Document Document Title
US08455907B2 Semiconductor light emitting device having an optical plate including a meniscus control structure and method of manufacturing
A semiconductor light-emitting device and a method for manufacturing the same can include a wavelength converting layer in order to emit various colored lights including white light. The semiconductor light-emitting device can include a base board, a frame located on the base board, at least one light-emitting chip mounted on the base board, the wavelength converting layer located between an optical plate and each outside surface of the chips so as to extend toward the optical plate using a meniscus control structure, and a reflective material layer disposed at least between the frame and both side surfaces of the wavelength converting layer and the optical plate. The semiconductor light-emitting device can be configured to improve light-emitting efficiency and color variability between the light-emitting chips by using the reflective material layer as each reflector, and therefore can emit a wavelength-converted light having a high light-emitting efficiency from various small light-emitting surfaces.
US08455906B2 Semiconductor light-emitting device with improved light extraction efficiency
The present invention provides a semiconductor light-emitting device. The light-emitting device comprises a first conductive clad layer, an active layer, and a second conductive clad layer sequentially formed on a substrate. In the light-emitting device, the substrate has one or more side patterns formed on an upper surface thereof while being joined to one or more edges of the upper surface. The side patterns consist of protrusions or depressions so as to scatter or diffract light to an upper portion or a lower portion of the light-emitting device.
US08455898B2 LED device utilizing quantum dots
There is herein described a LED lighting device utilizing quantum dots in layers on top of an LED chip. The quantum dots layers and the LED chip are arranged with gradient refractive indices, so that the refractive index of each layer is preferably less than the refractive index of the immediately underlying layer or chip. The quantum dots with emission peaks at longer wavelengths are preferably arranged in lower layers closer to the LED chip; while the quantum dots with emission peaks at shorter wavelengths are arranged in higher layers farther from the LED chip.
US08455894B1 Photonic-crystal light emitting diode and method of manufacture
A high efficiency photonic-crystal light emitting diode comprises a flip-chipped stack of AlxInyGa1-x-yN layers, where 0≦x, y, x+y≦1. Each layer has a high crystalline quality, with a dislocation density below about 105 cm−2. The backside of the stack, exposed by removal of the original substrate, has a photonic crystal pattern for improved light extraction.
US08455891B2 Light emitting device package and light unit including the same
An LED package includes a body; a first lead frame having a first cavity in the body; a second lead frame having a second cavity in the body; a first bonding part protruding into a region between a first lateral side of the body and the first cavity from the first lead frame; a second bonding part protruding into a region between a second lateral side of the body, and the second cavity from the second lead frame; a first LED in the first cavity; a second LED in the second cavity; a third lead frame disposed between the first lateral side and the first cavity; a fourth lead frame disposed between the second lateral side and the second cavity; a first protective device on one of the third lead frame and the first bonding part; and a second protective device on one of the fourth lead frame and the second bonding part.
US08455887B2 LED illumination device for reducing occurrence of color heterogeneity
An LED illumination device includes: a substrate; one or more red LED chips arranged on the substrate; a plurality of blue LED chips arranged on the substrate; and a plurality of third-color LED chips arranged on the substrate. Respective centers of the red LED chips are arranged on a circumference of a first circle having as its center a point on the substrate, respective centers of the blue LED chips being arranged on the circumference of a second circle concentric with and greater than the first circle, respective centers of the third-color LED chips being arranged in a region between the first circle and the second circle.
US08455886B2 Light emitting device using GaN LED chip
A light emitting device is constituted by flip-chip mounting a GaN-based LED chip. The GaN-based LED chip includes a light-transmissive substrate and a GaN-based semiconductor layer formed on the light-transmissive substrate, wherein the GaN-based semiconductor layer has a laminate structure containing an n-type layer, a light emitting layer and a p-type layer in this order from the light-transmissive substrate side, wherein a positive electrode is formed on the p-type layer, the electrode containing a light-transmissive electrode of an oxide semiconductor and a positive contact electrode electrically connected to the light-transmissive electrode, and the area of the positive contact electrode is half or less of the area of the upper surface of the p-type layer.
US08455885B2 Method for heteroepitaxial growth of high-quality N-face gallium nitride, indium nitride, and aluminum nitride and their alloys by metal organic chemical vapor deposition
Methods for the heteroepitaxial growth of smooth, high quality films of N-face GaN film grown by MOCVD are disclosed. Use of a misoriented substrate and possibly nitridizing the substrate allow for the growth of smooth N-face GaN and other Group III nitride films as disclosed herein. The present invention also avoids the typical large (μm sized) hexagonal features which make N-face GaN material unacceptable for device applications. The present invention allows for the growth of smooth, high quality films which makes the development of N-face devices possible.
US08455882B2 High efficiency LEDs
A light emitting device and method of fabricating the same is disclosed that comprises at least one light emitter comprising an active region which emits light. The device further comprising a submount arranged such that the at least one light emitter is mounted to the submount such that the active region is angled in relation to the submount.
US08455877B2 Thin film transistor array substrate
A thin film transistor (TFT) array substrate includes a stack structure disposed to raise an extended electrode of a drain electrode of a thin film transistor. Therefore, a contact hole does need to be very deep to expose the extended electrode of the drain electrode.
US08455876B2 Organic light emitting diode display and method of manufacturing the same
An OLED display including a substrate main body; a first gate electrode and a second semiconductor layer; a gate insulating layer on the first gate electrode and the second semiconductor layer; a first semiconductor layer and a second gate electrode overlying the first gate electrode and the second semiconductor layer, respectively; etching stopper layers contacting portions of the first semiconductor layer; an interlayer insulating layer on the first semiconductor layer and the second gate electrode and including contact holes exposing the plurality of etching stopper layers, respectively; a first source electrode and a first drain electrode on the interlayer insulating layer and the contact holes being indirectly connected to the first semiconductor layer via the etching stopper layers or directly connected to the first semiconductor layer; and a second source electrode and a second drain electrode on the interlayer insulating layer being connected to the second semiconductor layer.
US08455875B2 Embedded DRAM for extremely thin semiconductor-on-insulator
A node dielectric and a conductive trench fill region filling a deep trench are recessed to a depth that is substantially coplanar with a top surface of a semiconductor-on-insulator (SOI) layer. A shallow trench isolation portion is formed on one side of an upper portion of the deep trench, while the other side of the upper portion of the deep trench provides an exposed surface of a semiconductor material of the conductive fill region. A selective epitaxy process is performed to deposit a raised source region and a raised strap region. The raised source region is formed directly on a planar source region within the SOI layer, and the raised strap region is formed directly on the conductive fill region. The raised strap region contacts the raised source region to provide an electrically conductive path between the planar source region and the conductive fill region.
US08455872B2 Electronic devices having plastic substrates
A method of manufacturing a thin film electronic device comprises applying a first plastic coating (PI-1) directly to a rigid carrier substrate (40) and forming thin film electronic elements (44) over the first plastic coating. A second plastic coating (46) is applied over the thin film electronic elements with electrodes (47) on top, with a portion lying directly over the associated electronic element, spaced by the second plastic coating. The rigid carrier substrate (40) is released from the first plastic coating, by a laser release process. This method enables traditional materials to be used as the base for the electronic element manufacture, for example thin film transistors. The second plastic coating can form part of the known field shielded pixel (FSP) technology.
US08455871B2 Thin film transistor array panel and method for manufacturing the same
A thin film transistor array panel is provided and includes a gate line, a gate insulating layer covering the gate line, a semiconductor layer disposed on the gate insulating layer, and a data line and a drain electrode disposed on the semiconductor layer. The data line and the drain electrode have a dual-layered structure including a lower layer and an upper layer with the lower layer having a first portion protruded outside the upper layer and the semiconductor layer having a second portion protruded outside the edge of the lower layer.
US08455861B2 Graphene based switching device having a tunable bandgap
A method of implementing bandgap tuning of a graphene-based switching device includes subjecting a bi-layer graphene to an electric field while simultaneously subjecting the bi-layer graphene to an applied strain that reduces an interlayer spacing between the bi-layer graphene, thereby creating a bandgap in the bi-layer graphene.
US08455860B2 Reducing source/drain resistance of III-V based transistors
An integrated circuit structure includes a substrate; a channel layer over the substrate, wherein the channel layer is formed of a first III-V compound semiconductor material; a highly doped semiconductor layer over the channel layer; a gate dielectric penetrating through and contacting a sidewall of the highly doped semiconductor layer; and a gate electrode on a bottom portion of the gate dielectric. The gate dielectric includes a sidewall portion on a sidewall of the gate electrode.
US08455858B2 Semiconductor structure for reducing band-to-band tunneling (BTBT) leakage
A semiconductor structure is provided. The semiconductor structure may include a substrate (100); a buffer layer or an insulation layer (200) formed on the substrate; a first strained wide bandgap semiconductor material layer (400) formed on the buffer layer or the insulation layer; a strained narrow bandgap semiconductor material layer (500) formed on the first strained wide bandgap semiconductor material layer; a second strained wide bandgap semiconductor material layer (700) formed on the strained narrow bandgap semiconductor material layer; a gate stack (300) formed on the second strained wide bandgap semiconductor material layer; and a source and a drain (600) formed in the first strained wide bandgap semiconductor material layer, the strained narrow bandgap semiconductor material layer and the second strained wide bandgap semiconductor material layer respectively.
US08455850B2 Extreme ultraviolet light source apparatus and method of generating extreme ultraviolet light
An extreme ultraviolet light source apparatus, which is to generate an extreme ultraviolet light by irradiating a target with a main pulse laser light after irradiating the target with a prepulse laser light, the extreme ultraviolet light source apparatus comprises: a prepulse laser light source generating a pre-plasma by irradiating the target with the prepulse laser light while a part of the target remains, the pre-plasma being generated at a different region from a target region, the different region being located on an incident side of the prepulse laser light; and a main pulse laser light source generating the extreme ultraviolet light by irradiating the pre-plasma with the main pulse laser light.
US08455849B2 Method and apparatus for modulating wafer treatment profile in UV chamber
A method and apparatus for providing a uniform UV radiation irradiance profile across a surface of a substrate is provided. In one embodiment, a substrate processing tool includes a processing chamber defining a processing region, a substrate support for supporting a substrate within the processing region, an ultraviolet (UV) radiation source spaced apart from the substrate support and configured to transmit ultraviolet radiation toward the substrate positioned on the substrate support, and a light transmissive window positioned between the UV radiation source and the substrate support, the light transmissive window having an optical film layer coated thereon. In one example, the optical film layer has a non-uniform thickness profile in a radial direction, wherein a thickness of the optical film layer at the peripheral area of the light transmissive window is relatively thicker than at the center region of the optical film layer.
US08455847B2 Mask health monitor using a faraday probe
In an ion implanter, an ion current measurement device is disposed behind a mask co-planarly with respect to a surface of a target substrate as if said target substrate was positioned on a platen. The ion current measurement device is translated across the ion beam. The current of the ion beam directed through a plurality of apertures of the mask is measured using the ion current measurement device. In this manner, the position of the mask with respect to the ion beam as well as the condition of the mask may be determined based on the ion current profile measured by the ion current measurement device.
US08455846B2 Method for making structures with improved edge definition
A method includes scanning a radiation beam with respect to a multi-photon curable photoreactive composition. The radiation beam includes a power sufficient to at least partially cure a volume of the multiphoton curable photoreactive composition. The method further includes modifying a characteristic of the radiation beam as the radiation beam is scanned.
US08455845B2 Method for detecting drag reducer additives in gasoline
A method for detecting polymer-based drag reducer additives in gasoline includes placing a sample in a high UV-transmittance receptacle having at least two transparent adjacent sides and irradiating the same with a pulsed laser beam; detecting laser-induced fluorescence wavelength resolved spectrum at a 90° angle relative to the laser beam through the adjacent side of the receptacle and a slit in a diffraction screen adjusting the position of the receptacle and de-focusing the collimating lenses so that the low resolution fluorescence wavelength-resolved spectrum appears with a first peak at about 380 nm and a second peak at about 430 nm; recording the laser-induced fluorescence wavelength-resolved spectra within a defined time-gate starting at the end of the temporal span of the laser pulse; and comparing the percentage intensity of the first peak relative to the second peak to that of a gasoline sample free of any polymer-based drag reducer additives.
US08455835B2 Radiation detection device
A radiation detection system for detecting the presence and location of a radiation source includes an optical fiber bundle having fibers of different lengths, a radiation sensitive material, a stimulating source and an optical detector. The stimulating source stimulates the radiation sensitive material and the radiation sensitive material releases a light output, while the light output provides a readout signal for each fiber corresponding in intensity to the radiation received from the radiation source. The optical detector receives the readout signal such that the variations in intensity of the readout signals along the length of the bundle determine the presence and general location of the radiation source.
US08455831B2 Sensing assembly having an oblique viewing angle range and methods of assembling, mounting and orienting the same
Disclosed herein is a sensing assembly. The assembly includes a sensing assembly housing for enclosing an interior. The assembly further includes a plurality of sensing assembly components which are at least partially positioned, or at least partially contained, within the interior. And the assembly includes an indicator lens device which is integral with, or integrated with respect to the housing. In at least some embodiments, at least a portion of the housing coincides at least in part with a first axis and at least a portion of the indicator lens coincides with a second axis, such that the first axis and the second axis intersect to form an oblique viewing angle range and at least a portion of the indicator lens device is visible at least substantially throughout the oblique (e.g., obtuse) viewing angle range.
US08455826B2 Variable aperture mechanism retention device
According to one embodiment, an optical device includes a variable aperture mechanism configured on a structure having a radiation detector that receives radiation through an aperture of the variable aperture mechanism. The aperture is selectively movable from a first position to a second position in which the aperture has a different size relative to the aperture in the first position. The structure is configured with one or more magnets that function with one or more magnetically permeable members configured on the variable aperture mechanism to hold the variable aperture mechanism in at least one position using a magnetic force between the magnets and magnetically permeable members.
US08455821B2 Method for S/TEM sample analysis
An improved method and apparatus for S/TEM sample preparation and analysis. Preferred embodiments of the present invention provide improved methods for TEM sample creation, especially for small geometry (<100 nm thick) TEM lamellae. Preferred embodiments of the present invention also provide an in-line process for S/TEM based metrology on objects such as integrated circuits or other structures fabricated on semiconductor wafer by providing methods to partially or fully automate TEM sample creation, to make the process of creating and analyzing TEM samples less labor intensive, and to increase throughput and reproducibility of TEM analysis.
US08455818B2 Mass spectrometry data acquisition mode for obtaining more reliable protein quantitation
Described herein are methods and systems which enable a unique platform for analyte quantitation. The methods and systems relate to determining the amount of interference in a precursor ion isolation window resulting from an impurity. Once the level of impurity is determined, several methods can be employed to reduce the amount of interference in a subsequent MS/MS spectrum. The methods and systems described herein enable increased quantitation accuracy while maintaining high levels of throughput.
US08455811B2 Light guide array for an image sensor
An image sensor pixel that includes a photoelectric conversion unit supported by a substrate and an insulator adjacent to the substrate. The pixel includes a light guide that is located within an opening of the insulator and extends above the insulator such that a portion of the light guide has an air interface. The air interface improves the internal reflection of the light guide. Additionally, the light guide and an adjacent color filter are constructed with a process that optimizes the upper aperture of the light guide. These characteristics of the light guide eliminate the need for a microlens.
US08455809B2 Solid-state imaging device, imaging device and driving method of solid-state imaging device
It is possible to achieve compatibility between suppressing dark current caused by a leak phenomenon and ensuring element reliability in a CMOS solid-state imaging device. When a pixel using electrons as signal charge is driven, the negative voltage level of each of control signals adapted to pulse-drive transistors in the pixel is adjusted so that the longer the charge accumulation time, the higher the voltage level. Preferably, the negative voltage level is grounded (GND) when no signal charge is accumulated. The negative voltage level is increased only when the charge accumulation time is long, which is the case where dark current caused by a leak phenomenon becomes a problem. Therefore, it is possible to suppress stress on the pixels and the gate oxide film of their drive circuits and degradation of the transistor characteristics even if dark current is suppressed.
US08455807B2 Sunlight collector module having a light-guide element and a beam splitting element and a hybrid illumination system having the same
A sunlight collector module is disclosed, capable of collecting the sunlight from the sun for the illumination at a certain position, and of reflecting portion of the sunlight to a solar photovoltaic module. The disclosed sunlight collector module comprises: a base, a first reflective element disposed on the base, a second reflective element, a light-guide element, and a beam splitting element, wherein the second reflective element is disposed on a side, which is opposite to the base, of the first reflective element. Besides, the light-guide element disposed on a side, which is opposite to the second reflective element, of the first reflective element. In addition, the beam splitting element is disposed between the first reflective element and the light-guide element, for reflecting portion of the sunlight to the solar photovoltaic module. The non-reflected portion of the sunlight passes through the beam splitting element and enters the light-guide element.
US08455805B2 Two dimensional barcodes and mobile terminals
Processing a two dimensional (2D) barcode using a mobile telecommunications terminal having an image scanner includes obtaining a scanned image of the 2D barcode from the image scanner, decoding the image to obtain data, including a web address, and associating an identifier with the decoded web address, such that the identifier is identifiable by a remote proxy server to obtain information relating to the use of the barcode. A browser of the mobile terminal transmits a web page request including the decoded web address and the identifier. The web page request may be identified as originating from a 2D barcode at a server in a mobile telecommunications network. The request is received from a mobile terminal, an inserted identifier is identified in the request, and a record is saved, the record including an identifier of the mobile terminal or a user of the mobile terminal and the web page address.
US08455800B2 Helix heated hose
The helix heated hoses 10 and 12 use two features to increase the flexibility. The first feature is a braided-copper heating element 14, which has increased flexibility over the prior art solid copper heating element. The element is spiral wound around the hose and held in place with a moisture barrier 16. The second feature is the helix twist 18 located just before the point where the hoses 10 and 12 attach to the manifold 20. The helix feature is created with the helix support 22, which initiates the twist around 24 inches back from the point of termination. The helix feature works to reduce the moment of inertia about the neutral axis 26 of the two supply hoses 10 and 12.
US08455799B2 Control panel for a cooking device
A control panel for controlling the operation of hotplates situated on a cooking appliance. The control panel has a translucent plate that permits the location of operating elements to be visually displayed on a top surface thereof only when lighting elements associated with the operating elements are energized. The lighting elements are selectively energized and/or de-energized so that only the operating elements of a particular hotplate are visible on the top surface of the translucent plate while a user is in the process of selecting or otherwise altering an operating parameter of the particular hot plate.
US08455798B2 Oven
The present invention relates to an oven (1) comprising a cooking chamber (2) wherein the cooking process is performed, a heater (3) for cooking the foodstuffs emplaced in the cooking chamber (2), a thermostat that controls the operation of the heater (3) and a control unit (4) that regulates the cooking parameters of temperature and duration such that energy savings is maintained at different temperature values (T1) defined by the user such as 160° C., 180° C., 200° C., 220° C., . . . according to type of food to be cooked.
US08455797B2 High-speed cooking oven with optimized cooking efficiency
The present invention is directed to improving the conventional high-speed cooking oven based on a combination of hot air impingement and microwave heating by providing a time-dependent spatial variation in the net air impingement and/or net microwave energy applied to the food product in the oven. This is aimed at optimizing heat transfer and microwave efficiencies in a high-speed cooking oven, thereby enabling the oven to deliver an optimal cooking efficiency in comparison to the conventional high-speed cooking oven. In addition, under the embodiments of the present invention, the cooking efficiency may be further optimized by providing a plenum between each wall of the cooking chamber and the housing of the oven.
US08455796B2 Hair styling iron with retractable fins
A heated flat iron 1 includes a first elongated member 2 and a second elongated member 3 that are joined together at one end at a hinge 4. An electrical cord 5 is attached thereto and has a conventional plug (not shown) to connect the iron 1 to a conventional external electrical energy source. An upper plate 6 is attached to the first member 2, and a lower plate 7 us attached to the second member 3. The upper plate 6 comprises a longitudinally aligned groove 8, preferably including in the groove 8 a series of longitudinally spaced laterally oriented slot depressions 9. The lower plate 7 includes a set of raised ridges 10, each having a length L that is transverse to the longitudinal axis of the second member 3, a height H measured in a direction extending away from the surface of the lower plate 7, and a thickness T measured transversely to length L, where L is greater than T. The ridges 10 are aligned in a longitudinally extending row along the lower plate 7 so that the row is aligned with the groove 8 and each ridge 10 corresponds in alignment with one of the slot depressions 9. The height of the ridges 10 may be adjustably varied.
US08455793B2 Laser shock peening
An embodiment of an apparatus for laser shock peening a treatment region of a metallic member includes a base oriented along a longitudinal axis; an engagement member actuable to engage a surface of the metallic member, the base in connection with engagement member; and a laser peening head adapted to emit laser radiation disposed with the base, the laser peening head moveable relative to the longitudinal axis.
US08455789B2 Energy collection and power reduction in laser coupling process
An energy collector is used to assist a laser coupling process by reducing the amount of output power of a laser that is used to modify a device attaching element. The energy collector includes an energy collector tip configured to be placed proximate to a device attaching element during the laser coupling process. The energy collector tip is configured to receive laser energy reflected from the device attaching element during the laser coupling process and is formed from a material that converts this reflected energy to heat. Sufficient thermal coupling is created between the energy collector and a surface to provide a conductive pathway for the energy, which has been converted to heat, between the energy collector and the device attaching element.
US08455778B2 Side key assembly for portable electronic device
A side key assembly includes a metallic dome, an insulating layer and a decorative layer. The insulating layer is laminated on the dome. The decorative layer is laminated on the insulating layer.
US08455774B2 Electronic apparatus
In an electronic apparatus, a first switch and a second switch are located in a correspondence relationship with each other. The first switch is configured to obtain an electric output by causing a first contact and a second contact to contact each other with an operation member. The second switch is configured to obtain an electric output by deforming a dome-shaped plate spring covering a third contact. The electronic apparatus includes a supporting member configured to keep a gap between the first contact and the second contact constant and to regulate the first switch and the second switch to be located on an approximately same line with respect to an operation direction of the operation member.
US08455767B2 Printed circuit board module
As a base, a side wall, and a top board are integrated by integral molding in a printed circuit board module, the printed circuit board module is structured in a simple manner. Further, conductive terminals are used for fitting a printed circuit board. The printed circuit board is securely held between the electrically conductive terminals and the top board via an elasticity of the conductive terminals. Here, due to the functioning of the notches, the printed circuit board is positioned in a simple manner. Due to the functioning of the base, a printed circuit board module can stand erect. The printed circuit board establishes a vertical posture. The packaging area is reduced. The packaging density improves. Further, the flat surface of the top board that is formed facing upward with a certain extension is used as, for example, an absorbent face.
US08455764B2 Support bracket
A support bracket for supporting insulating rods inside an insulator tube of a hollow core insulator. The support bracket includes a cylindrical ring with an outer surface for abutting against the inner surface of an insulator tube, an inner surface for supporting an insulating rod and two opposing end sides, denominated by first and second end sides. The support bracket includes an expansion assembly configured to be actuated so as to expand the cylindrical ring in at least one radial direction when the support bracket has been inserted in an insulator tube of a live tank circuit breaker.
US08455762B2 High performance telecommunications cable
A telecommunications cable comprising four twisted pairs of conductors and a separator spline comprised of a principal dividing strip and a first subsidiary dividing strip attached longitudinally along a first side of the principal dividing strip and a second dividing strip attached longitudinally along a second side of the principal dividing strip, the spline separating the four twisted pairs such that they are arranged in a staggered configuration. A method for reducing cross talk between adjacent cables in a telecommunications system, the method comprising the steps of, for each of the cables, providing a plurality of twisted pairs of conductors, winding an elongate filler element around the twisted pairs and covering the twisted pairs and the element with a cable jacket, the element introducing a visible distortion into an outer surface of the jacket.
US08455751B2 Thermoelectric devices and applications for the same
High performance thin film thermoelectric couples and methods of making the same are disclosed. Such couples allow fabrication of at least microwatt to watt-level power supply devices operating at voltages greater than one volt even when activated by only small temperature differences.
US08455747B2 Musical learning aid
A musical learning aid that help users learn and understand how musical pieces are composed. The present invention is able to help users understand how scales and chords are constructed. Additionally, the present invention can teach users which chords naturally lead to other notes allowing users to learn how to compose their own musical pieces.
US08455744B2 Adjustable magnetic guitar or similar stringed instrument support
An improved adjustable stringed instrument apparatus, hereafter known as ‘support’, ‘instrument support’ or ‘guitar support’, that supports the instrument in playing position while the user is in the sitting position. The support attaches to the instrument using magnets and rests on the user's leg. It utilizes a flexible leg support means connected to a magnetic attachment means, also referred to as the magnet housing, at one end and an adjustable rigid support with hinged pivoting magnet housing on the opposing end. Three discrete mechanisms on the support allow for vertical, horizontal, and angular adjustments of the instrument. The support's design allows it to be easily attached, removed, collapsed, and stored with no detrimental effects to the instrument. It also allows the support to be securely attached to a variety of imperfect surfaces.
US08455740B2 Potato cultivar ‘FL 2204’
A potato cultivar designated ‘FL 2204’ is disclosed. The invention relates to the tubers of potato cultivar ‘FL 2204’, to the seeds of potato cultivar ‘FL 2204’, to the plants of potato ‘FL 2204’, to the plant parts of potato cultivar ‘FL 2204’ and to methods for producing a potato plant produced by crossing potato cultivar ‘FL 2204’ with itself or with another potato variety. The invention also relates to methods for producing a potato plant containing in its genetic material one or more transgenes and to the transgenic potato plants and plant parts produced by those methods. This invention also relates to potato cultivars or breeding cultivars and plant parts derived from potato variety ‘FL 2204’, to methods for producing other potato cultivars, lines or plant parts derived from potato cultivar ‘FL 2204’ and to the potato plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid potato tubers, seeds, plants and plant parts produced by crossing potato cultivar ‘FL 2204’ with another potato cultivar.
US08455739B2 Pepper hybrid PX11334879
The invention provides seed and plants of pepper hybrid PX11334879 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of pepper hybrid PX11334879 and the parent lines thereof, and to methods for producing a pepper plant produced by crossing such plants with themselves or with another pepper plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
US08455738B2 Pepper hybrid PS09956434
The invention provides seed and plants of pepper hybrid PS09956434 and the parent lines thereof, such as line SMY 99-1311. The invention thus relates to the plants, seeds and tissue cultures of pepper hybrid PS09956434 and the parent lines thereof, and to methods for producing a pepper plant produced by crossing such plants with themselves or with another pepper plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
US08455737B2 Pepper hybrid PS09967422
The invention provides seed and plants of pepper hybrid PS09967422 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of pepper hybrid PS09967422 and the parent lines thereof, and to methods for producing a pepper plant produced by crossing such plants with themselves or with another pepper plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
US08455736B2 Pepper hybrid PS09967922
The invention provides seed and plants of pepper hybrid PS09967922 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of pepper hybrid PS09967922 and the parent lines thereof, and to methods for producing a pepper plant produced by crossing such plants with themselves or with another pepper plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
US08455734B2 Bean line EX 08071301
The invention provides seed and plants of the bean line designated EX 08071301. The invention thus relates to the plants, seeds and tissue cultures of bean line EX 08071301, and to methods for producing a bean plant produced by crossing a plant of bean line EX 08071301 with itself or with another bean plant, such as a plant of another line. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of a plant of bean line EX 08071301, including the pods and gametes of such plants.
US08455730B1 Soybean cultivar 14172101
A soybean cultivar designated 14172101 is disclosed. The invention relates to the seeds of soybean cultivar 14172101, to the plants of soybean cultivar 14172101, to the plant parts of soybean cultivar 14172101, and to methods for producing progeny of soybean cultivar 14172101. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 14172101. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 14172101, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 14172101 with another soybean cultivar.
US08455725B2 Soybean variety A1023969
The invention relates to the soybean variety designated A1023969. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1023969. Also provided by the invention are tissue cultures of the soybean variety A1023969 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1023969 with itself or another soybean variety and plants produced by such methods.
US08455724B2 Soybean variety A1023941
The invention relates to the soybean variety designated A1023941. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1023941. Also provided by the invention are tissue cultures of the soybean variety A1023941 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1023941 with itself or another soybean variety and plants produced by such methods.
US08455717B2 Collagen producing plants and methods of generating and using same
A method of producing collagen in a plant and plants producing collagen are provided. The method is effected by expressing in the plant at least one type of a collagen alpha chain in a manner enabling accumulation of the collagen alpha chain in a subcellular compartment devoid of endogenous P4H activity, thereby producing the collagen in the plant.
US08455710B2 Conductive wound dressings and methods of use
Wound treatment dressings comprising combinations of at least one conductive layer, at least one absorbent layer or a moisture regulation layer, and methods of making and methods of use are disclosed for treatment of wounds in humans and animals. The novel dressings aid in healing by helping restore the transepithelial potential of the skin, providing a functional anti-microbial barrier, and allowing for regulation of the moisture content of the wound without disturbing the wound.
US08455706B2 Method of making linear alkylbenzenes
A method of producing a linear alkylbenzene that includes introducing an olefin into an aromatic stream to form a mixture; processing the mixture in a shear device at a shear rate greater than about 20,000 s−1 to form a dispersion; and reacting the dispersion in the presence of a catalyst in a reactor vessel to form a linear alkylbenzene product stream, wherein the reactor vessel is maintained at a bulk reaction temperature in the range of about 0° C. to about 60° C.
US08455703B2 Use of ionic liquids with tetracyanoborate anions as a solvents for extraction of alcohols from aqueous solutions
The invention relates to a method for the liquid-liquid extraction of alcohols from aqueous solutions using at least one ionic liquid containing a tetra-cyanoborate anion as solvent.
US08455702B1 Cobalt and tin catalysts for producing ethanol
The present invention relates to a process for the formation of ethanol from a mixed feed, the steps of the process comprising: contacting a feed stream containing the mixed feed and hydrogen at an elevated temperature with a hydrogenation catalyst comprising from 3 to 25 wt. % of a substantially equal molar ratio of cobalt and tin on a support, wherein the mixed feed comprises 5 to 40 wt. % ethyl acetate and 60 to 95 wt. % acetic acid.
US08455700B2 Method for producing phenylalkane-1-ols
The present invention relates to a process for preparing phenylalkan-1-ols in three stages, where an ester condensation in the presence of alkali metal or alkaline earth metal alcoholates is carried out in the first stage.
US08455699B2 Production and separation of glycerol-related products using various feed stocks
Disclosed are processes for producing glycerol-related products. One process for producing glycerol-related products comprises introducing glycerol and an alkylation reagent to a substantially oxygen free environment. Another process for producing glycerol-related products comprises introducing a glycerol and tetramethylammonium hydroxide to a substantially oxygen free environment.
US08455694B2 Gelling agent and gel
A compound represented by the following formula (1) is provided as a gelling agent for gelatinizing a liquid organic compound: wherein n and m are each independently an integer of 2 to 18, R1 and R3 are each independently a single bond or a branched or linear alkylene group having 1 to 6 carbon atoms, R2 is a branched or linear alkylene group having 3 to 18 carbon atoms, and Z1 and Z2 are each independently a phenylene group or a biphenylene group.
US08455690B2 Method for producing arylhydroxylamine
The invention provides a method for producing an arylhydroxylamine compound efficiently and safely under mild conditions. The method involves contacting a nitroaryl compound with a hydrogen source in the presence of a platinum catalyst supported on amino group-coordinated silica and a poisoning agent.
US08455684B2 Method for converting aromatic aldehydes to aromatic acyl halides
A method for converting an aromatic aldehyde or a mixture of aromatic aldehydes to a reaction product in a reaction medium that is free from xylene. The reaction product may be an aromatic acyl halide or a mixture of aromatic acyl halides. The method includes bringing the aromatic aldehyde or mixture of aromatic aldehydes in contact with a halogen to obtain the reaction product.
US08455682B2 Method for the production of aminodicarboxylic acid-N,N-diacetic acids
Provided is a method for the production of aminodicarboxylic acid N,N-diacetic acids of formula (I), wherein X is independently hydrogen or an alkali metal and n is 1 or 2. Aminodicarboxylic acid-N,N-diacetic acids of high purity can be yielded. The method involves: a) reacting an aminodicarboxylic acid, with 0.8 to 1.2 mole equivalents of formaldehyde and with 0.8 to 1.2 mole equivalents of hydrocyanic acid; b) reacting the reaction products of a) with 0.8 to 1.2 mole equivalents of hydrocyanic acid and with 0.8 to 1.2 mole equivalents of formaldehyde; c) hydrolyzing in the reaction product obtained in b).
US08455679B2 Prepolymer systems having reduced monomeric isocyanate contents
A prepolymer system has a monomeric isocyanate content of no greater than about 10% by weight based on 100 parts by weight of the prepolymer system. The prepolymer system comprises a diluent component and a prepolymer component different than and separate from the diluent component. The diluent component has an excess of isocyanate (NCO) functional groups, and comprises the reaction product of a monohydric isocyanate-reactive component and an excess of a first isocyanate component. The first isocyanate component comprises monomeric isocyanates reactive with the monohydric isocyanate-reactive component. The prepolymer component also has an excess of NCO functional groups, and comprises the reaction product of a polyol component and an excess of a second isocyanate component. The prepolymer system can be used to prepare foams via reaction with water. The foams have low density and have excellent adhesion and sound dampening properties for use in cavities of automobile bodies.
US08455675B2 Solution component recovery method, solution component recovery apparatus, and impregnation process/impregnation component recovery system
A solution component recovery method, a solution component recovery apparatus, and an impregnation process/impregnation component recovery system for separating a first component from a second component. The separation between the first and second components is accomplished by reducing the pressure on a solution that contains the first component, which results in the solidification of the first component in the solution at a temperature that is equal to or higher than a predetermined solidification temperature. The second component, in which the first component is dissolved, is evaporated at a temperature range that is less than the predetermined solidification temperature. The evaporated second component is then recovered by a cooling step.
US08455669B2 Process for extracting fatty acids from aqueous biomass in a membrane contactor module
The present invention relates to a new process for extracting fatty acids from aqueous biomass in a membrane contactor module. The present invention also relates to an integrated process combining biomass concentration and/or diafiltration and fatty acid extraction in said membrane contactor module.
US08455664B2 Process for preparing 1-alkyl-3-difluoromethyl-5-hydroxypyrazoles
The present invention relates to a process for preparing 1-alkyl-3-difluoromethyl-5-hydroxypyrazoles, which are valuable intermediates for the production of fungicides.
US08455662B2 Formulations for benzimidazolyl pyridyl ethers
Formulations are provided, comprising: a compound of Formula I, a pharmaceutically acceptable salt thereof, or a mixture of any two or more thereof; and an ingredient selected from a hydrophilic solvent, a lipophilic solvent, an emulsifier, or a mixture of any two or more thereof; wherein the compound of Formula I is: In some embodiments, the formulations are liquids. In other embodiments, the formulations are solids. Also provided are methods of preparing such formulations.
US08455661B2 Catalysts containing N-heterocyclic carbenes for enantioselective synthesis
Novel N-heterocyclic carbene ligand precursors, N-heterocyclic carbene ligands and N-heterocyclic metal-carbene complexes are provided. Metal-carbene complexes comprising N-heterocyclic carbene ligands can be chiral, which are useful for catalyzing enantioselective synthesis. Methods for the preparation of the N-heterocyclic carbene ligands and N-heterocyclic metal-carbene complexes are given.
US08455657B2 Process for the preparation of 3-alkylsulfinylbenzoyl derivatives
A process is described for the preparation of 3-alkylsulfinylbenzoyl derivatives of the formula (IIIa) by reaction of 3-alkylsulfinylbenzoic acids of the formula (Ib) with compounds of the formula (II) in the presence of a chlorinating agent and a base. In the formulae specified above, Y is a radical such as pyrazolyl and cyclohexanedionyl. R1, R2 and R3 are radicals such as halogen, nitro, cyano and alkyl.
US08455653B2 Hydroxy-6-heteroarylphenanthridines and their use as PDE4 inhibitors
Compounds of the formula Ia***** in which the substituents have the definitions provided in the specification, are novel, effective PDE4 inhibitors, useful in the treatment of psoriasis.
US08455652B2 Inhibitors for the soluble epoxide hydrolase
Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
US08455651B2 Nicotinic acid and picolinic acid derived near-infrared fluorophores
This invention relates to new fluorescent chemical entities, including fluorescent molecules that comprise a carboxyl or carbonyl functionalized pyridine moiety. This invention also relates to the corresponding reactive versions of such molecules. This invention also relates to the corresponding conjugates with moieties such as peptides, proteins, various biomolecules, carbocyclic and heterocyclic compounds, sugars, and their uses thereof.
US08455649B2 Insecticidal substituted azinyl derivatives
N-Azinyl-N′-aryl ureas and thioureas derivatives are effective at controlling insects.
US08455643B2 8-hydroxyquinoline-based white-light-emitting organic electroluminescent material
A white-light organic electroluminescent material based on 8-hydroxyquinoline and the method for preparing the same, as well as an organic light emitting diode including this material. The material may be the compound represented by the Formula (IX) having a DCDC group, a 5-position substituted 8-hydroxyquinolinyl group and a carbazolyl group as red light-, green light- and blue-light emitting groups, respectively. It exhibits a spectrum having a band width of 182.4 nm that substantially covers the visible-light region, and has a color coordinate of (0.3177, 0.3946), which just locates within the white-light area. Such a material is capable of realizing a white-light emission, and may be used in a white-light OLED as a single light-emitting layer, which can decrease the number of layers of the white-light OLED and thereby improve the luminous efficiency, stabilize the light color, lower the turn-on voltage and simplify the fabrication process.
US08455640B2 Process for statins and its pharmaceutically acceptable salts thereof
Novel process for statins and its pharmaceutically acceptable salts thereof represented by general formula (I).
US08455638B2 Soluble guanylate cyclase activators
A compound having the structure useful for treatment or prevention of cardiovascular diseases, endothelial dysfunction, diastolic dysfunction, atherosclerosis, hypertension, angina pectoris, thromboses, restenoses, myocardial infarction, strokes, cardiac insufficiency, pulmonary hypertonia, erectile dysfunction, asthma bronchiale, chronic kidney insufficiency, diabetes, or cirrhosis of the liver in a human or animal patient.
US08455635B2 Antisense oligonucleotides for inducing exon skipping and methods of use thereof
An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 202.
US08455629B2 Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors
Monoclonal antibodies and hybridomas producing them that interact with osteoprotegerin ligand (OPGL) are provided. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are also provided. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are further provided.
US08455625B2 Fusion protein of antibody L19 against fibronectin ED-B and interleukin 12
Conjugate for targeting therapeutic or diagnostic agent or drug to cells or tissues in a body, e.g. areas of neoplastic growth or angiogenesis. Use of conjugate for in vivo diagnosis or therapy e.g. inhibiting tumor growth or metastasis, inhibiting angiogenesis and/or treating cancer. Conjugate comprises therapeutic or diagnostic agent as oligomeric protein e.g. heterodimeric protein, wherein first and second subunits of protein are each conjugated to a specific binding member e.g. an antibody fragment such as scFv. Subunits of oligomer may be conjugated to specific binding members as fusion proteins. Conjugate may comprise IL-12 heterodimer having two subunits, each subunit fused to scFv L19 or TN11 for targeting IL-12 to extracellular matrix components associated with neoplastic growth and angiogenesis.
US08455624B2 Methods and compositions for detecting endometrial or ovarian cancer
Some embodiments of the present invention relate to methods and compositions for assessing the absence, presence, progression, or stage of cancer. In particular, methods and compositions for detecting endometrial cancer or ovarian cancer are provided.
US08455623B2 Compositions and methods for diagnosing and treating cancer
Isolated antibodies that specifically bind the human MET Receptor and inhibit MET signaling are described. Also described are methods of treating cancer, the methods comprising administering a therapeutically effective amount of the provided MET antibodies and combinations thereof.
US08455622B2 Variant target binding agents and uses thereof
The present invention provides variant target binding agents and methods relating to the use of such binding agents for the prophylaxis or treatment of cancers and immunological disorders. The variant target binding agent is conjugated to a therapeutic agent that exerts a cytotoxic, cytostatic, or immunomodulatory effect on target cells.
US08455620B2 Cloning and expression of a novel phytase
The present invention relates to a novel phytase enzyme, a novel isolated nucleic acid molecule coding the enzyme, and a novel Yersinia intermedia having phytase activity. Particularly, the present invention relates to the phytase having (a) Theoretical molecular weight 45.5 kDa, (b) high specific activity 3960±248 U/mg, (c) high stability at high temperature and wide pH, (d) optimal pH of 4.0-5.0, (e) optimal temperature of 50-60° C., (f) high resistance to pepsin and trypsin. The phytase is very suitable to be used in feed of monogastrics as feed additive. The present invention also relates to a recombinant vector comprising said nucleic acid molecule, a recombinant host cell (e.g., Pichia pastoris) harboring said recombinant vector, and a method for producing phytase using the recombinant host cell. The present invention further provides a feed additive comprising said phytase and/or host cells expressing a phytase as effective ingredient. In addition, the present invention provides a novel method for isolating phytase from a target organism.
US08455619B2 Polypeptide synthesis for drug delivery
The present invention provides improved methods for the synthesis of polypeptide or peptide-linked compounds via a NCA-based polymerization reaction that produces high product yields in much less time. Such improved methods are achieved by application of a higher temperature and/or reduced pressure to the reaction such that an NCA-containing monomer melts.
US08455618B2 Melanocortin receptor-specific peptides
The invention relates to melanocortin receptor-specific cyclic peptides of Formula (I) or a pharmaceutically acceptable salt thereof, where R1, R2, R3, R4a, R4b, R4c, R5, x and y are as defined in the specification. These compounds are particularly useful in the treatments of energy homeostasis and metabolism related (e.g. diabetes), food intake related and/or energy balance and body weight related diseases, disorders and/or conditions, including obesity, overweight and diseases, disorders and/or conditions associated with obesity and/or overweight, such as type 2 diabetes and metabolic syndrome.
US08455614B2 PMMA binding peptides
Peptides are provided that have binding affinity for polymethyl methacrylate (PMMA). The polymethyl methacrylate-binding peptides may be used to prepare peptide-based reagents suitable for use in a variety of applications. The peptide-based reagents may be used to couple benefit agents to a PMMA polymer surface or may be used to couple a benefit agent comprising a PMMA polymer surface to a target surface, such as a body surface.
US08455613B2 Reagents for directed biomarker signal amplification
Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.
US08455609B2 Castable polyurea formulation for golf ball covers
Golf balls having improved cut and shear resistance that include covers and/or other layers formed from polyurea compositions formed with at least one amine-terminated polytetramethylene ether glycol homopolymer, at least one amine-terminated copolymer of polytetramethylene ether glycol and polyalkylene glycol. The amine-terminated polytetramethylene ether glycol homopolymer or amine-terminated copolymer of polytetramethylene ether glycol and polyalkylene glycol may be used as the isocyanate-reactive in the prepolymer and/or the curing agent.
US08455607B2 Curable liquid composite light emitting diode encapsulant
A curable liquid polysiloxane/TiO2 composite for use as a light emitting diode encapsulant is provided, comprising: a polysiloxane with TiO2 domains having an average domain size of less than 5 nm, wherein the curable liquid polysiloxane/TiO2 composite contains 20 to 60 mol % TiO2 (based on total solids); wherein the curable liquid polysiloxane/TiO2 composite exhibits a refractive index of >1.61 to 1.7 and wherein the curable liquid polysiloxane/TiO2 composite is a liquid at room temperature and atmospheric pressure. Also provided is a light emitting diode manufacturing assembly.
US08455605B2 Resin composition for transparent encapsulation material and electronic device formed using the same
A resin composition for a transparent encapsulation material, the resin composition including a polysiloxane obtained by copolymerization of a first silicon compound represented by the following Chemical Formula 1 and a second silicon compound including a compound represented by the following Chemical Formula 2,
US08455603B2 Process for the preparation of amine-amide-functional siloxanes
The invention describes amine-amide-functional siloxanes and a process for the preparation thereof by the chemical reaction of SiOH-functional siloxanes with amino-functional silanes in the presence of carboxylic acid anhydrides.
US08455590B2 Modified triaroylbenzene-skeleton polymer
It is an object to provide a film having both high transparency and high heat resistance, and particularly a coating solution for forming a coating film from which an optical film can be produced. A triaroylbenzene-skeleton polymer in which a terminal of a polymer produced by polymerizing a compound of Formula [1] below is modified by a compound of Formula [2] below. A coating solution for forming a coating film, comprising the polymer. A film obtained from the coating solution for forming a coating film. In the formulae below, X1 is a divalent group of Formula [1a], Formula [1b], or Formula [1c] below (where Y1 and Y2 are independently a C1-2 alkylene group; n is an integer of 1 to 6; and m is an integer of 1 to 6), X2 is divalent benzene, thiophene, furan, or fluorine, and X3 is a hydrogen atom, a halogen atom, CF3, a C1-6 alkoxy group, or a C1-6 alkyl group.
US08455582B2 Tire rubber composition and pneumatic tire
It is an object of the present invention to provide a tire rubber composition excellent in performances such as silica dispersibility and processability. The present invention relates to a tire rubber composition, comprising: a rubber component; silica; and a silane coupling agent, wherein the silica has a CTAB specific surface area of 180 m2/g or more and a BET specific surface area of 185 m2/g or more, and the silane coupling agent is a copolymer comprising units A represented by formula (1) and units B represented by formula (2), and the proportion of the units B is 1 to 70 mol % of the total molar amount of the units A and the units B.
US08455580B2 Medium voltage cable insulation
Compositions comprising: A. Ethylene-based polymer, e.g., LDPE; B. Polyalkylene glycol, e.g., PEG; C. Tertiary hindered amine stabilizer; D. Sulphur-containing hindered phenol antioxidant; E. Peroxide; and F. Optional coagent are useful in the preparation of TRXLPE insulation for medium voltage cable that exhibits a commercially desirable balance of long term heat aging retardancy and water-tree resistance.
US08455575B2 Wood powder-containing material, method of manufacturing the same, and compact
A wood powder-containing material includes wood powder having a volume average particle diameter of from about 1 μm to about 5 mm, an aliphatic polyester, and a condensed phosphate ester.
US08455573B2 Curable composition comprising imidazolium monocarboxylate salt
Disclosed are curable epoxy compositions comprising imidazolium monocarboxylate salts as curing catalysts and method for curing same. The imidazolium monocarboxylate salt is suitable for use as latent catalysts that effect curing upon heating to a curing temperature threshold. The curable compositions prepared therefrom are used to prepare coated substrates, and to produce conformally sealed printed wiring boards. Of particular utility are curable compositions comprising 2-ethyl-4-methyl imidazolium monocarboxylate salts.
US08455570B2 Ink composition for continuous inkjet printing
An aqueous inkjet black ink composition for use in continuous ink jet printing is provided comprising black pigment particles dispersed with a polymeric dispersant or self dispersing pigment particles without the need for a dispersant; and at least one surfactant, wherein the at least one surfactant is selected to provide the ink composition with a 10-ms dynamic surface tension of less than 54 mN/m. The invention relates to continuous ink jet printing of an aqueous pigmented ink composition recycled from a main ink supply reservoir, employing a printer with a drop ejector and a drop deflector and a non-printing drop catcher capable of returning unprinted ink to the fluid delivery system following the capture of non-printing drops. The pigmented ink jet ink compositions provide for particularly suitable fluid properties on the drop catcher face that minimize printing defects that can occur during drop deflection during the printing of high dynamic range images at high speed.
US08455566B2 Materials leading to improved dental composites and dental composites made therefrom
Provided herein are uncured dental composites suitable for, among other things, filling cavities in teeth.
US08455563B2 Reactive mesogenic compounds and mixtures
The invention relates to new reactive mesogenic compounds (RM), polymerisable liquid crystal (LC) mixtures and polymers comprising them, and the use of the compounds, mixtures and polymers in optical, electrooptical, electronic, semiconducting or luminescent components or devices, in decorative, security or cosmetic applications, especially for use in polymer films having high optical dispersion.
US08455551B2 Broad spectrum disinfectant
A broad spectrum disinfectant includes a quaternary ammonium halogen, an alkaline agent, a chelating agent, a nonionic surfactant coupler, at least one alkoxylated nonionic surfactant, and water or any aliphatic alcohol. The disinfectant composition is phenol-free, is effective in eradicating microorganisms such as various fungi, and is stable to gamma-irradiation.
US08455549B2 Carbonylamino derivatives useful for the treatment of certain inflammatory disorders
The present invention relates to the use of a particular group of carbonylamino derivatives for the treatment or alleviation of a disease or condition relating to certain inflammatory disorders.
US08455546B2 Medicament having promoting action on hepatocyte proliferation
A medicament for promoting proliferation of hepatocytes and liver regeneration, which comprises a polyprenyl compound such as 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid as an active ingredient.
US08455545B2 Liquid pest control formulation
The present invention relates to a liquid pest control system that includes a synthetic pyrethroid as a pest control active ingredient and an agent selected from the group consisting of purified diethylene glycol monoethyl ether, tocopherol nicotinate and tocopherol succinate, and combinations thereof, to reduce or eliminate paresthesia of the synthetic pyrethroid. The system releases the synthetic pyrethroid efficiently and uniformly. The pest control system is less irritating to the animal's skin as compared to prior art systems, particularly to small breeds of dogs. The system is useful for making liquid spot-on treatments, sprays and the like.
US08455544B2 Synthetic triterpenoids and methods of use in the treatment of disease
The present invention concerns methods for treating and preventing renal/kidney disease, insulin resistance/diabetes, fatty liver disease, and/or endothelial dysfunction/cardiovascular disease using synthetic triterpenoids, optionally in combination with a second treatment or prophylaxis.
US08455536B2 Methods of using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline 1,3-dione
Stereomerically pure (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, substantially free of its (−) isomer, and prodrugs, metabolites, polymorphs, salts, solvates, hydrates, and clathrates thereof are discussed. Also discussed are methods of using and pharmaceutical compositions comprising the (+) enantiomer of 2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione are disclosed. The methods include methods of treating and/or preventing disorders ameliorated by the reduction of levels of TNF-α or the inhibition of PDE4.
US08455535B2 Heteroaryl dihydroindolones as kinase inhibitors
The present invention provides a compound represented by the formula: wherein ring systems A and B, and the variables R1, b, R6, Y, Z, X, R and a are defined in the specification. The compounds of the present invention may be used in a method for treating diseases related to unregulated tyrosine kinase signal transduction, such as cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders, and metabolic diseases.
US08455534B2 Estrogen receptor modulators and uses thereof
Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
US08455533B2 Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
US08455531B2 Amino acid compositions
An amino acid composition is disclosed. The composition includes: at least one constituent selected from the group consisting of a nitrate, a nitrite, and both; and at least one constituent amino acid selected from the group consisting of Arginine, Agmatine, Beta Alanine, Citrulline, Creatine, Glutamine, L-Histidine, Isoleucine, Leucine, Norvaline, Ornithine, Valine, Aspartic Acid, Cysteine, Glycine, Lysine, Methionine, Proline, Tyrosine, and Phenylalanine. Also disclosed are a method for increasing the bioabsorption of Amino Acids in a human or animal and a method for increasing vasodilative characteristics of Amino Acids in a human or animal.
US08455519B2 Drug active in neuropathic pain
The present invention relates to a compound of formula (I): in which: R is a linear or branched alkyl group containing between 1 and 3 carbon atoms, Y is CH or N, and p is an integer between 0 and 3 and preferably 0 and 1, and salts thereof, either acid-addition salts with a pharmaceutically acceptable organic or mineral acid, or base-addition salts with a pharmaceutically acceptable organic or mineral base. The invention also relates to a process for preparing the compound of formula (I), and to a pharmaceutical composition comprising it. The invention also relates to the use of an indazole for preparing a pharmaceutical composition that is active in the treatment of neuropathic pain.
US08455518B2 Method of treating skin with microRNA modulators
Methods for preventing, ameliorating, or reducing dermatological signs of aging are provided which employ active agents that suppress or down-regulate microRNA expression in dermal fibroblast, resulting in enhanced production of collagen, elastin and/or fibrillin in the skin. Also provided are methods for screening for activity against specific microRNAs and the methods of using active agents identified by the screening protocol in the treatment of skin.
US08455517B2 Method of using diketopiperazines and composition containing them
The invention provides a method of inhibiting the effects of platelet activating factor (PAF). For instance, a disease or condition mediated by PAF (particularly inflammation) can be treated or platelet aggregation can be inhibited. The invention also provides a method of inhibiting the production and/or release of interleukin 8 (IL-8) by cells. The effects of PAF and the production and/or release of IL-8 are inhibited according to the invention by a compound of the formula: wherein R1 and R2 are defined in the application, or a physiologically-acceptable salt thereof. The invention also provides pharmaceutical compositions comprising these compounds.
US08455516B2 HIV-1 fusion inhibitors and methods
A new series of HIV-1 fusion inhibitors and methods of use are disclosed. The compounds are based on a substituted indole, benzimidazole, indoline or isoindoline fragment. The compounds find use in inhibiting or preventing HIV fusion from occurring, thus inhibiting or preventing entry of viral RNA into host cells. The compounds may be useful towards other biological targets involving protein-protein interactions.
US08455515B2 Substituted 4-phenyltetrahydroisoquinolines, process for their preparation, pharmaceutical compositions and therapeutic use
The present invention relates to substituted 4-phenyltetrahydroisoquinoline compounds and pharmaceutical compositions comprising them which are excellent inhibitors of the sodium-hydrogen exchanger (NHE), in particular of the sodium-hydrogen exchanger of subtype 3 (NHE-3). As such these compounds are useful in the treatment of various disorders of the renal and respiratory systems such as acute or chronic renal failure, pulmonary complications, biliary function disorders, respiratory disorders such as snoring or sleep apneas and cardiovascular/central nervous system disorders such as stroke. More specifically, the present invention relates to substituted 4-phenyl-tetrahydroisoquinolines defined by the formula I in which R1-R8 are defined herein.
US08455510B2 Rapamycin carbonic ester analogues, pharmaceutical compositions, preparations and uses thereof
Rapalogs of formula I, pharmaceutically acceptable salts, pharmaceutical compositions, and preparation methods and uses thereof. The rapalogs have the structure of formula I and can be used as an anti-tumor medicament. Comparing with rapamycin, the rapalogs of the present invention exhibit enhanced water solubility, and improved pharmacological and pharmacokinetic properties by introducing a hydrophilic and polar group such as a hydroxyl.
US08455509B2 Method for the preparation of morphine compounds
The present invention relates to a method for the preparation of morphine compounds comprising a low content of α,β-unsaturated compounds, which comprises the steps of: (i) bringing the crude morphine compound into contact with a base, at a pH of greater than 13, under conditions which make possible the Michael addition reaction on the α,β-unsaturated compound(s) present; (ii) separating the morphine compound from the reaction mixture; and (iii) if appropriate, separating the addition product formed from the morphine compound. It also relates to a composition comprising at least 99% by dry weight of morphine compound or of a pharmaceutically acceptable salt thereof, and an α,β-unsaturated compound in a content of less than 100 ppm.
US08455507B2 Aminopyrimidines useful as kinase inhibitors
The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
US08455506B2 Quinazoline based EGFR inhibitors containing a zinc binding moiety
The present invention relates to quinazoline containing zinc-binding moiety based derivatives of Formula (I) below. These compounds have enhanced and unexpected properties as inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and are useful in the treatment of EGFR-TK related diseases and disorders such as cancer. These compounds may further act as HDAC inhibitors.
US08455502B2 Selective phosphodiesterase 9A inhibitors as medicaments for improving cognitive processes
The invention relates to the use of selective phosphodiesterase 9A (PDE9A) inhibitors for producing medicaments for improving perception, concentration, cognitive processes, learning and/or memory.
US08455498B2 Inhibitors of histone deacetylase
This invention comprises the novel compounds of formula (I) wherein n, R1, R2, R3, R4, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
US08455497B2 Inhibitors of aspartyl protease
The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting the activity of HIV aspartyl protease using the compounds of this invention and methods for screening compounds for anti-HIV activity.
US08455494B2 Preparations and methods for ameliorating or reducing presbyopia
This application relates to the use of one or more parasympathomimetic drugs in combination with one or more alpha agonists to create optically beneficial miosis to, for example, temporarily treat presbyopia. The invention provides a pharmaceutical preparation comprising a therapeutically effective amount of one or more parasympathomimetic drugs or cholinesterase inhibitors, or a pharmaceutically acceptable salt thereof, in combination with one or more alpha agonists or antagonists, or a pharmaceutically acceptable salt thereof. The invention further provides for a method for treating, ameliorating or reducing presbyopia of a patient having an eye, comprising administering to said eye a pharmaceutically effective amount of the ophthalmic preparation.
US08455493B2 Imidazopyrazine Syk inhibitors
Certain imidazopyrazines of Formula (I) and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample.
US08455492B2 Methods for treating retinal diseases
The present invention provides a method of providing neuroprotection to a mammal comprising administering to said mammal suffering from or at risk of suffering a noxious action on its nerve cells an effective amount of a compound of formula I to inhibit or prevent nerve cell injury or death wherein the 2-imidazolin-2-ylamino group is in either the 5- or 6-position of the quinoxaline nucleus; x, y and z are in any of the remaining 5-, 6-, 7- or 8-positions and are selected from hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl; and R is an optional substituent in either the 2- or 3-position of the quinoxaline nucleus and may be hydrogen, lower alkyl or lower alkoxy, or pharmaceutically acceptable salts thereof and mixtures thereof. Such noxious action may result from ischemia, e.g. spinal ischemia.
US08455489B2 Substituted pyrimidine compositions and methods of use
Novel compositions and methods of using substituted pyrimidines which have the general formula: (I).
US08455484B2 Selected inhibitors of protein tyrosine kinase activity
The invention provides new compounds and compositions thereof. The invention also provides methods for treating ophthalmic diseases, disorders and conditions.
US08455476B2 Azetidinyl diamides as monoacylglycerol lipase inhibitors
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein.
US08455473B2 Composition and method for irrigation of a prepared dental root canal
Composition and method for irrigating a prepared dental root canal. The composition is an aqueous composition of ethylenediamine tetraacetic acid, chlorhexidine or orally acceptable addition salt, and N-cetyl-N,N,N-trimethylammonium bromide, and is effective for simultaneous smear layer removal and disinfection.
US08455469B2 Use of norgestimate as a selective inhibitor of TRPC3, TRPC6 and TRPC7 ion channels
TRPC ion channels are non-selective channels widely expressed in human tissues. These channels are involved in numerous physiological functions and are putative targets for the development of novel medicines. There is a need to gain a better understanding of TRPC ion channels in cells and beyond. The present invention provides a pharmacological tool compound that allows to study TRPC ion channels due to its discriminating inhibition of TRPC subfamilies. In the present invention, norgestimate is shown to selectively inhibit TRPC3, TRPC6 and TRPC7.
US08455467B2 2-methylene-vitamin D analogs and their uses
This invention discloses 2-methylene-vitamin D analogs, and specifically (20S)-25-hydroxy-2-methylene-vitamin D3 and (20R)-25-hydroxy-2-methylene-vitamin D3, as well as pharmaceutical uses therefor. These compounds exhibit relatively high binding activity and pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent especially for the treatment or prevention of osteosarcoma, leukemia, colon cancer, breast cancer, skin cancer or prostate cancer. These compounds also have relatively high calcemic activities evidencing use in the treatment of bone diseases.
US08455466B2 Vitamin d analogues, compositions comprising said analogues and their use
Compounds according to formula I in which formula R1 and R2, which may be the same or different, represent halogen, (C1-C6)hydrocarbyl, optionally substituted with one or two hydroxyl group or one or more fluorine atoms, or, together with the carbon atom to which they are both attached, R1 and R2 form a (C3-C6)carbocyclic ring, or one of R1 and R2 taken together with R3 forms a direct bond, such that a triple bond is constituted, or R1 and R2 represent both hydrogen; R3 when not forming a direct bond with one of R1 and R2 represents hydrogen or (C1-C3)hydrocarbyl; X represents (E)-ethylene, (Z)-ethylene, ethynylene, or a bond; Y and Z independently represent hydrogen or methyl; and prodrugs and stereo isomeric forms thereof are provided together with their use in therapy, and their use in the manufacture of medicaments.
US08455464B2 Dextrin containing compositions for prevention of adhesions
A composition for the treatment of adhesions that are formed as a result of an inflammatory response comprising an aqueous formulation containing the polysaccharide dextrin in an effective amount. The invention also discloses a method of treating adhesions that are formed as a result of an inflammatory response.
US08455461B2 Compositions containing a synergic mixture of polyols and xyloglucanes as phytosanitary and bio-fertilising products
A eliciting composition including a synergistic mixture of at least one xyloglucan derivative and at least one polyol.
US08455460B2 Cosmetic composition containing one or more compounds of the β-(1,3)-glucuronan or β-(1,3)-glucoglucuronan type
The invention relates to a cosmetic composition that contains one or more compounds of the β-(1,3)-glucuronane or β-(1,3)-glucoglucuronane type as well as the pharmaceutically acceptable salt thereof, and to the use of this composition and these compounds for various cosmetic applications.
US08455454B2 miR 204, miR 211, their anti-miRs, and therapeutic uses of same
Embodiments of the invention provide methods of preventing or treating detrimental epithelial cell proliferation, loss of epithelial cell differentiation, age-related macular degeneration and/or proliferative vitreal retinopathy in an individual comprising administering to an individual in need thereof an effective amount of miR 204, an effective amount of miR 211, or an effective amount of a mixture of miR 204 and miR 211. A further embodiment of the invention provides a method of facilitating the transport of a substance across an epithelium in an individual comprising administrating to an individual an effective amount of anti-miR 204, an effective amount of anti-miR 211, or an effective amount of a mixture of anti-miR 204 and anti-miR 211. Additional embodiments of the invention include pharmaceutical compositions of miR 204 and/or miR 211 and pharmaceutical compositions of anti-miR 204 and/or anti-miR 211.
US08455450B2 Methods for obtaining a therapeutically effective amount of hematopoietic precursor cells and long term engraftment thereof
The present invention is directed to novel therapeutic uses of T-140 analog peptides and compositions comprising same. Specifically, the invention provides compositions and methods useful for providing improved bone marrow transplantation and in the treatment of other conditions wherein bone marrow depletion or suppression is involved.
US08455448B2 Myostatin isoform
The present invention provides splice variants of myostatin that promote muscle growth, and include polynucleotides and polypeptide sequences, constructs comprising the sequences and compositions for regulating muscle growth and treating diseases associated with muscle tissue. The splice variants include the consensus sequence X1 I F L E X2 X3 X4 Q X5 C S I L X6 X7 X8 X9 X10 wherein X1 is I or L, X2 is V or L, X3 is Y, C, G or S, X4 is I or F, X5 is F or L, X6 is G or E, X7 is E or V, X8 is A or T, X9 is A or V and X10 is absent, F or L. The present invention also provides for the use of the present sequences in identifying animals with altered muscle mass, and for use in selective breeding programs to produce animals with altered muscle mass.
US08455446B2 Single domain TDF-related compounds and analogs thereof for use in treating a tissue differentiation factor related disorder
The present invention relates generally to tissue differentiation factor (TDF) analogs. More specifically, the invention relates to structure-based methods and compositions useful in designing, identifying, and producing molecules which act as functional modulators of TDF-like receptors. The invention further relates to methods of detecting, preventing, and treating TDF-associated disorders.
US08455444B2 CDH3 peptide and medicinal agent comprising the same
The present invention provides a peptide of the following (A) or (B): (A) a peptide including an amino acid sequence of SEQ ID NO: 1 or 2; (B) a peptide including an amino acid sequence of SEQ ID NO 1 or 2, wherein one, two, or several amino acid(s) are substituted, deleted, inserted, and/or added, and wherein the peptide has an activity to induce killer T cells.
US08455442B2 Peptides having binding affinity to an antibody which recognizes an epitope on an α1 loop 2 or β2 loop 1 of an adrenoreceptor
A peptide having an ED50 of less than 500 nm, in particular 10 nM to an antibody which recognizes an epitope on an extracellular α1 loop 2 or β2 loop 1 of a human adrenoceptor wherein the antibody's binding to the epitope results in an increase of γ-secretase activity, an increased release of β-amyolid molecules and/or cellular dysfunction of cerebral blood vessel cells, glia cells or neurons, wherein the ED50 value is measured by bioassay.
US08455441B2 Antidotes for factor Xa inhibitors and methods of using the same
The present invention relates antidotes to anticoagulants targeting factor Xa. The antidotes are factor Xa protein derivatives that bind to the factor Xa inhibitors thereby substantially neutralizing them but do not assemble into the prothrombinase complex. The derivatives describe herein lack or have reduced intrinsic coagulant activity. Disclosed herein are methods of stopping or preventing bleeding in a patient that is currently undergoing anticoagulant therapy with a factor Xa inhibitor.
US08455440B2 Combination anticoagulant therapy with a compound that acts as a factor Xa inhibitor
The present invention is directed to methods of using combination therapies containing [2-({4-[(dimethylamino)iminomethyl]phenyl}carbonylamino)-5-methoxyphenyl]-N-(5-chloro(2-pyridyl))carboxamide for the treatment of thrombotic disease(s) and pharmaceutical compositions thereof.
US08455438B2 Natriuretic polypeptides for reducing or preventing restenosis
Materials and methods related to using natriuretic polypeptides to reduce proliferation of smooth muscle cells, and to reduce or prevent restenosis.
US08455436B2 Compositions and methods for treating joints
Methods and compositions are disclosed for an intra-articular injection for the treatment of osteoarthritis. The methods and compositions comprising combinations of hyaluronic acid and a bone morphogenetic protein, like rhGDF-5, can be useful for any synovial joint, including the knee, shoulder, hip, ankle, hands, spinal facet, or temporomandibular joint, both for the relief of pain and for slowing disease progression.
US08455433B2 Process for solubilizing glucagon-like peptide 1 compounds
Disclosed is a method of preparing a GLP-1 compound that is soluble in aqueous solution at pH 7.4 from a GLP-1 compound that is substantially insoluble in aqueous solution at pH 7.4. The insoluble GLP-1 compound is dissolved in aqueous base or in aqueous acid to form a GLP-1 solution. The GLP-1 solution is then neutralized to a pH at which substantially no amino acid racemization of the GLP-1 compounds occurs, after which the soluble GLP-1 compound is isolated from the neutralized solution.
US08455425B2 Particles containing alkali
The present invention relates to [1] alkali agent-containing particles which are free from deterioration of dissolvability in water and excellent in anti-caking property and which include (a) particles containing an alkali agent and having an average particle size of from 150 to 1000 μm, and a layer of (b) clay mineral particles exhibiting a water impregnation capacity of 200% by mass or more and having an average particle size of from 1 to 200 μm, the layer being formed on a surface of the respective particles (a); and [2] a method for suppressing caking of the alkali agent-containing particles including the step of forming a layer of the clay mineral particles (b) on a surface of the respective particles (a).
US08455424B2 Detergents and cleaning agents containing proteases from Bacillus pumilus
Detergents and cleaning agents containing a protease having an amino acid sequence being at least 97.5% identical to the amino acid sequence given in SEQ ID NO. 3. The detergents and cleaning agents exhibit an excellent cleaning action on protease-sensitive soiling.
US08455423B2 Process of bleaching
An aqueous solution of a water soluble salt of a preformed transition metal catalyst together with hydrogen peroxide is disclosed. The composition is useful in bleaching a variety of substrates.
US08455422B2 Process for making a methyl glycine diacetic acid particle
A particle comprising an aminocarboxylic builder obtainable by a process comprising the steps of: a) providing a solution comprising the aminocarboxylic builder; b) optionally adding an acidifying agent; c) adding sulphate or citrate to the solution resulting from of step b) to form a mixture; and d) converting the mixture resulting from step c) into particles.
US08455420B2 Spin-on formulation and method for stripping an ion implanted photoresist
A spin-on formulation that is useful in stripping an ion implanted photoresist is provided that includes an aqueous solution of a water soluble polymer containing at least one acidic functional group, and at least one lanthanide metal-containing oxidant. The spin-on formulation is applied to an ion implanted photoresist and baked to form a modified photoresist. The modified photoresist is soluble in aqueous, acid or organic solvents. As such one of the aforementioned solvents can be used to completely strip the ion implanted photoresist as well as any photoresist residue that may be present. A rinse step can follow the stripping of the modified photoresist.
US08455414B2 Macromolecular amine-phenolic antioxidant compositions, process technology thereof, and uses thereof
This invention relates to novel macromolecular amine-phenolic compositions having oxidation inhibition characteristics that are exhibited when added to organic material normally susceptible to oxidative degradation in the presence of air or oxygen, such as petroleum products, synthetic polymers, and elastomeric substances.
US08455412B2 Acetic acid-capped estolide base oils and methods of making the same
Provided herein are compounds, including those of the Formula II in which n is an integer equal to or greater than 1; R2, is selected from hydrogen and optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched; and R3, and R4, independently for each occurrence, are selected from optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched. Also provided are compositions containing such compounds and methods of making both compounds and compositions thereof.
US08455411B2 Lubricant composition based on natural and renewable raw materials
The invention relates to a lubricant composition based on modified, natural and renewable raw materials, the viscosity of which can be adjusted according to the application. The invention relates more particularly to biodegradable lubricant compositions.
US08455410B2 Lubricating oil composition
A crankcase lubricating oil composition for an internal combustion engine comprising (A) an oil of lubricating viscosity in a major amount; and, (B) as an additive component in a minor amount one or more, oil-soluble imides derived from a hydrogenated Diels-Alder adduct of a maleic anhydride and a furan, where the imide group has the formula >NR, where R is an aliphatic hydrocarbyl group having 4 to 8 carbon atoms.
US08455401B2 Methods and devices for making arrays
The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array.
US08455398B2 Amide compounds, preparation methods and uses thereof
Amide compounds, preparation methods and uses thereof. The structure of the compounds is represented as the general formula (I), in which the definitions of substituents are illuminated as description. The present amide compounds have broad spectrum activity of killing pests and are effective on lepidopteran pests including ostrinia nubilalis, sugarcane borer, adoxophyes orana fischer von reslerstamm, apple fruit borer, grapholitha inopinata, lymantri dispar l., cnaphalocrocis medinalis, ostrinia furnacalis, helicoverpa assulta, grapholitha inopinata, plutella xylostella, spodoptera exigua, prodenia litura etc., especially for plutella xylostella, spodoptera exigua. The present amide compounds can obtain good effect at very low dosage. At the same time, some compounds have good fungicidal activity which can be used to prevent rice blast, phytophthora infestans, cucumber downy mildew or grey mold of vegetables.
US08455391B2 Exhaust gas purifying catalyst and manufacturing method of the same
An exhaust gas purifying catalyst (1) includes: a three-dimensional structural substrate (10) having a plurality of cells (11) partitioned by cell walls (12) having pores (13); and catalyst layers (20) formed in the three-dimensional structural substrate (10). The catalyst layers (20) have pore-cover portions (22) formed on surfaces (13a) of the pores (13) of the cell walls (12). In addition, the catalyst layers (20) of the pore-cover portions (22) have activated pores (22a) with a pore diameter of 0.1 micrometers to 10 micrometers. In the exhaust gas purifying catalyst (1), the obstruction of the vent holes (pores (13)) in the catalyst layers (20) can be controlled, and the pressure loss can be reduced.
US08455388B2 Attrition resistant mixed metal oxide ammoxidation catalysts
A catalytic composition useful for the conversion of an olefin selected from the group consisting of propylene, isobutylene or mixtures thereof, to acrylonitrile, methacrylonitrile, and mixtures thereof. The catalytic composition comprising a complex of metal oxides comprising bismuth, molybdenum, iron, cerium and other promoters, wherein the ratio of cerium to iron in the composition is greater than or equal to 0.8 and less than or equal to 5.
US08455384B2 Method for preparing fuel cell electrode catalyst and solid polymer fuel cell
According to the present invention, the catalyst performance of a chelate catalyst comprising a complex of a macrocyclic compound such as a porphyrin derivative is improved. Also, the following method is provided: a method for preparing a fuel cell electrode catalyst comprising a nitrogen-containing metal complex in which a metallic element is coordinated with a macrocyclic organic compound, such method comprising the steps of: adding tin oxalate to the nitrogen-containing metal complex; and baking a mixture of the nitrogen-containing metal complex and tin oxalate in an inert gas atmosphere, wherein elution of metal tin is carried out via acid treatment.
US08455383B2 Process for catalyst regeneration and extended use
A method of producing an alkylaromatic by the alkylation of an aromatic with an alkylating agent, such as producing ethylbenzene by an alkylation reaction of benzene, is disclosed. The method includes using an H-beta catalyst to minimize process upsets due to alkylation catalyst deactivation and the resulting catalyst regeneration or replacement. The H-beta catalyst can be used in a preliminary alkylation reactor that is located upstream of the primary alkylation reactor. The H-beta catalyst used in a preliminary alkylation reactor can lead to the reactivation of the catalyst in the primary alkylation reactor.
US08455381B2 Ceramic material composition, ceramic substrate, and nonreciprocal circuit device
A ceramic material composition advantageously used as a material for a ceramic substrate containing for example a resistor such as an isolator disposed therein.includes about 10 to 45 percent by weight of a BaO—TiO2—ReO3/2 ceramic composition, the ceramic composition being represented by xBaO-yTiO2-zReO3/2 (wherein x, y, and z each represent mole percent, 8≦x≦18, 52.5≦y≦65, and 20≦z≦40, and x+y+z=100; and Re represents a rare-earth element); about 5 to 40 percent by weight of alumina; and about 40 to 65 percent by weight of a borosilicate glass composition containing about 4 to 17.5 percent by weight of B2O3, about 28 to 50 percent by weight of SiO2, 0 to about 20 percent by weight of Al2O3, and about 36 to 50 percent by weight of MO (wherein MO represents at least one compound selected from CaO, MgO, SrO and BaO), wherein the total content of the BaO—TiO2—ReO3/2 ceramic composition and alumina is about 35 percent by weight or more.
US08455380B2 Self-levelling concrete
A powder including, in percentages by weight: (a) 94% to 99% of particles of at least one refractory material, the main constituent(s) of which are alumina and/or zirconia and/or silica; (b) 1% to 6% of a hydraulic cement; (c) 0 to 0.03% of organic fibers; (d) optionally, 0.075% to 1% of a surfactant; and (e) optionally, a setting accelerator, where the fraction of particles having a size below 40 μm being distributed, in percentages by weight relative to the weight of the powder, in the following manner: (1) fraction<0.5 μm: ≧4%, (2) fraction<2 μm: ≧5%, fraction<10 μm: ≧16%, and fraction<40 μm: 29-45%, where the proportion of zirconia in the fraction of particles having a size smaller than 10 μm, called “fines”, is between 35% and 75% by weight relative to the total weight of said fraction.
US08455375B2 Glass plate for display panels, process for producing it, and process for producing TFT panel
To provide a glass plate for display panels which has a low 82O3 content and a low compaction and which can be used as a glass substrate for large TFT panels.A glass plate for display panels, which comprises, as a glass matrix composition as represented by mass % based on oxide: SiO2 50.0 to 73.0, Al2O3 6.0 to 20.0, B2O3 0 to 2.0, MgO 4.2 to 9.0, CaO 0 to 6.0, SrO 0 to 2.0, BaO 0 to 2.0, MgO+CaO+SrO+BaO 6.5 to 11.3, Li2O 0 to 2.0, Na2O 2.0 to 18.0, K2O 0 to 13.0, and Li2O+Na2O+K2O 8.0 to 18.0, and has a heat shrinkage (C) of at most 20 ppm.
US08455372B2 Method for cleaning and passivating gallium arsenide surface autologous oxide and depositing AL203 dielectric
The present invention belongs to the technical field of semiconductor materials and specifically relates to a method for cleaning and passivizing gallium arsenide (GaAs) surface autologous oxide and depositing an Al2O3 dielectric. This method includes: use a new-type of sulfur passivant to react with the autologous oxide on the GaAs surface to clean it and generate a passive sulfide film to separate the GaAs from the outside environment, thus preventing the GaAs from oxidizing again; further cleaning the residuals such as autologous oxides and sulfides on the GaAs surface through the pretreatment reaction of the reaction source trimethyl aluminum (TMA) of the Al2O3 ALD with the GaAs surface, and then deposit high-quality Al2O3 dielectric through ALD as the gate dielectric which fully separates the GaAs from the outside environment. The present invention features a simple process and good effects, and can provide preconditions for manufacturing the GaAs devices.
US08455368B2 Methods and apparatus for assembling and operating electronic device manufacturing systems
A method for operating one or more electronic device manufacturing systems is provided, including the steps 1) performing a series of electronic device manufacturing process steps with a process tool, wherein the process tool produces effluent as a byproduct of performing the series of process steps; 2) abating the effluent with an abatement tool; 3) supplying an abatement resource to the abatement tool from a first abatement resource supply; 4) changing an abatement resource supply from the first abatement resource supply to a second abatement resource supply, wherein changing the abatement resource supply comprises: i) interrupting a flow of the abatement resource from the first abatement resource supply; and ii) beginning a flow of the abatement resource from the second abatement resource supply; and 5) continuing to perform the series of process steps with the process tool, while changing, and after changing, the abatement resource supply.
US08455366B1 Use of an organic planarizing mask for cutting a plurality of gate lines
An organic planarizing layer (OPL) is formed atop a semiconductor substrate which includes a plurality of gate lines thereon. Each gate line includes at least a high k gate dielectric and a metal gate. A patterned photoresist having at least one pattern formed therein is then positioned atop the OPL. The at least one pattern in the photoresist is perpendicular to each of the gate lines. The pattern is then transferred by etching into the OPL and portions of each of the underlying gate lines to provide a plurality of gate stacks each including at least a high k gate dielectric portion and a metal gate portion. The patterned photoresist and the remaining OPL layer are then removed utilizing a sequence of steps including first contacting with a first acid, second contacting with an aqueous cerium-containing solution, and third contacting with a second acid.
US08455345B2 Methods of forming gate structure and methods of manufacturing semiconductor device including the same
A method of forming agate structure having an improved electric characteristic is disclosed. A gate insulating layer is formed on a substrate and a metal layer is formed on the gate insulating layer. Then, an amorphous silicon layer is formed on the metal layer by a physical vapor deposition (PVD) process. An impurity doped polysilicon layer is formed on the amorphous silicon layer. Formation of an oxide layer at an interface between the amorphous silicon layer and the metal layer may be prevented.
US08455344B2 Method of manufacturing non-volatile memory device
A non-volatile memory device includes field insulating layer patterns on a substrate to define an active region of the substrate, upper portions of the field insulating layer patterns protruding above an upper surface of the substrate, a tunnel insulating layer on the active region, a charge trapping layer on the tunnel insulating layer, a blocking layer on the charge trapping layer, first insulating layers on upper surfaces of the field insulating layer patterns, and a word line structure on the blocking layer and first insulating layers.
US08455337B2 Crystallization apparatus, crystallization method, method of manufacturing thin film transistor and method of manufacturing organic light emitting display apparatus
Provided are a crystallization apparatus and method, which prevent cracks from being generated, a method of manufacturing a thin film transistor (TFT), and a method of manufacturing an organic light emitting display apparatus. The crystallization apparatus includes a chamber for receiving a substrate, a first flash lamp and a second flash lamp, which are disposed facing each other within the chamber, wherein amorphous silicon layers are disposed on a first surface of the substrate facing the first flash lamp and a second surface of the substrate facing the second flash lamp, respectively.
US08455336B2 Method for making epitaxial structure
A method for making an epitaxial structure is provided. The method includes the following steps. A substrate is provided. The substrate has an epitaxial growth surface for growing epitaxial layer. A carbon nanotube layer is placed on the epitaxial growth surface. A plurality of epitaxial crystal grains spaced from each other is epitaxially grown on the epitaxial growth surface. Also, the carbon nanotube layer can be further removed.
US08455333B2 Method for reuse of wafers for growth of vertically-aligned wire arrays
Reusing a Si wafer for the formation of wire arrays by transferring the wire arrays to a polymer matrix, reusing a patterned oxide for several array growths, and finally polishing and reoxidizing the wafer surface and reapplying the patterned oxide.
US08455327B2 Trench capacitor with spacer-less fabrication process
A trench capacitor and method of fabrication are disclosed. The SOI region is doped such that a selective isotropic etch used for trench widening does not cause appreciable pullback of the SOI region, and no spacers are needed in the upper portion of the trench.
US08455326B2 Method for fabricating a connection region in a semiconductor device
Disclosed herein is a fabrication method of a semiconductor device to order to increase an operation liability of the semiconductor device. A method for fabricating a semiconductor device comprises forming a buried-type wordline in an active region defined on a SOI substrate, forming a silicon connection region for connecting an upper silicon layer to a lower silicon layer between neighboring buried type wordlines, and recovering the upper silicon layer on the silicon connection region.
US08455324B2 Method of manufacturing a semiconductor device
A method of manufacturing a semiconductor device which includes forming a gate insulating film and a gate electrode over a semiconductor substrate, forming a first recess in the first semiconductor substrate on both sides of the gate electrode by dry etching, forming a second recess by removing a bottom and sidewalls of the first recess by wet etching, and forming a semiconductor layer in the second recess.
US08455322B2 Silicon germanium heterojunction bipolar transistor structure and method
Disclosed is an improved semiconductor structure (e.g., a silicon germanium (SiGe) hetero-junction bipolar transistor) having a narrow essentially interstitial-free SIC pedestal with minimal overlap of the extrinsic base. Also, disclosed is a method of forming the transistor which uses laser annealing, as opposed to rapid thermal annealing, of the SIC pedestal to produce both a narrow SIC pedestal and an essentially interstitial-free collector. Thus, the resulting SiGe HBT transistor can be produced with narrower base and collector space-charge regions than can be achieved with conventional technology.
US08455320B2 Inverted-trench grounded-source FET structure using conductive substrates, with highly doped substrates
This invention discloses an inverted field-effect-transistor (iT-FET) semiconductor device that includes a source disposed on a bottom and a drain disposed on a top of a semiconductor substrate. The semiconductor power device further comprises a trench-sidewall gate placed on sidewalls at a lower portion of a vertical trench surrounded by a body region encompassing a source region with a low resistivity body-source structure connected to a bottom source electrode and a drain link region disposed on top of said body regions thus constituting a drift region. The drift region is operated with a floating potential said iT-FET device achieving a self-termination.
US08455319B2 Vertical transistor for random-access memory and manufacturing method thereof
A manufacturing method for a vertical transistor of random-access memory, having the steps of: defining an active region on a semiconductor substrate; forming a shallow trench isolation structure outside of the active region; etching the active region and forming a gate dielectric layer and a positioning gate thereon, forming a word line perpendicular to the positioning gate; forming spacing layers on the outer surfaces of the word line; implanting ions to the formed structure in forming an n-type and a p-type region on opposite sides of the word line with the active region; forming an n-type and a p-type floating body respectively on the n-type and p-type region; forming a source line perpendicular to the word line and connecting to the n-type floating body; forming a bit line perpendicular to the source line and connecting to the p-type floating body. Hence, a vertical transistor with steady threshold voltage is achieved.
US08455313B1 Method for fabricating finFET with merged fins and vertical silicide
A method is provided for fabricating a finFET device. Fin structures are formed over a BOX layer. The fin structures include a semiconductor layer and extend in a first direction. A gate stack is formed on the BOX layer over the fin structures and extending in a second direction. The gate stack includes a high-K dielectric layer and a metal gate. Gate spacers are formed on sidewalls of the gate stack, and an epi layer is deposited to merge the fin structures. Ions are implanted to form source and drain regions, and dummy spacers are formed on sidewalls of the gate spacers. The dummy spacers are used as a mask to recess or completely remove an exposed portion of the epi layer. Silicidation forms silicide regions that abut the source and drain regions and each include a vertical portion located on the vertical sidewall of the source or drain region.
US08455311B2 Solid state klystron
A solid state Klystron structure is fabricated by forming a source contact and a drain contact to both ends of a conducting wire and by forming a bias gate and a signal gate on the conducting wire. The conducting wire may be at least one carbon nanotube or at least one semiconductor wire with long ballistic mean free paths. By applying a signal at a frequency that corresponds to an integer multiple of the transit time of the ballistic carriers between adjacent fingers of the signal gate, the carriers are bunched within the conducting wire, thus amplifying the current through the solid state Klystron at a frequency of the signal to the signal gate, thus achieving a power gain.
US08455309B2 Method for manufacturing a semiconductor device
A technology is capable of simplifying a process of manufacturing an asymmetric device in forming a Tunneling Field Effect Transistor (TFET) structure. A method for manufacturing a semiconductor device comprises forming a conductive pattern over a semiconductor substrate, implanting impurity ions with the conductive pattern as a mask to form a first junction region in the semiconductor substrate, forming a first insulating film planarized with the conductive pattern over the first junction region, etching the top of the conductive pattern to expose a sidewall of the first insulating film, forming a spacer at the sidewall of the first insulating film disposed over the conductive pattern, etching the conductive pattern with the spacer as an etching mask to form a gate pattern, and forming a second junction region in the semiconductor substrate with the gate pattern as a mask.
US08455307B2 FINFET integrated circuits and methods for their fabrication
FINFET ICs and methods for their fabrication are provided. In accordance with one embodiment a FINFET IC is fabricated by forming in a substrate a region doped with an impurity of a first doping type. The substrate region is etched to form a recess defining a fin having a height and sidewalls and the recess adjacent the fin is filled with an insulator having a thickness less than the height. Spacers are formed on the sidewalls and a portion of the insulator is etched to expose a portion of the sidewalls. The exposed portion of the sidewalls is doped with an impurity of the first doping type, the exposed sidewalls are oxidized, and the sidewall spacers are removed. A gate insulator and gate electrode are formed overlying the fin, and end portions of the fin are doped with an impurity of a second doping type to form source and drain regions.
US08455306B2 Methods of forming voltage limiting devices
Embodiments include methods for forming an electrostatic discharge (ESD) protection device coupled across input-output (I/O) and common terminals of a core circuit, where the ESD protection device includes first and second merged bipolar transistors. A base of the first transistor serves as collector of the second transistor and the base of the second transistor serves as collector of the first transistor, the bases having, respectively, first and second widths. A first resistance is coupled between an emitter and base of the first transistor and a second resistance is coupled between an emitter and base of the second transistor. ESD trigger voltage Vt1 and holding voltage Vh can be independently optimized by choosing appropriate base widths and resistances. By increasing Vh to approximately equal Vt1, the ESD protection is more robust, especially for applications with narrow design windows, for example, with operating voltage close to the degradation voltage.
US08455303B2 Semiconductor package with adhesive material pre-printed on the lead frame and chip, and its manufacturing method
This invention discloses a semiconductor package with adhesive material pre-printed on the lead frame and chip, and the manufacturing method. The adhesive material is applied onto the chip carrier and the pin of the lead frame and also on the front electrode of the semiconductor chip via pre-printing. The back of the semiconductor chip is adhered on the chip carrier, and the front electrode of the semiconductor chip and the pin are connected respectively with a metal connector. The size, shape and thickness of the adhesive material are applied according to different application requirements according to size and shapes of the contact zone of the semiconductor chip and the metal connector. Particularly, the adhesive zones are formed by pre-printing the adhesive material thus significantly enhance the quality and performance of semiconductor products, and improves the productivity.
US08455301B2 Method of fabricating stacked chips in a semiconductor package
A method of forming a semiconductor package includes attaching a semiconductor substrate on a support substrate, wherein the semiconductor substrate includes a plurality of first semiconductor chips and a chip cutting region that separates respective ones of the semiconductor chips. A first cutting groove is formed that has a first kerf width between first and second ones of the plurality of first semiconductor chips. A plurality of second semiconductor chips is attached to the plurality of first semiconductor chips. A molding layer is formed so as to fill the first cutting groove and a second cutting groove having a second kerf width that is less than the first kerf width is formed in the molding layer so as to form individual molding layers covering one of the plurality of first semiconductor chips and one of the plurality of second semiconductor chips.
US08455298B2 Method for forming self-aligned phase-change semiconductor diode memory
A method for fabricating a memory device includes depositing a phase-change and/or a resistive change material. The memory device is formed photolithographically using sixteen or fewer masks.
US08455293B2 Method for processing solar cell substrates
A method for processing solar cells comprising: providing a vertical furnace to receive an array of mutually spaced circular semiconductor wafers for integrated circuit processing; composing a process chamber loading configuration for solar cell substrates, wherein a size of the solar cell substrates that extends along a first surface to be processed is smaller than a corresponding size of the circular semiconductor wafers, such that multiple arrays of mutually spaced solar cell substrates can be accommodated in the process chamber, loading the solar cell substrates into the process chamber; subjecting the solar cell substrates to a process in the process chamber.
US08455291B2 Method of manufacturing solid state imaging device, solid state imaging device, and camera using solid state imaging device
A method of manufacturing a solid state imaging device having a photo-electric conversion portion array and a transfer electrode array, these arrays being provided in parallel to each other, upper surfaces and side wall surfaces of the transfer electrode array being covered with a light-shielding layer, and a transparent layer showing an oxidizing property at the time of film formation, the transparent layer being formed on the photo-electric conversion parts and the light-shielding layer.
US08455280B1 Method for manufacturing light emitting diodes
An exemplary method for manufacturing LEDs includes steps: providing a substrate and an epitaxial layer formed on the substrate; etching the epitaxial layer along a transverse direction thereof to divide the epitaxial layer into separated LED chips, and a groove defined between each two adjacent LED chips; providing insulating poles and inserting the insulating poles in the grooves; printing a solder paste layer on a top surface of each LED chip away from the substrate; reflow soldering the LED chips to make the solder paste layers mounted on the LED chips become solder balls; releasing the substrate from the LED chips; etching the insulating poles until the insulating poles are totally removed and the LED chips are separated from each other; and providing metallic plates and respectively soldering the metallic plates on the solder balls of the LED chips.
US08455277B2 Thin film transistor array panel and manufacturing method thereof
A thin film transistor array panel is provided, which includes a plurality of gate lines, a plurality of common electrodes, a gate insulating layer covering the gate lines and the common electrodes, a plurality of semiconductor layers formed on the gate insulating layer, a plurality of data lines including a plurality of source electrodes and formed on the semiconductor layer, a plurality of drain electrodes formed on the semiconductor layer, and a plurality of pixel electrodes overlapping the common electrodes and connected to the drain electrodes. Because the common electrodes are made of ITON, IZON, or a-ITON, or a double layer of ITO/ITON, IZO/IZON, or a-a-ITO/a-ITON, when H2 or SiH4 are injected to form a silicon nitride (SiNX) layer on the common electrodes, the opaque metal Sn or Zn is not produced on the surfaces of the common electrode.
US08455273B2 Method for producing crystalline nitride phosphors
This invention relates to a new method for the production of nitride-based phosphors, in particular, of phosphors containing rare earth elements. The phosphors can be used, for example, in light sources, especially in Light Emitting Devices (LEDs).
US08455272B2 Method for producing organic electroluminescence element and organic electroluminescence element
A method for producing an organic electroluminescence element, the method including subjecting an anode to a surface treatment using at least one non-oxidizing gas, and forming a p-doped hole-injection layer on a surface of the anode subjected to the surface treatment.
US08455271B2 Highly integrated wafer bonded MEMS devices with release-free membrane manufacture for high density print heads
A method of fabricating a MEMS inkjet type print head and the resulting device is disclosed. The method includes providing a driver component and separately providing an actuatable membrane component, the actuatable membrane component being formed in the absence of an acid etch removing a sacrificial layer. The separately provided actuatable membrane component is bonded to the driver component and a nozzle plate is attached to the actuatable membrane component subsequent to the bonding. Separately fabricating the components removes the need for hydrofluoric acid etch removal of a sacrificial layer previously required for forming the actuatable membrane with respect to the driver component.
US08455270B2 3D multiple die stacking
A process of forming three-dimensional (3D) die. A plurality of wafers are tested for die that pass (good die) or fail (bad die) predetermined test criteria. Two tested wafers are placed in proximity to each other. The wafers are aligned in such a manner so as to maximize the number of good die aligned between the two wafers. The two wafers are then bonded together and diced into individual stacks of bonded good die.
US08455269B2 Method for recovering an on-state forward voltage and, shrinking stacking faults in bipolar semiconductor devices, and the bipolar semiconductor devices
In a bipolar semiconductor device such that electrons and holes are recombined in a silicon carbide epitaxial film grown from the surface of a silicon carbide single crystal substrate at the time of on-state forward bias operation; an on-state forward voltage increased in a silicon carbide bipolar semiconductor device is recovered by shrinking the stacking fault area enlarged by on-state forward bias operation. In a method of this invention, the bipolar semiconductor device in which the stacking fault area enlarged and the on-state forward voltage has been increased by on-state forward bias operation, is heated at a temperature of higher than 350° C.
US08455268B2 Gate replacement with top oxide regrowth for the top oxide improvement
Methods of replacing/reforming a top oxide around a charge storage element of a memory cell and methods of improving quality of a top oxide around a charge storage element of a memory cell are provided. The method can involve removing a first poly over a first top oxide from the memory cell; removing the first top oxide from the memory cell; and forming a second top oxide around the charge storage element. The second top oxide can be formed by oxidizing a portion of the charge storage element or by forming a sacrificial layer over the charge storage element and oxidizing the sacrificial layer to a second top oxide.
US08455267B2 Magnetic tunnel junction device and fabrication
A magnetic tunnel junction (MTJ) device and fabrication method is disclosed. In a particular embodiment, a method is disclosed that includes forming a magnetic tunnel junction (MTJ) device on a structure that includes a bottom cap layer and a bottom metal-filled trench having a normal axis, the magnetic tunnel junction device including a bottom electrode, magnetic tunnel junction layers, a magnetic tunnel junction seal layer, a top electrode, and a logic cap layer, the magnetic tunnel junction device having an MTJ axis that is offset from the normal axis.
US08455265B2 Surface grafted conjugated polymers
A surface grafted conjugated polyelectrolyte (CPE) is formed by coupling a CPE by a coupling moiety to the surface of a substrate. The substrate can be of any shape and size, and for many uses of the surface grafted CPE, it is advantageous that the substrate is a nanoparticle or microparticle. Surface grafted CPEs are presented that use silica particles as the substrate, where a modified silane coupling agent connects the surface to the CPE by a series of covalent bonds. Two methods of preparing the surface grafted CPEs are presented. One method involves the inclusion of the surface being modified by the coupling agent and condensed with monomers that form the CPE in a grafted state to the substrate. A second method involves the formation of a CPE with terminal groups that are complimentary to functionality that has been placed on the surface of the substrate by reaction with a coupling agent. The surface grafted CPEs are also described for use as biosensors and biocides.
US08455263B2 Quantitative analyte assay device and method
The present invention relates to an assay device and a method for using such for the quantitative determination of an analyte, based on a test strip, which contains a porous test membrane allowing for capillary flow of the analyte and complexes of the analyte, a porous upstream membrane in fluid connection with the test membrane and a porous downstream membrane in fluid connection with the test membrane, wherein the test membrane contains a test site having immobilized thereon a ligand capable of reacting with the analyte and binding such to the test site, and two standard band sites having immobilized thereon known high and low concentrations of a calibrator agent capable of reacting with a label conjugate and binding such to the standard sites, wherein the upstream membrane has a site for the application of a sample to be analyzed, and has a site downstream from the sample application site for depositing label conjugates capable of reacting with the analyte and label conjugates capable of reacting with the immobilized calibrator agents in the standard bands to provide a known label response in the standards bands, and the downstream membrane is capable of absorbing said sample and providing the capillary flow for the sample through the upstream and test membrane.
US08455262B2 Method to avert an unlawfully intoxicated driver from operating a vehicle by passive measurement of an ethanol vapor concentration in air
A method to avert an unlawfully intoxicated driver from operating a vehicle is provided. The method utilizes a passive ethanol vapor sensor to measure ethanol vapor concentration in air from a vehicle cabin and imposes a safety response when the passive ethanol vapor sensor detects that a sample of vehicle cabin air indicates that a vehicle occupant exceeds the legal blood alcohol concentration (BAC) for a motor vehicle driver. The ethanol vapor sensor may have a passive measurement mode and an active breathalyzer mode. Ethanol vapor in a vehicle cabin may be passively measured and if a predetermined ethanol level is measured, a countermeasure is invoked to improve safety. An active breathalyzer may be used as a countermeasure. The active breathalyzer can be imposed for a number of vehicle trips or for a predetermined time period.
US08455259B2 Thyroglobulin quantitation by mass spectrometry
Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.
US08455258B2 Apparatus and methods for conducting assays and high throughput screening
The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and high throughput screening. Microfluidic devices of the present invention include elastomeric components and comprise a main flow channel; a plurality of branch flow channels; a plurality of control channels; and a plurality of valves. Preferably, each of the valves comprises one of the control channels and an elastomeric segment that is deflectable into or retractable from the main or branch flow channel upon which the valve operates in response to an actuation force applied to the control channel.
US08455253B2 Differentiation of MUTZ-3 cells to produce effective dendritic cells
Disclosed is a method for the production and use of CD124+ and CD116+ cell lines in the production of effective dendritic cells (DC) with the aid of stimulatory molecules.
US08455252B2 Materials and methods for sensitizing multidrug resistant cells
Disclosed herein are materials and methods for sensitizing multidrug resistant cancer cells that express ABCG2 and related proteins members of a family of ATP-binding transporter superfamily that mediate drug efflux found in some types of multidrug resistant cancer cells. A series of compounds, including (N-(4-chlorophenyl)-2-[(6-{[4,6-di(4-morpholinyl)-1,3,5-tri-azin-2-yl]amino}-1,3-benzothiazol-2-yl)sulfanyl]acetamide), specifically inhibits ABCG2 and can be used to boost the bio-avail-ability of one or more effective cancer killing drugs, making it possible to use certain widely used chemotherapeutic reagent to treat multidrug resistance cancers. Using these compounds in combination with chemotherapeutic drugs that are substrates for ABCG2 and related proteins may also find utility in treating cancer cells that are not currently identified as multi-drug resistant. Additionally, these compounds appear to accelerate the intercellular degradation of ABCG2 and related proteins. They are not toxic to animals at levels at which they effect the activity of ABCG2 expressed in multi-drug resistant cancer lines.
US08455251B2 Method for isolating and culturing adult stem cells derived from human amniotic epithelium
The present invention relates to a method for isolating and culturing adult stem cells derived from human amniotic membrane in high yield, and more particularly to a method for obtaining a large amount of adult stem cells, the method comprising obtaining amniotic epithelial cells from human amniotic tissue in high yield by treatment with dithiothreitol (DTT) and a low concentration of trypsin and culturing the amniotic epithelial cells in a medium containing a Rho-associated kinase inhibitor. The human amniotic epithelial cell-derived stem cells are easily extracted compared to existing therapeutic stem cells such as umbilical cord blood stem cells and bone marrow stem cells, the yield and proliferation thereof are significantly increased by DTT treatment, the addition of the ROCK inhibitor or the replacement of medium. Thus, the method can be used to efficiently prepare adult stem cells.
US08455247B2 Cells useful for immuno-based botulinum toxin serotype A activity assays
The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
US08455246B2 Serum-free mammalian cell culture medium, and uses thereof
The present invention provides a cell culture medium formulation that supports the in vitro cultivation, particularly in suspension, of mammalian cells, particularly epithelial cells and fibroblast cells, and methods for cultivating mammalian cells in suspension in vitro using these media. The media comprise a basal medium and a polyanionic or polyanionic compound, preferably a polysulfonated or polysulfated compound, and more preferably dextran sulfate. The present invention also provides chemically defined, protein-free eukaryotic cell culture media comprising an iron chelate and zinc, which is capable of supporting the growth (and particularly the high-density growth of mammalian cells) in suspension culture, increasing the level of expression of recombinant protein in cultured cells, and/or increasing virus production in cultured cells.
US08455240B2 Use of thermophilic sulphate-reducing archaea for the implementation of a process for the degradation of hydrocarbons
The aim of the invention is to use sulphate-reducing thermophilic archaeobacteria for carrying out a method for degrading linear or branched, saturated or unsaturated, when necessary sulphur, aromatic hydrocarbons under anaerobic conditions.
US08455238B2 Microorganisms and methods for treating poultry
An isolated Bacillus strain LSSAO1 is provided. When fed to a bird, this and other Bacillus strains described herein provide benefits to the birds. For example, administration of the one or more Bacillus strain can increase low G+C, gram positive bacteria in the gastrointestinal flora of the bird. These type of bacteria are increased by antibiotics and include beneficial Clostridium. Administration of the one or more Bacillus strain can also inhibit pathogen in the bird, such as E. coli, Salmonella, and Clostridium. These benefits can enhance feed conversion in poultry. Useful combinations of Bacillus strains and methods of using one or more Bacillus strain are also provided.
US08455237B2 Escherichia coli strain with phosphoenolpyruvate carboxylase promoter replaced with cysteine synthase promoter and method of enhanced production of L-threonine using the same
An L-threonine-producing Escherichia coli in which a promoter of a phosphoenolpyruvate carboxylase (ppc) gene on the chromosome is substituted with a promoter of a cysteine synthase (cysK) gene and a method of producing L-threonine by using the same are disclosed. The recombinant Escherichia coli may produce L-threonine in a high yield, and thus may be widely used in medical, pharmaceutical, and feed industries, particularly for an animal feed.
US08455234B2 Multiple mutation variants of serine protease
The present invention provides novel Micrococcineae spp serine proteases having multiple substitutions. In particular, the present invention provides serine proteases having multiple substitutions, DNA encoding these proteases, vectors comprising the DNA encoding the proteases, host cells transformed with the vector DNA, and enzymes produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising these serine protease variants. In particularly preferred embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These variant proteases also find use in numerous applications.
US08455232B2 Overexpression of phytase genes in yeast systems
The present invention relates to a method of producing a heterologous protein or polypeptide having phytase activity in a yeast system. The invention also provides proteins having phytase activity which have increased thermostability. Yeast strains which produce a heterologous phytase and the vectors used to produce the phytase are also provided.
US08455227B2 Detection of HIV-1 infection
This invention provides methods for to the use of the difference in phosphodiester (PDE)/phosphomonoester (PME) ratio in biological fluids, as an analytical criterion to image both the presence and degree of viral infection in-vivo.
US08455224B2 Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria
A high flux of metabolites from pyruvate to 2,3-butanediol in Lactobacillus plantarum was achieved through genetic engineering. Substantial elimination of lactate dehydrogenase activity in the presence of heterologously expressed butanediol dehydrogenase activity led to 2,3 butanediol production that was at least 49% of the total of major pyruvate-derived products.
US08455223B2 Dehydrogenases, the derivatives thereof, and method for the production of optically active alkanols
The present invention relates to proteins having an enzymatic activity of reducing substituted alkanones such as 3-methylamino-1-(2-thienyl)-propan-1-one. The invention furthermore relates to nucleic acids coding for said proteins, nucleic acid constructs, vectors, genetically modified microorganisms and to methods for preparing optically active substituted alkanols, such as, for example, (S)-3-methylamino-1-(2-thienyl)-(S)-propanol.
US08455219B2 Mammalian expression vectors and uses thereof
The present invention features nucleic acids for recombinant protein expression in mammalian cell culture. The episomal vectors of the invention promote high protein production in mammalian cells expressing the SV40 T Ag or Epstein-Barr virus nuclear antigen (e.g., COS7 or HEK293-6E cells). The methods and systems are useful, for example, in pharmaceutical drug development and cloning, especially for the production of antibodies.
US08455218B2 Methods for G-CSF production in a Pseudomonas host cell
The present invention relates to the field of recombinant protein production in bacterial hosts. It further relates to expression of soluble, active recombinant protein by using secretion signals to direct the protein to the periplasmic space of a bacterial cell. In particular, the present invention relates to a production process for obtaining soluble hG-CSF protein from a bacterial host.
US08455217B2 Nucleic acids encoding IL-17 homologous receptor-like polypeptides and therapeutic uses thereof
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
US08455214B2 Methods for determining chemotherapeutic agents targeting alpha-glucan pathways and uses thereof
The present invention provides methods for determining a putative antibacterial, the methods comprising determining whether the putative antibacterial inhibits GlgE or Rv3032. The present invention also provides the antibacterial, the pharmaceutical composition and the method of making the antibacterial as well as a method of treating a subject infected with a bacterial comprising administration of the antibacterial.
US08455213B2 Cells useful for immuno-based botulinum toxin serotype A activity assays
The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
US08455212B2 Assays for human NT-pro B-type natriuretic peptide, human pro B-type natriuretic peptide and human B-type natriuretic peptide
The present disclosure relates to assays for detecting and/or quantifying the amount of human NT-pro B-type natriuretic peptide, human pro B-type natriuretic peptide and human B-type natriuretic peptide in a test sample.
US08455208B2 Biomarkers for follicular thyroid carcinoma and methods of use
The present invention provides protein biomarkers for determining whether a thyroid nodule is malignant or benign and methods for using the same.
US08455204B2 Brown adipocyte progenitors in human skeletal muscle and methods for identifying differentiation agents therefor
Brown adipose tissue (“BAT”) progenitor cells and methods for identifying BAT progenitor cells in a population of cells are provided. Methods are also provided for inducing differentiation of BAT progenitor cells into differentiated brown adipocytes, inducing expression or increased activity levels of BAT uncoupling protein-1 (“UCP1”), and for identifying agents capable of inducing differentiation of BAT progenitor cells into brown adipocytes and/or inducing expression or increased activity levels of UCP1. Differentiated brown adipocytes and agents and methods for inducing differentiation of BAT progenitor cells can be used for treatment of, or the making of medicaments for the treatment of, metabolic diseases or conditions in a patient such as obesity, overweight, impaired glucose tolerance, insulin-resistance, type 2 diabetes, dyslipidemia, hypertension, cardiovascular diseases, metabolic syndrome, and the like. Differentiated brown adipocytes and agents and methods for inducing differentiation of BAT progenitor cells can be used for prevention of hypothermia.
US08455203B2 Immuno-based retargeted endopeptidase activity assays
The present specification discloses SNAP-25 immune response inducing compositions, methods of making α-SNAP-25 antibodies that selectively binds to an epitope comprising a SNAP-25 having a carboxyl-terminus at the P1 residue of the BoNT/A cleavage site scissile bond, α-SNAP-25 antibodies that selectively bind to an epitope comprising a SNAP-25 having a carboxyl-terminus at the P1 residue of the BoNT/A cleavage site scissile bond, methods of detecting retargeted endopeptidase activity, and methods of detecting neutralizing α-re-targeted endopeptidase antibodies.
US08455202B2 Affinity selector based recognition and quantification system and method for multiple analytes in a single analysis
A multi-dimensional method for simultaneously analyzing multiple analytes within a sample solution, comprising adding affinity selectors to a sample solution containing analytes to be measured, the affinity selectors having an affinity for one or more of the analytes within the sample solution; allowing immune complexes to form between the affinity selectors and the analytes; partially or totally resolving the formed immune complexes from non-analyte substances within the sample solution; dissociating the resolved immune complexes; separating the analytes and the affinity selectors of the dissociated immune complexes from one another by capturing the analytes through a surface adsorption process; transferring the captured analytes to a detection means; and resolving the analytes with the detection means in accordance with their mass-to-charge ratios.
US08455200B2 Measurement of PKA for cancer detection
The present invention relates to a method of detecting the presence of cancer by measuring the level of enzyme activity and autoantibodies in the blood of an individual. In particular the present invention relates to methods for measurement of activated cAMP-dependent protein kinase A (PKA) activity and antibodies to PKA, a kit for activated PKA activity measurement, and the use of the measured levels of these analytes for determining the presence of cancer.
US08455199B2 MicroRNA expression in human peripheral blood microvesicles and uses thereof
The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of disorders by examining samples containing microvesicles and miRs therein.
US08455198B2 Soybean plant and seed corresponding to transgenic event MON87701 and methods for detection thereof
The present invention provides a transgenic soybean event MON87701, and cells, seeds, and plants comprising DNA diagnostic for the soybean event. The invention also provides compositions comprising nucleotide sequences that are diagnostic for said soybean event in a biological sample, probes and primers for use in detecting nucleotide sequences that are diagnostic for the presence of said soybean event in a biological sample, and methods for detecting the presence of said soybean event nucleotide sequences in a biological sample. The invention further provides methods of growing the seeds of such soybean event into soybean plants, and methods of breeding to produce soybean plants comprising DNA diagnostic for the soybean event.
US08455193B2 Compositions and methods for nucleic acid sequencing
Compositions and methods for nucleic acid sequencing include template constructs that comprise double stranded portions in a partially or completely contiguous constructs, to provide for redundant sequence determination through one or both of sequencing sense and antisense strands, and iteratively sequencing the entire construct multiple times. Additional sequence components are also optionally included within such template constructs. Methods are also provided for the use and preparation of these constructs as well as sequencing compositions for their application.
US08455184B2 Differential multiplexing with pattern recognition
This novel form of multiplexing allows the user to probe for multiple targets and simultaneously identify a specific target. An example of solutions provided here comprises: providing one or more assay mixes for a number of targets (the number of assay mixes is less than the number of targets); providing a number of reference patterns (each of the reference patterns is associated with one of the targets); contacting each of a number of aliquots with one of the assay mixes; generating a result pattern, based on positive or negative results; and selecting the reference pattern most similar to the result pattern, to thereby detect the target. Differential multiplexing with pattern recognition may involve molecular or immunological techniques to identify one of many indicators of drug use, illness, disease, or medical condition.
US08455180B2 Gate CD control using local design on both sides of neighboring dummy gate level features
A method of forming an IC including MOS transistors includes using a gate mask to form a first active gate feature having a line width W1 over an active area and a neighboring dummy feature having a line width 0.8W1 to 1.3W1. The neighboring dummy feature has a first side adjacent to the first active gate feature, and a nearest gate level feature on a second side opposite the first side. The neighboring dummy feature defines a gate pitch based on a distance to the first active gate feature or the neighboring dummy feature maintains a gate pitch in a gate array including the first active gate feature. The spacing between the neighboring dummy feature and the nearest gate level feature (i) maintains the gate pitch or (ii) provides a SRAF enabling distance that is ≧2 times the gate pitch and the gate mask includes a SRAF over the SRAF distance.
US08455175B2 Photosensitive composition
Photoresist compositions and methods suitable for depositing a thick photoresist layer in a single coating application are provided. Such photoresist layers are particularly suitable for use in chip scale packaging, for example, in the formation of metal bumps.
US08455167B2 Toner, binary developer, and image forming method
It is an object of the present invention to provide a toner having the transfer efficiency and the cleanability in combination, exhibiting excellent stress resistance, and ensuring the low-temperature fixing.A toner characterized in that the average circularity of the above-described toner is 0.960 or more, and 0.985 or less, where the average circularity is analyzed by dividing particles having a circle equivalent diameter of 1.98 μm or more, and 200.00 μm or less, the number A of toners having a circularity of 0.990 or more, and 1.000 or less is 25.0 percent by the number or less, and the percentage of the number of particles B having a circle equivalent diameter of 0.50 μm or more, and 1.98 μm or less relative to the total particles of 0.50 μm or more, and 200.00 μm or less is 10.0 percent by the number or less.
US08455166B2 UV curable toner with improved scratch resistance
A radiation curable toner is described having at least a radiation curable binder (e.g. a UV curable polymer), a photoinitiator, and a wax; wherein the wax is present in a concentration ranging from 0.3 to 3% by weight. The ratio of scratch resistance before curing is preferably at least 2. The toner may be used in a developer, e.g. a two-component developer, for printing or copying.
US08455165B2 Cyclic-treated metal oxide
This invention provides metal oxide particles surface-treated with a cyclic silazane and a hydrophobicity-imparting agent, methods of making such, and toner compositions comprising the same.
US08455162B2 Alignment marks for multi-exposure lithography
A plurality of reticles for printing structures in the same lithography level includes an alignment structure pattern within a same relative location in each reticle. Each set of process segmentations in a grating has a reticle segmentation pitch, which is common across all gratings in the plurality of reticles. Within each pair of alignment structure patterns that occupy the same relative location in any two of the plurality of reticles, the process segmentations in one reticle are shifted relative to the process segmentations in the other reticle by a fraction of a reticle segmentation pitch. After printing all patterns in the plurality of reticles, a composite printed process segmentation structure on the substrate includes printed segmentation structures that are spaced by 1/n times the printed segmentation pitch. The pattern for the next level can be aligned to the composite printed process segmentation structure in a single alignment operation.
US08455160B2 Color filter of liquid crystal on silicon display device
A color filter of a liquid crystal on silicon (LCOS) display device is disclosed, including a substrate including a plurality of pixel regions wherein each pixel region includes a first color dot, a second color dot and a third color dot; and a first color resist, a second color resist and a third color resist disposed in the first color dot, the second color dot and the third color dot on the substrate, wherein each of the first color resist, the second color resist and the third color resist includes at least one opening.
US08455157B1 Methods for improving performance of holographic glasses
The improvement of the performance of holographic glasses with recorded holograms as measured by a figure of merit of the holographic glasses is disclosed. The improvement in the figure of merit of the holographic glasses is obtained at least in part with the addition of arsenic in the formation of the holographic glasses. The presence of arsenic increases the figure of merit as measured at a wavelength of interest of a holographic glass with a recorded hologram as compared to a holographic glass with a recorded hologram that does not contain arsenic.
US08455154B2 Thermal shock-tolerant solid oxide fuel cell stack
A solid oxide fuel cell (SOFC) includes a plurality of subassemblies. Each subassembly includes at least one subcell of a first electrode, a second electrode and an electrolyte between the first and second electrodes. A first bonding layer is at the second electrode and an interconnect layer is at the first bonding layer distal to the electrolyte. A second bonding layer that is compositionally distinct from the first bonding layer is at the interconnect layer, whereby the interconnect partitions the first and second bonding layers. A method of fabricating a fuel cell assembly includes co-firing at least two subassemblies using a third bonding layer that is microstructurally or compositionally distinct from the second bonding layer.
US08455153B2 Reduction-oxidation-tolerant electrodes for solid oxide fuel cells
An anode component of a solid oxide fuel cell is formed by combining a relatively coarse yttria-stabilized-zirconium (YSZ) powder, that is substantially composed of elongated particles, with a relatively fine NiO/YSZ or NiO powder of reduced particle size, whereby, upon sintering the combined powders, the coarse YSZ powder forms a microstructural cage of open porosity wherein the fine powder is distributed through the open porosity of the cage. A method of forming a cathode component includes combining a coarse YSZ powder, that is substantially composed of elongated particles, with a fine lanthanum strontium manganite powder of reduced particle size, whereby, upon sintering the combined powders, the coarse YSZ powder forms a microstructural cage of open porosity, wherein the fine powder is distributed through the open porosity of the cage.
US08455152B2 Integrated PEM fuel cell
An integrated PEM fuel cell includes bipolar plate assemblies that utilize fiber groups that extend from the surfaces of gas impermeable plates to terminate in uncoated tips facing adjacent tips to form anodes and cathodes of an MEA assembly. The catalyst support and catalyst can be applied to the tips as beads or thin layers and joined with a membrane. The assembly can use a unified seal and include collector plates at the ends of the stacks, using similar fiber construction.
US08455147B2 Hood interlock apparatus of industrial vehicle
A limit switch for detecting opening/closing of a hood is connected to a controller. A power supply relay is also connected to the controller. A switching contact of the relay is located on power supply line for supplying power supply from a fuel cell. When the hood is closed, the limit switch is on and the controller maintains the switching contact in a closed state so that power supply from the fuel cell to various power-consuming components is allowed. On the other hand, when the hood is opened, the limit switch is turned off. In response to this, the controller opens the switching contact so that the power supply from the fuel cell to the various power-consuming components is shut off.
US08455145B2 Photoelectrochemical method of separating water into hydrogen and oxygen, using melanins or the analogues, precursors or derivatives thereof as the central electrolysing element
The invention essentially consists in the use of melanins, melanin precursors or melanin derivatives, melanin variants, melanin analogues, natural or synthetic, pure or mixed with organic or inorganic compounds, metals, ions, drugs; as water electrolyzing material, using as sole or main source of energy, natural or synthetic light, coherent or not; in the systems of hydrogen production from water, known as photoelectrochemical systems. These systems integrate as semiconductor material and a water electrolyzer inside a monolithic design, to produce hydrogen directly from water, using light (between 200 to 900 nm) as the main or sole source of energy. At least to basic criteria had to be met: one was that the system or light absorbing compound should generate enough energy to start, lead and complete the photoelectrolysis reaction, being economical, stable and lasting in a water system, requirements met by melanins, representing thus an important and critical advance to solve the central problem of photoelectrochemical designs. The procedure can be applied to generate hydrogen, oxygen and high energy electrons, or the opposite sense, i.e., synthesizing water from the union of hydrogen and oxygen, generating electricity; it can be coupled to other processes, generating a multiplication effect; it can also be used for reduction of carbon dioxide, nitrates and sulphates or others.
US08455142B2 Non-aqueous electrolyte and non-aqueous electrolyte secondary battery using the same
A non-aqueous electrolyte can suppress decomposition of a solvent, improve the cycle life of a secondary battery, suppress the rise of resistance of a secondary battery and improve the capacity maintenance ratio of a secondary battery. A non-aqueous electrolyte secondary battery formed by using such a non-aqueous electrolyte includes a non-aqueous electrolyte containing an aprotic solvent and a disulfonic acid ester as expressed by chemical formula 1 shown below, a positive electrode and a negative electrode:
US08455139B2 Method for making lithium battery cathode composite material of lithium iron phosphate/lithium vanadium phosphate composite
A method for making a lithium battery cathode composite is provided. First, a plurality of lithium vanadium phosphate particles is provided. A lithium iron phosphate layer is then formed on an outer surface of each of the lithium vanadium phosphate particle by coating a lithium iron phosphate precursor slurry, thereby forming the lithium battery cathode composite.
US08455134B2 Secondary battery with insulating film between current collectors and a case
A secondary battery including an electrode assembly, the electrode assembly including a separator between a positive electrode and a negative electrode; current collectors, the current collectors being electrically connected to the positive electrode and the negative electrode, respectively; a case, the case accommodating the electrode assembly and the current collectors; a cap plate, the cap plate coupled to an opening in the case; and an insulating film between the current collectors and the case, the insulating film including a recess corresponding to a shape of at least one of the current collectors and the electrode assembly to offset a vibration of the current collectors with respect to the case.
US08455133B2 Battery pack
Disclosed herein is a multi-cell battery pack having optimal temperature distribution throughout the battery pack and optimal air flow through the battery pack. Disclosed herein is a battery pack which provides optimal temperature distribution throughout the battery pack, wherein maximum cell temperature (Tmax) and temperature differential amongst all cells in the battery pack (ΔTcell) are optimized for efficient thermal management providing safety, improved performance and extended life of the battery pack and electrochemical cells. Also disclosed herein is a battery pack which provides optimal flow through the battery pack and minimal pressure drop (ΔP) throughout the battery pack.
US08455131B2 Cathodes and reservoirs for aqueous lithium/air battery cells
Li/air battery cells are configurable to achieve very high energy density. The cells include a protected a lithium metal or alloy anode and an aqueous catholyte in a cathode compartment. In addition to the aqueous catholyte, components of the cathode compartment include an air cathode (e.g., oxygen electrode) and a variety of other possible elements.
US08455127B2 Battery cover latching assembly and portable electronic device utilizing same
A portable electronic device includes a housing defining, an operating module, and a battery cover. The housing defines a receiving hole and a connector hole. The operating module includes an operating element, and an elastic element. An operating block projects from the operating element and is slidably received in the receiving hole. The elastic element is elastically positioned between the housing and the operating element. The battery cover can be pivotably attached to the housing and latches with the operating element.
US08455126B2 Battery positioning device
A battery positioning device for fixing a battery includes a base defining a receiving groove to receive the battery, a first elastic member fixed in the receiving groove to resist a positive electrode of the battery. The first elastic member includes a main body, a fixing portion fixed to the base, and an operating portion. The main body includes a hook thereon. The hook includes a resisting portion to resist the positive electrode of the battery and a hooking portion hooking the positive electrode. The fixing portion and the operating portion extend from opposite ends of the main body, respectively. The operating portion is capable of moving away from the battery, thus deforming the first elastic member to elevate the battery by the hooking portion.
US08455125B2 Fixing mechanism
A fixing mechanism includes a battery sleeve, a resilient member and a battery cover. The battery sleeve defines an open end to receive a battery. The battery sleeve includes a latching portion formed in an inner surface thereof adjacent to the open end. The resilient member is fixed to the inner side surface of battery sleeve. The battery cover includes a guide portion defined in an outer surface thereof, and a latching portion connecting with the guide portion. The battery cover is rotatably engaged with the battery sleeve via the open end. The latching protrusion slides along the guide portion until the latching protrusion is locked in the latching portion, and the resilient member presses the battery to resist the battery cover.
US08455120B2 Secondary battery
The present invention relates to a secondary battery. The present invention is aimed to provide a secondary battery having a thin upper case formed of a metal. The secondary battery includes a bare cell; a protection circuit module having a circuit board; an upper case formed of a metal and having a cover plate for covering the circuit board of the protection circuit module; and a case-insulating layer formed on an external surface of the cover plate of the upper case.
US08455119B1 Disk having an underlayer that includes a plurality of nonmagnetic layers interleaved with magnetic layers
A magnetic disk includes a substrate, a soft magnetic underlayer disposed over the substrate, and a media layer disposed over the underlayer. The underlayer includes a plurality of magnetic layers each containing FeCoN having an atomic concentration of iron that is greater than an atomic concentration of cobalt, and has an atomic concentration of nitrogen that is less than the atomic concentration of cobalt. The atomic concentration of nitrogen is less than eight percent. The underlayer includes a plurality of nonmagnetic layers that are interleaved with the magnetic layers. Each of the nonmagnetic layers has a thickness that is less than one-tenth that of an adjoining layer of the magnetic layers. The media layer contains a magnetically hard material having an easy axis of magnetization oriented substantially perpendicular to both the media layer and the underlayer.
US08455118B2 Composite soft underlayer including negative anisotropy material
An apparatus may include a composite soft underlayer and a perpendicular magnetic recording layer overlying the composite soft underlayer. The composite soft underlayer may include a growth template layer, a negative magnetic anisotropy layer overlying the growth template layer, and a magnetically soft layer overlying the negative magnetic anisotropy layer. In some embodiments, the negative magnetic anisotropy layer includes a plurality of grains, and substantially all the grains have negative magnetic anisotropy along an axis substantially perpendicular to a major plane of the composite soft underlayer. In some embodiments, the negative magnetic anisotropy layer includes a thickness of less than or equal to about 3 nm.
US08455117B2 Bit-patterned stack with antiferromagnetic shell
A method of producing bit-patterned media is provided whereby a shell structure is added on a bit-patterned media dot. The shell may be an antiferromagnetic material that will help stabilize the magnetization configuration at the remanent state due to exchange coupling between the dot and its shell. Therefore, this approach also improves the thermal stability of the media dot and helps each individual media dot maintain a single domain state.
US08455114B2 Light emitting element and light emitting device using the same
An object of the present invention is to provide a light emitting element having slight increase in driving voltage with accumulation of light emitting time. Another object of the invention is to provide a light emitting element having slight increase in resistance with increase in film thickness. In an aspect of the invention, a light emitting element includes a first layer, a second layer and a third layer between mutually-facing first and second electrodes. The first layer is provided to be closer to the first electrode than the second layer. The third layer is provided to be closer to the second electrode than the second layer. The first layer contains a bipolar substance and a substance exhibiting an electron accepting ability with respect to the bipolar substance. The second layer contains a bipolar substance and a substance exhibiting an electron donating ability with respect to the bipolar substance. The third layer contains a light emitting substance.
US08455112B2 Organometallic complexes which emit in the red to green spectral region and their use in OLEDs
Organometallic complexes which bear at least one ligand which has a unit having a triplet energy of at least 22 000 cm−1, a process for preparing the organometallic complexes, a mixture comprising at least one of these organometallic complexes, the use of the organometallic complexes or of the mixture in organic light-emitting diodes, the organometallic complexes preferably being used as emitter materials, and specific nitrogen- or phosphorus-substituted triphenylene derivatives and a process for their preparation, the organometallic complex including a monoanionic bidentate ligand of formula (IIa)
US08455110B2 Aluminium brazing sheet material
A brazing sheet material for CAB brazing without applying flux. The brazing sheet material including an aluminum core alloy layer provided with a first brazing clad layer material on one or both sides of the aluminum core layer and at least one second brazing clad layer material positioned between the aluminum core alloy layer and the first braze clad layer material. The second brazing clad layer material is an Al—Si alloy brazing material having 5% to 20% Si and 0.01% to 3% Mg, and the first brazing clad layer material is an Al—Si alloy brazing material having 2% to 14% Si and less than 0.4% Mg. Also disclosed is a brazed assembly manufactured in a brazing operation.
US08455107B2 Method of treating cellulosic materials with hydrophobins
By treatment with hydrophobins, cellulosic materials such as paper, cardboard, cotton or, especially, wood-based materials, such as solid wood, glued wood products or particle board, can be effectively protected against absorption of and attack by water and/or moisture.
US08455097B2 Coating liquid for covering glass fiber and rubber-reinforcing glass fiber using same
There is disclosed a glass-fiber coating liquid for forming a coating layer on a glass fiber cord, prepared in the form of an emulsion by dispersing a phenol resin, a vinylpyridine-stylene-butadiene copolymer (B) and a chlorosulfonated polyethylene (C) into water to form a coating layer on a glass fiber cord, wherein the phenol resin is a monohydroxybenzene-formaldehyde resin (A) obtained by reaction of monohydroxybenzene (D) and formaldehyde (E).
US08455095B2 Article and method for manufacturing same
An article includes a substrate; and a color layer deposited on the substrate, wherein the color layer has an L* value between about 28 to about 32, an a* value between about −1 to about 1, and a b* value between about −1 to about 1 in the CIE L*a*b* color space.
US08455094B2 Medical device having surface lubricity in wet state
A medical device wherein a surface lubricating layer and one of various polymer bases are fixed with each other firmly by a relatively simple technique. The medical device permanently exhibits excellent surface lubricity when in use. The medical device has a lubricating surface when wet, and includes a base layer at least the surface of which is composed of a polymer material, a compound (thiol compound) which is supported on at least a part of the base layer and has a plurality of thiol groups in each molecule, and a surface lubricating layer which covers the thiol compound and is composed of a hydrophilic polymer that has a reactive functional group.
US08455090B2 Prepegs and molded bodies produced thereof at low temperature
The invention relates to prepregs and composite components (molding) produced therefrom at a low temperature, obtainable by using powdery highly reactive polyurethane compositions containing uretdione groups, with specific catalysts.
US08455089B2 Preform for molding fiber-reinforced resin beam
A preform for the molding of a fiber-reinforced resin beam includes a reinforcing-fiber beam which has been formed from a reinforcing-fiber base made up of many reinforcing fibers and has a cross-sectional shape with at least one linear part and at least one curved part connected to the linear part; and a release sheet bonded and united through an adhesive resin to at least part of a surface of the reinforcing-fiber base along the lengthwise direction for the base. A process for producing a preform includes shaping a continuous flat reinforcing-fiber base having a release sheet bonded and united to a surface thereof so that the cross-sectional shape of the base has a curved part to thereby produce a preshaped object; and bonding and uniting the preshaped object to another preshaped object.
US08455085B2 Metal/composite joint with selective interlaminar reinforcement
A metal/composite joint. An illustrative embodiment of the metal/composite joint includes a metallic component, a composite component provided in engagement with the metallic component, an engagement region defining contact between the metallic component and the composite component and a plurality of attachment projections joining the metallic component and the composite component. The attachment projections may be non-uniformly distributed along the engagement region. A method of joining a metallic component and a composite component is also included.
US08455083B2 Pressure-sensitive adhesive sheet
A pressure-sensitive adhesive sheet includes a base material and a pressure-sensitive adhesive layer and is formed therein with a plurality of through-holes passing through from one surface to the other surface. The base material includes a first layer positioned on a side of the pressure-sensitive adhesive layer and a second layer positioned on an opposite side of the pressure-sensitive adhesive layer. The first layer includes a resin composition containing 50 to 88 wt % of a polyolefin-based resin (A); 10 to 48 wt % of a styrene-based resin and/or an acrylic-based resin (B) excluding the polyolefin-based resin (A); and 2.0 to 30 wt % of a pigment (C), and the second layer contains a polyolefin-based ionomer resin (D) as a main constituent, and the ratio of thickness between the first layer and the second layer is 80:20 to 97:3.0.
US08455081B2 Ballistic-resistant article
The invention relates to a preformed sheet comprising at least two mono-layers, each mono-layer containing a fibrous network with fibers having a tensile strength of at least about 1.2 GPa and a tensile modulus of at least 40 GPa and a binder, and a separating film on at least one of its outer surfaces, characterized in that the separating film has an areal density of between 1 and 5 g/m2. With this preformed sheet assemblies and articles offering a substantially higher ballistic protection level at a certain weight can be obtained. The invention further relates to an assembly of at least two such sheets and to a flexible ballistic-resistant article comprising said assembly.
US08455077B2 Fibrous structures comprising a region of auxiliary bonding and methods for making same
Fibrous structures, more particularly fibrous structures comprising a region of auxiliary bonding and methods for making same are provided.
US08455076B2 Paper substrates useful as universal release liners
This invention relates to a paper substrate useful as a universal release liner, as well as methods of making and using the same.
US08455075B2 Decorative stainless steel rolled sheet with embossed pattern
A decorative stainless steel rolled sheet has an embossed pattern, suitable for use as a surface finish or an interior surface finish of products, wherein a thin stainless steel sheet subjected to surface treatment including nanoceramic coating or PVD ionic coating resulting in various colors and a release sheet alone or with a nonwoven fabric layer bonded thereto by means of a hot melt adhesive layer are embossed together and bonded to each other with the embossed pattern, thus exhibiting superior bonding strength, heat resistance, fire resistance, scratch resistance, shape stability, flexibility and wrinkling resistance. In the method of manufacturing such a decorative stainless steel rolled sheet, the rolled sheet can be mass produced at uniform quality using a continuous process.
US08455072B2 Polyolefin composition for pipe system and sheets
A polyolefin composition, and pipe systems and sheets made therefrom, the composition comprising (percent by weight), 1) 10-60% of a copolymer of propylene and hexene-1 comprising from 0.2 to 10% of recurring units derived from hexene-1; 2) 10-85% of a propylene polymer selected from propylene homopolymer and a polymer of propylene with 0.1-10% of an α-olefin selected from ethylene, a C4-C10 a-olefin, hexene-1 excluded, and a mixture thereof, the propylene polymer being insoluble in xylene at ambient temperature in an amount over 85% and having a Polydispersity Index ranging from 4.5 to 12; and 3) 5-30% of a copolymer of ethylene with a C3-C10 α-olefin and optionally a diene, having an ethylene content ranging from 15 to 60% and an intrinsic viscosity value of at least 1 dl/g.
US08455064B2 UV inkjet printed substrates
The present invention relates to printed substrates for use in a variety of applications such as a label stock and flexible packaging structures. The substrates are printed with radiation curable printing ink, especially UV curable printing inks employed in UV inkjet printing processes. The substrates are coated with an ethylene-acrylic acid copolymer based coating capable of adhering and providing wet out properties with UV inkjet inks. Optionally, the coating contains an acrylic polymer. In a specific embodiment, the coating includes a major proportion of ethylene-acrylic acid and minor amounts of filler such as talc and silica. The coating can also include wax and/or pigment such as titanium dioxide. In a further embodiment, the carboxylate groups of the copolymer are neutralized with metal ions from Group Ia, IIa or IIb of the Periodic Table of the Elements, specifically, sodium.
US08455055B1 Aligning nanotubes
A method for aligning nanotubes. In one embodiment, a method is used to align nanotubes. A bath with nanotubes dispersed on the surface of a solution is provided. An attachment surface is provided to attach the nanotubes. The attachment surface is placed into the bath at an angle of around ninety degrees relative to a surface of the bath. The attachment surface is removed from the bath at a rate sufficient to apply a velocity to the nanotubes in the bath of nanotubes such that the nanotubes are aligned on the attachment surface in a direction that is substantially parallel to the direction at which the substrate is removed to form a plurality of aligned nanotubes.
US08455053B2 Separator, battery using the same, and method for manufacturing separator
A separator which includes a covering layer in which a fine framework of polyolefin resin is coated with a glass layer and an exposed layer in which the polyolefin resin is exposed is provided. A battery is provided having a cathode and an anode, an electrolyte, and a separator where the separator has the covering layer in which the fine framework of polyolefin resin is coated with the glass layer and a method for manufacturing a separator including the step of coating a fine framework of polyolefin resin with the glass layer by applying a precursor containing viscous liquid product which contains only polysilazane compound or a mixture of viscous liquid product which contains only polysilazane compound with polycarbosilazane compound to the polyolefin resin and placing the precursor applied polyoleline resin in a water bath to dry.
US08455052B2 Method for manufacturing hairline elements in case frames
A method for manufacturing hairlines in an apparatus case frame is provided. The method includes forming the case frame having primary hairlines being expressed throughout a relevant mold, coating the primary hairlines with a predetermined paint material, coating the primary hairlines to form a coated surface and scratching the coated surface to form secondary hairlines, the scratching being one of at regular and irregular lines.
US08455049B2 Strontium precursor for use in chemical vapor deposition, atomic layer deposition and rapid vapor deposition
A method of depositing a crystalline strontium titanate film on a substrate is provided, comprising carrying out an atomic layer deposition (ALD) process with strontium and titanium precursors, wherein the strontium precursor is bis(n-propyltetramethylcyclopentadienyl)strontium.
US08455039B2 Photoresist-coating apparatus and photoresist-coating method using the same
A photoresist-coating apparatus includes a substrate on which a particle-detecting area and an invalid particle-detecting area are defined, a nozzle discharging photoresist to the substrate and moving along a direction, and a particle-detecting sensor controlling on and off of the nozzle in the particle-detecting area according to presence of particles, wherein in the invalid particle-detecting area, the nozzle operates independently from detection of the particle-detecting sensor.
US08455035B2 Plant seed oil
The invention relates to a plant seed oil, comprising arachidonic acid comprising approximately 7 to approximately 26 percent by weight of the total fatty acid content, the ratio of the percentages by weight of arachidonic acid to gamma-linolenic acid being approximately 1:1 to approximately 5:1 and the ratio of the percentages by weight of arachidonic acid to dihomo-gamma-linolenic acid being approximately 1:1 to approximately 5:1. The invention additionally relates to processes for the production of this plant seed oil and formulations and uses of the plant seed oil. In particular, the invention also makes available foodstuffs and baby food that contain the plant seed oil mentioned.
US08455031B2 Beverage compositions having low levels of preservative with enhanced microbial stability
The present disclosure relates to beverage compositions comprising low levels of preservative, without the need for hot or aseptic packing. In particular, the present invention relates to beverage compositions comprising: (a) from about 20 ppm to about 50 ppm of a preservative selected from the group consisting of sorbic acid, alkali metal salts thereof and mixtures thereof; (b) from about 300 ppm to about 1500 ppm of a polyphosphate having the structure; where n averages from about 13 to about 35 and each M is independently selected from the group consisting of sodium and potassium; and (c) water; wherein the beverage composition has a pH of front about 2 to about 5 and a total hardness of from 60 to about 300.
US08455026B2 Systems and methods for processing eggs
A package of eggs is disclosed which comprises a plurality of eggs arranged in one or more rows. The eggs are further arranged in the package so that a long axis of each egg in the package is offset no more than a particular number degrees from a long axis of each other egg in the package. Further, a package of eggs is disclosed which comprises a plurality of eggs arranged in one or more rows, wherein eggs are arranged in the package such that long axes of all of the eggs in each row of eggs in the package form approximate right angles with respect to a line intercepting bottoms of receptacles holding the eggs in such a row.
US08455024B2 Appetite suppressant composition
A chewable appetite suppressant composition includes a Hoodia extract, a 5-hydroxytryptophan, a Gymnema Sylvestre, and at least one amino acid derivative. The chewable appetite suppressant composition may further include flavorants.
US08455022B2 Use of a polyphenol for the treatment of a cancerous or precancerous lesion of the skin
The present invention refers to a method for treating cancerous or precancerous lesions of the skin by administering a pharmaceutically effective amount of a polyphenol to a patient as well as to the production of a medicament thereto.
US08455021B2 Composition for prophylaxis or treatment of urinary system infection and method thereof
The present invention relates to a method of reducing risk of recurrent urethritis or recurrent cystitis comprises administering to a patient with risk of recurrent urethritis or recurrent cystitis an effective amount of a composition consisting essentially of astilbin and chlorogenic acid.
US08455020B2 Composition to enhanced HDL cholesterol and to decrease intima-media thickening in animals and humans and a method for its preparation
A method of producing a product to correct hypercholesterolemia including pulping fruits of Emblica officinalis with demineralized water to create a slurry. The slurry is treated with pectinase. The pectinase-treated slurry is filtered to create a solution. The solution is concentrated to create a product. A product having an extract of Emblica officinalis for prophylactic and for therapeutic treatment of coronary diseases, atherosclerosis, hypothyroidism and hyperthyroidism.
US08455019B2 Food or beverage composition comprising unroasted coffee solids
The present invention relates to a food or beverage composition comprising unroasted coffee solids and arabinogalactans, for example a ready-to-drink beverage.
US08455017B2 Active substance for improving hyperlipidemia and hypercholesterolemia
An active substance of medication or health product for hyperlipidemia and hypercholesterolemia comprises djulis, and which can effectively inhibit the absorption of cholesterol, advance the metabolism of cholesterol, promote the anti-oxidation and decrease the accumulation of oxidized low-density lipoprotein-cholesterol in vessel walls of organisms.
US08455016B2 Treatment for meibomian gland dysfunction or obstruction
A jojoba formulation has been developed for administration to the meibomian gland, for treatment of the symptoms of dry eye, and/or for drug delivery to the meibomian gland. The formulation incorporates the natural product jojoba wax, or components thereof, to enhance the spreading of the artificial tear as well as stabilize the tear film. The jojoba wax tear relieves irritation and discomfort as well as sharpens the blurred vision. Jojoba, because of its close chemical and physical properties to meibomian gland secretions, is effective upon topical application to penetrate the lid margin to reach the gland tissues where it may exert a therapeutic effect with or without an adjunctive agent.
US08455013B2 Use of an extract of common mallow as an hydrating agent, and cosmetic composition containing it
The present invention relates to a novel use of an extract of common mallow for restoring, maintaining or reinforcing the state of moisturization of the skin; to a cosmetic composition containing it, and also to cosmetic care methods using said composition.
US08455011B2 Adjuvant compositions for herbicides
Homogeneous aqueous composition containing from 10 to 350 g/Kg of ammonium sulfate and from 10 to 200 g/Kg of anionic esters of linear or branched C6-C20 alkyl polyglycosides, and diluted sprayable herbicidal formulation comprising the above homogeneous aqueous composition and from 0.01 to 5% by weight at least a herbicide.
US08455009B2 Amniotic membrane preparations and purified compositions and anti-inflammation methods
Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues. Placental amniotic membrane (AM) preparations described herein include AM pieces, AM extracts, AM jelly, AM stroma, and mixtures of these compositions with additional components. The compositions can be used to treat various diseases, such as wound healing, inflammation and angiogenesis-related diseases.
US08455008B2 Processed ECM materials with enhanced component profiles
Described are medical graft materials and devices having improved properties relating to their component profiles.
US08455007B2 Method to treat propolis
A method to treat propolis includes conducting at least a first extraction of raw propolis with an aqueous solvent to obtain an aqueous extract having first properties. A second extraction may be performed with an alcohol solvent on the filtration residues obtained after the first extraction. A third extraction may be performed with an oil solvent on the filtration residues obtained after the second extraction. The method applies to the production of extracts of propolis for use in the manufacture of hygiene, care, cosmetic products, food products and food supplements.
US08455006B1 Organic hair care composition and methods of manufacturing and use
An organic hair care composition made from organic ingredients, such as vegetable emulsifying wax, olive oil, shea butter, jojoba oil, and beeswax. The organic ingredients are mixingly introduced in predetermined proportions necessary to effectuate the styling, straightening, and therapeutic revitalization of hair in accordance with the included methods of manufacturing and use.
US08455002B2 Stable corticosteroid nanoparticulate formulations and methods for the making and use thereof
Disclosed are stable corticosteroid nanoparticulate formulations, methods of making and therapeutic uses thereof.
US08454991B2 Method and device for photodynamic therapy
The present invention relates to a photodynamic therapy method and uses thereof for treating an individual in need thereof, comprising administering a photosensitizer to an individual and activating the photosensitizer with a chemiluminescent light source, and/or a light-emitting diode light source, wherein the light source is in dermal contact with the individual. The present invention also relates to a device for photodynamic therapy comprising a permeable reservoir, for containing a photosensitizer formulation for skin application, the device is adapted to deliver the photosensitizer to the individual. The present invention also relates to a device for photodynamic therapy, comprising a permeable reservoir for containing a photosensitizer formulation for skin application and a light source. The light source is a chemiluminescent light source or a light-emitting diode light source and the device is adapted to deliver the photosensitizer to the individual and to irradiate a part of an individual to activate the photosensitizer.
US08454979B2 Immunopotentiating composition and process for producing same
Disclosed is an immunopotentiating composition comprising an effective immunostimulating substance which can activate natural immunity and a subsequent immunity mediated by lymphocytes without causing any damage to cells. Specifically disclosed is an immunopotentiating composition which is characterized by comprising, as an active ingredient, an immunostimulating substance produced by decomposing at least one bacterium selected from an MRE symbiotic bacteria group consisting of Bacillus sp. (FERM BP-11209), Lysinibacillus fusiformis (FERM BP-11206), Bacillus sonorensis, Lysinibacillus sp. (FERM BP-11207) and Comamonas sp. (FERM BP-11208).
US08454973B2 Modified human hepatitis C virus genomic RNA that can be autonomously replicated
The present invention provides modified hepatitis C virus genomic RNA, comprising nucleotide sequences of genomic RNA portions of two or more types of hepatitis C viruses, which comprises a 5′ untranslated region, a core protein coding sequence, an E1 protein coding sequence, a p7 protein coding sequence, an E2 protein coding sequence, an NS2 protein coding sequence, an NS3 protein coding sequence, an NS4A protein coding sequence, an NS4B protein coding sequence, an NS5A protein coding sequence, an NS5B protein coding sequence, and a 3′ untranslated region, and which can be autonomously replicated. In particular, the present invention relates to modified hepatitis C virus genomic RNA, which can be autonomously replicated by substitution of the RNA sequence portion encoding NS3, NS4, NS5A, and NS5B proteins of hepatitis C virus genomic RNA with a partial RNA sequence encoding NS3, NS4, NS5A, and NS5B proteins of a JFH1 strain shown in SEQ ID NO: 1.
US08454971B2 Glucagon/GLP-1 receptor co-agonists
Modified glucagon peptides are disclosed having enhanced potency at the glucagon receptor relative to native glucagon. Further modification of the glucagon peptides by forming lactam bridges or the substitution of the terminal carboxylic acid with an amide group produces peptides exhibiting glucagon/GLP-1 receptor co-agonist activity. The solubility and stability of these high potency glucagon analogs can be further improved by modification of the polypeptides by pegylation, substitution of carboxy terminal amino acids, or the addition of a carboxy terminal peptide selected from the group consisting of SEQ ID NO: 26 (GPSSGAPPPS), SEQ ID NO: 27 (K-RNRNNIA) and SEQ ID NO: 28 (KRNR).
US08454970B2 Compositions containing fucoxanthin extract
A composition comprises extract of fucoxanthin, wherein said composition further comprises tocotrienols and/or fucoidan. Said composition can be used to treat obesity. Said composition shows outstanding effect of weight loss. There is outstanding synergy effect among those constituents of the composition.
US08454966B2 Nanoparticles for protein drug delivery
The invention discloses the nanoparticles composed of chitosan, poly-γ-glutamic acid, and at least one bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.
US08454965B2 Method for the treatment of multiple sclerosis
A method for treating a subject with multiple sclerosis is disclosed herein. In one embodiment, a method is provided for treating a subject with multiple sclerosis that includes administering to the subject a therapeutically effective amount of an IL-21 receptor antagonist, wherein the subject has failed to respond treatment with beta interferon, thereby treating the subject.
US08454964B2 Microparticles comprising carbohydrate beads covalently linked with allergen
Microparticles are disclosed which comprise a bead essentially consisting of a cross-linked carbohydrate and an antigen covalently linked thereto. The microparticle can be used for the treatment of disorders of the immune system and in diagnostic tests.
US08454959B2 Compositions monovalent for CD28 binding and methods of use
Disclosed are domain antibodies that monovalently bind CD28. Domain antibodies that are monovalent for binding of CD28 can inhibit CD28 activity. In one aspect, a domain antibody consists of or comprises a single immunoglobulin variable domain that specifically binds and antagonizes the activity of CD28, in an aspect, without substantially agonizing CD28 activity. In another aspect, the domain antibody is a human domain antibody. The disclosure further encompasses methods of antagonizing CD80 and/or CD86 interactions with CD28 in an individual and methods of treating diseases or disorders involving CD80 and/or CD86 interactions with CD28, the methods involving administering a domain antibody to the individual.
US08454956B2 Methods for treating rheumatoid arthritis and osteoporosis with anti-IL-20 antibodies
The invention features methods and compositions for preventing or treating rheumatoid arthritis and osteoporosis by administering an antagonist of IL-20. The IL-20 antagonist may be an anti-IL-20 antibody, such as mAB 7E, that is capable of binding human IL-20 and blocking IL-20 interaction with its receptors.
US08454948B2 Long lasting drug formulations
The present invention is directed to long-lasting erythropoietin therapeutic formulations and their methods of use wherein the formulation comprises a genetically modified micro-organ that comprises a vector which comprises a nucleic acid sequence operably linked to one or more regulatory sequences, wherein the nucleic acid sequence encodes erythropoietin.
US08454943B2 Topical skin care formulations comprising plant extracts
Disclosed are compositions and corresponding methods of their use that include plant, plant parts, or extracts thereof from Michelia magnifica, Xylosma japonicum, Prunus cerasifera, Nyssa sinensis, Chimonanthus praecox, Sassafras tzumu, Inula helianthus-aquatica, Capparis bodinieri, Passiflora caerulea, Galium aparine, Boehmeria platyphylla, Colquhounia coccinea, Sageretia rugosa, Jasminum stephanense, Antirrhinum majus, Daphniphyllum oldhamii, Cuscuta chinensis, Salix variegate, Osmanthus parvifolius, Euphorbia trigona, Calliandra haematocephala, Excoecaria acerifolia, Dianthus chinensis, Myriophyllum spicatum, Nymphoides peltatum, Prunus salicina, Solanum coagulans, Elaeis guineensis, Rhododendron moulmainense, Spatholobus suberectus, Artabotrys hexapetalus, Hibiscus syriacus, Lonicera calcarata, Hydnocarpus hainanensis, Ilex fragilis, Antidesma venosum, Acacia pennata ssp. Kerrii, Althaea rosea, Millettia velutina, Themeda japonica, Dalbergia hancei, Ipomoea batatas, Photinia glomerate, Hippophae rhamnoides, Azadirachta indica, Karelinia caspica, Bauhinia touranensis, Eriobotrya japonicas, Anaphalis contorta, and/or Cratoxylum prunifolium, or any combination thereof.
US08454942B1 Cosmetic oil mousse composition
An anhydrous oil foam composition containing: (a) at least one liquid oil; (b) at least one surfactant chosen from polyglyceryl-2 laurate; (c) at least one UV filter; and (d) a propellant, wherein the composition is waterless and is capable of imparting UV protection onto a target keratinous substrate.
US08454940B2 Mixtures comprising benzotriazoles and merocyanines
The present invention relates to the use of a stabilizing composition comprising (a) an effective stabilizing amount of at least one merocyanine derivative having an absorption maximum of 350 to 400 nm, and (b) at least one UV filter selected from benzotriazole derivatives; and optionally (c) at least one excited state quencher; for the protection of body care and household products against the deleterious effects of light, heat and oxygen.
US08454938B2 Treatment of respiratory diseases
A method for treating a mammal suffering from a respiratory disease characterized by acute intermittent or chronic obstruction of the airways of the lungs, such as asthma, acute asthma, chronic obstructive pulmonary disease (COPD) and bronchiectasis comprising delivering to the lungs of the mammal a perfluorocarbon and a gas mixture comprising carbon dioxide (CO2), and pharmaceutical compositions of CO2 and perfluorocarbons are provided. The acute relief of airway obstruction provided by the said treatment provides an opportunity for concomitant or subsequent delivery of additional suitable active agent of conventional treatments.
US08454937B2 Method and composition for the site-selective delivery using viruses encapsulated in microbubbles
Methods and compositions for the site-selective delivery of a gene to a site within the body of an animal where virus not encapsulated within the microbubbles is inactivated, for example by treatment with a virus-inactivating agent.
US08454936B2 Metal chelators and methods of their use
Metal chelators of Formula I and Formula II are disclosed: or a pharmaceutically acceptable salt thereof. Also disclosed are metal chelator-targeting moiety complexes, metal chelator-targeting moiety-metal conjugates, kits, and methods of their preparation and use in diagnosis and/or treatment of diseases and conditions, including, inter alia, cancer and thrombosis.
US08454935B2 Cell permeable probe
A cell permeable probe is disclosed. The cell permeable probe includes a cell membrane translocating element, which facilitates transport of the probe into the intracellular component of a cell. The cell permeable probe may also include a plurality of binding moieties for a disease specific marker and a contrast agent.
US08454934B2 High molecular weight chelation structure
A chelation structure and method of forming and using the chelation structure. The chelation structure has a backbone that includes a linear sequence of monomeric backbone units, at least one polymer side chain, and at least one chelator side chain. The side chains are each covalently coupled to the backbone at one of the monomeric backbone units by a bond that is independently biodegradable or non-biodegradable. The chelation structure is synthesized by Radical Addition Fragmentation Transfer (RAFT), Atom Transfer Radical Polymerization (ATRP), or Free Radical Polymerization (FRP). The chelation structure, individually or in combination with a shuttle chelator, may be introduced into a mammal to bind an amount of a substance in a mammal, the substance being at least one of a metal and heme. The chelation structure has a log stability constant exceeding that of the shuttle chelator for binding the substance within cells of the mammal.
US08454930B2 Mayenite-type compound and process for production of same
The present invention relates to a mayenite-type compound in which a part of Ca of a mayenite-type compound containing Ca, Al and oxygen is substituted by at least one kind of an atom M selected from the group consisting of Be, Mg and Sr, in which the mayenite-type compound has an atom number ratio represented by M/(Ca+M) of from 0.01 to 0.50, and at least a part of free oxygen ions in a mayenite-type crystal structure are substituted by anions of an atom having electron affinity smaller than that of an oxygen atom.
US08454929B2 Continuous process for preparation of calcium thiosulfate liquid solution
An efficient process for the continuous preparation of calcium thiosulfate (CaS2O3) from lime sulfur, through oxidation is described. The process involves oxidizing calcium polysulfide intermediate in a series of reactors to produce calcium thiosulfate as a clear liquid in high concentration with minimal byproducts. The process results in the complete destruction of polythionates, permitting the calcium thiosulfate produced to be useful in certain leaching processes for precious metals. The invention further makes it possible to recycle the process water from the leaching process for use as a raw material reactant in the process for calcium thiosulfate production.
US08454926B2 Method and system for separation of solute from an aqueous solution
Disclosed is method for separating solute from an aqueous solution comprising providing a first aqueous solution substantially saturated with solute, contacting the first aqueous solution with a clathrate former under conditions sufficient to form clathrates and to precipitate the solute from the first aqueous solution, separating solute from the clathrates by removing a first stream comprising clathrates and solute, and removing a second stream comprising solute, decomposing the clathrates into the clathrate former and a second aqueous solution, the second aqueous solution comprising solute in a concentration less than the concentration of solute in the first aqueous solution, and recycling the second aqueous solution by contacting said solution with a source for the solute to form a third substantially saturated aqueous solution for use as, or in combination with, the first aqueous solution, wherein the method is continuous.
US08454924B2 Method for making cohesive assemblies of carbon
Cohesive assemblies comprising carbon are prepared by obtaining carbon in the form of powder, particles, flakes, or loose agglomerates, dispersing the carbon in a liquid halogen by mechanical mixing and/or sonication, and substantially removing the liquid halogen, typically by evaporation, whereby the cohesive assembly of carbon is formed. The method is especially suitable for preparing free-standing, monolithic assemblies of carbon nanotubes in the form of films, wafers, or discs, having high carbon packing density and low electrical resistivity. The assemblies have various potential applications, such as electrodes in batteries or supercapacitors or as electromagnetic interference shielding materials.
US08454922B2 Method and apparatus using carbon nanotubes for hydrogen storage
A method of storing hydrogen using carbon nanotubes having a diameter ranging from 0.6-0.8 nm. The hydrogen may be stored in a container which is made of another material. The carbon nanotubes may be provided inside the container for adsorbing the hydrogen.
US08454919B2 Production of precipitated silica
Precipitated silica is produced by a process that includes a step for filtering and washing an aqueous suspension (S), comprising the following steps: (a) filtering a first portion (S1) of a precipitated silica suspension (S), whereby a cake (G1) is formed and said cake (G1) is then washed and a suspension (S′1) is formed by suspending the thereby obtained washed cake (G1), notably by dilution with water; (b) filtering a second portion (S2) of the suspension (S), whereby a cake (G2) is obtained; and (c) filtering said suspension (S′1) emanating from step (a) through the cake (G2) obtained at the end of step (b), employed as a filtration precoating layer.
US08454916B2 Selective catalytic reduction (SCR) catalyst depletion control systems and methods
A dosing control system for a vehicle includes a current storage module, an adaption triggering module, and an adaption ending module. The current storage module estimates an amount of ammonia stored by a selective catalytic reduction (SCR) catalyst. The adaptation triggering module triggers a reduction of the amount of ammonia stored by the SCR catalyst to zero when a first amount of nitrogen oxides (NOx) measured by a first NOx sensor located downstream of the SCR catalyst is greater than a predicted value of the first amount of NOx. The adaptation ending module selectively ends the reduction and enables injection of dosing agent based on a comparison of the first amount of NOx with a second amount of NOx upstream of the SCR catalyst.
US08454913B2 Use of butyraldehyde oxime as an anti-nitrous agent in an operation for the reductive stripping of plutonium
The invention relates to the use of butyraldehyde oxime as an anti-nitrous agent in a plutonium stripping operation based on a reduction of this element from oxidation state (IV) to oxidation state (III). Applications: any nuclear fuel reprocessing process in which employing a compound that has the twofold property of being extractable into an organic phase and of being capable of destroying the nitrous acid therein may be useful and especially any process including one or more operations for the reductive stripping of plutonium.
US08454908B2 Automated systems and methods for preparing biological specimens for examination
The systems and methods disclosed herein permit automated preparation of biological specimens for examination. The disclosed systems and methods provide fast, efficient, and highly uniform specimen processing using minimal quantities of fluids. The methods include at least a fixing phase for fixing a biological specimen to a substrate such as a microscope slide, a staining phase for staining the specimen, and a rinsing phase for rinsing the specimen. One or more of the fixing, staining, and rinsing phases include one or more agitation cycles for distributing reagents evenly and uniformly across the specimen. The systems can be implemented as a standalone device or as a component in a larger system for preparing and examining biological specimens.
US08454903B2 Assay device for liquid sample
Disclosed is an assay device comprising liquid transport means adapted to take up a liquid sample and conduct the liquid to an analyte detection region operable to provide a test signal indicative of the presence and/or amount of an analyte in the liquid sample; the assay device further comprising a sample presence signal generation means, which is not generated by means of an immunoreaction. This sample presence signal generation means can comprise a colored portion, which is overlaid by a material (e.g. nitrocellulose) that is opaque, when dry, and translucent or transparent, when wet, to allow the colored portion to become visible to the user. In another embodiment the signal generation means comprises a color changing material which under-goes a change in its visible properties upon wetting (eg. pH indication). A third embodiment uses a mobilisable detectable which, when wetted by the sample, is carried along resulting in a streaked line parallel with the flow direction.
US08454902B2 Sensing device
A sensing device is configured that a first piezoelectric vibrator and a second piezoelectric vibrator, changing over a connection to an oscillation circuit, have the oscillation circuit in common, that an impedance of a conductive path including a first one-surface-side electrode constituting the first piezoelectric vibrator from the oscillation circuit and an impedance of a conductive path including a second one-surface-side electrode constituting the second piezoelectric vibrator from the oscillation circuit are uniform with each other, and that an impedance of a conductive path including a first other-surface-side electrode constituting the first piezoelectric vibrator from the oscillation circuit and an impedance of a conductive path including a second other-surface-side electrode constituting the second piezoelectric vibrator from the oscillation circuit are uniform with each other.
US08454894B2 Device for evaluating biochemical samples
Described is a device for evaluating biochemical samples (1), with a sample carrier (2), with an image recording means having a light-sensitive layer (3) connected to an evaluation circuit (10), and with a means for illuminating the samples (1). In order to provide simple design conditions, it is proposed that the light-sensitive layer (3), provided on the sample carrier (2), of the image recording means comprise a photoactive layer (4) based on organic semiconductors between two electrode layers (5, 6), of which the electrode layer (6) between the photoactive layer (4) and the samples (1) is translucent at least in certain regions.
US08454886B2 Durable honeycomb structures
A method for manufacturing an inorganic honeycomb structure that resists water damage after drying comprises compounding a base batch mixture including inorganic powders, a batch cross-link agent, an aqueous vehicle, and a cross-linkable batch constituent, and forming the batch mixture into a honeycomb core or skin component while reacting the cross-link agent with cross-linkable batch constituent.
US08454885B2 Method for making fused ceramic articles of near net shape
The invention is a solution impregnation and drying treatment that imparts a high temperature binder into an already formed porous green body composed of particulate batch material. The batch material includes inorganic compounds and binder. The result is reduced sag and distortion and the same or increased strength when the porous body is later fused during sintering/firing.
US08454884B2 Method of producing cellulose carbamate blown film and use of the same
The present invention relates to a cellulose carbamate spinning solution, the cellulose carbamate being dissolved in at least one ionic liquid. Furthermore, the invention relates to a method for the production of blown films in which a solution of cellulose carbamate in an ionic liquid is extruded into a coagulation bath, and also to the films produced with the method and the use thereof.
US08454882B2 Material dispensing system and method for making same
Material dispensing systems and methods for make such systems are described. The material dispensing systems employ a collapsible container that is at least partially surrounded by an elastically deformable band. The band stretches as the container is filled with a flowable composition, thereby creating potential energy which can then be used to dispense the composition in lieu of a propellant and/or pressurized container.
US08454880B2 Method and system for layerwise production of a tangible object
A method for layerwise production of a tangible object comprises repeatedly performing method cycles. Each method cycle comprises the steps of solidifying a predetermined area of an uppermost liquid layer (10) of a liquid (3) in a reservoir (2), so as to obtain a solid layer of the tangible object, and creating, above, parallel and adjacent to the solid layer, a successive uppermost liquid layer of the liquid. Said creating of the successive liquid layer is carried out by spraying such liquid onto upper parts of the contents in the reservoir. A height distribution over at least part of the surface of the uppermost liquid layer is measured by means of a measuring device (6). Based on the measured height distribution, the solidifying is carried out to compensate for unflatness of the measured height distribution.
US08454875B2 Method and device for producing molded parts with different decorative regions
The present invention refers to a method and to a device fro producing a molded port having a plurality of different decorative regions that abut each other, wherein the different decorative films (9, 10) are inserted into a molding tool (1) by a gripper (4). There they are fixed be means of sliders (8) and are then back molded with a thermoplastic material.
US08454871B2 Apparatus and method for producing light-responsive surfaces on opaque materials
The present invention provides for a method of creating a lustrous surface in opaque materials using ridge angles, and valleys of varying depths cut, imprinted or pressed into the opaque material. The combination of the light reflecting ridges, angles to reflect more or less light, and a shadow effect arising from a combination of the valley depths and the angle of the ridges allows one to use light and shadow to create a pattern or series of patterns in the opaque materials. These patterns are created using a process whereby a design is first created, then cut into a master blank using some type of manual or computer-aided method. Next, this pattern is inlaid, pressed, or imprinted into a blank panel composed of the opaque material. In some embodiments, this opaque material is allowed to set, thus creating a finished article of manufacture in the form of a panel.
US08454869B2 Stamper and stamper evaluation method
According to one embodiment, this invention determines whether a maximum value Hmax and minimum value Hmin of an HF signal obtained when a data recording portion is irradiated with a laser having a wavelength of 450 nm or less and an NA of 0.6 or more meet (Hmax−Hmin)/Hmax<0.13 . . . (1), or whether a maximum value Hmax, a minimum value Hmin, and a most frequent voltage value Have of a signal level of an HF signal obtained when a data recording portion is irradiated with a laser having a wavelength of 450 nm or less and an NA of 0.6 or more meet Hmax/Have≦1.05 . . . (2) and Hmin/Have≦0.90 . . . (3).
US08454868B2 Method for testing multilayer tablets
The present invention is related to a method for testing multilayer tablets in a multiple rotary press, in which die holes of a circulating die plate are successively filled with tablet material of different layers in succeeding filling devices, and the tablet material is compressed one layer after the foregoing layer into pressed articles having n layers by means of synchronously circulating compression punches, and the pressed articles are subsequently ejected in an unloading station and taken out, in which in a testing procedure, pressed articles with m layers are taken out after the compression in a respective unloading station and are conveyed to a testing station, wherein applies 1<=m<=n, wherein before taking out the pressed articles, at least the m-th layer is compressed more strongly than during the normal manufacture of the multilayer tablets, wherein applies m
US08454864B2 Method for making mold for forming anti-flare lens
The present disclosure relates to a method for making a mold for forming an anti-flare lens. The lens includes an optically active part and an optically inactive part. In the method, a mold core blank having a bottom surface and a top surface, is provided. The bottom surface is machined into a first surface portion, a second surface portion, and an annular surface portion. The second surface portion is located at a center of the mold core blank. The annular surface portion connects the second surface portion and the first surface portion. The first surface portion is roughened to form a roughened molding surface for forming the optically inactive part. The second surface portion is precisely machined to form a smooth molding surface for forming the optically active part. The annular surface is precisely machined to form a smooth transition surface.
US08454862B2 Method of creating ophthalmic lenses using modulated energy
This invention is related to lenses and the associated processes used to manufacture lenses. In particular, the present invention is related to a process for designing and creating bifocal, multifocal, and single vision ophthalmic lenses by modulating an energy source.
US08454853B2 Halogenated alkene heat transfer composition with improved oil return
The invention relates to heat transfer agents and heat transfer compositions containing hydrocarbon lubricating oils and halogentaed alkene heat transfer fluid that promote oil flow and provide for improved oil return. The heat transfer compositions are useful in various heat transfer systems such as refrigeration, cooling, air conditioning, chiller operations.
US08454847B2 Method of lifting off and fabricating array substrate for liquid crystal display device using the same
A method of lifting off includes forming a first material layer on a substrate; forming a photoresist pattern including first and second holes and on the first material layer; patterning the first material layer using the photoresist pattern as a patterning mask to form a material pattern having first and second grooves within the material pattern, the first and second grooves corresponding to the first and second holes, respectively; forming a second material layer on an entire surface of the substrate including the photoresist pattern and the first and second grooves; and removing the photoresist pattern and the second material layer on the photoresist pattern at the same time, wherein a portion of the material pattern between the first and second grooves and portions of the material pattern at sides of the first and second grooves constitute a line as a whole.
US08454844B2 Microneedle structure and production method therefor
A method for processing a wafer to form a plurality of hollow microneedles projecting from a substrate includes forming, by use of a dry etching process, a number of groups of recessed features, each including at least one slot deployed to form an open shape having an included area and at least one hole located within the included area. The internal surfaces of the holes and the slots are then coated with a protective layer. An anisotropic wet etching process is then performed in such a manner as to remove material from outside the included areas while leaving a projecting feature within each of the included areas. The protective layer is then removed to reveal the microneedles.
US08454836B2 Method for removing water from an organic liquid
The present invention relates to methods and apparatus for removing water and/or water-based compounds from organic liquids/fluids. In one embodiment, the present invention relates to methods and apparatus that utilize fibrous media that contains, is impregnated, or is formed from at least one super absorbent compound, where the fibrous media is formed from nanofibers.
US08454835B2 Remediation system for transition metal ions and method for same
In at least one embodiment, a method for remediating oxic water having transition metal ions comprises the steps of providing oxic water having transition metal ions. The water is introduced to a chamber. The pH is adjusted to a range from 2.5 to 7.5 forming a pH-adjusted oxic water. Thiosulfate ions are introduced and reacted with the transition metal ions to form insoluble transition metal-thiosulfate species complexes, which are immobilized forming remediated oxic water.
US08454833B2 Counter-pressure filtration of proteins
A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.
US08454828B2 Dispensing device
The invention relates to a dispensing device for a liquid medium, having a medium reservoir for accommodating the medium, having a dispensing opening for dispensing the medium from the medium reservoir, and having a pressure-equalizing channel which opens out into the medium reservoir and has a microbiologically active filter arrangement inserted therein.According to the invention, the filter arrangement has a liquid filter oriented in the direction of the medium reservoir and a bacteria filter oriented away from the medium reservoir.
US08454820B2 Electrochemical molecular recognition probes
Constitute a molecular recognition probe comprising: an electrochemically active group; an activity suppression group that suppresses an electrochemical activity of the electrochemically active group; a receptor area where a molecule of a target substance is specifically recognized; and a molecule area where a steric structure is changed as a result of molecular recognition; wherein the electrochemically active group is suppressed of its activity by the activity suppression group before the molecule is recognized and restores its activity after the molecule is recognized; or constitute a molecular recognition sensor by providing an anchor area on the molecular recognition probe and fixing it on a surface of an electrode.
US08454818B2 Method for operating copper electrolysis cells
In a process for the operation of copper electrolysis cells including a plurality of anode and cathode plates arranged vertically and parallel to each other, a longitudinal electrolyte inflow and an electrolyte outflow, the electrolyte is injected via the electrolyte inflow horizontally and parallel to the electrodes in each electrode gap always at the height of the lower third of the electrodes at a speed of from 0.3 to 1.0 m/s, with the cathode plates being arranged stationarily relative to the inflow direction. As a result, an optimized flow guidance of the electrolyte with regard to the electrodes is achieved, resulting in an increase in the limiting current density.
US08454816B1 Selective recovery of manganese and zinc from geothermal brines
This invention relates to a method for the selective recovery of manganese and zinc from geothermal brines that includes the steps of removing silica and iron from the brine, oxidizing the manganese and zinc to form precipitates thereof, recovering the manganese and zinc precipitates, solubilizing the manganese and zinc precipitates, purifying the manganese and zinc, and forming a manganese precipitate, and recovering the zinc by electrochemical means.
US08454814B2 Processes and apparatuses for treating and/or increasing dryness of a substance
There are provided apparatuses for increasing dryness of a substance. The apparatuses comprise at least one module, each of the module(s) comprising at least two electrodes adapted to submit the substance to an electric current. The electrodes are also adapted to compress the substance. There are also provided processes for increasing dryness of a substance.
US08454809B2 Modular container assembly for corrosive solutions
A modular array of containers placed in parallel for electrolytic solutions used in metals electrolysis processes, particularly for metals electrowinning and electrorefining processes, assemblable from joinable and sealable prefabricated panels with other equal or similar ones, comprising at least a pair of opposite end walls (1, 2), lateral walls (3, 4), a plurality of floor panels (5) and a plurality of intermediate transverse walls (6), the modular array of containers having a common wall between two adjacent containers, the common wall defined by said intermediate transverse walls (6). At least the intermediate walls (6) of the array of containers comprise each one a passage (7, 8) integrated to the wall for the protected feeding and distribution of the loaded electrolytic solution; these walls also being of a reduced wall width in the middle with respect to at least one of its ends and its upper and lower part; said at least one end and upper and lower part of the walls defined by edge formations (9, 10, 11, 12) in which at least one of the formations contains said passage within.
US08454808B2 Hydrogen supplemental system for on-demand hydrogen generation for internal combustion engines
A hydrogen generation system for producing hydrogen and injecting the hydrogen as a fuel supplement into the air intake of internal combustion engines. Hydrogen and oxygen is produced with a fuel cell at low temperatures and pressure from water in a supply tank. The hydrogen is directed to the air intake of the engine while the oxygen is vented to the atmosphere. The device is powered by the vehicle battery. The system utilizes an engine sensor that permits power to the system only when the engine is in operation.
US08454806B2 Systems for forming reagent with reduced background current
Systems and methods for electrochemically oxidizing components of a test-sensor reagent prior to deposition on a test sensor comprise at least a first electrode and a second electrode for contacting the test-sensor reagent. The first electrode and the second electrode may have hollow interior portions for contacting the test-sensor reagent to produce a modified test-sensor reagent having a reduced background current.
US08454804B2 Protective offset sputtering
Sputtering in a physical vapor deposition (PVD) chamber may, in one embodiment, utilize a target laterally offset from and tilted with respect to the substrate. In another aspect, target power may be reduced to enhance film protection. In yet another aspect, magnetron magnets may be relatively strong and well balanced to enhance film protection. In another aspect, a shutter may be provided to protect the substrate in start up conditions. Other embodiments are described and claimed.
US08454803B2 Processing biomass and petroleum containing materials
Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems can use feedstock materials, such as cellulosic and/or lignocellulosic materials and/or starchy materials, to produce ethanol and/or butanol, e.g., by fermentation.
US08454798B2 Paper making processes and system using enzyme and cationic coagulant combination
A method is described for making paper or paper board by applying a composition containing enzyme and cationic coagulant to papermaking pulp prior to paper forming to preferably improve drainage, retention, or both. Sheets of pulp from which paper or paperboard products are made with the method can exhibit excellent drainage, excellent retention of pulp fines, or both. The method also can be applied to other pulp treatments, such as waste water treatments. A system for making such treatments of paper furnish is also provided.
US08454797B1 Process for inkjet paper and paper produced thereby
A method for improving the print quality of paper, a process for preparing such paper and the paper produced thereby are disclosed. The method involves applying to the paper an aqueous solution comprising 0.15 to 6 weight percent calcium in the form of its hydroxide. The supersaturated solution of calcium hydroxide can be obtained from reverse osmosis of milk of lime. The paper produced by the method disclosed exhibits a surface concentration of calcium greater than 3 mg/m2 and less than 360 mg/m2 and at the same time less than 20% of a halide, nitrate, sulfate, carbonate, acetate or formate counter ion.
US08454795B1 System and method for producing bonded fiber/cellulose products
A system for forming bonded fiber/cellulose products includes a shredded paper particle manufacturing line producing shredded paper particle-based products, such as insulation, a bonded fiber/cellulose product line, and a collector for collecting a portion of the shredded paper particles generated by the shredded paper particle line for the bonded fiber/cellulose product line.
US08454792B2 Composition and method relating to a hot melt adhesive
The present invention includes compositions relating to a hot melt adhesive that includes a copolymer of butene-1, a wax, and a tackifying resin. The present invention further relates to adhesives initially exhibiting adhesion properties and subsequently non-adhesion qualities. Methods of using these adhesives are also part of the claimed invention.
US08454791B2 Method for assembling a rotor blade for a wind turbine
Method for assembling a rotor blade for a wind turbine, wherein the rotor blade has a first half shell, a second half shell and at least one shear web running in the longitudinal direction of the rotor blade.
US08454789B2 Disposable bond gap control structures
In certain embodiments, a bond gap control structure (BGCS) is placed outwardly from a substrate. The BGCS is configured to control a geometry of a bond line of a joining material. The joining material is deposited outwardly from the substrate. The substrate is bonded to another substrate with the joining material. The BGCS is at least partially removed from the substrate.
US08454785B1 Method for applying labels to cable or conduit
A method for applying labels comprising providing a system for applying the labels, supplying at least one label, guiding a cable or conduit to the labeling system with at least one guide roller, providing a label applicator for applying the label to the cable or conduit, guiding a moving cable or conduit using the at least one guide roller, providing at least one tamping device, providing a tamping pad with the at least one tamping device, applying at least one label to at least one portion of the cable or conduit with the at least one tamping device, providing at least one guide shoe assembly; and pressing the at least one label against the at least one portion of the cable or conduit using the at least one guide shoe assembly.
US08454784B2 Air-permeable composite fabric
An air-permeable composite fabric is provided. The composite fabric has an inner fabric layer, an outer fabric layer, and an intermediate vapor barrier. The vapor barrier is selected from adhesive material and an adhesive/membrane combination designed so the composite fabric has a level of air permeability to allow air flow between the first fabric layer and the second fabric layer and a variable level of water vapor diffusion resistance that decreases as air speed impinging on the composite fabric increases.
US08454780B2 Method of making laminate structures for mechanical activation
A method for producing a stretch laminate includes forming an intermediate stretch laminate. Forming the intermediate stretch laminate includes providing a first substrate and attaching an elastic film to a surface of the first substrate via an adhesive. The first substrate and the elastic film are in a face to face orientation. The intermediate stretch laminate has a residual energy of greater than or equal to 50% at a predetermined applied strain. The method of forming the stretch laminate further includes mechanically activating the intermediate stretch laminate at a strain rate of at least 100 s−1.
US08454778B2 Pneumatic tire with barrier layer and method of making the same
A pneumatic tire and a method of making a tire are provided. The tire includes a tire tread, a tire layer, and a barrier layer. The tire layer is circumferentially disposed inwardly of the tire tread and includes a first end and a second end situated adjacent each other to define a butt joint. The barrier layer includes a first end and a second end, a portion of the first end of the barrier layer overlaps the second end by about 1.5 cm or more to define a lap joint, and where the first end of the barrier layer is received between and extends beyond the butt joint such that the first end of the tire layer is sandwiched between the lap joint.
US08454775B2 Bond and stitch repair for delaminated composite
A method of repairing delaminated plies of a composite includes drilling a plurality of holes in the plies, stitching one or more tows into the plurality of holes, and tensioning the tows. The holes are disposed across an area of the plies that is delaminated. The method introduces a resin into the area of the plies that is delaminated and cures the resin. Curing of the composite can be performed prior to the stitching and the tensioning of the one or more tows and can be performed by the tensioning of the one or more tows. Optionally, one or more additional plies can be applied to the repaired area and/or a portion of the one or more tows that extends above a surface the plies can be removed.
US08454772B2 Process for the manufacturing of a decorative laminate provided with an aligned surface structure
A process for the manufacture of a decorative board, which board includes at least one thermosetting resin impregnated paper layer. A decor paper in the form of a web or a sheet, provided with a plurality of decor sections, each decor section being intended to constitute a décor of a decorative panel, is placed as a surface layer on a base layer and bonded thereto by pressing under elevated pressure. A plurality of press plates or press foils, each press plate or press foil being provided with a surface structure intended to match at least one decor section of the decor paper, are accurately positioned on top of the thermosetting impregnated paper layer before the pressing and is after the pressing separated from the laminate achieved. The laminate will hereby be provided with a décor surface with a matching surface structure which is in register with the décor of the decor paper.
US08454770B1 Non-toxic percussion primers and methods of preparing the same
A percussion primer composition including at least one explosive, at least one nano-coated fuel particle having natural surface oxides thereon, at least one oxidizer, optionally at least one sensitizer, optionally at least one buffer, and to methods of preparing the same.
US08454768B2 Near-beta titanium alloy for high strength applications and methods for manufacturing the same
A high strength near-beta titanium alloy including, in weight %, 5.3 to 5.7% aluminum, 4.8 to 5.2% vanadium, 0.7 to 0.9% iron, 4.6 to 5.3% molybdenum, 2.0 to 2.5% chromium, and 0.12 to 0.16% oxygen with balance titanium and incidental impurities is provided. An aviation system component comprising the high strength near-beta titanium alloy, and a method for the manufacture of a titanium alloy for use in high strength, deep hardenability, and excellent ductility applications are also provided.
US08454767B2 Heat treatment method, outer joint member, and tripod type constant velocity universal joint
A heat treatment method is capable of molding, by mobile quenching of induction quenching, an outer joint member of a tripod type constant velocity universal joint having excellent strength without forming hardened layers in larger radially-inner portions. Mobile quenching is performed in such a manner that a high-frequency induction heating coil is moved in an axial direction relative to an outer joint member, and thus hardened layers are formed on the roller guide surfaces. Magnetic field line cut-out bodies for cutting out generated magnetic field lines are arranged on the high-frequency induction heating coil. The larger radially-inner portions become an unquenched portion by cutting out the magnetic field lines with the magnetic field line cut-out bodies.
US08454761B1 Apparatus and system for cleaning baseball bases
An apparatus for cleaning the surface of a base, comprising: a base; a plurality of apertures flush with the surface of said base, said apertures being connected to a plurality of sub-channels and wherein said apertures are adapted to expel air; at least one air chamber operatively connected with said plurality of sub-channels; a main channel connected with said at least one air chamber; wherein said main channel is supplied from an air compressor; and a main valve located between said at least one air chamber and said main channel, wherein said main valve regulates the air flow from said main channel to said at least one air chamber, said valve being further adapted to close said main channel.
US08454758B2 Electrostatic chuck cleaning method
An electrostatic chuck cleaning process that cleans an electrostatic chuck, equipped in a chamber, for chucking and holding a substrate. This method has a plasma etching process that performs plasma etching on the electrostatic chuck, a substrate mounting process that mounts a substrate on the electrostatic chuck that was subjected to plasma etching in the plasma etching process, and a substrate removal process that removes the substrate that was mounted on the electrostatic chuck in the substrate mounting process.
US08454755B1 Methods for evacuating particles from a hard drive component
An assembly tool is provided. The assembly tool comprises a body, a first vacuum channel defined within the body, and a first locating pin attached to the body. The first locating pin has a shaft portion arranged within a surrounding portion of the body. The first locating pin is configured to engage a first alignment feature of a hard drive component at a first contact area to align the hard drive component with the assembly tool. The body is configured to couple the first vacuum channel to a vacuum source and to facilitate particle evacuation from the first contact area via the first vacuum channel when a vacuum is applied by the vacuum source.
US08454747B2 Method for producing single-crystal thin film
A method for producing a single-crystal thin film includes, for example, applying a chemical solution containing raw materials for a single-crystal thin film composed of (BaxSryCaz)TiO3 (wherein x+y+z=1.0) by spin coating on a thin film composed of BaZrO3 formed on a MgO(100) surface of a MgO(100) substrate and subjecting the applied chemical solution to heat treatment at a temperature at which orientation occurs, thereby epitaxially growing a single-crystal thin film composed of (BaxSryCaz)TiO3.
US08454746B2 Method for producing a single crystal composed of silicon using molten granules
Silicon single crystals are prepared from molten granules, by producing a first volume of molten silicon between a growing single crystal and the lower end of a silicon conical tube which is closed at its lower end, and encloses a central opening of a rotating silicon plate below which the tube extends, by means of a first induction heating coil arranged below the plate; producing a second volume of molten silicon by a second induction heating coil arranged above the plate; melting the lower end of the tube to form a passage for the second volume of molten silicon, the passage produced at a point in time when the second volume is not yet present or is less than double the volume of the first volume; and crystallizing monocrystalline silicon on the growing single crystal with consumption of molten silicon from the first and the second volume.
US08454734B2 Charging device, air handling device, method for charging, and method for handling air
The present invention relates to a charging device having a charge section (20) for charging a floating particle in an air to be handled, and an air handling device (an air cleaning device) having the charging device. The charge section (20) is constituted by a first charge section (20a) adopting an impact charging technique and a second charge section (20b) adopting a diffusion charging technique. With this structure, charging and collection of dust can be accomplished only in the casing of the device, and therefore, an increase in size of the device can be avoided.
US08454726B2 CO2 absorbent and method for CO2 capture
A solid absorbent for absorption of CO2 from flue gas, comprising: a) particles made of a cross bounded, highly porous polymer substrate, and b) CO2 absorbing functional nucleophilic groups grafted on the particle surface, is described. A method for CO2 sequestration using the absorbent is also described.
US08454725B2 Method and equipment for improving global warming and air pollution
A method and an equipment for improving global warming and air pollution are proposed, wherein hot exhaust gas generated by a thermal machine is injected into an exhaust boosting unit to be compressed and mixed with a liquid medium for atomization. Pollutants in the hot exhaust gas and heat generated due to combustion are adsorbed by the liquid medium. After the liquid medium passes a dust collecting unit, the pollutants adsorbed by the liquid medium will adhere to the dust collecting unit. Humid and hot clean air is extracted to the atmosphere, and rises to high altitudes and is cooled there. Water will drop to the ground in the form or rain or snow to cool the ground temperature and remove other pollutants in the air. Heat circulation and water circulation can be sped up to improve the situation of global warming and render more water resource to the Earth.
US08454724B2 Flexible system to remove carbon dioxide from a feed natural gas
A system and process for the removal of carbon dioxide (CO2) from a feed natural gas having variable flow rates and inlet CO2 levels.
US08454723B2 Saprolite neutralisation of heap leach process
A heap leach process for the recovery of nickel and/or cobalt from a laterite ore, said process including the steps of: a) providing one or more heaps of a nickeliferous laterite ore; b) leaching the ore in a heap leach step by applying acid to one or more heaps to provide a pregnant leach solution; c) neutralizing the pregnant leach solution with ground saprolite ore; and d) recovering the nickel and/or cobalt from the neutralized pregnant leach solution.
US08454722B2 Method for reclaiming lead
A method for reducing tin in lead bullion has the steps of adding an Arrhenius base to a kettle containing lead bullion and tin, adding a byproduct of conventional detinning to the kettle, agitating contents of the kettle, and removing a layer of slag from the kettle. The disclosed method removes tin via chemical oxidation, adds lead via chemical reduction of an oxide from the byproduct of conventional detinning, and preserves most of the antimony content of the lead bullion.
US08454720B1 Air condenser housing screening apparatus
A air condenser housing screening apparatus includes a pair of female mating members each comprising an elongated panel having a first side and a second side. A female receiver is mounted on the first side. A pair of male mating members is provided and each is removably engageable with one of the female mating members. Each of the female mating members has one of a plurality of fasteners coupled thereto. The fasteners are configured to releasably couple the female mating members to an air condenser housing. A screen mesh is positioned between coupled pairs of the female and male mating members to cover a portion of the housing with the screen.
US08454718B2 Working vehicle having cooling system with suction device
A work vehicle is provided comprising: a main frame including an engine compartment; an engine located in the engine compartment; and a cooling system comprising a rotating fan apparatus and a cooling assembly. The cooling assembly may comprise a heat exchanger for transferring energy in the form of heat from a coolant fluid to air and a filter apparatus positioned adjacent an engine-compartment side of the heat exchanger. The air may be moved through the heat exchanger by the fan apparatus. The filter apparatus may filter the air before the air passes through the heat exchanger. The filter apparatus may comprise filter structure and a suction device for removing debris from the filter structure. The suction device preferably expels the debris outside of the engine compartment.
US08454716B2 Variable flow particle separating structure
A particle separating structure for use with a turbine engine. The particle separating structure includes a main housing, first swirling structure, and second swirling structure. The first swirling structure is provided for swirling cooling fluid passing through a first cooling fluid flowpath defined in the main housing. The second swirling structure is provided for swirling cooling fluid passing through a second cooling fluid flowpath defined in the main housing. The first swirling structure is positionable in at least two positions, a first position allowing cooling fluid to pass through the first cooling fluid flowpath and a second position allowing cooling fluid to pass through the first and second cooling fluid flowpaths. The swirling of the cooling fluid causes particles in the cooling fluid to pass to a particle discharge zone while the cooling fluid passes out of the main housing through a cooling fluid outlet.
US08454713B2 Natural gas production method utilizing a gas dynamic laser, with cogeneration of electrical power
A method for producing natural gas is provided. a gas dynamic laser is powered by a gas, such as carbon dioxide, while the same gas is converted by a catalytic converter heated by the beam of the laser. Other gases can be formed simultaneously in other catalytic converters heated by the laser beam. The resulting converted gases can be used to produce a fuel gas. Excess heat and/or by-products of the process can be used to produce electricity.
US08454710B2 Process for producing azo compounds, pigment dispersion, coloring composition, ink for inkjet recording, coloring composition for color filter, and color filter
To provide a process for producing an azo pigment showing excellent coloring characteristics such as tinctorial strength and hue and showing excellent fastness such as light fastness and ozone fastness, an azo pigment dispersion, a coloring composition, and an ink for inkjet recording. process for producing, for example, an azo pigment represented by the general formula (9), which includes a step of preparing a solution containing a compound represented by the following general formula (7) and an acid, and a step of bringing the solution in contact with a diazonium salt (8) derived from a heterocyclic amine,
US08454706B2 Antibiotic delivery system and method for treating an infected synovial joint during re-implantation of an orthopedic prosthesis
An antibiotic delivery system including an intramedullary stem that is adapted to be removably mounted into a medullary canal of a bone. The stem includes a body having an inlet adapted to be in fluid communication with a source of liquid-borne antibiotic and a plurality of outlets disposed along the stem. A channel extends between the inlet and the plurality of outlets for delivering a fluid-borne antibiotic from the inlet to the plurality of outlets so as to distribute the antibiotic along the medullary canal in a controlled fashion. A method of treating an infected joint during a two-stage re-implantation of an orthopedic implant is also disclosed.
US08454704B2 Method and apparatus for re-attaching the labrum of a hip joint
A method and apparatus for re-attaching the labrum of a hip joint.
US08454701B2 Surgical method for implanting a housing-interface assembly in a bone wall
A surgical method for positioning an extraoral bone-anchored implant device in a receiving bone site of a patient, the patient being a human being or an animal, including the following successive steps: a step of preparing the receiving bone site, a step of impacting the implant in the opening formed in the receiving bone site; a step of leveling the implant and the surrounding bone structure and making them continuous, during which the external table of the bone structure is rubbed at its part surrounding the implant, then bone fragments are positioned on the rubbed parts of the external table of the bone structure, then the bone fragments are covered with a membrane to hold the bone fragments in position, the membrane being attached to the bone structure on one side and to the implant on the other side, so as to prevent bone proliferation on the implant.
US08454697B2 Method and apparatus for the treatment of tissue
This disclosure presents methods and devices for treating a defect in soft tissue of a patient. The methods and devices can employ fixation delivery apparatuses and fixation apparatuses positioned, at least in part, in or on the soft tissue to be repaired. In some aspects, these techniques include the use of this includes a fixation apparatus that includes at least one bone anchor connected to at least one tissue anchor by a shortenable elongate member.
US08454695B2 Selectively expanding spine cage, hydraulically controllable in three dimensions for enhanced spinal fusion
A selectively expanding spine cage has a minimized diameter in its unexpanded state that is smaller than the diameter of the neuroforamen through which it passes in the distracted spine. The cage conformably engages between the endplates of the adjacent vertebrae to effectively distract the anterior disc space, stabilize the motion segments and eliminate pathologic spine motion. The cage enhances spinal arthrodesis by creating a rigid spine segment. Expanding selectively, the cage height increases and holds the vertebrae with fixation forces greater than adjacent bone and soft tissue failure forces in natural lordosis. Stability is thus achieved immediately, enabling patient function by eliminating painful motion. The cage shape intends to rest proximate to the anterior column cortices securing the desired spread and fixation, allowing for bone graft in, around, and through the implant.
US08454694B2 Interbody device and plate for spinal stabilization and instruments for positioning same
Systems, methods and devices for providing stabilization between first and second vertebrae are provided. More particularly, in one form a system includes an implant configured to be positioned in a disc space between the first and second vertebrae and a freestanding plate for engagement with extradiscal surfaces of the first and second vertebrae. The system also includes an insertion instrument with an engaging portion configured to releasably engage with the implant and the plate such that the implant and plate can be positioned together relative to the first and second vertebrae. In one aspect, an angular orientation of the implant relative to the plate is adjustable when the implant and the plate are engaged by the instrument. In this or another aspect, the implant and plate are held in a contiguous relationship when engaged by the instrument. However, different forms and applications are also envisioned.
US08454692B2 Systems and devices having hydromagnetic joints and hydromagnetic springs
A hydromagnetic joint includes a first joint part having a first magnetic element with a magnetically charged surface, and a first buoyant element coupled with the first magnetic element, and a second joint part including a second magnetic element having a second magnetically charged surface that opposes the first magnetically charged surface of the first magnetic element, and a second buoyant element coupled with the second magnetic element. The hydromagnetic joint has a liquid disposed between the first and second joint parts. The first and second joint parts are moveable relative to one another and are in fluid communication with the liquid. The first and second magnetically charged surfaces have a common polarity and repel one another.
US08454691B2 Surgical correction of ptosis by polymeric artificial muscles
A surgical procedure is described for the restoration of eyelid function in individuals suffering from ptosis or upper eyelid droop syndrome that makes a patient unable to voluntarily fully raise an eyelid. The surgical procedure includes implantation and suturing of eye drop (pH) activated and actuated fibrous contractile and expansive artificial muscles such as pH active hydrogels of polyacrylonitrile (PAN) artificial muscles that are surgically implanted and sutured under the superior palpebral conjunctiva in a serpentine parallel configuration with respect to the tarsal (meibomian) glands of the upper eyelid and anchored to the tissues of superior fornix.
US08454687B2 Lens inserter apparatus and method
An embodiment in accordance with the present invention provides an apparatus and method for inserting a lens into a flap or pocket in the cornea. The apparatus includes a handle, a plunger extending movably through the lumen of the handle, wherein the plunger includes a distal segment which extends beyond the distal end of the handle, an actuator coupled to the plunger configured to provide movement to the plunger, and a leaf extending from the distal end of the handle and configured to hold the lens to be inserted into the eye, wherein the leaf defines a slot configured to enable loading the lens onto the inserter.
US08454685B2 Low profile transcatheter heart valve
An implantable prosthetic valve, according to one embodiment, comprises a frame, a leaflet structure, and a skirt member. The frame can have a plurality of axial struts interconnected by a plurality of circumferential struts. The leaflet structure comprises a plurality of leaflets (e.g., three leaflets arrange to form a tricuspid valve). The leaflet structure has a scalloped lower edge portion secured to the frame. The skirt member can be disposed between the leaflet structure and the frame.
US08454684B2 Heart valve holder for use in valve implantation procedures
A valve holder for a prosthetic valve having a stent comprising a stent base and multiple commissure posts projecting from the stent base, the valve holder including a connector hub, a plurality of legs connected to the connector hub, each leg having an elongate portion and a commissure post engaging plate, a sliding member slideably connected to each leg of the plurality of legs and positioned between the connector hub and the commissure post engaging plates of the plurality of legs and slideably positionable at a first position relative to the connector hub with the commissure post engaging plates in an uncompressed configuration and a second position relative to the connector hub with the commissure post engaging plates in a compressed configuration, and a handle extending from the connector hub.
US08454682B2 Anchor pin stent-graft delivery system
A stent-graft delivery system includes a stent-graft including a proximal anchor stent ring. The proximal anchor stent ring includes proximal apexes and anchor pin structures extending proximally from each of the proximal apexes. The anchor pin structures include anchor pin connecting arms and anchor pins. The anchor pin structures are tucked together to accommodate small catheter sizes. Further, the anchor pins reduce or eliminate migration of the stent-graft. Further still, the anchor pin connecting arms are long and flexible thus distributing stresses in a way that improves the load carrying capacity of the anchor pins and allows flowering of the graft material of the stent-graft prior to release of the anchor pins structures.
US08454679B2 Endovascular conduit device for increasing safety of cardiac lead extraction and other vascular procedures
An endovascular conduit device and method for use during cardiac lead extraction and other vascular procedures is presented. The endovascular conduit device includes an outer-sheath, a conduit member, a lumen member, and an inflation member to control the flow of fluid within the conduit member. The endovascular conduit device may be positioned intravascularly as cardiac lead extraction or other procedures are performed. If necessary, as in the case of a vascular tear, the endovascular conduit device further includes expandable members that are activated to allow blood to be forced into the channel of the conduit member. Blood may then be contained and directed safely to bypass the area of vessel injury. In doing so, a catastrophic circulatory collapse or shock is prevented.
US08454678B2 Prosthetic implants including ECM composite material
Described are preferred prosthetic valve devices including a first extracellular matrix material having a second extracellular matrix material deposited thereon. The preferred materials are made by culturing cells in contact with an extracellular matrix graft material in a fashion to cause the cells to biosynthesize and deposit extracellular matrix components on the material. The cells are then removed to provide the extracellular matrix composite material. In preferred embodiments, the prosthetic valve devices are configured for use in vascular applications.
US08454672B2 Warming device for perioperative use
A warming device for perioperative use includes a clinical garment and a convective thermal blanket supported on an inside surface of the clinical garment. A mechanism may be provided to releasably attach the thermal blanket to the clinical garment.
US08454666B2 Slide-type anti-backout device for prosthesis
A slide-type cervical plate includes an anti-backout device (2) preventing the vertical movements of the bone anchor screws (3) and which consists of first vertical-blocking elements (71) capable of deforming elastically in a first direction so that an anchor screw (3) can be introduced into the corresponding bore (4) and of second vertical-blocking elements (8) capable of deforming elastically in a second direction different than the first so that another anchor screw (3) can be fitted into another bore (4), the first and second blocking elements deforming elastically when a combined external load in a vertical direction and in rotation in the clockwise direction is applied to the anchor screws (3).
US08454665B2 Multi-purpose bone plate system
A multi-purpose bone plate system comprises a set of sterile malleable bone plates, an adjustable bending and contouring tower with adjustable angulation and compression slots and a set of bone plates with angulation and compression slots positioned at pre-selected locations to aid three-dimensional shaping of the bone plate. The surgeon inserts the sterile bone plate template to surround the fractured bone and works the template to acquire the physical shape of the fractured bone, inserts the template into the tower to set the adjustable angulation and compression slots of the tower. Now a symmetrical bone plate is inserted into the tower and bent to a shape that replicates the shape of the bone plate. The three-dimensionally shaped bone plate is sterilized and is attached by screws or nails surrounding the fractured bone segment and provides support to fractured bone segments during healing of the bone.
US08454658B2 Surgical bone anchoring device and spinal column fixation system
A bone anchoring device for a spinal column fixation system includes an anchoring part, a bearing part for mounting at least one connection element thereon and a fixing element. The connection element is adapted for fixing to at least two bone anchoring devices. The anchoring part and the bearing part are mounted on each other, movable relative to each other in an assembly position and fixable relative to each other by the fixing element in an implantation position. The fixing element is of integral construction and has a proximal fixing element section, a distal fixing element section and a predetermined break-off area formed between the proximal and distal fixing element sections. The distal fixing element section has a receptacle for engagement with a tool for transferring the bone anchoring device from the assembly position to the implantation position. The device may be part of an improved spinal column fixation system.
US08454653B2 Compound barb medical device and method
A compound barb medical device includes a body portion and at least one barb extending therefrom. The at least one barb defines an inner surface. The inner surface includes a first portion disposed at a first orientation relative to a longitudinal axis of the body portion and a second portion disposed at a second orientation relative to the longitudinal axis. The at least one barb is made from a shape memory material which can be deformed into a temporary shape from a permanent shape. The barb projects from the body portion in a first position relative to the body portion when in the permanent shape and in a second position when in the temporary shape.
US08454649B2 Device and method for controlling injection of liquid embolic composition
A liquid embolic delivery system is provided for trapping an injected liquid embolic composition to prevent the liquid embolic from solidifying or otherwise passing outside of an embolization area. The delivery system includes a catheter for delivery of a liquid embolic composition and a containment member positioned at a distal end of the catheter which is shaped to trap the liquid embolic composition delivered through the lumen of the catheter. The containment member is formed as a brush, nest, sponge, swab, flexible sack, or other shape into and around which the liquid embolic composition is injected. The liquid embolic composition is trapped or meshes with the containment member during solidification containing the liquid embolic and preventing the embolic composition from passing into the blood stream.
US08454648B1 Locking device for a prostate immobilizer
A prostate immobilizer has a shaft with a fluid passageway extending therethrough, a balloon affixed over an end of the shaft such that the fluid passageway communicates with an interior of the balloon, a lumen extending within the shaft so as to have an end opening adjacent an end of the balloon, and a device for locking a position of the shaft. The device has a positioning member having a stem portion extending from a head portion, and a locking member having a locked position and an unlocked position. The locking member cooperates with the stem portion of the positioning member so as to fix a position on the shaft. A channel is formed in the head portion so as to receive the shaft therein.
US08454643B2 Tattoo needle housing and assembly
The present invention provides a tattoo needle housing, including: a substantially hollow prismatic structure configured to surround a plurality of tattoo needles, wherein the substantially hollow prismatic structure includes a bottom edge portion at one end thereof that has a shape that substantially matches a collective shape of the tips of the plurality of tattoo needles, and wherein the substantially hollow prismatic structure includes an opening manufactured into one or more of a top surface and a bottom surface thereof.
US08454637B2 Scoring balloon with offset scoring elements
A scoring balloon (10) includes a balloon portion (12) having a balloon wall substantially even in wall thickness; a plurality of sets of scoring elements (24-28) disposed on the balloon (12); each set of scoring elements including a plurality of scoring elements (30) arranged longitudinally in series, wherein adjacent scoring elements (30) in the series are longitudinally spaced from one another so as to provide gaps (32) between said adjacent scoring elements; each set of scoring elements being radially spaced relative to the other sets of scoring elements around the balloon (12), wherein the scoring elements of one set are longitudinally offset relative to the scoring elements of an or each adjacent set of scoring elements.
US08454634B2 Vessel sealing devices
A device for temporarily sealing an opening in a blood vessel is provided. The device comprises a cutting mechanism for creating an opening in a blood vessel and a seal for sealing the opening in the blood vessel. The seal is delivered through an inner lumen of a tool body coupled to the cutting mechanism. Methods for using the device to construct an anastomosis between two vessels are also provided.
US08454630B2 Endoscopic clipping device
A hemostatic clipping device is provided. The device includes first and second elongate arms, each arm comprising distal and proximal end portions, the arms being connected to allow relative motion between the first and second arms, the distal portion of each of the first and second arms further comprising a track blindly defined from a distal end of each arm toward the proximal portion of each arm. A clip is slidably disposed between the opposed distal portions of each of the first and second arms, the clip comprising first and second fingers each with distal and proximal portions, the proximal portions of the first and second fingers being fixed together to bias the distal portions of the first and second fingers toward each other, the first and second fingers each further comprising a pin extending radially outward from the distal end portion thereof.
US08454629B2 Biopsy devices and methods
A method of marking and optionally treating a tissue sample, the method having the steps of: (a) providing an instrument including a needle having an opening and a clip delivery device within the needle, wherein the clip delivery device includes an opening coexisting with the opening of the needle; and (b) delivering a clip to a biopsy site, wherein the clip includes an encasement adapted to provide treatment to tissue sample; wherein delivery of the clip is essentially free of a step of longitudinal re-positioning of greater than about 3 mm by the user of the needle or clip delivery device so that the clip is precisely deployed to a central portion of the biopsy site.
US08454621B2 Instruments and methods for spinal implant revision
Instruments and methods are provided for re-positioning and extracting spinal implants in a space between vertebrae. The instruments can include rotator instruments, hook instruments, and extractor instruments engageable to the implant. A method for manipulating a spinal implant in a space between vertebrae includes positioning a spinal implant in the space between vertebrae; engaging the spinal implant with a hook member at a distal end of a hook instrument; pulling the spinal implant toward an opening into the space between the vertebrae; grasping the spinal implant with an engaging assembly of an extractor instrument; and removing the spinal implant from the space with the extractor instrument.
US08454620B2 Systems and methods for reducing fractured bone using a fracture reduction cannula with a side discharge port
An elongated shaft is sized and configured to establish an access path to bone having an interior volume occupied, at least in part, by cancellous bone. The elongated shaft includes a generally closed distal end portion and a side opening spaced from the closed distal end. A first tool is sized and configured to be selectively inserted into the shaft and selectively removed from the shaft. The tool includes a region that, when the first tool is inserted into the shaft, is capable of being aligned with and advanced through the side opening to project outside the side opening and contact cancellous bone. A second tool is sized and configured, upon removal of the first tool from the shaft, to introduce into the shaft a bone filling material for discharge through the side opening into the cancellous bone contacted by the first tool.
US08454612B2 Method for vertebral endplate reconstruction
Embodiments relate generally to tissue anchors and methods of delivering same to the intervertebral disc or other sites within the body. In some embodiments, the anchors provide increased pull-out resistance, stability and/or contact with tissue involving a reduced amount of penetration. In some embodiments, delivery methods are minimally invasive and can include linear, lateral, and off-angle implantation or driving of anchors along, against or within tissue surfaces. Several embodiments disclose anchors and anchoring systems that effectively reconstruct or augment vertebral endplate surfaces.
US08454605B2 Blocking device for a broken or cracked bone
Locking mechanism for a broken or fractured bone, comprising a medulla nail with a proximal portion which may incorporate perforations and a distal portion, and at least one locking aid, characterized in that the distal portion has a surface structure which is designed so that the bone can be stabilized by means of the medulla nail due to the at least one locking aid acting on the surface structure of the nail through the bone from outside, preferably preventing it from rotating and/or being subjected to axial stress.
US08454602B2 Apparatus, system, and method for performing an electrosurgical procedure
The present disclosure provides a bipolar forceps. The bipolar forceps includes a housing having a handle assembly including a movable handle and one or more shafts. An end effector assembly operatively connects to a distal end of the shaft and includes a pair of first and second jaw members. A solenoid is in operative communication with the movable handle and operatively couples to a drive rod operatively coupled to at least one of the first and second jaw members for causing movement thereof. One or both of the first and second jaw members includes one or more teeth configured to engage one or more teeth located on the drive rod such that rotation of the solenoid imparts one of longitudinal and rotational movement of the drive rod such that at least one of the first and second jaw members moves between the open and closed positions.
US08454597B2 Endoscopic devices and related methods of use
Embodiments of the invention include a medical device including a handle portion, an end effector assembly, an elongate member connecting the handle portion and the end effector assembly, and one or more treatment devices extendable through the elongate member and end effector assembly. The end effector assembly includes an electrode assembly configured to cauterize tissue. The treatment devices may include an elongate cutting member with a safety tip. The treatment devices may include a multi-lumen catheter with a lumen configured to deliver fluid and another lumen configured to accommodate an injection needle, a cutting member, or other therapeutic or diagnostic devices.
US08454592B2 Medical device system for determining contact between first medical device and second medical device
The medical device system includes: first and second medical devices that are used in the body cavity and surfaces of which have conductivity; a first electrode electrically connected to the surface of the first medical device; a second electrode electrically connected to the surface of the second medical device; a resistance measuring unit for measuring an inter-device resistance value between the first electrode and the second electrode; a threshold storing unit for storing a predetermined lower limit threshold of the inter-device resistance value; a determining unit for determining, when the inter-device resistance value is lower than the inter-device resistance threshold, that the first medical device and the second medical device come into contact with each other; and a warning generating unit for generating a warning.
US08454591B2 Subcutaneous electric field distribution system and methods
Apparatus and methods for dynamically controlling electric field distribution within tissue disposed at various depths beneath the skin at a target region of a patient's body by independently controlling the electric potential of each of a plurality of electrodes in relation to the electric potential of a ground pad. By controlling electric field distribution during a procedure, a target tissue at particular depths beneath the skin can be selectively heated relative to adjacent non-target tissue. At least one of the electrodes and the ground pad may comprise a spiral inductor comprising a substantially planar spiral of electrically conductive material.
US08454587B2 Closed loop catheter coolant system
A coolant system for a cryoablation or treatment probe that includes a compressor and condenser having a low pressure inlet side and a high pressure outlet side, wherein the outlet side passes through a heat exchanger and is cooled by the inlet side and conditioned for injection to a catheter inlet. A vacuum return system connectable to the catheter outlet draws thermally expended coolant from the catheter and returns it to the low pressure inlet side. A motorized pressure regulator between the heat exchanger and the catheter inlet determines the pressure of coolant passing into the catheter, regulating the cooling rate for a selected mapping or ablation regimen. A coolant reservoir feeds into the low pressure inlet side and receives a return flow of excess fluid from a branch off the outlet side of the compressor.
US08454585B2 Flexible shaft extender and method of using same
An extender for use in an electro-mechanical surgical system that includes a surgical attachment that may be detachably coupled to an electro-mechanical driver device via a flexible shaft. The extender is a substantially rigid extender that includes a proximal end that may be detachably coupled to a distal end of the flexible shaft. The extender also includes a distal end that may be detachably coupled to the surgical attachment. The extender also includes at least one rotatable drive shaft configured to engage and be secured with a respective rotatable drive shaft of the flexible shaft such that rotation of the respective rotatable drive shaft of the flexible shaft by the electro-mechanical driver device causes the at least one rotatable drive shaft of the extender to rotate, thereby rotating a complementary connector of the surgical attachment so as to operate the surgical attachment. The extender may include a memory unit and a data cable that transfers data from the memory unit to an electro-mechanical driver device. Additionally or alternatively, the extender may include a data cable that transfers data from a memory unit in the surgical attachment to the electro-mechanical driver device. Advantageously, the extender is autoclavable.
US08454581B2 Infusion pump systems and methods
Some embodiments of an infusion pump system can include a controller in which one or more features sets to be provided by the controller are enabled or disabled based upon the particular pump device that is connected to the controller. For example, in some embodiments, one or more advanced features of the controller are available to the user only when a first type of pump device (e.g., having predefined settings stored therein) is connected to the controller, and those advanced features of the controller are disabled when a second type of pump device is connected to the controller.
US08454579B2 Medical connector with automatic valves and volume regulator
Some embodiments disclosed herein relate to a medical connector having a backflow resistance module configured to prevent fluid from being drawn into the connector when a backflow inducing event occurs. In some embodiments, the backflow resistance module can include a variable-volume chamber configured to change in volume in response to a backflow-inducing event and a check valve configured to resist backflow. In some embodiments, the medical connector can include a fluid diverter configured to direct fluid flowing through the medical connector into the variable volume chamber to prevent fluid stagnation therein. In some embodiments, the medical connector includes a body member, a base member, a seal member, a support member, and a valve member.
US08454577B2 Catheter having an auxiliary lumen for use with a functional measurement wire
The present invention relates to a surgical catheter, and more particularly, a balloon catheter having an auxiliary lumen configured to permit the advancement of a functional measurement wire to a treatment site. The auxiliary lumen communicates with a working lumen that is configured to permit the advancement of a guidewire and the functional measurement wire, so that the guidewire and functional measurement wire may selectively be advanced to the treatment site during a surgical procedure.
US08454573B2 Medicament administration apparatus
An apparatus for removal of premixed drugs or reconstitution of lyophilized drugs and for the injection of the reconstituted drug into the patient. The apparatus includes a syringe assembly and an adapter assembly that can be removably connected to a medicament container containing a premixed drug or lyophilized medicament. The syringe assembly of the apparatus includes a liquid chamber between the forward end of the body portion and the piston and a syringe cannula assembly. The syringe cannula assembly, which can be removably interconnected with the body portion, comprises a cannula support and a hypodermic needle sealably connected to the cannula support. The adapter assembly comprises an adapter preferably molded from a moldable plastic that includes a top wall, an adapter cannula connected to and extending from the top wall and a variety of connectors connected to the top wall for removably interconnecting the adapter with the medicament container. The adapter assembly further includes syringe connector member connected to the top wall for removably interconnecting the syringe with the adapter in a manner to uniquely position the syringe cannula within the lumen of the adapter cannula wherein it is completely shielded from external contamination to prevent print damage and injury to the user.
US08454571B2 Disposable absorbent article having a frangible bonding agent
A disposable absorbent article that includes a frangible bonding agent for maintaining the absorbent article in a predetermined configuration. The frangible bonding agent may be disposed on a fastening system in order to maintain one or more portions of the fastening system in a particular position during manufacturing but still provide an easy-to-open fastener when used by a consumer.
US08454567B2 Multi-conduit connectors and methods for negative pressure wound therapy
Multi-conduit connector apparatuses for use in negative pressure wound therapy (NPWT) apparatuses to wound dressing, and methods for installing multi-conduit connector apparatuses in NPWT apparatuses.
US08454563B2 Trocar and cannula assembly having improved conical valve, and methods related thereto
A trocar and cannula assembly with improved conical valve that incorporates a plurality of ribs to restrict and/or otherwise influence valve movement, and a plurality of improved convolutes and bumps to enhance performance characteristics.
US08454561B2 Fluid delivery systems for delivery of pharmaceutical fluids
An assembly for connection to a system for injecting a patient is disclosed. The assembly includes an enclosure, a compartment incorporated into the enclosure, a connector, and an output. The compartment is adapted to accept a pharmaceutical container. At least one sealing member is adapted to reversibly seal the compartment. The connector is adapted to establish a fluid connection with a pharmaceutical container in the compartment. The outlet is in fluid connection with the first connector and adapted to connect to the injector.
US08454560B2 Syringe mount for a medical fluid injector
In certain embodiments, a syringe mount of the invention may include a plate, an actuator, and one or more movable members located between the plate and the actuator. Each of the plate and the actuator may have an orifice defined therein, and an imaginary reference axis of the syringe mount may extend through one or both of these orifices. The actuator may be movable relative to the plate in a direction substantially perpendicular to the reference axis. Further, the moveable member(s) may be designed to move (e.g., pivot) toward the reference axis due to movement of the actuator from a first position to a second position and to move (e.g., pivot) away from the reference axis due to movement of the actuator from the second position to the first position.
US08454559B2 Hypodermic syringe with retractable needle
Hypodermic syringe having a barrel which with an inner wall thereof defines a reservoir, a closing-off device near the first end of the barrel, and a plunger that is movably placed in the second end of the barrel, wherein the closing-off device comprises a circumferential wall that sealingly abuts the inner wall of the barrel, at the side facing away from the nozzle is provided with a recess extending along a centre line of the closing-off device and over the full width thereof, which recess merges into the through-opening, with in the recess two diametrically opposite flexible locking members, extending in the longitudinal direction of the recess and towards the inner wall, which locking members engage into diametrically placed locking grooves in the inner wall, and at the side facing away from the nozzle, at a circumferential part of the closing-off device situated outside of the recess, is provided with two diametrically opposite and radially outwardly extending blocking members, that engage in diametrically placed blocking grooves in the inner wall.
US08454557B1 Infusion pump system and method
Some embodiments of an infusion pump system may be configured to detect when at least one component of the pump system is exposed to an impact above a threshold level. In particular embodiments, the infusion pump system can be equipped with an impact detection system that can sense when an impact above the threshold level has occurred to the pump device, which thereby enables the infusion pump system to initiate appropriate patient safety countermeasures.
US08454555B2 Cardiac related neural activity
The present invention relates to a medical device for analyzing cardiac related input signals. The device is capable of receiving an ECG-signal and a nerve activity signal, such as vagus nerve signal in order to detect a cardiac related neural activity, such as epilepsy. The device is programmed for detecting a trigger feature (e.g. the R-peak) in the signal and extracting a nerve activity signal segment from the nerve activity signal in response to detecting the trigger feature. An activity related feature is generated either based on a combined signal obtained from a number of nerve activity signal segments, or as a segment-based activity related feature obtained from a number of nerve activity signal segments. Moreover, the device is adapted for comparing the activity related feature to a predefine criterion in order to detect the cardiac related neural activity.
US08454553B2 Disposable extracorporeal blood circuit and apparatus for the extracorporeal treatment of blood
A rigid tubular piece (24) and a cassette assembly (10) for extracorporeal blood circulation having the rigid tubular piece are disclosed. The rigid tubular piece is used for submitting fluid circulating therein to measurements and includes a protrusion or a recess in correspondence of at least an end connector. A blood treatment medical apparatus using the cassette assembly is also disclosed. The apparatus is able to detect if the right rigid tubular piece is in proper position before authorizing measurements of a blood property.
US08454552B2 Method for constructing an instrument with a covered bore for subcutaneous implantation
A method for constructing an instrument with a covered bore for subcutaneous implantation is provided. An incising body is formed by defining a non-circular coaxial bore and sharpening a cutting edge extending from a bottom distal end beyond the opening of the coaxial bore and affixing an attachment point at a top distal end. A plunger is constructed sized to fit within the coaxial bore. The plunger is inserted in the bore of the incising body. A cover is affixed to the attachment point, wherein the cover extends down to the bottom distal end and, when closed, the cover encloses the opening proximal to the cutting edge.
US08454551B2 Removable adapter for phacoemulsification handpiece having irrigation and aspiration fluid paths
Current phacoemulsification handpieces require rigorous cleaning after each procedure because the aspiration and irrigation pathways for fluids are integral to the handpiece. According to the present invention, a removable horn extension and nosecone may be used with a phacoemulsification handpiece to allow for disposable fluid pathways exterior to the handpiece. This will reduce the cleaning time and effort, reduce cross-contamination, and increase the lifespan of the handpiece. Furthermore, the current invention allows different horn extensions to be used to excite different motions at the tip of the handpiece, depending on the preference of the surgeon.
US08454548B2 System and method for plasma reduced platelet collection
A method and apparatus for collecting plasma reduced platelets potentially suspended in a synthetic solution from a donor. Whole blood is drawn from the donor and introduced into a separation chamber. Platelets are extracted from the separation chamber into a container, using, for example, surge (with anticoagulated plasma or a synthetic solution) or push methodologies. The remaining blood components in the separation chamber are returned back to the donor. The steps of drawing whole blood and introducing the whole blood into the separation chamber, extracting platelets from the separation chamber into the container, and returning the remaining components in the chamber back to the donor are repeated. The sequestered platelets in the container are reintroduced into the separation chamber, whereupon a plasma reduced platelet product is extracted.
US08454547B2 Device, system, and method for controllably reducing inflammatory mediators in a subject
Devices, systems, and methods are provided for controlling an inflammatory response in a subject. Devices, systems, and methods are provided that alter the functional structure of one or more inflammatory mediators in the peripheral blood of the subject. The device or system is useful in a method for treating an inflammatory disease or condition in the subject.
US08454541B2 Training apparatus for the disabled
Apparatus for disabled persons, comprising a skid which optionally may be equipped with wheels, to which skid is connected a device for tightening the user's knees.
US08454539B2 Method and device for detecting and preventing plantar ulcers
A method of detecting a risk of occurrence of a plantar ulcer includes the following steps: monitoring at least the temperature and pressure of the sole of at least one foot; as soon as one of the temperature and pressure parameters exceeds a threshold value, opening a first time window for monitoring the first parameter; if at the end of the first time window the first parameter still exceeds the threshold value, monitoring the second parameter during a second time window; and assigning a coefficient of risk to the event encountered.
US08454537B2 Guide wire with core having welded wire segments
An intravascular guide wire having two core materials joined together without the use of a connector tube or sleeve, the core materials being stainless steel and psuedoelastic metal alloy, nitinol. The core materials are joined to each other through an intermediate transition piece made essentially of nickel, which is welded on either side to the two core materials. In a multi-segment intravascular guide wire, discrete, high modulus and medium modulus core portions of different materials are welded to a shapeable, low modulus distal core portion made of a third material having a flattened, shapeable section at a most distal end that is not welded to but made from the distal core portion, so the flattened, shapeable section can be deformed to create a steerable tip. Processes such as simultaneous resistance and friction welding can be used to join the core portions.
US08454534B2 Blood collector device and blood analysis procedure
The present invention provides an improved arterialized earlobe blood collection device, and an improved process for blood analysis. The device and the process of the invention can be used in many unsual and/or risky situations, including collecting arterialized blood in space missions under microgravity environment and within ambulances or the like. The process of the present invention enables easier and faster blood analysis, since the blood collector device of the invention is coupled with an analyzing apparatus so as no blood or needle manipulation is required.
US08454532B2 Clutch and valving system for tetherless biopsy device
A biopsy device may include a needle, a cutter, and a handpiece. A vacuum pump may be provided in the handpiece for providing a vacuum to the needle and/or to the cutter. A motor may be provided in the handpiece to drive the vacuum pump and/or the cutter. A biopsy device may also include a valving mechanism within the handpiece for selectively communicating a vacuum and/or atmospheric air to the needle. A clutching mechanism may selectively provide communication between a motor and the cutter. Portions of a valving mechanism and a clutching mechanism may be integrally formed. A clutching and valving mechanism may be driven by a first motor; and a cutter and vacuum pump by a second motor. A biopsy device may include batteries for powering motors. A biopsy device may thus provide vacuum and power from within a handpiece, such that the biopsy device is tetherless.
US08454524B2 Wireless flow sensor
Devices and methods useful for non-invasively measuring and indicating a rate of fluid flow are disclosed. In one embodiment, a sensor housing adapted to received fluid flow therethrough is provided. A radio frequency tag and a masking element can be disposed in the sensor housing. The masking element and the radio frequency tag can be configured to move relative to one another. The relative positions or movement can alter the response of the radio frequency tag to a wireless signal (which can be emitted from an external reading device, for example) and thereby indicate a rate of fluid flowing through the housing. For example, in some embodiments, the masking element can selectively cover at least part of the radio frequency tag in correspondence to the flow rate, which can change a characteristic of the radio frequency tag's response to the wireless signal.
US08454523B2 Method and device for the intermittent occlusion of the coronary sinus
In a method for intermittently occluding the coronary sinus, in which in an alternating manner the coronary sinus is occluded by an occlusion device and the occlusion is released, the curve of the fluid pressure occurring in the coronary sinus after the release of the occlusion is estimated by calculation and the time of the beginning of the next occlusion is determined as a function of the estimated pressure curve.
US08454521B2 Sphygmomanometer
The objective of the present invention is to provide a sphygmomanometer that is easy to use. The sphygmomanometer according to the present invention measures blood pressure in accordance with an oscillation in an artery wall, resulting from an arterial pulse correspondent with a change in cuff pressure. It comprises a cuff that is connected to the sphygmomanometer main body by a tube, a display unit for displaying the results of blood pressure measurements, and an air supply unit for supplying air to, and thus pressurizing, the cuff, which is detachable from the sphygmomanometer main body. The air supply unit is screwed into the sphygmomanometer main body with a screw assembly, and the screwed-in state is preserved by a caulking ring. The air supply unit also comprises a filter for keeping dust from entering the sphygmomanometer main body.
US08454519B2 Miniature forward-looking ultrasound imaging mechanism enabled by local shape memory alloy actuator
The present invention relates to a new forward-looking ultrasound device including a local actuator embedded inside an elongate member such as a guide wire or catheter. The present invention includes an ultrasound transducer element configured to engage with the local actuator and rotate about an axis of rotation at least when the ultrasound transducer element and the local actuator are engaged. Also disclosed are methods of using the same.
US08454518B2 Ultrasonic probe
An ultrasonic probe is provided capable of eliminating difficulties in processing, increasing the directivity of ultrasonic waves, and obtaining a high-resolution diagnostic image. An ultrasonic probe 10 is configured to include a plurality of piezoelectric elements 1, an acoustic matching layer 2 provided on a front surface in the thickness direction at a subject side (upper side in the drawing) so as to correspond to the respective piezoelectric elements 1, a backing load member 3 provided, as necessary, on a rear surface (lower surface in the drawing) in the thickness direction of the piezoelectric elements 1 at a side opposite to the acoustic matching layer 2, and an acoustic lens 4 provided, as necessary, on the acoustic matching layer 2. The acoustic matching layer 2 is formed of a rubber elastic material and arranged in a non-divided, flat surface shape at one side of the plurality of piezoelectric elements 1.
US08454517B2 Ultrasonic diagnostic apparatus and ultrasonic diagnostic method
An ultrasonic diagnostic apparatus 10 comprises an ultrasonic transmitter unit 13,15, an ultrasonic receiving unit 13,17, an extracting unit 17, a filter unit and an adder unit 19c,21c. The ultrasonic transmitter unit 13,15 transmits ultrasonic varied at least one of phase and amplitude to an object. The ultrasonic receiving unit 13,17 receives ultrasonic echoes. The extracting unit 17 extracts a first nonlinear signal obtained through modulating the amplitude and a second linear signal obtained through modulating the phase from common ultrasonic echoes. The filter unit processes a filter process to the first nonlinear signal and the second nonlinear signal with at least two deferent sets of a middle frequency and a width of a band. The adder unit 19c,21c performs weighted addition to signals obtained through the first nonlinear signal and the second nonlinear signal according to a depth of the object.
US08454514B2 Ultrasound diagnostic apparatus and a medical image-processing apparatus
An ultrasound diagnostic apparatus 1 comprises an ultrasonic probe 2 for transmitting the ultrasound while three-dimensionally scanning, and receiving ultrasound reflected from biological tissue, an image processor 5 (and a signal processor 4) for generating image data for an MPR image based on results received thereof, an information memory 6 for storing cross-sectional-position information D showing a cross-section of this MPR image, a display part 81, and a controller 9. The image processor 5 generates image data for the new MPR image for the relevant cross-sectional position, based on the cross-sectional position shown in the cross-sectional-position information D1 obtained when the MPR image was obtained in the past and the received results obtained by the new three-dimensional scan performed with the ultrasonic probe 2. The controller 9 causes the display part 81 to display the new MPR image.
US08454513B2 Micro-machined medical devices, methods of fabricating microdevices, and methods of medical diagnosis, imaging, stimulation, and treatment
A medical device may include a micro-machined substrate, at least one thermo-electric assembly associated with the substrate, and a cooling system configured to configured to remove heat from the a region of the substrate proximal the substrate. According to various aspects, a method of clearing plaque from a blood vessel may include implanting a micro-device in the blood vessel, wherein the micro-device may include at least one ultrasonic transducer, and operably controlling the micro-device to emit high frequency ultrasonic waves for breaking up said plaque.
US08454512B2 Confocal photoacoustic microscopy with optical lateral resolution
A confocal photoacoustic microscopy system includes a laser configured to emit a light pulse, a focusing assembly configured to receive the light pulse and to focus the light pulse into an area inside an object, an ultrasonic transducer configured to receive acoustic waves emitted by the object in response to the light pulse, and an electronic system configured to process the acoustic waves and to generate an image of the area inside the object. The focusing assembly is further configured to focus the light pulse on the object in such a way that a focal point of the focusing assembly coincides with a focal point of the at least one ultrasonic transducer.
US08454509B1 Nanostructured composite material and biosensor comprising it
A nanostructured composite is provided which comprises a matrix comprising carbon nanofibers, and a biochemical receptor, especially an enzyme, immobilized in the matrix, where the carbon nanofibers have been subject to an oxidation treatment. In a preferred embodiment, the nanostructured composite further comprises a biomimetically synthesized silica matrix.
US08454503B2 Remote tissue retraction device
A medical device for managing tissue in an organ, such as the stomach, for retracting or positioning tissue and related organs to allow certain regions of the stomach to be acquired for a gastroplasty procedure. The medical device includes an elongated body having a proximal end and a distal end, and a tissue treatment device attached to the distal end of the elongated body. The tissue treatment device includes a first jaw opposite a second jaw, and each jaw is adapted to acquire tissue. A retractor is disposed along the tissue treatment device and adapted to be moveable from a delivery position to a retraction position to move or manage the tissue of the stomach. The medical device also includes a collapsible barrier disposed between the first and second jaws of the tissue treatment device to direct tissue into the first and second jaws separately.
US08454494B2 Support apparatus for gastric band system injector
A support apparatus connects with and provides fluid communication between a needle and a syringe. The support apparatus includes at least one arm that is configured to provide cantilever support of the needle and syringe while the needle is inserted in a patient. The arm engages the patient's skin, and may be rigid, malleable, hinged, stretchable, telescoping, and/or have other properties. The support apparatus may form part of an adapter that also includes a pressure sensor. The pressure sensor senses the pressure of fluid in a gastric band system when the needle is inserted in an injection port of the gastric band system. A cable may extend from the pressure sensor to a display device, and may include markings configured to provide measurement from the needle to a patient's xyphoid process. Such a measurement may be factored into a calculation to account for hydrostatic pressure differences in pressure readings.
US08454489B2 Implant comprising radioactive seeds
The present disclosure relates to an implant comprising at least two sheets of a biocompatible material, and at least one radioactive seed disposed between said sheets of material. The disclosure also relates to a method for treating a patient, comprising fixing to the tissue of the patient at least one implant comprising at least two sheets of a biocompatible material, and at least one radioactive seed disposed between said sheets of material.
US08454482B2 Body contouring apparatus and the method thereof
A body contouring apparatus and the method for using such apparatus is provided. The apparatus comprises a flexible rod, which has two ends and a laminar cross-section. The exercise device can switch between a rod shape and a ring shape. The exercise device has two connecting components, which are disposed at the two ends of the flexible rod, and at least one handle portion, which is female-connected to the flexible rod. When the two connecting components are connected to each other, the exercise device is in a ring shape; and when the two connecting components are not connected to each other, the exercise device is in a rod shape.
US08454478B2 Vertical arc exercise machine
An exercise device comprising: a foot support arranged on a frame for supporting a user standing upright on the foot support, the foot support being movable on the frame back and forth between a rearward position and a forward position along any one of a plurality of separate, reproducible user selectable segments of an overall arcuate path; the foot support being supported in a cantilevered arrangement on a rear linkage that is pivotally mounted on the frame for back and forth movement.
US08454477B2 Power transmitting device and vehicle having same mounted thereon
A power transmission configured with a mechanical pump that generates and deliver a fluid pressure to a clutch. An electromagnetic pump generates and delivers a fluid pressure to the clutch, and an accumulator connects the clutch and the electromagnetic pump, and accumulates fluid pressure acting there between. A switching valve selectively switches between connecting the mechanical pump side and the clutch in a fluid communicating manner and connecting the electromagnetic pump and the clutch in a fluid communicating manner. A valve drive portion that drives the switching valve so as to connect the mechanical pump side and the clutch when the mechanical pump is driving, and drives the switching valve so as to connect the electromagnetic pump and the clutch when the electromagnetic pump is driving in place of the mechanical pump.
US08454472B2 Multi-speed transmission with external drive gearsets
A transmission is provided having an input member, an output member, three planetary gear sets, two external gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. Each of the external gear sets includes first and second gears. The torque transmitting devices include clutches and brakes.
US08454470B2 Power generating apparatus and method for assisting engine
The present invention relates to a power generating apparatus and method for assisting an engine, capable of supplying auxiliary power to an engine transmission shaft when the engine is transmitting power to the engine transmission shaft via a gearbox. The power generating apparatus comprises: a power supply unit for providing a high voltage power source; a driver for converting the high voltage power source into a driving power source and transmitting same; and a direct-current motor for converting the driving power source transmitted by the driver into the auxiliary power to be transmitted to the engine transmission shaft; wherein the rotational speed of the direct-current motor driving the engine transmission shaft is enabled to be higher than that of the engine driving the engine transmission shaft, so as to supply the auxiliary power to the engine transmission shaft.
US08454469B2 Power split transmission with energy recovery
Power split drive (PSD) transmissions capable of energy recovery and suitable for use in automotive applications. Each PSD transmission includes a mechanical transmission system for mechanically transmitting mechanical power between a rotatable input shaft and a rotatable output shaft, and a hydraulic transmission system containing a fluid for hydraulically transmitting hydraulic power between the input shaft and the output shaft, and at least a third shaft operatively interconnected to one of the mechanical and hydraulic transmission systems. The hydraulic transmission system is operatively coupled by at least a first planetary gear train to the mechanical transmission system. According to the invention, the PSD further comprises means operatively associated with at least one of the mechanical and hydraulic transmission systems for storing and releasing energy within the PSD transmission, the energy storing and releasing means comprising a flywheel or an accumulator or a combination thereof.
US08454467B2 Power split transmission
The present invention relates to a power split transmission for a motor vehicle, having a mechanical and a hydrostatic power branch (3, 4) disposed parallel to each other and contacting a mutual drive shaft (1), wherein the hydrostatic power branch (4) consists of a hydro motor (6) coupled to a hydro pump (5) and is connected to the drive shaft (1) via a gear stage (7), wherein the branched power from the mechanical and hydrostatic power branch (3, 4) can be combined into a gear drive (13) disposed on the face side, said gear drive being subsequently connected to a drive shaft (2), wherein the mechanical power branch (3) further consists of two planetary gears (8, 9) having sun gears (10, 12), planetary gears (16, 17), and hollow gears (21, 22), wherein the sun gear (10) of the first planetary gear transmission (8) is placed directly on the drive shaft (1) while the sun gear (12) of the second planetary gear transmission (9) is in contact with the gear drive (13) via a sun shaft (11), and wherein the planetary gears (16, 17) of both stages (8, 9) are disposed in a coaxial manner and are supported on a mutual planetary carrier shaft (18).
US08454466B2 Hybrid powertrain system using selectable one-way clutches
A hybrid powertrain system includes first and second torque machines, a differential gear set including first, second and third elements, an output member, and first, second, and third selectable one-way clutches (SOWC). The first SOWC is configurable to prevent rotation of the third element of the differential gear set in a first rotational direction when controlled to a first activated state, and configurable to prevent rotation of the third element of the differential gear set in a second rotational direction opposite the first rotational direction when controlled to a second activated state. The first torque machine is coupled to the third element of the differential gear set only when the second SOWC is controlled to one of the activated states. And, the third element of the differential gear set is coupled to the input member only when the second and third SOWCs are each controlled to one of the activated states.
US08454464B2 Power transmission belt and method of making same
A method of making a belt including the steps of: (a) helically wrapping a fabric strip of predetermined width on a mandrel at a first helix angle; (b) helically winding a tensile cord onto the mandrel over the fabric at a second helix angle less than the first helix angle; (c) wrapping a sheet or a strip of elastomer material around the mandrel over the tensile cord; and (d) curing the elastomer material under pressure to form a belt sleeve. The mandrel may be grooved for making toothed belts. The fabric strip may be preformed. A resulting toothed belt has a fabric seam spanning several teeth and having a helix angle. The seam may be joined.
US08454460B2 Breakaway basketball rim assembly
A basketball rim mounting assembly permitting multi-directional deflection in response to extraordinary forces imposed on the rim has a fixed portion coupled to a backboard and a movable portion fixed to a basketball rim. The fixed portion can include a back plate secured to a front face of the backboard and a pair of bracket plates fixed to extend forward from the back plate. A tilt regulating structure can control the extent of deflection of the rim relative to the backboard such that the extraordinary force necessary to cause the rim to break-away from its normal position is the same in any direction. The tilt regulating structure can bias a rollable member within a detent formed in the back plate. A pivot axis member can be coupled to the tilt regulating structure to define the tilt and roll axes of the movable portion relative to the fixed portion.
US08454456B2 Low lift golf ball
A golf ball having a plurality of dimples formed on its outer surface, the outer surface of the golf ball being divided into plural areas comprising at least two groups of areas, a first group of areas containing a plurality of first dimples and a second group of areas containing a plurality of second dimples, the first and second groups of areas being arranged to form an Archimedean solid, the first and second groups of areas and dimple shapes and dimensions being configured such that the golf ball is spherically symmetrical as defined by the United States Golf Association (USGA) Symmetry Rules and such that the first and second groups of areas produce different aerodynamic effects, and the first dimples being of different dimensions from the second dimples.
US08454454B2 Golf ball having reduced surface hardness
A golf ball comprising a core and a cover, the core comprising an outer surface and a geometric center, the outer surface being treated with and comprising a fatty acid and/or fatty acid salt composition, the outer surface further having a first hardness and the geometric center having a second hardness, wherein the first hardness is the same as or different than the second hardness.
US08454438B2 Gaming machine having two image display devices
A gaming machine is provided which is capable of causing a player's eye to smoothly move from a main game to a rendering when the rendering is started.When a predetermined number or more of predetermined symbols are displayed on a first display as a result of a first game, a first control signal for displaying on the first display a dice image in a mode of rolling of the dice for determining progress of a second game that is different from the first game is output from a controller to the first display, as triggered by detection of an operation of an operating device by a player. After a first predetermined period of time has elapsed after output of the first control signal has been started, a second control signal for display control to display a dice image in a dice rolling mode on the second display is output from the controller to the second display.
US08454431B2 Characters interactions in a video game or other virtual environment managed by an automated system
In various embodiments, systems generate a video game or other virtual environment and player characters in the video game can form different types of interactions and relationships. Some relationships provide benefits and/or obligations. The video game facilitates the monitoring, forming and terminating of various kinds of relationships.
US08454428B2 Gaming machine performing real-time 3D rendering of gaming events
A gaming machine uses mathematical modeling and graphical displays to provide players with realistic depictions of gaming activities for wagering. Three-dimensional mathematical models are used to simulate real-world interactions of physical objects, with a display showing the player a visual representation of the game interactions. By providing the player with a realistic depiction of real-world gaming activities, a gaming machine according to the present invention involves the player in the wagered-upon activity to a greater extent than traditional gaming machines.
US08454427B2 Gaming device having wager dependent bonus game play
In one embodiment of the present invention, the player must wager a number of paylines to qualify for one of a plurality of bonus games. The highest required number of paylines qualifies the player to play the main or most elaborate bonus game. The main or first bonus game preferably has the highest average payout per credit wagered. This provides an incentive to the player to play the highest required number of paylines. In an embodiment, any number of paylines less than the highest required number or max lines qualifies the player to play a second bonus game. The second bonus game has an average payout per credit wagered that is slightly less than the main bonus game. This allows the incentive or disparity between payouts to be set by the game designer so that the player not wagering max lines or the highest required number is not overly disadvantaged.
US08454426B2 Wagering game with active paytable highlighting winning combinations
A gaming machine for playing a wagering game includes a game display, a display arrangement, and a controller. The game display is operable to display a randomly selected outcome of a wagering game in response to receiving a wager from a player. The display arrangement displays a video image and overlays the game display. The video image includes a paytable having paytable regions indicating respective winning combinations. The controller is in communication with the display arrangement, wherein in response to the randomly selected outcome including symbols of a winning symbol combination, the controller causes one or more aspects of the paytable region associated with the winning combinations to be distinguished from the other paytable regions.
US08454425B2 Gaming system and method of gaming
A gaming machine is provided that provides games in which a plurality of symbols are selected from a group of symbols and displayed on a display and, if a winning combination occurs, the gaming machine awards an award. The gaming machine comprises a user interface in communication with a game controller. The game controller is configured to provide a first game in which an event counter is maintained by the game controller and modified by the game controller each time a counter event occurs, and to provide a second game in which the game controller modifies the group of symbols to include a number of specific symbols. The number of specific symbols is dependent on the value of the event counter.
US08454424B2 Gaming machine and playing method thereof, which qualifies player to join special game through chance game run at the same time base game is run
A gaming terminal of the present invention a base game offering a chance of winning a payout according to a predetermined combination; a chance game offering a chance of obtaining a chance flag which qualifies a player to join a special game offering a chance of winning a higher payout than the base game; a terminal storage unit storing the number of chance flags; a terminal display which displays images of the base game, the chance game, and the special game; and a terminal controller, which performs the steps of: running the base game and the chance game at the same time; determining and awarding a payout according to a result of the base game; determining the number of chance flags according to a result of the chance game, and awarding a resulting number of chance flags; accumulatively storing in the terminal storage unit the number of chance flags awarded; and awarding a payout determined according to a result of the special game which is run when the number of the chance flags stored in the terminal storage unit equals or surpasses a predetermined.
US08454421B2 Method of playing a bingo-type game with a mechanical technological aid, and an apparatus and program product for playing the game
A method of playing a bingo-type game includes the steps of generating a result of the game and displaying a representation of the result. More specifically, the representation of the result of the game is displayed through a mechanical technological aid at an electronic play station. An apparatus for playing the game includes a server and the electronic play station in operative communication with the server. The server generates the called numbers, which correlate to the result of the game, and the electronic play station includes the mechanical technological aid for displaying the representation of the result of the game. A program product for playing the game is stored on computer readable media and includes a result program code for generating the result of the game and a display program code for displaying the representation of the result through the mechanical technological aid.
US08454418B2 Methods and apparatus for stringed controllers and instruments
Stringed instruments, game controllers, and related structures and methods are described. A game controller having one or more strings is described for a computer gaming application. A plurality of frets can be disposed on a fingerboard and underlying the strings. The frets may include electrically conductive zones that can be electrically insulated from each other, and each zone corresponds to a different string. A polyphonic pickup having a plurality of wire-wound coils coupled to corresponding magnetic returns can be included, and can be adapted to detect striking of at least one of the strings by a user of the game controller. Output signals may be sent from the controller to the gaming application indicative of fingering of the game controller and the time at which the strings of the game controller are struck. Multi-mode apparatus are also described. A stringed apparatus may be used as both a game controller and an instrument.
US08454417B2 Scent-based board game
The present invention includes a scent-based board game to challenge the olfactory sense of the player, and a method of play thereof, further including a game board having a start space, an end space and a set of spaces positioned between the start and end space; a scented card having a scent, the identity of the scent and an order; and positional markers. The players progress along the game path by following instructions on the game spaces, identifying the correct scent on the scented cards, and avoiding obstacles. The first player to arrive to the end space is declared as winner.
US08454411B2 Hand-held power tool system
A hand-held power tool system has a hand-held power tool, a guard unit, and a guard anti-rotation lock unit configured to prevent rotation between the guard unit and the hand-held power tool in a case where a tool of the hand-held power tool breaks during intended operation. The guard anti-rotation lock unit also is configured to prevent rotation between the guard unit and the hand-held power tool at a same time as the guard unit is attached to the hand-held power unit, when the guard unit is in a working position. Preferably, the guard anti-rotation lock unit is at least partially located on a closing unit which includes a clamping band and a pivotable lever. The anti-rotation lock unit preferably includes an anti-rotation lock element provided on the lever.
US08454405B2 Flying toy having gyroscopic and gliding components
Provided are flying devices and methods of manufacturing and launching same, in particular flying toys or other recreational items that are designed to be thrown through the air by a user participating in any one of a variety of throwing (i.e. “catch”) games. In particular, the concept is directed toward a flying disc having rotatably attached non-rotating (a.k.a. “gliding”) portions that are attached to the disc and provide an optical illusion, wherein the user (and, similarly, an observer) does not notice the spinning of the flying disc, but instead sees a flying craft that appears to have no propulsion, yet flies. While the non-rotating portions alter the airflow associated with a typical flying disc, they do not negatively affect the flight characteristics of the disc itself. Indeed, in certain embodiments, the non-rotating portions (e.g., ailerons) have been observed to improve the flight characteristics of typical flying discs.
US08454404B2 Method and apparatus for manufacturing sealed panel and method and apparatus for manufacturing plasma display panel
A method for manufacturing a sealed panel having a first substrate and a second substrate, including: a melting step of melting a sealing material which does not contain a binder for making the sealing material into paste form; a coating step of applying the melted sealing material onto a surface of the second substrate; and a sealing step of laminating the first substrate and the second substrate via the sealing material applied onto the surface of the second substrate.
US08454402B1 Systems and methods for performing a shift in a transmission in marine propulsion systems
Propulsion systems for marine vessels comprise an internal combustion engine rotating a driveshaft; an electric motor; a transmission selectively connecting the rotating driveshaft to a propulsor via a rotating gear; and a control circuit controlling the electric motor to slow rotation of the driveshaft and gear when a shift into the gear is requested.
US08454396B2 Terminal weld tab having a wire squeeze limiter
One embodiment includes an electrical connection terminal (20) including at least a first weld tab (22). The first weld tab (22) including an outer face (23) and a weldable inner face (33). The weldable inner face (33) includes a substantially planar first portion (25) and a substantially planar second portion (27), and wherein the first portion (25) and second portion (27) are not in the same plane.
US08454395B2 Electrical connector having improved contact member
An electrical connector (100) for mating with a mating connector includes a housing (1) defining a receiving cavity (10), a rear insulator (32), a central pin (7), a front insulator (31) and a contact member (5) received in the receiving cavity. The contact member includes a first through fourth side walls (513a-513d) surrounding an inserting slot (514), a pair of resilient beams (515) respectively bent from the second and the fourth side walls toward the inserting slot for clasping the mating connector. The first side wall includes a first edge portion (511) having a first protrusion (519) and a first cutout (518) in front of the first protrusion, and a second edge portion (512) having a second protrusion (516) engaged with the first cutout and a second cutout (517) behind the second protrusion and engaged with the first protrusion.
US08454392B2 System and method for coupling a portable electronic device to a charging/ data pod
An adaptor is provided. The adaptor comprises a first portion including a plug insertable into a port of a portable electronic device. The adaptor further comprises a second portion including at least one adaptor contact configured such that, when the plug of the first portion is inserted into the port and the portable electronic device is placed in a pod, the at least one adaptor contact abuts to at least one pod contact in the pod.
US08454390B2 Inline fuse holder assembly
An inline fuse holder assembly encloses a fuse assembly including a fuse, and first and second wire connectors at respective first and second longitudinal ends of the fuse assembly. The inline fuse holder assembly includes first and second components including respective first and second connectors. The first and second connectors include mateable, non-releasable connection components configured to connect the first and second components to one another and form a substantially waterproof, non-releasable connection upon connection. The first and second components together define an enclosure for enclosing an entirety of the fuse assembly when the first and second fuse holder components are connected to one another.
US08454389B2 Fuse-receiving device
The invention relates to a fuse-receiving device, in particular for junction boxes in photovoltaic systems, comprising a fastening web and receiving contact portions, arranged on the end faces of the fastening web, for contact blades of fuses, comprising insulating caps which are placed on the fastening web and cover the receiving contact portions at least in part and also have slot openings which allow the contact blades of a fuse to be guided through, the fastening web having at least one groove-shaped socket for an electrical busbar, into which socket a contact tab of one of the receiving contact portions is inserted, and at least one groove which extends along the axis of the fastening web being provided in at least one end face of the fastening web, and a holding member being provided which has a plug means which may be brought into engagement with the at least one groove.
US08454388B2 Micro-USB connector
A connector includes a plurality of terminals, a housing to fix these terminals, and a shield surrounding the housing. Each terminal comprises a mating portion, a soldering portion, and a connecting portion extending therebetween. The housing comprises a main body and a tongue portion extending forward from the main body and the shield comprises a top wall, a base, and two side walls positioned opposite each other, the walls forming a mating cavity with an opening at the front. The base is formed by the meeting of the two half bases, which are formed by the lower edges of the two side walls extending out toward each other, there is a first soldering leg on each half base, and the first soldering leg extend from a front edge of each half base first in a downward direction and then in a horizontal direction toward a rear of the connector.
US08454385B2 Coaxial cable connector with strain relief clamp
Coaxial cable connectors with a strain relief clamp. In one example embodiment, a coaxial cable connector for terminating a coaxial cable is provided. The coaxial cable includes an inner conductor, an insulating layer surrounding the inner conductor, an outer conductor surrounding the insulating layer, and a jacket surrounding the outer conductor. The coaxial cable connector includes an inner conductor clamp configured to engage the inner conductor, an outer conductor clamp configured to engage the outer conductor, a strain relief clamp configured to exert a first inwardly-directed radial force against the coaxial cable, and a moisture seal configured to exert a second inwardly-directed radial force against the jacket. The first force is greater than the second force.
US08454380B2 Card edge connector
A card edge connector includes an elongated housing having an upper wall and a lower wall defining a mating cavity therebetween and extending along a longitudinal direction. A plurality of terminal grooves are respectively defined in the upper wall and lower wall and in communication with the mating cavity. A plurality of contacts are respectively received in said terminal grooves. A pair of locking devices are disposed at opposite ends of the mating cavity and extend along a rear-to-front direction perpendicular to the longitudinal direction. A recess facing the upper wall is defined in the lower wall and extends along the longitudinal direction under condition that two longitudinal ends of the recess are closer to the upper wall than a middle portion of the recess.
US08454378B2 Connector
A connector is provided that may include first and second housings. The first housing may include a first body and a lock arm. The first body may include a first receptacle. The lock arm may be pivotably coupled to the first body. The second housing may include a second body having a second receptacle and a support member. The first and second housings may be engageable with each other in a first position and a second position and movable relative to each other from the first position to the second position. The lock arm may be deflectable relative to the support member when the first and second housings are in the first position. The support member may restrict deflection of the lock arm when the first and second housings are in the second position.
US08454377B2 System for electrically connecting batteries to electric vehicles
The connection system is designed to facilitate electrical and data connections between the battery and the electric vehicle. The connectors are designed with alignment mechanisms to account for initial misalignment of the battery and vehicle while still ensuring positive contact between them. The alignment mechanisms also introduce compliance into the system to ensure that the mechanical components of the system are not placed under unwanted loads or stresses. The connection system houses data connectors carrying communication signals as well as power connectors carrying high voltage electricity. The data connectors are shielded to prevent interference caused by proximity to the high voltage elements. The connection system uses no mechanical latching or locking mechanisms.
US08454373B2 Socket with lower contacts with configuration
A socket for receiving an IC (integrate circuit) package comprises an insulative housing and a plurality of contacts. The insulative housing defines a plurality of contact passageways for receiving the contacts. Each contact has a retaining portion, an elastic arm and a soldering portion, and the retaining portion is formed with a first part, a second part and a bending part between the first and the second parts. Each of the first and the second parts is formed with a protrusion on an outside lateral edge thereof away from the bending part for interfering with the contact passageway of the insulative housing to retain the contact to the insulative housing.
US08454372B2 Electrical connector with power plug and power socket
An electronic device includes a power plug and a power socket coupled to the power plug. The power plug includes a housing, two plug contacts, one conductive member, two conductive resilient pieces, and two magnetic members. The conductive resilient pieces are positioned in the housing, and are electrically connected to the conductive member. The magnetic members are positioned in the housing, and opposite to the at least two conductive resilient pieces. The power socket includes an inner housing, two socket contacts, and two metal pieces. The inner housing defines an assembly groove to receive the power plug. The metal pieces are positioned in the assembly groove of the inner housing, and are opposite to the magnetic members, such that a magnetic attraction force exerted between the metal pieces and the magnetic member actuates the power plug.
US08454371B2 Adhesive-backed chalkboard wall covering
An improved chalkboard marking surface comprises a rollable, flexible sheet of polypropylene having two sides that are opposite one another, each having a generally flat surface. On one side, a layer of adhesive is applied to the polypropylene substrate. On the same side of the polypropylene substrate, a selectively removable release sheet is preferably applied to the layer of adhesive for the purpose of keeping foreign materials from attaching to the adhesive when the chalkboard surface is not in use. On the reverse side of the polypropylene substrate, a layer of ink is applied which forms an abrasive surface after it dries, and importantly, results in a chalkboard surface that is lighter in weight.
US08454370B2 Submersible tablet for underwater or extreme environment
A tablet that is suitable for use underwater or in any extreme environment is provided. The tablet is designed, through the use of buoyant materials such as polystyrene, to have a slightly negative buoyancy at a depth of about fifty feet so that it can be very easy to manipulate underwater and will not sink or ascend rapidly if let go. A length of waterproof (plastic) vellum is stretched between two rollers to form a drawing or writing surface thereby enabling the user to easily record information on the vellum.
US08454369B2 Extensible exam language (XXL) protocol for computer based testing
A memory stores a plurality of first data structures, which includes element specific data objects indicating a classification of at least one of the plurality of segments of the test definition language, and second data structures, which include attribute specific data objects indicating at least one attribute of the segments of the test definition language implemented by a computer. A method for computer-based testing includes authoring a test specification and content of the at least one test using a test definition language, compiling the test specification and content of the at least one test to create a compiled test specification and content, which includes validating the test specification and content, storing the compiled test specification and content to a resource file, and retrieving the compiled test specification and content from the resource file during delivery of the test.
US08454366B2 Actuated support platform for video system
An actuated support frame for transmitting motion to a seat with respect to a ground as a function of motion signals associated with video output, comprises a frame. The frame is expandable/retractable along translational degrees of freedom. Support surfaces are provided on the frame. The support surfaces are displaceable with respect to one another by expansion/retraction of the frame so as to be sized to support a seat. Actuators are provided between the frame and the ground. The actuators receive signals and selectively displace the frame with respect to the ground in synchronization with a video output, whereby a seat supported on the frame is displaceable within the frame. A method for installing a seating system of a motion simulator system is also provided.
US08454364B2 Method for preparing a physical plaster model
The invention provides a method for creating a physical teeth model. The method comprises the following steps: providing a virtual three dimensional (3D) representation of a patient's dentition that comprises at least a region of the teeth that includes a tooth stump on which a crown is to be fitted or a region on to which a bridge is to be fitted; and preparing a physical model of the jaws of a subject from a blank, based on information from said virtual 3D image.