| Document | Document Title |
|---|---|
| US08525155B2 |
Phosphonium ionic liquids, compositions, methods of making and electronic devices formed there from
The invention generally encompasses phosphonium ionic liquids and compositions and their use in many applications, including but not limited to: as electrolytes in electronic devices such as memory devices including static, permanent and dynamic random access memory, as battery electrolytes, as a heat transfer medium, fuel cells and electrochromatic devices, among other applications. In particular, the invention generally relates to phosphonium ionic liquids, compositions and molecules possessing structural features, wherein the molecules exhibit superior combination of thermodynamic stability, low volatility, wide liquidus range and ionic conductivity. The invention further encompasses methods of making such phosphonium ionic liquids, compositions and molecules, and operational devices and systems comprising the same. |
| US08525154B2 |
Light-emitting device having optical resonance layer
Provided is a light-emitting device which has a simple structure and can be manufactured in a simple process, has increased light coupling efficiency and brightness, and can reduce adverse effects of optical resonance on a view angle and emission spectrum. The light-emitting device includes a substrate; a light-emitting diode formed on the substrate; and an optical resonance layer formed outside the light-emitting diode that induces resonance of light emitted from the light-emitting diode. |
| US08525152B2 |
Formation of solar cells with conductive barrier layers and foil substrates
Methods and devices are provided for absorber layers formed on foil substrate. In one embodiment, a method of manufacturing photovoltaic devices may be comprised of providing a substrate comprising of at least one electrically conductive aluminum foil substrate, at least one electrically conductive diffusion barrier layer, and at least one electrically conductive electrode layer above the diffusion barrier layer. The diffusion barrier layer may prevent chemical interaction between the aluminum foil substrate and the electrode layer. An absorber layer may be formed on the substrate. In one embodiment, the absorber layer may be a non-silicon absorber layer. In another embodiment, the absorber layer may be an amorphous silicon (doped or undoped) absorber layer. Optionally, the absorber layer may be based on organic and/or inorganic materials. |
| US08525150B2 |
Semiconductor light emission device for preventing a regional concentration phenomenon of a current flow and improving the reliability
A semiconductor light emission device is disclosed. The semiconductor light emission device includes: a substrate; a current concentration preventing pattern formed in a mesh net shape on the substrate; an n-type clad layer formed on the substrate loaded with the current concentration preventing pattern; an active layer and a p-type clad layer sequentially formed on the n-type clad layer; an n-type electrode formed on a part of the n-type clad layer which is exposed by partially etching the p-type clad layer and active layer; and a p-type electrode formed on the p-type clad layer. The current concentration preventing pattern is formed in a double layer structure which includes a first layer formed from one material of SiO and SiN and on the substrate, and a second layer formed from a metal material and on the first layer. |
| US08525148B2 |
Solid state lighting devices without converter materials and associated methods of manufacturing
Solid state lighting devices that can produce white light without a phosphor are disclosed herein. In one embodiment, a solid state lighting device includes a first semiconductor material, a second semiconductor material spaced apart from the first semiconductor material, and an active region between the first and second semiconductor materials. The active region includes a first sub-region having a first center wavelength and a second sub-region having a second center wavelength different from the first center wavelength. |
| US08525147B2 |
Semiconductor devices including a transistor with elastic channel
A semiconductor device that may control a formation of a channel is disclosed. The semiconductor device includes a gate region including a first area, an insulating layer disposed on portions of a top surface of the gate region corresponding to both ends portions of the first area, first and second electrodes formed on the insulating layer to be spaced apart from each other, an elastic conductive layer disposed between the first and second electrodes and the insulating layer and having a shape that varies according to an electrostatic force based on voltages applied to the first electrode, the second electrode, and the gate region, and a gate insulating region disposed between the elastic conductive layer and the first area of the gate region. |
| US08525141B2 |
Collimator alignment system and method
In one embodiment, a system for aligning collimators in an imaging system includes a transmitter coupled to a first detector and configured to transmit a beam, and a receiver coupled to a second detector and configured to receive the beam transmitted from the first detector. The alignment system also includes a cart comprising an alignment device with the cart configured to hold at least two collimators. The system includes a control system configured to align the first and second detectors with the at least two collimators using the alignment device. |
| US08525140B2 |
Chamber apparatus, extreme ultraviolet light generation system, and method for controlling the extreme ultraviolet light generation system
A chamber apparatus for operating with a laser apparatus includes a chamber, a target supply unit, a first optical system and a second optical system. The chamber has an inlet for introducing a laser beam thereinto. The target supply unit supplies a target material to a region inside the chamber. The first optical system focuses the laser beam in the region. The guide beam output device outputs a guide beam. The second optical system directs the guide beam such that an axis of a beam path of the guide beam substantially coincides with an axis of a beam path of the laser beam and such that the guide beam enters the focusing optical system through the region. |
| US08525135B2 |
System and method of electron beam writing
A system and method for improved electron beam writing that is capable of taking design intent, equipment capability and design requirements into consideration. The system and method determines an optimal writing pattern based, at least in part, on the received information. |
| US08525133B2 |
Particle beam irradiation system and particle beam irradiation method
A particle beam irradiation system comprising a first deflector having the maximum deflection amount which enables to move a particle beam in one direction to the maximum width of a target and a second deflector having the maximum deflection amount is less than the maximum deflection amount of the first deflector performs a control in which the particle beam is moved by increasing at least a deflection amount of the second deflector when the particle beam is moved, and performs a deflection substitution control in which a deflection of the second deflector is substituted to a deflection of the first deflector by decreasing the deflection amount of the second deflector and changing a deflection amount of the first deflector so as to make a position of the particle beam in the target dwell when the particle beam dwells. |
| US08525131B2 |
Phosphorescent organic compounds
Compositions providing metal-independent phosphorescence due to a directed heavy atom effect are provided. Methods of providing a phosphorescent composition are also provided where a directed heavy atom effect is maintained to cause the composition to be phosphorescent. Manufacture of phosphorescent compositions using intermolecular and intramolecular directed heavy atom effects are disclosed. |
| US08525129B2 |
Gas sensing device
The present invention relates to a gas sensing device comprising a nanoparticle layer (1) and a quantum dot layer (3) separated from each other by a gas absorption layer (2) which has a thickness which changes upon absorption of a gas. The nanoparticle layer (1) is provided for generating a surface plasmon resonance within a plasmon resonance frequency range upon illumination with light within a light frequency range; the quantum dot layer (3) has an absorption spectrum overlapping with said plasmon resonance frequency range of said nanoparticle layer (1) and shows photoluminescence in a photoluminescence emission frequency range upon absorption of energy within its absorption spectrum. The present invention further relates to a method for fabricating such a gas sensing device and to a method of using such a gas sensing device. |
| US08525126B2 |
UV fluid sterilizer suitable to sterilize fluid having poor UV transmission
The present invention relates to a UV fluid sterilizer, which is suitably formed to sterilize fluid having poor UV transmission. According to the present invention, the UV fluid sterilizer includes a plurality of UV sterilization units. The UV sterilization units include: small quartz tubes; inside UV lamps mounted in the small quartz tubes for radiating UV rays at the inside of fluid; large quartz tubes concentrically mounted outside the small quartz tubes for forming the flow spaces of the fluid; spring type coils spirally fixed to the outer diameter surfaces of the small quartz tubes for applying rotation force to the fluid; and UV transmission shrinks films for fixing the spring type coils to the outer diameter surfaces of the small quartz tubes in close contact and preventing foreign substances from being trapped in the flow spaces of the fluid, and are characterized in that a plurality of outside UV lamps are provided outside the large quartz tubes for radiating UV rays to the fluid, which flows through the UV sterilization units, from the outside. |
| US08525115B1 |
Method of local electro-magnetic field enhancement of terahertz (THZ) radiation in sub-wavelength regions and improved coupling of radiation to materials through the use of the discontinuity edge effect
A method and apparatus for enhanced THz radiation coupling to molecules, includes the steps of depositing a test material near the discontinuity edges of a slotted member, and enhancing the THz radiation by transmitting THz radiation through the slots. The molecules of the test material are illuminated by the enhanced THz radiation that has been transmitted through the slots, thereby producing an increased coupling of EM radiation in the THz spectral range to said material. The molecules can be bio-molecules, explosive materials, or species of organisms. The slotted member can be a semiconductor film, a metallic film, in particular InSb, or layers thereof. THz detectors sense near field THz radiation that has been transmitted through said slots and the test material. |
| US08525114B2 |
Standoff explosives detection
The present invention may include methods and apparatus for the detection of explosives using near infrared or infrared spectroscopy to detect nitro or even carbonyl groups. Embodiments may include, at least one radiation emitter may emit at least one wavelength towards a target. At least one reflected wavelength may be generated after the wavelength collides with the target. A reflected wavelength may then be detected by at least one detector and analyzed with an analyzer. |
| US08525113B2 |
Portable radiometric imaging device and a corresponding imaging method
The invention relates to a portable radiometric imaging device and to a corresponding method, finding a particular application in detecting articles carried by passengers or contained in baggage, for example in airports and train stations. The device includes a plurality of receiver antennas for picking up electromagnetic radiation from a plurality of parts of a body or an article and converting them into a plurality of signals representative of said radiation, a plurality of receiver modules associated with the antennas for receiving the signals representative of the radiation and converting them into a plurality of electrical signals, and a digital processor unit for responding to the electrical signals to create one or more digital signals representative of the electromagnetic radiation for display on a display as an image of the body or article. A correlator module is provided for correlating the electrical signals in order to form a signal representative of the electromagnetic radiation from the intersection of the two parts of the body or article. |
| US08525112B2 |
Variable pixel density imaging
A method and associated apparatus for topographically characterizing a workpiece. The workpiece is scanned with a scanning probe along a first directional grid, thereby scanning a reference surface and an area of interest subportion of the reference surface, at a variable pixel density including a first pixel density outside the area of interest and a second pixel density inside the area of interest to derive a first digital file characterizing topography of the workpiece. The workpiece is further scanned along the reference surface and the area of interest with the scanning probe along a second directional grid that is substantially orthogonal to the first directional grid and at a constant pixel density to derive a second digital file characterizing topography of the workpiece. A processor executes computer-readable instructions stored in memory that generate a topographical profile of the workpiece in relation to the first and second digital files. |
| US08525111B1 |
High pressure mass spectrometry systems and methods
Mass spectrometers and methods for measuring information about samples using mass spectrometry are disclosed. |
| US08525108B2 |
Mass spectrometer
The mass spectrometer is characterized in that a linear ion trap, that consists of electrodes for mass-selective discharge, is provided with a mechanism that excites ions in a first direction that is perpendicular to the rod axes and a mechanism that simultaneously generates an electric field on the axes in a second direction that is perpendicular to the axial direction and the first direction in order to generate an electric field on the central axis. Highly efficient, high-speed scanning can be achieved using this configuration. |
| US08525104B2 |
Methods for direct biomolecule identification by matrix-assisted laser desorption ionization (MALDI) mass spectrometry
The present invention relates to the use of post source decay (PSD) or collision induced dissociation (CID) direct tissue (DT) MALDI-TOF or DT-MALDI-TOF-TOF mass spectrographic identification of biological molecules in a tissue or cellular sample without the need for further protein extraction. This method provides for studying cells or tissues by direct tissue MALDI (DT-MALDI), thereby substituting in situ protein release for further protein extraction. Mass/intensity data was processed with Mascot© software interrogation of the NCBI database. These results are proof of principle that DT-MALDI, combined with bioinformatics, can directly identify proteins in cells and tissues from their mass spectra. |
| US08525102B2 |
Optical encoding system and optical encoder having an array of incremental photodiodes and an index photodiode for use in an optical encoding system
An optical encoder is disclosed. Specifically, a three-channel encoder is disclosed which utilizes a single track for all three channels. An index channel is provided on the same optical track as the first and second channels which are used to determine incremental angular position. Thus, a more compact and simple three-channel encoder is provided. |
| US08525099B2 |
Temporal based motion sensor reporting
Methods and systems may include a motion sensor and logic to sample an output signal of the motion sensor. The logic can also be configured to track an amount of time the motion sensor is triggered based on the output signal, and transmit the amount of time over a wireless link on a periodic basis. |
| US08525097B2 |
Wireless laser system for power transmission utilizing a gain medium between retroreflectors
An optical power beam transmission systems, with a directional light transmitter and receiver. The transmitter contains an amplifying laser medium, and this together with a retroreflector in the receiver, forms a laser resonator. When lasing sets in, the receiver can extract optical power through an output coupler and convert it to electrical power. The gain medium may be a disc having a thickness substantially smaller than its lateral dimensions. The laser resonator is operated as a stable resonator to ensure safe operation. This is achieved by use of an adaptive optical element, for reducing the diameter of the energy beam impinging on the gain medium, thereby increasing the overlap between the energy beam and the gain medium. As the transmitter-receiver distance is changed, such as by movement of the receiver, the adaptive optical element focal length changes to ensure that the cavity remains within its stability zone. |
| US08525095B2 |
Nanothermocouple detector based on thermoelectric nanowires
A nanothermocouple detector includes a nanowire coupled across two electrodes. The two electrodes are electrically connected to an amplifier. The two electrodes generally have a separation of about five micrometers to about thirty micrometers across which the nanowire is coupled. A focusing element is disposed to admit photons that fall on the focusing element onto the nanowire to heat it. A voltage change across the nanowire caused by the heating of the nanowire by the light is detected by the amplifier. The voltage change corresponds to the energy absorbed from the light by the nanowire. The color of a single photon can be detected using such device. An array of such devices can be used for sensing light on a two-dimensional scale, thereby providing an image showing small variances in the energies of the light impinging upon the detector array. |
| US08525092B2 |
Data processing method and solid-state image pickup device
A data processing method may include counting one of a plurality of clock signals with a first mode, counting clock signals based on a predetermined number of the plurality of clock signals with the first mode, to output a first clock signal every time a counter value becomes a first predetermined value, counting the first clock signal with the first mode, counting one of the clock signals with a second mode while the counted value is considered as a first initial value, counting clock signals based on the predetermined number of the plurality of clock signals with the second mode, to output a second clock signal every time the counter value becomes a second predetermined value while the counted value is considered as a second initial value, counting the second clock signal with the second mode, and outputting the counter values with the second mode as difference data between a first data signal and a second data signal. |
| US08525089B2 |
Wing device and flight vehicle having the same
Disclosed are a wing device for a flight vehicle and a flight vehicle having the same, the wing device including a fixing shaft disposed in a lengthwise direction of a main body of the flight vehicle, a wing rotatably mounted to the fixing shaft so as to be deployed from a state of being laid on an outer circumferential surface of the main body to an erected state, and slidable along the fixing shaft, a fixing groove formed to face the wing in a sliding direction of the wing, and a spring unit configured to apply a first elastic force in an outer circumferential direction of the main body for deployment of the wing, and apply a second elastic force in a lengthwise direction of the main body for inserting the wing into the fixing groove, whereby the wing can be fixed after deployment so as to enhance stability of the flight vehicle. |
| US08525085B2 |
Directed energy melter
The melter includes a vessel and structure for introducing waste material into the vessel. Waveguide structure is provided for introducing millimeter wave electromagnetic radiation into the vessel to heat the waste material. A gyrotron is a preferred source for the millimeter wave electromagnetic radiation. |
| US08525084B2 |
Electrical heating element
An electrical device includes a compound material. The compound material includes a mixture of an electrically conductive material and an electrically insulative material. The conductive material is aligned within the compound material, such that the resistivity of the compound material in a first direction is different from the resistivity of the compound material in a second direction perpendicular to the first direction. |
| US08525083B2 |
Water heater with power consumption reporting
A hot water heater and method that includes power consumption reporting to enable consumers to better understand and control the energy usage and/or efficiency of the hot water heater. Monitoring energy consumption of an electric hot water heater having at least one electrical load that is selectively activated by a controller of the hot water heater includes sensing the amount of time the at least one electrical load is activated multiplying the amount of time by a known value corresponding to a power rating of the electrical load to determine energy consumed, and displaying on a display device an indicator corresponding to the energy consumed. |
| US08525082B2 |
Method for performing an automatic cooking process
The present invention relates to a method for performing an automatic cooking process in an oven, wherein the oven is in a preheated state with a first starting temperature (T0) in the beginning of said automatic cooking process. The method includes the following steps of switching off at least one heating element during a cooling down period (10) and finishing the cooling down period (10) after a cooling down time (tcd), when a predetermined first end temperature (T1) has been reached. The cooling down time (tcd) is detected. The method includes the further steps of switching on at least one heating element during a heating up period (12) and finishing the heating up period (12) after a heating up time (thu) and/or when a predetermined second end temperature (T3) has been reached. A mathematical function (14) including the cooling down time (tcd) and the heating up time (thu) is used in order to determine further parameters of the cooking process. |
| US08525081B2 |
Food steamer containers with sequential ohmic water heating
A liquid heating system includes an electric current controller, a first container, and a second container. The first container includes a first liquid and a first electric heating system. The second container includes a second liquid and a second electric heating system. The electric current controller is connected to the first electric heating system and to the second electric heating system. The electric current controller is configured to automatically alternate between providing electric current to the first electric heating system and to the second electric heating system such that when the electric current controller is providing the current to the first electric heating system the electric current controller provides no electric current to the second electric heating system and when the electric current controller is providing the current to the second electric heating system the electric current controller provides no electric current to the first electric heating system. |
| US08525079B2 |
Flat heating element
This invention relates to a flat heating element in particular for heating surfaces in contact with the user in the passenger compartment of a vehicle, comprising at least one electrical conductor. According to the invention, the electrical conductivity of at least one of these electrical conductors is at least temporarily reduced if the temperature thereof at least locally exceeds a permissible maximum temperature. |
| US08525075B2 |
Laser irradiation apparatus
The present invention is to provide a laser irradiation apparatus for forming a laser beam which has a shape required for the annealing and which has homogeneous energy distribution, by providing a slit at an image-formation position of a diffractive optical element, wherein the slit has a slit opening whose length is changeable.The laser irradiation apparatus comprises a laser oscillator, a diffractive optical element, and a slit, wherein the slit has a slit opening whose length in a major-axis direction thereof is changeable, wherein a laser beam is delivered obliquely to a substrate, and wherein the laser beam is a continuous wave solid-state, gas, or metal laser, or a pulsed laser with a repetition frequency of 10 MHz or more. |
| US08525070B2 |
Laser irradiation apparatus, laser irradiation method, and method for manufacturing semiconductor device
A laser irradiation apparatus is provided with a laser oscillator, an articulated beam propagator in which a plurality of pipes are connected to each other in an articulated portion, and a course change means of a laser beam in the articulated portion. At least one pipe of the plurality of pipes includes a transfer lens for suppressing stagger of a laser beam in a traveling direction, in each pipe. The articulated portion produces degree of freedom in disposition of a laser oscillator, and the transfer lens enables suppression of change in beam profile. |
| US08525068B2 |
Plasma torch with swirl-inducing nozzle and method of using same
A plasma torch 1 used in plasma-arc welding is provided with a rod-shaped electrode 10, a first cylindrical nozzle 11 which is provided to surround the electrode 10 and which injects a plasma gas and a second cylindrical nozzle 12 which is provided to surround the first nozzle 11 and which injects a shielding gas. A second injection opening 121 of the second nozzle 12 directs in a substantially parallel direction with respect to an axial direction of the electrode 10 or in a direction being away from the electrode 10, and a plurality of groove portions inclining with respect to the axial direction of the electrode 10 are formed in an outer circumferential surface of the first nozzle 11 or an inner circumferential surface of the second nozzle 12. |
| US08525066B2 |
Electrode for spot welding
Spot welding electrodes with generally dome shaped welding faces are provided with surface features for welding both aluminum alloy sheet assemblies and steel sheet assemblies. A raised circular plateau is formed on the central axis of the dome and, in one embodiment, a suitable number of round bumps are formed in concentric spacing from adjacent the circumference of the plateau toward the circular edge of the welding face. For welding steel workpieces the plateau mainly serves as the engaging feature of the electrode. Both the plateau and concentric bumps are used in penetrating light metal surfaces for suitable current passage. In another embodiment, the domed surface is shaped with concentric terraces for engagement with the workpieces. |
| US08525065B2 |
Electric discharge machining apparatus and programming device
An electric discharge apparatus includes electrode specification input means for inputting each electrode specification of a plurality of integral electrode where electrodes corresponding to a plurality of machining forms are arranged continuously on the same axis, machining detail input means for inputting data of a workpiece when electric discharge machining is performed using the integral electrode, and a machining program generation means for generating a machining program consisting of machining start position and a machining depth when electric discharge machining is performed using each electrodes based on the electrode specification and the thickness data of the workpiece thus input. There are further provided electrode specification input means and the machining detailed input means capable of inputting thereinto the following information: which part of the integral electrodes acts for rough machining and which part acts for finish machining, whether a finishing electrode is provided at one position or two positions, in what position relation they are, and how much the thickness of the workpiece is. Therefore, manual calculation by a worker is not required and a program can be made automatically only by inputting these parameters. |
| US08525063B2 |
Wire electric discharge machining apparatus
A wire electric discharge machining apparatus for machining a workpiece (7) by supplying current pulses to a work gap formed between a wire electrode (8) and the workpiece comprises a person detection sensor (10) for generating a person detection signal (EX) when the existence of a person is detected, and an NC device (20) that is configured to receive the person detection signal. When the NC device receives the person detection signal, it selects first machining conditions which improve machining speed. When the NC device does not receive the person detection signal, it selects second machining conditions which reduce the risk of wire breakage. |
| US08525061B2 |
Self-pressurized arc diverter
A self-pressurized arc diverter includes a vessel configured to enclose a fusible member disposed in a conductor and a pressure-activated arc diverter. The pressure-activated arc diverter is configured to provide access to a preferred arc path when actuated by pressure in the vessel caused by an arc that is created when the fusible member opens. |
| US08525060B2 |
Input device with swing operation
An input device includes a printed circuit board for outputting a signal, a supporting base fixed on the printed circuit board, a metal dome switch installed on the printed circuit board, and a cap pivoted to the supporting base. A protrusion is formed on an end of the cap for contacting against the printed circuit board when the cap is not pressed down. The cap pivots relative to the supporting base when the cap is pressed down. An actuator is further formed on the cap and disposed on a side of the metal dome switch. The actuator of the cap presses down the metal dome switch to actuate the metal dome switch when the cap is pressed down. |
| US08525059B2 |
Handpiece finger switch for actuation of handheld medical instrumentation
A handpiece for a medical instrumentation device is formed with manually deformable ribs on an outer sleeve. The ribs align with conductive surfaces inside the handpiece that make contact with an internal flexible electronic circuit to activate the device when force is applied to the ribs. Removing the force deactivates the device. |
| US08525057B2 |
Switching unit for a circuit breaker having a rocker lever
An exemplary switching unit is disclosed for operation of a rocker lever of a circuit breaker, which is provided on the circuit breaker. The switching unit has a drive unit with a free-play distance, such that a slide of the drive unit, which slide is intended for operation of the rocker lever, does not impede the movement of the rocker lever. |
| US08525056B2 |
Hold switch
This invention is directed to a switch for use in an electronic device. As the user actuates the switch, different labels may be visible to indicate to the user the current state of the switch. To allow the switch to be positioned adjacent to an edge of the device, the switch may include only a single label that moves with the switch. For example, the switch may include a label positioned adjacent to a nub that the user may operate. The label may be sized such that only the label is visible when the switch is in a first position. The electronic device may also include a second label that is fixed to a non-moving portion of the electronic device. When the user moves the switch, the switch may move away from and uncover the second label while hiding the label that is included in the switch. |
| US08525049B2 |
Combination weigher having reduced batch time and improved operational speed
A combination weigher capable of high-speed operation comprises plural weighing units each of which includes a weighing hopper group including plural weighing hoppers arranged along an inner side of an imaginary circle and fed with objects; and a collecting chute disposed below the weighing hopper group and configured to collect the objects discharged from the weighing hoppers and to discharge the objects from a discharge outlet at a bottom part thereof, wherein weighing hopper groups of the respective weighing units include plural weighing hoppers arranged on inner sides of different imaginary circles, the different imaginary circles partially overlap with each other, and the weighing hoppers are not disposed in circular-arc regions of the imaginary circles corresponding to the overlapping region of the different imaginary circles. |
| US08525048B2 |
Combination weigher having improved combination hopper access
A combination weigher capable of performing a high-speed operation regardless of a characteristic of a weighed object comprises plural weighing units and a lower collecting chute and a lower collecting hopper which collect the objects which have been discharged from upper collecting hoppers of weighing units and discharge them, and a control unit. The control unit repetitively performs a process for determining a discharge combination from weighing hoppers in all weighing units, a process for causing weighing hoppers making up the discharge combination to discharge the objects, a process for causing all of the upper collecting hoppers to discharge the objects; and a process for causing the lower collecting hopper to discharge the objects. |
| US08525047B2 |
Electrical feed-through for hermetic compressors
An electrical feed-through includes an electrically conductive connection pin and an elastic insulation member coupled to the connection pin by vulcanizing the insulation member, wherein the coupled connection pin and insulation member are arranged in an opening of a casing and pressure-tightly clamped in the opening by a fastening element. |
| US08525045B2 |
Faraday cage and device having same
A Faraday cage includes a casing structured by a first housing having a first outer cover made of a conductive material, and a first inner cover made of a conductive material, which is accommodated in the first outer cover and is electrically insulated from the first outer cover, and a second housing having a second outer cover made of a conductive material, which fits the first outer cover, and a second inner cover made of a conductive material, which is accommodated in the second outer cover and is electrically insulated from the second outer cover, the first and second housings being separable from each other; and a filter cartridge disposed inside the casing configured to be separable into two pieces, which accommodates therein a first filter for collecting fine particles sucked in from the outside the casing. |
| US08525039B2 |
Photosensitive glass paste and multilayer wiring chip component
A photosensitive glass paste that can be fired at a low temperature for a short period of time and that can suppress generation of voids and diffusion of Ag in glass layers formed by firing, and a high-performance multilayer wiring chip component manufactured by using the above photosensitive glass paste are provided. As a sintering aid glass which is combined with a ceramic aggregate and a primary glass, a glass having a contact angle to the ceramic aggregate smaller than that of the primary glass to the ceramic aggregate is used, and the content of the sintering aid glass is set to 5 to 10 percent by volume of the inorganic component. As the sintering aid glass, a glass containing SiO2, B2O3, CaO, Li2O, and ZnO at a predetermined ratio is preferably used. As the primary glass, a glass containing 70 to 90 percent by weight of SiO2, 15 to 20 percent by weight of B2O3, and 1 to 5 percent by weight of K2O can be used. |
| US08525036B2 |
Wireless telemetry electronic circuit board for high temperature environments
A circuit assembly (34) resistant to high-temperature and high g centrifugal force is disclosed. A printed circuit board (42) is first fabricated from alumina and has conductive traces of said circuit formed thereon by the use of a thick film gold paste. Active and passive components of the circuit assembly are attached to the printed circuit board by means of gold powder diffused under high temperature. Gold wire is used for bonding between the circuit traces and the active components in order to complete the circuit assembly (34). Also, a method for manufacturing a circuit assembly resistant to elevated temperature is disclosed. |
| US08525032B2 |
Device for decreased risk of dielectric breakdown in high voltage apparatuses
A device including a corona shield, and at least one support element for connecting the corona shield to a high voltage apparatus. The at least one support element includes a semiconducting polymer, which, when in operation, acts as a resistance between the corona shield and the high voltage apparatus. Furthermore the support element is arranged to fix the corona shield to the high voltage apparatus. |
| US08525025B2 |
High voltage direct current cable termination apparatus
A direct current cable termination apparatus for terminating a high voltage direct current cable. The apparatus includes a current-carrying device including a terminal portion of the direct current cable, the cable including an electrical conductor, an electrically insulating layer located outside of the electrical conductor, and a conductive shield located outside of the insulating layer and the electrical conductor; and a housing including a tubular outer shell with an inner periphery and formed by an electrically insulating and polymer-containing material. The current-carrying device is adapted to extend in the axial direction of the outer shell. Along at least a part of the axial extension of the current-carrying device the outer shell extends axially with a space between its inner periphery and the current-carrying device. |
| US08525021B2 |
Photovoltaic devices including heterojunctions
A photovoltaic cell can include a heterojunction between semiconductor layers. The first semiconductor layer can include a III-V compound semiconductor, the first semiconductor layer positioned over a transparent conductive layer. A second semiconductor layer can include a II-VI compound semiconductor, the second semiconductor layer positioned between the first semiconductor layer and a back metal contact. |
| US08525019B2 |
Thin film article and method for forming a reduced conductive area in transparent conductive films for photovoltaic modules
A method for forming a reduced conductive area in transparent conductive. The method includes providing a transparent, electrically conductive, chemically reducible material. A reducing atmosphere is provided and concentrated electromagnetic energy from an energy source is directed toward a portion of the transparent, electrically conductive, chemically reducible material to form a reduced conductive area. The reduced conductive area has greater electrical conductivity than the transparent, electrically conductive, chemically reducible material. A thin film article and photovoltaic module are also disclosed. |
| US08525018B2 |
Solar cell
A solar cell is discussed. The solar cell includes a substrate of a first conductive type, an emitter region of a second conductive type opposite the first conductive type that is positioned on the substrate, a first field region of the first conductive type that is positioned on the substrate to be separated from the emitter region, a first electrode electrically connected to the emitter region, a second electrode electrically connected to the first field region, and an insulating region positioned on at least one of the emitter region and the first field region. |
| US08525017B2 |
Sealing material for solar battery, sheet for sealing solar battery, and solar battery module using the same
[Task] To provide a solar battery sealing material obtained by using an olefin-based (co)polymer, which is excellent in flexibility, stress-absorbing property, transparency, and impact-resistant strength at low temperature, and with which the productivity is improved by omitting a cross-linking treatment if necessary.[Solving Means] A solar battery sealing material containing 1 to 40 parts by weight of polypropylene (i) which has a propylene unit of more than 90 mol %; and 60 to 99 parts by weight of a propylene.ethylene-based copolymer (ii) which has a propylene unit of 45 to 90 mol %, an ethylene unit of 10 to 25 mol %, and an α-olefin unit (a) having 4 to 20 carbon atoms of 0 to 30 mol % ((i)+(ii)=100 parts by weight). The solar battery sealing material further contains 5 to 95 parts by weight of an ethylene.α-olefin copolymer (B), based on 95 to 5 parts by weight of the total amount of (i) and (ii) ((i)+(ii)+(B)=100 parts by weight). |
| US08525010B2 |
Portable drum
A portable drum that includes a drum head and a detachable dram shell, where the drum head may include an upper drum head and a detachable lower dram head and the dram shell may include one or more detachable sections. Once assembled, the upper drum head, the detachable lower dram head, and the sections of the dram shell may be held in place by a tensioning system that may include vertical straps and a waist belt strap. The portable dram may be disassembled and placed in a travel mode by nesting the sections of the dram shell in the lower dram head, and then placing the lower dram head into the upper dram head. |
| US08525007B2 |
Action of upright piano
To provide an action of an upright piano which permits playing of repeated notes on the single key and touch of the keys that are comparable to a grand piano. A first spring (59) is provided to a pushing-up portion (20) of a jack (18), a first spring rest (71) is provided to a jack stop rail (53), and when a jack tail (19) moves away from a regulating button (47), the first spring (59) bent between the pushing-up portion (20) and the first spring rest (71) forces the pushing-up portion (20) to be pushed under a pushed-up portion (27) to be thrust up of a hammer butt (25). A second spring (66) is provided to a damper stop rail (56), a second spring rest (72) is provided to a hammer shank (33), and the second spring (66) bent between the damper stop rail (56) and the second spring rest (72) stops the rotational movement of a hammer (32) before the hammer (32) that moves rotationally by the force of the first spring (59) strikes a string (90). |
| US08525004B2 |
Soybean variety D6854249
The invention relates to the soybean variety designated D6854249. Provided by the invention are the seeds, plants and derivatives of the soybean variety D6854249. Also provided by the invention are tissue cultures of the soybean variety D6854249 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety D6854249 with itself or another soybean variety and plants produced by such methods. |
| US08525001B2 |
Plants and seeds of hybrid corn variety CH948307
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH948307. The invention thus relates to the plants, seeds and tissue cultures of the variety CH948307, and to methods for producing a corn plant produced by crossing a corn plant of variety CH948307 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH948307. |
| US08525000B2 |
Plants and seeds of hybrid corn variety CH407490
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH407490. The invention thus relates to the plants, seeds and tissue cultures of the variety CH407490, and to methods for producing a corn plant produced by crossing a corn plant of variety CH407490 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH407490. |
| US08524997B1 |
Maize variety inbred PH1CRD
A novel maize variety designated PH1CRD and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1CRD with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1CRD through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1CRD or a locus conversion of PH1CRD with another maize variety. |
| US08524995B1 |
Inbred corn line NPAF3107
Basically, this invention provides for an inbred corn line designated NPAF3107, methods for producing a corn plant by crossing plants of the inbred line NPAF3107, with plants of another corn plant. The invention relates to the various parts of inbred NPAF3107, including culturable cells. This invention also relates to methods for introducing transgenic transgenes into inbred corn line NPAF3107, and plants produced by said methods. |
| US08524993B2 |
Celery cultivar ADS-20
A celery cultivar, designated ADS-20, is disclosed. The invention relates to the seeds of celery cultivar ADS-20, to the plants of celery cultivar ADS-20 and to methods for producing a celery plant by crossing the cultivar ADS-20 with itself or another celery cultivar. The invention further relates to methods for producing a celery plant containing in its genetic material one or more transgenes and to the transgenic celery plants and plant parts produced by those methods. This invention also relates to celery cultivars or breeding cultivars and plant parts derived from celery cultivar ADS-20, to methods for producing other celery cultivars, lines or plant parts derived from celery cultivar ADS-20 and to the celery plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid celery seeds, plants, and plant parts produced by crossing cultivar ADS-20 with another celery cultivar. |
| US08524991B2 |
Pepper hybrid PX11435810
The invention provides seed and plants of pepper hybrid PX11435810 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of pepper hybrid PX11435810 and the parent lines thereof, and to methods for producing a pepper plant produced by crossing such plants with themselves or with another pepper plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants. |
| US08524988B1 |
Soybean cultivar NE0912636
The present invention is in the field of soybean variety NE0912636 breeding and development. The present invention particularly relates to the soybean variety NE0912636 and its progeny, and methods of making NE0912636. |
| US08524983B1 |
Soybean cultivar 05RM300035
The present invention is in the field of soybean cultivar 05RM300035 breeding and development. The present invention particularly relates to the soybean cultivar 05RM300035 and its progeny, and methods of making 05RM300035. |
| US08524981B2 |
Lactuca sativa cultivar solid king
According to the invention, there is provided a novel romaine lettuce cultivar, designated Solid King. ‘Solid King’ is described as a vigorous romaine cultivar with large frame size and heavier weight, short core length, savoyed and glossy leaf color, corky root rot resistance, no fringe burn on mature leaves and also yellower heart leaf color with a solid mid rib. This invention thus relates to the seeds of lettuce cultivar Solid King, to the plants of lettuce cultivar Solid King, to plant parts of lettuce cultivar Solid King, to methods for producing a lettuce cultivar by crossing the lettuce cultivar Solid King with another lettuce cultivar, and to methods for producing a lettuce cultivar containing in its genetic material one or more backcross conversion traits or transgenes and to the backcross conversion lettuce plants and plant parts produced by those methods. |
| US08524980B2 |
Composition and method to alleviate joint pain
Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and/or rheumatoid arthritis have been found with krill oil and/or marine oil in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form. |
| US08524979B2 |
Termination of transgene expression via transposon-mediated break
This invention provides a genetic construct comprising: (a) a DNA cut-and-paste transposon genetic unit which comprises a transposase gene flanked on either side by inverted repeat sequences and operably under the control of a first promoter; and (b) a transgene unit which comprises an expressable transgene, placed operably under the control of a second promoter; wherein the transposon genetic unit and the transgene unit are linked with one of the inverted repeat sequence located in an intron of the transgene. This invention also provides methods of transiently expressing a transgene in a stably transformed eukaryote. This invention further provides methods for obtaining marker-free transgenic plants. |
| US08524978B2 |
Composition for production of plant body having improved sugar content, and use thereof
The composition, in accordance with the present invention, for producing a plant body having an improved sugar content includes glutathione, a polynucleotide encoding γ-glutamylcysteine synthetase, or a polynucleotide encoding glutathione-binding plastid type fructose-1,6-bisphosphate aldolase. The composition preferably includes oxidized glutathione. This allows provision of a composition for easily producing a plant body having an improved sugar content. |
| US08524976B2 |
Iduronidase knock-out mouse
The present invention relates to a α-L-iduronidase knock-out mouse. More particularly, this invention relates to a α-L-iduronidase knock-out mouse to be designed for developing a treatment or an agent for mucopolysaccharidosis type I (Hurler syndrome or Hurler-Scheie syndrome) as an animal model. |
| US08524975B2 |
Method of predicting a behavior of one or more drugs
The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes or portions of genes have been replaced by homologues from another animal to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies. |
| US08524974B2 |
Hemostatic device
A hemostatic device includes a flexible band adapted to be wrapped around a patient's limb at a site on the limb where bleeding is to be stopped, a portion for securing the band in a wrapped state to the limb, a curved plate which is made of a material more rigid than the band and at least a portion of which is curved toward the inner peripheral side thereof, a main balloon which is provided on the inner peripheral side of the curved plate and which inflates when a fluid is introduced therein, and a pressing member which is provided between the curved plate and the main balloon so that at least a portion thereof overlaps with the balloon and which is adapted for pressing against the balloon. The device provides an excellent hemostatic effect and prevents numbness and poor circulation in areas peripheral to the site of attachment. |
| US08524973B2 |
Wound and therapy compress and dressing
The invention provides a wound dressing or therapy compress (100) containing a fill material (108) permanently loaded with an antimicrobial silver. The dressing or compress comprises a flexible upper backing (104) and a lower shell (102) fastened to one another, and each of which comprises a synthetic fabric. The lower shell is fluid-permeable and is adapted to be placed in direct or covered contact with a wound or tissue to be treated. The backing may be either fluid permeable or non-permeable, as desired, to allow for the release or retention of moisture. The shell and backing are joined to one another to form a plurality of fill material enclosures (106) therebetween, each such fill material enclosure containing a zeolite fill material which is permanently loaded with antimicrobial silver. The presence of the silver within the fill material promotes a germ and microbial free environment approximate the shell and within the dressing or compress. So constructed, the dressing or compress may be used to cover and protect a wound while absorbing exudate, and may also provide and maintain a heated and/or a moist environment to promote the healing of wounds. |
| US08524970B2 |
Process and plant for producing synthetic fuels
In a process for producing synthetic fuels from an educt mixture containing hydrogen and oxygenates, such as methanol and/or dimethyl ether, the educt mixture is reacted on a catalyst in a first process stage to obtain a hydrocarbon product containing olefins with preferably 2 to 8 carbon atoms. In a second process stage the hydrocarbon product is oligomerized to long-chain olefins, from which gasoline and Diesel products are obtained. The hydrocarbon product obtained in the first process stage is separated into a liquid phase and a gaseous phase. The gaseous phase is supplied to the second process stage. The liquid phase is separated into a mixture rich in C6− hydrocarbons and a mixture containing C7+ hydrocarbons and aromatics. The mixture rich in C6− hydrocarbons is supplied to the second process stage. The mixture containing C7+ hydrocarbons −+ and aromatics can be admixed to the gasoline product for quality improvement. |
| US08524969B2 |
Dehydrogenation reactions of hydrocarbons to alkenes
A method for the dehydrogenation of hydrocarbons to alkenes, such as n-pentene to piperylene and n-butane to butadiene at pressures less than atmospheric utilizing a dehydrogenation catalyst are disclosed. Embodiments involve operating the dehydrogenation reactor at a pressure of 1,000 mbar or less. |
| US08524966B1 |
Catalysts for improved cumene production and method of making and using same
An aromatic alkylation catalyst is presented. The aromatic alkylation catalyst comprised a zeolite, an inorganic oxide, and silanol functional groups of less than about 0.65 area/mg on the surface of the catalyst. |
| US08524964B2 |
Hydrocarbon conversion process using EMM-10 family molecular sieve
This disclosure relates to a process for hydrocarbon conversion comprising contacting, under conversion conditions, a feedstock suitable for hydrocarbon conversion with a catalyst comprising an EMM-10 family molecular sieve. |
| US08524960B2 |
Fluid catalytic cracking of oxygenated compounds
A process is disclosed for fluid catalytic cracking of oxygenated hydrocarbon compounds such as glycerol and bio-oil.In the process the oxygenated hydrocarbon compounds are contacted with a fluid cracking catalyst material for a period of less than 3 seconds.In a preferred process a crude-oil derived material, such as VGO, is also contacted with the catalyst. |
| US08524955B2 |
Process for the preparation of hexafluoro-2-butyne
Disclosed is a process for making hexafluoro-2-butyne comprising the steps of: (a) providing a composition comprising CF3CX═CXCF3, where X=halogen; and (b) treating CF3CX═CXCF3 with a dehalogenation catalyst in the presence of a halogen acceptor compound Y, where Y is not hydrogen. The halogen acceptor compound Y is a material capable of being halogenated, preferably a compound having a multiple bond, such as an alkyne, alkene, allene, or carbon monoxide. Another suitable material capable of being halogenated is a cyclopropane. A catalyst effectively transfers halogen from CF3CX═CXCF3 to the halogen acceptor compound. Since Y is not hydrogen, the formation of CF3CX═CHCF3 is greatly reduced or eliminated. |
| US08524948B2 |
Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
The present invention relates to non-steroidal ligands for use in nuclear receptor-based inducible gene expression system, and a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene. |
| US08524944B2 |
Process for the preparation of sodium gamma-hydroxybutyrate
The present invention is directed to a process for the preparation of the saponification products of lactones, preferably three- to eight-membered lactones. The present invention is also directed to a process for the preparation of compounds having general formula (I): wherein M is selected from the group consisting of cationic species, preferably metal cations (even more preferably Na), from a compound having the formula (II): comprising reacting a compound having formula (II) with a suitable hydroxide salt (M-OH) (III) such as, preferably, sodium hydroxide, in an aqueous medium. The reaction preferably utilizes a continuous process method for the substantial consumption of reagent and continuous, semi-continuous, and/or batch-wise processing for final consumption of reagent. |
| US08524935B2 |
Method for preparing fluoroalkanesulphinic acid esters
A method for preparing fluoroalkanesulphinic acid esters is described. The preparation of esters of trifluoromethanesulphinic acid, commonly referred to as “triflinic acid,” is also described. A method for preparing a fluoroalkanesulphinic acid ester is also described wherein the method includes reacting a fluoroalkanesulphinic acid with an organic carbonate leading to the formation of a fluoroalkanesulphinic acid ester and carbon dioxide, which is removed during the reaction. |
| US08524934B2 |
Silicone compositions and methods for preparing them
A silicone composition comprising a formula: (M1)a(D1)b(D2)c wherein M1=R1R2R3SiO1/2; D1=R4R5SiO2/2; and D2=R6R7SiO2/2; wherein R1 is independently at each occurrence a monovalent hydrocarbon radical comprising a reactive end- group other than an amino group; R6 comprises a monovalent poly(oxyalkyl) hydrocarbon radical; and R2, R3, R4, R5, and R7 are independently monovalent hydrocarbon radicals; wherein a, b, and c are stoichiometric subscripts that are zero or positive subject to the following limitations: a is greater than or equal to 2; c is greater than or equal to 1; and when b=0, a+c is greater than or equal to 3 is disclosed. |
| US08524932B2 |
Process for preparing porous metal-organic frameworks based on aluminum fumarate
The present invention relates to a process for preparing a porous metal-organic framework comprising at least one at least bidentate organic compound coordinated to at least one metal ion, where the at least one metal ion is based on an aluminum ion and the at least one at least bidentate organic compound is based on fumaric acid, by reacting at least one aluminum compound with at least fumaric acid in an alkaline aqueous medium, optionally in the presence of at least one base, at a temperature in the range from 20° C. to 100° C. at an absolute pressure of not more than 2 bar for from 0.2 to 4 hours. |
| US08524929B2 |
Extraction with fractionation of lipids and proteins from oleaginous material
Systems and methods for extracting lipids of varying polarities from oleaginous material. |
| US08524927B2 |
Process for making ethylene oxide using microchannel process technology
This invention relates to a process comprising reacting ethylene and oxygen or a source of oxygen in a process microchannel in the presence of a catalyst to form a product comprising ethylene oxide. |
| US08524925B2 |
Production of furfural from biomass
Processes for producing furfural from biomass are provided. The processes use a metal halide in aqueous solutions of water-miscible and can provide a furfural yield of greater than 70%. |
| US08524918B2 |
Atropisomer of pyrrole derivative
[Object] A prophylactic or therapeutic agent for a cardiovascular disease is provided.[Means for Resolution] An atropisomer of a compound represented by the following general formula (I): (wherein R1 is a C1-C3 alkyl group or a hydroxy-C1-C3 alkyl group; and R2 is a hydrogen atom or a C1-C3 alkoxy group). |
| US08524916B2 |
Dithiinetetra(thio)carboximides
The present invention relates to novel dithiinetetra(thio)carboximides, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators. |
| US08524913B2 |
Process for production of α-trifluoromethyl-β-substituted-β-amino acid
α-Trifluoromethyl-β-substituted-β-amino acids can be produced by allowing α-trifluoromethyl-β-substituted-α,β-unsaturated esters to react with hydroxylamine to convert α-trifluoromethyl-β-substituted-α,β-unsaturated esters into dehydrogenated closed-ring body of α-trifluoromethyl-β-substituted-β-amino acid, and by hydrogenolyzing the dehydrogenated closed-ring body. According to this production process, novel α-trifluoromethyl-β-substituted-β-amino acids which are free amino acids whose functional groups are not protected can be produced, in which β-position substituent is not limited to aromatic ring group or substituted aromatic ring group while the relative stereochemistry of α-position and β-position can be also controlled. |
| US08524908B2 |
Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
A process for preparing a compound of formula (I), or a pharmaceutically acceptable salt thereof, which process comprises: a) reacting, in a xylene solvent, a compound of formula (V) having P1 and P2 protecting groups, with a compound of formula (IV), to give a compound of formula (III); and b) effecting a P1 deprotection step and a P2 deprotection step to give a compound of formula (I); and optionally c) preparing a pharmaceutically acceptable salt of a compound of formula (I); wherein the compounds of formulas III, IV, and V are described in the specification. |
| US08524907B2 |
Methods of synthesizing pharmaceutical salts of a factor Xa inhibitor
Novel methods of preparing a compound of Formula I which is an inhibitor of Factor Xa and its maleate salt, are described herein. |
| US08524906B2 |
Tetrahydrothiazolopyridine inhibitors of phosphatidylinositol 3-kinase
The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. |
| US08524905B2 |
Processes for preparing 6-(difluoromethoxy)[1]benzofuro[3,2-c]pyridine-9-carbaldehyde, a novel intermediate for the synthesis of PDE IV inhibitors
The present invention relates to novel processes for preparing 6-(difluoromethoxy)[1]benzofuro[3,2-c]pyridine-9-carbaldehyde, which is a novel and useful intermediate for preparing compounds with PDE4 inhibitory activity, such as 3,5-dichloro-4-(6-difluoromethoxybenzo[4,5]furo[3,2-c]pyridin-9-ylcarboxamido)-1-pyridiniumolate. |
| US08524903B2 |
Ruthenium or osmium complexes and their uses as catalysts for water oxidation
The present invention provides ruthenium or osmium complexes and their uses as a catalyst for catalytic water oxidation. Another aspect of the invention provides an electrode and photo-electrochemical cells for electrolysis of water molecules. |
| US08524890B2 |
Water-soluble phthalocyanine dye
The invention has for its object to provide a water-soluble phthalocyanine dye unlikely to lose its own properties even upon dissolved in a concentration as high as 10−5 M.The inventive water-soluble phthalocyanine dye is characterized by having a sulfuric acid group or groups as an axial ligand or ligands of an antimony/phthalocyanine complex. The sulfuric acid group or groups have been introduced by replacing a part or the whole of hydroxyl groups in the starting material with a sulfuric acid group or groups. |
| US08524884B2 |
Outer layer material having entanglement of hydrophobic polymer hostblended with a maleated hydrophobic polymer co-host, and hydrophilic polymer guest
An outer layer material having an entanglement comprising an intermingling of cloaked hydrophilic guest and a hydrophobic polymer host, wherein molecules of the guest have been crosslinked with each other. Under certain circumstances, using complexes of the guest may be desirable or even necessary. Prior to intermingling with the guest, a host blend may be produced to include a physical blend of a hydrophobic polymer host and a maleated hydrophobic co-host (preferably, an anhydride functionalized hydrophobic polymer, whereby the polymer so functionalized, is the same as that selected for the host). The intermingling of the guest and host, or host-co-host blend, includes a physical tangling, whether it also comprises crosslinking by primary bonding (e.g., chemical/covalent bonding) there-between. Also a method of producing an outer layer material having such an entanglement, including the steps of: temporarily cloaking at least a portion of the hydrophilic groups of the guest; intermingling at least a portion of the cloaked groups with a porous polymeric structure by diffusing the guest with cloaked groups into at least a portion of the structure's pores; within the pores, crosslinking at least a portion of the molecules of the guest with the guest; and removing the cloaking. Cloaking may be performed by silylation or acylation. Intermingling may be performed by producing a mixture of guest and host, or host blend, (whether in solution, powdered, granular, etc., form); next, a crosslinking of the guest with itself is performed; then, the mixture is molded into the outer layer with or without additional crosslinking of the host to the host. |
| US08524883B2 |
Monohydrate of (1-{9-[4S,2R,3R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-aminopurin-2-yl}pyrazol-4-yl)-N-methylcarboxamide
Disclosed is a synthesis suitable for large scale manufacture of an A2A-adenosine receptor agonist, namely, (1-{9-[(4S,2R,3R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-aminopurin-2-yl}pyrazol-4-yl)-N-methylcarboxamide. Also, disclosed are polymorphs of this compound and methods for isolating a specific polymorph. Also, disclosed are pharmaceutical compositions and methods for preparing pharmaceutical compositions. |
| US08524881B2 |
Reduction of off-target RNA interference toxicity
The present invention is directed to RNA interference (RNAi) molecules targeted against a nucleic acid sequence, and methods of using these RNAi molecules to reduce off-target toxicity. |
| US08524878B1 |
Methods of identifying an organism
This disclosure features methods of identifying an organism. In certain embodiments, the invention provides methods of distinguishing virulent and non-virulent strains of Listeria monocytogenes. |
| US08524877B2 |
Oligonucleotide sequence formula for labeling oligonucleotide probes and proteins for in-situ analysis
The present invention provides oligonucleotide probes and oligonucleotide probe collections for detecting or localizing a plurality nucleic acid target genes within a cell or tissue sample. Specifically, the invention provides collections of oligonucleotide probes for use in in situ hybridization analyses in which each probe has a label-domain with the sequence formulas of (CTATTTT)nCT, (AAAATAG)n or (TTTTATC)n or (GATAAAA)n in which all cases “n” would equal 1 or greater. The present invention also provides collections or “cocktails” of oligonucleotide probes for detecting or localizing specific nucleic acid target genes within a cell or tissue sample. |
| US08524872B2 |
Nucleic acids and corresponding proteins entitled 158P3D2 useful in treatment and detection of cancer
A novel gene 158P3D2 and its encoded protein, and variants thereof, are described wherein 158P3D2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 158P3D2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 158P3D2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 158P3D2 can be used in active or passive immunization. |
| US08524871B2 |
Modified gherlin peptides
The present invention provides a peptide-type compound which induces secretion of growth hormone and which has the activity of increasing the intracellular calcium ion concentration, wherein at least one amino acid is replaced by a modified amino acid and/or a non-amino acid compound, or a pharmaceutically acceptable salt thereof. |
| US08524865B2 |
Antibodies and immunoconjugates and uses therefor
Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided. |
| US08524857B2 |
Diamino-alcohol compounds, their manufacture and use in epoxy resins
A new class of compounds, namely diamino alcohols, is described, along with a process for their production and their use as hardeners, or curing agents, for epoxy resin systems, some of which have high glass transition temperatures, Tgs, such as greater than about 120° C. |
| US08524849B2 |
Hydrophilic organofunctional silicone copolymers
Hydrophilic silicone copolymers are the addition polymerization product of an unsaturated silicone macromer, and unsaturated polyoxyalkylene polyether, and optionally further unsaturated addition polymerizable monomers. |
| US08524848B2 |
Curable silicone gel composition
A curable silicone gel composition that is of low viscosity, exhibits good fluidity, and generates a silicone gel that exhibits good resistance to external stress and thermal stress. The composition includes (A) a specific organopolysiloxane having at least two alkenyl groups within each molecule, (B) an organohydrogenpolysiloxane having a specific branched main chain structure, containing at least three SiH groups within each molecule, and also containing at least one branch-forming unit within each molecule, and (C) a platinum-based catalyst, wherein the cured product has a penetration value of 10 to 200, and loss coefficient values at 25° C. for shear frequency values of 1 Hz and 10 Hz of 0.1 to 1.0 and 0.3 to 1.5 respectively. |
| US08524845B2 |
Catalyst composition and a process for the oligomerization of ethylene
The present invention relates to a catalyst composition for the oligomerization of ethylene comprising at least one transition metal bisphenolate compound and at least one cocatalyst. The transition metal bisphenolate is a zirconium bisphenolate.The invention also relates to a process for the oligomerization of ethylene in the presence of the catalyst composition according to the invention. The process results in a high yield of C4-C18 linear alpha-olefin and C6-C10 linear alpha-olefin. |
| US08524843B2 |
Production of highly reactive low molecular weight PIB oligomers
In an embodiment, the present invention provides a process for the liquid phase polymerization of isobutylene to manufacture highly reactive PIB oligomers having Mn under 1000, using a catalyst composition comprising a Friedel-Crafts catalyst and a complexing agent, in the presence of a chain transfer agent. The process advantageously uses short residence times for the isobutylene in the polymerization reaction zone as well as a chain transfer agent selected from: α-DIB and β-DIB and mixtures thereof. |
| US08524842B2 |
Silicone compositions crosslinkable into adhesive gels
Gels having viscoelastic qualities, physical stability and adhesive properties, well suited for a wide variety of end applications, are prepared by crosslinking, by hydrosilylation, silicone compositions which contain: a polyorganosiloxanes POS (I) of SiH type; a polyorganosiloxanes POS (II) of SiVi type (Vi=vinyl); a polyorganosiloxanes POS (III) of monofunctional SiVi type; a platinum-based catalyst (D); and optionally, a polyorganosiloxanes POS (IV) of polydimethylsiloxane type. |
| US08524838B2 |
Heat-curable urethane resin composition
The invention provides a heat-curable resin composition comprising (A) a polyurethane having two or more carboxyl groups in one molecule, in particular a polyurethane having one or more carboxyl groups at a molecular terminal and (B) a heat-curable component, a cured product thereof, a solder resist and a protective film consisting of the cured product and a printed wiring board coated with the cured product. The polyurethane (A), preferably has a number average molecular weight of 500 to 100,000 and an acid value of 5 to 150 mgKOH/g. The heat-curable component (B) is preferably an epoxy resin. The heat-curable resin composition of the invention is excellent in adhesion with a substrate, low-warpage property, flexibility, resistance to moisture and heat, soldering heat resistance and resistance to tin plating. |
| US08524837B2 |
Heat-curing powder-lacquer compositions yielding a matte surface after curing of the coating, as well as a simple method for production of same
The invention relates to heat-curing powder-lacquer compositions exhibiting a matte surface after curing of the coating, as well as to a simple method for production of the same. |
| US08524836B2 |
Crosslinkable acrylate adhesive polymer composition
A pre-adhesive syrup copolymer composition comprising an acid functional acrylate solute copolymer, a monomer solvent mixture, and a polyaziridine crosslinking agent is disclosed. |
| US08524834B2 |
Coating compositions containing tetramethyl cyclobutanediol
Disclosed are solvent borne thermosetting coating compositions that contain a curable polyester resin blended with an acrylic copolymer, a crosslinker, and a solvent. The polyester resin contains 2,2,4,4-tetramethyl-1,3-cyclobutanediol and exhibits good dry time, compatibility with acrylic resins, sag resistance and hardness development in a coating composition. The coating compositions can be used to prepare clear coat or pigmented coatings for automotive OEM, auto refinish, and other applications. |
| US08524833B2 |
High-efficiency light diffusing polymeric film and manufacturing method thereof
A high-efficiency light diffusing polymeric film comprises a first polymer which is a light transmissible medium, and a second polymer which forms light scattering particles, wherein the polymers are immiscible and have a refractive index difference of about 0.001 to about 0.5, and the polymeric film comprises about 30 about to 70 parts by weight of the second polymer with respect to 100 parts by weight of the first polymer. A method for manufacturing a high-efficiency polymeric film is carried out such that a first polymer forms a continuous phase and a second polymer forms a dispersed phase through coating or extrusion. |
| US08524832B2 |
Biodegradable impact-modified polymer compositions
The invention relates to a impact-modified bio-degradable polymer composition having large particle size impact modifiers dispersed in a continuous biodegradable polymer phase. The impact modifiers have a core-shell morphology and have average sizes of greater than 250 nm. The impact-modified composition has good impact properties and low haze. The biodegradable polymer is preferably a polylactide or polyhydroxy butyrate. The composition comprises 30-99.9 weight percent of degradable polymer and 0.1 to 15 weight percent of one or more impact modifiers. |
| US08524830B2 |
Resin composition and resin molded product
A resin composition includes a polyester capable of forming a crystal structure, and a substance represented by the following general structural formula (1), the substance represented by the following general structural formula (1) has a dehydration-condensed structure of two molecules of natural product-derived α-amino acids or a substitution structure thereof, and the two molecules of α-amino acids are not simultaneously glycine. In the above general structural formula, R1, R2, R3, and R4 indicate groups or substituent groups thereof bonded to the α carbons of the α-amino acids. |
| US08524828B2 |
Polymeric compositions
A one or two part organopolysiloxane composition capable of cure to an elastomeric body, the composition comprising a polymer having a polymer backbone selected from an organopolysiloxane backbone and a telechelic backbone, which polymer has not less than two reactable silicon-bonded groups selected from alkenyl group, condensable groups, silyl-hydride groups, 5 to 50% by weight of the composition of an extender; a suitable cure catalyst; and optionally a siloxane and/or silane cross-linker having at least two groups per molecule which are reactable with the reactable groups in (a) and/or one or more fillers. The extender is selected from an alicyclic ester having at least two ester groups, and a boiling point of at least 180° C. or a mixture thereof having a boiling point range commencing at 180° C. or above; each ester group being the same or different and comprising from 2 to 30 carbon atoms. |
| US08524819B2 |
Thermoplastic polymer composition and production method thereof
A thermoplastic polymer composition comprising a thermoplastic polymer, a compound of the formula (1): (wherein, R1 and R2 represent each independently an alkyl group having 1 to 8 carbon atoms, an aryl group having 6 to 12 carbon atoms or an aralkyl group having 7 to 18 carbon atoms, R3 represents an alkyl group having 1 to 3 carbon atoms, and R4 represents a hydrogen atom or methyl group), and a hydrocarbon, wherein 0.001 to 3 parts by weight of the compound of the formula (1) and 0.0005 to 0.008 parts by weight of the hydrocarbon are contained with respect to 100 parts by weight of the thermoplastic polymer. |
| US08524818B2 |
Thermoplastic composition
The invention relates to a composition containing a particulate solid, a plastic material (such as a thermoplastic polymer) and a compound containing an amide group. The compound is capable of being a dispersant. The invention further relates to novel compounds, and the use of the compound as a dispersant. |
| US08524816B2 |
Coating resistant to bio-diesel fuels
One embodiment of the invention includes a product including a coating comprising (a) a primary resin and a blocked isocyanate, and (b) at least one bio-diesel fuel degradation product neutralizing material. |
| US08524811B2 |
Algae-blended compositions for thermoplastic articles
A thermoplastic material composition containing certain biodegradable and renewable components is described. The thermoplastic composition that includes a least one kind of algae or a blend of at least one kind of algae and a plant polymer a blend of algae and/or plant-based polymers, such as proteins and starches, as relatively low cost feedstock. The algae or blend may be plasticized. Additionally, a method adapted for large scale fabrication of fibers, films, or extruded articles is also described. |
| US08524803B2 |
Encapsulation product, process for producing the same, and ink composition
An encapsulated product comprising a core substance encapsulated with a wall material mainly comprising a polymer, wherein the polymer contacts the core substance through an ionic surfactant a and comprises at least (1) a repeating structural unit derived from an ionic polymerizable surfactant B and/or ionic monomer and (2) a repeating structural unit derived from an ionic polymerizable surfactant C having an electric charge the same as or opposite the electric charge of the ionic surfactant; or an encapsulated product comprising a core substance with a wall material mainly comprising a polymer, wherein the polymer comprises a repeating structural unit comprising a hydrophobic monomer and is present between (1) an ionic surfactant b and (2) an ionic surfactant c. |
| US08524798B2 |
Materials and apparatus for in-situ bone repair
Compositions for use in treating and repairing orthopedic defects are provided. The compositions are especially useful for performing percutaneous vertebroplasty, percutaneous kyphoplasty and other procedures. When cured, the compositions are relatively solid but compressible, and prior to curing are viscous liquids with a low enough viscosity to fill voids in cavities such as voids within fractured vertebrae. Optionally, the properties of a composition according to the invention can be adjusted taking into account the hardness and density of the orthopedic structure to be repaired. Also disclosed are devices and methods for using the compositions, and a kit containing components for forming and utilizing the composition. |
| US08524792B2 |
Deformable, rigid polystyrene foam board
Provided are methods for producing a high strength, but easily deformed, polystyrene foam board that can endure repeated deformations from its original configuration into more complex curved shapes without damaging the board integrity or substantially reducing its structural strength. Also provided are rigid polystyrene foam boards produced by this method that exhibit improved bending and impact resistance while substantially retaining or improving other properties, for example, the thermal dimensional stability and fire resistance, exhibited by corresponding conventional XPS foam boards. The foamable compositions may incorporate one or more of a variety of polymer processing aids for the purpose of altering the performance of the final foam products, thereby allowing the properties of the final foam product to be customized to some degree. |
| US08524791B2 |
Process for the preparation of flexible, resilient polyurethane foam and the resulting foam
The flexible, resilient polyurethane foam is prepared by reacting at least one polyisocyanate with one or more liquid compounds which have at least two isocyanate reactive groups and at least one of which contain one or more solid polymers stably dispersed therein in an amount of 2.5 to 35 parts per 100 parts of said liquid isocyanate reactive groups containing compounds. The wet compression set of the flexible polyurethane foam could be considerably reduced by including in said liquid isocyanate reactive groups containing compounds, per 100 parts thereof, (I) 50 to 80 parts of one or more polyoxyalkylene polyols having an oxyethylene unit content of at least 40 wt. %, a hydroxyl number of between 20 and 100, and a nominal functionality of 2 to 4; and (II) 20 to 50 parts of one or more further polyoxyalkylene polyols containing no oxyethylene units or having an oxyethylene unit content lower than 40 wt. %, and having a hydroxyl number of between 20 and 100 and a nominal functionality of 2 to 4. |
| US08524781B2 |
Organosulfur compounds, a method of making organosulfur compounds and their use for inhibiting the growth of tumour cells
Organosulfur compounds of the general formula (2) are described, wherein R1 and R2 are linear or branched C1-C5 alkyl; linear or branched C1-C5 alkenyl with the proviso that R1 is not prop-1-enyl (allyl); substituted linear or branched C1-C5 alkenyl or substituted linear or branched C1-C5 alkyl, in which the substituents are selected from OR3, NR4R5, COOR6, CON—R7R8, in which R3 is selected from H, COR9, para-methoxybenzyl and trialkylsilyl, in which R9 is alkyl or substituted alkyl; R4 N and R5 are alkyl or R4 and R5 together form a phthalimido group; R6 is alkyl or substituted alkyl; and R7 and R8 are alkyl or substituted alkyl; substituted or unsubstituted aromatic specifically where R1 and R2 are benzyl, para-methoxybenzyl and/or ortho,para-methoxybenzyl and substituted or unsubstituted heteroaromatic. The compounds can be used for inhibiting the growth of tumor cells and for treating cancer. A pharmaceutical composition and a method of preparing the compounds are also described. |
| US08524780B2 |
Deuterium-enriched bupropion
The present application describes deuterium-enriched bupropion, pharmaceutically acceptable salt forms thereof, and methods of treating using the same. |
| US08524770B2 |
Wool care composition
The present invention relates to a wool care composition comprising pyrethroid insecticide, a copolymer and a solvent wherein the said copolymer binds with the solvent and pyrethroid insecticide. This composition can be an improved aerosol spray formulation for treating of pure or blended woollen clothing and textile, fur and feather lined garments and other keratinous items for protection or insect proofing from various types of insect pests both clothes moths and carpet beetles during their storage, transport and use. Wool care aerosol solution can be sprayed with pressurized container having either a propellant as ready-to-use aerosol or manually operated sprayers. The aerosol spray composition may also contain fragrance and solvent. The other components in the composition are at least one copolymer/emulsifier and/or dispersant. |
| US08524769B2 |
Process for producing a fraction enriched up to 100% of 3-O-acetyl-11-keto-beta-boswellic acid from an extract containing a mixture of boswellic acids
The invention relates to a process for producing a fraction enriched upto 100% of 3-O-acetyl-11-keto-β-boswellic acid. An organic solvent extract of gum resin from Boswellia species is first subjected to oxidation and then acetylation or vice versa. This converts the less potent boswellic acids present in the fraction to AKBA. This treated fraction is subjected to further purification and separation by chromatographic separation techniques to enhance its purity and to remove contaminants therefrom. This process provide an access to a fraction enriched in 10-100% AKBA for therapeutic applications. |
| US08524768B2 |
Antioxidants for preventing and treating diseases caused by oxidative stress
Antioxidant compositions for the treatment and prophylaxis of illnesses associated with oxidative stress and lack of oxygen in the human body, comprising a complex of a metal selected from the group consisting of iron, copper, zinc and manganese with rutin and ascorbic acid and/or dihydroascorbic acid. Methods for synthesizing the antioxidant compositions and granulates, tablets and capsules containing antioxidant compositions are also provided. |
| US08524760B2 |
HCV protease inhibitors and uses thereof
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. |
| US08524757B2 |
Benzimidazole cannabinoid agonists bearing a substituted heterocyclic group
The present invention is related to novel benzimidazole compounds of formula (I) having cannabinoid receptor agonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals, in particular humans. |
| US08524753B2 |
Compounds that are useful for improving pharmacokinetics
Novel compounds of formula 1 or a pharmaceutically acceptable salt thereof inhibit cytochrome P450 monooxygenase. |
| US08524752B2 |
Thiazolidin-4-one derivatives
The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents. |
| US08524751B2 |
4-oxadiazol-2-YL-indazoles as inhibitors of P13 kinases
The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity. |
| US08524746B2 |
Dosage regimen for COMT inhibitors
The invention relates to the use of an oxodiazolyl compound (I) for the preparation of a medicament for the prevention or treatment of central and peripheral nervous system associated disorders, wherein said medicament is administered according to a dosing regimen having a dosing periodicity ranging from about twice a day to about once every other day. |
| US08524742B2 |
Use of 5H-thioeno(3,4-c)pyrrole-4,6-dione derivatives as tumor necrosis factor inhibitor
A method of treating or curing a disease caused by or associated with elevated levels of TNF in a patient including administering to the patient 5H-thioeno(3,4-c)pyrrole-4,6-dione derivatives. |
| US08524740B2 |
Synthesis and anticancer activity of aryl and heteroaryl-quinolin derivatives
A compound of Formula I is disclosed as follows: or a pharmaceutically acceptable salt, prodrug, solvate, or metabolite thereof, wherein R is hydrogen, P(═O)(OH)2, P(═O)(O(C1-C18)alkylene(C6-C20)aryl)2, P(═O)(OH)(OM), P(═O)(OM)2, P═O(O2M), S(═O)(OH)2, S(═O)(O(C1-C18)alkylene(C6-C20)aryl)2, S(═O)(OH)(OM), S(═O)(OM)2; M is a monovalent or divalent metal ion, or alkylammonium ion; W is (C6-C20)aryl, (C6-C20)heteroaryl, (C1-C18)alkyl(C6-C20)aryl, (C1-C18)alkyl(C6-C20)heteroaryl, hydroxy(C6-C20)aryl, hydroxy(C6-C20)heteroaryl, (C1-C18)alkoxy(C6-C20)aryl, (C1-C18)alkoxy(C6-C20)heteroaryl, (C1-C18)alkylenedioxy(C6-C20)aryl, (C1-C18)alkylenedioxy(C6-C20)heteroaryl, halo(C6-C20)aryl, halo(C6-C20)heteroaryl, (C1-C18)alkylamino(C6-C20)aryl, (C1-C18)alkylamino(C6-C20)heteroaryl, (C1-C18)cycloalkylamino(C6-C20)aryl, or (C1-C18)cycloalkylamino(C6-C20)heteroaryl, and their OR8 substutes; R5 is (C1-C18alkoxy, hydrogen, hydroxyl, O—(C1-C18)alkyl(C6-C20)aryl, halo or OR8, or R5 and R6 are (C1-C18)dioxy provided that R7 is hydrogen; R6 is hydroxyl, O—(C1-C18)alkyl(C6-C20)aryl, halo or OR8, (C1-C18)alkoxy, (C1-C18)alkylamino, or (C1-C18)cycloalkylamino, or R6 and R7 are (C1-C18)dioxy provided that R5 is hydrogen; R7 is hydrogen, halo or OR8, hydroxyl, or O—(C1-C18)alkyl(C6-C20)aryl; and R8 is P(═O)(OH)2, P(═O)(O(C1-C18)alkyl(C6-C20)aryl)2, P(═O)(OH)(OM), or P(═O)(OM)2, P═O(O2M). |
| US08524737B2 |
Bi- and polycyclic substituted isoquinoline and isoquinolinone derivatives
The invention relates to bi- and polycyclic substituted isoquinoline and isoquinolinones of the formula (I) wherein R1 to R12 are as defined in the application useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds. |
| US08524736B2 |
Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
The subject invention provides stereoisomeric compounds of formula (X): wherein the variables are as defined herein, and compositions for the safe and effective treatment of various gastrointestinal disorders including, but not limited to, gastroparesis, gastroesophageal reflux and related conditions. The compounds of the subject invention are also useful in treating a variety of conditions involving the central nervous system. |
| US08524733B2 |
Benzoquinoline inhibitors of vesicular monoamine transporter 2
The present invention relates to new benzoquinoline inhibitors of vesicular monoamine transporter 2 (VMAT2), pharmaceutical compositions thereof, and methods of use thereof. |
| US08524732B2 |
Substituted tetrahydroquinolines
Compounds of the formula (I), in which R1, R2, R3, R4, R5, X, Y, W, Q1, Q2, Z, s and m have the meanings indicated in Claim 1, can be employed, inter alia, for the treatment of tumors. |
| US08524729B2 |
Cinnamoyl derivatives and use thereof
The present invention relates to a cinnamoyl compound represented by the formula (I): |
| US08524728B2 |
Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase
This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, X and Y have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine. |
| US08524727B2 |
Pyrimidine compound
A novel and excellent method for preventing and/or treating diseases related to a cannabinoid type 2 receptor, based on an agonistic action on a cannabinoid type 2 receptor. It was found that a hetero ring derivative mainly having two substituents, for example, a pyrimidine-5-carboxamide derivative having a substituent amino group at the 2-position, exhibits a potent agonistic action on a cannabinoid type 2 receptor, and can be an agent for preventing and/or treating diseases related to a cannabinoid type 2 receptor such as inflammatory diseases, pain, and the like. |
| US08524721B2 |
Platelet ADP receptor inhibitors
Novel compounds of formulae (I) and (VIII), which more particularly include sulfonylurea derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives, sulfonylcyanoguanidine derivatives, thioacylsulfonamide derivatives, and acylsulfonamide derivatives which are effective platelet ADP receptor inhibitors. These derivatives may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of cardiovascular diseases, particularly those diseases related to thrombosis. The invention also relates to a method for preventing or treating thrombosis in a mammal comprising the step of administering a therapeutically effective amount of a compound of formulae (I) to (VIII), or a pharmaceutically acceptable salt thereof. |
| US08524718B2 |
Heteroaromatic derivatives and their use as positive allosteric modulators of metabotropic glutamate receptors
The present invention relates to novel compounds of Formula (I), wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4, M1, M2, M3, Am and Bn are defined as in Formula (I); invention compounds are modulators of metabotropic glutamate receptors—subtype 4 (“mGluR4”) which are useful for the treatment or prevention of central nervous system disorders as well as other disorders modulated by mGluR4 receptors. The invention is also directed to pharmaceutical compositions and the use of such compounds in the manufacture of medicaments, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR4 is involved. |
| US08524715B2 |
Phenoxyacetic acid derivatives useful for treating respiratory diseases
The invention relates to substituted phenoxyacetic acids as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation. |
| US08524710B2 |
Pyrrolidine derivatives
The invention relates to a compound of formula (I) wherein A1 to A4 and R1 to R6 are defined as in the description and in the claims. The compound of formula (I) can be used, for example, as inhibitors of the cysteine protease cathepsin. |
| US08524707B2 |
Bicyclic pyrazoles as protein kinase inhibitors
3,4-diaryl-bicyclicpyrazole derivatives of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer. |
| US08524701B2 |
Use of a specific cyclic amine derivative or the pharmaceutically acceptable salts thereof for the treatment or prevention of heart failure
The present invention provides the use in a pharmaceutical composition of a specific cyclic amine derivative, or its pharmaceutically acceptable salts, for the treatment of heart failure of any aetiology. |
| US08524698B2 |
Methods of treating hypertriglyceridemia
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof. |
| US08524697B2 |
C20-C21 substituted glucocorticoid receptor agonists
The present invention provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, esters, prodrugs, tautomers, or isomers of said compounds), having the general structure: wherein L, R1, R2, R3, R4, R5, and R6 are selected independently of each other and as defined herein. The present invention also provides compounds (and salts, solvates, esters, prodrugs, tautomers, and isomers) of Formulas II, III, IV, V, and VI, as defined herein. Also provided are pharmaceutical compositions, methods of preparing, and methods of using such compounds in the treatment and prophylaxis of a wide range of immune, autoimmune, and inflammatory diseases and conditions. |
| US08524693B2 |
Process for obtaining 17-spirolactones in steroids
The invention relates to processes for obtaining steroids with a spirolactone group in position 17, particularly to industrially obtaining 6β,7β; 15β,16β-dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone, commonly known as Drospirenone, as well as to intermediates useful in said process. |
| US08524692B2 |
Ocular compositions containing dioleoylphosphatidylglycerol and uses thereof
The present invention provides a method of treating a corneal disorder comprising administering to a patient in need thereof a composition containing pharmaceutically effective amount of dioleoylphosphatidylglycerol and/or palmitoyloleoylphosphatidylglycerol and a pharmaceutically acceptable carrier. |
| US08524687B2 |
Ophthalmic pharmaceutical compositions based on amino acids and sodium hyaluronate
This invention relates to ophthalmic wound-healing pharmaceutical compositions based on amino acids and sodium hyaluronate. |
| US08524686B2 |
Composition for prevention or treatment of eye diseases
Provided is a composition for prophylaxis or treatment of an eye disease comprising a compound represented by General Formula I: S-(MS)p-(MS)q General Formula I wherein S represents sialic acid, and (MS)p and (MS)q independently represent a monosaccharide residue. The compound used as the active ingredient inhibits expression of MMP-9 and inflammation-mediated cytokines (IL-1β, TNF-α, etc.) in corneal epithelial cells and inhibits VEGF-mediated VEGFR-2 activation in human retinal endothelial cells (HREC), thereby exhibiting prophylactic or therapeutic activity for eye diseases such as dry eye syndrome, inflammatory eye disease, neovascularization-associated eye disease and side effects of wearing of contact lenses. Also, because it has no cytotoxicity or skin side effect, the provided composition may be safely used as a pharmaceutical composition, a neutraceutical composition or a food composition. In addition, the composition may be used as a cleaner or a lubricant for contact lenses since it has nonbacterial antiinflammatory activity and ocular contact lubricating activity. |
| US08524683B2 |
Method for decreasing cardiac using a nucleic acid molecule encoding a variant phosphatase inhibitor-1
The present invention relates to novel nucleic acids which encode novel mutant forms of Inhibitor Protein-1 (I-1). In particular, the I-1 mutant forms comprise altered phosphorylation sites of PKC-α. In addition, the present invention relates to methods of regulating cardiac contractility and function, and for treatment of cardio myopathy and heart failure, which employ the novel nucleic acids and polypeptides. Vectors comprising the novel nucleic acids, Antibodies to the novel proteins, and diagnostic and screening methods associated therewith, are also provided. |
| US08524678B2 |
Method for delivering genes
Methods of delivering transgenes to target cells using plasmids comprising viral inverted terminal repeat (ITR) sequences are described. Such plasmids are capable of directing sustained transgene expression in target cells in rats provided that at least one adeno-associated virus (AAV) ITR sequence is present in the plasmid, regardless of whether that ITR is located upstream or downstream of the transgene. In a particular embodiment, plasmids comprising one or more AAV ITR sequence and an IL-10 transgene are shown to be effective in sustained reversal of pain in an animal model of neuropathic pain. |
| US08524675B2 |
Antibacterial aminoglycoside analogs
Compounds having antibacterial activity are disclosed. The compounds have the following structure (I) or (II): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R1, R2, R3, R11 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. |
| US08524674B2 |
Method of improving the conditioned reflex habit, the muscle tonus, or the motion coordination of a patient after suffering trauma to the brain cortex
Disclosed is a method of improving the conditioned reflex habit, the muscle tonus, or the motion coordination of a patient after suffering trauma to the brain cortex that involves administering to the patient an effective amount of a composition containing peptide glutamyl-aspartyl-arginine of the formula H-Glu-Asp-Arg-OH as its active base. |
| US08524672B2 |
Method for inhibiting BAFF-R activity
Disclosed are nucleic acids encoding BAFF-R polypeptides, as well as antibodies to BAFF-R polypeptides and pharmaceutical compositions including the same. Methods of treating tumorigenic and autoimmune conditions using the nucleic acids, polypeptides, antibodies and pharmaceutical compositions of this invention are also provided. |
| US08524668B2 |
Methods of protecting against apoptosis using lipopeptides
The use of lipopeptides as inducers of NF-κB for the protection of mammals from the effects of apoptosis is described. |
| US08524664B2 |
Methods of treating overproduction of cortisol using ACTH antagonist peptides
The present invention provides methods of treating overproduction of cortisol in a subject by administering to the subject a peptide that antagonizes adrenocorticotropin hormone (ACTH) to block the activation of melanocortin 2 receptors. |
| US08524662B2 |
Compositions and methods for treating joints
Methods and compositions are disclosed for an intra-articular injection for the treatment of osteoarthritis. The methods and compositions comprising combinations of hyaluronic acid and a bone morphogenetic protein, like rhGDF-5, can be useful for any synovial joint, including the knee, shoulder, hip, ankle, hands, spinal facet, or temporomandibular joint, both for the relief of pain and for slowing disease progression. |
| US08524658B2 |
Lactoferrin and brain health and development in infants
The present invention relates generally to the field of brain development and brain health. One embodiment of the present invention relates to a composition that can be used for the treatment or prevention of a delayed brain development and/or a delayed development of the nervous system. Also cognitive performance can be increased. |
| US08524657B2 |
Peptidic compounds
The present invention provides a compound of formula I, II, III and IV as defined herein and pharmaceutically acceptable derivatives thereof. The present invention further provides use of the compounds of the present invention in the treatment of bacterial infection and in the treatment of HIV infection. Also provided are pharmaceutical compositions comprising the compounds of the present invention. |
| US08524650B2 |
Encapsulates
The present application relates to perfume compositions, delivery systems comprising such perfumes products comprising such perfumes and/or delivery systems, and processes for making and using same. Such perfumes and delivery systems provide improved perfume performance under high soil conditions and in cold water washing and a shell that at least partially surrounds said core. |
| US08524647B2 |
Method of making a composition and the uses thereof in removing or dissolving a contaminant from an environment
A composition which is effective in removing a wide variety of contaminants, such as organic compounds, from a wide variety of environments, such as printing systems, is provided. A process of preparing such composition includes contacting hydrogen peroxide, glycolic acid, and water. The process can additionally include contacting with one or more additional components such as isopropyl alcohol. |
| US08524645B2 |
Viscosity improver compositions providing improved low temperature characteristics to lubricating oil
A lubricant composition comprising an oil of lubricating viscosity; (A) 0.05 to 1.5 percent by weight of a copolymer comprising 70 to 79 percent by weight of units derived from ethylene (“E”), having a Mw of 50,000 to 100,000, Mw/ Mn less than 3, density (“D”) of 860 to 896 kg/m3, and a melting point (“Tm”) of 15° C. to 60° C., wherein E and Tm fulfill the expression 3.44E−206≧Tm; and (B) 0.05 to 1.5 percent by weight of a block copolymer comprising a first block which comprises a vinyl aromatic comonomer and a second block which comprises a diene comonomer, the diene monomer-containing block being hydrogenated; wherein the weight ratio (A):(B) is 20:80 to 60:40; exhibits good low temperature performance and durability. |
| US08524641B2 |
Aqueous foaming compositions with high tolerance to hydrocarbons
A composition for providing a stable foam with high tolerance to hydrocarbons includes (a) an aqueous liquid; (b) at least one water soluble or dispersible silicon-containing polyether foamant contained within the aqueous liquid; and (c) a non-aqueous liquid. The aqueous liquid includes water and brine. The non-aqueous liquid includes liquid hydrocarbons. |
| US08524639B2 |
Complementary surfactant compositions and methods for making and using same
Complementary surfactant systems and downhole fluids made using the systems are disclosed along with methods for making and using same, where the surfactant systems include from 0 wt. % to 100 wt. % of a first surfactant subsystem, from 100 wt. % to 0 wt. % of a second surfactant subsystem, and from 0 wt. % to 100 wt. % of a solvent subsystem based on the wt. % of the surfactant subsystems, where the system is tailored to foam the fluid including the analyzed crude and/or condensate. |
| US08524635B2 |
Antifungal composition
The present invention relates to a process for the treatment of an agricultural product which comprises the addition of a composition which comprises phosphite and natamycin to the agricultural product wherein the composition comprises preferably less than 0.1 g lignosulphonate, more preferably less than 0.1 g polyphenol, per gram natamycin and is still more preferably free of lignosulphonate and most preferably free of polyphenol. |
| US08524634B2 |
Seed treatment with combinations of pyrethrins/pyrethroids and clothianidin
A method of preventing damage to the seed and/or shoots and foliage of a plant by a pest includes treating the seed from which the plant grows with a composition that includes a combination of clothianidin and at least one pyrethrin or synthetic pyrethroid. The treatment is applied to the unsown seed. In another embodiment, the seed is a transgenic seed having at least one heterologous gene encoding for the expression of a protein having pesticidal activity against a first pest and the composition has activity against at least one second pest. Treated seeds are also provided. |
| US08524631B2 |
Nano-skeletal catalyst
A method of producing a catalyst material with nano-scale structure, the method comprising: introducing a starting powder into a nano-powder production reactor, the starting powder comprising a catalyst material; the nano-powder production reactor nano-sizing the starting powder, thereby producing a nano-powder from the starting powder, the nano-powder comprising a plurality of nano-particles, each nano-particle comprising the catalyst material; and forming a catalyst precursor material from the nano-powder, wherein the catalyst precursor material is a densified bulk porous structure comprising the catalyst material, the catalyst material having a nano-scale structure. |
| US08524627B2 |
Activating supports with controlled distribution of OH groups
The present invention relates to a process for preparing an activating support for metallocene complexes in the polymerization of olefins comprising the steps of: I) providing a support consisting in particles formed from at least one porous mineral oxide; II) optionally fixing the rate of silanols on the surface of the support; III) functionalizing the support with a solution containing a metallic salt; IV) heating the functionalized support of step c) under an inert gas or hydrogen; V) oxidizing the support of step IV by treatment under N2O and then under oxygen; VI) retrieving an active support having a controlled number of OH groups. That activating support is used to activate a metallocene catalyst component for the polymerization of olefins. |
| US08524624B2 |
Mesostructured zeolitic materials, and methods of making and using the same
One aspect of the present invention relates to mesostructured zeolites. The invention also relates to a method of preparing mesostructured zeolites, as well as using them as cracking catalysts for organic compounds and degradation catalysts for polymers. |
| US08524617B2 |
Methods for manufacturing dielectric films
A method for manufacturing a dielectric film having a high dielectric constant is provided.The method is a method for forming, on a substrate, a dielectric film including a metal oxide containing O and elements A and B, wherein the element A comprises Hf or a mixture of Hf and Zr and the element B comprises Al or Si, which includes the steps of: forming a metal oxide having an amorphous structure which has a molar ratio between element A and element B, B/(A+B) of 0.02≦(B/(A+B))≦0.095 and a molar ratio between element A and O, O/A of 1.0<(O/A)<2.0; and annealing the metal oxide having the amorphous structure at 700° C. or more to form a metal oxide containing a crystal phase with a cubic crystal content of 80% or more. |
| US08524616B2 |
Method of nonstoichiometric CVD dielectric film surface passivation for film roughness control
A method is provided for reducing film surface roughness in Chemical Vapor Deposition (CVD) of dielectric films. The method may include removing dangling bonds from a film surface of a CVD dielectric film by a reactant. For reducing a surface roughness of a dielectric film, a further method may passivate a nonstoichiometric film surface of the dielectric film, or of a previous dielectric film, or of the dielectric film and of a previous dielectric film, by a reactant gas in the vapor environment. The dielectric film may include at least one out of the following group: ultraviolet light transparent Silicon Nitride (UVSIN), Silicon Rich Oxide (SRO), Silicon Dioxide (SiO2), Silicon Nitride (Si3N4), Phosphosilicate Glass (PSG), or Silicon Oxynitride (SiON) The reactant gas may include at least one out of the following group: Ammonia (NH3), Hydrogen (H2), Nitrous Oxide (N2O), or Oxygen (O2). |
| US08524608B1 |
Method for fabricating a patterned structure of a semiconductor device
The present invention provides a method for fabricating a patterned structure in a semiconductor device, which includes the following processes. First, a target layer, a first mask and a first patterned mask are sequentially formed on a substrate. Then, a first etching process is performed to form a plurality of characteristic structures on the substrate, wherein each of the characteristic structures comprises a patterned first mask and a patterned target layer. A second patterned mask is formed on the substrate, wherein the second patterned mask covers a portion of the characteristic structures and exposes a predetermined region. A second etching process is performed to fully eliminate the characteristic structures within the predetermined region. Finally, a third etching process is performed to fully eliminate the target layer not covered by the patterned first mask. |
| US08524607B2 |
Anisotropically conductive member and method of manufacture
An anisotropically conductive member has an insulating base material, and conductive paths composed of a conductive material which pass in a mutually insulated state through the insulating base material in a thickness direction thereof and which are provided in such a way that a first end of each conductive path is exposed on a first side of the insulating base material and a second end of each conductive path is exposed on a second side of the insulating base material. The conductive paths have a density of at least 2 million paths/mm2 and the insulating base material is a structure composed of an anodized aluminum film having micropores therein. |
| US08524602B2 |
Method for forming vias in a substrate
The present invention relates to a method for forming vias in a substrate, including the following steps: (a) providing a substrate having a first surface and a second surface; (b) forming a groove on the substrate; (c) filling the groove with a conductive metal; (d) removing part of the substrate which surrounds the conductive metal, wherein the conductive metal is maintained so as to form an accommodating space between the conductive metal and the substrate; (e) forming an insulating material in the accommodating space; and (f) removing part of the second surface of the substrate to expose the conductive metal and the insulating material. In this way, thicker insulating material can be formed in the accommodating space, and the thickness of the insulating material in the accommodating space is even. |
| US08524596B2 |
Techniques for improving bond pad performance
Techniques for bond pad fabrication are provided. In one aspect, a method of forming a bond pad comprises the following steps. At least one alloying element is selectively introduced to at least a portion of at least one surface of the bond pad. The at least one alloying element is diffused into at least a portion of the bond pad through one or more thermal cycles. The at least one alloying element may be selectively introduced to the bond pad by depositing an alloying element layer comprising the at least one alloying element onto the bond pad and patterning and etching at least a portion of the layer. |
| US08524595B2 |
Semiconductor package structures
A semiconductor structure includes a plurality of solder structures between a first substrate and a second substrate. A first encapsulation material is substantially around a first one of the solder structures and a second encapsulation material is substantially around a second one of the solder structures. The first one and the second one of the solder structures are near to each other and a gap is between the first encapsulation material and the second encapsulation material. |
| US08524592B1 |
Methods of forming semiconductor devices with self-aligned contacts and low-k spacers and the resulting devices
One illustrative method disclosed herein includes removing a portion of a sacrificial sidewall spacer to thereby expose at least a portion of the sidewalls of a sacrificial gate electrode and forming a liner layer on the exposed sidewalls of the sacrificial gate electrode. In this example, the method also includes forming a sacrificial gap fill material above the liner layer, exposing and removing the sacrificial gate electrode to thereby define a gate cavity that is laterally defined by the liner layer, forming a replacement gate structure, removing the sacrificial gap fill material and forming a low-k sidewall spacer adjacent the liner layer. A device is also disclosed that includes a gate cap layer, a layer of silicon nitride or silicon oxynitride positioned on each of two upstanding portions of a gate insulation layer and a low-k sidewall spacer positioned on the layer of silicon nitride or silicon oxynitride. |
| US08524590B2 |
Memory device and method for manufacturing memory devices
Provided are a method for manufacturing a memory device and a memory device manufactured by the method. The memory device may be a flash memory device. The method for manufacturing the memory device may include sequentially stacking a tunnel dielectric, a floating gate conductive layer, an inter-gate dielectric, and a control gate conductive layer on a semiconductor substrate; anisotropically etching the floating gate conductive layer, the inter-gate dielectric, and the control gate conductive layer to form gate structures. The gate structures may be separated by regions where top surfaces of the tunnel dielectric are exposed, the exposed top surfaces being damaged during formation of the gate structures. The method includes reacting the exposed top surfaces of the tunnel dielectric damaged during the formation of the gate structures with a reaction gas comprising ammonium fluoride to form a reaction by-product on the exposed top surfaces of the tunnel dielectric, and removing the reaction by-product. |
| US08524589B2 |
Plasma treatment of silicon nitride and silicon oxynitride
A method of forming a semiconductor device is disclosed. Nitrogen layers of an IPD stack are deposited using silane and a nitrogen plasma to yield a nitride layer plasma treated through its entire thickness. In addition to nitriding the bottom nitride layer of the stack, the middle nitride layer may also be nitrided. Depositing silicon from silane in a nitrogen plasma may be accomplished using high density plasma, ALD, or remote plasma processes. Elevated temperature may be used during deposition to reduce residual hydrogen in the deposited layer. |
| US08524587B2 |
Non-uniformity reduction in semiconductor planarization
Provided is a method of planarizing a semiconductor device. The method includes providing a substrate. The method includes forming a first layer over the substrate. The method includes forming a second layer over the first layer. The first and second layers have different material compositions. The method includes forming a third layer over the second layer. The method includes performing a polishing process on the third layer until the third layer is substantially removed. The method includes performing an etch back process to remove the second layer and a portion of the first layer. Wherein an etching selectivity of the etch back process with respect to the first and second layers is approximately 1:1. |
| US08524583B2 |
Method for growing semipolar nitride
A method for growing a semipolar nitride comprises steps: forming a plurality of parallel discrete trenches on a silicon substrate, each discrete trenches having a first wall and a second wall, wherein a tilt angle is formed between the surface of the silicon substrate and the first wall; forming a buffer layer on the silicon substrate and the trenches, wherein the buffer layer on the first wall has a plurality of growing zones and a plurality of non-growing zones among the growing zones and complementary to the growing zones; forming a cover layer on the buffer layer and revealing the growing zones; and growing a semipolar nitride from the growing zones of the buffer layer and covering the cover layer. Thereby cracks caused by thermal stress between the silicon substrate and semipolar nitride are decreased and the quality of the semipolar nitride film is improved. |
| US08524580B2 |
Manufacturing method of semiconductor substrate and substrate processing apparatus
A first processing gas containing a first element and a second processing gas containing a second element are alternately supplied to a surface of a substrate placed in a processing chamber, to thereby form a first thin film, and a second processing gas and a third processing containing the first element and different from the first processing gas are alternately supplied, to thereby form a second thin film on the first thin film, having the same element component as that of the first thin film. |
| US08524574B2 |
Method for manufacturing solid-state image pickup-device
A method for manufacturing a solid-state image device which includes the steps of: forming a silicon epitaxial growth layer on a silicon substrate; forming photoelectric conversion portions, transfer gates, and a peripheral circuit portion in and/or on the silicon epitaxial growth layer and further forming a wiring layer on the silicon epitaxial growth layer; forming a split layer in the silicon substrate at a side of the silicon epitaxial growth layer; forming a support substrate on the wiring layer; peeling the silicon substrate from the split layer so as to leave a silicon layer formed of a part of the silicon substrate at a side of the support substrate; and planarizing the surface of the silicon layer. |
| US08524569B2 |
Methods of forming an isolation layer and methods of manufacturing semiconductor devices having an isolation layer
In a method of forming an isolation layer, first and second trenches are formed on a substrate. The first and the second trenches have first and second widths, respectively, and the second width is greater than the first width. A second isolation layer pattern partially fills the second trench. A first isolation layer pattern and the third isolation layer pattern are formed. The first isolation layer pattern fills the first trench, and the third isolation layer pattern is formed on the second isolation layer pattern and fills a remaining portion of the second trench. |
| US08524564B2 |
Full silicidation prevention via dual nickel deposition approach
Semiconductor devices are formed without full silicidation of the gates and with independent adjustment of silicides in the gates and source/drain regions. Embodiments include forming a gate on a substrate, forming a nitride cap on the gate, forming a source/drain region on each side of the gate, forming a first silicide in each source/drain region, removing the nitride cap subsequent to the formation of the first silicide, and forming a second silicide in the source/drain regions and in the gate, subsequent to removing the nitride cap. Embodiments include forming the first silicide by forming a first metal layer on the source/drain regions and performing a first RTA, and forming the second silicide by forming a second metal layer on the source/drain regions and on the gate and performing a second RTA. |
| US08524562B2 |
Method for reducing Fermi-Level-Pinning in a non-silicon channel MOS device
A method to reduce (avoid) Fermi Level Pinning (FLP) in high mobility semiconductor compound channel such as Ge and III-V compounds (e.g. GaAs or InGaAs) in a Metal Oxide Semiconductor (MOS) device. The method is using atomic hydrogen which passivates the interface of the high mobility semiconductor compound with the gate dielectric and further repairs defects. The methods further improve the MOS device characteristics such that a MOS device with a quantum well is created. |
| US08524559B2 |
Manufacturing method of power transistor device
The present invention provides a power transistor device including a substrate, an epitaxial layer, a dopant source layer, a doped drain region, a first insulating layer, a gate structure, a second insulating layer, a doped source region, and a metal layer. The substrate, the doped drain region, and the doped source region have a first conductive type, while the epitaxial layer has a second conductive type. The epitaxial layer is formed on the substrate and has at least one through hole through the epitaxial layer. The first insulating layer, the gate structure, and the second insulating layer are formed sequentially on the substrate in the through hole. The doped drain region and doped source region are formed in the epitaxial layer at one side of the through hole. The metal layer is formed on the epitaxial layer and extends into the through hole to contact the doped source region. |
| US08524557B1 |
Integration technique using thermal oxide select gate dielectric for select gate and replacement gate for logic
A control gate overlying a charge storage layer is formed. A thermally-grown oxygen-containing layer is formed over the control gate. A polysilicon layer is formed over the oxygen-containing layer and planarized. A first masking layer is formed defining a select gate location laterally adjacent the control gate and a second masking layer is formed defining a logic gate location. Exposed portions of the polysilicon layer are removed such that a select gate remains at the select gate location and a polysilicon portion remains at the logic gate location. A dielectric layer is formed around the select and control gates and polysilicon portion. The polysilicon portion is removed to result in an opening in the dielectric. A high-k gate dielectric and logic gate are formed in the opening. |
| US08524555B2 |
Susceptor with backside area of constant emissivity
Methods and apparatus for providing constant emissivity of the backside of susceptors are described. Provided is a method comprising: providing a susceptor in a deposition chamber, the susceptor comprising a susceptor plate and a layer comprising an oxide, a nitride, an oxynitride, or combinations thereof, the layer being stable in the presence of the reactive process gases; and locating the wafer on a support surface of the susceptor plate. The method can further comprise selectively depositing an epitaxial layer or a non-epitaxial layer on a surface of the wafer. The method can also further comprise selectively etching to maintain the oxide, nitride, oxynitride, or combinations thereof layer. |
| US08524554B2 |
Semiconductor device and method for fabricating the same
A dual work function semiconductor device and method for fabricating the same are disclosed. In one aspect, a device includes a first and second transistor on a first and second substrate region. The first and second transistors include a first gate stack having a first work function and a second gate stack having a second work function respectively. The first and second gate stack each include a host dielectric, a gate electrode comprising a metal layer, and a second dielectric capping layer therebetween. The second gate stack further has a first dielectric capping layer between the host dielectric and metal layer. The metal layer is selected to determine the first work function. The first dielectric capping layer is selected to determine the second work function. |
| US08524553B2 |
Integrated circuit modification using well implants
A technique for and structures for camouflaging an integrated circuit structure. The integrated circuit structure is formed having a well of a first conductivity type under the gate region being disposed adjacent to active regions of a first conductivity type. The well forming an electrical path between the active regions regardless of any reasonable voltage applied to the integrated circuit structure. |
| US08524546B2 |
Formation of multi-height MUGFET
A method and structure comprise a field effect transistor structure that includes a first rectangular fin structure and a second rectangular fin structure, both positioned on a substrate. The sides of the second rectangular fin structure are parallel to the sides of the first rectangular fin structure. Further, a trench insulator is positioned on the substrate and positioned between a side of the first rectangular fin structure and a side of the second rectangular fin structure. A gate conductor is positioned on the trench insulator, positioned over the sides and the top of the first rectangular fin structure, and positioned over the sides and the top of the second rectangular fin structure. The gate conductor runs perpendicular to the sides of the first rectangular fin structure and the sides of the second rectangular fin structure. Also, a gate insulator is positioned between the gate conductor and the first rectangular fin structure and between the gate conductor and the second rectangular fin structure. The gate conductor is positioned adjacent to a relatively larger portion of the sides of the second rectangular fin structure and is positioned adjacent to a relatively smaller portion of the sides of the first rectangular fin structure. |
| US08524544B2 |
MOSFET with a nanowire channel and fully silicided (FUSI) wrapped around gate
Nanowire-channel metal oxide semiconductor field effect transistors (MOSFETs) and techniques for the fabrication thereof are provided. In one aspect, a MOSFET includes a nanowire channel; a fully silicided gate surrounding the nanowire channel; and a raised source and drain connected by the nanowire channel. A method of fabricating a MOSFET is also provided. |
| US08524543B2 |
Thyristor-based memory cells, devices and systems including the same and methods for forming the same
Semiconductor devices including a plurality of thyristor-based memory cells, each having a cell size of 4F2, and methods for forming the same are provided. The thyristor-based memory cells each include a thyristor having vertically superposed regions of alternating dopant types, and a control gate. The control gate may be electrically coupled with one or more of the thyristors and may be operably coupled to a voltage source. The thyristor-based memory cells may be formed in an array on a conductive strap, which may function as a cathode or a data line. A system may be formed by integrating the semiconductor devices with one or more memory access devices or conventional logic devices, such as a complementary metal-oxide-semiconductor (CMOS) device. |
| US08524538B2 |
Integrated circuit packaging system with film assistance mold and method of manufacture thereof
A method of manufacture of an integrated circuit packaging system includes: providing a substrate; mounting an integrated circuit over the substrate, the integrated circuit having an inactive side and a non-horizontal side; mounting a mold chase having a buffer layer over the integrated circuit; forming an encapsulation between the substrate and the buffer; and removing the mold chase, leaving the encapsulation having a recess exposing a portion of the non-horizontal side. |
| US08524531B2 |
System and method for improving solder joint reliability in an integrated circuit package
Solder joint reliability in an integrated circuit package is improved. Each terminal of a quad, flat, non-leaded integrated circuit package is formed having portions that define a solder slot in the bottom surface of the terminal. An external surface of the die pad of the integrated circuit package is also formed having portions that define a plurality of solder slots on the periphery of the die pad. When solder is applied to the die pad and to the terminals, the solder that fills the solder slots increases the solder joint reliability of the integrated circuit package. |
| US08524529B2 |
Brace for wire bond
An electrical connection includes a first wire having one end stitch bonded to a surface, such as the lead finger of a lead frame or the connection pad of a substrate. A second wire has a first end attached to the surface on a first side of the first wire and a second end attached to the surface on a second, opposing side of the first wire. The second wire acts as a brace that prevents the first wire from lifting off of the surface. If necessary, a third wire can be added that, like the second wire, acts as a brace to prevent the first wire from lifting off of the surface. |
| US08524526B1 |
Organic light emitting diode with transparent electrode and method of making same
A transparent electrode is provided for an organic light emitting diode (OLED) device. In certain embodiments, the electrode is made by sputter-depositing first and second transparent conductive oxide (TCO) layers of the same material (e.g., ITO), but with different stoichiometries, on a substrate. The first TCO layer is more oxided than is the second TCO layer. The TCO layers of the electrode on the substrate may then be heat treated (HT) at high temperature(s) in order to increase the work function (WF) and/or increase visible transmission of the electrode. The electrode is provided in an OLED device. |
| US08524524B2 |
Methods for forming back contact electrodes for cadmium telluride photovoltaic cells
A method for forming a back contact for a photovoltaic cell that includes at least one semiconductor layer is provided. The method includes applying a continuous film of a chemically active material on a surface of the semiconductor layer and activating the chemically active material such that the activated material etches the surface of the semiconductor layer. The method further includes removing the continuous film of the activated material from the photovoltaic cell and depositing a metal contact layer on the etched surface of the semiconductor layer. |
| US08524521B2 |
Method for making wafer level image module
A wafer level image module includes a photo sensor for outputting an electrical signal upon receiving light, a lens set for focusing incident light onto the photo sensor, and an adjustment member disposed between the photo sensor and the lens set for controlling the distance between the photo sensor and the lens set to compensate the focus offset of the photo sensor for enabling the lens set to accurately focus the incident light onto the photo sensor in an in-focus manner so as to provide a high image quality. |
| US08524520B2 |
Method for producing a structure comprising a mobile element by means of a heterogeneous sacrificial layer
First and second sacrificial materials are deposited on a substrate. The first and second patterns are respectively formed in the first and second sacrificial materials. The first pattern made from the first sacrificial material is arranged on the second pattern made from a second sacrificial material. The first pattern leaves an area of predefined width free on the periphery of a top surface of the second pattern. The active layer covers at least the whole of the side walls of the first and second patterns and said predefined area of the second pattern. The active area is patterned so as to allow access to the first sacrificial material. The first and second sacrificial materials are selectively removed forming a mobile structure comprising a free area secured to the substrate by a securing area. |
| US08524517B2 |
Copper blend I-VII compound semiconductor light-emitting devices
Implementations and techniques for semiconductor light-emitting devices including one or more copper blend I-VII compound semiconductor material barrier layers are generally disclosed. |
| US08524516B2 |
Liquid crystal display device and fabricating and driving method thereof
A liquid crystal display device includes a liquid crystal panel divided into a non-display area and a display area where pixel cells are arranged in a matrix, a backlight for supplying light to the liquid crystal panel, and a photo-sensing device in the non-display area for sensing an external light to control light output from the backlight in accordance with the sensed the external light. |
| US08524514B2 |
Method for producing a non-plane element
This method for producing a non-plane comprises fitting a flexible component onto a carrier by means of hybridization columns, each column having a first height and including a volume of solder material formed between two surfaces wettable by said solder material added to the flexible component and to the carrier respectively, said wettable surfaces being surrounded by zones non-wettable by the solder material, the wettable surfaces and the volume of solder material being determined as a function of a second height required for the flexible component relative to the carrier at the place where the column is formed, such that the column varies from the first height to the second height when the volume of material is brought to a temperature higher than or equal to its melting point and heating the volumes of solder material of the columns to a temperature higher than or equal to the melting point of said material in order to melt it. |
| US08524513B2 |
Measuring floating body voltage in silicon-on-insulator (SOI) metal-oxide-semiconductor-field-effect-transistor (MOSFET)
In one embodiment, a body region of a body-contacted silicon-on-insulator (SOI) metal-oxide-semiconductor-field-effect-transistor (MOSFET) is connected to a gate of another MOSFET in a sensing circuit to form a floating body node. The voltage at the floating body node is accurately obtained at the output of the sensing circuit and used to provide an estimate of required floating body voltage over a full device operating range. |
| US08524512B2 |
Method for repairing copper diffusion barrier layers on a semiconductor solid substrate and repair kit for implementing this method
Method for repairing copper diffusion barrier layers on a semiconductor solid substrate and repair kit for implementing this method.One subject of the present invention is a method for repairing a surface of a substrate coated with a discontinuous copper diffusion barrier layer of a titanium-based material.According to the invention, this method comprises: a) the contacting of the surface with a suspension containing copper or copper alloy nanoparticles for a time of between 1 s and 15 min; and b) the contacting of the thus treated surface with a liquid solution having a pH of between 8.5 and 12 and containing: at least one metal salt, at least one reducing agent, at least one stabilizer at a temperature of between 50° C. and 90° C., preferably between 60° C. and 80° C., for a time of between 30 s and 10 min, preferably between 1 min and 5 min, in order to thus form a metallic film having a thickness of at least 50 nanometers re-establishing the continuity of the copper diffusion barrier layer. |
| US08524511B1 |
Method to connect a magnetic device to a CMOS transistor
A CMOS device is provided in a substrate. A magnetic tunnel junction (MTJ) is provided over the CMOS device and connected to the CMOS device by a metal ring contact wherein a dielectric or other filling material forms the center of the metal ring contact and wherein a bottom of the metal ring contact underlying said filling material is metal. |
| US08524510B2 |
Method for manufacturing magnetic memory chip device
A method for manufacturing a magnetic memory chip device comprises the steps of: writing information in each of a plurality of magnetic memory chips formed on a silicon wafer; adhering a high magnetic permeability plate on a back face of the silicon wafer after writing information, the high magnetic permeability plate having a higher magnetic permeability than silicon and having a thickness of 50 um or more; dicing the silicon wafer into respective magnetic memory chips after adhering the high magnetic permeability plate. |
| US08524505B2 |
Blood analyzer and blood analyzing method
The present invention provides a blood analyzer and a blood analyzing method capable of obtaining information regarding B lymphocytes and T lymphocytes without using a fluorescence-labeled antibody. The blood analyzer of the present invention includes a blood specimen supplying portion, a sample preparation portion that prepares a measurement sample without using a fluorescence-labeled antibody by mixing a blood specimen supplied from the blood specimen supplying portion, a hemolyzing agent, and a fluorescent dye that stains nucleic acid, a light source, a first detector that detects fluorescence, a second detector that detects scattered light, and information processing portion that classifies lymphocytes based on the intensity of fluorescence and scattered light, and based on the fluorescence intensity of the classified lymphocytes, obtains information regarding B-lymphocytes and T-lymphocytes. |
| US08524504B2 |
Sensor
This invention relates to a method for detecting an analyte in a sample, comprising the steps of exposing the sample to a transducer which is capable of transducing a change in energy to an electrical signal, the transducer having at least one tethered reagent on or proximal thereto, the at least one tethered reagent having a binding site which is capable of binding the analyte; introducing a labelled reagent into the sample, wherein the labelled reagent contains a binding site for the analyte or the tethered reagent and a label which is capable of absorbing electromagneticradiation generated by a radiation source to generate energy; allowing the labelled reagent to bind to the analyte or tethered reagent in a first period in which the transducer is oriented such that the labelled reagent is caused to settle, at least in part, on the transducer; subsequently, in a second period, causing the labelled reagent to become unsettled; irradiating the sample with electromagnetic radiation during the first and second periods, transducing the energy generated into an electrical signal; detecting the electrical signal. A device for performing the method is also provided. |
| US08524499B2 |
Regulatory sequences that direct gene expression to spinal motor neurons and uses thereof
The present invention relates to an enhancer which functions only in human brain and/or spinal cord motor neurons, where the enhancer comprises a nucleotide sequence of SEQ ID NO: 5, SEQ ID NO: 10, or SEQ ID NO: 16. The enhancer can be utilized as part of a nucleic acid construct which also has a nucleic acid encoding a marker protein or a therapeutic protein, a 3′ control region, and, optionally, a basal promoter, where these components are positioned with respect to one another to permit expression of the marker protein or the therapeutic protein. The enhancer of the present invention is useful in a method of isolating an enriched or purified population of motor neurons from a mixed population of human brain and/or spinal cells. In addition, the enhancer of the present invention can be used in a method of therapeutically targeting motor neurons. |
| US08524496B2 |
Adherent cells from placenta tissue and use thereof in therapy
A method of culturing adherent cells from a placenta or adipose tissue is disclosed. The method comprising culturing the adherent cells from the placenta or adipose tissue under 3 dimensional (3D) culturing conditions which allow cell expansion, the conditions comprising perfusion. |
| US08524493B2 |
Released cytokeratins as markers for epithelial cells
The present invention is directed to methods of detecting viable epithelial cells in a sample. The method includes isolating the sample comprising cells from a patient and culturing the cells for a time sufficient for an epithelial cell-specific marker to be released from the cells. The marker includes a substantially full-length cytokeratin. The method further includes detecting the released marker. Detection of the marker indicates the presence of disseminated epithelial cells. Methods are also directed to identifying disseminated epithelial tumor cells. |
| US08524492B2 |
Culture method for amplifying large numbers of hair follicle stem cells in vitro
The present invention is a method for amplifying a large numbers of hair follicle stem cells in vitro by using microspheres as carriers for cell culture and a revolving bottle as a fermentation tank for cell proliferation. The method includes digesting hair follicles to obtain hair follicle stem cells, seeding the cells on microcarriers, transferring the microcarriers to a revolving bottle, feeding liquid culture media into the revolving bottle, placing the revolving bottle into a cell incubator, growing the cells on the microcarrier and harvesting the hair follicle stem cells. |
| US08524491B2 |
Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated
Compounds and compositions for eliciting or enhancing immune reactivity to HER-2/neu protein are disclosed. The compounds include polypeptides and nucleic acid molecules encoding such peptides. The compounds may be used for the prevention or treatment of malignancies in which the HER-2/neu oncogene is associated. |
| US08524490B2 |
Fully automated portable DNA detection system
Provided herein is a portable thermocycler, comprising: (i) a case; (ii) a rotary plate in the case; (iii) a plurality of heating blocks arranged in a geometric pattern disposed on the rotary plate; and (iv) at least one vessel adapted to move and contact at least two of the plurality of heating blocks; wherein each of the heating blocks comprises a heating plate maintained at a set temperature over a thermally insulating material; wherein the geometric pattern comprises a number of center heating blocks arranged in a shape defining a polygon and a number of outside heating blocks disposed around the periphery of the rotary plate; and wherein the rotary plate includes a plurality of rotating wheels adapted to rotate at least one of the vessels into contact with each of the heating blocks. |
| US08524486B2 |
Culture method of Aantrodia camphorata
A culture method of a fruiting body of Antrodia camphorata is provided, which includes: (a) fermenting a culture medium containing yeast at 5-35° C. for 3-30 days; (b) adding wood flour to the fermented culture medium with stirring; (c) placing the wood flour and the culture medium into a vessel; (d) sterilizing the vessel containing the wood flour and the culture medium; (e) inoculating Antrodia camphorata strains into the sterilized vessel containing the wood flour and the culture medium, and culturing at 5-35° C., to form mycelia; (f) inoculating the wood flour containing Antrodia camphorata mycelia into a wood segment; (g) placing the wood segment inoculated with Antrodia camphorata mycelia in an environment where the temperature is 5-35° C. and the humidity is 65-85%, and culturing for a period of time; and (h) removing the wood flour remained on the wood segment, then placing the wood segment in an environment where the temperature is 15-35° C. and the humidity is 80-98%, and culturing for a period of time, to form a fruiting body of Antrodia camphorata. A culture method of Antrodia camphorata mycelia, a culture method of a fruiting body of Antrodia camphorata, and a fruiting body of Antrodia camphorata cultured by the same method are also provided. The fruiting body of Antrodia camphorata cultured by the method of the present invention is thick and solid, and the content of triterpenoids is comparable to that of wild Antrodia camphorata. |
| US08524480B2 |
Cytotoxic ribonuclease variants
This invention relates to altered forms of members of the RNase A superfamily. An RNase A can be modified to be cytotoxic by altering its amino acid sequence so that it is not bound easily by the ribonuclease inhibitor while still retaining catalytic properties. While earlier work had identified some modifications to RNase A that would result in cytotoxicity, the use of the FADE algorithm for molecular interaction analysis has led to several other locations that were candidates for modification. Some of those modifications did result in RNase A variants with increase cytotoxicity. |
| US08524477B2 |
Methods to obtain recombinant proteins with increased sialylation from cells that express adenovirus E1A protein, and proteins obtained thereby
Provided are compositions comprising one or more isoforms of an erythropoietin (“EPO”) comprising glycans linked thereto, wherein the glycans have Lewis x structures and on average at least six sialic acid moieties per EPO molecule. Further provided are methods for obtaining a composition comprising one or more isoforms of EPO comprising glycans linked thereto, wherein the glycans comprise on average at least six sialic acids per EPO molecule and from zero to two Lewis x structures, the method comprising: a) providing a eukaryotic cell containing a nucleic acid sequence encoding an adenoviral E1A protein in expressible format and a nucleic acid encoding EPO in expressible format, wherein the cell further contains a nucleic acid sequence encoding a sialyltransferase, e.g., an α-2,6-sialyltransferase or an α-2,3-sialyltransferase, under control of a heterologous promoter; b) culturing the cell in a serum-free culture medium and allowing expression of EPO in the cell; c) harvesting the expressed EPO from the cell and/or from the culture medium; and d) purifying and fractionating the EPO to obtain fractions that have an increased average sialic acid content of the N-linked glycans per EPO molecule, to obtain a composition comprising one or more isoforms of an EPO comprising glycans linked thereto, wherein the glycans comprise on average at least six sialic acids per EPO molecule and from zero to two Lewis x structures. |
| US08524476B2 |
Bacterium producing a product of a reaction catalyzed by a protein having 2-oxoglutarate-dependent enzyme activity and a method for manufacturing the product
A method for manufacturing a product of a reaction catalyzed by a protein having 2-oxoglutarate-dependent enzyme activity such as (2S,3R,4S)-4-hydroxy-L-isoleucine or a salt thereof using a bacterium transformed with a DNA fragment containing a gene coding for a protein having 2-oxoglutarate-dependent enzyme activity such as L-isoleucine dioxygenase activity; and wherein said bacterium has the ability to produce a product such as (2S,3R,4S)-4-hydroxy-L-isoleucine. |
| US08524474B2 |
Process for producing a concentrated sugar solution by enzymatic saccharification of polysaccharide enriched biomass
Methods for obtaining concentrated sugar solution from polysaccharide enriched biomass by contacting biomass with water and at least one nucleophilic base to produce a polysaccharide enriched biomass comprising a solid fraction and a liquid fraction and then contacting the solid fraction with saccharification enzyme consortium to produce a saccharification product comprising at least about 7 percent by weight sugars in 24 hours. The methods include optionally adding at least one additive selected from the group consisting of polyethylene glycols, fatty acid esters, fatty acid ethoxylates, nonionic surfactants derived from polyethoxylated sorbitan and a fatty acid, sodium lauriminodipropionate, sodium cocoamphoacetate, sodium tridecyl ether sulfate and a combination of these, such that enzyme loading of the saccharification enzyme consortium can be reduced. |
| US08524472B2 |
Method for producing 2-butanol and recombinant microorganism having 2-butanol production capacity
This invention is intended to produce 2-butanol with excellent productivity via a fermentation process. Recombinant microorganisms into which the acetoacetyl-CoA synthase gene and a group of genes (i.e., genes involved in 2-propanol synthesis) encoding a set of enzymes synthesizing 2-propanol from acetoacetyl-CoA have been introduced are cultured, so that, in addition to 2-propanol, 2-butanol is produced at a high level in a medium. |
| US08524466B2 |
Microvesicle membrane protein and application thereof
Microvesicles play essential roles in disease progression. The present invention provides a microvesicle membrane protein and application thereof. Disclosed is method comprises phosphorylated CSE1L (cellular apoptosis susceptibility protein- or CSE1L-binding agents for microvesicle isolation, analysis, or binding for disease diagnosis or treatment. |
| US08524463B2 |
Diagnosis and risk classification of acute coronary syndrome by means of CT-proET-1 in combination with NT-proBNP
The invention relates to a method for diagnosis and/or risk classification for acute coronary syndrome (ACS), in particular for acute myocardial infarct (AMI) and angina pectoris (AP) and/or a post-myocardial infarct, wherein a determination of the C-terminal pro-endothelin (CT-proET-1) or fragments and partial peptides therefrom, is carried out in combination with NT-proBNP. |
| US08524460B2 |
PSCA: prostate stem cell antigen and uses thereof
The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors. |
| US08524455B2 |
Methods and compositions related to TR4 ligand
Disclosed are compositions and methods related to TR4 and aging. |
| US08524453B2 |
Lectin complement pathway assays and related compositions and methods
This invention is related, in part, to assays for analyzing the lectin complement pathway (LCP) as well as to compositions and methods related thereto. |
| US08524452B2 |
Measurement value lowering inhibitor for immunoassay method and immunoassay method using the same
Disclosed is an agent for inhibiting decrease in measured values in immunoassays, which may reduce the influences by interfering substances in a test sample so as to promote the accuracy of the immunoassays, as well as an immunoassay and a reagent for immunoassays using the same, with which the decrease in the measured values due to the interfering substances is reduced. The agent for inhibiting decrease in measured values in immunoassays, caused by interfering substances, is an ionic surfactant having a molecular weight of 1000 to 100,000, the agent being a polymer in which a hydrophobic cyclic monomer(s) having an ionic functional group(s) is(are) polymerized. |
| US08524451B2 |
Method for real-time detection of Salmonella in food using a cleavable chimeric probe
A method is described for the real-time detection of Salmonella species in foods and on surfaces. Salmonella are enriched in media to increase their cell density prior to analysis. DNA is recovered by lysis in the presence of azide, proteinase K, and detergent. Real-time detection of Salmonella species is performed in a PCR reaction using gene specific primers and a cleavable chimeric fluorescent probe. The method also describes an internal control to confirm the efficiency of nucleic acid amplification and detection. The method is amenable to medium and high throughput analysis. |
| US08524450B2 |
Microvessels, microparticles, and methods of manufacturing and using the same
A method of reading a plurality of encoded microvessels used in an assay for biological or chemical analysis. The method can include providing a plurality of encoded microvessels. The microvessels can include a respective microbody and a reservoir core configured to hold a substance in the reservoir core. The microbody can include a material that surrounds the reservoir core and facilitates detection of a characteristic of the substance within the reservoir core. Optionally, the material can be transparent so as to facilitate detection of an optical characteristic of a substance within the reservoir core. The microbody can include an identifiable code associated with the substance. The method can also include determining the corresponding codes of the microvessels. |
| US08524446B2 |
Method for detecting adeno-associated virus
A method for detecting and isolating AAV sequences in a sample of DNA obtained from tissue or cells is provided, which sample contains DNA and proviral AAV. The method involves subjecting the sample containing DNA to amplification via polymerase chain reaction (PCR) using a first set of primers which specifically amplify a first AAV region. The first AAV region is characterized by having at least 250 nucleotides of AAV capsid nucleic acid sequence, a variable sequence flanked by a sequence of at least 18 nucleotides at the 5′ end of the first AAV region and a sequence of at least 18 nucleotides at the 3′ end of the first AAV region. Each of the 5′ and 3′ at least 18 nucleotides is the same over at least 9 consecutive nucleotides relative to corresponding sequences in an alignment of at least two AAV serotypes. Each of the sets of primers consist of a 5′ primer and a 3′ primer. The method is further useful for identifying AAV sequences in the sample by the presence of amplified proviral AAV sequences. |
| US08524444B2 |
Methods and compositions for detections and modulating O-glycosylation
The invention relates to methods and products for modulating glycosylation of proteins. The invention is useful for identifying therapeutic compounds to treat glycosylation-associated disorders such as neurodegeneration, diabetes, including complications of diabetes such as insulin resistance, nephropathy, microvascular damage, and endothelial dysfunction. The invention is also useful for identifying therapeutic compounds to treat de-glycosylation-associated disorders such as ischemic damage and traumatic injury. The invention also relates in part to assays that are useful for identifying and testing candidate compounds for modulating glycosylation of proteins and also relates in part to compounds to treat glycosylation-associated diseases and disorders. |
| US08524443B2 |
Method and apparatus for printing a periodic pattern with a large depth of focus
A method for printing a desired pattern into a photosensitive layer that includes providing a mask bearing a pattern of linear features that are parallel to a first direction, arranging the layer parallel to and separated from said mask, generating substantially monochromatic light, and illuminating the mask pattern with said light over a range of angles of incidence in a plane parallel to said first direction, at substantially a single angle in an orthogonal plane of incidence and so that the light of each angle of incidence transmitted by the mask forms a light-field component at the layer whereby the integration of said components prints the desired pattern, wherein the range of angles is selected so that the integration of said components is substantially equivalent to an average of the range of transversal intensity distributions formed between Talbot image planes by light at one of the angles of incidence. |
| US08524438B2 |
Etch resist solution, method of fabricating thin film pattern using the same and method of fabricating an LCD device using the same
A method of fabricating a thin film pattern improve the life of a blanket and reduce the cost and improve reliability in forming the thin film pattern. The method includes injecting an etch resist solution into a blanket on a printing roller, wherein the etch resist solution includes a printing solvent that satisfies the condition 6>δsolvent or δsolvent>11, where δsolvent is the solubility parameter of the solvent, or satisfies the condition 6<δsolvent<11 and μ<2(D), where μ is the dipole moment of the solvent; rotating the printing roller to uniformly coat the etch resist solution on the blanket; rolling the printing roller coated with the etch resist solution onto a printing plate to pattern the etch resist solution to thereby form an etch resist pattern; transferring the etch resist pattern from the printing roller to a substrate; hardening the etch resist pattern; and forming a desired thin film pattern on the substrate using the etch resist pattern. |
| US08524434B2 |
Toner and method for manufacturing toner
A toner having a toner particle including a core particle obtained by polymerizing a polymerizable monomer composition containing at least a polymerizable monomer, a colorant, a release agent, a polar resin, and a crystalline polyester in an aqueous medium and an outer shell formed by fixing resin fine particles to the surface of the core particle, wherein the resin constituting the resin fine particles is an amorphous resin and the acid value of the resin fine particles is 4.0 to 50.0 mgKOH/g. |
| US08524433B2 |
Electrophotographic photoconductor, process cartridge, and image forming apparatus
An electrophotographic photoconductor includes a conductive substrate and an outermost surface layer formed on the conductive substrate and containing a binder resin and a copolymer derived from a reactive monomer having charge transport property and a reactive monomer having no charge transport property, the copolymer having a side chain with 4 or more carbon atoms in a constitutional unit derived from the reactive monomer having no charge transport property. |
| US08524432B2 |
Electrophotographic photoreceptor, process cartridge, and image forming apparatus
An electrophotographic photoreceptor includes a conductive substrate, and at least a photosensitive layer on the conductive substrate, a layer located at a surface of the photosensitive layer side of the electrophotographic photoreceptor contains fluorine containing resin particles and a fluoro graft polymer having a fluoroalkyl group having 1 to 7 carbon atoms, and an area for a polystyrene equivalent molecular weight of 700,000 or more is from about 5% to about 20% of the total area in a gel permeation chromatography (GPC) chart for the fluoro graft polymer. |
| US08524431B2 |
Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus
The electrophotographic photosensitive member includes a conductive support and an intermediate layer, a charge generation layer and a charge transport layer, which are provided on the conductive support in this order. The intermediate layer contains an ethylene-acrylic acid binary copolymer and a polyolefin resin in which repeating structural units are contained in a particular ratio. |
| US08524426B2 |
Method of manufacturing a photomask
A method for correcting a position error of a lithography apparatus comprises inputting position data of exposure pattern, irradiating laser light onto a position reference mask from a position measurement laser system, calculating actual position data of the laser light irradiated onto the position reference mask, and comparing the position data of the exposure pattern with the actual position data of the laser light irradiated onto the position reference mask. With this method, circuit patterns can be accurately formed at predetermined positions on a photomask, and the circuit patterns on the photomask can be accurately formed at predetermined positions on a wafer. |
| US08524424B2 |
Optical proximity correction photomask
An optical proximity correction (OPC) photomask is provided. The photomask includes two opening patterns and a pair of scattering bar patterns. The two patterns are arranged on a substrate along a first direction and separated from each other by a predetermined distance. The pair of scattering bar patterns is arranged on the substrate along a second direction perpendicular to the first direction and adjacent to two opposing sides of each opening pattern. Each scattering bar pattern does not overlap with the opening patterns on the first and second directions as viewed from a cross sectional perspective. A phase shift of 180° exists between each opening pattern and each scattering bar pattern. |
| US08524423B2 |
Method of forming assist feature patterns
A method of forming assist feature patterns includes providing an original layout pattern having at least a first region defined therein, the first region having a first light transmission rate larger than 0%; performing a search step to the original layout pattern to define at least a second region having a second light transmission rate equal to 0% in the original layout pattern; forming a plurality of assist features in the second region to increase the second light transmission rate to larger than 0%; and outputting the original layout pattern and the assist features to a reticle blank. |
| US08524421B2 |
Mask blank, transfer mask, methods of manufacturing the same and method of manufacturing a semiconductor device
In a mask blank for manufacturing a transfer mask, the mask blank has a light-shielding film on a transparent substrate. The light-shielding film is made of a material containing tantalum as a main metal component and includes a highly oxidized layer which has an oxygen content of 60 at % or more and which is formed as a surface layer of the light-shielding film. The highly oxidized layer is placed on a side opposite to a transparent substrate side. |
| US08524420B2 |
Method for preparing nano-sized metal particles on a carbon support
Disclosed is a method for preparing nickel or palladium nanoparticles supported on a carbon support. To a mixture solution wherein a stabilizer is dissolved in 1,2-propanediol, a carbon support is added to prepare a dispersion. Then, a precursor solution wherein a nickel or palladium precursor dissolved in 1,2-propanediol is mixed therewith and stirred. Then, nickel or palladium nanoparticles supported on the carbon support are prepared by reduction. The disclosed method for preparing nickel or palladium nanoparticles supported on a carbon support allows preparation of nanoparticles with narrow particle size distribution and good dispersibility through a simple process and the resulting nickel or palladium nanoparticles may be usefully applied, for example, as electrode materials of fuel cells. |
| US08524419B2 |
Electrode support for fuel cells
An electrode support for fuel cells, the electrode support being made of a porous material having a Ni phase of Ni or NiO and an inorganic skeletal material phase, wherein an oxidation/reduction expansion-suppressing metal M of at least one selected from the group consisting of Fe, Co and Mn is solidly dissolved in the Ni phase or is biasedly distributed on the grain boundaries between the Ni phase and the inorganic skeletal material phase. The electrode support has its volume very little expanded or contracted even in an environment in which it is exposed to the reducing atmosphere and the oxidizing atmosphere alternately. The fuel cell having the fuel electrode, electrolyte layer and oxygen electrode formed on the electrode support effectively prevents the occurrence of cracks or exfoliation caused by expansion and the like when the reduction/oxidation cycle is repeated accompanying the generation of electricity and stop of generation, and maintains reliability very excellently over extended periods of time. |
| US08524412B2 |
Fuel cell fabrication using photopolymer based processes
A fuel cell component is provided, including a substrate disposed adjacent at least one radiation-cured flow field layer. The flow field layer is one of disposed between the substrate and a diffusion medium layer, and disposed on the diffusion medium layer opposite the substrate. The flow field layer has at least one of a plurality of reactant flow channels and a plurality of coolant channels for the fuel cell. The fuel cell component may be assembled as part of a repeating unit for a fuel cell stack. A method for fabricating the fuel cell component and the associated repeating unit for the fuel cell is also provided. |
| US08524408B2 |
Stack operation method aimed at cell reversal prevention
A method for preventing a fuel cell voltage potential reversal including determining a relationship between the cell resistance and the current of a fuel cell stack at which a fuel cell voltage potential reversal will occur, operating the fuel cell stack according to a power demand requested, and determining the maximum cell resistance of the fuel cells in the stack. If the maximum cell resistance exceeds a threshold value for the current at which the fuel cell stack is being operated, the operation of the fuel cell stack is restricted to prevent the fuel cell voltage potential from reversing. |
| US08524404B2 |
Fuel cell anode stoichiometry control
A system and method for controlling an anode exhaust gas bleed valve in a fuel cell system that includes estimating the gas composition in the anode exhaust gas, using an inverse valve model to calculate a desired valve flow coefficient, and bleeding the anode exhaust gas at a flow rate that results in the desired valve flow coefficient. The method includes determining the partial pressure of nitrogen in the anode exhaust gas, calculating the partial pressure of water vapor and hydrogen in the anode exhaust gas, and calculating the gas mole fraction of the nitrogen, water vapor and hydrogen in the anode exhaust gas. The method also includes using the gas mole fraction of nitrogen, water vapor and hydrogen to determine the desired valve flow coefficient, and using the desired valve flow coefficient to determine when to open and close the bleed valve. |
| US08524401B2 |
Electrolyte for lithium battery and lithium battery including the same
An electrolyte for a lithium battery and a lithium battery including the electrolyte. |
| US08524400B2 |
Non-aqueous electrolyte and secondary battery using the same
Disclosed is an electrolyte for a secondary battery comprising an electrolyte salt and an electrolyte solvent, the electrolyte comprising both a lactam-based compound and a sulfinyl group-containing compound. Also, disclosed is an electrode having a solid electrolyte interface (SEI) film partially or totally formed on a surface thereof, the SEI film being formed by electrical reduction of the above compounds. Further, a secondary battery comprising the electrolyte and/or the electrode is disclosed. |
| US08524395B2 |
Nonaqueous electrolyte secondary battery anode material with a uniform metal-semiconductor alloy layer
The present invention relates to nonaqueous electrolyte secondary batteries and durable anode materials and anodes for use in nonaqueous electrolyte secondary batteries. The present invention also relates to methods for producing these anode materials. In the present invention, a metal-semiconductor alloy layer is formed on an anode material by contacting a portion of the anode material with a displacement solution. The displacement solution contains ions of the metal to be deposited and a dissolution component for dissolving a part of the semiconductor in the anode material. When the anode material is contacted with the displacement solution, the dissolution component dissolves a part of the semiconductor in the anode material thereby providing electrons to reduce the metal ions and deposit the metal on the anode material. After deposition, the anode material and metal are annealed to form a uniform metal-semiconductor alloy layer. |
| US08524394B2 |
Negative electrode and negative active material for rechargeable lithium battery, and rechargeable lithium battery including same
Negative active materials, negative electrodes, and rechargeable lithium batteries are provided. A negative electrode according to one embodiment includes a non-carbon-based active material, a lithium salt having an oxalatoborate structure, and a high-strength polymer binder. The negative active material may include a non-carbon-based material and a coating layer on the non-carbon-based material. The coating layer includes a lithium salt having an oxalatoborate structure and a high-strength polymer binder. A rechargeable lithium battery including the negative electrode or negative active material has good cycle life characteristics and high capacity. |
| US08524391B2 |
Rechargeable battery pack
A rechargeable battery pack including a cap cover through which a protection element may be easily mounted and a coupling terminal which is integrally manufactured when forming the cap cover includes: a bare cell having an electrode terminal; a cap cover coupled to a leading side of the electrode terminal of the bare cell, and on which a through hole is formed; a first coupling terminal attached to an external side of the cap cover; and a protection element accommodated in the cap cover, electrically connected to the electrode terminal via a first coupling lead, and electrically connected to the first coupling terminal via the through hole by a second coupling lead. |
| US08524389B2 |
Plate for a bipolar battery and a bipolar battery
The present invention relates to a plate (20), particularly for a bipolar battery (10), the plate (20) being of the type that comprises a base graphite material (2), a positive active material (3) applied to a first surface (4) of the base material (2) and a negative active material (5) applied to a second surface (6) of the base material (2) opposite the first surface (4), the positive active material (3) having a composition that comprises lead dioxide, conductive carbon fibers and glass microspheres, and the negative active material (5) having a composition that comprises spongy lead, graphite additives and glass microspheres. One further describes a bipolar battery (10) formed by a plurality of plates (20), each plate (20) comprising a graphite base material (2), positive active material (3) applied to the first surface (4) of the base material (2) and negative active material (5) applied to a second surface (6) of the base material (2), opposite the first surface (4), the positive active material (3) of the plurality of plates (20) having a composition that comprises lead dioxide, conductive carbon fibers and glass microspheres, and the negative active material (5) of the plurality of plates (20) having a composition that comprises spongy lead, graphite additives and glass microspheres. |
| US08524388B2 |
Superbase-derived protic ionic liquids
Protic ionic liquids having a composition of formula (A−)(BH+) wherein A− is a conjugate base of an acid HA, and BH+ is a conjugate acid of a superbase B. In particular embodiments, BH+ is selected from phosphazenium species and guanidinium species encompassed, respectively, by the general formulas: The invention is also directed to films and membranes containing these protic ionic liquids, with particular application as proton exchange membranes for fuel cells. |
| US08524387B2 |
Battery unit for hybrid or electric vehicles
A battery unit for hybrid or electric vehicles comprising a cell module including a plurality of storage cells, each accommodated in a prismatic cell casing with two large surfaces arranged parallel to each other and four narrow side surfaces. The prismatic cell casings with their parallel arranged large surfaces are stacked adjacent to each other. One of the narrow side surfaces, the cell casing bottom of each storage cell. A cooling device comprising a plate-shaped cooling body with one or several recesses, and one or several fastening mechanisms integrated into the cell module bottom that agree with a corresponding number of recesses of the cooling body, are configured to couple the cooling body to the cell module. |
| US08524385B2 |
Battery pack
A battery pack has a secondary battery, first and second switch devices provided between the secondary battery and a load or a charging unit, a protection circuit detecting an overcharge, an overdischarge or an overcurrent of the secondary battery and controlling turning on and off of the first and second switch devices, a series circuit of a resistor and a thermistor disposed in the vicinity of the secondary battery and connected in parallel with the secondary battery, a comparator which compares a voltage at a connection point between the thermistor and the resistor with a reference voltage corresponding to a predetermined temperature inside the protection circuit, and a third switch device connected between the resistor and a negative electrode of the secondary battery. The protection circuit turns off the first switch device and the third switch device when an overdischarge of the secondary battery is detected. |
| US08524381B2 |
Organometallic complex for organic light-emitting layer and organic light-emitting diode using the same
An organometallic complex represented by Formula 1 is provided. An organic light-emitting diode using the organometallic complex exhibits improved current and power efficiency and long lifetime. |
| US08524380B2 |
Heterocyclic compound and organic light-emitting device including the same
Embodiments of the present invention are directed to heterocyclic compounds and organic light-emitting devices including the heterocyclic compounds. The organic light-emitting devices using the heterocyclic compounds have high-efficiency, low driving voltages, high luminance and long lifespans. |
| US08524379B2 |
Organic electroluminescence device and display unit
An organic electroluminescence device capable of realizing both high light emitting efficiency and high reliability with an inexpensive structure is provided. The organic electroluminescence device includes an organic layer including a light emitting layer between an anode and a cathode. The anode has a laminated structure including a first layer composed of aluminum (Al) or an alloy containing aluminum as a main component and a second layer that is provided between the first layer and the organic layer and is composed of an alloy containing aluminum as a main component, and a resistance of the first layer is lower than a resistance of the second layer. |
| US08524378B2 |
Copper foil for printed circuit
Provided is a copper foil for a printed circuit with an electrodeposited ternary-alloy layer composed of copper, cobalt and nickel formed on a surface of the copper foil, wherein the electrodeposited layer comprises dendritic particles grown on the copper foil surface, and the entire surface of the copper foil is covered with particles having an area as seen from above the copper foil surface of 0.1 to 0.5 μm2 at a density of 1000 particles/10000 μm2 or less, particles exceeding 0.5 μm2 at a density of 100 particles/10000 μm2 or less, and particles less than 0.1 μm2 as the remainder. Roughening particles formed dendritically in a roughening treatment based on copper-cobalt-nickel alloy plating are inhibited from shedding from the copper foil surface, and the phenomenon known as powder falling and uneven treatment are thereby inhibited. |
| US08524375B2 |
Thermal spray coated work rolls for use in metal and metal alloy sheet manufacture
This invention relates to thermally spray coated work rolls for use in metal or metal alloy, e.g., aluminum alloy, sheet manufacture comprising a cylindrical-like structure having an outer peripheral surface and a thermally sprayed coating on the outer peripheral surface of said cylindrical-like structure, said thermally sprayed coating comprising from about 65 to about 95 weight percent of one or more Group VI metal carbides, and from about 5 to about 35 weight percent of one or more transition metals selected from chromium, manganese, iron, cobalt and nickel. This invention also relates to a process for preparing the work rolls for use in metal or metal alloy, e.g., aluminum alloy, sheet manufacture, a method for manufacturing metal or metal alloy, e.g., aluminum alloy, sheet using the thermally spray coated work rolls, and a thermal spray powder for coating the outer peripheral surface of the work rolls for use in metal or metal alloy, e.g., aluminum alloy, sheet manufacture. |
| US08524374B2 |
Tissue Product comprising bamboo
The disclosure provides tissue webs, and products incorporating the same, where the webs comprise wood and bamboo fibers. More specifically the disclosure provides soft and durable through-air dried tissue webs comprising at least about 10 percent bamboo fiber by weight of the web. In the through-air dried tissue webs of the present disclosure, bamboo typically replaces high average fiber length wood fibers, which increases the bulk of the through-air dried web without negatively effecting softness or durability. |
| US08524365B2 |
Preparation of nanoparticle materials
A method of producing nanoparticles comprises effecting conversion of a nanoparticle precursor composition to the material of the nanoparticles. The precursor composition comprises a first precursor species containing a first ion to be incorporated into the growing nanoparticles and a separate second precursor species containing a second ion to be incorporated into the growing nanoparticles. The conversion is effected in the presence of a molecular cluster compound under conditions permitting seeding and growth of the nanoparticles. |
| US08524363B2 |
Organosilicone fine particles of tetrahedral general shapes, method of production thereof and cosmetic materials, resin compositions and paint compositions containing same
Organosilicone fine particles which are capable of responding to the highly advanced requirements of recent years imposed on them for purposes of actual use, including further improvement in optical characteristics such as total light transmittance and haze as well as heat-resistant colorability related to resin compositions, further improvement in usability (extensions and expansions at the time of use) and feeling (stickiness, roughness and durability) related to cosmetic materials and further improvement in matte effect and factual sense related to paint compositions, as well as methods of their production and cosmetic materials, resin compositions and paint compositions containing such particles are provided. Organosilicone fine particles have tetrahedral general shapes with surfaces each having a concave part with an approximately circular opening. The maximum external diameters L of the organosilicone fine particles have an average value in the range of 0.5-20 μm, the average value being taken from arbitrarily selected 20 of a scanning electron microscope photograph image of the organosilicone fine particles. |
| US08524362B2 |
Doped pnictogen chalcogenide nanoplates, methods of making, and assemblies and films thereof
Embodiments of the invention are directed to doped pnictogen chalcogenide nanoplates, where each nanoplate comprises a rhombohedral crystal of Bi2Te3, Bi2Se3, or Sb2Te3 that is sulfur doped. Another embodiment of the invention is directed to a microwave activated method of preparation of the doped pnictogen chalcogenide nanoplates. Other embodiments of the invention are directed to bulk assemblies or fused films of the doped pnictogen chalcogenide nanoplates and their preparation from the doped pnictogen chalcogenide nanoplates such that the bulk assembly or fused film can be employed in a thermoelectric device. |
| US08524360B2 |
Cutting insert with a titanium oxycarbonitride coating and method for making the same
A method for making a coated cutting insert, as well as the coated cutting insert, includes a step of providing a substrate which has a surface, and depositing a CVD coating layer of titanium oxycarbonitride. The gaseous mixture from which the coating layer of titanium oxycarbonitride is deposited has a composition of nitrogen, methane hydrogen chloride, titanium tetrachloride, acetonitrile, carbon monoxide, and hydrogen. The coating layer of titanium oxycarbonitride comprises titanium oxycarbonitride whiskers having as measured in a two-dimensional plane view an average length greater than about 1.0 μm, an average width greater than about 0.2 μm, and an average aspect ratio greater than about 2.0. |
| US08524358B2 |
Configuration of multiple thermoformable film layers for rigid packaging requiring moisture and oxygen protection
A four-layer film for packaging, including blister packaging, is described. Layer 1 may be a rigid film, such as a polyvinyl chloride (PVC) or polyester. Layer 2 may be a moisture barrier, such as polychlorotrifluoroethylene (PCTFE). Layer 3 may be an oxygen barrier, such as a co-extruded film having a polyethylene (PE) layer, an EVOH layer, and a second PE layer. Layer 4 may be a relatively thin layer of a rigid film, such as a PVC or polyester. In this arrangement, Layer 2 may protect the contents of the package from external or atmospheric moisture. Layer 2 may also protect Layer 3 from atmospheric moisture, thereby helping to preserve the effectiveness of Layer 3 as an oxygen barrier. |
| US08524351B2 |
Composite panel
A door panel 1 has a peripheral frame 10 of extruded aluminum and a honeycomb core of plastics material tubes 11. An outer skin 2 of fiber-reinforced polyetherimide material is recessed with a pattern 3 formed in a preliminary operation of vacuum/pressure forming at elevated temperature. An inner skin 4 is plane. Edge channel members 5 of similarly formed, but thicker material are arranged around the edges of the door, enclosing the aluminum frame. A non-woven, polyester based scrim 6 extends across either side of the core and over the flanges 7 of the edge channels.For bonding of the core, skin and edge channels together, the assembly is placed in a jig and compressed at elevated temperature in a heated press. The core is crushed at the recessed pattern 3 and the scrim melts and acts as a hot melt adhesive. On cooling of the press platens, the assembled door is removed from the jig. |
| US08524345B2 |
Pipe module
A temporary part is fixed to a base by using an adhesive layer to which fillers are mixed at a predetermined density. When the temporary part is heated, heat is applied to the fillers and the adhesive layer. At a temperature equal to or higher than the glass-transition temperature of the adhesive agent, the heated adhesive layer is thermally contracted so as to release remaining stress, and on the other hand, the heated fillers are thermally expanded. In this manner, the peel-off strength between the adhesive layer and the base (or the temporary part) is reduced, and the disassembly is facilitated. |
| US08524344B1 |
Polymeric vessel
A polymeric vessel includes a first shell formed from a thermoplastic polymer and including a weld stub, and a second shell formed from the thermoplastic polymer and including a weld anvil matable with the weld stub. The polymeric vessel also includes a friction weld joint joining the weld stub and the weld anvil, and a coupling element interconnecting the first shell and the second shell and spaced apart from the friction weld joint. |
| US08524341B2 |
Alloy composition useful for fluid transport objects
The present invention relates to a novel polyamide alloy composition that is useful for forming objects that may be used for the storage and transport of fluids. The polyamide alloy is a blend of at least one polyamide and at least one modified polyolefin having both medium to hard and soft domains. The polyamide forms the continuous phase of the alloy. The alloy may also contain, and preferably does contain, a thermal and light stabilization compound, at least one unmodified polyolefin, and at least one plasticizer. The polyamide alloy composition is useful in forming tanks, hoses and tubes used in the transport of liquid or gaseous fluids, including fluids under pressure. |
| US08524340B2 |
Primary molded product for biaxial stretch blow molded bottle body, and bottle body
The preform of the biaxially drawn, blow-molded bottle comprises polyethylene terephthalate layers 2 and at least a gas barrier layer 3 laminated with the polyethylene terephthalate layers. The gas barrier layer 3 extends downward from a level halfway to the height of the neck 4 including the neck ring 5, or at least from above the neck ring 5, down virtually to the lower end of body 6. The gas barrier layer 3 inside the wall of the neck 4 has an average thickness corresponding to a third (⅓) or less of the maximum thickness of the gas barrier layer 3 inside the wall of the body 6, allowing most of the gas barrier material to be located in the wall of the body 6. Thus, the gas barrier material is effectively utilized, and in the case of the heat-resistant bottle, the neck has the predetermined dimensions without fail after the whitening treatment. |
| US08524338B2 |
Impact energy attenuation system
A new and novel impact energy attenuation material, impact energy attenuation module employing the material and a fit system for optimizing the performance thereof is provided. Non-linear energy attenuating material consisting of a plurality of loose particles is employed for impact energy dissipation. The loose particles are preferably spherical elastomeric balls. An impact energy attenuation module includes a container that holds the loose particles. The impact energy attenuation module can be provided in a wide range of sizes and shapes and the loose particles can be provided in different materials, sizes, density, compaction and hardness to suit with the application at hand. A matrix of impact energy attenuation module are provided about the surface of a shell to provide the required impact energy attenuation. The material, impact energy attenuation module and system of the present invention are well suited for protection of body parts and other cushioning and protection needs. |
| US08524333B2 |
Method of manufacturing gas barrier film
The method of manufacturing a gas barrier film feeds long lengths of a substrate and forms a silicon nitride film as the gas barrier film on the substrate by a capacitively coupled plasma-enhanced CVD technique while transporting the substrate in a longitudinal direction. Gaseous raw materials using in the forming step of the silicon nitride film includes at least silane gas and ammonia gas, and a ratio P/Q [W/sccm] is not less than 1 when a flow rate of the silane gas is denoted as Q [sccm] and a power input for generating a capacitively coupled plasma is denoted as P [W], a tension applied to the substrate transported between two transporting elements is not more than 100 [N/m], and a pair of electrodes for at least forming the silicon nitride film on the substrate is interposed between the two transporting elements. |
| US08524331B2 |
Substrate processing method
A substrate processing method effectively suppresses non-uniformity in deposition degree on a surface of a substrate. The substrate processing method includes depositing a deposit on a sidewall of each opening of a resist pattern, which is formed on an antireflection film on an etching target film of the substrate and is provided with a plurality of openings, before etching the etching target film of the substrate. Plasma is generated in the depositing process by introducing a CHF-based gas into the processing chamber at a flow rate equal to or higher than about 1000 sccm while a pressure in the processing chamber is set to equal to or higher than about 100 mTorr. |
| US08524329B2 |
Electroless copper deposition
A method for providing electroless plating is provided. An amorphous carbon barrier layer is formed over the low-k dielectric layer by providing a flow a deposition gas, comprising a hydrocarbon, H2, and an oxygen free diluent, forming a plasma from the deposition gas, and stopping the flow of the deposition gas. The amorphous carbon barrier layer is conditioned by providing a flow of a conditioning gas comprising H2 and a diluent, forming a plasma from the conditioning gas, which conditions a top surface of the amorphous carbon barrier layer, and stopping the flow of the conditioning gas. The amorphous carbon barrier layer is functionalized by providing a flow of a functionalizing gas comprising NH3 or H2 and N2, forming a plasma from the functionalizing gas, and stopping the flow of the functionalizing gas. An electroless process is provided to form an electrode over the barrier layer. |
| US08524322B2 |
Combination CVD/ALD method and source
The present invention relates generally to methods and apparatus for the controlled growing of material on substrates. According to embodiments of the present invention, a precursor fed is split in to two paths from a precursor source. One of the paths is restricted in a continuous manner. The other path is restricted in a periodic manner. The output of the two paths converges at a point prior to entry of the reactor. Therefore, a single precursor source is able to fed precursor in to a reactor under two different conditions, one which can be seen as mimicking ALD conditions and one which can be seen as mimicking CVD conditions. This allows for an otherwise single mode reactor to be operated in a plurality of modes including one or more ALD/CVD combination modes. |
| US08524321B2 |
Reagent dispensing apparatus and delivery method
This invention relates to a vapor or liquid phase reagent dispensing apparatus having a metal seal aligned and in contact with hardened opposing flat surfaces of a top wall member and a protuberance on a side wall member, wherein the hardened opposing flat surfaces of the top wall member and the protuberance have a hardness greater than the hardness of said metal seal. The dispensing apparatus may be used for dispensing of reagents such as precursors for deposition of materials in the manufacture of semiconductor materials and devices. |
| US08524319B2 |
Methods for producing crucibles with a reduced amount of bubbles
Methods for producing crucibles for holding molten material that contain a reduced amount of gas pockets are disclosed. The methods may involve use of molten silica that may be outgassed prior to or during formation of the crucible. Crucibles produced from such methods and ingots and wafers that are produced from crucibles with a reduced amount of gas pockets are also disclosed. |
| US08524318B2 |
Method of forming ice-phobic coating
The present invention relates to a method for reducing gas hydrate adhesion to the interior surface of a conduit and associated equipment transporting or processing a fluid stream in oil and gas exploration and production, petroleum refining and/or petrochemistry, by providing the conduit interior surface with a coating layer exhibiting a static contact angle of the sessile water drop on the coating layer in air higher than 75° at ambient air conditions, as measured according to ASTM D7334-08, wherein said coating layer comprises diamond like carbon (DLC) comprising fractions of one or more components selected from the group consisting of silicon (Si), oxygen (O) and fluor (F). |
| US08524310B2 |
Cereal flour composition containing wheat flour from low-temperature gelatinized wheat and food product using the same
An object of the present invention is to provide a cereal flour raw material that can provide products having superb texture. A further object of the present invention is to provide a food product manufactured using such a cereal flour raw material. The present invention provides a cereal flour composition that contains wheat flour prepared from a type of wheat that does not express any two of the three wheat starch synthase II proteins, and also does not express the three wheat granule bound starch synthase proteins, and another type of cereal flour; and a food product manufactured using such a cereal flour composition. |
| US08524309B2 |
Oil or fat composition
Provided is an oil or fat composition of high diacylglycerol content. Even when used in cooking, the cooked food has a good external appearance without darkening, and retains its inherent flavor. Even when used in cooking after storage under light-exposed conditions, the cooked food is provided with a good external appearance and flavor.The oil or fat composition is obtained by combining, at specific contents, (A) an oil or fat of high diacylglycerol content, said oil or fat having a particular composition, (B) a plant sterol and (C) a plant sterol fatty acid ester. |
| US08524307B2 |
Healthy coffee and methods of its production
The present invention relates to a method for producing a coffee blend and the coffee blend obtained by this method, wherein the coffee blend is characterized in that a coffee drink brewed from said coffee blend contains high amounts of chlorogenic acids (CGA) and N-methylpyridinium cations (NMP) and optionally, low amounts of carboxylic acid-5-hydroxytryptamides (C5-HT), has a superior antioxidative activity. |
| US08524304B2 |
High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith
The present invention relates generally to functional sweetener compositions comprising non-caloric or low-caloric natural and/or synthetic high-potency sweeteners and methods for making and using them. In particular, the present invention relates to different functional sweetener compositions comprising at least one non-caloric or low-caloric natural and/or synthetic high-potency sweetener, at least one sweet taste improving composition, and at least one functional ingredient, such as a probiotic, a prebiotic, or combination thereof. The present invention also relates to functional sweetener compositions and methods that can improve the tastes of non-caloric or low-caloric high-potency sweeteners by imparting a more sugar-like taste or characteristic. In particular, the functional sweetener compositions and methods provide a more sugar-like temporal profile, including sweetness onset and sweetness linger, and/or a more sugar-like flavor profile. |
| US08524302B2 |
Natural flavour enhancers and methods for making same
The present invention pertains to the use of certain flavor enhancing compounds obtainable from an Allium species. In one embodiment, seeds from chives, leeks, ramson and other onions are used for conveying strong kokumi flavor enhancing effects on food products without imparting an onion or garlic-like off taste. These flavor enhancing compounds are also useful for the preparation of Amadori products, which are also used as kokumi flavor enhancing compounds. |
| US08524295B2 |
Thermally stable, high tensile strength encapsulated actives
In some embodiments there is a composition including a thermally stabilized active composition and a high molecular weight polymer. The thermally stabilized active composition is resistance to degradation at higher temperatures such as those used for conducting extrusion with high molecular weight polyvinyl acetate. |
| US08524291B2 |
Anti-obesity product and its method of preparation
The present invention relates to compositions comprising one or more anthraquinones for use in the treatment of obesity and related metabolic and liver disease. More particularly it relates to a plant extract fraction rich in anthraquinones including both anthraquinone glycosides and anthraquinone aglycones obtainable from a member of the Leguminosae family, more particularly Cassia seeds. It also relates to a method of obtaining a plant extract fraction rich in anthraquinones. |
| US08524288B2 |
Compositions and methods for altering stool quality in an animal
The present invention provides compositions and methods for improving stool quality of a puppy by adjusting the balance of metabolizable cations to metabolizable anions consumed by the puppy. |
| US08524280B2 |
Methods for enhancing the release and absorption of water insoluble active agents
Methods for enhancing the release and/or absorption of poorly water soluble active agents are described herein. The method involves dissolving, melting, or suspending a poorly water soluble active agent in one or more molten fatty acids, conjugated fatty acids, (semi-) solid surfactants of high HLB value, and/or hydrophilic polymers. The molten active agent mixture is then suspended and homogenized in a hydrophilic or lipophilic carrier to form microparticles suspended in the hydrophilic or lipophilic carrier. The particles suspended in the hydrophilic or lipophilic carrier can be encapsulated in a hard or soft gelatin or non-gelatin capsule. It is believed that the microparticles produced by the method described above will exhibit enhanced dissolution profiles. In vitro release studies of formulations containing cilostazol and fenofibrate showed 100% dissolution of cilostazol in 15 minutes and over 90% dissolution of fenofibrate in 35 minutes. |
| US08524277B2 |
Extended release dosage form
A membrane system comprising an interior wall, a fluid-permeable exterior wall surrounding the interior wall and an internal compartment defined by the membrane system, wherein fluid permeability of the interior wall is responsive to osmolarity of an osmotic core within the internal compartment are disclosed. A controlled release dosage form comprising the membrane system and a process for delivering an osmotically active formulation from an osmotic pump over an extended period of time are also disclosed. |
| US08524275B2 |
Pharmaceutical formulations containing opioid agonist, opioid antagonist and gelling agent
Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of an opioid analgesic, an opioid antagonist and one or more pharmaceutically acceptable excipients; the dosage form further including a gelling agent in an effective amount to impart a viscosity unsuitable for administration selected from the group consisting of parenteral and nasal administration to a solubilized mixture formed when the dosage form is crushed and mixed with from about 0.5 to about 10 ml of an aqueous liquid. |
| US08524266B2 |
Polymers of fluorinated monomers and hydrocarbon monomers
It is a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer. |
| US08524254B2 |
Bioresorbable polymers
A bioresorbable polymer is obtained by reacting together (a) a prepolymer comprising co-polymerised units of a caprolactone and poly(alkylene oxide) moieties; (b) a polycaprolactone diol comprising co-polymerised units of a caprolactone and a C2-C6 diol; and (c) a diisocyanate. The polymer may be loaded with a pharmaceutically active agent to produce a drug delivery device. |
| US08524253B2 |
Bone regeneration device
This invention is directed to a bone regeneration device including fascia and demineralized bone matrix mixed at a temperature not exceeding about 40° C. and lyophilized into the bone regeneration device, methods of preparing such a bone regeneration device and methods of treating bone defects using such a bone regeneration device. |
| US08524252B2 |
Temperature sensitive vaccine strain of Mycoplasma hyopneumoniae and uses thereof
The present invention relates to a Mycoplasma hyopneumoniae vaccine strain comprising a mutation in at least one of the genes listed or as deposited with the National Measurements Institute (Australia) under accession number NM04/41259, which strain is temperature sensitive and attenuated, a vaccine comprising such strains and methods and uses thereof. |
| US08524249B2 |
Vaccines for inclusion body hepatitis
A composition comprising an isolated fowl adenovirus (FAdV), wherein the FAdV is a strain selected from FAdV-2, FAdV-7, FAdv-8a, FAdV-8b, FAdV-8a/8b or FAdV-11 serotype strains; and a suitable carrier and methods for inducing protective immunity in a subject and/or its progeny. |
| US08524242B2 |
Soluble aggregate, immune tolerance inducer and manufacturing method thereof
A soluble aggregate of allergen proteins, prepared by heating multiple allergen proteins and aggregating the allergen proteins and thus enclosing the antigen structures causing allergic reactions therein. |
| US08524239B2 |
Photosensitizing antibody-fluorophore conjugates
The present disclosure relates to compositions and methods of killing cells in vitro or in vivo. In particular examples, the method includes contacting a cell having a cell surface protein with a therapeutically effective amount of an antibody-IR700 molecule, wherein the antibody specifically binds to the cell surface protein. In particular examples the antibody recognizes a tumor-specific antigen on the surface of a tumor cell. The cell is subsequently irradiated, such as at a wavelength of 660 to 740 nm at a dose of at least 1 J cm−2, thereby killing the cell. Also provided are wearable devices that include an article of clothing, jewelry, or covering; and an NIR LED incorporated into the article, which can be used with the disclosed methods. |
| US08524228B2 |
Netrin-1 compositions and methods of use thereof
Methods and compositions for male or female contraception are provided. The compositions include an effective amount of netrin-1 to reduce or inhibit sperm concentration in semen of males or to inhibit or reduce fusion of male gametes with female gametes in a female subject Still another embodiment provides a method for diagnosing male infertility by determining the amount of netrin-1 in a sample of epididymal fluid or semen from a male subject, comparing the amount of netting-1 in the sample to levels of netrin-1 in samples of epididymal fluid or semen from fertile males, wherein levels of netrin-1 in the sample from the male subject that are higher or lower than levels of netrin-1 in samples from fertile males are indicative of male infertility in the male subject. |
| US08524226B2 |
Methods of prolonging patency of hemodialysis access
The invention provides methods for treating an obstructed biological conduit that include administering to the conduit an agent that can degrade extracellular matrix of obstructing tissue. Particular methods include delivery of an enzyme or a mixture of several enzymes to the area or region of obstruction wherein the enzyme(s) have the capability to degrade extracellular matrix components within the obstruction thereby restoring the normal flow of transported fluid through the conduit. The invention also includes prophylactically dilating a section of conduit to minimize the risk of obstruction formation. The invention further includes methods for prolonging patency of hemodialysis access. |
| US08524215B2 |
Absorbable PEG-based hydrogels
An absorbable PEG-based hydrogel prepared from a multi-arm-PEG-vinylsulfone having about 3 to about 8 arms and a multi-arm-PEG-R-sulfhydryl having about 3 to about 8 arms; where R is defined as an ester linkage, such as carboxylate ester, lactate ester, and isobutyrate ester have been disclosed. Additionally, sustained release compositions that are prepared from an absorbable PEG-based hydrogel and a protein have been disclosed which provide sustained release of proteins and peptides. |
| US08524213B2 |
Polymeric materials, their preparation and use
Disclosed are highly resilient and cohesive gels formed by the cross-linking of hyaluronan or hylan, their salts or derivatives thereof, using divinyl sulfone (DVS) as the cross-linking agent. Also disclosed are viscoelastic fluids containing alkylsulfone groups covalently attached to the backbone of the polymer, formed by the mono-functionalization of the cross-linking monomer DVS with hyaluronan and/or hylan. Mechanical properties such as values of hardness and cohesiveness are specified by the rheological properties of the gels. Also disclosed are methods for the preparation of such products. They have use in many applications as injectable and/or implantable devices and as drug delivery systems. |
| US08524203B2 |
Sunscreen composite particles for UVA and UVB protection
Sunscreen composite particles for UVA and UVB protection are described. The particles are substantially free of supplied UVB sunscreen and are prepared with a UVA sunscreen suitable to undergo keto-enol tautomerization. |
| US08524202B2 |
Tooth whitening compositions and methods
Non-cytotoxic compositions for tooth whitening are disclosed. Methods of their use are also provided. |
| US08524197B2 |
Chewable antiplaque confectionery dental composition
A chewable confectionery dental composition delivering to the mouth a unit dose of a plaque reducing enzyme the composition comprising an enzyme and a non-cariogenic sweetener, the enzyme being incorporated in the composition at a temperature less than about 80° C. |
| US08524185B2 |
Integrated SCR and AMOx catalyst systems
Catalysts, methods of preparing catalyst, and methods for treating exhaust gas streams are described. In one or more embodiments, a catalyst system includes an upstream zone effective to catalyze the conversion of a mixture of NOx and NH3 to N2, and a downstream zone effective for the conversion of ammonia to N2 in the presence or absence of NOx. In an embodiment, a method for preparing a catalyst system includes: first coating one end of a substrate along at least 5% of its length with an undercoat washcoat layer containing a material composition effective to catalyze the removal of ammonia; second coating with an overcoat layer containing a material composition effective to catalyze the conversion of a mixture of NOx and NH3 to N2. A method for treating the exhaust gas stream is provided, which includes injecting ammonia or an ammonia precursor into an exhaust gas stream of a vehicle, passing the engine exhaust gas stream containing NOx and NH3 through the upstream zone of a catalyst system to remove NOx and then passing the exhaust gas stream through the downstream zone of the catalyst system to remove NH3, as well as other oxidizable species such as hydrocarbons and CO. |
| US08524184B2 |
Sulfur recovery plant tail gas treatment process
A process for the removal of hydrogen sulfide from a gas stream in which the gas stream is first passed through a Claus unit operating at a sub-stoichiometric ratio (H2S:SO2) of greater than 2:1 to produce a tail gas stream comprising less than 2000 vppm SO2. This tail gas stream is then treated to increase the sulfur recovery to at least 99.5% by first directly cooling the tail gas stream by contact with water as a coolant, followed by contacting the gas stream with a circulating stream of a dilute, absorbent solution of a severely sterically hindered secondary aminoether alcohol to further cool the gas stream, and then removing the H2S from the stream using a stronger absorbent solution of a severely sterically hindered secondary aminoether alcohol. |
| US08524182B2 |
Catalyzed soot filter with layered design
Disclosed is a catalyzed soot filter with layered design wherein the first coating of the filter comprises an oxidation catalyst comprising platinum (Pt) and optionally palladium (Pd), wherein the second coating of the filter comprises an oxidation catalyst comprising Pd and optionally Pt, wherein the Pt concentration in the second coating is lower than the Pt concentration in the first coating, and wherein the weight ratio of Pt:Pd in the second coating is in the range of from 1:1 to 0:1; and wherein the first coating and the second coating are present on the wall flow substrate at a coating loading ratio in the range of from 0.25 to 3, calculated as ratio of the loading of the first coating (in g/inch3 (g/(2.54 cm)3)): loading of the second coating (in g/inch3 (g/(2.54 cm)3)). |
| US08524181B2 |
Sensor-integrated device
The invention relates to a device for the qualitative and/or quantitative determination of at least one component of a chemically reducible gas mixture, an exhaust gas catalytic converter utilizing such a device, a vehicle including such a catalytic converter, a process for preparing such a device, a process for monitoring the NOx emissions of a vehicle, and the use of such a device. |
| US08524180B2 |
Process for minimising the emission of particular matter from marine diesel engines
The invention provides a process for minimizing the emission of particulate matter and precursors thereof from a flue gas stream of an engine comprising particulate matter and precursors thereof and at least one gaseous component. The process includes the steps of obtaining a flue gas stream of an engine comprising particulate matter and precursors thereof; increasing the moisture content of the stream by contacting it with a first aqueous medium in an amount and at a temperature at which at least 50% of the water content of the first aqueous medium is evaporated; whereby a moisture laden gas stream, optionally containing suspension droplets, is formed; cooling the moisture laden gas stream whereby suspension droplets are formed; and applying a centrifugal force to the moisture laden gas stream and to the suspension droplets to effect the swirling thereof, whereby a treated gaseous stream and an aqueous stream are formed. |
| US08524177B2 |
Process for purifying zinc oxide
A process for separating zinc from a feedstock containing a mixture of metals and metal compounds. The process includes leaching a zinc-containing feedstock with a concentrated basic solution, optionally diluting the slurry with an amount of water sufficient to reduce the viscosity of the slurry thereby facilitating separation of a pregnant liquor containing dissolved zinc from insoluble materials, separating the insoluble materials from the pregnant liquor, and precipitating zinc oxide from the pregnant liquor by adding an anti-solvent to the pregnant liquor. The described process also provides for recycling of the basic solution and the anti-solvent. |
| US08524172B2 |
Automatic calibration of a staining device
A sensor device (45) for calibrating a staining device (20) has a coupling unit (46) which is configured to be attachable to a transport device (22) of the staining device (20). A sensor unit (48) of the sensor device (45) is adapted to detect the presence of components of the staining device (20). |
| US08524170B2 |
Pipette and sealing tip
A sealing pipette tip includes features to seal the tip directly against the piston in an air displacement pipette, avoiding the need for a piston seal within the pipette. This configuration reduces potential points of failure, allows the pipette-tip interface to be optimized, and improves liquid handling characteristics of the pipette. |
| US08524166B2 |
Stent and delivery system with reduced chemical degradation including a Chitooligosaccharide
Stents and delivery systems with reduced chemical degradation and methods of sterilizing the same are disclosed. |
| US08524165B2 |
Pipe reactor and plant for manufacturing of especially urea ammonium sulphate
A pipe reactor, especially for production of UAS, includes a tubular body and a reactor head, wherein the reactor head has a device for axial injection of acid, a device for injection of ammonia, a device for supply of urea and a reaction chamber, where acid and ammonia can react before coming into contact with urea. |
| US08524162B2 |
Plasma reaction, apparatus for decreasing NOx by occlusion catalyst using the same
A plasma reaction apparatus and method applied to reformation of fuel by generating and using rotating arc plasma in a furnace, the chemical treatment of a persistent gas, and the apparatus for decreasing NOx by an occlusion catalyst. A raw material for a reaction is allowed to flow into the furnace through a hole, causing it to flow within the furnace in a continuous swirl. Furthermore, an expanded plasma reaction zone is provided by a wide area chamber which is formed on an upper part of the furnace and has a greater width than that of a lower part of the furnace, and thus a plasma being generated can be expanded by the expanded plasma zone and delayed from flowing out of the furnace by corners of the wide area chamber that is spaced from a plasma inducing electrode therein. |
| US08524160B2 |
Catalyst separation system
A catalyst separation system is provided with: a reactor where hydrocarbons are synthesized by a chemical reaction of a synthesis gas including carbon monoxide gas and hydrogen gas as main components, and a catalyst slurry having solid catalyst particles suspended in a liquid; filters which separate the hydrocarbons and the catalyst slurry; and a gas-liquid separator which separates the liquid hydrocarbons flowing out of the filter into gas hydrocarbons and liquid hydrocarbons. |
| US08524158B2 |
Wearable chemical dispenser with useful life indicator
Wearable devices for dispensing insect repellents, fragrances, and/or other chemicals along the outside of the clothing of a human are disclosed. The devices are of the type that are clipped onto a belt or the like, and use a powered fan to dispense active. Air flow is directed through a substrate and adjacent to a useful life indicator to improve reliability of the useful life indicator. |
| US08524155B1 |
Virus and particulate separation from solution
An improved system for collecting, detecting, and classifying submicron-sized particles in a sample comprising an Integrated Virus Detection System (IVDS) of the type wherein the detecting means includes a differential mobility analyzer (DMA) and condensation particle counter (CPC), the improvement comprising positioning an aerosol collector or an electrostatic collector between the differential mobility analyzer and the condensation particle counter wherein submicron-sized particles from the environmental sample are collected for further analysis. |
| US08524154B2 |
System and method for pseudo-continuous measurement of metabolite concentrations in a mammalian body
A metabolite monitoring system comprising a microdialysis probe including a semi-permeable membrane and a probe flow path passing from an inlet through a sensing volume adjacent to said semi-permeable membrane to an outlet, a fluid delivery device for delivering dialysate to said inlet; and a metabolite monitoring system associated with said outlet for monitoring a concentration of at least one metabolite in said dialysate from said microdialysis probe, wherein said fluid delivery device is configured to deliver a pulsed flow of said dialysate to said inlet. |
| US08524153B2 |
Quality control system
In a clinical laboratory of a hospital, an enormous amount of effort has been required to maintain the quality of an analyzer, standard solution and control samples. An object of the present invention is to provide a control method for controlling a clinical laboratory with reduced cost, and a control apparatus using the same.In order to control data of an analyzer, standard solution, and a control sample, a support center is connected to each analyzer located in each hospital through a network line. Various kinds of analysis parameters and the result of measurements are exchanged so as to provide each clinical laboratory with a control situation in real time. |
| US08524152B2 |
Systems and methods for enhancing rates of in situ carbonation of peridotite
Methods and systems for enhancing rates of in situ carbonation of peridotite are disclosed. In some embodiments, the methods and systems include the following: fracturing a volume of peridotite in situ; heating the volume of peridotite in situ; injecting carbon dioxide into the volume of peridotite in situ; and forming carbonate in situ with the volume of peridotite and the carbon dioxide. |
| US08524149B2 |
Nickel base wrought alloy
A nickel base alloy includes: by mass, 0.001 to 0.1% of carbon; 12 to 23% of chromium; 15 to 25% of cobalt; 3.5 to 5.0% of aluminum; 4 to 12% of molybdenum; 0.1 to 7.0% of tungsten; and a total amount of Ti, Ta and Nb being not more than 0.5%. A parameter Ps represented by a formula (1) shown below is 0.6 to 1.6, Ps=−7×[C]−0.1×[Mo]+0.5×[Al] (1) where [C] indicates an amount of carbon; [Mo] indicates an amount of molybdenum; and [Al] indicates an amount of aluminum, by mass percent. |
| US08524148B2 |
Method of integrating therapeutic agent into a bioerodible medical device
A method of making a medical device which is at least partially bio-erodible and which exhibits controlled elution of therapeutic agent. |
| US08524144B2 |
Method for enhanced fiber bundle dispersion with a divergent fiber draw unit
A method and associated apparatus for melt extruding a nonwoven web includes providing a plurality of fibers from an extrusion device. The fibers are conveyed through a diverging profile portion of a fiber drawing unit (FDU) that causes the fibers to spread and expand in the machine direction within the FDU. The fibers are then conveyed through a diverging diffusion chamber spaced from the outlet of the FDU to reduce the velocity of the fibers and further spread the fibers in the machine direction. The fibers may be subjected to an applied electrostatic charge in either the diffusion chamber or the FDU. From the outlet of the diffusion chamber, the fibers are laid onto a forming surface as a nonwoven web. |
| US08524137B2 |
Injection molded article and method for the manufacture thereof
Articles injection molded from colored poly(arylene ether) compositions can exhibit an esthetic defect known as black rings. The black rings can be reduced or eliminated when the poly(arylene ether) composition includes about 50 to about 70 weight percent of a poly(arylene ether), about 12 to about 30 weight percent of a rubber-modified polystyrene, about 5 to about 25 weight percent of an organophosphate ester flame retardant, and a first colorant and a second colorant, wherein the total amount of all colorants is about 0.3 to about 1 weight percent. |
| US08524135B2 |
Mold assembly employing fluid heating
A mold assembly for manufacturing concrete blocks in an automated dry-cast block machine. The mold assembly includes a plurality of liner plates which together form a mold cavity, wherein at least one of the liner plates includes an internal network of shafts which is configured to receive and provide a flow path for heated fluid to pass through to heat the at least one liner plate. |
| US08524134B2 |
Method of molding polymeric materials to impart a desired texture thereto
A method of molding a polymeric material to create a desired texture therein using an alumina mold having a plurality of cylindrical pores disposed therein, the method comprising the steps of: a) providing a porous alumina master having a plurality of cylindrical pores dispersed therein, said plurality of cylindrical pores corresponding to projections to be imparted to a surface of a film; disposing a polymeric material between a film and the porous alumina master; and c) applying mechanical pressure to roll the porous alumina master into the polymeric material, wherein the texture imparted to the polymeric molding material comprises projections corresponding to the cylindrical pores of the porous alumina master. A release agent is applied to the porous alumina master prior to disposing the polymeric molding material between the porous alumina master and the film. |
| US08524132B2 |
Method of fabricating an intraluminal scaffold with an enlarged portion
Devices and methods for treating veins and venous conditions, such as chronic cerebrospinal venous insufficiency, are provided. In one aspect, the disclosed subject matter provides an intraluminal scaffold having a generally tubular body with a lumen defined therethrough, the tubular body having a compressed condition for delivery and an expanded condition for implant within a vessel having a distended portion, at least a length of the tubular body configured to form an enlarged portion in the expanded condition to engage a wall of the distended portion of the vessel. Methods for fabricating and using the scaffold, methods for remodeling a vein, and methods of deploying a medical device in a vessel without negatively impacting the function of a valve of the vessel, are also provided. |
| US08524128B2 |
Method for production of porous ceramic material
The invention provides a method of producing a porous ceramics material. The method comprises preparing a slurry by dispersing a ceramics raw material in a medium, filling the slurry in a container, inserting the container in a given direction into a cooling medium having a temperature not higher than the freezing point of the slurry such that the slurry freezes unidirectionally from one end side, drying the frozen slurry to give a green body, and firing the green body. |
| US08524120B2 |
Single conductive pellets of long glass fiber reinforced thermoplastic resin and manufacturing method thereof
Single pellets of a thermoplastic resin containing long glass fibers and a conductive filler are set forth that enable molded articles made from these pellets to exhibit conductivity and, at the same time, high mechanical properties. These pellets have mechanical properties that are substantially equivalent to non-conductive pellets of a thermoplastic resin containing same loading of long glass and provide conductivity that is substantially equivalent to articles obtained by blending two kinds of pellets, one pellet having a conductive filler and the other pellet one containing long glass fibers. The pellets include a thermoplastic resin, a long fiber reinforcing filler and a conductive additive dispersed in the pellet. |
| US08524119B2 |
Catalyst for preparing synthesis gas from natural gas and carbon dioxide, and preparation method thereof
Disclosed are a catalyst for preparing synthesis gas from natural gas and carbon dioxide, and a method for preparing the same. More particularly, a combined reforming process is performed as an economical way of using carbon dioxide, wherein steam reforming of natural gas is carried out simultaneously with carbon dioxide reforming of methane in such a manner that a predetermined ratio of carbon monoxide/carbon dioxide/hydrogen (H2/(2CO+3CO2)=0.85-1.15) is maintained. In this manner, the catalyst is used to prepare synthesis gas suitable for methanol synthesis and Fischer-Tropsch synthesis. Disclosed also is a method for preparing synthesis gas on a specific catalyst consisting of Ni/Ce/MgAlOx or Ni/Ce-Zr/MgAlOx. The catalyst is inhibited from deactivation caused by generation of cokes during the reaction as well as deactivation caused by reoxidation of nickel with water added during the reaction. Therefore, the catalyst shows excellent activity as compared to other catalysts for use in combined reforming. |
| US08524118B2 |
Nitride phosphor, method of preparing the same, and white light-emitting device using the same
A nitride phosphor represented by Formula 1: M1a-zCezM2b-xM3xNc-yOy, Formula 1 wherein M1 is at least one metal selected from the group consisting of Sc3+, Y3+, Lu3+, La3+, Pr3+, Sm3+, Gd3+, Tb3+, Yb3+, Dy3+, Eu3+, and Bi3+, M2 is at least one metal selected from the group consisting of Si4+ and Ge4+, M3 is at least one metal selected from the group consisting of Al3+, B3+, and Ga3+, a is equal to or greater than about 1.8 and equal to or less than about 2.2, b is equal to or greater than about 3.8 and equal to or less than about 4.2, c is equal to or greater than about 6.7 and equal to or less than about 7.3, x is equal to or greater than about 0.7 and less than about 3, y is equal to or greater than 0 and less than about 3, and z is greater than 0 and less than about 1. |
| US08524117B2 |
Liquid crystalline medium
The invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy, which contains at least one compound of the formula I and at least one compound of the formula II in which R1, R2, R3, R4, ring A, Z1, Z2 and m are as defined in Claim 1, and to the use thereof for an active-matrix display based on the ECB, VA, PS-VA, FFS, PALO or IPS effect. |
| US08524113B2 |
Anode material of lithium-ion secondary battery and preparation method thereof
In an anode material of a lithium-ion secondary battery and its preparation method, a natural graphite, an artificial graphite or both are mixed to form a graphite powder, and the graphite powder is mixed with a resin of a high hard carbon content and processed by a mist spray drying process, and finally added or coated with a special resin material after a carburizing heat treatment takes place to prepare a graphite composite of the anode material of the lithium-ion secondary battery and achieve a smaller surface area of an anode graphite composite of the battery and extended cycle life and capacity. |
| US08524111B2 |
CMP abrasive slurry for polishing insulation film, polishing method, and semiconductor electronic part polished by the polishing method
The present invention provides a CMP abrasive slurry for polishing insulation film, that allow efficiently and high-speed polishing of insulation films such as SiO2 film and SiOC film in the CMP method of flattening an interlayer insulation film, a BPSG film, an insulation film for shallow trench isolation, or a wiring-insulating film layer, a polishing method by using the abrasive slurry, and a semiconductor electronic part polished by the polishing method. A CMP abrasive slurry for polishing insulation film containing cerium oxide particles, a dispersant, a water-soluble polymer having amino groups on the side chains and water, a polishing method by using the CMP abrasive slurry, and a semiconductor electronic part polished by the polishing method. |
| US08524107B2 |
Magnetocaloric structure
A magnetocaloric structure includes a magnetocaloric material and at least one protective layer. The magnetocaloric material has bar type or plank type. The protective layer is disposed on the magnetocaloric material. |
| US08524103B2 |
Method for manufacturing susceptor
A method for manufacturing a susceptor includes: forming a concave pattern in a surface of a substrate to be processed; applying a SiC paste containing a SiC powder and a sintering agent to the surface of the substrate to be processed to fill the concave pattern to form a SiC coating layer; laminating a SiC substrate on the SiC coating layer; and firing the SiC coating layer to form a SiC layer having at least one convex section on the surface of the SiC substrate. |
| US08524102B2 |
Ashing method and ashing device
An ashing device and ashing method that can positively remove resist from a wafer while preventing degradation of the film material properties of exposed porous Low-K film on the wafer. The ashing device of the present invention introduces a gas to a dielectric plasma generating chamber 14, excites said gas to generate a plasma, and performs plasma processing using said gas plasma on a processing work S in use of a Low-K film. The ashing gas introduced from a gas regulator 20 is an inert gas to which H2 has been added. The configuration is formed so that plasma is generated from the gas blend, and the resist is removed by the hydrogen radicals generated. |
| US08524099B2 |
Methods for accessing a process chamber using a dual zone gas injector with improved optical access
Methods for processing events occurring in a process chamber are provided. In one method, an operation includes carrying gas and receiving an optical signal from the process chamber to an analysis tool that operates in response to the optical signal having a signal-to-noise ratio (SNR) for process analysis. And, dividing the carried gas and optical signal into a plurality of separate gas and optical signals between the process chamber and the analysis tool. The dividing is configured through separate apertures so that the apertures collectively maintain the SNR of the optical signal received at the tool. Methods provide a septum in a second bore dividing the second bore into apertures configured to reduce etching of and deposition on the optical access window and to maintain the desired SNR at the diagnostic end point. |
| US08524098B2 |
Method for forming nano size turf on transparent polymer films used in solar cells, and method for enhancing transmittance of transparent polymer films of solar cells
The method for forming nano size turfs on a surface of a transparent polymer film used in a solar cell is disclosed, which comprises a first step for attaching a transparent polymer film on a glass, a second step for installing the glass prepared in the first step on an upper side of the electrodes provided in the interior of a chamber and forming either a vacuum environment or an atmospheric environment, and a third step for supplying an electric power to the electrodes under the environment formed in the second step, etching the transparent polymer film attached on the surface of the glass and forming nano size turfs in circular cone shapes. |
| US08524096B2 |
Method of manufacturing liquid crystal display device
In one embodiment, a first substrate including first and second array regions are prepared. The first and second array regions respectively include first and second active areas. A peripheral seal material having an air intake opening is arranged outside the first and second array regions. A second substrate is arranged on the surface of the first substrate in which the first and second seal materials and peripheral seal material are formed in a vacuum chamber under vacuum state. Atmosphere is introduced into the vacuum chamber and a space between the first and second seal materials from the air intake opening. Then, a pressure is applied to the first and second substrates by pressure difference between the atmospheric pressure of circumference which surrounds the first substrate and second substrate, and the atmospheric pressure of the space between the first substrate and second substrate. |
| US08524086B2 |
Fluid purification system
Certain disclosed embodiments concern systems and methods of preparing dialysate for use in a home dialysis system that is compact and light-weight relative to existing systems and consumes relatively low amounts of energy. The method includes coupling a household water stream to a dialysis system; filtering the water stream; heating the water stream to at least about 138 degrees Celsius in a non-batch process to produce a heated water stream; maintaining the heated water stream at or above at least about 138 degrees Celsius for at least about two seconds; cooling the heated water stream to produce a cooled water stream; ultrafiltering the cooled water stream; and mixing dialysate components into the cooled water stream in a non-batch process. |
| US08524085B2 |
Sewage composting method
A method for creating Class A compost for sale to the public from waste products, especially municipal sewage, involving lower expense and improved versatility over prior methods. |
| US08524083B2 |
Beer filter
A filter device and a method for the filtration of beer, where, for an improved and simplified filtration, the filter includes a nonfiltrate chamber having a nonfiltrate inlet and a nonfiltrate outlet, wherein the nonfiltrate flows into the nonfiltrate chamber substantially tangentially to the walls thereof, and the bottom of the nonfiltrate chamber is constructed at least partially as a filter. The filter also includes a filtrate chamber underneath the bottom, and a filtrate outlet. |
| US08524081B2 |
Separation modules including media for separating water-hydrocarbon emulsions having low interfacial tensions
Separation media, separation modules and methods are provided for separating water from a water and hydrocarbon emulsion and include a fibrous nonwoven coalescence layer for receiving the water and hydrocarbon emulsion and coalescing the water present therein as a discontinuous phase to achieve coalesced water droplets having a size of 1 mm or greater, and a fibrous nonwoven drop retention layer downstream of the coalescence layer having a high BET surface area of at least 90 m2/g or greater sufficient to retain the size of the coalesced water droplets to allow separation thereof from the hydrocarbon. |
| US08524075B1 |
Backwashing fluid filter assembly
A fluid pressure vessel has a filter cartridge with spaced headers positioning cylindrical pleated filter media. The headers form an inlet chamber communicating with the inlet upstream side of the filter media and an isolated outlet chamber communicating with the downstream side of the filter media. A hollow piston with a toothed periphery having a circumferential slot is positioned closely adjacent the upstream side of the filter media. The piston hollow communicates with a drain chamber isolated from the inlet and outlet chambers. Upon opening of the drain chamber to atmospheric pressure, the pressure in the piston hollow and slot causes a lower pressure in a localized area of the media and back flushing of trapped material on the upstream side of the media to the drain chamber. An actuator is connected to selectively progressively move the piston and slot along the entire surface of the media. |
| US08524072B2 |
Catalyst and method for alkli-free purification of oil raw materials from mercaptans
A catalyst for alkali-free purification of oil raw material, consisting of a metalocomplex selected from the group consisting of a solid metalocomplex and a liquid metalocomplex with a general formula (CuIICl)2O(L1)2-4(L2)1-4, where L1 is amino alcohol L2 is acetonitrol or single atom alcohol. |
| US08524071B2 |
Process for adsorption of sulfur compounds from hydrocarbon streams
The present invention provides a high capacity adsorbent for removing sulfur from hydrocarbon streams. The adsorbent comprises a composite material containing particles of a nickel phosphide complex NixP. The adsorbent is utilized in a sulfur removal process that does not require added hydrogen, and run at relatively low temperatures ranging from about 150° C. to about 400° C. The process of this invention enables “ultra-deep” desulfurization down to levels of about 1 ppm and less. |
| US08524070B2 |
Method for processing hydrocarbon pyrolysis effluent
A method and apparatus are disclosed for treating the effluent from a hydrocarbon pyrolysis unit employing a small primary fractionator, i.e., a rectifier. The method comprises cooling the gaseous effluent, e.g., by direct quench and/or at least one primary heat exchanger, and then cooling the gaseous effluent to a temperature at which tar, formed by reactions among constituents of the effluent, condenses, e.g., in a secondary exchanger. The resulting mixed gaseous and liquid effluent is passed through a rectifier, to cleanly separate quench oil from the gaseous effluent comprising a pyrolysis gasoline fraction, whose boiling point can be lowered as a result of the rectifier treatment. The effluent is then cooled to condense a liquid effluent comprising pyrolysis gasoline and water condensed from steam, which fractions are separated in a distillate drum. The cooled gaseous effluent is directed to a recovery train to recover light olefins. At least a portion of the pyrolysis gasoline-containing fraction can be recycled to the rectifier to enhance separation of the quench oil from the pyrolysis gasoline fraction. |
| US08524068B2 |
Low-rate electrochemical etch of thin film metals and alloys
Embodiments of the present invention include systems and methods for low-rate electrochemical (wet) etch that use a net cathodic current or potential. In particular, some embodiments achieve controlled etch rates of less than 0.1 nm/s by applying a small net cathodic current to a substrate as the substrate is submerged in an aqueous electrolyte. Depending on the embodiment, the aqueous electrolyte utilized may comprise the same type of cations as the material being etched from the substrate. Some embodiments are useful in etching thin film metals and alloys and fabrication of magnetic head transducer wafers. |
| US08524067B2 |
Electrochemical method of producing nano-scaled graphene platelets
A method of producing nano-scaled graphene platelets with an average thickness smaller than 30 nm from a layered graphite material. The method comprises (a) forming a carboxylic acid-intercalated graphite compound by an electrochemical reaction; (b) exposing the intercalated graphite compound to a thermal shock to produce exfoliated graphite; and (c) subjecting the exfoliated graphite to a mechanical shearing treatment to produce the nano-scaled graphene platelets. Preferred carboxylic acids are formic acid and acetic acid. The exfoliation step in the instant invention does not involve the evolution of undesirable species, such as NOx and SOx, which are common by-products of exfoliating conventional sulfuric or nitric acid-intercalated graphite compounds. The nano-scaled platelets are candidate reinforcement fillers for polymer nanocomposites. Nano-scaled graphene platelets are much lower-cost alternatives to carbon nano-tubes or carbon nano-fibers. |
| US08524065B2 |
Systems and methods for electrocoating a part
Embodiments of systems and methods for electrocoating a part are presented herein. According to one embodiment, an electrocoating system comprises a tank, a pump in fluid communication with the tank, and an external anode positioned outside of the tank. The external anode is a substantially membrane-free metal pipe configured to provide an electric charge to a fluid for electrocoating a part. The system may further comprise one or more internal nozzles positioned inside of the tank to direct an electrically charged fluid from the pump into the tank for electrocoating a part. In addition, the system may further comprise one or more external nozzles positionable outside of the tank to direct an electrically charged fluid from the pump to one or more selected areas of a part positioned for electrocoating outside of the tank. |
| US08524064B2 |
Three dimensional microelectrode system for dielectrophoresis
A dielectrophoresis apparatus for separating particles from a sample, including an apparatus body; a dielectrophoresis channel in the apparatus body, the dielectrophoresis channel having a central axis, a bottom, a top, a first side, and a second side; a first mesa projecting into the dielectrophoresis channel from the bottom and extending from the first side across the dielectrophoresis channel to the second side, the first mesa extending at an angle to the central axis of the dielectrophoresis channel; a first electrode extending along the first mesa; a second mesa projecting into the dielectrophoresis channel from the bottom and extending from the first side across the dielectrophoresis channel to the second side, the second mesa extending at an angle to the central axis of the dielectrophoresis channel; a space between at least one of the first electrode and the second side or the second electrode and the second side; and a gap between the first electrode and the second electrode. |
| US08524061B2 |
On-chip hybridization coupled with ITP based purification for fast sequence specific identification
Isotachophoresis (ITP) can be employed to simultaneously focus the target and ligand of an assay into the same ITP focus zone. The target and ligand can bind to each other in the ITP focus zone, and then the resulting bound complex can be detected (e.g., by fluorescence). The sensitivity of this approach can be greatly increased by the enhanced concentration of both target and ligand that ITP provides in the focus zone. Since ITP can be performed quickly, the resulting assay is both rapid and sensitive. Markers of bacterial urinary tract infections have been experimentally detected at clinically relevant concentrations with this approach. MicroRNA sequences have also been profiled with this approach, which is clinically relevant because MicroRNA is expected to provide useful markers for disease. In one experiment, miR-122 in human kidney and liver was detected and quantified. |
| US08524059B2 |
Apparatus and method for adjusting pH of solution
A pH adjusting apparatus includes an electrolytic chip receiving a solution, an electrolytic chip loading station receiving the electrolytic chip, an input unit inputting electrolysis conditions, a control unit receiving the electrolysis conditions and controlling electrolysis performed in the electrolytic chip, and a display unit displaying the electrolysis conditions and a progress of the electrolysis. Thus, the pH of a solution can be adjusted easily and accurately, by precisely controlling a constant current, a constant voltage, and current and voltage application times, thereby enabling useful application in various biological assays such as cell lysis. Furthermore, the pH adjusting apparatus has small size and weight and can be operated for a long time after charging once due to low power consumption. |
| US08524055B2 |
Method for measuring blood components and biosensor and measuring instrument for use therein
The present invention provides a method of measuring a component in blood, by which the amounts of blood cells and an interfering substance can be measured with high accuracy and high reliability and the amount of the component can be corrected accurately based on the amounts of the blood cells and the interfering substance. In a sensor for measuring a blood component, a first working electrode 13 measures a current that flows during a redox reaction of a blood component, a second working electrode 17 measures the amount of blood cells, and a third working electrode 12 measures the amount of an interfering substance. Next, based on the measurement results, the amount of the blood component to be measured is corrected. Thus, more accurate and precise measurement of the amount of the blood component can be realized. |
| US08524054B2 |
Loading device and sputtering device using same
A sputtering device includes a main body and a loading device received in the main body. The main body includes a top portion, a bottom portion, and a sidewall connected between the top portion and the bottom portion, an upper bearing mounted on the top portion, and a lower bearing mounted on the bottom portion. The loading device includes an outer frame, an inner frame received in the outer frame, and a gear device arranged between the outer frame and the in inner frame. The outer frame is rotatably connected to the upper bearing and includes a plurality of first rods arranged in a first circle. The inner frame is rotatably connected to the lower bearing and includes a plurality of second rods arranged in a second circle. The gear device is configured for bringing the outer frame and the inner frame to rotate in opposite directions. |
| US08524053B2 |
Compositions of corrosion-resistant Fe-based amorphous metals suitable for producing thermal spray coatings
A method of coating a surface comprising providing a source of amorphous metal that contains manganese (1 to 3 atomic %), yttrium (0.1 to 10 atomic %), and silicon (0.3 to 3.1 atomic %) in the range of composition given in parentheses; and that contains the following elements in the specified range of composition given in parentheses: chromium (15 to 20 atomic %), molybdenum (2 to 15 atomic %), tungsten (1 to 3 atomic %), boron (5 to 16 atomic %), carbon (3 to 16 atomic %), and the balance iron; and applying said amorphous metal to the surface by a spray. |
| US08524050B2 |
Stainless steel separator for fuel cell having M/MNx and MOyNz layer and method for manufacturing the same
Disclosed herein is a method of manufacturing a stainless steel separator for a fuel cell. The stainless steel separator includes a stainless steel sheet, a first coating layer comprising metal/metal nitride films (M/MNx) (0.5≦x≦1) on a surface of the stainless steel sheet, and a second coating layer comprising a metal oxynitride film (MOyNz) (0.05≦y≦2, 0.25≦z≦1.0). |
| US08524047B2 |
Method of dehydrating tolylenediamine and dehydrator
A method of dehydrating tolylenediamine which includes subjecting tolylenediamine having a water content of 5-40 wt. % to first-stage distillation at a vacuum of 13-101.3 kPa and subjecting the bottoms from the first-stage distillation to second-stage distillation at a vacuum lower than 13kPa. |
| US08524045B2 |
Systems for purifying silane
Processes and systems for purifying silane-containing streams are disclosed with relatively less silane being lost in impurity streams by use of distillation and/or condensation operations. |
| US08524043B2 |
System for producing high quality gasoline by catalytic hydrocarbon recombination
This invention relates to a system for the preparation of a high quality gasoline through the recombination of catalytic hydrocarbon and its process. The characteristics are as follows: the upper part of the fractionator is connected with light petrol hydrogenation unit through the light petrol pipeline. The lower part of the fractionator is connected with the extractor through the heavy petrol pipeline. The upper part of the extractor directly extracts the product through the pipeline and the lower part of the extractor is connected to the light petrol pipeline behind the light petrol hydrogenation unit. Compared with the prior art, this invention has the following advantages: the volume of used catalyst is greatly reduced. In addition, the sulfur reduction and olefin reduction effect are remarkable by using the hydrogenation units with special catalysts and parameters regarding different petrol fractions. |
| US08524042B2 |
Method of treating paper forming wire surface
A method for inhibiting resinous and sticky substances from filling or forming deposits on or within papermaking forming wire, by applying to said wire an effective inhibiting amount of a composition comprising at least one cationic agent selected from the group consisting of (a) cationic polyureas, (b) hydrophobically modified cationic polymers, (c) alkylammonium or/and alkylimidazolium salts, and optionally at least one nonionic amphiphilic copolymer selected from (i) hydrophobically modified polyethylene glycols], (ii) hydrophobically modified cellulose ethers, (iii) copolymers of vinyl alcohol and vinyl alkonate, (iv) polyoxyalkylene block copolymers, and (v) hydrophilically modified polydimethylsiloxanes. |
| US08524041B2 |
Method for forming a fibrous media
Embodiments for methods and apparatuses for forming a nonwoven web are described herein. In one embodiment, an apparatus includes one or more sources configured to dispense a first fluid flow stream comprising a fiber and a second fluid flow stream also comprising a fiber. The apparatus also includes a mixing partition downstream from the one or more sources, where the mixing partition is positioned between the first and second flow streams from the one or more sources. The mixing partition defines one or more openings that permit fluid communication between the two flow streams. The apparatus also includes a receiving region situated downstream from the one or more sources and designed to receive at least a combined flow stream and form a nonwoven web by collecting fiber from the combined flow stream. |
| US08524039B2 |
Papermaking mould for producing two-stage watermarks and method for producing the same
A screen for producing two-level watermarks is produced by completely closing part of the screen with a viscous sealing compound, which is subsequently cured actively or passively. At the thus closed partial areas of the screen, paper deposit is hindered during papermaking so that the finished paper appears light in transmission in the areas. A mask is used for exactly positioning the sealing compound in the partial areas of the screen and/or for curing the sealing compound only in the given partial areas, whereby in the latter case the uncured areas of the sealing compound are washed out. |
| US08524037B2 |
Continuous digestion of chip blends containing a western red cedar chip furnish
A process is provided for delignifying lignocellulosic material, including feeding a lignocellulosic blend comprising a Western Red Cedar (WRC) chip furnish and a second lignocellulosic material into an aqueous alkaline pulping solution at the feed end of a digester to produce a lignocellulosic mass. The second lignocellulosic material is provided in a proportion that increases the density of the mass to enable the mass to move through the digester while minimizing production effects associated with low density WRC chips. The mass moves through the digester to produce a pulp that may be bleached. |
| US08524035B2 |
Method and apparatus for conformable polishing
Methods and apparatus provide for a conformable polishing head for uniformly polishing a workpiece. The polishing head includes an elastic polishing pad mounted on an elastic membrane that seals a cavity in the polishing head. The cavity is pressurized to expand the membrane and press the polishing pad down on the top surface of the workpiece, such that the polishing pad conforms to the surface and applies a substantially uniform pressure distribution across the workpiece and thereby uniformly removes material across high and low spots on the workpiece. |
| US08524034B2 |
Hydrogen peroxide complexes and their use in the cure system of anaerobic adhesives
Provided is a complex of hydrogen peroxide and at least one compound represented by Formula I: wherein X is: —C(R3)3, —C≡C(R3), —O(R3), —N(R3)2, or —S(R3); and R1, R2, and R3 are each independently selected from H, alkyl, alkenyl, alkynyl, aralkyl, aryl, heteroaryl heteroarylalkyl, heterocyclyl, and cycloalkyl, or R2 and an R3 are optionally taken together to form an alicyclic ring. Also provided are anaerobic cure systems and curable compositions employing the complexes described herein. |
| US08524033B2 |
Coated wood composite and production method thereof
To provide: a coated wood composite having surface properties such as transparency, smoothness, gloss, uniformity, and depth, and excellent in various physical properties such as durability and strength; and a method for producing such a coated wood composite efficiently and easily. A coated wood composite produced by placing an unsaturated polyester resin composition on a decorative veneer and heat-pressing the decorative veneer and the composition placed thereon to mold the composite, wherein the unsaturated polyester resin composition comprises: an unsaturated polyester; a polymerizable monomer; and an isocyanate component essentially including an aliphatic diisocyanate. |
| US08524032B2 |
Connecting film, and joined structure and method for producing the same
A method for producing a joined structure involving pressure-bonding a first circuit member and a second circuit member together via a connecting film while the circuit members are being heated, to thereby join the circuit members with each other, wherein the connecting film is defined and includes first and second layers wherein one of the first layer and the second layer is a conductive particle-containing organic resin layer, and the other layer is an insulating organic resin layer containing no conductive particles, and wherein the minimum melt viscosity of the conductive particle-containing organic resin layer is ten times or more greater than the minimum melt viscosity of the insulating organic resin layer. |
| US08524031B2 |
Lining method and lining installation for the production of multi-layer products
The invention relates to a lining method and a lining installation for the production of multi-layer products which are used, for example, to produce floor or wall coverings or interior trim for passenger transport vehicles, such as cars, railroad cars, ship cabins and aircraft cockpits. |
| US08524030B2 |
Fuel tank and method for reducing vapor permeation through a fuel tank
A method of reducing fuel vapor permeation through a multi-layer tank includes providing a multi-layer overlay onto at least a portion of a structural layer of the multi-layer tank. The multi-layer overlay preferably comprises at least one structural layer composed of a polymeric material that is compatible with one or more of the polymeric structural layer(s) of the multi-layer tank. The multi-layer overlay further comprises at least one barrier layer composed of a vapor barrier material resistant to hydrocarbon permeation therethrough. The multi-layer overlay may be secured to the multi-layer tank by, for example, applying a suitable amount of heat and pressure thereto or by molding the multi-layer overlay to the tank body during a tank forming process. |
| US08524029B2 |
System for mounting objects to polymeric membranes
A mounting system and method to elastically attach an object to a support structure with an elastic membrane. The elastic membrane allows the object attached thereto to elastically extend in a direction away from the support structure as force is exerted on the object. The elastic membrane includes two surface areas, the first surface area extending peripherally along a perimeter a bottom surface of the elastic membrane and a remaining second surface area. The first surface area being thermally bonded to the support structure, while the second surface area remaining separable from the support structure. |
| US08524021B2 |
In-process vision detection of flaw and FOD characteristics
An inspection system (9) includes an idler wheel (61) that is coupled to a fabrication system (8) and is in contact with a backing layer (65) of an applied material (64), A rotation sensor (63) monitors the idler wheel (61) and generates a rotational signal. A controller (24) is coupled to the rotation sensor (63) and determines a characteristic of one or more flaws and FOD (19) on a composite structure (12) in response to the rotation signal. |
| US08524007B2 |
Cleaning sheet, transfer member provided with cleaning function, and method for cleaning substrate processing apparatus
A cleaning sheet including a cleaning layer which has a microasperity shape having an arithmetic average roughness Ra of 0.05 μm or less and a maximum height Rz of 1.0 μm or less. Preferably, a substantial surface area of the cleaning layer per a flat surface of 1 mm2 is 150% or more of a substantial surface area of a silicon wafer mirror surface per a flat area of 1 mm2. The cleaning sheet may be provided on at least one surface of a transfer member so that the transfer member has a cleaning function. When the cleaning sheet or the transfer member having a cleaning function is transferred in a substrate processing apparatus in place of a substrate to be processed therein, the cleaning sheet contacts and cleans a site of the substrate processing apparatus. |
| US08524005B2 |
Heat-transfer structure and substrate processing apparatus
A heat-transfer structure which can keep a consumable component at a temperature of 225° C. or less during etching of a substrate. The heat-transfer structure is disposed in a chamber where plasma processing is performed on a wafer as the substrate under a reduced pressure. The heat-transfer structure is comprised of a focus ring having an exposed surface exposed to plasma, a susceptor and an electrostatic chuck that cool the consumable component, and a heat-transfer sheet interposed between the focus ring and the electrostatic chuck and made of a gel-like material. The ratio of hardness of the heat-transfer sheet expressed in Asker C to thermal conductivity of the heat-transfer sheet expressed in W/m·K is less than 20. |
| US08524000B2 |
Pulling assemblies for pulling a multicrystalline silicon ingot from a silicon melt
Methods for producing multicrystalline silicon ingots by use of a Czochralski-type crystal puller and pulling assemblies that include a plurality of seed crystals for pulling multicrystalline silicon ingots. |
| US08523997B2 |
Cellular phosphate ceramics and methods of manufacture and use
Embodiments of the present invention provide cellular phosphate bodies formed using specialized steps to ensure a specific strength range, and specifically a compressive strength less than 100 pounds per square inch. Further embodiments relate to uses for various phosphate ceramics as vehicle arresting systems. |
| US08523996B2 |
Method of fabricating liquid for oxide thin film
A method of fabricating a liquid for an oxide thin film is provided, which includes mixing at least two kinds of dispersoids selected from the group consisting of a Zinc compound, an Indium compound, a Gallium compound, a Tin compound and a Thallium compound, with dispersion media corresponding to the selected dispersoids to form a dispersion system, and stirring and aging the dispersion system at a predetermined temperature for a predetermined time, wherein a molar ratio of the Zinc compound to each of the Indium compound, Gallium compound, Tin compound and Thallium compound is 1:0.1 to 1:2. According to the present invention, the liquid for the oxide thin film may be fabricated by a sol-gel method making it capable of being implemented in mass production in a simple and low-cost manner as opposed to the conventional vacuum deposition method. |
| US08523995B2 |
Compositions for polymer bonding
Compositions having a compound comprising at least one alkoxy silane moiety, and at least one moiety selected from a nitrosoaromatic or a nitrosoaromatic precursor and combinations thereof; and an aqueous or water containing carrier medium are provided for use in polymer bonding. The water may allow for substantial hydrolysis of the compound. Suitable polymers may have diene or allylic functionality within the polymer chain, for example an elastomer such as a natural or synthetic rubber. The polymers may be bonded to metals or substrates with hydroxylated surfaces such as glass. The nitrosobenzene precursor may be at least one of a quinone dioxime or a quinone oxime. |
| US08523994B2 |
Method for reducing hydrogen sulfide evolution from asphalt
Hydrogen sulfide evolution from asphalt may be reduced or eliminated using an additive to act as a scavenger. Zinc oxide, when present in the form of nano-particles is an effective component is preventing or mitigating the evolution of hydrogen sulfide from asphalt. Zinc sulfonate may also be used. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 CFR 1.72(b). |
| US08523992B2 |
Magenta recording ink composition, inkjet recording method, and ink recorded matter
The present invention provides a magenta recording ink composition including at least a solid solution pigment (A) containing quinacridone, a lake pigment (B) having a xanthene structure, an aqueous solvent, and water, wherein the solid solution pigment (A) has visible light absorption peaks at wavelength ranges of from 510 nm to 530 nm and from 540 nm to 560 nm, and a mass ratio (B/A) of the lake pigment (B) to the solid solution pigment (A) falls within the range of 0.1 to 5. |
| US08523990B2 |
Ink composition, inkjet recording ink composition, ink set, ink cartridge, inkjet recording method and recorded matter
An ink composition having a suitably-adjusted hue and causing no decomposition of dyes during storage is provided. The ink composition contains a compound (a) represented by the following formula (1), an ingredient (c) and moisture-retentive agents, characterized by being from 0.1 mass % to lower than 7.0 mass % in content of the compound represented by the formula (1), 10.0 mass % or lower in content of a moisture-retentive agent having 3 or more hydroxyl groups (b) and lower than 30.0 in molar ratio of the moisture-retentive agent having 3 or more hydroxyl groups to the compound represented by the formula (1): wherein each of Ar1 and Ar2 preferably represents an aromatic heterocyclic group, each of A1 and A2 represents a hydrogen atom or a substituent, Y represents —OM or —NR1R2, M represents a hydrogen atom or a metal ion and each of R1 and R2 represents a hydrogen atom, an alkyl group, an aryl group, a heterocyclic group or the like. The ingredient (c) is at least one compound selected from C.I. Direct Yellow 59, id. 86, id. 132 or the like. |
| US08523989B2 |
Lead-free primary explosive composition
Embodiments of the present subject matter provide a compound and material that may be used as a lead-free primary explosive. An embodiment of the present subject matter provides the compound copper(I) nitrotetrazolate. Certain embodiments of the present subject matter provide methods for preparing lead-free primary explosives. The method includes: providing cuprous salt; providing water; providing 5-nitrotetrazolate salt; combining the cuprous salt, water and 5-nitrotetrazolate salt to form a mixture; and heating the mixture. The method may also include providing cuprous chloride and providing sodium 5-nitrotetrazolate. Certain embodiments of the present subject matter also provide methods for preparing copper(I) nitrotetrazolate. The method includes: providing cuprous salt; providing water; providing 5-nitrotetrazolate salt; combining the cuprous salt, water and 5-nitrotetrazolate salt to form a mixture; and heating the mixture. The method may also include providing cuprous chloride and providing sodium 5-nitrotetrazolate. |
| US08523986B2 |
Gas scrubber and use of the gas scrubber
In a gas scrubber, a gas stream containing at least one sublimed substance is brought in contact with a liquid or melt stream containing at least one thermally convertible substance, which has a lower temperature than the gas stream. For the intensive and intimate mixing of the gas stream with the liquid or melt stream, an orifice plate with a plurality of holes each surrounded by a retaining edge is provided in the upper part of the gas scrubber, and above the orifice plate inlets for the gas stream and the liquid or melt stream are provided. |
| US08523984B2 |
Water circulation systems with air stripping arrangements for municipal water tanks, ponds, and other potable bodies of water
Water circulation systems with air stripping arrangements to treat and remove undesirable disinfectant byproducts from potable water in municipal water tanks, ponds, and other bodies of water. The systems include a flotation platform, dish, draft tube, and an impeller to draw water from the depths of the tank up through the draft tube to be discharged outwardly of the dish to create a primary circulation pattern and an induced, inner or secondary circulation pattern. Each system additionally includes an air stripping arrangement positioned adjacent and about the upper portion of the draft tube and adjacent an upper portion of the secondary flow. The air stripping arrangement includes a plurality of submerged sets of air manifolds wherein pressurized air is supplied to the air manifolds and driven out of them in bubbles to create a treatment zone immediately above each set of manifolds. |
| US08523982B2 |
Separation membrane module and fuel vapor processing apparatus equipped with the same
A separation membrane module for separating a specific component from a mixture containing a plurality of components includes a plurality of separation stages each including a plurality of hollow fiber membranes arranged in parallel to each other. The separation stages are connected in series via connection portions allowing passage of the mixture. At lease one parameter relating to separation by the hollow fiber membrane or membranes in each separation stage is determined to provide effective separation throughout the separation stages. |
| US08523980B2 |
Clean water reclamation from humid air
An apparatus for water reclamation includes an inlet head for admitting warm humid ambient air, a buried pipe coupled at a first end to the inlet head and sloping downward in the ground from the first end. Water condenses as the air is cooled in the buried pipe and collects in a cistern coupled at a second end of the buried pipe. A tube coupled at a lower end near the second end of the buried pipe includes a heated element extending at least partially into the tube from an upper end of the tube. Cooled air is heated by the heated element and is expelled at the top of the tube. A heater is coupled to an upper end of the heated element. The heater may be a solar collector with a Bernoulli aperture. |
| US08523976B2 |
Metal powder
The present invention relates to a metal powder mixture that is suitable for producing sintered bodies. The powder mixture is suitable as a binder for hard metals and contains: a) at least one prealloyed powder selected from the group of iron/nickel, iron/cobalt, iron/nickel/cobalt and nickel/cobalt; b) at least one element powder selected from the group of iron, nickel and cobalt or a prealloyed powder selected from the group consisting of iron/nickel, iron/cobalt, iron/nickel/cobalt and nickel/cobalt which is different from component a). The invention also relates to a cemented hard material which uses the inventive powder mixture and a hard material powder, wherein the overall composition of the components a) and b) together contains not more than 90% by weight of cobalt and not more than 70% by weight of nickel and the iron content. |
| US08523974B2 |
Filter core for use with pleated filter cartridges
A filter core includes a tubular body that has a first end and a second end. The tubular body includes a plurality of surface features spaced longitudinally along the tubular body between the first and second ends. Each of the surface features includes a first portion for flow area and a second portion for bridging across an opening for strength. |
| US08523969B2 |
Indoor unit of air conditioner
An air filter (30) intermittently rotates by a predetermined rotation angle at each time, while being in contact with a bristle portion (51b) of a rotating brush (51). Accordingly, dust on the air filter (30) is scraped by the bristle portion (51b). The brush member (51) rotates about an axial center of a shaft (51a) at each stop of the intermittent rotation of the air filter (30), to come into contact with a cleaning brush member (52). According, dust on the brush member (51) is removed by the cleaning brush member (52). |
| US08523959B2 |
Paraffinic biologically-derived distillate fuels with bio-oxygenates for improved lubricity and methods of making same
The present invention is generally directed to methods for making fuels from biomass comprising triglyceride species, whereby the biomass is subjected to partial hydrodeoxygenation and (optionally) catalytic isomerization. The partial-hydrodeoxygenation of the triglyceride species produces a fuel that retains some oxygenates for enhanced lubricity. |
| US08523958B2 |
Fabrication of lithium secondary battery
A method of fabricating a lithium secondary battery, which improves charge-discharge characteristics, lifespan, and temperature characteristics of the battery and which includes interposing a separator between a positive electrode plate and a negative electrode plate, thus manufacturing an electrode assembly; housing the electrode assembly in a battery case, introducing an additive-containing electrolytic solution, and then sealing the battery case; subjecting the sealed battery case to pre-charging, and then removing gas generated by the pre-charging; subjecting the battery case to formation; and removing gas generated by the formation, wherein the additive is one or more selected from among LiF2BC2O4, 3,9-divinyl-2,4,8,10-tetraoxaspiro[5,5]undecane, LiB(C2O4)2, poly(ethyleneglycol)borate and derivatives thereof, halogen-substituted carbonate, and vinyl silane, and the pre-charging is conducted in a range of 10% or less of a battery capacity. |
| US08523956B2 |
Colouring composition for keratin fibres
Present invention relates to a coloring composition for keratin fibers especially for human hair with exceptionally improved color and shade stability. Accordingly, the first object of the present invention is a coloring composition for keratin fibres especially human hair comprising, in a cosmetically acceptable medium, at least one oxidative dyestuff precursor, 1,3-bis(2,4-diaminophenoxy) propane and/or its respective salts as a coupling agent and at least one direct dye. In an especially preferred from of the present invention the coloring compositions are substantially free from mono cyclic m-phenylenediamine coupling agent. With the term “mono cyclic m-phenylenediamine”, it is meant that the compound comprises only one cyclic group, preferably a benzene ring, in its molecule. |
| US08523950B2 |
Anatomical motion hinged prosthesis
A hinged knee prosthesis (10) comprises a tibial component (16) and a femoral component (14). The tibial component (16) is configured to attach to a tibia. The tibial component has a bearing surface (128). The femoral component (14) is configured to hingedly attach to the tibial component (16) and rotate relative to the tibial component (16). The femoral component (14) comprises a medial condyle (30) and a lateral condyle (32). The medial and lateral condyles (30 and 32) have an eccentric sagittal curvature surface (50) configured to rotate and translate on the bearing surface (128) of the tibial component (16). A method of rotating a hinged knee (10) through a range of flexion is provided. The method fixedly attaches a femoral component (14) to a tibial component (16). Axial rotation of the femoral component (14) is induced relative to the tibial component (16) when the hinged knee (10) is flexed. |
| US08523947B2 |
Interbody fusion system with intervertebral implant retention assembly
An implant assembly is disclosed, and includes an implant member and a plate configured to be coupled with the implant member. The plate defines a horizontal plane and includes at least one bore through the plate. The bore has an inlet aperture and at least one exit aperture. The inlet aperture has a curvilinear seat. A fastener is configured for insertion through the at least one bore, and the fastener has a curved portion. The curved portion of the fastener is configured to contact the contact the curvilinear seat to secure the plate to the implant member. |
| US08523946B1 |
Stand-alone spinal cage
A spinal cage device for fusion of spinal vertebrae comprising a cage body having a cavity defined by upper, lower, and side walls; a piston selectively insertable into the cavity through a side wall, the piston having at least one angled surface; at least one channel extending through at least one of the upper wall and the lower wall; at least one fastening member moveable within the at least one channel between a first disengaged position and a second engaged position; and wherein in second engaged position the at least one fastening member is held substantially stationary relative to the cage body by contact with the piston. According to one aspect of the invention, the device includes a locking means for supplementing fixation of the piston to the cage body. |
| US08523943B2 |
Method and device for the fixation of a tendon graft
A fixation device for securing a transplant in a bone tunnel, having a strap with a plurality of protrusions disposed along its length, a fastening member with an aperture therein for passing the strap, and a connection element disposed at a distal end of the strap for engaging a transplant is provided. The fixation device is configured such that, when the distal side of the fastening member lies substantially flush against an outer surface of the bone, a longitudinal axis of the aperture is substantially parallel to a longitudinal axis of the bone tunnel. A method for securing a transplant in a bone tunnel using the aforementioned fixation device is also provided. |
| US08523942B2 |
Variable focus intraocular lens
A variable focus intraocular lens comprises an optic coupled to at least one haptic at a flexion that sets a non-zero angle between the optic and the haptic. |
| US08523935B2 |
Tubular support prosthesis with laterally overlapping arcs of curvature
The present invention refers to a tubular support prostheses (stent) for vessels or intercorporeal lumina comprising at least two adjacently arranged expandable support rings connected to one another on at least one joint, said support rings being formed by a filament wound in a meander-like manner to form several arcs of curvature. The expansion behavior of such a support prosthesis is to be improved. For this purpose at least one arc of curvature of a first support ring and an arc of curvature of an adjacent second support ring overlap laterally, whereby the joint in the overlapping portion is formed. |
| US08523934B2 |
Fenestrated intraluminal stent system
An intraluminal prosthesis is provided for strengthening a main lumen and a branch lumen that branches from the main lumen. The intraluminal prosthesis can comprise two tubular grafts. The first tubular graft can have a flexible body with a fenestration. The second tubular graft can have a flexible body that is configured for intraluminal coupling to the fenestration of the first tubular graft. The flexible body of the second tubular graft can have an outer dimension that is about equal to an inner dimension of the fenestration of the first tubular graft. The second tubular graft can also have a terminal stent that curves outwardly from a proximal end of the flexible body of the second tubular graft, whereby the terminal stent acts to couple the second tubular graft to the first tubular graft. |
| US08523931B2 |
Dual concentric guidewire and methods of bifurcated graft deployment
A guidewire assembly for use in deploying a bifurcated endoluminal vascular prosthesis that has a main graft portion and at least a first branch graft portion The guidewire assembly include a hollow guidewire sheath having a restraint mechanism, such as a tubular sheath, for constraining a branch graft portion of the vascular prosthesis and an inner core wire that is slidably insertable into a central lumen of the hollow guidewire sheath. In use, the guidewire assembly may be used with a deployment catheter to deploy the bifurcated vascular prosthesis and leave the inner core wire in position in the patient's aorta, extending through the main graft portion of the vascular prosthesis. |
| US08523928B2 |
System for inner eyelid heat and pressure treatment for treating meibomian gland dysfunction
A system for treating meibomian gland dysfunction comprising a heating element that applies heat to the inside of the eyelid to provide conductive heat transfer to the meibomian glands, which assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. Temperatures at the meibomian glands reach desired higher temperature levels more quickly and efficiently when heating the inside of the eyelid, which may assist in removing obstructions in the meibomian glands. Less time may also be required to reach desired temperature levels when applying heat to the inside of the eyelid. A force application device may also apply force to the patient's eyelid to express the obstruction from the meibomian gland, including from a channel of the meibomian gland, and to increase the temperature level and/or reduce the time to reach desired temperature levels. |
| US08523926B2 |
Devices and methods for generation of subsurface microdisruptions for biomedical applications
A device comprises an energy source capable of generating short bursts of energy at a variable pulse repetition rates. The repetition rates range from a single shot to several hundreds Mega-Hertz so that selective, three dimensional interactions with a volumetric zone of skin or issue can be created substantially without damage or substantial changes to overlying or underlying or surrounding tissue or skin. |
| US08523925B2 |
Fiber optic phototherapy device
A phototherapy apparatus for the treatment of skin disease is disclosed including: an at least partially hollow body element; a plurality of light emitting elements enclosed within the body element; and a plurality of elongated light transmitting elements, each of the light transmitting elements having a proximal end detachably affixed to the body element in proximity to one or more of the light emitting elements, and extending to an end distal the body element. For each of the elongated light transmitting elements, at least a portion of light incident from the light emitting elements onto the proximal end is directed through the light transmitting element and emitted from the distal end. |
| US08523923B2 |
Clamping and articulation element
A two-piece clamping element comprises two separate, i.e., non-integral, opposing first and second clamping jaws forming a laterally open cavity to receive a pin or rod-shaped element. Each clamping jaw has a bore aligned with one another to receive a screw, wherein a pivot bearing is arranged opposite said cavity allowing the two opposing clamping jaws to come in contact to one another. The pivot bearing comprises at least one set of complementary part-cylindrical bearing surface portions. An anti-rotation pin extends between the two jaw members. |
| US08523921B2 |
Tibial plateau leveling osteotomy plate
An improved tibial plateau leveling osteotomy plate is disclosed. The plate is contoured in its proximal head portion to more closely resemble the structure of the tibial bone segment that is cut and rotated during the procedure. The plate also preferably has screw holes in the proximal head portion that are machined through the pre-contoured proximal head portion and are designed to angle the screw in a targeted screw path with respect to the osteotomy. |
| US08523919B2 |
Targeting guide with a radiopaque marker to facilitate positioning a bone plate on bone
Bone fixation system, including methods, apparatus, and kits, and comprising a bone plate and at least one instrument that attaches to the bone plate and provides at least one radiopaque region to facilitate positioning the bone plate on bone visualized by radiographic imaging. The instrument may be a handle assembly and/or a targeting guide. |
| US08523910B2 |
Lateral spinous process spacer
Interspinous process implants are disclosed. Also disclosed are systems and kits including such implants, methods of inserting such implants, and methods of alleviating pain or discomfort associated with the spinal column. |
| US08523909B2 |
Interspinous process implants having deployable engagement arms
Spinal implants include an elongated body portion dimensioned and configured for percutaneous introduction into a target interspinous process space, at which interspinous distraction and/or spinal fusion are desired. The body portion can include a threaded outer surface, or alternatively a smooth surface. The body portion can include one or more interior cavities, and can include deployable engagement members adapted and configured to move in tandem between a stowed position retracted within the interior cavity of the body portion and a deployed position extended from the interior cavity of the body for engaging adjacent spinous processes. An internal drive assembly for selectively moving the engagement members from the stowed position to the deployed position can be provided, as can a elements for locking the engagement members in a deployed position. |
| US08523906B2 |
Apparatus and devices for percutaneously extending an existing spinal construct
Apparatus and devices for percutaneously extending an existing spinal construct ipsilaterally with an additional spinal construct in a patient are disclosed. The additional spinal construct comprises a rod connector that includes an elongate additional rod integrally attached thereto. The additional rod is placed through an access port in a first orientation generally parallel to the longitudinal axis of the access port and rotated to a different second orientation generally transverse to the longitudinal axis of the access port. During such rotation the additional rod is moved subcutaneously beneath the skin of the patient from the existing spinal rod to an additional bone engaging implant. In another arrangement, the extension of an existing spinal construct in a minimally invasive procedure comprises a rod connector having an offset support for receiving an additional spinal rod that may be placed laterally interiorly or exteriorly of the existing spinal construct. |
| US08523901B2 |
Apparatus and methods for attaching soft tissue to bone
Suture anchors and methods for using the suture anchors for attaching soft tissue, such as ligaments, tendons, and muscles, to bone are disclosed. A suture anchor for attaching soft tissue to bone includes a catheter having an elongated shaft with a proximal end, a distal end, and a longitudinal axis between the proximal and distal ends, wherein the catheter has at least one inner lumen capable of allowing a light curable adhesive to pass through the inner lumen; a balloon portion engaging the distal end of the catheter, wherein the balloon portion expands from a deflated state to an inflated state when a light curable adhesive is delivered to the balloon portion; and at least one suture material for passing through soft tissue to attach the soft tissue to a bone. |
| US08523900B2 |
Medical manipulator
A medical manipulator includes a wire movable in opposite directions, a driven wire having both ends thereof connected to the wire, an end effector of a distal-end working unit, a transmitting member, a crescent driven member integral with the transmitting member, and a return pulley. The transmitting member, the crescent driven member, and the return pulley are successively arranged in this order from the proximal end of the medical manipulator. When the driven wire is moved in opposite directions, the transmitting member also moves in opposite directions. At this time, the crescent driven member moves toward the return pulley, and the proximal-end portion of the return pulley enters a cavity of the crescent driven member. |
| US08523896B2 |
Dynamic nasal molding method
A dynamic nasal molding device for presurgical molding of cleft lip deformities, the device having a pair of rotation assemblies each having an internal shaping member for insertion in a nostril and an external shaping member to be positioned external to the nostril, wherein the internal and external shaping members are progressively pivoted about the rotation assemblies, while simultaneously the separation distance between the rotation assemblies is decreased, to mold the nasal anatomy into the desired shape. |
| US08523895B2 |
Surgical obturator
An obturator has an elongated shaft with a first shaft portion and a second shaft portion within an obturator housing. The distal end of the first shaft portion creates a first shield and the distal end of the second shaft portion creates a second shield. A blade having a piercing tip and cutting edges is interposed between the first shield and the second shield. In use, once the piercing tip passes the body wall, the first shield moves to cover the piercing tip and protect internal organs from accidental injury while the cutting edges continue to cut the body wall. Once the second shield passes through the body wall, the second shield moves to cover the cutting edges. |
| US08523892B2 |
Instruments and methods for minimally invasive carpal tunnel release
Instruments for use in minimally invasive carpal tunnel release include a cannula and a cutting member movable longitudinally within the cannula to advance a cutting blade of the cutting member along a longitudinal slot in the cannula to sever a transverse carpal ligament disposed over the slot. A dilating member is provided for creating a subligamentous space to accommodate the cannula and/or for removing adhered synovium from a lower surface of the ligament. A method for minimally invasive carpal tunnel release involves establishing a proximal entry into the carpal tunnel from an incision in the volar aspect of the forearm, introducing the cannula in the carpal tunnel via the incision, and severing the transverse carpal ligament from proximal to distal with the cutting blade of the cuffing member under direct endoscopic visualization. |
| US08523891B2 |
Probe for carpal tunnel release tool or tissue dissection
A probe for a surgical instrument used for cutting selected tissue in a body cavity while under visual inspection, e.g., a surgical tool for the release of the transverse carpal tunnel ligament, has a profile where the flat top surface of the probe has a wider width dimension than the lower surface of the probe. Thus, the sides of the lower surface are sloped or curved inward such that all points below the flat top surface at any particular point on the first and second sides of the flat top surface have a width that is smaller than the width dimension of the flat top surface. The degree of sloping or curving inward will cause tissues to be moved downward (instead of upward) when the probe is inserted, and will provide for generating an upward force that firmly holds the probe against the tissue to be cut and a downward force on the surrounding tissue below the probe. |
| US08523889B2 |
Ultrasonic end effectors with increased active length
An end effector includes a first portion having a first specific acoustic impedance value, and a second portion having a second specific acoustic impedance value less than the first specific acoustic impedance value. The first portion includes a proximal end segment of the end effector and a distal end segment of the end effector, and the proximal end segment and the distal end segment are composed of a first material. The second portion includes an insert segment of the end effector composed of a second material. The insert segment is located between the proximal end segment and the distal end segment along the longitudinal axis of the end effector. The insert segment functions to bridge or fill the nodal energy gap. A surgical instrument includes a transducer configured to produce vibrations along a longitudinal axis as a predetermined frequency. An ultrasonic blade extends along the longitudinal axis coupled to the transducer. An insert segment or a pad is positioned adjacent to the blade such that it engages the blade when the surgical instrument is in a closed position and generates heat filling the nodal energy gap. |
| US08523888B2 |
Oral care implement
An oral care implement with a soft tissue cleanser is provided to effectively cleanse the soft tissue of the mouth with comfort and a reduced risk of injury to the user. In one construction, a projection is formed of a combination of a hard material and a soft material. The rigid material provides stability for cleaning debris from the tongue or other tissue while the soft material provides comfort and a reduced risk of injury. |
| US08523886B2 |
Device for fastening tissue layers
Endoscopic devices and methods used for fastening multiple tissue layers, such as, for example, an endoscopic fundoplication procedure, are disclosed. The endoluminal device includes a tissue fastener, a flexible needle having means for grasping and releasing a portion of the tissue fastener, and a deflector for deflecting and guiding the needle toward the multiple tissue layers. |
| US08523883B2 |
Apparatus and methods for treating tissue
Apparatus and methods are provided for thermally and/or mechanically treating tissue, such as valvular structures, to reconfigure or shrink the tissue in a controlled manner. Mechanical clips are implanted over the leaflets of a valve, e.g., in the heart, either alone or after thermal treatment to cause the valve to close more tightly. The clips are delivered by a catheter and may be configured to traverse directly over the valve itself or to lie partially over the periphery of the valve to prevent obstruction of the valve channel. The clips can be coated with drugs or a radiopaque coating. Alternatively, individual anchors with a tensioning element, like a suture, may be used to approximate the valves towards each other. The catheter can also incorporate sensors or energy delivery devices, e.g., transducers, on its distal end. |
| US08523881B2 |
Multiple anchor delivery tool
An anchor deployment tool includes a flexible outer tube, within which is positioned a flexible inner shaft, and a rotating deployment element coupled to a distal end of the shaft. The tool is configured to provide an anchor storage area, which initially stores a plurality of tissue anchors, such that the inner shaft passes through channels of the anchors along entire longitudinal lengths of the anchors, and the anchors are within the outer tube. The rotating deployment element is configured to directly engage the anchors in the anchor storage area one at a time, advance each of the anchors while engaged in a distal direction, and deploy each of the anchors through the distal tube end and into tissue of a subject. Other embodiments are also described. |
| US08523880B2 |
Medical clip and apparatus for the application of such a clip
In a medical clip consisting of a platelet of an elastic bio-compatible material, the platelet is provided with a central H-shaped cut-out so as to form a frame structure with tongues extending from the frame structure toward each other and having adjacent front edges forming grasping elements, and the frame structure is curved and elastically biases the front edges toward each other. |
| US08523879B1 |
Stone retriever for flexible endoscopes having small diameter working channels
A medical retrieval device and method used in endoscopic procedures to retrieve stones has a shaft comprising a sheath with a lumen and a drive wire slidably disposed within the lumen for operating a stone entrapping mechanism on the distal end of the retrieval device. The shaft has an average outside diameter of less than 1.9 Fr. The shaft, sheath and drive wire each have proximal, intermediate and distal portions, and each of the corresponding portions are in generally similar locations along the longitudinal length of the device. The proximal portions of the shaft and the drive wire are preferably stiffer than the corresponding intermediate portions of the shaft and drive wire. The proximal and intermediate portions of the sheath have generally similar stiffnesses. The shaft reduces flow resistance within the working channel of an endoscope, increasing the flow of irrigation fluid in order to improve procedural visibility. The shaft varies in flexibility to match the requirements of a flexible endoscope and facilitate deflection of the endoscope. |
| US08523878B2 |
Method of producing medical instrument
A method of producing a medical instrument whereby a highly hydrophilic and lubricant coating layer having a high durability can be formed by a simple technique and thus highly hydrophilic and lubricant properties can be imparted to a surface of a medical instrument. An intraocular lens insertion instrument having been subjected to a surface treatment as described above is also provided. The method includes preparing a coating solution by mixing at least a water-insoluble polymer having carboxyl group and a polyfunctional reactive compound with an organic solvent; applying this solution on the surface of the medical instrument; conducting crosslinking; and performing a chemical reaction process. The coating layer is made hydrophilic. The intraocular lens insertion instrument is made hydrophilic by forming the coating layer as described above on an inner surface of an insertion tube portion, crosslinking and then performing the chemical reaction process. |
| US08523877B2 |
Intraocular lens inserting instrument
An intraocular lens inserting instrument capable of folding a lens and pressing it by a plunger to discharge it into an eye and alternatively capable of taking out the folded lens by tweezers. The intraocular lens inserting instrument for inserting a foldable intraocular lens into an eye has a tubular body for allowing the intraocular lens to pass through it and introducing it into the eye, and a plunger for pressing the intraocular lens to discharge it into the eye, wherein the intraocular lens is folded by a folding member provided at a lens placing section. The lens placing section has an open/close lid so that the folded intraocular lens is accessible to be held by the tweezers. |
| US08523876B2 |
Systems and methods for compressing and distracting vertebrae of the spinal column
Spinal surgical systems include a compressor mountable to a first vertebra and positionable relative to a fulcrum mountable to a second vertebra. The compressor and fulcrum are manipulated relative to one another to compress the first and second vertebrae. The systems further include a distractor mountable to a first vertebra and positionable relative to a fulcrum mountable to a second vertebra. The distractor and fulcrum are manipulated relative to one another to distract the first and second vertebrae. |
| US08523873B2 |
Neural-monitoring enabled sleeves for surgical instruments
A neural monitoring enabled insulating sleeve for use with a surgical instrument during a surgical procedure on a patient in patient body tissue includes a tubular portion having a proximal end, a distal end, and a bore extending therethrough. The bore is configured to receive the surgical instrument. The tubular portion being formed of a material that electrically insulates the surgical instrument from the patient body tissue and having a flexible portion configured to flex between a locked and an unlocked condition. A camming component is configured to interface at the proximal end of the tubular portion. It is configured to cam the flexible portion between the locked and unlocked condition. |
| US08523872B2 |
Tibial resurfacing system
A tibial resurfacing system is provided that includes a drill guide, bone chisel and implant. In one aspect, the system includes a drill guide that includes a targeting ring that is shaped to be placed on the superior tibial surface and a bore section that is connected to the ring to create an axis through the tibia to the superior tibial surface in the vicinity of the targeting ring. The drill guide permits a drill pin and/or drill to be advanced through the tibia to the superior tibial surface. In another aspect, a bone chisel is provided that includes an elongated tubular structure having a first end and a bone-cutting end, and the bone-cutting end is terminated in a transverse angle thereby creating an elliptical bone-cutting face. In another aspect, an implant is provided that includes an angled bearing element formed of a cylindrical member having a first end and a second end. The first end is formed at an angle that creates an elliptical face of the first end, and the first end defines a load-bearing surface of an articular surface. |
| US08523871B2 |
Bone treatment systems and methods
Systems and methods for delivering bone cement into a bone can include a handle body defining a flow path, a thermal emitter in the handle body to apply energy to bone cement passing through the flow path, a source of bone cement and an injection cannula. The cannula can be in communication with the flow path such that inserting the cannula into a bone can allow a flow of bone cement therethrough to an opening at a distal end of the cannula. Other systems and methods for delivering bone cement into a bone can include an injector body with a handle portion, and a cannula, a bone cement container, a low pressure drive mechanism configured to effect a flow of bone cement from said container to the injector body and a high pressure drive mechanism configured to effect a flow of bone cement through the injector body into the bone. |
| US08523870B2 |
Adjustable femoral resection guide
A chamfer resection guide assembly for effecting chamfer cuts into a resected distal surface of a femur in connection with a distal total knee implant has an anchor member configured for anterior referencing of the chamfer cuts, a block member including one or more cutting guide slots for guiding a cutting tool for making chamfer resections and a camming member. The camming member operably connects the block member and the anchor member and the position of the block member with respect to the anchor member is adjusted by operation of the camming member thus allowing adjustment of the position of the cutting guide slots with respect to the anchoring member. |
| US08523868B2 |
Surgical cutting instrument with dual surface interlocking coupling arrangement
A hand-held surgical cutting instrument for cutting bone material with a surgical micro-saw blade has a plurality of openings formed therein. The surgical cutting instrument includes a hand-graspable body for manipulating the cutting instrument and a blade coupling mechanism attached to the body and being configured to attach to the surgical micro-saw blade. The blade coupling mechanism includes a first coupling member including a first blade-contacting surface. The first blade-contacting surface has at least one first protrusion extending therefrom and is configured to engage a first opening in the surgical saw blade. The blade coupling mechanism includes a second coupling member including a second blade-contacting surface facing the first blade-contacting surface of the first coupling member. The second blade-contacting surface having at least one second protrusion extending therefrom and configured to engage a second opening in the surgical saw blade. |
| US08523864B2 |
Instrumentation for the preparation and transplantation of osteochondral allografts
Provided are procedures and instruments for preparing and transplanting osteochondral allograft plugs to a host bone to repair an articular cartilage defect. An allograft bone plug having a cartilage plate and cancellous bone tissue attached thereto is removed from a donor bone. The allograft plug is further shaped by removing or cutting away cancellous bone tissue to form a cancellous stalk extending from the cartilage plate. The formed cancellous stalk can have any suitable shape including cylindrical, conical, and rectilinear. At the recipient site of the host bone, a cutout is formed corresponding in shape to the allograft plug. The allograft plug is inserted into the cutout such that the cancellous stalk is retained in the host bone and the cartilage plate aligns with the condyle surface of the host bone. Aspects of the invention may also be applicable to preparing and transplanting osteochondral autograft plugs. |
| US08523863B2 |
Self-retaining cable tie
A system for securing a bone fixation device to a bone comprises a flexible longitudinal element configured to wrap about and stabilize one of a target portion of bone and a bone stabilizing element. The longitudinal element includes a plurality of projections extending distally from a first surface thereof. Each projection includes a proximal abutting surface in combination with a bone fixation element including a channel extending therethrough sized and shaped to slidably receive therein a portion of the longitudinal element distal of the head. The bone fixation element includes a recess shaped to receive the head and prevent the head from being drawn distally through the channel. The bone fixation element or the longitudinal element includes a tab configured to engage one of the proximal abutting surfaces to prevent the projections of the longitudinal element from moving proximally relative to the tab. |
| US08523858B2 |
Adjustable fixation clamp and method
An adjustable fixation clamp having first and second clamp assemblies positioned about a shaft. The clamp assemblies may each have a pair of vise plates. Each pair of vise plates may define at least two receiving portions and insertion portions intersecting the receiving portions. The receiving portions of one clamp assembly may receive at least two fixation components such as screws, pins or wires. The receiving portions of the other clamp assembly may receive at least one connector such as a rod, bar and/or ring. A biasing structure may be positioned between the first and second clamp assemblies and may allow for the fixation components to be snapped into the receiving portions through the insertion portions. Two or more adjustable fixation clamps may be used to form an external fixation system. At least two screws, pins or wires may be inserted into bone and one of the clamp assemblies may be attached thereto. A guide may be used for insertion of screws, pins or wires into bone. The other clamp assembly may be connected to a rod, bar or ring. Thereafter, the clamp assemblies may be oriented relative to each other and locked in place. |
| US08523851B2 |
Inductively heated multi-mode ultrasonic surgical tool
Thermal, electrosurgical and mechanical modalities may be combined in a surgical tool. Potentially damaging effects in a first modality may be minimized by using a secondary modality. In one example, thermal hemostasis may thus help electrosurgical applications avoid the adverse tissue effects associated with hemostatic monopolar electrosurgical waveforms while retaining the benefits of using monopolar incising waveforms. |
| US08523849B2 |
Radiation-based dermatological devices and methods
A self-contained, hand-held device for providing a dermatological treatment includes a device body configured to be handheld by a user; a radiation source supported in the device body, the radiation source including a beam source configured to generate an energy beam; an application end configured to be manually moved across the surface of the skin during a treatment session; electronics configured to pulse the radiation source during the treatment session such that the beam source emits pulsed energy beams to the skin; and a displacement control system including a displacement sensor configured to determine a displacement of the device relative to the skin, and electronics configured to control at least one operational parameter of the device based on the determined displacement of the device relative to the skin. |
| US08523848B2 |
Non-invasive laser vasectomy
The present invention presents novel methods for performing noninvasive vasectomies in animals, including humans, and vasectomy clamps for use in such procedures. The invention further presents an apparatus for use in noninvasive male sterilization procedures. More specifically, the invention presents the application of lasers for noninvasive thermal coagulation and occlusion of the vas. Non-contact cooling of the tissue surface, for example, via cryogen or other cooling spray, prevents scrotal skin burns during the procedure. Both the laser radiation and cooling spray are delivered in a non-contact mode to the tissue. This procedure also preserves the surgical field-of-view, potentially allowing the urologist to visually monitor the skin surface during subsurface heating of the vas and preventing the formation of scrotal skin burns. |
| US08523844B2 |
Surgical instrument with tendon preload-and-locking device
A surgical instrument includes a handle, an elongated shaft and an end effector extending distally from the shaft. A tensile member is preloaded with a tensile force and extends at least partially through the shaft. A preload mechanism for adjusting the tensile force includes first and second guides in contact with the tensile member to restrain the tensile member at respective first and second lateral distances from a longitudinal axis. A third guide is disposed longitudinally between the first and second guides and is in contact with the tensile member to restrain the tensile member at a third lateral distance from the longitudinal axis. The third guide is movable to vary the third lateral distance and a corresponding length of the tensile member disposed longitudinally between the first and second guides to thereby vary the tensile force. |
| US08523840B2 |
Connector system for a proximally trimmable catheter
A catheter connector system for a subcutaneously placed catheter and method of attaching a catheter to extracorporeal medical equipment. The catheter connector system and method enables proximal trimming of the placed catheter and facilitates precise positioning of both distal and proximal ends of a catheter. The method includes sliding a boot and dilator combination over a portion of a catheter extending from a venipuncture site until a distal end of the boot is positioned in the venipuncture site, removing the dilator from the boot, and trimming a portion of the catheter extending from a proximal end of the boot. A bifurcation assembly may be attached to the proximal end of the boot following trimming of the catheter. |
| US08523837B2 |
Nutritive substance delivery container
The invention comprises a novel apparatus for delivering a nutritive substance comprising a container body having a base at one end, an upper portion adapted for removable receipt of a closure, the upper portion defining an opening therein, and a chamber defined by the container body, the chamber being in fluid communication with the opening. A laminate seal having at least two layers is bonded across the opening and is adapted to provide an airtight seal across the opening and prevent contact between said nutritive substance and the contents of said container until said seal is altered. The laminate seal comprises a first layer permanently bonded to a rim defining the opening in the upper portion and a second layer that is releasably coupled to the first layer. A nutritive substance is bonded to the first layer. The container additionally comprises a closure removably coupled to the upper portion. |
| US08523835B2 |
Pant-type disposable absorbent hygiene product
A pant-type disposable absorbent hygiene article (2), comprises a waist edge (20), continuous in the circumferential direction thereof and forming a waist opening, and leg openings (8a,b), a front piece (6) and a back piece (4) having longitudinal side edge sections (16,18), and a crotch region (10), disposed between the front piece (6) and the back piece (4). The waist edge (20), continuous in the circumferential direction thereof, and the leg openings (8a,b) are produced by joining, on the manufacture end, the longitudinal side edge sections (16,18) of a front piece (6) and a back piece (4). The hygiene article also comprises an absorbent body (22). Every leg opening (8a,b) has an elastic leg opening section (81). Cuff elements (7) are provided on both sides of the absorbent body (22) and extend in the longitudinal direction (28) thereof, each cuff element (7) having an elastic cuff element section (9), and a) every cuff element (7) having at least one non-elastic cuff element section (11) and, when the product is placed on the body of the user, the elastic leg opening section (81) crosses the respective non-elastic cuff element section (11) or b) the length of the respective cuff element (7) being chosen in such a manner that, when the product is placed on the body of the user, the elastic leg opening section (81) does not cross the respective cuff element (7). |
| US08523834B2 |
Variable stretch composites and methods of making the composite
Process for making a variable stretch composite comprising the steps of providing a first extensible fibrous substrate, printing a first elastomeric composition to a first elasticized region of the substrate, printing a second elastomeric composition to a second elasticized region of the substrate, and incrementally stretching at least a portion of the composite perform to form a variable stretch composite. |
| US08523833B2 |
Sanitary napkin
The sanitary napkin includes an inner core of absorbent material that is spirally or helically wound along its length and tapers in diameter from a larger first end to a smaller second end. A layer of soft, pliable, liquid-pervious material encapsulates the inner core. The larger end of the napkin is configured in a thin flat profile and is provided a string or other positioning member to enhance placement and removal of the napkin. Although described above as an absorbent pad for vaginal discharge, it is recognized that the napkin could also be used to absorb rectal discharge in instances after hemorrhoid surgery and the like. |
| US08523825B2 |
Dispenser device
A dispenser device comprising a pistol housing, a needle direction control mechanism, a boost mechanism, a quantification control mechanism, and a combination of the pistol housing, the needle direction control mechanism, the boost mechanism, and a syringe positioning mechanism or a holding ring embodies the present invention with features and advantages shown as follows, (1) Uniform injection of agents synchronously mixed by not less than two contents; (2) Mixed agents not exposed in air; (3) Uniform injection, high air tightness, injection direction controlled by easy turning, smooth and convenient operation, high powerful operation via shifts of a push rod driven by a pressed trigger, promoted yield rate, assembly easily constructed, reduced manufacture cost, and convenient maintenance. |
| US08523822B2 |
Tearaway sheath assembly with split hemostasis valve seal
A tearaway sheath assembly (100) having a splittable sheath tube (102) a splittable hub (110), a split valve (150,250) and a split cap (180). The valve (150,250) has a slit (158,258) at least partially across the transverse distal section (154) such that transverse distal section may be displaced laterally during insertion through the slit (158,258), of a dilator (200) or a catheter. The valve (150,250) is formed in two separate halves (152A,152B;252) that are fused or adhered to each other to form a sealed weak bond (154) that is easily broken during splitting of the sheath; each valve half is mechanically affixed in a proximal valve-receiving recess (130) of the hub such as by anchor posts (136) extending through apertures (166A,166B) in ears (164A,164B) of each valve half. A two-part cap (180) is affixed to the hub proximal end (120) and traps the valve between itself and the hub. Pairs of opposed gaps (184,122) of the cap (180) and the hub (110) are aligned with lines of weakness or seams (106) of the sheath tube (102) and the weak bond (154) of the valve, facilitating splitting of the assembly (100) when desired by the practitioner to peel it away from the inserted catheter. |
| US08523821B2 |
Power injection valve
A device for transferring fluids between an internal structure in a living body and an exterior thereof comprises a housing including a pressure activated lumen extending to a distal end opening to a power injection lumen that extends to a distal port configured for connection to a fluid conduit extending to a target structure within the body and a pressure activated valve extending across the pressure activated lumen and controlling fluid flow therethrough, in combination with a proximal port coupled to the housing for movement between a first position in which a proximal end of the power injection lumen opens to the proximal port and a second position in which a proximal end of the pressure activated lumen opens to the proximal port. |
| US08523817B2 |
Veress needle with illuminated guidance and suturing capability
A laparoscopic instrument for forming an incision in a body cavity, insufflating the body cavity with gas, and suturing the incision at the completion of the surgery includes a set of jaws at the distal end of the Veress needle or cannula. The jaws are pivoted to one another for motion between an open position or a closed position in which they may be used to grasp a suture in the body cavity for removal from the cavity for knotting. A push mechanism at the proximal end of the instrument moves the jaws between their open and closed position on successive actuations of a pushbutton and retains them in that state until the next push. An illumination source is provided for the distal end of the instrument to provide illumination through the walls of the body cavity so that the surgeon can determine the degree of penetration of the instrument into the body cavity and can identify any major arteries which should be avoided in the formation of other laparoscopic openings. |
| US08523809B2 |
Device for shielding a sharp tip of a cannula and method of using the same
A safety device for shielding a sharp tip of a tubular needle includes a shaft sized and shaped for being received into the passage of the tubular needle through a first end of the passage and extending to a second end of the passage. A shield is associated with the shaft and is constructed for receiving and substantially shielding the sharp tip of the needle. A catch is associated with the shaft. The catch prevents the withdrawal of the shaft from the passage of the needle when the shield is shielding the sharp tip of the needle. |
| US08523804B2 |
Breast attachment
The invention relates to a breast attachment, in particular a flexible insert for a breast pump or a nipple shield, wherein the insert or shield applies a positive massaging effect on a breast mimicking the natural stimulation of a baby breast feeding. |
| US08523803B1 |
Motor health monitoring and medical device incorporating same
Apparatus are provided for motor control systems and related medical devices. In one embodiment, a control system includes a motor having a rotor, a modulation module coupled to the motor, and a control module coupled to the motor and the modulation module. The modulation module generates a modulated voltage that is applied to the motor, and the control module adjusts a duty cycle of the modulated voltage to achieve a commanded rotation of the rotor and detects a degradation condition based on the duty cycle. |
| US08523801B2 |
Catheter with associated extension lumen
An intra-luminal device for the extraction of occlusive or partially occlusive material is disclosed. Said device comprises a novel catheter extension which minimizes cavitation of extracted fluids and also allows the better navigation of tortuous lumens or vasculature. |
| US08523798B2 |
Method for measuring recirculation in catheters
A system and method for measuring recirculation of blood in a catheter designed for implantation in a human is described. In one variation, the system comprises an artificial circulatory system and an ultrasonic detection device for measuring and comparing the density of a circulated blood simulant with a later introduced bolus saline. The system may be configured to simulate a human heart by providing the flow, pressure and dimensions of a typical human heart. In addition to simulating the circulatory system of a normal human heart, the system may also be configured to simulate particular negative conditions of a patient, such as stenotic condition, which would affect the recirculation measurement. |
| US08523795B2 |
Arm sling with backpack straps
A sling with straps configured in a manner similar to those of a backpack. The sling includes a waist strap connected at one end to an anterior portion of the sling pouch and at a second end to a posterior second portion of the sling pouch. The sling include first and second straps that are worn over respective shoulders of the body. One of the straps is connected at one end a first end of the pouch and at an opposite end to a second (opposite) end of the pouch. The second strap is connected at one end to the first end of the pouch and at an opposite end to the waist strap. The sling can also include an abduction pillow. |
| US08523793B1 |
Therapeutic joint cover apparatus
A therapeutic joint cover apparatus for massaging a knee while also providing compression that includes a tapered support body having an oval cutout centrally disposed therein which is surrounded by vibrating motors. A trio of length adjustable straps engages respective rings on the opposite side of the support body and a hook portion of hook and loop fastener disposed the straps' outer ends removably attach to an outer side of the support body to secure the support body to a user's knee. An interior lining disposed on the support body inner side provides a cool comfortable fit between the vibrating nodes and the user's knee. The apparatus is self-contained, including an on-off pressure-switched rechargeable battery housed in a pocket proximal to the top end so that no assembly or other preparations are required. |
| US08523790B2 |
Walking assistance device
A walking assistance device has a drive mechanism for driving a third joint of a leg link of the walking assistance device, the drive mechanism including a crank arm secured to a lower link member and a linear-motion actuator which has a linear-motion output shaft connected to the crank arm. The angle formed by a straight line connecting a joint axis of the third joint and a connecting portion of the linear-motion output shaft relative to the crank arm and a straight line which passes the connecting portion and which is parallel to the axial center of the linear-motion output shaft changes from an angle closer to the straight angle toward an angle closer to the right angle as the flexion degree of the leg link is increased from a flexion degree corresponding to a state wherein a user is in an upright posture. |
| US08523786B2 |
Controllable stiffness catheter guide device
The invention relates to a guide device (1), in particular for positioning catheters in a body duct. The guide device (1) has an extended first thread (2) and at least one extended second thread (3) made from wire, which runs close to the first thread (2). According to the invention, the guide device (1) has a device (8), provided for one of the threads (2, 3) by means of which it is possible to actively control a relative movement between the threads (2, 3) or at least make the same difficult. The control device (8) is for example embodied such that the first thread (2), prepared from a flexible material, exerts a pressure, preferably acting a radial direction, on the several second threads, or that magnetic fields (4) of differing polarities along the first thread (2), prepared from a flexible material and along the second thread (3), may be generated for the selective introduction of an opposing attraction of the threads (2, 3) for reinforcing the guide device (1). |
| US08523781B2 |
Bidirectional physiological information display
A patient monitor for displaying a physiological signal can include a visual element having a middle portion indicative of a transition in the physiological signal between physiological states. The visual element can also include first and second extremity portions, the first extremity portion extending from the middle portion in a first direction and the second extremity portion extending from the middle portion in a second direction. The visual element can also include an actionable value indicator to specify a value about the middle portion and the first and second extremity portions. The patient monitor can also include a processor configured to cause the value indicator to actuate in both the first and second directions according to changes in the physiological signal. |
| US08523777B2 |
Method, apparatus and system for predicting electromechanical dissociation
A method of predicting onset of electromechanical dissociation in a heart of a subject is disclosed. The method comprises: extracting from the composite input signal an electrocardiac signal and determining electrical activity of the heart based on the electrocardiac signal; extracting from the composite input signal a radiofrequency signal and determining blood flow measure based on the radiofrequency signal; and if the blood flow measure is below a predetermined threshold and the electrical activity is above a predetermined threshold, then predicting the onset of electromechanical dissociation. |
| US08523771B2 |
Cardiovascular pressure annotations and logbook
A system comprises an external medical device configured to communicate with a first implantable medical device (IMD). The external medical device includes a communication circuit and a display. The communication circuit is configured to receive information associated with cardiovascular pressure from the IMD. The external medical device is configured to annotate a waveform on the display to indicate one or more events associated with cardiovascular pressure. |
| US08523770B2 |
Surgical retractor and related methods
A surgical retractor includes a base defining an open area therein to correspond with a surgical incision in a body. The base has an inner wall facing the open area and an outer wall facing away from the open area. A plurality of channels extend through the base between the inner and outer walls, and at least one of the channels is at an angle offset from normal to the inner wall where the at least one channel intersects the inner wall. A respective retractor arm is carried within each of the channels for retracting the body to open the surgical incision. In a surgical method, such as a thyroidectomy, a base is positioned so that the open area corresponds with a surgical incision in a body. Respective retractor arms carried within each of the channels are moved to retract the body to open the surgical incision. |
| US08523768B2 |
Surgical access system and related methods
A surgical access system including a tissue distraction assembly and a tissue refraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site. |
| US08523767B2 |
Add-on retractor element for retractor system
A retractor assembly for percutaneous surgery in a patient that includes first and second retractor portions positionable opposite one another in an incision of the patient. A working channel extends between the first and second retractor portions and provides access to a location within the patient adjacent to distal ends of the first and second retractor portions. The first and second retractor portions are movable relative to one another to adjust the size of the working channel. An add-on retractor element is provided that is mounted to the first and second retractor portions and spans the gap between the first and second retractor portions to prevent creep of soft tissue into the working channel when the retractor portions are separated. |
| US08523766B2 |
Endoscope
The endoscope is equipped with: a curving manipulation unit provided on the main body manipulating unit, for performing a manual operation which causes the curving portion; a curving drive unit for coupling the curving manipulation unit to the curving portion so as to curve the curving portion in response to a manipulation performed by the curving manipulation unit; a manipulating force detecting unit for detecting a manipulating force applied to the curving manipulation unit; a manipulation assisting power calculating unit for calculating manipulation assisting power corresponding to the manipulating force detected by the manipulating force detecting unit; and a rotation driving force generating unit for applying a driving force via a driving force transferring mechanism to the curving drive unit, so as to generate the manipulation assisting power calculated by the manipulation assisting power calculating unit; in which the rotation driving force generating unit is arranged in an appendix unit. |
| US08523765B2 |
Medical control apparatus
A controller includes a servo controller that performs attitude control of the bending portion. A point lock computing section is provided at the servo controller. Based on supplied distal end command value information and position feedback information, the point lock computing section performs computational processing by a distal end link root coordinate position calculating section and an inverse kinematics computing section in order to obtain a servo position command signal for a distal end-side link member and a servo position command signal for a link member other than the link member, and outputs the same to a driving section. Accordingly, point lock is enabled at two locations, namely, the distal end-side link member and an arbitrary link member, while other link members are controlled so as to assume attitudes having redundancy. |
| US08523764B2 |
Remote viewing apparatus
A remote viewing device including a hand-holdable control unit. The control unit supports a display device and a drive assembly. The drive assembly is removably attached to the control unit and provides mechanical power to an insertion tube. A distal end of the insertion tube includes an inspection head for insertion into a structure for imaging the interior of the structure. The insertion tube is removably attached to the drive assembly by a connector assembly, where the connector assembly is operable, when attached, to convey mechanical power from the drive assembly for moving the articulated tip in response to a user input at the control unit, and to convey images from the inspection head to the display device. |
| US08523763B2 |
Lumen probe apparatuses and methods for using the same
A probe apparatus adapted for movement through a lumen, comprising: a linearly extendible and retractable element adapted for selective extension and retraction to provide the movement; a front balloon positioned forward of the linearly extendible and retractable element and adapted for selective inflation and deflation; a rear balloon positioned backward of the linearly extendible and retractable element and adapted for selective inflation and deflation; and, a twisting element adapted to twist at least one of the linearly extendible and retractable element, front balloon and rear balloon during inflation and deflation of the advancement balloon. |
| US08523759B2 |
Methods and devices for cardiac surgery
Methods for performing minimally invasive heart surgery include accessing a heart of a patient through a first incision on the left thorax of the patient, contacting the heart through the incision with a heart stabilizing device and/or a heart positioning device, introducing at least one coupling device through a second incision on the patient located apart from the first incision, coupling the coupling device with the heart stabilizing device or the heart positioning device, and performing a surgical procedure on the heart. Systems may include a retractor device, a heart stabilizing device, and a coupling device, for enhancing cardiac surgery. Any suitable heart surgery may be performed using methods, devices or systems of the present invention. In one embodiment, a CABG procedure is performed. |
| US08523758B1 |
System and method of treatment for insomnia and occasional sleeplessness
A system configured to provide breathing cues to a patient to alleviate insomnia or sleeplessness. In one embodiment, the system comprises a pressure support apparatus, a patient monitor, and a processor. The pressure support apparatus is configured to provide a pressurized flow of gas for delivery to an airway of the patient. The patient monitor configured to generate one or more signals that convey information related to one or more physiological functions of the patient. The processor in operative communication with each of the pressure support apparatus and the patient monitor. The processor is configured (i) to determine whether the patient is asleep or awake based at least in part on the one or more signals generated by the patient monitor, and (ii) to control the pressure support apparatus such that if the patient is determined to be awake, one or more properties of the flow of gas are varied according to a first predetermined algorithm designed to provide breathing cues to the patient that prompt the patient to breathe at a target breathing rate. |
| US08523757B2 |
Arterial device, system and method for removing embolic debris
An arterial device, system and method are provided for use with a patient undergoing a cardiac procedure. The system is configured for enabling one or more arterial devices to be accommodated in the aorta of the patient in use of the system, and a perfusion lumen arrangement provides therethrough a target perfusion flow into the aorta having a target perfusion flow rate that is significantly greater than a nominal perfusion flow rate, by an excess perfusion flow rate. A suction lumen arrangement provides therethrough a suction flow out of the aorta at a suction flow rate. The target perfusion flow rate and the suction flow rate may be concurrently and selectively controlled to cause embolic debris that may be present in the aorta to be diverted to the suction inlet, while providing the nominal flow rate to the body circulation of the patient. |
| US08523753B2 |
Transcranial magnet stimulation of deep brain targets
The treatment of specific neurological and psychiatric illnesses using Transcranial Magnetic Stimulation (TMS) requires that specific neuroanatomical structures are targeted using specific pulse parameters. Described herein are methods of positioning and powering TMS electromagnets to selectively stimulate a deep brain target region while minimizing the impact on non-target regions between the TMS electromagnet and the target. Use of these configurations may involve a combination of physical, spatial and/or temporal summation. Specific approaches to achieving temporal summation are detailed. |
| US08523751B2 |
Endless screw of a centrifuge with ceramic wear plates
The invention relates to an endless screw of a centrifuge for discharging centrifuged material from a centrifuge, comprising a series of thin ceramic plates which are fixed next to one another at the outer edge of the screw, characterized in that at least two formed ceramic projections, particularly ceramic pins, protrude from the thin ceramic plates and are arranged in one or two lateral faces of the edge of the screw, i.e. in recesses which are profiled according to the protrusions or pins. |
| US08523746B2 |
Machine tool with a chain magazine
A machine tool with a chain magazine has a chain guide which extends in the x, y, and z-directions. It also has a magazine chain, which has chain members, which are connected to one another by means of universal joints and in each case have a tool receiver. The magazine chain is guided by means of the chain guide. The chain magazine is moveable in the z-direction for tool changing operations. |
| US08523744B2 |
Progressive resistance exercise device
A device is provided that includes a post, an arm assembly being pivotably connected to the post at one or more connection points, a set of beams comprising an upper beam set and a lower beam set, wherein the upper beam set and the lower beam set each comprise one or more beams, the set of beams being pivotably connected to the post, wherein the post is connected to the upper beam set and the lower beam set such that the lower beam set and the upper beam set are positioned at a first distance apart from one another at their connection point with the post, a platform being pivotably connected to the set of beams, wherein the platform is connected to the upper beam set and the lower beam set such that the lower beam set and the upper beam set are positioned at a second distance apart from one another at their connection point with the platform and a lift tube having a length and being pivotably connected to the upper beam set at one or more connection points and the arm assembly at one or more connection points. |
| US08523742B2 |
Baby walker
A baby walker is introduced herein. The baby walker includes a base and a pair of shoulder straps. The base is made by flexible materials such as plastics, or the similar materials. In one exemplary embodiment, the base of the baby walker may be packaged in a deflated form, and may be filled with air to form a shape as desired for an operation mode. The baby walker further includes a pair of shoulder straps which are firmly and fixedly attached in a peripheral upper side of the base. When the baby is placed in a central cavity of the base, the pair of the shoulder straps can be placed alongside the two shoulders of the baby. When the baby wears the baby walker and stands up, the whole baby walker is lifted up for a height above the ground level. |
| US08523741B2 |
Method and system for monitoring sport related fitness by estimating muscle power and joint force of limbs
The present invention relates to a method and system for monitoring sport related fitness by estimating muscle power and joint force of limbs, in which the system comprises a sensing module and a force/track detection module, wherein sensor values from the sensing module are fed to the force/track detection module to be used as base for estimating feature parameters and classifying a motion series relating to muscle power and joint force of limbs so as to obtain skill-related fitness parameters corresponding to the sensing of the sensor module. |
| US08523738B2 |
Method of shifting a tandem drive axle having an inter-axle differential
A method of shifting a power distribution unit for a vehicle from a first operating state to a second operating state is provided. The method includes the step of adjusting a rotational speed of a portion of a second axle assembly using a clutching device to impart energy to a lubricant within the second axle assembly. A controller in communication with a power source of the vehicle adjusts an operating condition of the power source to facilitate moving the clutching device. The power distribution unit includes an inter-axle differential capable being placed in a locked condition by the clutching device and of accommodating a rotational difference between a first output gear and a second output gear with the inter-axle differential. |
| US08523736B2 |
Control apparatus for vehicular power transmitting system
A control apparatus for a vehicular power transmitting system includes a shifting-point changing portion configured to change a shifting point at which a determination to perform a shifting action of a transmission portion is made, such that a shifting portion is changed according to a shifting response of the transmission portion. Alternatively, the control apparatus includes a shift-control start-point changing portion configured to change a shift-control start point at which the determination to perform the shifting action is made, such that the shift-control start point is changed according to the shifting response of the transmission portion, and a compulsory shift-control starting portion configured to make the determination when an operating point of a differential portion electric motor has reached the shift-control start point. |
| US08523733B1 |
Vehicle driveline differential with improved efficiency during vehicle cold starts
The present disclosure relates to a vehicle driveline differential with improved efficiency during vehicle cold starts, the differential includes: a pinion; and a pinion bearing journaled onto a shaft of the pinion. The pinion bearing includes a thermal-insulation sleeve. |
| US08523731B2 |
Welded component, in particular planet wheel carrier, method for producing the component and apparatus for carrying out the method
A welded component comprising two sheet metal components (51, 53) joined by at least one weld seam (55). A first sheet metal component (51) is disk-shaped and a second sheet metal component (53) is pot-shaped, and at least one of the two sheet metal components (51, 53) has a sheet thickness (s). One (51) of the two sheet metal components (51, 53) has a larger sheet thickness (S>s) in an area of the at least one weld seam (55). |
| US08523729B2 |
Multi-speed transmission
A transmission includes an input and output member, two planetary gear set assemblies each having first, second, third, and fourth members, one interconnecting members continuously interconnecting a member of the first planetary gear set assembly with a member of the second planetary gear set assembly and six torque transmitting mechanisms selectively engageable to interconnect one of the first members, second members, third members, and fourth members with at least one of the input member and a stationary member. The torque transmitting mechanisms are selectively engageable in combinations of at least three to establish at least nine forward speed ratios and at least one reverse speed ratio between the input member and the output member. |
| US08523727B2 |
Multi ratio drive
A multi ratio drive including a first drive chain having a first drive chain engaged state and a first drive chain disengaged state; and a second drive chain having a second drive chain engaged state and a second drive chain disengaged state. The first drive chain drives the axle with a first gear ratio between the drive shaft and the axle when the first drive chain is in the first drive chain engaged state and the second drive chain is in the second drive chain disengaged state; the second drive chain drives the axle with a second gear ratio between the drive shaft and the axle when the second drive chain is in the second drive chain engaged state and the first drive chain is in the first drive chain disengaged state; and the first gear ratio is different from the second gear ratio. |
| US08523726B2 |
Hybrid drive for a motor vehicle
A hybrid drive for a motor vehicle which has a combustion engine, a transmission with a transmission input shaft which can be coupled with the combustion engine, and an electric machine which is positioned between the combustion engine and the transmission. The electric machine has a stator and a rotor which interacts with the transmission input shaft and is supported by a transmission housing input part. The transmission input shaft is supported, by a fixed radial bearing and a spaced radial bearing, in a bearing journal of the transmission housing input part. The rotor is connected, in a rotationally fixed manner, to an extension of the transmission input shaft which protrudes from a bearing journal. A radial shaft seal is positioned at the end of the bearing journal, facing the rotor, and the two radial bearings are cooled and lubricated by transmission oil. |
| US08523721B2 |
Belt tensioner
A tensioner system for tensioning a power transfer member such as a chain or a belt is disclosed. In one example, the system includes a base adapted to rotate about a main shaft that is operatively coupled to a motor, a housing positioned around the main shaft and a plurality of deformable elastic members positioned within the housing. The system further includes a plurality of deforming members positioned within the housing around the main shaft, wherein the plurality of deforming members are adapted to be urged in a radially outward direction so as to deform the deformable elastic members. |
| US08523720B2 |
Chain tensioner
A chain tensioner for use on a chain drive system is disclosed which has a housing open at both ends. Into the housing, a cartridge is inserted, the cartridge having including a body with a cylinder within and a piston. A retention system is provided to substantially prevent the body of the cartridge from moving with respect to the housing. Such a retention system, in one embodiment, includes a lip at a first end of the body and a groove on a second end of the body. The lip serves as a stop to prevent the body of the cartridge from moving axially beyond the stop in one direction. A clip is interlocked into the groove on the second end of the body of the cartridge to prevent movement in the opposite direction. |
| US08523715B2 |
Basketball backboard and rim mounting system
Certain embodiments of the present system deal with a basketball goal assembly which adjustably supports a backboard assembly and a rim assembly to enable players to play the game of basketball. In certain preferred aspects, the rim assembly is connected directly to the support arrangement so that force applied to the rim assembly is transmitted directly to the support assembly and is not transferred to the backboard assembly. |
| US08523714B2 |
Swing training and fitness aid
A swing training and fitness aid comprising a handle having an extended portion of rotational configuration engaged with a rotating means having flexibly affixed thereto a weight, the weight capable of being rotated along the extended portion in two directions by rotating said handle portion, thereby strengthening the wrists, forearms and shoulders of the user, along with exercising the abdominal muscles and the large muscle groups of the legs. |
| US08523713B2 |
Leg gloves with downward diagonal facing pocket openings
A leg glove having downward facing diagonal pockets for lifting a person who is jumping or being lifted, especially for lineouts in Rugby Union. A single piece of flexible, elastic material has a base layer formed in a conical section and a partially overlapping pocket layer that is folded back over the base layer and attached to form a pocket between the base layer and the pocket layer. |
| US08523704B2 |
Golf club heads with ribs and related methods
Golf club heads with ribs are described herein. Other embodiments and related methods are also disclosed herein. |