a ketone solvent, (b) adding a stabilising olefin to form a stabilised cationic rhodium compound, and (c) mixing a phosphorus ligand with the solution of the stabilised cationic rhodium compound to form a solution of the cationic [rhodium diolefin phosphorus ligand] complex. The solution may be used directly or the complex recovered. In one embodiment, the solution may be combined with a co-solvent and the ketone removed to give a new catalyst solution, from which the complex may be recovered.
US08546564B2	Inhibitors of fatty acid amide hydrolase Provided herein are compounds of formula (I) or pharmaceutically acceptable salts, solvates or prodrugs thereof, or mixtures thereof, wherein Z1, Z2, X1, X2, X3, R1, R2 R3, m and n are defined herein. Also provided are pharmaceutically acceptable compositions that include a compound of formula I and a pharmaceutically acceptable excipient. Also provided are methods for treating FAAH-mediated disorders comprising administering to a subject in need thereof a therapeutically effective amount of a compound or composition of the present invention.
US08546562B2	Substituted porphyrins The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
US08546561B2	Nano-catalytic-solvo-thermal technology platform bio-refineries Methods of making glucose and/or furfural from biomass require one or more supercritical fluids that may be used to process biomass, cellulose from the biomass, and/or xylose from the biomass. Examples of supercritical fluids for use in processing biomass include ethanol, water, and carbon dioxide at a temperature and pressure above the critical points for ethanol and carbon dioxide but at a temperature and/or pressure below that of the critical point for water. A supercritical fluid containing carbon dioxide and water may be used to convert cellulose to glucose or convert xylose to furfural. The fluid has a temperature and pressure above the critical point of carbon dioxide, but at least one of the temperature and pressure is below the critical point for water.
US08546560B2	Solvo-thermal hydrolysis of cellulose The invention relates to a process for hydrolyzing cellulose, comprising: (a) contacting cellulose with a fluid mixture comprising supercritical CO2 and sub-critical or near-critical water to form a reactant mixture at a first temperature and first pressure for a first time period, wherein a reaction occurs and forms one or more hydrolysis products; (b) quenching the reaction; and (c) recovering at least one hydrolysis product.
US08546557B2	Methods of making nucleoside tetraphosphate analogs The invention provides compounds and methods for making adenosine-ribofuranoside tetraphosphate compounds. The compounds are contemplated to have activity at the P2Y receptor and may be used in the treatment of medical disorders such as cystic fibrosis and upper respiratory disorders.
US08546556B2	Carbocyclic alpha-L-bicyclic nucleic acid analogs The present invention provides novel carbocyclic α-L-bicyclic nucleosides and oligomeric compounds comprising at least one of these carbocyclic α-L-bicyclic nucleosides. The carbocyclic α-L-bicyclic nucleosides are useful for enhancing one or more properties of the oligomeric compounds they are incorporated into including nuclease resistance.
US08546555B2	Cochleate compositions directed against expression of proteins Disclosed herein are novel siRNA-cochleate and morpholino-cochleate compositions. Also disclosed are methods of making and using siRNA-cochleate and morpholino-cochleate compositions.
US08546554B2	Lipid formulated compositions and methods for inhibiting expression of Serum Amyloid A gene The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a Serum Amyloid A (SAA) gene, and methods of using the dsRNA to inhibit expression of SAA.
US08546553B2	Prokaryotic RNAi-like system and methods of use Provided herein are methods for inactivating a target polynucleotide. The methods use a psiRNA having a 5′ region and a 3′ region. The 5′ region includes, but is not limited to, 5 to 10 nucleotides chosen from a repeat from a CRISPR locus immediately upstream of a spacer. The 3′ region is substantially complementary to a portion of the target polynucleotide. The methods may be practiced in a prokaryotic microbe or in vitro. Also provided are polypeptides that have endonuclease activity in the presence of a psiRNA and a target polynucleotide, and methods for using the polypeptides.
US08546552B2	TMPRSS2 for the diagnosis of prostate disease Described herein are methods, compositions and kits directed to the detection the 5′ portion of TMPRSS2 mRNA for the detection and diagnosis of prostate disease including prostate cancer and benign prostatic hyperplasia.
US08546549B2	Processes for the convergent synthesis of calicheamicin derivatives This invention describes processes for the convergent synthesis of calicheamicin derivatives, and similar analogs using bifunctional and trifunctional linker intermediates.
US08546547B2	Polymer conjugates of Box-A of HMGB1 and Box-A variants of HMGB1 The present invention relates to novel polymer conjugates of polypeptide variants of the HMGB1 high affinity binding domain Box-A (HMGB1 Box-A) or of a biologically active fragment of HMGB1 Box-A. Further, the invention relates to novel polymer conjugates of polypeptide variants of the HMGB1 high affinity binding domain Box-A (HMGB1 Box-A). Moreover, the present invention concerns the use of said polymer conjugates of polypeptide molecules of HMGB1 Box-A to diagnose, prevent, alleviate and/or treat pathologies associated with extracellular HMGB1 and/or associated with an increased expression of RAGE.
US08546545B2	Antibody to SOST peptide The present invention is directed to isolated polypeptides and antibodies suitable for producing therapeutic preparations, methods, and kits relating to bone deposition. One objective of the present invention is to provide compositions that improve bone deposition. Yet another objective of the present invention is to provide methods and compositions to be utilized in diagnosing bone dysregulation. The therapeutic compositions and methods of the present invention are related to the regulation of Wise, Sost, and closely related sequences. In particular, the nucleic acid sequences and polypeptides include Wise and Sost as well as a family of molecules that express a cysteine knot polypeptide.
US08546540B2	Antibody targeting osteoclast-related protein Siglec-15 To provide a method of detecting abnormal bone metabolism by using a gene strongly expressed in an osteoclast; a method of screening a compound having a therapeutic and/or preventive effect on abnormal bone metabolism; and a pharmaceutical composition for treating and/or preventing abnormal bone metabolism. Provision of a method of detecting abnormal bone metabolism by using the expression of human Siglec-15 gene as an index; a pharmaceutical composition containing an antibody which specifically recognizes human Siglec-15 and has an activity of inhibiting osteoclast formation; and the like.
US08546539B2	Fc receptor-binding polypeptides with modified effector functions Disclosed are processes for producing a variant polypeptide (e.g. antibodies) having modified binding characteristics for human Fc gamma receptor IIA (CD32A) leading to increased inhibition of proinflammatory mediators while retaining binding to a target antigen via its Fv portion, which processes comprise altering the polypeptides by substitution of at least two amino acid residues at EU position 325, 326 or 328 of a human IgG CH2 region for a sequence selected from SAAF, SKAF, NAAF and NKAF. Also disclosed are molecules, particularly polypeptides, more particularly immunoglobulins (e.g. antibodies) that include a variant CDR3 region, wherein the variant CDR3 region includes at least one amino acid modified relative to a wild-type CDR3 region. The polypeptides that can be generated according to the methods of the invention are highly variable, and they can include antibodies and fusion proteins that contain an Fc region or a biologically active portion thereof.
US08546537B2	Streptavidin having low immunogenicity and use thereof It is an object of the present invention to provide a mutant streptavidin wherein the immunogenicity (antigenicity) in mammals of a streptavidin is reduced. The present invention provides a mutant streptavidin, which comprises an amino acid sequence in which (a) the arginine residue at position 72 is substituted with another amino acid residue, and (b) any one or more of the tyrosine residue at position 10, the tyrosine residue at position 71, the glutamic acid residue at position 89, the arginine residue at position 91, and the glutamic acid residue at position 104 are substituted with other amino acid residues, with respect to the amino acid sequence of a core streptavidin as shown in SEQ ID NO: 2, and which has decreased immunogenicity as compared with that of a wild-type streptavidin.
US08546535B2	Lytic domain fusion constructs and methods of making and using same The invention relates to fusion constructs, methods of using fusion constructs and methods of treating undesirable or aberrant cell proliferation or hyperproliferative disorders, such as tumors, cancers, neoplasia and malignancies.
US08546531B2	Methods and reagents for preparing multifunctional probes Multifunctional probes are synthesized in a single step using peptide scaffold-based multifunctional single-attachment-point reagents. To obtain multifunctional probes using the methods of the invention, a substrate (e.g., a nanoparticle, polymer, antibody, protein, low molecular weight compound, drug, etc.) is reacted with a multifunctional single-attachment-point (MSAP) reagent. The MSAP reagents can include three components: (i) a peptide scaffold, (ii) a single chemically reactive group on the peptide scaffold for reaction of the MSAP with a substrate having a complementary reactive group, and (iii) multiple functional groups on the peptide scaffold. The peptide scaffold can include any number of residues; however, for ease of synthesis and reproducibility in clinical trials, it is preferred to limit the residues in the peptide to 20 or less. The reagent can be prepared to yield a predetermined stoichiometric ratio of the functional groups on the scaffold such that the probe has a fixed stoichiometric ratio of the functional groups.
US08546526B2	Selective αvβ3 receptor peptide antagonist for therapeutic and diagnostic applications The present invention is related to new peptide antagonists of αvβ3 receptor, designed on the basis of the crystal structure of integrin αvβ3 in complex with c(RGDf[NMe]V) and the NMR structure of echistatin. These peptides are potent and selective antagonists of the αvβ3 receptor and can be used as novel anticancer drugs and/or new class of diagnostic non-invasive tracers as suitable tools for αvβ3-targeted therapy and imaging.
US08546523B2	NPR-B agonists Disclosed are novel compounds having NPR-B agonistic activity. Preferred compounds are linear peptides containing 8-13 conventional or non-conventional L- or D-amino acid residues connected to one another via peptide bonds.
US08546521B2	Method for fabricating nanoparticles Systems and methods are provided for filtering a fluid containing nanoparticles. The systems and methods generally include introducing a stream of the nanoparticle-containing fluid into a holding vessel, and extracting at least a part of a nanoparticle-containing fluid accumulated in the holding vessel. The extracted nanoparticle-containing fluid is passed through a filtration module to separate a nanoparticle-containing retentate from a permeate, and the retentate is returned to the vessel. The filtration cycle can be repeated until a desired concentration of the nanoparticles is achieved in the holding vessel. In many embodiments, the generation of the nanoparticle-containing fluid and its filtration are performed concurrently.
US08546517B2	Poly(bisoxalamides) The present invention generally relates to a poly(bisoxalamide) and a process for preparing and article comprising the poly(bisoxalamide).
US08546516B2	Transparent polyimide-polyester compositions, method of manufacture, and articles thereof A thermoplastic polymer composition comprises a combination of: 40 to 60 pbw, of a polyetherimides, polyetherimide sulfones, or combination thereof having a weight average molecular weight from 5,000 to 80,000 Daltons; 40 to 60 pbw of a polyethylene terephthalate, the polyethylene terephthalate having a diethylene glycol content from 0.1 to 4 wt %, based on the weight of the polyethylene terephthalate, an intrinsic viscosity that is more than 0 and less than 0.83 dl/g, and carboxylic acid end groups in an amount from 10 to 150 meq/Kg; from 0 pbw to 1 pbw, based on 100 pbw of the polymer composition of a stabilizer selected from phenol-containing stabilizers, phosphorus-containing stabilizers, or a combination thereof; and, based on the weight of the polyethylene terephthalate, 10 to 300 antimony; 0 to 300 ppm of cobalt; and 0 to 300 ppm of titanium; wherein the polymer composition is bisphenol A free.
US08546514B2	Continuous process for manufacturing aliphatic polycarbonates from carbon dioxide and epoxides Disclosed is a continuous process for manufacturing aliphatic polycarbonate by polymerizing carbon dioxide and one or more epoxide compound in the presence of catalyst, in which carbon dioxide, one or more epoxide compound, and the catalyst are continuously supplied to polymerization reactor to produce aliphatic polycarbonate, separate unreacted carbon dioxide and epoxide compound and recycle them as raw materials.
US08546507B2	Silicone polyoxamide process additives for high clarity applications There is provided a silicone-polyoxamide process additive for use in high clarity applications, articles made using the silicone-polyoxamide process additive, and methods for making these articles.
US08546503B2	Method for controlling anionic polymerization This invention deals with an approach to control anionic polymerization. The anionic polymerization is conducted by adding a kind of initiator ligand compound, directly or in the form of solution into the monomer or initiator at the same or different time, or at different stages. The metal atoms in the ligand can form the association with the initiator cations, while the alkyloxy groups in the initiator ligand can restrict the entering channel of the addition of the monomers due to their relatively large volume or steric hindrance. Therefore, the initiator ligand compound can restrict the rate of anionic polymerization, restrain the side reaction, and make the anionic polymerization possible to be conducted at room or even higher temperature. The molar ratio of initiator ligand compound to initiator is from 0.01:1 to 20:1. Compared with present technologies, the method of this invention can control and adjust the homopolymerization and copolymerization rate, side reactions and the polymerization temperature, and make it possible to industrialize.
US08546501B2	Catalyst compounds and use thereof This invention relates to Group 4 catalyst compounds containing di-anionic tridentate nitrogen/oxygen based ligands. The catalyst compounds are useful, with or without activators, to polymerize olefins, particularly α-olefins, or other unsaturated monomers. Systems and processes to oligomerize and/or polymerize one or more unsaturated monomers using the catalyst compound, as well as the oligomers and/or polymers produced therefrom are also provided.
US08546498B2	Method for producing water-absorbing polymer particles by polymerizing droplets of a monomer solution A process for producing water-absorbing polymer particles by polymerizing droplets of a monomer solution in a surrounding gas phase in a reaction chamber, wherein the monomer solution is metered into the reaction chamber via at least one bore, and the diameter is from 210 to 290 μm per bore and the metering rate is from 0.9 to 5 kg/h per bore.
US08546497B2	Reactor for propylene polymerization and process for producing propylene polymer A propylene polymerization reaction apparatus and a production method of a propylene-based polymer are capable of producing a continuous multi-stage polymer in low cost, high productivity and stably, and significantly reducing generation amount of an off-specification product accompanying change of polymerization condition, in multi-stage continuous vapor phase polymerization method of a propylene-based polymer using a catalyst for olefin polymerization. A reaction apparatus for producing a propylene-based polymer by a multi-stage continuous vapor phase polymerization method is used. One or more reactor of a horizontal-type reactor having inside a stirring machine which rotates around a horizontal axis, and a continuous stirred tank reactor to be connected to the horizontal-type reactor are provided, and a production method of a propylene-based polymer using the same.
US08546496B2	Process for preparing a bimodal polyethylene product in a single loop reactor The present invention relates to a process for preparing a bimodal polyethylene product in a single loop reactor, comprising polymerizing ethylene monomer and optionally one or more olefin co-monomers in the presence of a single heterogeneous polymerization catalyst consisting of a metallocene-alumoxane catalyst immobilized on a porous support wherein said metallocene comprises only one transition metal. Said polymerization catalyst consists of two physically different fractions of support particles onto which said metallocene-alumoxane catalyst is immobilized.
US08546490B2	Injection molded article comprising polypropylene and polylactic acid A film comprising a polylactic acid and polypropylene blend having a haze of from about 10% to about 95% and a gloss 45° of from about 50 to about 125. A method of producing an oriented film comprising blending polypropylene and polylactic acid to form a polymeric blend, forming the polymeric blend into a film, and orienting the film. A method of producing an injection molded article comprising blending polypropylene and polylactic acid to form a polymeric blend, injecting the polymeric blend into a mold, and forming the article.
US08546487B2	Cationic poly (amino acids) and uses thereof The present invention provides an efficient delivery system for a nucleic acid, more specifically, a cationic poly(amino acid) that has a side chain having a plurality of different amine functional groups in a moiety including a cationic group and that has a hydrophobic group introduced into part of the side chain, and a polyion complex (PIC) of the poly(amino acid) and an oligo- or polynucleotide.
US08546486B2	Low VOC thermosetting polyester acrylic resin for gel coat Low VOC thermosetting polyester acrylic resins are made by esterification of unsaturated epoxide such as glycidyl methacrylate, and a polyacid which is the half-ester formed by reacting an acid or its anhydride with a polyol is disclosed. The obtained low viscosity resin is useful for making a low or zero VOC gel coat with excellent hydrolytic and weather resistance.
US08546484B2	UV-shielding silicone coating composition and coated article A UV-shielding silicone coating composition comprises (A) a dispersion in a dispersing medium of composite zinc oxide nanoparticles which are obtained by coating zinc oxide nanoparticles with an oxide or hydroxide of Al, Si, Zr or Sn, the dispersion having a photocatalytic degradability of up to 25%, (B) a silicone resin, (C) a curing catalyst, and (D) a solvent, the solids content of composite zinc oxide nanoparticle dispersion (A) being 1 to 50% by weight based on silicone resin (B). The composition is transparent to visible light, mar resistant, UV-shielding, weatherable, and durable.
US08546483B2	Oil-in-water organopolysiloxane emulsion composition, cosmetic ingredient comprising this composition, and method of producing a hair cosmetic using this composition To provide a highly storage-stable nonionic oil-in-water organosiloxane emulsion composition that substantially does not contain ionic surfactant and that on a long-term basis does not undergo separation of the emulsion composition. An oil-in-water organosiloxane emulsion composition that characteristically comprises (A) 100 weight parts of organosiloxane, (B) 0.5 to 35 weight parts of organic-modified organosiloxane, (C) 0.5 to 35 weight parts of nonionic surfactant, (D) 0.5 to 15 weight parts of water-soluble solvent, and (E) water, wherein the content of (F) ionic surfactant in the composition is less than 0.1 weight part per 100 weight parts component (A).
US08546482B2	Low odor compositions and low odor coating compositions This invention provides stable aqueous compositions including stable coating compositions, and methods of their production. The stable aqueous compositions and stable aqueous coating compositions comprise one or more emulsion-polymerized addition polymer, one or more carboxylesterase enzyme, and one or more carboxylesterase deactivating agent, such that the ester hydrolysis activity in the composition is less than 0.010 micromole/minute, and wherein the aqueous composition has a headspace volatile organic compound (VOC) content, as measured by headspace gas chromatography-mass spectrometry (GC-MS) at 33° C., of less than 10 ppm of organic carboxylester with a normal boiling point of less than 150° C. and more than 50 ppm of mono-alcohol with a formula molecular weight of less than 76. The carboxylesterase enzyme is employed to minimize the free carboxylester content in the composition, thereby providing a low odor composition, and the carboxylesterase is deactivated in situ in order to minimize the residual carboxylesterase enzyme activity.
US08546481B2	Aqueous dispersion containing polyolefin graft copolymer An aqueous dispersion containing a graft copolymer satisfying (a) to (e) and water: (a) a graft rate is 1 to 150% by mass, (b) a weight average molecular weight is 500 to 400000, (c) a molecular weight distribution is 1.5 to 4, (d) a main chain containing a monomer unit having a hydrophilic group and (e) an α-olefin homopolymerization or α-olefin/ethylene copolymerization side chain, wherein a mesopentad ratio [mmmm] of the polymerization chain is 30 to 80 mole %.
US08546478B2	Thermoplastic elastomer composition and method for producing the same Disclosed is a method for producing a thermoplastic elastomer composition having a phase structure comprising a continuous phase comprising at least one thermoplastic resin and a disperse phase comprising dynamically crosslinked elastomer particles finely dispersed in the continuous phase, the method being characterized by dispersing in at least one crosslinkable elastomer component furnace carbon black having a BET nitrogen adsorption specific surface area of from 100 to 260 m2/g and a primary particle average particle diameter of from 10 to 25 nm in an amount of 1 to 15 parts by weight with respect to 100 parts by weight of the at least one crosslinkable elastomer component, prior to or during dynamic crosslinking.
US08546475B2	Infrared reflecting black pigment, and paint and resin composition using the infrared reflecting black pigment The present invention provides an inexpensive infrared reflecting black pigment which comprises Fe and Mn but comprises no harmful elements, and exhibits an excellent infrared reflecting property. The infrared reflecting black pigment according to the present invention comprises a compound comprising Fe, Mn and at least one element selected from the group consisting of Mg, Al, Ca, Si, Sr and Ba, and has a blackness (L* value) of not more than 30 and a solar radiation reflectance of not less than 15%.
US08546472B2	Polyesters based on 2-methylsuccinic acid The present invention relates to a polyester comprising repeat units based on at least one aliphatic dicarboxylic acid or an ester-forming derivative thereof (component A1), at least one aromatic dicarboxylic acid or an ester-forming derivative thereof (component A2), at least one diol (component B), optionally at least one sulfo-containing compound (component A3) and optionally at least one trifunctional crosslinking agent as component C1 and/or at least one difunctional chain extender as component C2, component A1 comprising 2-methylsuccinic acid or an ester-forming derivative thereof, to a process for preparing the inventive polyester, to the mixtures comprising the inventive polyester, to the use of the inventive polyesters or of the inventive mixtures for production of moldings, films, adhesives, foams or fibers, and to moldings, films, adhesives, foams or fibers comprising at least one inventive polyester or at least one inventive mixture.
US08546469B2	Glass fiber-reinforced polyester resin composition and molded product using the same A glass fiber-reinforced polyester resin composition including: (A) about 30 to about 80 wt % of two or more kinds of polyester resin; (B) about 20 to about 70 wt % of a vinyl-based copolymer including an acrylic-based graft copolymer, a rubber modified vinyl-based graft copolymer, a copolymer of aromatic vinyl monomers and unsaturated nitrile monomers, or a combination thereof; and (C) about 10 to about 100 parts by weight of glass fiber, based on about 100 parts by weight of the total amount of the polyester resin (A) and the vinyl-based copolymer (B), wherein the polyester resin includes polyethylene terephthalate resin having crystallinity of about 40% or more, is provided.
US08546466B2	Image recording composition, ink set for image recording, recording apparatus, and image recording method According to the invention, there is provided an image recording composition comprising a curable material capable of immobilizing a colorant material in a received ink and curable by an external stimulus.
US08546465B2	Aqueous ink for inkjet An aqueous ink for an inkjet, comprising a pigment, a polymer compound that coats the pigment, a water-soluble organic solvent, and water, wherein the polymer compound has a β-diketone group and a cationic salt-forming group, and also includes a cross-linked structure based on a siloxane linkage.
US08546464B2	Rubber compositions including metal-functionalized polyisobutylene derivatives and methods for preparing such compositions A composition includes a vulcanizable diene rubber, a silica filler, and a metal-functionalized polyisobutylene succinic anhydride derivative. In one embodiment the composition has a reduced amount of oil and may include no oil. A tire tread composition includes, a silica filler, a metal-functionalized polyisobutylene succinic anhydride derivative, a rubber matrix, an optional oil, and one or more components selected from the group consisting of carbon black, vulcanizing agent, vulcanization accelerator, tackifier resin, antioxidant, wax, peptizer, vulcanization retarder, activator, processing additive, plasticizer, pigments, and antiozonant. A method for making the rubber composition and the tire tread is also provided.
US08546462B2	Bone cement system for bone augmentation A bone cement is provided that includes a solid component and a liquid component. The solid component and liquid component are mixed together to form the bone cement. After completion of the solid and liquid component mixing, the bone cement has an initial viscosity effective for manual application or manual injection onto or into a targeted anatomical location, e.g., bone, and the cement has stable viscosity range that over both time and temperature is effective for uniformly filling the targeted anatomical location, for example an osteoporotic bone or a fractured vertebral body, with minimal to no leakage of the cement from the targeted anatomical location. Additionally, both the initial viscosity and the stable viscosity of the bone cement are within a range that renders the bone cement effective for injection with a manually operated syringe or multiple syringes.
US08546459B2	Dental filling/restoration kit Provided is a filling/restoring material, including a photopolymerization initiator of a quaternary system formed by combining an α-diketone compound, an aliphatic amine compound, an aromatic amine compound, and a photoacid generator, in which even when the filling/restoring material is filled and cured on a cured layer of a dental adhesive material including a radical-polymerizable monomer having an acidic group, the filling/restoring material undergoes sufficient curing up to a contact interface between the filling/restoring material and the cured layer, thereby providing high adhesive strength stably. Also provided is a dental filling/restoration kit, including: a filling/restoring material including: a polymerizable monomer having no acidic group; a basic inorganic material; and a photopolymerization initiator formed by at least combining: an α-diketone compound; an aliphatic amine compound; an aromatic amine compound; and a photoacid generator; and an adhesive material, which is used for adhesion between a tooth and the filling/restoring material by curing the adhesive material before filling the filling/restoring material, the adhesive material including: a polymerizable monomer including a polymerizable monomer having an acidic group; and a polymerization initiator.
US08546450B1	Treatment of pain with topical diclofenac compounds The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.
US08546449B2	Methods and compositions for the generation of peracetic acid on site at the point-of-use Methods and compositions for the generation of a peroxyacetic acid sanitizer in proximity to the point-of-use are disclosed. These methods comprise introducing a hydrogen peroxide-acetyl precursor solution to water, mixing, and then adding an aqueous source of a alkali metal or earth alkali metal hydroxide. Triacetin is a preferred acetyl precursor and is converted rapidly and with a high conversion rate into peracetic acid. These methods produce solutions with a high level of peracetic acid. Methods for preparing the hydrogen peroxide-acetyl precursor solution are also provided. Also disclosed are solid compositions comprising a liquid acetyl precursor, a water-soluble source of hydrogen peroxide, and a water-soluble source of alkalinity. The solid composition is a freely-flowable solid that is used as a bleaching agent and a stain remover for the treatment of articles such as fabrics, dentures, textile garments, and equipment used in the food and beverage industry.
US08546447B2	Treatment of acne using derivatives of 5-aminolevulinic acid The invention provides use of a photosensitiser, which is a derivative (e.g., an ester) of 5-aminolevulinic acid (5-ALA) or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for use in the prevention or treatment of acne.
US08546446B2	Anionic isosorbide derivatives and their use Disclosed are isosorbide derivatives according to the following general formula wherein R represent a hydrogen atom, or an alkyl group with 6 to 22 C-atoms, or an acyl group, or a group X—SO3M, and M stands for a cation, a hydrogen atom or an alkali metal atom or an ammonium or an alkylammonium ion, and X represents an alkoxylated derivative (AO)n wherein AO represents a group C2H4O, or C3H6O, or any mixtures thereof, and the index n is zero or 1 to 20, and p represents a number between 1 and 10, preferably between 1 and 4, and the use thereof to prepare cleansers, detergents, personal care compositions, or cosmetic compositions.
US08546432B2	Tetrazolones as inhibitors of fatty acid synthase Provided herein are tetrazolone FASN inhibitors of the formula (I): or a pharmaceutically acceptable form thereof; wherein the variables RA, RB and RC are defined herein. Also provided herein are pharmaceutical compositions of the compounds provided herein as well as methods of their use for the treatment of various disorders such as hyperproliferative disorders, inflammatory disorders, obesity-related disorders and microbial infections.
US08546425B2	Folate receptor binding conjugates of antifolates Conjugates of antifolates, releasable linkers, and drugs, and pharmaceutical compositions containing them are described. The conjugates are useful for treating diseases arising from pathogenic cell populations. Methods for treating such diseases are also described.
US08546422B2	Azaindole derivatives as CRTH2 receptor antagonists Compounds of formula I are antagonists of the PGD2 receptor, CRTH2, and as such are useful in the treatment and/or prevention of CRTH2-mediated diseases such as asthma.
US08546420B2	4, 5-ring annulated indole derivatives for treating or preventing of HCV and related viral infections The present invention relates to 4,5-ring annulated indole derivatives of formula (I), compositions comprising at least one 4,5-ring annulated indole derivatives, and methods of using the 4,5-ring annulated indole derivatives for treating or preventing a viral infection or a virus-related disorder in a patient, wherein ring Z of formula (I), is cyclohexyl, cyclohexenyl, 6-membered heterocycloalkyl, 6-membered heterocycloalkenyl, 6-membered aryl or 6-membered heteroaryl, wherein R1, R2, R3, R6, R7 and R10 are as described herein.
US08546418B2	Peripheral opioid receptor antagonists and uses thereof The present invention provides a compound of formula I: wherein R1, R2, R2′ and X′ are as defined and described herein, methods of manufacture thereof and compositions thereof, useful for example as peripheral mu opioid receptor antagonists in treatment of side effects of opioid administration.
US08546415B2	Bis-pyridino containing compounds for the use in the treatment of CNS pathologies N-n-Alkylation of nicotine converts nicotine from an agonist into an antagonist specifically for neuronal nicotinic acetylcholine receptor subtypes mediating nicotine-evoked dopamine release. Conformationally restricted analogs exhibit both high affinity and selectivity at this site, and are able to access the brain due to their ability to act as substrates for the blood-brain barrier choline transporter.
US08546414B2	Ion channel modulators and methods of use In general, the invention relates to novel 4-phenylpyrimidine compounds useful as ion channel modulators. It has now been found that compounds of this invention, and pharmaceutically acceptable compositions thereof, are useful as inhibitors of voltage-gated sodium channels and/or calcium channels for the treatment of pain.
US08546408B2	Fused heteroaryl pyridyl and phenyl benzenesuflonamides as CCR2 modulators for the treatment of inflammation Fused heteroaryl pyridyl benzenesulfonamides are provided that act as potent antagonists of the CCR2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases and as controls in assays for the identification of CCR2 antagonists.
US08546406B2	Heterocyclic compounds as metap-2 inhibitors Compounds of the formula I, in which D, X, Y, Z, R and R1 have the meanings indicated in Claim 1, are inhibitors of methionine aminopeptidase and can be employed for the treatment of tumors.
US08546404B2	Compounds that are ERK inhibitors Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, esters and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
US08546403B2	Compounds that modulate intracellular calcium Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
US08546401B2	5,6-disubstituted oxindole-derivatives and use thereof for treating vasopressin-dependent diseases The present invention relates to novel 5,6-disubstituted oxindole derivatives and pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising such derivatives, and to the use of such derivatives for the manufacture of a medicament, and methods of treating disorders in a subject in need thereof, such as vasopressin-dependent disorders, using 5,6-disubstituted oxindole derivatives.
US08546400B2	1,3-Oxazole-4-carboxamides, 1,3-Thiazole-4-carboxamides, and 1,3-Imidazole-d-carboxamides as Inhibitors of cyclin Dependent kinases Oxazole derivatives are described. The inventive compounds are useful as kinase inhibitors, and may be used in the treatment of cancer, such as prostate cancer, lung cancer, breast cancer, colon cancer, leukemia, CNS cancer, melanoma, ovarian cancer, and renal cancer.
US08546397B2	DNA methylation inhibitors A number of DNA methylation inhibitors are described. The DNA methylation inhibitors were identified using a two-component enhanced green fluorescent protein reporter system to screen a compound library containing procainamide derivatives. The DNA methylation inhibitors can be used for cancer therapy and prevention.
US08546396B2	N-(hetero)aryl, 2-(hetero)aryl—substituted acetamides for use as Wnt signaling modulators The present invention relates to compounds of formulae 1 and 2 and methods for modulating the Wnt signaling pathway using these compounds, wherein A1, A2, B, Y and Z all represent rings.
US08546393B2	6-triazolopyridazine sulfanyl benzothiazole derivatives as MET inhibitors The disclosure relates to compounds of formula (I): wherein , A, W, X, and Ra are as defined in the disclosure, and salts thereof, and to pharmaceutical compositions comprising said compounds, to processes for preparing them, and to their use as medicaments, in particular as MET inhibitors.
US08546386B2	Corrosion and microbial control in hydrocarbonaceous compositions Provided are additives of formula I for use in hydrocarbonaceous compositions, such as petroleum or liquid fuels: (I) wherein R1, R2, R3, R4, and R5 are as defined herein. The additives improve the corrosion resistance of the compositions. The additives also enhance the antimicrobial efficacy of any added biocides contained in such compositions.
US08546381B2	Bridged heterocyclic compounds and methods of use This disclosure relates to new compounds that may be used to modulate a histamine receptor in an individual. Novel compounds are described, including new bridged heterocyclic [4,3-b]indole compounds. Pharmaceutical compositions are also provided. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder.
US08546380B2	Aminodihydrothiazine derivatives A composition having BACE 1 inhibitory activity containing a compound represented by the formula (I): wherein ring A is an optionally substituted heterocyclic group; E is lower alkylene; X is S; R1 is a hydrogen atom or lower alkyl; R2a, R2b, R3a, R3b, R4a and R4b is each independently a hydrogen atom, halogen, or hydroxy etc.; n and m are each independently an integer of 0 to 3; n+m is an integer of 0 to 3; R5 is a hydrogen atom or substituted lower alkyl; or its pharmaceutically acceptable salt thereof.
US08546375B2	(3-(4-(aminomethyl)phenoxy or phenylthio)azetidin-1-yl)(5-phenyl-1,3,4-oxadiazol-2-yl)methanone compounds Disclosed herein are azetidinyl compounds of formula I, as described herein, pharmaceutical compositions comprising an azetidinyl compound, and a method of using an azetidinyl compound in the treatment or prophylaxis of a melanin-concentrating hormone related disease or condition.
US08546374B2	Amino-tetrazoles analogues and methods of use A compound having Formula (I) or Formula (II) is disclosed as an P2X7 antagonist, wherein A, B, C, Y, Y, Z, m, v, R1, R2, R3, R4, and R5, are as defined in the description. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.
US08546372B2	Methods of treating hypertriglyceridemia In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
US08546371B2	Nanoparticle formulated glycolipid antigens for immunotherapy A composition for stimulating NKT cells to produce anti-cancer and anti-viral cytokines without causing anergy of NKT cells includes a glycolipid antigen and a nanoparticle conjugated with the glycolipid antigen. The glycolipid antigen and the nanoparticle are not antigenic in mouse and human being. The composition can further include covalent or non-covalent connection between the glycolipid antigen and the nanoparticle. The glycolipid antigen is alpha-galactosylceramide or an analog of that. The nanoparticle can be a polymer. A production method of the composition includes preparing a nanoparticle and a glycolipid antigen and loading the glycolipid antigen to the nanoparticle. The glycolipid antigen can be coated onto the surface of the nanoparticle or encapsulated within the nanoparticle. A method of stimulating NKT cells to produce anti-cancer and anti-viral cytokines without causing anergy of NKT cells is also provided.
US08546370B2	Compounds and compositions as kinase inhibitors The invention provides a novel class of 2,7-naphthyridin derivatives; pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly Syk, ZAP70, KDR, FMS, FLT3, c-Kit, RET, TrkA, TrkB, TrkC-GR-1R, Alk, c-FMS, or combinations thereof.
US08546366B2	Method for inhibition of tumor cell growth using (22R)-5α-lanosta-8,24-dien-3β,15α,21-triol In this patent, we isolated a novel compound from fruiting body of Antrodia cinnamomea, namely, (22R)-5α-lanosta-8,24-dien-3β,15α,21-triol. This compound possesses preferential cytotoxicity against human leukemia, pancreatic cancer, esophageal cancer, hepatoma, and cervical cancer cells.
US08546365B2	Bile acid derivatives as FXR ligands for the prevention or treatment of FXR-mediated diseases or conditions The present invention relates to compounds of formula (I): wherein R is hydrogen or alpha-hydroxy, the hydroxyl group in position 7 is in the alpha or beta position; and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof.
US08546358B2	Method of treating asthma The present invention is directed to a method for treating or ameliorating asthma in a subject in need thereof comprising administering to the subject a therapeutically effective amount of compound 17:
US08546355B2	Compositions comprising cyclodextrin A stable composition for removing unwanted molecules from a surface comprises functionally-available cyclodextrin, cyclodextrin-compatible surfactant, and cyclodextrin-incompatible surfactant. The compositions are suitable for capturing unwanted molecules from inanimate surfaces, including fabrics, including carpets, and hard surfaces including countertops, dishes, floors, garbage cans, ceilings, walls, carpet padding, air filters, and the like, and from animate surfaces, including skin, hair, and the like. The compositions can further comprise other cyclodextrin-compatible and -incompatible materials and other optional ingredients.
US08546349B2	siRNA targeting VEGFA and methods for treatment in vivo Vascular endothelial growth factor A (VEGFA) is a chemical signal produced by cells that stimulates the growth of new blood vessels, and overexpression of VEGFA can lead to undesirable physiological conditions. Through the identification of new siRNA and modifications that improve the silencing ability of these siRNA in vivo, therapeutic compositions and methods have been invented to address the problems associated with this overexpression.
US08546348B2	Upregulation of opioid receptors for management Disclosed are methods for treating pain in a subject. The method includes upregulating expression of opioid receptors in the subject's dorsal root ganglion or trigeminal neurons. Also disclosed are methods of treating neuropathic and/or chronic pain in a subject. The method includes upregulating expression of μ-opioid or δ-opioid receptors in the subject's dorsal root ganglion or trigeminal neurons.
US08546347B2	Composition for treatment and improvement of diabetes comprising caveolin as active ingredient and a method for treatment of diabetes using it The present invention relates to a composition for the treatment and improvement of diabetes comprising caveolin as an active ingredient and a method for treating diabetes using the same, more precisely a composition comprising caveolin-1 as an active ingredient for the treatment and improvement of type II diabetes which is age-dependent but not showing obesity symptom and a method for treating diabetes using the same. The treatment method and composition of the present invention is very effective in improving and treating diabetes by regulating insulin sensitivity by increasing caveolin level in muscle tissues of type II diabetes patient which is age-dependent but not showing obesity symptom.
US08546343B2	Aminoglycoside antibiotics targeting bacterial 16S ribosomal RNA The present invention relates to paromamine-based compounds according to formula I having selective antimicrobial activity directed at ribosomal 16S RNA. Furthermore, the invention is directed to the use of said compounds for preparing a medicament, pharmaceutical preparations and methods for preparing said compounds.
US08546337B2	Self-assembling peptide nanoparticles useful as vaccines Self-assembling peptide nanoparticles (SAPN) incorporating T-cell epitopes and/or B-cell epitopes are described. The nanoparticles of the invention consist of aggregates of a continuous peptidic chain comprising two oligomerization domains connected by a linker segment wherein one or both oligomerization domains incorporate T-cell epitopes and/or B-cell epitopes within their peptide sequence. These nanoparticles are useful as vaccines and adjuvants.
US08546335B2	Peptidic hydrolyzate proteasome activators and compositions containing same The present invention concerns a peptidic hydrolyzate enriched in bioactive peptides, said hydrolyzate being a proteasome activator. Further, the present invention concerns a cosmetic or pharmaceutical composition comprising said hydrolyzate in a physiologically acceptable medium and also its use in treating signs of aging or photo-aging in skin and protecting the skin against challenges by ultraviolet radiation. Finally, the invention concerns a cosmetic treatment method intended to treat the signs of skin aging and photo-aging.
US08546332B2	Factor VIII polypeptide having factor VIII:C activity Factor VIII polypeptides having FVIII:C activity that contain modifications in the A3 and/or C1 and/or C2 domains of the sequence of the light chain of Factor VIII, characterized by the binding affinity to low density lipoprotein receptor protein, and methods for producing the same.
US08546331B2	Modulation of pathogenic CD14+/CD16+ monocytes The invention is based on the discovery that interleukin-1 alpha (IL-1alpha) is expressed on the proinflammatory CD14+CD16+ monocyte subset. Importantly, since IL-1alpha appears to be almost exclusively expressed on this monocyte subset and not other leukocytes, it represents an ideal marker for targeting the CD14+CD16+ monocyte subset. The effectiveness of an agent that depletes such pathogenic cells or modulates IL-1alpha function on such cells type can be monitored by assessing CD14+CD16+ monocyte levels or functionality.
US08546328B2	Liquid formulation of G-CSF conjugate The present invention relates to a liquid pharmaceutical composition comprising a granulocyte colony stimulating factor polypeptide conjugated with a polymer, the composition having a pH value in the range of 4.5 to 5.5. The composition further comprises a surfactant and optionally one or more other pharmaceutically acceptable excipients. Further, the composition of the invention is free from tartaric acid or salts thereof and from succinic acid and salts thereof as buffering agents and does not contain amino acids as stabilizer. The composition has a good storage stability and is especially useful for the prophylaxis and treatment of disorders and medical indications where granulocyte colony stimulating factor preparations are considered as useful remedies.
US08546327B2	Glucagon/GLP-1 receptor co-agonists Modified glucagon peptides are disclosed having enhanced potency at the glucagon receptor relative to native glucagon. Further modification of the glucagon peptides by forming intramolecular bridges or the substitution of the terminal carboxylic acid with an amide group produces peptides exhibiting glucagon/GLP-1 receptor co-agonist activity. The solubility and stability of these high potency glucagon analogs can be further improved by modification of the polypeptides by pegylation, acylation, alkylation, substitution of carboxy terminal amino acids, C-terminal truncation, or the addition of a carboxy terminal peptide selected from the group consisting of SEQ ID NO: 26 (GPSSGAPPPS), SEQ ID NO: 27 (KRNRNNIA) and SEQ ID NO: 28 (KRNR).
US08546322B2	Inhibitors of intracellular urokinase plasminogen activator and methods of use thereof The present invention provides compositions comprising amiloride amino acid and peptide conjugates. Efficient methods are also provided for administering the compositions for treating cancer and for delivering an amiloride conjugate into cancer cells in a subject in need thereof.
US08546313B1	Nanotubular titania for decontamination of chemical warfare agents and toxic industrial chemicals The invention relates to methods and products enabling decontamination of chemical warfare agents and/or toxic industrial chemicals. More particularly, the invention pertains to improvements of surface decontamination processes using novel sorbents such as nanotubular titania.
US08546308B2	Triple tag sequences and methods of use thereof The present disclosure relates to novel triple tag sequences that may comprise a 6× histidine tag, a c-myc tag and a V5 tag. The present disclosure also provides polynucleotides, proteins, vectors and host cells that comprise the triple tag sequence of the present disclosure, including libraries of such polynucleotides, proteins, vectors and host cells. The novel triple tag sequences of the present disclosure may be used in phage display vectors and phage libraries and in methods for detection, screening, capture, purification, quantitation, and/or recovery of proteins of interest to which they are linked. Proteins of interest include antibodies such as single chain antibodies, single chain antibodies, and Fab fragments of antibodies or peptides such as non-antibody peptides.
US08546301B2	On-demand printable construct Multi-ply thermally printable constructs include a thermal print medium sandwiched between two opaque substrates that are temporarily bonded together to prevent information that is thermally printed through one of the substrates from being viewed until the substrates are separated. The thermal print medium, opaque substrates, and the means for bonding the substrates can take various forms for achieving particular objectives.
US08546297B2	Method for preparing an epoxidation catalyst A process for the preparation of a catalyst useful for the vapor phase production of ethylene oxide from ethylene and oxygen comprising the steps of providing a catalyst precursor comprising an inert support having a catalytically effective amount of a silver containing compound, a promoting amount of an alkali metal containing compound, and a promoting amount of a transition metal containing compound disposed thereon; and heating the catalyst precursor in a gas atmosphere for a first period of time and a second period of time, wherein for the first period of time the gas atmosphere is an inert gas atmosphere and the temperature range is from about 25° C. to about 600° C., and then in a second period of time the gas atmosphere is an oxygen-containing atmosphere and the second period temperature range is from about 350° C. to about 600° C.
US08546289B2	Solid catalyst component for olefin polymerization, catalyst for olefin polymerization and process for producing olefin polymer A solid catalyst component for olefin polymerization in which the molar ratio of residual alkoxy groups to supported titanium is 0.60 or less is obtained by reacting the following compound (a1) with the following compound (b1) at a hydroxyl group/magnesium molar ratio of 1.0 or more, reacting the reaction mixture with the following compound (c1) at a halogen/magnesium molar ratio of 0.20 or more, reacting the resultant reaction mixture with the following compounds (d1) and (e) at a temperature of 120° C. or higher but 150° C. or lower, washing the reaction mixture with an inert solvent, reacting the reaction mixture with the following compound (e) again at the above temperature and washing the reaction mixture with an inert solvent, whereby there can be provided the solid catalyst component for olefin polymerization and a catalyst for olefin polymerization which have high polymerization activity and give an olefin polymer having a less residual Cl content and being excellent in stereoregularity and powder form and a process for producing an olefin polymer, (a1) an oxide of at least one element that is selected from Group II to Group IV elements and which supports an alcohol-free halogen-containing magnesium compound, (b1) an alcohol, (c1) a halogen-containing silicon compound, (d1) an electron-donating compound, and (e) a halogen-containing titanium compound.
US08546286B2	Preparation of hydrogenation and dehydrogenation catalysts In a process for producing a metal containing catalyst composition suitable for effecting hydrocarbon hydrogenation and/or dehydrogenation reactions, a catalyst support comprising a porous crystalline material combined with an amorphous binder is treated with an anchoring material capable of bonding to the surface of the support and to a metal component. In addition, a precursor to the metal component is deposited on the surface of the catalyst support and then the treated catalyst support having the precursor deposited thereon is subjected to conditions effective to convert the precursor to the metal component and to cause the anchoring material to bond to the surface of the support and to the metal component.
US08546285B2	Nanostructured composite material of stabilized zirconia with cerium oxide and doped alumina with zirconia, use, and procedure for obtaining same The present invention provides a nanostructured composite material of γ-alumina-doped zirconia stabilised with cerium oxide and zirconia-doped α-alumina, the process for obtaining it and the applications thereof, such as knee prostheses, hip prostheses, dental implants, mechanical components for pumps, alkaline batteries, ceramic components for stereotactic neurology, cutting tools, etc.
US08546275B2	Atomic layer deposition of hafnium and zirconium oxides for memory applications Embodiments of the invention generally relate to nonvolatile memory devices and methods for manufacturing such memory devices. The methods for forming improved memory devices, such as a ReRAM cells, provide optimized, atomic layer deposition (ALD) processes for forming a metal oxide film stack having a metal oxide buffer layer disposed on or over a metal oxide bulk layer. The metal oxide bulk layer contains a metal-rich oxide material and the metal oxide buffer layer contains a metal-poor oxide material. The metal oxide bulk layer is less electrically resistive than the metal oxide buffer layer since the metal oxide bulk layer is less oxidized or more metallic than the metal oxide buffer layer. In one example, the metal oxide bulk layer contains a metal-rich hafnium oxide material and the metal oxide buffer layer contains a metal-poor zirconium oxide material.
US08546274B2	Interlayer dielectric material in a semiconductor device comprising stressed layers with an intermediate buffer material A highly stressed dielectric material, such as a tensile stressed material, may be deposited in a conformal manner so as to respect any deposition constraints caused by pronounced surface topography of highly scaled semiconductor devices, followed by the deposition of a buffer material having enhanced gap-filling capabilities. Thereafter, a further stress-inducing layer is deposited to form a doublet structure, which acts on the transistor elements, thereby enhancing overall performance, without increasing the probability of creating deposition-related irregularities. Hence, production yield as well as performance of highly scaled semiconductor devices may be increased.
US08546270B2	Atomic layer deposition apparatus An atomic layer deposition apparatus and an atomic layer deposition method increase productivity. The atomic layer deposition apparatus includes a reaction chamber, a heater for supporting a plurality of semiconductor substrates with a given interval within the reaction chamber and to heat the plurality of semiconductor substrates and a plurality of injectors respectively positioned within the reaction chamber and corresponding to the plurality of semiconductor substrates supported by the heater. The plurality of injectors are individually swept above the plurality of semiconductor substrates to spray reaction gas.
US08546266B2	Plasma processing method and plasma processing apparatus The invention provides a plasma processing apparatus and a dry etching method for etching a multilayered film structure having steps with high accuracy. The plasma processing apparatus comprises a vacuum reactor 107, a lower electrode 113 placed within a processing chamber of the vacuum reactor and having a wafer 112 to be etched mounted on the upper surface thereof, bias supplying units 118 and 120 for supplying high frequency power for forming a bias potential to the lower electrode 113, a gas supply means 111 for feeding reactive gas into the processing chamber, an electric field supplying means 101 through 103 for supplying a magnetic field for generating plasma in the processing chamber, and a control unit 127 for controlling the distribution of ion energy in the plasma being incident on the wafer 112 via the high frequency power.
US08546265B2	Method, apparatus and program for manufacturing silicon structure A method for manufacturing a silicon structure according to the present invention includes, in a so-called dry-etching process wherein gas-switching is employed, the steps of: etching a portion in the silicon region at a highest etching rate under a high-rate etching condition such that the portion does not reach the etch stop layer; subsequently etching under a transition etching condition in which an etching rate is decreased with time from the highest etching rate in the high-rate etching condition; and thereafter, etching the silicon region under a low-rate etching condition of a lowest etching rate in the transition etching condition.
US08546263B2	Method of patterning of magnetic tunnel junctions Embodiments of the invention generally relate to methods for fabricating devices on semiconductor substrates. More specifically, embodiments of the invention relate to methods of patterning magnetic materials. Certain embodiments described herein use a reducing chemistry containing a hydrogen gas or hydrogen containing gas with an optional dilution gas at temperatures ranging from 20 to 300 degrees Celsius at a substrate bias less than 1,000 DC voltage to reduce the amount of sputtering and redeposition. Exemplary hydrogen containing gases which may be used with the embodiments described herein include NH3, H2, CH4, C2H4, SiH4, and H2S. It has been found that patterning a magnetic tunnel junction with an oxidizer-free gas mixture comprising hydrogen maintains the integrity of the magnetic tunnel junction without producing harmful conductive residue.
US08546260B2	Fabric containing non-crimped fibers and methods of manufacture A chemical-mechanical planarization pad for semiconductor manufacturing is provided. The pad comprises synthetic fibers that are non-crimped fibers which are present in an amount of 1.0% by weight to 98.0% by weight in the mat and wherein the non-crimped fibers have a length of 0.1 cm to 127 cm and a diameter of 1.0 to 1000 micrometers.
US08546259B2	Nickel silicide formation for semiconductor components Semiconductor components are often fabricated that include a nickel silicide layer, e.g., as part of a gate electrode in a transistor component, which may be formed by forming a layer of nickel on a silicon-containing area of the semiconductor substrate, followed by thermally annealing the semiconductor substrate to produce a nickel silicide. However, nickel may tend to diffuse into silicon during the thermal anneal, and may form crystals that undesirably increase the sheet resistance in the transistor. Carbon may be placed with the nickel to serve as a diffusion suppressant and/or to prevent nickel crystal formation during thermal annealing. Methods are disclosed for utilizing this technique, as well as semiconductor components formed in accordance with this technique.
US08546258B2	Method of fabricating metal contact using double patterning technology and device formed thereby Metal contacts are formed within a string overhead area using a double patterning technology (DPT) process thereby allowing for the reduction of a string overhead area and a concomitant reduction in the chip size of a semiconductor device. A first mask pattern is formed by etching a first mask layer, the first mask pattern including a first opening formed in a cell region and a first hole formed in a peripheral region. A first sacrificial pattern is formed on the first mask pattern and the exposed first insulating layer of the cell region using a double patterning technology process. Contact holes are formed by exposing the target layer by etching the first insulating layer using the first mask pattern and the first sacrificial pattern as an etch mask. Metal contacts are then formed in the contact holes.
US08546257B2	Electrode arrays and methods of fabricating the same using printing plates to arrange particles in an array Electrode arrays and methods of fabricating the same using a printing plate to arrange conductive particles in alignment with an array of electrodes are provided. In one embodiment, a semiconductor device comprises: a semiconductor topography comprising an array of electrodes disposed upon a semiconductor substrate; a dielectric layer residing upon the semiconductor topography; and at least one conductive particle disposed in or on the dielectric layer in alignment with at least one of the array of electrodes.
US08546256B2	Method of forming semiconductor device The methods include forming a semiconductor substrate pattern by etching a semiconductor substrate. The semiconductor pattern has a first via hole that exposes side walls of the semiconductor substrate pattern, and the side walls of the semiconductor substrate pattern exposed by the first via hole have an impurity layer pattern. The methods further include treating upper surfaces of the semiconductor substrate pattern, the treated upper surfaces of the semiconductor substrate pattern being hydrophobic; removing the impurity layer pattern from the side walls of the semiconductor substrate pattern exposed by the first via hole; forming a first insulating layer pattern on the side walls of the semiconductor substrate pattern exposed by the first via hole; and filling a first conductive layer pattern into the first via hole and over the first insulating layer pattern.
US08546252B2	Metal gate FET having reduced threshold voltage roll-off A structure and method to create a metal gate having reduced threshold voltage roll-off. A method includes: forming a gate dielectric material on a substrate; forming a gate electrode material on the gate dielectric material; and altering a first portion of the gate electrode material. The altering causes the first portion of the gate electrode material to have a first work function that is different than a second work function associated with a second portion of the gate electrode material.
US08546248B2	Method of forming polycrystalline silicon layer and atomic layer deposition apparatus used for the same A method of forming a polycrystalline silicon layer and an atomic layer deposition apparatus used for the same. The method includes forming an amorphous silicon layer on a substrate, exposing the substrate having the amorphous silicon layer to a hydrophilic or hydrophobic gas atmosphere, placing a mask having at least one open and at least one closed portion over the amorphous silicon layer, irradiating UV light toward the amorphous silicon layer and the mask using a UV lamp, depositing a crystallization-inducing metal on the amorphous silicon layer, and annealing the substrate to crystallize the amorphous silicon layer into a polycrystalline silicon layer. This method and apparatus provide for controlling the seed position and grain size in the formation of a polycrystalline silicon layer.
US08546246B2	Radiation hardened transistors based on graphene and carbon nanotubes Graphene- and/or carbon nanotube-based radiation-hard transistor devices and techniques for the fabrication thereof are provided. In one aspect, a method of fabricating a radiation-hard transistor is provided. The method includes the following steps. A radiation-hard substrate is provided. A carbon-based material is formed on the substrate wherein a portion of the carbon-based material serves as a channel region of the transistor and other portions of the carbon-based material serve as source and drain regions of the transistor. Contacts are formed to the portions of the carbon-based material that serve as the source and drain regions of the transistor. A gate dielectric is deposited over the portion of the carbon-based material that serves as the channel region of the transistor. A top-gate contact is formed on the gate dielectric.
US08546244B2	Method of manufacturing semiconductor device A method includes the steps of: (a) fixing a front surface of a wafer (semiconductor wafer) having the front surface, a plurality of chip regions formed on the front surface, a dicing region formed between the chip regions, and a rear surface opposite to the front surface to the supporting member; (b) in a state of having the wafer fixed to the supporting member, grinding the rear surface of the wafer to expose the rear surface; (c) in a state of having the wafer fixed to the supporting member, dividing the wafer into the chip regions; (d) etching side surfaces of the chip regions to remove crushed layers formed in the step (c) on the side surfaces and obtain a plurality of semiconductor chips. After the steps (e) and (d), the plurality of divided chip regions are peeled off from the supporting member to obtain a plurality of semiconductor chips.
US08546243B2	Dual contact trench resistor and capacitor in shallow trench isolation (STI) and methods of manufacture A resistor and capacitor are provided in respective shallow trench isolation structures. The method includes forming a first and second trench in a substrate and forming a first insulator layer within the first and second trench. The method includes forming a first electrode material within the first and second trench, on the first insulator layer, and forming a second insulator layer within the first and second trench and on the first electrode material. The method includes forming a second electrode material within the first and second trench, on the second insulator layer. The second electrode material pinches off the second trench. The method includes removing a portion of the second electrode material and the second insulator layer at a bottom portion of the first trench, and filling in the first trench with additional second electrode material. The additional second electrode material is in electrical contact with the first electrode material.
US08546242B2	Hybrid gap-fill approach for STI formation A method of forming a shallow trench isolation region is provided. The method includes providing a semiconductor substrate comprising a top surface; forming an opening extending from the top surface into the semiconductor substrate; performing a conformal deposition method to fill a dielectric material into the opening; performing a first treatment on the dielectric material, wherein the first treatment provides an energy high enough for breaking bonds in the dielectric material; and performing a steam anneal on the dielectric material.
US08546241B2	Semiconductor device with stress trench isolation and method for forming the same A semiconductor device with stress trench isolation and a method for forming the same are provided. The method includes: providing a silicon substrate; forming first trenches and second trenches on the silicon substrate, wherein an extension direction of the first trenches is perpendicular to that of the second trenches; forming a first dielectric layer in the first trenches and forming a second dielectric layer in the second trenches; and forming a gate stack on a portion of the silicon substrate surrounded by the first trenches and the second trenches, wherein a channel length direction under the gate stack is parallel to the extension direction of the first trenches, indices of crystal plane of the silicon substrate are {100}, and the extension direction of the first trenches is along the crystal orientation <110>. The embodiments of the present invention can improve response speed and performance of the devices.
US08546240B2	Methods of manufacturing integrated semiconductor devices with single crystalline beam Bulk acoustic wave filters and/or bulk acoustic resonators integrated with CMOS devices, methods of manufacture and design structure are provided. The method includes forming a single crystalline beam from a silicon layer on an insulator. The method includes providing a coating of insulator material over the single crystalline beam. The method further includes forming a via through the insulator material. The method further includes providing a sacrificial material in the via and over the insulator material. The method further includes providing a lid on the sacrificial material. The method further includes providing further sacrificial material in a trench of a lower wafer. The method further includes bonding the lower wafer to the insulator, under the single crystalline beam. The method further includes venting the sacrificial material and the further sacrificial material to form an upper cavity above the single crystalline beam and a lower cavity, below the single crystalline beam.
US08546238B2	Method for transferring at least one micro-technological layer A method for transferring a micro-technological layer includes preparing a substrate having a porous layer buried beneath a useful surface, forming an embrittled zone between it and the surface, bonding the substrate to a supporting substrate, causing detachment at the porous layer by mechanical stress to obtain a first substrate remnant, and a bare surfaced detached layer joined to the supporting substrate, performing technological steps on the bared surface of the detached layer, bonding the detached layer, by the surface to which the technological steps had been applied, to a second supporting substrate, causing detachment, at the embrittled zone, by heat treatment to obtain a detached layer remnant joined to the second supporting substrate, and the detached layer remnant joined to the first supporting substrate.
US08546231B2	Memory arrays and methods of forming memory cells Some embodiments include methods of forming memory cells. A stack includes ovonic material over an electrically conductive region. The stack is patterned into rails that extend along a first direction. The rails are patterned into pillars. Electrically conductive lines are formed over the ovonic material. The electrically conductive lines extend along a second direction that intersects the first direction. The electrically conductive lines interconnect the pillars along the second direction. Some embodiments include a memory array having first electrically conductive lines extending along a first direction. The lines contain n-type doped regions of semiconductor material. Pillars are over the first conductive lines and contain mesas of the n-type doped regions together with p-type doped regions and ovonic material. Second electrically conductive lines are over the ovonic material and extend along a second direction that intersects the first direction. The second electrically conductive lines interconnect the pillars along the second direction.
US08546229B2	Methods for fabricating bipolar transistors with improved gain Insufficient gain in bipolar transistors (20) is improved by providing an alloyed (e.g., silicided) emitter contact (452) smaller than the overall emitter (42) area. The improved emitter (42) has a first emitter (FE) portion (42-1) of a first dopant concentration CFE, and a second emitter (SE) portion (42-2) of a second dopant concentration CSE. Preferably CSE≧CFE. The SE portion (42-2) desirably comprises multiple sub-regions (45i, 45j, 45k) mixed with multiple sub-regions (47m, 47n, 47p) of the FE portion (42-1). A semiconductor-metal alloy or compound (e.g., a silicide) is desirably used for Ohmic contact (452) to the SE portion (42-2) but substantially not to the FE portion (42-1). Including the FE portion (42-1) electrically coupled to the SE portion (42-2) but not substantially contacting the emitter contact (452) on the SE portion (42-2) provides gain increases of as much as ˜278.
US08546225B2	Method for manufacturing semiconductor device An embodiment of the disclosed invention is a method for manufacturing a semiconductor device, which includes the steps of forming a first insulating film; forming a source electrode, a drain electrode, and an oxide semiconductor film electrically connected to the source electrode and the drain electrode, over the first insulating film; performing heat treatment on the oxide semiconductor film to remove a hydrogen atom in the oxide semiconductor film; forming a second insulating film over the oxide semiconductor film; performing oxygen doping treatment on the second insulating film to supply an oxygen atom to the second insulating film; and forming a gate electrode in a region overlapping with the oxide semiconductor film, over the second insulating film.
US08546224B2	Method for manufacturing twin bit structure cell with aluminum oxide layer A method for manufacturing a twin bit cell structure with an aluminum oxide material includes forming a gate dielectric layer overlying a semiconductor substrate and a polysilicon gate structure overlying the gate dielectric layer. An undercut region is formed in each side of the gate dielectric layer underneath the polysilicon gate structure. Thereafter, an oxidation process is performed to form a first silicon oxide layer on a peripheral surface of the polysilicon gate structure and a second silicon oxide layer on an exposed surface of the semiconductor substrate. Then, an aluminum oxide material is deposited over the first and second silicon oxide layers including the undercut region and the gate dielectric layer. The aluminum oxide material is selectively etched to form an insert region in a portion of the undercut region. A sidewall spacer is formed to isolate and protect the exposed aluminum oxide material and the polysilicon gate structure.
US08546223B2	Semiconductor device and manufacturing method of the same The characteristics of a semiconductor device including a trench-gate power MISFET are improved. The semiconductor device includes a substrate having an active region where the power MISFET is provided and an outer circumferential region which is located circumferentially outside the active region and where a breakdown resistant structure is provided, a pattern formed of a conductive film provided over the substrate in the outer circumferential region with an insulating film interposed therebetween, another pattern isolated from the pattern, and a gate electrode terminal electrically coupled to the gate electrodes of the power MISFET and provided in a layer over the conductive film. The conductive film of the pattern is electrically coupled to the gate electrode terminal, while the conductive film of another pattern is electrically decoupled from the gate electrode terminal.
US08546222B1	Electrically erasable programmable non-volatile memory In an embodiment of the invention, a method of fabricating a floating-gate PMOSFET (p-type metal-oxide semiconductor field-effect transistor) is disclosed. A silicide blocking layer (e.g. oxide, nitride) is used not only to block areas from being silicided but to also form an insulator on top of a poly-silicon gate. The insulator along with a top electrode (control gate) forms a capacitor on top of the poly-silicon gate. The poly-silicon gate also serves at the bottom electrode of the capacitor. The capacitor can then be used to capacitively couple charge to the poly-silicon gate. Because the poly-silicon gate is surrounded by insulating material, the charge coupled to the poly-silicon gate may be stored for a long period of time after a programming operation.
US08546221B2	Voltage converter and systems including same A voltage converter includes an output circuit having a high side device and a low side device which can be formed on a single die (i.e. a “PowerDie”) and connected to each other through a semiconductor substrate. Both the high side device and the low side device can include lateral diffused metal oxide semiconductor (LDMOS) transistors. Because both output transistors include the same type of transistors, the two devices can be formed simultaneously, thereby reducing the number of photomasks over other voltage converter designs. The voltage converter can further include a controller circuit on a different die which can be electrically coupled to, and co-packaged with, the PowerDie.
US08546218B2	Method for fabricating semiconductor device with buried word line A method for fabricating a semiconductor device includes etching a substrate to form a plurality of bodies isolated by a first trench, forming a buried bit line gap-filling a portion of the first trench, etching the top portions of the bodies to form a plurality of pillars isolated by a plurality of second trenches extending across the first trench, forming a passivation layer gap-filling a portion of the second trenches, forming an isolation layer that divides each of the second trenches into isolation trenches over the passivation layer, and filling a portion of the isolation trenches to form a buried word line extending in a direction crossing over the buried bit line.
US08546217B2	Flash memory and method for forming the same A flash memory cell is provided. The flash memory cell includes: a substrate with a source line thereon; a word line and a word line dielectric layer on each side of the source line; an isolating dielectric layer which isolates the source line from the word line and the word line dielectric layer on each side of the source line; a gate stack on an outer side of each word line dielectric layer, including a floating gate dielectric layer, a floating gate, a control gate dielectric layer and a control gate; a first spacer, disposed on an outer sidewall of each word line dielectric layer and on each control gate; and a source region in the substrate and in contact with the source line. The space may be saved and the costs may be reduced.
US08546216B2	Nonvolatile semiconductor memory device and method of fabricating the same A nonvolatile semiconductor memory device includes a first insulating layer, charge storage layers, element isolation insulating films, and a second insulating layer formed on the charge storage layers and the element isolation insulating films and including a stacked structure of a first silicon nitride film, first silicon oxide film, intermediate insulating film and second silicon oxide film. The first silicon nitride film has a nitrogen concentration of not less than 21×1015 atoms/cm2. Each element isolation insulating film includes a high-temperature oxide film formed along lower side surfaces of the charge storage layers between the charge storage layers and a coating type insulating film. The first silicon nitride film is formed on an upper surface of the high-temperature oxide film in upper surfaces of the element isolation insulating films and not on the upper surface of the coating type insulating film.
US08546213B2	Method of manufacturing semiconductor device having high voltage ESD protective diode A high voltage ESD protective diode having high avalanche withstand capability and capable of being formed by using manufacturing steps identical with those for a high voltage transistor to be protected, the device having a structure in which a gate oxide film is formed over a substrate surface at a PN junction formed of an N type low concentration semiconductor substrate constituting a cathode region and a P type low concentration diffusion region constituting an anode region, and a gate electrode which is disposed overriding the gate oxide film and a field oxide film is connected electrically by way of a gate plug with an anode electrode, whereby an electric field at the PN junction is moderated upon avalanche breakdown to obtain a high avalanche withstand capability. Further, the withstand voltage can be adjusted by changing the length of the field oxide film.
US08546211B2	Replacement gate having work function at valence band edge Replacement gate stacks are provided, which increase the work function of the gate electrode of a p-type field effect transistor (PFET). In one embodiment, the work function metal stack includes a titanium-oxide-nitride layer located between a lower titanium nitride layer and an upper titanium nitride layer. The stack of the lower titanium nitride layer, the titanium-oxide-nitride layer, and the upper titanium nitride layer produces the unexpected result of increasing the work function of the work function metal stack significantly. In another embodiment, the work function metal stack includes an aluminum layer deposited at a temperature not greater than 420° C. The aluminum layer deposited at a temperature not greater than 420° C. produces the unexpected result of increasing the work function of the work function metal stack significantly.
US08546207B2	Method for fabricating semiconductor wafers for the integration of silicon components with HEMTs, and appropriate semiconductor layer arrangement The invention describes a method for fabricating silicon semiconductor wafers with the layer structures from III-V semiconductor layers for the integration of HEMTs based on semiconductor III-V layers with silicon components. SOI silicon semiconductor wafers are used, the active semiconductor layer of which has the III-V semiconductor layers (24) of the HEMT design (2) placed on it stretching over two mutually insulated regions (24a, 24b) of the active silicon layer. An appropriate layer arrangement is likewise disclosed.
US08546206B2	Enhancement mode III-nitride FET A III-nitride switch includes a recessed gate contact to produce a nominally off, or an enhancement mode, device. By providing a recessed gate contact, a conduction channel formed at the interface of two III-nitride materials is interrupted when the gate electrode is inactive to prevent current flow in the device. The gate electrode can be a schottky contact or an insulated metal contact. Two gate electrodes can be provided to form a bi-directional switch with nominally off characteristics. The recesses formed with the gate electrode can have sloped sides. The gate electrodes can be formed in a number of geometries in conjunction with current carrying electrodes of the device.
US08546205B2	Detecting a deposition condition Apparatus and methods for detecting evaporation conditions in an evaporator for evaporating metal onto semiconductor wafers, such as GaAs wafers, are disclosed. One such apparatus can include a crystal monitor sensor configured to detect metal vapor associated with a metal source prior to metal deposition onto a semiconductor wafer. This apparatus can also include a shutter configured to remain in a closed position when the crystal monitor sensor detects an undesired condition, so as to prevent metal deposition onto the semiconductor wafer. In some implementations, the undesired condition can be indicative of a composition of a metal source, a deposition rate of a metal source, impurities of a metal source, position of a metal source, position of an electron beam, and/or intensity of an electron beam.
US08546204B2	Method for growing conformal epi layers and structure thereof A method for forming a conformal buffer layer of uniform thickness and a resulting semiconductor structure are disclosed. The conformal buffer layer is used to protect highly-doped extension regions during formation of an epitaxial layer that is used for inducing mechanical stress on the channel region of transistors.
US08546198B2	Method of manufacturing transparent transistor with multi-layered structures A method of manufacturing a transparent transistor including a substrate, source and drain electrodes formed on the substrate, each having a multi-layered structure of a lower transparent layer, a metal layer and an upper transparent layer, a channel formed between the source and drain electrodes, and a gate electrode aligned with the channel. The lower transparent layer or the upper transparent layer is formed of a transparent semiconductor layer, which is the same as the channel.
US08546196B2	Non-volatile memory device and manufacturing method thereof According to one embodiment, a non-volatile memory device is formed as described below. First, a wiring material layer, which configures a part of a wiring of an element, is stacked above an element layer, the wiring material layer is processed in a predetermined shape, and the element layer is etched using the wiring material layer as a mask. Next, an insulation layer is embedded between etched patterns, and the insulation layer is removed using the wiring material layer as a stopper. Then, a wiring layer, which is in contact with the wiring material layer, is formed on the insulation layer from which the wiring material layer is exposed.
US08546192B2	System for clamping heat sink A system for clamping a heat sink that prevents excessive clamping force is provided. The system may include a heat sink, a semiconductor device, a printed circuit board, and a cover. The semiconductor device may be mounted onto the circuit board and attached to the cover. The heat sink may be designed to interface with the semiconductor device to transfer heat away from the semiconductor device and dissipate the heat into the environment. Accordingly, the heat sink may be clamped into a tight mechanical connection with the semiconductor device to minimize thermal resistance between the semiconductor device and the heat sink. To prevent excessive clamping force from damaging the semiconductor device, loading columns may extend between the cover and the heat sink.
US08546189B2	Semiconductor device and method of forming a wafer level package with top and bottom solder bump interconnection A semiconductor device is made by forming solder bumps over a copper carrier. Solder capture indentations are formed in the copper carrier to receive the solder bumps. A semiconductor die is mounted to the copper carrier using a die attach adhesive. The semiconductor die has contact pads formed over its active surface. An encapsulant is deposited over the copper carrier, solder bumps, and semiconductor die. A portion of the encapsulant is removed to expose the solder bumps and contact pads. A conductive layer is formed over the encapsulant to connect the solder bumps and contact pads. The conductive layer operates as a redistribution layer to route electrical signals from the solder bumps to the contact pads. The copper carrier is removed. An insulating layer is formed over the conductive layer and encapsulant. A plurality of semiconductor devices can be stacked and electrically connected through the solder bumps.
US08546188B2	Bow-balanced 3D chip stacking A first set of semiconductor substrates includes semiconductor chips having bonding pads arranged in a primary pattern. A second set of semiconductor substrates includes semiconductor chips having bonding pads arranged in a mirror-image pattern. A first semiconductor substrate from the first set is bonded to a second semiconductor substrate from the second set such that each bonding pads is bonded to a mirror-image bonding pad. Additional substrates are bonded sequentially such that the bonded structure includes an even number of semiconductor substrates of which one half have bonding pads of the primary pattern and are bonded to the side of the first semiconductor substrate, while the other half have bonding pads of the mirror-image pattern and are bonded to the side of the second semiconductor substrate. The mirror-image patterns of the bonding pads enable maximal cancellation of wafer bow.
US08546187B2	Electronic part and method of manufacturing the same A method of manufacturing a multi-chip module includes: securing a plurality of chips on a surface of a flat-shaped member through a solder bump; connecting the plurality of chips with each other by a bonding wire, at surfaces, opposite to the flat-shaped member side, of the plurality of chips; and electrically connecting the plurality of chips with a board, at the surfaces, opposite to the flat-shaped member side, of the plurality of chips.
US08546183B2	Method for fabricating heat dissipating semiconductor package A heat dissipating semiconductor package and a fabrication method thereof are provided. A semiconductor chip is mounted on a chip carrier. A heat sink is mounted on the chip, and includes an insulating core layer, a thin metallic layer formed on each of an upper surface and a lower surface of the insulating core layer and a thermal via hole formed in the insulating core layer. A molding process is performed to encapsulate the chip and the heat sink with an encapsulant to form a package unit. A singulation process is performed to peripherally cut the package unit. A part of the encapsulant above the thin metallic layer on the upper surface of the heat sink is removed, such that the thin metallic layer on the upper surface of the heat sink is exposed, and heat generated by the chip can be dissipated through the heat sink.
US08546182B2	Semiconductor device and method for manufacturing the same An object is, in a thin film transistor in which an oxide semiconductor is used as an active layer, to prevent change in composition, film quality, an interface, or the like of an oxide semiconductor region serving as an active layer, and to stabilize electrical characteristics of the thin film transistor. In a thin film transistor in which a first oxide semiconductor region is used as an active layer, a second oxide semiconductor region having lower electrical conductivity than the first oxide semiconductor region is formed between the first oxide semiconductor region and a protective insulating layer for the thin film transistor, whereby the second oxide semiconductor region serves as a protective layer for the first oxide semiconductor region; thus, change in composition or deterioration in film quality of the first oxide semiconductor region can be prevented, and electrical characteristics of the thin film transistor can be stabilized.
US08546179B2	Method of fabricating a self-aligned top-gate organic transistor A method of fabricating a self-aligned top-gate organic transistor comprises depositing a photoresist material over the dielectric material, and exposing the photoresist material to irradiation through the substrate using the source and drain electrodes as a mask. The exposure defines a region for deposition of the gate electrode.
US08546174B2	Method for manufacturing semiconductor device In a method for manufacturing a semiconductor device according to an embodiment, an epitaxial semiconductor layer is epitaxially grown on a semiconductor substrate, a photoelectric converting portion is formed on the epitaxial semiconductor layer, a wiring layer is formed on the epitaxial semiconductor layer after forming the photoelectric converting portion, a support substrate is bonded onto the wiring layer, and the semiconductor substrate is etched from an opposite surface side to a side for the bonding after the bonding. In the method for manufacturing a semiconductor device, an amorphous Si layer is formed on the opposite surface side of the epitaxial semiconductor layer after the etching and an antireflection film and a color filter are formed on the amorphous Si layer in sequence.
US08546173B2	Photoelectric conversion device and fabrication method therefor A photoelectric conversion device comprises a high-refractive-index portion at a position close to a photoelectric conversion element therein. And, the high-refractive-index portion has first and second horizontal cross-section surfaces. The first cross-section surface is at a position closer to the photoelectric conversion element rather than the second cross-section surface, and is larger than an area of the second cross-section surface, so as to guide an incident light into the photoelectric conversion element without reflection.
US08546169B1	Pressure sensor device and method of assembling same A pressure sensor device is assembled by forming cavities on a surface of a metal sheet and then forming an electrically conductive pattern having traces and bumps over the cavities. An insulating layer is formed on top of the pattern and then processed to form exposed areas and die attach areas on the surface of the metal sheet. The exposed areas are plated with a conductive metal and then electrically connected to respective ones of the bumps. A gel is dispensed on the die attach areas and sensor dies are attached to respective die attach areas. One or more additional semiconductor dies are attached to the insulating layer and bond pads of these dies are electrically connected to the exposed plated areas. A molding compound is dispensed such that it covers the sensor die and the additional dies. The metal sheet is removed to expose outer surfaces of the bumps.
US08546167B2	Gallium nitride-based compound semiconductor light-emitting element A nitride-based semiconductor light-emitting element includes an n-GaN layer 102, a p-GaN layer 107, and a GaN/InGaN multi-quantum well active layer 105, which is interposed between the n- and p-GaN layers 102 and 107. The GaN/InGaN multi-quantum well active layer 105 is an m-plane semiconductor layer, which includes an InxGa1-xN (where 0
US08546164B2	Method of manufacturing display device including thin film transistor A thin film transistor (TFT), including a substrate, a gate electrode on the substrate, an oxide semiconductor layer including a channel region, a source region, and a drain region, a gate insulating layer between the gate electrode and the oxide semiconductor layer, and source and drain electrodes in contact with the source and drain regions of the oxide semiconductor layer, respectively, wherein the oxide semiconductor layer has a GaInZnO (GIZO) bilayer structure including a lower layer and an upper layer, and the upper layer has a different indium (In) concentration than the lower layer.
US08546163B2	Group-III nitride semiconductor laser device, and method for fabricating group-III nitride semiconductor laser device Provided is a group-III nitride semiconductor laser device with a laser cavity allowing for a low threshold current, on a semipolar surface of a support base in which the c-axis of a hexagonal group-III nitride is tilted toward the m-axis. First and second fractured faces 27, 29 to form the laser cavity intersect with an m-n plane. The group-III nitride semiconductor laser device 11 has a laser waveguide extending in a direction of an intersecting line between the m-n plane and the semipolar surface 17a. In a laser structure 13, a first surface 13a is opposite to a second surface 13b. The first and second fractured faces 27, 29 extend from an edge 13c of the first surface to an edge 13d of the second surface 13b. The fractured faces are not formed by dry etching and are different from conventionally-employed cleaved facets such as c-planes, m-planes, or a-planes.
US08546160B2	Method for packaging light emitting diodes A method for packaging LEDs includes steps of: forming a substrate with a rectangular frame, a plurality of first and second electrode strips received within the frame and alternately arranged along a width direction of the frame; forming a carrier layer on each pair of the first and second electrode strips, the carrier layer defining a plurality of recesses; arranging an LED die in each recess and electrically connecting the LED die with first and second electrodes; forming an encapsulation in each recess to cover the LED die; and cutting the first and second electrode strips along the width direction of the frame to obtain a plurality of separated LED packages each including the first and second electrodes, the LED die, the encapsulation and a part of the carrier layer.
US08546158B2	Method for distributing phosphor particulates on LED chip A method for distributing phosphor particulates on an LED chip, includes steps of: providing a substrate having an LED chip mounted thereon; dispensing an adhesive on the chip, wherein the adhesive have positively charged phosphor particulates doped therein; providing an upper mold and a lower mold for producing an electric field through the adhesive and moving the upper mold to press the adhesive, wherein the phosphor particulates are driven by the electric field to move to a top face of the chip; and curing the adhesive and removing the upper mold and the lower mold.
US08546155B2	Via chains for defect localization Method form via chain and serpentine/comb test structures in kerf areas of a wafer. The via chain test structures comprise a first via chain and a second via chain in a first kerf area. The via chain test structures are formed such that geometrically shaped portions of the first via chain and geometrically shaped portions of the second via chain alternate along the length of the first kerf area. The methods perform relatively low (first) magnification testing to identify a defective geometrically shaped portion that contains a defective via structure. The methods then perform relatively high (second) magnification testing only within the defective geometrically shaped portion. The first magnification testing is performed at a lower magnification relative to the second magnification testing.
US08546150B2	Ultra-sensitive chemiluminescent substrates for enzymes and their conjugates New chemiluminescent compounds, stable in aqueous buffers, for use in biological assaying include acridane-based compounds and 1,2-dioxetanes. Among the new acridane-based compounds are water-soluble acridanes, enhancer coupled acridanes, bis and tris-acridanes as well as acridane-1,2-dioxetanes. Among the new 1,2-dioxetanes are electron deficient group-containing dioxetanes and tethered bis-1,2-dioxetanes. The 1,2-dioxetanes are useful as substrates for various enzymes. The acridanes can be admixed with an oxidizing agent an aqueous buffer and, optionally, a stabilizer to form a substrate or reagent formulation useful for assaying, inter alia, HRP.
US08546149B2	Potency test for vaccine formulations The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.
US08546142B2	Reverse flow perfusion of three-dimensional scaffolds The invention is a reverse-flow method and system for the loading, proliferation and differentiation of cells into and throughout an implantable biocompatible three-dimensional scaffold.
US08546141B2	Method for preparation of platelet from iPS cell A method for efficiently preparing blood cells, such as mature megakaryocytes and platelets, from iPS cells is achieved in an in vitro culture system. A sac-like structure encloses hematopoietic progenitor cells, which is obtained by inoculating iPS cells onto feeder cells and then culturing the iPS cells under conditions suitable for inducing the differentiation of hematopoietic progenitor cells. Moreover, a method for producing various types of blood cells, comprises culturing hematopoietic progenitor cells enclosed in the sac-like structure under conditions suitable for inducing the differentiation of blood cells. Furthermore, a method for producing various types of blood cells, particularly megakaryocytes and platelets, is achieved without involving the sac-like structure.
US08546139B2	Protocols for making hepatocytes from embryonic stem cells This disclosure provides a newly developed strategy and particular options for differentiating pluripotent stem cells into cells of the hepatocyte lineage. Many of the protocols are based on a strategy in which the cells are first differentiated into early germ layer cells, then into hepatocyte precursors, and then into mature cells. The cells obtained have morphological features and phenotypic markers characteristic of human adult hepatocytes. They also show evidence of cytochrome p450 enzyme activity, validating their utility for commercial applications such as drug screening, or use in the manufacture of medicaments and medical devices for clinical therapy.
US08546132B1	Testing probe for testing and validation of biological kill rates in regulated medical waste autoclaves An apparatus for safely and conveniently placing and retrieving biological indicators and/or computerized data tracers from deep within loads of Regulated Medical/Infectious Waste comprises a rod with a cavity for holding the biological indicators and/or computerized data tracers. Preferably, the rod is tapered to a point on one end, has a handle on the opposite end, and has a cover to enclose the cavity. Additionally, it is preferred that the rod is fitted with a movable sealing ring of soft material for sealing the area where the rod penetrates the waste load.
US08546128B2	Fluidics system for sequential delivery of reagents The invention provides a passive fluidics circuit for directing different fluids to a common volume, such as a reaction chamber or flow cell, without intermixing or cross contamination. The direction and rate of flow through junctions, nodes and passages of the fluidics circuit are controlled by the states of upstream valves (e.g. opened or closed), differential fluid pressures at circuit inlets or upstream reservoirs, flow path resistances, and the like. Free diffusion or leakage of fluids from unselected inlets into the common outlet or other inlets at junctions or nodes is prevented by the flow of the selected inlet fluid, a portion of which sweeps by the inlets of unselected fluids and exits the fluidics circuit by waste ports, thereby creating a barrier against undesired intermixing with the outlet flow through leakage or diffusion. The invention is particularly advantageous in apparatus for performing sensitive multistep reactions, such as pH-based DNA sequencing reactions.
US08546127B2	Bacteria/RNA extraction device Apparatus and method for collection of a target material from a liquid sample comprising target species that contain the target material. The apparatus comprises a fluid flow conduit in communication with a filter medium having a pore size adapted to retain target species thereon and pass, as filtrate, lysate containing the desired target material. A lysing agent conduit communicates with the fluid flow conduit and delivers lysing agent to the filter medium to lyse the target cells thereby releasing the desired intracellular target material. The lysing agent may be recirculated through the filter medium for a sufficient time to permit sufficient quantity of lysate to circulate through the system for lysate collection and subsequent assay.
US08546126B2	Over expression of foldases and chaperones improves protein production The present teachings provide methods for increasing protein secretion, e.g., chymosin in filamentous fungi by co-expressing certain chaperone(s) and/or foldase(s). The present teachings also provide filamentous fungi containing certain chaperone(s) and/or foldase(s) and a protein of interest for increased secretion.
US08546125B2	Recombinant hosts and methods for manufacturing polyhydroxyalkanoate Known attempts using engineered bacteria to produce P(3HB-co-4HB) with carbon sources that are structurally unrelated to 4-hydroxybutyrate resulted in relatively low 4HB monomer content of 1.5 to 5 mol %. The current invention provides recombinant hosts for producing P(3HB-co-4HB) wherein the plasmid including succinate semialdehyde dehydrogenase gene (sucD gene) and 4-hydroxybutyrate dehydrogenase gene (4hbD gene) further includes pyruvate decarboxylase promoter (Ppdc). It was found that the 4HB monomer content in P(3HB-co-4HB) is significantly enhanced to be over 20 mol %, in the range of 8.8 to 23 mol %.
US08546122B2	Subtilases The present invention relates to methods for producing variants of a parent TY145 subtilase and of a parent BPN′ subtilase and to TY145 and BPN′ variants having altered properties as compared to the parent TY145/BPN′ subtilase.
US08546121B2	Variants of an alpha-amylase with improved production levels in fermentation processes Variants of Bacillus sp. no. 707 alpha amylase are provided that are produced more efficiently and thus more economically. Higher fermentation yields are achieved through introducing amino acid variations that promote solubility of the variant in a fermentation broth. Increased solubility allows more enzyme to remain in solution after expression in a host cell. This in turn increases the efficiency with which the expressed variant enzyme can be recovered from the fermentation broth.
US08546119B2	Perhydrolase variant providing improved specific activity An acetyl xylan esterase variant having perhydrolytic activity is provided for producing peroxycarboxylic acids from carboxylic acid esters and a source of peroxygen. More specifically, a Thermotoga maritima acetyl xylan esterase gene was modified using error-prone PCR and site-directed mutagenesis to create an enzyme catalyst characterized by an increase in specific activity. The variant acetyl xylan esterase may be used to produce peroxycarboxylic acids suitable for use in a variety of applications such as cleaning, disinfecting, sanitizing, bleaching, wood pulp processing, and paper pulp processing applications.
US08546111B2	Maltotriosyl transferase and use thereof The object is to provide a novel glycosyltransferase and the use thereof, the glycosyltransferase catalyzes transglucosylation of maltotriose units under conditions which can be employed for the processing of foods or the like. Provided is a maltotriosyl transferase which acts on polysaccharides and oligosaccharides having α-1,4 glucoside bonds, and has activity for transferring maltotriose units to saccharides, the maltotriosyl transferase acting on maltotetraose as substrate to give a ratio between the maltoheptaose production rate and maltotriose production rate of 9:1 to 10:0 at any substrate concentration ranging from 0.67 to 70% (w/v).
US08546106B2	Methods of increasing secretion of polypeptides having biological activity The present invention relates to methods for producing a secreted polypeptide having biological activity, comprising: (a) transforming a fungal host cell with a fusion protein construct encoding a fusion protein, which comprises: (i) a first polynucleotide encoding a signal peptide; (ii) a second polynucleotide encoding at least a catalytic domain of an endoglucanase or a portion thereof; and (iii) a third polynucleotide encoding at least a catalytic domain of a polypeptide having biological activity; wherein the signal peptide and at least the catalytic domain of the endoglucanase increases secretion of the polypeptide having biological activity compared to the absence of at least the catalytic domain of the endoglucanase; (b) cultivating the transformed fungal host cell under conditions suitable for production of the fusion protein; and (c) recovering the fusion protein, a component thereof, or a combination thereof, having biological activity, from the cultivation medium.
US08546105B2	Engineering intracellular sialylation pathways Methods for manipulating carbohydrate processing pathways in cells of interest are provided. Methods are directed at manipulating multiple pathways involved with the sialylation reaction by using recombinant DNA technology and substrate feeding approaches to enable the production of sialylated glycoproteins in cells of interest. These carbohydrate engineering efforts encompass the implementation of new carbohydrate bioassays, the examination of a selection of insect cell lines and the use of bioinformatics to identify gene sequences for critical processing enzymes. The compositions comprise cells of interest producing sialylated glycoproteins. The methods and compositions are useful for heterologous expression of glycoproteins.
US08546103B2	Method for detecting the presence or absence of pathogenic Staphylococci in a test sample, including test mixture with micro particles A presence/absence test for Staphylococcus aureus (S. aureus) involves placing a first generation test sample in a solution that will clot in the presence of S. aureus. The solution contains components that will selectively grow S. aureus and also contains clotting factors that will react with S. aureus, if S. aureus is present in the sample, to clot the solution. Examples of specimen samples that can be tested include nasal swabs and lesion swabs, among others. The test can also be modified to detect the presence or absence of methicillin resistant S. Aureus (MRSA). The addition of micro particles having a size in the range of about 0.1 micron to about 1.0 mm provides localities where the bacteria agglomerate, thereby significantly decreasing the clotting time, and providing a significantly stronger clot. The micro particles can be used in other bacteria tests to accelerate the production of an end result. Such other tests can include a vancomycin-resistant enterococcus test; a Group B Streptococcus test; a test for hemolytic E. coli; and a test for Listeria monocytogenes, to name a few. These tests are all performed in a liquid broth-type reagent mixture and do not necessarily involve clotting of the broth.
US08546096B2	Method for identifying a non-anticoagulant sulfated polysaccharide which enhances blood coagulation dependence on FXI A method of identifying a non-anticoagulant sulfated polysaccharide (NASP) which is capable of enhancing blood coagulation in dependence of FXI, the method comprising: a) combining a blood or plasma sample having activation competent FXI with a sulfated polysaccharide and measuring the clotting or thrombin generation parameters of the blood or plasma sample; b) combining a corresponding blood or plasma sample deficient In activation competent FXI with a sulfated polysaccharide and measuring the clotting or thrombin generation parameters of the blood or plasma sample and c) comparing the clotting or thrombin generation parameters of the blood or plasma samples as determined in steps (a) and (b) with each other.
US08546095B2	Methods for determination of calcineurin activity and uses in predicting therapeutic outcomes The methods of the disclosure provide fluorescence-based assays for calcineurin activity, especially in isolated T cells. The methods include the stimulation of the T cells with agents that specifically target the TCR with or without influencing co-stimulatory pathways. One TCR agonist is monoclonal antibodies specific for CD3, which more precisely distinguish the inducible activity of calcineurin than does an alternative method targeting the T cell receptor (CD3) combined with CD28 costimulation. This method more accurately distinguishes between the measured level of calcineurin activity of T cells from immunosuppressed transplant recipients and normal individuals, and thus has improved diagnostic accuracy with respect to the response of an individual to immunosuppressant therapy following an organ transplant.
US08546093B2	Detection method for methicillin resistant staphylococcus aureus The present invention relates to an antibody against a protein specifically expressed in methicillin-resistant strains of Staphylococcus aureus (MRSA), and a method and a kit for detecting MRSA. The present invention enables a fast and accurate detection of MRSA by using both a PBP2a-specific antibody for the detection of PBP2a and a Protein A-specific antibody for the detection of Protein A.
US08546088B2	Porphyrinic compounds for use in flow cytometry The present invention provides a method of detecting (e.g., by flow cytometry) a target compound, cell or particle, wherein the target is labelled with a detectable luminescent compound. The method comprises utilizing as the detectable luminescent compound a compound comprising a porphyrinic macrocycle such as a porphyrin, chlorin, bacteriochlorin, or isobacteriochlorin. In particular embodiments, the detectable luminescent compound comprises a compound of the formula A-A′-Z-B′-B, wherein: A is a targeting group or member of a specific binding pair that specifically binds the detectable luminescent compound to the target compound, cell or particle; A′ is a linker group or covalent bond; B′ is a linker group or covalent bond; B is a water-soluble group; and Z is the porphyrinic macrocycle.
US08546084B2	Device and method for identifying and determining blood groups A device for the determination and/or the detection of erythrocyte blood groups from a whole blood sample, and a process that implements this device, as well as a kit for the determination and the detection of blood groups are disclosed.
US08546077B2	Prostaglandin E2 modulation and uses thereof Methods, uses, kits and products are described for the prognosis, diagnosis, prevention and treatment of myotronic dystrophy type 1 (DM1), and more particularly for the prognosis, diagnosis, prevention and treatment of the congenital form of myotronic dystrophy type 1 (cDM1), based on changes in/modulation of prostaglandin E2 (PGE2).
US08546076B2	Mutational profile in HIV-1 GAG cleavage site correlated with phenotypic drug resistance The invention concerns novel mutations or mutational profiles of HIV-1 protease cleavage sites (CS) in the Gag region correlated with a phenotype causing alterations in sensitivity to anti-HIV drugs. The present invention also relates to the use of genotypic characterization of a target population of HIV and the subsequent association, i.e., correlation, of this information to phenotypic interpretation in order to correlate virus mutational profiles with drug resistance. The invention further relates to methods of utilizing the mutational profiles of the invention in databases, drug development, i.e., drug design, and drug modification, therapy and treatment design and clinical management.
US08546070B1	Color photographic silver halide paper and use A color photographic element has a reflective support and a blue light sensitive color record, a green light sensitive color record, and a red light sensitive color record can be used to provide color photographic prints. The element also has a non-light sensitive interlayer between the green light and red light sensitive color records. This interlayer comprises a hydrophilic colloid and an acrylic latex polymer having a glass transition temperature (Tg) of less than 0° C. The presence of this acrylic latex polymer in the interlayer reduces the formation of a cyan line defect when the color photographic print is folded or creased, such as in photobooks.
US08546069B2	Method for enhancing lithographic imaging of isolated and semi-isolated features The present invention relates to photolithography methods for enhancing lithographic imaging of isolated and semi-isolated features. A first layer of a first photoresist is formed over a substrate. A second layer of a second photoresist is formed over the first layer. The second photoresist includes a polymer containing an absorbing moiety. The second layer is exposed through a first patterned mask and developed to form a first relief image. The first relief image and the first layer are exposed through a second patterned mask. One of the first and the second patterned masks includes a dense pattern, while the other includes an isolated or a semi-isolated pattern. The first relief image and base soluble regions of the first layer are removed to form a second relief image with an isolated or a semi-isolated pattern. The second layer can also be bleachable upon exposure and bake in the present invention.
US08546067B2	Material assisted laser ablation This invention provides photoablation—based processing techniques and materials strategies for making, assembling and integrating patterns of materials for the fabrication of electronic, optical and opto-electronic devices. Processing techniques of the present invention enable high resolution and/or large area patterning and integration of porous and/or nano- or micro-structured materials comprising active or passive components of a range of electronic devices, including integrated circuits (IC), microelectronic and macroelectronic systems, microfluidic devices, biomedical devices, sensing devices and device arrays, and nano- and microelectromechanical systems.
US08546064B2	Method to produce a fuel cell flowfield with photopolymer walls A method for fabricating a flowfield for a fuel cell includes the steps of: providing a substrate; providing a plurality of radiation sources configured to generate a plurality of radiation beams; disposing a radiation-sensitive material on the substrate; placing an imaging mask between the plurality of radiation sources and the radiation-sensitive material; and exposing the radiation-sensitive material to the plurality of radiation beams through a first portion of the radiation-transparent apertures and a second portion of the radiation-transparent apertures in the imaging mask to form the plurality of truss elements and the plurality of wall elements in the radiation-sensitive material, the truss elements forming a plurality of trusses configured to support an adjacent diffusion medium layer, and the wall elements defining a fluid path along a length of the substrate.
US08546060B2	Chemically amplified positive resist composition and pattern forming process A chemically amplified positive resist composition is provided comprising a polymer PB having an amine structure bound thereto and a polymer PA comprising recurring units having an acidic side chain protected with an acid labile protective group and recurring units having an acid generating moiety on a side chain.
US08546058B2	Electrostatic latent image developing toner, electrostatic latent image developer, image forming apparatus, and apparatus for manufacturing electrostatic latent image developing toner A method for forming an electrostatic latent image developing toner including mixing in a stirring tank a resin particle dispersion with at least a colorant particle dispersion prepared by dispersing a colorant and in some cases with a release agent particle dispersion prepared by dispersing a release agent; aggregating in the stirring tank the resin particles with the pigment particles and the release agent particles to form aggregate particles; and then conducting heating in the stirring tank to fuse the aggregate particles, wherein the method further comprises during a fusion step, suppressing with an accumulation suppression unit accumulation of aggregate particles. The accumulation suppression unit is a magnetic field forming unit that forms a magnetic field either continuously or intermittently. The toner has an average sphericity of at least 0.94 but no more than 0.98 and particle characteristics as defined in the specification.
US08546053B2	Toner, and production method of the same The present invention provides a method for producing a toner, the method including: preparing a wax dispersion liquid by cooling a wax solution, in which a wax is heated and dissolved or dispersed in an organic solvent, in a container so that a standard deviation σ of a temperature distribution between a center portion of the container and an inner wall of the container is 0.5 or less and the cooling rate is 2.0° C./min or more, to precipitate wax particles in the wax solution; forming toner base precursor particles by adding an aqueous phase containing resin fine particles into an oil phase containing at least the wax dispersion liquid, a colorant and a binder resin and mixing the oil phase and the aqueous phase with each other; and preparing toner base particles by removing the solvent from the toner base precursor particles.
US08546052B2	Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus, and process for producing electrophotographic photosensitive member An electrophotographic photosensitive member having a surface layer containing a polymeric product obtained by polymerizing a specific adamantane compound, a process cartridge and an electrophotographic apparatus which have the electrophotographic photosensitive member, and a process for producing the electrophotographic photosensitive member.
US08546048B2	Forming sloped resist, via, and metal conductor structures using banded reticle structures A technique generating sloping resist profiles based on an exposure process uses a reticle having structures surrounded with first and second contrasting interleaved bands below the resolution limit of the stepper used to expose the resist. Exemplary embodiments include a reticle having interleaved, non-overlapping transparent and opaque bands surrounding a transparent feature with an innermost one of the opaque bands bordering the structure, such as a via opening or a metal conductors pattern, resulting in the patterned photoresist having sloped or tapered sides with consistent reproducibility. The slope in the photoresist is then transferred to the underlying layer during an etch using the tapered photoresist as a mask. Alternatively, the sloped resist can have a negative slope angle for patterning metal conductors using a metal lift-off technique.
US08546046B2	Method for fabricating bi-polar plate of fuel cell and bi-polar plate of fuel cell A method for fabricating a bi-polar plate of a fuel cell and the bi-polar plate thereof are presented. A graphite film is formed first. Next, a polymeric material added with electrically conductive powder is coated on a surface of a metal substrate. The graphite film is disposed on the polymeric material and the polymeric material is hardened to form an adhesive layer, such that the graphite film is attached on the surface of the metal substrate.
US08546045B2	Gasketed subassembly for use in fuel cells including replicated structures An electrochemical device subassembly is provided that includes a membrane electrode assembly and a gasket. The membrane electrode assembly includes an electrolyte membrane having a first major surface, a second major surface opposite the first major surface, and a peripheral edge. The gasket is disposed adjacent the first major surface of the electrolyte membrane at the peripheral edge, and has a plurality of replicated structures that extend greater than about 250 micrometers from a surface of the gasket.
US08546038B2	Fuel cell separator having reactant gas channels with different cross sections and fuel cell comprising the same A fuel cell separator of the present invention is a plate-shaped fuel cell separator including a reaction gas supply manifold hole (21), a reactant gas discharge manifold hole (22), a groove-shaped first reactant gas channel (131), and one or more groove-shaped second reaction gas channels (132, 133), wherein the first reactant gas channel (131) includes a first portion (41) and a second portion (51) located upstream of the first portion (41), and a cross-sectional area of a continuous portion extending from the upstream end of the first reactant gas channel (131) and/or a cross-sectional area of at least a portion of the first reactant gas channel (131) which lies downstream of the first portion (41) is/are smaller than cross-sectional areas of the second reactant gas channels (132, 133).
US08546027B2	System and method for directed self-assembly technique for the creation of carbon nanotube sensors and bio-fuel cells on single plane Improved nanotube devices and systems/methods for fabrication thereof are provided. The present disclosure provides systems/methods for depositing controlled numbers of nanotubes with specific properties at predefined locations for the fabrication of nanotube devices. The nanotube devices may be utilized in a range of applications. A bio-fuel cell system that does not require a proton exchange membrane separator and does not need a mediator to transfer charge is provided. This exemplary bio-fuel cell uses enzyme functionalized SWNTs for the anode/cathode. The absence of a membrane in the bio-fuel cell configuration opens up the possibility of other configurations that would otherwise be unfeasible. This includes a bio-fuel cell where the anode/cathode are on the same substrate. Since the electrodes can share the same substrate, the configuration may be integrated with a circuit device on the same substrate. An IC and its power source may be fabricated on the same silicon wafer.
US08546026B2	Gas-liquid separator, hydrogen generating apparatus, and fuel cell generation system having the same Disclosed are a gas-liquid separator, a hydrogen generating apparatus, and a fuel cell generation system, having the same. The gas-liquid separator can include an inflow path, into which a fluid material having a liquid and a gas flows; a centrifugal path, connected to the inflow path to receive the fluid material and formed spirally such that the fluid material is separated into the liquid and the gas by difference in centrifugal forces, an outer side of the centrifugal path having stronger affinity for the liquid than an inner side of the centrifugal path; and an outflow path, connected to the centrifugal path and discharging the liquid and the gas, which have been separated in the centrifugal path. With the present invention, it is possible to efficiently separate gas such as hydrogen and liquid such as a electrolyte solution without complex devices.
US08546024B2	Non-aqueous electrolyte lithium secondary battery A lithium secondary battery has an anode, a cathode, a separator between the anode and the cathode and a non-aqueous electrolyte. The non-aqueous electrolyte includes a lithium salt; and a non-linear carbonate-based mixed organic solvent in which (a) a cyclic carbonate compound, and (b) a propionate-based compound are mixed at a volume ratio (a:b) in the range from about 10:90 to about 70:30, and optionally (c) a vinylene carbonate; and an inhibitor against a reaction between the anode and the propionate-based ester compound. The cathode has a current density in the range from about 3.5 to about 5.5 mA/cm2 and a porosity in the range from about 18 to about 35%. This battery may be manufactured as a high-loading lithium secondary battery.
US08546013B2	Cylindrical battery and method of manufacturing the same A cylindrical battery is formed by sealing an electrode wound body in a cylindrical case and having an outer terminal member mounted to one end of the battery so as to axially penetrate through a gasket having a cylindrical portion and collar portions. A neck is formed at the inner surface of the case. A flange having an outer diameter greater than the inner diameter of the neck is formed on the outer terminal member. To mount the outer terminal member to the case, the gasket is mounted to the flange, liquid is charged from a through-hole with the flange held in a temporarily sealed state in which the flange is pressed into the case until being in contact with the neck, and an end portion of the case is bent to the inner surface side thereof to press the collar portion to the flange to complete sealing.
US08546009B2	Method and apparatus for thermal energy transfer A thermal energy transfer element includes a thermally conductive core and, in some embodiments, a sleeve. The core has first and second portions. The first portion is for placement in direct contact with and to be surrounded by an electrolyte. The sleeve surrounds at least the first portion of the transfer element. The first portion conducts thermal energy between the electrolyte and the second portion.
US08546008B2	Electronic device facilitating loading or unloading of battery through latching module Provided is an electronic device, comprising: a casing, comprising an accommodation space that a battery is detachably assembled therein. The battery comprises a hook extending towards the casing, a first and a second urging surfaces that a step connected there between; and a latching module, disposed in the casing and moving back and forth between a first and a second positions. When the latching module moves from the first position towards the second position, the hook, the first urging surface, the step, and the second urging surface are sequentially located in a moving path of a urging portion of the latching module. When the latching module is located at the first position, the urging portion is buckled to the hook. When the latching module is located at the second position, the urging portion is limited by the step and rests on the second urging surface.
US08546002B2	Yeast biofilm based fuel cell A yeast biofilm microbial fuel cell has anode and cathode chambers, each containing an electrolyte medium, separated by a proton conducting membrane. A baker's yeast biofilm is induced to form on the anode under electrical poising. A method of making the MFC includes adding baker's yeast and yeast nutrient fuel source to the anode solution, connecting a resistor across the anode and cathode to enable current flow through the resistor for a selected time for poising the anode and formation of the anodic yeast biofilm, replacing the anode solution with a fresh quantity of yeast-free solution, adding fuel source to the solution, and continuing to run the MFC for a selected time under resistance. The steps of replacing the anode solution, adding fuel source and running the cell under load are repeated until the baker's yeast has formed a suitable anodic biofilm.
US08546000B2	Perpendicular magnetic disc A perpendicular magnetic disk that includes, a base 110, a granular magnetic layer 160, and a auxiliary recording layer 180 disposed as an upper layer of the granular magnetic layer 160. The granular magnetic layer 160 has a granular structure in which a grain boundary portion is formed by segregation of a non-magnetic substance containing an oxide as a main component around magnetic particles containing a CoCrPt alloy grown in a columnar shape as a main component. The auxiliary recording layer 180 contains a CoCrPtRu alloy as a main component and has a film thickness of 1.5 nm to 4.0 nm. With this structure, the auxiliary recording layer can be thinned while maintaining the function thereof to improve SNR.
US08545994B2	Electrodeposited metallic materials comprising cobalt An article includes an electrodeposited metallic material including Co with a minimum content of 75% by weight. The metallic material has a microstructure which is fine-grained with an average grain size between 2 and 5,000 nm and/or an amorphous microstructure. The metallic material forms at least part of an exposed surface of the article. The metallic material has an inherent contact angle for water of less than 90 degrees at room temperature when measured on a smooth exposed surface portion of the metallic material which has a maximum surface roughness Ra of 0.25 microns. The metallic material has an exposed patterned surface portion having surface structures having a height of between at least 5 microns to about 100 microns incorporated therein to increase the contact angle for water at room temperature of the exposed patterned surface portion to over 100 degrees.
US08545992B2	Aluminum article An aluminum article includes a substrate made of aluminum or aluminum alloy, a Ni—Cu—P alloy layer formed on the substrate, and a Ni—P alloy layer directly formed on the Ni—Cu—P alloy layer. The Ni—Cu—P alloy layer consists substantially of nickel, copper, and phosphorus and has a crystalline state. The Ni—P alloy layer consists substantially of nickel and phosphorus and has an amorphous structure. A method for making the aluminum article is also provided.
US08545991B2	Low thermal conductivity misfit layer compounds with layer to layer disorder Compositions comprise an alternating plurality of ordered layers of a first composition MX and a second composition TX2, wherein M is one of Sn, Pb, Sb, Bi, or a rare earth metal, X is S or Se and T is Ti, V, Cr, Nb, or Ta. In some examples, the alternating plurality of ordered layers conforms to a substrate. In typical examples, each of the ordered layers of the first composition has a common thickness and/or each of the ordered layers of the first material has a common composition. In some examples, each of the ordered layers of the second composition has a common thickness and/or a common composition.
US08545990B2	Coated article and method for manufacturing A coated article includes a substrate, a first magnesium-tin alloy layer, a tin layer, a second magnesium-tin alloy layer, a magnesium layer and a magnesium-nitrogen layer. The substrate is made of magnesium or a magnesium alloy. The substrate made of magnesium or magnesium alloy. The first magnesium-tin alloy layer formed on the substrate. The tin layer formed on the first magnesium-tin alloy layer. The second magnesium-tin alloy layer formed on the tin layer. The magnesium layer formed on the second magnesium-tin alloy layer. The magnesium-nitrogen layer formed on the magnesium layer.
US08545987B2	Thermal interface material with thin transfer film or metallization According to various aspects, exemplary embodiments are provided of thermal interface material assemblies. In one exemplary embodiment, a thermal interface material assembly generally includes a thermal interface material having a first side and a second side and a metallization layer having a layer thickness of about 0.0005 inches or less. The metallization layer is disposed along at least a portion of the first side of the thermal interface material.
US08545983B2	Super-low fouling sulfobetaine materials and related methods Super-low fouling sulfobetaine and carboxybetaine materials, super-low fouling surfaces and methods of making the surfaces coated with sulfobetaine and carboxybetaine materials, and devices having the super-low fouling surfaces.
US08545978B2	Composite film To provide a composite film having low-temperature flexibility. The composite film including an acrylic polymer and a urethane polymer, in which the acrylic polymer includes an acryl component containing at least an acrylic acid-based monomer and a monofunctional acrylic monomer whose homopolymer has a glass transition temperature (Tg) of 273 K or more; the content of said acrylic acid-based monomer in said composite film is from 0.5 to 15 wt %; the glass transition temperature (Tg ac) of the acrylic polymer is 273 K or more; the glass transition temperature (Tg ur) of the urethane polymer is 273 K or less; and the glass transition temperature (Tg) of the composite film is 269 K or less.
US08545977B2	Polymer concrete electrical insulation Polymer concrete electrical insulation including a hardened epoxy resin composition filled with an electrically non-conductive inorganic filler compositions. The polymer concrete electrical insulation system optionally may contain additives. The epoxy resin composition is based on a cycloaliphatic epoxy resin. The inorganic filler composition can be present within the range of about 76% by weight to about 86% by weight, calculated to the total weight of the polymer concrete electrical insulation system. The inorganic filler composition includes a uniform mixture of (i) an inorganic filler with an average grain size within the range of 1 micron (μm) to 100 micron (μm) [component c(i)], and (ii) an inorganic filler with an average grain size within the range of 0.1 mm (100 micron) to 2 mm [component c(ii)]. The inorganic filler with an average grain size within the range of 1 micron (μm) to 100 micron (μm) [component c(i)] can be present in an amount within the range of 22% to 42%, calculated to the total weight of the polymer concrete electrical insulation system; and (e) the inorganic filler with an average grain size within the range of 0.1 mm to 2 mm [component c(ii)] is present within the range of 41% to 61% by weight, calculated to the total weight of the polymer concrete electrical insulation; and method of producing said electrical insulation.
US08545972B2	Controlled vapor deposition of multilayered coatings adhered by an oxide layer An improved vapor-phase deposition method and apparatus for the application of multilayered films/coatings on substrates is described. The method is used to deposit multilayered coatings where the thickness of an oxide-based layer in direct contact with a substrate is controlled as a function of the chemical composition of the substrate, whereby a subsequently deposited layer bonds better to the oxide-based layer. The improved method is used to deposit multilayered coatings where an oxide-based layer is deposited directly over a substrate and an organic-based layer is directly deposited over the oxide-based layer. Typically, a series of alternating layers of oxide-based layer and organic-based layer are applied.
US08545969B2	Pattern-formed substrate, pattern-forming method, and die A pattern-formed substrate is provided. The pattern-formed substrate includes a substrate base, an organic thin film and an inorganic resist film stacked on the substrate base in this order, and patterns having predetermined aspect ratios formed on the organic thin film and the inorganic resist film, respectively. The pattern of the organic thin film is formed by selective etching using the pattern of the inorganic resist film as a mask.
US08545967B2	Multi coated metal substrate and method for the production thereof A metal sheet, inclusive of a metal strip, having a front side and a back side, both the front side and the back side comprising a first coating having an average thickness in the range from 0.5 to 10 μm, wherein the first coating of the front side contains particles, which release divalent or multivalent metal ions upon the action of an acid, in such an amount that a self-depositing coating agent forms, upon contact with the front side, a second coating thereon, whereas this is not the case for the first coating of the back side. The first coating of the front side can be overcoated with a self-depositing coating agent. Cut edges that do not have a first coating can be covered with the self-depositing coating agent. Correspondingly coated metal sheets, as well as a method for the manufacture thereof, are furthermore within the scope of the invention.
US08545965B2	Method of manufacturing of lightweight structural trim part and lightweight structural trim part produced A method for manufacturing a lightweight structural trim part is comprising the following steps: (A) inserting a plurality of layers into a molding tool comprising a first molding half (6) and a second molding half (7). The second molding half (7) comprises a plurality of cup-like indentation (8). The plurality of layers at least comprises a first air permeable skin layer (1) facing the first molding half (6), a second air tight skin layer (3,4) facing the second molding half (7), and a film layer (2) between the two skin layers. (B) Closing the molding tool and discharging gas from one side in order to press the first skin layer against the first molding half. (C) Shaping and consolidating the first porous skin layer. (D) Charging with pressurized air the first space in order to press the second skin layer against the second molding half. (E) Shaping and consolidating the second skin layer. (F) Meanwhile bonding the first and second skin layer to each other in the area between the cup-like indentations, in order to form an acoustic body comprising a plurality of cup-like cavities.
US08545962B2	Nano-fiber arrayed surfaces Surfaces are provided comprising an array of partially embedded nano-fibers. Two such surfaces may contact each other such that the respective nano-fibers contact at orthogonal angles, resulting in ultra-low friction and ultra-low adhesion contact. Such configurations are useful in several NEMS or MEMS applications, as well as macro-sized applications. Alternatively, the surfaces may contact each other such that the respective nano-fibers are parallel. These configurations are useful in micro-stage or high-order three-dimensional self assembly applications.
US08545960B2	Articles comprising protective sheets and related methods Methods of the invention include those for applying protective sheets to articles. According to these methods and resulting articles, a protective sheet is applied to at least a portion of an exterior surface where protection is desired on an article. At least one portion of at least one exterior surface of the article to be protected can be integrally formed in the presence of the protective sheet. Improved bonding of the protective sheet to the article and improved processing efficiency are advantageously achieved according to the invention.
US08545958B2	Reinforced block made from composite material and method for reinforcing a composite block A block including at least one glass ply at least partially covering an outer surface of a core made from composite material. A method for reinforcing a block made from a composite material, including a glass ply placed in a mold, such as to cover the base of the mold; the block is positioned in the mold; the edges of the glass ply are folded such that the glass ply is molded to the outer edge of the block; the mold is closed with a cover; the block housed inside the mold is cured in an oven such as to polymerize the glass ply; and the glass-ply-covered block is recovered.
US08545946B2	Liquid crystal alignment solution A liquid crystal alignment solution is provided, including at least one polymer selected from the group consisting of a polyamide acid-polyamide acid polymer represented by formula (A), a polyimide-polyamide acid polymer represented by formula (B) and a polyimide-polyimide polymer represented by formula (C), as defined in the contexts.
US08545945B2	Micropattern generation with pulsed laser diffraction Methods and devices for preparing microscale polymer relief structures from a thin polymer layer on an absorbing substrate are described. The described methods are ultrafast (about 8 nanoseconds) and allow formation of patterned microstructures having complex morphologies and narrow line widths that are an order of magnitude smaller than the masks used in the methods.
US08545941B2	Method of drying coating liquid agent and apparatus therefor In an oven used for printing machine and the like, drying is rendered possible to be conducted without decreasing traveling speed (120 m/min or more) by a short and compact drying zone for a coating liquid agent which is made aqueous as well as oily coating liquid agent. A plurality of hot air blow-off nozzles 222 are provided in the drying portion 220 of the first printing unit 200. Heating guide rolls 223a are provided at the former portion, and cooling guide rolls 223b are provided at the latter portion, so that they meet the hot air blow-off nozzles 222. Liquid delivery pipes 224a for injecting hot water are connected to the heating guide rolls 223a, and liquid delivery pipes 224b for injecting cooling water are connected to the cooling guide rolls 223b. Introduced raw web 1 is heated to the boiling point of solvent or higher than that by the heating guide rolls 223a.
US08545939B2	Method and device for the infiltration of a structure of a porous material by chemical vapour deposition A method and a device for infiltration of a structure made of a porous material by chemical vapor deposition. According to the method, a first face of the porous material structure is exposed to a gaseous flow, and the second face is maintained at least partially free from any contact.
US08545936B2	Methods for forming carbon nanotubes Methods of forming a roughened metal surface on a substrate for nucleating carbon nanotube growth, and subsequently growing carbon nanotubes are provided. In preferred embodiments roughened surfaces are formed by selectively depositing metal or metal oxide on a substrate surface to form discrete, three-dimensional islands. Selective deposition may be obtained, for example, by modifying process conditions to cause metal agglomeration or by treating the substrate surface to provide a limited number of discontinuous reactive sites. The roughened metal surface may then be used as nucleation points for initiating carbon nanotube growth. The carbon nanotubes are grown in the same process chamber (in-situ) as the formation of the three dimensional metal islands without exposing the substrate to air.
US08545927B2	Lactoferrin-based biomaterials for tissue regeneration and drug delivery The invention provides biomatrix compositions comprising cross-linked lactoferrin, either alone or in combination with other organic or inorganic components. Also provided are methods of making and using the biomatrix compositions. As described herein, cross-linked lactoferrin biomatrix retains the bioactivities of the lactoferrin molecule. The biomatrix composition can act as a matrix for cell adhesion and growth and is particularly useful in musculoskeletal tissue regeneration. The biomatrix compositions can be pre-formed or injectable and can act as a cell, drug or protein delivery vehicle.
US08545926B2	Method of forming insulated conductive element having substantially continuously coated sections separated by uncoated gaps Coating an elongate, uncoated conductive element with a barrier layer to form an insulated conductive element. The insulated conductive element comprises substantially continuously coated elongate sections separated by uncoated gaps which are substantially small relative to the lengths of the coated sections.
US08545925B2	Candy composition with excellent sweetness and candy using the same It is an object of the invention is to provide a candy composition in which a sugar alcohol is used as a main raw material and which is comparable in intensity of sweetness and quality of sweetness to sugar as well as a candy manufactured using the same.The above object can be accomplished by providing a deliciously sweet candy composition which comprises sugar alcohol as a main raw material and comprises high sweetness intensity sweetener (E), flavoring components (A) maltol and (B) furaneol as essential components, each in an effective amount, and an effective amount of at least one component selected from among flavoring components (C) cyclotene and (D) menthyl acetate.
US08545923B2	Method of cutting ham and product thereof A ham product and method for production thereof described herein separate bone-in hams into smaller pieces. Accordingly, pieces of bone-in ham, even those spirally-sliced, will be available to consumers in smaller portions. Unlike conventional methods, however, the ham product provides three or four pieces of essentially equal size that each have a nearly equal meat-to-bone ratio. Furthermore, when a spiral cut ham is separated into pieces, each piece includes a portion of the femur and retains attachment of the slices to the femur so that the slices stay intact during handling and packaging and so that the pieces retain the natural shape and easy handling desired by consumers.
US08545922B1	Method for reducing microbial contamination for poultry A method of reducing pathogenic bacteria in the neck of poultry is provided. The method includes opening up a neck of a poultry (20) and rupturing cervical air sacs (12). The exposed, ruptured cervical air sacs are treated with an antibacterial agent, thereby reducing pathogenic bacteria.
US08545921B2	Chocolate composition The invention relates to chocolate compositions where the fat phase comprises at least cocoa butter and optionally milk fat and/or a cocoa butter equivalent and the chocolate can be liquefied and re-solidified without bloom and without a pre-crystallization step.
US08545918B2	Method of cutting ham and product thereof A ham product and method for production thereof described herein separate bone-in hams into smaller pieces. Accordingly, pieces of bone-in ham, even those spirally-sliced, will be available to consumers in smaller portions. Unlike conventional methods, however, the ham product provides three or four pieces of essentially equal size that each have a nearly equal meat-to-bone ratio. Furthermore, when a spiral cut ham is separated into pieces, each piece includes a portion of the femur and retains attachment of the slices to the femur so that the slices stay intact during handling and packaging and so that the pieces retain the natural shape and easy handling desired by consumers.
US08545917B2	Preparation of an edible product from dough The present invention is directed to mold control and extended shelf life methods and compositions for preparing edible dough-based products, such as, for example, breads, by treating the surface of the dough used to prepare the edible product with at least one preservative and at least one pH adjusting agent prior to or during baking. The present invention is also directed to methods and compositions for preparing edible dough-based products, such as, for example, breads, by treating the surface of the dough used to prepare the edible product with a at least one pH adjusting agent prior to or during baking. The present invention is further directed to improved pan oil compositions for preparing edible dough based products which comprise at least one preservative in an amount effective to inhibit mold growth on the surface of the bread prepared from the dough and at least one pH adjusting agent in an amount effective to improve the activity of the at least one preservative and/or inhibit microbial growth on the surface of the bread prepared from the dough.
US08545910B2	Method of processing green coffee beans by using surface-treated coffee cherries There is provided a method for processing green coffee beans capable of imparting new aromas and flavors to a coffee beverage using a simple operation, without incurring an increase in raw material costs.The method for processing green coffee beans includes a fermentation step of bringing nutritive substances included in coffee cherries and microorganisms into contact with one another and causing fermentation, and a collection step of separating and collecting green coffee beans from the coffee cherries that have undergone the fermentation step, wherein in the fermentation step, at least part of the pulp of the coffee cherries is exposed, and the microorganisms are caused to come into direct contact therewith.
US08545909B2	Method of producing non-bovine chymosin and use hereof A method of recombinantly producing a non-bovine pre-prochymosin, prochymosin or chymosin derived from ruminant species including deer species, buffalo species, antelope species, giraffe species, ovine species and caprine species; Camelidae species such as Camelus dromedarius; porcine species; or Equidae species. The recombinant enzymes are used in milk coagulating compositions in cheese manufacturing based on cow's milk and milk from any animal species which are used in cheese manufacturing including camel's milk.
US08545906B2	Pest-impervious packaging material and pest-control composition A composition-of-matter comprising a substance usable in producing packaging material and at least one compound selected from the group consisting of ar-turmerone, a sesquiterpene alcohol and a turmeric oleoresin solid residue.
US08545905B2	Whitening cosmetic composition containing green tea extract The present invention relates to a whitening cosmetic composition containing a green tea extract and, more particularly, to a whitening cosmetic composition containing a green tea extract that is prepared from green tea leaves by hot water extraction and liquid culture with Aspergillus oryzae to provide a high inhibitory effect on tyrosinase.
US08545901B2	Topical composition comprising extracts of A. indica and M. charantia or S. indicum The invention relates to a topical composition and a method for reducing or preventing occurrence of acne on the skin. It is an object of the present invention to provide for a combination of herbal extracts that interact synergistically to provide a cosmetic composition for prevention, reduction or treatment of acne. The present invention provides for a topical composition comprising (i) an extract of a first active which is Azhadirachta indica; and (ii) an extract of a second active selected from Momordica charantia or Sesamum indicum.
US08545900B2	Method of obtaining total fixed lipids from seeds of the sapotaceae family, for the preparation of cosmetics and dermatological pharmaceutical compositions Procedure for the obtaining a concentrate of the total fixed lipids of the kernels of the family Sapotaceae, genus Calocarpum, Chrysophyllum and Lucuma. The kernels (seeds removed of the endocarp), are squeezed by means of mechanical techniques that use pressure and heat, without using extractive liquids, getting a concentrate of lipidic juices (virgin) in a dry way and with their characteristic aroma. This concentrate of total fixed lipids can be fractioned in its main constituents by means of a process that consist of the emulsification of the lipids, followed by centrifugation or sedimentation, giving place to the stratification of the main constituents and their consequent separations. The main constituent consist of oils, of phospholipids and of residues glucosidic triterpenes plus of sterols fractions. These fraction or as a whole concentrate are used to prepare cosmetics and pharmaceutical compositions of topical application, to act in the skin like anti-seborrheic, healing, promoter of delicate defoliation and as invigorated epithelia regeneration agents, as cutaneous anti-wrinkle agent and as adjuvant in the development of the hair.
US08545893B2	Keratin biomaterials for treatment of ischemia Provided herein are keratin compositions useful for treating ischemia and/or reperfusion injury, such as that associated with myocardial infarct, ischemic stroke, brain trauma such as traumatic brain injury, hypothermia, chronic wounds, and burns.
US08545887B2	Modified release dosage forms A dosage form comprises: (a) at least one active ingredient: (b) a core having a first surface portion upon which resides a first coating and a second surface portion which is substantially free of the first coating; and (c) a shell which resides upon at least a portion of the second surface portion, wherein the shell comprises a different material from the first coating. In another embodiment, the dosage form comprises: (a) at least one active ingredient; (b) a core comprising a center portion having an exterior surface and an annular portion having an exterior surface and an interior surface, wherein the annular portion interior surface is in contact with at least a portion of the center portion exterior surface, and a coating resides on at least a portion of the annular portion exterior surface; and (c) a shell which resides upon at least a portion of the exterior surface of the center portion, wherein the shell comprises a different material than the impermeable coating. In another embodiment, the dosage form comprises: (a) at least one active ingredient; (b) a core having an outer surface and a cavity which extends at least partially through the core such that the core outer surface has at least a first opening therein; (c) a first coating which resides on at least a portion of the core outer surface, wherein the first shell portion comprises a different material from the first coating; and (d) a first shell portion which is adjacent to the first opening and covers at least the first opening.
US08545886B2	Extended release tablet formulations of flibanserin and method for manufacturing the same The invention is directed to a Pharmaceutical extended release system, particularly for oral administration, of a pH-dependent water-soluble active substance, comprising or essentially consisting of a) flibanserin or a pharmaceutically acceptable derivative thereof as active substance; b) one or more pharmaceutically acceptable pH-dependent polymers; c) one or more pharmaceutically acceptable pH-independent polymers; d) one or more pharmaceutically acceptable acids; and e) optionally one or more additives. The present invention provides a release profile of flibanserin which is independent on the pH in the gastrointestinal tract when administered orally resulting in a significantly improved bioavailability.
US08545885B2	Stable laquinimod preparations The subject invention provides a pharmaceutical composition comprising N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide or the salt thereof; a pharmaceutically acceptable carrier; and not more than 0.5% w/w relative to N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide of 2-Chloro-6-(1-ethyl-N-methyl-2-oxoindoline-3-carboxamido)benzoic acid, 1H,3H-spiro[5-chloro-1-methylquinoline-2,4-dione-3,3′-[1]ethylindolin-[2]-one], or 5-Chloro-N-ethyl-3-hydroxy-1-methyl-2,4-dioxo-N-phenyl-1,2,3,4-tetrahydro-quinoline-3-carboxamide.
US08545884B2	Solid pharmaceutical formulations comprising BIBW 2992 The present invention relates to a pharmaceutical dosage form containing the active substance BIBW 2992 as the dimaleate salt, providing an immediate release profile of the active substance, further, the invention relates to compacted intermediates comprising BIBW 2992 dimaleate salt (BIBW 2992 MA2) in form of a powder prepared using a combined roller compaction and sieving step from BIBW 2992 MA2, intermediate blends prepared from said compacted intermediate as well as solid oral formulations providing an immediate release profile of the active substance, made from said compacted intermediate or from said intermediate blends ready for use/ingestion, e.g. capsule and tablet formulations such as uncoated or film-coated tablets prepared by direct-compression, and methods for their production.
US08545883B2	Modular systems for the controlled release of a substance with space and time control An innovative pharmaceutical form for controlled drug release relates to systems obtained by the assembly of individual release modules, of which the capacity to release the drug in time and in space depends on the way in which the modules have been assembled. The modular structure offers high reproducibility of manufacture and flexibility of release.
US08545880B2	Controlled release oral dosage form A once a day bupropion hydrochloride formulation is disclosed.
US08545876B1	Modified drugs for use in liposomal nanoparticles Drug derivatives are provided herein which are suitable for loading into liposomal nanoparticle carriers. In some preferred aspects, the derivatives comprise a poorly water-soluble drug derivatized with a weak-base moiety that facilitates active loading of the drug through a LN transmembrane pH or ion gradient into the aqueous interior of the LN. The weak-base moiety can optionally comprise a lipophilic domain that facilitates active loading of the drug to the inner monolayer of the liposomal membrane. Advantageously, LN formulations of the drug derivatives exhibit improved solubility, reduced toxicity, enhanced efficacy, and/or other benefits relative to the corresponding free drugs.
US08545875B2	Nanolipidic particles Nanolipidic Particles (NLPs) having average mean diameters of 1 nm to 20 nm are made from a precursor solution. NLPs can be loaded with a desired passenger molecule. Assemblies of these particles, called NLP assemblies, result in a vehicle population of a desired size. Single application or multifunction NLP assemblies are made from the loaded NLPs and range in size from about 30 to about 200 nm. A method of using preloaded NLPs to make larger carrier vehicles or a mixed population provides increased encapsulation efficiency. NLPs have application in the cosmetics, pharmaceutical, and food and beverage industries.
US08545872B2	Device for the transdermal administration of a rotigotine base The invention relates to a polymer matrix suitable for the transdermal administration of rotigotine [(−)-5, 6, 7, 8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphtol], containing a matrix for the transdermal administration of rotigotine [(−)-5, 6, 7, 8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1 naphtol], containing a matrix polymer which is supersaturated with a rotigotine base. Said polymer matrix is characterised in that the part of the rotigotine which is not dissolved in the matrix polymer is dispersed in the matrix polymer as amorphous particles having a maximum mean diameter of 30 μm, and the matrix is free of solubilisers, crystallisation inhibitors and dispersants. The invention also relates to a flat device for the transdermal administration of rotigotine, containing the above-mentioned, preferably silicon-based polymer matrix which is supersaturated with rotigotine, and a rear layer which is impermeable to the active ingredient.
US08545868B2	Drug eluting implantable medical device with hemocompatible and/or prohealing topcoat The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases.
US08545866B2	Bioabsorbable polymers Described herein are biocompatible compositions that contain a copolymer and a filler material. In particular, described herein are compositions that include a copolymer and a filler which may be a calcium salt. Also described herein are methods in which the compositions are used to attach soft tissue to bone.
US08545859B2	Use of acrylates copolymer as waterproofing agent in personal care applications The present invention relates to the use of acrylate copolymers, which provide excellent water resistance to personal care products without the undesirable waxy, greasy or heavy feel. Further, these acrylate copolymers are easy for manufacturers to use as they can be easily incorporated into the water phase without special processing.
US08545844B2	Humanized antibodies against human IL-22RA The invention relates to humanized antibodies against human IL-22RA and to their use in the treatment of psoriasis and other immune-mediated diseases such as psoriatic arthritis and atopic dermatitis.
US08545842B2	Polynucleotides encoding IL-17 receptor A antigen binding proteins The present invention relates to IL-17 receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, and the polynucleotide sequences encoding them, as well as host cells, expression vectors, and methods of making IL-17 receptor A antigen binding proteins.
US08545841B2	Methods and compositions for the treatment of cancers and pathogenic infections The subject application provides small compounds that are able to suppress autophagy in various cells. These compounds are useful in augmenting the existing treatments of various cancers and microbial/parasitic infections. Thus, the subject application also provides methods of treating various types of cancers and microbial/parasitic infections. Also provided by the subject application are methods of suppressing the expansion of autophagosomes within cells or individuals and inhibiting the lipidation of autophagy-related protein 8 (Atg8).
US08545840B2	Methods for treating cancer using an immunotoxin The present invention relates to methods for preventing or treating head and neck squamous cell cancer and bladder cancer using an immunotoxin comprising (a) a ligand that binds to a protein on the cancer cell attached to; (b) a toxin that is cytotoxic to the cancer cell. In a specific embodiment, the invention is directed to the prevention or treatment of head and neck squamous cell cancer or bladder cancer using VB4-845, which is a recombinant immunotoxin comprising a humanized, MOC31-derived, single-chain antibody fragment that is fused to a truncated form of Pseudomonas exotoxin A. Also encompassed by the invention are combination therapy methods, including the use of reduced dosages of chemotherapeutic agents, for the prevention or treatment of cancer. Also encompassed by the invention are formulations and methods for direct administration of the recombinant immunotoxin to the carcinoma, for the prevention or treatment of cancer.
US08545839B2	Anti-c-Met antibody The invention relates to a novel antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor both in a ligand-dependent and in a ligand-independent manner, with an improved antagonistic activity, said antibody comprising a modified hinge region.The invention also relates to a composition comprising such an antibody antagonist to c-Met and its use as a medicament for treating cancer.
US08545837B2	Methods and compositions for CNS delivery of iduronate-2-sulfatase The present invention provides, among other things, compositions and methods for CNS delivery of lysosomal enzymes for effective treatment of lysosomal storage diseases. In some embodiments, the present invention includes a stable formulation for direct CNS intrathecal administration comprising an iduronate-2-sulfatase (I2S) protein, salt, and a polysorbate surfactant for the treatment of Hunters Syndrome.
US08545834B2	G-substrate for the treatment and prevention of parkinson's disease The invention features methods and compositions for the treatment and prevention of Parkinson's Disease.
US08545829B2	Pharmaceutical preparations for oral administration, containing ion-exchange resins loaded with active ingredients and intrinsically viscous gelling agents as thickening agents The present invention relates to pharmaceutical preparations for oral administration, comprising one or more active substances bound to an ion exchanger. In order to improve physical stability and acceptance, particularly in animals, a pseudoplastic gel-former thickener is included.
US08545827B2	Conditioning composition for hair The present invention is related to an aqueous conditioning composition for hair comprising at least one alkyl glyceryl ether and at least one arylated silicone. Conditioning composition of the present invention can be in the form of a shampoo, cleansing—conditioning composition, or in the form of a conditioner used after washing hair with cleansing compositions. It has surprisingly been found out that a composition comprising at least one alkyl glyceryl ether and at least one arylated silicone gives hair shine, and hair treated with such a composition looks attractive and has its natural excellent shine, volume and body, elasticity, smoothness and it is easily manageable. Accordingly, the present invention is on a conditioning composition for hair comprising at least one alkyl glyceryl ether and at least one arylated silicone.
US08545823B2	Cosmetic nanocomposites based on in-situ crosslinked POSS materials A cosmetic composition for caring for and/or making up the skin, lips and/or body in the form of a film, which is non-transferable, long-lasting with a comfortable feeling of use to consumers over long periods of wear time. The composition contains graftable POSS which forms a film when it cures in situ. The invention also relates to using such film for preparing a cosmetic composition and a makeup process and makeup kit comprising the product.
US08545820B2	Use of titanium-based materials as bactericides Compositions containing metal ions bound into a titanate are described which have demonstrated an ability to suppress bacterial growth of a number of organisms associated with periodontal disease and caries.
US08545819B2	Oral care toothpowder composition with fluoride ion source A toothpowder oral care composition of fluoride ion source particulate (such as stannous fluoride particulate) dispersed in an oral calcium carbonate abrasive particulate bed is achieved with careful adjustment of the particle sizes of both the fluorinated particulate and the abrasive particulate to achieve a bed of toothpowder where neither the fluorinated particulate or the abrasive particulate will settle to create a localized concentration of the fluoride significantly different from the average concentration of the fluoride throughout the bed.
US08545817B2	Cosmetic composition comprising at least one polysaccharide of λ-carrageenan type in aerosol form, method for the cosmetic treatment of keratinous fibers, and product comprising the composition Disclosed herein is a cosmetic composition for the treatment of keratinous fibers, for example, human keratinous fibers, such as the hair, in the form of an aerosol comprising at least one polysaccharide of lambda-carrageenan type and carbon dioxide as propellant. Also disclosed herein is a cosmetic treatment method for keratinous fibers comprising applying such a composition to the keratinous fibers.
US08545816B2	Benzoic acid ester compounds, compositions, uses and methods related thereto Benzoic acid ester compounds of formula (I): wherein R and R1-R5 have the meanings explained in the description, methods for producing them and use thereof in cosmetic, pharmaceutical, personal care and industrial preparations as sunscreens based on photochemical precursor properties of ultraviolet absorbers.
US08545815B2	VOC-free compressed gas aerosol composition Certain surfactants suitable for use alone to dissolve a water-insoluble component in compositions is described for providing VOC-free compressed gas aerosol compositions. The compositions include water-insoluble component(s), a surfactant and water. The water-insoluble component(s) can be active agent(s), such as fragrance(s) and/or an insecticide(s). The surfactant is present as a single surfactant which, in the absence of a solvent, dissolves or disperses the water-insoluble component(s) and provides a homogenous blend in water which provides a stable compressed gas emulsion. The surfactant is an anionic surfactant or a nonionic surfactant, in particular nonionic alkylpolyglycosides; nonionic cocoglucoside; nonionic alkylene oxide extended chain alkylpolyglycosides; anionic sodium lauryl ether sulfate (SLES), nonionic C13-C15 oxoalcohol ethoxylate with 8 ethylene oxides (EO), nonionic C12-C14 secondary alcohol ethoxylate with 7EO or 12EO, polyethylene glycol (PEG) hydrogenated castor oil wherein the PEG is PEG-60 or PEG-40, polyglyceryl-10 laurate and polyglyceryl-6 caprylate.
US08545813B2	Pre-templated macromolecular architectures with multiple Gd(III) complexes and methods of use as MRI contrast agents The present invention relates to contrast agents for MRI and related methods of use.
US08545812B2	Transport agents for crossing the blood-brain barrier and into brain cancer cells and methods of use thereof The present invention discloses methods and materials for delivering a cargo compound into a brain cancer cell and/or across the blood-brain barrier. Delivery of the cargo compound is accomplished by the use of protein transport peptides derived from Neisseria outer membrane proteins, such as Laz. The invention also provides synthetic transit peptides comprised of the pentapeptide AAEAP. The invention further discloses methods for treating cancer, and specifically brain cancer, as well as other brain-related conditions. Further, the invention provides methods of imaging and diagnosing cancer, particular brain cancer.
US08545808B2	Compositions for radiolabeling diethylenetriaminepentaacetic acid (DTPA)-dextran The subject invention relates to the compositions for radiolabeling Diethylenetriaminepentaacetic Acid (DTPA)-dextran with Technetium-99m and for stabilizing the DTPA-dextran Cold Kit. The composition contains Stannous Chloride ions to reduce 99mTc-pertechnetate, Ascorbic Acid to reduce stannic ions to stannous ions to maintain a reducing environment, α,α-Trehalose to add bulk and to stabilize the lyophilized composition without interfering with the radiochemical yield, and Glycine to transchelate Technetium-99m under highly acidic conditions to facilitate radiolabeling DTPA-dextran with high radiochemical purity. In addition, the invention pertains to methods for making and using the compositions. The reconstitution of the lyophilized composition by 99mTc-pertechnetate, resulting in radiolabeled 99mTc-DTPA-dextran in a composition between pH 3 to 4. This invention contains a Diluent vial, which when used will shift the pH to a moderately acidic pH, which would provide less pain on injection and ease-of-use to clinical practitioners for adjusting its potency.
US08545807B2	Near infrared high emission rare-earth complex The present invention has been created to provide a near infrared high emission rare-earth complex having an excellent light-emitting property in the near infrared region. The near infrared high emission rare-earth complex of the present invention is characterized in that its structure is expressed by the following general formula (1): where Ln(III) represents a trivalent rare-earth ion; n is an integer equal to or greater than three; Xs represent either the same member or different members selected from a hydrogen atom, a deuterium atom, halogen atoms, C1-C20 groups, hydroxyl groups, nitro groups, amino groups, sulfonyl groups, cyano groups, silyl groups, phosphonic groups, diazo groups and mercapto groups; and Z represents a bidentate ligand.
US08545806B2	Compositions and methods for biological remodeling with frozen particle compositions Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
US08545801B1	Method for preparing molecular sieve SSZ-87 This disclosure is directed to a method for preparing a new crystalline molecular sieve designated SSZ-87, which is synthesized using an N,N′-diisopropyl-N,N′-diethylbicyclo[2.2.2]oct-7-ene-2,3:5,6-dipyrrolidinium dication as a structure directing agent.
US08545791B2	Alkyne-assisted nanostructure growth The present invention relates to the formation and processing of nanostructures including nanotubes. Some embodiments provide processes for nanostructure growth using relatively mild conditions (e.g., low temperatures). In some cases, methods of the invention may improve the efficiency (e.g., catalyst efficiency) of nanostructure formation and may reduce the production of undesired byproducts during nanostructure formation, including volatile organic compounds and/or polycylic aromatic hydrocarbons. Such methods can both reduce the costs associated with nanostructure formation, as well as reduce the harmful effects of nanostructure fabrication on environmental and public health and safety.
US08545790B2	Cross-linked carbon nanotubes Cross-linked carbon nanotube arrays forming a three-dimensional structure and methods of use including high thermal conductivity, high strength applications where repeated cycling is known, and chemical storage.
US08545788B2	Low-surface area fumed silicon dioxide powder Fumed silicon dioxide powder with a BET surface area of 20 to 35 m2/g, characterized in that a) the number-based median particle diameter is 60 to 150 nm, and b) the proportion of particles with a diameter of 200 nm or more is at most 10%, and c) the proportion of particles with a diameter of up to 60 nm is at most 20%, based in each case on the total number of particles.
US08545786B2	Manufacture of porous net-shaped materials comprising alpha or beta tricalcium phosphate or mixtures thereof Methods for producing porous tricalcium phosphate net-shaped material are provide. The methods involve preparing a reactant mixture comprising calcium oxide and phosphorus pentoxide in a mole percent ratio that allows the mixture to form tricalcium phosphate upon combustion thereof, forming this mixture into a desired final shape in a die with compression, and carrying out a combustion synthesis therewith. Net-shaped TCP materials of the combustion synthesis, comprising alpha tricalcium phosphate or mixtures of alpha and beta tricalcium phosphate, are optionally further treated to effect transition of the alpha phase to the beta phase. The net-shaped TCP materials can have a uniform or non-uniform porosity.
US08545783B2	Acid gas absorbent, acid gas removal method, and acid gas removal device There is provided an acid gas absorbent having excellent performance of absorbing acid gas such as carbon dioxide, and an acid gas removal device and an acid gas removal method using the acid gas absorbent. An acid gas absorbent of an embodiment contains at least one type of tertiary amine compound represented by the following general formula (1). (In the above formula (1), the cycle A represents a cyclic structure whose carbon number is not less than 3 nor more than 8. R1, R2 and R3 each represent an alkyl group whose carbon number is 1 to 4, and R4 represents a hydroxyalkyl group. R1 and R2 are groups coupled to carbon atoms adjacent to a carbon atom forming the cycle A and coupled to a nitrogen atom.)
US08545780B1	Catalyst materials A catalyst material including a catalyst carrier including a porous alumina support and a hindrance layer on the alumina support, the hindrance layer comprising one or more of a sulfate, carbonate, hydroxide, or oxide of barium, strontium, or calcium is described. The catalyst carrier further includes a rare earth oxide. The catalyst material can further comprise a platinum group metal. The catalyst material is useful for methods and systems of abating pollutants from automotive exhaust gas.
US08545778B2	Sorbents for coal combustion Sorbent compositions containing halogen and calcium are added to coal to mitigate the release of sulfur and/or other harmful elements, including mercury, into the environment during combustion of coal containing natural levels of mercury.
US08545775B2	Reforming exchanger system with intermediate shift conversion A reforming exchanger system for syngas production is provided. The reforming exchanger system can have a first and a second reforming exchanger, each with a shell-and-tube configuration, and a shift reactor located intermediate to the first and second reforming exchangers to reduce carbon monoxide concentration in the outlet gas. Processes for forming syngas using the reforming exchanger systems described herein are also provided.
US08545767B2	Passive one-way valve and microfluidic device This passive one-way valve is used in a connection portion between first and second flow channels, and includes: an inlet portion into which a fluid from the first flow channel flows; an elastic portion for blocking the inlet portion; a rigid portion for supporting the elastic portion from a side opposite to the inlet portion across the elastic portion; a gap portion formed around the rigid portion; and an outlet portion which is in communication with the gap portion for letting the fluid flow out into the second flow channel. Furthermore, the inlet portion is hermetically sealed by the elastic portion being pressed against the inlet portion side by the rigid portion. According to this passive one-way valve, it is possible to provide a simple and inexpensive passive one-way valve without requiring special equipment such as a vacuum pump and pressurized air, and to provide a microfluidic device using the same.
US08545762B2	Sensor for detecting compounds A chemical sensor having a sol-gel material affixable to a predetermined surface, and an indicator within the sol-gel, for detecting and signaling the presence of at least one chemical is provided. Also provided is an indicator for detecting and indicating a presence of at least one chemical. The indicator includes a sol-gel material affixable to a predetermined surface and an indicator within the sol-gel, for detecting and signaling the presence of at least one chemical. There is provided a method of detecting at least one chemical by applying the indicator from above to a predetermined surface of an object and indicating the presence of a chemical. A method of making a chemical sensor encapsulating within a sol-gel a detector capable of detecting and signaling a presence of at least one chemical. A decontaminating agent for removing contaminants from an area, the decontaminating agent being formed of a sol-gel material affixable to a predetermined surface and a decontaminator having an affinity for the contaminants within the sol-gel for decontaminating at least one chemical present in the area.
US08545754B2	Radial design oxygenator with heat exchanger Disclosed is an apparatus for oxygenating and controlling the temperature of blood in an extracorporeal circuit. The apparatus has an inlet and an outlet that is located radially outward from the inlet in order to define a flowpath through the apparatus. The apparatus comprises: a core that is substantially centrally located in the apparatus and to which blood from a patient can be supplied through the inlet; a heat exchanger comprising a plurality of heat transfer elements that are arranged around the core and between which blood from the core can move radially outward; and an oxygenator comprising a plurality of gas exchange elements that are arranged around the heat exchanger and between which blood from the heat exchanger can move radially outward before exiting the apparatus through the outlet.
US08545744B2	Fibre-reinforced composite moulding and manufacture thereof Method of manufacturing a fiber-reinforced composite molding, the method comprising the steps of: (a) disposing at least one layer of fibrous reinforcing material within a mold; (b) disposing at least one pre-preg layer adjacent to the fibrous reinforcing material, the pre-preg layer comprising fibrous reinforcement at least partially impregnated with uncured first resin material, to form a laminar assembly of the at least one layer of fibrous reinforcing material and the at least one pre-preg layer within the mold; (c) applying a vacuum to the assembly; (d) infusing a flowable uncured second resin material, under the vacuum, into the at least one layer of fibrous reinforcing material; and (e) curing the first and second resin materials at least partially simultaneously to form the fiber-reinforced composite molding which comprises at least one first structural portion formed from the fibrous reinforcement and the cured first resin material bonded to at least one second structural portion formed from the at least one layer of fibrous reinforcing material and the cured second resin material.
US08545741B2	Method of manufacturing microstructure Provided are methods of manufacturing microstructures, in which at least one viscous composition each containing at least one active ingredient is disposed directly or indirectly on a first substrate and/or a second substrate and the viscous composition(s) is elongated between the first and second substrates. The methods are simpler and more cost-effective.
US08545739B2	Method and apparatus for preparing micro-particles of polysaccharides The present invention relates to a method for the production of micro-particles of polysaccharides. The method includes preparing a feeding solution and a gelifying liquid to collect nebulized jets of the feeding solution. The feeding solution contains at least one polymer capable of forming micro-particle structures and at least one biologically active substance. The feeding solution is pressurized inside an air-less nebulizing unit and then nebulized through the unit itself so as to generate nebulized jets impacting the surface of the gelifying liquid.
US08545738B2	Stabilized photochromic ink for reusable paper annotation Provided are ink compositions, methods for making photochromic inks, and methods of using the photochromic inks for erasable media annotation. In accordance with various embodiments, there is an ink composition including a carrier medium and one or more photochromic species in the carrier medium, wherein each of the one or more photochromic species can be selected from the group consisting of monomeric photochromic molecules, photochromic oligomers, and photochromic polymers, and wherein each one of the one or more photochromic species exhibits a reversible transition from a colorless state to a colored state upon exposure to a radiant condition wherein the radiant condition can be selected from the group consisting of a radiant energy and a combination of a radiant energy and thermal energy.
US08545737B2	Cellulose acetate film, polarizing plate, and liquid crystal display device Disclosed are a cellulose acetate film characterized by comprising cellulose acetate that has a degree of acetylation of 51.0-56.0% and a compound represented by Formula (1) and having a total average degree of substitution of 6.1-6.9, a polarizing plate capable of maintaining excellent visibility, and a liquid crystal display device having excellent visibility and viewing angle characteristics. (In Formula (1), R1 to R8 may be the same or different and each represents an (un)substituted alkylcarbonyl or an (un)substituted aryl carbonyl).
US08545734B2	Methods for photovoltaic absorbers with controlled group 13 stoichiometry This invention includes processes for making a photovoltaic absorber layer having a predetermined stoichiometry on a substrate by depositing a precursor having the predetermined stoichiometry onto the substrate and converting the deposited precursor into a photovoltaic absorber material. This invention further includes processes for making a photovoltaic absorber layer having a predetermined stoichiometry on a substrate by (a) providing a polymeric precursor having the predetermined stoichiometry; (b) providing a substrate; (c) depositing the precursor onto the substrate; and (d) heating the substrate.
US08545733B2	Methods of making glass-crystalline particles including a glass component and a crystalline component Disclosed is a process for the manufacture of glass-crystalline particles comprising a glass component and a crystalline component comprising the steps of: a) providing a precursor solution comprising a solvent, a glass component composition, and a crystalline component composition; b) forming an aerosol comprising finely divided droplets of the precursor solution, wherein the droplet concentration which is below the concentration where collisions and subsequent coalescence of the droplets results in a 10% reduction in droplet concentration; c) heating the aerosol wherein, upon heating, glass-crystalline particles are formed, wherein the glass-crystalline particles comprise a glass component and a crystalline component, and wherein the crystalline component comprises one or more metal oxides; and d) isolating the glass-crystalline particles.
US08545728B2	Method for preparing electrostatic dissipative polymer A method for preparing an electrostatic dissipative polymer and a blend of a thermoplastic polymer and the ESD polymer is disclosed. The method for preparing an electrostatic dissipative polymer includes the step of polymerizing the electrostatic dissipative polymer in the presence of a reactive solvent and lithium salt dissolved in the reactive solvent, wherein the amount of the reactive solvent is from 0.1 to 20 weight parts based on 100 weight parts of the produced electrostatic dissipative polymer, the amount of lithium salt is from 0.1 to 5 weight parts based on 100 weight parts of the produced electrostatic dissipative polymer, and the reactive solvent is aliphatic glycol having from 2 to 8 carbon atoms and having a primary alcohol group, or aromatic glycol having from 6 to 10 carbon atoms.
US08545721B2	UV coating composition for LED color conversion A UV coating composition for LED color conversion including: 25 wt % to 97 wt % of a UV curable resin; and 3 wt % to 75 wt % of a phosphor. The composition enables emission of white light using only a white LED lens or a light guide plate without affecting a blue, violet or UV LED, thereby eliminating a need for a white LED. Further, users of a LED including the composition can perform direct and easy adjustment of the intensity of white light to obtain a desired intensity by replacing a conventional LED lens. The LED lens provides soft and comfortable lighting which effectively reduces glare caused by high brightness white LED lighting. Moreover, the composition slows deterioration of a lighting device and makes possible a light guide plate having a simple and thin structure.
US08545718B2	Wholly aromatic thermotropic liquid-crystal polyester resin composition, molded object, and LED reflector A wholly aromatic thermotropic liquid-crystal polyester resin composition, comprising 5 to 40 parts by volume of titanium oxide (B) and 5 to 40 parts by volume of barium sulfate (C) with respect to 100 parts by volume of a wholly aromatic thermotropic liquid-crystal polyester (A); wherein the total of the (B) component and the (C) component with respect to 100 parts by volume of the (A) component is 15 to 45 parts by volume.
US08545715B1	Chemical mechanical polishing composition and method A chemical mechanical polishing composition and method is provided, wherein the low-k dielectric material removal rate remains stable following the polishing of a 110th polished wafer in a plurality of wafers to be polished.
US08545714B2	Hexagonal ferrite magnetic particle and method of manufacturing the same, and magnetic recording medium An aspect of the present invention relates to a method of manufacturing a hexagonal ferrite magnetic particle comprising melting an Al-containing starting material mixture to prepare a melt and quenching the melt to obtain an amorphous material; subjecting the amorphous material to heat treatment to cause a hexagonal ferrite magnetic particle to precipitate in a product obtained by the heat treatment; collecting a hexagonal ferrite magnetic particle by subjecting the product to treatment with an acid and washing, wherein the hexagonal ferrite magnetic particle collected has a particle size ranging from 15 to 30 nm, comprises 0.6 to 8.0 weight percent of Al, based on Al2O3 conversion, relative to a total weight of the particle, and Al adheres to a surface of the hexagonal ferrite magnetic particle.
US08545711B2	Processing method A processing method performs a predetermined process to an object by supplying a process gas at a prescribed flow rate into a process container to which a gas supply unit and an exhaust system are connected. The processing method includes a first process of setting the gas supply unit to supply a process gas at a flow rate greater than the prescribed flow rate of a predetermined process for a predetermined short time from a gas channel while exhausting an atmosphere in the process container through the exhaust system; and a second process of setting the gas supply unit to supply the process gas at the prescribed flow rate from the gas channel after the first process is completed.
US08545704B2	Method for recovering amine from amine-containing waste water Provided is a method for recovering high-concentration and high-purity amine from amine-containing waste water generated from nuclear power plants and thermal power plants. The method includes: capturing amine and concentrating waste water using a cation exchange resin; separating amine from the concentrated amine-containing waste water; and carrying out further separation of amine via distillation. The method may be applied to treat amine, which causes an increase in biochemical oxygen demand (BOD) and total nitrogen concentration, drastically at the time of its generation from waste water of nuclear power plants and thermal power plants. In this manner, the method may prevent an increase in load of existing waste water treating plants and avoid a need for modifying the equipment in the existing plants. In addition, the method disclosed herein may allow recovery and reutilization of amine, injected continuously to prevent corrosion of water/vapor circulation systems of nuclear power plants and thermal power plants, thereby improving the cost-efficiency in such power plants.
US08545703B1	Production of glycerin from feedstock Process and steps for the production of biodiesel and/or glycerin from feedstock are provided.
US08545695B2	Water provisioning system for kitchen The water provisioning system mainly contains a selection switch, a water volume switch, a human-machine interface (HMI), a RO waste water recycling device, an electromagnetic valve, a RO water purification device, an antichlor device, an aeration pipe assembly, a first ozone module, and a second ozone module. The selection switch selects a type of water to use. The RO water purification device filters water from a low-temperature water source, stores purified water in a storage barrel, and provides high-quality drinking water. The 70% water from the RO water purification process that fails the drinking water standard is recycled through the RO waste water recycling device. The low-temperature water source is connected to an antichlor device and the water is therefore dechlorinated. The first and second ozone modules are used to produce ozonated water and to release ozone through the aeration pipe assembly into the kitchen cabinet for deodorization and sterilization.
US08545693B2	Analyte measurment method and system Described and illustrated herein are systems and exemplary methods of operating a multianalyte measurement system having a meter and a test strip. In one embodiment, the method may be achieved by applying a test voltage between a reference electrode and a first working electrode; measuring a first test current, a second test current and a third test current at the working electrode with the meter after a blood sample containing an analyte is applied to the test strip; estimating a hematocrit-corrected analyte concentration from the first, second and third test currents; and displaying the hematocrit-corrected analyte concentration.
US08545689B2	Gallium electrodeposition processes and chemistries Solutions and processes for electrodepositing gallium or gallium alloys includes a plating bath free of complexing agents including a gallium salt, an indium salt, a combination thereof, and a combination of any of the preceding salts with copper, an acid, and a solvent, wherein the pH of the solution is in a range selected from the group consisting of from about zero to about 2.6 and greater than about 12.6 to about 14. An optional metalloid may be included in the solution.
US08545686B2	Electrophoretic apparatus and electrophoretic method The present invention relates to detection of an emission spectrum by irradiating excitation light onto a plurality of electrophoretic paths and dispersing fluorescent light output from the electrophoretic paths in a direction approximately vertical to an electrophoretic direction. According to the invention, since an emission spectrum to be detected does not substantially change over time, it becomes possible to make observed emission spectrums completely correspond to various fluorescent dyes or various bases.
US08545685B2	Cleaning process of producing lactic acid Provided is a cleaning process of producing lactic acid. Firstly saccharification liquid is prepared through saccharated materials, then fermented with nutritive materials and lactic acid bacteria, and liquid alkali is used to adjust the pH. The fermentation broth is filtrated with porous membrane, and the lactic acid bacteria in the interception liquid are then reintroduced into the porous membrane for recycling. The permeate from porous membrane is subjected to nanofiltration to be decolored and purified. The concentrated solution from nanofiltration and the cleaning liquid from fermentation tank and its affiliated equipment are filtrated and sterilized by using ceramic membrane, and then are reintroduced into the fermentation unit for recycling. The permeate from nanofiltration is then subjected to bipolar electrodialysis system to prepare lactic acid, and the liquid alkali produced at the same time is reintroduced into the fermentation tank for recycling. The lactic acid is finally concentrated by using vacuum distillation. The process recycles the bacteria in the liquid alkali and matured fermentation broth, and is characterized by low material consumption and emission, low pollution, reduced cost and cleanness and environmentally protection of the whole production process.
US08545682B2	Swimming pool cleaning and sanitizing system An in-line cleaning and sanitation apparatus for cleaning a liquid, the apparatus including electronic oxidation means to increase the oxidation reduction potential of the liquid, and ionization means to produce ions having an algaecidal or bactericidal effect into the liquid, in that order together with ultrasonic cleaning means to introduce sound waves into the liquid, and wherein the ionization means, the ultrasonic cleaning means and the electronic oxidation means are operated simultaneously for a period to clean and sanitize the liquid in the absence of added salt, chlorine or other chemicals.
US08545679B2	System and method for recovery of hydrocarbons in tar sands A system for recovering hydrocarbons from tar sands includes a heated enclosure 66, one or more input conveyors 60, 67 move tar sands through the heated enclosure, provide a flow line with a temperature gradient of at least 150 F.°, and mechanically move the tar sands along the flow line. A heated rotary drum 74 is in fluid communication with the flow line, and condenser unit 94, 98 receive vapors from the flow line and the rotary drum and output hydrocarbons. One or more discharge conveyors 76 discharge stripped sands from the rotary drum. Control valves 80, 82 seal a vacuum downstream from the discharge conveyors, and control valves 34, 46 seal vacuum upstream from the one or more input conveyors. Various types of vacuum pumps may be used to maintain a selected vacuum between the control valves.
US08545678B2	Apparatus for manufacturing a hygiene paper product Method of manufacturing a hygiene paper product in form of a continuous paper web (W)of sheets partly separated by perforation lines (9) and wound to a log of predetermined longitudinal length, providing a continuous paper web (W), moving the continuous paper web in a direction of its longitudinal extension, providing at least one embossed pattern on the continuous paper web, providing in the area of an embossing station at least one mark (6, 7) onto the continuous paper web, which mark (6, 7) is in register to the embossed pattern, sensing the mark and controlling perforating means for registering the perforation lines (9) with the embossed pattern thereby imparting perforation lines to the continuous paper web in predetermined longitudinal distances, winding up the resulting web to logs, and cutting the log into rolls.
US08545676B2	Fabric-creped absorbent cellulosic sheet having a variable local basis weight An absorbent cellulosic sheet includes a papermaking-fiber reticulum. The paper-making-fiber reticulum includes a plurality of fiber-enriched regions that are oriented in a cross-machine direction (CD) of the sheet, and the fiber-enriched regions have (i) a local basis weight and (ii) papermaking fibers that are oriented in the CD of the sheet. The paper-making-fiber reticulum further includes a plurality of linking regions that link corresponding ones of the fiber-enriched regions together in linking directions. The linking regions have (i) basis weights that are lower than those of the corresponding ones of the fiber-enriched regions and (ii) papermaking fibers that are oriented in the linking directions.
US08545675B2	Apparatus for separating particles and methods for using same An apparatus suitable for separating particles and methods for using such apparatus are provided.
US08545666B2	Labeling apparatus for applying wrap labels and method A labeling apparatus for applying wrap labels includes a first conveyor section and a second conveyor section aligned with the first conveyor section thereby defining a conveying surface along which a package is conveyed in a conveying direction. The first conveyor section is spaced from the second conveyor section in the conveying direction thereby defining a gap between the first conveyor section and the second conveyor section. A label conveyor is located at least partially below the conveying surface having a vertical orientation to deliver a wrap label upwardly through the gap between the first and second conveyor sections. A wiper assembly is located above and spaced vertically from the conveyor surface to define a space between the wiper assembly and the conveying surface. The wiper assembly is arranged to receive a leading edge of the wrap label when it is delivered from the label conveyor and to position the leading edge of the wrap label such that the wrap label spans the space between the wiper assembly and the conveying surface for delivery of an adhesive surface of the wrap label over an edge of the package as the package passes through the space.
US08545664B2	Tape applying device, tape holding unit, and tape applying method A tape applying device for applying electrically conductive tape onto a board includes: a applying head for pressing the conductive tape; a tape holding unit including a reel section having a feed reel for feeding the conductive tape laminated with a separator and a wind-up reel to which the separator is to be wound up, and a tape guide section for guiding the conductive tape along with the separator to a position of pressing by the applying head; and a base section which has a tape guide driving unit for moving up and down the tape guide section, and to and from which the tape holding unit is fittable and removable. The tape guide section, while in a fitted state of being fitted to the base section, is separated from the reel section and moved up and down by driving force of the tape guide driving unit.
US08545660B1	Bonding apparatus and method A bonding apparatus and method holds first and second bodies peripherally, one above the other, on respective shelves. A lower heat-transfer body is configured to lift the first body from below and press the first and second bodies against an upper heat-transfer body to enable bonding between the first and second bodies.
US08545657B2	Methods for tape fabrication of continuous filament composite parts and articles of manufacture thereof A method for forming a composite structure according to one embodiment includes forming a first ply; and forming a second ply above the first ply. Forming each ply comprises: applying a bonding material to a tape, the tape comprising a fiber and a matrix, wherein the bonding material has a curing time of less than about 1 second; and adding the tape to a substrate for forming adjacent tape winds having about a constant distance therebetween. Additional systems, methods and articles of manufacture are also presented.
US08545655B2	Method for producing print A method for producing a print includes a step of thermally bonding a thermally transferrable image-protecting layer onto an image surface of an image-receiving sheet so as to form a protective layer. In this step, thermal energy applied is changed so that the resulting protective layer has a first glossy region and a second glossy region having a glossiness lower than that of the first glossy region. The first glossy region has a glossiness a, which is a 20° mirror-surface glossiness measured according to Japanese Industrial Standard Z8741. The second glossy region has a glossiness b, which is a 20° mirror-surface glossiness measured according to Japanese Industrial Standard Z8741. The value obtained by subtracting the glossiness b from the glossiness a is 60 or more.
US08545652B1	Impact resistant material A method of making a tile, the method comprising: providing a plurality of nano-particles, wherein the plurality of nano-particles comprises a plurality of ceramic nano-particles; and performing a spark plasma sintering (SPS) process on the plurality of nano-particles, thereby forming a tile comprising the plurality of nano-particles, wherein the nano-structure of the nano-particles is present in the formed tile. In some embodiments, the tile is bonded to a ductile backing material.
US08545650B2	Method of repairing a composite structure A surrogate patch assembly for a rework area of a structure comprises a surrogate patch body which may be formed of a material for drawing moisture from the rework area. The patch assembly may include a sensor mounted to the surrogate patch body. The sensor may comprise a thermal sensor for sensing the temperature of the rework area and the surrogate patch body. The sensor may comprise a moisture sensor for sensing moisture drawn into the surrogate patch body.
US08545648B2	Method for producing heat insulating laminate structure, heat insulating laminate structure, and transparent laminate film for the same Disclosed is a method for producing a heat insulating laminate structure having an excellent solar radiation shielding capability as well as an excellent radio wave transparency. The method includes placing a transparent laminate film between two transparent substrates, the transparent laminate film having on at least one side of a transparent polymer film a laminated layer structure in which a metal oxide layer containing an organic component and a metal layer are laminated and grooves having widths of 30 μm or less are formed with dividing the metal layer; bonding the two substrates to each other through the transparent laminate film under application of a pressure; and promoting division of the metal layer in the transparent laminate film by the applied pressure to increase an overall surface resistance.
US08545645B2	Stress free steel and rapid production of same A method of producing steel with reduced internal stress concentrations is disclosed. In an embodiment, hot steel is shaped by a rolling mill. The resultant steel product is bundled as soon as practicable and the bundle is allowed to cool. Vibration energy is applied to the bundle of steel product so that internal stress concentrations within the steel product are relieved. In an embodiment, a plurality of bundles are stored on a rack and the rack is vibrated, the vibrations being transmitted to the plurality of bundles so that undesired internal stress concentrations within the steel products are relieved. Alternatively, magnetics may be used to relieve the undesired internal stress concentrations within the steel products. Thus, improved steel is produced as well as improved steel that can be produced more rapidly than known techniques.
US08545637B2	Cleaning device and cleaning method A cleaning device (1) performs a cleaning of an article by blowing a cleaning medium (5) by an air stream onto the article (4). The cleaning device (1) includes a cleaning tank (6) that forms a space for the cleaning medium (5) to be blown, which includes an opening; a holding unit (3) that holds the article (4) at the opening; a pool member (19) that is arranged on an outer edge of the opening with a clearance between the pool member (19) and the article (4); and a cleaning-medium collecting unit (8) that brings the cleaning medium (5) leaked out of the outer edge and accumulated in the clearance back into the cleaning tank (6).
US08545634B2	System and method for cleaning a conditioning device A system for cleaning a conditioning device to improve the efficiency of the conditioning of a polishing pad using the conditioning device as part of a chemical-mechanical polishing process, the system comprising a conditioning device; a fluid dispenser arranged to dispense a fluid on the conditioning device; and an acoustic nozzle arranged to emit a megasonic or ultrasonic signal at the conditioning device while the fluid dispenser is dispensing the fluid on the conditioning device.
US08545628B2	Temperature-controlled purge gate valve for chemical vapor deposition chamber The present invention relates to methods and apparatus that are optimized for producing Group III-N (nitrogen) compound semiconductor wafers and specifically for producing GaN wafers. Specifically, the methods relate to substantially preventing the formation of unwanted materials on an isolation valve fixture within a chemical vapor deposition (CVD) reactor. In particular, the invention provides apparatus and methods for limiting deposition/condensation of GaCl3 and reaction by-products on an isolation valve that is used in the system and method for forming a monocrystalline Group III-V semiconductor material by reacting an amount of a gaseous Group III precursor as one reactant with an amount of a gaseous Group V component as another reactant in a reaction chamber.
US08545627B2	Zirconium and hafnium boride alloy templates on silicon for nitride integration applications Semiconductor structures are provided comprising a substrate and a epitaxial layer formed over the substrate, wherein the epitaxial layer comprises B; and one or more element selected from the group consisting of Zr, Hf and Al and has a thickness greater than 50 nm. Further, methods for integrating Group III nitrides onto a substrate comprising, forming an epitaxial buffer layer of a diboride of Zr, Hf, Al, or mixtures thereof, over a substrate; and forming a Group III nitride layer over the buffer layer, are provided which serve to thermally decouple the buffer layer from the underlying substrate, thereby greatly reducing the strain induced in the semiconductor structures upon fabrication and/or operation.
US08545626B2	Nitride semiconductor crystal and its production method A method for efficiently producing a plate-like nitride semiconductor crystal having the desired principal plane in a simple method is provided. A raw material gas is fed to a seed crystal in which a ratio (L/W) of length L in a longitudinal direction and maximum width W, of a plane of projection obtained by projecting a crystal growth face on the seed crystal in a growth direction is from 2 to 400, and the maximum width W is 5 mm or less, thereby growing a plate-like semiconductor crystal on the seed crystal.
US08545620B2	Cement accelerator The invention relates to an inorganic binder system comprising a) calcium silicate cement, b) calcium aluminate cement, c) at least one trifunctional polyalkylene glycol and d) optionally calcium sulphate. Additionally disclosed is the use of at least one polyalkylene glycol as an accelerator for an inorganic binder system comprising a) calcium silicate cement, b) calcium aluminate cement and d) optionally calcium sulphate.
US08545618B2	Stable aqueous silica dispersions The invention relates to silica dispersions that have a long shelf-life, to a method for producing the same and to their use in the construction industry as concrete admixtures and in the paper industry for producing or coating paper.
US08545617B2	Neutralizing and co-dispersion agent with strong capacity for developing coloring power, and paints and pigment concentrates containing same The invention relates to the use, as neutralizing and/or co-dispersion agent in a paint and/or as agent for developing the coloring power of pigment(s) in a white paint base that we wish to color, of at least one hydroxylated secondary or tertiary amine.The invention also relates to pigment concentrates and paints containing at least one hydroxylated secondary or tertiary amine.
US08545614B2	Additives comprising cellulose ethers for ceramics extrusion The present invention relates to specific additives comprising cellulose ether, a plasticizer, at least one defoamer and water having a pH greater than 7 for improving the extrudability of clay ceramic masses and other masses which set as a result of baking or sintering, a corresponding extrusion process, the extrudates and their use.
US08545612B1	Phase change ink compositions and sulfonated compounds for use in the same A phase change ink composition, comprising an anti-drool additive to prevent and/or reduce printhead and nozzle contamination in ink jet printers caused by drooling and fouling of the faceplate by the ink. In particular, there is provided sulfonated small molecules for use in phase change ink compositions and which are compatible with phase change ink components.
US08545607B2	Pleatable composite filter media A pleatable, high efficiency composite gas filtration media is provided. The media includes an essentially boron free chopped strand glass backer layer and media layer comprising a synthetic material. The composite media exhibits excellent pleatability, low boron out gassing, and low organic out gassing, with filtration performance comparable to existing commercial membrane composites.
US08545603B2	Method to improve recovery and efficiency of adsorption processes using reversible blowers The present invention provides for a method utilizing adsorber bed(s) and reversible blower(s) operating in a vacuum pressure swing adsorption separation process to separate gases. The process is designed to provide a safer and more cost-effective adsorption system that captures and utilizes energy typically wasted during equipment transitions thereby achieving overall higher power efficiency.
US08545600B2	Method for the deposition of paint overspray, and deposition liquid In a method for removing solids from overspray produced when painting objects, the overspray is absorbed by an air flow and is conducted to a deposition surface, across which a deposition liquid flows and where a large part of at least the solids is transferred into the deposition liquid, is discharged by said deposition liquid, and is removed from the liquid by means of a deposition process. A deposition liquid is used and disclosed which comprises a detackifying medium and an optional suspending fluid, paint overspray particles being detackified using the detackifying medium.
US08545597B2	Method for operating a blast furnace and blast furnace installation A method for operating a blast furnace and a corresponding blast furnace, the method including recovering top gas from the blast furnace, submitting at least a portion of the top gas to a recycling process, and feeding the recycled top gas back into the blast furnace, where the recycling process includes feeding the recovered top gas to a reformer unit, feeding volatile carbon containing material to the reformer unit, proceeding to flash gasification of the volatile carbon containing material in the reformer unit, at a temperature between 1100 and 1300° C., and thereby producing devolatized carbonaceous material and synthesis gas, and allowing the devolatized carbonaceous material and synthesis gas to react with the recovered top gas.
US08545596B2	Methods for manufacturing alloyed zinc powders with pierced particles for alkaline batteries The invention concerns alloyed zinc powders for alkaline batteries and a method to manufacture such powders. The powders are characterized by the presence of particles pierced with at least one hole. This appears to benefit the high drain discharge capacity while preserving the process ability of the powder, and the shelf life and the gassing behavior of the batteries. The invented powders can be manufactured using centrifugal atomization in a cooled, oxygen-depleted atmosphere.
US08545595B2	Photon induced formation of metal comprising elongated nanostructures The preferred embodiments provide a method for forming at least one metal comprising elongated nanostructure on a substrate. The method comprises exposing a metal halide compound surface to a photon comprising ambient to initiate formation of the at least one metal comprising elongated nanostructure. The preferred embodiments also provide metal comprising elongated nanostructures obtained by the method according to preferred embodiments.
US08545593B2	Direct processing of metallic ore concentrates into ferroalloys A method for producing liquid ferroalloy by direct processing of manganese and chromium bearing iron compounds, by the steps: of mixing carbonaceous reductant, fluxing agent, and a binder with materials such as iron sands, metallic oxides, manganese-iron ore concentrates and/or chromium-iron ore concentrates and silica sands, to form a mixture; forming agglomerates from the mixture; feeding the agglomerates to a melting furnace with other materials; melting the feed materials at a temperature of from 1500 to 1760° C. and forming a slag and hot metal; removing the slag; tapping the hot metal as liquid ferroalloy, and utilizing the off-gases from the melting furnace as combustion fuel to drive a turbine and to generate electricity.
US08545591B2	Potassium sulfite/potassium bisulfite (KS/KBS) liquid as starter, side-dress, broadcast, foliar and fertigation fertilizers The present invention provides a new liquid fertilizer comprised of potassium sulfite and potassium bisulfite, with neutral to slightly alkaline pH, relatively lower salt index and potentially lower phytotoxicity damage compared to other sources of potassium and sulfur products applied in equal amounts as a starter fertilizer. More specifically, the present invention further relates to methods for fertilizing using a composition of potassium sulfite and potassium bisulfite, particularly as a starter fertilizer, in-furrow fertilizer, side dress fertilizer, and for foliar, broadcast, soil injection and fertigation applications. The fertilizer composition is comprised primarily of potassium sulfite and potassium bisulfite (with the fertilizer grade of 0-0-23-8S).
US08545586B2	Air cleaner element holding structure The present invention relates to an air cleaner element holding structure for an air cleaner device for use in filtering intake air for an engine. The air cleaner device includes an air cleaner element and an element holder, provided in an air cleaner case. The air cleaner element includes at least a pair of element support plates and the element holder includes at least a pair of circular plates. The air cleaner case includes an intake duct facing an inner circumferential side of the air cleaner element for conducting air thereto. Each of the support plates has an outer diameter that is larger than that of the air cleaner element. The element support plates support the air cleaner element in such a manner that both ends, in the axial direction, of the element holder contact an inside surface, in the axial direction, of the element support plates.
US08545585B2	Filter element for pulse cleaning and methods To improve in pulse cleaning of filters, a filter element includes a media pack of Z-media having first and second opposite flow faces and a side wall extending between the first and second flow face. A gasket is secured to the side wall. The gasket has a sealing portion and an attachment portion. The sealing portion has a flat surface at least one inch long and is located between being planar with and 0.5 inches recessed from the first flow face, inclusive.
US08545584B2	Glass fiber structure designed to reinforce bonded abrasive articles The invention relates to a structure based on glass fiber coated with a resin composition designed to reinforce bonded abrasive articles, the resin composition including the following constituents in the proportions indicated, expressed in percentage by weight of solid matter: 75 to 98% of a mixture of at least one novolac having a glass transition temperature lower than or equal to 60° C. and at least one novolac having a glass transition temperature above 60° C., 0.5 to 10% of at least one wax, 0 to 3.5% of at least one plasticizing agent.
US08545583B2	Method of forming a flexible abrasive sheet article Flexible abrasive sheet articles having precision thickness flat-topped raised island structures that are coated with a monolayer of equal sized abrasive agglomerate are described. Methods of producing high quality equal-sized spherical shaped composite abrasive agglomerate beads containing small diamond abrasive particles are described. Beads are produced by level-filling fine mesh screens or perforated sheets with a water based metal oxide slurry containing abrasive particles and then using a fluid jet to eject the abrasive slurry lumps from the individual screen cells into a dehydrating environment. Surface tension forces form the ejected liquid lumps into spheres that are solidified and then heated in a furnace to form ceramic beads. These porous ceramic abrasive beads can be bonded directly onto the flat planar surface of a flexible backing material or they can be bonded onto raised island surfaces to form rectangular or disk abrasive sheet articles. Abrasive articles having equal sized abrasive beads are particularly suited for lapping and raised island articles are suited for high speed lapping. Non-abrasive equal-sized beads can also be formed using this simple bead manufacturing process, which requires only a very low capital investment.
US08545578B2	System and method for using board plant flue gases in the production of syngas Disclosed is an apparatus and method for capturing the hot humid gases from a gypsum board dryer and utilizing those gases in the production of a synthetic gas (referred to as “syngas”). The syngas produced can then be utilized within a gypsum board plant to reduce the amount of natural gas needed.
US08545564B2	Intervertebral spacer device having an articulation member and housing Instrumentation for implanting an artificial intervertebral disc includes static trials and a dynamic trial for determining the appropriate size of disc to be implanted, static trial holders for manipulating the static trials, inserter/impactors for inserting and removing the static trials and for inserting the artificial intervertebral discs, repositioners/extractors for repositioning and extracting the static trials or the artificial intervertebral discs, and a leveler for setting the proper position of the artificial intervertebral disc. Methods for using the same are also disclosed. Features for artificial intervertebral discs and intervertebral spacer devices useful for manipulation by the instrumentation are also disclosed.
US08545559B2	Modified metal materials, surface modifications to improve cell interactions and antimicrobial properties, and methods for modifying metal surface properties The present disclosure is directed to modified metal materials for implantation and/or bone replacement, and to methods for modifying surface properties of metal substrates for enhancing cellular adhesion (tissue integration) and providing antimicrobial properties. Some embodiments comprise surface coatings for metal implants, such as titanium-based materials, using (1) electrochemical processing and/or oxidation methods, and/or (2) laser processing, in order to enhance bone cell-materials interactions and achieve improved antimicrobial properties. One embodiment comprises the modification of a metal surface by growth of in situ nanotubes via anodization, followed by electrodeposition of silver on the nanotubes. Other embodiments include the use of LENS™ processing to coat a metal surface with calcium-based bioceramic composition layers. These surface treatment methods can be applied as a post-processing operation to metallic implants such as hip, knee and spinal devices as well as screws, pins and plates.
US08545554B2	Intraocular injector An intraocular injector includes a syringe body having open-ended cone disposed in one end thereof along with a piston disposed in the body. A transparent implant holder having a lumen therein is aligned with an open-ended cone, a needle include a proximal end and a distal end with a bevel disposed on the distal end of the needle. A plunger affixed to the piston and slidable within a holder lumen and needle lumen is provided for injecting solid intraocular implants into an eye. A cylindrical syringe body shape facilitates control over the needle bevel orientation during injection of the implant into the eye.
US08545553B2	Over-wire rotation tool Apparatus is provided that includes an implant structure, which includes a contracting mechanism, which includes a rotatable structure, arranged such that rotation of the rotatable structure contracts the implant structure. A longitudinal member is coupled to the contracting mechanism. A tool for rotating the rotatable structure is configured to be guided along the longitudinal member, to engage the rotatable structure, and to rotate the rotatable structure in response to a rotational force applied to the tool. Other embodiments are also described.
US08545552B2	Systems and methods for transcatheter aortic valve treatment Devices and methods are configured to allow transcervical or subclavian access via the common carotid artery to the native aortic valve, and implantation of a prosthetic aortic valve into the heart. The devices and methods also provide means for embolic protection during such an endovascular aortic valve implantation procedure.
US08545545B2	Stent with flexible hinges A helical stent includes at least one helical winding. Each helical winding includes a plurality of alternating long struts and short struts, ends of at least some of the long struts being joined to an end of an adjacent short strut by a flexible hinge arrangement, the struts being substantially rigid. The stent also includes at least one interconnection member connecting a hinge arrangement on one turn of the at least one winding with a hinge arrangement on an adjacent turn of the at least one winding. Fewer than all hinge arrangements on the at least one helical winding are connected to other hinge arrangements by an interconnection member.
US08545540B2	Bone plate with pre-assembled drill guide tips Removable drill guide tips are pre-assembled into threaded holes of a bone plate. The tips may be used with an extension to together function as a conventional drill guide. After drilling, the extension or another tool is used to remove the tips from the plate. According to another use, the tip is used as a guide for a drill bit without any additional extension and then removed with a tool.
US08545538B2	Devices and methods for inter-vertebral orthopedic device placement Within a given spinal segment, the stable vertebral level is identified. Within the lower lumbar spine, that level is most commonly at the sacrum. A bone fastener is rigidly affixed to the stable spinal segment and an interconnecting member is rigidly affixed to the bone fastener so as to form a cantilever construct. Vertebral bodies that exhibit aberrant spinal motion and/or mal-alignment relative to the stable segment are then attached to the interconnecting member using non-rigid bone fastener(s). The motion profile of the dynamic fastener can be varied and may be selected to provide the desired vertebral motion characteristics. The interconnecting member may be rigid or it may be alternatively made rigid parallel to the direction of greatest instability and non-rigid in the other planes.
US08545536B2	Device and method for fixating a suture anchor in hard tissue A tool for fixating a suture anchor in a hard tissue opening with the aid of a material having thermoplastic properties and energy transmitted to the suture anchor for in situ liquefaction of at least part of the material having thermoplastic properties, includes a distal face, an axial channel and a substantially tube-shaped interface piece fitting into the axial channel of the tool, wherein the axial channel and a proximal end of the interface piece are equipped with catch elements cooperating for catching the interface piece in the axial channel when the interface piece is moved in a proximal direction in the axial channel.
US08545532B2	Device and method for treating a vessel A device and method for treating bodily diseases and/or conditions, for example, varicose veins, tumors and aneutisms including for example insertion of a blocking device toward a target destination using a catheter and delivery of sclerosing or other agents to the vessel while maintaining minimal, for example zero pressure in the treatment area, The blocking device may prevent treatment materials, embolisms, debris etc., from entering the upstream section of vessel. The blocking device may include, for example, a cap or other concave shape and may be expandable or extendible towards the vessel walls.
US08545526B2	Retrieval systems and methods for use thereof The devices and methods described herein relate to improved structures for removing obstructions from body lumens. Such devices have applicability in through-out the body, including clearing of blockages within the vasculature, by addressing the frictional resistance on the obstruction prior to attempting to translate and/or mobilize the obstruction within the body lumen.
US08545524B2	Method and device for interconnection of two tubular organs A method for interconnection of two tubular organs via an opening at one end of an end portion of a first organ and an aperture in a side wall of a second organ. The end portion is initially passed through a first passage of a first element until the end portion projects past an end edge of the element, whereupon the end portion is everted round the end edge. Gripping parts of a second element with a second passage are then inserted in the second organ via the aperture. Finally, the first element with the everted portion of the first organ is inserted in the second passage, whereby the gripping parts are influenced in such a manner that they come into engagement with the inside of an edge portion of the aperture. A device for implementation of the method.
US08545517B2	Systems and methods for improving follicular unit harvesting Tools and methods are provided for dissecting and/or removing biological units, such as hair follicles, from the body surface based on the images both above and below a body surface to reduce potential damage to the removed biological unit. The invention may be used in fully automated systems and also in a hand-held devices and systems. A system may produce a series of three-dimensional images of the body surface indicating follicular unit size, shape, position, and orientation both above and below the skin surface. The images may be utilized by an automated follicular unit harvesting tool, or maybe stored for later use. Imaging techniques include devices that sense light in the visible or infrared spectrums, optical coherence tomography, and ultrahigh frequency ultrasound.
US08545515B2	Curved cannula surgical system A robotic surgical system is configured with rigid, curved cannulas that extend through the same opening into a patient's body. Surgical instruments with passively flexible shafts extend through the curved cannulas. The cannulas are oriented to direct the instruments towards a surgical site. Various port features that support the curved cannulas within the single opening are disclosed. Cannula support fixtures that support the cannulas during insertion into the single opening and mounting to robotic manipulators are disclosed. A teleoperation control system that moves the curved cannulas and their associated instruments in a manner that allows a surgeon to experience intuitive control is disclosed.
US08545512B2	Intraocular lens insertion device An intraocular insertion device capable of safely performing discharge operation of a lens by a simpler construction. The intraocular lens insertion device has a body provided with a lens placement section where the lens is placed and a tube section for inserting the lens into an eye and has a plunger for discharging the lens placed on the lens placement section. The lens placement section has an upper holding member and a lower holding member. The upper holding member has a rib projecting on advancement axis A, to the lower side of the lens placement section. The lower holding member has a U-shaped cross-section and is constituted of a left and right pair of uprising sections and a pressing section uniting the uprising sections at their lower ends.
US08545510B2	Clamping sleeve for clamping a cannulated drill and a guide wire The present invention relates to a clamping sleeve for clamping a cannulated drill and a guide wire for medical purposes, wherein the clamping sleeve can be introduced into the chuck of a drilling machine, comprising: at least one drill contact area which protrudes into the interior of the clamping sleeve in order to clamp the cannulated drill, through which the guide wire runs, when a force acts inwards on the outer side of the clamping sleeve; at least one wire contact area in order to clamp an exposed part of the guide wire which is not enveloped by the cannulated drill when the force acts inwards on the outer side of the clamping sleeve; wherein the at least one wire contact area and the at least one drill contact area lie sequentially in the longitudinal direction of the clamping sleeve.
US08545506B2	Cutting guide for use with an extended articulation orthopaedic implant A cutting guide for removal of bone during arthroplasty. The cutting guide includes a housing having a first portion and a second portion. The first portion includes an attachment mechanism adapted to couple the housing to the bone during arthroplasty and the second portion including a wall defining a continuous path. A blade for cutting the bone is also included, such that the blade slides along the arcuate recess, cutting the bone in a shape matching the continuous path.
US08545503B2	Surgical tool and method A medical device and method. The medical device includes a handle portion, a shank portion, a guide channel and a flexible guide device. The shank portion has a non-linear portion adjacent a distal end. The device is useful in performing medical procedures in the pre-sacral area of a human patient. After inserting the guide device, the shank may be removed leaving the guide device in place and a second medical device can be inserted into the site of interest using the guide device for guidance. The medical procedure can be performed using the second medical device.
US08545502B2	Reciprocating cutting tool The invention relates to a reciprocating cutting tool such as a surgical file system for precisely removing bone and/or other tissue material. The system allows a user to maneuver the system and navigate into hard to access site. The tool may be used to perform a spinal decompression by removing tissue that impinges a spinal nerve.
US08545495B2	Catheter having circular ablation assembly A catheter comprises a catheter body with an ablation assembly at its distal end. The ablation assembly has a preformed generally circular curve generally transverse to the axis of the catheter body, and comprises a flexible tubing that carries a tip electrode at its distal end. In use, the generally circular curve contacts the inner circumference of a tubular region of a patient's heart so that the tip electrode contacts tissue along the inner circumference. After ablating the tissue at this first position, the ablation assembly can be rotated so that the tip electrode contacts tissue at a second position along the inner circumference. After ablating the tissue at the second position, the procedure can be repeated to form a lesion of the desired length.
US08545494B2	Device for testing a neutral electrode The invention relates to a device for testing a neutral electrode (1) for use in electrosurgery, comprising a measuring surface (25) which is formed by a plurality of measuring electrodes (20), whereon the neutral electrode (1) is applied. Each measuring electrode (20) of the measuring surface (25) is connected to a replacement resistance circuit (70) representing at least one layer of the human skin, which is placed in thermal contact with at least one temperature sensor (90). At least one resistance of the replacement-resistance circuit (70) is formed by means of a blind resistance (54).
US08545486B2	Surgical clip applier Surgical clip appliers are provided and include a housing; at least one handle pivotably connected to the housing; a channel assembly extending distally from the housing; a clip carrier disposed within the channel assembly and defining a channel and a plurality of windows therein; and a plurality of clips slidably disposed within the channel of the clip carrier. The surgical clip appliers further include a drive channel reciprocally disposed within at least one of the housing and the channel assembly; a wedge plate reciprocally disposed within the channel assembly; a pusher bar reciprocally positioned within the housing and the channel assembly; and a motion multiplier system having a plurality of linkage members configured to distally move the pusher bar by an incremental amount upon an initial actuation of the handles, and configured to proximally move the pusher bar and the wedge plate subsequent to the initial actuation of the handles.
US08545485B2	Nerve elevator and method of use A nerve elevator tool is disclosed for the recovery of nerve tissue from living or cadaveric donors with minimal or no damage to internal tissues or the external integrity of the body. The elevator tool includes a dissecting head affixed to a shaft with a handle. Advancing the dissecting head through the body with the attached shaft and handle causes the elevator to “strip” tissues and structures from around the nerve and transect or rupture nerve branches with minimal avulsion, which then pass over and around the dissecting head. Once a sufficient section of nerve has been stripped, the second end of the nerve can be transected to completely free the nerve section, which can then be removed.
US08545483B2	Physiological sensors with telemonitor and notification systems Systems and methods are provided which enable communications to be initiated locally relative to an individual's developing physiological condition and remotely as the condition requires. Physiological sensors and associated medical delivery systems can be coupled to a unit wearable by an individual which can provide various audible or visual outputs and one or more manual inputs indicative of the individual's condition. A global positioning unit can be incorporated so that condition information as well as location information can automatically be provided, wirelessly, to a remote monitoring system for follow up as needed.
US08545481B2	Steerable wound drain device The invention relates to a steerable wound drainage device which permits control of the positioning within the body of the device thereby affording the practitioner the ability to re-position the wound drain within the body while avoiding unnecessary trauma to surrounding tissues and organs. In one embodiment, the wound drainage device contains at least one longitudinal duct, at least one internal lumen, and at least one lateral opening communicating therewith, and an internal steering apparatus adapted to controllably position the catheter within the body.
US08545479B2	Male luer connector Certain embodiments of the present invention include a male luer connector having a valve arrangement for keeping a passage that extends through the male luer connector closed when the male luer connector is not attached to a corresponding female luer connector. This passage of the male luer connector may be opened by connecting the male luer connector to a female luer connector. The valve arrangement of the male luer connector may include a movable sealing element arranged around a central fluid conduit. In some embodiments, the male luer connector may include a filter that is permeable to gas, but substantially impermeable to liquid, thus allowing gas to be purged from the male luer connector while substantially preventing liquid from leaking from the connector at least when the male luer connector is not connected to a female luer connector.
US08545474B2	Disposable absorbent article with finger tab without compromising stretch An absorbent article for personal wear includes inner and outer surfaces, an absorbent body disposed therebetween, and front waist, back waist, and crotch regions. The article also includes front and back side panels that are releasably attachable at a seam using an article fastening component and an article fastener landing zone to define a wear configuration of the absorbent article. The article also includes a finger tab attached to one of the front and back side panels, wherein the tab includes a tab fastening component, wherein a front or back side panel includes a tab landing zone, wherein the tab fastening component is fastened to the tab landing zone to form a tab connection when the article is in a wear configuration, and wherein the tab connection has lower peel and shear strengths per unit area than the peel and shear strengths per unit area of the seam.
US08545470B2	Method of packaging an absorbent article and attaching the absorbent article to an undergarment A method of individually packaging an absorbent article and attaching the absorbent article to an undergarment including the steps of providing a tri-folded absorbent article having two end portions and an intermediate portion, providing a pouch containing the tri-folded absorbent article, opening the pouch to thereby expose a garment-facing surface of the intermediate portion of the absorbent article prior to exposing a garment facing surface of either of the end portions of the absorbent article.
US08545467B2	Wound cover connecting device A wound cover connecting device for the sealing connection of a drainage tube and a wound cover covering a wound has a base body for the sealing contact on an outside of the cover. According to the invention, the device comprises at least one penetration element for producing a through-passage in the cover. The device enables a simple, fast, and tight connection between the cover and the tube. In addition, it enables a treatment of the wound that is as uniform and has as large a surface as possible.
US08545466B2	Device for treatment of wounds with reduced pressure Device for treating wounds with reduced pressure. The device comprises a sealing film, which is placed sealingly around the wound to cover the latter, an underpressure source, as well as a tube, which connects a space over the wound and beneath the sealing film to the underpressure source. The interior of the tube comprises a longitudinal first strand made of a hydrophobic material, as well as a second strand, made of an open-pored hydrophilic material, extending longitudinally over at least a part of the length of the tube. The said material strands are enclosed in a tube casing made of a flexible material.
US08545461B2	Automatic body spray system excess liquid removal An embodiment of an apparatus for extracting excess liquid in a human body spray system includes a spray booth defining a booth volume. The spray booth includes a base configured to support the human body and a column having walls extending vertically from the base and at least one vent opening disposed on a bottom half portion of the column on at least one of the walls. The walls form a hollow interior of the column. The apparatus for extracting excess liquid in a human body spray system further includes an extraction fan disposed within the hollow interior adjacent to a top half portion of the column and configured to create a low pressure volume within the hollow interior and draw air flow and at least some of the excess mist from the booth volume through the at least one vent opening.
US08545450B2	Multi-port laparoscopic access device A surgical access device includes a base having two or more ports or apertures that provide for the insertion of surgical instruments. The multi-port insert may be used with a laparoscopic access device. The multi-port insert may also include one or more instrument supports that are attached to the base to fix the position of one or more surgical instruments inserted through the multi-port insert.
US08545448B2	Trocar sleeve A trocar sleeve includes a distal tubular section, a section which connects to the distal tubular section at a proximal side of the distal tubular section and which is widened proximally, and at least one spiral with a circular outer contour, arranged helically on a periphery of the distal tubular section. The distal tubular section includes a rounded polygonal cross section so that maximal degrees of freedom of the applied instruments result.
US08545444B2	System and method for pain-free injections A system for administering pain-free injections includes an electric current source having at least two electrodes attached adjacent an injection site, the electric current source producing a variable numbness pattern and providing a frame of reference for identifying a plurality of sub-areas of the injection site; and a probe applied to the plurality of sub-areas of the injection site for pain-response testing, wherein one or more areas of numbness in the variable numbness pattern are identifiable according to the plurality of sub-areas of the injection site. A fence may be removably applied to the injection site and provide a frame of reference for identifying a plurality of sub-areas of the injection site, and may aid in identifying one or more areas of numbness in the variable numbness pattern. The fence may be removably applied to the injection site via a belt or manual pressure.
US08545441B2	Injector having a displaceable stopper part A disposable injector (4) having a two-chamber system (99), wherein at least one first chamber (105) is part of a piston-cylinder unit (100) that can be accommodated in the disposable injector (4), and wherein the second chamber (255) is part of a chamber (250) which is at least temporarily closed by means of a stopper (257) and inserted into a container adapter (200) detachably mounted on the disposable injector (4), or part of a piston-cylinder unit (254), and wherein the container adapter (200) comprises a connecting tube (242) initially closed by means of a cap (290). To this end, on the side oriented toward the second chamber, the stopper has a recess (271), into which at least one stopper channel (275) connecting the lateral surface (277) of the stopper to the recess (271) opens. After the container has been pushed in or activated, the connecting tube (242) connects the interior of the piston-cylinder unit to the interior of the container or of the piston-cylinder unit via the stopper channel and the tubular channel.
US08545439B2	Feeding apparatus A feeding apparatus includes a food container. The food container includes an open end and a closed end. The food container is provided on a surface thereof with a plurality of apertures and a plurality of protrusions. The food container is made of a resilient material for use with foodstuff.
US08545438B2	Breast pump An electronically controlled breast pump for generating cyclical suction includes a cumulative vacuum pump and a plurality of switches including at least an expression mode cycle time selection switch, a peak vacuum level selection switch, and a stimulation mode switch. A controller coupled to the cumulative vacuum pump controls the apparatus which optionally further includes a four-layer assembly of the various features, an adjustable safety valve, and/or a pump head with a groove traversing top dead center of the pump head.
US08545437B2	Blood sugar level control system A blood sugar level control system for measuring a blood sugar level and administering insulin into a body. The blood sugar level control system includes a blood sugar measuring device having a first wireless data transmitting part to transmit data relating to the blood sugar level; an insulin dispensing device having a wireless data communication unit including a second wireless data transmitting part to transmit data to a second blood sugar measuring device, and a wireless data receiving part to receive data from the first wireless data transmitting part and the second blood sugar measuring device; and an attachment mechanism to couple the insulin dispensing device and the blood sugar measuring device so that the blood sugar measuring device is movable, without separating from the insulin dispensing device at least three specific positions.
US08545432B2	System and methods for controlling retrograde carotid arterial blood flow A retrograde flow system is configured for treating an artery. The system includes an arterial access device adapted to be introduced into an artery and receive blood flow from the artery. A shunt fluidly is connected to the arterial access device, wherein the shunt provides a pathway for blood to flow from the arterial access device to a return site. A flow control assembly is coupled to the shunt and is adapted to regulate blood flow through the shunt between at least a first blood flow state and at least a second blood flow state. A shut-off valve assembly automatically blocks fluid flow through the shunt in response to injection of the fluid into the arterial access device.
US08545431B2	Lumen clearing valve for glaucoma drainage device A glaucoma drainage device has a housing with an open outlet end. A tube is in fluid communication with the housing. An actuator is located in the housing. An actuation arm is located at least partially in the housing and is coupled to the actuator. A tapered arm is rigidly coupled to the actuation arm. A needle head is located opposite the tapered arm. A tapered end of the tapered arm is located at least partially in the tube. When the tapered arm is moved, it can clear an obstruction from the tube. When the needle head is moved, it can disperse aqueous or clear fibers from the drainage location.
US08545430B2	Expandable ocular devices Disclosed herein are systems, devices and methods for treating an ocular disorder in an eye. The ocular device includes a proximal end, a distal end, and an internal lumen forming a flow pathway extending from the proximal end to the distal end; at least one inflow region that communicates with the flow pathway; and an expandable portion having a plurality of interconnected struts forming multiple openings in the device communicating with the flow pathway. The expandable portion has a first cross-sectional shape suitable for insertion into the eye that is generally cylindrical and a second cross-sectional shape that is larger than the first cross-sectional shape. The system also includes a delivery device for inserting the ocular device into an eye including a sheath configured to surround at least a portion of the ocular device; an applier configured to insert into the internal lumen of the ocular device; and an actuator.
US08545428B2	Filtration system for preparation of fluids for medical applications Systems, methods, and devices for preparation of water for various uses including blood treatment are described. In embodiments, fluid is passed either by pump or passively by gravity feed, through various filtration elements from a fluid source to a treatment fluid container. The latter forms a batch that may be used during treatment. The advantage of forming the batch before treatment is that the rate of filtering needn't match the rate of consumption during treatment which provides multiple benefits and liabilities to overcome, as discussed herein. Mechanisms for preparing pure water for infusion or medicaments are described such as elimination of chlorine and colloidal aluminum. Also various control mechanisms to help avoid contamination are describe.
US08545422B2	Moldable decorative material for splints or casts A moldable decorative splint material includes a heat-moldable sheet of splint material adapted to become sufficiently pliable when heated to a first temperature to allow the sheet to be molded into a splint configuration that conforms to an anatomical body part and to become hard when cooled to a second temperature to retain the splint configuration. The splint material includes a plurality of decorative elements integrated with the sheet of splint material. The decorative elements are to be retained by the sheet of splint material when the sheet is heated to the first temperature, molded into a splint configuration, and cooled to the second temperature.
US08545421B2	Manual and spiral massage device A manual and spiral massage device has a retractable rod unit, a bow-shaped frame, and a massage unit. The retractable rod unit has a T-shaped rod including a pair handles and a sleeve. The sleeve is connected with a first end of an inner pipe. A guide rod having a guide block is located in the sleeve. A second end of the inner pipe is inserted in an opening the bow-shaped frame. The massage unit includes an eccentric block, a massage block and the spiral rod. When the retractable rod unit is retracted inward or extended outward, the guide block will spirally turn the guide rod by the elastic force and the restore force of the resilient strips to turn the eccentric block clockwise and counterclockwise. The eccentric axle of the eccentric block drives the second bearing to turn the massage block clockwise and counterclockwise.
US08545419B2	Multi-functional cosmetic device using ultrasonic wave A multi-functional cosmetic device using ultrasonic wave to generate a fine mist of particles that may be ejected from an end of a passage of the nozzle. The cosmetic device is configured to permit ejecting of the fine mist particles even when the device is used upside down so that the user can use the cosmetic device freely at any pose.
US08545418B2	Systems and methods for ablation of occlusions within blood vessels Wire systems for the ablation of occlusions within blood vessels are provided. Systems include one or more wires configured for percutaneous insertion in a blood vessel, the wires configured to ablate an occlusion within the blood vessel. In some embodiments, a wire is gradually tapered near its distal end so that it can be used to pierce occlusions. In some cases, it may be used to dilate existing microchannels within occlusions. In some embodiments, a capture device is inserted towards the occlusion from either the same or opposite side as the tapered wire, and is used to draw the wire through the occlusion.
US08545413B2	Non-contact apparatus for monitoring cardiopulmonary activity signals and method for the same A non-contact apparatus for monitoring cardiopulmonary activity signals comprises a pulse-series generator configured to generate a series of probing pulses and a series of reference pulses, a transmitting antenna configured to emit the probing pulses to a chest portion and a series of scattered pulses generated from the probing pulses by the scattering of the chest portion, a receiving antenna configured to receive the scattered pulses, a mixer including a first input port configured to receive the reference pulses and a second input port electrically connected to the receiving antenna and a signal-processing module configured to generate cardiopulmonary activity signals after the scattered pulses and the reference pulses are processed by the mixer.
US08545411B2	Ultrasound system and method for adaptively performing clutter filtering Embodiments of adaptively performing clutter filtering are disclosed. In one embodiment, by way of non-limiting example, an ultrasound system comprises: an ultrasound data acquisition unit configured to transmit and receive ultrasound signals to and from a target object to thereby output a plurality of ultrasound data for obtaining a color Doppler mode image, wherein the target object includes at least one of a tissue and a blood flow; and a processing unit placed in communication with the ultrasound data acquisition unit and being configured to locate the plurality of ultrasound data on a complex plane, the processing unit being further configured to perform a circle fitting upon the plurality of ultrasound data located on the complex plane and perform a downmixing and a clutter filtering upon the circle-fitted ultrasound data in consideration of speed of the tissue.
US08545409B2	Arrangement and interface for RF ablation system with acoustic feedback A system for ablation with acoustic feedback comprises: a catheter which includes an elongated catheter body; at least one ablation element to ablate a targeted tissue region; and a pulse-echo ultrasonic transducer arranged to emit and receive an acoustic beam along a centroid in a beam direction, at a transducer beam angle of between about 30 degrees and about 60 degrees relative to a distal direction of the longitudinal axis at a location of intersection between the longitudinal axis and the beam direction of the centroid of the acoustic beam of the ultrasonic transducer, wherein the transducer transmits and receives acoustic pulses to provide lesion information in the targeted tissue region; an ablation power subsystem; an ultrasonic transmit and receive subsystem to operate the ultrasonic transducer; a control subsystem to control operation of the ablation power subsystem and the ultrasonic transmit and receive subsystem; and a display.
US08545408B2	Combination catheter for forward and side lesioning with acoustic lesion feedback capability An ablation system comprises a catheter including a pulse-echo ultrasonic transducer disposed in a distal portion and arranged to emit and receive an acoustic beam. The transducer emits and receives acoustic pulses to provide transducer detected information regarding the targeted tissue region being ablated. A rotation mechanism rotates at least the distal portion around a longitudinal axis of the catheter. A control and interface system processes the transducer detected information and provides feedback to a user via a user interface and/or the control and interface system to be used to control ablation. The transducer detected information includes a detected lesion depth along a beam emanation direction. The control and interface system includes a lesion depth correction module which converts the detected lesion depth along the beam direction to a corrected lesion depth in a normal direction which is perpendicular to the tissue surface in contact with the ablation element.
US08545407B2	Method and device for measuring a mean value of visco-elasticity of a region of interest The invention relates to a method for measuring a mean visco-elasticity value for a soft material. The method uses a single probe carrying at least one transducer and includes the steps of: (a) inducing, in a constraint zone, at least one burst of mechanical vibrations in order to generate internal shear waves in the tissue propagating from the constraint zone into the tissue, (b1) measuring, with the transducer, the transient tissue displacements in at least one first measurement zone in the tissue, and wherein the first measurement zone is located away from the constraint zone, and (c) estimating a mean visco-elasticity of the region of the tissue situated between the constraint zone and the first measurement zone from the measured transient tissue displacements of the tissue in the first measurement zone.
US08545404B2	Eyeball tissue characteristic frequency measurement device and non-contact tonometer utilizing the same A non-contact tonometer of the present invention quantitatively measures characteristic vibration of the cornea of an eyeball and measures a true ocular pressure utilizing this vibration, and comprises: an air flow spray unit (200) spraying an air flow (F) to a cornea (C) of an eye (E) to be examined and deforming the cornea; a cornea deformation amount measurement unit (300) measuring deformation of the cornea caused by the air flow spray unit along with elapsed time from the start of the air flow spray; a Fourier analysis unit (401) performing Fourier analysis on a relationship between a deformation amount of the cornea obtained by a cornea deformation detection unit and the elapsed time; an eyeball tissue characteristic frequency operation unit (402) obtaining an characteristic frequency of each constituent tissue of the eyeball based on a Fourier analysis result obtained by the Fourier analysis unit; and an ocular pressure operation unit (403) calculating an ocular pressure based on the characteristic frequency of the cornea obtained by the eyeball tissue characteristic frequency operation unit.
US08545400B2	Endoscope An endoscope of the present invention includes an insertion section including a distal end portion, an objective lens placed in the distal end portion, an illumination lens which is placed in the distal end portion adjacently to the objective lens and emits illumination light from a light source, and a wall portion which is placed between the objective lens and the illumination lens, and shields the illumination light, and thereby, secures a sufficient illumination range for an image pickup range with a wide field of view, can obtain a favorable endoscope image and can reduce the diameter.
US08545399B2	Medical instrument A medical instrument is provided with: an illumination section radiating excitation light for exciting a fluorescent substance given to a subject, to the subject; an image pickup section photoelectrically converting reflected light from the subject to which the excitation light is radiated, to pick up an image of the subject; a reading section holding pixel signals obtained by the photoelectrical conversion and capable of reading the pixel signals non-destructively while changing amplification factors of the held pixel signals by a predetermined unit of pixels; and an image processing section determining an arithmetic mean of the pixel signals read with different amplification factors by the reading section to generate an image. The medical instrument improves visibility of each fluorescent area without occurrence of position displacement even in the case where multiple fluorescent areas with a relatively large brightness/darkness difference exist within one screen.
US08545398B2	In-vivo image acquiring apparatus, receiving apparatus and in-vivo image acquiring system An in-vivo image acquiring system includes a capsule endoscope which is introduced into the inside of a subject to acquire an in-vivo image of the subject and a receiving apparatus for receiving the in-vivo images of the subject from the capsule endoscope through receiving antennas. The capsule endoscope transmits the in-vivo images of the subject taken successively at a time interval corresponding to function or feature of the capsule endoscope. The receiving apparatus calculates a time interval of the in-vivo images received successively from the capsule endoscope and identifies the in-vivo images depending on the function or feature of the capsule endoscope based on a calculated time interval.
US08545397B2	Endoscope shape analysis apparatus An endoscope shape analysis apparatus includes a coordinates obtaining portion for obtaining coordinate values of an insertion portion; a storage portion for storing the coordinate values; a straight line setting portion for setting a first straight line A and a second straight line B, based on the coordinate values; a coordinate transformation portion for transforming coordinates of a previous second straight line B1, based on a positional relationship between a previous first straight line A1 and the first straight line A, to calculate a third straight line B2; a determination portion for determining whether there is an error in a position display from a positional relationship between the first straight line A, the second straight line B, and the third straight line B2; and a correction portion for correcting the second straight line B.
US08545393B2	Inflatable penile implant A method of providing a user with a body implantable penile prosthetic includes providing a pump attachable to a pressure reservoir and a penile implant; pressurizing liquid in the pressure reservoir; configuring the pressure reservoir to release the pressurized liquid from the pressure reservoir to the penile implant at a first pressure for inflating the penile implant to an erect state; and pumping the pressurized liquid from the penile implant to the pressure reservoir and pressurizing the pressurized liquid to a second pressure greater than the first pressure.
US08545391B2	Penile prosthesis implantation device A penile prosthesis implantation device comprises a barrel having a bore, an obturator and a needle clamp. The obturator has a longitudinal axis, a first end and a second end. The second end of the obturator is adapted for slidable insertion into the bore of the barrel. The needle clamp is coupled to the second end of the obturator and comprises first and second pinching surfaces that are separated by a gap.
US08545387B2	Apparatus and method for minimally invasive implantation of heart assist device A method and related apparatus for the minimally invasive implantation about a heart of at least a deployable device such as a heart assist device or cardiac compression device. The method comprises the steps of performing a left thoracotomy or subxiphoid incision; obtaining access to the pericardial sac; making a generally linear incision in the pericardial sac; positioning an assembly having an insertion aperture member with an upper ring and a lower ring or flange and insertion tube having therein a deployable device. The apparatus of the present invention includes an insertion aperture member having an upper ring and a lower ring or flange; and an insertion tube having therein a deployable device adapted to be deployed from the insertion tube inside the pericardial sac via a generally linear incision.
US08545386B2	Surgical slings The invention relates generally to surgical implants, and in various embodiments to surgical implants configured for promoting growth of collagenous tissue at an anatomical site.
US08545375B2	Top lift carrier and method of manufacture therefor A carrier and a method for making a carrier with handles between rows of containers in both two-wide and three-wide configurations, and with the handle portion and container holding portion formed from different sheets connected together.
US08545374B2	System as well as a machining device, a chuck, a jaw connecting element, a jaw exchanging device and a method A system comprises a machining device which comprises at least one chuck and at least one jaw detachably connected to said chuck, as well as a jaw exchanging device cooperating with said machining device. The chuck is provided with at least one locking element which can be moved in a locking direction and in an opposite direction, from a jaw releasing position to a jaw locking position, and vice versa, by means of the jaw exchanging device. The jaw exchanging device is provided with moving means for moving the jaw with respect to the chuck in said releasing position. The chuck is provided with a rotatable operating pin extending transversely to the locking direction, by means of which the locking element can be moved from the releasing position to the locking position and vice versa. The jaw exchanging device is provided with a connecting element to be connected to the operating pin, by means of which connecting element the operating pin can be rotated.
US08545371B2	Rehabilitation exercising equipment that can extend a user's arms A rehabilitation exercising equipment includes a main frame, a first geared member rotatably mounted on the main frame, a second geared member rotatably mounted on the main frame, two handlebars secured on the first geared member and the second geared member respectively, a connecting mechanism mounted between the first geared member and the second geared member to connect the first geared member and the second geared member, and a transmission mechanism mounted between the main frame and the second geared member. Thus, a user's two hands can hold the handlebars to pivot the handlebars in two opposite directions by connection of the connecting mechanism so as to achieve an exercising or rehabilitating function.
US08545370B2	Rehabilitation exercising equipment that can extend a user's arms Rehabilitation exercising equipment includes a main frame, a first geared member rotatably mounted on the main frame, a second geared member rotatably mounted on the main frame, a connecting mechanism mounted between the first geared member and the second geared member to connect the first geared member and the second geared member so that the first geared member and the second geared member are movable in concert with each other, and two handlebars secured on the first geared member and the second geared member to rotate in concert with the first geared member and the second geared member respectively. Thus, a user's two hands can hold the handlebars to pivot the two handlebars in two opposite directions by connection of the connecting mechanism so as to achieve an exercising or rehabilitating function.
US08545369B2	Methods, systems, and computer program products for providing remote participation in multi-media events Implementing remote participation in events is provided. The implementation includes providing a view of an instance of an application on endpoint systems in response to a common option received from users of the endpoint systems of the application, receiving a role from each of the users that include an active participant role and a coach role, and receiving performance data from the endpoint systems. The implementation also includes populating the view with virtual representations of the users of each of the endpoint systems having the active participant role. The populating includes positioning the virtual representations at various locations in the view. The various locations are indicative of the performance data and the view represents an event selected as the common option, which includes a simulated exercise course.
US08545367B2	Hybrid system A hybrid system includes a hybrid module that is located between an engine and a transmission. The hybrid system includes an energy storage system for storing energy from and supplying energy to the hybrid module. An inverter transfers power between the energy storage system and the hybrid module. The hybrid system also includes a cooling system, a DC-DC converter, and a high voltage tap. The hybrid module is designed to recover energy, such as during braking, as well as power the vehicle. The hybrid module includes an electrical machine (eMachine) along with electrical and mechanical pumps for circulating fluid. A clutch provides the sole operative connection between the engine and the eMachine. The hybrid system further incorporates a power take off (PTO) unit that is configured to be powered by the engine and/or the eMachine.
US08545364B2	Gear set arrangement of a planetary transmission A gear set arrangement for a planetary transmission comprising at least first and second simple planetary gear sets, each having sun and ring gears and a carrier supporting planetary gears. The gear sets are coaxially nested with the first gear set being radially within the sun gear of the second gear set in a common radial plane or radial planes which are only slightly axially offset. The ring gear of the inner first gear set and the sun gear of the outer second gear set, and the carriers of the two gear sets, are coupled in a fixed manner. To avoid forced movement of the gears, only one of the sun gear, the ring gear or the carrier, of each of the first and the second gear sets is radially supported substantially free of radial play on a centrally disposed transmission shaft or with respect to a centered supported component.
US08545358B2	Gear transmission A gear transmission is provided with an internal gear and an external gear that eccentrically rotates relative to the internal gear while meshing with internal gear. The internal gear includes first recesses formed on an inner circumferential surface of a case so as to be side-by-side in a circumferential direction, and inner pins inserted into the first recesses. A second recess is formed on the inner circumferential surface of the case within a distance from the center of a first recess along the circumferential direction that equals the tooth pitch of the external gear. Lubricant is retained in the second recess.
US08545357B2	Gear transmission An external gear has a number of teeth differing from a number of teeth of an internal gear, and is maintaining in a meshing state with the internal gear. A center through hole and an offset through hole are formed in the external gear. The center through hole is formed at the center of the external gear, whereas the offset through hole is formed at a position offset from the center of the external gear. Column-shaped member of a carrier passes through the offset through hole. A pair of supporting members of the carrier respectively supports each end of the column-shaped member. A pair of grooves is formed on a surface of a shaft of a crank member at positions between which an eccentric rotation member of the crank member is interleaved. First rolling elements and first outer races are arranged between the supporting members and the grooves. The shaft of the crank member is supported so as to be capable of rotating with respect to the carrier and incapable of moving in its axial direction.
US08545349B1	Broadhead arrowhead having deployable blades A rear deploying mechanical broadhead arrowhead is provided and includes a broadhead body having a body opening and a body length, wherein the broadhead body defines a body cavity and includes a plurality of slots, wherein each of the plurality of slots traverses a portion of the body length and is disposed such that each of the plurality of slots is on an opposing side of the broadhead body. A blade system is also provided and includes minor blades and deployable blades, wherein the deployable blades are movable relative to the minor blades. The blade system is movably disposed within the body cavity such that the plurality of minor blades and plurality of deployable blades are protruding from the plurality of slots. A broadhead base having a base head securely associated with the body opening to be partially disposed within the body cavity to enclose the body cavity.
US08545348B2	Golf-course guide A golf-course guide is provided with true to scale information maps of the individual holes for orientation about the quirks and distances of the respective hole. Detailed golf-course features which serve at least as an orientation aid for visual position determination are indicated by way of each information map of the respective hole which is shown to scale. A measurement aid is provided which includes a distance scale which corresponds to the scale of the information map, in order for it to be possible to determine the distances which are relevant for the player. A golf-course guide of this type can be handled simply and produced inexpensively.
US08545347B2	Golf ball with oriented particles A golf ball with a layer of composite material applied to at least one surface of one layer of the ball. The composite material includes a plurality of particles. The particles are shaped to enable specific orientations. A percentage of the particles in the composite material achieve a specific orientation. A portion of at least one of the particles extends from the composite material layer and into an adjacent, surrounding layer. The particles may have a tetrapod shape. The composite layer may be applied as a thin film coating, such as in a primer layer.
US08545341B2	Eight-directional controlled dynamic plate based on one-point An eight-directional controlled dynamic plate based on one-point allows a central portion of a forward side of the dynamic plate with feet of the golfer being positioned thereon to be connected in one-point to the swing plate body, and the dynamic plate to be inclined in eight directions including a forward, a rearward, a leftward, and a rightward direction and four edge directions, so that the dynamic plate is to be positioned corresponding to an inclination surface and an inclination angle of actual outdoor golf course.
US08545339B1	Golf grip guide The present invention provides a golf grip training aid that includes a golf grip training aid that includes a glove and a golf club handle grip or grip cover, the handle grip or grip cover having a plurality of discrete co-operating contact zones marked thereon spaced apart therealong in locations to define a good grip position and adapted to be co-operatively used with corresponding discrete co-operating contact zones marked on the glove whereby the user may discern when their hand in the glove is in the required good grip position on the handle grip or grip cover by mutual covering of the co-operating contact zones on the glove with the co-operating contact zones on the handle grip or grip cover.
US08545338B2	Automatic golf ball supply device The present invention comprises: a frame; an ascending and descending vertical carrier; a motor; a first rod for performing a forwards rotation or backwards rotation movement; a second rod linked in movement to the other end of the first rod; a separating type of pressed-member which separates from the ascending and descending vertical carrier when the ascending and descending vertical carrier is ascending, and which collides with and is pressed by a pushing plate formed in the other side surface of the ascending and descending vertical carrier when the ascending and descending vertical carrier is descending; a rotational force transmission means for converting the pressing force of the pressed-member into a rotational force; and a golf ball guide member means for nudging the golf ball and settling it on a tee member of the ascending and descending vertical carrier when the vertical carrier has descended.
US08545337B2	Fixed uniform-motion universal joint A fixed type constant velocity universal joint of an eight-ball undercut-free type has improved torque capacity at high operating angle while ensuring durability at low operating angle. Centers of a track groove (32) of an outer joint member and a track groove (35) of an inner joint member are respectively separated from a center plane (P) toward axially different sides, and are offset away from a joint center axis (X) to a radially opposite side relative to grooves (35). When Rt represents a distance between a center of a ball (37) and the center of groove (32), and F represents an axial distance between plane (P) and the center of groove (32), a ratio R1 between F and Rt is 0.061≦R1≦0.087. When fr represents a radial offset amount as a distance between axis (X) and the center of groove (32), a ratio R3 between fr and Rt is 0.07≦R3≦0.19.
US08545324B2	Communication game device A communication game device which is disclosed can communicate with another game device, memorize the information about a communication partner at the time of the communication, and offer the communication game device which can process information for the succeeding game to be reflected in the contents of a game or the simulation. The communication game device has a processing section, a program storage part which memorizes a control program, an image storage section which memorizes character pictures matched with picture IDs, and controlling elements which can be operated by a game player. When the player's game device receives parameters from another communication game device, the parameters are stored or the data is renewed. If a parameter containing a body ID and the same body ID as arbitrary data is not stored, the arbitrary data in the parameter is memorized. If the parameter has been memorized, it is updated.
US08545322B2	Gaming machine with proximity sensing touchless display A device for providing a proximity sensing touchless display to a gaming machine is provided. The device includes a processor, a display coupled to the processor, and a touchless input interface coupled to the processor and being implemented by the display for receiving input from the player. The input interface employs proximity sensing technology, such as but not limited to proximity button activation. For example, the display can be operable to sense a player's approaching finger entering an electrical field (e.g., corresponding to one or more electrodes) such that a particular button or function on the interface can be activated without the player's finger having to ever physically contact a button, push pad, keypad, touch screen, and/or the like.
US08545315B2	Gaming system and method A player accesses a game terminal, which is networked to other game terminals configured to play standard games and game-in-games. The player initiates a standard game (e.g., lottery slot) on the game terminal. The game terminal receives a game initiation request for the standard game and starts a timer. Prior to expiration of the timer, the player may perform a predefined action (e.g., pressing a spin button) indicating that the player wishes to play a game-in-game (e.g., a “community prize” game). If the timer expires without the player performing the predefined action, (s)he is deemed ineligible to win an award associated with the game-in-game. However, in response to player performing the predefined action prior to the timer's expiration, the player is deemed eligible to win an award associated with the game-in-game, and the player participates in both the game and the game-in-game.
US08545314B2	Method and apparatus for awarding individual or group point multiplication In use, the player would insert his or her player card at the EGM 10. The system checks to see if any multiplier currently applies to the machine and player. The multiplier is available as a token and can communicate to the guest via display on the EGM. The multiplier would be displayed using a conditional message feature of the display. Session points would accumulate at the “multiplied” rate and are displayed as such on the EGM display. Alternately, an assurance message is available to be displayed frequently that shows the current multiplier. When the player removes his or her card, the session is posted to the patron management system. Casino personal can then review the session detail by accession the history of the player at a workstation capable of querying the player tracking system. The session multiplier and points earned by the multiplier are listed within the record.
US08545313B2	Gaming system, gaming device and method for providing a multiple player, multiple game bonusing environment A gaming system and method for exchanging one or more triggered individual bonus games for one or more current plays of a community game or one or more future plays of a community game. If an individual bonus game is triggered in association with an individual gaming device, the gaming system enables the player to: (i) play the triggered individual bonus game, (ii) skip the individual bonus game and play or participate in a community or group game, or (iii) skip the individual bonus game and save an entry to play or participate in a future community or group game. In these embodiments, the gaming system determines one or more features or attributes of the available community game (which the player may play or defer play of) based, at least in part, on which of a plurality of different individual bonus games are triggered.
US08545301B2	Remote card game with duplicate hands Duplicate hands are dealt in a remote game of poker or other card game of chance. Simulated cards or game pieces are dealt to players with the order of suits changed for each player. A map is maintained in a computer memory between a reference set of indices corresponding to card suits, and differently-ordered sets of playing suits for dealing in the game. A reference game is maintained at a server computer to track game status according to the reference set of indices. Game play is translated between the reference game and individual playing suits so that players are unaware of the order of suits used for other players.
US08545300B2	System and method of tracking and displaying outcomes of a live craps game A system and method for recording and displaying craps game data is disclosed. A display positioned proximate to a craps table displays craps game data which can be manually input or acquired automatically. Manually inputting craps game data is facilitated by a remote control device in communication with the display. A scanner, camera or other image capturing means can be used to acquire dice roll outcomes which are then automatically transmitted to the display. Various displayed craps game data, including a roll history and a clock, allow players to observe whether a craps table is hot or cold. System memory permits best rolls of the day, week, month, year or all time to be displayed as well.
US08545298B2	Roof ridge wind turbine Disclosed are systems and method that generally relate to the capture of wind energy by small wind turbines mounted on buildings with gabled roofs. Wind energy harnessing system for gabled roof buildings having a roof ridge including a low silhouette visually appealing enclosure mounted along the roof ridge of a building and extending down both sides of the roof forming the ridge. The enclosure includes airflow guides defined by columns extending down a length of both sides of the building roof forming sidewalls and a roof formed of pivoting louvers above the columns. A paddle-wheel type wind turbine consists of a multiple-bladed cylindrical shaft that contacts the wind and provides rotational work mounted within the enclosure and a generator connected to the wind turbine for converting the rotational work from the wind turbine to electrical energy. The enclosure for the wind turbine functions to capture wind and directs the airflow via the airflow guides before it reaches the ridge.
US08545295B2	Coin processing systems, methods and devices Systems, methods and devices for processing coins are presented herein. A coin processing system is disclosed which includes a housing with a coin input area for receiving a batch of coins, a controller with a communication interface operatively attached to the housing, and a coin processing unit for counting, discriminating, and/or valuing coins received from the coin input area. The coin processing system also includes a mobile coin receptacle removably disposed within the housing and configured to receive coins from the coin processing unit. The mobile coin receptacle is configured to wirelessly communicate information to the communication interface of the controller. The mobile coin receptacle can include one or more electrical contacts that mate with one or more electrical contacts on the housing to wirelessly communicate the information.
US08545289B2	Distance monitoring device A distance monitoring device is provided. The device is suitable for a chemical mechanical polishing (CMP) apparatus. A polishing head of the CMP apparatus includes a frame and a membrane. The membrane is mounted on the frame, and a plurality of air bags is formed by the membrane and the frame in the polishing head. The distance monitoring device includes a plurality of distance detectors disposed on the frame corresponding to the air bags respectively to set a location of each of the distance detectors on the frame as a reference point, wherein each of the distance detectors is configured to measure a distance between each of the reference points and the membrane.
US08545288B1	Support bra device A reversible one-piece support bra device. The support bra device features a front section for covering and supporting a user's breasts. The front section has a first end, a second end, a top edge, and a bottom edge. The first end and second end are for positioning under a user's arms. A back section connected to front section. Together the back second and front section wrap around a portion of a user's torso around the breasts. A strap extends upwardly from the top edge of the front section near the second end. The strap extends to the back section and is for positioning over a user's shoulder.
US08545285B2	Toy with built-in school pencil case “TOY WITH BUILT-IN SCHOOL PENCIL CASE” refers to the technical field of toys and school supplies, more specifically to a toy with built-in school pencil case (1). It is a toy with two utilities, with the characteristics and shape of a miniature vehicle (car or another), equipped with a practical case, that fits to a compartment located in its own interior. The car or another toy could be used for playing, as well as it could be brought to school, where the school pencil case (pencils, erasers, scissors, etc . . . ) will be drawn from its interior.
US08545283B2	Interactive doll or stuffed animal A toy has a body in the form of a doll or a living being, an audio output to reproduce audio effects, a memory to provide audio data, a controller to control the reproduction of different audio effects based on the reading of the audio data, and a sensor for generating detection signals correlated with the proximity of an object to the toy. The controller is designed in such a way that a selection of the reproduced audio effects depends on an evaluation of the detection signals and of signals generated by a provided interface device that is connected through devices in the play accessories being fed to that controller, and/or being made available for access.
US08545280B1	Spray shield for surface-piercing gearcase A marine drive has a lower drive unit including a gearcase with a vertical strut having a lower horizontal torpedo with an aft propeller. An anti-ventilation plate on the strut is spaced above the torpedo. A spray shield plate on the strut is spaced above the torpedo and below the anti-ventilation plate.
US08545278B2	Method and apparatus for operation of a marine vessel hybrid propulsion system A method for operation of a hybrid propulsion system for a marine vessel, including at least one electric motor and at least one internal combustion engine as drive units, is disclosed. Depending on the requirement, for example the vessel speed, the drive units individually or jointly drive at least one propulsion unit, for example a propeller, the power outputs of the drive units to the at least one propulsion unit controlled by a control device as a function of a set value, for example a set value for the propeller rotation speed or the vessel speed, and an operating mode such that the sum of these power outputs results in a total power being output to the at least one propulsion unit, with this total power output being split between the power outputs of the individual drive units as a function of the set value and the operating mode.
US08545276B2	Multi-pin breakaway connector with fixed and retractable pins A breakaway connector assembly which has first connector having a first housing, a plurality of retractable pins attached to the housing, and a plurality of fixed pins attached to the housing and circumscribing the plurality of retractable pins. A second connector is matable to the first connector, the second connector having a plurality of contacts adapted to engage the plurality of fixed pins.
US08545274B2	Filtering assembly and modular jack using same A magnetic jack assembly includes a housing, circuit boards, shields and various filtering components. Multiple aspects of the assembly enhance manufacturability and facilitate automated manufacturing.
US08545266B2	Plug connections on radar sensors and method for their production Plug connections on radar sensors include plug pins which are inserted into plastic. The plastic that surrounds the plug pins is at least partially provided with a granulate that absorbs radar waves, such that the electrical impedance of the plastic has a high value in low-frequency range, and the plastic comprises a characteristic which absorbs radar waves in a region of higher-frequency radar waves. The plug pins are surrounded by a thin layer of plastic without radar-absorbent granulate, and a remainder of an area surrounding the plug pins includes the plastic with the granulate which absorbs radar waves.
US08545260B2	Base and electronic apparatus using the same A base is capable of containing a data cable, the data cable having a first plug, a second plug and a transmitting wire connecting the first plug and the second plug. The base includes a housing defining an opening; and a receiving member and a winding member positioned on the inner surface of the housing. The first plug is capable of protruding out of the housing via the opening, the transmitting wire is capable of being wound around the winding member, and the second plug is capable of being received in the receiving member.
US08545258B1	Structure for removable processor socket A socket has top side pins that may form electrical connections to a central processing unit chip, and a bottom side ball grid array of discrete, electrically-conductive metal surfaces. Differently-keyed setoff apertures are formed through the socket that when disposed about corresponding standoffs projecting upward from a planar circuit board align the socket ball grid array surfaces with grid array pad connections on the circuit board. Retaining screws passing through the socket setoff apertures, when tightened into the planar board standoffs, bring a heat-sink downward with compressive force against the socket top side. The socket responsively brings the ball grid array into compressive electrical contact connections with the grid array pad connections on the circuit board, and also compresses a against the planar board. The resilient ring may thereby form a seal about the compressively-connected ball grid array and circuit board pads.
US08545257B2	Integrated banding connector Integrated electrical connectors (14) and electrical cable assemblies (10) constructed therewith are provided. Connectors (14) permit termination of braided electrical cables (12) without the use of backshell adapters and without requiring undue stretching of the braided sheath (84) over a relatively large cable sheath termination nipple (46) which could lead to undesirable EMI. Connectors (14) comprise a plurality of hinged petals (40) that are shiftable between an open position, which permits access to the connector insert (18) carried by the connector (14) and a closed position in which the petals (40) cooperate to define an appropriately-sized cable sheath termination nipple (46).
US08545252B2	Plug connector having a releasing mechanism A plug connector (100) configured for latching with a receptacle having a latching tab includes a housing (1) defining a top wall (14) and two opposite sidewalls (13), and a releasing mechanism (2) assembled to the housing. The releasing mechanism includes a pair of sliders (21) movably attached to the sidewalls, and an extension spring (25) attached to the top wall. The spring has two free ends (250) respectively connected to the sliders. Each of the sliders includes a narrowed and protruded actuating end (211) adapted for releasing the latching tab of the receptacle from the plug connector when the slider moves from a first position to a second position. The movement of the sliders elongates the spring into an extended state at the second position. The extended spring tends to restore the sliders to the first position.
US08545251B2	Locking electrical socket A locking electrical plug is disclosed having a rigid tubular housing which rotates axially around a partially enclosed cylindrical socket face. As the tubular housing rotates, internally projecting cam engages clevis pins on the socket face, which pins lock through apertures of male electrical prongs detachably inserted into jacks on the socket face. The clevis pins are disengaged from the electrical prongs as the tubular body is rotated backward, the clevis pins biased back into an open position by resilient springs. Certain embodiments of the present invention recite electrical outlet embodiments comprising a plurality of socket faces. The locking electrical socket securely retains the male end of a US 120 volt electrical plug, but may be embodied to retain the male end of a US 220 volt electrical plug or electrical plugs of various international standards.
US08545249B2	Locking assembly and communication apparatus using same A locking assembly used to lock an electronic device defining at least one latching hole in a communication apparatus includes a housing including a mounting board and a front board, a latching member fixed to the mounting board, a button member mounted between the front board and the latching member, an urging member pivotably connected to the housing and an elastic member elastically connected between the housing and the urging member. The latching member includes at least one latching portion to engage with the at least one latching hole. When the button member moves relative to the housing and compels the at least one latching portion to disengage with the at least one latching hole, the urging member is enabled to push the electronic device to move out from the communication apparatus via elastic deformation energy of the elastic member.
US08545248B2	System to control fluid flow based on a leak detected by a sensor A system including a communication interface to communicatively couple to a sensor cartridge, a fluidic subsystem to exchange a reagent solution with the sensor cartridge, and a computational circuitry communicatively coupled to the communication interface and the fluidic subsystem. The computation circuitry is to monitor a sensor signal of a sensor of the sensor cartridge, detect a leak based on the sensor signal, and control fluid flow of the fluidic subsystem in response to detecting.
US08545245B2	Electrical busway plug-in unit with improved restraint mechanism An electrical busway plug-in unit includes a pair of restraint mechanisms extending through the housing of the plug-in unit for mechanically attaching the plug-in unit to the busway. Each restraint mechanism includes a rotatable shaft extending through the front wall of the housing, and a knob attached to the front end of the shaft, on the exterior side of the front wall of the housing, for manually rotating the shaft. A mechanical connector projects rearwardly from the rear wall of the housing and extends forwardly into the interior of the housing where the connector is coupled to the shaft so that rotational movement of the shaft in opposite directions moves the connector into and out of latching engagement with the busway.
US08545243B2	Lock structure of plug of cable The present invention provides a lock structure of plug of cable including a main body and a key. The main body has a locking area, an elastic area with an elastic element, and a lower room which is able to receive a plug of cable. The elastic element tends to stay at a first position. When the key is not inserted into the locking area, the elastic element is at the first position, and a latch of the plug of the cable is unable to be compressed due to the fixation by the elastic element. When the key is inserted into the locking area and is rotated, the elastic element is pushed to a second position, and the latch is able to be compressed. Thereby, the lock structure of plug of cable can be used to control the availability of the plug for a jack.
US08545222B2	Method of dental implant restoration The invention provides a method for dental restoration including direct modification of an abutment in the oral environment to obtain the ideal shape, contour, and margin placement. The method is featured with directly measuring the shortest distance X1 between a location L1 on the surface of the abutment and the surface of a surrounding object, and increasing the shortest distance X1 until it is not less than a predetermined value. The invention exhibits numerous merits such as simplified procedure, cost-effectiveness, reduction of laboratory adjustment, reduction of chair time, and reduction of office visits.
US08545219B2	Outie tool for removal of a plastic tooth positioning appliance or aligner (invisible braces) from teeth of a patient An apparatus and method for the efficient, safe, and hygienic removing of removable tooth positioning appliances such as aligners or other dental appliances from the teeth of a patient. A straight rigid barrel has a lever appendage on the proximal end for fully engaging and removing a lower aligner and a hook appendage on the distal end for fully engaging and removing an upper aligner.
US08545218B2	Label manufacturing method and label manufacturing apparatus A label manufacturing apparatus includes a thermal head and a device for transporting a heat sensitive adhesive sheet. The control device operates the head in synchronization with timing of transporting of the sheet to activate the adhesive, determines if heating based on a last row of a heating pattern is completed before a trailing end of the sheet reaches a set position contacting the head, controls driving of the transporting device so that when it is determined that the heating based on the heating pattern last row is completed, the sheet is transported until the trailing end passes through the set position, and controls driving of the head so that when it is determined that the heating based on the last row of the heating pattern is completed, the heating based on the last row of the heating pattern is repeated until the trailing end passes through the set position.
US08545214B2	Combustion blower control for modulating furnace A furnace includes a combustion blower and one or more pressure switches. In some cases, the one or more pressure switches may be used to calculate one or more operating points for the combustion blower. Additional operating points may be calculated by interpolation and/or extrapolation, as appropriate. The furnace may temporarily alter these operating points as necessary to keep the furnace safely operating in response to minor and/or transient changes in the operating conditions of the furnace.
US08545213B2	Reformer and method of operating the reformer A method of combustion and a reformer. The method includes combusting a fuel in a combustion region of an up-fired or down-fired reformer and forming non-uniform injection properties with a wall-bound burner. The combusting is performed in a combustion region by burners, wherein at least one of the burners is the wall-bound burner forming the non-uniform injection properties. The non-uniform injection properties generate a heat profile providing a first heat density proximal to a wall and a second heat density distal from the wall, the second heat density being greater than the first heat density. The non-uniform injection properties are formed by injection properties selected from an angle of one or more injectors, a flow rate of one or more injectors, an amount and/or location of oxidant injectors, an amount and/or location of fuel injectors, and combinations thereof.
US08545210B2	Method and device for the molding of wood fiber board The invention relates to a method and device with which it is possible to arrange complicated shapes with considerable differences in height in wood fiber board, and in particular but not exclusively so called MDF (Medium Density Fiberboard). The deformation of the wood fiber board which can be achieved is known in the art as extrusion, wherein a considerable plastic deformation takes place accompanied by flow and stretch of the material.
US08545207B2	Roller type electrostatic spinning apparatus A roller type electrostatic spinning apparatus is disclosed, which includes an electrostatic spinning solution impregnation mechanism having a tank for containing an electrostatic spinning solution and a sizing roller rolled in the tank, a chain emitting electrode touching the sizing roller to coat the electrostatic spinning solution onto the chain emitting electrode, a collecting electrode, and a high-voltage power supply connected to the chain emitting electrode and the collecting electrodes respectively.
US08545203B2	Mould system for manufacturing a container A mould system for manufacturing a container which includes a movable mould half and a stationary mould half which are positioned opposite to each other, wherein the movable mould half includes a core plate provided with a core, a plate-like seal ring that is movable relative to the core, a seal surface which surrounds the core, and a collar ring that is movable relative to the core and the stationary mould half includes a mould plate provided with a mould cavity and a seal surface, wherein in the mould system, a plate-like insert is connected to the seal surface of the seal ring, the insert including a recess which is in contact with a front edge of the seal surface, so that it is in flow communication with molten plastic material flowing from the direction of the collar ring.
US08545194B2	Battery operated solar charged pump kit utilizing an inline submersible pump A rechargeable battery operated solar pump kit is provided including a solar panel to provide solar power via an electrical terminal, an inline submersible pump and a control box containing a pipe fitting, a rechargeable battery, an electrical fitting and an on/off switch. The inline submersible pump passes through a rain barrel, having a hose to discharge rainwater from the rain barrel, and a power cord, which is coupled to the rechargeable battery. The pipe fitting couples to the hose to receive the pumped rainwater and to a garden hose to provide the pumped rainwater. The electrical fitting couples the rechargeable battery to the electrical terminal of the solar panel and receives solar power to recharge the rechargeable battery. The on/off switch couples the rechargeable battery and the power cord to turn the inline submersible pump on/off to pump the rainwater.
US08545192B2	Diesel pump with cylinder and outlet joint arrangement A diesel pump having enhanced durability in a high pressure environment, capable of being produced at high productivity, and at low cost. The diesel pump is provided with a cylinder formed in a pump housing, a plunger reciprocatably provided in the cylinder, and a drive mechanism for driving the plunger. The cylinder is a separate part from the pump housing and is mounted in the pump housing. The cylinder consists of sulfur-less alloy steel, is a tubular part and may be press-fitted in the pump housing. The front end of an outlet joint reaches the cylinder, and a fuel discharge route directly connects to the outlet joint from the cylinder without passing through the pump housing.
US08545191B2	Water pump for vehicle A water pump for a vehicle includes a power transmitting member, a driven shaft rotated independently from the power transmitting member, an impeller, a biasing member for pressing an inner circumferential surface of the power transmitting member and for rotating in order to transmit a rotation of the power transmitting member to the driven shaft when the biasing member contacts the inner circumferential surface, and a control member for allowing the power transmitting member and the biasing member to come in contact with each other or to come out of contact from each other and for controlling a contacting state between the power transmitting member and the biasing member.
US08545190B2	Valve with shuttle for use in a flow management system A valve with a shuttle for use in a flow management system is capable of bypassing a backflow.
US08545187B2	Systems and methods for protecting a wind turbine in high wind conditions Systems for protecting a wind turbine in high wind conditions are disclosed. A shrouded turbine may have an ejector shroud disposed adjacent and downstream of a turbine shroud. In one version, the ejector shroud can move to surround the turbine shroud. In another version, the turbine can be pivoted on a support tower to cover the intake end of the turbine and rotate the turbine about an axis at a right angle to the tower axis. In another version, the turbine is supported by a telescoping tower which may be retracted to lower the turbine in high winds. In another version, the tower sections may be connected by a pivotable connection and supported by guy wire(s) which may be lengthened to lower the upper tower section pivotally.
US08545179B2	Structural monitoring of wind turbine with fibre bragg grating sensors in each blade A system for the structural monitoring of blades 1 on a wind turbine. Each blade 1 has respective optical fiber bragg grating sensors 5. The system has a number of input connectors, which connect to the strain sensors 5 of respective blades 1. A single output connector connects to a data processing device 3 which processes signals from the strain sensors 5. The input connectors each have a signal path to the output connector that is different in length to the signal path from the other input connectors, such that signals from a given blade 1 can be identified at the data processing device 3 by the time of arrival of the signals. The system has the advantage that the each of the blades 1, including the sensors attached to it or embedded within it can be identical and therefore interchangeable.
US08545178B2	Controlled propeller pitch lock actuation system A variable pitch propulsor system with a propeller pitchlock system having a pitchlock solenoid valve located in communication with a pitchlock pressure circuit to selectively actuate pitchlocking in response to a controller. The pitchlock solenoid valve includes an electro-mechanical device which is normally closed but may be commanded to electrically open and dump the pitchlock pressure which causes actuation of the pitchlock system. The pitchlock solenoid provides a mechanism which will selectively pitchlock the propulsor system; permits a built in test routine to determine the condition of the pitchlock system through a commanded propeller pitchlock sequence; requires no mechanical link between the rotating and non-rotating propeller components to initiate pitchlock; is independent of engine and gearbox configurations; and can initiate pitchlock remotely with a signal from a remote location.
US08545174B2	Nose dome for a turbomachine rotor A nose dome for a turbomachine rotor is provided. The turbomachine rotor has an impeller which is arranged in an overhung fashion with respect to a bearing point of the turbomachine rotor. The nose dome can be connected axially to the impeller in order to guide an axial inflow and/or outflow of the impeller, and includes a coupling device. The impeller and the nose dome can be mechanically coupled radially with the coupling device, such that the vibration behavior of the turbomachine rotor may be influenced. The turbomachine with the turbomachine rotor including the nose dome is also provided. The impeller and nose dome are coupled radially using the coupling device, such that the vibration of the turbomachine rotor is damped.
US08545172B2	Turbocharger having nozzle ring locating pin and an integrated locator and heat shield A turbocharger with a variable nozzle includes a pin mounted in the center housing and extending axially therefrom and engaged in a hole in the nozzle ring to orient the nozzle ring rotationally relative to the center housing. A portion of a length of the pin has a substantially greater compliance than the remainder of the length such that the pin has a flexible tip that engages the hole in the nozzle ring. The flexible tip reduces constraint of thermal deformation of the nozzle ring. The pin portion of greater compliance can be a section of the tube that is slit and expanded. The turbocharger can also include a one-piece locator and heat shield having a locating portion abutting the center housing and the nozzle ring for radially locating the nozzle ring relative to the center housing, and having a shield portion shielding the center housing from hot exhaust gas.
US08545169B2	Cooled turbine blade for a gas turbine and use of such a turbine blade An aspect of the invention is a turbine blade for a gas turbine, comprising a blade root, adjoining which one after the other are a platform region having a transversely running platform and then a blade profile curved in the longitudinal direction, comprising at least one cavity which is open on the root side and through which a coolant can flow and which extends through the blade root and the platform region into the blade profile. The cavity is surrounded by an inner wall, on the surface of which structural elements influencing the coolant are provided. In order to prolong the service life of such a turbine blade, the invention proposes that a section, lying at least in the blade profile and adjoining the platform region, of the surface of the inner wall be free of structural elements. Such a turbine blade can preferably be used in a stationary gas turbine.
US08545167B2	Composite casing for rotating blades A gas turbine engine includes a fan including a plurality of circumferentially spaced rotatable blades, and a fan casing for containing fragments of fan blades in the event of blade release, the fan casing having a shell surrounding the blades and circumscribing a containment zone of the fan. The shell is made of a fiber reinforced polymer composite material which includes nanoparticles.
US08545163B2	Loader work machine Positional relationship among the first link support shaft (85), the second link support shaft (86), the first arm support shaft (88) and the second arm support shaft (89) is set such that an upper portion of the first lift link (81) comes into substantial agreement with a rear end of the machine body (1), when the upper free end of the first lift link (81) is pivoted maximally rearward in the course of transition of the arm (77) from a lowermost state realized lifting down the arm (77) to an uppermost state realized by lifting up the arm (77).
US08545160B2	Substrate transfer apparatus and substrate transfer method A substrate transfer apparatus that transfers a substrate with respect to a processing apparatus includes a substrate accommodation unit for accommodating a plurality of substrates to be loaded into the processing apparatus in a vertical direction in a multi-stage; a substrate accommodation unit for accommodating a plurality of substrates unloaded from the processing apparatus in a vertical direction in a multi-stage; a substrate holder for transferring the substrates from the substrate accommodation unit to the processing apparatus; a substrate holder for transferring the substrates from the processing apparatus to the substrate accommodation unit. The substrate accommodation unit has an elevating mechanism for moving at least one of the substrate and the substrate holder in a vertical direction relative to each other and the substrate accommodation unit has an elevating mechanism for moving at least one of the substrate and the substrate holder in a vertical direction relative to each other.
US08545151B2	Device and method for restraining cargo A device for engaging an elongated support for restraining cargo in a container having a pair of opposed walls and configured to transfer to shear stress at least some of the tensile force applied by the elongated support. The device comprising: a strip, a sleeve including a plurality of walls extending from the strip having an open end for receiving an end of the elongated support; gussets for transferring to shear stress at least some of the tensile force applied by the elongated support.
US08545150B2	Device and method for restraining cargo A device for engaging an elongated support for restraining cargo in a container having a pair of opposed walls and configured to transfer to shear stress at least some of the tensile force applied by the elongated support. The device comprises a strip having a bottom strip surface with an adhesive for securing the device to one of the walls, and a top strip surface. The sleeve includes four walls extending from the top strip surface defining a cavity. The sleeve having a platform within the cavity surrounded by the four walls. The platform defines within the cavity another cavity for receiving the elongated support. The platform spaces an end of the elongated support from said one of the walls of the container. An insert may be inserted into the cavity. A method of restraining cargo with the cargo restraint device.
US08545149B2	Netting arrangement for a cargo hold, in particular in an airplane, and an adapter therefor The present invention concerns a netting arrangement for a cargo hold, in particular in an airplane, comprising: at least one netting including a plurality of fixation points preferably formed on an edge side, a plurality of fixation points formed on the cargo hold side, and at least one adapter for securing the netting in the cargo hold. The adapter is secured to at least two fixation points on the cargo hold side so as to divert a load applied to the adapter into the at least two fixation points on the cargo hold side. The adapter is arranged in the path of force between the netting fixation points preferably formed on an edge side and the fixation points on the cargo hold side. The adapter furnishes at least one adapter-side fixation point for securing the netting to the adapter. The fixation points for the netting are arranged in a plane identical with the plane of the adapter-side fixation points, independently of the load applied on the netting. In the condition where no load is applied on the netting, the netting is situated in the same plane as the adapter-side fixation points. The invention moreover relates to an adapter, preferably for use with a like netting arrangement.
US08545146B2	Device to hold a work spindle The invention concerns a device to hold a motor-driven work spindle (1) in a housing of a processing machine with an outside ring (7) and an inside ring (6), arranged within the outside ring (7), so that it can be displaced and tilted axially, to hold the work spindle (1), wherein the inside ring (6) is pretensioned with respect to the outside ring (7), in an elastically resilient manner in the axial direction, by at least one pretension element (8), and wherein the inside ring (6) is held in an operating position within the outside ring (7) by a holding device with a prespecified holding force. The holding device is designed as a magnet arrangement (9) with at least one magnet (35, 36; 43), arranged in the inside ring (6) and/or the outside ring (7), for the creation of a magnetic holding force.

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